# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- GCR1_C PF12550.3 EIE75298.1 - 5.1e-26 90.3 0.7 5.1e-25 87.1 0.2 2.6 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes Pkinase PF00069.20 EIE75299.1 - 1.1e-55 188.6 0.0 1.3e-55 188.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE75299.1 - 5.6e-33 114.1 0.0 7.4e-33 113.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE75299.1 - 3.1e-10 39.5 0.0 4e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EIE75299.1 - 0.0085 15.1 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 EIE75299.1 - 0.014 14.2 0.3 0.022 13.5 0.2 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.18 EIE75299.1 - 0.065 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EIE75299.1 - 0.097 11.4 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Ank_2 PF12796.2 EIE75300.1 - 1.3e-18 67.0 3.1 1.2e-06 28.7 0.0 4.8 2 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 EIE75300.1 - 2.2e-17 61.8 7.9 0.0041 16.8 0.1 7.2 8 0 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.1 EIE75300.1 - 6.3e-15 54.8 5.5 0.0099 16.1 0.0 7.3 4 2 3 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIE75300.1 - 1.4e-13 49.6 7.1 0.36 11.2 0.0 8.4 10 0 0 10 10 10 4 Ankyrin repeat VPS9 PF02204.13 EIE75300.1 - 3.3e-11 43.1 2.1 7.1e-11 42.0 0.1 2.5 3 0 0 3 3 3 1 Vacuolar sorting protein 9 (VPS9) domain Ank_4 PF13637.1 EIE75300.1 - 2e-10 40.8 5.4 0.11 13.0 0.0 6.9 4 1 4 8 8 8 4 Ankyrin repeats (many copies) G-alpha PF00503.15 EIE75301.1 - 2.8e-108 362.0 7.4 9.2e-107 357.0 5.2 2.0 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EIE75301.1 - 2.3e-09 36.7 0.4 0.0021 17.3 0.0 2.8 2 1 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.15 EIE75301.1 - 0.00041 19.8 0.0 0.00093 18.7 0.0 1.6 1 0 0 1 1 1 1 CHC2 zinc finger AAA_29 PF13555.1 EIE75301.1 - 0.009 15.5 0.0 0.018 14.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 EIE75301.1 - 0.061 12.7 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family MCM PF00493.18 EIE75301.1 - 0.087 11.6 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 MCM2/3/5 family BOP1NT PF08145.7 EIE75302.1 - 7.6e-110 366.7 12.0 7.6e-110 366.7 8.3 2.0 2 0 0 2 2 2 1 BOP1NT (NUC169) domain WD40 PF00400.27 EIE75302.1 - 2.1e-32 109.7 4.5 2e-10 40.1 0.0 6.5 6 0 0 6 6 6 4 WD domain, G-beta repeat Nop14 PF04147.7 EIE75302.1 - 6.5 4.5 45.8 12 3.6 31.8 1.3 1 0 0 1 1 1 0 Nop14-like family ArfGap PF01412.13 EIE75303.1 - 7e-36 122.5 1.4 7e-36 122.5 1.0 2.4 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf Suf PF05843.9 EIE75303.1 - 0.06 13.0 7.4 0.11 12.1 5.1 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF2489 PF10675.4 EIE75303.1 - 0.1 12.2 5.3 0.27 10.9 3.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2489) FAD-SLDH PF12318.3 EIE75303.1 - 0.27 10.9 5.3 0.54 9.9 3.6 1.4 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase Proteasome PF00227.21 EIE75304.1 - 5e-52 175.9 0.0 6.2e-52 175.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 EIE75304.1 - 2.3e-14 52.3 0.8 6.4e-14 50.9 0.5 1.8 1 0 0 1 1 1 1 Proteasome beta subunits C terminal Ribosomal_L21e PF01157.13 EIE75305.1 - 4.8e-43 145.0 4.7 6.7e-43 144.5 3.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L21e DUF1989 PF09347.5 EIE75305.1 - 0.0022 17.4 0.0 0.0029 17.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) DUF3865 PF12981.2 EIE75305.1 - 0.07 12.9 0.1 0.088 12.5 0.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3865) Surface_Ag_2 PF01617.12 EIE75305.1 - 0.084 12.0 0.2 0.1 11.8 0.1 1.3 1 0 0 1 1 1 0 Surface antigen LRS4 PF10422.4 EIE75305.1 - 0.098 11.9 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 Ribosomal_S4 PF00163.14 EIE75306.1 - 2.6e-26 91.8 0.9 2.8e-26 91.7 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain PMT PF02366.13 EIE75308.1 - 4e-72 242.5 15.8 5.3e-72 242.1 10.9 1.2 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EIE75308.1 - 4.1e-44 150.4 1.6 4.1e-44 150.4 1.1 1.9 3 0 0 3 3 3 1 MIR domain PMT_2 PF13231.1 EIE75308.1 - 0.00046 20.1 15.4 0.0065 16.3 9.3 2.6 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase YwiC PF14256.1 EIE75308.1 - 9.1 6.3 12.4 2.1 8.4 3.1 2.8 2 1 1 3 3 3 0 YwiC-like protein E1-E2_ATPase PF00122.15 EIE75310.1 - 1.8e-59 200.5 2.7 1.8e-59 200.5 1.9 3.0 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EIE75310.1 - 2.3e-25 90.2 0.1 8.8e-24 85.1 0.1 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 EIE75310.1 - 7.8e-25 87.4 5.3 7.8e-25 87.4 3.7 3.0 4 0 0 4 4 4 1 Cation transporting ATPase, C-terminus Hydrolase_like2 PF13246.1 EIE75310.1 - 2.2e-18 65.9 0.0 4.1e-18 65.1 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EIE75310.1 - 1.4e-16 59.6 0.2 2.8e-14 52.3 0.0 2.8 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EIE75310.1 - 3e-14 53.6 0.0 6.4e-14 52.5 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EIE75310.1 - 0.00093 18.8 1.4 0.0053 16.3 0.7 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase COX6B PF02297.12 EIE75314.1 - 1.2e-18 66.8 5.3 1.4e-18 66.6 3.7 1.0 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb APOBEC_C PF05240.9 EIE75314.1 - 0.012 15.0 0.6 0.017 14.5 0.4 1.3 1 0 0 1 1 1 0 APOBEC-like C-terminal domain OTOS PF15182.1 EIE75314.1 - 0.035 13.7 0.1 0.047 13.3 0.1 1.2 1 0 0 1 1 1 0 Otospiralin UPF0203 PF05254.7 EIE75314.1 - 4.8 7.1 7.6 9.3 6.1 0.3 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) Sugar_tr PF00083.19 EIE75315.1 - 1.4e-118 396.3 17.6 1.7e-118 396.0 12.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIE75315.1 - 2.1e-21 76.0 27.8 2.1e-21 76.0 19.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EIE75315.1 - 1e-05 24.0 2.2 1e-05 24.0 1.5 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Lig_chan PF00060.21 EIE75315.1 - 0.14 11.8 0.6 0.45 10.2 0.1 2.0 1 1 0 1 1 1 0 Ligand-gated ion channel Cyanate_lyase PF02560.9 EIE75316.1 - 4.4e-19 67.7 0.0 7.3e-19 67.0 0.0 1.3 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_3 PF01381.17 EIE75316.1 - 0.027 14.3 0.0 0.043 13.6 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix Sigma70_r4_2 PF08281.7 EIE75316.1 - 0.029 13.8 0.0 0.09 12.2 0.0 1.7 2 0 0 2 2 2 0 Sigma-70, region 4 Bac_DnaA_C PF08299.6 EIE75316.1 - 0.054 13.3 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein helix-turn-helix HTH_31 PF13560.1 EIE75316.1 - 0.059 13.5 0.0 0.085 13.0 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain SPC25 PF06703.6 EIE75317.1 - 3.5e-37 127.4 1.6 4e-37 127.2 1.1 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) Pyr_redox_2 PF07992.9 EIE75318.1 - 7.2e-42 143.5 2.1 1.1e-41 142.9 1.5 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EIE75318.1 - 6.1e-31 106.6 0.1 1.8e-30 105.2 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 EIE75318.1 - 3.5e-17 62.5 6.4 1.3e-16 60.7 0.2 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EIE75318.1 - 3.6e-09 36.2 0.1 8.1e-09 35.0 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.19 EIE75318.1 - 2.8e-06 26.4 4.4 0.0012 17.8 0.8 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EIE75318.1 - 0.00025 21.1 1.4 0.0025 17.8 0.4 2.7 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EIE75318.1 - 0.00045 19.1 1.3 0.001 18.0 0.9 1.7 1 1 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 EIE75318.1 - 0.00056 18.8 10.2 0.0054 15.6 3.6 2.7 2 1 1 3 3 3 2 FAD binding domain HI0933_like PF03486.9 EIE75318.1 - 0.002 16.6 7.8 0.16 10.4 1.0 3.3 3 1 1 4 4 4 2 HI0933-like protein K_oxygenase PF13434.1 EIE75318.1 - 0.0065 15.4 1.1 0.02 13.8 0.0 2.2 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.16 EIE75318.1 - 0.0092 15.5 1.2 0.085 12.4 0.0 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.1 EIE75318.1 - 0.017 15.1 1.0 0.045 13.7 0.7 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EIE75318.1 - 0.018 14.1 0.1 0.039 13.0 0.1 1.6 1 0 0 1 1 1 0 Thi4 family 2-Hacid_dh_C PF02826.14 EIE75318.1 - 0.026 13.6 2.3 0.041 13.0 0.0 2.4 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 EIE75318.1 - 0.055 12.8 0.1 0.096 12.0 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 EIE75318.1 - 0.058 13.0 0.1 0.058 13.0 0.1 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain LCM PF04072.9 EIE75319.1 - 0.017 14.6 0.0 0.032 13.8 0.0 1.4 1 0 0 1 1 1 0 Leucine carboxyl methyltransferase Cript PF10235.4 EIE75319.1 - 0.98 9.8 5.7 0.81 10.0 2.0 2.5 2 1 0 2 2 2 0 Microtubule-associated protein CRIPT zf-C3HC4_3 PF13920.1 EIE75319.1 - 4.2 7.1 9.2 0.23 11.1 1.9 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Septin PF00735.13 EIE75320.1 - 4.7e-97 324.4 0.3 7.8e-97 323.6 0.2 1.3 1 0 0 1 1 1 1 Septin GTP_EFTU PF00009.22 EIE75320.1 - 0.0024 17.3 0.1 0.045 13.1 0.0 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamitin PF04912.9 EIE75320.1 - 0.0048 15.7 5.8 0.007 15.2 4.0 1.2 1 0 0 1 1 1 1 Dynamitin Dynamin_N PF00350.18 EIE75320.1 - 0.17 11.6 2.6 0.51 10.1 0.0 2.3 2 0 0 2 2 2 0 Dynamin family APG6 PF04111.7 EIE75320.1 - 3 6.7 10.5 4.4 6.2 7.3 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 cNMP_binding PF00027.24 EIE75321.1 - 1.4e-29 101.6 2.0 1.3e-18 66.5 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.12 EIE75321.1 - 1.5e-08 33.8 1.1 3.1e-08 32.9 0.8 1.6 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit FRD2 PF03197.8 EIE75321.1 - 0.13 12.8 4.5 0.1 13.1 0.7 2.3 2 0 0 2 2 2 0 Bacteriophage FRD2 protein Zn_peptidase_2 PF04298.7 EIE75323.1 - 0.084 12.2 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase PAT1 PF09770.4 EIE75324.1 - 9.2 4.3 37.4 12 4.0 25.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RasGEF PF00617.14 EIE75325.1 - 4.8e-39 134.0 2.0 1.1e-38 132.8 1.4 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EIE75325.1 - 7.1e-25 87.1 1.2 7.1e-25 87.1 0.9 3.2 3 0 0 3 3 3 1 RasGEF N-terminal motif Pyridoxal_deC PF00282.14 EIE75326.1 - 1.4e-78 263.9 0.0 1.9e-78 263.4 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EIE75326.1 - 8.1e-06 24.8 0.0 1.5e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EIE75326.1 - 0.0007 18.8 0.0 0.0011 18.1 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase Peptidase_M48 PF01435.13 EIE75327.1 - 3.7e-43 147.6 0.0 5.1e-43 147.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.6 EIE75327.1 - 0.028 13.4 4.2 0.018 13.9 1.1 2.0 3 0 0 3 3 3 0 BlaR1 peptidase M56 DUF2268 PF10026.4 EIE75327.1 - 0.03 13.6 0.1 0.053 12.8 0.1 1.3 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) Clp1 PF06807.9 EIE75329.1 - 7e-08 32.4 0.1 0.0025 17.6 0.0 2.9 1 1 1 2 2 2 2 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 EIE75329.1 - 7.1e-08 32.2 0.0 1.1e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B zf-H2C2_2 PF13465.1 EIE75330.1 - 1.1e-14 53.8 16.6 1.8e-07 31.1 0.6 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EIE75330.1 - 4.2e-06 26.7 8.8 0.0061 16.8 0.5 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EIE75330.1 - 3.1e-05 24.0 18.3 9.2e-05 22.5 0.9 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_5 PF13909.1 EIE75330.1 - 0.0062 16.7 7.6 0.0083 16.2 1.7 3.2 3 0 0 3 3 3 1 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.3 EIE75330.1 - 0.0064 16.6 2.1 2.6 8.3 0.8 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-CGNR PF11706.3 EIE75330.1 - 0.32 10.5 2.4 1.6 8.2 0.2 2.2 2 0 0 2 2 2 0 CGNR zinc finger Ogr_Delta PF04606.7 EIE75330.1 - 0.6 9.8 3.9 3 7.5 0.1 2.5 1 1 1 2 2 2 0 Ogr/Delta-like zinc finger HAD_2 PF13419.1 EIE75332.1 - 3.5e-12 46.8 0.0 5.9e-12 46.1 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EIE75332.1 - 0.033 13.8 0.1 0.2 11.4 0.0 2.1 2 0 0 2 2 2 0 HAD-hyrolase-like Hydrolase PF00702.21 EIE75332.1 - 0.091 13.1 0.0 0.098 13.0 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Lipase_3 PF01764.20 EIE75333.1 - 1.3e-38 131.8 0.0 2.1e-38 131.1 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 EIE75333.1 - 0.00013 21.4 0.0 0.0003 20.2 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Esterase PF00756.15 EIE75333.1 - 0.013 14.8 0.0 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Abhydrolase_6 PF12697.2 EIE75333.1 - 0.047 13.5 0.0 0.064 13.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIE75333.1 - 0.11 12.3 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Pex14_N PF04695.8 EIE75335.1 - 0.049 13.6 0.2 0.074 13.0 0.1 1.3 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region P12 PF12669.2 EIE75335.1 - 0.28 11.4 9.7 0.093 12.9 5.0 1.5 1 1 0 1 1 1 0 Virus attachment protein p12 family DDE_3 PF13358.1 EIE75336.1 - 0.0053 16.5 0.0 0.0063 16.2 0.0 1.3 1 1 0 1 1 1 1 DDE superfamily endonuclease NAC PF01849.13 EIE75338.1 - 1.4e-20 72.5 0.0 2.5e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 NAC domain Ecl1 PF12855.2 EIE75339.1 - 9e-09 34.4 7.5 9e-09 34.4 5.2 1.5 2 0 0 2 2 2 1 Life-span regulatory factor PLATZ PF04640.9 EIE75339.1 - 0.43 10.8 4.9 0.71 10.1 3.4 1.3 1 0 0 1 1 1 0 PLATZ transcription factor DUF2116 PF09889.4 EIE75339.1 - 0.83 9.4 3.4 1.4 8.7 2.3 1.3 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) adh_short PF00106.20 EIE75340.1 - 4.7e-34 117.7 0.0 6.6e-34 117.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIE75340.1 - 3e-19 69.7 0.0 3.8e-19 69.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIE75340.1 - 8.2e-13 48.4 0.0 1.2e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EIE75340.1 - 9.2e-06 24.7 0.1 1.6e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 EIE75340.1 - 0.00029 20.3 0.5 0.00062 19.2 0.1 1.9 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIE75340.1 - 0.00038 20.5 0.1 0.00066 19.7 0.1 1.6 1 1 0 1 1 1 1 NADH(P)-binding Med15_fungi PF05397.7 EIE75340.1 - 0.036 14.0 0.4 0.062 13.2 0.2 1.4 1 0 0 1 1 1 0 Mediator complex subunit 15 Peptidase_S8 PF00082.17 EIE75341.1 - 1.5e-41 142.3 3.7 2e-41 142.0 2.6 1.1 1 0 0 1 1 1 1 Subtilase family WD40 PF00400.27 EIE75342.1 - 4.9e-52 172.0 24.6 9.9e-09 34.7 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EIE75342.1 - 7.7e-05 22.4 0.0 0.0089 15.7 0.0 2.5 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 EIE75342.1 - 0.047 12.4 0.4 10 4.7 0.0 2.8 4 0 0 4 4 4 0 Nup133 N terminal like Sel1 PF08238.7 EIE75343.1 - 3e-30 103.9 15.9 1.2e-07 32.1 0.1 7.0 7 0 0 7 7 7 5 Sel1 repeat TPR_16 PF13432.1 EIE75343.1 - 0.074 13.7 4.5 2.5 8.8 0.1 3.9 4 1 0 4 4 4 0 Tetratricopeptide repeat OS-D PF03392.8 EIE75343.1 - 0.089 12.7 0.7 0.17 11.8 0.5 1.5 1 0 0 1 1 1 0 Insect pheromone-binding family, A10/OS-D DUF1640 PF07798.6 EIE75344.1 - 0.0044 17.0 4.9 0.0052 16.8 3.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1640) DUF4618 PF15397.1 EIE75344.1 - 0.027 13.8 0.3 0.035 13.4 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) Lge1 PF11488.3 EIE75344.1 - 0.05 13.7 0.1 0.082 13.1 0.1 1.4 1 0 0 1 1 1 0 Transcriptional regulatory protein LGE1 DASH_Hsk3 PF08227.6 EIE75344.1 - 0.093 12.9 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 DASH complex subunit Hsk3 like Enkurin PF13864.1 EIE75344.1 - 0.12 12.6 0.9 0.16 12.1 0.6 1.6 1 1 0 1 1 1 0 Calmodulin-binding RRM_1 PF00076.17 EIE75345.1 - 1.1e-33 114.7 0.1 9.3e-16 57.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE75345.1 - 1.4e-27 95.4 0.0 8.4e-14 51.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE75345.1 - 1e-17 63.6 0.0 8.7e-10 38.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EIE75345.1 - 7.5e-06 25.6 0.1 0.014 15.1 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif BUD22 PF09073.5 EIE75345.1 - 0.24 10.4 57.9 0.34 9.9 40.1 1.1 1 0 0 1 1 1 0 BUD22 Ndc1_Nup PF09531.5 EIE75345.1 - 0.51 8.6 8.6 0.64 8.3 5.9 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF966 PF06136.8 EIE75345.1 - 2.3 7.5 27.3 3.6 6.9 18.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF966) LMBR1 PF04791.11 EIE75345.1 - 9.2 4.7 12.8 10 4.5 8.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Fungal_trans PF04082.13 EIE75347.1 - 1.1e-09 37.5 0.0 2.5e-09 36.3 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Phage_term_smal PF05944.7 EIE75347.1 - 0.11 12.1 0.5 4.7 6.8 0.0 2.9 1 1 1 3 3 3 0 Phage small terminase subunit Ded_cyto PF06920.8 EIE75349.1 - 1e-37 129.1 0.2 2.8e-37 127.7 0.2 1.8 1 0 0 1 1 1 1 Dedicator of cytokinesis Methyltransf_16 PF10294.4 EIE75349.1 - 5.4e-28 97.6 1.3 1.8e-27 95.8 0.9 1.9 1 0 0 1 1 1 1 Putative methyltransferase DOCK-C2 PF14429.1 EIE75349.1 - 1.9e-25 89.5 1.5 7.6e-24 84.3 0.1 3.5 2 1 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins MTS PF05175.9 EIE75349.1 - 0.0043 16.4 0.0 0.0086 15.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Pkinase PF00069.20 EIE75350.1 - 1.2e-32 113.0 1.0 9.4e-17 61.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIE75350.1 - 7.6e-09 35.0 0.2 0.00072 18.6 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EIE75350.1 - 0.0094 14.7 0.0 0.014 14.2 0.0 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase RRM_6 PF14259.1 EIE75351.1 - 1.6e-08 34.3 0.0 3.9e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EIE75351.1 - 4.7e-05 22.9 0.0 0.00032 20.2 0.0 2.2 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NDT80_PhoG PF05224.7 EIE75352.1 - 3.4e-35 121.7 0.0 3.4e-35 121.7 0.0 2.5 2 2 0 2 2 2 1 NDT80 / PhoG like DNA-binding family Pyr_redox PF00070.22 EIE75353.1 - 9.4e-15 54.7 0.0 4.6e-09 36.5 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EIE75353.1 - 3.4e-12 46.6 0.2 1.3e-09 38.2 0.2 4.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EIE75353.1 - 7.4e-09 34.9 0.0 0.039 12.8 0.0 4.2 3 2 2 5 5 5 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EIE75353.1 - 2.3e-08 34.3 0.0 0.011 15.7 0.0 3.3 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIE75353.1 - 1.7e-07 31.1 0.0 0.02 14.8 0.0 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EIE75353.1 - 4.8e-05 22.5 0.0 0.13 11.2 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_9 PF13454.1 EIE75353.1 - 7.4e-05 22.5 2.2 4.7 6.9 0.0 4.6 3 2 2 5 5 4 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EIE75353.1 - 0.00026 20.0 0.0 0.19 10.6 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein TrkA_N PF02254.13 EIE75353.1 - 0.00066 19.6 0.1 0.42 10.6 0.0 2.6 2 0 0 2 2 2 2 TrkA-N domain K_oxygenase PF13434.1 EIE75353.1 - 0.00074 18.5 0.0 0.24 10.2 0.0 2.7 2 1 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.9 EIE75353.1 - 0.0076 14.9 0.0 0.056 12.0 0.0 2.0 2 0 0 2 2 2 1 Tryptophan halogenase NAD_binding_7 PF13241.1 EIE75353.1 - 0.017 15.3 0.0 2.5 8.3 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding GIDA PF01134.17 EIE75353.1 - 0.044 12.6 0.2 4.6 6.0 0.1 3.4 4 1 0 4 4 4 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 EIE75353.1 - 0.06 12.9 0.0 2 7.9 0.0 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain ThiF PF00899.16 EIE75353.1 - 0.065 13.0 0.0 3.7 7.3 0.0 2.4 2 0 0 2 2 2 0 ThiF family UDPG_MGDP_dh_N PF03721.9 EIE75353.1 - 0.065 12.6 0.6 4.3 6.6 0.0 2.9 3 0 0 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Spermine_synth PF01564.12 EIE75353.1 - 0.16 10.8 0.1 0.37 9.6 0.0 1.6 2 0 0 2 2 2 0 Spermine/spermidine synthase E1-E2_ATPase PF00122.15 EIE75354.1 - 1.2e-59 201.2 0.2 1.2e-59 201.2 0.1 3.0 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 EIE75354.1 - 3.6e-22 79.8 0.1 7e-22 78.8 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EIE75354.1 - 2.3e-14 52.6 0.0 6.7e-14 51.1 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EIE75354.1 - 3.6e-12 46.8 0.1 7.1e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EIE75354.1 - 3.3e-05 23.5 0.3 0.00014 21.5 0.1 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase NDT80_PhoG PF05224.7 EIE75355.1 - 4.3e-41 140.9 0.2 1e-40 139.7 0.2 1.6 1 1 0 1 1 1 1 NDT80 / PhoG like DNA-binding family bZIP_2 PF07716.10 EIE75356.1 - 1.6e-11 43.8 18.4 4.5e-09 36.0 8.6 2.4 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.16 EIE75356.1 - 1.4e-08 34.5 15.5 1.4e-08 34.5 10.7 2.3 2 1 1 3 3 2 2 bZIP transcription factor CCDC155 PF14662.1 EIE75356.1 - 5.3e-05 22.9 3.9 5.3e-05 22.9 2.7 1.4 1 1 0 1 1 1 1 Coiled-coil region of CCDC155 Cep57_CLD_2 PF14197.1 EIE75356.1 - 0.0022 17.9 1.9 0.0052 16.7 1.3 1.7 1 0 0 1 1 1 1 Centrosome localisation domain of PPC89 DUF4618 PF15397.1 EIE75356.1 - 0.0025 17.1 4.3 0.0032 16.8 3.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) bZIP_Maf PF03131.12 EIE75356.1 - 0.0028 17.9 11.2 0.0048 17.1 7.4 1.7 1 1 1 2 2 2 1 bZIP Maf transcription factor Lectin_N PF03954.9 EIE75356.1 - 0.0058 16.0 0.9 0.0095 15.3 0.6 1.4 1 0 0 1 1 1 1 Hepatic lectin, N-terminal domain IncA PF04156.9 EIE75356.1 - 0.017 14.7 6.5 0.022 14.3 4.5 1.1 1 0 0 1 1 1 0 IncA protein DUF972 PF06156.8 EIE75356.1 - 0.022 15.0 4.7 0.022 15.0 3.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF972) APG6 PF04111.7 EIE75356.1 - 0.024 13.7 7.6 0.028 13.4 5.3 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Rootletin PF15035.1 EIE75356.1 - 0.03 14.3 6.8 0.042 13.8 4.7 1.2 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion YojJ PF10372.4 EIE75356.1 - 0.031 14.1 0.3 0.048 13.5 0.2 1.3 1 0 0 1 1 1 0 Bacterial membrane-spanning protein N-terminus Adeno_PIX PF03955.9 EIE75356.1 - 0.081 13.4 1.3 0.12 12.8 0.9 1.3 1 0 0 1 1 1 0 Adenovirus hexon-associated protein (IX) V_ATPase_I PF01496.14 EIE75356.1 - 0.087 10.6 2.7 0.099 10.4 1.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Pigment_DH PF06324.6 EIE75356.1 - 0.11 11.7 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Pigment-dispersing hormone (PDH) TPR_MLP1_2 PF07926.7 EIE75356.1 - 0.13 12.0 10.8 0.2 11.4 7.5 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF3450 PF11932.3 EIE75356.1 - 0.15 11.3 4.8 0.21 10.8 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF342 PF03961.8 EIE75356.1 - 0.17 10.3 3.6 0.18 10.2 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Mnd1 PF03962.10 EIE75356.1 - 0.21 11.2 6.3 0.26 10.9 4.4 1.1 1 0 0 1 1 1 0 Mnd1 family ADIP PF11559.3 EIE75356.1 - 0.22 11.4 11.2 0.46 10.3 7.5 1.6 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF4613 PF15390.1 EIE75356.1 - 0.24 9.5 4.5 0.27 9.3 3.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Bap31 PF05529.7 EIE75356.1 - 0.27 10.6 5.4 0.35 10.3 3.8 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like DivIC PF04977.10 EIE75356.1 - 0.33 10.4 7.6 0.31 10.5 1.2 2.5 1 1 2 3 3 3 0 Septum formation initiator Jnk-SapK_ap_N PF09744.4 EIE75356.1 - 0.36 10.8 7.5 0.49 10.3 5.2 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF2968 PF11180.3 EIE75356.1 - 0.78 9.0 8.0 1.4 8.2 5.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2968) DUF724 PF05266.9 EIE75356.1 - 0.95 9.0 10.3 1.3 8.6 7.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) FlxA PF14282.1 EIE75356.1 - 0.95 9.4 7.9 0.51 10.3 3.9 1.7 1 1 0 1 1 1 0 FlxA-like protein DUF3552 PF12072.3 EIE75356.1 - 1 8.5 12.1 1.4 8.1 8.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) M_domain PF12938.2 EIE75356.1 - 1.3 8.8 4.9 8.3 6.1 3.4 2.0 1 1 0 1 1 1 0 M domain of GW182 DUF4140 PF13600.1 EIE75356.1 - 1.4 9.4 7.6 17 5.8 5.2 2.0 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) TMF_DNA_bd PF12329.3 EIE75356.1 - 4.2 7.2 12.6 0.43 10.4 4.8 2.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Pkinase PF00069.20 EIE75357.1 - 9.2e-62 208.5 0.0 1e-61 208.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE75357.1 - 6.9e-26 90.8 0.0 1.2e-25 90.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE75357.1 - 0.0053 15.7 0.0 0.0054 15.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Ribosomal_S3_C PF00189.15 EIE75358.1 - 2.9e-14 53.0 0.1 4.9e-14 52.2 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 EIE75358.1 - 4.9e-14 51.6 0.1 8e-14 50.9 0.1 1.4 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.3 EIE75358.1 - 0.0065 16.7 0.0 0.011 15.9 0.0 1.4 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 Rpp20 PF12328.3 EIE75359.1 - 2.4e-09 37.0 0.9 6.7e-07 29.0 0.6 2.1 1 1 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.16 EIE75359.1 - 3.8e-07 29.5 0.2 5.4e-07 29.1 0.1 1.3 1 0 0 1 1 1 1 Alba Imm7 PF15588.1 EIE75359.1 - 0.11 12.5 0.0 0.16 12.0 0.0 1.4 1 1 0 1 1 1 0 Immunity protein 7 Acetyltransf_CG PF14542.1 EIE75362.1 - 4.6e-15 55.2 0.0 6.3e-15 54.8 0.0 1.2 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_1 PF00583.19 EIE75362.1 - 0.074 13.0 0.0 0.095 12.7 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family DGF-1_C PF11040.3 EIE75362.1 - 1.5 8.7 6.2 13 5.7 0.4 2.2 1 1 1 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus DcpS_C PF11969.3 EIE75363.1 - 1.3e-18 67.3 0.0 1.5e-18 67.1 0.0 1.0 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 EIE75363.1 - 4e-11 43.3 0.1 5.1e-11 42.9 0.1 1.1 1 0 0 1 1 1 1 HIT domain CwfJ_C_1 PF04677.10 EIE75363.1 - 0.00036 20.1 0.0 0.00041 19.9 0.0 1.1 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Pkinase PF00069.20 EIE75364.1 - 5.8e-49 166.5 0.0 9.8e-49 165.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE75364.1 - 1.2e-19 70.4 0.0 2.8e-19 69.2 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE75364.1 - 3.6e-05 22.8 0.1 0.014 14.4 0.0 2.2 2 0 0 2 2 2 2 Kinase-like DUF4611 PF15387.1 EIE75364.1 - 0.0098 16.0 1.1 0.0098 16.0 0.7 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4611) Kdo PF06293.9 EIE75364.1 - 0.022 13.8 0.0 0.037 13.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CAF-1_p150 PF11600.3 EIE75364.1 - 0.18 11.1 2.7 0.27 10.5 1.8 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal PBP1_TM PF14812.1 EIE75364.1 - 2.2 8.6 8.5 0.47 10.7 2.5 2.3 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TLP-20 PF06088.6 EIE75364.1 - 3.3 7.3 9.2 0.92 9.1 3.2 2.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) ATP-synt_C PF00137.16 EIE75365.1 - 2.9e-30 103.9 30.2 6.7e-19 67.5 7.8 2.1 2 0 0 2 2 2 2 ATP synthase subunit C TCR_zetazeta PF11628.3 EIE75365.1 - 0.42 10.1 5.7 0.94 8.9 0.7 2.3 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 zeta chain PT-VENN PF04829.8 EIE75365.1 - 2.1 7.9 4.4 2.7 7.6 2.1 1.8 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif YlzJ PF14035.1 EIE75366.1 - 1.1 9.4 4.5 13 5.8 0.0 3.3 3 0 0 3 3 3 0 YlzJ-like protein Imm47 PF15586.1 EIE75367.1 - 0.076 12.8 0.1 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Immunity protein 47 Brix PF04427.13 EIE75368.1 - 2.7e-38 131.5 0.2 3.6e-38 131.1 0.2 1.2 1 0 0 1 1 1 1 Brix domain POPLD PF08170.7 EIE75370.1 - 5.1e-28 96.7 0.2 1.1e-27 95.7 0.1 1.6 1 0 0 1 1 1 1 POPLD (NUC188) domain POP1 PF06978.6 EIE75370.1 - 3e-17 62.8 13.9 9.7e-17 61.2 4.7 2.7 2 1 1 3 3 3 2 Ribonucleases P/MRP protein subunit POP1 GCV_T PF01571.16 EIE75370.1 - 1.1e-07 31.4 0.0 0.00041 19.7 0.0 2.3 2 0 0 2 2 2 2 Aminomethyltransferase folate-binding domain MFS_1 PF07690.11 EIE75371.1 - 3.1e-23 82.0 46.0 6.5e-22 77.7 30.4 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIE75371.1 - 3.7e-11 42.2 33.7 1.3e-10 40.4 7.2 3.3 1 1 0 2 2 2 2 Sugar (and other) transporter CotH PF08757.6 EIE75372.1 - 2e-30 106.1 7.9 4.5e-21 75.4 2.6 2.1 1 1 1 2 2 2 2 CotH protein Tim54 PF11711.3 EIE75374.1 - 6.7e-57 192.8 1.0 6.5e-40 136.8 0.2 2.1 1 1 1 2 2 2 2 Inner membrane protein import complex subunit Tim54 Peptidase_S8 PF00082.17 EIE75375.1 - 9.6e-53 179.1 0.7 1.7e-52 178.3 0.5 1.4 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 EIE75375.1 - 3.5e-30 103.6 0.6 7e-30 102.6 0.4 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain CTDII PF01556.13 EIE75376.1 - 1.9e-28 98.1 4.5 8e-20 70.5 0.0 3.2 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 EIE75376.1 - 1.6e-26 91.7 5.8 2.8e-26 91.0 4.0 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EIE75376.1 - 2.3e-09 37.1 20.4 4.5e-09 36.2 14.1 1.5 1 0 0 1 1 1 1 DnaJ central domain Glyco_hydro_15 PF00723.16 EIE75378.1 - 2.1e-92 310.0 0.0 2.7e-92 309.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_21 PF03370.8 EIE75378.1 - 7e-19 67.8 5.2 7e-19 67.8 3.6 1.8 2 0 0 2 2 2 1 Putative phosphatase regulatory subunit CBM_25 PF03423.8 EIE75378.1 - 0.086 12.9 4.0 10 6.2 0.3 3.2 3 0 0 3 3 3 0 Carbohydrate binding domain (family 25) Sporozoite_P67 PF05642.6 EIE75378.1 - 8.2 4.1 10.4 13 3.4 7.2 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RTA1 PF04479.8 EIE75382.1 - 7.2e-36 123.7 8.8 7.2e-36 123.7 6.1 1.6 1 1 1 2 2 2 1 RTA1 like protein Lipase_3 PF01764.20 EIE75383.1 - 1.3e-37 128.5 0.0 2.1e-37 127.8 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 EIE75383.1 - 0.00011 21.6 0.0 0.00021 20.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Esterase PF00756.15 EIE75383.1 - 0.014 14.8 0.0 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Abhydrolase_6 PF12697.2 EIE75383.1 - 0.016 15.0 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIE75383.1 - 0.071 12.8 0.0 0.18 11.5 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.8 EIE75383.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein SyrA PF11089.3 EIE75384.1 - 0.12 12.1 0.1 0.15 11.8 0.1 1.2 1 0 0 1 1 1 0 Exopolysaccharide production repressor Popeye PF04831.8 EIE75385.1 - 0.051 13.3 2.7 0.13 12.0 0.2 2.6 3 0 0 3 3 3 0 Popeye protein conserved region NAD_binding_8 PF13450.1 EIE75386.1 - 7.7e-05 22.6 0.0 0.00016 21.6 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DUF2357 PF09823.4 EIE75386.1 - 0.039 13.0 0.0 0.045 12.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2357) Lycopene_cycl PF05834.7 EIE75386.1 - 0.043 12.7 0.0 0.08 11.8 0.0 1.4 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_3 PF01494.14 EIE75386.1 - 0.062 12.3 0.0 0.094 11.7 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain FAD_binding_2 PF00890.19 EIE75386.1 - 0.15 10.9 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Bac_globin PF01152.16 EIE75387.1 - 0.093 12.7 0.3 0.093 12.7 0.2 2.9 3 0 0 3 3 3 0 Bacterial-like globin FUSC PF04632.7 EIE75387.1 - 9.1 4.5 5.4 15 3.8 3.7 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Peptidase_S10 PF00450.17 EIE75388.1 - 4.6e-29 101.8 0.0 1.4e-27 96.9 0.0 2.4 2 1 0 2 2 2 1 Serine carboxypeptidase Rhabdo_glycop PF00974.13 EIE75388.1 - 0.00061 18.1 0.0 0.00088 17.6 0.0 1.1 1 0 0 1 1 1 1 Rhabdovirus spike glycoprotein Abhydrolase_6 PF12697.2 EIE75388.1 - 0.0049 16.7 0.0 0.0072 16.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family GP41 PF00517.12 EIE75388.1 - 0.027 14.0 0.0 0.049 13.1 0.0 1.3 1 0 0 1 1 1 0 Retroviral envelope protein DUF912 PF06024.7 EIE75388.1 - 0.039 13.9 0.1 0.13 12.3 0.0 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) BatD PF13584.1 EIE75388.1 - 0.069 11.7 0.0 0.099 11.2 0.0 1.1 1 0 0 1 1 1 0 Oxygen tolerance Herpes_gE PF02480.11 EIE75388.1 - 0.074 11.2 0.6 0.11 10.7 0.0 1.5 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E Orthoreo_P10 PF07204.6 EIE75388.1 - 0.077 12.7 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 LST1 PF05083.8 EIE75388.1 - 0.19 11.7 1.4 5.8 6.9 0.1 2.6 2 0 0 2 2 2 0 LST-1 protein CDC45 PF02724.9 EIE75388.1 - 1.6 6.6 10.0 0.048 11.7 0.2 2.0 2 0 0 2 2 2 0 CDC45-like protein Ribosomal_60s PF00428.14 EIE75390.1 - 0.048 14.0 0.0 0.056 13.8 0.0 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein Peptidase_M1 PF01433.15 EIE75391.1 - 4.4e-64 216.9 0.1 1.5e-37 129.6 0.0 2.1 1 1 1 2 2 2 2 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 EIE75391.1 - 1e-43 148.3 0.2 1.7e-43 147.6 0.1 1.4 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 EIE75391.1 - 1.4e-14 54.2 0.0 2.5e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily F-box PF00646.28 EIE75393.1 - 6e-06 25.7 0.0 1.2e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EIE75393.1 - 0.00021 20.9 0.2 0.00057 19.5 0.1 1.7 1 0 0 1 1 1 1 F-box-like Elongin_A PF06881.6 EIE75393.1 - 0.00037 20.8 0.1 0.00075 19.8 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A ORC4_C PF14629.1 EIE75394.1 - 3.4e-34 118.0 0.0 6.6e-34 117.0 0.0 1.4 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.1 EIE75394.1 - 1.7e-18 67.3 0.5 7.8e-18 65.1 0.4 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 EIE75394.1 - 9.6e-10 38.7 0.0 1.9e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EIE75394.1 - 1.5e-07 31.3 0.0 3.2e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Archaeal ATPase AAA_22 PF13401.1 EIE75394.1 - 1.6e-07 31.4 0.0 3.3e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EIE75394.1 - 1.5e-06 27.9 0.4 7.6e-06 25.6 0.1 2.0 2 0 0 2 2 2 1 NACHT domain DUF815 PF05673.8 EIE75394.1 - 1.1e-05 24.4 0.0 1.8e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) KAP_NTPase PF07693.9 EIE75394.1 - 0.0093 14.9 0.0 0.022 13.7 0.0 1.5 1 1 0 1 1 1 1 KAP family P-loop domain Bac_DnaA PF00308.13 EIE75394.1 - 0.02 14.5 0.9 1.1 8.8 0.0 2.5 3 0 0 3 3 3 0 Bacterial dnaA protein PEPCK_ATP PF01293.15 EIE75394.1 - 0.036 12.5 0.0 0.065 11.7 0.0 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase AAA_14 PF13173.1 EIE75394.1 - 0.086 12.7 1.8 0.37 10.6 0.0 2.8 2 1 1 3 3 3 0 AAA domain Miro PF08477.8 EIE75394.1 - 0.097 13.1 0.0 0.31 11.5 0.0 1.9 1 1 0 1 1 1 0 Miro-like protein G-alpha PF00503.15 EIE75394.1 - 0.25 9.9 2.2 0.16 10.5 0.2 1.6 2 0 0 2 2 2 0 G-protein alpha subunit Abhydrolase_3 PF07859.8 EIE75395.1 - 5.9e-33 114.2 0.0 1.5e-25 90.0 0.0 2.4 1 1 1 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 EIE75395.1 - 8.1e-05 21.4 0.0 0.00014 20.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Med1 PF10744.4 EIE75396.1 - 5.2e-16 58.4 2.9 9.8e-16 57.4 2.0 1.6 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 Pkinase PF00069.20 EIE75397.1 - 3.4e-60 203.3 0.0 4e-60 203.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE75397.1 - 4.9e-23 81.5 0.0 7.3e-23 80.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE75397.1 - 2.9e-06 26.4 0.0 1.2e-05 24.4 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EIE75397.1 - 0.0042 16.8 0.0 0.0086 15.8 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EIE75397.1 - 0.0067 16.0 0.0 0.0099 15.4 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Rhamno_transf PF11316.3 EIE75398.1 - 0.062 12.5 0.0 0.065 12.4 0.0 1.0 1 0 0 1 1 1 0 Putative rhamnosyl transferase CotH PF08757.6 EIE75400.1 - 5e-43 147.5 8.3 6.9e-43 147.1 5.8 1.1 1 0 0 1 1 1 1 CotH protein EMP24_GP25L PF01105.19 EIE75402.1 - 1.1e-41 142.6 0.7 1.2e-41 142.4 0.5 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF1777 PF08648.7 EIE75403.1 - 0.00024 20.8 44.2 0.00035 20.3 30.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1777) ubiquitin PF00240.18 EIE75403.1 - 0.00045 19.5 0.1 0.0011 18.2 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 EIE75403.1 - 0.12 12.6 0.1 0.47 10.7 0.0 1.9 1 1 0 1 1 1 0 Ubiquitin-like domain PLRV_ORF5 PF01690.12 EIE75403.1 - 0.77 8.8 8.9 0.84 8.7 6.2 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Red1 PF07964.6 EIE75403.1 - 0.9 7.6 9.6 1.1 7.3 6.7 1.1 1 0 0 1 1 1 0 Rec10 / Red1 DUF566 PF04484.7 EIE75403.1 - 1.2 8.5 15.3 1.5 8.2 10.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) Hid1 PF12722.2 EIE75403.1 - 3.2 5.3 7.6 3.3 5.2 5.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Peptidase_M24 PF00557.19 EIE75404.1 - 7e-54 182.5 0.0 1.3e-53 181.7 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EIE75404.1 - 6.5e-36 122.6 0.0 1.1e-35 121.8 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain IFRD PF05004.8 EIE75404.1 - 2e-31 109.2 0.3 2.9e-31 108.7 0.2 1.2 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) CodY PF06018.9 EIE75404.1 - 0.045 13.0 0.0 0.43 9.8 0.0 2.3 2 0 0 2 2 2 0 CodY GAF-like domain HEAT PF02985.17 EIE75404.1 - 0.16 12.1 0.0 45 4.4 0.0 3.0 2 0 0 2 2 2 0 HEAT repeat Dus PF01207.12 EIE75405.1 - 9e-42 142.9 0.0 6.1e-24 84.3 0.0 2.4 1 1 1 2 2 2 2 Dihydrouridine synthase (Dus) Queuosine_synth PF02547.10 EIE75405.1 - 0.057 12.1 0.4 0.094 11.4 0.3 1.2 1 0 0 1 1 1 0 Queuosine biosynthesis protein zf-CCCH_2 PF14608.1 EIE75405.1 - 6.4 6.9 7.2 9.9 6.3 0.3 2.7 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type 5_nucleotid PF05761.9 EIE75406.1 - 4.3e-93 312.2 2.0 7.2e-93 311.5 1.4 1.3 1 1 0 1 1 1 1 5' nucleotidase family HAD_2 PF13419.1 EIE75406.1 - 0.00016 21.9 0.2 0.00091 19.4 0.0 2.2 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EIE75406.1 - 0.088 12.7 0.0 1.3 8.9 0.0 2.4 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Nucleoside_tran PF01733.13 EIE75407.1 - 6.6e-53 179.8 13.5 1.8e-51 175.1 9.4 2.1 1 1 0 1 1 1 1 Nucleoside transporter DUF1673 PF07895.6 EIE75407.1 - 5.2 6.5 9.6 0.097 12.1 0.8 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1673) Sigma_reg_N PF13800.1 EIE75407.1 - 5.6 7.0 8.6 6.8 6.7 0.0 4.3 5 0 0 5 5 5 0 Sigma factor regulator N-terminal DUF1467 PF07330.7 EIE75407.1 - 6 6.7 7.4 7 6.5 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1467) DSPc PF00782.15 EIE75409.1 - 1e-06 28.3 0.0 1.4e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EIE75409.1 - 7.4e-06 25.4 0.0 8.5e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase HLH PF00010.21 EIE75410.1 - 1.2e-12 47.2 0.1 1.2e-12 47.2 0.1 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain MFMR PF07777.6 EIE75410.1 - 0.015 15.2 9.5 0.044 13.6 6.6 1.8 1 0 0 1 1 1 0 G-box binding protein MFMR Mem_trans PF03547.13 EIE75410.1 - 2.7 6.1 4.3 4 5.6 3.0 1.3 1 0 0 1 1 1 0 Membrane transport protein CotH PF08757.6 EIE75411.1 - 3.5e-24 85.6 4.1 4.2e-24 85.3 2.9 1.0 1 0 0 1 1 1 1 CotH protein F-box-like PF12937.2 EIE75412.1 - 0.023 14.3 0.1 0.041 13.6 0.1 1.4 1 0 0 1 1 1 0 F-box-like HTH_9 PF08221.6 EIE75412.1 - 0.025 14.4 0.2 0.048 13.5 0.1 1.5 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain IMS PF00817.15 EIE75413.1 - 1.4e-30 106.0 0.1 2.3e-30 105.3 0.1 1.3 1 1 0 1 1 1 1 impB/mucB/samB family FAIM1 PF06905.8 EIE75413.1 - 0.057 12.5 0.2 0.073 12.2 0.2 1.2 1 0 0 1 1 1 0 Fas apoptotic inhibitory molecule (FAIM1) ACBP PF00887.14 EIE75414.1 - 9.3e-31 105.3 1.0 9.9e-31 105.2 0.7 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein FERM_M PF00373.13 EIE75414.1 - 0.004 17.3 0.3 0.021 14.9 0.1 1.8 2 0 0 2 2 2 1 FERM central domain Xan_ur_permease PF00860.15 EIE75415.1 - 2.9e-59 200.5 26.5 5.6e-58 196.2 18.3 2.0 1 1 0 1 1 1 1 Permease family MPC PF03650.8 EIE75415.1 - 0.077 12.9 0.7 0.35 10.7 0.1 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0041) ATP_sub_h PF10775.4 EIE75416.1 - 8.4e-18 63.8 2.3 1.3e-17 63.2 1.6 1.3 1 0 0 1 1 1 1 ATP synthase complex subunit h ATP-synt_F6 PF05511.6 EIE75416.1 - 0.013 15.4 0.2 0.017 14.9 0.1 1.4 1 1 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 HSP90 PF00183.13 EIE75417.1 - 5.5e-256 850.0 34.0 5.5e-256 850.0 23.6 1.5 2 0 0 2 2 2 1 Hsp90 protein HATPase_c PF02518.21 EIE75417.1 - 2.4e-12 46.5 0.0 4.3e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EIE75417.1 - 3.6e-11 42.8 0.2 3.6e-11 42.8 0.1 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF399 PF04187.8 EIE75417.1 - 0.037 13.5 2.3 0.1 12.0 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function, DUF399 ATP_bind_4 PF01902.12 EIE75417.1 - 0.28 10.4 7.5 0.086 12.1 1.0 2.4 2 0 0 2 2 2 0 ATP-binding region Kelch_6 PF13964.1 EIE75418.1 - 3.8e-26 90.1 1.5 2.7e-06 27.3 0.0 5.4 4 1 1 5 5 5 5 Kelch motif Kelch_5 PF13854.1 EIE75418.1 - 1.6e-25 88.5 1.4 4.7e-06 26.4 0.0 5.2 5 0 0 5 5 5 4 Kelch motif Kelch_4 PF13418.1 EIE75418.1 - 7.8e-25 86.3 4.9 1.5e-09 37.4 0.1 5.9 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.1 EIE75418.1 - 3.8e-19 68.3 0.1 0.00019 21.5 0.0 5.4 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_2 PF07646.10 EIE75418.1 - 3.9e-19 67.6 4.0 9.7e-05 21.9 0.0 5.0 6 0 0 6 6 6 4 Kelch motif Kelch_1 PF01344.20 EIE75418.1 - 1.1e-15 56.8 1.6 0.0053 16.2 0.1 4.5 4 0 0 4 4 4 4 Kelch motif Rax2 PF12768.2 EIE75418.1 - 0.0031 16.7 0.0 0.41 9.8 0.0 2.1 1 1 1 2 2 2 2 Cortical protein marker for cell polarity Ribosomal_L37ae PF01780.14 EIE75419.1 - 9.3e-41 137.6 10.8 1e-40 137.4 7.5 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.2 EIE75419.1 - 0.00069 19.3 2.2 0.001 18.8 1.5 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain A2L_zn_ribbon PF08792.5 EIE75419.1 - 0.0047 16.3 3.3 0.84 9.1 0.1 2.2 2 0 0 2 2 2 2 A2L zinc ribbon domain zf-FCS PF06467.9 EIE75419.1 - 0.027 14.0 2.2 0.75 9.4 0.1 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-H2C2_2 PF13465.1 EIE75419.1 - 0.08 13.2 1.4 2.5 8.5 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger double domain zf-BED PF02892.10 EIE75419.1 - 0.1 12.3 5.5 0.12 12.1 0.4 2.3 1 1 1 2 2 2 0 BED zinc finger Zn-ribbon_8 PF09723.5 EIE75419.1 - 0.17 11.8 1.7 0.9 9.5 0.1 2.2 2 0 0 2 2 2 0 Zinc ribbon domain Elf1 PF05129.8 EIE75419.1 - 0.27 10.9 2.7 0.5 10.0 1.9 1.5 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like zf-C2H2 PF00096.21 EIE75419.1 - 1.8 9.0 4.1 18 5.8 0.3 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type RGS PF00615.14 EIE75420.1 - 0.0073 16.3 0.3 0.011 15.7 0.2 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain ABC2_membrane_5 PF13346.1 EIE75420.1 - 0.34 10.1 9.5 0.59 9.3 6.6 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein Tic20 PF09685.5 EIE75420.1 - 1 9.3 6.3 2.1 8.3 4.4 1.4 1 0 0 1 1 1 0 Tic20-like protein Amidase PF01425.16 EIE75421.1 - 5.1e-70 236.5 0.0 6.2e-70 236.2 0.0 1.1 1 0 0 1 1 1 1 Amidase PHD PF00628.24 EIE75422.1 - 6e-10 38.6 8.8 8.3e-10 38.2 6.1 1.2 1 0 0 1 1 1 1 PHD-finger zf-U1 PF06220.7 EIE75422.1 - 0.069 12.7 0.9 0.069 12.7 0.7 1.8 2 0 0 2 2 2 0 U1 zinc finger zf-HC5HC2H PF13771.1 EIE75422.1 - 0.1 12.7 5.8 0.28 11.3 4.0 1.7 1 1 1 2 2 2 0 PHD-like zinc-binding domain PHD_2 PF13831.1 EIE75422.1 - 1.8 7.9 12.0 0.081 12.2 4.3 1.8 2 1 0 2 2 2 0 PHD-finger Glyco_hydro_15 PF00723.16 EIE75423.1 - 1.2e-70 238.3 0.0 1.5e-70 237.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 RNase_T PF00929.19 EIE75424.1 - 3.7e-10 40.3 0.1 1.1e-09 38.8 0.0 1.7 2 1 0 2 2 2 1 Exonuclease Phage_integrase PF00589.17 EIE75427.1 - 6e-05 22.7 0.0 8.2e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family DUF3997 PF13162.1 EIE75428.1 - 0.085 12.6 1.4 0.17 11.6 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3997) RVT_1 PF00078.22 EIE75430.1 - 8.1e-10 38.4 0.0 9.5e-10 38.1 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Terminase_GpA PF05876.7 EIE75431.1 - 0.026 12.8 0.1 0.038 12.3 0.1 1.2 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) HAUS4 PF14735.1 EIE75431.1 - 0.13 11.5 0.0 0.13 11.5 0.0 2.3 3 0 0 3 3 3 0 HAUS augmin-like complex subunit 4 DDE_3 PF13358.1 EIE75432.1 - 3.8e-06 26.7 0.0 4.4e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4043 PF13252.1 EIE75432.1 - 0.12 11.2 0.1 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4043) RVT_1 PF00078.22 EIE75433.1 - 2.1e-14 53.4 0.0 2.5e-14 53.1 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.18 EIE75436.1 - 4e-05 23.3 14.7 0.0026 17.6 0.4 2.3 2 0 0 2 2 2 2 Zinc knuckle Cytochrome_C554 PF13435.1 EIE75436.1 - 0.019 14.9 0.7 0.019 14.9 0.5 1.8 2 0 0 2 2 2 0 Cytochrome c554 and c-prime zf-CCHC_4 PF14392.1 EIE75436.1 - 0.14 11.8 6.1 1.1 8.9 0.4 2.5 2 0 0 2 2 2 0 Zinc knuckle zf-nanos PF05741.8 EIE75436.1 - 0.31 11.0 4.9 0.78 9.7 3.4 1.7 1 0 0 1 1 1 0 Nanos RNA binding domain DDE_3 PF13358.1 EIE75437.1 - 4.1e-28 97.9 0.0 7.8e-28 97.0 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_1 PF01527.15 EIE75437.1 - 0.00012 21.9 0.3 0.0003 20.6 0.2 1.6 1 0 0 1 1 1 1 Transposase DDE_Tnp_ISAZ013 PF07592.6 EIE75437.1 - 0.0011 17.8 1.3 0.35 9.5 0.0 2.5 2 1 1 3 3 3 2 Rhodopirellula transposase DDE domain YniB PF14002.1 EIE75437.1 - 0.0025 17.2 0.0 0.26 10.7 0.0 2.2 2 0 0 2 2 2 1 YniB-like protein HTH_32 PF13565.1 EIE75437.1 - 0.0094 16.7 0.0 0.024 15.4 0.0 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.1 EIE75437.1 - 0.02 14.8 0.1 0.05 13.6 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain CP12 PF02672.10 EIE75437.1 - 0.027 14.9 1.2 0.068 13.6 0.8 1.6 1 0 0 1 1 1 0 CP12 domain FAM219A PF15260.1 EIE75437.1 - 0.03 14.6 0.5 0.051 13.9 0.4 1.3 1 0 0 1 1 1 0 Protein family FAM219A HTH_psq PF05225.11 EIE75437.1 - 0.11 12.0 0.3 0.51 9.9 0.0 2.1 3 0 0 3 3 3 0 helix-turn-helix, Psq domain HTH_WhiA PF02650.9 EIE75437.1 - 0.21 12.0 2.9 3.5 8.0 1.6 2.6 1 1 0 1 1 1 0 WhiA C-terminal HTH domain zf-CCHC PF00098.18 EIE75438.1 - 6.2e-05 22.7 14.7 0.0032 17.3 0.4 2.3 2 0 0 2 2 2 2 Zinc knuckle Cytochrome_C554 PF13435.1 EIE75438.1 - 0.026 14.5 0.7 0.026 14.5 0.5 1.9 2 0 0 2 2 2 0 Cytochrome c554 and c-prime zf-CCHC_4 PF14392.1 EIE75438.1 - 0.2 11.3 6.1 1.4 8.6 0.4 2.6 2 0 0 2 2 2 0 Zinc knuckle zf-nanos PF05741.8 EIE75438.1 - 0.39 10.7 4.9 1 9.4 3.4 1.7 1 0 0 1 1 1 0 Nanos RNA binding domain RVT_1 PF00078.22 EIE75441.1 - 2.1e-14 53.4 0.0 2.5e-14 53.1 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_3 PF13358.1 EIE75442.1 - 1.4e-13 50.7 0.0 1.6e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EIE75443.1 - 3.8e-06 26.7 0.0 4.4e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4043 PF13252.1 EIE75443.1 - 0.12 11.2 0.1 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4043) Terminase_GpA PF05876.7 EIE75444.1 - 0.026 12.8 0.1 0.038 12.3 0.1 1.2 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) HAUS4 PF14735.1 EIE75444.1 - 0.31 10.2 0.0 0.31 10.2 0.0 2.3 3 0 0 3 3 3 0 HAUS augmin-like complex subunit 4 RVT_1 PF00078.22 EIE75445.1 - 6.3e-10 38.7 0.0 7.5e-10 38.5 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3997 PF13162.1 EIE75447.1 - 0.085 12.6 1.4 0.17 11.6 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3997) Fasciclin PF02469.17 EIE75449.1 - 2e-25 89.2 14.2 8.3e-17 61.3 0.7 2.6 2 1 0 2 2 2 2 Fasciclin domain GMC_oxred_N PF00732.14 EIE75450.1 - 1.2e-55 188.7 0.1 1.6e-55 188.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EIE75450.1 - 5e-12 45.3 0.7 8.7e-06 24.8 0.4 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EIE75450.1 - 2.8e-09 36.3 7.0 3.8e-08 32.6 4.8 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EIE75450.1 - 3.2e-05 23.8 0.8 0.018 14.9 0.3 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIE75450.1 - 0.00011 20.7 4.8 0.0073 14.8 0.7 2.5 3 0 0 3 3 3 2 HI0933-like protein GDI PF00996.13 EIE75450.1 - 0.00063 18.1 0.1 0.0013 17.1 0.1 1.4 1 0 0 1 1 1 1 GDP dissociation inhibitor FAD_binding_3 PF01494.14 EIE75450.1 - 0.0011 18.1 0.3 0.003 16.6 0.4 1.6 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 EIE75450.1 - 0.0032 17.4 4.2 0.016 15.2 1.6 2.9 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain ApbA PF02558.11 EIE75450.1 - 0.0081 15.6 0.1 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.7 EIE75450.1 - 0.017 14.0 0.2 0.29 9.9 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.12 EIE75450.1 - 0.039 13.0 0.5 0.093 11.8 0.1 1.7 2 0 0 2 2 2 0 Thi4 family DUF3500 PF12006.3 EIE75450.1 - 0.04 12.8 0.1 0.069 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3500) GIDA PF01134.17 EIE75450.1 - 0.047 12.5 0.2 0.28 10.0 0.1 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox PF00070.22 EIE75450.1 - 0.068 13.5 1.0 0.57 10.6 0.1 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EIE75450.1 - 0.29 10.1 1.6 1.7 7.6 1.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase FHA PF00498.21 EIE75451.1 - 0.00084 19.4 0.5 0.0027 17.7 0.3 2.0 1 0 0 1 1 1 1 FHA domain Fork_head PF00250.13 EIE75451.1 - 0.0017 18.3 0.0 0.0045 16.9 0.0 1.8 1 1 0 1 1 1 1 Fork head domain SAE2 PF08573.5 EIE75451.1 - 0.25 12.0 4.2 8.3 7.1 0.0 2.5 2 0 0 2 2 2 0 DNA repair protein endonuclease SAE2/CtIP C-terminus Ras PF00071.17 EIE75453.1 - 3.2e-33 114.4 0.2 1.5e-16 60.1 0.0 2.0 1 1 1 2 2 2 2 Ras family Miro PF08477.8 EIE75453.1 - 5.5e-08 33.3 0.2 3.3e-06 27.6 0.0 2.3 1 1 1 2 2 2 1 Miro-like protein FeoB_N PF02421.13 EIE75453.1 - 5.9e-06 25.6 0.0 0.024 13.9 0.0 2.1 1 1 1 2 2 2 2 Ferrous iron transport protein B MMR_HSR1 PF01926.18 EIE75453.1 - 2e-05 24.4 0.0 2.6e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.16 EIE75453.1 - 6.3e-05 22.2 0.0 0.0025 17.0 0.0 2.1 1 1 1 2 2 2 2 ADP-ribosylation factor family GTP_EFTU PF00009.22 EIE75453.1 - 0.00074 18.9 0.1 0.013 14.9 0.0 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Arch_ATPase PF01637.13 EIE75453.1 - 0.0009 19.0 0.1 0.0016 18.2 0.1 1.4 1 1 0 1 1 1 1 Archaeal ATPase AAA_14 PF13173.1 EIE75453.1 - 0.0029 17.4 0.0 0.004 17.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain ArgK PF03308.11 EIE75453.1 - 0.024 13.4 0.0 0.43 9.3 0.0 2.1 2 0 0 2 2 2 0 ArgK protein SRPRB PF09439.5 EIE75453.1 - 0.059 12.5 0.0 0.12 11.6 0.0 1.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit DWNN PF08783.6 EIE75454.1 - 0.044 13.7 0.1 0.055 13.4 0.0 1.2 1 0 0 1 1 1 0 DWNN domain DDE_3 PF13358.1 EIE75456.1 - 3.3e-24 85.3 0.0 3.8e-24 85.1 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE75456.1 - 0.035 14.2 0.0 0.053 13.6 0.0 1.4 1 0 0 1 1 1 0 Integrase core domain DUF676 PF05057.9 EIE75457.1 - 7.6e-08 31.9 0.0 9.9e-08 31.5 0.0 1.1 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 EIE75457.1 - 2.6e-06 27.2 0.0 4.1e-06 26.5 0.0 1.4 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EIE75457.1 - 7.6e-06 25.7 0.7 0.00018 21.3 0.5 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIE75457.1 - 2.8e-05 24.0 0.1 0.0002 21.3 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.7 EIE75457.1 - 9.2e-05 21.8 0.1 0.00026 20.3 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Lipase_3 PF01764.20 EIE75457.1 - 0.00018 21.1 0.0 0.0003 20.4 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) DUF915 PF06028.6 EIE75457.1 - 0.0095 15.0 0.0 0.021 13.8 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) DUF2305 PF10230.4 EIE75457.1 - 0.012 15.0 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Thioesterase PF00975.15 EIE75457.1 - 0.022 14.9 0.0 0.08 13.1 0.0 1.9 2 0 0 2 2 2 0 Thioesterase domain LCAT PF02450.10 EIE75457.1 - 0.14 11.0 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Miro PF08477.8 EIE75458.1 - 0.00025 21.5 0.0 0.00071 20.0 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 EIE75458.1 - 0.0069 15.7 0.2 0.18 11.1 0.2 2.8 1 1 1 2 2 2 1 Ras family DUF4604 PF15377.1 EIE75458.1 - 0.011 16.0 5.2 0.011 16.0 3.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) DRY_EERY PF09750.4 EIE75458.1 - 3.2 7.8 8.7 9.5 6.3 5.8 2.1 1 1 0 1 1 1 0 Alternative splicing regulator zf-C3HC4 PF00097.20 EIE75459.1 - 5.2e-11 42.0 7.9 8e-11 41.4 5.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIE75459.1 - 1e-10 41.2 9.6 1.6e-10 40.6 6.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EIE75459.1 - 3.4e-10 39.7 8.9 5.3e-10 39.1 6.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIE75459.1 - 2e-08 33.8 7.0 3.1e-08 33.2 4.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EIE75459.1 - 8.3e-08 31.7 7.7 1.2e-07 31.2 5.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Baculo_IE-1 PF05290.6 EIE75459.1 - 7.4e-07 28.9 2.9 9.9e-07 28.5 2.0 1.2 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-C3HC4_4 PF15227.1 EIE75459.1 - 2.4e-06 27.2 8.3 4e-06 26.6 5.7 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EIE75459.1 - 1.8e-05 24.3 1.7 1.8e-05 24.3 1.2 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.2 EIE75459.1 - 7.5e-05 22.7 4.8 0.00013 22.0 3.3 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EIE75459.1 - 0.0014 18.4 4.7 0.0022 17.7 3.2 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.1 EIE75459.1 - 0.057 13.1 3.7 0.11 12.3 2.6 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-MIZ PF02891.15 EIE75459.1 - 0.081 12.4 7.4 0.13 11.7 5.1 1.3 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_4 PF14570.1 EIE75459.1 - 0.35 10.5 7.3 1.7 8.3 5.1 2.0 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-CHY PF05495.7 EIE75459.1 - 0.96 9.6 6.7 1.5 9.0 4.7 1.3 1 0 0 1 1 1 0 CHY zinc finger IBR PF01485.16 EIE75459.1 - 5.6 6.9 11.4 2.1 8.2 5.2 2.2 1 1 1 2 2 2 0 IBR domain RhoGEF PF00621.15 EIE75460.1 - 6.6e-41 140.1 4.7 6.6e-41 140.1 3.2 2.7 3 0 0 3 3 3 1 RhoGEF domain SH3_9 PF14604.1 EIE75460.1 - 1.9e-16 59.3 1.7 3.9e-09 35.9 0.0 3.0 3 0 0 3 3 3 2 Variant SH3 domain SH3_1 PF00018.23 EIE75460.1 - 5.9e-16 57.5 1.3 5.3e-11 41.7 0.0 2.8 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 EIE75460.1 - 2.5e-12 46.1 0.1 2.4e-07 30.1 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain UPF0220 PF05255.6 EIE75462.1 - 2.3e-50 170.1 1.7 2.7e-50 169.8 1.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) RasGAP PF00616.14 EIE75463.1 - 1.2e-55 188.2 0.2 1.2e-55 188.2 0.1 2.8 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 EIE75463.1 - 2.5e-31 108.2 3.6 2.5e-31 108.2 2.5 2.3 2 0 0 2 2 2 1 RasGAP C-terminus DUF2187 PF09953.4 EIE75463.1 - 2.4 7.9 5.3 0.47 10.2 0.4 2.3 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2187) SH3_9 PF14604.1 EIE75464.1 - 5.1e-31 106.0 1.0 2.7e-14 52.4 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 EIE75464.1 - 2.1e-26 91.0 6.5 3.8e-13 48.5 0.1 2.9 3 0 0 3 3 3 2 SH3 domain SH3_2 PF07653.12 EIE75464.1 - 1.8e-19 68.9 0.0 2.1e-09 36.7 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain Cofilin_ADF PF00241.15 EIE75464.1 - 9.9e-14 51.3 0.2 6e-13 48.7 0.0 2.1 2 0 0 2 2 2 1 Cofilin/tropomyosin-type actin-binding protein MIP-T3 PF10243.4 EIE75464.1 - 0.00011 20.8 52.5 0.00015 20.3 36.4 1.2 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Med15 PF09606.5 EIE75464.1 - 5.3 5.1 44.7 7.1 4.6 31.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal SAC3_GANP PF03399.11 EIE75465.1 - 5.6e-65 218.7 2.6 5.6e-65 218.7 1.8 1.5 2 0 0 2 2 2 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EIE75465.1 - 1.5e-05 24.7 1.0 7.8e-05 22.4 0.0 2.1 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 PSS PF03034.10 EIE75466.1 - 3.6e-94 315.2 12.4 3.6e-94 315.2 8.6 2.3 2 0 0 2 2 2 1 Phosphatidyl serine synthase ABC_tran PF00005.22 EIE75466.1 - 6.8e-53 178.6 0.0 1.5e-29 103.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EIE75466.1 - 8e-53 179.6 34.4 2.1e-27 96.2 7.9 3.2 3 1 0 3 3 2 2 ABC transporter transmembrane region SMC_N PF02463.14 EIE75466.1 - 2.9e-11 43.0 0.6 9.9e-05 21.6 0.0 4.2 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EIE75466.1 - 2.1e-08 34.7 0.8 3.1e-05 24.4 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.1 EIE75466.1 - 2e-06 27.3 0.0 0.017 14.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 EIE75466.1 - 2.4e-06 26.6 0.0 0.017 14.0 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.1 EIE75466.1 - 2.8e-06 26.7 0.2 0.074 12.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EIE75466.1 - 6.9e-06 26.8 0.0 0.25 12.1 0.0 3.1 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.12 EIE75466.1 - 2e-05 24.5 0.5 0.04 13.7 0.0 2.9 3 0 0 3 3 3 2 Domain of unknown function DUF87 AAA_21 PF13304.1 EIE75466.1 - 2.9e-05 24.1 7.5 0.15 12.0 0.1 4.4 4 1 0 4 4 2 2 AAA domain AAA_18 PF13238.1 EIE75466.1 - 3.2e-05 24.2 0.1 0.57 10.4 0.0 3.3 3 0 0 3 3 2 2 AAA domain Miro PF08477.8 EIE75466.1 - 3.7e-05 24.1 0.0 0.066 13.7 0.0 2.9 2 1 0 2 2 2 1 Miro-like protein AAA_10 PF12846.2 EIE75466.1 - 8e-05 22.2 0.1 0.2 11.0 0.1 2.5 2 0 0 2 2 2 2 AAA-like domain MobB PF03205.9 EIE75466.1 - 0.00019 21.1 0.5 0.38 10.4 0.1 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 EIE75466.1 - 0.0002 20.5 0.0 0.02 14.0 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 IstB_IS21 PF01695.12 EIE75466.1 - 0.00036 19.9 0.0 0.55 9.6 0.0 3.3 3 0 0 3 3 3 1 IstB-like ATP binding protein ResIII PF04851.10 EIE75466.1 - 0.00038 20.3 0.0 0.2 11.4 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EIE75466.1 - 0.00067 19.8 4.2 0.1 12.7 0.1 3.3 2 1 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 EIE75466.1 - 0.00083 18.8 0.0 1.1 8.6 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 EIE75466.1 - 0.00096 19.0 0.8 0.56 10.1 0.1 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_14 PF13173.1 EIE75466.1 - 0.0016 18.3 0.2 0.63 9.9 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 EIE75466.1 - 0.0018 17.9 0.8 0.02 14.6 0.2 2.7 2 0 0 2 2 2 1 Part of AAA domain NACHT PF05729.7 EIE75466.1 - 0.0024 17.5 0.9 0.32 10.6 0.1 2.7 2 0 0 2 2 2 1 NACHT domain SbcCD_C PF13558.1 EIE75466.1 - 0.005 16.7 0.3 8.9 6.3 0.0 3.4 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit Pox_A32 PF04665.7 EIE75466.1 - 0.0068 15.7 0.2 4.3 6.5 0.0 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_33 PF13671.1 EIE75466.1 - 0.0073 16.1 5.4 0.15 11.9 0.1 3.2 3 1 0 3 3 2 1 AAA domain Zeta_toxin PF06414.7 EIE75466.1 - 0.0079 15.3 0.0 1 8.4 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin Dynamin_N PF00350.18 EIE75466.1 - 0.016 15.0 0.3 1.1 9.1 0.0 2.5 2 0 0 2 2 2 0 Dynamin family AAA_24 PF13479.1 EIE75466.1 - 0.017 14.7 0.3 0.5 9.9 0.1 2.4 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 EIE75466.1 - 0.019 14.4 2.3 0.14 11.5 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.24 EIE75466.1 - 0.029 14.5 0.2 4.5 7.4 0.0 3.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 EIE75466.1 - 0.03 13.1 2.9 0.79 8.5 0.0 3.3 4 0 0 4 4 4 0 NB-ARC domain AAA_16 PF13191.1 EIE75466.1 - 0.043 13.8 4.3 1.1 9.1 0.1 2.8 2 1 0 2 2 2 0 AAA ATPase domain TrwB_AAD_bind PF10412.4 EIE75466.1 - 0.051 12.1 0.1 7.6 5.0 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_30 PF13604.1 EIE75466.1 - 0.076 12.5 0.2 3.5 7.1 0.1 2.9 3 0 0 3 3 3 0 AAA domain Arch_ATPase PF01637.13 EIE75466.1 - 0.079 12.6 0.5 0.93 9.1 0.0 2.7 3 0 0 3 3 2 0 Archaeal ATPase ATP_bind_1 PF03029.12 EIE75466.1 - 0.082 12.4 1.6 9.6 5.6 0.2 3.2 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein ArgK PF03308.11 EIE75466.1 - 0.12 11.0 0.0 0.56 8.9 0.0 1.9 2 0 0 2 2 2 0 ArgK protein SRP54 PF00448.17 EIE75466.1 - 0.18 11.2 0.1 3.9 6.8 0.1 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain PhoH PF02562.11 EIE75466.1 - 0.19 10.9 0.5 8.1 5.6 0.0 2.7 3 0 0 3 3 3 0 PhoH-like protein RNA_helicase PF00910.17 EIE75466.1 - 0.24 11.5 2.3 13 5.9 0.0 3.1 4 0 0 4 4 2 0 RNA helicase ABC_ATPase PF09818.4 EIE75466.1 - 1.2 7.6 1.8 6.5 5.2 0.0 2.5 3 0 0 3 3 3 0 Predicted ATPase of the ABC class ER_lumen_recept PF00810.13 EIE75468.1 - 0.065 13.7 3.7 0.18 12.2 2.0 1.9 1 1 1 2 2 2 0 ER lumen protein retaining receptor RAP1 PF07218.6 EIE75468.1 - 0.56 8.2 2.4 0.76 7.8 1.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) LSM PF01423.17 EIE75469.1 - 8.3e-17 60.5 0.1 1.1e-16 60.1 0.1 1.1 1 0 0 1 1 1 1 LSM domain Ribosomal_L5_C PF00673.16 EIE75470.1 - 1.7e-23 82.1 0.0 2.4e-23 81.6 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 EIE75470.1 - 1.8e-19 69.2 0.1 5.7e-19 67.6 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L5 Sugar_tr PF00083.19 EIE75471.1 - 9.8e-104 347.4 23.5 5.4e-53 180.1 4.6 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EIE75471.1 - 1.3e-23 83.3 36.2 2.1e-18 66.1 4.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.20 EIE75472.1 - 5.9e-54 182.9 0.0 7.5e-54 182.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE75472.1 - 1.2e-28 99.9 0.0 1.6e-28 99.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIE75472.1 - 0.00049 19.9 0.0 0.0008 19.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EIE75472.1 - 0.001 17.9 0.0 0.0017 17.2 0.0 1.3 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Chorismate_bind PF00425.13 EIE75473.1 - 2.3e-94 315.5 0.0 4.7e-94 314.5 0.0 1.5 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 EIE75473.1 - 1.7e-30 105.8 0.0 2.2e-29 102.2 0.0 2.5 3 0 0 3 3 3 1 Anthranilate synthase component I, N terminal region Dzip-like_N PF13815.1 EIE75473.1 - 0.24 11.1 1.9 0.29 10.9 0.0 2.0 2 0 0 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal Arrestin_N PF00339.24 EIE75474.1 - 5.2e-08 32.8 0.0 4.3e-07 29.8 0.0 2.5 3 1 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain CBM_25 PF03423.8 EIE75474.1 - 0.027 14.5 0.0 0.15 12.1 0.0 2.1 2 0 0 2 2 2 0 Carbohydrate binding domain (family 25) Ras PF00071.17 EIE75475.1 - 4.2e-59 198.5 0.1 4.9e-59 198.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIE75475.1 - 3.1e-19 69.6 0.0 4.6e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIE75475.1 - 1.5e-12 47.0 0.0 1.7e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EIE75475.1 - 1.8e-05 24.6 0.0 3.5e-05 23.7 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EIE75475.1 - 1.9e-05 23.9 0.0 2.4e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EIE75475.1 - 0.00011 21.7 0.0 0.00023 20.6 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Big_3_2 PF12245.3 EIE75475.1 - 0.0062 16.0 0.1 1.5 8.4 0.0 2.4 2 0 0 2 2 2 1 Bacterial Ig-like domain (group 3) SRPRB PF09439.5 EIE75475.1 - 0.0077 15.4 0.0 0.017 14.3 0.0 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 EIE75475.1 - 0.02 15.0 0.0 0.11 12.6 0.0 2.2 1 1 1 2 2 2 0 AAA domain DUF258 PF03193.11 EIE75475.1 - 0.022 13.9 0.1 0.093 11.9 0.0 1.9 2 1 0 3 3 3 0 Protein of unknown function, DUF258 AAA_14 PF13173.1 EIE75475.1 - 0.024 14.5 0.0 0.044 13.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EIE75475.1 - 0.031 14.2 0.1 0.058 13.3 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain G-alpha PF00503.15 EIE75475.1 - 0.11 11.2 0.1 2 6.9 0.0 2.1 1 1 1 2 2 2 0 G-protein alpha subunit GDA1_CD39 PF01150.12 EIE75476.1 - 2.4e-111 372.3 0.0 3.4e-111 371.8 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Colicin PF01024.14 EIE75476.1 - 0.2 11.2 0.0 0.33 10.4 0.0 1.2 1 0 0 1 1 1 0 Colicin pore forming domain DUF914 PF06027.7 EIE75477.1 - 0.048 12.4 0.7 0.048 12.5 0.5 1.0 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 EIE75477.1 - 0.19 11.7 8.1 0.27 11.2 5.6 1.3 1 0 0 1 1 1 0 EamA-like transporter family FUSC-like PF12805.2 EIE75477.1 - 1.7 7.4 4.6 8.7 5.1 0.0 2.0 2 0 0 2 2 2 0 FUSC-like inner membrane protein yccS Epimerase PF01370.16 EIE75478.1 - 2.1e-38 132.0 0.0 2.8e-38 131.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EIE75478.1 - 5.1e-13 48.5 0.0 1.6e-12 46.8 0.0 1.7 1 1 1 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.12 EIE75478.1 - 3.3e-11 42.6 0.0 4.3e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 EIE75478.1 - 3.8e-10 38.9 0.0 5.4e-10 38.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EIE75478.1 - 2.5e-07 29.8 0.0 6.4e-06 25.2 0.0 2.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein KAT11 PF08214.6 EIE75479.1 - 9.6e-38 130.1 3.0 1.2e-37 129.7 2.1 1.0 1 0 0 1 1 1 1 Histone acetylation protein DUF2360 PF10152.4 EIE75481.1 - 0.42 10.8 2.0 0.58 10.4 1.4 1.2 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Peptidase_C12 PF01088.16 EIE75482.1 - 1.2e-70 236.9 0.0 1.9e-70 236.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 OPT PF03169.10 EIE75483.1 - 8.8e-157 523.2 52.3 1e-156 523.0 36.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Toxin_trans PF07952.7 EIE75483.1 - 0.015 14.2 0.2 0.085 11.7 0.0 2.2 2 0 0 2 2 2 0 Clostridium neurotoxin, Translocation domain DUF2407_C PF13373.1 EIE75483.1 - 0.021 14.7 0.1 7.2 6.5 0.0 2.7 2 0 0 2 2 2 0 DUF2407 C-terminal domain Vac7 PF12751.2 EIE75485.1 - 2.1e-09 36.7 0.0 2.1e-09 36.7 0.0 1.7 2 0 0 2 2 2 1 Vacuolar segregation subunit 7 Pkinase PF00069.20 EIE75486.1 - 3e-41 141.2 0.0 4.1e-41 140.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE75486.1 - 3.1e-22 78.8 0.0 4.1e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EIE75486.1 - 1.1e-05 24.6 0.2 1.1e-05 24.6 0.1 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EIE75486.1 - 0.016 14.5 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Pyr_redox_2 PF07992.9 EIE75487.1 - 6.6e-07 29.4 0.0 2.3e-05 24.3 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EIE75487.1 - 5.6e-05 23.2 0.0 0.04 13.9 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EIE75487.1 - 0.00099 18.9 0.0 0.003 17.3 0.0 1.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EIE75487.1 - 0.0037 17.2 0.0 0.0083 16.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain OB_NTP_bind PF07717.11 EIE75488.1 - 6.3e-25 87.2 0.0 2.1e-24 85.5 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EIE75488.1 - 7.6e-24 83.6 0.0 5e-23 81.0 0.0 2.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EIE75488.1 - 5.5e-13 48.5 0.0 1.7e-12 46.9 0.0 1.8 2 0 0 2 2 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EIE75488.1 - 5.1e-09 35.8 0.1 1.9e-08 34.0 0.1 1.9 2 0 0 2 2 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EIE75488.1 - 1.2e-07 31.9 0.1 3.8e-07 30.3 0.1 1.9 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EIE75488.1 - 0.0011 18.5 0.0 0.0023 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.9 EIE75488.1 - 0.0017 18.1 0.1 0.0032 17.2 0.1 1.4 1 0 0 1 1 1 1 Flavivirus DEAD domain ResIII PF04851.10 EIE75488.1 - 0.0023 17.8 4.3 1.6 8.5 0.0 3.7 3 1 0 3 3 3 2 Type III restriction enzyme, res subunit AAA_10 PF12846.2 EIE75488.1 - 0.0026 17.2 0.2 1.5 8.2 0.1 2.5 1 1 0 2 2 2 2 AAA-like domain SRP54 PF00448.17 EIE75488.1 - 0.0026 17.2 0.5 0.0074 15.7 0.3 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain Sigma54_activ_2 PF14532.1 EIE75488.1 - 0.0027 17.7 0.0 0.01 15.8 0.0 2.0 1 0 0 1 1 1 1 Sigma-54 interaction domain NB-ARC PF00931.17 EIE75488.1 - 0.003 16.4 0.0 0.0073 15.1 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain AAA_14 PF13173.1 EIE75488.1 - 0.0033 17.3 0.2 0.041 13.7 0.2 2.6 1 1 0 1 1 1 1 AAA domain T2SE PF00437.15 EIE75488.1 - 0.0046 15.9 0.0 0.0092 14.9 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.22 EIE75488.1 - 0.009 16.3 3.1 0.033 14.4 0.0 2.9 3 0 0 3 3 3 1 ABC transporter Arch_ATPase PF01637.13 EIE75488.1 - 0.016 14.8 0.0 0.056 13.1 0.0 1.9 1 0 0 1 1 1 0 Archaeal ATPase Sigma54_activat PF00158.21 EIE75488.1 - 0.031 13.7 0.0 0.076 12.4 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_16 PF13191.1 EIE75488.1 - 0.041 13.8 0.0 0.12 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.1 EIE75488.1 - 0.046 13.4 0.0 0.15 11.8 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain NACHT PF05729.7 EIE75488.1 - 0.064 12.9 0.1 0.59 9.7 0.0 2.2 2 0 0 2 2 2 0 NACHT domain AAA_23 PF13476.1 EIE75488.1 - 0.073 13.3 0.0 0.073 13.3 0.0 3.1 3 0 0 3 3 2 0 AAA domain cobW PF02492.14 EIE75488.1 - 0.094 12.1 0.1 0.63 9.4 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 EIE75488.1 - 0.097 12.2 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 EIE75488.1 - 0.41 10.9 0.0 0.41 10.9 0.0 3.1 3 0 0 3 3 1 0 AAA domain HECT PF00632.20 EIE75489.1 - 1.2e-94 317.1 0.0 1.8e-94 316.4 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 EIE75489.1 - 1.3e-35 120.7 18.2 3.1e-12 46.1 0.3 3.8 3 0 0 3 3 3 3 WW domain C2 PF00168.25 EIE75489.1 - 2.1e-15 56.2 2.0 3.1e-15 55.7 0.4 2.1 2 0 0 2 2 2 1 C2 domain SSP160 PF06933.6 EIE75489.1 - 0.69 7.8 5.4 1.1 7.1 3.8 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Porin_3 PF01459.17 EIE75490.1 - 2.6e-48 164.7 0.6 2.9e-48 164.5 0.4 1.0 1 0 0 1 1 1 1 Eukaryotic porin Pab87_oct PF13969.1 EIE75490.1 - 0.11 12.5 0.3 0.24 11.5 0.2 1.6 1 1 0 1 1 1 0 Pab87 octamerisation domain tRNA-synt_2 PF00152.15 EIE75491.1 - 1.6e-79 267.1 0.1 2.3e-79 266.6 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EIE75491.1 - 3.3e-11 42.8 0.1 6.4e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Sugarporin_N PF11471.3 EIE75491.1 - 0.19 11.3 1.4 0.47 10.1 1.0 1.6 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension B56 PF01603.15 EIE75492.1 - 1.3e-166 554.2 14.2 1.7e-166 553.9 9.8 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) PfkB PF00294.19 EIE75493.1 - 2.1e-08 33.6 0.3 2.3e-08 33.5 0.2 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Ldh_1_C PF02866.13 EIE75494.1 - 2.7e-47 160.7 0.1 4e-47 160.1 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 EIE75494.1 - 1.6e-45 154.4 0.0 2.6e-45 153.7 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EIE75494.1 - 2.2e-05 23.2 0.0 3.2e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EIE75494.1 - 0.001 19.0 0.2 0.0021 18.0 0.0 1.6 2 0 0 2 2 2 1 NADH(P)-binding Semialdhyde_dh PF01118.19 EIE75494.1 - 0.0017 18.6 0.5 0.0067 16.7 0.0 2.1 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 EIE75494.1 - 0.019 14.3 0.0 0.029 13.7 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DapB_N PF01113.15 EIE75494.1 - 0.065 13.1 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Acyl-CoA_dh_1 PF00441.19 EIE75495.1 - 3.4e-51 173.2 3.6 5.2e-51 172.6 2.5 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EIE75495.1 - 3.4e-26 92.0 0.1 7.5e-26 90.9 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EIE75495.1 - 3.9e-22 77.5 0.2 8.8e-22 76.3 0.2 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EIE75495.1 - 3.6e-17 62.8 0.4 5.8e-17 62.1 0.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 EIE75495.1 - 7.1e-06 25.5 0.2 2e-05 24.1 0.1 1.7 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal SH3_1 PF00018.23 EIE75496.1 - 2.8e-11 42.6 0.4 4.4e-11 41.9 0.3 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EIE75496.1 - 6.6e-10 38.3 0.0 1.5e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EIE75496.1 - 9.2e-10 37.9 0.1 1.5e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_4 PF06347.8 EIE75496.1 - 0.0045 16.4 0.1 0.014 14.9 0.0 1.8 2 0 0 2 2 2 1 Bacterial SH3 domain SH3_3 PF08239.6 EIE75496.1 - 0.037 14.2 0.0 0.092 12.9 0.0 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain GDPD PF03009.12 EIE75497.1 - 2.6e-32 112.3 0.0 4e-32 111.7 0.0 1.3 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family PI-PLC-X PF00388.14 EIE75497.1 - 0.059 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain MULE PF10551.4 EIE75499.1 - 1.6e-09 37.7 0.3 7e-09 35.7 0.0 2.3 2 0 0 2 2 2 1 MULE transposase domain SWIM PF04434.12 EIE75499.1 - 3.5e-05 23.1 0.3 0.0001 21.6 0.2 1.8 1 0 0 1 1 1 1 SWIM zinc finger FA_desaturase PF00487.19 EIE75500.1 - 7.9e-46 156.5 15.4 8.2e-46 156.5 9.5 1.7 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.23 EIE75500.1 - 3.3e-18 65.2 0.1 1.1e-17 63.5 0.1 1.9 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Myc_N PF01056.13 EIE75501.1 - 0.0081 15.3 0.7 0.0085 15.2 0.5 1.0 1 0 0 1 1 1 1 Myc amino-terminal region AF1Q PF15017.1 EIE75501.1 - 0.09 12.6 2.1 0.13 12.2 1.5 1.2 1 0 0 1 1 1 0 Drug resistance and apoptosis regulator CotJB PF12652.2 EIE75503.1 - 0.034 14.2 0.4 0.12 12.4 0.0 2.1 2 0 0 2 2 2 0 CotJB protein Ribosomal_L38e PF01781.13 EIE75505.1 - 8.2e-35 118.3 4.8 8.9e-35 118.2 3.3 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family TFIID_90kDa PF04494.10 EIE75505.1 - 0.026 14.5 0.1 0.028 14.5 0.1 1.1 1 0 0 1 1 1 0 WD40 associated region in TFIID subunit EMA PF02488.10 EIE75505.1 - 0.13 11.7 0.7 0.14 11.5 0.5 1.0 1 0 0 1 1 1 0 Merozoite Antigen PH PF00169.24 EIE75506.1 - 0.00098 19.2 0.1 0.0015 18.6 0.1 1.3 1 1 0 1 1 1 1 PH domain PH_9 PF15410.1 EIE75506.1 - 0.14 12.3 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain p450 PF00067.17 EIE75507.1 - 8e-84 281.7 0.0 1e-83 281.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Thaumatin PF00314.12 EIE75508.1 - 2.6e-47 161.0 17.1 2.7e-46 157.7 11.9 2.0 1 1 0 1 1 1 1 Thaumatin family SPX PF03105.14 EIE75509.1 - 3.2e-38 132.0 11.3 9.7e-38 130.5 7.8 1.7 1 1 0 1 1 1 1 SPX domain Na_sulph_symp PF00939.14 EIE75509.1 - 1.9e-27 96.2 37.2 2.6e-27 95.8 25.8 1.2 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 EIE75509.1 - 1.1e-16 60.3 40.9 1.3e-13 50.2 13.7 2.6 2 1 1 3 3 3 2 Citrate transporter COOH-NH2_lig PF14395.1 EIE75509.1 - 0.067 12.2 2.3 0.8 8.7 0.4 2.2 2 0 0 2 2 2 0 Phage phiEco32-like COOH.NH2 ligase-type 2 RsbRD_N PF14361.1 EIE75509.1 - 0.15 12.5 0.3 0.44 11.0 0.2 1.8 1 0 0 1 1 1 0 RsbT co-antagonist protein rsbRD N-terminal domain DUF465 PF04325.8 EIE75509.1 - 0.82 9.4 5.3 11 5.8 0.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF465) DUF3150 PF11348.3 EIE75509.1 - 4.8 6.2 5.9 13 4.7 0.5 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF3150) Ribosomal_S17e PF00833.13 EIE75512.1 - 3.1 7.5 6.7 3.7 7.3 0.6 3.3 2 2 1 3 3 3 0 Ribosomal S17 YbgS PF13985.1 EIE75512.1 - 3.7 7.4 9.4 0.95 9.3 3.9 2.0 2 0 0 2 2 2 0 YbgS-like protein MUG113 PF13455.1 EIE75514.1 - 7.2e-06 26.3 0.0 9.6e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.4 EIE75514.1 - 0.00012 22.3 0.0 0.00014 22.2 0.0 1.1 1 0 0 1 1 1 1 T5orf172 domain DUF2529 PF10740.4 EIE75516.1 - 0.12 11.8 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2529) KH_1 PF00013.24 EIE75517.1 - 1.1e-12 47.3 0.2 2.2e-06 27.2 0.0 4.3 4 0 0 4 4 4 2 KH domain KH_3 PF13014.1 EIE75517.1 - 3e-11 42.6 1.1 9.2e-06 25.1 0.0 3.1 3 0 0 3 3 3 2 KH domain DUF3638 PF12340.3 EIE75517.1 - 0.0044 16.0 0.1 0.0096 14.9 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) Hat1_N PF10394.4 EIE75518.1 - 2.1e-40 138.4 5.2 2.1e-40 138.4 3.6 1.9 2 0 0 2 2 2 1 Histone acetyl transferase HAT1 N-terminus Fcf2 PF08698.6 EIE75519.1 - 2.4e-36 123.7 2.1 2.4e-36 123.7 1.5 2.7 2 1 0 2 2 2 1 Fcf2 pre-rRNA processing RRN3 PF05327.6 EIE75519.1 - 3.7 5.5 12.8 6.6 4.7 8.8 1.5 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Methyltransf_6 PF03737.10 EIE75521.1 - 1.2e-23 83.7 0.2 1.5e-23 83.3 0.1 1.1 1 0 0 1 1 1 1 Demethylmenaquinone methyltransferase Myb_DNA-bind_6 PF13921.1 EIE75522.1 - 2e-05 24.5 0.0 4.6e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EIE75522.1 - 0.0058 16.6 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Tenui_NS4 PF03300.8 EIE75522.1 - 0.12 11.4 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Tenuivirus non-structural protein NS4 Uricase PF01014.13 EIE75523.1 - 7e-61 204.3 4.5 1.7e-33 115.6 0.1 2.7 2 1 0 2 2 2 2 Uricase Tox-REase-9 PF15650.1 EIE75523.1 - 0.092 12.9 0.0 0.25 11.5 0.0 1.7 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 9 TruD PF01142.13 EIE75524.1 - 6.5e-52 176.4 0.0 5.3e-50 170.1 0.0 2.9 2 1 0 2 2 2 1 tRNA pseudouridine synthase D (TruD) CmcI PF04989.7 EIE75526.1 - 0.12 11.7 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 Cephalosporin hydroxylase zf-C2H2_4 PF13894.1 EIE75527.1 - 0.00079 19.5 1.0 0.0025 18.0 0.7 1.8 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.21 EIE75527.1 - 0.0084 16.4 0.8 0.0084 16.4 0.5 1.9 2 0 0 2 2 2 1 Zinc finger, C2H2 type GPI-anchored PF10342.4 EIE75528.1 - 1.8e-10 41.1 3.7 1.8e-10 41.1 2.6 2.1 1 1 1 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Med20 PF08612.6 EIE75529.1 - 1.4e-28 99.6 0.0 1.6e-28 99.4 0.0 1.1 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex F-box-like PF12937.2 EIE75530.1 - 1.8e-09 37.1 1.4 2.7e-09 36.6 0.3 1.8 2 0 0 2 2 2 1 F-box-like WD40 PF00400.27 EIE75530.1 - 1.2e-05 24.9 1.0 0.033 14.0 0.0 3.7 5 0 0 5 5 5 2 WD domain, G-beta repeat F-box PF00646.28 EIE75530.1 - 1.8e-05 24.2 0.2 3.9e-05 23.1 0.1 1.6 1 0 0 1 1 1 1 F-box domain Sec23_helical PF04815.10 EIE75531.1 - 0.13 11.6 0.6 0.15 11.4 0.4 1.2 1 0 0 1 1 1 0 Sec23/Sec24 helical domain DDE_3 PF13358.1 EIE75533.1 - 9.4e-15 54.6 0.1 1.2e-14 54.3 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE75533.1 - 0.024 14.7 0.0 0.034 14.2 0.0 1.3 1 0 0 1 1 1 0 Integrase core domain HTH_Tnp_Tc3_2 PF01498.13 EIE75534.1 - 4.6e-11 42.6 1.9 5.5e-11 42.3 0.5 1.8 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.1 EIE75534.1 - 0.0057 16.2 0.0 0.014 14.9 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_30 PF13556.1 EIE75534.1 - 0.014 14.9 0.0 0.14 11.7 0.0 2.1 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain DDE_3 PF13358.1 EIE75534.1 - 0.021 14.5 0.0 0.049 13.3 0.0 1.7 1 0 0 1 1 1 0 DDE superfamily endonuclease HTH_29 PF13551.1 EIE75534.1 - 0.051 13.7 0.2 0.11 12.6 0.0 1.6 2 0 0 2 2 2 0 Winged helix-turn helix rve PF00665.21 EIE75535.1 - 1.7e-24 86.1 0.0 2.9e-24 85.4 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 EIE75535.1 - 0.0019 17.7 0.0 0.0052 16.2 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain DDE_3 PF13358.1 EIE75536.1 - 1.5e-20 73.4 0.4 3.9e-20 72.0 0.3 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE75536.1 - 2.5e-10 40.2 1.1 4.5e-10 39.4 0.3 1.8 2 0 0 2 2 2 1 Transposase TrmB PF01978.14 EIE75536.1 - 0.0089 15.7 0.2 0.085 12.5 0.0 2.3 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB RVT_1 PF00078.22 EIE75537.1 - 1.8e-17 63.3 0.0 3.3e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 EIE75537.1 - 0.1 12.9 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 RNase H UBN2 PF14223.1 EIE75538.1 - 0.023 14.4 0.0 0.066 13.0 0.0 1.7 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 EIE75538.1 - 0.032 13.7 0.0 0.071 12.6 0.0 1.6 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type HTH_29 PF13551.1 EIE75539.1 - 2.3e-06 27.7 0.1 4.4e-06 26.8 0.0 1.3 1 1 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.13 EIE75539.1 - 0.0002 21.3 1.1 0.0006 19.8 0.1 1.9 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.1 EIE75539.1 - 0.00081 18.9 0.0 0.0019 17.7 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_7 PF02796.10 EIE75539.1 - 0.002 17.9 0.1 0.0058 16.4 0.1 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_28 PF13518.1 EIE75539.1 - 0.013 15.4 0.0 0.026 14.5 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_38 PF13936.1 EIE75539.1 - 0.021 14.3 0.1 0.046 13.2 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain LacI PF00356.16 EIE75539.1 - 0.022 14.3 2.0 3.4 7.3 0.2 3.0 1 1 2 3 3 3 0 Bacterial regulatory proteins, lacI family HTH_3 PF01381.17 EIE75539.1 - 0.024 14.4 0.3 0.079 12.8 0.1 1.9 2 0 0 2 2 2 0 Helix-turn-helix HTH_IclR PF09339.5 EIE75539.1 - 0.029 13.9 0.0 0.055 13.0 0.0 1.5 1 0 0 1 1 1 0 IclR helix-turn-helix domain Trp_repressor PF01371.14 EIE75539.1 - 0.064 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Trp repressor protein HTH_26 PF13443.1 EIE75539.1 - 0.086 13.0 0.1 0.21 11.8 0.1 1.6 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain F420_ligase PF01996.11 EIE75539.1 - 0.1 11.6 0.1 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 F420-0:Gamma-glutamyl ligase Sigma70_r4_2 PF08281.7 EIE75539.1 - 0.1 12.0 0.1 0.1 12.0 0.0 1.9 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_40 PF14493.1 EIE75539.1 - 0.13 12.4 0.6 0.7 10.1 0.4 2.1 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.13 EIE75540.1 - 5.7e-19 67.9 0.7 5.7e-19 67.9 0.5 2.3 2 1 1 3 3 3 1 Transposase HTH_29 PF13551.1 EIE75540.1 - 5.6e-06 26.4 0.8 1.4e-05 25.1 0.5 1.7 1 1 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.1 EIE75540.1 - 0.00029 21.5 3.6 0.00059 20.5 0.2 2.9 2 1 1 3 3 3 1 Homeodomain-like domain HTH_23 PF13384.1 EIE75540.1 - 0.0012 18.4 0.3 0.056 13.1 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_21 PF13276.1 EIE75540.1 - 0.012 15.6 0.2 0.57 10.2 0.0 3.1 2 1 1 3 3 3 0 HTH-like domain NUMOD3 PF07460.6 EIE75540.1 - 0.093 12.6 0.1 0.5 10.3 0.1 2.2 2 0 0 2 2 2 0 NUMOD3 motif (2 copies) DDE_3 PF13358.1 EIE75543.1 - 3.9e-13 49.3 0.0 5.9e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease FAR1 PF03101.10 EIE75544.1 - 0.00089 19.7 2.3 0.0016 18.9 1.6 1.5 1 0 0 1 1 1 1 FAR1 DNA-binding domain IpaB_EvcA PF03278.8 EIE75545.1 - 0.026 13.7 0.1 0.053 12.7 0.0 1.6 1 1 0 1 1 1 0 IpaB/EvcA family DUF1494 PF07379.6 EIE75545.1 - 0.06 13.2 0.3 0.11 12.3 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1494) rve_3 PF13683.1 EIE75545.1 - 0.098 12.1 0.2 0.28 10.7 0.1 1.9 1 1 0 2 2 2 0 Integrase core domain DDE_3 PF13358.1 EIE75546.1 - 2e-09 37.3 0.1 2.6e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE75547.1 - 3.2e-05 23.9 1.4 4.4e-05 23.4 0.2 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.1 EIE75548.1 - 6.8e-20 71.3 0.1 1.2e-19 70.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE75548.1 - 2.3e-08 33.9 3.0 3.4e-08 33.4 0.2 2.4 1 1 1 2 2 2 1 Transposase HTH_29 PF13551.1 EIE75548.1 - 0.0012 19.0 1.6 0.0035 17.4 1.1 1.9 1 1 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_ISL3 PF13542.1 EIE75548.1 - 0.028 13.5 0.3 0.028 13.5 0.2 2.3 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 rve PF00665.21 EIE75548.1 - 0.048 13.7 0.2 0.13 12.3 0.0 1.9 2 0 0 2 2 2 0 Integrase core domain HTH_23 PF13384.1 EIE75548.1 - 0.46 10.2 2.9 3.7 7.3 0.2 2.5 2 0 0 2 2 2 0 Homeodomain-like domain HTH_32 PF13565.1 EIE75548.1 - 1.3 9.8 5.8 0.28 11.9 0.5 2.4 3 0 0 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.13 EIE75551.1 - 2.7e-18 65.7 3.2 3.4e-18 65.4 1.1 2.1 3 0 0 3 3 3 1 Transposase DDE_3 PF13358.1 EIE75551.1 - 8.5e-16 58.0 0.1 1.5e-15 57.2 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 EIE75551.1 - 4.7e-05 23.4 0.7 0.00017 21.7 0.5 1.9 1 1 0 1 1 1 1 Winged helix-turn helix Ku_PK_bind PF08785.6 EIE75551.1 - 0.002 18.0 0.4 0.0048 16.7 0.0 1.8 2 0 0 2 2 2 1 Ku C terminal domain like HTH_32 PF13565.1 EIE75551.1 - 0.0023 18.6 5.2 0.006 17.3 0.2 3.7 4 1 1 5 5 5 1 Homeodomain-like domain HTH_23 PF13384.1 EIE75551.1 - 0.01 15.4 1.1 0.058 13.0 0.0 2.7 3 0 0 3 3 3 0 Homeodomain-like domain HTH_12 PF08461.5 EIE75551.1 - 0.18 11.5 2.6 0.21 11.3 0.1 2.4 3 0 0 3 3 3 0 Ribonuclease R winged-helix domain DDE_3 PF13358.1 EIE75552.1 - 1.2e-19 70.5 0.1 2.2e-19 69.6 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE75552.1 - 1.1e-09 38.2 1.1 4e-09 36.4 0.8 2.0 1 0 0 1 1 1 1 Transposase HTH_Tnp_4 PF13613.1 EIE75552.1 - 0.00083 18.8 0.0 0.0016 17.9 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease HTH_23 PF13384.1 EIE75552.1 - 0.0044 16.6 0.0 0.013 15.0 0.0 1.8 1 0 0 1 1 1 1 Homeodomain-like domain FAM70 PF14967.1 EIE75552.1 - 0.04 13.1 0.0 0.06 12.5 0.0 1.2 1 0 0 1 1 1 0 FAM70 protein DUF1203 PF06718.6 EIE75555.1 - 0.085 12.6 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1203) Transposase_21 PF02992.9 EIE75556.1 - 6e-22 77.8 0.0 8.9e-22 77.2 0.0 1.2 1 0 0 1 1 1 1 Transposase family tnp2 DUF1258 PF06869.7 EIE75556.1 - 0.0024 17.0 0.0 0.0035 16.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) LysR_substrate PF03466.15 EIE75556.1 - 0.16 11.0 0.0 0.27 10.2 0.0 1.3 1 0 0 1 1 1 0 LysR substrate binding domain Peptidase_M16_C PF05193.16 EIE75558.1 - 3.5e-21 75.7 0.0 4.9e-16 58.9 0.0 3.2 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EIE75558.1 - 5.2e-07 29.5 0.1 0.00024 20.8 0.0 2.6 2 0 0 2 2 2 2 Insulinase (Peptidase family M16) M16C_assoc PF08367.6 EIE75558.1 - 0.00029 19.7 11.3 0.0015 17.4 5.2 3.0 2 1 0 2 2 2 1 Peptidase M16C associated Tctex-1 PF03645.8 EIE75559.1 - 1.1e-22 79.7 0.2 1.3e-22 79.5 0.1 1.0 1 0 0 1 1 1 1 Tctex-1 family DUF1036 PF06282.6 EIE75559.1 - 0.0076 16.5 0.1 0.0087 16.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1036) Ribosomal_L24e PF01246.15 EIE75560.1 - 1.1e-21 76.4 1.2 1.1e-21 76.4 0.8 2.5 2 2 1 3 3 3 1 Ribosomal protein L24e Jun PF03957.8 EIE75561.1 - 0.1 12.3 0.1 0.11 12.2 0.1 1.1 1 0 0 1 1 1 0 Jun-like transcription factor NDT80_PhoG PF05224.7 EIE75562.1 - 3.8e-36 124.8 0.1 3.2e-35 121.8 0.0 2.5 2 1 0 2 2 2 1 NDT80 / PhoG like DNA-binding family ELFV_dehydrog PF00208.16 EIE75563.1 - 3.9e-51 173.9 0.0 7.6e-51 173.0 0.0 1.5 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 EIE75563.1 - 5.5e-28 97.0 0.0 1.2e-20 72.6 0.0 2.6 2 1 0 3 3 3 2 Bacterial NAD-glutamate dehydrogenase NAD_binding_9 PF13454.1 EIE75565.1 - 0.11 12.3 0.2 0.35 10.6 0.2 1.9 1 0 0 1 1 1 0 FAD-NAD(P)-binding DivIVA PF05103.8 EIE75565.1 - 0.28 11.2 4.2 0.41 10.7 0.5 2.5 3 0 0 3 3 3 0 DivIVA protein Ribosomal_S26e PF01283.14 EIE75566.1 - 5.2e-52 174.9 9.0 5.7e-52 174.7 6.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Fer4_10 PF13237.1 EIE75566.1 - 0.25 11.1 3.9 0.77 9.6 1.0 2.0 1 1 1 2 2 2 0 4Fe-4S dicluster domain Zn_ribbon_2 PF12674.2 EIE75566.1 - 0.25 11.6 2.1 1.3 9.3 0.1 2.1 1 1 1 2 2 2 0 Putative zinc ribbon domain Fer4_2 PF12797.2 EIE75566.1 - 0.39 10.7 3.3 0.75 9.8 0.6 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_7 PF12838.2 EIE75566.1 - 0.41 11.0 3.7 3.5 8.0 1.2 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_8 PF13183.1 EIE75566.1 - 0.72 9.9 3.8 1.9 8.5 2.5 1.8 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4 PF00037.22 EIE75566.1 - 1.2 8.8 4.7 0.79 9.4 0.7 2.1 2 0 0 2 2 2 0 4Fe-4S binding domain RRM_6 PF14259.1 EIE75567.1 - 1.7e-05 24.7 0.0 5.2e-05 23.1 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE75567.1 - 0.01 15.6 0.0 0.034 13.9 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HATPase_c PF02518.21 EIE75568.1 - 2.3e-29 101.3 0.1 5.4e-29 100.1 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EIE75568.1 - 1.2e-22 80.0 0.0 2e-21 76.0 0.0 2.9 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 EIE75568.1 - 2.8e-18 65.6 0.2 2.1e-17 62.8 0.0 2.7 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain AAA_16 PF13191.1 EIE75568.1 - 2.8e-12 46.9 0.0 1.3e-11 44.7 0.0 2.2 2 0 0 2 2 1 1 AAA ATPase domain GAF_3 PF13492.1 EIE75568.1 - 1.6e-08 34.7 0.0 4e-08 33.3 0.0 1.8 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.1 EIE75568.1 - 2.9e-08 34.3 0.0 7e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 GAF domain NB-ARC PF00931.17 EIE75568.1 - 1.5e-05 24.0 2.9 0.00019 20.4 2.0 2.3 1 1 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 EIE75568.1 - 0.00022 21.3 1.5 0.0039 17.3 0.0 3.7 4 1 0 4 4 2 1 AAA domain AAA_17 PF13207.1 EIE75568.1 - 0.00066 20.4 2.4 0.035 14.9 0.0 4.4 4 0 0 4 4 4 1 AAA domain Arch_ATPase PF01637.13 EIE75568.1 - 0.00078 19.2 0.1 0.0091 15.7 0.1 2.8 2 1 0 2 2 2 1 Archaeal ATPase GAF PF01590.21 EIE75568.1 - 0.0022 18.1 0.0 0.0044 17.1 0.0 1.5 1 0 0 1 1 1 1 GAF domain AAA_24 PF13479.1 EIE75568.1 - 0.0029 17.2 0.0 0.015 14.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 EIE75568.1 - 0.011 16.0 0.0 0.058 13.6 0.0 2.3 1 0 0 1 1 1 0 ABC transporter Pkinase PF00069.20 EIE75568.1 - 0.012 14.7 0.0 0.028 13.5 0.0 1.6 1 0 0 1 1 1 0 Protein kinase domain TPR_12 PF13424.1 EIE75568.1 - 0.016 15.1 3.4 0.19 11.6 0.2 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat NACHT PF05729.7 EIE75568.1 - 0.023 14.3 0.8 0.21 11.2 0.6 2.6 1 1 0 1 1 1 0 NACHT domain TPR_11 PF13414.1 EIE75568.1 - 0.03 13.9 4.2 0.35 10.5 0.0 3.7 3 0 0 3 3 3 0 TPR repeat AAA PF00004.24 EIE75568.1 - 0.039 14.1 0.0 0.13 12.4 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EIE75568.1 - 0.046 14.0 1.7 0.56 10.5 0.0 3.5 3 0 0 3 3 3 0 AAA domain DUF258 PF03193.11 EIE75568.1 - 0.05 12.7 0.0 0.13 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 CbiA PF01656.18 EIE75568.1 - 0.055 12.8 0.0 0.88 8.9 0.0 2.6 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.13 EIE75568.1 - 0.058 12.5 0.1 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_30 PF13604.1 EIE75568.1 - 0.075 12.6 0.0 0.24 10.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EIE75568.1 - 0.18 11.6 3.9 0.76 9.6 0.5 3.5 2 1 0 2 2 2 0 AAA domain MARVEL PF01284.18 EIE75569.1 - 5.6e-11 42.4 4.4 9.2e-11 41.7 3.0 1.3 1 0 0 1 1 1 1 Membrane-associating domain Mem_trans PF03547.13 EIE75569.1 - 0.0074 14.6 1.7 0.012 13.9 1.2 1.3 1 0 0 1 1 1 1 Membrane transport protein DUF605 PF04652.11 EIE75569.1 - 0.048 13.0 18.8 0.054 12.8 13.1 1.1 1 0 0 1 1 1 0 Vta1 like DUF3635 PF12330.3 EIE75569.1 - 0.057 13.4 0.6 0.12 12.4 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3635) EMP70 PF02990.11 EIE75570.1 - 4.8e-70 236.5 2.2 5.3e-70 236.3 1.5 1.0 1 0 0 1 1 1 1 Endomembrane protein 70 DUF3302 PF11742.3 EIE75570.1 - 0.0013 18.5 0.8 0.026 14.3 0.0 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF3302) zf-DHHC PF01529.15 EIE75570.1 - 0.71 9.2 5.2 47 3.3 0.0 2.2 1 1 0 2 2 2 0 DHHC palmitoyltransferase Ndc1_Nup PF09531.5 EIE75570.1 - 0.87 7.9 10.5 0.23 9.8 3.5 2.3 2 1 0 2 2 2 0 Nucleoporin protein Ndc1-Nup DUF3618 PF12277.3 EIE75571.1 - 0.09 12.8 1.9 6 6.9 0.1 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3618) HTH_22 PF13309.1 EIE75571.1 - 0.13 12.0 0.4 0.13 12.0 0.3 2.8 2 1 1 3 3 3 0 HTH domain Mago_nashi PF02792.9 EIE75571.1 - 0.51 10.0 3.4 0.69 9.6 2.3 1.3 1 1 0 1 1 1 0 Mago nashi protein AAA_13 PF13166.1 EIE75571.1 - 1.1 7.6 22.1 1.3 7.4 15.3 1.1 1 0 0 1 1 1 0 AAA domain DUF1789 PF08748.6 EIE75571.1 - 1.2 9.2 6.2 1.5 8.9 4.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1789) Noelin-1 PF12308.3 EIE75571.1 - 1.6 8.5 10.0 1.3 8.8 0.5 2.4 1 1 1 2 2 2 0 Neurogenesis glycoprotein DUF848 PF05852.6 EIE75571.1 - 1.6 8.5 21.0 1.7 8.4 9.1 2.4 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) HSP70 PF00012.15 EIE75571.1 - 2 6.2 18.3 2.1 6.1 12.7 1.0 1 0 0 1 1 1 0 Hsp70 protein LUC7 PF03194.10 EIE75571.1 - 2.1 7.7 15.5 2.6 7.4 10.8 1.1 1 0 0 1 1 1 0 LUC7 N_terminus CENP-F_leu_zip PF10473.4 EIE75571.1 - 2.1 8.1 32.2 2.7 7.8 22.3 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AKNA PF12443.3 EIE75571.1 - 2.2 8.3 15.3 0.22 11.5 2.0 2.9 1 1 2 3 3 3 0 AT-hook-containing transcription factor AMP-binding_C_2 PF14535.1 EIE75571.1 - 2.2 8.3 6.7 0.99 9.4 2.2 1.9 1 1 1 2 2 2 0 AMP-binding enzyme C-terminal domain CDC37_N PF03234.9 EIE75571.1 - 2.3 8.4 15.6 2.9 8.1 10.8 1.2 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding Prismane PF03063.15 EIE75571.1 - 2.8 6.1 5.5 2.7 6.2 3.8 1.1 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Herpes_UL6 PF01763.11 EIE75571.1 - 3.5 5.7 13.6 0.43 8.6 6.3 1.6 1 1 1 2 2 2 0 Herpesvirus UL6 like DUF948 PF06103.6 EIE75571.1 - 3.8 7.4 17.1 0.43 10.4 1.3 3.0 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) Atg14 PF10186.4 EIE75571.1 - 4.6 6.1 23.8 0.38 9.6 8.4 2.0 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF1664 PF07889.7 EIE75571.1 - 8.1 6.2 17.4 6.3 6.6 0.7 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) HXXSHH PF07586.6 EIE75571.1 - 9 5.1 7.0 11 4.8 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) FimP PF09766.4 EIE75571.1 - 9 5.2 23.1 0.23 10.4 8.3 2.0 1 1 1 2 2 2 0 Fms-interacting protein Fumble PF03630.9 EIE75572.1 - 2.4e-123 411.3 1.1 2.9e-123 411.0 0.8 1.0 1 0 0 1 1 1 1 Fumble Rax2 PF12768.2 EIE75573.1 - 5e-43 147.3 17.0 8.3e-28 97.3 0.3 5.9 3 1 3 6 6 6 6 Cortical protein marker for cell polarity Kelch_6 PF13964.1 EIE75573.1 - 0.024 14.8 6.5 29 5.0 0.0 6.6 5 0 0 5 5 5 0 Kelch motif zf-PARP PF00645.13 EIE75574.1 - 3.3e-14 52.9 0.2 5.2e-14 52.2 0.1 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Nop14 PF04147.7 EIE75574.1 - 6.1 4.6 20.2 7.8 4.2 14.0 1.0 1 0 0 1 1 1 0 Nop14-like family Leader_Erm PF08253.6 EIE75578.1 - 0.33 10.4 0.3 0.33 10.4 0.2 2.1 2 0 0 2 2 2 0 Erm Leader peptide DDE_3 PF13358.1 EIE75580.1 - 2.9e-16 59.5 0.1 5e-16 58.7 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE75580.1 - 4.4e-13 49.0 0.3 1.2e-12 47.7 0.2 1.7 1 0 0 1 1 1 1 Transposase rve PF00665.21 EIE75580.1 - 0.07 13.2 0.0 0.16 12.0 0.0 1.8 1 1 0 1 1 1 0 Integrase core domain HTH_Tnp_4 PF13613.1 EIE75581.1 - 0.0012 18.3 0.0 0.0019 17.7 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease HTH_23 PF13384.1 EIE75581.1 - 0.022 14.4 0.1 0.046 13.3 0.0 1.5 1 1 0 1 1 1 0 Homeodomain-like domain RecX PF02631.11 EIE75581.1 - 0.11 12.6 0.1 0.2 11.8 0.0 1.3 1 1 0 1 1 1 0 RecX family PIP5K PF01504.13 EIE75582.1 - 0.0086 15.2 0.0 0.0086 15.2 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase rve PF00665.21 EIE75582.1 - 0.013 15.6 0.0 0.016 15.3 0.0 1.1 1 0 0 1 1 1 0 Integrase core domain IglC PF11550.3 EIE75582.1 - 0.029 13.6 0.0 0.029 13.6 0.0 1.0 1 0 0 1 1 1 0 Intracellular growth locus C protein DDE_3 PF13358.1 EIE75583.1 - 5.8e-12 45.5 0.5 1.7e-11 44.0 0.2 1.8 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE75583.1 - 2.8e-07 30.5 0.4 1.6e-06 28.0 0.1 2.4 3 0 0 3 3 3 1 Transposase HTH_23 PF13384.1 EIE75583.1 - 3.8e-05 23.1 0.0 0.00014 21.3 0.0 2.0 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.1 EIE75583.1 - 0.007 16.3 0.1 0.051 13.5 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_38 PF13936.1 EIE75583.1 - 0.014 14.9 0.3 0.033 13.7 0.2 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain DDE_Tnp_ISAZ013 PF07592.6 EIE75583.1 - 0.066 11.9 0.0 0.13 10.9 0.0 1.5 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain Sigma70_r4 PF04545.11 EIE75583.1 - 0.081 12.2 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 Trp_repressor PF01371.14 EIE75583.1 - 0.11 12.3 0.1 0.27 11.1 0.1 1.6 1 0 0 1 1 1 0 Trp repressor protein PARP_regulatory PF01358.13 EIE75584.1 - 0.012 14.2 0.5 0.016 13.9 0.3 1.1 1 0 0 1 1 1 0 Poly A polymerase regulatory subunit DEC-1_N PF04625.8 EIE75584.1 - 0.51 8.9 12.9 0.96 8.0 8.9 1.4 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region FlgM PF04316.8 EIE75584.1 - 1.9 8.4 4.8 4.8 7.1 3.3 1.6 1 0 0 1 1 1 0 Anti-sigma-28 factor, FlgM SHR3_chaperone PF08229.6 EIE75585.1 - 0.0071 15.3 0.2 0.013 14.4 0.1 1.4 1 0 0 1 1 1 1 ER membrane protein SH3 3HCDH_N PF02737.13 EIE75585.1 - 0.078 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RVT_1 PF00078.22 EIE75586.1 - 1.4e-16 60.4 0.0 2.9e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EIE75586.1 - 2.4e-07 30.8 0.0 2.6e-06 27.5 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain Asp_protease_2 PF13650.1 EIE75586.1 - 2.7e-06 27.8 0.0 1.2e-05 25.7 0.0 2.3 2 0 0 2 2 2 1 Aspartyl protease Retrotrans_gag PF03732.12 EIE75586.1 - 8e-06 25.8 1.2 1.7e-05 24.8 0.0 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein UBN2_2 PF14227.1 EIE75586.1 - 2.9e-05 23.6 1.4 0.00087 18.8 0.1 3.8 4 1 0 4 4 4 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EIE75586.1 - 0.0003 20.5 0.8 0.21 11.3 0.1 2.9 3 0 0 3 3 3 2 gag-polypeptide of LTR copia-type gag-asp_proteas PF13975.1 EIE75586.1 - 0.00088 19.0 0.0 0.0018 18.0 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.5 EIE75586.1 - 0.0015 17.8 0.0 0.0054 16.1 0.0 2.1 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Transposase_21 PF02992.9 EIE75587.1 - 2e-22 79.4 0.1 3.1e-22 78.7 0.0 1.2 1 0 0 1 1 1 1 Transposase family tnp2 Asp_protease PF09668.5 EIE75588.1 - 0.0018 17.8 0.1 0.0038 16.7 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 EIE75588.1 - 0.0029 18.0 0.2 0.022 15.2 0.0 2.3 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.1 EIE75588.1 - 0.0076 16.0 0.1 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 EIE75588.1 - 0.05 13.5 0.4 0.32 10.9 0.0 2.5 2 0 0 2 2 2 0 Retroviral aspartyl protease Trypan_glycop PF00913.14 EIE75588.1 - 1.3 7.8 5.1 1.9 7.2 3.6 1.3 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein (A-type) DDE_3 PF13358.1 EIE75589.1 - 3.9e-18 65.6 0.1 1.1e-17 64.1 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE75589.1 - 2.3e-08 33.9 0.6 9.5e-08 31.9 0.5 2.0 2 1 0 2 2 2 1 Transposase HTH_Tnp_4 PF13613.1 EIE75590.1 - 0.00013 21.4 0.0 0.00025 20.4 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease HTH_23 PF13384.1 EIE75590.1 - 0.00094 18.7 0.0 0.0018 17.8 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_30 PF13556.1 EIE75590.1 - 0.077 12.6 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain HTH_36 PF13730.1 EIE75590.1 - 0.082 13.0 0.0 0.65 10.1 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain UBN2 PF14223.1 EIE75591.1 - 0.02 14.6 0.0 0.054 13.2 0.0 1.7 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 EIE75591.1 - 0.034 13.6 0.0 0.07 12.6 0.0 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type RVT_1 PF00078.22 EIE75592.1 - 5e-17 61.9 0.0 9.1e-17 61.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 EIE75592.1 - 0.13 12.6 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 RNase H rve PF00665.21 EIE75594.1 - 4.2e-25 88.1 0.0 7.4e-25 87.3 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 EIE75594.1 - 2.2e-11 43.2 0.6 4.8e-11 42.1 0.4 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve_3 PF13683.1 EIE75594.1 - 0.0057 16.1 0.0 0.016 14.7 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 EIE75595.1 - 2.2e-09 36.8 0.6 5.4e-09 35.5 0.1 1.9 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain DUF2870 PF11069.3 EIE75595.1 - 0.04 13.9 1.5 0.059 13.4 0.6 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2870) TcdB_N PF12918.2 EIE75595.1 - 0.083 12.9 0.1 0.083 12.9 0.1 2.0 2 1 0 2 2 2 0 TcdB toxin N-terminal helical domain DUF4110 PF13422.1 EIE75595.1 - 0.58 10.0 4.2 0.45 10.3 1.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4110) SAS4 PF15460.1 EIE75595.1 - 1.1 9.1 5.4 0.74 9.7 1.5 2.2 2 1 0 2 2 2 0 Something about silencing, SAS, complex subunit 4 RVT_1 PF00078.22 EIE75597.1 - 5.9e-30 104.2 0.0 1.1e-29 103.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.18 EIE75597.1 - 1.7e-12 47.7 0.2 3e-12 47.0 0.2 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EIE75597.1 - 1.5e-06 27.8 0.0 2.8e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase zf-CCHC PF00098.18 EIE75597.1 - 0.045 13.6 9.9 0.17 11.8 1.0 2.9 2 0 0 2 2 2 0 Zinc knuckle DnaJ_CXXCXGXG PF00684.14 EIE75597.1 - 0.77 9.8 9.5 9 6.4 2.9 2.5 2 0 0 2 2 2 0 DnaJ central domain zf-RVT PF13966.1 EIE75598.1 - 0.00072 19.8 1.3 0.0025 18.0 0.9 2.0 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase RVT_1 PF00078.22 EIE75599.1 - 3.4e-11 42.9 0.4 2.1e-10 40.3 0.3 2.2 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP PF00077.15 EIE75599.1 - 0.00051 19.9 0.3 0.0021 17.9 0.1 2.2 1 1 1 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 EIE75599.1 - 0.0016 18.8 0.1 0.0037 17.7 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.12 EIE75599.1 - 0.0069 16.4 0.5 0.1 12.7 0.0 2.9 4 0 0 4 4 4 1 Retrotransposon gag protein HTH_Tnp_Tc3_2 PF01498.13 EIE75600.1 - 1.9e-15 56.6 1.3 9.7e-15 54.3 0.1 2.2 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 EIE75600.1 - 8.9e-08 32.2 0.1 2e-07 31.1 0.1 1.6 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EIE75600.1 - 1.2e-07 31.1 0.1 9.3e-05 21.9 0.0 2.6 2 0 0 2 2 2 1 Homeodomain-like domain HTH_7 PF02796.10 EIE75600.1 - 1.2e-06 28.2 3.9 0.00017 21.3 0.3 3.1 2 1 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_32 PF13565.1 EIE75600.1 - 2.5e-06 28.1 0.2 3.5e-05 24.5 0.0 2.6 2 1 1 3 3 3 1 Homeodomain-like domain HTH_36 PF13730.1 EIE75600.1 - 8.1e-05 22.6 1.5 0.006 16.6 0.4 3.1 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_33 PF13592.1 EIE75600.1 - 0.00027 20.3 0.0 0.00088 18.7 0.0 1.8 1 0 0 1 1 1 1 Winged helix-turn helix HTH_24 PF13412.1 EIE75600.1 - 0.00041 19.6 0.4 0.056 12.8 0.1 2.8 3 0 0 3 3 3 1 Winged helix-turn-helix DNA-binding HTH_Tnp_ISL3 PF13542.1 EIE75600.1 - 0.00044 19.3 0.1 0.28 10.3 0.0 2.6 2 0 0 2 2 2 2 Helix-turn-helix domain of transposase family ISL3 HTH_11 PF08279.7 EIE75600.1 - 0.00055 19.5 0.7 0.11 12.1 0.0 2.6 2 1 0 2 2 2 1 HTH domain HTH_21 PF13276.1 EIE75600.1 - 0.00058 19.8 0.0 0.0022 17.9 0.0 1.9 2 0 0 2 2 2 1 HTH-like domain HTH_28 PF13518.1 EIE75600.1 - 0.00075 19.4 0.0 0.1 12.6 0.0 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain TrmB PF01978.14 EIE75600.1 - 0.0021 17.7 0.7 0.022 14.4 0.1 2.4 2 1 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_3 PF01381.17 EIE75600.1 - 0.0037 17.0 0.9 0.081 12.7 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix GerE PF00196.14 EIE75600.1 - 0.0053 16.0 0.2 0.017 14.3 0.1 1.8 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma54_DBD PF04552.8 EIE75600.1 - 0.013 15.0 0.2 0.19 11.2 0.0 2.3 2 0 0 2 2 2 0 Sigma-54, DNA binding domain HTH_40 PF14493.1 EIE75600.1 - 0.014 15.6 0.0 0.052 13.7 0.0 2.0 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_AsnC-type PF13404.1 EIE75600.1 - 0.016 14.7 0.1 0.048 13.2 0.0 1.8 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain LacI PF00356.16 EIE75600.1 - 0.018 14.6 1.4 1.3 8.7 0.1 2.4 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family HTH_22 PF13309.1 EIE75600.1 - 0.026 14.2 0.1 0.078 12.7 0.1 1.8 1 0 0 1 1 1 0 HTH domain HTH_10 PF04967.7 EIE75600.1 - 0.043 13.4 0.1 1.1 8.9 0.0 2.4 2 0 0 2 2 2 0 HTH DNA binding domain DUF977 PF06163.6 EIE75600.1 - 0.048 13.3 1.0 4 7.2 0.0 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF977) HTH_17 PF12728.2 EIE75600.1 - 0.06 13.5 0.0 1.7 8.9 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain GntR PF00392.16 EIE75600.1 - 0.063 12.7 0.0 13 5.3 0.0 2.4 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family HTH_38 PF13936.1 EIE75600.1 - 0.063 12.8 0.7 0.68 9.5 0.0 2.5 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_IclR PF09339.5 EIE75600.1 - 0.079 12.5 0.0 0.42 10.2 0.0 2.1 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_6 PF01418.12 EIE75600.1 - 0.11 12.1 1.0 8.6 6.1 0.1 2.5 2 1 0 2 2 2 0 Helix-turn-helix domain, rpiR family DDE_Tnp_IS1595 PF12762.2 EIE75601.1 - 6.5e-08 32.5 0.1 8.8e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 ISXO2-like transposase domain PH_7 PF15408.1 EIE75601.1 - 0.13 12.1 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain lci PF12197.3 EIE75601.1 - 0.27 10.8 2.2 3.7 7.2 0.0 2.3 2 0 0 2 2 2 0 Bacillus cereus group antimicrobial protein RVT_1 PF00078.22 EIE75602.1 - 3.6e-17 62.4 0.1 7.2e-17 61.4 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 EIE75602.1 - 3e-07 30.8 0.0 7.7e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 EIE75602.1 - 7.8e-07 28.9 0.0 3.6e-06 26.7 0.0 2.2 1 1 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EIE75602.1 - 0.0004 20.1 0.0 0.00089 19.0 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.5 EIE75602.1 - 0.027 14.0 0.1 0.063 12.8 0.1 1.5 1 0 0 1 1 1 0 Aspartyl protease DUF3479 PF11965.3 EIE75602.1 - 0.062 13.0 0.1 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3479) Peptidase_M3_N PF08439.5 EIE75602.1 - 0.1 12.6 0.3 0.1 12.6 0.2 2.0 2 0 0 2 2 2 0 Oligopeptidase F DUF342 PF03961.8 EIE75603.1 - 0.042 12.2 3.2 0.063 11.6 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) IncA PF04156.9 EIE75603.1 - 0.08 12.5 3.6 0.15 11.6 2.5 1.5 1 0 0 1 1 1 0 IncA protein V-SNARE PF05008.10 EIE75603.1 - 0.73 10.0 10.4 0.2 11.8 4.5 2.1 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus V_ATPase_I PF01496.14 EIE75603.1 - 9.7 3.9 8.2 19 2.9 5.3 1.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3391 PF11871.3 EIE75603.1 - 9.9 6.3 8.7 3.6 7.8 0.5 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF3391) rve PF00665.21 EIE75604.1 - 1.3e-24 86.5 0.0 6.2e-24 84.4 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.1 EIE75604.1 - 0.0045 16.4 0.1 0.0096 15.4 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE75605.1 - 3.1e-12 46.2 0.0 5.6e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.1 EIE75606.1 - 2.5e-05 24.0 0.0 5.2e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EIE75606.1 - 3.2e-05 24.3 0.1 0.00013 22.3 0.1 2.0 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.6 EIE75606.1 - 0.1 12.5 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Ank PF00023.25 EIE75608.1 - 4.7e-15 54.5 2.3 4e-06 26.3 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 EIE75608.1 - 2.5e-14 53.3 0.6 1.5e-08 34.9 0.2 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 EIE75608.1 - 1.3e-13 51.0 0.5 1.3e-06 28.6 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EIE75608.1 - 4.2e-09 36.3 0.7 0.0012 19.0 0.1 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIE75608.1 - 5.4e-06 26.1 1.1 0.88 10.0 0.1 4.2 3 0 0 3 3 3 2 Ankyrin repeat Patched PF02460.13 EIE75609.1 - 2.9e-74 250.4 10.6 5.6e-73 246.1 6.2 2.7 2 1 0 2 2 2 1 Patched family Sterol-sensing PF12349.3 EIE75609.1 - 1.4e-51 173.9 5.8 1.4e-51 173.9 4.0 2.7 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.10 EIE75609.1 - 6.4e-06 25.1 1.0 6.4e-06 25.1 0.7 2.3 2 0 0 2 2 2 1 MMPL family ACR_tran PF00873.14 EIE75609.1 - 0.97 6.7 10.3 1.7 5.9 7.1 1.3 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family PRP38 PF03371.10 EIE75610.1 - 1.5e-65 220.0 0.1 1.8e-65 219.8 0.1 1.0 1 0 0 1 1 1 1 PRP38 family Myosin_head PF00063.16 EIE75611.1 - 2.4e-257 855.4 6.5 3.7e-257 854.8 4.5 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.22 EIE75611.1 - 1.9e-16 58.0 37.2 1.5e-05 24.2 0.3 6.6 7 0 0 7 7 7 5 IQ calmodulin-binding motif AAA_22 PF13401.1 EIE75611.1 - 0.0017 18.5 0.8 0.011 15.8 0.1 2.8 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EIE75611.1 - 0.033 14.1 0.1 0.3 11.0 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_19 PF13245.1 EIE75611.1 - 0.093 12.4 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain ADIP PF11559.3 EIE75611.1 - 0.18 11.7 25.8 2.1 8.2 10.8 3.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding ABC_tran PF00005.22 EIE75611.1 - 0.39 11.0 6.9 0.76 10.0 0.0 3.1 3 1 1 4 4 4 0 ABC transporter DUF1029 PF06269.7 EIE75614.1 - 0.13 12.2 0.1 0.17 11.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1029) Lipase_3 PF01764.20 EIE75615.1 - 4.2e-06 26.4 0.0 9.8e-06 25.2 0.0 1.7 2 0 0 2 2 2 1 Lipase (class 3) RabGAP-TBC PF00566.13 EIE75616.1 - 1.2e-54 185.0 1.2 1.2e-54 185.0 0.8 2.6 3 0 0 3 3 3 1 Rab-GTPase-TBC domain bZIP_1 PF00170.16 EIE75616.1 - 0.023 14.6 1.5 0.023 14.6 1.1 4.3 4 1 1 5 5 5 0 bZIP transcription factor XkdW PF09636.5 EIE75616.1 - 0.34 10.8 5.8 0.076 12.8 0.7 2.5 2 0 0 2 2 2 0 XkdW protein DUF4201 PF13870.1 EIE75616.1 - 0.73 9.2 22.3 2.1 7.7 6.7 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Jnk-SapK_ap_N PF09744.4 EIE75616.1 - 0.96 9.4 20.3 0.34 10.8 5.8 2.8 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Mst1_SARAH PF11629.3 EIE75616.1 - 1.5 8.6 6.5 1.4 8.8 0.8 2.9 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 Sugar_tr PF00083.19 EIE75617.1 - 0.0044 15.6 0.4 0.006 15.2 0.3 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter DUF4153 PF13687.1 EIE75617.1 - 0.7 9.3 10.4 1.1 8.6 0.3 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4153) Internalin_N PF12354.3 EIE75617.1 - 4.9 6.8 8.6 13 5.4 0.0 3.3 3 0 0 3 3 3 0 Bacterial adhesion/invasion protein N terminal YqhR PF11085.3 EIE75618.1 - 0.15 11.6 3.8 0.18 11.3 0.1 2.3 1 1 0 2 2 2 0 Conserved membrane protein YqhR DUF1301 PF06979.7 EIE75618.1 - 0.22 11.7 1.3 6.1 6.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1301) FA_hydroxylase PF04116.8 EIE75618.1 - 0.63 10.4 3.3 0.49 10.8 0.3 1.8 1 1 1 2 2 2 0 Fatty acid hydroxylase superfamily DUF1146 PF06612.6 EIE75618.1 - 2.5 8.1 8.3 2.4 8.1 0.4 3.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1146) S4 PF01479.20 EIE75619.1 - 3e-15 55.3 0.0 4.4e-15 54.8 0.0 1.3 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.1 EIE75619.1 - 7.7e-05 22.2 0.0 0.00018 20.9 0.0 1.6 2 0 0 2 2 2 1 S4 domain Ub-Mut7C PF14451.1 EIE75619.1 - 0.034 13.6 0.0 0.062 12.8 0.0 1.3 1 0 0 1 1 1 0 Mut7-C ubiquitin TGS PF02824.16 EIE75619.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 TGS domain Fungal_trans PF04082.13 EIE75620.1 - 2.7e-08 33.0 18.4 1.8e-07 30.3 8.8 3.4 1 1 0 2 2 2 1 Fungal specific transcription factor domain DUF2404 PF10296.4 EIE75621.1 - 1.4e-07 31.5 0.4 4.7e-05 23.4 0.0 2.9 3 0 0 3 3 3 2 Putative integral membrane protein conserved region (DUF2404) Y_phosphatase PF00102.22 EIE75622.1 - 3.6e-26 91.9 0.0 9.9e-26 90.5 0.0 1.7 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.15 EIE75622.1 - 8.3e-15 55.1 0.1 2.2e-14 53.7 0.0 1.8 2 0 0 2 2 2 1 Rhodanese-like domain NIF3 PF01784.13 EIE75624.1 - 1.1e-64 218.3 0.0 1.3e-64 218.0 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) Acyl-CoA_dh_1 PF00441.19 EIE75625.1 - 2.9e-48 163.7 1.6 2.9e-48 163.7 1.1 1.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EIE75625.1 - 1.4e-24 86.8 0.3 4.5e-24 85.1 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EIE75625.1 - 4.8e-22 78.6 0.1 9.7e-22 77.6 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EIE75625.1 - 3.2e-17 61.7 0.0 6.5e-17 60.7 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain PIP5K PF01504.13 EIE75627.1 - 2.5e-63 213.5 0.7 4.4e-63 212.7 0.5 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cytochrom_C1 PF02167.10 EIE75628.1 - 6.5e-87 290.7 0.0 8.1e-87 290.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 EIE75628.1 - 0.00013 22.0 0.0 0.00032 20.7 0.0 1.7 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 EIE75628.1 - 0.014 16.1 1.1 0.058 14.2 0.2 2.5 2 1 0 2 2 2 0 Cytochrome c NUDE_C PF04880.8 EIE75629.1 - 2.9e-11 44.0 8.8 2.9e-11 44.0 6.1 2.2 2 1 1 3 3 2 1 NUDE protein, C-terminal conserved region MSV199 PF10553.4 EIE75629.1 - 0.0058 16.5 8.7 0.039 13.8 2.5 2.3 1 1 1 2 2 2 1 MSV199 domain Filament PF00038.16 EIE75629.1 - 0.011 15.2 3.9 0.011 15.2 2.7 2.4 1 1 0 2 2 2 0 Intermediate filament protein Reo_sigmaC PF04582.7 EIE75629.1 - 0.013 14.7 3.2 0.17 11.0 0.1 2.4 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF730 PF05325.6 EIE75629.1 - 0.016 15.0 1.8 0.016 15.0 1.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF730) DUF904 PF06005.7 EIE75629.1 - 0.021 15.0 31.9 0.065 13.5 6.1 3.9 2 2 2 4 4 4 0 Protein of unknown function (DUF904) BRE1 PF08647.6 EIE75629.1 - 0.04 13.8 16.2 2 8.4 0.2 2.5 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Occludin_ELL PF07303.8 EIE75629.1 - 0.045 14.4 2.0 0.045 14.4 1.4 2.8 1 1 0 2 2 2 0 Occludin homology domain Cortex-I_coil PF09304.5 EIE75629.1 - 0.047 13.7 19.1 0.055 13.5 5.7 2.7 2 1 0 2 2 2 0 Cortexillin I, coiled coil PspA_IM30 PF04012.7 EIE75629.1 - 0.049 12.9 22.3 0.071 12.4 6.5 2.8 3 1 1 4 4 4 0 PspA/IM30 family TPR_MLP1_2 PF07926.7 EIE75629.1 - 0.058 13.1 26.4 0.13 12.0 3.7 2.4 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein TraF_2 PF13729.1 EIE75629.1 - 0.11 11.2 1.1 0.2 10.4 0.0 1.8 2 0 0 2 2 2 0 F plasmid transfer operon, TraF, protein CENP-K PF11802.3 EIE75629.1 - 0.18 11.0 20.6 0.11 11.7 7.4 2.1 1 1 1 2 2 2 0 Centromere-associated protein K CENP-F_leu_zip PF10473.4 EIE75629.1 - 0.18 11.6 27.7 0.61 9.9 3.2 4.0 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CENP-Q PF13094.1 EIE75629.1 - 0.26 11.2 22.3 0.028 14.4 5.2 2.5 2 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit GAS PF13851.1 EIE75629.1 - 0.35 10.0 26.6 0.066 12.4 5.8 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.5 EIE75629.1 - 0.56 10.3 11.6 1.5 8.9 0.6 2.5 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Laminin_II PF06009.7 EIE75629.1 - 0.62 9.8 18.4 5 6.8 0.1 3.6 2 1 2 4 4 4 0 Laminin Domain II DUF3186 PF11382.3 EIE75629.1 - 0.7 8.9 6.3 0.93 8.5 2.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3186) Syntaxin-6_N PF09177.6 EIE75629.1 - 0.86 10.0 17.6 0.46 10.9 1.7 3.6 2 1 2 4 4 3 0 Syntaxin 6, N-terminal Prefoldin_2 PF01920.15 EIE75629.1 - 1.2 8.9 24.5 0.19 11.5 2.1 4.3 2 2 1 3 3 3 0 Prefoldin subunit IncA PF04156.9 EIE75629.1 - 1.3 8.5 26.0 1.8 8.0 7.4 2.2 1 1 0 2 2 2 0 IncA protein DUF2693 PF10902.3 EIE75629.1 - 1.5 8.7 3.8 1.3 9.0 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2693) DUF3810 PF12725.2 EIE75629.1 - 1.7 7.4 7.0 3.7 6.3 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) DUF3450 PF11932.3 EIE75629.1 - 1.7 7.8 17.1 0.57 9.3 5.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) HOOK PF05622.7 EIE75629.1 - 2.1 6.0 22.8 0.02 12.7 2.7 2.1 1 1 0 2 2 2 0 HOOK protein Uds1 PF15456.1 EIE75629.1 - 2.9 7.9 20.9 0.2 11.6 2.0 3.0 3 1 0 3 3 3 0 Up-regulated During Septation DUF2536 PF10750.4 EIE75629.1 - 3.2 7.3 6.1 2 8.0 0.3 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF2536) Med28 PF11594.3 EIE75629.1 - 3.9 7.7 8.8 0.47 10.7 1.9 2.4 2 0 0 2 2 2 0 Mediator complex subunit 28 TMF_TATA_bd PF12325.3 EIE75629.1 - 4.4 7.0 26.9 5.6 6.7 0.0 3.2 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding Atg14 PF10186.4 EIE75629.1 - 6 5.7 18.1 3.9 6.3 6.6 2.1 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 G-gamma PF00631.17 EIE75629.1 - 6.2 6.6 8.6 3.3 7.5 0.4 3.2 3 1 0 3 3 2 0 GGL domain Matrilin_ccoil PF10393.4 EIE75629.1 - 6.7 6.1 7.6 4.8 6.6 0.0 3.4 3 0 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF3571 PF12095.3 EIE75629.1 - 6.7 7.0 12.6 2.1 8.6 0.7 3.3 2 2 1 3 3 3 0 Protein of unknown function (DUF3571) Tho2 PF11262.3 EIE75629.1 - 7.1 5.5 12.8 0.71 8.8 1.8 2.3 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 Iso_dh PF00180.15 EIE75631.1 - 1.2e-76 257.9 0.0 1.4e-76 257.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Ribosomal_S5 PF00333.15 EIE75632.1 - 2.4e-28 97.6 1.6 5.2e-28 96.5 1.1 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 EIE75632.1 - 2.5e-22 77.9 0.0 4.2e-22 77.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain zf-C3HC4_2 PF13923.1 EIE75634.1 - 1.5e-08 34.5 9.6 1.5e-08 34.5 6.7 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIE75634.1 - 6.7e-08 32.0 7.2 6.7e-08 32.0 5.0 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIE75634.1 - 8.2e-08 31.9 11.1 2.4e-07 30.4 7.7 1.9 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EIE75634.1 - 7e-06 25.6 7.3 7e-06 25.6 5.1 2.1 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EIE75634.1 - 0.00036 20.3 9.5 0.00049 19.9 5.2 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 EIE75634.1 - 0.00071 19.2 12.1 0.0014 18.2 8.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EIE75634.1 - 0.015 15.0 13.7 0.03 14.0 1.0 3.1 3 0 0 3 3 3 0 RING-type zinc-finger zf-Apc11 PF12861.2 EIE75634.1 - 0.036 13.9 4.9 0.081 12.7 3.4 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.3 EIE75634.1 - 0.056 12.9 3.0 0.15 11.5 2.1 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-MIZ PF02891.15 EIE75634.1 - 0.68 9.5 9.8 1.6 8.3 6.7 1.7 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger zf-rbx1 PF12678.2 EIE75634.1 - 1 9.5 13.1 0.19 11.8 5.5 2.4 2 1 0 2 2 2 0 RING-H2 zinc finger DUF500 PF04366.7 EIE75635.1 - 7e-28 96.6 0.0 1.2e-27 95.7 0.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF500) SH3_1 PF00018.23 EIE75635.1 - 5.1e-15 54.5 0.1 1e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EIE75635.1 - 8.3e-15 54.1 0.0 1.5e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EIE75635.1 - 8.8e-11 41.1 0.0 1.8e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Acyl-CoA_dh_1 PF00441.19 EIE75636.1 - 2.3e-32 112.1 1.2 3.6e-32 111.5 0.9 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EIE75636.1 - 5.2e-17 61.1 0.1 1.1e-16 60.0 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EIE75636.1 - 1.1e-13 51.7 0.0 2.4e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EIE75636.1 - 3.8e-13 49.8 1.1 6.4e-13 49.1 0.8 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 EIE75636.1 - 0.0018 17.6 0.0 0.0054 16.1 0.0 1.7 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Sec8_exocyst PF04048.9 EIE75636.1 - 0.081 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain Arb1 PF09692.5 EIE75637.1 - 0.0062 15.4 0.0 0.0077 15.1 0.0 1.1 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 IBR PF01485.16 EIE75638.1 - 2.7e-06 27.1 16.3 4.2e-06 26.5 11.3 1.3 1 1 0 1 1 1 1 IBR domain Myb_DNA-bind_4 PF13837.1 EIE75639.1 - 0.0052 16.8 0.2 0.018 15.1 0.2 1.9 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain UBA_3 PF09288.5 EIE75639.1 - 0.085 12.4 2.0 0.64 9.6 0.1 2.4 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain XPG_N PF00752.12 EIE75640.1 - 6.2e-24 84.1 0.6 5.8e-23 81.0 0.0 2.6 3 0 0 3 3 3 1 XPG N-terminal domain XPG_I PF00867.13 EIE75640.1 - 1.8e-22 79.2 0.1 5e-22 77.7 0.1 1.8 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.2 EIE75640.1 - 2.1e-05 24.1 0.3 2.1e-05 24.1 0.2 1.8 2 1 0 2 2 2 1 XPG domain containing 5_3_exonuc PF01367.15 EIE75640.1 - 2.6e-05 24.3 0.8 0.00033 20.8 0.0 2.7 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold TPR_2 PF07719.12 EIE75640.1 - 0.12 12.3 1.4 15 5.7 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Macoilin PF09726.4 EIE75640.1 - 0.46 8.7 9.9 0.67 8.1 6.9 1.1 1 0 0 1 1 1 0 Transmembrane protein Pkinase PF00069.20 EIE75641.1 - 8.1e-70 234.9 0.0 1.2e-69 234.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE75641.1 - 1.3e-47 162.0 0.0 2e-47 161.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 EIE75641.1 - 2.4e-22 79.0 0.6 9e-22 77.2 0.0 2.4 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.1 EIE75641.1 - 4.4e-08 32.4 0.0 6.8e-08 31.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EIE75641.1 - 0.011 15.5 0.8 0.17 11.6 0.1 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family DUF605 PF04652.11 EIE75642.1 - 5.8e-80 269.5 18.5 7.7e-66 223.0 1.4 2.0 1 1 1 2 2 2 2 Vta1 like DEC-1_N PF04625.8 EIE75642.1 - 0.025 13.2 9.5 0.033 12.8 6.6 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region GSK-3_bind PF05350.7 EIE75642.1 - 2.5 7.5 5.7 3.5 6.9 4.0 1.2 1 0 0 1 1 1 0 Glycogen synthase kinase-3 binding Raptor_N PF14538.1 EIE75643.1 - 2e-67 225.8 0.0 8.9e-67 223.7 0.0 2.1 2 0 0 2 2 2 1 Raptor N-terminal CASPase like domain WD40 PF00400.27 EIE75643.1 - 2e-18 65.4 4.7 0.0027 17.5 0.1 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat HEAT_2 PF13646.1 EIE75643.1 - 2.2e-08 34.2 0.6 3.8e-05 23.9 0.0 3.2 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.17 EIE75643.1 - 3.6e-08 32.8 6.9 0.014 15.3 0.0 5.8 6 0 0 6 6 6 2 HEAT repeat Cnd1 PF12717.2 EIE75643.1 - 0.0019 18.0 0.0 1.3 8.8 0.0 3.3 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 EIE75643.1 - 0.011 16.1 0.1 0.64 10.5 0.0 3.7 3 1 1 4 4 4 0 HEAT-like repeat eIF2A PF08662.6 EIE75643.1 - 0.017 14.8 0.1 0.061 13.0 0.0 1.8 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A Thioredoxin_8 PF13905.1 EIE75644.1 - 0.024 14.7 0.1 0.029 14.4 0.0 1.0 1 0 0 1 1 1 0 Thioredoxin-like WWE PF02825.15 EIE75644.1 - 0.087 12.2 0.4 0.19 11.1 0.1 1.6 2 0 0 2 2 2 0 WWE domain SIS PF01380.17 EIE75645.1 - 1.8e-14 53.4 0.0 2.9e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 SIS domain CBS PF00571.23 EIE75645.1 - 1.1e-13 50.7 1.4 7.4e-09 35.2 0.0 3.4 3 0 0 3 3 3 3 CBS domain Exo_endo_phos PF03372.18 EIE75646.1 - 2.1e-22 80.2 0.2 3e-22 79.7 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 EIE75646.1 - 2.2e-13 49.4 5.9 4.9e-07 29.2 0.3 2.7 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EIE75646.1 - 2.1e-08 33.7 9.5 2.8e-05 23.7 2.3 2.4 1 1 2 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 EIE75646.1 - 3.1e-08 32.5 4.6 0.15 12.1 0.0 5.4 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_7 PF13504.1 EIE75646.1 - 0.00022 20.9 1.9 3.9 8.1 0.0 4.6 4 0 0 4 4 4 1 Leucine rich repeat LRR_6 PF13516.1 EIE75646.1 - 0.016 15.2 1.6 36 4.8 0.1 3.9 3 0 0 3 3 3 0 Leucine Rich repeat Pkinase PF00069.20 EIE75647.1 - 8.8e-71 238.0 0.0 1.4e-70 237.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE75647.1 - 4.3e-30 104.6 0.0 7.5e-30 103.8 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE75647.1 - 1.7e-05 23.9 0.0 2.3e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 EIE75647.1 - 0.0029 16.9 0.0 0.0061 15.9 0.0 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.9 EIE75647.1 - 0.013 14.6 0.0 0.026 13.5 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIE75647.1 - 0.013 15.2 0.0 0.021 14.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Glucosamine_iso PF01182.15 EIE75650.1 - 7.1e-67 224.9 0.0 9.1e-67 224.6 0.0 1.1 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase DUF3839 PF12943.2 EIE75650.1 - 0.11 11.6 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3839) RRM_1 PF00076.17 EIE75651.1 - 1.7e-06 27.5 0.2 3.5e-06 26.5 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE75651.1 - 2.4e-05 24.0 0.1 6.1e-05 22.7 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.18 EIE75651.1 - 0.00028 20.6 1.4 0.00054 19.7 1.0 1.5 1 0 0 1 1 1 1 Zinc knuckle RRM_6 PF14259.1 EIE75651.1 - 0.0038 17.1 0.1 0.011 15.6 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-CCHC_6 PF15288.1 EIE75651.1 - 0.023 14.3 0.6 0.04 13.6 0.4 1.4 1 0 0 1 1 1 0 Zinc knuckle TauD PF02668.11 EIE75652.1 - 1.7e-41 142.6 0.4 2.3e-41 142.2 0.3 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.7 EIE75652.1 - 3.7e-10 40.0 0.1 8.9e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.5 EIE75652.1 - 0.0021 17.0 0.0 0.19 10.6 0.0 2.3 2 0 0 2 2 2 2 CsiD DUF4262 PF14081.1 EIE75652.1 - 0.0058 16.7 1.4 0.012 15.7 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4262) 2OG-FeII_Oxy_3 PF13640.1 EIE75652.1 - 0.021 15.2 0.0 0.084 13.3 0.0 2.0 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily RRM_1 PF00076.17 EIE75653.1 - 2.9e-22 78.0 0.1 7.8e-22 76.7 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE75653.1 - 2.7e-16 59.2 0.0 1e-15 57.4 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 EIE75653.1 - 4.9e-09 35.7 0.0 4.9e-09 35.7 0.0 3.3 3 0 0 3 3 2 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.1 EIE75653.1 - 3.8e-08 33.0 0.1 4.2e-07 29.7 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FimP PF09766.4 EIE75653.1 - 0.0018 17.4 9.1 0.003 16.6 6.3 1.3 1 0 0 1 1 1 1 Fms-interacting protein DUF4557 PF15101.1 EIE75653.1 - 0.0049 16.7 6.5 0.011 15.6 4.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4557) zf-C4H2 PF10146.4 EIE75653.1 - 0.013 15.5 8.0 0.71 9.8 0.2 2.4 2 0 0 2 2 2 0 Zinc finger-containing protein CagX PF03524.10 EIE75653.1 - 0.08 12.2 5.6 0.18 11.0 3.9 1.5 1 0 0 1 1 1 0 Conjugal transfer protein Tetraspannin PF00335.15 EIE75653.1 - 0.18 11.0 0.5 0.26 10.5 0.3 1.2 1 0 0 1 1 1 0 Tetraspanin family Suf PF05843.9 EIE75653.1 - 0.29 10.8 10.0 0.028 14.1 3.5 1.8 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF2397 PF09660.5 EIE75653.1 - 0.3 9.6 4.4 3.1 6.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2397) zf-DHHC PF01529.15 EIE75653.1 - 0.34 10.3 2.2 0.59 9.4 1.6 1.3 1 0 0 1 1 1 0 DHHC palmitoyltransferase Serinc PF03348.10 EIE75653.1 - 0.35 9.5 1.3 0.48 9.0 0.9 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF4175 PF13779.1 EIE75653.1 - 0.68 7.5 22.3 0.92 7.1 15.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF4407 PF14362.1 EIE75653.1 - 1.1 8.1 5.4 1.9 7.3 3.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Gag_spuma PF03276.9 EIE75653.1 - 1.6 6.9 20.8 0.021 13.1 8.8 1.9 2 0 0 2 2 2 0 Spumavirus gag protein PAT1 PF09770.4 EIE75653.1 - 2.1 6.4 26.6 0.071 11.3 13.8 1.8 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Paramyxo_ncap PF00973.14 EIE75653.1 - 7.1 5.1 7.9 12 4.4 5.4 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein ER PF01133.12 EIE75654.1 - 0.0069 16.0 0.0 0.013 15.1 0.0 1.5 1 1 0 1 1 1 1 Enhancer of rudimentary Ribosomal_L34e PF01199.13 EIE75655.1 - 7.6e-41 138.2 6.0 9.2e-41 137.9 4.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L34e GFA PF04828.9 EIE75655.1 - 0.093 12.6 0.7 0.33 10.9 0.0 1.9 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Methyltransf_18 PF12847.2 EIE75656.1 - 5.2e-08 33.4 0.0 1.1e-07 32.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIE75656.1 - 8.3e-08 32.2 0.0 1e-05 25.5 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 EIE75656.1 - 3.3e-06 26.4 0.0 5.5e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.10 EIE75656.1 - 1.4e-05 24.5 0.0 0.042 13.2 0.0 2.2 2 0 0 2 2 2 2 Conserved hypothetical protein 95 Methyltransf_23 PF13489.1 EIE75656.1 - 4.3e-05 23.3 0.0 7.6e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 EIE75656.1 - 8.4e-05 21.6 0.0 0.13 11.1 0.0 2.2 1 1 1 2 2 2 2 PRMT5 arginine-N-methyltransferase MTS PF05175.9 EIE75656.1 - 9.6e-05 21.8 0.0 0.0012 18.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_31 PF13847.1 EIE75656.1 - 0.0001 21.9 0.0 0.0002 20.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.7 EIE75656.1 - 0.0028 16.5 0.0 0.025 13.4 0.0 2.0 2 0 0 2 2 2 1 DREV methyltransferase Methyltransf_11 PF08241.7 EIE75656.1 - 0.011 16.1 0.0 0.025 15.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 EIE75656.1 - 0.12 11.3 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_9 PF08003.6 EIE75656.1 - 0.13 10.9 0.0 0.2 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) PI3_PI4_kinase PF00454.22 EIE75657.1 - 6.4e-38 130.5 0.0 2.8e-37 128.4 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 EIE75657.1 - 5.2e-20 71.4 0.0 1.8e-19 69.6 0.0 1.9 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) CBFD_NFYB_HMF PF00808.18 EIE75658.1 - 1.4e-17 63.5 0.4 2.3e-17 62.8 0.3 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Suc_Fer-like PF06999.7 EIE75659.1 - 2.8e-17 63.5 0.0 3.6e-17 63.1 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like DDE_1 PF03184.14 EIE75662.1 - 2.9e-08 33.1 0.6 0.00026 20.1 0.3 2.6 1 1 1 2 2 2 2 DDE superfamily endonuclease CUE PF02845.11 EIE75662.1 - 0.083 12.4 0.1 0.25 10.8 0.0 1.9 1 0 0 1 1 1 0 CUE domain THOC7 PF05615.8 EIE75662.1 - 0.16 12.2 3.1 2.9 8.1 0.1 2.3 2 0 0 2 2 2 0 Tho complex subunit 7 zf-RVT PF13966.1 EIE75663.1 - 1.3e-05 25.4 1.3 1.3e-05 25.4 0.9 1.9 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase RVT_1 PF00078.22 EIE75664.1 - 8.3e-10 38.3 0.1 1.5e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GldM_N PF12081.3 EIE75665.1 - 0.049 13.1 0.0 0.051 13.0 0.0 1.1 1 0 0 1 1 1 0 GldM N-terminal domain DDE_3 PF13358.1 EIE75666.1 - 1.6e-28 99.2 0.0 4.9e-28 97.7 0.0 1.8 1 1 0 1 1 1 1 DDE superfamily endonuclease LRR_6 PF13516.1 EIE75667.1 - 1.5e-15 55.4 21.5 0.28 11.3 0.0 10.3 9 1 1 10 10 10 5 Leucine Rich repeat LRR_4 PF12799.2 EIE75667.1 - 4.3e-10 38.9 19.1 0.62 9.7 0.1 8.5 6 3 2 8 8 8 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EIE75667.1 - 1.7e-06 27.2 11.8 1.2 9.3 0.1 8.1 8 1 1 9 9 9 3 Leucine Rich Repeat LRR_7 PF13504.1 EIE75667.1 - 0.00056 19.6 17.7 5.1 7.7 0.1 8.6 11 0 0 11 11 11 2 Leucine rich repeat LRR_8 PF13855.1 EIE75667.1 - 0.023 14.4 26.2 0.1 12.3 1.6 7.4 5 3 5 10 10 10 0 Leucine rich repeat COG6 PF06419.6 EIE75668.1 - 3.9e-61 206.9 0.2 4.7e-61 206.7 0.1 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 TPR_11 PF13414.1 EIE75671.1 - 0.00023 20.7 0.2 0.032 13.8 0.0 3.0 2 1 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 EIE75671.1 - 0.0058 16.4 2.4 0.083 12.8 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EIE75671.1 - 0.0058 16.1 4.0 0.034 13.7 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EIE75671.1 - 0.017 15.0 0.3 5.1 7.0 0.0 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 EIE75671.1 - 0.29 11.3 9.2 0.1 12.7 1.8 3.2 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EIE75672.1 - 3.5e-07 30.0 3.1 0.0012 18.6 0.1 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 EIE75672.1 - 6.9e-05 22.4 7.8 0.00042 19.8 2.3 3.6 3 1 1 4 4 4 2 TPR repeat TPR_2 PF07719.12 EIE75672.1 - 0.00018 21.1 2.1 0.85 9.6 0.1 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 EIE75672.1 - 0.00034 20.1 4.9 0.3 10.7 0.1 3.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 EIE75672.1 - 0.00081 18.9 7.8 0.15 11.8 0.3 4.2 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 EIE75672.1 - 0.0021 18.3 2.8 0.032 14.5 1.0 3.0 3 1 0 3 3 3 1 Tetratricopeptide repeat ATS3 PF06232.6 EIE75672.1 - 0.027 14.0 0.0 0.061 12.9 0.0 1.6 1 0 0 1 1 1 0 Embryo-specific protein 3, (ATS3) TPR_14 PF13428.1 EIE75672.1 - 0.027 15.0 0.1 91 4.1 0.0 3.6 2 2 1 3 3 3 0 Tetratricopeptide repeat SNAP PF14938.1 EIE75672.1 - 0.033 13.3 5.6 0.066 12.3 2.7 2.2 2 1 0 2 2 2 0 Soluble NSF attachment protein, SNAP TPR_6 PF13174.1 EIE75672.1 - 0.14 12.6 1.6 14 6.4 0.0 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat Peptidase_C50 PF03568.12 EIE75673.1 - 3e-48 164.4 0.9 3.8e-48 164.0 0.6 1.1 1 0 0 1 1 1 1 Peptidase family C50 PTPlike_phytase PF14566.1 EIE75673.1 - 0.075 13.0 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate GRIM-19 PF06212.7 EIE75674.1 - 9.6e-36 122.3 0.0 1.1e-35 122.1 0.0 1.0 1 0 0 1 1 1 1 GRIM-19 protein CRA_rpt PF07046.6 EIE75674.1 - 0.16 12.0 2.4 0.32 10.9 1.7 1.5 1 0 0 1 1 1 0 Cytoplasmic repetitive antigen (CRA) like repeat JHBP PF06585.6 EIE75677.1 - 0.0082 14.9 0.4 0.01 14.6 0.3 1.1 1 0 0 1 1 1 1 Haemolymph juvenile hormone binding protein (JHBP) bZIP_2 PF07716.10 EIE75678.1 - 0.00097 18.9 9.7 0.00097 18.9 6.7 1.6 2 1 0 2 2 1 1 Basic region leucine zipper bZIP_1 PF00170.16 EIE75678.1 - 0.017 15.0 10.2 0.032 14.1 7.0 1.6 1 1 0 1 1 1 0 bZIP transcription factor DUF1948 PF09185.5 EIE75678.1 - 0.02 14.5 1.1 0.027 14.1 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1948) Rabaptin PF03528.10 EIE75678.1 - 0.023 14.6 1.5 0.037 13.9 1.0 1.4 1 0 0 1 1 1 0 Rabaptin DUF3450 PF11932.3 EIE75678.1 - 0.025 13.8 4.0 0.035 13.3 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DivIC PF04977.10 EIE75678.1 - 0.046 13.2 8.4 0.059 12.8 0.9 2.2 1 1 1 2 2 2 0 Septum formation initiator Syntaxin PF00804.20 EIE75678.1 - 0.06 13.5 1.7 0.085 13.0 1.2 1.2 1 0 0 1 1 1 0 Syntaxin Macoilin PF09726.4 EIE75678.1 - 0.13 10.4 7.3 0.16 10.2 5.1 1.1 1 0 0 1 1 1 0 Transmembrane protein CDC37_N PF03234.9 EIE75678.1 - 0.28 11.4 5.6 0.36 11.1 3.9 1.1 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding GAS PF13851.1 EIE75678.1 - 0.29 10.3 9.4 0.41 9.8 6.5 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF4407 PF14362.1 EIE75678.1 - 0.38 9.6 6.5 0.46 9.3 4.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) IncA PF04156.9 EIE75678.1 - 0.41 10.2 4.3 0.54 9.8 2.9 1.2 1 0 0 1 1 1 0 IncA protein UPF0242 PF06785.6 EIE75678.1 - 0.56 8.8 4.5 0.68 8.5 3.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) bZIP_Maf PF03131.12 EIE75678.1 - 0.64 10.3 7.9 1.1 9.5 5.5 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor Vir_act_alpha_C PF10400.4 EIE75678.1 - 1.5 9.2 4.2 1.9 8.8 0.8 2.0 1 1 1 2 2 2 0 Virulence activator alpha C-term DUF904 PF06005.7 EIE75678.1 - 6.7 7.0 9.1 1 9.7 3.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF904) Glyco_hydro_45 PF02015.11 EIE75679.1 - 2.7e-77 259.3 19.4 3.3e-77 259.0 13.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 DDE_3 PF13358.1 EIE75682.1 - 0.00041 20.1 0.0 0.00085 19.0 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 EIE75682.1 - 0.0022 18.0 0.4 0.0037 17.3 0.0 1.6 2 1 0 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.1 EIE75682.1 - 0.007 15.9 0.1 0.018 14.6 0.1 1.7 1 0 0 1 1 1 1 Homeodomain-like domain LZ_Tnp_IS481 PF13011.1 EIE75682.1 - 0.01 16.1 0.3 0.22 11.8 0.0 2.2 2 0 0 2 2 2 1 leucine-zipper of insertion element IS481 DUF3635 PF12330.3 EIE75682.1 - 0.061 13.4 0.3 0.24 11.5 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3635) Glyco_hydro_47 PF01532.15 EIE75683.1 - 8.9e-71 238.8 0.0 1.2e-70 238.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_47 PF01532.15 EIE75684.1 - 3.1e-07 29.4 0.0 3.1e-07 29.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 AMP-binding PF00501.23 EIE75685.1 - 4e-22 78.1 0.0 2.2e-15 56.0 0.0 3.1 2 1 0 2 2 2 2 AMP-binding enzyme Pep3_Vps18 PF05131.9 EIE75688.1 - 3.7e-44 149.7 0.1 1.9e-43 147.4 0.0 2.2 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 EIE75688.1 - 8.6e-15 54.5 12.1 6.6e-11 41.9 4.1 4.0 3 1 2 5 5 5 2 Region in Clathrin and VPS UPRTase PF14681.1 EIE75689.1 - 3.1e-39 134.3 0.0 3.4e-39 134.2 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EIE75689.1 - 0.00014 21.5 0.0 0.00021 20.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GHMP_kinases_N PF00288.21 EIE75690.1 - 7e-18 64.4 0.1 1.5e-17 63.3 0.1 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EIE75690.1 - 1.7e-08 34.5 0.7 3.8e-08 33.4 0.2 1.8 2 0 0 2 2 2 1 GHMP kinases C terminal Ribosomal_S10 PF00338.17 EIE75691.1 - 1.4e-31 108.1 0.7 1.9e-31 107.7 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e MFS_1 PF07690.11 EIE75692.1 - 2e-35 122.1 46.1 1.1e-27 96.6 10.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIE75692.1 - 7.9e-29 100.5 17.7 4.1e-28 98.1 12.3 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter DAGK_cat PF00781.19 EIE75693.1 - 9.3e-23 80.0 0.0 1.7e-22 79.2 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Sugar_tr PF00083.19 EIE75694.1 - 8.5e-52 176.2 23.3 1.1e-51 175.8 16.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIE75694.1 - 5.4e-22 77.9 36.0 2.4e-14 52.8 11.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily GCR1_C PF12550.3 EIE75696.1 - 5.1e-26 90.3 0.7 5.1e-25 87.1 0.2 2.6 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes CD99L2 PF12301.3 EIE75697.1 - 0.0015 18.2 1.4 0.0015 18.2 1.0 2.2 1 1 1 2 2 2 1 CD99 antigen like protein 2 Rifin_STEVOR PF02009.11 EIE75697.1 - 0.015 14.9 1.3 0.018 14.6 0.9 1.1 1 0 0 1 1 1 0 Rifin/stevor family VSP PF03302.8 EIE75697.1 - 0.24 10.0 7.1 0.35 9.4 4.9 1.3 1 1 0 1 1 1 0 Giardia variant-specific surface protein DUF2937 PF11157.3 EIE75697.1 - 0.42 9.9 2.5 0.57 9.5 0.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) TrbL PF04610.9 EIE75697.1 - 1.1 8.9 7.1 1.4 8.5 4.6 1.4 1 1 1 2 2 2 0 TrbL/VirB6 plasmid conjugal transfer protein DUF966 PF06136.8 EIE75697.1 - 1.2 8.4 10.1 1.6 8.0 7.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Herpes_BLLF1 PF05109.8 EIE75697.1 - 5.7 4.7 24.3 5.9 4.7 16.8 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) Macoilin PF09726.4 EIE75697.1 - 5.9 5.0 10.9 6.3 4.9 7.6 1.0 1 0 0 1 1 1 0 Transmembrane protein zf-C2H2_4 PF13894.1 EIE75698.1 - 2.2e-05 24.4 10.4 0.021 15.1 0.2 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EIE75698.1 - 0.00016 21.8 16.0 0.0099 16.1 0.6 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIE75698.1 - 0.011 15.9 11.1 0.18 12.1 0.3 3.1 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EIE75698.1 - 0.046 13.8 0.3 22 5.3 0.1 3.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Ion_trans PF00520.26 EIE75699.1 - 2.4e-109 363.1 80.8 4.6e-39 133.7 11.8 5.5 4 1 1 5 5 5 5 Ion transport protein CBF PF03914.12 EIE75699.1 - 5.6e-42 142.9 0.1 5.6e-42 142.9 0.0 3.8 4 0 0 4 4 4 1 CBF/Mak21 family CDC45 PF02724.9 EIE75699.1 - 0.00039 18.5 13.9 0.00039 18.5 9.6 4.9 5 0 0 5 5 5 2 CDC45-like protein BUD22 PF09073.5 EIE75699.1 - 0.00094 18.3 28.4 0.00094 18.3 19.7 4.3 4 0 0 4 4 4 3 BUD22 Glycos_transf_2 PF00535.21 EIE75700.1 - 1.4e-19 70.4 0.0 1.6e-19 70.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EIE75700.1 - 3.9e-06 26.8 0.0 5.8e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 EIE75700.1 - 0.0053 15.8 0.0 0.0067 15.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Tubulin PF00091.20 EIE75701.1 - 1.1e-47 162.6 0.0 2.1e-47 161.7 0.0 1.5 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EIE75701.1 - 1.6e-47 160.6 0.0 2.7e-47 159.9 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain TPR_19 PF14559.1 EIE75702.1 - 1.6e-13 50.8 0.2 4.3e-06 26.9 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 EIE75702.1 - 3.6e-12 45.7 0.1 5.7e-05 22.6 0.0 3.3 3 0 0 3 3 3 2 TPR repeat TPR_12 PF13424.1 EIE75702.1 - 2.8e-11 43.1 0.8 0.0003 20.6 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 EIE75702.1 - 1.2e-08 34.8 0.2 0.58 10.7 0.0 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 EIE75702.1 - 1.9e-08 33.6 0.0 0.41 10.6 0.0 4.7 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EIE75702.1 - 4e-08 33.2 0.7 0.14 12.8 0.0 5.4 3 1 3 6 6 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 EIE75702.1 - 7.5e-08 32.8 0.0 0.004 17.8 0.0 3.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 EIE75702.1 - 1e-06 28.0 0.1 0.31 10.9 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 EIE75702.1 - 1.6e-06 27.4 3.1 0.59 10.0 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat NARP1 PF12569.3 EIE75702.1 - 1.2e-05 24.3 0.6 0.0088 14.8 0.0 2.1 1 1 1 2 2 2 2 NMDA receptor-regulated protein 1 Apc3 PF12895.2 EIE75702.1 - 7.7e-05 22.7 0.1 0.0024 17.9 0.0 2.7 2 1 1 3 3 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 EIE75702.1 - 0.00021 21.0 0.3 2.8 7.9 0.0 3.7 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EIE75702.1 - 0.00033 20.1 3.3 1.5 8.5 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.1 EIE75702.1 - 0.00077 19.2 0.3 0.037 13.8 0.0 3.0 3 1 1 4 4 3 1 Tetratricopeptide repeat SPOB_a PF14689.1 EIE75702.1 - 0.0014 18.0 0.6 0.062 12.8 0.1 2.7 2 0 0 2 2 2 1 Sensor_kinase_SpoOB-type, alpha-helical domain TPR_17 PF13431.1 EIE75702.1 - 0.002 18.1 1.5 8.4 6.8 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat RPN7 PF10602.4 EIE75702.1 - 0.0037 16.6 0.3 0.017 14.5 0.2 2.3 1 1 0 1 1 1 1 26S proteasome subunit RPN7 Type_III_YscG PF09477.5 EIE75702.1 - 0.007 16.4 0.4 0.021 14.8 0.1 1.9 2 0 0 2 2 2 1 Bacterial type II secretion system chaperone protein (type_III_yscG) TPR_4 PF07721.9 EIE75702.1 - 0.012 15.9 0.0 1.8 9.2 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_15 PF13429.1 EIE75702.1 - 0.013 14.5 0.2 0.013 14.5 0.1 1.6 2 0 0 2 2 2 0 Tetratricopeptide repeat PPR PF01535.15 EIE75702.1 - 0.015 15.2 0.8 0.26 11.3 0.1 3.0 3 0 0 3 3 3 0 PPR repeat Coatomer_E PF04733.9 EIE75702.1 - 0.036 13.2 0.5 0.55 9.3 0.2 2.0 1 1 1 2 2 2 0 Coatomer epsilon subunit PPR_2 PF13041.1 EIE75702.1 - 0.077 12.9 0.9 0.87 9.6 0.3 2.5 2 0 0 2 2 2 0 PPR repeat family Methyltransf_10 PF05971.7 EIE75703.1 - 2e-69 234.0 0.0 1.5e-59 201.6 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF890) MTS PF05175.9 EIE75703.1 - 2.9e-08 33.2 0.0 4.9e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EIE75703.1 - 1.3e-06 28.4 0.0 1.8e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EIE75703.1 - 0.00036 19.7 0.0 0.00058 19.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.13 EIE75703.1 - 0.00045 19.8 0.0 0.0007 19.2 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_18 PF12847.2 EIE75703.1 - 0.00045 20.7 0.0 0.00089 19.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIE75703.1 - 0.00063 20.1 0.0 0.0011 19.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 EIE75703.1 - 0.0019 17.5 0.0 0.0054 16.1 0.0 1.7 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.1 EIE75703.1 - 0.0042 17.4 0.0 0.01 16.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EIE75703.1 - 0.0054 16.3 0.0 0.0069 15.9 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_4 PF02390.12 EIE75703.1 - 0.0075 15.3 0.0 0.015 14.3 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase N6_Mtase PF02384.11 EIE75703.1 - 0.032 13.3 0.2 0.15 11.1 0.0 1.9 2 0 0 2 2 2 0 N-6 DNA Methylase Init_tRNA_PT PF04179.7 EIE75704.1 - 1.3e-98 330.8 0.7 2e-84 284.0 0.1 2.0 1 1 1 2 2 2 2 Initiator tRNA phosphoribosyl transferase DUF2347 PF09804.4 EIE75705.1 - 2.2e-30 105.9 0.1 1.1e-26 93.8 0.1 2.4 1 1 1 2 2 2 2 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.1 EIE75705.1 - 1.3e-07 31.8 0.1 0.0027 17.8 0.0 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF4484) SPA PF08616.5 EIE75705.1 - 0.00051 19.7 0.5 0.0016 18.1 0.1 2.0 2 0 0 2 2 2 1 Stabilization of polarity axis WD40 PF00400.27 EIE75707.1 - 5.6e-51 168.6 12.1 2.4e-11 43.0 0.2 5.6 5 1 1 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 EIE75707.1 - 1.6e-06 26.5 3.3 0.0052 14.9 0.2 3.3 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EIE75707.1 - 1.2e-05 24.2 1.2 0.87 8.2 0.4 3.7 1 1 3 4 4 4 3 Nup133 N terminal like LisH PF08513.6 EIE75707.1 - 0.00031 20.4 0.2 0.00058 19.5 0.1 1.4 1 0 0 1 1 1 1 LisH Sec2p PF06428.6 EIE75707.1 - 0.0089 15.8 1.1 0.017 14.9 0.7 1.4 1 0 0 1 1 1 1 GDP/GTP exchange factor Sec2p N2227 PF07942.7 EIE75708.1 - 1e-91 306.6 0.2 7.9e-91 303.7 0.2 1.9 1 1 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.1 EIE75708.1 - 3.9e-07 29.9 0.0 9.3e-07 28.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIE75708.1 - 8e-05 23.0 0.0 0.00027 21.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIE75708.1 - 0.12 12.8 0.0 0.28 11.6 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain ECH_C PF13766.1 EIE75709.1 - 2.4e-33 114.7 0.4 7.6e-33 113.1 0.1 2.0 2 0 0 2 2 2 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 EIE75709.1 - 1e-30 106.6 0.0 7.2e-30 103.9 0.0 2.0 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Ribosomal_S5_C PF03719.10 EIE75709.1 - 0.096 11.9 0.0 0.78 9.0 0.0 2.1 2 0 0 2 2 2 0 Ribosomal protein S5, C-terminal domain HHH_5 PF14520.1 EIE75710.1 - 0.15 12.2 0.0 12 6.1 0.0 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix domain GPP34 PF05719.6 EIE75711.1 - 5.8e-38 131.0 0.0 7.3e-38 130.6 0.0 1.0 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Diphthamide_syn PF01866.12 EIE75712.1 - 3.4e-69 233.4 2.7 2.5e-35 122.1 0.1 2.6 2 1 0 2 2 2 2 Putative diphthamide synthesis protein Ank PF00023.25 EIE75713.1 - 3.4e-80 260.1 12.1 2.9e-11 42.5 0.0 9.8 10 0 0 10 10 10 9 Ankyrin repeat Ank_2 PF12796.2 EIE75713.1 - 5.2e-78 257.4 20.7 1.2e-17 63.9 0.5 6.2 2 2 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EIE75713.1 - 3.3e-67 215.6 7.7 1.6e-08 33.9 0.0 10.0 10 0 0 10 10 10 9 Ankyrin repeat Ank_4 PF13637.1 EIE75713.1 - 5.3e-62 205.1 9.2 8.3e-14 51.6 0.1 7.7 5 2 2 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 EIE75713.1 - 5.9e-55 182.0 12.0 5.9e-08 32.7 0.0 8.5 4 2 4 8 8 8 8 Ankyrin repeats (many copies) Methyltransf_32 PF13679.1 EIE75716.1 - 3.4e-23 81.9 0.3 5.3e-23 81.2 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIE75716.1 - 0.00027 21.4 0.0 0.00044 20.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIE75716.1 - 0.00058 19.4 0.0 0.00094 18.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain DREV PF05219.7 EIE75716.1 - 0.001 18.0 0.1 0.94 8.2 0.0 2.7 2 1 1 3 3 3 2 DREV methyltransferase MTS PF05175.9 EIE75716.1 - 0.0098 15.2 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 EIE75716.1 - 0.025 14.2 0.0 0.037 13.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 EIE75716.1 - 0.034 14.6 0.0 0.073 13.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EIE75716.1 - 0.039 14.4 0.0 0.076 13.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 EIE75716.1 - 0.068 12.1 0.0 0.079 11.9 0.0 1.4 1 1 0 1 1 1 0 Ribosomal RNA adenine dimethylase FtsJ PF01728.14 EIE75716.1 - 0.069 13.1 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase RD3 PF14473.1 EIE75716.1 - 0.071 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 RD3 protein E1_DerP2_DerF2 PF02221.10 EIE75717.1 - 1.1e-05 25.6 0.0 1.2e-05 25.5 0.0 1.0 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 EIE75717.1 - 0.017 15.1 0.0 0.019 14.9 0.0 1.1 1 0 0 1 1 1 0 ML-like domain zf-C2H2 PF00096.21 EIE75718.1 - 2.5e-08 33.8 30.9 1.6e-05 24.9 0.2 4.7 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIE75718.1 - 9e-07 28.8 26.9 1.2e-06 28.4 1.0 4.7 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EIE75718.1 - 4.7e-05 23.4 26.2 0.00032 20.8 0.1 4.8 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EIE75718.1 - 0.9 9.7 0.1 0.9 9.7 0.1 3.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding FANCAA PF15146.1 EIE75719.1 - 0.0034 16.3 0.1 0.088 11.7 0.0 2.0 2 0 0 2 2 2 2 Fanconi anemia-associated ATP-synt PF00231.14 EIE75720.1 - 8.4e-70 235.3 10.8 9.7e-70 235.1 7.5 1.0 1 0 0 1 1 1 1 ATP synthase Perilipin PF03036.11 EIE75721.1 - 3.7e-15 55.6 17.4 4.5e-11 42.2 0.2 2.5 1 1 1 2 2 2 2 Perilipin family GLTSCR1 PF15249.1 EIE75721.1 - 0.012 15.6 2.6 0.73 9.9 0.1 3.3 2 2 0 2 2 2 0 Glioma tumor suppressor candidate region LOH1CR12 PF10158.4 EIE75721.1 - 0.013 15.3 8.2 0.098 12.4 1.0 3.8 2 1 2 4 4 4 0 Tumour suppressor protein Tox-REase-3 PF15647.1 EIE75721.1 - 3.7 7.3 9.3 4.6 7.0 0.4 3.2 2 1 0 3 3 3 0 Restriction endonuclease fold toxin 3 Chitin_synth_2 PF03142.10 EIE75722.1 - 7.3e-274 909.0 0.1 1.1e-273 908.4 0.1 1.2 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.1 EIE75722.1 - 1.5e-18 67.4 0.0 4.4e-16 59.3 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EIE75722.1 - 3.2e-17 62.8 2.9 1.1e-16 61.1 2.0 1.9 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.1 EIE75722.1 - 5.1e-06 25.8 0.0 0.0012 18.1 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EIE75722.1 - 8e-05 22.3 0.0 0.0024 17.5 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 zf-DHHC PF01529.15 EIE75723.1 - 1.3e-15 57.2 0.7 1.9e-15 56.7 0.5 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase CRC_subunit PF08624.5 EIE75725.1 - 1.4e-40 138.4 0.1 1.8e-40 138.0 0.0 1.1 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Ribosomal_S27 PF01599.14 EIE75726.1 - 5.3e-29 99.7 2.8 1.1e-28 98.8 2.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S27a ubiquitin PF00240.18 EIE75726.1 - 8.4e-18 63.5 0.0 1.9e-17 62.4 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.3 EIE75726.1 - 1.4e-06 27.9 0.0 2.6e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like IBR PF01485.16 EIE75726.1 - 0.012 15.4 0.8 0.019 14.8 0.5 1.4 1 0 0 1 1 1 0 IBR domain ParA PF10609.4 EIE75728.1 - 1.9e-35 120.5 0.3 3.1e-35 119.9 0.2 1.3 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EIE75728.1 - 1.1e-18 67.3 0.0 1.5e-18 66.9 0.0 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 EIE75728.1 - 7.3e-08 31.7 0.0 2.4e-07 30.1 0.0 1.7 1 1 0 1 1 1 1 ATPase MipZ AAA_31 PF13614.1 EIE75728.1 - 1.4e-06 28.3 0.0 6.9e-06 26.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.10 EIE75728.1 - 8.6e-06 25.0 1.3 3.7e-05 22.9 0.6 2.0 2 1 0 2 2 2 1 Anion-transporting ATPase ArgK PF03308.11 EIE75728.1 - 3.2e-05 22.8 0.4 4.1e-05 22.4 0.3 1.1 1 0 0 1 1 1 1 ArgK protein YhjQ PF06564.7 EIE75728.1 - 0.00018 20.9 0.1 0.00067 19.0 0.1 1.8 1 1 0 1 1 1 1 YhjQ protein AAA_25 PF13481.1 EIE75728.1 - 0.0041 16.5 0.2 0.0066 15.8 0.1 1.3 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.15 EIE75728.1 - 0.0059 16.2 0.1 0.0086 15.7 0.1 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase Fer4_NifH PF00142.13 EIE75728.1 - 0.014 14.6 0.1 0.022 13.9 0.1 1.3 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_26 PF13500.1 EIE75728.1 - 0.014 15.0 1.4 0.56 9.7 0.4 2.1 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.17 EIE75728.1 - 0.019 14.4 0.1 0.11 11.8 0.1 1.9 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain MobB PF03205.9 EIE75728.1 - 0.032 13.9 0.0 0.048 13.3 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 EIE75728.1 - 0.066 12.3 0.7 0.14 11.3 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_10 PF12846.2 EIE75728.1 - 0.094 12.1 0.1 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain IstB_IS21 PF01695.12 EIE75728.1 - 0.099 12.0 0.1 0.27 10.6 0.2 1.5 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_19 PF13245.1 EIE75728.1 - 0.38 10.5 2.0 2.7 7.8 0.1 2.5 2 1 0 2 2 2 0 Part of AAA domain Dus PF01207.12 EIE75729.1 - 7.8e-72 241.7 0.0 9.1e-72 241.4 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Oxidored_FMN PF00724.15 EIE75729.1 - 9.8e-05 21.4 0.0 0.00014 21.0 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family His_biosynth PF00977.16 EIE75729.1 - 0.00036 19.8 0.0 0.00072 18.8 0.0 1.5 1 1 0 1 1 1 1 Histidine biosynthesis protein TMP-TENI PF02581.12 EIE75729.1 - 0.0022 17.1 0.0 0.0035 16.4 0.0 1.3 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI DHO_dh PF01180.16 EIE75729.1 - 0.0062 15.5 0.0 0.69 8.8 0.0 2.1 1 1 1 2 2 2 2 Dihydroorotate dehydrogenase NMO PF03060.10 EIE75729.1 - 0.059 12.5 0.0 0.11 11.5 0.0 1.5 1 1 0 1 1 1 0 Nitronate monooxygenase SQS_PSY PF00494.14 EIE75730.1 - 6.7e-41 140.3 0.7 9.1e-41 139.9 0.0 1.5 2 0 0 2 2 2 1 Squalene/phytoene synthase Imm29 PF15575.1 EIE75730.1 - 0.034 13.7 0.2 0.055 13.0 0.1 1.3 1 0 0 1 1 1 0 Immunity protein 29 DUF4468 PF14730.1 EIE75731.1 - 0.078 12.6 0.2 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4468) with TBP-like fold DUF4625 PF15418.1 EIE75731.1 - 0.093 12.8 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4625) WD40 PF00400.27 EIE75732.1 - 8.7e-44 145.8 23.0 1.8e-09 37.1 0.1 10.7 11 0 0 11 11 11 7 WD domain, G-beta repeat Utp12 PF04003.7 EIE75732.1 - 1.2e-18 66.9 0.0 2.1e-18 66.2 0.0 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family PD40 PF07676.7 EIE75732.1 - 0.014 15.0 0.6 0.65 9.7 0.0 3.9 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat RRM_5 PF13893.1 EIE75732.1 - 0.039 13.7 0.0 0.11 12.3 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_M28 PF04389.12 EIE75733.1 - 3.1e-32 111.7 0.0 7.7e-32 110.4 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.23 EIE75733.1 - 5.5e-07 29.2 0.0 8.5e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Nicastrin PF05450.10 EIE75733.1 - 0.00039 19.7 0.6 0.021 14.0 0.0 2.5 3 0 0 3 3 3 1 Nicastrin Rep_3 PF01051.16 EIE75733.1 - 0.0029 17.2 0.4 0.013 15.1 0.1 1.9 2 0 0 2 2 2 1 Initiator Replication protein TA0956 PF11513.3 EIE75733.1 - 0.12 12.3 0.5 0.53 10.3 0.1 2.3 2 0 0 2 2 2 0 Thermoplasma acidophilum protein TA0956 HMG_box PF00505.14 EIE75734.1 - 1.9e-35 120.9 9.0 5.9e-18 64.9 0.4 2.9 3 0 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.5 EIE75734.1 - 2.5e-28 98.2 7.6 2.5e-14 53.4 0.5 2.8 3 0 0 3 3 3 2 HMG-box domain HMG_box_5 PF14887.1 EIE75734.1 - 0.0012 18.6 0.4 0.0035 17.0 0.2 1.8 1 0 0 1 1 1 1 HMG (high mobility group) box 5 DHC PF09626.5 EIE75734.1 - 0.062 13.9 0.3 0.062 13.9 0.2 2.6 3 1 0 3 3 3 0 Dihaem cytochrome c CSTF2_hinge PF14327.1 EIE75734.1 - 8.9 6.4 7.7 2.3 8.3 1.4 2.8 3 0 0 3 3 3 0 Hinge domain of cleavage stimulation factor subunit 2 BRO1 PF03097.13 EIE75735.1 - 2.1e-42 145.2 0.1 2.1e-42 145.2 0.1 1.3 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EIE75735.1 - 3.2e-08 32.9 1.7 3.4e-08 32.7 0.3 1.6 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV Sedlin_N PF04628.8 EIE75735.1 - 0.11 12.3 0.2 0.64 9.8 0.0 2.2 1 1 1 2 2 2 0 Sedlin, N-terminal conserved region polyprenyl_synt PF00348.12 EIE75736.1 - 1.9e-47 161.2 0.2 5e-24 84.5 0.0 2.1 1 1 1 2 2 2 2 Polyprenyl synthetase EGF_CA PF07645.10 EIE75737.1 - 0.14 12.1 6.2 0.27 11.2 4.3 1.5 1 0 0 1 1 1 0 Calcium-binding EGF domain RR_TM4-6 PF06459.7 EIE75737.1 - 0.17 11.7 4.0 0.22 11.3 2.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Dicty_REP PF05086.7 EIE75737.1 - 0.37 8.4 7.2 0.5 8.0 5.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Tir_receptor_C PF07489.6 EIE75737.1 - 0.45 10.2 5.1 0.7 9.6 3.5 1.3 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus zf-C2H2_4 PF13894.1 EIE75737.1 - 0.46 10.9 6.4 1.9 9.0 4.4 2.1 1 0 0 1 1 1 0 C2H2-type zinc finger E1-E2_ATPase PF00122.15 EIE75740.1 - 1.1e-26 93.3 0.0 2.2e-26 92.3 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 EIE75740.1 - 1.3e-16 61.3 0.1 2.3e-16 60.5 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EIE75740.1 - 2.2e-14 54.4 0.0 4.3e-14 53.4 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EIE75740.1 - 0.00025 20.9 0.0 0.00056 19.8 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EIE75740.1 - 0.014 14.9 0.4 0.12 11.9 0.1 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase UPF0233 PF06781.7 EIE75741.1 - 0.066 12.8 0.1 0.081 12.5 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0233) GP41 PF00517.12 EIE75741.1 - 0.1 12.1 0.1 0.12 11.9 0.1 1.1 1 0 0 1 1 1 0 Retroviral envelope protein DUF4451 PF14616.1 EIE75744.1 - 3.6e-26 91.3 7.0 9.5e-26 90.0 4.8 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4451) zf-RING_3 PF14369.1 EIE75744.1 - 0.022 14.7 0.1 0.051 13.5 0.1 1.5 1 0 0 1 1 1 0 zinc-finger zf-A20 PF01754.11 EIE75744.1 - 0.3 10.7 3.8 1.2 8.7 0.1 2.3 2 0 0 2 2 2 0 A20-like zinc finger GPI2 PF06432.6 EIE75745.1 - 1.7e-83 280.2 21.4 9.4e-53 179.3 8.3 2.1 1 1 1 2 2 2 2 Phosphatidylinositol N-acetylglucosaminyltransferase DUF4131 PF13567.1 EIE75745.1 - 0.61 9.4 7.8 0.24 10.7 0.3 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Sel1 PF08238.7 EIE75746.1 - 1.8e-45 152.3 44.9 0.00011 22.7 0.0 19.4 20 1 0 20 20 20 11 Sel1 repeat TPR_11 PF13414.1 EIE75746.1 - 0.00047 19.7 58.5 0.073 12.7 2.2 10.9 7 3 4 12 12 12 7 TPR repeat TPR_1 PF00515.23 EIE75746.1 - 0.0047 16.4 0.2 0.0047 16.4 0.2 12.1 15 0 0 15 15 15 2 Tetratricopeptide repeat TPR_14 PF13428.1 EIE75746.1 - 0.31 11.7 22.0 43 5.1 0.1 9.5 10 0 0 10 10 10 0 Tetratricopeptide repeat TPR_4 PF07721.9 EIE75746.1 - 1.3 9.6 3.9 20 5.9 0.1 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat DNA_pol_B PF00136.16 EIE75748.1 - 1.1e-35 123.3 1.4 1.3e-35 123.1 0.9 1.0 1 0 0 1 1 1 1 DNA polymerase family B G_glu_transpept PF01019.16 EIE75749.1 - 3.2e-26 91.9 0.1 3.8e-26 91.6 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase YpzI PF14140.1 EIE75749.1 - 0.04 13.4 0.0 0.086 12.3 0.0 1.5 1 0 0 1 1 1 0 YpzI-like protein CotH PF08757.6 EIE75750.1 - 8.4e-42 143.5 6.8 1.2e-41 142.9 4.7 1.2 1 0 0 1 1 1 1 CotH protein DivIC PF04977.10 EIE75751.1 - 0.029 13.8 0.5 0.049 13.1 0.3 1.3 1 0 0 1 1 1 0 Septum formation initiator Ribosomal_L11_N PF03946.9 EIE75752.1 - 2.2e-18 65.4 0.1 4.6e-18 64.4 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 EIE75752.1 - 1.7e-12 47.2 0.1 2.9e-12 46.5 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain IF2_N PF04760.10 EIE75752.1 - 0.055 13.1 0.1 0.4 10.3 0.0 2.3 1 1 1 2 2 2 0 Translation initiation factor IF-2, N-terminal region TPX2_importin PF12214.3 EIE75753.1 - 2.1 8.4 29.9 1 9.3 5.3 3.7 1 1 3 4 4 4 0 Cell cycle regulated microtubule associated protein Nop PF01798.13 EIE75754.1 - 1.2e-59 199.9 0.0 2.2e-59 199.0 0.0 1.5 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EIE75754.1 - 4.3e-27 93.6 1.1 9.2e-27 92.6 0.8 1.6 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EIE75754.1 - 1.6e-24 85.7 1.0 1.6e-24 85.7 0.7 2.7 3 0 0 3 3 3 1 NOP5NT (NUC127) domain GAGA_bind PF06217.7 EIE75754.1 - 0.39 10.6 9.7 0.64 9.9 6.7 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family DDHD PF02862.12 EIE75754.1 - 0.42 10.3 6.5 0.72 9.5 4.5 1.4 1 0 0 1 1 1 0 DDHD domain RNase_H2-Ydr279 PF09468.5 EIE75754.1 - 0.5 9.5 19.6 1 8.4 13.6 1.5 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) RNA_polI_A34 PF08208.6 EIE75754.1 - 0.75 9.4 36.0 1.2 8.7 24.9 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Med19 PF10278.4 EIE75754.1 - 1.1 8.9 22.6 2.8 7.5 15.7 1.7 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 RRN3 PF05327.6 EIE75754.1 - 5.9 4.8 12.1 10 4.0 8.4 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.9 EIE75754.1 - 9.8 4.0 14.0 14 3.6 9.7 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2340 PF10209.4 EIE75755.1 - 1.5e-32 112.2 2.4 3.1e-22 78.9 0.4 2.0 1 1 1 2 2 2 2 Uncharacterized conserved protein (DUF2340) UAE_UbL PF14732.1 EIE75755.1 - 0.027 14.5 0.6 0.047 13.7 0.4 1.4 1 0 0 1 1 1 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain B_lectin PF01453.19 EIE75755.1 - 0.064 13.1 0.0 0.082 12.7 0.0 1.2 1 0 0 1 1 1 0 D-mannose binding lectin LysM PF01476.15 EIE75756.1 - 9.1e-11 41.4 0.1 1.7e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 LysM domain WAP PF00095.16 EIE75756.1 - 2.1 8.3 13.1 0.34 10.9 3.2 2.7 2 0 0 2 2 2 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' EamA PF00892.15 EIE75757.1 - 1.6e-11 44.3 22.0 5.2e-11 42.6 10.4 2.3 2 0 0 2 2 2 2 EamA-like transporter family DUF2670 PF10875.3 EIE75757.1 - 0.072 13.1 0.4 0.2 11.6 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2670) EmrE PF13536.1 EIE75757.1 - 1.8 8.8 20.2 0.15 12.2 7.3 3.2 1 1 1 2 2 2 0 Multidrug resistance efflux transporter Fungal_trans PF04082.13 EIE75758.1 - 0.00026 19.9 1.4 0.00026 19.9 1.0 2.7 2 1 0 2 2 2 1 Fungal specific transcription factor domain Metalloenzyme PF01676.13 EIE75759.1 - 6.3e-83 278.0 0.2 7.3e-83 277.8 0.1 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.8 EIE75759.1 - 7.7e-73 244.5 0.0 1.1e-72 244.0 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Phosphodiest PF01663.17 EIE75759.1 - 5.5e-07 29.2 0.0 8.7e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EIE75759.1 - 3.2e-06 26.5 0.0 9.7e-06 24.9 0.0 1.8 2 0 0 2 2 2 1 Sulfatase PglZ PF08665.7 EIE75759.1 - 0.013 15.2 0.0 0.027 14.1 0.0 1.5 1 0 0 1 1 1 0 PglZ domain Alk_phosphatase PF00245.15 EIE75759.1 - 0.052 12.2 0.1 0.49 9.0 0.0 2.1 2 0 0 2 2 2 0 Alkaline phosphatase AIP3 PF03915.8 EIE75760.1 - 1.2e-96 324.2 40.9 1.9e-96 323.5 28.4 1.3 1 0 0 1 1 1 1 Actin interacting protein 3 DUF3446 PF11928.3 EIE75761.1 - 2.2 8.5 8.7 2.5 8.3 2.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) Macoilin PF09726.4 EIE75761.1 - 2.4 6.3 4.2 2.9 6.0 2.9 1.0 1 0 0 1 1 1 0 Transmembrane protein SOG2 PF10428.4 EIE75761.1 - 5.9 5.4 10.1 6.5 5.2 7.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF3671 PF12420.3 EIE75762.1 - 0.32 10.9 2.0 0.37 10.7 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function EF1G PF00647.14 EIE75763.1 - 1.2 8.8 8.0 7.4 6.3 1.2 3.1 3 0 0 3 3 3 0 Elongation factor 1 gamma, conserved domain VHP PF02209.14 EIE75764.1 - 0.052 13.2 0.8 0.081 12.6 0.5 1.4 1 1 0 1 1 1 0 Villin headpiece domain Abhydrolase_2 PF02230.11 EIE75765.1 - 1.8e-19 70.0 0.0 2.4e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EIE75765.1 - 6.6e-08 32.4 0.0 9.9e-08 31.8 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EIE75765.1 - 1.4e-05 24.6 0.0 2e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Esterase PF00756.15 EIE75765.1 - 0.0095 15.3 0.1 0.091 12.1 0.0 2.2 2 1 0 2 2 2 1 Putative esterase Abhydrolase_3 PF07859.8 EIE75765.1 - 0.061 12.8 0.0 0.083 12.4 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 EIE75765.1 - 0.079 12.4 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EIE75765.1 - 0.095 12.5 0.0 0.21 11.4 0.0 1.6 1 1 1 2 2 2 0 Alpha/beta hydrolase family Mito_carr PF00153.22 EIE75766.1 - 1.7e-16 59.6 0.0 2.4e-06 27.1 0.0 4.2 3 1 0 3 3 3 2 Mitochondrial carrier protein TatD_DNase PF01026.16 EIE75768.1 - 4.1e-32 111.3 0.0 5e-32 111.0 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Adaptin_N PF01602.15 EIE75769.1 - 6e-115 384.5 9.1 8.1e-115 384.1 6.3 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EIE75769.1 - 7.4e-25 87.8 4.7 5.1e-23 81.8 0.5 3.1 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EIE75769.1 - 2.3e-15 56.6 5.9 6.1e-07 29.6 0.1 5.3 2 1 4 6 6 6 3 HEAT repeats HEAT PF02985.17 EIE75769.1 - 7.6e-09 34.9 1.9 0.015 15.3 0.0 4.7 6 0 0 6 6 5 2 HEAT repeat HEAT_EZ PF13513.1 EIE75769.1 - 9.3e-08 32.3 2.7 0.48 10.9 0.0 6.2 7 0 0 7 7 7 2 HEAT-like repeat CLASP_N PF12348.3 EIE75769.1 - 0.00083 18.7 3.8 4.1 6.6 0.0 4.4 3 1 0 3 3 3 2 CLASP N terminal Arm PF00514.18 EIE75769.1 - 0.0012 18.6 1.1 1.6 8.6 0.0 4.8 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Arm_2 PF04826.8 EIE75769.1 - 0.056 12.5 3.2 0.037 13.1 0.6 1.9 2 1 0 2 2 2 0 Armadillo-like RasGEF_N_2 PF14663.1 EIE75769.1 - 0.065 13.1 1.6 0.34 10.8 0.0 2.9 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain ParcG PF10274.4 EIE75769.1 - 0.26 11.1 5.8 0.55 10.1 0.0 3.5 4 0 0 4 4 4 0 Parkin co-regulated protein FANCI_S2 PF14676.1 EIE75769.1 - 1.1 9.1 8.1 0.26 11.1 0.2 3.6 3 2 3 6 6 6 0 FANCI solenoid 2 PTPlike_phytase PF14566.1 EIE75770.1 - 1.3e-111 369.2 0.0 3.7e-45 153.6 0.0 3.7 3 0 0 3 3 3 3 Inositol hexakisphosphate DSPc PF00782.15 EIE75770.1 - 1.3e-05 24.8 0.0 0.0028 17.2 0.0 3.8 4 0 0 4 4 4 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EIE75770.1 - 0.0017 18.6 0.0 0.12 12.5 0.0 2.9 2 0 0 2 2 2 1 Tyrosine phosphatase family Pho88 PF10032.4 EIE75771.1 - 3.3e-42 143.8 0.1 4.3e-42 143.5 0.1 1.2 1 0 0 1 1 1 1 Phosphate transport (Pho88) DUF626 PF04776.7 EIE75771.1 - 0.11 12.8 0.1 0.17 12.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF626) DUF2893 PF11459.3 EIE75771.1 - 0.14 11.9 0.2 0.26 11.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknwon function (DUF2893) VTC PF09359.5 EIE75773.1 - 4.7e-74 248.9 0.1 6.5e-73 245.2 0.0 2.1 2 0 0 2 2 2 1 VTC domain DUF202 PF02656.10 EIE75773.1 - 2.4e-10 40.4 1.6 2.4e-10 40.4 1.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SPX PF03105.14 EIE75773.1 - 3.1e-07 30.4 0.7 3.1e-07 30.4 0.5 1.7 2 0 0 2 2 2 1 SPX domain DUF770 PF05591.7 EIE75774.1 - 0.062 12.8 0.0 0.062 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF770) OmdA PF13376.1 EIE75775.1 - 0.011 15.3 1.1 0.032 13.8 0.7 1.8 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated Cytadhesin_P30 PF07271.6 EIE75775.1 - 0.12 11.6 13.7 0.12 11.5 9.5 1.1 1 0 0 1 1 1 0 Cytadhesin P30/P32 Phage_integrase PF00589.17 EIE75777.1 - 9.9e-06 25.3 0.0 1.8e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Phage integrase family Phtf-FEM1B_bdg PF12129.3 EIE75778.1 - 0.015 14.6 0.3 0.028 13.7 0.2 1.4 1 0 0 1 1 1 0 Male germ-cell putative homeodomain transcription factor nsp7 PF08716.5 EIE75778.1 - 0.076 13.4 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 nsp7 replicase Retrotrans_gag PF03732.12 EIE75781.1 - 1.3e-06 28.3 1.7 3.6e-06 26.9 0.1 2.0 2 0 0 2 2 2 1 Retrotransposon gag protein UBN2 PF14223.1 EIE75781.1 - 0.00023 20.9 0.3 0.11 12.2 0.0 2.5 2 0 0 2 2 2 2 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 EIE75781.1 - 0.021 14.3 0.3 0.067 12.7 0.0 1.9 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type rve PF00665.21 EIE75782.1 - 6.3e-23 81.1 0.0 1e-21 77.2 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 EIE75782.1 - 6.5e-17 61.5 0.0 1.2e-16 60.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 EIE75782.1 - 2.4e-06 27.9 0.0 4.4e-05 23.8 0.0 2.8 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.1 EIE75782.1 - 0.0046 16.7 0.0 0.0099 15.6 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.5 EIE75782.1 - 0.0077 15.6 0.1 0.017 14.4 0.0 1.7 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Mhr1 PF12829.2 EIE75783.1 - 0.0032 17.2 0.4 0.0048 16.6 0.3 1.4 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination FdsD PF11390.3 EIE75783.1 - 0.12 12.4 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 NADH-dependant formate dehydrogenase delta subunit FdsD Ion_trans PF00520.26 EIE75785.1 - 0.2 10.8 33.4 0.86 8.8 2.9 4.3 1 1 2 3 3 3 0 Ion transport protein PIF1 PF05970.9 EIE75789.1 - 4.9e-07 29.0 0.2 5.8e-07 28.7 0.1 1.0 1 0 0 1 1 1 1 PIF1-like helicase MalM PF07148.7 EIE75789.1 - 0.1 12.0 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 Maltose operon periplasmic protein precursor (MalM) VTC PF09359.5 EIE75792.1 - 3.2e-22 78.8 2.5 3.2e-22 78.8 1.7 2.7 3 1 0 3 3 3 1 VTC domain DUF202 PF02656.10 EIE75792.1 - 5.2e-08 32.9 3.0 5.2e-08 32.9 2.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SPX PF03105.14 EIE75792.1 - 4.1e-07 30.0 0.6 1.1e-06 28.6 0.2 1.9 2 0 0 2 2 2 1 SPX domain VTC PF09359.5 EIE75793.1 - 6.1e-82 274.8 0.0 9.1e-82 274.2 0.0 1.3 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 EIE75793.1 - 1.2e-09 38.3 6.3 4e-05 23.5 0.4 2.7 2 1 1 3 3 3 2 SPX domain DUF202 PF02656.10 EIE75793.1 - 1.3e-09 38.0 3.3 3.2e-09 36.8 2.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF202) CoA_binding_3 PF13727.1 EIE75793.1 - 0.12 12.2 3.6 0.26 11.0 2.5 1.6 1 0 0 1 1 1 0 CoA-binding domain DUF3037 PF11236.3 EIE75794.1 - 0.27 11.3 3.1 0.4 10.7 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3037) Tropomyosin PF00261.15 EIE75797.1 - 0.0061 15.6 1.8 0.0061 15.6 1.2 1.6 2 0 0 2 2 2 1 Tropomyosin FliJ PF02050.11 EIE75797.1 - 0.013 15.5 4.1 0.013 15.5 2.8 2.1 2 0 0 2 2 2 0 Flagellar FliJ protein AIP3 PF03915.8 EIE75797.1 - 0.068 12.0 14.5 0.086 11.7 10.1 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 DUF1258 PF06869.7 EIE75797.1 - 0.17 10.9 1.8 0.22 10.5 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1258) Peptidase_S49_N PF08496.5 EIE75797.1 - 8.3 6.1 7.4 5.6 6.7 1.3 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DSPc PF00782.15 EIE75798.1 - 1.6e-28 98.9 0.0 2.4e-28 98.3 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.15 EIE75798.1 - 4.6e-12 46.2 0.0 4.3e-09 36.7 0.0 2.3 2 0 0 2 2 2 2 Rhodanese-like domain Y_phosphatase2 PF03162.8 EIE75798.1 - 7.8e-05 22.0 0.0 0.00014 21.3 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Init_tRNA_PT PF04179.7 EIE75798.1 - 0.00031 19.7 0.0 0.00037 19.4 0.0 1.1 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase Myotub-related PF06602.9 EIE75798.1 - 0.00053 18.8 0.0 0.00061 18.6 0.0 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.22 EIE75798.1 - 0.00057 19.2 0.0 0.00096 18.5 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 EIE75798.1 - 0.0098 16.1 0.0 0.018 15.3 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 EIE75798.1 - 0.019 14.9 0.0 0.04 13.9 0.0 1.4 1 1 0 1 1 1 0 Inositol hexakisphosphate SAB PF04382.8 EIE75799.1 - 1.5 8.5 7.7 11 5.7 0.1 3.2 3 0 0 3 3 3 0 SAB domain Cas_Csa5 PF09702.5 EIE75800.1 - 0.0045 17.0 0.1 0.034 14.2 0.0 2.4 2 0 0 2 2 2 1 CRISPR-associated protein (Cas_Csa5) HipA_C PF07804.7 EIE75800.1 - 0.84 9.8 3.5 4 7.6 0.0 3.5 4 0 0 4 4 4 0 HipA-like C-terminal domain PPR_2 PF13041.1 EIE75801.1 - 2.1e-31 107.6 2.7 2e-12 46.8 0.0 9.0 7 2 2 9 9 9 4 PPR repeat family PPR PF01535.15 EIE75801.1 - 2e-23 80.6 0.5 0.0002 21.0 0.0 10.3 10 0 0 10 10 10 4 PPR repeat PPR_3 PF13812.1 EIE75801.1 - 3.7e-23 79.8 5.4 0.013 15.7 0.0 10.2 10 1 0 10 10 9 6 Pentatricopeptide repeat domain TPR_19 PF14559.1 EIE75801.1 - 2.1e-08 34.3 2.9 0.58 10.5 0.1 5.8 6 2 1 7 7 6 2 Tetratricopeptide repeat TPR_2 PF07719.12 EIE75801.1 - 2.1e-07 30.3 1.4 1.6 8.8 0.0 6.0 5 0 0 5 5 5 2 Tetratricopeptide repeat PPR_1 PF12854.2 EIE75801.1 - 6.8e-07 28.6 0.0 2 7.9 0.0 5.8 6 1 0 6 6 6 2 PPR repeat TPR_16 PF13432.1 EIE75801.1 - 6.8e-07 29.7 0.8 30 5.4 0.0 7.4 7 2 1 9 9 7 0 Tetratricopeptide repeat ECSIT PF06239.6 EIE75801.1 - 3.1e-06 26.2 0.1 1.5 7.6 0.0 4.3 3 1 1 4 4 4 3 Evolutionarily conserved signalling intermediate in Toll pathway TPR_1 PF00515.23 EIE75801.1 - 2.3e-05 23.7 3.7 0.49 10.1 0.1 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat Apc3 PF12895.2 EIE75801.1 - 9e-05 22.5 3.3 1.5 9.0 0.0 4.7 5 1 1 6 6 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 EIE75801.1 - 0.00011 21.7 7.2 11 5.7 0.1 5.9 5 1 1 6 6 6 0 TPR repeat TPR_8 PF13181.1 EIE75801.1 - 0.00016 21.2 2.8 0.61 9.9 0.1 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 EIE75801.1 - 0.00057 19.4 0.2 1.1 9.2 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 EIE75801.1 - 0.023 15.1 2.2 51 4.6 0.0 5.5 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_17 PF13431.1 EIE75801.1 - 0.047 13.8 0.7 0.66 10.3 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 EIE75801.1 - 0.047 13.6 5.4 0.53 10.2 0.1 5.0 6 1 0 6 6 6 0 Tetratricopeptide repeat BTAD PF03704.12 EIE75801.1 - 0.058 13.6 0.5 41 4.4 0.1 3.6 3 0 0 3 3 3 0 Bacterial transcriptional activator domain DSPc PF00782.15 EIE75802.1 - 1.9e-08 33.9 0.0 3.1e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EIE75802.1 - 7e-08 32.1 0.0 3.1e-06 26.6 0.0 2.3 1 1 1 2 2 2 1 Protein-tyrosine phosphatase CDKN3 PF05706.7 EIE75802.1 - 0.0058 16.1 0.0 0.0082 15.6 0.0 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.1 EIE75802.1 - 0.019 14.9 0.0 0.039 13.9 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate Opi1 PF08618.5 EIE75803.1 - 3.6e-31 108.5 2.1 5.8e-30 104.5 1.5 2.0 1 1 0 1 1 1 1 Transcription factor Opi1 Pro_isomerase PF00160.16 EIE75804.1 - 7.6e-47 159.3 0.2 1.2e-46 158.7 0.1 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 EIE75804.1 - 2.5e-17 62.2 4.3 1.4e-10 40.6 0.1 2.4 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 EIE75804.1 - 1.7e-16 58.6 0.3 4.5e-06 26.1 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 EIE75804.1 - 5.7e-14 51.0 0.7 3.9e-06 26.2 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 EIE75804.1 - 9.5e-09 34.4 0.9 0.069 12.9 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EIE75804.1 - 7.9e-07 28.9 0.1 0.02 14.8 0.0 2.8 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 EIE75804.1 - 4.8e-06 25.9 0.0 0.066 13.0 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EIE75804.1 - 6.3e-06 26.3 0.0 0.0013 19.1 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 EIE75804.1 - 0.00031 20.9 0.6 2.1 9.0 0.0 4.0 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EIE75804.1 - 0.00046 20.7 0.2 0.31 11.7 0.2 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EIE75804.1 - 0.00063 20.0 0.4 0.19 12.0 0.1 3.0 2 1 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 EIE75804.1 - 0.021 14.9 4.0 0.29 11.3 0.3 2.7 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EIE75804.1 - 0.077 12.8 0.0 0.28 11.0 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat HEAT PF02985.17 EIE75805.1 - 6.9e-27 91.0 8.0 2.3e-05 24.1 0.1 10.8 10 0 0 10 10 10 4 HEAT repeat HEAT_EZ PF13513.1 EIE75805.1 - 2.2e-23 82.0 3.2 1.5e-06 28.4 0.1 11.1 8 2 4 12 12 12 5 HEAT-like repeat HEAT_2 PF13646.1 EIE75805.1 - 1.5e-22 79.6 7.0 2.5e-07 30.8 0.1 8.1 5 2 3 8 8 8 4 HEAT repeats Vac14_Fab1_bd PF12755.2 EIE75805.1 - 2.4e-13 50.2 0.1 0.00046 20.5 0.0 7.1 6 1 2 8 8 8 4 Vacuolar 14 Fab1-binding region IBN_N PF03810.14 EIE75805.1 - 1.1e-10 41.2 0.4 8e-10 38.4 0.1 2.8 2 0 0 2 2 1 1 Importin-beta N-terminal domain CLASP_N PF12348.3 EIE75805.1 - 2.4e-08 33.6 0.1 0.02 14.2 0.0 5.0 4 2 0 4 4 4 2 CLASP N terminal Ipi1_N PF12333.3 EIE75805.1 - 3.7e-08 33.2 0.0 0.063 13.2 0.0 5.1 3 1 1 4 4 4 2 Rix1 complex component involved in 60S ribosome maturation Adaptin_N PF01602.15 EIE75805.1 - 4.9e-06 25.1 4.1 0.02 13.2 0.1 4.2 3 2 1 4 4 4 3 Adaptin N terminal region Cnd1 PF12717.2 EIE75805.1 - 6.8e-06 26.0 0.4 0.2 11.4 0.0 4.1 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 DUF2454 PF10521.4 EIE75805.1 - 0.00026 20.0 0.6 0.0043 16.1 0.0 3.3 4 0 0 4 4 4 1 Protein of unknown function (DUF2454) MMS19_C PF12460.3 EIE75805.1 - 0.00052 18.8 0.9 0.17 10.5 0.0 4.5 4 1 1 5 5 5 1 RNAPII transcription regulator C-terminal CTD_bind PF04818.8 EIE75805.1 - 0.012 15.8 0.0 23 5.3 0.0 4.1 3 0 0 3 3 3 0 RNA polymerase II-binding domain. TIP120 PF08623.5 EIE75805.1 - 0.19 11.2 2.6 5.5 6.5 0.0 3.8 4 0 0 4 4 4 0 TATA-binding protein interacting (TIP20) Arm PF00514.18 EIE75805.1 - 0.99 9.3 9.2 11 6.0 0.0 6.2 7 1 1 8 8 8 0 Armadillo/beta-catenin-like repeat Proteasome PF00227.21 EIE75806.1 - 6.9e-60 201.5 0.4 1e-59 201.0 0.3 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EIE75806.1 - 1.6e-11 43.3 0.3 3.5e-11 42.1 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature RasGEF PF00617.14 EIE75807.1 - 2.5e-48 164.2 2.2 5.2e-48 163.2 1.5 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EIE75807.1 - 6.6e-07 29.3 0.3 6.6e-07 29.3 0.2 3.0 2 1 1 3 3 3 1 RasGEF N-terminal motif TACC PF05010.9 EIE75808.1 - 0.31 10.7 7.1 0.41 10.3 4.9 1.1 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) HATPase_c PF02518.21 EIE75809.1 - 2.7e-26 91.4 0.8 7.3e-26 90.0 0.3 2.0 2 0 0 2 2 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EIE75809.1 - 2.7e-19 68.9 0.0 1.3e-18 66.7 0.0 2.3 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.19 EIE75809.1 - 4.1e-18 65.4 0.0 3.6e-17 62.3 0.0 2.3 2 0 0 2 2 2 1 Response regulator receiver domain AAA_16 PF13191.1 EIE75809.1 - 7.5e-15 55.3 0.0 2.3e-14 53.7 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain Pkinase PF00069.20 EIE75809.1 - 8.1e-13 48.1 0.0 2e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain GAF_3 PF13492.1 EIE75809.1 - 2.5e-11 43.7 0.0 7.2e-11 42.2 0.0 1.9 1 0 0 1 1 1 1 GAF domain GAF PF01590.21 EIE75809.1 - 1.7e-08 34.6 0.0 3.3e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.1 EIE75809.1 - 1.4e-06 28.9 0.0 4.1e-06 27.3 0.0 1.9 1 0 0 1 1 1 1 GAF domain NB-ARC PF00931.17 EIE75809.1 - 4.5e-06 25.7 0.0 1.1e-05 24.4 0.0 1.6 1 1 0 1 1 1 1 NB-ARC domain NACHT PF05729.7 EIE75809.1 - 3.2e-05 23.6 0.1 9.4e-05 22.1 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EIE75809.1 - 0.00087 19.4 0.2 0.0088 16.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain HATPase_c_3 PF13589.1 EIE75809.1 - 0.002 17.7 0.2 0.0085 15.7 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ABC_tran PF00005.22 EIE75809.1 - 0.011 16.0 0.0 0.034 14.4 0.0 1.8 1 0 0 1 1 1 0 ABC transporter Pkinase_Tyr PF07714.12 EIE75809.1 - 0.014 14.4 0.0 2.9 6.8 0.0 2.4 2 0 0 2 2 2 0 Protein tyrosine kinase IstB_IS21 PF01695.12 EIE75809.1 - 0.049 13.0 0.7 0.15 11.4 0.0 2.1 3 0 0 3 3 2 0 IstB-like ATP binding protein DUF258 PF03193.11 EIE75809.1 - 0.067 12.3 0.0 0.15 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AA_permease_2 PF13520.1 EIE75810.1 - 5.1e-66 222.9 49.7 5.1e-66 222.9 34.5 1.6 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.16 EIE75810.1 - 4e-31 107.8 42.9 5.5e-31 107.4 29.7 1.0 1 0 0 1 1 1 1 Amino acid permease MFS_1 PF07690.11 EIE75811.1 - 1.6e-24 86.3 16.8 1.9e-24 86.0 11.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily RseC_MucC PF04246.7 EIE75811.1 - 0.071 12.6 4.2 0.6 9.6 0.2 2.5 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DUF485 PF04341.7 EIE75811.1 - 7.1 6.4 7.2 8.5 6.1 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function, DUF485 eRF1_2 PF03464.10 EIE75812.1 - 3.6e-44 150.2 0.0 5.8e-44 149.6 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 EIE75812.1 - 8.6e-38 129.0 0.0 1.9e-37 127.9 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 EIE75812.1 - 2.9e-28 98.0 0.1 5.8e-28 97.1 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 Ribosomal_L7Ae PF01248.21 EIE75812.1 - 0.12 11.9 0.0 0.38 10.3 0.0 1.8 2 0 0 2 2 2 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family CAP_GLY PF01302.20 EIE75813.1 - 9.4e-19 66.8 0.0 1.7e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 CAP-Gly domain BTB PF00651.26 EIE75813.1 - 1.4e-15 57.2 1.9 2e-11 43.8 0.4 2.6 2 0 0 2 2 2 2 BTB/POZ domain 14-3-3 PF00244.15 EIE75814.1 - 5.2e-40 136.9 6.3 5.7e-40 136.8 4.4 1.0 1 0 0 1 1 1 1 14-3-3 protein Med29 PF11568.3 EIE75814.1 - 0.0029 17.6 0.8 0.01 15.8 0.1 1.9 1 1 0 2 2 2 1 Mediator complex subunit 29 Orbi_VP5 PF00901.12 EIE75814.1 - 0.011 14.0 2.5 0.012 13.8 1.7 1.0 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 DUF837 PF05769.6 EIE75814.1 - 0.014 14.9 2.5 0.077 12.5 0.1 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF837) MP PF01107.13 EIE75814.1 - 0.05 12.9 0.4 0.061 12.6 0.2 1.1 1 0 0 1 1 1 0 Viral movement protein (MP) 4HBT_3 PF13622.1 EIE75815.1 - 1.3e-35 123.3 0.1 1.7e-35 123.0 0.1 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 EIE75815.1 - 2.3e-21 75.7 0.0 1e-14 54.2 0.0 3.0 2 1 0 2 2 2 2 Acyl-CoA thioesterase Chitin_synth_1 PF01644.12 EIE75818.1 - 3.7e-84 280.4 0.1 5.5e-84 279.9 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.10 EIE75818.1 - 2.9e-20 72.1 8.6 2.6e-18 65.7 0.0 2.5 3 0 0 3 3 3 2 Chitin synthase Chitin_synth_1N PF08407.6 EIE75818.1 - 8.3e-11 41.4 0.2 1.9e-10 40.2 0.1 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.1 EIE75818.1 - 2.6e-09 37.0 0.4 2.6e-09 37.0 0.3 2.6 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EIE75818.1 - 2.4e-06 27.5 0.0 4.5e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 ABC_tran PF00005.22 EIE75819.1 - 9.6e-37 126.3 0.0 2.5e-36 125.0 0.0 1.8 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EIE75819.1 - 1.1e-30 106.9 15.5 1.1e-30 106.9 10.7 2.3 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.14 EIE75819.1 - 1.8e-07 30.5 1.4 7e-06 25.4 1.0 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EIE75819.1 - 2.1e-06 27.9 2.8 4.5e-05 23.5 0.0 3.1 3 1 0 3 3 3 1 AAA domain AAA_16 PF13191.1 EIE75819.1 - 0.00088 19.3 0.0 0.0027 17.7 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 EIE75819.1 - 0.0017 17.5 0.0 0.0036 16.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SbcCD_C PF13558.1 EIE75819.1 - 0.0059 16.4 0.2 0.063 13.2 0.2 2.4 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 EIE75819.1 - 0.0074 15.7 1.2 0.013 15.0 0.1 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA PF00004.24 EIE75819.1 - 0.0077 16.4 0.1 0.1 12.7 0.0 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EIE75819.1 - 0.0081 16.0 0.4 0.23 11.3 0.0 3.1 3 1 0 3 3 3 1 AAA domain AAA_22 PF13401.1 EIE75819.1 - 0.017 15.2 0.2 0.14 12.2 0.1 2.3 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EIE75819.1 - 0.021 15.6 0.0 0.059 14.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EIE75819.1 - 0.04 13.6 0.2 0.67 9.6 0.1 2.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Thioredoxin_4 PF13462.1 EIE75820.1 - 1.3e-15 57.7 0.0 1.9e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin IF2_N PF04760.10 EIE75820.1 - 0.0037 16.9 0.6 0.019 14.6 0.1 2.3 2 1 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region DSBA PF01323.15 EIE75820.1 - 0.007 15.9 0.6 0.32 10.5 0.2 2.3 2 0 0 2 2 2 2 DSBA-like thioredoxin domain RE_NgoPII PF09521.5 EIE75820.1 - 0.076 11.7 0.0 0.24 10.1 0.0 1.5 1 1 0 2 2 2 0 NgoPII restriction endonuclease Proteasome PF00227.21 EIE75821.1 - 1e-34 119.4 0.1 1.4e-18 66.8 0.0 2.0 1 1 1 2 2 2 2 Proteasome subunit Bromodomain PF00439.20 EIE75822.1 - 2.2e-23 81.9 0.5 2.7e-23 81.6 0.3 1.1 1 0 0 1 1 1 1 Bromodomain SNF2_N PF00176.18 EIE75823.1 - 1.6e-69 233.9 1.8 2.1e-69 233.5 1.2 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EIE75823.1 - 4.8e-18 64.8 0.0 1.6e-17 63.1 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIE75823.1 - 4.5e-07 29.8 0.0 1.1e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EIE75823.1 - 4.2e-05 23.0 0.0 9.5e-05 21.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C_4 PF13871.1 EIE75823.1 - 0.05 13.0 0.0 0.091 12.1 0.0 1.4 1 0 0 1 1 1 0 Helicase_C-like Metallophos PF00149.23 EIE75824.1 - 5.9e-44 149.8 0.6 7.4e-44 149.5 0.4 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase cwf21 PF08312.7 EIE75824.1 - 0.035 13.9 0.5 0.06 13.2 0.3 1.3 1 0 0 1 1 1 0 cwf21 domain HLH PF00010.21 EIE75825.1 - 5.3e-06 26.0 3.6 1.1e-05 24.9 2.5 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Med4 PF10018.4 EIE75825.1 - 0.049 13.0 2.9 0.091 12.1 2.0 1.5 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 OrfB_Zn_ribbon PF07282.6 EIE75826.1 - 0.075 12.6 0.0 0.21 11.2 0.0 1.9 1 1 0 1 1 1 0 Putative transposase DNA-binding domain DUF362 PF04015.7 EIE75826.1 - 0.11 11.9 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF362) EF-hand_like PF09279.6 EIE75826.1 - 0.12 12.4 0.2 0.25 11.3 0.1 1.6 1 0 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like Glyco_hydro_17 PF00332.13 EIE75827.1 - 0.014 14.4 2.5 0.41 9.6 0.1 2.2 1 1 0 2 2 2 0 Glycosyl hydrolases family 17 Complex1_51K PF01512.12 EIE75829.1 - 4.7e-49 166.0 0.0 6.8e-49 165.4 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 EIE75829.1 - 9.8e-20 69.4 0.7 2e-19 68.4 0.5 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 EIE75829.1 - 4.1e-08 32.9 0.0 9.4e-08 31.8 0.0 1.7 1 0 0 1 1 1 1 SLBB domain Peptidase_M1 PF01433.15 EIE75830.1 - 6.8e-138 459.9 2.9 4.6e-86 289.3 0.1 2.1 2 0 0 2 2 2 2 Peptidase family M1 ERAP1_C PF11838.3 EIE75830.1 - 1.2e-64 218.6 1.5 1.2e-64 218.6 1.1 1.8 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EIE75830.1 - 1e-18 67.6 0.5 2.4e-18 66.4 0.3 1.6 1 0 0 1 1 1 1 Peptidase MA superfamily UPF0121 PF03661.8 EIE75833.1 - 3.6e-18 65.6 5.1 4.8e-18 65.2 3.5 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) zf-H2C2_2 PF13465.1 EIE75835.1 - 7.3e-07 29.1 10.6 4.5e-06 26.6 2.6 2.7 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.21 EIE75835.1 - 0.00018 21.6 16.0 0.00055 20.1 4.8 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIE75835.1 - 0.0026 17.9 11.4 0.0051 17.0 3.7 2.7 2 0 0 2 2 2 1 C2H2-type zinc finger ECH_C PF13766.1 EIE75836.1 - 1.9e-20 73.1 0.0 4.7e-20 71.9 0.0 1.6 2 0 0 2 2 2 1 2-enoyl-CoA Hydratase C-terminal region DUF1639 PF07797.9 EIE75836.1 - 0.063 12.6 0.0 0.16 11.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1639) NST1 PF13945.1 EIE75837.1 - 0.27 11.2 5.4 0.3 11.1 3.7 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator BRF1 PF07741.8 EIE75837.1 - 0.59 10.3 5.7 0.87 9.8 4.0 1.2 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Med19 PF10278.4 EIE75837.1 - 4.7 6.8 14.5 6.9 6.3 10.0 1.3 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 DUF2838 PF10998.3 EIE75838.1 - 2.3e-35 120.8 6.8 2.3e-35 120.8 4.7 3.3 4 0 0 4 4 4 1 Protein of unknown function (DUF2838) ApoC-I PF04691.7 EIE75838.1 - 0.062 13.0 2.6 0.11 12.2 1.8 1.4 1 0 0 1 1 1 0 Apolipoprotein C-I (ApoC-1) Atg14 PF10186.4 EIE75838.1 - 0.091 11.6 0.3 0.12 11.2 0.2 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Choline_kinase PF01633.15 EIE75839.1 - 1.2e-53 181.8 0.5 2e-53 181.0 0.4 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 EIE75839.1 - 2.1e-06 27.6 0.0 3e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family CUE PF02845.11 EIE75840.1 - 1.3e-08 34.1 0.0 2.7e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 CUE domain DUF3697 PF12478.3 EIE75840.1 - 0.015 14.8 0.0 0.035 13.7 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-associated protein 2 NST1 PF13945.1 EIE75842.1 - 7.7e-13 48.9 0.3 7.7e-13 48.9 0.2 1.9 2 0 0 2 2 2 1 Salt tolerance down-regulator GEMIN8 PF15348.1 EIE75842.1 - 0.0094 16.0 3.1 0.012 15.6 2.1 1.1 1 0 0 1 1 1 1 Gemini of Cajal bodies-associated protein 8 Nop14 PF04147.7 EIE75842.1 - 0.022 12.6 12.2 0.02 12.8 8.4 1.0 1 0 0 1 1 1 0 Nop14-like family COPI_C PF06957.6 EIE75842.1 - 0.023 13.2 5.2 0.026 13.0 3.6 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Daxx PF03344.10 EIE75842.1 - 0.074 11.5 9.6 0.075 11.5 6.6 1.1 1 0 0 1 1 1 0 Daxx Family SDA1 PF05285.7 EIE75842.1 - 0.11 11.7 9.9 0.12 11.6 6.9 1.1 1 0 0 1 1 1 0 SDA1 Saw1 PF11561.3 EIE75842.1 - 0.12 11.7 6.3 0.013 14.9 1.6 1.4 1 1 1 2 2 2 0 Single strand annealing-weakened 1 ChaB PF06150.7 EIE75842.1 - 0.21 11.4 1.1 0.42 10.4 0.1 2.0 2 0 0 2 2 2 0 ChaB NOA36 PF06524.7 EIE75842.1 - 0.51 9.5 9.4 0.65 9.1 6.5 1.4 1 0 0 1 1 1 0 NOA36 protein DUF2722 PF10846.3 EIE75842.1 - 0.61 9.0 4.1 0.71 8.8 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Astro_capsid PF03115.9 EIE75842.1 - 1.1 7.4 6.1 1.2 7.3 4.2 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor FAM178 PF14816.1 EIE75842.1 - 1.2 7.7 5.0 1.4 7.5 3.4 1.2 1 0 0 1 1 1 0 Family of unknown function, FAM178 Mak16 PF04874.9 EIE75842.1 - 1.4 9.0 18.4 0.39 10.8 10.3 1.9 2 0 0 2 2 2 0 Mak16 protein C-terminal region TRAP_alpha PF03896.11 EIE75842.1 - 1.4 7.8 7.5 1.7 7.5 5.2 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DNA_pol_phi PF04931.8 EIE75842.1 - 3.6 5.2 18.3 4.2 5.0 12.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi Sigma70_ner PF04546.8 EIE75842.1 - 7.4 6.1 13.3 1.7 8.2 7.2 1.4 2 0 0 2 2 2 0 Sigma-70, non-essential region RasGEF PF00617.14 EIE75843.1 - 1.2e-33 116.3 2.9 1.5e-32 112.8 0.4 3.1 2 1 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 EIE75843.1 - 1e-08 35.2 6.0 1.8e-07 31.2 0.4 3.6 2 1 1 3 3 3 2 RasGEF N-terminal motif PNRC PF15365.1 EIE75843.1 - 0.017 15.1 0.5 0.088 12.8 0.3 2.3 1 0 0 1 1 1 0 Proline-rich nuclear receptor coactivator MHYT PF03707.11 EIE75845.1 - 4.2e-12 45.9 4.7 1.7e-07 31.2 0.3 2.7 2 0 0 2 2 2 2 Bacterial signalling protein N terminal repeat DUF2029 PF09594.5 EIE75845.1 - 0.00024 20.7 8.1 0.00035 20.1 5.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2029) 7TM_GPCR_Str PF10326.4 EIE75845.1 - 0.0057 15.8 0.8 0.011 14.8 0.6 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Str DUF1467 PF07330.7 EIE75845.1 - 0.035 13.8 0.1 0.035 13.8 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1467) Hpre_diP_synt_I PF07456.6 EIE75845.1 - 0.24 11.2 9.6 0.13 12.0 4.6 2.0 1 1 1 2 2 2 0 Heptaprenyl diphosphate synthase component I DUF4131 PF13567.1 EIE75845.1 - 1.2 8.4 11.6 9.4 5.6 6.3 2.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) Baculo_11_kDa PF06143.6 EIE75845.1 - 3 7.2 6.4 16 4.9 0.0 2.9 3 0 0 3 3 3 0 Baculovirus 11 kDa family Na_H_Exchanger PF00999.16 EIE75847.1 - 3.1e-62 210.2 29.9 3.6e-62 210.0 20.7 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF4191 PF13829.1 EIE75847.1 - 9.9 5.1 10.2 3.9 6.5 0.2 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4191) PLDc PF00614.17 EIE75848.1 - 2.2e-18 65.4 3.2 2.3e-11 43.1 0.2 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 EIE75848.1 - 1.6e-14 53.7 0.1 1.4e-06 28.0 0.0 3.3 3 0 0 3 3 3 3 PLD-like domain DYW_deaminase PF14432.1 EIE75848.1 - 0.12 12.3 0.0 0.31 11.0 0.0 1.7 1 0 0 1 1 1 0 DYW family of nucleic acid deaminases DUF1387 PF07139.6 EIE75849.1 - 0.032 13.8 1.9 0.12 11.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) Ribosomal_S15 PF00312.17 EIE75849.1 - 0.036 13.8 0.1 0.15 11.8 0.1 2.1 1 1 0 1 1 1 0 Ribosomal protein S15 Fe-S_assembly PF04384.8 EIE75849.1 - 0.054 13.8 0.3 0.1 13.0 0.2 1.5 1 0 0 1 1 1 0 Iron-sulphur cluster assembly YlqD PF11068.3 EIE75849.1 - 0.15 12.0 9.4 0.042 13.8 1.9 2.1 1 1 1 2 2 2 0 YlqD protein ETF_QO PF05187.8 EIE75850.1 - 5.2e-45 151.9 0.0 8.3e-45 151.2 0.0 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase DAO PF01266.19 EIE75850.1 - 2.1e-10 40.0 0.0 6.9e-05 21.9 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EIE75850.1 - 1.7e-09 37.0 0.5 4.5e-05 22.4 1.5 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EIE75850.1 - 7.8e-07 29.0 0.0 2.9e-06 27.1 0.0 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EIE75850.1 - 5.7e-06 26.3 0.0 9.6e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EIE75850.1 - 1.1e-05 24.6 0.0 0.00032 19.8 0.1 2.1 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.1 EIE75850.1 - 1.4e-05 24.9 0.3 4.3e-05 23.3 0.2 1.9 1 1 0 1 1 1 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 EIE75850.1 - 2.5e-05 23.5 0.1 4.9e-05 22.5 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EIE75850.1 - 7.5e-05 21.9 0.0 0.00016 20.8 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EIE75850.1 - 0.00013 22.3 0.3 0.17 12.2 0.3 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Fer4_7 PF12838.2 EIE75850.1 - 0.00014 22.1 1.3 0.00035 20.8 0.9 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain HI0933_like PF03486.9 EIE75850.1 - 0.00016 20.2 0.6 0.00026 19.5 0.4 1.3 1 0 0 1 1 1 1 HI0933-like protein Trp_halogenase PF04820.9 EIE75850.1 - 0.00069 18.3 0.0 0.004 15.8 0.2 1.9 2 0 0 2 2 2 1 Tryptophan halogenase Lycopene_cycl PF05834.7 EIE75850.1 - 0.00091 18.2 0.3 0.0013 17.7 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EIE75850.1 - 0.0049 16.9 0.2 0.012 15.7 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_10 PF13237.1 EIE75850.1 - 0.037 13.8 1.1 0.078 12.7 0.7 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain GIDA PF01134.17 EIE75850.1 - 0.055 12.3 0.6 0.079 11.8 0.4 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A HAD PF12710.2 EIE75851.1 - 7.6e-12 45.7 0.0 1e-11 45.3 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EIE75851.1 - 0.02 15.2 0.1 0.026 14.9 0.0 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 EIE75851.1 - 0.025 13.7 3.8 0.18 10.9 0.0 2.9 1 1 0 4 4 4 0 Putative Phosphatase Hydrolase_3 PF08282.7 EIE75851.1 - 0.029 13.9 0.6 1.1 8.8 0.0 2.1 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Ribosomal_L36e PF01158.13 EIE75852.1 - 1.1e-38 131.1 5.0 1.2e-38 131.0 3.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e LemA PF04011.7 EIE75852.1 - 0.0019 17.3 0.1 0.0019 17.3 0.1 1.1 1 0 0 1 1 1 1 LemA family 4HB_MCP_1 PF12729.2 EIE75852.1 - 0.014 14.7 0.1 0.017 14.4 0.0 1.1 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction priB_priC PF07445.7 EIE75852.1 - 0.052 13.0 0.1 0.058 12.8 0.0 1.1 1 0 0 1 1 1 0 Primosomal replication protein priB and priC zf-H2C2_2 PF13465.1 EIE75853.1 - 9.6e-07 28.7 9.7 5.9e-05 23.1 1.4 2.8 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EIE75853.1 - 0.00011 22.2 15.0 0.015 15.5 3.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_5 PF13909.1 EIE75853.1 - 0.0021 18.1 4.0 0.0021 18.1 2.8 3.1 3 0 0 3 3 3 1 C2H2-type zinc-finger domain zf-C2H2 PF00096.21 EIE75853.1 - 0.0025 18.0 16.9 0.23 11.8 4.0 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type Endonuclease_7 PF02945.10 EIE75853.1 - 0.15 11.7 5.5 0.28 10.9 3.8 1.4 1 0 0 1 1 1 0 Recombination endonuclease VII zf-Di19 PF05605.7 EIE75853.1 - 0.26 11.4 10.8 0.22 11.6 6.3 1.7 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 EIE75853.1 - 0.32 11.2 10.7 1.1 9.4 2.1 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EIE75853.1 - 2.5 8.4 7.7 0.15 12.3 0.9 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EIE75853.1 - 5.2 7.2 11.2 1.5 9.0 1.0 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF329 PF03884.9 EIE75853.1 - 9.9 5.8 8.9 1.9e+02 1.6 6.2 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF329) MRP-L27 PF09809.4 EIE75854.1 - 4.4e-22 77.8 0.2 4.7e-22 77.7 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 DUF3885 PF13021.1 EIE75855.1 - 0.14 11.8 0.3 0.31 10.7 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3885) ABC_tran PF00005.22 EIE75856.1 - 8.1e-16 58.5 0.0 2.5e-15 56.9 0.0 1.8 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EIE75856.1 - 1.1e-11 45.2 0.5 6.2e-05 23.0 0.0 2.2 1 1 1 2 2 2 2 AAA domain AAA_15 PF13175.1 EIE75856.1 - 3.7e-07 29.5 0.0 0.012 14.7 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 EIE75856.1 - 0.0046 16.2 0.0 1.3 8.1 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EIE75856.1 - 0.0046 16.4 0.0 0.009 15.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 EIE75856.1 - 0.005 16.0 0.0 0.0077 15.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 PduV-EutP PF10662.4 EIE75856.1 - 0.0071 15.8 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.1 EIE75856.1 - 0.0081 15.5 0.0 0.02 14.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EIE75856.1 - 0.0084 16.0 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF3584 PF12128.3 EIE75856.1 - 0.017 12.4 0.2 0.023 12.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_23 PF13476.1 EIE75856.1 - 0.019 15.2 0.0 0.044 14.1 0.0 1.5 2 0 0 2 2 1 0 AAA domain AAA_22 PF13401.1 EIE75856.1 - 0.02 15.0 0.2 0.071 13.2 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EIE75856.1 - 0.032 14.2 0.9 0.087 12.8 0.0 2.0 3 0 0 3 3 3 0 AAA ATPase domain Arf PF00025.16 EIE75856.1 - 0.034 13.3 0.2 0.086 12.0 0.0 1.6 2 0 0 2 2 2 0 ADP-ribosylation factor family Miro PF08477.8 EIE75856.1 - 0.036 14.5 0.0 0.088 13.3 0.0 1.8 2 0 0 2 2 2 0 Miro-like protein NACHT PF05729.7 EIE75856.1 - 0.038 13.6 0.1 0.07 12.7 0.1 1.4 1 0 0 1 1 1 0 NACHT domain AAA_17 PF13207.1 EIE75856.1 - 0.041 14.6 0.9 0.1 13.4 0.6 2.0 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EIE75856.1 - 0.055 13.3 0.1 0.2 11.5 0.0 1.9 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EIE75856.1 - 0.092 13.0 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_13 PF13166.1 EIE75856.1 - 0.096 11.1 0.0 0.14 10.6 0.0 1.1 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 EIE75856.1 - 0.097 12.1 0.0 0.22 10.9 0.0 1.5 2 0 0 2 2 1 0 CobW/HypB/UreG, nucleotide-binding domain UPF0079 PF02367.12 EIE75856.1 - 0.1 12.2 0.1 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 SRP54 PF00448.17 EIE75856.1 - 0.15 11.4 0.2 0.26 10.7 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Mito_carr PF00153.22 EIE75859.1 - 1.1e-70 233.3 4.0 2.5e-23 81.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Sel1 PF08238.7 EIE75860.1 - 2.5e-32 110.5 5.7 1.7e-06 28.4 0.0 7.2 7 0 0 7 7 7 5 Sel1 repeat TPR_12 PF13424.1 EIE75860.1 - 0.021 14.7 5.0 0.66 9.9 0.0 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 EIE75860.1 - 0.038 13.6 5.5 1.8 8.2 0.1 3.7 3 1 2 5 5 5 0 TPR repeat DUF2404 PF10296.4 EIE75861.1 - 7.1e-25 86.9 0.1 1.8e-24 85.6 0.0 1.7 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) PH PF00169.24 EIE75861.1 - 0.00052 20.1 0.1 0.0011 19.1 0.1 1.6 1 0 0 1 1 1 1 PH domain Sua5_yciO_yrdC PF01300.13 EIE75862.1 - 2.3e-56 189.8 0.0 3.3e-56 189.3 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 EIE75862.1 - 7.4e-29 100.3 0.0 1.2e-28 99.7 0.0 1.3 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding RGS PF00615.14 EIE75863.1 - 1.3e-05 25.3 0.0 3.5e-05 23.8 0.0 1.6 2 0 0 2 2 2 1 Regulator of G protein signaling domain Sec3-PIP2_bind PF15277.1 EIE75863.1 - 0.048 13.5 0.6 0.064 13.1 0.4 1.3 1 0 0 1 1 1 0 Exocyst complex component SEC3 N-terminal PIP2 binding PH RVT_1 PF00078.22 EIE75866.1 - 1.2e-30 106.4 0.0 1.9e-30 105.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) A_thal_3526 PF09713.5 EIE75866.1 - 0.1 12.7 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 Plant protein 1589 of unknown function (A_thal_3526) Zn_Tnp_IS1 PF03811.8 EIE75868.1 - 0.0019 17.6 0.7 0.0044 16.4 0.5 1.6 1 0 0 1 1 1 1 InsA N-terminal domain DUF2296 PF10058.4 EIE75868.1 - 0.0071 16.0 1.0 0.017 14.8 0.7 1.6 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) DUF4140 PF13600.1 EIE75868.1 - 0.027 14.9 1.4 0.027 14.9 1.0 2.3 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) Phlebovirus_NSM PF07246.6 EIE75868.1 - 0.056 12.5 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DivIC PF04977.10 EIE75868.1 - 0.075 12.5 1.1 0.23 10.9 0.7 1.8 1 0 0 1 1 1 0 Septum formation initiator ERM PF00769.14 EIE75868.1 - 0.1 12.1 3.7 0.14 11.7 1.3 2.0 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Cnl2_NKP2 PF09447.5 EIE75868.1 - 0.11 12.1 4.5 5.7 6.7 0.1 2.7 2 0 0 2 2 2 0 Cnl2/NKP2 family protein ADIP PF11559.3 EIE75868.1 - 0.18 11.7 6.5 0.22 11.4 1.3 2.5 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Zn_Tnp_IS1595 PF12760.2 EIE75868.1 - 0.22 11.3 0.9 0.46 10.3 0.7 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zinc_ribbon_4 PF13717.1 EIE75868.1 - 0.41 10.3 3.4 12 5.7 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EIE75868.1 - 0.61 9.7 3.5 14 5.4 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain TMF_TATA_bd PF12325.3 EIE75868.1 - 0.79 9.4 6.6 0.19 11.4 1.1 2.4 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding OEP PF02321.13 EIE75868.1 - 2.2 7.8 12.2 0.14 11.6 1.3 2.8 3 0 0 3 3 3 0 Outer membrane efflux protein DDE_3 PF13358.1 EIE75869.1 - 9.3e-28 96.8 0.0 2.5e-27 95.4 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease rve PF00665.21 EIE75869.1 - 0.011 15.8 0.0 0.021 14.9 0.0 1.4 1 0 0 1 1 1 0 Integrase core domain RVT_1 PF00078.22 EIE75871.1 - 3.8e-24 85.2 0.0 7.4e-24 84.2 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Methyltransf_23 PF13489.1 EIE75873.1 - 1.2e-13 51.0 0.0 2e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIE75873.1 - 1.6e-11 44.7 0.3 2.8e-10 40.7 0.1 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIE75873.1 - 1.1e-10 41.8 0.0 2.4e-10 40.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIE75873.1 - 1e-09 38.1 0.0 7.6e-09 35.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIE75873.1 - 1.1e-07 31.2 0.0 2.7e-07 29.9 0.0 1.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EIE75873.1 - 1.8e-07 31.4 0.0 5.6e-07 29.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIE75873.1 - 4.2e-07 30.3 0.0 1.3e-06 28.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EIE75873.1 - 5.5e-06 25.5 0.0 0.00012 21.2 0.0 2.3 2 1 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.14 EIE75873.1 - 0.00022 21.2 0.1 0.00036 20.5 0.1 1.5 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 EIE75873.1 - 0.00037 20.5 0.0 0.00088 19.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EIE75873.1 - 0.00057 19.5 0.0 0.00099 18.8 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase MTS PF05175.9 EIE75873.1 - 0.0018 17.6 0.0 0.0033 16.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain MetW PF07021.7 EIE75873.1 - 0.0041 16.5 0.0 0.0057 16.0 0.0 1.1 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW CheR PF01739.13 EIE75873.1 - 0.0066 15.7 0.0 0.015 14.5 0.0 1.6 2 0 0 2 2 2 1 CheR methyltransferase, SAM binding domain Methyltransf_PK PF05891.7 EIE75873.1 - 0.009 15.3 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_29 PF03141.11 EIE75873.1 - 0.012 13.9 0.0 0.022 13.0 0.0 1.4 1 1 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_9 PF08003.6 EIE75873.1 - 0.023 13.4 0.1 0.035 12.8 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) TehB PF03848.9 EIE75873.1 - 0.025 13.7 0.0 0.042 13.0 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_2 PF00891.13 EIE75873.1 - 0.032 13.4 0.0 0.065 12.4 0.0 1.5 1 1 0 1 1 1 0 O-methyltransferase CMAS PF02353.15 EIE75873.1 - 0.048 12.7 0.0 0.071 12.1 0.0 1.4 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase MFS_2 PF13347.1 EIE75874.1 - 7.8e-09 34.4 27.7 7.8e-09 34.4 19.2 2.2 2 1 0 2 2 2 1 MFS/sugar transport protein PUCC PF03209.10 EIE75874.1 - 1e-05 24.4 5.7 1.1e-05 24.4 1.1 2.2 2 0 0 2 2 2 1 PUCC protein Bap31 PF05529.7 EIE75874.1 - 0.066 12.6 0.1 2.9 7.3 0.0 2.5 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like Shisa PF13908.1 EIE75874.1 - 0.28 11.3 1.1 1.9 8.6 0.2 2.3 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator DUF3169 PF11368.3 EIE75874.1 - 6.8 5.8 11.9 0.11 11.7 1.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3169) DUF962 PF06127.6 EIE75874.1 - 9.8 6.1 9.5 2.4 8.1 0.4 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF962) BTG PF07742.7 EIE75876.1 - 3.2e-31 107.3 0.0 3.8e-31 107.0 0.0 1.1 1 0 0 1 1 1 1 BTG family Mycoplasma_p37 PF06646.6 EIE75876.1 - 0.012 14.6 0.0 0.017 14.1 0.0 1.1 1 0 0 1 1 1 0 High affinity transport system protein p37 zf-CDGSH PF09360.5 EIE75877.1 - 3.8e-11 42.6 8.5 1.5e-06 27.8 0.5 3.1 2 1 1 3 3 3 2 Iron-binding zinc finger CDGSH type rve PF00665.21 EIE75880.1 - 0.013 15.6 0.0 0.017 15.2 0.0 1.2 1 0 0 1 1 1 0 Integrase core domain Methyltransf_28 PF02636.12 EIE75883.1 - 6.7e-33 114.1 0.0 2.4e-24 86.1 0.0 2.2 1 1 1 2 2 2 2 Putative S-adenosyl-L-methionine-dependent methyltransferase PRMT5 PF05185.11 EIE75883.1 - 0.062 12.2 0.5 0.1 11.5 0.0 1.6 2 0 0 2 2 2 0 PRMT5 arginine-N-methyltransferase Methyltransf_12 PF08242.7 EIE75883.1 - 0.068 13.6 0.0 0.15 12.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain RabGAP-TBC PF00566.13 EIE75884.1 - 7.5e-47 159.5 0.2 7.5e-47 159.5 0.2 2.7 2 1 1 3 3 3 1 Rab-GTPase-TBC domain CDC37_N PF03234.9 EIE75884.1 - 0.022 15.0 6.2 0.021 15.1 3.3 1.6 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding zf-C2H2 PF00096.21 EIE75885.1 - 6.7e-07 29.2 14.4 0.00042 20.4 1.6 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIE75885.1 - 3.9e-06 26.8 11.1 0.014 15.7 1.9 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EIE75885.1 - 6.3e-05 23.0 17.6 0.00062 19.9 2.5 3.6 3 0 0 3 3 3 2 Zinc-finger double domain Ada_Zn_binding PF02805.11 EIE75885.1 - 0.069 12.7 0.4 1.6 8.4 0.0 2.3 1 1 1 2 2 2 0 Metal binding domain of Ada zf-met PF12874.2 EIE75885.1 - 0.078 13.2 3.6 0.9 9.8 0.2 2.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type CHORD PF04968.7 EIE75885.1 - 0.29 11.4 4.8 1.8 8.8 1.1 2.4 1 1 1 2 2 2 0 CHORD DUF605 PF04652.11 EIE75885.1 - 1.4 8.2 11.4 1.9 7.7 7.9 1.2 1 0 0 1 1 1 0 Vta1 like DUF1679 PF07914.6 EIE75886.1 - 0.015 13.9 0.1 0.64 8.5 0.0 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1679) Ribosomal_L22 PF00237.14 EIE75886.1 - 0.06 13.3 0.8 0.1 12.5 0.5 1.4 1 0 0 1 1 1 0 Ribosomal protein L22p/L17e EF-hand_4 PF12763.2 EIE75888.1 - 0.012 15.3 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand TC1 PF15063.1 EIE75888.1 - 0.047 13.2 0.1 0.13 11.7 0.0 1.8 2 1 0 2 2 2 0 Thyroid cancer protein 1 EF-hand_7 PF13499.1 EIE75888.1 - 0.088 12.9 0.0 0.18 11.9 0.0 1.6 1 1 0 1 1 1 0 EF-hand domain pair DUF3221 PF11518.3 EIE75889.1 - 0.077 12.6 1.5 0.15 11.7 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3221) zf-CCHC PF00098.18 EIE75891.1 - 5.6e-07 29.1 13.2 0.00018 21.2 0.2 2.3 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 EIE75891.1 - 0.0037 16.8 7.8 0.094 12.3 0.4 2.4 2 0 0 2 2 2 2 Zinc knuckle RVT_1 PF00078.22 EIE75892.1 - 1.7e-19 70.0 0.0 9.8e-18 64.2 0.0 2.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RRM_1 PF00076.17 EIE75893.1 - 0.043 13.4 0.1 5.3 6.7 0.0 3.0 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.18 EIE75893.1 - 0.053 13.4 6.2 0.083 12.8 4.3 1.3 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.22 EIE75895.1 - 7.9e-29 100.5 0.0 1.5e-28 99.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.1 EIE75895.1 - 1.1e-09 38.4 0.3 2.7e-09 37.2 0.2 1.7 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase DUF446 PF04287.7 EIE75895.1 - 0.052 13.3 0.0 0.18 11.5 0.0 1.9 1 0 0 1 1 1 0 tRNA pseudouridine synthase C Slx4 PF09494.5 EIE75895.1 - 0.1 12.3 0.0 0.28 10.9 0.0 1.8 1 0 0 1 1 1 0 Slx4 endonuclease DUF770 PF05591.7 EIE75896.1 - 0.0045 16.5 1.1 0.0074 15.8 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF770) YebO PF13974.1 EIE75896.1 - 0.027 14.2 7.7 0.97 9.2 0.0 2.4 2 0 0 2 2 2 0 YebO-like protein DUF2140 PF09911.4 EIE75896.1 - 0.088 11.9 1.2 0.14 11.3 0.8 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) FKBP_N PF01346.13 EIE75896.1 - 0.099 12.6 3.7 0.11 12.5 1.1 1.9 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase CRAL_TRIO PF00650.15 EIE75897.1 - 1.7e-13 50.3 0.5 4e-13 49.1 0.1 1.8 2 0 0 2 2 2 1 CRAL/TRIO domain RhoGEF PF00621.15 EIE75898.1 - 1.4e-28 99.9 0.7 2.6e-28 99.1 0.5 1.4 1 0 0 1 1 1 1 RhoGEF domain PB1 PF00564.19 EIE75898.1 - 2.2e-12 46.4 0.1 3e-11 42.8 0.0 2.5 2 0 0 2 2 2 1 PB1 domain PH_10 PF15411.1 EIE75898.1 - 6.6e-10 39.2 5.9 9.3e-07 29.0 0.6 2.7 1 1 1 2 2 2 2 Pleckstrin homology domain Aa_trans PF01490.13 EIE75899.1 - 3.3e-11 42.3 0.5 3.7e-11 42.1 0.3 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Myb_DNA-bind_6 PF13921.1 EIE75900.1 - 6.1e-05 23.0 0.2 0.00016 21.7 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EIE75900.1 - 0.016 15.2 0.1 0.029 14.4 0.1 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain DUF2580 PF10824.3 EIE75901.1 - 0.073 13.4 0.3 0.28 11.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2580) FGF PF00167.13 EIE75902.1 - 0.00079 19.1 0.1 0.00088 19.0 0.1 1.1 1 0 0 1 1 1 1 Fibroblast growth factor Imm13 PF15564.1 EIE75902.1 - 0.052 13.2 0.0 0.062 13.0 0.0 1.1 1 0 0 1 1 1 0 Immunity protein 13 SARG PF15385.1 EIE75903.1 - 0.044 13.1 2.4 0.05 12.9 1.7 1.1 1 0 0 1 1 1 0 Specifically androgen-regulated gene protein VSP PF03302.8 EIE75903.1 - 0.12 11.0 0.5 0.15 10.6 0.3 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein MUG2_C PF08593.5 EIE75905.1 - 0.086 13.0 0.2 0.093 12.9 0.1 1.0 1 0 0 1 1 1 0 Meiotically up-regulated glycoproteins C-terminal DASH_Dam1 PF08653.5 EIE75906.1 - 2.3e-07 30.4 0.0 3.4e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 DASH complex subunit Dam1 HTH_IclR PF09339.5 EIE75906.1 - 0.0012 18.4 0.0 0.002 17.6 0.0 1.3 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_24 PF13412.1 EIE75906.1 - 0.0098 15.2 0.1 0.045 13.1 0.0 2.0 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding TrmB PF01978.14 EIE75906.1 - 0.085 12.5 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_9 PF08221.6 EIE75906.1 - 0.11 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain RasGAP PF00616.14 EIE75907.1 - 1.3e-29 103.2 1.2 1.2e-28 100.1 0.1 2.9 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.1 EIE75907.1 - 4.1e-19 68.9 1.5 2.9e-18 66.1 1.0 2.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.15 EIE75907.1 - 0.0023 17.4 0.3 0.008 15.6 0.2 2.0 1 0 0 1 1 1 1 CRAL/TRIO domain Sugar_tr PF00083.19 EIE75908.1 - 1.2e-80 271.3 21.5 1e-76 258.3 9.3 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EIE75908.1 - 2.8e-22 78.9 27.9 5.2e-21 74.7 12.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily CorA PF01544.13 EIE75908.1 - 0.73 8.8 3.9 2 7.3 2.7 1.6 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein COPI_assoc PF08507.5 EIE75909.1 - 0.0036 16.9 7.4 0.014 15.1 5.0 1.8 1 1 1 2 2 2 1 COPI associated protein PspB PF06667.7 EIE75909.1 - 0.14 12.1 0.1 0.26 11.2 0.1 1.5 1 0 0 1 1 1 0 Phage shock protein B Fijivirus_P9-2 PF06837.6 EIE75909.1 - 0.21 10.7 4.4 0.29 10.2 3.1 1.3 1 1 0 1 1 1 0 Fijivirus P9-2 protein MVIN PF03023.9 EIE75909.1 - 0.72 8.2 9.6 1.1 7.6 6.6 1.4 1 1 0 1 1 1 0 MviN-like protein Enkurin PF13864.1 EIE75910.1 - 0.0024 18.0 8.8 0.0063 16.6 6.1 1.8 1 1 0 1 1 1 1 Calmodulin-binding Cyt-b5 PF00173.23 EIE75911.1 - 0.035 13.9 0.0 0.067 13.0 0.0 1.5 1 0 0 1 1 1 0 Cytochrome b5-like Heme/Steroid binding domain Sec20 PF03908.8 EIE75911.1 - 4 7.1 10.1 0.18 11.5 2.0 2.5 2 1 0 2 2 2 0 Sec20 FAM110_C PF14160.1 EIE75911.1 - 7.5 7.5 14.7 0.11 13.4 1.4 2.7 2 1 0 2 2 2 0 Centrosome-associated C terminus DUF3347 PF11827.3 EIE75911.1 - 8.5 6.3 16.5 0.63 10.0 2.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3347) DUF3535 PF12054.3 EIE75912.1 - 0.0076 14.9 0.1 0.0087 14.7 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3535) DDE_1 PF03184.14 EIE75913.1 - 4.4e-14 52.1 0.0 7.5e-14 51.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease THOC7 PF05615.8 EIE75913.1 - 0.13 12.5 0.4 0.3 11.3 0.3 1.6 1 1 0 1 1 1 0 Tho complex subunit 7 Abhydrolase_2 PF02230.11 EIE75916.1 - 2.3e-66 223.3 0.0 2.7e-66 223.1 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EIE75916.1 - 2.4e-12 46.8 0.0 3.3e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIE75916.1 - 2.1e-09 37.5 0.0 0.0022 17.8 0.0 2.5 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EIE75916.1 - 7.5e-07 28.5 0.9 5.1e-06 25.8 0.0 2.4 2 1 1 3 3 3 1 Prolyl oligopeptidase family FSH1 PF03959.8 EIE75916.1 - 7.2e-06 25.6 0.0 2.1e-05 24.1 0.0 1.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.13 EIE75916.1 - 6.3e-05 22.3 0.0 0.0001 21.6 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_4 PF08386.5 EIE75916.1 - 0.00012 21.9 0.0 0.00018 21.3 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_3 PF07859.8 EIE75916.1 - 0.00092 18.8 0.0 0.2 11.1 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EIE75916.1 - 0.016 15.0 0.0 3.7 7.4 0.0 2.3 2 0 0 2 2 2 0 Putative lysophospholipase Abhydrolase_1 PF00561.15 EIE75916.1 - 0.026 14.0 0.1 0.43 10.0 0.0 2.1 1 1 1 2 2 2 0 alpha/beta hydrolase fold Esterase_phd PF10503.4 EIE75916.1 - 0.16 11.1 0.0 15 4.7 0.0 2.2 1 1 1 2 2 2 0 Esterase PHB depolymerase Proteasome PF00227.21 EIE75917.1 - 1.2e-33 116.0 0.0 1.3e-33 115.8 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Cullin_Nedd8 PF10557.4 EIE75917.1 - 0.18 11.6 0.6 0.51 10.2 0.1 2.0 2 0 0 2 2 2 0 Cullin protein neddylation domain Phage_AlpA PF05930.7 EIE75918.1 - 0.033 13.9 0.0 0.058 13.1 0.0 1.5 1 0 0 1 1 1 0 Prophage CP4-57 regulatory protein (AlpA) DUF390 PF04094.9 EIE75919.1 - 0.077 11.0 0.1 0.091 10.7 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF390) bZIP_2 PF07716.10 EIE75919.1 - 4.2 7.2 6.2 0.7 9.7 1.2 2.0 2 1 0 2 2 2 0 Basic region leucine zipper RNase_HII PF01351.13 EIE75920.1 - 1.1e-44 152.5 0.0 1.2e-44 152.3 0.0 1.0 1 0 0 1 1 1 1 Ribonuclease HII FA_hydroxylase PF04116.8 EIE75922.1 - 3.9e-14 53.0 22.3 3.9e-14 53.0 15.4 2.0 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily PPTA PF01239.17 EIE75923.1 - 1.9e-35 118.7 19.3 1.1e-11 43.4 0.1 4.8 5 0 0 5 5 5 4 Protein prenyltransferase alpha subunit repeat FOP_dimer PF09398.5 EIE75923.1 - 0.019 14.9 0.1 1.6 8.7 0.0 3.1 2 1 1 3 3 3 0 FOP N terminal dimerisation domain Metallophos PF00149.23 EIE75924.1 - 1.4e-41 142.1 0.1 2e-41 141.6 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase zf-C2H2 PF00096.21 EIE75925.1 - 1.4e-13 50.2 12.6 3.7e-07 30.1 2.9 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIE75925.1 - 5.2e-12 45.4 10.8 1.3e-09 37.9 1.6 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EIE75925.1 - 7.5e-11 41.5 8.6 5.1e-06 26.4 1.6 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EIE75925.1 - 2.8e-05 24.1 8.1 0.00058 19.9 0.4 2.5 3 0 0 3 3 2 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 EIE75925.1 - 6.1e-05 23.0 3.0 0.00011 22.1 2.1 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 EIE75925.1 - 0.0015 18.6 5.9 0.085 12.9 0.7 2.3 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-BED PF02892.10 EIE75925.1 - 0.0053 16.4 8.6 0.04 13.6 1.2 2.4 1 1 1 2 2 2 1 BED zinc finger zf-C2HC_2 PF13913.1 EIE75925.1 - 0.042 13.5 9.8 0.13 12.0 0.9 2.5 2 1 0 2 2 2 0 zinc-finger of a C2HC-type PyrI_C PF02748.10 EIE75925.1 - 0.055 12.9 0.5 0.055 12.9 0.4 2.3 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-met PF12874.2 EIE75925.1 - 0.07 13.3 8.1 0.22 11.7 0.3 2.7 3 0 0 3 3 2 0 Zinc-finger of C2H2 type GAGA PF09237.6 EIE75925.1 - 0.084 12.4 1.1 0.17 11.4 0.7 1.6 1 1 0 1 1 1 0 GAGA factor zf-H2C2_5 PF13909.1 EIE75925.1 - 0.085 13.1 0.8 0.085 13.1 0.6 3.0 2 1 0 2 2 2 0 C2H2-type zinc-finger domain zf-FCS PF06467.9 EIE75925.1 - 0.1 12.2 0.2 0.1 12.2 0.2 2.4 1 1 1 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zinc_ribbon_4 PF13717.1 EIE75925.1 - 0.42 10.3 6.0 6.5 6.5 0.7 2.5 2 1 0 2 2 2 0 zinc-ribbon domain Rad50_zn_hook PF04423.9 EIE75925.1 - 0.58 9.6 5.6 8.1 5.9 0.1 2.3 1 1 1 2 2 2 0 Rad50 zinc hook motif zinc_ribbon_5 PF13719.1 EIE75925.1 - 0.66 9.6 6.1 7.4 6.2 0.7 2.5 2 1 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.1 EIE75925.1 - 0.89 9.5 8.5 4.1 7.4 0.2 2.7 2 1 0 2 2 2 0 C2H2-type zinc finger DUF2225 PF09986.4 EIE75925.1 - 1.5 8.2 5.2 4 6.8 0.5 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-AN1 PF01428.11 EIE75925.1 - 3.6 7.5 11.1 0.74 9.7 1.4 2.4 1 1 1 2 2 2 0 AN1-like Zinc finger DUF629 PF04780.7 EIE75925.1 - 3.7 5.9 5.6 7.6 4.9 0.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF629) Zn-ribbon_8 PF09723.5 EIE75925.1 - 5.9 6.9 9.8 7.5 6.5 5.2 2.2 2 1 0 2 2 2 0 Zinc ribbon domain Zn_Tnp_IS1 PF03811.8 EIE75925.1 - 6.8 6.2 11.1 1.4 8.5 1.7 2.7 2 1 0 2 2 2 0 InsA N-terminal domain ABC_tran PF00005.22 EIE75926.1 - 7.6e-14 52.1 0.0 8.4e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 ABC transporter UPF0079 PF02367.12 EIE75926.1 - 5.1e-06 26.1 0.0 6.7e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_19 PF13245.1 EIE75926.1 - 1.8e-05 24.3 0.0 2.7e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 EIE75926.1 - 7.2e-05 22.8 0.0 8.3e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.1 EIE75926.1 - 0.00011 22.6 0.0 0.00014 22.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EIE75926.1 - 0.00037 19.7 0.0 0.00037 19.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EIE75926.1 - 0.00042 19.7 0.0 0.00061 19.2 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EIE75926.1 - 0.00056 20.0 0.0 0.00064 19.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EIE75926.1 - 0.00086 18.9 0.0 0.0014 18.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 EIE75926.1 - 0.0024 16.6 0.0 0.003 16.3 0.0 1.1 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 EIE75926.1 - 0.0037 18.0 0.0 0.0046 17.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EIE75926.1 - 0.0044 16.6 0.0 0.0059 16.2 0.0 1.2 1 0 0 1 1 1 1 NACHT domain AAA_15 PF13175.1 EIE75926.1 - 0.0046 16.0 0.0 0.0046 16.0 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.16 EIE75926.1 - 0.0053 15.9 0.0 0.0058 15.8 0.0 1.1 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 EIE75926.1 - 0.0073 16.1 0.1 0.0077 16.1 0.1 1.3 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EIE75926.1 - 0.01 15.5 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase AAA_25 PF13481.1 EIE75926.1 - 0.019 14.3 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EIE75926.1 - 0.024 14.5 0.0 0.034 14.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 EIE75926.1 - 0.025 14.0 0.0 0.032 13.6 0.0 1.1 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_21 PF13304.1 EIE75926.1 - 0.028 14.3 0.0 0.034 14.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EIE75926.1 - 0.035 14.4 0.0 0.038 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 EIE75926.1 - 0.04 12.8 0.0 0.048 12.5 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_5 PF07728.9 EIE75926.1 - 0.047 13.4 0.0 0.074 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 EIE75926.1 - 0.059 13.3 0.1 0.078 12.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EIE75926.1 - 0.077 12.0 0.0 0.1 11.6 0.0 1.1 1 0 0 1 1 1 0 Zeta toxin AAA PF00004.24 EIE75926.1 - 0.098 12.8 0.0 0.098 12.8 0.0 1.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CPT PF07931.7 EIE75926.1 - 0.13 11.9 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein IstB_IS21 PF01695.12 EIE75926.1 - 0.15 11.5 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein DASH_Dam1 PF08653.5 EIE75928.1 - 2.1e-07 30.5 0.0 3.5e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 DASH complex subunit Dam1 HTH_IclR PF09339.5 EIE75928.1 - 0.0023 17.4 0.0 0.0042 16.6 0.0 1.3 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_24 PF13412.1 EIE75928.1 - 0.027 13.8 0.1 0.099 12.0 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Phage_integrase PF00589.17 EIE75930.1 - 1.4e-08 34.6 0.2 2e-08 34.0 0.2 1.3 1 0 0 1 1 1 1 Phage integrase family RRM_1 PF00076.17 EIE75931.1 - 3e-83 273.4 3.5 1.1e-17 63.4 0.0 5.7 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE75931.1 - 8.4e-68 224.3 0.3 2.2e-14 53.1 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE75931.1 - 2.1e-34 117.1 0.6 2.3e-06 27.3 0.2 5.6 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MutL_C PF08676.6 EIE75931.1 - 0.07 12.7 0.0 0.32 10.6 0.0 2.1 2 0 0 2 2 2 0 MutL C terminal dimerisation domain RRM_2 PF04059.7 EIE75931.1 - 0.078 12.9 0.6 5.2 7.1 0.0 3.9 6 0 0 6 6 6 0 RNA recognition motif 2 Cript PF10235.4 EIE75932.1 - 0.1 12.9 1.6 0.23 11.8 1.1 1.6 1 1 0 1 1 1 0 Microtubule-associated protein CRIPT DDE_3 PF13358.1 EIE75933.1 - 3.4e-19 69.0 0.1 2.3e-17 63.0 0.0 2.3 1 1 1 2 2 2 2 DDE superfamily endonuclease rve PF00665.21 EIE75933.1 - 0.035 14.2 0.0 0.11 12.5 0.0 1.9 1 1 0 1 1 1 0 Integrase core domain RabGAP-TBC PF00566.13 EIE75935.1 - 4.2e-59 199.5 4.6 4.3e-59 199.5 0.1 2.3 2 0 0 2 2 2 1 Rab-GTPase-TBC domain DUF4201 PF13870.1 EIE75935.1 - 0.012 15.0 22.7 0.31 10.4 7.5 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) IncA PF04156.9 EIE75935.1 - 0.06 12.9 24.1 0.58 9.7 16.7 2.2 1 1 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 EIE75935.1 - 0.067 11.0 9.1 0.1 10.4 6.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family JmjC PF02373.17 EIE75935.1 - 0.078 13.2 0.7 0.16 12.1 0.1 1.9 2 0 0 2 2 1 0 JmjC domain, hydroxylase CALCOCO1 PF07888.6 EIE75935.1 - 0.1 10.8 17.2 0.15 10.3 12.0 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like RPA_C PF08784.6 EIE75935.1 - 0.1 13.0 1.8 0.4 11.1 1.2 2.0 2 0 0 2 2 1 0 Replication protein A C terminal Myosin_tail_1 PF01576.14 EIE75935.1 - 0.15 9.7 22.3 3.4 5.2 15.5 2.1 1 1 0 1 1 1 0 Myosin tail Hemerythrin PF01814.18 EIE75935.1 - 0.17 12.0 3.8 1.6 8.9 0.3 3.3 3 1 0 3 3 3 0 Hemerythrin HHE cation binding domain DUF972 PF06156.8 EIE75935.1 - 0.26 11.6 21.1 0.29 11.5 5.0 3.2 2 1 2 4 4 4 0 Protein of unknown function (DUF972) DUF4164 PF13747.1 EIE75935.1 - 0.31 11.1 12.7 1.4 9.0 4.5 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) Reo_sigmaC PF04582.7 EIE75935.1 - 0.33 10.0 5.9 0.62 9.1 4.1 1.4 1 1 0 1 1 1 0 Reovirus sigma C capsid protein DUF948 PF06103.6 EIE75935.1 - 0.44 10.4 9.9 2.6 7.9 5.9 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Peptidase_C6 PF00851.13 EIE75935.1 - 0.47 9.0 5.5 0.7 8.4 3.8 1.2 1 0 0 1 1 1 0 Helper component proteinase Baculo_PEP_C PF04513.7 EIE75935.1 - 0.47 10.2 6.8 1.6 8.5 4.3 2.1 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc24 PF08286.6 EIE75935.1 - 1.6 8.4 23.1 0.038 13.6 6.2 2.8 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 DUF1664 PF07889.7 EIE75935.1 - 2.2 8.1 9.3 0.31 10.8 3.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) APG6 PF04111.7 EIE75935.1 - 2.2 7.2 24.3 0.35 9.8 9.9 2.3 1 1 1 2 2 2 0 Autophagy protein Apg6 ADIP PF11559.3 EIE75935.1 - 2.4 8.0 30.6 0.061 13.2 9.5 2.9 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding ATG16 PF08614.6 EIE75935.1 - 2.7 7.7 29.7 0.04 13.7 13.2 2.9 3 1 1 4 4 3 0 Autophagy protein 16 (ATG16) Nup54 PF13874.1 EIE75935.1 - 3.3 7.3 22.1 0.026 14.1 7.6 2.6 2 1 1 3 3 3 0 Nucleoporin complex subunit 54 CCDC155 PF14662.1 EIE75935.1 - 6.9 6.2 27.9 0.49 9.9 14.3 2.5 3 0 0 3 3 3 0 Coiled-coil region of CCDC155 Tropomyosin_1 PF12718.2 EIE75935.1 - 7.9 6.3 26.1 0.92 9.3 8.3 2.5 1 1 1 2 2 2 0 Tropomyosin like DivIVA PF05103.8 EIE75935.1 - 10 6.2 18.7 0.34 10.9 1.9 3.5 3 0 0 3 3 3 0 DivIVA protein WD40 PF00400.27 EIE75936.1 - 6.9e-28 95.4 11.4 3.8e-11 42.4 0.2 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat DUF979 PF06166.7 EIE75937.1 - 0.054 12.4 0.1 0.054 12.4 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF979) SoxE PF06525.6 EIE75937.1 - 0.26 10.5 9.1 0.3 10.3 6.3 1.2 1 0 0 1 1 1 0 Sulfocyanin (SoxE) DUF2217 PF10265.4 EIE75937.1 - 0.51 9.0 7.1 0.55 8.9 4.9 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DUF822 PF05687.8 EIE75937.1 - 0.75 10.1 6.4 0.88 9.9 4.4 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF822) RAP1 PF07218.6 EIE75937.1 - 2.2 6.2 13.5 2.4 6.1 9.4 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DNA_pol_viral_N PF00242.12 EIE75937.1 - 3.1 6.7 6.7 3.3 6.6 4.6 1.0 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Steroid_dh PF02544.11 EIE75938.1 - 4.6e-12 45.9 0.4 6.6e-12 45.4 0.3 1.2 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase RRM_1 PF00076.17 EIE75939.1 - 7e-19 67.2 0.1 1e-18 66.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE75939.1 - 3.4e-13 49.2 0.0 4.4e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE75939.1 - 1.2e-12 47.6 0.0 1.8e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EIE75939.1 - 5.7e-05 22.9 0.0 7.5e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 RNA binding motif DDE_3 PF13358.1 EIE75941.1 - 1e-28 99.9 0.0 2.3e-28 98.7 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.14 EIE75941.1 - 0.0075 15.4 0.1 0.018 14.2 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease rve PF00665.21 EIE75941.1 - 0.063 13.3 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain FliT PF05400.8 EIE75941.1 - 0.17 12.3 0.4 0.17 12.3 0.3 2.6 3 0 0 3 3 3 0 Flagellar protein FliT DUF234 PF03008.9 EIE75942.1 - 0.057 13.5 1.4 0.21 11.7 1.0 1.8 1 1 0 1 1 1 0 Archaea bacterial proteins of unknown function A2M_recep PF07677.9 EIE75942.1 - 0.15 12.2 0.1 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 A-macroglobulin receptor Med13_C PF06333.7 EIE75943.1 - 2.2e-35 122.0 0.5 2.2e-35 122.0 0.3 2.7 3 0 0 3 3 3 1 Mediator complex subunit 13 C-terminal LUC7 PF03194.10 EIE75944.1 - 0.14 11.6 0.9 0.17 11.3 0.6 1.2 1 0 0 1 1 1 0 LUC7 N_terminus SET PF00856.23 EIE75945.1 - 1.1e-16 61.5 0.0 1.7e-16 60.9 0.0 1.3 1 0 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.6 EIE75945.1 - 0.00064 19.6 0.1 0.0052 16.6 0.0 2.4 3 0 0 3 3 3 1 Rubisco LSMT substrate-binding SRPRB PF09439.5 EIE75946.1 - 1.5e-06 27.5 0.1 1.7e-06 27.3 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit DUF3753 PF12575.3 EIE75946.1 - 0.19 11.5 3.2 0.2 11.4 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) MFS_2 PF13347.1 EIE75947.1 - 1.7e-07 30.0 30.5 1.4e-06 27.0 21.1 2.3 1 1 0 1 1 1 1 MFS/sugar transport protein Cad PF03596.8 EIE75947.1 - 0.019 14.7 3.3 0.05 13.2 0.1 2.6 2 0 0 2 2 2 0 Cadmium resistance transporter DUF533 PF04391.7 EIE75947.1 - 0.079 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF533) eIF3_N PF09440.5 EIE75948.1 - 6.3e-44 149.3 7.1 6.3e-44 149.3 4.9 2.7 3 0 0 3 3 3 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 EIE75948.1 - 8.9e-16 58.1 0.4 2.5e-14 53.4 0.1 2.7 2 0 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 EIE75948.1 - 0.0045 16.7 1.8 0.013 15.2 0.2 2.4 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 RPN7 PF10602.4 EIE75948.1 - 0.019 14.3 0.4 0.12 11.7 0.0 2.1 1 1 1 2 2 2 0 26S proteasome subunit RPN7 B3 PF02362.16 EIE75948.1 - 0.04 13.5 0.0 0.098 12.3 0.0 1.6 1 0 0 1 1 1 0 B3 DNA binding domain DUF771 PF05595.6 EIE75948.1 - 0.089 12.7 0.2 0.089 12.7 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF771) XhlA PF10779.4 EIE75948.1 - 2.4 8.1 0.0 2.4 8.1 0.0 3.4 4 0 0 4 4 4 0 Haemolysin XhlA PIF1 PF05970.9 EIE75949.1 - 4.1e-110 368.1 0.0 5.8e-110 367.6 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.1 EIE75949.1 - 2.6e-65 219.6 0.1 5.8e-65 218.4 0.0 1.7 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.1 EIE75949.1 - 2.2e-05 24.1 0.0 9.4e-05 22.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain Herpes_Helicase PF02689.9 EIE75949.1 - 3.2e-05 21.8 0.0 5.5e-05 21.1 0.0 1.3 1 0 0 1 1 1 1 Helicase ResIII PF04851.10 EIE75949.1 - 0.00035 20.4 0.0 0.0011 18.7 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EIE75949.1 - 0.00046 19.8 0.0 0.0013 18.4 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 EIE75949.1 - 0.0085 15.8 0.0 0.024 14.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TrwB_AAD_bind PF10412.4 EIE75949.1 - 0.047 12.2 0.0 0.077 11.6 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain T2SE PF00437.15 EIE75949.1 - 0.048 12.5 0.0 0.083 11.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.1 EIE75949.1 - 0.049 13.6 0.0 0.23 11.4 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain PhoH PF02562.11 EIE75949.1 - 0.072 12.3 0.0 0.15 11.2 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein UvrD_C_2 PF13538.1 EIE75949.1 - 0.081 13.0 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain DAP3 PF10236.4 EIE75949.1 - 0.09 11.6 0.0 0.17 10.7 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Acyltransferase PF01553.16 EIE75950.1 - 2.3e-35 120.9 0.1 3.8e-35 120.2 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Pkinase PF00069.20 EIE75951.1 - 3.6e-58 196.7 0.2 7e-57 192.5 0.2 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE75951.1 - 4.2e-31 107.9 0.0 4.6e-30 104.5 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase NDK PF00334.14 EIE75951.1 - 1.2e-11 44.5 0.0 2.3e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Kinase-like PF14531.1 EIE75951.1 - 6.3e-08 31.9 0.0 9.8e-08 31.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EIE75951.1 - 0.044 12.8 0.0 0.098 11.7 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIE75951.1 - 0.11 12.2 0.1 0.17 11.5 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Peptidase_A22B PF04258.8 EIE75952.1 - 2.8e-35 122.1 7.6 2.6e-32 112.4 1.3 2.1 1 1 1 2 2 2 2 Signal peptide peptidase GATA PF00320.22 EIE75953.1 - 3.2e-16 58.3 1.0 7.7e-16 57.1 0.7 1.6 1 0 0 1 1 1 1 GATA zinc finger eIF-5_eIF-2B PF01873.12 EIE75953.1 - 0.037 13.6 0.4 0.056 13.1 0.3 1.3 1 0 0 1 1 1 0 Domain found in IF2B/IF5 Homez PF11569.3 EIE75953.1 - 1 8.4 4.4 27 3.9 3.1 2.4 1 1 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez zf-RING_5 PF14634.1 EIE75953.1 - 3.9 7.2 7.4 1.4 8.7 3.0 1.9 2 1 0 2 2 2 0 zinc-RING finger domain DUF382 PF04037.8 EIE75954.1 - 2.1e-59 198.9 0.4 2.1e-59 198.9 0.3 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.11 EIE75954.1 - 3.2e-22 77.6 8.8 6.5e-22 76.6 6.1 1.6 1 0 0 1 1 1 1 PSP Peptidase_M20 PF01546.23 EIE75957.1 - 3e-07 30.1 0.0 3e-07 30.1 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 RasGEF_N_2 PF14663.1 EIE75957.1 - 0.023 14.6 0.9 0.054 13.4 0.4 1.7 1 1 0 1 1 1 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain C4 PF01413.14 EIE75957.1 - 0.09 12.6 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 C-terminal tandem repeated domain in type 4 procollagen Peptidase_M20 PF01546.23 EIE75958.1 - 1.7e-09 37.5 0.1 3e-09 36.6 0.1 1.4 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 Rotamase PF00639.16 EIE75959.1 - 2.4e-24 85.8 0.0 3e-24 85.5 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 EIE75959.1 - 2.4e-18 66.4 0.0 2.8e-18 66.2 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 EIE75959.1 - 7.4e-07 28.9 3.4 7.4e-07 28.9 2.4 2.0 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.1 EIE75959.1 - 3.5e-05 24.4 0.0 4.7e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain HLH PF00010.21 EIE75960.1 - 4.7e-13 48.6 1.2 4.7e-13 48.6 0.8 2.1 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain CENP-F_leu_zip PF10473.4 EIE75960.1 - 0.013 15.3 4.4 0.013 15.3 3.1 1.9 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 zf-C2H2 PF00096.21 EIE75961.1 - 5.5e-14 51.5 11.4 3.8e-07 30.0 1.2 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIE75961.1 - 5.7e-11 41.9 10.2 2.7e-05 24.2 0.7 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EIE75961.1 - 1.5e-09 37.6 15.0 1.2e-07 31.6 2.1 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EIE75961.1 - 0.0012 18.9 5.5 0.13 12.3 0.2 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding Ogr_Delta PF04606.7 EIE75961.1 - 0.0091 15.6 0.5 0.39 10.4 0.0 2.5 2 0 0 2 2 2 1 Ogr/Delta-like zinc finger zf-BED PF02892.10 EIE75961.1 - 0.015 15.0 5.7 0.21 11.3 0.2 2.4 2 0 0 2 2 2 0 BED zinc finger zf-met PF12874.2 EIE75961.1 - 0.02 15.0 8.3 0.44 10.8 1.0 3.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EIE75961.1 - 0.095 12.8 4.4 0.67 10.1 3.1 2.0 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-TRAF PF02176.13 EIE75961.1 - 0.14 12.5 4.4 1.2 9.5 2.6 2.2 1 1 0 1 1 1 0 TRAF-type zinc finger zf-C2H2_6 PF13912.1 EIE75961.1 - 1.4 8.9 7.4 0.77 9.7 0.4 2.8 2 1 0 2 2 2 0 C2H2-type zinc finger Mit_ribos_Mrp51 PF11709.3 EIE75962.1 - 7.3e-05 22.1 1.2 0.00066 18.9 0.8 2.0 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit TMEM247 PF15444.1 EIE75962.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 247 DUF3759 PF12585.3 EIE75963.1 - 2.1e-13 49.9 8.5 5.3e-13 48.6 5.9 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) Ricin_B_lectin PF00652.17 EIE75963.1 - 6.8e-05 22.8 0.0 0.15 12.1 0.0 2.6 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 EIE75963.1 - 0.00036 20.8 0.1 0.66 10.3 0.1 2.7 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Phage_GPL PF05926.6 EIE75963.1 - 0.054 13.3 2.8 0.092 12.5 1.9 1.3 1 0 0 1 1 1 0 Phage head completion protein (GPL) ABC2_membrane_3 PF12698.2 EIE75964.1 - 0.028 13.4 0.2 0.052 12.5 0.1 1.4 1 1 0 1 1 1 0 ABC-2 family transporter protein Mod_r PF07200.8 EIE75964.1 - 2 8.3 12.7 1.4 8.7 4.6 2.5 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF755 PF05501.6 EIE75964.1 - 2.2 8.3 8.5 0.17 11.9 1.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF755) OmpH PF03938.9 EIE75964.1 - 2.3 8.1 17.4 5.8 6.8 1.5 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF3713 PF12506.3 EIE75964.1 - 7.1 6.7 10.1 0.67 10.0 0.7 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3713) Fzo_mitofusin PF04799.8 EIE75964.1 - 7.5 5.9 12.7 2.1 7.7 0.7 2.7 2 1 0 2 2 2 0 fzo-like conserved region Syntaxin_2 PF14523.1 EIE75964.1 - 8.3 6.4 13.9 0.39 10.7 3.6 2.7 2 1 1 3 3 3 0 Syntaxin-like protein AIG1 PF04548.11 EIE75965.1 - 0.00012 21.2 0.1 0.00022 20.4 0.0 1.4 2 0 0 2 2 2 1 AIG1 family AAA-ATPase_like PF09820.4 EIE75965.1 - 0.013 14.7 0.0 0.026 13.6 0.0 1.5 2 0 0 2 2 2 0 Predicted AAA-ATPase PAP2 PF01569.16 EIE75966.1 - 5.2e-20 71.4 4.7 5.2e-20 71.4 3.3 2.4 2 2 0 2 2 2 1 PAP2 superfamily ECF-ribofla_trS PF07155.7 EIE75966.1 - 0.027 14.2 0.3 0.027 14.2 0.2 2.5 2 1 0 2 2 2 0 ECF-type riboflavin transporter, S component PSP1 PF04468.7 EIE75967.1 - 2.7e-33 113.8 3.6 4.9e-33 112.9 2.5 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Ribosomal_L3 PF00297.17 EIE75968.1 - 3.4e-120 400.3 10.0 4.1e-120 400.0 6.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 FadA PF09403.5 EIE75968.1 - 1.8 8.6 6.2 1.3 9.0 2.2 2.1 1 1 1 2 2 2 0 Adhesion protein FadA V-ATPase_G PF03179.10 EIE75969.1 - 1.5e-16 60.5 9.0 1.7e-16 60.4 6.2 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit Rhabdo_ncap PF00945.13 EIE75969.1 - 0.16 10.5 3.3 0.18 10.3 2.3 1.0 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Cob_adeno_trans PF01923.13 EIE75970.1 - 0.022 14.5 1.7 0.044 13.5 0.8 1.8 1 1 0 1 1 1 0 Cobalamin adenosyltransferase DUF4140 PF13600.1 EIE75970.1 - 4.3 7.8 11.0 21 5.6 0.4 3.5 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Matrilin_ccoil PF10393.4 EIE75970.1 - 6.4 6.2 6.7 1.8 8.0 0.5 2.4 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin DDE_3 PF13358.1 EIE75971.1 - 2.6e-19 69.4 0.2 3.3e-19 69.0 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE75972.1 - 3.1e-09 36.7 0.2 9.5e-09 35.2 0.0 1.9 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.1 EIE75972.1 - 3.7e-07 29.5 0.0 1.5e-05 24.4 0.0 2.6 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.1 EIE75972.1 - 1.4e-05 24.9 0.0 0.0004 20.3 0.0 2.5 2 1 0 2 2 2 1 Helix-turn-helix domain PAX PF00292.13 EIE75972.1 - 4.2e-05 23.2 0.0 0.0001 22.0 0.0 1.7 1 1 1 2 2 2 1 'Paired box' domain HTH_Tnp_ISL3 PF13542.1 EIE75972.1 - 0.00015 20.8 0.0 0.0041 16.2 0.0 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_11 PF08279.7 EIE75972.1 - 0.00057 19.4 0.2 0.011 15.4 0.0 2.3 2 0 0 2 2 2 1 HTH domain HTH_29 PF13551.1 EIE75972.1 - 0.0018 18.3 0.0 0.012 15.7 0.0 2.1 1 1 0 1 1 1 1 Winged helix-turn helix Trp_repressor PF01371.14 EIE75972.1 - 0.004 17.0 0.0 0.0074 16.1 0.0 1.4 1 0 0 1 1 1 1 Trp repressor protein LacI PF00356.16 EIE75972.1 - 0.013 15.0 0.0 7.8 6.2 0.0 2.6 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family GerE PF00196.14 EIE75972.1 - 0.017 14.4 0.2 0.1 11.9 0.1 2.0 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family CENP-B_N PF04218.8 EIE75972.1 - 0.022 14.1 0.1 0.23 10.9 0.1 2.2 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain HTH_7 PF02796.10 EIE75972.1 - 0.024 14.5 0.0 0.33 10.8 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_26 PF13443.1 EIE75972.1 - 0.037 14.2 0.0 0.56 10.4 0.0 2.3 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain DDE_3 PF13358.1 EIE75973.1 - 6.6e-09 35.6 2.4 1e-08 35.0 1.7 1.4 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE75973.1 - 0.00011 22.1 1.5 0.00029 20.8 1.0 1.6 1 0 0 1 1 1 1 Transposase NUDIX_4 PF14815.1 EIE75973.1 - 0.042 13.2 0.2 0.074 12.4 0.2 1.5 1 0 0 1 1 1 0 NUDIX domain DDE_3 PF13358.1 EIE75974.1 - 5.6e-15 55.3 0.2 7.2e-15 55.0 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EIE75975.1 - 1.4e-16 60.5 0.1 2.5e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE75975.1 - 5.1e-14 52.0 0.4 1.4e-13 50.6 0.3 1.8 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.1 EIE75975.1 - 5.3e-05 23.3 0.4 0.0001 22.4 0.3 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EIE75975.1 - 0.00031 20.2 0.2 0.0033 17.0 0.0 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_7 PF02796.10 EIE75975.1 - 0.0006 19.6 0.2 0.081 12.7 0.0 2.7 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase rve PF00665.21 EIE75975.1 - 0.0088 16.1 0.0 0.023 14.7 0.0 1.9 1 1 0 1 1 1 1 Integrase core domain Leader_Erm PF08253.6 EIE75976.1 - 0.33 10.4 0.3 0.33 10.4 0.2 2.1 2 0 0 2 2 2 0 Erm Leader peptide DDE_3 PF13358.1 EIE75977.1 - 3.8e-20 72.1 0.0 7.8e-20 71.1 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE75977.1 - 1.1e-15 57.4 1.7 2.8e-15 56.1 0.3 2.3 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 EIE75977.1 - 6e-06 26.3 1.5 8.6e-06 25.8 0.2 1.9 3 0 0 3 3 1 1 Winged helix-turn helix HTH_38 PF13936.1 EIE75977.1 - 1.2e-05 24.7 0.1 3.3e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.1 EIE75977.1 - 6.9e-05 22.3 0.1 0.0028 17.2 0.0 2.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.1 EIE75977.1 - 0.00012 22.7 2.9 0.02 15.6 0.1 3.6 4 0 0 4 4 3 1 Homeodomain-like domain Sigma70_r4_2 PF08281.7 EIE75977.1 - 0.00054 19.3 0.6 0.024 14.0 0.0 3.2 4 0 0 4 4 4 1 Sigma-70, region 4 HTH_28 PF13518.1 EIE75977.1 - 0.0012 18.7 0.0 0.0056 16.6 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_21 PF13276.1 EIE75977.1 - 0.0014 18.5 0.1 0.13 12.2 0.0 2.8 3 0 0 3 3 3 1 HTH-like domain HTH_7 PF02796.10 EIE75977.1 - 0.0022 17.7 1.1 0.1 12.4 0.0 2.8 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase rve PF00665.21 EIE75977.1 - 0.015 15.3 0.0 0.047 13.7 0.0 2.0 2 0 0 2 2 2 0 Integrase core domain HTH_Tnp_4 PF13613.1 EIE75977.1 - 0.023 14.2 0.1 0.057 12.9 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease LacI PF00356.16 EIE75977.1 - 0.027 14.0 2.3 2.8 7.6 0.2 2.7 3 0 0 3 3 3 0 Bacterial regulatory proteins, lacI family CPSase_L_D3 PF02787.14 EIE75977.1 - 0.054 13.2 0.0 0.14 11.8 0.0 1.7 2 0 0 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain HTH_36 PF13730.1 EIE75977.1 - 0.072 13.2 0.5 4.1 7.6 0.0 3.0 3 0 0 3 3 3 0 Helix-turn-helix domain Sigma70_r4 PF04545.11 EIE75977.1 - 0.1 11.9 0.2 0.79 9.0 0.0 2.6 4 0 0 4 4 4 0 Sigma-70, region 4 HTH_Tnp_ISL3 PF13542.1 EIE75977.1 - 0.16 11.1 2.8 8.4 5.6 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 HTH_17 PF12728.2 EIE75977.1 - 0.21 11.8 2.4 15 5.9 0.1 3.2 3 0 0 3 3 3 0 Helix-turn-helix domain Reo_sigmaC PF04582.7 EIE75978.1 - 0.015 14.4 0.2 0.02 14.0 0.2 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF3450 PF11932.3 EIE75978.1 - 0.017 14.3 0.6 0.025 13.8 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) bZIP_1 PF00170.16 EIE75978.1 - 0.028 14.3 1.7 0.074 13.0 1.2 1.8 1 0 0 1 1 1 0 bZIP transcription factor TMF_TATA_bd PF12325.3 EIE75978.1 - 0.05 13.3 1.0 0.082 12.6 0.7 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF4404 PF14357.1 EIE75978.1 - 0.053 13.9 0.5 5.1 7.5 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Med9 PF07544.8 EIE75978.1 - 0.056 13.1 0.5 0.2 11.3 0.3 1.9 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 CENP-F_leu_zip PF10473.4 EIE75978.1 - 0.065 13.0 2.2 0.1 12.4 1.5 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ADIP PF11559.3 EIE75978.1 - 0.07 13.0 0.9 0.12 12.2 0.6 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Exo_endo_phos_2 PF14529.1 EIE75979.1 - 1.3e-17 63.5 0.0 3e-17 62.3 0.0 1.7 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EIE75979.1 - 4.2e-06 26.8 0.0 1.1e-05 25.5 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RVT_1 PF00078.22 EIE75980.1 - 5.8e-27 94.4 0.0 1.1e-26 93.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PhoH PF02562.11 EIE75983.1 - 0.11 11.7 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein ACR_tran PF00873.14 EIE75983.1 - 0.12 9.7 0.1 0.15 9.4 0.0 1.0 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family HTH_Tnp_Tc3_2 PF01498.13 EIE75984.1 - 6.1e-14 51.8 0.3 1.6e-13 50.4 0.2 1.8 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.1 EIE75984.1 - 3.4e-05 23.9 0.5 6.4e-05 23.0 0.4 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EIE75984.1 - 0.00023 20.7 0.3 0.0032 17.0 0.0 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_7 PF02796.10 EIE75984.1 - 0.0015 18.3 0.4 0.092 12.6 0.1 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase DDE_3 PF13358.1 EIE75984.1 - 0.026 14.2 0.0 0.045 13.5 0.0 1.4 1 0 0 1 1 1 0 DDE superfamily endonuclease DDE_3 PF13358.1 EIE75985.1 - 3.7e-17 62.4 0.4 3.7e-17 62.4 0.3 1.4 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_3 PF13358.1 EIE75986.1 - 1.1e-14 54.4 0.0 3.6e-14 52.7 0.0 1.8 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE75986.1 - 8e-09 35.4 2.7 1.4e-08 34.6 0.2 2.5 2 1 1 3 3 3 1 Transposase HTH_23 PF13384.1 EIE75986.1 - 0.00032 20.2 0.0 0.00068 19.1 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_7 PF02796.10 EIE75986.1 - 0.0037 17.0 0.1 0.0099 15.7 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase NUDIX_4 PF14815.1 EIE75986.1 - 0.019 14.4 0.2 0.033 13.6 0.1 1.4 1 0 0 1 1 1 0 NUDIX domain DUF972 PF06156.8 EIE75988.1 - 6.2e-05 23.2 1.5 0.00011 22.5 1.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF972) TSC22 PF01166.13 EIE75988.1 - 8.2e-05 22.4 1.2 0.00018 21.3 0.8 1.5 1 0 0 1 1 1 1 TSC-22/dip/bun family DUF904 PF06005.7 EIE75988.1 - 0.0098 16.1 1.8 0.017 15.4 1.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF904) DUF947 PF06102.7 EIE75988.1 - 0.041 13.7 0.2 0.067 13.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF947) Syntaxin PF00804.20 EIE75988.1 - 0.058 13.5 0.8 0.11 12.6 0.5 1.5 1 0 0 1 1 1 0 Syntaxin DivIC PF04977.10 EIE75988.1 - 0.17 11.3 1.0 0.33 10.4 0.7 1.4 1 0 0 1 1 1 0 Septum formation initiator DUF4200 PF13863.1 EIE75988.1 - 0.56 10.1 4.7 1 9.3 3.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Transposase_21 PF02992.9 EIE75989.1 - 5.3e-22 78.0 0.0 7.8e-22 77.4 0.0 1.1 1 0 0 1 1 1 1 Transposase family tnp2 DDE_3 PF13358.1 EIE75990.1 - 4.1e-30 104.4 0.0 7.5e-30 103.6 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 EIE75990.1 - 5.7e-06 26.4 0.0 1.4e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.1 EIE75990.1 - 1.5e-05 24.8 0.9 3.4e-05 23.7 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_psq PF05225.11 EIE75990.1 - 1.6e-05 24.3 0.0 3.6e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_32 PF13565.1 EIE75990.1 - 5.1e-05 23.9 0.0 0.00027 21.6 0.0 2.3 3 0 0 3 3 1 1 Homeodomain-like domain HTH_23 PF13384.1 EIE75990.1 - 0.00025 20.5 0.0 0.00069 19.1 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_7 PF02796.10 EIE75990.1 - 0.0034 17.2 0.0 0.089 12.6 0.0 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase DDE_1 PF03184.14 EIE75990.1 - 0.0038 16.3 1.8 0.014 14.5 0.1 2.4 2 1 0 2 2 2 1 DDE superfamily endonuclease DUF1804 PF08822.6 EIE75990.1 - 0.0049 16.6 0.1 0.012 15.3 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1804) HTH_1 PF00126.22 EIE75990.1 - 0.0064 16.2 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family CENP-B_N PF04218.8 EIE75990.1 - 0.032 13.6 0.0 0.11 11.9 0.0 2.0 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_38 PF13936.1 EIE75990.1 - 0.045 13.3 0.0 0.35 10.4 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain rve PF00665.21 EIE75990.1 - 0.047 13.8 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain Sigma70_r4_2 PF08281.7 EIE75990.1 - 0.049 13.1 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 DUF2361 PF10153.4 EIE75990.1 - 0.061 13.5 3.9 0.11 12.7 0.6 2.5 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2361) TrmB PF01978.14 EIE75990.1 - 0.11 12.2 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB OLF PF02191.11 EIE75991.1 - 0.034 13.4 1.0 0.035 13.3 0.7 1.0 1 0 0 1 1 1 0 Olfactomedin-like domain DUF3958 PF13125.1 EIE75991.1 - 0.65 9.9 6.6 0.25 11.2 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3958) DUF2058 PF09831.4 EIE75991.1 - 1.2 8.9 9.7 1.5 8.6 6.7 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) rve PF00665.21 EIE75992.1 - 1.1e-21 77.1 0.0 1.9e-21 76.3 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 EIE75992.1 - 0.0031 16.9 0.0 0.0079 15.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.1 EIE75992.1 - 0.015 15.3 0.0 0.029 14.3 0.0 1.5 1 0 0 1 1 1 0 DDE domain rve PF00665.21 EIE75993.1 - 8.7e-18 64.5 0.0 3.7e-17 62.5 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 EIE75993.1 - 4e-14 52.5 0.9 1e-13 51.1 0.6 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE75993.1 - 1.4e-06 27.8 1.3 5.6e-06 25.9 0.7 2.2 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.1 EIE75993.1 - 4.7e-05 23.7 0.1 0.00046 20.6 0.0 2.4 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.15 EIE75993.1 - 0.00057 19.7 0.1 0.0021 17.9 0.0 2.0 1 0 0 1 1 1 1 Retroviral aspartyl protease Tudor-knot PF11717.3 EIE75993.1 - 0.019 14.6 0.7 0.054 13.2 0.5 1.8 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain YcgR_2 PF12945.2 EIE75993.1 - 0.028 14.2 0.0 0.42 10.5 0.0 2.5 2 0 0 2 2 2 0 Flagellar protein YcgR gag-asp_proteas PF13975.1 EIE75993.1 - 0.07 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVT_1 PF00078.22 EIE75994.1 - 7.7e-22 77.6 1.3 1.7e-21 76.5 0.4 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 EIE75994.1 - 3.1e-07 30.8 0.0 5.9e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EIE75994.1 - 1.5e-06 27.9 0.0 3.4e-06 26.7 0.0 1.6 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 EIE75994.1 - 1.8e-06 27.7 0.0 4.9e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.6 EIE75994.1 - 0.00039 20.3 0.0 0.00082 19.3 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Peptidase_A3 PF02160.10 EIE75994.1 - 0.014 15.0 3.9 0.019 14.5 1.0 2.2 2 0 0 2 2 2 0 Cauliflower mosaic virus peptidase (A3) Retrotrans_gag PF03732.12 EIE75995.1 - 1.9e-18 66.3 0.4 4.2e-18 65.2 0.3 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein DUF1649 PF07855.7 EIE75995.1 - 0.086 12.5 0.1 0.14 11.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1649) zf-CCHC PF00098.18 EIE75995.1 - 0.15 12.0 3.2 0.29 11.1 2.2 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.1 EIE75995.1 - 0.17 11.4 2.6 0.38 10.2 1.8 1.6 1 0 0 1 1 1 0 Zinc knuckle PG_binding_4 PF12229.3 EIE75995.1 - 0.31 11.2 2.6 0.52 10.5 0.2 2.5 3 1 0 3 3 3 0 Putative peptidoglycan binding domain DDE_3 PF13358.1 EIE75996.1 - 7.6e-14 51.6 0.1 1.1e-13 51.2 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE75996.1 - 0.0069 16.4 0.0 0.026 14.6 0.0 1.7 1 1 1 2 2 2 1 Integrase core domain Chromo PF00385.19 EIE75997.1 - 8.2e-12 44.6 0.6 1.6e-11 43.6 0.4 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain KxDL PF10241.4 EIE75997.1 - 0.076 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein rve PF00665.21 EIE75998.1 - 3.8e-14 52.8 0.0 1.1e-13 51.3 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain HTH_Tnp_Tc3_2 PF01498.13 EIE75999.1 - 8.6e-20 70.5 1.8 2.8e-19 68.9 0.8 2.0 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 EIE75999.1 - 2.1e-08 34.3 0.6 4.1e-08 33.3 0.4 1.4 1 1 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EIE75999.1 - 6.4e-05 22.4 1.7 0.003 17.1 0.0 3.1 3 1 0 3 3 3 1 Homeodomain-like domain HTH_32 PF13565.1 EIE75999.1 - 0.00013 22.7 2.3 0.00041 21.0 0.4 2.4 2 1 1 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.1 EIE75999.1 - 0.0067 16.4 0.1 0.028 14.4 0.0 2.1 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_12 PF08461.5 EIE75999.1 - 0.019 14.6 1.1 0.046 13.4 0.2 2.0 1 1 1 2 2 2 0 Ribonuclease R winged-helix domain HTH_21 PF13276.1 EIE75999.1 - 0.03 14.3 0.2 0.54 10.2 0.0 2.6 2 1 1 3 3 3 0 HTH-like domain HTH_40 PF14493.1 EIE75999.1 - 0.035 14.3 0.1 0.11 12.7 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_17 PF12728.2 EIE75999.1 - 0.045 13.9 0.8 0.21 11.8 0.1 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain Sigma70_r4_2 PF08281.7 EIE75999.1 - 0.17 11.3 0.6 19 4.8 0.1 2.4 2 0 0 2 2 2 0 Sigma-70, region 4 RNase_H PF00075.19 EIE76000.1 - 0.0071 16.6 0.0 0.014 15.6 0.0 1.5 1 0 0 1 1 1 1 RNase H Retrotrans_gag PF03732.12 EIE76001.1 - 8.2e-06 25.8 0.0 2.5e-05 24.2 0.0 1.9 1 0 0 1 1 1 1 Retrotransposon gag protein RVT_1 PF00078.22 EIE76001.1 - 6.9e-05 22.3 0.1 0.00014 21.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 EIE76001.1 - 0.0019 18.6 0.0 0.0053 17.2 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EIE76001.1 - 0.024 14.4 0.0 0.049 13.4 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Coatomer_WDAD PF04053.9 EIE76003.1 - 3.1e-135 451.4 0.5 5.2e-135 450.6 0.3 1.3 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.6 EIE76003.1 - 1.2e-75 254.6 0.1 1.5e-75 254.3 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 EIE76003.1 - 6.8e-55 181.1 11.9 9.8e-11 41.1 0.1 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 EIE76003.1 - 0.0014 16.8 6.3 1.4 7.0 0.0 4.0 1 1 2 4 4 4 3 Nucleoporin Nup120/160 CsgG PF03783.9 EIE76003.1 - 0.036 13.1 0.1 0.069 12.2 0.0 1.4 1 0 0 1 1 1 0 Curli production assembly/transport component CsgG HSP70 PF00012.15 EIE76004.1 - 6e-258 856.7 11.2 2.2e-134 448.6 0.6 2.0 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 EIE76004.1 - 1.9e-12 46.4 0.0 2.4e-10 39.5 0.0 3.0 2 1 0 2 2 2 1 MreB/Mbl protein Hydantoinase_A PF01968.13 EIE76004.1 - 0.0043 16.2 0.5 0.027 13.5 0.0 2.3 2 1 1 3 3 3 1 Hydantoinase/oxoprolinase FGGY_C PF02782.11 EIE76004.1 - 0.0056 16.3 0.0 0.015 14.8 0.0 1.7 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Prefoldin_2 PF01920.15 EIE76004.1 - 0.027 14.2 4.6 0.084 12.6 3.2 1.8 1 1 0 1 1 1 0 Prefoldin subunit StbA PF06406.6 EIE76004.1 - 0.031 13.2 0.0 0.059 12.2 0.0 1.5 1 0 0 1 1 1 0 StbA protein Glyco_hydro_20 PF00728.17 EIE76005.1 - 2.4e-21 76.2 0.0 4.6e-21 75.3 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain PolyA_pol PF01743.15 EIE76006.1 - 1.9e-15 57.1 0.0 3.7e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 EIE76006.1 - 1.5e-07 30.9 0.2 4.7e-07 29.2 0.1 1.9 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A WHIM1 PF15612.1 EIE76007.1 - 0.0099 15.7 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Kin17_mid PF10357.4 EIE76007.1 - 0.21 11.2 3.1 1.4 8.5 0.7 2.5 2 0 0 2 2 2 0 Domain of Kin17 curved DNA-binding protein Sel1 PF08238.7 EIE76008.1 - 2.7e-140 453.7 64.3 1.6e-12 47.6 0.0 15.4 16 0 0 16 16 16 15 Sel1 repeat TPR_6 PF13174.1 EIE76008.1 - 1.7e-07 31.2 9.5 16 6.2 0.0 9.1 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_17 PF13431.1 EIE76008.1 - 0.026 14.7 15.6 22 5.5 0.1 9.6 10 1 1 11 11 11 0 Tetratricopeptide repeat TPR_11 PF13414.1 EIE76008.1 - 0.31 10.7 43.5 0.23 11.1 0.7 9.5 3 2 6 10 10 10 0 TPR repeat Ribosomal_S24e PF01282.14 EIE76009.1 - 1.5e-35 120.8 0.3 2.4e-35 120.1 0.0 1.4 1 1 1 2 2 2 1 Ribosomal protein S24e Ribosomal_S2 PF00318.15 EIE76009.1 - 0.13 11.4 0.5 0.16 11.1 0.3 1.1 1 0 0 1 1 1 0 Ribosomal protein S2 DPPIV_N PF00930.16 EIE76010.1 - 5.3e-101 337.7 8.9 6.7e-101 337.3 6.2 1.1 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 EIE76010.1 - 5.6e-27 94.3 2.3 1e-26 93.5 1.6 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EIE76010.1 - 1.9e-05 24.4 0.1 3.8e-05 23.4 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIE76010.1 - 0.00055 19.8 0.2 0.0011 18.9 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EIE76010.1 - 0.0026 17.2 1.0 0.0052 16.2 0.7 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) COPIIcoated_ERV PF07970.7 EIE76011.1 - 1.2e-66 224.4 3.3 1.9e-66 223.8 2.3 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EIE76011.1 - 7.5e-31 105.9 0.4 1.8e-30 104.7 0.0 1.8 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) zf-RVT PF13966.1 EIE76012.1 - 1.3e-06 28.6 2.1 2.8e-06 27.5 1.5 1.6 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Prok-TraM PF09228.5 EIE76013.1 - 0.017 15.2 2.9 0.023 14.8 2.0 1.2 1 0 0 1 1 1 0 Prokaryotic Transcriptional repressor TraM Toprim PF01751.17 EIE76013.1 - 0.048 13.6 3.8 0.08 12.9 2.6 1.4 1 1 0 1 1 1 0 Toprim domain Peptidase_S49_N PF08496.5 EIE76013.1 - 0.05 13.4 10.7 0.059 13.1 7.4 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal IgaA PF07095.6 EIE76013.1 - 0.092 10.4 1.1 0.094 10.4 0.8 1.0 1 0 0 1 1 1 0 Intracellular growth attenuator protein IgaA Selenoprotein_S PF06936.6 EIE76013.1 - 0.13 11.7 7.1 0.15 11.5 4.9 1.1 1 0 0 1 1 1 0 Selenoprotein S (SelS) UPF0560 PF10577.4 EIE76013.1 - 0.21 9.7 6.8 0.25 9.5 4.7 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 FLO_LFY PF01698.11 EIE76013.1 - 0.23 10.2 10.5 0.26 10.0 7.3 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein RNase_H2-Ydr279 PF09468.5 EIE76013.1 - 0.46 9.6 9.9 0.54 9.4 6.8 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Glucan_synthase PF02364.10 EIE76013.1 - 0.54 8.0 6.4 0.6 7.9 4.4 1.1 1 0 0 1 1 1 0 1,3-beta-glucan synthase component IncA PF04156.9 EIE76013.1 - 1.1 8.8 7.2 1.2 8.6 5.0 1.1 1 0 0 1 1 1 0 IncA protein Ycf1 PF05758.7 EIE76013.1 - 1.2 6.7 10.9 1.2 6.7 7.6 1.0 1 0 0 1 1 1 0 Ycf1 GAGA_bind PF06217.7 EIE76013.1 - 2.1 8.2 9.0 2.2 8.1 6.3 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family CDC45 PF02724.9 EIE76013.1 - 2.4 6.0 9.4 2.4 6.0 6.5 1.1 1 0 0 1 1 1 0 CDC45-like protein BTV_NS2 PF04514.7 EIE76013.1 - 6.2 5.5 15.3 6.9 5.4 10.6 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 GCD14 PF08704.5 EIE76013.1 - 7 6.0 6.4 7.8 5.9 4.4 1.1 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit S1 PF00575.18 EIE76013.1 - 7.4 6.7 9.9 14 5.9 0.5 2.2 1 1 1 2 2 2 0 S1 RNA binding domain Ion_trans PF00520.26 EIE76015.1 - 2.6e-07 30.1 4.7 2.6e-07 30.1 3.3 1.9 2 0 0 2 2 2 1 Ion transport protein PKD_channel PF08016.7 EIE76015.1 - 0.00028 19.4 3.6 0.00033 19.2 2.5 1.3 1 0 0 1 1 1 1 Polycystin cation channel DUF805 PF05656.9 EIE76015.1 - 5.2 6.9 9.4 5.7 6.7 5.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF805) DUF912 PF06024.7 EIE76016.1 - 0.00065 19.7 0.4 0.0025 17.8 0.3 2.0 1 1 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) Rifin_STEVOR PF02009.11 EIE76016.1 - 0.0082 15.8 0.5 0.016 14.9 0.1 1.6 2 0 0 2 2 2 1 Rifin/stevor family FAM60A PF15396.1 EIE76016.1 - 0.036 13.8 0.1 0.055 13.2 0.1 1.2 1 0 0 1 1 1 0 Protein Family FAM60A OppC_N PF12911.2 EIE76016.1 - 0.056 12.8 1.3 0.14 11.5 0.9 1.7 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C DUF3139 PF11337.3 EIE76016.1 - 0.066 13.5 0.6 0.16 12.3 0.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3139) DUF2839 PF10999.3 EIE76016.1 - 0.093 12.7 0.3 1 9.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2839) Arrestin_C PF02752.17 EIE76017.1 - 2.8e-21 76.0 0.2 1.2e-17 64.3 0.1 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EIE76017.1 - 1.1e-18 67.4 0.0 1.8e-17 63.5 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 EIE76017.1 - 1.8e-05 24.3 0.1 4.4e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 Arrestin_N terminal like Glycoprotein_G PF00802.14 EIE76018.1 - 0.027 13.6 1.7 0.15 11.1 0.2 1.9 1 1 1 2 2 2 0 Pneumovirus attachment glycoprotein G bZIP_1 PF00170.16 EIE76020.1 - 7.9e-08 32.1 10.1 1.3e-06 28.2 7.0 2.5 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EIE76020.1 - 0.12 12.2 12.0 0.51 10.1 8.3 2.1 1 1 0 1 1 1 0 Basic region leucine zipper RVT_N PF13655.1 EIE76020.1 - 2.1 8.4 9.3 0.82 9.7 1.6 2.9 3 0 0 3 3 3 0 N-terminal domain of reverse transcriptase Peptidase_S64 PF08192.6 EIE76020.1 - 2.1 6.5 9.4 3.1 6.0 6.5 1.2 1 0 0 1 1 1 0 Peptidase family S64 Pho88 PF10032.4 EIE76021.1 - 7.2e-38 129.7 0.0 8.3e-38 129.5 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) WD40 PF00400.27 EIE76022.1 - 7.1e-53 174.6 15.9 1.1e-10 40.9 0.0 6.7 7 0 0 7 7 7 6 WD domain, G-beta repeat Striatin PF08232.7 EIE76022.1 - 8.6e-40 136.1 10.5 8.6e-40 136.1 7.3 2.2 2 0 0 2 2 2 1 Striatin family Nucleoporin_N PF08801.6 EIE76022.1 - 1.6e-10 40.3 3.9 0.0055 15.5 0.0 3.8 1 1 2 3 3 3 3 Nup133 N terminal like Nup160 PF11715.3 EIE76022.1 - 0.00026 19.3 5.9 0.017 13.2 0.2 4.1 1 1 1 4 4 4 2 Nucleoporin Nup120/160 DUF3236 PF11576.3 EIE76022.1 - 0.14 11.5 0.8 0.54 9.6 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3236) DNA_binding_1 PF01035.15 EIE76023.1 - 8.1e-19 67.1 0.0 1.1e-18 66.7 0.0 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Orthopox_F7 PF05813.7 EIE76023.1 - 0.16 11.8 0.8 0.33 10.8 0.5 1.5 1 0 0 1 1 1 0 Orthopoxvirus F7 protein Spt4 PF06093.8 EIE76024.1 - 6e-17 61.2 0.0 7e-17 61.0 0.0 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger zf-C2H2 PF00096.21 EIE76025.1 - 1e-09 38.1 41.5 0.00042 20.4 2.7 5.5 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIE76025.1 - 2.2e-09 37.1 22.5 3.4e-07 30.2 1.6 6.1 7 0 0 7 7 7 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 EIE76025.1 - 2e-06 27.6 60.5 0.00027 21.0 2.5 5.6 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EIE76025.1 - 7.5e-05 22.4 12.7 0.18 11.7 0.4 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger Mucin PF01456.12 EIE76025.1 - 0.0013 18.4 22.9 0.0063 16.2 4.3 2.2 2 0 0 2 2 2 2 Mucin-like glycoprotein zf-C2H2_jaz PF12171.3 EIE76025.1 - 0.27 11.4 18.0 0.17 12.0 0.8 4.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding SSP160 PF06933.6 EIE76025.1 - 0.32 8.9 18.6 0.71 7.7 2.5 2.0 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 Dicty_REP PF05086.7 EIE76025.1 - 0.51 8.0 19.6 0.08 10.6 6.8 2.1 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein TSA PF03249.8 EIE76025.1 - 5.6 5.3 5.5 8.2 4.8 3.8 1.1 1 0 0 1 1 1 0 Type specific antigen Mlo PF03094.10 EIE76025.1 - 6.6 4.7 7.5 11 3.9 5.2 1.3 1 0 0 1 1 1 0 Mlo family GSH_synth_ATP PF03917.12 EIE76026.1 - 1.9e-87 293.2 0.1 1.5e-86 290.2 0.1 1.9 1 1 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 EIE76026.1 - 4e-23 81.4 0.0 7.5e-23 80.6 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic glutathione synthase Sigma70_r4_2 PF08281.7 EIE76026.1 - 0.081 12.3 0.0 0.22 11.0 0.0 1.8 1 0 0 1 1 1 0 Sigma-70, region 4 EF-hand_1 PF00036.27 EIE76027.1 - 1.6e-40 133.2 11.1 5.3e-10 37.8 0.7 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EIE76027.1 - 1e-35 121.6 4.7 1.2e-19 70.1 0.3 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EIE76027.1 - 1.8e-31 107.4 11.1 1.8e-14 53.0 0.4 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 EIE76027.1 - 6.3e-30 100.3 4.8 7e-09 34.8 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EIE76027.1 - 9.8e-26 87.9 7.3 1.1e-06 27.7 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 EIE76027.1 - 2.3e-13 49.8 0.1 6.7e-06 25.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.4 EIE76027.1 - 9.9e-11 41.6 0.1 3.1e-05 23.9 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EIE76027.1 - 1.4e-08 34.3 1.9 0.00086 19.0 0.1 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand DUF1103 PF06513.6 EIE76027.1 - 5.1e-05 22.7 2.0 6.2e-05 22.5 1.4 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) EFhand_Ca_insen PF08726.5 EIE76027.1 - 0.00039 20.3 0.4 0.00039 20.3 0.3 2.0 3 0 0 3 3 3 1 Ca2+ insensitive EF hand EF-hand_like PF09279.6 EIE76027.1 - 0.00063 19.7 2.0 0.0031 17.5 0.2 2.5 2 1 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like TerB PF05099.8 EIE76027.1 - 0.00099 18.8 1.1 0.36 10.5 0.0 2.7 1 1 2 3 3 3 2 Tellurite resistance protein TerB UPF0154 PF03672.8 EIE76027.1 - 0.0027 17.2 1.7 0.063 12.9 0.0 3.1 3 1 1 4 4 4 1 Uncharacterised protein family (UPF0154) DUF2267 PF10025.4 EIE76027.1 - 0.019 15.0 0.0 0.066 13.2 0.0 1.9 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2267) Tenui_NCP PF04876.7 EIE76027.1 - 0.053 13.0 0.3 0.74 9.3 0.2 2.1 1 1 0 1 1 1 0 Tenuivirus major non-capsid protein RNA_pol_Rpb4 PF03874.11 EIE76027.1 - 0.055 13.4 3.6 1.3 9.0 0.2 2.7 3 0 0 3 3 3 0 RNA polymerase Rpb4 Toprim_2 PF13155.1 EIE76027.1 - 0.091 13.0 1.0 1.9 8.8 0.2 2.5 1 1 1 2 2 2 0 Toprim-like DUF853 PF05872.7 EIE76027.1 - 0.093 11.0 0.0 0.19 10.0 0.0 1.4 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF853) DUF3349 PF11829.3 EIE76027.1 - 0.097 13.1 0.4 4.6 7.7 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3349) DUF533 PF04391.7 EIE76027.1 - 0.24 10.7 1.4 6.5 6.0 0.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF533) DUF3018 PF11455.3 EIE76027.1 - 0.5 10.3 3.5 7.7 6.5 0.1 3.1 2 2 1 3 3 3 0 Protein of unknown function (DUF3018) ARD PF03079.9 EIE76028.1 - 4.7e-51 172.8 0.4 5.5e-51 172.6 0.3 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.6 EIE76028.1 - 1.2e-11 43.8 0.0 2e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 EIE76028.1 - 7.8e-09 35.3 0.0 1.2e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 EIE76028.1 - 0.003 17.0 0.0 0.0045 16.4 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.7 EIE76028.1 - 0.043 13.2 0.0 0.068 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Cupin_4 PF08007.7 EIE76028.1 - 0.051 12.8 0.0 0.085 12.0 0.0 1.3 1 0 0 1 1 1 0 Cupin superfamily protein GPI PF06560.6 EIE76028.1 - 0.054 12.5 0.0 0.07 12.1 0.0 1.3 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) DUF1498 PF07385.7 EIE76028.1 - 0.095 11.8 0.0 0.18 10.9 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1498) YqbF PF14553.1 EIE76028.1 - 0.095 12.3 0.1 0.23 11.1 0.1 1.6 1 0 0 1 1 1 0 YqbF, hypothetical protein domain Vps35 PF03635.12 EIE76029.1 - 0 1065.8 11.2 0 1065.5 7.8 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 SAPS PF04499.10 EIE76029.1 - 0.034 12.7 7.8 0.038 12.6 3.0 2.5 3 0 0 3 3 3 0 SIT4 phosphatase-associated protein GAGA_bind PF06217.7 EIE76029.1 - 1.1 9.1 8.8 1.9 8.3 6.1 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Presenilin PF01080.12 EIE76029.1 - 1.2 7.8 9.5 2 7.1 6.6 1.2 1 0 0 1 1 1 0 Presenilin Borrelia_P83 PF05262.6 EIE76029.1 - 3.4 5.8 22.6 5.2 5.2 15.6 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Asp-B-Hydro_N PF05279.6 EIE76029.1 - 4 7.2 35.3 7.5 6.3 24.5 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region CsbD PF05532.7 EIE76031.1 - 3.1e-17 61.9 13.8 1.4e-13 50.2 4.2 2.0 1 1 1 2 2 2 2 CsbD-like PhaP_Bmeg PF09602.5 EIE76031.1 - 0.0044 16.8 0.5 0.006 16.4 0.3 1.2 1 1 0 1 1 1 1 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) DUF3659 PF12396.3 EIE76031.1 - 0.51 10.0 3.6 9.5 5.9 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3659) Mito_carr PF00153.22 EIE76032.1 - 1.7e-66 219.9 5.5 3.3e-22 77.9 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 EIE76032.1 - 9.6e-15 54.4 1.8 9.9e-07 28.8 0.3 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EIE76032.1 - 1.2e-09 37.6 0.2 8.6e-06 25.2 0.0 2.9 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 EIE76032.1 - 6.4e-08 31.8 3.0 0.097 12.6 0.1 4.4 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.27 EIE76032.1 - 1.8e-07 29.9 2.9 0.00044 19.3 0.2 3.6 4 0 0 4 4 4 2 EF hand SPARC_Ca_bdg PF10591.4 EIE76032.1 - 0.0023 17.9 0.2 0.41 10.6 0.0 2.5 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_5 PF13202.1 EIE76032.1 - 0.058 12.7 0.1 0.62 9.5 0.1 2.3 2 0 0 2 2 2 0 EF hand DUF2482 PF10655.4 EIE76032.1 - 0.12 12.4 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 Hypothetical protein of unknown function (DUF2482) Phlebovirus_NSM PF07246.6 EIE76033.1 - 0.022 13.9 1.8 0.03 13.4 0.7 1.5 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M ATP-synt_ab PF00006.20 EIE76034.1 - 1.3e-69 233.9 0.0 2e-69 233.3 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EIE76034.1 - 6e-26 91.1 0.0 1.5e-25 89.8 0.0 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EIE76034.1 - 1.8e-20 72.8 0.6 1.8e-20 72.8 0.4 1.9 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EIE76034.1 - 2.6e-05 24.0 0.3 0.0001 22.1 0.2 2.0 1 1 1 2 2 2 1 HAS barrel domain Actin PF00022.14 EIE76035.1 - 5.5e-106 354.3 0.0 6.2e-106 354.1 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EIE76035.1 - 0.013 14.1 0.0 0.042 12.4 0.0 1.8 1 1 0 1 1 1 0 MreB/Mbl protein Methyltransf_5 PF01795.14 EIE76036.1 - 3.3e-59 200.6 0.0 1.3e-57 195.4 0.0 2.0 1 1 0 1 1 1 1 MraW methylase family Methyltransf_18 PF12847.2 EIE76036.1 - 0.006 17.1 0.0 0.019 15.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EIE76036.1 - 0.015 15.3 0.1 0.03 14.3 0.1 1.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase 3Beta_HSD PF01073.14 EIE76037.1 - 0.036 12.7 0.0 0.062 11.9 0.0 1.4 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family tRNA-synt_1 PF00133.17 EIE76038.1 - 1.1e-213 710.5 0.0 5.9e-213 708.1 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EIE76038.1 - 2.3e-35 121.6 0.3 5.4e-35 120.4 0.2 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EIE76038.1 - 1.1e-17 63.8 1.5 9e-10 37.7 0.0 5.0 5 1 0 5 5 5 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 EIE76038.1 - 2.2e-09 36.8 9.4 3e-08 33.1 0.1 3.1 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1d PF00750.14 EIE76038.1 - 0.015 14.1 0.0 0.055 12.2 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetases class I (R) tRNA-synt_1e PF01406.14 EIE76038.1 - 1.2 8.2 4.7 1.7 7.6 0.0 2.9 4 0 0 4 4 4 0 tRNA synthetases class I (C) catalytic domain WD40 PF00400.27 EIE76039.1 - 1.4e-23 81.7 7.5 5.2e-06 26.1 0.1 8.4 9 0 0 9 9 9 5 WD domain, G-beta repeat DDE_3 PF13358.1 EIE76041.1 - 5.3e-12 45.7 0.4 7.9e-12 45.1 0.2 1.5 1 1 0 1 1 1 1 DDE superfamily endonuclease DUF1841 PF08897.6 EIE76041.1 - 0.032 14.0 0.1 0.075 12.8 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1841) Prp19 PF08606.6 EIE76041.1 - 0.092 12.4 0.1 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Prp19/Pso4-like UpxZ PF06603.6 EIE76041.1 - 0.092 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 UpxZ family of transcription anti-terminator antagonists DUF3958 PF13125.1 EIE76041.1 - 0.31 10.9 2.5 5.7 6.9 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3958) Drc1-Sld2 PF11719.3 EIE76043.1 - 0.0001 21.5 0.3 0.0001 21.5 0.2 3.3 3 1 0 3 3 3 2 DNA replication and checkpoint protein CTP_transf_1 PF01148.15 EIE76044.1 - 2.5e-70 237.0 28.0 3.2e-70 236.7 19.4 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family ERGIC_N PF13850.1 EIE76044.1 - 0.69 9.9 4.9 1.2 9.1 0.2 3.3 3 0 0 3 3 3 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) SPT2 PF08243.6 EIE76045.1 - 2.5e-17 63.2 17.8 2.5e-17 63.2 12.4 4.4 3 1 1 4 4 4 1 SPT2 chromatin protein ABC_tran PF00005.22 EIE76046.1 - 1.6e-24 86.7 0.2 1e-23 84.1 0.0 2.2 2 1 0 2 2 1 1 ABC transporter SMC_N PF02463.14 EIE76046.1 - 2.6e-07 30.0 0.3 0.0017 17.6 0.0 2.5 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EIE76046.1 - 4e-07 30.3 0.1 8e-05 22.7 0.0 2.4 1 1 0 1 1 1 1 AAA domain Chromo PF00385.19 EIE76046.1 - 5.1e-06 26.0 0.2 1.4e-05 24.6 0.1 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_17 PF13207.1 EIE76046.1 - 2.2e-05 25.2 0.1 0.00012 22.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EIE76046.1 - 0.00028 20.0 0.0 0.0008 18.6 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF258 SbcCD_C PF13558.1 EIE76046.1 - 0.00039 20.2 0.0 0.0022 17.8 0.0 2.1 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.1 EIE76046.1 - 0.00089 18.8 0.2 0.41 10.1 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 EIE76046.1 - 0.0013 18.2 0.0 0.0029 17.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_28 PF13521.1 EIE76046.1 - 0.0014 18.6 0.4 0.0076 16.2 0.0 2.2 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EIE76046.1 - 0.002 18.0 0.8 0.0047 16.8 0.0 2.1 3 1 0 3 3 2 1 50S ribosome-binding GTPase Zeta_toxin PF06414.7 EIE76046.1 - 0.0033 16.5 0.3 0.91 8.5 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_16 PF13191.1 EIE76046.1 - 0.0042 17.0 0.0 0.011 15.7 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EIE76046.1 - 0.01 15.9 0.0 0.12 12.5 0.0 2.5 3 0 0 3 3 2 0 AAA domain Miro PF08477.8 EIE76046.1 - 0.01 16.2 0.0 0.03 14.8 0.0 1.8 1 1 0 1 1 1 0 Miro-like protein MobB PF03205.9 EIE76046.1 - 0.014 15.1 0.4 0.037 13.7 0.0 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ArgK PF03308.11 EIE76046.1 - 0.016 13.9 0.0 0.016 13.9 0.0 1.6 2 0 0 2 2 2 0 ArgK protein AAA_18 PF13238.1 EIE76046.1 - 0.021 15.1 2.0 0.023 14.9 0.1 2.1 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 EIE76046.1 - 0.029 13.8 0.0 0.15 11.5 0.0 2.2 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_10 PF12846.2 EIE76046.1 - 0.03 13.7 0.0 0.15 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA-like domain RNA_helicase PF00910.17 EIE76046.1 - 0.035 14.2 0.0 0.074 13.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.1 EIE76046.1 - 0.037 13.9 0.0 0.086 12.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain DUF87 PF01935.12 EIE76046.1 - 0.056 13.2 1.5 0.14 11.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF87 PEX-2N PF09263.5 EIE76046.1 - 0.081 13.2 0.0 0.24 11.7 0.0 1.7 1 1 0 1 1 1 0 Peroxisome biogenesis factor 1, N-terminal AAA PF00004.24 EIE76046.1 - 0.089 12.9 0.0 0.28 11.3 0.0 1.9 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.18 EIE76046.1 - 0.13 12.1 1.9 0.14 11.9 0.0 1.9 2 1 0 2 2 2 0 Dynamin family RabGAP-TBC PF00566.13 EIE76047.1 - 2.5e-48 164.3 0.0 4.7e-48 163.5 0.0 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_6 PF13405.1 EIE76047.1 - 0.00045 19.8 0.7 0.0092 15.7 0.1 2.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.27 EIE76047.1 - 0.016 14.4 3.0 0.02 14.1 0.5 2.4 2 0 0 2 2 2 0 EF hand EF-hand_7 PF13499.1 EIE76047.1 - 0.02 15.0 1.6 0.5 10.5 0.1 3.0 2 1 0 2 2 2 0 EF-hand domain pair RRM_6 PF14259.1 EIE76048.1 - 1.7e-09 37.5 0.0 2.7e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EIE76048.1 - 1.9e-07 30.5 0.0 2.8e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE76048.1 - 9.4e-06 25.3 0.0 1.4e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Corona_nucleoca PF00937.13 EIE76048.1 - 0.0046 15.9 0.2 0.007 15.3 0.1 1.3 1 0 0 1 1 1 1 Coronavirus nucleocapsid protein RRM_2 PF04059.7 EIE76048.1 - 0.12 12.4 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif 2 EF-hand_4 PF12763.2 EIE76049.1 - 4e-44 148.6 0.2 1.5e-17 63.2 0.0 4.0 4 0 0 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 EIE76049.1 - 2e-11 42.3 0.4 0.24 10.8 0.0 6.2 6 0 0 6 6 6 3 EF hand EF-hand_7 PF13499.1 EIE76049.1 - 2e-11 43.8 0.6 0.00044 20.3 0.1 4.2 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.1 EIE76049.1 - 6.7e-06 25.5 2.7 24 5.1 0.1 6.1 6 0 0 6 6 6 0 EF-hand domain EF-hand_8 PF13833.1 EIE76049.1 - 6.2e-05 22.5 0.0 0.48 10.0 0.0 4.0 4 0 0 4 4 4 2 EF-hand domain pair Cast PF10174.4 EIE76049.1 - 0.0005 18.2 24.0 0.0005 18.2 16.6 1.9 1 1 1 2 2 2 1 RIM-binding protein of the cytomatrix active zone Reo_sigmaC PF04582.7 EIE76049.1 - 0.036 13.2 9.9 0.0093 15.1 4.1 1.8 1 1 1 2 2 2 0 Reovirus sigma C capsid protein EF-hand_10 PF14788.1 EIE76049.1 - 0.057 13.0 0.6 5.4 6.7 0.0 3.6 3 0 0 3 3 3 0 EF hand TPR_MLP1_2 PF07926.7 EIE76049.1 - 0.17 11.6 29.8 0.15 11.7 5.7 2.6 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein IncA PF04156.9 EIE76049.1 - 0.51 9.9 33.4 0.044 13.3 15.1 2.4 1 1 1 2 2 2 0 IncA protein FlaC_arch PF05377.6 EIE76049.1 - 0.87 9.5 10.4 3.5 7.5 0.9 3.0 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) CENP-F_leu_zip PF10473.4 EIE76049.1 - 2 8.2 29.7 0.49 10.2 12.5 2.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tup_N PF08581.5 EIE76049.1 - 4.9 7.4 19.6 2.5 8.3 3.4 3.2 2 1 1 3 3 3 0 Tup N-terminal PCI_Csn8 PF10075.4 EIE76053.1 - 2e-25 89.2 0.2 2.9e-25 88.7 0.1 1.2 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 EIE76053.1 - 3.2e-22 79.0 0.4 4.2e-22 78.7 0.3 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI PF01399.22 EIE76053.1 - 0.019 15.2 0.1 0.078 13.3 0.0 2.0 2 0 0 2 2 2 0 PCI domain DUF1433 PF07252.6 EIE76053.1 - 0.53 10.5 2.9 1.5 9.0 0.0 2.6 3 1 0 3 3 3 0 Protein of unknown function (DUF1433) UPF0183 PF03676.9 EIE76054.1 - 2e-63 214.3 1.3 1.1e-37 129.6 1.1 3.2 1 1 2 3 3 3 3 Uncharacterised protein family (UPF0183) DUF676 PF05057.9 EIE76055.1 - 4.3e-09 35.9 0.0 5.1e-09 35.7 0.0 1.0 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Metalloenzyme PF01676.13 EIE76056.1 - 2.6e-11 43.3 0.1 4.1e-11 42.7 0.0 1.2 1 1 0 1 1 1 1 Metalloenzyme superfamily PhosphMutase PF10143.4 EIE76056.1 - 0.00039 20.1 0.0 0.00057 19.5 0.0 1.2 1 0 0 1 1 1 1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase RhoGEF PF00621.15 EIE76057.1 - 1.7e-15 57.3 8.3 3.5e-15 56.3 5.7 1.5 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.24 EIE76057.1 - 0.0014 18.7 0.0 0.006 16.7 0.0 2.1 1 0 0 1 1 1 1 PH domain PAN_4 PF14295.1 EIE76057.1 - 0.36 10.5 1.9 0.73 9.5 1.3 1.5 1 0 0 1 1 1 0 PAN domain DUF1772 PF08592.6 EIE76058.1 - 2.1e-12 46.9 0.3 4.2e-12 45.9 0.2 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) TMEM237 PF15383.1 EIE76058.1 - 0.012 14.7 0.3 2.6 7.0 0.0 2.1 2 0 0 2 2 2 0 Transmembrane protein 237 DUF1767 PF08585.7 EIE76059.1 - 3.7e-09 36.7 0.0 1.4e-08 34.8 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1767) Mob1_phocein PF03637.12 EIE76060.1 - 1.7e-05 24.5 0.0 2.3e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Mob1/phocein family MIT PF04212.13 EIE76061.1 - 0.031 14.1 0.0 0.051 13.4 0.0 1.4 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain GYF PF02213.11 EIE76062.1 - 1.5e-17 62.9 0.1 3.4e-17 61.7 0.1 1.7 1 0 0 1 1 1 1 GYF domain PAT1 PF09770.4 EIE76062.1 - 6.4 4.8 63.9 0.096 10.9 26.0 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Mo25 PF08569.6 EIE76063.1 - 6.4e-121 403.4 12.9 7.6e-121 403.2 9.0 1.0 1 0 0 1 1 1 1 Mo25-like RepA_N PF06970.6 EIE76063.1 - 0.13 12.0 2.8 0.23 11.2 0.6 2.4 2 0 0 2 2 2 0 Replication initiator protein A (RepA) N-terminus DUF544 PF04424.8 EIE76063.1 - 0.42 10.4 3.5 0.36 10.6 0.3 2.3 2 1 0 3 3 3 0 Protein of unknown function (DUF544) PhoU_div PF01865.11 EIE76064.1 - 0.047 12.8 0.4 0.16 11.1 0.3 1.7 1 1 0 1 1 1 0 Protein of unknown function DUF47 RasGEF PF00617.14 EIE76065.1 - 2e-45 154.8 1.9 3.2e-45 154.1 1.3 1.3 1 0 0 1 1 1 1 RasGEF domain RasGAP PF00616.14 EIE76067.1 - 8.6e-05 22.2 0.0 0.00015 21.4 0.0 1.4 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.25 EIE76067.1 - 0.068 13.0 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 C2 domain DUF321 PF03778.8 EIE76067.1 - 0.29 10.5 3.8 0.68 9.4 2.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF321) Cnd3 PF12719.2 EIE76069.1 - 2.5e-73 246.6 14.6 4e-72 242.7 8.0 2.9 3 1 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 EIE76069.1 - 2.3e-08 34.2 11.0 0.0077 16.4 0.5 5.4 5 1 1 6 6 6 4 HEAT repeats HEAT PF02985.17 EIE76069.1 - 2.4e-07 30.2 4.3 0.33 11.1 0.0 5.1 4 0 0 4 4 4 3 HEAT repeat MA3 PF02847.12 EIE76069.1 - 0.0046 16.6 4.5 0.026 14.2 0.3 3.3 3 0 0 3 3 3 1 MA3 domain HEAT_EZ PF13513.1 EIE76069.1 - 0.021 15.3 4.1 63 4.2 0.0 5.2 5 0 0 5 5 5 0 HEAT-like repeat PYRIN PF02758.11 EIE76069.1 - 0.021 14.4 0.7 0.14 11.8 0.5 2.6 1 0 0 1 1 1 0 PAAD/DAPIN/Pyrin domain DUF1744 PF08490.7 EIE76071.1 - 8.2e-114 380.2 0.3 1.3e-113 379.6 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 EIE76071.1 - 9.5e-65 218.5 2.9 9.5e-65 218.5 2.0 2.1 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 EIE76071.1 - 4.8e-18 65.1 0.0 1.7e-16 60.0 0.0 2.6 2 1 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 EIE76071.1 - 4.6e-09 36.1 0.5 1.5e-08 34.4 0.3 1.8 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 EIE76071.1 - 1.5e-05 24.8 0.3 0.00012 21.9 0.0 2.8 2 0 0 2 2 2 1 RNase_H superfamily Tetraspannin PF00335.15 EIE76072.1 - 6e-05 22.4 9.7 6e-05 22.4 6.7 2.7 1 1 1 2 2 2 1 Tetraspanin family Claudin_2 PF13903.1 EIE76072.1 - 0.25 11.0 14.7 0.24 11.0 5.6 2.8 2 1 1 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction Lig_chan PF00060.21 EIE76072.1 - 0.43 10.2 9.1 0.95 9.1 6.3 1.7 1 1 0 1 1 1 0 Ligand-gated ion channel DUF4064 PF13273.1 EIE76072.1 - 2.3 8.3 8.8 3.7 7.7 2.5 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF4064) Ribosomal_L7Ae PF01248.21 EIE76073.1 - 5.7e-27 93.0 0.0 6.6e-27 92.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family AFG1_ATPase PF03969.11 EIE76074.1 - 0.027 13.2 0.7 0.28 9.9 0.0 2.1 2 0 0 2 2 2 0 AFG1-like ATPase HECT PF00632.20 EIE76075.1 - 1.3e-80 270.9 0.1 2.7e-80 269.8 0.1 1.6 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SDA1 PF05285.7 EIE76075.1 - 1.3 8.1 56.9 0.24 10.6 2.6 3.2 3 0 0 3 3 3 0 SDA1 Daxx PF03344.10 EIE76075.1 - 1.7 6.9 58.6 1.3 7.3 10.7 3.1 3 0 0 3 3 3 0 Daxx Family UCH PF00443.24 EIE76077.1 - 5.5e-50 169.9 0.8 8e-49 166.1 0.6 2.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 EIE76077.1 - 2.3e-16 59.9 0.4 2.3e-16 59.9 0.3 2.6 3 0 0 3 3 3 1 DUSP domain UCH_1 PF13423.1 EIE76077.1 - 5.2e-13 49.0 1.3 5.2e-09 35.9 0.0 3.4 3 0 0 3 3 3 3 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.1 EIE76077.1 - 1.3e-08 34.4 3.5 9.5e-08 31.7 0.1 3.0 3 0 0 3 3 3 1 Ubiquitin-specific protease C-terminal DUF1675 PF07897.6 EIE76077.1 - 0.23 11.3 3.6 0.46 10.3 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Ribosomal_L14e PF01929.12 EIE76078.1 - 2.6e-24 85.3 3.8 3.8e-24 84.8 2.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 EIE76078.1 - 6.8e-05 22.4 1.0 0.00019 21.0 0.7 1.8 1 0 0 1 1 1 1 KOW motif Palm_thioest PF02089.10 EIE76079.1 - 8.9e-26 90.4 0.2 2.2e-24 85.8 0.2 2.0 1 1 0 1 1 1 1 Palmitoyl protein thioesterase Palm_thioest PF02089.10 EIE76080.1 - 3.1e-08 32.8 0.0 4.7e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF2986 PF11661.3 EIE76082.1 - 0.55 10.5 3.1 0.82 10.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2986) Pyr_redox_2 PF07992.9 EIE76083.1 - 2.2e-27 96.2 0.0 4e-26 92.1 0.0 3.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EIE76083.1 - 1.4e-14 54.2 0.0 1.6e-11 44.4 0.0 3.3 3 2 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EIE76083.1 - 7.1e-07 29.4 0.2 0.034 14.1 0.0 3.4 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DUF1111 PF06537.6 EIE76083.1 - 0.043 12.0 0.6 0.069 11.4 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1111) TPPII_N PF12583.3 EIE76083.1 - 0.069 13.2 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal NAD_binding_7 PF13241.1 EIE76083.1 - 0.081 13.1 0.2 8.4 6.7 0.0 2.9 2 2 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_9 PF13454.1 EIE76083.1 - 0.096 12.4 0.2 34 4.1 0.0 3.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding HI0933_like PF03486.9 EIE76083.1 - 0.098 11.1 2.8 0.16 10.3 0.0 2.4 2 1 1 3 3 3 0 HI0933-like protein Cyt-b5 PF00173.23 EIE76084.1 - 1.7e-16 59.7 0.0 4.4e-16 58.4 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.19 EIE76084.1 - 2.5e-15 56.6 24.8 4.9e-15 55.6 17.2 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Pox_P35 PF03213.9 EIE76084.1 - 0.074 12.0 0.2 0.12 11.3 0.1 1.2 1 0 0 1 1 1 0 Poxvirus P35 protein zf-CCHC PF00098.18 EIE76088.1 - 1.5e-06 27.8 10.1 0.0013 18.5 0.3 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 EIE76088.1 - 6.1e-05 22.6 3.2 0.014 15.0 0.0 2.6 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.1 EIE76088.1 - 0.025 14.2 0.6 0.025 14.2 0.4 2.1 2 0 0 2 2 2 0 Zinc knuckle RVT_1 PF00078.22 EIE76089.1 - 3.6e-23 82.0 0.0 6.3e-23 81.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.1 EIE76089.1 - 0.0019 18.4 2.5 0.0045 17.2 1.7 1.6 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase RVT_1 PF00078.22 EIE76090.1 - 1.6e-31 109.3 0.0 2.8e-31 108.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Antigen_Bd37 PF11641.3 EIE76091.1 - 0.13 11.5 0.3 0.24 10.6 0.2 1.4 1 0 0 1 1 1 0 Glycosylphosphatidylinositol-anchored merozoite surface protein DUF2296 PF10058.4 EIE76091.1 - 0.16 11.7 1.5 0.38 10.5 1.0 1.6 1 0 0 1 1 1 0 Predicted integral membrane metal-binding protein (DUF2296) TEX13 PF15186.1 EIE76091.1 - 0.38 10.3 3.8 0.12 11.9 0.4 1.7 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family IncA PF04156.9 EIE76091.1 - 0.45 10.0 4.3 1.2 8.7 3.0 1.8 1 1 0 1 1 1 0 IncA protein Ima1_N PF09779.4 EIE76091.1 - 0.54 10.7 5.7 11 6.5 3.9 2.9 1 1 0 1 1 1 0 Ima1 N-terminal domain ADK_lid PF05191.9 EIE76091.1 - 5.5 6.7 6.1 9.4 6.0 0.3 2.2 1 1 1 2 2 2 0 Adenylate kinase, active site lid PPV_E1_N PF00524.13 EIE76092.1 - 0.13 12.5 3.7 0.21 11.8 0.1 2.3 2 0 0 2 2 2 0 E1 Protein, N terminal domain RVT_1 PF00078.22 EIE76093.1 - 9.1e-33 113.4 0.0 2.7e-32 111.8 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Osmo_MPGsynth PF09488.5 EIE76093.1 - 0.0013 17.5 0.1 0.0023 16.6 0.1 1.3 1 0 0 1 1 1 1 Mannosyl-3-phosphoglycerate synthase (osmo_MPGsynth) TMF_TATA_bd PF12325.3 EIE76094.1 - 1.1e-05 25.0 2.8 1.7e-05 24.4 0.9 2.1 2 0 0 2 2 2 1 TATA element modulatory factor 1 TATA binding DivIVA PF05103.8 EIE76094.1 - 0.00014 21.8 4.6 0.00014 21.8 3.2 2.2 3 0 0 3 3 1 1 DivIVA protein DUF2296 PF10058.4 EIE76094.1 - 0.00037 20.1 0.7 0.00089 18.9 0.5 1.7 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) CENP-F_leu_zip PF10473.4 EIE76094.1 - 0.00039 20.2 3.1 0.00039 20.2 2.1 2.0 2 0 0 2 2 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Golgin_A5 PF09787.4 EIE76094.1 - 0.00055 18.5 7.0 0.00091 17.8 4.9 1.4 1 0 0 1 1 1 1 Golgin subfamily A member 5 FliJ PF02050.11 EIE76094.1 - 0.016 15.2 6.9 0.016 15.2 4.8 2.0 3 0 0 3 3 1 0 Flagellar FliJ protein DUF948 PF06103.6 EIE76094.1 - 0.02 14.7 1.5 0.038 13.8 1.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Zn_Tnp_IS1 PF03811.8 EIE76094.1 - 0.041 13.3 4.5 0.095 12.2 3.1 1.6 1 0 0 1 1 1 0 InsA N-terminal domain DivIC PF04977.10 EIE76094.1 - 0.046 13.2 2.0 0.14 11.7 1.4 1.8 1 0 0 1 1 1 0 Septum formation initiator zf-CCHC PF00098.18 EIE76094.1 - 0.067 13.1 0.3 0.067 13.1 0.2 1.8 2 0 0 2 2 1 0 Zinc knuckle CCDC144C PF14915.1 EIE76094.1 - 0.08 11.8 10.0 0.14 11.0 7.0 1.4 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region TBPIP PF07106.8 EIE76094.1 - 0.081 12.4 3.7 0.27 10.7 2.6 1.9 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TMF_DNA_bd PF12329.3 EIE76094.1 - 0.088 12.6 2.8 0.23 11.2 1.9 1.7 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding HR1 PF02185.11 EIE76094.1 - 0.096 12.4 4.9 0.14 11.8 1.9 2.4 2 0 0 2 2 2 0 Hr1 repeat Bap31 PF05529.7 EIE76094.1 - 0.11 11.9 2.7 0.27 10.6 1.9 1.6 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like GrpE PF01025.14 EIE76094.1 - 0.2 11.1 2.6 0.83 9.1 0.9 2.3 2 0 0 2 2 2 0 GrpE IncA PF04156.9 EIE76094.1 - 0.23 11.0 5.7 0.12 11.9 2.4 1.8 2 0 0 2 2 2 0 IncA protein Spc24 PF08286.6 EIE76094.1 - 0.35 10.5 4.8 0.087 12.5 0.7 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Zn_Tnp_IS1595 PF12760.2 EIE76094.1 - 0.65 9.8 4.6 1.5 8.6 3.2 1.6 1 0 0 1 1 1 0 Transposase zinc-ribbon domain V_ATPase_I PF01496.14 EIE76094.1 - 1.1 7.0 4.2 1.5 6.5 2.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Zn-ribbon_8 PF09723.5 EIE76094.1 - 1.2 9.1 5.7 16 5.5 0.0 2.8 2 1 0 2 2 2 0 Zinc ribbon domain FUSC PF04632.7 EIE76094.1 - 1.7 7.0 3.5 2.2 6.6 2.4 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4407 PF14362.1 EIE76094.1 - 3.6 6.4 8.4 5.7 5.7 5.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4140 PF13600.1 EIE76094.1 - 3.9 7.9 7.4 0.59 10.6 0.9 2.4 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) zf-ISL3 PF14690.1 EIE76094.1 - 5.2 7.1 7.4 1.8 8.6 2.6 2.3 2 1 1 3 3 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-CCCH PF00642.19 EIE76095.1 - 1.2e-20 72.6 17.4 3e-11 42.7 3.0 2.1 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EIE76095.1 - 0.0096 15.8 11.7 0.47 10.5 1.3 2.8 2 1 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type AFT PF08731.6 EIE76095.1 - 0.01 16.0 0.4 0.016 15.3 0.2 1.3 1 0 0 1 1 1 0 Transcription factor AFT oligo_HPY PF08352.7 EIE76095.1 - 0.044 14.1 3.6 4.9 7.5 0.2 2.3 2 0 0 2 2 2 0 Oligopeptide/dipeptide transporter, C-terminal region zf-CCHH PF10283.4 EIE76095.1 - 0.91 9.4 11.7 2.5 7.9 0.4 3.1 3 0 0 3 3 3 0 Zinc-finger (CX5CX6HX5H) motif PMR5N PF14416.1 EIE76095.1 - 1.3 9.1 6.2 4.2 7.4 0.4 2.3 1 1 1 2 2 2 0 PMR5 N terminal Domain Peptidase_M16_C PF05193.16 EIE76096.1 - 1.1e-34 119.7 0.0 2.2e-34 118.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EIE76096.1 - 2e-27 95.7 0.8 6.7e-27 94.0 0.5 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) GAS PF13851.1 EIE76096.1 - 0.0072 15.5 0.2 0.013 14.7 0.1 1.3 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Striatin PF08232.7 EIE76096.1 - 0.019 15.2 0.1 0.066 13.5 0.0 1.9 2 0 0 2 2 2 0 Striatin family Pkinase PF00069.20 EIE76097.1 - 3.9e-23 81.9 0.0 4.5e-23 81.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 EIE76097.1 - 0.0033 16.4 0.0 0.005 15.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EIE76097.1 - 0.013 15.2 0.1 0.073 12.7 0.0 2.1 2 2 0 3 3 3 0 Phosphotransferase enzyme family RIO1 PF01163.17 EIE76097.1 - 0.049 12.9 0.0 0.09 12.1 0.0 1.4 1 0 0 1 1 1 0 RIO1 family YrbL-PhoP_reg PF10707.4 EIE76097.1 - 0.066 12.5 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RNase_P_Rpp14 PF01900.14 EIE76100.1 - 1.9e-05 24.5 0.2 0.057 13.3 0.0 2.1 1 1 1 2 2 2 2 Rpp14/Pop5 family WD40 PF00400.27 EIE76103.1 - 1.5e-08 34.1 0.6 0.19 11.6 0.1 5.7 6 1 1 7 7 7 3 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EIE76103.1 - 0.012 14.4 0.1 0.025 13.3 0.1 1.8 1 1 0 1 1 1 0 Nup133 N terminal like zf-CCHC PF00098.18 EIE76104.1 - 0.00093 19.0 0.1 0.0017 18.2 0.1 1.4 1 0 0 1 1 1 1 Zinc knuckle DUF1660 PF07874.6 EIE76104.1 - 0.14 12.4 0.1 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 Prophage protein (DUF1660) DDE_3 PF13358.1 EIE76105.1 - 5.5e-29 100.8 0.0 9.9e-29 99.9 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_1 PF01527.15 EIE76105.1 - 4.5e-05 23.3 0.2 0.00011 22.1 0.1 1.6 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.1 EIE76105.1 - 0.00038 21.1 0.0 0.006 17.3 0.0 2.5 2 0 0 2 2 2 1 Homeodomain-like domain CP12 PF02672.10 EIE76105.1 - 0.0037 17.6 1.1 0.0086 16.5 0.8 1.6 1 0 0 1 1 1 1 CP12 domain HTH_28 PF13518.1 EIE76105.1 - 0.0092 15.9 0.0 0.026 14.5 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_psq PF05225.11 EIE76105.1 - 0.023 14.2 0.1 0.066 12.7 0.1 1.7 1 0 0 1 1 1 0 helix-turn-helix, Psq domain YniB PF14002.1 EIE76105.1 - 0.036 13.5 0.0 0.49 9.8 0.0 2.1 2 0 0 2 2 2 0 YniB-like protein PRESAN PF09687.5 EIE76105.1 - 0.042 13.8 2.3 0.81 9.7 0.6 2.7 2 1 0 2 2 2 0 Plasmodium RESA N-terminal HTH_29 PF13551.1 EIE76105.1 - 0.06 13.4 0.0 0.21 11.7 0.0 1.9 2 0 0 2 2 2 0 Winged helix-turn helix DDE_Tnp_ISAZ013 PF07592.6 EIE76105.1 - 0.085 11.5 0.1 1.3 7.7 0.0 2.3 2 1 1 3 3 3 0 Rhodopirellula transposase DDE domain DUF3486 PF11985.3 EIE76105.1 - 0.63 10.0 0.0 0.63 10.0 0.0 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3486) DUF792 PF05632.6 EIE76106.1 - 0.059 12.7 0.0 0.062 12.6 0.0 1.1 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF792) NAPRTase PF04095.11 EIE76108.1 - 1.2e-61 208.1 0.6 1.7e-61 207.5 0.4 1.3 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family DUF4163 PF13739.1 EIE76108.1 - 0.23 12.2 4.3 0.19 12.5 1.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4163) ENT PF03735.9 EIE76109.1 - 0.0013 18.4 2.5 0.0073 15.9 1.7 2.3 1 0 0 1 1 1 1 ENT domain Thiolase_N PF00108.18 EIE76110.1 - 5.2e-100 333.7 2.6 5.2e-100 333.7 1.8 1.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EIE76110.1 - 1.4e-39 134.2 4.1 3.3e-39 133.1 0.6 2.9 4 0 0 4 4 4 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EIE76110.1 - 8.2e-06 25.4 1.9 6.6e-05 22.5 0.3 2.6 1 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Methyltransf_23 PF13489.1 EIE76111.1 - 8.4e-08 32.0 0.0 1.2e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIE76111.1 - 2.5e-06 27.1 0.0 5.1e-06 26.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIE76111.1 - 4.8e-05 23.7 0.0 0.0001 22.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIE76111.1 - 0.00011 21.3 0.0 0.001 18.2 0.0 2.1 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EIE76111.1 - 0.00017 21.9 0.0 0.00037 20.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain AAA_14 PF13173.1 EIE76111.1 - 0.15 11.9 0.3 0.37 10.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain Phage_integrase PF00589.17 EIE76112.1 - 1.2e-07 31.5 0.1 1.5e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family Cellulase PF00150.13 EIE76115.1 - 2.1e-13 50.1 0.1 1e-12 47.9 0.0 2.2 2 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Ras PF00071.17 EIE76116.1 - 6.4e-61 204.4 1.0 9.2e-61 203.9 0.7 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIE76116.1 - 1.4e-18 67.5 0.1 2.7e-18 66.6 0.1 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIE76116.1 - 6e-14 51.6 0.3 9.3e-14 51.0 0.2 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EIE76116.1 - 0.0001 21.8 0.5 0.00018 20.9 0.4 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EIE76116.1 - 0.00042 20.2 0.1 0.0007 19.5 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EIE76116.1 - 0.0006 19.0 0.8 0.00099 18.3 0.5 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 EIE76116.1 - 0.00096 19.2 0.0 0.002 18.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain Septin PF00735.13 EIE76116.1 - 0.0038 16.2 0.3 0.3 10.0 0.0 2.1 2 0 0 2 2 2 1 Septin FeoB_N PF02421.13 EIE76116.1 - 0.0091 15.2 0.3 0.072 12.3 0.2 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.5 EIE76116.1 - 0.014 14.6 0.4 0.025 13.7 0.3 1.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_14 PF13173.1 EIE76116.1 - 0.015 15.2 0.2 0.38 10.6 0.2 2.3 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 EIE76116.1 - 0.02 15.1 0.7 2 8.6 0.0 2.9 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EIE76116.1 - 0.02 14.8 0.3 0.051 13.5 0.2 2.0 1 1 1 2 2 2 0 AAA ATPase domain DUF258 PF03193.11 EIE76116.1 - 0.021 14.0 0.4 0.069 12.3 0.0 2.0 2 1 0 2 2 2 0 Protein of unknown function, DUF258 ABC_tran PF00005.22 EIE76116.1 - 0.027 14.7 0.1 0.063 13.5 0.0 1.8 1 1 0 1 1 1 0 ABC transporter PduV-EutP PF10662.4 EIE76116.1 - 0.033 13.6 0.1 0.37 10.2 0.0 2.3 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.1 EIE76116.1 - 0.038 13.5 0.0 0.12 11.9 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 EIE76116.1 - 0.038 13.7 0.1 0.065 12.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF4238 PF14022.1 EIE76116.1 - 0.09 12.0 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4238) LUC7 PF03194.10 EIE76116.1 - 0.17 11.3 1.2 0.23 10.9 0.8 1.1 1 0 0 1 1 1 0 LUC7 N_terminus DUF3533 PF12051.3 EIE76116.1 - 0.19 10.4 0.7 0.22 10.2 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) UPF0240 PF06784.6 EIE76117.1 - 0.031 13.9 0.2 0.031 13.9 0.1 2.6 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0240) DUF4298 PF14131.1 EIE76117.1 - 0.04 13.7 2.4 5.3 6.9 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4298) FBA_3 PF08268.7 EIE76117.1 - 0.12 12.1 0.6 0.17 11.6 0.4 1.3 1 0 0 1 1 1 0 F-box associated domain ATP-synt_E PF05680.7 EIE76117.1 - 0.25 11.3 6.2 1.1 9.2 4.1 2.2 2 0 0 2 2 2 0 ATP synthase E chain Sybindin PF04099.7 EIE76118.1 - 7e-25 87.3 0.4 7.9e-25 87.2 0.3 1.0 1 0 0 1 1 1 1 Sybindin-like family Helicase_C_2 PF13307.1 EIE76120.1 - 1.3e-50 171.6 0.0 2.4e-50 170.7 0.0 1.4 1 0 0 1 1 1 1 Helicase C-terminal domain Robl_LC7 PF03259.12 EIE76121.1 - 1.7e-09 37.1 0.1 4.5e-09 35.7 0.0 1.6 1 1 1 2 2 2 1 Roadblock/LC7 domain RuBisCO_large_N PF02788.11 EIE76121.1 - 0.014 15.0 0.2 0.018 14.7 0.1 1.1 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, N-terminal domain DUF3986 PF13143.1 EIE76121.1 - 0.017 15.5 0.1 0.023 15.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3986) TRAP_alpha PF03896.11 EIE76122.1 - 9.8e-09 34.6 0.0 1.2e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit Minor_capsid_1 PF10665.4 EIE76123.1 - 0.043 13.6 0.3 0.061 13.1 0.2 1.3 1 1 0 1 1 1 0 Minor capsid protein WSK PF03832.8 EIE76123.1 - 0.11 11.8 1.6 0.2 11.0 1.1 1.4 1 0 0 1 1 1 0 WSK motif Zip PF02535.17 EIE76123.1 - 1.1 8.2 3.8 1.2 8.0 2.6 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter CDC50 PF03381.10 EIE76124.1 - 7.6e-59 199.1 4.2 8.9e-59 198.9 2.9 1.0 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DASH_Dad1 PF08649.5 EIE76125.1 - 8.5e-07 28.5 0.2 1e-06 28.3 0.2 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 Occludin_ELL PF07303.8 EIE76125.1 - 0.0015 19.2 1.3 0.0018 18.9 0.9 1.0 1 0 0 1 1 1 1 Occludin homology domain BAR PF03114.13 EIE76125.1 - 0.0027 17.2 0.3 0.0032 17.0 0.2 1.2 1 0 0 1 1 1 1 BAR domain Med29 PF11568.3 EIE76125.1 - 0.031 14.3 0.2 0.038 14.0 0.1 1.2 1 0 0 1 1 1 0 Mediator complex subunit 29 DUF948 PF06103.6 EIE76125.1 - 0.034 13.9 0.1 0.041 13.7 0.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) IncA PF04156.9 EIE76125.1 - 0.064 12.8 0.4 0.075 12.6 0.3 1.1 1 0 0 1 1 1 0 IncA protein TMP_2 PF06791.8 EIE76125.1 - 0.078 12.5 0.1 5.2 6.6 0.1 2.0 1 1 1 2 2 2 0 Prophage tail length tape measure protein Rapamycin_bind PF08771.6 EIE76125.1 - 0.12 12.4 0.8 0.38 10.8 0.1 1.8 1 1 1 2 2 2 0 Rapamycin binding domain PilJ PF13675.1 EIE76125.1 - 0.13 12.5 0.2 0.15 12.3 0.2 1.1 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term Mating_N PF12731.2 EIE76125.1 - 0.14 12.0 0.6 0.18 11.7 0.4 1.3 1 1 0 1 1 1 0 Mating-type protein beta 1 CTP_transf_2 PF01467.21 EIE76126.1 - 2.1e-20 73.3 0.0 3.4e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase Aldo_ket_red PF00248.16 EIE76129.1 - 6e-72 241.8 0.0 7.4e-72 241.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Thioredoxin_6 PF13848.1 EIE76129.1 - 0.059 13.1 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like domain SUFU_C PF12470.3 EIE76129.1 - 0.076 12.6 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Suppressor of Fused Gli/Ci N terminal binding domain WD40 PF00400.27 EIE76130.1 - 0.00025 20.7 3.2 0.73 9.8 0.2 4.1 3 0 0 3 3 3 2 WD domain, G-beta repeat LVIVD PF08309.6 EIE76130.1 - 0.1 11.6 0.2 0.32 10.0 0.0 1.9 2 0 0 2 2 2 0 LVIVD repeat Exo_endo_phos PF03372.18 EIE76131.1 - 1.7e-14 54.3 0.0 2.4e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family UBA_4 PF14555.1 EIE76131.1 - 0.0016 17.9 0.0 0.0035 16.8 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain CorA PF01544.13 EIE76132.1 - 1.6e-47 161.9 7.4 4.1e-47 160.6 5.1 1.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Thioredoxin PF00085.15 EIE76133.1 - 1.2e-64 214.5 5.0 4.4e-34 116.2 0.1 4.6 4 1 0 4 4 4 4 Thioredoxin Thioredoxin_6 PF13848.1 EIE76133.1 - 2.4e-47 161.1 4.8 3.7e-31 108.3 1.0 3.2 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_2 PF13098.1 EIE76133.1 - 2.2e-13 50.3 3.9 0.0029 17.7 0.0 4.8 2 2 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EIE76133.1 - 1.2e-10 41.3 1.1 0.0064 16.5 0.0 4.5 4 1 0 4 4 4 3 Thioredoxin-like Thioredoxin_7 PF13899.1 EIE76133.1 - 1.9e-10 40.6 0.3 0.00084 19.3 0.0 3.6 4 0 0 4 4 4 2 Thioredoxin-like Calsequestrin PF01216.12 EIE76133.1 - 3.6e-07 29.2 5.3 6.3e-07 28.5 0.7 2.4 2 0 0 2 2 2 1 Calsequestrin AhpC-TSA PF00578.16 EIE76133.1 - 6.5e-07 29.0 4.3 0.0062 16.2 0.1 3.5 2 1 1 3 3 3 3 AhpC/TSA family Redoxin PF08534.5 EIE76133.1 - 0.00013 21.5 3.7 1 8.8 0.0 3.5 3 0 0 3 3 3 2 Redoxin ERp29_N PF07912.8 EIE76133.1 - 0.00013 21.8 0.8 0.28 11.0 0.0 3.7 3 1 1 4 4 4 2 ERp29, N-terminal domain Thioredoxin_3 PF13192.1 EIE76133.1 - 0.00069 19.3 0.2 3.8 7.3 0.1 3.5 3 0 0 3 3 3 1 Thioredoxin domain DUF2529 PF10740.4 EIE76133.1 - 0.035 13.5 0.3 0.11 11.9 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2529) Glutaredoxin PF00462.19 EIE76133.1 - 0.079 12.9 5.4 8.4 6.4 0.4 4.2 5 1 0 5 5 4 0 Glutaredoxin Thioredoxin_5 PF13743.1 EIE76133.1 - 0.17 11.4 3.2 0.36 10.3 0.1 3.1 3 2 2 5 5 5 0 Thioredoxin Thioredoxin_4 PF13462.1 EIE76133.1 - 0.39 10.7 5.8 2.7 7.9 1.3 3.3 3 1 0 3 3 3 0 Thioredoxin GPI-anchored PF10342.4 EIE76134.1 - 6.9e-09 36.0 0.1 8.9e-09 35.7 0.1 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.1 EIE76134.1 - 0.004 16.6 0.0 0.0045 16.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) BcsB PF03170.8 EIE76134.1 - 0.084 10.8 0.1 0.099 10.6 0.0 1.0 1 0 0 1 1 1 0 Bacterial cellulose synthase subunit CTP_transf_2 PF01467.21 EIE76135.1 - 6.3e-37 127.0 0.0 2.1e-21 76.6 0.0 2.3 2 0 0 2 2 2 2 Cytidylyltransferase FAD_syn PF06574.7 EIE76135.1 - 1.8e-05 24.4 0.3 0.14 11.7 0.0 2.8 2 1 0 2 2 2 2 FAD synthetase ScdA_N PF04405.9 EIE76135.1 - 0.0052 16.1 0.0 0.012 14.9 0.0 1.6 1 0 0 1 1 1 1 Domain of Unknown function (DUF542) Pantoate_ligase PF02569.10 EIE76135.1 - 0.018 13.7 0.1 1.6 7.4 0.0 2.4 2 0 0 2 2 2 0 Pantoate-beta-alanine ligase CoA_binding_3 PF13727.1 EIE76135.1 - 0.032 14.0 0.0 0.48 10.2 0.0 2.2 2 0 0 2 2 2 0 CoA-binding domain AAA PF00004.24 EIE76136.1 - 1.6e-13 51.0 0.0 2.9e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EIE76136.1 - 1e-10 41.8 0.0 1.9e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EIE76136.1 - 1.8e-05 24.4 0.0 3e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EIE76136.1 - 3.5e-05 23.8 0.1 0.00077 19.4 0.0 2.5 2 1 0 3 3 3 1 AAA ATPase domain DUF2075 PF09848.4 EIE76136.1 - 0.00026 20.0 0.0 0.00038 19.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 EIE76136.1 - 0.00082 18.9 0.0 0.0019 17.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.17 EIE76136.1 - 0.0033 16.3 0.2 0.0057 15.5 0.2 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_11 PF13086.1 EIE76136.1 - 0.0057 16.2 0.1 0.008 15.7 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EIE76136.1 - 0.0068 17.2 0.0 0.012 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.12 EIE76136.1 - 0.0092 15.5 0.2 0.023 14.2 0.1 1.7 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_18 PF13238.1 EIE76136.1 - 0.0093 16.2 0.0 0.021 15.1 0.0 1.7 2 0 0 2 2 1 1 AAA domain NTPase_1 PF03266.10 EIE76136.1 - 0.0097 15.6 0.6 0.18 11.4 0.0 2.3 1 1 0 2 2 2 1 NTPase RNA_helicase PF00910.17 EIE76136.1 - 0.011 15.8 0.0 0.024 14.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Viral_helicase1 PF01443.13 EIE76136.1 - 0.017 14.6 0.0 0.037 13.5 0.0 1.7 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase cobW PF02492.14 EIE76136.1 - 0.018 14.4 0.1 0.042 13.2 0.1 1.7 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Miro PF08477.8 EIE76136.1 - 0.022 15.2 0.0 0.046 14.2 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein Arch_ATPase PF01637.13 EIE76136.1 - 0.03 14.0 0.2 0.13 11.9 0.2 2.0 1 1 0 1 1 1 0 Archaeal ATPase Zeta_toxin PF06414.7 EIE76136.1 - 0.032 13.3 0.0 0.053 12.6 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_14 PF13173.1 EIE76136.1 - 0.037 13.9 0.0 0.067 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EIE76136.1 - 0.056 13.1 0.4 0.52 10.0 0.2 2.6 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) KAP_NTPase PF07693.9 EIE76136.1 - 0.063 12.2 0.3 0.7 8.8 0.0 2.2 1 1 1 2 2 2 0 KAP family P-loop domain AAA_19 PF13245.1 EIE76136.1 - 0.082 12.6 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain DEAD PF00270.24 EIE76136.1 - 0.98 8.8 5.8 0.18 11.2 0.6 2.2 2 1 1 3 3 3 0 DEAD/DEAH box helicase Pribosyl_synth PF14572.1 EIE76137.1 - 6.2e-42 143.4 4.3 3.4e-34 118.1 1.2 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 EIE76137.1 - 7.7e-35 119.1 0.0 2.8e-34 117.3 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 EIE76137.1 - 6.3e-11 42.0 0.1 1.3e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EIE76137.1 - 0.003 16.7 0.1 0.0052 16.0 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase CBM_21 PF03370.8 EIE76138.1 - 4.3e-29 100.7 0.9 6.5e-29 100.1 0.6 1.3 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit CBM_25 PF03423.8 EIE76138.1 - 0.00025 21.0 0.4 0.00049 20.1 0.3 1.5 1 0 0 1 1 1 1 Carbohydrate binding domain (family 25) Wbp11 PF09429.5 EIE76139.1 - 3.6e-17 62.1 10.5 5.2e-17 61.6 7.2 1.3 1 1 0 1 1 1 1 WW domain binding protein 11 DUF4519 PF15012.1 EIE76139.1 - 9.2 6.2 8.7 18 5.3 6.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) Ribosomal_S13_N PF08069.7 EIE76140.1 - 2.2e-31 107.4 0.2 5.1e-31 106.2 0.1 1.6 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 EIE76140.1 - 5.6e-25 86.9 0.3 1.1e-24 86.0 0.1 1.5 2 0 0 2 2 2 1 Ribosomal protein S15 GTP_EFTU PF00009.22 EIE76141.1 - 1.1e-43 148.8 0.0 1.8e-43 148.1 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 EIE76141.1 - 7.9e-25 86.5 0.0 1.9e-24 85.2 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 EIE76141.1 - 2.4e-19 69.0 0.2 3e-18 65.4 0.1 2.3 1 1 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EIE76141.1 - 3.2e-10 39.9 0.4 1.7e-09 37.6 0.1 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_IV PF03764.13 EIE76141.1 - 1.3e-06 28.0 0.1 1.8e-05 24.3 0.1 2.6 1 1 0 1 1 1 1 Elongation factor G, domain IV MMR_HSR1 PF01926.18 EIE76141.1 - 0.012 15.6 0.0 0.037 13.9 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase AIG1 PF04548.11 EIE76141.1 - 0.11 11.5 0.0 0.46 9.5 0.0 1.9 2 0 0 2 2 2 0 AIG1 family Arf PF00025.16 EIE76142.1 - 4e-65 218.3 0.0 4.4e-65 218.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EIE76142.1 - 2.6e-08 33.2 0.0 3.4e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EIE76142.1 - 7.4e-08 31.4 0.1 0.00015 20.5 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.18 EIE76142.1 - 1.8e-06 27.8 0.0 5.7e-06 26.2 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EIE76142.1 - 4.8e-06 27.0 0.0 6.6e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 EIE76142.1 - 1.3e-05 24.6 0.0 1.6e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EIE76142.1 - 2.6e-05 23.4 0.0 2.8e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 EIE76142.1 - 0.014 14.8 0.0 0.051 13.0 0.0 1.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.22 EIE76142.1 - 0.053 12.9 0.0 1.6 8.1 0.0 2.0 1 1 0 2 2 2 0 Elongation factor Tu GTP binding domain zf-H2C2_2 PF13465.1 EIE76143.1 - 4e-14 52.1 22.8 6e-09 35.7 1.6 5.2 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.21 EIE76143.1 - 1.3e-11 44.1 30.1 3.8e-05 23.7 2.1 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIE76143.1 - 3e-09 36.5 28.9 0.00045 20.3 1.4 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EIE76143.1 - 0.0012 18.6 3.8 0.013 15.4 0.3 4.0 4 1 0 4 4 4 2 C2H2-type zinc finger zf-Di19 PF05605.7 EIE76143.1 - 0.01 15.9 2.1 0.01 15.9 1.5 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 EIE76143.1 - 0.012 15.7 12.8 1.4 9.1 0.2 3.7 2 1 1 3 3 3 0 Zinc-finger double-stranded RNA-binding C1_1 PF00130.17 EIE76143.1 - 0.019 14.6 7.8 4.1 7.1 0.3 3.4 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) GCC2_GCC3 PF07699.8 EIE76143.1 - 0.027 14.0 2.8 0.045 13.3 0.6 2.3 2 0 0 2 2 2 0 GCC2 and GCC3 RRN7 PF11781.3 EIE76143.1 - 0.13 11.7 4.4 0.27 10.7 0.1 3.0 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 DUF2256 PF10013.4 EIE76143.1 - 0.92 9.3 7.1 3.1 7.6 0.1 3.5 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-CHCC PF10276.4 EIE76143.1 - 0.93 9.3 6.7 12 5.8 0.1 3.0 3 0 0 3 3 3 0 Zinc-finger domain Mut7-C PF01927.11 EIE76143.1 - 1 9.3 13.4 0.057 13.3 1.2 2.6 1 1 1 2 2 2 0 Mut7-C RNAse domain C1_4 PF07975.7 EIE76143.1 - 1.8 8.6 9.1 11 6.0 1.7 2.6 2 1 0 2 2 2 0 TFIIH C1-like domain zf-met PF12874.2 EIE76143.1 - 1.8 8.8 15.5 0.3 11.3 0.8 3.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EIE76143.1 - 4.7 7.3 19.3 22 5.2 5.2 3.6 2 2 0 2 2 2 0 C2H2 type zinc-finger (2 copies) FGGY_C PF02782.11 EIE76144.1 - 1.7e-71 239.9 0.1 3.2e-71 239.0 0.1 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EIE76144.1 - 1.2e-48 165.5 0.0 1.7e-48 165.0 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain ACT_4 PF13291.1 EIE76144.1 - 0.13 12.5 0.0 6.6 7.1 0.0 2.6 2 0 0 2 2 2 0 ACT domain Atg14 PF10186.4 EIE76146.1 - 0.0019 17.2 5.9 0.0036 16.2 4.0 1.6 1 1 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 HAUS2 PF15003.1 EIE76146.1 - 0.003 16.6 0.9 0.0044 16.1 0.6 1.2 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 2 Zn_Tnp_IS1 PF03811.8 EIE76146.1 - 0.011 15.1 4.2 0.026 14.0 2.9 1.6 1 0 0 1 1 1 0 InsA N-terminal domain DUF3268 PF11672.3 EIE76146.1 - 0.012 15.6 1.7 0.051 13.6 1.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3268) DZR PF12773.2 EIE76146.1 - 0.074 12.8 0.8 0.18 11.6 0.6 1.7 1 0 0 1 1 1 0 Double zinc ribbon Prefoldin PF02996.12 EIE76146.1 - 0.16 11.6 1.6 0.34 10.5 1.1 1.5 1 0 0 1 1 1 0 Prefoldin subunit DUF4094 PF13334.1 EIE76146.1 - 0.33 11.3 2.3 1 9.7 1.6 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4094) Zn_Tnp_IS1595 PF12760.2 EIE76146.1 - 0.35 10.7 4.0 0.66 9.8 2.8 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-DNA_Pol PF08996.5 EIE76146.1 - 0.36 10.1 5.3 0.063 12.6 0.9 1.6 2 0 0 2 2 2 0 DNA Polymerase alpha zinc finger zf-Dof PF02701.10 EIE76146.1 - 0.47 10.3 2.9 0.95 9.4 2.0 1.5 1 0 0 1 1 1 0 Dof domain, zinc finger DUF3279 PF11682.3 EIE76146.1 - 0.64 9.5 4.2 6.4 6.3 0.0 2.9 1 1 1 3 3 3 0 Protein of unknown function (DUF3279) FdhE PF04216.7 EIE76146.1 - 1.4 8.6 9.5 0.058 13.1 0.8 2.1 1 1 1 2 2 2 0 Protein involved in formate dehydrogenase formation zf-FCS PF06467.9 EIE76146.1 - 2.3 7.9 7.1 0.22 11.1 0.8 2.2 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif TFIIA PF03153.8 EIE76146.1 - 8.4 6.1 10.4 11 5.7 7.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-Di19 PF05605.7 EIE76148.1 - 0.046 13.8 1.1 0.089 12.9 0.3 1.8 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-AD PF07776.10 EIE76148.1 - 0.052 13.5 0.5 0.16 11.9 0.4 1.9 1 0 0 1 1 1 0 Zinc-finger associated domain (zf-AD) zf-C2H2_4 PF13894.1 EIE76148.1 - 0.31 11.4 5.3 1.6 9.2 1.2 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger DSPc PF00782.15 EIE76149.1 - 2e-25 88.9 0.5 2e-25 88.9 0.3 3.2 4 0 0 4 4 4 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.15 EIE76149.1 - 3.5e-15 56.3 0.1 1.8e-13 50.8 0.0 2.8 2 0 0 2 2 2 1 Rhodanese-like domain Y_phosphatase2 PF03162.8 EIE76149.1 - 5.2e-05 22.6 0.1 5.2e-05 22.6 0.0 2.3 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 EIE76149.1 - 0.00018 20.9 0.1 0.00018 20.9 0.1 2.1 2 0 0 2 2 2 1 Protein-tyrosine phosphatase BAF1_ABF1 PF04684.8 EIE76149.1 - 0.042 12.7 11.7 0.067 12.0 8.1 1.4 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Y_phosphatase3 PF13350.1 EIE76149.1 - 0.057 13.6 3.0 0.1 12.8 0.0 2.8 3 0 0 3 3 3 0 Tyrosine phosphatase family PTPlike_phytase PF14566.1 EIE76149.1 - 1.7 8.6 8.2 13 5.7 5.6 2.6 1 1 0 1 1 1 0 Inositol hexakisphosphate PMT PF02366.13 EIE76150.1 - 4.3e-47 160.5 5.8 4.7e-47 160.4 4.0 1.0 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_2 PF13231.1 EIE76150.1 - 0.00084 19.2 4.1 0.00084 19.2 2.8 1.5 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EIE76151.1 - 3.3e-33 114.8 0.1 4.3e-33 114.4 0.1 1.1 1 0 0 1 1 1 1 MIR domain YwiC PF14256.1 EIE76151.1 - 0.15 12.1 5.6 0.24 11.5 3.9 1.3 1 0 0 1 1 1 0 YwiC-like protein G-alpha PF00503.15 EIE76154.1 - 3.8e-50 170.7 0.0 4.4e-50 170.4 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EIE76154.1 - 0.0027 16.9 0.0 0.049 12.8 0.0 2.2 2 0 0 2 2 2 1 ADP-ribosylation factor family p450 PF00067.17 EIE76155.1 - 7.5e-40 136.8 0.0 9.5e-40 136.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MMS22L_N PF14910.1 EIE76156.1 - 0.075 11.2 0.5 0.09 11.0 0.3 1.0 1 0 0 1 1 1 0 S-phase genomic integrity recombination mediator, N-terminal DUF4564 PF15169.1 EIE76157.1 - 0.93 9.1 4.1 0.68 9.6 1.6 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4564) FAM177 PF14774.1 EIE76157.1 - 1.5 8.7 6.9 0.87 9.5 3.7 1.4 2 0 0 2 2 2 0 FAM177 family RVT_1 PF00078.22 EIE76159.1 - 8.6e-21 74.2 0.0 1.1e-20 73.8 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) p450 PF00067.17 EIE76162.1 - 3.1e-50 171.0 0.0 3.4e-50 170.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF87 PF01935.12 EIE76163.1 - 0.016 15.0 1.3 0.071 12.9 0.7 1.9 1 1 1 2 2 2 0 Domain of unknown function DUF87 tRNA-synt_1g PF09334.6 EIE76164.1 - 2.2e-89 299.8 0.4 3.6e-89 299.1 0.3 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EIE76164.1 - 1e-16 60.1 2.4 3.1e-13 48.5 0.0 3.1 1 1 2 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 EIE76164.1 - 1.1e-07 31.2 0.6 0.00093 18.4 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.8 EIE76164.1 - 0.00034 20.4 1.1 0.00048 19.9 0.0 1.7 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA DUF1949 PF09186.6 EIE76164.1 - 0.071 12.7 0.0 0.19 11.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1949) DALR_1 PF05746.10 EIE76164.1 - 0.13 12.1 0.1 0.31 10.9 0.1 1.6 1 0 0 1 1 1 0 DALR anticodon binding domain DUF723 PF05265.8 EIE76165.1 - 0.032 14.0 0.0 0.047 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF723) RVT_1 PF00078.22 EIE76166.1 - 0.046 13.0 0.0 0.058 12.7 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Bromodomain PF00439.20 EIE76167.1 - 3.7e-07 29.9 0.1 0.00028 20.7 0.0 2.8 1 1 1 2 2 2 2 Bromodomain Myb_DNA-bind_6 PF13921.1 EIE76167.1 - 0.02 14.9 0.2 0.051 13.6 0.1 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EIE76167.1 - 0.11 12.5 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain Chs3p PF12271.3 EIE76168.1 - 4.8e-98 327.7 23.4 3.6e-80 269.0 11.6 2.0 1 1 1 2 2 2 2 Chitin synthase III catalytic subunit XRN_N PF03159.13 EIE76169.1 - 1.2e-50 172.1 0.1 1.4e-29 103.1 0.0 2.4 1 1 1 2 2 2 2 XRN 5'-3' exonuclease N-terminus Glyco_hydro_63 PF03200.11 EIE76170.1 - 1.1e-225 751.1 1.8 6.4e-224 745.3 1.3 2.0 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase Trehalase PF01204.13 EIE76170.1 - 0.00046 18.9 0.0 0.00077 18.2 0.0 1.2 1 0 0 1 1 1 1 Trehalase GDE_C PF06202.9 EIE76170.1 - 0.0061 15.3 0.0 0.011 14.5 0.0 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase G-alpha PF00503.15 EIE76171.1 - 2.4e-129 431.4 4.6 2.8e-129 431.1 3.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EIE76171.1 - 4.6e-16 58.5 4.5 6.1e-12 45.1 0.3 2.7 2 1 0 2 2 2 2 ADP-ribosylation factor family Miro PF08477.8 EIE76171.1 - 0.0003 21.2 0.1 0.56 10.7 0.0 2.8 2 1 0 2 2 2 2 Miro-like protein Gtr1_RagA PF04670.7 EIE76171.1 - 0.0029 16.7 6.6 0.019 14.0 0.2 2.8 1 1 1 2 2 2 2 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EIE76171.1 - 0.0043 16.9 0.1 1.7 8.6 0.0 2.4 1 1 1 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.1 EIE76171.1 - 0.012 15.1 0.0 0.025 14.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 EIE76171.1 - 0.021 14.2 0.0 0.051 13.0 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family GTP_EFTU PF00009.22 EIE76171.1 - 0.022 14.2 0.0 1.6 8.1 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.12 EIE76171.1 - 0.071 12.6 0.5 16 4.9 0.0 2.8 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein DDE_3 PF13358.1 EIE76173.1 - 7e-22 77.7 0.0 1.3e-21 76.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease ATP-synt_F PF01990.12 EIE76174.1 - 0.66 10.3 2.9 2.7 8.4 0.2 2.3 2 0 0 2 2 2 0 ATP synthase (F/14-kDa) subunit DDE_3 PF13358.1 EIE76175.1 - 7e-22 77.7 0.0 1.3e-21 76.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Sugar_tr PF00083.19 EIE76176.1 - 9.4e-125 416.7 28.7 1.1e-124 416.5 19.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIE76176.1 - 7.6e-30 103.8 52.2 3e-25 88.7 14.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1688 PF07958.6 EIE76177.1 - 1.2e-132 442.4 0.0 1.4e-132 442.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) bZIP_1 PF00170.16 EIE76178.1 - 6.7e-09 35.5 23.8 4.9e-08 32.8 13.4 2.7 2 1 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EIE76178.1 - 3.9e-06 26.5 15.3 3.7e-05 23.4 3.6 2.6 2 0 0 2 2 2 2 Basic region leucine zipper ACCA PF03255.9 EIE76178.1 - 0.00021 20.8 2.2 0.00043 19.8 1.5 1.5 1 0 0 1 1 1 1 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF1993 PF09351.5 EIE76178.1 - 0.00087 19.2 1.8 0.0013 18.6 0.5 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1993) DUF2216 PF10226.4 EIE76178.1 - 0.00093 18.7 1.3 0.0011 18.5 0.1 1.6 2 0 0 2 2 2 1 Uncharacterized conserved proteins (DUF2216) PAP1 PF08601.5 EIE76178.1 - 0.0018 18.0 0.1 0.0018 18.0 0.1 2.8 2 1 0 2 2 2 1 Transcription factor PAP1 Lyase_aromatic PF00221.14 EIE76178.1 - 0.0025 16.3 0.4 0.0036 15.8 0.3 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase Striatin PF08232.7 EIE76178.1 - 0.0088 16.3 2.6 0.0088 16.3 1.8 2.0 1 1 1 2 2 2 1 Striatin family MerR-DNA-bind PF09278.6 EIE76178.1 - 0.091 13.1 7.9 0.9 9.9 2.1 3.1 2 1 1 3 3 3 0 MerR, DNA binding DUF3972 PF13118.1 EIE76178.1 - 0.21 11.6 6.8 0.72 9.9 1.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3972) DivIC PF04977.10 EIE76178.1 - 0.27 10.7 9.6 1.2 8.7 1.5 2.5 1 1 1 2 2 2 0 Septum formation initiator Atg14 PF10186.4 EIE76178.1 - 0.38 9.6 8.4 0.67 8.8 5.8 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 EIE76178.1 - 0.47 10.0 8.1 0.09 12.3 3.2 1.5 2 0 0 2 2 2 0 IncA protein Rho_Binding PF08912.6 EIE76178.1 - 0.66 10.3 13.3 0.62 10.4 1.5 2.9 3 0 0 3 3 3 0 Rho Binding TSC22 PF01166.13 EIE76178.1 - 0.92 9.5 5.9 2.2 8.3 1.6 2.5 1 1 1 2 2 2 0 TSC-22/dip/bun family PRELI PF04707.9 EIE76179.1 - 7.5e-34 116.5 1.6 7.4e-33 113.3 1.1 1.9 1 1 0 1 1 1 1 PRELI-like family Bac_DnaA PF00308.13 EIE76179.1 - 0.04 13.5 0.1 0.22 11.1 0.0 1.8 1 1 1 2 2 2 0 Bacterial dnaA protein Toxin_R_bind_N PF07953.7 EIE76179.1 - 0.08 12.4 1.0 1.3 8.4 0.1 2.3 2 0 0 2 2 2 0 Clostridium neurotoxin, N-terminal receptor binding KH_1 PF00013.24 EIE76181.1 - 7.4e-06 25.5 0.6 1.8e-05 24.3 0.4 1.6 1 0 0 1 1 1 1 KH domain K1377 PF15352.1 EIE76181.1 - 0.11 10.4 0.5 0.13 10.1 0.3 1.1 1 0 0 1 1 1 0 Susceptibility to monomelic amyotrophy THF_DHG_CYH PF00763.18 EIE76182.1 - 2.4e-18 66.2 0.0 3.7e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 EIE76182.1 - 7.7e-13 47.8 0.1 1.8e-11 43.3 0.1 2.7 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 2-Hacid_dh_C PF02826.14 EIE76182.1 - 0.025 13.7 0.0 0.04 13.0 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SBP_bac_5 PF00496.17 EIE76182.1 - 0.044 12.6 0.0 0.063 12.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle TrkA_C PF02080.16 EIE76182.1 - 0.066 12.8 0.0 0.16 11.5 0.0 1.7 1 1 0 1 1 1 0 TrkA-C domain AAA_5 PF07728.9 EIE76183.1 - 0.00064 19.4 1.1 0.0012 18.6 0.7 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) BSP_II PF05432.6 EIE76183.1 - 0.0013 18.1 0.6 0.0013 18.1 0.4 1.7 2 0 0 2 2 2 1 Bone sialoprotein II (BSP-II) Syntaxin-18_N PF10496.4 EIE76183.1 - 0.87 9.4 7.0 0.17 11.7 1.1 2.7 2 1 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus Sds3 PF08598.6 EIE76183.1 - 0.99 8.8 18.6 0.29 10.6 0.3 2.9 1 1 1 3 3 3 0 Sds3-like Ribosomal_S8 PF00410.14 EIE76184.1 - 2e-27 95.5 0.0 2.8e-27 95.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 LAGLIDADG_WhiA PF14527.1 EIE76184.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 WhiA LAGLIDADG-like domain Cylicin_N PF15241.1 EIE76185.1 - 0.091 12.6 0.1 0.12 12.2 0.1 1.2 1 0 0 1 1 1 0 Cylicin N-terminus RasGEF PF00617.14 EIE76186.1 - 1.4e-37 129.2 1.2 3.3e-37 128.0 0.8 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EIE76186.1 - 2.2e-16 59.8 4.4 2.2e-16 59.8 3.1 2.5 2 1 0 2 2 2 1 RasGEF N-terminal motif CHCH PF06747.8 EIE76187.1 - 5.4e-07 29.3 6.4 7.8e-07 28.8 4.4 1.3 1 0 0 1 1 1 1 CHCH domain DUF4319 PF14203.1 EIE76187.1 - 0.0074 15.8 0.1 0.011 15.2 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4319) Cmc1 PF08583.5 EIE76187.1 - 0.0085 15.8 0.9 0.0085 15.8 0.6 2.0 1 1 2 3 3 3 1 Cytochrome c oxidase biogenesis protein Cmc1 like EpoR_lig-bind PF09067.5 EIE76187.1 - 0.024 14.6 2.5 0.03 14.2 1.7 1.3 1 1 0 1 1 1 0 Erythropoietin receptor, ligand binding Beta-Casp PF10996.3 EIE76188.1 - 2.1e-27 95.5 0.0 4.8e-27 94.3 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.7 EIE76188.1 - 3.6e-06 26.6 0.0 6.9e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_2 PF12706.2 EIE76188.1 - 6.7e-05 22.5 0.1 0.00014 21.4 0.1 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain CPSF100_C PF13299.1 EIE76188.1 - 0.00037 20.7 0.0 0.00098 19.3 0.0 1.7 1 0 0 1 1 1 1 Cleavage and polyadenylation factor 2 C-terminal MepB PF08877.5 EIE76188.1 - 0.0068 15.9 0.0 0.016 14.7 0.0 1.5 1 0 0 1 1 1 1 MepB protein Aldedh PF00171.17 EIE76189.1 - 9.4e-137 456.1 0.8 1e-136 455.9 0.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EIE76189.1 - 0.00057 19.1 0.0 0.16 11.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) MS_channel PF00924.13 EIE76191.1 - 1.7e-20 73.2 3.1 6.2e-19 68.1 0.3 2.5 2 0 0 2 2 2 2 Mechanosensitive ion channel EF-hand_1 PF00036.27 EIE76191.1 - 4.9e-06 25.4 0.1 1.3e-05 24.1 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 EIE76191.1 - 6.4e-05 22.5 0.1 0.0002 20.9 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.1 EIE76191.1 - 0.00023 20.3 0.2 0.00059 19.0 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 EIE76191.1 - 0.003 17.6 0.1 0.0084 16.2 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 EIE76191.1 - 0.0072 15.9 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair DUF2244 PF10003.4 EIE76191.1 - 0.16 11.3 1.8 2 7.7 1.3 2.8 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) Homeobox PF00046.24 EIE76192.1 - 8e-20 70.2 1.8 2.4e-19 68.6 1.3 1.9 1 0 0 1 1 1 1 Homeobox domain HTH_23 PF13384.1 EIE76192.1 - 0.044 13.4 0.3 0.099 12.3 0.2 1.5 1 0 0 1 1 1 0 Homeodomain-like domain Methyltransf_11 PF08241.7 EIE76194.1 - 3.2e-11 43.5 0.0 5.2e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIE76194.1 - 1e-10 41.5 0.0 1.5e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIE76194.1 - 1.1e-09 38.0 0.0 1.7e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIE76194.1 - 8.4e-09 36.0 0.0 1.4e-08 35.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIE76194.1 - 8.5e-07 28.3 0.0 1.4e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EIE76194.1 - 1.3e-06 28.8 0.0 2.3e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIE76194.1 - 2.5e-05 24.5 0.0 3.9e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.13 EIE76194.1 - 0.00016 21.0 0.0 0.00028 20.2 0.0 1.3 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain Methyltransf_4 PF02390.12 EIE76194.1 - 0.0069 15.4 0.0 0.025 13.6 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase CMAS PF02353.15 EIE76194.1 - 0.013 14.5 0.0 0.019 14.0 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase TehB PF03848.9 EIE76194.1 - 0.097 11.8 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB MTS PF05175.9 EIE76194.1 - 0.17 11.2 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Etmic-2 PF06670.6 EIE76195.1 - 0.33 9.6 3.4 0.54 8.9 2.3 1.5 1 0 0 1 1 1 0 Microneme protein Etmic-2 NUP50 PF08911.6 EIE76195.1 - 0.66 10.3 4.0 23 5.4 2.8 2.7 1 1 0 1 1 1 0 NUP50 (Nucleoporin 50 kDa) Ank PF00023.25 EIE76196.1 - 1.1e-20 72.3 1.4 1.5e-08 34.0 0.1 3.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.2 EIE76196.1 - 5e-20 71.6 0.8 5.5e-19 68.2 0.5 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EIE76196.1 - 3.8e-17 60.6 0.4 3.6e-06 26.6 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 EIE76196.1 - 2.7e-15 56.0 1.1 1.1e-09 38.1 0.0 3.0 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 EIE76196.1 - 1.1e-14 54.4 0.3 6.2e-09 36.1 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeats (many copies) WD40 PF00400.27 EIE76197.1 - 2e-62 204.9 16.1 3.3e-13 48.9 0.1 5.2 5 0 0 5 5 5 5 WD domain, G-beta repeat eIF2A PF08662.6 EIE76197.1 - 8.2e-10 38.7 0.3 8.5e-08 32.1 0.0 2.2 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EIE76197.1 - 2.3e-06 26.0 2.3 0.11 10.6 0.0 3.6 1 1 3 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EIE76197.1 - 0.00018 20.4 2.5 0.62 8.7 1.7 3.7 1 1 2 3 3 3 2 Nup133 N terminal like Apc4_WD40 PF12894.2 EIE76197.1 - 0.028 13.9 0.0 14 5.2 0.0 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain DUF3312 PF11768.3 EIE76197.1 - 0.034 12.3 0.0 0.049 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) DUF1513 PF07433.6 EIE76197.1 - 0.13 11.1 0.1 4.7 6.0 0.0 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1513) Aldedh PF00171.17 EIE76198.1 - 2.7e-162 540.2 0.8 3.1e-162 540.1 0.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Synaptobrevin PF00957.16 EIE76199.1 - 2.3e-31 107.2 1.7 2.9e-31 106.9 1.2 1.1 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 EIE76199.1 - 6.2e-12 44.9 0.0 1e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain CotH PF08757.6 EIE76200.1 - 7.2e-48 163.4 2.0 1.3e-47 162.6 1.4 1.4 1 0 0 1 1 1 1 CotH protein Pam16 PF03656.8 EIE76200.1 - 4.4e-30 104.0 3.9 8.2e-30 103.2 2.7 1.4 1 0 0 1 1 1 1 Pam16 VLPT PF07122.6 EIE76201.1 - 0.33 10.6 0.2 0.33 10.6 0.1 1.9 2 0 0 2 2 2 0 Variable length PCR target protein (VLPT) zf-C2H2_2 PF12756.2 EIE76202.1 - 7.3e-07 29.2 0.8 1.7e-06 28.0 0.5 1.7 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) Ion_trans PF00520.26 EIE76202.1 - 0.00044 19.5 4.5 0.00044 19.5 3.1 2.0 2 0 0 2 2 2 1 Ion transport protein Iron_permease PF04120.7 EIE76202.1 - 0.028 13.9 0.4 0.068 12.7 0.3 1.7 1 0 0 1 1 1 0 Low affinity iron permease DUF3484 PF11983.3 EIE76203.1 - 0.24 12.2 3.2 0.48 11.2 2.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3484) BACON PF13004.2 EIE76203.1 - 0.69 10.1 9.8 0.9 9.8 3.3 2.2 1 1 1 2 2 2 0 Bacteroidetes-Associated Carbohydrate-binding Often N-terminal PWI PF01480.12 EIE76204.1 - 0.0025 17.8 0.0 0.0069 16.4 0.0 1.7 1 0 0 1 1 1 1 PWI domain LEF-9 PF05094.7 EIE76204.1 - 0.0031 15.9 0.1 0.0049 15.3 0.1 1.3 1 0 0 1 1 1 1 Late expression factor 9 (LEF-9) KKLCAg1 PF15204.1 EIE76204.1 - 0.043 13.8 2.3 0.046 13.7 0.4 1.8 2 1 1 3 3 3 0 Kita-kyushu lung cancer antigen 1 Aldo_ket_red PF00248.16 EIE76206.1 - 2.3e-56 190.6 0.0 2.7e-56 190.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Arrestin_N PF00339.24 EIE76207.1 - 2.4e-16 59.9 0.0 7.8e-16 58.2 0.0 1.9 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EIE76207.1 - 6.1e-07 29.6 0.0 0.00081 19.5 0.0 2.5 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.2 EIE76207.1 - 0.0067 15.9 0.0 0.028 13.9 0.0 1.9 2 1 0 2 2 2 1 Arrestin_N terminal like SURF4 PF02077.10 EIE76209.1 - 7.4e-79 264.8 10.8 8.9e-79 264.6 7.5 1.0 1 0 0 1 1 1 1 SURF4 family SH PF01445.12 EIE76209.1 - 1.1 8.9 4.5 5.3 6.7 0.3 2.9 2 0 0 2 2 2 0 Viral small hydrophobic protein BRCT PF00533.21 EIE76210.1 - 1.9e-18 66.3 2.8 2.1e-08 34.1 0.1 3.3 3 0 0 3 3 3 3 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EIE76210.1 - 2.9e-16 59.0 0.7 3.8e-12 45.8 0.0 3.0 3 0 0 3 3 3 2 twin BRCT domain Glyco_hydro_18 PF00704.23 EIE76212.1 - 9.9e-17 61.3 0.0 1.5e-16 60.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Sld5 PF05916.6 EIE76212.1 - 1.8e-09 37.8 0.0 6.3e-09 36.1 0.0 2.0 2 0 0 2 2 2 1 GINS complex protein bZIP_1 PF00170.16 EIE76214.1 - 3.7e-10 39.5 7.5 5.7e-10 38.9 5.2 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EIE76214.1 - 0.00022 20.9 6.9 0.0004 20.1 4.8 1.5 1 0 0 1 1 1 1 Basic region leucine zipper Aft1_OSA PF11785.3 EIE76214.1 - 0.00039 20.8 8.5 0.00056 20.3 1.2 2.9 3 0 0 3 3 3 1 Aft1 osmotic stress response (OSM) domain UPF0449 PF15136.1 EIE76214.1 - 0.0079 16.3 0.3 0.013 15.6 0.2 1.4 1 0 0 1 1 1 1 Uncharacterised protein family UPF0449 HALZ PF02183.13 EIE76214.1 - 0.013 15.2 5.0 0.023 14.4 3.5 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper bZIP_Maf PF03131.12 EIE76214.1 - 0.014 15.6 3.9 0.026 14.7 2.7 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor KLRAQ PF10205.4 EIE76214.1 - 0.046 13.7 3.3 0.065 13.2 2.3 1.2 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein IncA PF04156.9 EIE76214.1 - 0.048 13.2 3.7 0.054 13.0 2.5 1.1 1 0 0 1 1 1 0 IncA protein Synaptobrevin PF00957.16 EIE76214.1 - 0.051 13.1 1.3 0.084 12.4 0.9 1.3 1 0 0 1 1 1 0 Synaptobrevin DUF4275 PF14101.1 EIE76214.1 - 0.24 11.4 1.9 0.3 11.1 1.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4275) Ribosomal_L29 PF00831.18 EIE76214.1 - 0.28 10.9 2.3 0.49 10.1 1.6 1.4 1 0 0 1 1 1 0 Ribosomal L29 protein DivIC PF04977.10 EIE76214.1 - 0.74 9.3 4.7 1.3 8.5 3.2 1.4 1 0 0 1 1 1 0 Septum formation initiator SAPS PF04499.10 EIE76215.1 - 5.7e-114 381.3 8.7 2.1e-66 224.5 2.9 4.1 3 2 1 4 4 4 2 SIT4 phosphatase-associated protein SE PF08491.5 EIE76216.1 - 3e-96 321.4 0.1 3.9e-96 321.0 0.1 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.14 EIE76216.1 - 1.1e-14 54.2 0.0 1.7e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EIE76216.1 - 4.4e-11 42.2 0.0 4.5e-06 25.8 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase GIDA PF01134.17 EIE76216.1 - 7.2e-07 28.4 0.3 1.2e-06 27.6 0.2 1.3 1 1 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 EIE76216.1 - 7.7e-07 28.3 1.5 0.0013 17.6 0.4 2.1 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.12 EIE76216.1 - 3.5e-06 26.3 0.1 0.00053 19.1 0.0 2.2 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.22 EIE76216.1 - 0.00011 22.4 0.5 0.001 19.4 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EIE76216.1 - 0.00012 21.3 0.1 0.00017 20.8 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIE76216.1 - 0.00021 21.2 0.4 0.00046 20.1 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EIE76216.1 - 0.00088 19.2 0.1 0.0013 18.6 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EIE76216.1 - 0.0019 18.2 0.0 0.004 17.2 0.0 1.7 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 EIE76216.1 - 0.0051 16.4 0.4 0.016 14.8 0.1 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 EIE76216.1 - 0.014 13.8 0.0 0.022 13.2 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein GDI PF00996.13 EIE76216.1 - 0.017 13.4 0.1 0.064 11.5 0.0 1.9 2 0 0 2 2 2 0 GDP dissociation inhibitor Lycopene_cycl PF05834.7 EIE76216.1 - 0.035 13.0 0.5 0.4 9.5 0.2 2.3 3 0 0 3 3 3 0 Lycopene cyclase protein ThiF PF00899.16 EIE76216.1 - 0.042 13.6 0.2 0.77 9.5 0.0 2.2 2 0 0 2 2 2 0 ThiF family Trp_halogenase PF04820.9 EIE76216.1 - 0.097 11.2 1.7 3.8 6.0 0.0 2.2 1 1 1 2 2 2 0 Tryptophan halogenase NAD_binding_7 PF13241.1 EIE76216.1 - 0.15 12.3 0.1 2.2 8.5 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding DUF3250 PF11618.3 EIE76217.1 - 0.1 12.7 0.3 0.24 11.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3250) IF4E PF01652.13 EIE76218.1 - 0.00035 20.1 0.0 0.00037 20.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E AAA_3 PF07726.6 EIE76219.1 - 0.00099 18.7 0.0 0.0015 18.1 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EIE76219.1 - 0.012 15.3 0.1 0.023 14.4 0.1 1.4 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) Peptidase_S10 PF00450.17 EIE76220.1 - 4.8e-128 427.8 0.9 5.9e-128 427.5 0.6 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Phage_Coat_Gp8 PF05371.7 EIE76221.1 - 0.014 14.9 0.4 0.034 13.6 0.3 1.6 1 0 0 1 1 1 0 Phage major coat protein, Gp8 DUF4199 PF13858.1 EIE76221.1 - 0.022 14.6 2.2 0.022 14.6 1.5 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4199) Dimer_Tnp_Tn5 PF02281.11 EIE76221.1 - 0.053 13.6 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Transposase Tn5 dimerisation domain HlyIII PF03006.15 EIE76221.1 - 0.11 11.8 5.7 0.19 11.1 0.2 2.1 2 0 0 2 2 2 0 Haemolysin-III related PIRT PF15099.1 EIE76221.1 - 0.11 11.6 1.6 0.16 11.1 0.3 1.8 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family Tmemb_14 PF03647.8 EIE76221.1 - 0.12 12.8 4.9 0.64 10.4 0.3 2.4 2 0 0 2 2 2 0 Transmembrane proteins 14C DUF4231 PF14015.1 EIE76221.1 - 0.72 9.8 6.3 1.1 9.3 0.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) DUF3784 PF12650.2 EIE76221.1 - 4.6 7.2 16.8 0.27 11.1 3.3 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF3784) DUF3278 PF11683.3 EIE76221.1 - 6.3 6.7 8.1 0.38 10.7 1.2 2.1 2 2 0 2 2 2 0 Protein of unknown function (DUF3278) DUF3671 PF12420.3 EIE76221.1 - 7.5 6.5 16.6 0.12 12.3 3.2 2.9 2 1 0 3 3 3 0 Protein of unknown function DUF2207 PF09972.4 EIE76221.1 - 8.3 4.8 7.7 0.12 10.8 0.4 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) FGE-sulfatase PF03781.11 EIE76222.1 - 9.9e-27 93.9 3.0 1.1e-25 90.5 1.1 2.2 1 1 1 2 2 2 2 Sulfatase-modifying factor enzyme 1 tRNA-synt_1b PF00579.20 EIE76223.1 - 7e-64 215.7 0.0 9.1e-64 215.3 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) PUCC PF03209.10 EIE76224.1 - 0.0028 16.4 1.5 0.0073 15.0 0.1 2.4 3 0 0 3 3 3 1 PUCC protein DUF1269 PF06897.7 EIE76224.1 - 0.038 14.0 0.0 0.11 12.5 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) MFS_1 PF07690.11 EIE76224.1 - 0.041 12.5 15.1 0.0079 14.9 4.7 2.5 1 1 1 2 2 2 0 Major Facilitator Superfamily Sugar_tr PF00083.19 EIE76224.1 - 0.064 11.8 7.4 0.044 12.3 4.1 1.5 2 0 0 2 2 2 0 Sugar (and other) transporter DUF438 PF04282.8 EIE76224.1 - 0.092 12.5 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF438) Spc97_Spc98 PF04130.8 EIE76227.1 - 1.4e-33 116.0 7.0 1.8e-33 115.7 4.9 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family PFU PF09070.6 EIE76228.1 - 1.1e-38 131.8 0.5 2.2e-38 130.8 0.4 1.6 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.27 EIE76228.1 - 1.7e-30 103.7 7.6 5.1e-08 32.4 0.2 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat PUL PF08324.6 EIE76228.1 - 2.4e-25 88.8 0.3 3.4e-25 88.3 0.2 1.1 1 0 0 1 1 1 1 PUL domain BBS2_Mid PF14783.1 EIE76228.1 - 0.00025 20.8 0.0 0.0035 17.1 0.0 2.4 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.3 EIE76228.1 - 0.0024 16.0 3.2 0.032 12.3 0.0 2.8 2 1 0 3 3 3 1 Nucleoporin Nup120/160 DUF3658 PF12395.3 EIE76228.1 - 0.16 11.5 0.5 7.9 6.0 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function Myosin_head PF00063.16 EIE76229.1 - 2.3e-209 696.9 3.8 2.3e-209 696.9 2.7 2.1 2 0 0 2 2 2 1 Myosin head (motor domain) DUF3584 PF12128.3 EIE76229.1 - 0.0053 14.1 46.0 0.0099 13.2 31.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) IQ PF00612.22 EIE76229.1 - 3.4 7.5 7.3 0.79 9.5 1.3 2.4 2 0 0 2 2 2 0 IQ calmodulin-binding motif TFIID_20kDa PF03847.8 EIE76230.1 - 5.2e-35 119.5 0.6 9.9e-35 118.6 0.4 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.18 EIE76230.1 - 1.3e-05 25.1 0.2 4e-05 23.5 0.1 1.8 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EIE76230.1 - 7.8e-05 22.7 0.1 0.00017 21.6 0.1 1.6 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CCDC-167 PF15188.1 EIE76230.1 - 0.0096 15.8 1.4 0.027 14.4 1.0 1.7 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 167 PDZ_2 PF13180.1 EIE76230.1 - 0.027 14.3 0.0 0.059 13.2 0.0 1.6 1 0 0 1 1 1 0 PDZ domain DUF1515 PF07439.6 EIE76230.1 - 1.1 9.1 4.7 12 5.8 0.7 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1515) Med15 PF09606.5 EIE76230.1 - 3.2 5.8 65.1 4.3 5.4 45.1 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Myb_DNA-bind_6 PF13921.1 EIE76231.1 - 2.9e-06 27.2 1.7 3.8e-05 23.7 0.1 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EIE76231.1 - 0.04 13.9 1.8 5.9 7.0 0.1 2.7 2 1 0 2 2 2 0 Myb-like DNA-binding domain KOW PF00467.24 EIE76233.1 - 1.8e-05 24.2 0.7 3.6e-05 23.3 0.5 1.5 1 0 0 1 1 1 1 KOW motif KOW PF00467.24 EIE76234.1 - 7.2e-11 41.3 2.8 7.2e-11 41.3 1.9 1.7 2 1 0 2 2 2 1 KOW motif DUF1442 PF07279.6 EIE76234.1 - 0.045 12.8 0.9 0.056 12.5 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1442) TFIIS_M PF07500.9 EIE76237.1 - 2.3e-26 92.1 0.6 3.8e-26 91.4 0.1 1.6 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 EIE76237.1 - 4e-20 71.1 8.2 6.9e-20 70.3 5.6 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 EIE76237.1 - 7.4e-12 44.5 6.1 8.9e-12 44.3 2.4 2.1 2 0 0 2 2 2 1 TFIIS helical bundle-like domain LEDGF PF11467.3 EIE76237.1 - 1.6e-08 34.2 0.3 3.8e-08 32.9 0.2 1.6 1 0 0 1 1 1 1 Lens epithelium-derived growth factor (LEDGF) RE_XcyI PF09571.5 EIE76237.1 - 0.053 12.3 0.1 0.079 11.8 0.0 1.2 1 0 0 1 1 1 0 XcyI restriction endonuclease Chitin_synth_1 PF01644.12 EIE76238.1 - 1.4e-83 278.6 0.5 2e-83 278.1 0.4 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EIE76238.1 - 1.3e-26 92.0 0.1 3.4e-26 90.7 0.1 1.7 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EIE76238.1 - 7e-21 74.2 0.0 1e-20 73.6 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 EIE76238.1 - 6.9e-08 32.4 0.0 1e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EIE76238.1 - 1.2e-06 28.5 0.0 2.1e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 DUF2269 PF10027.4 EIE76239.1 - 0.15 11.8 2.0 0.32 10.7 0.0 2.0 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2269) MMS19_N PF14500.1 EIE76241.1 - 0.0069 15.6 0.0 0.0078 15.4 0.0 1.0 1 0 0 1 1 1 1 Dos2-interacting transcription regulator of RNA-Pol-II DUF3393 PF11873.3 EIE76241.1 - 0.03 13.8 0.3 0.036 13.5 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3393) Cyt-b5 PF00173.23 EIE76242.1 - 2e-25 88.3 0.3 2.4e-25 88.1 0.2 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Barwin PF00967.12 EIE76243.1 - 0.00051 19.6 0.7 0.00071 19.2 0.4 1.3 1 1 0 1 1 1 1 Barwin family DPBB_1 PF03330.13 EIE76243.1 - 0.0016 18.4 0.3 0.0023 17.8 0.2 1.4 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel SRF-TF PF00319.13 EIE76244.1 - 3.6e-23 80.5 0.2 6.2e-23 79.7 0.1 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Med15_fungi PF05397.7 EIE76245.1 - 1.3e-22 79.9 0.5 1.3e-22 79.9 0.3 8.4 7 2 2 9 9 9 1 Mediator complex subunit 15 Asparaginase PF00710.15 EIE76246.1 - 8.4e-102 340.2 0.0 1.1e-101 339.8 0.0 1.2 1 0 0 1 1 1 1 Asparaginase Ank_2 PF12796.2 EIE76246.1 - 1.1e-24 86.6 0.1 7.6e-18 64.6 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EIE76246.1 - 2.3e-18 66.1 1.5 6.3e-08 32.9 0.0 4.5 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EIE76246.1 - 8.5e-17 60.8 0.3 2.6e-10 40.1 0.0 4.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 EIE76246.1 - 5.5e-16 57.4 4.9 4.9e-09 35.5 0.0 4.6 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.1 EIE76246.1 - 2.6e-13 48.8 3.3 5.6e-05 23.0 0.1 5.7 5 0 0 5 5 5 3 Ankyrin repeat zf-DNL PF05180.7 EIE76246.1 - 0.091 12.4 0.1 0.26 11.0 0.0 1.7 1 0 0 1 1 1 0 DNL zinc finger CNH PF00780.17 EIE76247.1 - 1.5e-55 188.5 0.2 2.2e-54 184.7 0.0 2.7 3 0 0 3 3 3 1 CNH domain PH_5 PF15405.1 EIE76247.1 - 3.7e-39 133.7 0.0 1.1e-38 132.2 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 EIE76247.1 - 6.2e-37 127.2 0.2 1.7e-36 125.8 0.1 1.8 2 0 0 2 2 2 1 RhoGEF domain DEP PF00610.16 EIE76247.1 - 4.2e-12 45.6 0.0 1.1e-11 44.3 0.0 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Pkinase PF00069.20 EIE76248.1 - 3.9e-61 206.4 0.4 4.5e-61 206.2 0.3 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE76248.1 - 6.2e-20 71.3 0.0 8.7e-20 70.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIE76248.1 - 1.1e-05 25.3 0.0 8.2e-05 22.4 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EIE76248.1 - 0.0041 16.7 0.0 0.0081 15.7 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 EIE76248.1 - 0.058 12.4 0.2 0.11 11.5 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DNA_pol3_delta2 PF13177.1 EIE76249.1 - 4.8e-10 39.3 0.1 6.5e-10 38.9 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 EIE76249.1 - 2.3e-05 24.5 0.5 3.5e-05 24.0 0.1 1.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta PF06144.8 EIE76249.1 - 0.00096 18.7 0.1 0.0014 18.1 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Bac_DnaA PF00308.13 EIE76249.1 - 0.05 13.2 0.6 0.081 12.5 0.4 1.4 1 1 0 1 1 1 0 Bacterial dnaA protein DEAD PF00270.24 EIE76249.1 - 0.052 13.0 0.2 0.09 12.2 0.1 1.3 1 0 0 1 1 1 0 DEAD/DEAH box helicase SNF2_N PF00176.18 EIE76249.1 - 0.082 11.6 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain AAA_22 PF13401.1 EIE76249.1 - 0.11 12.6 0.4 0.18 11.9 0.1 1.5 2 0 0 2 2 2 0 AAA domain Ank_2 PF12796.2 EIE76250.1 - 5.1e-24 84.4 8.6 1.3e-09 38.2 0.1 4.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EIE76250.1 - 5.6e-19 66.9 14.2 0.0098 15.6 0.0 7.4 6 1 1 7 7 7 6 Ankyrin repeat Ank_5 PF13857.1 EIE76250.1 - 2.1e-18 65.9 7.2 0.002 18.2 0.0 7.3 2 1 6 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIE76250.1 - 5.6e-17 60.1 10.9 0.4 11.0 0.1 7.9 8 0 0 8 8 8 6 Ankyrin repeat Ank_4 PF13637.1 EIE76250.1 - 8.9e-16 57.9 7.9 0.063 13.8 0.0 6.5 4 1 1 6 6 6 6 Ankyrin repeats (many copies) Pkip-1 PF06878.6 EIE76250.1 - 0.03 14.1 0.1 6.7 6.5 0.0 2.5 2 0 0 2 2 2 0 Pkip-1 protein Complex1_LYR PF05347.10 EIE76251.1 - 9.2e-12 44.5 2.1 1.4e-11 43.9 1.4 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EIE76251.1 - 3e-09 36.9 1.3 3.9e-09 36.5 0.9 1.1 1 0 0 1 1 1 1 Complex1_LYR-like mIF3 PF14877.1 EIE76251.1 - 0.025 13.9 0.6 0.032 13.5 0.4 1.3 1 0 0 1 1 1 0 Mitochondrial translation initiation factor Cupin_4 PF08007.7 EIE76251.1 - 0.11 11.6 0.1 0.14 11.3 0.1 1.1 1 0 0 1 1 1 0 Cupin superfamily protein Transthyretin PF00576.16 EIE76252.1 - 1.3e-37 128.1 0.0 1.4e-37 127.9 0.0 1.0 1 0 0 1 1 1 1 HIUase/Transthyretin family KIX PF02172.11 EIE76252.1 - 0.0079 16.2 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 KIX domain HTH_23 PF13384.1 EIE76253.1 - 0.00025 20.5 0.3 0.00041 19.9 0.0 1.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.1 EIE76253.1 - 0.049 13.6 0.0 1.2 9.1 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain RHS PF03527.9 EIE76253.1 - 0.092 12.5 0.1 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 RHS protein HTH_Crp_2 PF13545.1 EIE76253.1 - 0.11 12.3 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain DUF3818 PF12825.2 EIE76254.1 - 2.4e-45 154.7 18.3 4.3e-27 94.6 3.3 3.7 2 1 2 4 4 4 3 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 EIE76254.1 - 6.5e-15 54.9 7.1 5.1e-13 48.8 3.9 3.3 2 1 0 2 2 2 1 PX-associated PX PF00787.19 EIE76254.1 - 2.5e-08 33.7 4.4 2.5e-08 33.7 3.1 3.0 3 0 0 3 3 3 1 PX domain zf-H2C2_2 PF13465.1 EIE76256.1 - 6.5e-08 32.4 1.6 6.5e-08 32.4 1.1 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 EIE76256.1 - 2.4e-07 30.7 12.6 3.4e-05 23.9 0.8 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIE76256.1 - 9.7e-06 25.5 11.5 0.0022 18.1 0.5 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EIE76256.1 - 0.0055 16.5 2.7 0.042 13.7 0.1 3.0 3 0 0 3 3 3 1 C2H2-type zinc finger Glyco_hydro_47 PF01532.15 EIE76257.1 - 6.1e-104 348.1 2.1 8.3e-104 347.7 1.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF1713 PF08213.6 EIE76258.1 - 4.9e-15 54.8 18.8 6.4e-15 54.4 13.1 1.2 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) DUF4071 PF13281.1 EIE76258.1 - 0.068 12.0 0.2 0.073 11.9 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4071) Ribosomal_S13 PF00416.17 EIE76259.1 - 3.8e-38 130.2 1.7 4.6e-38 129.9 1.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 EIE76259.1 - 0.0011 17.5 0.0 0.0013 17.4 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) DUF1822 PF08852.6 EIE76259.1 - 0.091 11.5 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1822) adh_short PF00106.20 EIE76260.1 - 3.8e-15 56.1 0.0 5e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIE76260.1 - 6.8e-10 38.8 0.0 8.8e-10 38.5 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EIE76260.1 - 6.5e-07 29.0 0.0 1.1e-06 28.2 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EIE76260.1 - 1.1e-05 25.3 0.1 1.6e-05 24.8 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EIE76260.1 - 2.4e-05 24.4 0.2 6e-05 23.1 0.1 1.7 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EIE76260.1 - 0.0052 15.7 0.0 0.0066 15.4 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 EIE76260.1 - 0.013 14.4 0.1 0.018 13.9 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein MOZART1 PF12554.3 EIE76261.1 - 0.13 11.7 0.5 3.3 7.2 0.1 2.2 1 1 1 2 2 2 0 Mitotic-spindle organizing gamma-tubulin ring associated HHV6-IE PF03753.8 EIE76262.1 - 0.036 11.5 0.0 0.036 11.5 0.0 1.0 1 0 0 1 1 1 0 Human herpesvirus 6 immediate early protein SPRY PF00622.23 EIE76264.1 - 7.1e-20 71.3 0.0 1.5e-19 70.3 0.0 1.5 1 0 0 1 1 1 1 SPRY domain Viral_Beta_CD PF04530.7 EIE76264.1 - 0.071 13.2 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Viral Beta C/D like family PAP_assoc PF03828.14 EIE76265.1 - 1.3e-18 66.7 0.1 1.3e-18 66.7 0.0 2.4 2 0 0 2 2 2 1 Cid1 family poly A polymerase HLH PF00010.21 EIE76266.1 - 1.9e-10 40.2 1.1 4.4e-10 39.1 0.1 2.2 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain Cas_DxTHG PF09455.5 EIE76266.1 - 0.031 13.4 0.2 0.066 12.3 0.2 1.4 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family Blo-t-5 PF11642.3 EIE76266.1 - 0.095 12.4 5.6 0.56 9.9 0.2 2.5 2 0 0 2 2 2 0 Mite allergen Blo t 5 IncA PF04156.9 EIE76268.1 - 0.37 10.3 4.2 0.64 9.5 2.9 1.4 1 0 0 1 1 1 0 IncA protein DUF4045 PF13254.1 EIE76269.1 - 0.41 9.8 2.7 0.44 9.7 1.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) RVT_1 PF00078.22 EIE76272.1 - 4.9e-11 42.3 0.0 7.9e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Osmo_CC PF08946.5 EIE76272.1 - 7.6 6.6 6.8 20 5.3 0.7 2.6 3 0 0 3 3 3 0 Osmosensory transporter coiled coil TPR_11 PF13414.1 EIE76274.1 - 3.8e-14 52.0 4.3 5.8e-12 45.0 0.5 2.7 3 0 0 3 3 3 2 TPR repeat TPR_1 PF00515.23 EIE76274.1 - 2.2e-13 49.1 6.1 2e-05 23.9 0.1 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 EIE76274.1 - 4.1e-09 35.6 8.1 0.0042 16.8 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat DUF3856 PF12968.2 EIE76274.1 - 2.5e-05 24.1 1.2 0.0001 22.1 0.5 2.2 1 1 1 2 2 2 1 Domain of Unknown Function (DUF3856) TPR_16 PF13432.1 EIE76274.1 - 0.00059 20.4 5.1 3.2 8.5 0.2 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat DnaJ PF00226.26 EIE76274.1 - 0.0016 18.0 0.0 0.005 16.5 0.0 1.8 1 0 0 1 1 1 1 DnaJ domain TPR_12 PF13424.1 EIE76274.1 - 0.0069 16.3 6.4 8.4 6.4 2.6 3.3 1 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EIE76274.1 - 0.011 15.4 6.6 0.32 10.8 0.5 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EIE76274.1 - 0.046 13.6 0.2 0.17 11.8 0.2 1.9 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.1 EIE76274.1 - 0.22 12.2 2.3 12 6.8 0.3 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 EIE76274.1 - 4.6 7.2 5.3 39 4.3 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Atrophin-1 PF03154.10 EIE76274.1 - 5.6 4.9 10.5 0.15 10.2 1.8 1.8 2 0 0 2 2 2 0 Atrophin-1 family PH PF00169.24 EIE76275.1 - 2.2e-07 31.0 0.1 1.1e-06 28.7 0.1 2.2 1 0 0 1 1 1 1 PH domain RA PF00788.18 EIE76275.1 - 1.6e-06 28.5 1.6 7.3e-06 26.3 0.0 2.8 3 0 0 3 3 3 1 Ras association (RalGDS/AF-6) domain CBFB_NFYA PF02045.10 EIE76276.1 - 1.1e-30 105.9 6.0 1.7e-30 105.2 4.1 1.3 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B PRCC PF10253.4 EIE76276.1 - 0.026 15.2 2.8 0.033 14.9 1.9 1.0 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting LINES_N PF14694.1 EIE76277.1 - 6.2e-07 29.0 6.5 6.2e-07 29.0 4.5 1.4 2 0 0 2 2 2 1 Lines N-terminus LINES_C PF14695.1 EIE76277.1 - 0.0033 16.6 0.0 0.0085 15.3 0.0 1.7 1 0 0 1 1 1 1 Lines C-terminus JAB PF01398.16 EIE76279.1 - 3.6e-07 29.9 0.1 1.2e-06 28.2 0.0 1.9 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Myb_DNA-binding PF00249.26 EIE76279.1 - 1.7e-06 28.0 2.2 2.9e-06 27.2 0.0 2.6 3 0 0 3 3 3 1 Myb-like DNA-binding domain SAGA-Tad1 PF12767.2 EIE76279.1 - 0.015 14.9 0.1 0.035 13.7 0.1 1.5 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Myb_DNA-bind_6 PF13921.1 EIE76279.1 - 0.029 14.4 0.2 0.16 12.1 0.0 2.3 2 0 0 2 2 2 0 Myb-like DNA-binding domain Sec10 PF07393.6 EIE76280.1 - 1.6e-100 337.3 8.7 8.1e-75 252.4 3.6 2.0 1 1 1 2 2 2 2 Exocyst complex component Sec10 F-box-like PF12937.2 EIE76280.1 - 1.1e-11 44.2 0.2 3.1e-11 42.7 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIE76280.1 - 1.2e-07 31.1 0.2 2.8e-07 30.0 0.2 1.6 1 0 0 1 1 1 1 F-box domain MutS_III PF05192.13 EIE76281.1 - 1.3e-18 67.5 0.0 2e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 MutS domain III MutS_V PF00488.16 EIE76282.1 - 5.7e-49 166.6 0.5 5.6e-47 160.1 0.3 2.0 1 1 0 1 1 1 1 MutS domain V AAA_14 PF13173.1 EIE76282.1 - 0.0029 17.5 0.0 0.0039 17.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EIE76282.1 - 0.021 14.9 0.0 0.029 14.5 0.0 1.3 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.1 EIE76282.1 - 0.029 13.9 0.0 0.055 13.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 EIE76282.1 - 0.12 12.6 0.0 0.18 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EIE76282.1 - 0.14 13.0 0.0 0.2 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.14 EIE76282.1 - 0.14 11.3 0.0 0.31 10.2 0.0 1.5 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain rRNA_proc-arch PF13234.1 EIE76283.1 - 3.5e-93 311.6 2.3 6.2e-93 310.8 1.6 1.4 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.7 EIE76283.1 - 7.7e-63 210.9 0.7 2.3e-62 209.4 0.5 1.9 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 EIE76283.1 - 5.1e-22 78.1 0.0 2.9e-21 75.6 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIE76283.1 - 3.3e-08 33.2 0.0 1.1e-07 31.5 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain T2SE PF00437.15 EIE76283.1 - 0.0044 15.9 0.0 0.028 13.3 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein DNA_ligase_A_N PF04675.9 EIE76283.1 - 0.019 14.7 0.2 0.16 11.7 0.1 2.3 2 0 0 2 2 2 0 DNA ligase N terminus ResIII PF04851.10 EIE76283.1 - 0.12 12.1 0.0 0.12 12.1 0.0 2.8 3 1 0 3 3 3 0 Type III restriction enzyme, res subunit Ribosomal_L33 PF00471.15 EIE76284.1 - 6.6e-11 42.2 0.0 9.2e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L33 Ribosomal_L37ae PF01780.14 EIE76285.1 - 9.3e-41 137.6 10.8 1e-40 137.4 7.5 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.2 EIE76285.1 - 0.00069 19.3 2.2 0.001 18.8 1.5 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain A2L_zn_ribbon PF08792.5 EIE76285.1 - 0.0047 16.3 3.3 0.84 9.1 0.1 2.2 2 0 0 2 2 2 2 A2L zinc ribbon domain zf-FCS PF06467.9 EIE76285.1 - 0.027 14.0 2.2 0.75 9.4 0.1 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-H2C2_2 PF13465.1 EIE76285.1 - 0.08 13.2 1.4 2.5 8.5 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger double domain zf-BED PF02892.10 EIE76285.1 - 0.1 12.3 5.5 0.12 12.1 0.4 2.3 1 1 1 2 2 2 0 BED zinc finger Zn-ribbon_8 PF09723.5 EIE76285.1 - 0.17 11.8 1.7 0.9 9.5 0.1 2.2 2 0 0 2 2 2 0 Zinc ribbon domain Elf1 PF05129.8 EIE76285.1 - 0.27 10.9 2.7 0.5 10.0 1.9 1.5 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like zf-C2H2 PF00096.21 EIE76285.1 - 1.8 9.0 4.1 18 5.8 0.3 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type Cullin_binding PF03556.10 EIE76286.1 - 4.4e-34 117.1 1.8 8.9e-34 116.1 0.1 1.9 2 0 0 2 2 2 1 Cullin binding UBA_4 PF14555.1 EIE76286.1 - 4.3e-12 45.3 0.1 1.6e-11 43.5 0.0 2.1 2 0 0 2 2 2 1 UBA-like domain UBA PF00627.26 EIE76286.1 - 0.00031 20.4 0.0 0.001 18.8 0.0 2.0 2 0 0 2 2 2 1 UBA/TS-N domain Tmemb_cc2 PF10267.4 EIE76286.1 - 0.015 13.8 0.1 0.026 13.1 0.0 1.3 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein PipA PF07108.6 EIE76286.1 - 0.055 12.8 0.0 0.076 12.3 0.0 1.4 1 0 0 1 1 1 0 PipA protein NUDIX PF00293.23 EIE76289.1 - 3.4e-17 62.3 0.0 5.2e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain BON PF04972.12 EIE76289.1 - 0.039 13.7 0.1 0.076 12.7 0.1 1.5 1 0 0 1 1 1 0 BON domain MIP-T3 PF10243.4 EIE76289.1 - 2.1 6.7 82.1 3.4 6.0 56.9 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Homeobox_KN PF05920.6 EIE76290.1 - 6.6e-09 35.3 0.4 6.6e-09 35.3 0.3 2.3 2 0 0 2 2 2 1 Homeobox KN domain Homeobox PF00046.24 EIE76290.1 - 0.001 18.6 0.1 0.0038 16.8 0.1 2.0 2 0 0 2 2 2 1 Homeobox domain FAM86 PF14904.1 EIE76290.1 - 0.07 12.8 0.1 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function IFT46_B_C PF12317.3 EIE76291.1 - 1.7 7.9 5.9 2.6 7.3 1.0 2.0 1 1 1 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal HEAT_2 PF13646.1 EIE76292.1 - 8.6e-09 35.5 0.0 0.00017 21.7 0.0 2.9 1 1 2 3 3 3 2 HEAT repeats HEAT PF02985.17 EIE76292.1 - 0.00012 21.8 0.1 0.22 11.6 0.0 3.0 3 1 1 4 4 4 2 HEAT repeat HEAT_EZ PF13513.1 EIE76292.1 - 0.00013 22.3 0.0 0.0013 19.1 0.0 2.3 1 1 1 2 2 2 2 HEAT-like repeat Arm PF00514.18 EIE76292.1 - 0.00029 20.5 0.0 0.075 12.8 0.0 2.8 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.15 EIE76292.1 - 0.0094 14.3 0.2 0.22 9.8 0.1 2.4 1 1 1 2 2 2 1 Adaptin N terminal region Chordopox_G2 PF05796.7 EIE76292.1 - 0.016 14.3 0.2 0.032 13.3 0.2 1.6 1 1 0 1 1 1 0 Chordopoxvirus protein G2 COMPASS-Shg1 PF05205.7 EIE76292.1 - 0.018 15.3 0.4 0.034 14.4 0.3 1.5 1 0 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component shg1 Dynein_light PF01221.13 EIE76293.1 - 1e-43 147.2 2.2 1.1e-43 147.1 1.5 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Lum_binding PF00677.12 EIE76293.1 - 0.14 12.0 0.3 0.2 11.5 0.2 1.2 1 0 0 1 1 1 0 Lumazine binding domain Mem_trans PF03547.13 EIE76294.1 - 8.1e-41 139.5 10.2 1.1e-40 139.1 7.1 1.2 1 0 0 1 1 1 1 Membrane transport protein FUSC PF04632.7 EIE76294.1 - 8.7 4.6 10.2 14 3.9 7.1 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family HSP70 PF00012.15 EIE76295.1 - 6.5e-263 873.1 13.6 6.5e-263 873.1 9.4 1.4 2 0 0 2 2 2 1 Hsp70 protein PNP_UDP_1 PF01048.15 EIE76295.1 - 4.5e-45 153.4 0.3 8.3e-45 152.5 0.2 1.5 1 0 0 1 1 1 1 Phosphorylase superfamily MreB_Mbl PF06723.8 EIE76295.1 - 1.3e-13 50.2 5.0 7e-12 44.5 1.0 2.7 2 1 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 EIE76295.1 - 0.002 17.7 0.0 0.0042 16.7 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 EIE76295.1 - 0.0023 17.7 6.9 1.2 9.0 0.0 4.6 3 2 0 3 3 3 2 Cell division protein FtsA Phage_GP20 PF06810.6 EIE76295.1 - 0.22 10.9 11.9 0.015 14.7 4.3 2.0 2 0 0 2 2 2 0 Phage minor structural protein GP20 ELMO_CED12 PF04727.8 EIE76296.1 - 1.5e-11 44.1 1.1 2.6e-10 40.1 0.0 2.5 2 1 1 3 3 3 2 ELMO/CED-12 family PIF1 PF05970.9 EIE76297.1 - 1.9e-24 86.3 0.9 8.1e-22 77.6 0.0 3.0 2 1 1 3 3 3 1 PIF1-like helicase AAA_30 PF13604.1 EIE76297.1 - 1.7e-14 53.8 0.0 2.5e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 EIE76297.1 - 6.5e-06 25.8 0.0 0.035 13.6 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.1 EIE76297.1 - 5.9e-05 22.9 0.0 0.00034 20.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 EIE76297.1 - 0.00058 20.1 0.0 0.0017 18.6 0.0 2.0 1 1 0 1 1 1 1 ABC transporter PhoH PF02562.11 EIE76297.1 - 0.00074 18.7 0.0 0.0019 17.5 0.0 1.6 1 0 0 1 1 1 1 PhoH-like protein AAA_19 PF13245.1 EIE76297.1 - 0.0011 18.7 0.0 0.0032 17.2 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 EIE76297.1 - 0.0061 16.6 0.0 0.023 14.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EIE76297.1 - 0.026 13.7 0.0 0.082 12.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_17 PF13207.1 EIE76297.1 - 0.048 14.4 0.0 0.12 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 EIE76297.1 - 0.064 12.0 0.0 0.11 11.2 0.0 1.3 1 0 0 1 1 1 0 ArgK protein AAA_16 PF13191.1 EIE76297.1 - 0.095 12.6 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.7 EIE76297.1 - 0.11 12.1 0.1 0.9 9.1 0.0 2.4 3 0 0 3 3 3 0 NACHT domain AAA_12 PF13087.1 EIE76298.1 - 2.8e-14 52.9 0.1 6.1e-14 51.8 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EIE76298.1 - 6.1e-09 35.8 0.0 5.5e-08 32.6 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EIE76298.1 - 0.00016 21.3 0.1 0.00035 20.2 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain PhoH PF02562.11 EIE76298.1 - 0.001 18.3 0.1 0.0027 16.9 0.0 1.6 1 0 0 1 1 1 1 PhoH-like protein AAA_30 PF13604.1 EIE76298.1 - 0.0013 18.3 0.1 0.0031 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EIE76298.1 - 0.012 15.3 0.1 2.5 7.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EIE76298.1 - 0.012 14.9 0.0 0.028 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EIE76298.1 - 0.015 15.4 0.1 0.085 12.9 0.0 2.3 3 0 0 3 3 1 0 AAA domain AAA_17 PF13207.1 EIE76298.1 - 0.02 15.7 0.0 0.078 13.7 0.0 2.1 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EIE76298.1 - 0.078 12.3 0.0 0.2 11.0 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein NACHT PF05729.7 EIE76298.1 - 0.086 12.4 0.0 0.24 11.0 0.0 1.8 1 0 0 1 1 1 0 NACHT domain Helicase_RecD PF05127.9 EIE76298.1 - 0.14 11.7 0.1 4.1 6.9 0.0 2.7 2 0 0 2 2 2 0 Helicase AAA PF00004.24 EIE76298.1 - 0.29 11.3 0.5 1.3 9.2 0.0 2.4 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EIE76298.1 - 0.37 11.1 3.2 1 9.6 0.0 3.3 4 0 0 4 4 4 0 AAA domain DDE_3 PF13358.1 EIE76300.1 - 0.001 18.8 0.2 0.0027 17.4 0.1 1.9 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE76300.1 - 0.017 15.2 0.1 0.29 11.2 0.0 2.8 2 0 0 2 2 2 0 Transposase Vsr PF03852.10 EIE76300.1 - 0.044 13.4 0.0 0.14 11.7 0.0 1.9 1 0 0 1 1 1 0 DNA mismatch endonuclease Vsr Acyl_CoA_thio PF02551.10 EIE76301.1 - 0.099 12.2 0.1 0.14 11.7 0.1 1.2 1 0 0 1 1 1 0 Acyl-CoA thioesterase AdoHcyase_NAD PF00670.16 EIE76304.1 - 6.7e-88 292.6 3.4 8.4e-88 292.3 2.3 1.1 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AdoHcyase PF05221.12 EIE76304.1 - 2.5e-47 161.0 0.0 2.8e-47 160.9 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase 2-Hacid_dh_C PF02826.14 EIE76304.1 - 1e-09 37.7 0.7 1.5e-09 37.2 0.1 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 EIE76304.1 - 5.8e-06 25.7 0.2 7.9e-06 25.3 0.2 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 EIE76304.1 - 0.00077 19.4 0.1 0.0014 18.5 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain ELFV_dehydrog PF00208.16 EIE76304.1 - 0.057 12.9 0.2 0.074 12.6 0.1 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Urocanase PF01175.13 EIE76304.1 - 0.086 10.8 0.2 0.12 10.3 0.1 1.1 1 0 0 1 1 1 0 Urocanase Myc_N PF01056.13 EIE76306.1 - 0.37 9.8 3.3 0.47 9.5 2.3 1.1 1 0 0 1 1 1 0 Myc amino-terminal region CENP-F_leu_zip PF10473.4 EIE76308.1 - 0.0023 17.7 14.9 0.0023 17.7 10.3 15.1 4 3 8 14 14 14 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TBPIP PF07106.8 EIE76308.1 - 0.0038 16.7 10.1 0.0038 16.7 7.0 16.7 4 3 13 17 17 17 3 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Mnd1 PF03962.10 EIE76308.1 - 0.0051 16.4 10.2 0.0051 16.4 7.1 14.3 3 2 12 15 15 15 3 Mnd1 family PT PF04886.7 EIE76308.1 - 1.9 7.8 12.5 0.058 12.7 3.6 2.1 2 0 0 2 2 2 0 PT repeat DDE_3 PF13358.1 EIE76309.1 - 0.00014 21.5 0.1 0.00019 21.1 0.1 1.3 1 1 0 1 1 1 1 DDE superfamily endonuclease Phage_C PF12025.3 EIE76309.1 - 0.12 12.3 0.1 0.2 11.6 0.1 1.4 1 0 0 1 1 1 0 Phage protein C DUF1192 PF06698.6 EIE76310.1 - 0.001 18.8 0.1 0.0026 17.5 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1192) DivIC PF04977.10 EIE76310.1 - 0.016 14.6 3.1 0.03 13.8 2.1 1.4 1 0 0 1 1 1 0 Septum formation initiator TMF_TATA_bd PF12325.3 EIE76310.1 - 0.046 13.4 0.4 0.075 12.7 0.2 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 EIE76310.1 - 0.15 11.8 2.1 0.29 10.9 1.5 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding SlyX PF04102.7 EIE76310.1 - 0.32 11.3 2.6 0.3 11.4 0.8 1.6 2 0 0 2 2 2 0 SlyX RHD3 PF05879.7 EIE76311.1 - 1.4e-141 472.9 21.9 5.5e-128 427.9 9.7 2.0 1 1 1 2 2 2 2 Root hair defective 3 GTP-binding protein (RHD3) NAAA-beta PF15508.1 EIE76311.1 - 0.0049 17.1 2.9 0.063 13.6 0.1 3.5 3 1 2 5 5 5 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Synaptobrevin PF00957.16 EIE76311.1 - 0.014 14.9 1.4 2 8.0 0.1 2.8 2 0 0 2 2 2 0 Synaptobrevin RmlD_sub_bind PF04321.12 EIE76312.1 - 1.8e-60 204.3 0.0 2.2e-60 204.0 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 EIE76312.1 - 2.7e-17 62.9 0.1 1.5e-16 60.5 0.0 2.0 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EIE76312.1 - 5.7e-09 35.2 0.0 1.1e-08 34.3 0.0 1.5 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 EIE76312.1 - 4.7e-06 25.7 0.1 3e-05 23.0 0.0 2.2 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EIE76312.1 - 2.2e-05 24.5 0.1 3.2e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding CN_hydrolase PF00795.17 EIE76313.1 - 4.1e-08 32.8 0.0 1.3e-07 31.1 0.0 1.8 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase DUF2605 PF10792.4 EIE76313.1 - 0.013 15.1 0.1 0.029 14.0 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2605) SPC12 PF06645.8 EIE76313.1 - 0.04 13.7 1.3 10 6.0 0.0 2.7 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) SPK PF04435.13 EIE76313.1 - 0.17 11.8 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF545) Ank_2 PF12796.2 EIE76314.1 - 3.4e-08 33.6 0.0 4.3e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EIE76314.1 - 4.2e-07 30.2 0.0 8.4e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 EIE76314.1 - 3.5e-06 26.5 0.0 0.00019 21.0 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.1 EIE76314.1 - 5.2e-06 26.2 0.0 0.011 15.8 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 EIE76314.1 - 3.4e-05 23.9 0.0 0.0051 17.0 0.0 2.2 1 1 1 2 2 2 1 Ankyrin repeats (many copies) CtaG_Cox11 PF04442.9 EIE76314.1 - 0.13 12.0 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein CtaG/Cox11 WD40 PF00400.27 EIE76315.1 - 7.1e-07 28.8 0.0 0.0084 15.9 0.0 2.8 2 0 0 2 2 2 2 WD domain, G-beta repeat Ycf1 PF05758.7 EIE76315.1 - 0.11 10.1 0.3 0.093 10.4 0.2 1.1 1 0 0 1 1 1 0 Ycf1 BUD22 PF09073.5 EIE76315.1 - 0.36 9.8 11.9 0.54 9.2 8.2 1.3 1 0 0 1 1 1 0 BUD22 Daxx PF03344.10 EIE76315.1 - 0.67 8.3 19.4 1.1 7.6 13.5 1.3 1 0 0 1 1 1 0 Daxx Family Pox_Ag35 PF03286.9 EIE76315.1 - 1.2 8.6 11.6 2.1 7.8 8.0 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Prothymosin PF03247.9 EIE76315.1 - 9.8 6.3 31.9 19 5.4 22.1 1.4 1 0 0 1 1 1 0 Prothymosin/parathymosin family DDE_3 PF13358.1 EIE76317.1 - 8.1e-06 25.6 0.0 1e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Nepo_coat PF03391.10 EIE76317.1 - 0.11 11.7 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 Nepovirus coat protein, central domain EI24 PF07264.6 EIE76318.1 - 0.00095 18.6 5.1 0.0014 18.1 3.5 1.1 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) SUR7 PF06687.7 EIE76318.1 - 0.0091 15.5 10.6 0.023 14.2 7.0 1.8 1 1 1 2 2 2 1 SUR7/PalI family MARVEL PF01284.18 EIE76318.1 - 0.05 13.4 8.4 0.11 12.2 2.8 2.4 1 1 1 2 2 2 0 Membrane-associating domain DUF4118 PF13493.1 EIE76318.1 - 1.1 9.5 6.3 0.29 11.3 1.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4118) DUF3671 PF12420.3 EIE76318.1 - 1.2 9.1 3.5 0.69 9.9 1.1 1.6 2 0 0 2 2 2 0 Protein of unknown function Claudin_2 PF13903.1 EIE76318.1 - 2.4 7.8 9.0 8.3 6.0 6.4 1.8 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Ctr PF04145.10 EIE76319.1 - 1.8e-40 138.2 6.3 2.1e-40 138.0 4.4 1.0 1 0 0 1 1 1 1 Ctr copper transporter family Nucleoside_tran PF01733.13 EIE76319.1 - 0.0041 16.3 0.1 0.0053 15.9 0.0 1.1 1 0 0 1 1 1 1 Nucleoside transporter Fes1 PF08609.5 EIE76319.1 - 0.054 13.9 1.1 1.6 9.2 0.7 2.1 1 1 0 1 1 1 0 Nucleotide exchange factor Fes1 DUF4131 PF13567.1 EIE76319.1 - 0.12 11.7 0.1 0.12 11.7 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Abi PF02517.11 EIE76319.1 - 0.17 12.0 6.4 1 9.5 0.3 2.1 2 0 0 2 2 2 0 CAAX protease self-immunity 2TM PF13239.1 EIE76319.1 - 7.2 6.7 9.9 6.9 6.8 1.5 2.2 2 0 0 2 2 2 0 2TM domain PIG-P PF08510.7 EIE76319.1 - 9.8 5.8 10.1 0.65 9.6 0.3 2.2 1 1 1 2 2 2 0 PIG-P DUF2296 PF10058.4 EIE76320.1 - 9e-14 50.9 0.0 1.6e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) Mononeg_mRNAcap PF14318.1 EIE76320.1 - 0.097 11.6 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 Mononegavirales mRNA-capping region V Tim54 PF11711.3 EIE76320.1 - 0.19 10.2 5.6 0.24 9.9 3.9 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 ATP11 PF06644.6 EIE76320.1 - 0.8 9.1 7.1 1.1 8.7 4.9 1.1 1 0 0 1 1 1 0 ATP11 protein Pex14_N PF04695.8 EIE76320.1 - 3.5 7.6 8.7 9 6.3 6.0 1.7 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3824 PF12868.2 EIE76320.1 - 8.4 7.3 16.8 12 6.8 11.7 1.2 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) zf-U1 PF06220.7 EIE76321.1 - 6.4e-06 25.6 10.1 0.001 18.5 7.0 2.2 1 1 0 1 1 1 1 U1 zinc finger PIF1 PF05970.9 EIE76322.1 - 1.2e-13 50.7 0.1 1.5e-13 50.4 0.1 1.2 1 0 0 1 1 1 1 PIF1-like helicase Herpes_Helicase PF02689.9 EIE76322.1 - 7.1e-07 27.3 0.0 8.4e-07 27.1 0.0 1.0 1 0 0 1 1 1 1 Helicase DUF3251 PF11622.3 EIE76322.1 - 0.0027 17.1 0.0 0.0061 15.9 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3251) UvrD_C_2 PF13538.1 EIE76322.1 - 0.003 17.6 0.0 0.0051 16.9 0.0 1.5 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain SpoIID PF08486.5 EIE76323.1 - 0.026 14.7 0.0 0.14 12.4 0.0 2.0 1 1 0 1 1 1 0 Stage II sporulation protein DUF573 PF04504.9 EIE76323.1 - 0.048 13.9 1.6 0.73 10.1 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function, DUF573 CAF1 PF04857.15 EIE76323.1 - 0.051 12.9 0.1 0.062 12.6 0.1 1.2 1 0 0 1 1 1 0 CAF1 family ribonuclease Fib_alpha PF08702.5 EIE76323.1 - 0.092 12.8 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family TetR_C_6 PF13977.1 EIE76324.1 - 0.1 12.5 0.1 0.1 12.5 0.1 1.0 1 0 0 1 1 1 0 Bacterial transcriptional repressor RVT_1 PF00078.22 EIE76325.1 - 8.5e-24 84.0 0.1 1.9e-23 82.9 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.1 EIE76325.1 - 7.2e-06 26.2 1.1 2e-05 24.7 0.8 1.8 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase COX15-CtaA PF02628.10 EIE76326.1 - 7.8e-77 258.1 0.9 1.1e-75 254.3 0.7 2.0 1 1 0 1 1 1 1 Cytochrome oxidase assembly protein Na_Ca_ex PF01699.19 EIE76326.1 - 0.027 14.0 1.3 0.074 12.6 0.1 2.3 2 0 0 2 2 2 0 Sodium/calcium exchanger protein HEAT_2 PF13646.1 EIE76327.1 - 5.3e-27 93.9 1.2 2.3e-08 34.1 0.1 7.7 4 2 4 8 8 8 6 HEAT repeats HEAT PF02985.17 EIE76327.1 - 6e-24 81.9 11.0 2.1e-05 24.2 0.1 11.3 12 0 0 12 12 12 4 HEAT repeat HEAT_EZ PF13513.1 EIE76327.1 - 1.7e-22 79.2 5.8 3.5e-07 30.5 0.0 11.2 9 1 6 15 15 14 5 HEAT-like repeat CLASP_N PF12348.3 EIE76327.1 - 8e-13 48.2 0.1 0.0036 16.6 0.0 7.2 5 3 3 8 8 8 3 CLASP N terminal Vac14_Fab1_bd PF12755.2 EIE76327.1 - 6.2e-12 45.7 0.9 0.00084 19.6 0.0 8.0 6 1 3 10 10 10 4 Vacuolar 14 Fab1-binding region IBN_N PF03810.14 EIE76327.1 - 1.1e-07 31.6 2.0 3e-07 30.2 0.4 2.7 3 0 0 3 3 1 1 Importin-beta N-terminal domain MMS19_C PF12460.3 EIE76327.1 - 4.1e-06 25.8 0.5 0.023 13.4 0.0 4.6 3 1 3 6 6 6 3 RNAPII transcription regulator C-terminal DUF2454 PF10521.4 EIE76327.1 - 4.5e-05 22.6 1.2 1.4 7.8 0.0 5.3 4 2 2 6 6 6 1 Protein of unknown function (DUF2454) Ipi1_N PF12333.3 EIE76327.1 - 0.00062 19.6 0.1 0.3 11.0 0.0 4.5 4 1 1 5 5 5 2 Rix1 complex component involved in 60S ribosome maturation ParcG PF10274.4 EIE76327.1 - 0.0029 17.5 0.1 0.049 13.5 0.0 3.0 3 1 1 4 4 4 1 Parkin co-regulated protein DUF3385 PF11865.3 EIE76327.1 - 0.012 15.4 0.4 17 5.3 0.2 4.6 2 2 1 3 3 3 0 Domain of unknown function (DUF3385) Nucleopor_Nup85 PF07575.8 EIE76327.1 - 0.031 12.5 1.6 0.31 9.2 0.1 2.7 3 1 1 4 4 4 0 Nup85 Nucleoporin IFRD PF05004.8 EIE76327.1 - 0.034 13.2 0.0 0.86 8.6 0.0 2.6 2 0 0 2 2 2 0 Interferon-related developmental regulator (IFRD) Katanin_con80 PF13925.1 EIE76327.1 - 0.035 13.8 0.6 5.6 6.6 0.1 3.1 3 0 0 3 3 3 0 con80 domain of Katanin Arm PF00514.18 EIE76327.1 - 0.61 9.9 15.0 14 5.7 0.0 7.3 8 1 1 9 9 8 0 Armadillo/beta-catenin-like repeat Ribosomal_L32e PF01655.13 EIE76328.1 - 2.3e-47 159.5 1.5 2.8e-47 159.3 1.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 Ribosomal_S6 PF01250.12 EIE76330.1 - 1.4e-13 50.5 0.0 1.6e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 DUF1149 PF06619.6 EIE76331.1 - 0.036 13.9 0.7 0.19 11.6 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1149) Gar1 PF04410.9 EIE76332.1 - 7.5e-44 148.9 0.4 7.5e-44 148.9 0.2 1.7 1 1 1 2 2 2 1 Gar1/Naf1 RNA binding region DUF3997 PF13162.1 EIE76332.1 - 0.11 12.3 0.1 0.15 11.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3997) SpoIIE PF07228.7 EIE76334.1 - 5.8e-11 42.4 0.0 8.8e-11 41.8 0.0 1.4 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 EIE76334.1 - 1.2e-10 41.2 0.0 0.00023 20.6 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 EIE76334.1 - 9.3e-10 38.2 0.0 1.2e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C zf-C2H2_4 PF13894.1 EIE76337.1 - 0.0055 16.9 7.0 0.11 12.8 0.1 3.0 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EIE76337.1 - 0.014 15.5 3.4 0.38 10.8 2.0 2.6 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.1 EIE76337.1 - 0.026 14.8 1.6 0.94 9.8 0.2 3.1 2 0 0 2 2 2 0 Zinc-finger double domain Thioredoxin_2 PF13098.1 EIE76337.1 - 0.028 14.5 0.7 0.16 12.1 0.5 2.3 1 1 0 1 1 1 0 Thioredoxin-like domain zf-Di19 PF05605.7 EIE76337.1 - 0.19 11.9 3.6 9.4 6.4 0.8 2.7 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 EIE76337.1 - 1.1 9.7 10.4 1.1 9.7 0.1 3.2 3 0 0 3 3 3 0 Zinc finger, C2H2 type UDPG_MGDP_dh_C PF03720.10 EIE76338.1 - 4.8e-35 119.9 0.7 1.4e-34 118.4 0.2 1.9 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.14 EIE76338.1 - 1.4e-31 108.5 0.0 3.7e-31 107.2 0.0 1.7 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_N PF03721.9 EIE76338.1 - 3.3e-25 88.5 0.2 1.6e-24 86.3 0.0 2.0 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AAA-ATPase_like PF09820.4 EIE76338.1 - 0.0014 17.8 0.6 0.0023 17.1 0.4 1.2 1 0 0 1 1 1 1 Predicted AAA-ATPase NAD_binding_2 PF03446.10 EIE76338.1 - 0.1 12.4 0.2 8.6 6.1 0.0 2.5 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase MMR_HSR1 PF01926.18 EIE76338.1 - 0.1 12.5 0.1 0.22 11.4 0.1 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF4608 PF15381.1 EIE76338.1 - 0.19 11.9 0.9 0.39 10.8 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4608) ACBP PF00887.14 EIE76339.1 - 2.4e-26 91.1 0.0 4e-26 90.5 0.0 1.3 1 0 0 1 1 1 1 Acyl CoA binding protein Ank_4 PF13637.1 EIE76339.1 - 8e-18 64.4 0.3 3.7e-10 40.0 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EIE76339.1 - 4.6e-13 49.3 0.1 7.8e-13 48.5 0.1 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EIE76339.1 - 6.5e-13 48.4 0.0 1.2e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 EIE76339.1 - 1e-11 43.9 0.3 4.1e-09 35.7 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.1 EIE76339.1 - 1.3e-09 37.3 0.2 5.8e-08 32.2 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat WD40 PF00400.27 EIE76340.1 - 7.6e-29 98.5 1.2 7e-06 25.7 0.0 7.2 8 0 0 8 8 8 5 WD domain, G-beta repeat BBS2_Mid PF14783.1 EIE76340.1 - 0.00022 20.9 0.0 1.3 8.7 0.0 4.6 6 0 0 6 6 6 1 Ciliary BBSome complex subunit 2, middle region Nucleoporin_N PF08801.6 EIE76340.1 - 0.0029 16.3 0.1 4.5 5.9 0.0 3.2 2 2 1 3 3 3 2 Nup133 N terminal like Host_attach PF10116.4 EIE76340.1 - 0.032 14.4 0.2 0.1 12.8 0.1 1.9 2 0 0 2 2 2 0 Protein required for attachment to host cells MULE PF10551.4 EIE76341.1 - 3.2e-10 40.0 0.1 7.5e-10 38.8 0.1 1.6 1 0 0 1 1 1 1 MULE transposase domain DUF4159 PF13709.1 EIE76341.1 - 0.02 14.0 0.0 0.051 12.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4159) ERGIC_N PF13850.1 EIE76341.1 - 0.055 13.4 0.1 0.36 10.8 0.0 2.2 2 0 0 2 2 2 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) SWIM PF04434.12 EIE76341.1 - 0.95 9.0 5.8 0.2 11.1 1.4 1.8 2 0 0 2 2 2 0 SWIM zinc finger Colicin_C PF12106.3 EIE76342.1 - 0.24 11.0 2.5 0.51 9.9 1.7 1.6 1 0 0 1 1 1 0 Colicin C terminal ribonuclease domain Peptidase_A21 PF03566.8 EIE76343.1 - 0.0078 14.3 0.0 0.0091 14.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family A21 THOC7 PF05615.8 EIE76344.1 - 9.5e-11 42.1 5.8 9.5e-11 42.1 4.0 2.5 1 1 1 2 2 2 1 Tho complex subunit 7 Mod_r PF07200.8 EIE76344.1 - 0.015 15.1 5.6 0.015 15.1 3.9 2.0 3 1 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein DUF1192 PF06698.6 EIE76344.1 - 0.035 13.9 2.6 0.1 12.4 1.8 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) TCO89 PF10452.4 EIE76344.1 - 0.3 9.9 11.5 0.38 9.5 8.0 1.1 1 0 0 1 1 1 0 TORC1 subunit TCO89 FDF PF09532.5 EIE76344.1 - 0.39 11.2 7.3 1 9.8 5.0 1.7 1 0 0 1 1 1 0 FDF domain DUF2422 PF10337.4 EIE76344.1 - 1.6 7.3 5.6 2.1 7.0 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) Clp1 PF06807.9 EIE76345.1 - 2.8e-31 108.8 0.0 3.7e-30 105.1 0.0 2.5 2 1 0 2 2 2 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 EIE76345.1 - 1.1e-16 60.8 0.0 1.8e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 EIE76345.1 - 0.0061 17.3 0.1 0.022 15.5 0.1 1.9 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.4 EIE76345.1 - 0.0079 15.6 0.0 0.017 14.5 0.0 1.6 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA PF00004.24 EIE76345.1 - 0.024 14.8 0.1 0.054 13.6 0.0 1.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.12 EIE76345.1 - 0.039 13.4 0.0 0.062 12.8 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_14 PF13173.1 EIE76345.1 - 0.04 13.8 0.0 0.085 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 EIE76345.1 - 0.04 13.8 0.3 0.28 11.1 0.1 2.4 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_16 PF13191.1 EIE76345.1 - 0.06 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain SRP54 PF00448.17 EIE76345.1 - 0.079 12.3 0.0 0.33 10.3 0.0 1.9 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_35 PF14516.1 EIE76345.1 - 0.096 11.2 0.0 0.15 10.6 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain Longin PF13774.1 EIE76346.1 - 4.4e-17 61.4 0.0 9e-17 60.4 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 EIE76346.1 - 1.6e-15 56.4 0.6 3.4e-15 55.4 0.4 1.5 1 0 0 1 1 1 1 Synaptobrevin EF_TS PF00889.14 EIE76346.1 - 0.0039 16.5 1.5 0.0058 15.9 0.9 1.4 1 1 0 1 1 1 1 Elongation factor TS Herpes_teg_N PF04843.7 EIE76346.1 - 0.1 12.0 0.7 0.27 10.6 0.0 2.0 3 0 0 3 3 3 0 Herpesvirus tegument protein, N-terminal conserved region PACT_coil_coil PF10495.4 EIE76347.1 - 0.038 13.9 0.9 1.2 9.1 0.0 2.1 1 1 1 2 2 2 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein DUF2117 PF09890.4 EIE76347.1 - 0.043 12.9 0.4 0.053 12.7 0.3 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2117) ADPrib_exo_Tox PF03496.9 EIE76347.1 - 0.08 12.1 0.1 0.082 12.1 0.1 1.1 1 0 0 1 1 1 0 ADP-ribosyltransferase exoenzyme U-box PF04564.10 EIE76347.1 - 0.091 12.7 1.5 0.15 12.0 1.0 1.4 1 0 0 1 1 1 0 U-box domain F-box-like PF12937.2 EIE76348.1 - 5.9e-09 35.5 2.0 8.2e-09 35.0 0.5 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EIE76348.1 - 0.035 13.7 0.0 0.1 12.2 0.0 1.8 1 0 0 1 1 1 0 F-box domain AAA_23 PF13476.1 EIE76348.1 - 0.06 13.6 19.8 0.092 13.0 13.7 1.3 1 0 0 1 1 1 0 AAA domain GAGA_bind PF06217.7 EIE76348.1 - 0.31 10.9 3.1 0.42 10.5 2.2 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Hid1 PF12722.2 EIE76348.1 - 1.9 6.0 13.4 2.4 5.7 9.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein NT-C2 PF10358.4 EIE76349.1 - 1.4e-13 50.5 0.2 1.6e-13 50.3 0.1 1.0 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins XPA_C PF05181.7 EIE76349.1 - 0.057 13.0 0.3 3.7 7.2 0.0 2.1 2 0 0 2 2 2 0 XPA protein C-terminus MFS_1 PF07690.11 EIE76350.1 - 1.8e-39 135.4 24.1 2.5e-39 134.9 16.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1616 PF07760.6 EIE76350.1 - 0.0097 15.0 4.2 0.0099 15.0 2.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1616) Claudin_2 PF13903.1 EIE76351.1 - 1.7e-05 24.6 5.6 0.00018 21.2 0.1 2.2 1 1 1 2 2 2 2 PMP-22/EMP/MP20/Claudin tight junction DUF2232 PF09991.4 EIE76351.1 - 0.0082 15.1 1.7 0.0082 15.1 1.2 1.8 1 1 1 2 2 2 1 Predicted membrane protein (DUF2232) SUR7 PF06687.7 EIE76351.1 - 0.026 14.0 8.3 0.064 12.8 5.8 1.5 1 1 0 1 1 1 0 SUR7/PalI family Sugar_transport PF06800.7 EIE76351.1 - 0.083 11.9 0.2 0.083 11.9 0.1 1.5 2 0 0 2 2 2 0 Sugar transport protein DUF4064 PF13273.1 EIE76351.1 - 0.57 10.3 6.8 5.8 7.0 1.2 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF4064) UBN2_2 PF14227.1 EIE76352.1 - 0.068 12.7 0.6 0.16 11.5 0.0 1.9 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EIE76352.1 - 0.12 12.1 0.1 0.55 10.0 0.1 2.1 1 1 1 2 2 2 0 gag-polypeptide of LTR copia-type TPT PF03151.11 EIE76356.1 - 1.6e-16 60.3 17.5 1.5e-15 57.2 3.2 2.1 2 0 0 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.6 EIE76356.1 - 4.8e-07 28.9 19.6 7.2e-07 28.4 13.6 1.3 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EIE76356.1 - 1.8e-06 28.0 6.6 1.8e-06 28.0 4.6 3.0 1 1 2 3 3 3 1 EamA-like transporter family Nuc_sug_transp PF04142.10 EIE76356.1 - 0.0015 17.6 6.5 0.002 17.2 4.5 1.5 1 1 0 1 1 1 1 Nucleotide-sugar transporter EmrE PF13536.1 EIE76356.1 - 0.8 9.9 13.6 0.037 14.2 2.7 2.9 1 1 1 2 2 2 0 Multidrug resistance efflux transporter Pkinase PF00069.20 EIE76358.1 - 6.8e-14 51.6 0.3 7.9e-14 51.4 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE76358.1 - 6.7e-06 25.3 0.3 7.6e-06 25.1 0.2 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3284 PF11687.3 EIE76358.1 - 0.031 13.9 0.5 0.041 13.5 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3284) GTP_EFTU PF00009.22 EIE76359.1 - 1.5e-45 154.9 0.0 2.4e-45 154.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EIE76359.1 - 8.7e-17 61.1 0.3 2.2e-16 59.8 0.1 1.8 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EIE76359.1 - 1.5e-06 28.2 0.4 1.4e-05 25.0 0.1 2.6 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 EIE76359.1 - 4.3e-05 23.0 0.2 8.9e-05 22.0 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 EIE76359.1 - 0.00011 22.0 0.0 0.00035 20.5 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 EIE76359.1 - 0.013 14.1 0.1 0.043 12.4 0.2 1.6 2 0 0 2 2 2 0 G-protein alpha subunit HBS1_N PF08938.5 EIE76360.1 - 3e-12 46.4 3.9 3.5e-12 46.2 2.4 1.3 1 1 0 1 1 1 1 HBS1 N-terminus RRP14 PF15459.1 EIE76360.1 - 3.7 7.6 11.1 0.27 11.3 4.3 1.6 2 0 0 2 2 2 0 60S ribosome biogenesis protein Rrp14 DUF4514 PF14986.1 EIE76361.1 - 3.4 7.5 6.2 1.2 8.9 1.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4514) RAMP4 PF06624.7 EIE76364.1 - 2.8e-05 23.5 0.0 3.7e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 MarC PF01914.12 EIE76364.1 - 0.061 12.4 0.1 0.065 12.3 0.1 1.1 1 0 0 1 1 1 0 MarC family integral membrane protein DUF3899 PF13038.1 EIE76364.1 - 0.087 12.9 0.0 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3899) Dpy19 PF10034.4 EIE76364.1 - 0.089 10.9 0.0 0.089 10.9 0.0 1.0 1 0 0 1 1 1 0 Q-cell neuroblast polarisation RabGAP-TBC PF00566.13 EIE76365.1 - 9.1e-34 116.8 0.4 1.3e-27 96.6 0.1 2.5 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Na_Ca_ex PF01699.19 EIE76366.1 - 2.2e-44 150.4 34.5 3.7e-25 88.1 9.0 3.6 3 1 1 4 4 4 2 Sodium/calcium exchanger protein NVEALA PF14055.1 EIE76366.1 - 0.033 13.8 0.3 0.25 11.0 0.2 2.6 1 0 0 1 1 1 0 NVEALA protein MLANA PF14991.1 EIE76366.1 - 1.9 8.5 4.0 3 7.8 0.0 3.3 3 0 0 3 3 3 0 Protein melan-A BolA PF01722.13 EIE76367.1 - 1.8e-23 82.2 0.2 2.1e-23 82.0 0.1 1.1 1 0 0 1 1 1 1 BolA-like protein PROCN PF08083.6 EIE76368.1 - 3.3e-222 737.2 4.8 6.1e-222 736.3 3.3 1.5 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 EIE76368.1 - 2.9e-128 425.9 0.4 4.9e-128 425.2 0.3 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 EIE76368.1 - 1.6e-90 300.6 2.2 3.6e-90 299.4 1.5 1.7 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 EIE76368.1 - 8.6e-84 278.7 4.1 2.1e-83 277.4 2.9 1.7 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 EIE76368.1 - 2.8e-69 230.9 0.0 5.5e-69 230.0 0.0 1.5 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.6 EIE76368.1 - 3e-46 156.1 0.1 7.7e-46 154.8 0.1 1.8 1 0 0 1 1 1 1 PROCT (NUC072) domain RRM_4 PF10598.4 EIE76368.1 - 1.3e-42 143.5 0.1 3.5e-42 142.1 0.1 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 JAB PF01398.16 EIE76368.1 - 4.2e-08 32.9 0.0 1.3e-07 31.3 0.0 1.8 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease E1_DerP2_DerF2 PF02221.10 EIE76369.1 - 0.0014 18.8 0.3 0.0021 18.3 0.2 1.3 1 0 0 1 1 1 1 ML domain DUF4625 PF15418.1 EIE76369.1 - 0.029 14.4 0.2 0.07 13.2 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4625) GPI-anchored PF10342.4 EIE76369.1 - 0.076 13.4 2.2 0.45 11.0 1.5 2.1 1 1 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF2648 PF10855.3 EIE76370.1 - 0.055 12.9 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2648) EXS PF03124.9 EIE76371.1 - 3.4e-89 299.2 28.9 4.6e-89 298.8 20.1 1.2 1 0 0 1 1 1 1 EXS family SPX PF03105.14 EIE76371.1 - 4.5e-39 134.8 16.0 4.5e-39 134.8 11.1 2.9 2 1 0 2 2 2 1 SPX domain Mit_KHE1 PF10173.4 EIE76372.1 - 1.5e-42 145.5 3.6 2.1e-42 145.1 2.5 1.2 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related GSu_C4xC__C2xCH PF09698.5 EIE76372.1 - 0.22 11.6 1.4 0.46 10.7 0.9 1.5 1 0 0 1 1 1 0 Geobacter CxxxxCH...CXXCH motif (GSu_C4xC__C2xCH) PLDc_2 PF13091.1 EIE76373.1 - 5.4e-06 26.1 0.0 1.1e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 PLD-like domain Kelch_3 PF13415.1 EIE76375.1 - 1.7e-49 164.9 19.6 7e-12 45.1 0.1 7.0 7 1 0 7 7 7 6 Galactose oxidase, central domain Kelch_4 PF13418.1 EIE76375.1 - 6.2e-41 137.9 15.8 7.6e-09 35.2 0.0 6.8 6 1 1 7 7 7 6 Galactose oxidase, central domain Kelch_5 PF13854.1 EIE76375.1 - 3e-38 129.1 8.5 2.7e-07 30.3 0.3 6.2 6 0 0 6 6 6 6 Kelch motif Kelch_1 PF01344.20 EIE76375.1 - 2.1e-36 123.1 5.0 1.6e-06 27.5 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 EIE76375.1 - 4.1e-33 112.1 13.9 2.1e-06 27.6 0.1 6.3 2 2 4 6 6 6 6 Kelch motif Kelch_2 PF07646.10 EIE76375.1 - 4.2e-30 102.3 2.6 3.5e-05 23.3 0.0 6.5 6 0 0 6 6 6 6 Kelch motif RAG2 PF03089.9 EIE76375.1 - 0.11 11.2 0.0 10 4.7 0.0 2.8 3 1 0 3 3 3 0 Recombination activating protein 2 DUF1664 PF07889.7 EIE76376.1 - 0.01 15.6 32.7 0.18 11.6 6.6 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Nif11 PF07862.6 EIE76376.1 - 0.027 14.4 3.5 0.09 12.7 0.1 3.3 2 2 0 2 2 2 0 Nitrogen fixation protein of unknown function DUF3584 PF12128.3 EIE76376.1 - 0.11 9.8 33.3 0.16 9.2 23.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF3423 PF11903.3 EIE76376.1 - 0.15 11.8 3.8 0.57 9.9 2.6 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3423) Cut8_M PF14483.1 EIE76376.1 - 0.65 9.8 3.7 0.43 10.4 0.4 2.4 2 0 0 2 2 2 0 Cut8 dimerisation domain YbaJ PF10757.4 EIE76376.1 - 1 9.5 4.2 1.3 9.2 0.1 2.4 2 1 0 2 2 2 0 Biofilm formation regulator YbaJ WEMBL PF05701.6 EIE76376.1 - 1.1 7.6 41.0 2.3 6.5 28.4 1.6 1 1 0 1 1 1 0 Weak chloroplast movement under blue light Peptidase_M27 PF01742.12 EIE76376.1 - 1.1 8.0 12.3 0.2 10.4 3.5 2.0 1 1 1 2 2 2 0 Clostridial neurotoxin zinc protease PMEI PF04043.10 EIE76376.1 - 1.4 8.8 4.3 5.7 6.8 0.6 2.5 2 1 1 3 3 3 0 Plant invertase/pectin methylesterase inhibitor TMV_coat PF00721.16 EIE76376.1 - 2.1 8.2 13.0 1.3 8.8 1.7 3.0 2 1 1 3 3 3 0 Virus coat protein (TMV like) APG6 PF04111.7 EIE76376.1 - 2.2 7.2 41.6 0.082 11.9 19.0 2.2 1 1 1 2 2 2 0 Autophagy protein Apg6 Apolipoprotein PF01442.13 EIE76376.1 - 4.8 6.6 40.1 19 4.6 18.7 2.8 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain TBPIP PF07106.8 EIE76376.1 - 5.4 6.5 37.7 2.4 7.7 17.5 3.0 1 1 3 4 4 4 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Spc7 PF08317.6 EIE76376.1 - 8.4 4.9 41.4 0.48 9.0 4.7 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein Lys PF00062.15 EIE76377.1 - 0.0062 16.5 0.0 0.009 15.9 0.0 1.3 1 0 0 1 1 1 1 C-type lysozyme/alpha-lactalbumin family Abhydrolase_6 PF12697.2 EIE76378.1 - 1.1e-22 81.1 0.0 1.3e-22 80.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EIE76378.1 - 2.1e-20 72.3 0.1 3.3e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_5 PF12695.2 EIE76378.1 - 2.1e-16 59.9 0.0 5.5e-16 58.6 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIE76378.1 - 8.4e-09 35.3 0.0 4.2e-07 29.7 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EIE76378.1 - 0.0025 17.0 0.8 0.045 12.9 0.2 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 EIE76378.1 - 0.0053 16.2 2.1 0.094 12.1 0.0 2.8 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase DUF1749 PF08538.5 EIE76378.1 - 0.013 14.3 0.0 0.026 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) DUF2305 PF10230.4 EIE76378.1 - 0.034 13.5 0.0 0.049 13.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Abhydrolase_3 PF07859.8 EIE76378.1 - 0.036 13.6 0.0 0.07 12.6 0.0 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.13 EIE76378.1 - 0.062 12.5 0.1 1.5 8.0 0.0 2.3 2 1 0 2 2 2 0 Dienelactone hydrolase family DUF3089 PF11288.3 EIE76378.1 - 0.099 11.7 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) DUF915 PF06028.6 EIE76378.1 - 0.12 11.4 0.1 1.7 7.6 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) UQ_con PF00179.21 EIE76379.1 - 4e-24 84.6 0.1 4.5e-24 84.4 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EIE76379.1 - 0.0093 15.8 0.1 0.01 15.7 0.0 1.2 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.1 EIE76379.1 - 0.11 12.2 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B PB1 PF00564.19 EIE76381.1 - 9.1e-13 47.6 0.9 1.9e-12 46.6 0.6 1.6 1 0 0 1 1 1 1 PB1 domain TPR_1 PF00515.23 EIE76381.1 - 0.0061 16.1 0.0 3.7 7.3 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat Pkinase PF00069.20 EIE76382.1 - 2.9e-51 174.0 0.0 5.8e-51 173.1 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE76382.1 - 1.4e-24 86.6 0.0 2.2e-24 85.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE76382.1 - 0.0007 18.6 0.1 0.0021 17.0 0.0 1.9 2 0 0 2 2 2 1 Kinase-like PX PF00787.19 EIE76382.1 - 0.0011 18.6 5.0 0.0021 17.8 3.5 1.5 1 0 0 1 1 1 1 PX domain APH PF01636.18 EIE76382.1 - 0.015 14.9 0.9 0.29 10.8 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family PDEase_I PF00233.14 EIE76384.1 - 1.6e-34 119.7 3.6 6.4e-23 81.7 0.0 3.3 2 1 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase Response_reg PF00072.19 EIE76384.1 - 0.056 13.4 0.0 0.15 12.0 0.0 1.7 2 0 0 2 2 2 0 Response regulator receiver domain HD PF01966.17 EIE76384.1 - 0.069 13.1 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 HD domain Glu_synthase PF01645.12 EIE76385.1 - 9.1e-155 515.0 0.0 1.4e-154 514.4 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase GATase_2 PF00310.16 EIE76385.1 - 2.5e-139 463.9 0.0 3.8e-139 463.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 EIE76385.1 - 3.2e-118 394.1 0.0 5e-118 393.5 0.0 1.3 1 0 0 1 1 1 1 Glutamate synthase central domain GXGXG PF01493.14 EIE76385.1 - 1.1e-66 223.7 1.1 1.9e-66 222.9 0.8 1.4 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.1 EIE76385.1 - 2.3e-22 78.7 0.1 5.5e-22 77.4 0.0 1.7 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 EIE76385.1 - 9.6e-20 71.3 0.6 2.4e-19 70.0 0.1 2.1 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EIE76385.1 - 1.9e-11 44.3 0.1 8e-05 22.7 0.1 2.7 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIE76385.1 - 1.1e-07 31.7 0.3 5.3e-07 29.5 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EIE76385.1 - 1.1e-06 28.9 0.2 0.002 18.4 0.1 2.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 EIE76385.1 - 3.6e-05 23.9 0.1 0.14 12.4 0.1 2.8 2 0 0 2 2 2 2 Putative NAD(P)-binding HI0933_like PF03486.9 EIE76385.1 - 4.1e-05 22.2 1.5 6.1e-05 21.6 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 EIE76385.1 - 4.7e-05 22.4 0.3 0.0017 17.2 0.0 2.6 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 EIE76385.1 - 6.1e-05 22.0 0.2 0.0015 17.5 0.0 2.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 EIE76385.1 - 8.2e-05 22.2 0.0 0.0068 15.9 0.0 2.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.19 EIE76385.1 - 0.001 18.2 0.1 0.0017 17.5 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Thi4 PF01946.12 EIE76385.1 - 0.0019 17.3 0.1 0.031 13.3 0.1 2.4 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 EIE76385.1 - 0.0032 16.5 0.0 0.0062 15.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EIE76385.1 - 0.0058 15.7 0.1 0.011 14.8 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Shikimate_DH PF01488.15 EIE76385.1 - 0.0095 16.0 0.1 6.9 6.7 0.0 2.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DJ-1_PfpI PF01965.19 EIE76385.1 - 0.013 14.9 0.3 0.56 9.6 0.1 2.4 1 1 1 2 2 2 0 DJ-1/PfpI family NAD_Gly3P_dh_N PF01210.18 EIE76385.1 - 0.017 14.8 0.5 0.056 13.1 0.0 2.1 3 0 0 3 3 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GATase_6 PF13522.1 EIE76385.1 - 0.024 14.5 0.0 0.071 13.0 0.0 1.8 1 0 0 1 1 1 0 Glutamine amidotransferase domain NAD_binding_9 PF13454.1 EIE76385.1 - 0.033 13.9 0.2 0.24 11.1 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_2 PF03446.10 EIE76385.1 - 0.042 13.6 0.1 0.17 11.7 0.1 2.1 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 EIE76385.1 - 0.043 12.9 0.0 0.3 10.2 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.17 EIE76385.1 - 0.1 11.4 1.4 0.23 10.2 0.1 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A 3HCDH_N PF02737.13 EIE76385.1 - 0.37 10.4 2.5 0.51 9.9 0.1 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain LSM14 PF12701.2 EIE76388.1 - 2.9e-36 123.1 0.0 2.9e-36 123.1 0.0 2.6 2 1 0 2 2 2 1 Scd6-like Sm domain FDF PF09532.5 EIE76388.1 - 6.4e-12 45.9 11.2 4.6e-10 39.9 0.9 4.5 1 1 2 3 3 3 2 FDF domain SM-ATX PF14438.1 EIE76388.1 - 0.00014 21.7 0.0 0.00014 21.7 0.0 2.2 2 0 0 2 2 2 1 Ataxin 2 SM domain Med15 PF09606.5 EIE76388.1 - 0.0074 14.5 57.1 0.0099 14.1 39.6 1.3 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal TFIIA PF03153.8 EIE76388.1 - 0.19 11.6 40.8 0.27 11.0 28.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 EIE76388.1 - 3.8 5.6 77.4 0.25 9.5 49.8 1.7 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 HSF_DNA-bind PF00447.12 EIE76389.1 - 1e-33 115.6 1.4 1e-33 115.6 1.0 1.9 2 0 0 2 2 2 1 HSF-type DNA-binding Baculo_PEP_C PF04513.7 EIE76389.1 - 0.019 14.8 1.0 0.21 11.4 0.1 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus CENP-F_leu_zip PF10473.4 EIE76389.1 - 0.22 11.3 5.7 0.4 10.5 1.9 2.3 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NPV_P10 PF05531.7 EIE76389.1 - 0.94 9.7 3.7 2.9 8.2 0.0 2.8 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Nup54 PF13874.1 EIE76389.1 - 1.5 8.4 6.4 39 3.8 2.5 2.7 2 1 1 3 3 3 0 Nucleoporin complex subunit 54 HMGL-like PF00682.14 EIE76390.1 - 8e-44 150.0 0.1 9.8e-44 149.7 0.1 1.0 1 0 0 1 1 1 1 HMGL-like Acyl-CoA_dh_1 PF00441.19 EIE76391.1 - 5.4e-30 104.4 1.0 8.3e-30 103.8 0.7 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EIE76391.1 - 9.1e-26 90.6 0.0 2e-25 89.5 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EIE76391.1 - 1.5e-20 72.4 0.0 2.5e-20 71.7 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EIE76391.1 - 1.2e-09 38.5 0.4 2.1e-09 37.7 0.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain TLD PF07534.11 EIE76392.1 - 1.8e-14 53.8 0.0 9.1e-10 38.6 0.1 2.4 1 1 1 2 2 2 2 TLD Galanin PF01296.13 EIE76392.1 - 3.5 7.5 7.0 5.2 6.9 0.1 2.9 2 1 1 3 3 3 0 Galanin BOP1NT PF08145.7 EIE76394.1 - 0.085 12.5 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 BOP1NT (NUC169) domain LrgB PF04172.11 EIE76395.1 - 2.3e-21 75.9 8.0 2.4e-21 75.8 5.5 1.0 1 0 0 1 1 1 1 LrgB-like family Bax1-I PF01027.15 EIE76395.1 - 0.01 15.4 5.9 0.012 15.2 4.1 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF1614 PF07758.6 EIE76395.1 - 0.15 11.8 6.1 0.31 10.7 0.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1614) DUF4064 PF13273.1 EIE76395.1 - 1.2 9.2 5.8 3.9 7.6 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) SH3_1 PF00018.23 EIE76396.1 - 3.1e-07 29.6 0.0 7.2e-07 28.4 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EIE76396.1 - 3.9e-05 23.1 0.0 8.4e-05 22.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Exo_endo_phos PF03372.18 EIE76398.1 - 2.7e-17 63.5 3.2 1.1e-16 61.5 2.2 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RhoGAP PF00620.22 EIE76398.1 - 1.4e-09 37.6 0.1 7.1e-09 35.4 0.0 2.3 2 1 0 2 2 2 1 RhoGAP domain Actin PF00022.14 EIE76400.1 - 3.9e-53 180.2 0.0 9.6e-53 179.0 0.0 1.4 1 1 1 2 2 2 1 Actin MreB_Mbl PF06723.8 EIE76400.1 - 1.8e-13 49.8 0.0 4.4e-10 38.6 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.1 EIE76400.1 - 0.0024 17.7 0.0 0.42 10.4 0.0 2.4 2 0 0 2 2 2 2 Cell division protein FtsA PilM_2 PF11104.3 EIE76400.1 - 0.041 12.7 0.0 1.7 7.4 0.0 2.2 2 0 0 2 2 2 0 Type IV pilus assembly protein PilM; NICE-3 PF07406.6 EIE76400.1 - 0.1 12.1 0.2 0.56 9.6 0.0 2.0 1 1 1 2 2 2 0 NICE-3 protein MutL PF13941.1 EIE76400.1 - 0.27 9.5 2.0 0.36 9.0 0.2 1.9 2 0 0 2 2 2 0 MutL protein DnaJ PF00226.26 EIE76401.1 - 1e-06 28.3 0.3 2.5e-06 27.1 0.0 1.7 2 0 0 2 2 2 1 DnaJ domain DUF2681 PF10883.3 EIE76401.1 - 0.031 14.4 0.7 0.031 14.4 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) DUF533 PF04391.7 EIE76403.1 - 0.028 13.8 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF533) Dicty_REP PF05086.7 EIE76404.1 - 7.1 4.2 18.4 9.6 3.8 12.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein FGGY_N PF00370.16 EIE76407.1 - 7.7e-73 244.8 0.1 1.3e-72 244.0 0.1 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 EIE76407.1 - 2.2e-66 223.2 3.1 2.2e-66 223.2 1.3 1.6 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain GCR1_C PF12550.3 EIE76408.1 - 5.1e-26 90.3 0.7 5.1e-25 87.1 0.2 2.6 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes Lys PF00062.15 EIE76409.1 - 0.0037 17.2 0.0 0.0054 16.7 0.0 1.3 1 0 0 1 1 1 1 C-type lysozyme/alpha-lactalbumin family YpzG PF14139.1 EIE76409.1 - 0.019 14.8 0.1 0.04 13.8 0.0 1.6 1 0 0 1 1 1 0 YpzG-like protein DDE_3 PF13358.1 EIE76411.1 - 0.00076 19.2 0.0 0.001 18.8 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease CotH PF08757.6 EIE76413.1 - 1.6e-29 103.2 7.0 3e-29 102.3 4.8 1.4 1 0 0 1 1 1 1 CotH protein F1F0-ATPsyn_F PF10791.4 EIE76414.1 - 6.8e-30 103.1 0.1 7.5e-30 103.0 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.4 EIE76414.1 - 4.9e-05 23.3 0.0 6.1e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial F1F0-ATP synthase, subunit f AAA_2 PF07724.9 EIE76415.1 - 0.011 15.7 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) G-alpha PF00503.15 EIE76416.1 - 3.5e-131 437.4 11.3 4.3e-131 437.1 7.9 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EIE76416.1 - 4.4e-17 61.8 3.5 2.7e-12 46.2 0.5 2.8 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EIE76416.1 - 9.9e-06 24.8 6.8 6e-05 22.3 0.4 2.7 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region zf-CHC2 PF01807.15 EIE76416.1 - 0.00036 20.0 0.4 0.001 18.6 0.1 1.9 2 0 0 2 2 2 1 CHC2 zinc finger Miro PF08477.8 EIE76416.1 - 0.001 19.5 0.2 1.7 9.1 0.0 2.9 2 1 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 EIE76416.1 - 0.024 14.1 0.2 0.089 12.3 0.2 1.9 1 1 1 2 2 2 0 P-loop containing region of AAA domain GTP_EFTU PF00009.22 EIE76416.1 - 0.028 13.8 0.3 1 8.7 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain DUF19 PF01579.13 EIE76416.1 - 0.032 14.2 2.4 0.062 13.2 1.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF19) MMR_HSR1 PF01926.18 EIE76416.1 - 0.051 13.5 0.1 1.1 9.1 0.1 2.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_14 PF13173.1 EIE76416.1 - 0.24 11.3 2.4 0.26 11.1 0.2 2.2 2 2 0 2 2 2 0 AAA domain Rad21_Rec8_N PF04825.8 EIE76417.1 - 1.3e-33 115.2 0.1 3e-33 114.0 0.0 1.6 2 0 0 2 2 2 1 N terminus of Rad21 / Rec8 like protein DUF977 PF06163.6 EIE76417.1 - 0.14 11.9 0.1 0.49 10.1 0.0 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF977) AA_permease PF00324.16 EIE76418.1 - 8.7e-121 403.5 42.3 1.1e-120 403.2 29.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EIE76418.1 - 2.8e-40 138.1 42.2 3.4e-40 137.8 29.2 1.0 1 0 0 1 1 1 1 Amino acid permease zf-CCHC PF00098.18 EIE76419.1 - 1.6e-07 30.8 10.2 1.6e-05 24.6 0.7 2.2 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 EIE76419.1 - 0.0017 17.9 4.9 0.24 11.0 0.5 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.1 EIE76419.1 - 0.018 14.4 6.1 0.046 13.2 1.2 2.3 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC_6 PF15288.1 EIE76419.1 - 0.044 13.4 10.7 0.13 11.9 0.9 3.0 2 1 1 3 3 3 0 Zinc knuckle Cmc1 PF08583.5 EIE76419.1 - 0.19 11.5 2.3 0.29 10.9 1.6 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Zn_ribbon_2 PF12674.2 EIE76419.1 - 0.92 9.8 3.6 4.8 7.5 2.5 2.2 1 1 0 1 1 1 0 Putative zinc ribbon domain DnaJ_CXXCXGXG PF00684.14 EIE76419.1 - 1.1 9.4 5.4 4.4 7.4 3.8 1.9 1 1 0 1 1 1 0 DnaJ central domain zf-CCHC_3 PF13917.1 EIE76419.1 - 5.1 6.9 8.2 1.5 8.6 0.9 2.2 1 1 1 2 2 2 0 Zinc knuckle Cpn60_TCP1 PF00118.19 EIE76422.1 - 5.6e-144 480.3 12.1 6.5e-144 480.1 8.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PcfK PF14058.1 EIE76422.1 - 0.14 12.3 0.3 0.24 11.5 0.2 1.3 1 0 0 1 1 1 0 PcfK-like protein PBD PF00786.23 EIE76423.1 - 4e-07 30.3 0.1 1.3e-06 28.7 0.1 1.9 1 0 0 1 1 1 1 P21-Rho-binding domain WH2 PF02205.15 EIE76423.1 - 0.0031 17.0 0.1 0.0063 16.0 0.1 1.5 1 0 0 1 1 1 1 WH2 motif Sulfate_transp PF00916.15 EIE76424.1 - 2e-75 253.3 8.8 2e-75 253.3 6.1 1.7 2 0 0 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EIE76424.1 - 2.4e-32 110.4 3.3 2.4e-32 110.4 2.3 4.1 4 1 0 4 4 4 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EIE76424.1 - 0.06 12.7 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 STAS domain OrfB_Zn_ribbon PF07282.6 EIE76425.1 - 5.2e-08 32.4 4.0 1.3e-07 31.1 2.7 1.7 1 0 0 1 1 1 1 Putative transposase DNA-binding domain Stanniocalcin PF03298.8 EIE76425.1 - 0.0078 15.2 0.1 0.0078 15.2 0.1 2.7 2 1 0 2 2 2 1 Stanniocalcin family DUF4298 PF14131.1 EIE76425.1 - 0.34 10.8 8.4 0.74 9.7 0.2 3.5 2 1 0 3 3 3 0 Domain of unknown function (DUF4298) Methyltransf_11 PF08241.7 EIE76426.1 - 2.4e-13 50.3 0.0 4.2e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIE76426.1 - 5.6e-12 45.4 0.0 1.3e-11 44.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIE76426.1 - 2.1e-11 43.8 0.0 2.9e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIE76426.1 - 2.4e-10 40.6 0.0 8.2e-10 38.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIE76426.1 - 4.7e-09 36.6 0.0 9.7e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIE76426.1 - 1.7e-08 33.8 0.0 6.8e-08 31.9 0.0 1.9 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EIE76426.1 - 5.1e-07 30.2 0.1 7.6e-06 26.4 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_2 PF00891.13 EIE76426.1 - 6.9e-07 28.7 0.0 1e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_26 PF13659.1 EIE76426.1 - 1.1e-05 25.4 0.0 2.4e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EIE76426.1 - 4.9e-05 23.0 0.0 0.0001 22.0 0.0 1.4 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_4 PF02390.12 EIE76426.1 - 0.00096 18.2 0.0 0.0044 16.0 0.0 2.1 3 0 0 3 3 3 1 Putative methyltransferase MTS PF05175.9 EIE76426.1 - 0.00098 18.5 0.0 0.0061 15.9 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase small domain MetW PF07021.7 EIE76426.1 - 0.002 17.5 0.0 0.0032 16.8 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW CMAS PF02353.15 EIE76426.1 - 0.0028 16.7 0.1 0.0051 15.9 0.0 1.5 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase TehB PF03848.9 EIE76426.1 - 0.019 14.1 0.0 0.069 12.3 0.0 1.7 1 1 1 2 2 2 0 Tellurite resistance protein TehB PCMT PF01135.14 EIE76426.1 - 0.055 12.9 0.0 0.097 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FmrO PF07091.6 EIE76426.1 - 0.07 12.1 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Methyltransf_9 PF08003.6 EIE76426.1 - 0.12 10.9 0.0 0.21 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) FUSC_2 PF13515.1 EIE76427.1 - 0.51 10.2 9.9 0.18 11.7 5.1 1.5 1 1 0 1 1 1 0 Fusaric acid resistance protein-like DUF1345 PF07077.6 EIE76427.1 - 0.61 9.5 4.5 1.8 8.0 3.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1345) CitMHS PF03600.11 EIE76427.1 - 0.82 8.1 11.3 0.98 7.9 7.9 1.1 1 0 0 1 1 1 0 Citrate transporter HlyIII PF03006.15 EIE76427.1 - 1.6 8.1 8.5 2.1 7.7 5.9 1.3 1 0 0 1 1 1 0 Haemolysin-III related DUF2207 PF09972.4 EIE76428.1 - 0.23 10.0 3.4 0.28 9.7 2.3 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) SHP PF03579.8 EIE76428.1 - 1.9 7.8 7.7 0.42 9.9 1.1 2.7 2 0 0 2 2 2 0 Small hydrophobic protein OrfB_Zn_ribbon PF07282.6 EIE76429.1 - 5.2e-08 32.4 4.0 1.3e-07 31.1 2.7 1.8 1 0 0 1 1 1 1 Putative transposase DNA-binding domain Stanniocalcin PF03298.8 EIE76429.1 - 0.0078 15.2 0.1 0.0078 15.2 0.1 2.7 2 1 0 2 2 2 1 Stanniocalcin family UPF0081 PF03652.10 EIE76429.1 - 0.13 12.3 0.0 0.59 10.2 0.0 2.3 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0081) DUF4298 PF14131.1 EIE76429.1 - 0.28 11.0 9.7 0.74 9.7 0.2 4.1 3 1 0 4 4 4 0 Domain of unknown function (DUF4298) AAA_16 PF13191.1 EIE76430.1 - 4.7e-08 33.2 0.1 0.00035 20.6 0.0 3.2 4 0 0 4 4 4 2 AAA ATPase domain AAA_22 PF13401.1 EIE76430.1 - 0.0016 18.6 0.6 0.016 15.3 0.0 2.9 3 1 0 3 3 3 1 AAA domain IstB_IS21 PF01695.12 EIE76430.1 - 0.037 13.4 0.0 0.17 11.2 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_17 PF13207.1 EIE76430.1 - 0.038 14.8 0.0 0.2 12.4 0.0 2.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EIE76430.1 - 0.049 13.5 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EIE76430.1 - 0.054 13.1 0.0 1.8 8.2 0.0 2.3 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.17 EIE76430.1 - 0.064 13.4 0.0 0.19 11.9 0.0 1.8 1 0 0 1 1 1 0 RNA helicase DUF258 PF03193.11 EIE76430.1 - 0.066 12.4 0.0 0.15 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 PH PF00169.24 EIE76431.1 - 2.9e-11 43.4 0.1 7e-10 39.0 0.0 2.9 2 0 0 2 2 2 1 PH domain PH_9 PF15410.1 EIE76431.1 - 0.0064 16.6 0.3 0.18 11.9 0.0 2.8 2 0 0 2 2 2 1 Pleckstrin homology domain Abhydro_lipase PF04083.11 EIE76432.1 - 0.063 12.6 0.1 0.14 11.5 0.1 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region GLTSCR1 PF15249.1 EIE76433.1 - 6.6e-22 77.6 0.8 6.6e-22 77.6 0.5 2.3 2 1 0 2 2 2 1 Glioma tumor suppressor candidate region PRKCSH-like PF12999.2 EIE76433.1 - 3.4 7.2 6.9 15 5.0 0.2 2.3 2 0 0 2 2 2 0 Glucosidase II beta subunit-like CotH PF08757.6 EIE76435.1 - 5.1e-37 127.8 3.9 6.9e-37 127.3 2.7 1.2 1 0 0 1 1 1 1 CotH protein Colicin_im PF03857.8 EIE76435.1 - 0.016 14.9 0.0 0.034 13.8 0.0 1.4 1 0 0 1 1 1 0 Colicin immunity protein Homeobox PF00046.24 EIE76436.1 - 2.5e-08 33.3 1.8 5.8e-08 32.2 1.2 1.6 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EIE76436.1 - 0.0014 18.3 2.3 0.023 14.3 0.1 2.6 2 0 0 2 2 2 1 Homeobox KN domain CDC45 PF02724.9 EIE76436.1 - 0.13 10.2 3.8 0.16 9.9 2.6 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2335 PF10097.4 EIE76436.1 - 0.3 10.7 2.2 0.67 9.6 1.5 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2335) Aa_trans PF01490.13 EIE76437.1 - 5.7e-90 301.7 36.9 6.5e-90 301.5 25.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EIE76437.1 - 9.8e-06 24.6 18.4 9.8e-06 24.6 12.8 2.2 1 1 0 2 2 2 1 Tryptophan/tyrosine permease family CAAD PF14159.1 EIE76437.1 - 0.2 11.3 5.2 1.1 8.8 1.7 3.1 2 1 0 2 2 2 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase CAF1 PF04857.15 EIE76438.1 - 2.4e-31 109.0 0.0 2.8e-31 108.7 0.0 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease Ribonucleas_3_3 PF14622.1 EIE76439.1 - 9.1e-24 83.8 0.0 1.5e-23 83.1 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 EIE76439.1 - 9.3e-10 38.9 0.0 2.4e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 Ribonuclease III domain dsrm PF00035.20 EIE76439.1 - 2.9e-06 27.7 0.8 4.2e-06 27.2 0.0 1.6 2 0 0 2 2 2 1 Double-stranded RNA binding motif DUF1712 PF08217.6 EIE76440.1 - 1.3e-31 109.5 13.4 7e-30 103.8 0.3 2.4 2 1 0 2 2 2 2 Fungal domain of unknown function (DUF1712) SWIM PF04434.12 EIE76443.1 - 1.7e-05 24.2 0.6 3e-05 23.3 0.4 1.3 1 0 0 1 1 1 1 SWIM zinc finger Lipocalin PF00061.18 EIE76443.1 - 0.005 16.8 0.0 0.0083 16.1 0.0 1.3 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family IPK PF03770.11 EIE76443.1 - 0.043 13.4 0.0 0.051 13.1 0.0 1.2 1 0 0 1 1 1 0 Inositol polyphosphate kinase SF3a60_bindingd PF12108.3 EIE76443.1 - 0.095 12.2 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain MULE PF10551.4 EIE76444.1 - 6e-06 26.3 0.1 2.4e-05 24.4 0.0 2.0 1 1 1 2 2 2 1 MULE transposase domain FAR1 PF03101.10 EIE76444.1 - 0.00017 22.0 0.5 0.00039 20.8 0.3 1.5 1 0 0 1 1 1 1 FAR1 DNA-binding domain YPEB PF14620.1 EIE76446.1 - 0.1 11.5 3.2 0.16 10.9 2.2 1.2 1 0 0 1 1 1 0 YpeB sporulation DUF2730 PF10805.3 EIE76446.1 - 0.13 11.9 1.0 0.84 9.4 0.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) Ima1_N PF09779.4 EIE76446.1 - 0.59 10.6 4.6 0.54 10.7 0.5 2.8 2 1 1 3 3 3 0 Ima1 N-terminal domain TEX13 PF15186.1 EIE76446.1 - 0.62 9.6 3.9 0.2 11.2 0.5 1.7 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family DDE_3 PF13358.1 EIE76447.1 - 0.029 14.0 1.9 0.045 13.4 1.4 1.5 1 1 0 1 1 1 0 DDE superfamily endonuclease RVT_1 PF00078.22 EIE76449.1 - 1.8e-20 73.2 0.0 8.1e-20 71.1 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DivIC PF04977.10 EIE76451.1 - 0.0056 16.1 0.9 0.0099 15.3 0.6 1.3 1 0 0 1 1 1 1 Septum formation initiator SlyX PF04102.7 EIE76451.1 - 0.022 15.1 0.3 0.059 13.7 0.2 1.8 1 0 0 1 1 1 0 SlyX Rab5-bind PF09311.6 EIE76451.1 - 0.039 13.8 0.3 0.069 13.0 0.2 1.3 1 0 0 1 1 1 0 Rabaptin-like protein RVT_1 PF00078.22 EIE76452.1 - 5.9e-27 94.4 0.0 7.9e-27 94.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EIE76453.1 - 2.1e-18 66.0 4.2 3.3e-18 65.4 1.7 2.2 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EIE76453.1 - 4.6e-07 30.0 0.5 9.3e-07 29.0 0.1 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Glyco_trans_1_2 PF13524.1 EIE76453.1 - 0.13 12.5 0.8 1.5 9.1 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferases group 1 DDE_3 PF13358.1 EIE76454.1 - 0.029 14.0 1.9 0.045 13.4 1.4 1.5 1 1 0 1 1 1 0 DDE superfamily endonuclease YPEB PF14620.1 EIE76455.1 - 0.1 11.5 3.2 0.16 10.9 2.2 1.2 1 0 0 1 1 1 0 YpeB sporulation DUF2730 PF10805.3 EIE76455.1 - 0.13 11.9 1.0 0.84 9.4 0.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) Ima1_N PF09779.4 EIE76455.1 - 0.59 10.6 4.6 0.54 10.7 0.5 2.8 2 1 1 3 3 3 0 Ima1 N-terminal domain TEX13 PF15186.1 EIE76455.1 - 0.62 9.6 3.9 0.2 11.2 0.5 1.7 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family SWIM PF04434.12 EIE76457.1 - 1.7e-05 24.2 0.6 3e-05 23.3 0.4 1.3 1 0 0 1 1 1 1 SWIM zinc finger Lipocalin PF00061.18 EIE76457.1 - 0.005 16.8 0.0 0.0083 16.1 0.0 1.3 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family IPK PF03770.11 EIE76457.1 - 0.043 13.4 0.0 0.051 13.1 0.0 1.2 1 0 0 1 1 1 0 Inositol polyphosphate kinase SF3a60_bindingd PF12108.3 EIE76457.1 - 0.095 12.2 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain MULE PF10551.4 EIE76458.1 - 6e-06 26.3 0.1 2.4e-05 24.4 0.0 2.0 1 1 1 2 2 2 1 MULE transposase domain FAR1 PF03101.10 EIE76458.1 - 0.00017 22.0 0.5 0.00039 20.8 0.3 1.5 1 0 0 1 1 1 1 FAR1 DNA-binding domain Med4 PF10018.4 EIE76460.1 - 8.4e-05 22.0 1.7 0.00011 21.6 1.2 1.3 1 1 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 Bestrophin PF01062.16 EIE76461.1 - 9.2e-52 175.7 0.0 6e-30 104.1 0.0 2.2 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel DUF3198 PF11433.3 EIE76461.1 - 0.27 11.1 1.4 0.86 9.5 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3198) Exo_endo_phos PF03372.18 EIE76465.1 - 0.0061 16.5 0.0 0.0064 16.4 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RVT_1 PF00078.22 EIE76466.1 - 0.0042 16.4 0.0 0.0046 16.3 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.18 EIE76467.1 - 2.5e-08 34.1 0.7 7.2e-08 32.6 0.5 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EIE76467.1 - 1.1e-07 31.4 0.2 4.2e-07 29.5 0.1 2.0 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase GPI-anchored PF10342.4 EIE76469.1 - 3.6e-16 59.4 9.7 3.6e-16 59.4 6.7 2.0 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family PAH PF02671.16 EIE76470.1 - 2.3e-50 167.9 3.4 2.7e-19 68.5 1.4 3.5 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 EIE76470.1 - 3.3e-36 123.0 0.9 3.3e-36 123.0 0.6 2.7 3 0 0 3 3 3 1 Sin3 family co-repressor Aminotran_1_2 PF00155.16 EIE76471.1 - 7.2e-31 107.4 0.0 9.9e-31 106.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DUF2540 PF10802.3 EIE76471.1 - 0.024 14.2 1.0 1.4 8.6 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2540) Tagatose_6_P_K PF08013.6 EIE76471.1 - 0.047 12.1 0.0 0.074 11.4 0.0 1.2 1 0 0 1 1 1 0 Tagatose 6 phosphate kinase Pkinase PF00069.20 EIE76472.1 - 6e-60 202.5 0.0 3e-38 131.4 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIE76472.1 - 1.4e-27 96.4 0.0 7.2e-22 77.6 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.19 EIE76472.1 - 2.3e-16 59.7 1.1 9.2e-16 57.8 0.5 2.2 2 0 0 2 2 2 1 Response regulator receiver domain Kinase-like PF14531.1 EIE76472.1 - 0.00011 21.2 0.0 0.00096 18.1 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EIE76472.1 - 0.00033 20.4 0.0 0.00071 19.3 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family PAS_9 PF13426.1 EIE76472.1 - 0.0016 18.7 0.0 0.011 16.0 0.0 2.5 2 0 0 2 2 2 1 PAS domain PAS_3 PF08447.6 EIE76472.1 - 0.0018 18.3 0.0 0.0042 17.1 0.0 1.7 1 0 0 1 1 1 1 PAS fold Seadorna_VP7 PF07387.6 EIE76472.1 - 0.17 10.7 0.0 0.34 9.6 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Steroid_dh PF02544.11 EIE76473.1 - 3e-34 117.9 8.0 3.3e-34 117.7 4.7 1.7 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase ubiquitin PF00240.18 EIE76473.1 - 0.00017 20.8 0.3 0.00026 20.3 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin family Carn_acyltransf PF00755.15 EIE76474.1 - 5.3e-77 259.2 0.3 7.5e-42 143.2 0.0 2.0 1 1 1 2 2 2 2 Choline/Carnitine o-acyltransferase C2 PF00168.25 EIE76475.1 - 4e-07 29.7 0.0 6.4e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 C2 domain NT-C2 PF10358.4 EIE76475.1 - 0.06 12.8 0.0 0.09 12.2 0.0 1.2 1 0 0 1 1 1 0 N-terminal C2 in EEIG1 and EHBP1 proteins Ran_BP1 PF00638.13 EIE76476.1 - 3.6e-49 165.8 2.0 5.7e-49 165.2 1.4 1.3 1 0 0 1 1 1 1 RanBP1 domain DUF1681 PF07933.9 EIE76476.1 - 5.4e-07 29.3 1.7 7.6e-07 28.8 1.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) WH1 PF00568.18 EIE76476.1 - 0.001 18.7 1.2 0.011 15.4 0.9 2.0 1 1 0 1 1 1 1 WH1 domain DUF4494 PF14902.1 EIE76476.1 - 0.0082 15.7 2.1 0.0082 15.7 1.4 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4494) Ribosomal_S9 PF00380.14 EIE76476.1 - 0.024 14.8 0.2 0.027 14.7 0.1 1.4 1 1 0 1 1 1 0 Ribosomal protein S9/S16 DUF1206 PF06724.6 EIE76477.1 - 9e-13 47.7 10.0 2e-09 37.0 0.9 2.3 2 0 0 2 2 2 2 Domain of Unknown Function (DUF1206) DUF2189 PF09955.4 EIE76477.1 - 0.0013 18.7 1.3 0.42 10.5 0.0 2.3 2 0 0 2 2 2 2 Predicted integral membrane protein (DUF2189) DUF2976 PF11190.3 EIE76477.1 - 0.16 11.4 1.6 8.9 5.9 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) ABC2_membrane_4 PF12730.2 EIE76477.1 - 0.2 10.8 3.0 0.79 8.8 2.1 1.8 1 1 0 1 1 1 0 ABC-2 family transporter protein EI24 PF07264.6 EIE76477.1 - 0.78 9.1 5.6 0.75 9.1 0.8 2.0 1 1 0 2 2 2 0 Etoposide-induced protein 2.4 (EI24) zf-RING_5 PF14634.1 EIE76478.1 - 8.8e-08 31.7 18.2 2e-06 27.4 9.9 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EIE76478.1 - 1.2e-06 28.4 18.7 5.5e-06 26.2 10.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIE76478.1 - 2e-06 27.3 21.1 2.2e-06 27.2 11.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EIE76478.1 - 2.2e-06 27.2 17.3 1e-05 25.1 9.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 EIE76478.1 - 2.4e-06 27.2 4.5 2.4e-06 27.2 3.2 2.0 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 EIE76478.1 - 7.2e-06 25.5 12.1 0.00025 20.5 3.7 3.4 3 0 0 3 3 3 2 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.1 EIE76478.1 - 3.2e-05 23.6 18.8 0.00013 21.6 10.0 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.1 EIE76478.1 - 0.00031 20.3 10.0 0.00031 20.3 7.0 2.7 2 0 0 2 2 2 1 RING-type zinc-finger zf-C2HC_2 PF13913.1 EIE76478.1 - 0.0049 16.4 4.7 0.28 10.8 0.0 3.5 3 0 0 3 3 3 1 zinc-finger of a C2HC-type zf-C3HC4_4 PF15227.1 EIE76478.1 - 0.031 14.1 14.4 0.031 14.1 10.0 2.4 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING PRP21_like_P PF12230.3 EIE76478.1 - 0.033 13.6 0.1 0.55 9.7 0.0 2.2 2 0 0 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein zf-Apc11 PF12861.2 EIE76478.1 - 0.036 13.9 9.3 0.066 13.0 3.4 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 EIE76478.1 - 0.045 13.8 13.4 0.07 13.2 7.3 2.4 2 1 0 2 2 2 0 RING-H2 zinc finger CcmH PF03918.9 EIE76478.1 - 0.24 10.4 1.5 1.1 8.2 0.0 2.3 2 0 0 2 2 2 0 Cytochrome C biogenesis protein zinc_ribbon_5 PF13719.1 EIE76478.1 - 0.55 9.8 10.0 3.6 7.2 0.0 3.8 4 0 0 4 4 4 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EIE76478.1 - 1.2 8.8 9.7 8.9 6.1 0.0 3.8 4 0 0 4 4 4 0 zinc-ribbon domain zf-H2C2_2 PF13465.1 EIE76478.1 - 1.5 9.2 6.4 30 5.1 0.1 3.7 3 0 0 3 3 3 0 Zinc-finger double domain zf-Nse PF11789.3 EIE76478.1 - 3.1 7.3 11.8 15 5.1 6.0 2.4 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-Di19 PF05605.7 EIE76478.1 - 3.1 7.9 16.1 10 6.3 0.2 2.7 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zinc-ribbons_6 PF07191.7 EIE76478.1 - 4.6 7.0 14.7 22 4.9 6.7 2.9 2 1 1 3 3 3 0 zinc-ribbons DUF4203 PF13886.1 EIE76479.1 - 1.1e-14 54.4 20.9 1.2e-14 54.2 14.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) NfeD PF01957.13 EIE76479.1 - 4.9 7.2 12.8 0.19 11.8 1.2 2.3 1 1 1 2 2 2 0 NfeD-like C-terminal, partner-binding F-box-like PF12937.2 EIE76480.1 - 5.9e-06 25.9 0.5 1.7e-05 24.4 0.4 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIE76480.1 - 0.015 14.9 0.1 0.051 13.2 0.0 1.9 1 0 0 1 1 1 0 F-box domain DUF2636 PF11120.3 EIE76480.1 - 0.017 14.6 0.0 10 5.7 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2636) vMSA PF00695.14 EIE76481.1 - 0.97 8.5 3.6 1.3 8.1 2.2 1.4 1 1 0 1 1 1 0 Major surface antigen from hepadnavirus Xpo1 PF08389.7 EIE76482.1 - 9e-06 25.6 8.2 0.00021 21.2 0.2 4.1 2 1 2 4 4 4 2 Exportin 1-like protein Chrome_Resist PF09828.4 EIE76482.1 - 0.078 13.1 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Chromate resistance exported protein HEAT PF02985.17 EIE76482.1 - 0.083 13.0 4.3 57 4.1 0.0 5.2 4 1 0 4 4 4 0 HEAT repeat Acetyltransf_1 PF00583.19 EIE76483.1 - 1.5e-15 56.9 0.0 2.2e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EIE76483.1 - 3.6e-06 27.0 0.0 5.9e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EIE76483.1 - 1e-05 25.6 0.0 1.5e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EIE76483.1 - 5.4e-05 22.8 0.1 0.0001 21.9 0.0 1.5 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_9 PF13527.1 EIE76483.1 - 0.00023 21.0 0.1 0.00058 19.7 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EIE76483.1 - 0.00077 19.6 0.0 0.0011 19.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EIE76483.1 - 0.019 14.9 0.0 0.025 14.5 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF1999 PF09390.5 EIE76483.1 - 0.096 12.0 0.0 0.28 10.5 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1999) DUF3749 PF12568.3 EIE76483.1 - 0.096 12.2 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain HTH_Tnp_Tc3_2 PF01498.13 EIE76484.1 - 7.6e-16 57.9 0.1 1.5e-15 56.9 0.1 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.1 EIE76484.1 - 4.5e-08 32.9 0.1 7e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_33 PF13592.1 EIE76484.1 - 1.8e-06 27.3 0.2 5.3e-06 25.8 0.0 1.9 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.1 EIE76484.1 - 9.4e-06 26.3 0.0 0.0003 21.5 0.0 2.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_21 PF13276.1 EIE76484.1 - 0.0009 19.2 0.0 0.0031 17.4 0.0 1.9 2 0 0 2 2 2 1 HTH-like domain HTH_29 PF13551.1 EIE76484.1 - 0.0011 19.0 0.0 0.003 17.7 0.0 1.8 1 0 0 1 1 1 1 Winged helix-turn helix Acetyltransf_2 PF00797.12 EIE76484.1 - 0.045 13.3 0.2 8.5 5.8 0.1 2.5 2 1 1 3 3 3 0 N-acetyltransferase HTH_Tnp_Tc3_2 PF01498.13 EIE76486.1 - 5.9e-07 29.4 0.1 1.1e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.1 EIE76486.1 - 0.041 13.6 0.1 0.12 12.1 0.1 1.7 2 0 0 2 2 2 0 DDE superfamily endonuclease DUF972 PF06156.8 EIE76487.1 - 1.2e-05 25.5 1.2 1.7e-05 25.0 0.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF972) TSC22 PF01166.13 EIE76487.1 - 0.00067 19.5 4.0 0.00087 19.2 2.3 1.4 1 1 0 1 1 1 1 TSC-22/dip/bun family DUF904 PF06005.7 EIE76487.1 - 0.005 17.0 1.9 0.0075 16.5 1.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF904) Tropomyosin_1 PF12718.2 EIE76487.1 - 0.032 14.0 1.1 0.043 13.6 0.8 1.2 1 0 0 1 1 1 0 Tropomyosin like CENP-Q PF13094.1 EIE76487.1 - 0.039 13.9 2.1 0.065 13.2 1.4 1.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF2216 PF10226.4 EIE76487.1 - 0.048 13.1 0.0 0.058 12.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved proteins (DUF2216) Syntaxin PF00804.20 EIE76487.1 - 0.049 13.7 0.5 0.068 13.3 0.4 1.4 1 0 0 1 1 1 0 Syntaxin bZIP_1 PF00170.16 EIE76487.1 - 0.054 13.4 2.7 0.12 12.4 1.9 1.5 1 0 0 1 1 1 0 bZIP transcription factor DivIC PF04977.10 EIE76487.1 - 0.063 12.7 1.3 0.12 11.8 0.9 1.4 1 0 0 1 1 1 0 Septum formation initiator BBS2_C PF14782.1 EIE76487.1 - 0.094 11.2 0.3 0.12 10.9 0.2 1.1 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal T4SS PF07996.6 EIE76487.1 - 0.11 12.3 0.1 0.16 11.8 0.1 1.3 1 0 0 1 1 1 0 Type IV secretion system proteins IncA PF04156.9 EIE76487.1 - 0.17 11.4 1.4 0.24 10.9 1.0 1.3 1 0 0 1 1 1 0 IncA protein DUF4200 PF13863.1 EIE76487.1 - 0.27 11.1 4.4 0.45 10.4 3.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Med9 PF07544.8 EIE76487.1 - 0.41 10.3 4.3 1.5 8.6 3.0 1.8 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 FKBP_N PF01346.13 EIE76488.1 - 0.0032 17.4 2.6 0.0056 16.7 1.8 1.3 1 0 0 1 1 1 1 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase DUF1853 PF08907.6 EIE76488.1 - 0.048 12.8 0.6 0.063 12.4 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1853) HTH_37 PF13744.1 EIE76488.1 - 0.052 13.3 5.1 6.3 6.6 3.7 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain DivIC PF04977.10 EIE76488.1 - 4.5 6.8 7.3 3.6 7.1 3.6 1.8 2 0 0 2 2 2 0 Septum formation initiator Transposase_21 PF02992.9 EIE76489.1 - 3.2e-20 72.2 0.0 5.6e-20 71.3 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 Ycf15 PF10705.4 EIE76489.1 - 0.032 14.2 0.3 0.44 10.6 0.3 2.4 2 0 0 2 2 2 0 Chloroplast protein precursor Ycf15 putative 3HCDH_N PF02737.13 EIE76489.1 - 0.17 11.4 0.0 0.34 10.5 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DDE_3 PF13358.1 EIE76490.1 - 7.1e-19 68.0 0.3 5.3e-18 65.1 0.0 2.4 3 0 0 3 3 3 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE76490.1 - 3.7e-10 39.7 0.6 9.1e-10 38.4 0.4 1.7 1 0 0 1 1 1 1 Transposase Matrilin_ccoil PF10393.4 EIE76493.1 - 0.0071 15.6 0.3 0.013 14.8 0.2 1.4 1 0 0 1 1 1 1 Trimeric coiled-coil oligomerisation domain of matrilin Mod_r PF07200.8 EIE76493.1 - 0.068 13.0 0.1 0.081 12.8 0.1 1.1 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein DivIC PF04977.10 EIE76493.1 - 0.074 12.5 1.0 0.12 11.8 0.6 1.4 1 1 0 1 1 1 0 Septum formation initiator DUF3450 PF11932.3 EIE76493.1 - 0.082 12.1 0.1 0.096 11.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Reo_sigmaC PF04582.7 EIE76493.1 - 0.09 11.9 0.5 0.1 11.7 0.3 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein bZIP_1 PF00170.16 EIE76493.1 - 0.1 12.5 2.6 0.16 11.9 1.6 1.4 1 1 0 1 1 1 0 bZIP transcription factor DUF1395 PF07160.7 EIE76493.1 - 0.11 11.9 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1395) TMF_DNA_bd PF12329.3 EIE76493.1 - 0.21 11.4 3.3 4.3 7.2 0.7 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF904 PF06005.7 EIE76493.1 - 0.31 11.3 2.7 1.1 9.6 2.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF904) Transposase_21 PF02992.9 EIE76495.1 - 6.9e-22 77.6 0.0 1e-21 77.0 0.0 1.2 1 0 0 1 1 1 1 Transposase family tnp2 DUF1258 PF06869.7 EIE76495.1 - 0.002 17.2 0.0 0.0031 16.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) LysR_substrate PF03466.15 EIE76495.1 - 0.15 11.1 0.0 0.27 10.2 0.0 1.3 1 0 0 1 1 1 0 LysR substrate binding domain Adeno_terminal PF02459.10 EIE76497.1 - 0.071 11.2 1.4 0.088 10.9 1.0 1.0 1 0 0 1 1 1 0 Adenoviral DNA terminal protein rve PF00665.21 EIE76499.1 - 1.9e-22 79.6 0.0 4.7e-22 78.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE76499.1 - 1.5e-15 57.1 0.1 2.9e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.12 EIE76499.1 - 8.5e-09 35.3 0.1 2.4e-08 33.9 0.1 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein Chromo PF00385.19 EIE76499.1 - 4.4e-08 32.6 0.1 1e-07 31.5 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.1 EIE76499.1 - 5.3e-05 23.6 0.0 0.00012 22.4 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.5 EIE76499.1 - 0.00044 19.5 1.6 0.0015 17.8 1.1 2.0 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Asp_protease PF09668.5 EIE76499.1 - 0.0082 15.7 0.0 0.019 14.5 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EIE76499.1 - 0.023 14.4 0.0 0.058 13.2 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease UBN2 PF14223.1 EIE76499.1 - 0.14 11.9 0.0 0.37 10.5 0.0 1.8 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type tRNA_SAD PF07973.9 EIE76500.1 - 0.41 10.5 1.7 0.59 10.0 1.2 1.3 1 0 0 1 1 1 0 Threonyl and Alanyl tRNA synthetase second additional domain HTH_Tnp_Tc3_2 PF01498.13 EIE76501.1 - 3.2e-11 43.1 2.4 3.3e-11 43.0 0.6 1.8 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.1 EIE76501.1 - 0.0033 17.0 0.0 0.008 15.7 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_30 PF13556.1 EIE76501.1 - 0.012 15.2 0.0 0.12 12.0 0.0 2.1 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain HTH_29 PF13551.1 EIE76501.1 - 0.013 15.6 0.3 0.023 14.8 0.0 1.6 2 0 0 2 2 2 0 Winged helix-turn helix DDE_3 PF13358.1 EIE76501.1 - 0.051 13.3 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 DDE superfamily endonuclease Lzipper-MIP1 PF14389.1 EIE76502.1 - 0.0049 16.9 0.4 0.013 15.5 0.3 1.7 1 0 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 ChaB PF06150.7 EIE76502.1 - 0.069 12.9 0.6 0.25 11.1 0.1 2.2 2 0 0 2 2 2 0 ChaB DUF4404 PF14357.1 EIE76502.1 - 0.16 12.3 1.9 5.7 7.4 0.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) IncA PF04156.9 EIE76502.1 - 0.17 11.4 1.2 0.28 10.7 0.9 1.4 1 0 0 1 1 1 0 IncA protein SRR PF07709.6 EIE76502.1 - 0.23 11.7 4.4 5.5 7.6 0.0 3.5 3 0 0 3 3 3 0 Seven Residue Repeat Transposase_21 PF02992.9 EIE76503.1 - 1.6e-17 63.3 0.0 1.6e-17 63.3 0.0 1.6 2 0 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.1 EIE76503.1 - 0.00055 19.3 0.0 0.0013 18.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) rve PF00665.21 EIE76504.1 - 5.2e-24 84.6 0.0 2e-23 82.7 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 EIE76504.1 - 1.2e-13 50.9 0.1 3.2e-13 49.5 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE76504.1 - 8.8e-09 34.9 0.9 1.1e-07 31.4 0.1 3.0 3 0 0 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.12 EIE76504.1 - 2.1e-06 27.7 0.2 2.1e-06 27.7 0.1 2.9 2 0 0 2 2 2 1 Retrotransposon gag protein rve_3 PF13683.1 EIE76504.1 - 0.0072 15.8 0.0 0.023 14.2 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain HTH_Tnp_Tc3_2 PF01498.13 EIE76505.1 - 1.9e-07 31.0 0.5 5.8e-07 29.4 0.1 1.8 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 EIE76505.1 - 0.0012 18.9 0.1 0.0028 17.7 0.0 1.6 2 0 0 2 2 2 1 Winged helix-turn helix HTH_17 PF12728.2 EIE76505.1 - 0.027 14.7 0.0 0.042 14.0 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain RRM_1 PF00076.17 EIE76506.1 - 4.7e-18 64.5 0.0 7.6e-18 63.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE76506.1 - 1.9e-13 50.1 0.0 3.7e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE76506.1 - 5.9e-10 38.8 0.0 9.4e-10 38.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 EIE76506.1 - 1e-07 32.2 5.0 1e-07 32.2 3.5 4.2 3 1 2 5 5 5 1 C-terminal duplication domain of Friend of PRMT1 Nup35_RRM_2 PF14605.1 EIE76506.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DAO PF01266.19 EIE76507.1 - 1.3e-15 57.1 0.0 2.5e-15 56.2 0.0 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIE76507.1 - 8.6e-14 51.3 0.0 1.7e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EIE76507.1 - 2.3e-07 30.2 0.0 9.3e-06 24.9 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EIE76507.1 - 3.7e-07 29.3 0.4 9.1e-06 24.7 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EIE76507.1 - 1.1e-06 28.6 0.0 8.7e-06 25.7 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EIE76507.1 - 1.5e-05 25.3 2.2 0.0062 16.9 0.6 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EIE76507.1 - 1.9e-05 23.8 0.0 4.2e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Amino_oxidase PF01593.19 EIE76507.1 - 5.6e-05 22.3 0.0 0.00015 20.9 0.0 1.8 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.14 EIE76507.1 - 8.2e-05 21.8 0.2 0.00013 21.1 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 EIE76507.1 - 0.00048 19.9 1.0 0.02 14.7 0.2 2.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.9 EIE76507.1 - 0.00069 18.1 0.8 0.0018 16.8 0.1 1.8 2 0 0 2 2 2 1 HI0933-like protein GDI PF00996.13 EIE76507.1 - 0.0031 15.9 0.0 0.0058 15.0 0.0 1.4 1 0 0 1 1 1 1 GDP dissociation inhibitor GIDA PF01134.17 EIE76507.1 - 0.0059 15.5 0.7 0.0059 15.5 0.5 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A UDPG_MGDP_dh_N PF03721.9 EIE76507.1 - 0.0071 15.7 0.2 0.088 12.1 0.0 2.2 2 1 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.1 EIE76507.1 - 0.0073 16.5 0.0 0.015 15.5 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding AlaDh_PNT_C PF01262.16 EIE76507.1 - 0.02 14.4 0.1 0.034 13.6 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.7 EIE76507.1 - 0.025 13.5 0.2 0.048 12.5 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein ApbA PF02558.11 EIE76507.1 - 0.026 13.9 0.7 0.1 12.0 0.4 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 EIE76507.1 - 0.029 14.0 0.9 0.057 13.0 0.6 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 EIE76507.1 - 0.032 14.2 0.3 0.13 12.2 0.2 1.9 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox_3 PF13738.1 EIE76507.1 - 0.033 14.2 0.1 0.47 10.4 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EIE76507.1 - 0.041 12.5 1.4 0.067 11.8 0.4 1.7 2 0 0 2 2 2 0 Tryptophan halogenase IlvN PF07991.7 EIE76507.1 - 0.074 12.4 0.3 0.16 11.3 0.2 1.6 2 0 0 2 2 1 0 Acetohydroxy acid isomeroreductase, catalytic domain NAD_Gly3P_dh_N PF01210.18 EIE76507.1 - 0.086 12.5 0.4 0.17 11.5 0.3 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ThiF PF00899.16 EIE76507.1 - 0.098 12.4 0.4 0.34 10.7 0.1 2.0 3 0 0 3 3 2 0 ThiF family GMC_oxred_N PF00732.14 EIE76507.1 - 0.098 11.7 0.4 9.7 5.2 0.0 2.1 2 0 0 2 2 2 0 GMC oxidoreductase 2-Hacid_dh_C PF02826.14 EIE76507.1 - 0.24 10.5 0.7 0.56 9.3 0.4 1.6 2 0 0 2 2 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SQS_PSY PF00494.14 EIE76508.1 - 2.2e-62 210.8 3.9 2.9e-62 210.4 2.7 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase Abhydrolase_6 PF12697.2 EIE76509.1 - 2.6e-38 132.1 0.0 3.4e-38 131.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIE76509.1 - 1.3e-21 77.2 0.0 5.2e-21 75.2 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIE76509.1 - 5e-18 65.2 0.0 6.6e-18 64.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EIE76509.1 - 6.4e-08 33.1 0.0 7.7e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.8 EIE76509.1 - 3e-07 30.2 0.0 4.7e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.3 EIE76509.1 - 1.2e-05 25.0 0.0 2.5e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Ndr PF03096.9 EIE76509.1 - 8.1e-05 21.2 0.0 0.00025 19.6 0.0 1.7 1 1 0 1 1 1 1 Ndr family Esterase PF00756.15 EIE76509.1 - 0.00063 19.2 0.0 0.00097 18.6 0.0 1.4 1 1 0 1 1 1 1 Putative esterase DUF676 PF05057.9 EIE76509.1 - 0.005 16.1 0.0 0.0084 15.4 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF3141 PF11339.3 EIE76509.1 - 0.08 11.2 0.0 0.099 10.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3141) DUF915 PF06028.6 EIE76509.1 - 0.14 11.1 0.1 7.6 5.5 0.2 2.3 1 1 1 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) zf-H2C2_2 PF13465.1 EIE76510.1 - 6.6e-13 48.2 8.4 1.3e-06 28.3 0.3 2.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 EIE76510.1 - 6e-11 42.0 11.1 8.6e-05 22.6 0.2 3.3 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIE76510.1 - 2.9e-07 30.3 8.3 0.03 14.6 0.2 3.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-TRAF PF02176.13 EIE76510.1 - 0.02 15.2 3.6 0.27 11.6 0.4 2.1 1 1 1 2 2 2 0 TRAF-type zinc finger zf-CGNR PF11706.3 EIE76510.1 - 0.34 10.4 1.8 0.94 9.0 0.3 2.2 2 0 0 2 2 2 0 CGNR zinc finger CYTL1 PF15153.1 EIE76511.1 - 0.00023 20.8 0.2 0.00073 19.2 0.0 1.8 2 1 0 2 2 2 1 Cytokine-like protein 1 ESSS PF10183.4 EIE76512.1 - 1.2e-16 60.9 0.0 1.5e-16 60.7 0.0 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) AIPR PF10592.4 EIE76513.1 - 0.0063 15.8 2.7 0.017 14.4 1.9 1.7 1 1 0 1 1 1 1 AIPR protein MRC1 PF09444.5 EIE76513.1 - 0.049 13.9 1.6 0.058 13.7 1.1 1.1 1 0 0 1 1 1 0 MRC1-like domain KAR9 PF08580.5 EIE76514.1 - 1.3e-05 23.7 17.9 4.8e-05 21.8 6.1 3.1 2 1 0 2 2 2 1 Yeast cortical protein KAR9 CoA_binding_2 PF13380.1 EIE76515.1 - 2.1e-32 111.7 0.0 2.5e-32 111.4 0.0 1.0 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.14 EIE76515.1 - 9.6e-07 29.2 0.0 1.4e-06 28.7 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain Glyco_hydro_38C PF07748.8 EIE76516.1 - 7.6e-88 295.3 0.0 1.1e-87 294.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Glyco_hydro_38 PF01074.17 EIE76516.1 - 1.2e-83 280.5 0.7 1.2e-83 280.5 0.5 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 N-terminal domain Alpha-mann_mid PF09261.6 EIE76516.1 - 5.1e-23 81.0 0.0 1.1e-22 80.0 0.0 1.6 1 0 0 1 1 1 1 Alpha mannosidase, middle domain Beach PF02138.13 EIE76517.1 - 0.045 13.1 0.1 0.062 12.7 0.1 1.2 1 0 0 1 1 1 0 Beige/BEACH domain Med11 PF10280.4 EIE76517.1 - 0.076 13.0 0.1 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Mediator complex protein DUF1917 PF08939.5 EIE76518.1 - 0.023 14.4 0.9 0.03 14.0 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1917) RR_TM4-6 PF06459.7 EIE76518.1 - 0.12 12.1 4.5 0.12 12.1 3.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Vfa1 PF08432.5 EIE76518.1 - 0.5 10.3 11.9 0.66 9.9 8.2 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 BTV_NS2 PF04514.7 EIE76518.1 - 0.77 8.5 9.4 0.93 8.3 6.5 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF1510 PF07423.6 EIE76518.1 - 1.9 7.8 9.2 2.3 7.5 6.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) NARP1 PF12569.3 EIE76518.1 - 2.4 6.8 11.1 2.9 6.5 7.7 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RNase_H2-Ydr279 PF09468.5 EIE76518.1 - 3.6 6.7 8.4 4.6 6.3 5.8 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Beach PF02138.13 EIE76520.1 - 0.045 13.1 0.1 0.062 12.7 0.1 1.2 1 0 0 1 1 1 0 Beige/BEACH domain Med11 PF10280.4 EIE76520.1 - 0.076 13.0 0.1 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Mediator complex protein AAA PF00004.24 EIE76521.1 - 7.4e-38 129.7 0.0 1.5e-37 128.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EIE76521.1 - 1.6e-07 31.5 0.5 0.00014 22.0 0.1 3.3 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.1 EIE76521.1 - 1.3e-06 28.3 0.0 3e-06 27.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EIE76521.1 - 2.6e-06 27.5 0.6 0.00012 22.1 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.7 EIE76521.1 - 2.9e-06 26.4 0.0 1.1e-05 24.5 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EIE76521.1 - 3.4e-06 26.8 0.1 1.8e-05 24.4 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EIE76521.1 - 2.5e-05 25.0 0.0 8.3e-05 23.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EIE76521.1 - 4.1e-05 23.5 0.0 8e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 EIE76521.1 - 4.3e-05 23.4 0.0 7.5e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EIE76521.1 - 0.00056 19.0 0.0 0.00098 18.2 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin Mg_chelatase PF01078.16 EIE76521.1 - 0.00056 19.1 0.2 0.0013 17.8 0.1 1.5 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 EIE76521.1 - 0.00057 19.3 0.0 0.001 18.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.17 EIE76521.1 - 0.00079 19.5 0.0 0.0017 18.4 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_25 PF13481.1 EIE76521.1 - 0.0008 18.8 0.4 0.032 13.6 0.2 2.2 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.1 EIE76521.1 - 0.0009 19.5 0.0 0.0021 18.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.1 EIE76521.1 - 0.0013 18.7 0.0 0.0033 17.4 0.0 1.7 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_28 PF13521.1 EIE76521.1 - 0.0016 18.4 0.0 0.0031 17.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain Bac_DnaA PF00308.13 EIE76521.1 - 0.0021 17.7 0.0 0.0041 16.7 0.0 1.4 1 0 0 1 1 1 1 Bacterial dnaA protein NACHT PF05729.7 EIE76521.1 - 0.0021 17.7 0.1 0.01 15.5 0.0 2.0 1 1 1 2 2 2 1 NACHT domain Guanylate_kin PF00625.16 EIE76521.1 - 0.0026 17.2 0.1 0.065 12.6 0.0 2.8 2 1 2 4 4 4 1 Guanylate kinase Rad17 PF03215.10 EIE76521.1 - 0.0033 16.1 0.0 0.0052 15.5 0.0 1.3 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein ABC_tran PF00005.22 EIE76521.1 - 0.0037 17.5 0.0 0.0092 16.2 0.0 1.9 1 1 0 1 1 1 1 ABC transporter TIP49 PF06068.8 EIE76521.1 - 0.0047 15.6 0.0 0.0081 14.9 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_24 PF13479.1 EIE76521.1 - 0.0057 16.2 0.3 0.012 15.2 0.2 1.6 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EIE76521.1 - 0.0095 15.6 0.0 0.026 14.2 0.0 1.8 1 1 0 1 1 1 1 Archaeal ATPase KaiC PF06745.8 EIE76521.1 - 0.0098 15.0 0.0 0.2 10.7 0.0 2.4 1 1 1 2 2 2 1 KaiC DUF815 PF05673.8 EIE76521.1 - 0.015 14.2 0.0 0.027 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Viral_helicase1 PF01443.13 EIE76521.1 - 0.016 14.7 0.0 0.028 13.9 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_10 PF12846.2 EIE76521.1 - 0.016 14.6 0.1 1.2 8.4 0.0 2.6 1 1 1 2 2 2 0 AAA-like domain UPF0079 PF02367.12 EIE76521.1 - 0.019 14.5 0.2 0.073 12.7 0.1 2.0 2 1 0 2 2 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_21 PF13304.1 EIE76521.1 - 0.025 14.5 0.3 7.7 6.3 0.0 2.9 2 1 1 3 3 3 0 AAA domain Sigma54_activat PF00158.21 EIE76521.1 - 0.027 13.9 0.0 0.06 12.8 0.0 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 EIE76521.1 - 0.03 13.1 0.0 0.049 12.4 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_19 PF13245.1 EIE76521.1 - 0.039 13.6 0.1 0.096 12.4 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain tRNA_lig_kinase PF08303.6 EIE76521.1 - 0.041 13.7 0.0 0.097 12.5 0.0 1.5 1 0 0 1 1 1 0 tRNA ligase kinase domain AAA_3 PF07726.6 EIE76521.1 - 0.043 13.4 0.0 0.12 12.0 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SKI PF01202.17 EIE76521.1 - 0.057 13.2 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Shikimate kinase NB-ARC PF00931.17 EIE76521.1 - 0.07 11.9 0.0 0.13 11.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain ATP-synt_ab PF00006.20 EIE76521.1 - 0.12 11.8 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain CPT PF07931.7 EIE76521.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein IDO PF01231.13 EIE76524.1 - 1.4e-123 412.5 0.0 1.6e-123 412.2 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF1864 PF08933.6 EIE76524.1 - 9.2e-06 24.4 0.0 1.9e-05 23.3 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF1864) Asp PF00026.18 EIE76525.1 - 1.4e-76 257.8 0.0 1.6e-76 257.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIE76525.1 - 2.4e-06 27.6 0.0 5.5e-06 26.4 0.0 1.6 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EIE76525.1 - 0.0046 16.5 0.0 0.01 15.3 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 EIE76525.1 - 0.032 14.7 0.0 11 6.5 0.0 2.6 2 1 0 2 2 2 0 Aspartyl protease Sugar_tr PF00083.19 EIE76526.1 - 2.1e-36 125.4 28.0 3.1e-34 118.3 19.4 2.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIE76526.1 - 1.5e-30 106.1 41.8 2.5e-30 105.3 28.9 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 EIE76526.1 - 0.11 12.3 6.3 0.16 11.7 0.2 2.8 2 0 0 2 2 2 0 MFS_1 like family F-box-like PF12937.2 EIE76527.1 - 0.00038 20.1 0.3 0.0013 18.4 0.2 2.0 1 0 0 1 1 1 1 F-box-like Asp PF00026.18 EIE76528.1 - 3e-88 296.1 3.4 4.4e-88 295.5 2.3 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIE76528.1 - 1.4e-08 34.8 1.3 1.1e-06 28.6 0.4 3.2 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EIE76528.1 - 9.1e-07 29.3 0.3 0.012 16.0 0.0 2.9 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 EIE76528.1 - 0.00062 19.3 0.1 0.058 12.9 0.1 2.6 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal 2-Hacid_dh PF00389.25 EIE76529.1 - 2.4e-15 56.1 0.0 2.8e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 2-Hacid_dh_C PF02826.14 EIE76529.1 - 1.9e-07 30.4 0.0 1e-06 28.0 0.1 1.8 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Dicty_CTDC PF00526.13 EIE76529.1 - 0.0087 15.8 0.0 0.022 14.6 0.0 1.7 1 0 0 1 1 1 1 Dictyostelium (slime mold) repeat Pmp3 PF01679.12 EIE76530.1 - 3.4e-25 87.4 4.8 3.7e-25 87.3 3.3 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator TM_helix PF05552.7 EIE76530.1 - 0.19 11.4 7.4 0.42 10.3 1.9 2.1 2 0 0 2 2 2 0 Conserved TM helix Frag1 PF10277.4 EIE76531.1 - 3e-37 128.1 16.6 4.1e-37 127.7 11.5 1.2 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Asp PF00026.18 EIE76532.1 - 3e-88 296.1 3.4 4.4e-88 295.5 2.3 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIE76532.1 - 1.4e-08 34.8 1.3 1.1e-06 28.6 0.4 3.2 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EIE76532.1 - 9.1e-07 29.3 0.3 0.012 16.0 0.0 2.9 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 EIE76532.1 - 0.00062 19.3 0.1 0.058 12.9 0.1 2.6 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Beta-APP PF03494.8 EIE76534.1 - 0.024 14.1 2.2 0.046 13.2 1.5 1.4 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) KAR9 PF08580.5 EIE76534.1 - 0.44 8.7 17.1 0.57 8.3 11.9 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 GFA PF04828.9 EIE76536.1 - 0.032 14.1 1.0 0.032 14.1 0.7 2.1 2 0 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zf-C4pol PF14260.1 EIE76536.1 - 0.23 11.4 4.1 2.2 8.3 2.6 2.3 1 1 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta DZR PF12773.2 EIE76536.1 - 0.33 10.7 7.9 5.6 6.8 5.5 2.3 1 1 0 1 1 1 0 Double zinc ribbon A2L_zn_ribbon PF08792.5 EIE76536.1 - 0.67 9.4 3.7 48 3.5 0.0 3.4 3 0 0 3 3 3 0 A2L zinc ribbon domain zf-ribbon_3 PF13248.1 EIE76536.1 - 3.7 6.8 6.2 3.4 7.0 1.8 2.4 1 1 1 2 2 2 0 zinc-ribbon domain HypA PF01155.14 EIE76536.1 - 6.6 6.4 6.2 12 5.6 1.2 2.5 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Helitron_like_N PF14214.1 EIE76537.1 - 5.5e-33 114.2 0.1 1.8e-32 112.5 0.0 1.9 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.9 EIE76537.1 - 1.3e-28 100.0 0.0 2e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 EIE76537.1 - 2.2e-05 24.1 0.0 3.3e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EIE76537.1 - 0.00025 20.7 0.0 0.00049 19.7 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain ResIII PF04851.10 EIE76537.1 - 0.0003 20.6 0.0 0.00061 19.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_5 PF07728.9 EIE76537.1 - 0.0054 16.4 0.0 0.014 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EIE76537.1 - 0.016 15.2 0.0 0.093 12.7 0.0 2.3 3 0 0 3 3 2 0 AAA ATPase domain TrwB_AAD_bind PF10412.4 EIE76537.1 - 0.019 13.6 0.0 0.031 12.8 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain T2SE PF00437.15 EIE76537.1 - 0.021 13.7 0.0 0.04 12.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.11 EIE76537.1 - 0.034 13.3 0.0 0.054 12.7 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein DAP3 PF10236.4 EIE76537.1 - 0.043 12.7 0.0 0.078 11.8 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_22 PF13401.1 EIE76537.1 - 0.093 12.8 0.0 0.52 10.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EIE76537.1 - 0.13 11.6 0.0 0.72 9.2 0.0 2.1 2 1 1 3 3 3 0 AAA-like domain Sigma54_activat PF00158.21 EIE76537.1 - 0.18 11.2 0.0 0.31 10.4 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain PIF1 PF05970.9 EIE76538.1 - 1.3e-16 60.5 0.2 1.4e-16 60.3 0.1 1.0 1 0 0 1 1 1 1 PIF1-like helicase PIF1 PF05970.9 EIE76539.1 - 4.6e-16 58.7 0.2 5.7e-16 58.4 0.1 1.1 1 0 0 1 1 1 1 PIF1-like helicase Herpes_Helicase PF02689.9 EIE76539.1 - 0.00079 17.3 0.0 0.00095 17.0 0.0 1.0 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.1 EIE76539.1 - 0.0086 16.2 0.0 0.014 15.5 0.0 1.5 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain PIF1 PF05970.9 EIE76540.1 - 9.4e-29 100.4 0.0 1.5e-28 99.8 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 EIE76540.1 - 1.6e-05 24.5 0.0 2.5e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EIE76540.1 - 0.00018 21.1 0.0 0.00037 20.1 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain ResIII PF04851.10 EIE76540.1 - 0.00024 20.9 0.0 0.00046 20.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_5 PF07728.9 EIE76540.1 - 0.0043 16.7 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) TrwB_AAD_bind PF10412.4 EIE76540.1 - 0.014 14.0 0.0 0.024 13.2 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain T2SE PF00437.15 EIE76540.1 - 0.015 14.2 0.0 0.029 13.2 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.1 EIE76540.1 - 0.02 14.8 0.0 0.071 13.0 0.0 1.9 3 0 0 3 3 3 0 AAA ATPase domain PhoH PF02562.11 EIE76540.1 - 0.026 13.7 0.0 0.041 13.1 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein DAP3 PF10236.4 EIE76540.1 - 0.031 13.2 0.0 0.062 12.2 0.0 1.5 1 1 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_22 PF13401.1 EIE76540.1 - 0.07 13.2 0.0 0.39 10.8 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EIE76540.1 - 0.081 12.3 0.0 0.56 9.5 0.0 2.1 2 1 1 3 3 3 0 AAA-like domain Sigma54_activat PF00158.21 EIE76540.1 - 0.15 11.5 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain GFA PF04828.9 EIE76541.1 - 0.032 14.1 1.0 0.032 14.1 0.7 2.1 2 0 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zf-C4pol PF14260.1 EIE76541.1 - 0.23 11.4 4.1 2.2 8.3 2.6 2.3 1 1 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta DZR PF12773.2 EIE76541.1 - 0.33 10.7 7.9 5.6 6.8 5.5 2.3 1 1 0 1 1 1 0 Double zinc ribbon A2L_zn_ribbon PF08792.5 EIE76541.1 - 0.67 9.4 3.7 48 3.5 0.0 3.4 3 0 0 3 3 3 0 A2L zinc ribbon domain zf-ribbon_3 PF13248.1 EIE76541.1 - 3.7 6.8 6.2 3.4 7.0 1.8 2.4 1 1 1 2 2 2 0 zinc-ribbon domain HypA PF01155.14 EIE76541.1 - 6.6 6.4 6.2 12 5.6 1.2 2.5 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Beta-APP PF03494.8 EIE76543.1 - 0.024 14.1 2.2 0.046 13.2 1.5 1.4 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) KAR9 PF08580.5 EIE76543.1 - 0.44 8.7 17.1 0.57 8.3 11.9 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Sld5 PF05916.6 EIE76544.1 - 0.016 15.4 1.6 0.021 15.1 1.1 1.5 1 1 0 1 1 1 0 GINS complex protein DUF148 PF02520.12 EIE76544.1 - 0.055 13.2 0.1 0.073 12.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF148 Ras PF00071.17 EIE76545.1 - 7.1e-61 204.3 0.3 8.5e-61 204.0 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIE76545.1 - 1.6e-20 73.7 0.0 2.5e-20 73.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIE76545.1 - 3.3e-13 49.2 0.1 4.9e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EIE76545.1 - 3.5e-06 26.5 0.1 6.6e-06 25.6 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EIE76545.1 - 9.8e-06 25.5 0.1 1.7e-05 24.7 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EIE76545.1 - 2.5e-05 23.5 0.0 3.4e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_15 PF13175.1 EIE76545.1 - 0.00074 18.6 0.0 0.00092 18.3 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 EIE76545.1 - 0.00089 18.4 0.5 0.0073 15.5 0.1 2.1 2 1 0 2 2 2 1 Protein of unknown function, DUF258 KAP_NTPase PF07693.9 EIE76545.1 - 0.0033 16.4 0.0 0.0044 16.0 0.0 1.1 1 0 0 1 1 1 1 KAP family P-loop domain AAA_22 PF13401.1 EIE76545.1 - 0.0053 16.8 0.0 0.012 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EIE76545.1 - 0.0079 16.0 0.1 0.024 14.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EIE76545.1 - 0.033 14.4 0.3 0.059 13.6 0.2 1.7 1 1 0 1 1 1 0 ABC transporter SRPRB PF09439.5 EIE76545.1 - 0.04 13.1 0.0 0.089 12.0 0.0 1.6 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 EIE76545.1 - 0.052 12.8 0.1 0.61 9.3 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_16 PF13191.1 EIE76545.1 - 0.08 12.9 0.3 0.21 11.5 0.2 2.0 1 1 0 1 1 1 0 AAA ATPase domain Septin PF00735.13 EIE76545.1 - 0.095 11.6 0.1 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_29 PF13555.1 EIE76545.1 - 0.11 12.0 0.0 0.41 10.2 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain MULE PF10551.4 EIE76546.1 - 4.3e-06 26.8 0.0 9.7e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 EIE76546.1 - 8.6e-06 24.5 1.5 1.7e-05 23.5 1.0 1.5 1 0 0 1 1 1 1 Transposase, Mutator family Pkinase PF00069.20 EIE76548.1 - 1.3e-44 152.3 0.5 1.9e-26 92.7 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIE76548.1 - 8.5e-28 97.1 0.7 9.5e-17 60.9 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EIE76548.1 - 0.00068 18.6 0.0 0.057 12.3 0.0 2.2 1 1 1 2 2 2 2 Kinase-like Proteasom_PSMB PF10508.4 EIE76548.1 - 0.017 13.4 0.0 0.91 7.7 0.0 2.2 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit NusB PF01029.13 EIE76548.1 - 0.079 12.9 0.0 2.4 8.1 0.0 2.9 3 0 0 3 3 3 0 NusB family DDE_2 PF02914.10 EIE76548.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage Mu transposase Ribosomal_L5_C PF00673.16 EIE76549.1 - 5e-25 87.0 0.0 8.5e-25 86.3 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 EIE76549.1 - 2.3e-07 30.4 0.0 4.3e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L5 6PF2K PF01591.13 EIE76550.1 - 7.8e-55 185.3 3.2 2.1e-53 180.7 0.3 2.5 2 1 0 2 2 2 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EIE76550.1 - 4.2e-22 78.9 3.5 7.7e-22 78.0 1.9 1.9 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EIE76550.1 - 3.9e-05 23.5 0.0 8.9e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain DAGK_acc PF00609.14 EIE76550.1 - 0.067 13.3 0.0 2.1 8.4 0.0 2.3 2 0 0 2 2 2 0 Diacylglycerol kinase accessory domain RRM_1 PF00076.17 EIE76551.1 - 2.2e-10 40.0 0.1 4e-10 39.1 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE76551.1 - 3.7e-06 26.8 0.1 6.6e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE76551.1 - 8.5e-06 25.5 0.1 1.8e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.19 EIE76551.1 - 0.0006 19.4 1.4 0.0006 19.4 1.0 2.2 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_3 PF08777.6 EIE76551.1 - 0.0026 17.5 0.1 0.005 16.6 0.1 1.4 1 0 0 1 1 1 1 RNA binding motif Nup35_RRM_2 PF14605.1 EIE76551.1 - 0.029 14.1 0.0 0.059 13.1 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif zf-CCCH_2 PF14608.1 EIE76551.1 - 0.23 11.5 3.3 0.63 10.1 2.3 1.7 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type MRP-S28 PF10213.4 EIE76552.1 - 1.7e-19 70.1 0.1 4.8e-19 68.6 0.0 1.6 2 0 0 2 2 2 1 Mitochondrial ribosomal subunit protein DUF221 PF02714.10 EIE76553.1 - 3.8e-80 269.1 23.9 6.8e-80 268.3 16.6 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EIE76553.1 - 6e-18 64.8 6.6 3.8e-16 59.0 0.0 3.8 3 1 0 3 3 3 2 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EIE76553.1 - 1.1e-14 54.6 0.0 2.9e-14 53.3 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) Syndecan PF01034.15 EIE76553.1 - 0.077 12.6 0.0 0.27 10.8 0.0 2.0 1 0 0 1 1 1 0 Syndecan domain Abhydrolase_2 PF02230.11 EIE76554.1 - 1e-42 146.0 0.0 3.2e-34 118.2 0.0 2.0 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EIE76554.1 - 1.9e-12 47.1 0.0 2.3e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIE76554.1 - 9e-08 32.2 0.1 0.0028 17.5 0.1 2.3 1 1 1 2 2 2 2 Alpha/beta hydrolase family DLH PF01738.13 EIE76554.1 - 2.7e-07 30.1 0.0 4e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.16 EIE76554.1 - 1.4e-06 27.7 0.2 3.8e-05 23.0 0.0 2.1 1 1 1 2 2 2 1 Prolyl oligopeptidase family FSH1 PF03959.8 EIE76554.1 - 6.3e-06 25.7 0.0 0.0003 20.2 0.0 2.1 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.8 EIE76554.1 - 1.1e-05 25.1 0.0 0.00046 19.8 0.0 2.0 1 1 1 2 2 2 2 alpha/beta hydrolase fold Esterase_phd PF10503.4 EIE76554.1 - 0.0023 17.2 0.0 0.078 12.2 0.0 2.4 2 1 1 3 3 3 1 Esterase PHB depolymerase Abhydrolase_1 PF00561.15 EIE76554.1 - 0.0093 15.5 0.3 3.2 7.2 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 EIE76554.1 - 0.086 12.7 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein Abhydrolase_2 PF02230.11 EIE76555.1 - 1.6e-38 132.3 0.0 1.7e-31 109.3 0.0 2.0 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EIE76555.1 - 1.2e-13 51.0 0.0 1.5e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EIE76555.1 - 2.8e-08 33.2 0.7 2.7e-06 26.7 0.0 2.1 1 1 1 2 2 2 2 Prolyl oligopeptidase family FSH1 PF03959.8 EIE76555.1 - 1.7e-07 30.8 0.0 6.1e-06 25.8 0.1 2.1 1 1 1 2 2 2 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EIE76555.1 - 2.3e-07 30.9 0.3 0.014 15.2 0.1 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family DLH PF01738.13 EIE76555.1 - 9.3e-07 28.3 0.0 1.4e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.8 EIE76555.1 - 3.5e-05 23.4 0.0 0.0015 18.1 0.0 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold BAAT_C PF08840.6 EIE76555.1 - 0.0003 20.5 0.3 0.059 13.0 0.0 2.1 1 1 1 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_4 PF08386.5 EIE76555.1 - 0.019 14.8 0.0 0.028 14.3 0.0 1.2 1 0 0 1 1 1 0 TAP-like protein Abhydrolase_1 PF00561.15 EIE76555.1 - 0.021 14.3 0.3 5.2 6.5 0.1 2.2 1 1 1 2 2 2 0 alpha/beta hydrolase fold Esterase PF00756.15 EIE76555.1 - 0.021 14.2 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Cutinase PF01083.17 EIE76555.1 - 0.082 12.6 0.1 0.41 10.3 0.0 2.0 2 0 0 2 2 2 0 Cutinase DUF2235 PF09994.4 EIE76555.1 - 0.099 11.9 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) E1-E2_ATPase PF00122.15 EIE76557.1 - 3.6e-61 206.1 2.8 3.6e-61 206.1 2.0 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EIE76557.1 - 5.2e-41 140.1 8.6 5.2e-41 140.1 6.0 2.5 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EIE76557.1 - 2.1e-27 96.9 0.1 4.1e-27 96.0 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EIE76557.1 - 2e-16 60.7 0.0 7.1e-16 58.9 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EIE76557.1 - 1e-15 57.4 0.0 2.6e-15 56.1 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EIE76557.1 - 6.2e-07 28.7 0.0 6.3e-06 25.5 0.0 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EIE76557.1 - 3.4e-05 23.5 0.5 6.4e-05 22.6 0.4 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase NIF PF03031.13 EIE76558.1 - 6.7e-17 61.6 0.0 1.1e-16 60.9 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase UMPH-1 PF05822.7 EIE76560.1 - 3.2e-53 180.5 2.6 3.5e-53 180.4 1.8 1.0 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) DUF2333 PF10095.4 EIE76561.1 - 0.012 14.2 0.2 0.056 12.0 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2333) GST_C_3 PF14497.1 EIE76562.1 - 4.5e-08 33.4 0.2 1.2e-07 32.1 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EIE76562.1 - 2.3e-06 27.4 1.3 4.9e-06 26.4 0.1 2.0 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EIE76562.1 - 5.3e-05 23.0 0.0 0.00011 21.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EIE76562.1 - 8.4e-05 22.6 0.2 0.00063 19.8 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain RLL PF10036.4 EIE76562.1 - 0.006 16.0 0.1 0.099 12.0 0.1 2.0 2 0 0 2 2 2 1 Putative carnitine deficiency-associated protein DUF3712 PF12505.3 EIE76563.1 - 2.7e-71 237.4 35.6 5.5e-22 78.1 0.8 6.5 6 0 0 6 6 6 4 Protein of unknown function (DUF3712) LEA_2 PF03168.8 EIE76563.1 - 1.2e-07 32.0 26.6 0.39 11.1 0.0 9.1 10 0 0 10 10 10 5 Late embryogenesis abundant protein Sigma_reg_N PF13800.1 EIE76563.1 - 0.0098 15.9 2.1 0.023 14.7 0.5 2.4 2 0 0 2 2 2 1 Sigma factor regulator N-terminal DUF2304 PF10066.4 EIE76563.1 - 0.049 13.4 2.1 0.12 12.2 1.4 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) Chordopox_A13L PF05961.6 EIE76563.1 - 0.16 11.9 7.2 0.38 10.7 5.0 1.6 1 0 0 1 1 1 0 Chordopoxvirus A13L protein DUF3827 PF12877.2 EIE76563.1 - 0.44 8.5 8.7 0.1 10.6 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3827) Baculo_11_kDa PF06143.6 EIE76563.1 - 1 8.7 4.8 2.3 7.6 3.4 1.5 1 0 0 1 1 1 0 Baculovirus 11 kDa family Vac7 PF12751.2 EIE76564.1 - 1.2e-11 44.0 8.3 1.9e-08 33.5 0.5 2.6 1 1 1 2 2 2 2 Vacuolar segregation subunit 7 Fijivirus_P9-2 PF06837.6 EIE76565.1 - 0.076 12.1 1.7 0.16 11.1 1.2 1.4 1 0 0 1 1 1 0 Fijivirus P9-2 protein LIM PF00412.17 EIE76567.1 - 2.9e-50 168.1 49.7 1.1e-15 57.4 4.8 4.3 4 0 0 4 4 4 4 LIM domain C1_3 PF07649.7 EIE76567.1 - 0.62 10.1 0.1 0.62 10.1 0.1 7.7 8 1 1 9 9 9 0 C1-like domain AAA_11 PF13086.1 EIE76568.1 - 7.2e-63 212.3 1.3 7.2e-63 212.3 0.9 2.1 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 EIE76568.1 - 3.1e-62 209.5 0.0 9.3e-62 207.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain SEN1_N PF12726.2 EIE76568.1 - 1.2e-23 83.0 4.6 6e-17 60.9 1.4 2.3 1 1 1 2 2 2 2 SEN1 N terminal AAA_19 PF13245.1 EIE76568.1 - 3.8e-15 55.4 0.0 1.2e-14 53.7 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EIE76568.1 - 2.3e-11 43.6 0.3 8.7e-09 35.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain UvrD-helicase PF00580.16 EIE76568.1 - 5.2e-09 35.8 3.8 2.9e-07 30.1 0.0 3.0 2 1 1 3 3 3 2 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.9 EIE76568.1 - 2.1e-05 24.2 0.1 0.0011 18.6 0.0 2.6 2 0 0 2 2 2 1 Helicase ResIII PF04851.10 EIE76568.1 - 5.6e-05 23.0 0.1 0.00037 20.3 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EIE76568.1 - 0.00014 21.4 0.8 0.00099 18.6 0.5 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_16 PF13191.1 EIE76568.1 - 0.0083 16.1 0.4 0.056 13.4 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 EIE76568.1 - 0.01 16.0 0.4 0.068 13.3 0.1 2.6 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 EIE76568.1 - 0.013 14.6 0.1 0.042 13.0 0.0 1.8 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.1 EIE76568.1 - 0.031 13.6 0.0 0.067 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF3305 PF11749.3 EIE76568.1 - 0.051 13.4 0.1 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3305) AAA_22 PF13401.1 EIE76568.1 - 0.07 13.2 0.0 0.48 10.5 0.0 2.5 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.9 EIE76571.1 - 1.1e-44 152.3 0.0 1.6e-44 151.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 EIE76571.1 - 4.4e-16 59.2 0.0 8.6e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 EIE76571.1 - 2.2e-08 33.8 0.1 5.2e-08 32.6 0.1 1.6 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 EIE76571.1 - 7.2e-08 32.2 0.0 2.1e-07 30.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EIE76571.1 - 5.6e-06 25.6 0.1 0.0007 18.8 0.0 2.3 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 EIE76571.1 - 7.8e-06 25.4 0.0 0.0064 15.9 0.0 2.6 3 0 0 3 3 2 1 Sigma-54 interaction domain AAA_22 PF13401.1 EIE76571.1 - 8.1e-06 26.0 0.2 0.00049 20.2 0.2 2.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EIE76571.1 - 8.2e-05 22.6 0.4 0.00029 20.8 0.3 1.9 1 1 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.12 EIE76571.1 - 8.3e-05 22.0 0.0 0.00015 21.2 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_17 PF13207.1 EIE76571.1 - 9.6e-05 23.1 0.0 0.00032 21.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EIE76571.1 - 0.00018 21.4 0.0 0.00069 19.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 EIE76571.1 - 0.00022 21.2 0.0 0.0006 19.8 0.0 1.8 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_33 PF13671.1 EIE76571.1 - 0.00072 19.4 0.0 0.0017 18.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EIE76571.1 - 0.00084 18.4 0.1 0.0024 16.9 0.1 1.6 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus T2SE PF00437.15 EIE76571.1 - 0.001 18.0 0.0 0.0017 17.2 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.22 EIE76571.1 - 0.002 18.4 0.0 0.0043 17.3 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_24 PF13479.1 EIE76571.1 - 0.0027 17.3 0.0 0.0049 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EIE76571.1 - 0.0031 17.0 0.0 0.007 15.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain NACHT PF05729.7 EIE76571.1 - 0.0065 16.1 0.0 0.026 14.1 0.0 1.9 2 0 0 2 2 2 1 NACHT domain DEAD PF00270.24 EIE76571.1 - 0.01 15.3 0.3 0.079 12.4 0.0 2.2 1 1 0 2 2 2 0 DEAD/DEAH box helicase PhoH PF02562.11 EIE76571.1 - 0.011 14.9 0.0 0.021 14.0 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_19 PF13245.1 EIE76571.1 - 0.014 15.1 0.0 0.031 14.0 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain ResIII PF04851.10 EIE76571.1 - 0.017 14.9 1.0 0.094 12.5 0.2 2.4 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_18 PF13238.1 EIE76571.1 - 0.02 15.2 0.0 0.055 13.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain MCM PF00493.18 EIE76571.1 - 0.02 13.7 0.2 0.068 11.9 0.1 1.8 1 1 0 1 1 1 0 MCM2/3/5 family Glyco_trans_4_2 PF13477.1 EIE76571.1 - 0.023 14.5 0.0 0.04 13.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase 4-like AAA_23 PF13476.1 EIE76571.1 - 0.029 14.6 0.1 0.072 13.4 0.0 1.7 2 1 0 2 2 1 0 AAA domain UPF0079 PF02367.12 EIE76571.1 - 0.034 13.7 0.0 0.073 12.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 TIP49 PF06068.8 EIE76571.1 - 0.047 12.3 0.0 0.075 11.7 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus FtsK_SpoIIIE PF01580.13 EIE76571.1 - 0.049 13.1 0.0 0.086 12.3 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_3 PF07726.6 EIE76571.1 - 0.061 12.9 0.0 0.13 11.8 0.0 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SRPRB PF09439.5 EIE76571.1 - 0.064 12.4 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit RNA_helicase PF00910.17 EIE76571.1 - 0.088 12.9 0.0 0.23 11.6 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_28 PF13521.1 EIE76571.1 - 0.09 12.7 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 EIE76571.1 - 0.099 12.1 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation SWIB PF02201.13 EIE76572.1 - 1e-19 69.9 0.6 4.2e-19 68.0 0.0 2.4 3 0 0 3 3 3 1 SWIB/MDM2 domain Nop53 PF07767.6 EIE76572.1 - 0.01 14.8 2.0 0.016 14.2 1.4 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Asp PF00026.18 EIE76574.1 - 7e-14 51.7 0.7 1.3e-13 50.9 0.5 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Band_7 PF01145.20 EIE76576.1 - 7.2e-25 87.9 3.9 8.2e-25 87.7 2.2 1.4 1 1 0 1 1 1 1 SPFH domain / Band 7 family DUF2884 PF11101.3 EIE76576.1 - 0.022 14.1 1.1 0.034 13.5 0.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2884) DUF3811 PF11656.3 EIE76576.1 - 0.38 10.8 2.9 0.71 9.9 1.8 1.7 1 1 0 1 1 1 0 YjbD family (DUF3811) Asp PF00026.18 EIE76578.1 - 1.1e-68 231.8 0.0 1.3e-68 231.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIE76578.1 - 4.5e-10 39.7 0.1 1e-08 35.2 0.1 2.9 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EIE76578.1 - 4.3e-06 26.3 0.1 2e-05 24.2 0.0 2.1 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 EIE76578.1 - 0.0069 16.8 0.5 0.28 11.6 0.0 2.6 2 1 0 2 2 2 1 Aspartyl protease ADH_N PF08240.7 EIE76579.1 - 7.5e-25 86.8 7.3 1.3e-24 86.0 5.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIE76579.1 - 1.4e-20 73.1 0.0 2.1e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EIE76579.1 - 0.00019 20.6 0.0 0.00032 19.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DHBP_synthase PF00926.14 EIE76580.1 - 8.2e-81 269.8 0.4 9.3e-81 269.6 0.3 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase ATP-synt_ab PF00006.20 EIE76581.1 - 8.8e-64 214.9 0.0 1.9e-63 213.8 0.0 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.18 EIE76581.1 - 4.2e-25 87.7 2.6 8.4e-25 86.7 1.4 1.9 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain ATP-synt_ab_C PF00306.22 EIE76581.1 - 4.9e-24 84.9 1.3 8.4e-24 84.2 0.9 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain MobB PF03205.9 EIE76581.1 - 0.0025 17.5 0.1 0.96 9.1 0.0 3.1 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 EIE76581.1 - 0.0038 16.9 0.0 0.0078 15.9 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase AAA_22 PF13401.1 EIE76581.1 - 0.006 16.7 0.0 0.12 12.5 0.0 2.5 2 1 0 2 2 2 1 AAA domain NACHT PF05729.7 EIE76581.1 - 0.0066 16.1 0.1 0.016 14.8 0.0 1.7 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 EIE76581.1 - 0.017 15.1 0.9 0.047 13.6 0.0 2.2 3 0 0 3 3 3 0 AAA ATPase domain NB-ARC PF00931.17 EIE76581.1 - 0.02 13.7 1.0 0.034 13.0 0.1 1.7 2 0 0 2 2 2 0 NB-ARC domain AAA PF00004.24 EIE76581.1 - 0.04 14.1 0.1 0.52 10.5 0.0 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) KaiC PF06745.8 EIE76581.1 - 0.04 13.0 0.1 0.083 11.9 0.1 1.6 1 0 0 1 1 1 0 KaiC AAA_25 PF13481.1 EIE76581.1 - 0.043 13.2 0.1 0.16 11.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 EIE76581.1 - 0.062 12.4 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 RNA_helicase PF00910.17 EIE76581.1 - 0.12 12.5 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase CAF-1_p150 PF11600.3 EIE76582.1 - 3.7 6.8 8.3 8.1 5.7 5.3 1.9 1 1 1 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal RCC1 PF00415.13 EIE76584.1 - 1.7e-26 92.1 0.1 4.5e-07 29.9 0.0 4.3 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat Ank_4 PF13637.1 EIE76584.1 - 1.2e-19 70.2 1.2 8.1e-14 51.6 0.2 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 EIE76584.1 - 4.3e-15 54.6 0.0 3.3e-06 26.6 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 EIE76584.1 - 5e-13 49.1 0.6 1.4e-12 47.8 0.4 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) RCC1_2 PF13540.1 EIE76584.1 - 1.3e-11 43.7 2.0 1.1e-07 31.2 0.0 3.4 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat Ank_3 PF13606.1 EIE76584.1 - 2.9e-11 42.4 0.2 7.6e-05 22.5 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 EIE76584.1 - 6.6e-10 38.9 1.0 1.5e-05 25.0 0.3 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) BTB PF00651.26 EIE76585.1 - 2.3e-20 72.6 7.8 2.7e-10 40.2 0.4 3.8 3 1 1 4 4 4 2 BTB/POZ domain Phage_integrase PF00589.17 EIE76585.1 - 0.14 11.8 2.2 0.11 12.1 0.3 1.7 2 0 0 2 2 2 0 Phage integrase family GIY-YIG PF01541.19 EIE76586.1 - 0.62 10.4 4.6 18 5.7 0.8 3.2 1 1 1 2 2 2 0 GIY-YIG catalytic domain AAA_12 PF13087.1 EIE76587.1 - 4.6e-43 146.9 0.0 8.2e-43 146.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EIE76587.1 - 2.5e-28 99.2 0.7 1.6e-26 93.3 0.5 2.4 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EIE76587.1 - 2e-06 27.5 0.0 0.0023 17.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EIE76587.1 - 3.4e-06 26.6 0.0 7.7e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain DUF2075 PF09848.4 EIE76587.1 - 0.00078 18.5 0.2 0.016 14.2 0.0 2.7 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.16 EIE76587.1 - 0.0016 17.7 1.4 0.02 14.2 0.7 2.7 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain ResIII PF04851.10 EIE76587.1 - 0.0026 17.6 0.1 0.017 14.9 0.0 2.2 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 EIE76587.1 - 0.003 17.1 0.0 0.76 9.2 0.0 3.3 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase PhoH PF02562.11 EIE76587.1 - 0.015 14.5 0.1 0.14 11.3 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA_22 PF13401.1 EIE76587.1 - 0.016 15.3 0.2 1.9 8.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain Pyr_redox_dim PF02852.17 EIE76588.1 - 4.2e-32 110.4 0.4 7.3e-32 109.6 0.3 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 EIE76588.1 - 7.5e-30 104.3 0.0 1.5e-28 100.0 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EIE76588.1 - 5.3e-17 61.9 2.6 5.9e-17 61.8 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EIE76588.1 - 3.2e-09 37.1 0.6 2.3e-06 27.8 0.0 3.1 1 1 2 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EIE76588.1 - 7e-06 25.1 0.0 9.5e-05 21.4 0.0 2.3 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) UDPG_MGDP_dh_N PF03721.9 EIE76588.1 - 0.00045 19.6 0.0 0.00074 18.9 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.14 EIE76588.1 - 0.00047 19.3 0.1 0.0016 17.6 0.0 1.9 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.9 EIE76588.1 - 0.0005 18.6 0.9 1.7 6.9 0.0 3.8 3 1 1 4 4 4 1 HI0933-like protein 3HCDH_N PF02737.13 EIE76588.1 - 0.00063 19.4 0.0 0.0016 18.0 0.0 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EIE76588.1 - 0.0014 18.2 1.3 0.0063 16.0 0.0 2.5 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_Gly3P_dh_N PF01210.18 EIE76588.1 - 0.039 13.6 0.6 0.17 11.6 0.0 2.1 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.10 EIE76588.1 - 0.12 12.2 0.1 0.31 10.8 0.0 1.9 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase DAO PF01266.19 EIE76588.1 - 0.14 11.0 2.7 11 4.8 0.1 3.4 4 0 0 4 4 4 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EIE76588.1 - 0.2 10.4 3.6 12 4.5 1.3 3.0 3 0 0 3 3 3 0 FAD binding domain RVT_1 PF00078.22 EIE76590.1 - 4.6e-20 71.9 0.1 1.2e-19 70.5 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) MFS_1 PF07690.11 EIE76591.1 - 1.6e-32 112.6 59.3 5e-26 91.2 19.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIE76591.1 - 1.5e-07 30.3 25.7 7.4e-05 21.4 3.1 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.2 EIE76591.1 - 0.022 14.5 0.3 0.022 14.5 0.2 2.4 3 0 0 3 3 3 0 MFS_1 like family SET PF00856.23 EIE76594.1 - 9.3e-28 97.5 2.5 6.7e-27 94.7 1.7 2.1 1 1 0 1 1 1 1 SET domain Chs3p PF12271.3 EIE76595.1 - 1.3e-98 329.6 25.1 1.5e-98 329.3 17.4 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit Usp PF00582.21 EIE76596.1 - 2.1e-27 96.0 0.1 6.4e-27 94.4 0.1 1.6 1 1 0 1 1 1 1 Universal stress protein family DUF3375 PF11855.3 EIE76596.1 - 0.05 12.3 0.7 0.066 11.9 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3375) CorA PF01544.13 EIE76597.1 - 0.021 13.8 0.5 0.029 13.4 0.4 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DDE_1 PF03184.14 EIE76598.1 - 1.3e-28 99.6 0.0 1.7e-28 99.2 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EIE76598.1 - 0.00022 20.9 0.0 0.00031 20.5 0.0 1.3 1 1 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE76599.1 - 4.7e-19 68.6 0.0 1.1e-18 67.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE76599.1 - 6.9e-17 61.5 0.9 1.3e-16 60.6 0.2 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE76599.1 - 4.1e-14 51.9 1.1 1.2e-13 50.4 0.7 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.1 EIE76599.1 - 5.1e-05 23.7 0.0 0.00012 22.4 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 EIE76599.1 - 9.8e-05 22.2 0.2 0.00035 20.4 0.1 2.0 1 0 0 1 1 1 1 Retroviral aspartyl protease F_actin_bind PF08919.5 EIE76599.1 - 0.015 14.9 0.0 0.12 12.0 0.0 2.6 1 0 0 1 1 1 0 F-actin binding Exo_endo_phos_2 PF14529.1 EIE76600.1 - 5e-06 26.1 0.4 7.5e-06 25.5 0.2 1.4 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EIE76600.1 - 0.00095 19.1 0.8 0.001 19.0 0.6 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DDE_3 PF13358.1 EIE76601.1 - 5.7e-17 61.8 0.0 8.1e-17 61.3 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE76601.1 - 9.1e-10 38.4 2.5 4.8e-09 36.1 0.9 2.3 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.1 EIE76601.1 - 0.00049 19.6 0.0 0.0012 18.4 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_11 PF08279.7 EIE76601.1 - 0.00065 19.2 0.0 0.0018 17.8 0.0 1.7 1 0 0 1 1 1 1 HTH domain HTH_IclR PF09339.5 EIE76601.1 - 0.00073 19.0 0.0 0.0014 18.1 0.0 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_7 PF02796.10 EIE76601.1 - 0.0026 17.6 0.3 0.058 13.2 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_32 PF13565.1 EIE76601.1 - 0.0041 17.8 0.8 3 8.6 0.0 2.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_38 PF13936.1 EIE76601.1 - 0.0066 15.9 0.0 0.016 14.7 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_36 PF13730.1 EIE76601.1 - 0.0074 16.3 0.4 0.24 11.5 0.0 2.9 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_AsnC-type PF13404.1 EIE76601.1 - 0.014 14.9 0.0 0.031 13.8 0.0 1.5 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Sigma70_r4_2 PF08281.7 EIE76601.1 - 0.015 14.7 0.0 0.029 13.8 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_Tnp_4 PF13613.1 EIE76601.1 - 0.017 14.6 0.0 0.29 10.7 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix of DDE superfamily endonuclease HTH_29 PF13551.1 EIE76601.1 - 0.026 14.6 0.1 0.17 12.0 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn helix UPF0122 PF04297.9 EIE76601.1 - 0.036 14.0 0.3 0.1 12.6 0.0 1.7 2 0 0 2 2 2 0 Putative helix-turn-helix protein, YlxM / p13 like HTH_24 PF13412.1 EIE76601.1 - 0.039 13.3 0.0 0.091 12.1 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_17 PF12728.2 EIE76601.1 - 0.04 14.1 0.0 0.089 13.0 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4 PF04545.11 EIE76601.1 - 0.045 13.0 0.0 0.082 12.2 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 GerE PF00196.14 EIE76601.1 - 0.092 12.0 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family DDE_3 PF13358.1 EIE76603.1 - 5.9e-12 45.5 0.1 3.5e-06 26.8 0.5 2.2 1 1 1 2 2 2 2 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE76603.1 - 0.00028 20.8 0.9 0.00043 20.2 0.6 1.3 1 0 0 1 1 1 1 Transposase DUF1033 PF06279.6 EIE76603.1 - 0.025 14.3 0.7 0.025 14.3 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1033) Lzipper-MIP1 PF14389.1 EIE76604.1 - 0.0044 17.1 0.4 0.012 15.6 0.3 1.8 1 0 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 IncA PF04156.9 EIE76604.1 - 0.14 11.7 1.2 0.24 10.9 0.8 1.4 1 0 0 1 1 1 0 IncA protein DUF4404 PF14357.1 EIE76604.1 - 0.17 12.3 1.9 5.2 7.5 0.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) SRR PF07709.6 EIE76604.1 - 0.18 12.0 4.4 5.1 7.7 0.0 3.6 3 0 0 3 3 3 0 Seven Residue Repeat ChaB PF06150.7 EIE76604.1 - 0.23 11.3 0.2 0.23 11.3 0.1 2.2 3 0 0 3 3 3 0 ChaB Transposase_21 PF02992.9 EIE76605.1 - 5.3e-23 81.3 0.1 5.3e-23 81.3 0.1 1.6 2 0 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.1 EIE76605.1 - 3.8e-05 23.1 0.3 8.4e-05 22.0 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) DDE_3 PF13358.1 EIE76606.1 - 8.5e-13 48.2 1.9 1.1e-12 47.9 0.5 1.8 2 1 1 3 3 3 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE76606.1 - 1.4e-08 34.6 3.0 2.1e-08 34.1 0.3 2.4 1 1 1 2 2 2 1 Transposase rve PF00665.21 EIE76606.1 - 0.034 14.2 0.0 0.061 13.4 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain HTH_29 PF13551.1 EIE76606.1 - 0.051 13.7 1.3 0.15 12.1 0.9 1.9 1 1 0 1 1 1 0 Winged helix-turn helix HTH_12 PF08461.5 EIE76606.1 - 0.089 12.5 0.2 0.25 11.1 0.0 1.8 2 0 0 2 2 2 0 Ribonuclease R winged-helix domain ELL PF10390.4 EIE76606.1 - 0.12 11.5 0.8 0.28 10.3 0.5 1.6 1 0 0 1 1 1 0 RNA polymerase II elongation factor ELL HTH_32 PF13565.1 EIE76606.1 - 0.19 12.5 4.2 0.16 12.7 0.5 2.6 4 0 0 4 4 4 0 Homeodomain-like domain HTH_33 PF13592.1 EIE76606.1 - 0.23 11.0 1.3 0.74 9.4 0.0 2.5 3 0 0 3 3 3 0 Winged helix-turn helix HTH_21 PF13276.1 EIE76606.1 - 0.32 11.0 3.1 0.87 9.6 0.0 2.7 3 0 0 3 3 3 0 HTH-like domain NFRKB_winged PF14465.1 EIE76606.1 - 0.66 9.8 5.5 1.9 8.3 0.5 2.7 2 2 0 2 2 2 0 NFRKB Winged Helix-like HTH_Tnp_ISL3 PF13542.1 EIE76606.1 - 0.81 8.9 3.5 0.81 8.9 0.1 2.6 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 DUF1033 PF06279.6 EIE76606.1 - 1.7 8.5 6.3 0.49 10.2 0.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1033) DDE_Tnp_IS1595 PF12762.2 EIE76607.1 - 2.3e-06 27.5 0.1 4.1e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 ISXO2-like transposase domain DUF4119 PF13494.1 EIE76608.1 - 0.05 13.5 0.9 0.12 12.4 0.6 1.6 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF4119) NurA PF09376.5 EIE76608.1 - 0.099 12.1 0.1 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 NurA domain PRKCSH PF07915.8 EIE76608.1 - 0.72 10.6 3.5 0.32 11.8 0.5 1.9 2 0 0 2 2 2 0 Glucosidase II beta subunit-like protein DDE_3 PF13358.1 EIE76609.1 - 1.3e-18 67.1 0.4 9.5e-18 64.3 0.0 2.4 3 0 0 3 3 3 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE76609.1 - 3.6e-10 39.7 0.6 9.1e-10 38.4 0.4 1.8 1 0 0 1 1 1 1 Transposase DUF3860 PF12976.2 EIE76611.1 - 0.062 13.1 0.2 0.9 9.3 0.0 2.4 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3860) SWIM PF04434.12 EIE76615.1 - 0.027 13.9 2.5 0.027 13.9 1.7 2.1 2 0 0 2 2 2 0 SWIM zinc finger KRTAP PF11759.3 EIE76615.1 - 0.035 14.3 14.0 0.041 14.1 9.7 1.2 1 0 0 1 1 1 0 Keratin-associated matrix DUF1700 PF08006.6 EIE76617.1 - 6.1 6.0 9.4 7.4 5.8 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) SseC PF04888.7 EIE76617.1 - 8.2 5.6 8.7 9.8 5.4 6.1 1.0 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family DDE_3 PF13358.1 EIE76618.1 - 7.7e-19 67.8 0.0 1.5e-18 66.9 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.1 EIE76618.1 - 1.4e-05 24.5 0.0 2.8e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.1 EIE76618.1 - 0.00061 19.3 0.0 0.0024 17.4 0.0 2.0 2 0 0 2 2 2 1 Homeodomain-like domain HTH_7 PF02796.10 EIE76618.1 - 0.0018 18.0 0.2 0.089 12.6 0.0 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_28 PF13518.1 EIE76618.1 - 0.0022 17.9 0.0 0.0047 16.8 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.7 EIE76618.1 - 0.0032 16.9 0.0 0.021 14.3 0.0 2.1 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_29 PF13551.1 EIE76618.1 - 0.02 15.0 0.0 0.054 13.6 0.0 1.7 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_4 PF13613.1 EIE76618.1 - 0.043 13.3 1.4 0.049 13.1 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix of DDE superfamily endonuclease DUF2857 PF11198.3 EIE76618.1 - 0.047 13.2 0.1 0.081 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2857) CPSase_L_D3 PF02787.14 EIE76618.1 - 0.06 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain Sigma70_r4 PF04545.11 EIE76618.1 - 0.091 12.0 0.0 0.67 9.3 0.0 2.4 3 0 0 3 3 3 0 Sigma-70, region 4 UPF0122 PF04297.9 EIE76618.1 - 0.13 12.3 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like Transposase_21 PF02992.9 EIE76619.1 - 1.7e-21 76.4 0.0 2.6e-21 75.7 0.0 1.2 1 0 0 1 1 1 1 Transposase family tnp2 DUF1258 PF06869.7 EIE76619.1 - 0.0016 17.6 0.0 0.0024 16.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) DUF4218 PF13960.1 EIE76620.1 - 0.034 13.5 0.0 0.091 12.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) 3HCDH_N PF02737.13 EIE76620.1 - 0.079 12.5 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF2873 PF11395.3 EIE76622.1 - 3 7.4 5.4 23 4.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2873) HTH_Tnp_Tc3_2 PF01498.13 EIE76623.1 - 1.5e-08 34.5 2.8 2.1e-07 30.8 1.1 2.7 3 0 0 3 3 3 1 Transposase DDE_3 PF13358.1 EIE76623.1 - 1.2e-07 31.6 0.0 2.1e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_23 PF13384.1 EIE76623.1 - 7.1e-05 22.3 0.1 0.0025 17.4 0.0 2.8 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.1 EIE76623.1 - 0.0025 17.7 0.3 0.32 11.0 0.0 2.7 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_29 PF13551.1 EIE76623.1 - 0.017 15.2 0.6 0.29 11.3 0.0 2.8 2 1 1 3 3 3 0 Winged helix-turn helix HTH_Tnp_ISL3 PF13542.1 EIE76623.1 - 0.064 12.4 0.0 1.3 8.2 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 Sigma70_r4_2 PF08281.7 EIE76623.1 - 0.092 12.2 0.2 0.23 10.9 0.0 1.8 2 0 0 2 2 2 0 Sigma-70, region 4 DDE_3 PF13358.1 EIE76624.1 - 2.4e-15 56.5 0.0 4.7e-15 55.6 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE76624.1 - 2.8e-11 43.3 1.0 5.2e-11 42.4 0.2 1.9 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 EIE76624.1 - 0.0071 16.4 0.2 0.016 15.3 0.0 1.7 2 0 0 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.1 EIE76624.1 - 0.016 14.8 0.1 0.042 13.4 0.1 1.7 1 0 0 1 1 1 0 Homeodomain-like domain HTH_30 PF13556.1 EIE76624.1 - 0.049 13.2 0.0 0.51 9.9 0.0 2.2 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain Asp_protease_2 PF13650.1 EIE76625.1 - 6.5e-08 32.9 0.0 1.1e-07 32.2 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 EIE76625.1 - 2e-07 30.8 0.1 1e-06 28.5 0.0 2.2 1 1 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EIE76625.1 - 0.0012 18.6 0.0 0.0026 17.5 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.5 EIE76625.1 - 0.0024 17.4 0.1 0.0062 16.0 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease DUF3479 PF11965.3 EIE76625.1 - 0.0093 15.7 0.1 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3479) Peptidase_A2E PF12382.3 EIE76625.1 - 0.017 14.9 0.0 0.035 13.9 0.0 1.4 1 0 0 1 1 1 0 Retrotransposon peptidase Peptidase_M3_N PF08439.5 EIE76625.1 - 0.05 13.6 0.3 0.05 13.6 0.2 2.5 4 0 0 4 4 4 0 Oligopeptidase F YgaB PF14182.1 EIE76625.1 - 0.45 10.7 5.7 14 5.9 0.1 3.7 3 1 0 3 3 3 0 YgaB-like protein rve PF00665.21 EIE76626.1 - 1.3e-17 63.9 0.0 2.9e-17 62.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 EIE76626.1 - 2.2e-09 36.8 0.5 4.7e-09 35.7 0.3 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVT_1 PF00078.22 EIE76626.1 - 1.5e-06 27.7 0.0 2.9e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Tudor-knot PF11717.3 EIE76626.1 - 0.0093 15.6 0.1 0.035 13.8 0.1 2.0 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain zf-RING_2 PF13639.1 EIE76627.1 - 1e-12 47.6 6.3 1.9e-12 46.8 4.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EIE76627.1 - 9.9e-10 37.9 5.2 2.1e-09 36.8 3.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIE76627.1 - 2.4e-09 36.7 3.7 4.9e-09 35.7 2.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EIE76627.1 - 8.4e-09 35.3 7.2 1.8e-08 34.2 5.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EIE76627.1 - 5.3e-07 29.6 1.7 5.3e-07 29.6 1.2 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EIE76627.1 - 1.6e-06 27.6 6.9 3.3e-06 26.6 4.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EIE76627.1 - 0.002 17.8 0.5 0.002 17.8 0.3 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_4 PF14570.1 EIE76627.1 - 0.0031 17.0 6.0 0.0057 16.2 4.2 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 EIE76627.1 - 0.0099 15.7 7.4 0.036 13.9 5.2 2.0 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING DUF1272 PF06906.6 EIE76627.1 - 1.8 8.4 5.4 4.4 7.2 3.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) ACPS PF01648.15 EIE76628.1 - 2.5e-17 62.7 0.0 6.8e-17 61.3 0.0 1.8 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.17 EIE76628.1 - 1.6e-10 40.8 0.0 3.7e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain CRAL_TRIO PF00650.15 EIE76629.1 - 7.8e-36 122.9 0.0 1.2e-35 122.3 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EIE76629.1 - 1.2e-12 47.7 0.6 4.7e-12 45.8 0.0 2.2 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EIE76629.1 - 3.1e-07 30.3 0.0 5.4e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Adeno_E1B_55K PF01696.12 EIE76629.1 - 2.5 6.4 5.7 8.7 4.6 0.3 2.2 2 0 0 2 2 2 0 Adenovirus EB1 55K protein / large t-antigen Glyco_hydro_18 PF00704.23 EIE76630.1 - 1.5e-64 218.6 9.0 1.5e-64 218.6 6.2 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 Peptidase_S49_N PF08496.5 EIE76630.1 - 0.011 15.5 7.4 0.017 14.9 5.1 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal YqfQ PF14181.1 EIE76630.1 - 0.014 15.4 13.3 2.3 8.2 0.1 3.2 3 0 0 3 3 3 0 YqfQ-like protein Otopetrin PF03189.8 EIE76630.1 - 0.16 10.8 1.4 0.19 10.6 1.0 1.1 1 0 0 1 1 1 0 Otopetrin CENP-B_dimeris PF09026.5 EIE76631.1 - 0.12 12.6 1.2 0.12 12.6 0.8 1.1 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DNA_pol_phi PF04931.8 EIE76631.1 - 0.18 9.5 2.7 0.18 9.5 1.9 1.0 1 0 0 1 1 1 0 DNA polymerase phi Tfb2 PF03849.9 EIE76633.1 - 2.6e-77 259.9 10.8 1.8e-76 257.2 7.5 1.9 1 1 0 1 1 1 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 EIE76633.1 - 1.6e-06 27.9 0.0 4e-06 26.5 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HSBP1 PF06825.7 EIE76633.1 - 0.022 14.3 0.1 0.069 12.7 0.0 1.8 1 0 0 1 1 1 0 Heat shock factor binding protein 1 SinI PF08671.5 EIE76633.1 - 0.13 11.6 0.0 0.28 10.6 0.0 1.5 1 0 0 1 1 1 0 Anti-repressor SinI GST_C PF00043.20 EIE76634.1 - 2.2e-06 27.5 0.0 3.3e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EIE76634.1 - 1.4e-05 25.4 0.0 3e-05 24.4 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EIE76634.1 - 0.00031 20.8 0.0 0.00058 19.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIE76634.1 - 0.003 17.4 0.0 0.0059 16.4 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 EIE76634.1 - 0.1 12.5 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin GST_N_3 PF13417.1 EIE76634.1 - 0.14 12.3 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DUF4469 PF14734.1 EIE76635.1 - 0.017 15.0 0.1 0.098 12.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4469) with IG-like fold Glyco_hydro_31 PF01055.21 EIE76636.1 - 2.5e-70 237.4 0.6 3.4e-70 237.0 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EIE76636.1 - 3.4e-06 26.8 0.1 2e-05 24.3 0.0 2.4 2 1 0 2 2 2 1 Galactose mutarotase-like SHNi-TPR PF10516.4 EIE76637.1 - 1.9e-12 46.2 2.7 5.7e-11 41.4 0.6 2.7 2 0 0 2 2 2 1 SHNi-TPR TPR_11 PF13414.1 EIE76637.1 - 9.2e-10 38.0 11.5 3.7e-05 23.2 2.5 3.4 2 1 1 3 3 3 3 TPR repeat TPR_12 PF13424.1 EIE76637.1 - 2.8e-08 33.5 2.6 2.8e-08 33.5 1.8 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EIE76637.1 - 1.1e-06 27.9 5.5 0.03 13.9 0.0 4.1 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EIE76637.1 - 0.00011 22.8 6.6 0.0084 16.7 1.9 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EIE76637.1 - 0.0006 19.5 15.1 0.14 12.1 0.0 5.0 3 1 2 5 5 5 1 Tetratricopeptide repeat Apc3 PF12895.2 EIE76637.1 - 0.0059 16.7 8.5 0.057 13.5 2.2 3.5 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 EIE76637.1 - 0.0062 16.6 8.8 0.19 11.9 0.1 4.3 4 1 1 5 5 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EIE76637.1 - 0.0074 16.0 5.2 3.5 7.6 0.1 4.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EIE76637.1 - 0.0076 15.9 8.5 1.7 8.6 0.4 4.1 2 1 3 5 5 4 3 Tetratricopeptide repeat TPR_6 PF13174.1 EIE76637.1 - 0.017 15.5 6.9 5 7.8 0.1 4.2 4 0 0 4 4 3 0 Tetratricopeptide repeat DUF1722 PF08349.6 EIE76637.1 - 0.04 13.8 1.7 0.089 12.6 0.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1722) TPR_19 PF14559.1 EIE76637.1 - 0.045 14.0 13.1 5.5 7.3 0.3 5.4 5 1 0 5 5 5 0 Tetratricopeptide repeat Allexi_40kDa PF05549.6 EIE76637.1 - 0.059 12.6 3.2 0.13 11.5 2.2 1.6 1 0 0 1 1 1 0 Allexivirus 40kDa protein TPR_14 PF13428.1 EIE76637.1 - 0.066 13.8 2.7 9.5 7.1 0.2 4.3 2 1 2 4 4 4 0 Tetratricopeptide repeat Reo_sigmaC PF04582.7 EIE76637.1 - 0.099 11.7 5.1 0.14 11.3 3.2 1.4 1 1 0 1 1 1 0 Reovirus sigma C capsid protein SPO22 PF08631.5 EIE76637.1 - 0.12 11.4 14.4 0.1 11.6 0.6 3.2 2 1 2 4 4 4 0 Meiosis protein SPO22/ZIP4 like GET2 PF08690.5 EIE76637.1 - 2.1 7.5 20.2 0.031 13.5 6.9 2.0 2 0 0 2 2 2 0 GET complex subunit GET2 PilJ PF13675.1 EIE76637.1 - 2.8 8.2 7.0 0.3 11.4 0.9 2.4 3 1 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term Ribosomal_L4 PF00573.17 EIE76638.1 - 2.8e-57 193.2 0.1 3.1e-57 193.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family PRELI PF04707.9 EIE76638.1 - 0.025 14.1 0.1 0.033 13.7 0.1 1.2 1 0 0 1 1 1 0 PRELI-like family DEAD PF00270.24 EIE76639.1 - 3.5e-44 150.2 0.0 1.5e-43 148.1 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIE76639.1 - 2.3e-24 85.0 0.0 4.6e-24 84.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RanBP PF00641.13 EIE76639.1 - 1.2e-20 72.2 14.2 4.2e-11 41.7 1.7 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others ResIII PF04851.10 EIE76639.1 - 0.00022 21.0 0.0 0.0011 18.8 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DZR PF12773.2 EIE76639.1 - 0.44 10.4 9.3 1 9.1 6.5 1.7 1 0 0 1 1 1 0 Double zinc ribbon Ras PF00071.17 EIE76640.1 - 2.7e-54 182.9 0.0 3.1e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIE76640.1 - 3.6e-16 59.7 0.1 7e-16 58.8 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EIE76640.1 - 2.4e-10 39.9 0.0 3e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EIE76640.1 - 1.4e-07 31.1 0.0 2.9e-07 30.0 0.0 1.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EIE76640.1 - 0.002 18.0 0.0 0.0042 17.0 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EIE76640.1 - 0.0042 16.3 0.0 0.016 14.4 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B ATP_bind_1 PF03029.12 EIE76640.1 - 0.032 13.7 0.9 0.043 13.3 0.0 1.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF258 PF03193.11 EIE76640.1 - 0.036 13.2 0.1 0.28 10.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 EIE76640.1 - 0.05 13.7 0.8 2.5 8.2 0.6 2.8 1 1 0 1 1 1 0 AAA domain DAP3 PF10236.4 EIE76640.1 - 0.061 12.2 0.3 1.1 8.1 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_25 PF13481.1 EIE76640.1 - 0.13 11.6 0.3 0.26 10.6 0.2 1.8 1 1 0 1 1 1 0 AAA domain PCI PF01399.22 EIE76641.1 - 1.3e-09 38.2 1.6 7.3e-09 35.8 0.1 2.8 2 0 0 2 2 2 1 PCI domain SCO1-SenC PF02630.9 EIE76643.1 - 9e-57 191.4 0.4 1.6e-56 190.6 0.1 1.5 1 1 1 2 2 2 1 SCO1/SenC AhpC-TSA PF00578.16 EIE76643.1 - 0.0084 15.7 0.1 0.022 14.4 0.0 1.8 1 1 0 1 1 1 1 AhpC/TSA family Rad60-SLD PF11976.3 EIE76644.1 - 1.6e-24 85.3 0.1 2e-24 85.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EIE76644.1 - 2e-11 43.0 0.0 2.6e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Lzipper-MIP1 PF14389.1 EIE76645.1 - 0.46 10.6 5.0 1.4 9.0 3.5 1.8 1 1 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 zf-RING_2 PF13639.1 EIE76646.1 - 9.5e-15 54.1 5.7 1.5e-14 53.5 4.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EIE76646.1 - 7e-10 38.8 4.0 1.4e-09 37.9 2.8 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EIE76646.1 - 7.3e-09 35.2 5.5 1.2e-08 34.5 3.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EIE76646.1 - 2.1e-08 33.6 6.1 3.9e-08 32.8 4.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIE76646.1 - 6e-08 32.5 5.3 9.8e-08 31.8 3.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EIE76646.1 - 1.4e-06 27.8 3.4 2.4e-06 27.1 2.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EIE76646.1 - 4.9e-05 23.0 3.8 0.00011 21.9 2.6 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EIE76646.1 - 0.0043 16.5 4.6 0.0075 15.8 3.2 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RINGv PF12906.2 EIE76646.1 - 0.013 15.5 7.9 0.026 14.5 5.5 1.6 1 0 0 1 1 1 0 RING-variant domain zf-Nse PF11789.3 EIE76646.1 - 0.026 14.0 1.2 0.052 13.0 0.8 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Baculo_RING PF05883.6 EIE76646.1 - 0.067 13.0 0.9 0.14 11.9 0.6 1.5 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-RING-like PF08746.6 EIE76646.1 - 0.17 11.9 6.1 0.4 10.7 4.2 1.6 1 1 0 1 1 1 0 RING-like domain zf-C3HC4_4 PF15227.1 EIE76646.1 - 0.32 10.8 6.2 6.2 6.7 4.4 2.3 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EIE76646.1 - 0.4 10.4 7.6 0.23 11.1 3.3 2.2 2 0 0 2 2 1 0 RING-type zinc-finger Tsg PF04668.7 EIE76646.1 - 0.69 10.1 5.4 0.44 10.7 1.2 2.6 1 1 2 3 3 3 0 Twisted gastrulation (Tsg) protein conserved region PHD PF00628.24 EIE76646.1 - 0.78 9.4 6.5 1.6 8.5 4.5 1.5 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.3 EIE76646.1 - 4.2 7.4 6.3 14 5.6 4.4 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain OmpH PF03938.9 EIE76647.1 - 0.047 13.6 7.4 0.092 12.6 3.7 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) zf-C2H2 PF00096.21 EIE76647.1 - 0.22 11.9 2.9 0.32 11.4 1.3 1.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type MAS20 PF02064.10 EIE76647.1 - 3.2 7.6 9.4 20 5.0 5.1 2.4 2 0 0 2 2 2 0 MAS20 protein import receptor DUF1771 PF08590.5 EIE76648.1 - 3.7e-15 55.6 3.5 3.7e-15 55.6 2.4 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.16 EIE76648.1 - 4.7e-11 42.7 0.1 8.4e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 Smr domain CUE PF02845.11 EIE76648.1 - 2.3e-05 23.7 0.5 5.5e-05 22.5 0.4 1.7 1 0 0 1 1 1 1 CUE domain zf-CCCH PF00642.19 EIE76648.1 - 7.7e-05 22.2 7.2 0.00068 19.2 0.2 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) SnAC PF14619.1 EIE76648.1 - 0.18 11.9 1.7 0.79 9.9 0.3 2.5 2 0 0 2 2 2 0 Snf2-ATP coupling, chromatin remodelling complex DPBB_1 PF03330.13 EIE76649.1 - 6.5e-08 32.4 0.1 1.1e-07 31.7 0.1 1.4 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EIE76649.1 - 0.0044 16.6 0.5 0.02 14.5 0.1 1.9 1 1 1 2 2 2 1 Barwin family zf-ISL3 PF14690.1 EIE76649.1 - 0.076 13.0 1.8 4 7.5 0.2 2.6 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 WD40 PF00400.27 EIE76651.1 - 6.9e-66 215.9 21.7 3.5e-11 42.5 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EIE76651.1 - 1.3e-06 28.3 0.2 1.2e-05 25.0 0.0 2.3 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EIE76651.1 - 2.9e-06 25.7 10.1 0.0099 14.0 0.2 5.1 2 2 2 4 4 4 4 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 EIE76651.1 - 0.011 14.0 0.0 1.1 7.5 0.0 2.6 2 1 0 2 2 2 0 Cytochrome D1 heme domain Nbas_N PF15492.1 EIE76651.1 - 0.014 14.5 0.0 3.3 6.7 0.0 2.5 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal adh_short_C2 PF13561.1 EIE76652.1 - 1.3e-22 80.7 0.1 6.8e-22 78.4 0.0 1.7 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EIE76652.1 - 4.5e-15 55.9 0.0 5.6e-14 52.3 0.0 2.2 1 1 1 2 2 2 1 short chain dehydrogenase DUF1776 PF08643.5 EIE76652.1 - 0.011 14.9 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) TFIIB PF00382.14 EIE76652.1 - 0.11 12.3 0.1 0.79 9.5 0.0 2.2 2 0 0 2 2 2 0 Transcription factor TFIIB repeat zf-HIT PF04438.11 EIE76654.1 - 2.4e-10 39.8 10.6 3.9e-10 39.1 7.3 1.4 1 0 0 1 1 1 1 HIT zinc finger YL1_C PF08265.6 EIE76654.1 - 0.04 13.4 0.0 0.065 12.8 0.0 1.3 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain PolC_DP2 PF03833.8 EIE76654.1 - 0.067 10.8 2.0 0.07 10.7 1.4 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Shisa PF13908.1 EIE76654.1 - 0.28 11.3 9.7 0.37 10.9 6.8 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Ceramidase_alk PF04734.8 EIE76655.1 - 8.9e-176 585.6 0.0 1.2e-174 581.9 0.0 1.9 1 1 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase DEAD PF00270.24 EIE76656.1 - 3.5e-42 143.7 0.0 4.7e-40 136.8 0.0 3.3 4 0 0 4 4 4 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIE76656.1 - 7.2e-26 89.8 0.0 2e-25 88.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 EIE76656.1 - 0.0064 16.4 0.3 0.039 13.8 0.0 2.4 3 0 0 3 3 3 1 Helicase C-terminal domain zf-CCHC_4 PF14392.1 EIE76656.1 - 0.01 15.4 0.8 0.023 14.3 0.6 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.18 EIE76656.1 - 0.011 15.6 3.1 0.02 14.8 2.1 1.5 1 0 0 1 1 1 0 Zinc knuckle CMS1 PF14617.1 EIE76656.1 - 0.036 13.1 1.8 0.19 10.7 0.0 2.5 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit SecA_DEAD PF07517.9 EIE76656.1 - 0.083 12.1 0.0 0.2 10.8 0.0 1.6 1 0 0 1 1 1 0 SecA DEAD-like domain zf-CCHC_2 PF13696.1 EIE76656.1 - 7.9 6.0 6.2 0.53 9.8 0.3 2.0 2 0 0 2 2 2 0 Zinc knuckle Chromo PF00385.19 EIE76657.1 - 0.00014 21.4 0.1 0.002 17.7 0.1 2.5 1 1 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF778 PF05608.7 EIE76657.1 - 0.015 15.2 0.6 0.031 14.2 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF778) CDC45 PF02724.9 EIE76657.1 - 3.1 5.7 19.8 4.7 5.1 13.7 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF1387 PF07139.6 EIE76657.1 - 6.2 6.3 21.8 10 5.6 15.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) DDE_3 PF13358.1 EIE76658.1 - 6.6e-25 87.5 0.0 1.3e-24 86.5 0.0 1.6 1 1 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE76658.1 - 0.0005 20.1 0.0 0.00089 19.3 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain HTH_28 PF13518.1 EIE76658.1 - 0.0074 16.2 0.0 0.019 14.9 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain Hexose_dehydrat PF03559.9 EIE76658.1 - 0.12 11.4 0.1 0.19 10.7 0.1 1.2 1 0 0 1 1 1 0 NDP-hexose 2,3-dehydratase HTH_23 PF13384.1 EIE76658.1 - 0.12 12.0 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain DUF4258 PF14076.1 EIE76659.1 - 0.069 13.1 0.1 1 9.3 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4258) DDE_3 PF13358.1 EIE76660.1 - 9.4e-25 87.0 0.0 1.7e-24 86.2 0.0 1.7 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 EIE76660.1 - 2.2e-05 24.5 0.0 3.8e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.13 EIE76660.1 - 0.00059 19.8 0.0 0.0029 17.6 0.0 2.3 1 1 0 1 1 1 1 Transposase rve PF00665.21 EIE76660.1 - 0.0006 19.9 0.0 0.0011 19.0 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain HTH_28 PF13518.1 EIE76660.1 - 0.0094 15.9 0.1 0.024 14.6 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_32 PF13565.1 EIE76660.1 - 0.12 13.1 0.0 0.29 11.9 0.0 1.7 1 0 0 1 1 1 0 Homeodomain-like domain HTH_23 PF13384.1 EIE76660.1 - 0.15 11.7 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain DUF342 PF03961.8 EIE76663.1 - 0.046 12.1 1.0 0.062 11.7 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Val_tRNA-synt_C PF10458.4 EIE76663.1 - 2 8.5 5.6 0.87 9.7 0.2 2.7 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm DUF883 PF05957.8 EIE76663.1 - 3.2 8.2 5.6 12 6.3 0.1 2.6 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) TMF_DNA_bd PF12329.3 EIE76663.1 - 4.1 7.2 8.9 0.25 11.1 0.9 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding GTP_EFTU PF00009.22 EIE76664.1 - 5.2e-54 182.5 0.0 9.8e-54 181.6 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 EIE76664.1 - 6.2e-14 51.6 0.0 2.6e-13 49.6 0.0 2.1 2 0 0 2 2 2 1 Elongation factor G C-terminus EFG_II PF14492.1 EIE76664.1 - 8.1e-10 38.4 0.1 1.8e-09 37.2 0.1 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 EIE76664.1 - 3.8e-07 30.1 0.0 1.1e-06 28.6 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.13 EIE76664.1 - 0.00019 20.9 0.4 0.014 14.9 0.0 3.8 3 1 0 3 3 3 1 Elongation factor G, domain IV DUSP PF06337.7 EIE76665.1 - 2.9e-06 27.5 0.6 6.7e-06 26.4 0.4 1.5 1 0 0 1 1 1 1 DUSP domain DUF4451 PF14616.1 EIE76665.1 - 0.031 14.0 1.7 1.8 8.3 0.3 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4451) zf-UBP PF02148.14 EIE76665.1 - 0.084 12.9 4.8 0.22 11.6 3.3 1.8 1 1 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein zf-C2H2 PF00096.21 EIE76666.1 - 3.6e-09 36.4 9.7 3.8e-05 23.7 1.3 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIE76666.1 - 1.1e-08 34.8 12.6 1.4e-07 31.4 1.6 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EIE76666.1 - 7.1e-07 29.1 7.5 0.0029 17.8 0.8 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EIE76666.1 - 0.0052 16.6 6.8 0.0071 16.2 0.7 2.8 3 0 0 3 3 3 1 C2H2-type zinc finger Cofilin_ADF PF00241.15 EIE76667.1 - 1.6e-24 86.2 4.6 2.4e-13 50.0 1.5 2.2 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein DUF1183 PF06682.7 EIE76670.1 - 0.00052 19.7 0.0 0.00057 19.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) OppC_N PF12911.2 EIE76670.1 - 0.0026 17.0 1.0 0.46 9.8 0.3 2.3 2 0 0 2 2 2 1 N-terminal TM domain of oligopeptide transport permease C FtsL PF04999.8 EIE76670.1 - 0.003 17.2 0.8 0.0077 15.9 0.6 1.7 1 0 0 1 1 1 1 Cell division protein FtsL DUF4446 PF14584.1 EIE76670.1 - 0.0033 17.2 1.3 0.0051 16.6 0.6 1.5 1 1 1 2 2 2 1 Protein of unknown function (DUF4446) NicO PF03824.11 EIE76670.1 - 0.0045 16.3 0.5 0.0061 15.9 0.3 1.3 1 0 0 1 1 1 1 High-affinity nickel-transport protein HAMP PF00672.20 EIE76670.1 - 0.0076 16.4 1.7 0.0079 16.3 0.3 1.7 2 0 0 2 2 2 1 HAMP domain 7tm_1 PF00001.16 EIE76670.1 - 0.018 14.2 0.3 0.02 14.0 0.2 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) TMEM154 PF15102.1 EIE76670.1 - 0.022 14.4 0.2 0.022 14.4 0.2 1.8 1 1 1 2 2 2 0 TMEM154 protein family Vpu PF00558.14 EIE76670.1 - 0.024 14.2 0.8 0.045 13.3 0.5 1.5 1 0 0 1 1 1 0 Vpu protein Ctr PF04145.10 EIE76670.1 - 0.033 14.2 0.1 0.042 13.8 0.1 1.2 1 0 0 1 1 1 0 Ctr copper transporter family ABC_membrane PF00664.18 EIE76670.1 - 0.033 13.5 0.8 1.3 8.3 0.4 2.0 2 0 0 2 2 2 0 ABC transporter transmembrane region PspB PF06667.7 EIE76670.1 - 0.041 13.8 0.3 0.079 12.9 0.2 1.5 1 0 0 1 1 1 0 Phage shock protein B Oxidored_q3 PF00499.15 EIE76670.1 - 0.051 13.3 3.1 0.072 12.8 2.1 1.2 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 DUF2500 PF10694.4 EIE76670.1 - 0.053 13.5 2.8 1.5 8.8 1.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2500) DUF2681 PF10883.3 EIE76670.1 - 0.061 13.5 0.3 0.061 13.5 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) 60KD_IMP PF02096.15 EIE76670.1 - 0.081 12.5 5.4 0.016 14.8 1.4 1.5 1 1 0 1 1 1 0 60Kd inner membrane protein Herpes_glycop PF01528.11 EIE76670.1 - 0.089 11.4 3.2 0.18 10.4 0.2 2.0 1 1 1 2 2 2 0 Herpesvirus glycoprotein M P12 PF12669.2 EIE76670.1 - 0.091 12.9 0.9 0.16 12.1 0.6 1.4 1 0 0 1 1 1 0 Virus attachment protein p12 family DUF2393 PF09624.5 EIE76670.1 - 0.092 12.2 0.2 0.092 12.2 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2393) HemY_N PF07219.8 EIE76670.1 - 0.094 12.2 0.4 0.19 11.2 0.3 1.5 1 0 0 1 1 1 0 HemY protein N-terminus TMEM61 PF15105.1 EIE76670.1 - 0.1 12.0 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 TMEM61 protein family Lig_chan PF00060.21 EIE76670.1 - 0.12 12.1 0.3 0.2 11.3 0.1 1.7 2 0 0 2 2 2 0 Ligand-gated ion channel Tetraspannin PF00335.15 EIE76670.1 - 0.17 11.1 1.6 0.16 11.2 0.2 1.5 1 1 0 1 1 1 0 Tetraspanin family DUF2140 PF09911.4 EIE76670.1 - 0.19 10.8 1.4 0.27 10.4 0.3 1.7 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2140) ODV-E18 PF10717.4 EIE76670.1 - 1.3 8.5 9.8 2.7 7.5 1.9 2.3 1 1 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 EphA2_TM PF14575.1 EIE76670.1 - 1.4 9.3 3.3 1 9.8 0.1 2.2 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain PfkB PF00294.19 EIE76671.1 - 1e-16 60.9 1.6 3.3e-15 55.9 0.0 2.2 1 1 1 2 2 2 2 pfkB family carbohydrate kinase NPCBM_assoc PF10633.4 EIE76671.1 - 0.12 12.4 2.9 3.8 7.6 0.1 3.4 4 0 0 4 4 4 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Aa_trans PF01490.13 EIE76672.1 - 1.9e-82 276.9 36.9 2.5e-82 276.5 25.5 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein UPF0233 PF06781.7 EIE76672.1 - 0.12 12.0 2.0 0.62 9.7 0.4 2.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0233) DHQ_synthase PF01761.15 EIE76673.1 - 2.8e-94 314.8 0.0 4.3e-94 314.2 0.0 1.3 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.10 EIE76673.1 - 3.2e-44 151.2 0.0 1.1e-43 149.5 0.0 1.8 2 0 0 2 2 2 1 Type I 3-dehydroquinase Fe-ADH_2 PF13685.1 EIE76673.1 - 3.2e-08 33.2 0.1 6.4e-08 32.2 0.1 1.5 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.14 EIE76673.1 - 0.0017 17.0 0.4 0.0057 15.3 0.3 1.7 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Na_Ca_ex PF01699.19 EIE76675.1 - 2.1e-30 105.1 32.2 4.5e-20 71.6 9.2 4.1 3 1 1 4 4 4 3 Sodium/calcium exchanger protein SET PF00856.23 EIE76676.1 - 1.7e-23 83.6 0.4 1.7e-23 83.6 0.3 3.3 2 2 0 2 2 2 1 SET domain RRM_6 PF14259.1 EIE76676.1 - 2.5e-09 37.0 0.0 2.3e-08 33.9 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EIE76676.1 - 1.3e-07 31.1 0.0 3.2e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) N-SET PF11764.3 EIE76676.1 - 3.7e-07 30.1 6.3 3.7e-07 30.1 4.4 4.4 1 1 1 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component N RRM_5 PF13893.1 EIE76676.1 - 0.0054 16.5 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SAF PF08666.7 EIE76676.1 - 0.032 14.6 0.0 2.4 8.6 0.0 3.2 3 0 0 3 3 3 0 SAF domain IBR PF01485.16 EIE76676.1 - 0.051 13.4 2.0 0.094 12.6 0.6 1.9 2 0 0 2 2 2 0 IBR domain HMG14_17 PF01101.13 EIE76676.1 - 1.1 9.9 13.6 3.1 8.5 9.5 1.7 1 0 0 1 1 1 0 HMG14 and HMG17 Cauli_DNA-bind PF03310.8 EIE76678.1 - 0.43 10.4 3.6 0.34 10.7 1.1 1.9 2 0 0 2 2 2 0 Caulimovirus DNA-binding protein Gti1_Pac2 PF09729.4 EIE76678.1 - 0.47 10.2 0.1 0.47 10.2 0.0 2.3 1 1 1 2 2 2 0 Gti1/Pac2 family PDGF_N PF04692.8 EIE76678.1 - 9.9 6.7 9.7 19 5.8 0.3 2.9 2 1 1 3 3 3 0 Platelet-derived growth factor, N terminal region SCP2 PF02036.12 EIE76679.1 - 3.5e-24 85.0 0.6 4e-24 84.8 0.4 1.0 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 EIE76679.1 - 0.00023 21.1 0.1 0.00032 20.6 0.1 1.4 1 1 0 1 1 1 1 Alkyl sulfatase C-terminal DUF1700 PF08006.6 EIE76679.1 - 0.13 11.5 0.4 0.18 11.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) RabGAP-TBC PF00566.13 EIE76680.1 - 4.4e-08 32.8 1.5 0.00036 20.0 0.3 2.3 1 1 1 2 2 2 2 Rab-GTPase-TBC domain SET PF00856.23 EIE76681.1 - 1.3e-10 41.8 0.0 1.6e-07 31.8 0.0 2.1 1 1 1 2 2 2 2 SET domain DEAD PF00270.24 EIE76683.1 - 1.9e-45 154.4 0.1 5.8e-45 152.8 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EIE76683.1 - 3.9e-26 90.3 0.4 8.5e-26 89.2 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EIE76683.1 - 1.3e-22 79.3 0.0 3.7e-22 77.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain YycC PF14174.1 EIE76684.1 - 0.13 11.9 1.0 0.17 11.5 0.1 1.7 2 0 0 2 2 2 0 YycC-like protein BSP_II PF05432.6 EIE76689.1 - 0.12 11.6 9.9 0.12 11.6 6.8 1.0 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) BTV_NS2 PF04514.7 EIE76689.1 - 0.15 10.9 3.4 0.14 11.0 2.3 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF4637 PF15470.1 EIE76689.1 - 0.41 10.2 3.0 0.42 10.1 2.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) GOLD_2 PF13897.1 EIE76689.1 - 0.45 10.7 2.5 0.51 10.5 1.7 1.0 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking FAM176 PF14851.1 EIE76689.1 - 0.47 10.1 2.9 0.5 10.0 2.0 1.1 1 0 0 1 1 1 0 FAM176 family Nucleoplasmin PF03066.10 EIE76689.1 - 2.5 7.6 8.8 2.5 7.5 6.1 1.2 1 0 0 1 1 1 0 Nucleoplasmin CENP-B_dimeris PF09026.5 EIE76689.1 - 5.5 7.2 12.5 14 6.0 8.7 1.6 1 1 0 1 1 1 0 Centromere protein B dimerisation domain VID27 PF08553.5 EIE76689.1 - 5.8 5.0 7.1 6.4 4.8 4.9 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein Sporozoite_P67 PF05642.6 EIE76689.1 - 7.1 4.3 8.1 6.7 4.4 5.6 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen S-antigen PF05756.6 EIE76689.1 - 9.4 6.2 9.5 11 6.1 6.6 1.1 1 0 0 1 1 1 0 S-antigen protein DUF2457 PF10446.4 EIE76689.1 - 9.6 4.8 10.2 10 4.7 7.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) MULE PF10551.4 EIE76691.1 - 5.3e-07 29.7 0.1 1.6e-06 28.2 0.0 1.8 1 1 1 2 2 2 1 MULE transposase domain NUDIX PF00293.23 EIE76693.1 - 7.5e-07 28.8 0.0 1.3e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain UCH PF00443.24 EIE76694.1 - 1e-20 74.0 0.1 1.6e-20 73.3 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase SoxZ PF08770.6 EIE76694.1 - 0.063 12.6 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Sulphur oxidation protein SoxZ adh_short PF00106.20 EIE76695.1 - 9e-32 110.2 0.4 1.1e-31 109.9 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIE76695.1 - 5e-27 95.2 0.5 1.3e-26 93.8 0.4 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIE76695.1 - 1.4e-16 60.6 0.2 2.1e-16 60.1 0.1 1.2 1 0 0 1 1 1 1 KR domain AdoHcyase_NAD PF00670.16 EIE76695.1 - 4.2e-05 23.4 0.4 8.4e-05 22.4 0.3 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 3HCDH_N PF02737.13 EIE76695.1 - 0.017 14.7 0.1 0.029 14.0 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IGPD PF00475.13 EIE76696.1 - 6.4e-61 204.4 0.2 1.5e-60 203.2 0.1 1.6 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase TRAM_LAG1_CLN8 PF03798.11 EIE76696.1 - 2.6e-39 134.8 27.8 2.6e-39 134.8 19.3 1.8 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 EIE76696.1 - 3.2e-15 55.3 1.7 5.1e-15 54.7 0.0 2.3 2 0 0 2 2 2 1 TRAM1-like protein NOG1 PF06858.9 EIE76697.1 - 0.14 12.0 0.1 0.56 10.1 0.1 2.0 1 1 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) PP2C PF00481.16 EIE76698.1 - 4e-70 236.1 0.1 4.5e-70 235.9 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EIE76698.1 - 1.6e-05 24.4 0.0 2.5e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C DUF4649 PF15507.1 EIE76698.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4649) SIN1 PF05422.7 EIE76699.1 - 5e-49 167.2 0.3 1.9e-48 165.2 0.2 1.7 1 1 0 1 1 1 1 Stress-activated map kinase interacting protein 1 (SIN1) MaoC_dehydrat_N PF13452.1 EIE76700.1 - 3.1e-05 23.7 0.0 5.6e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase MaoC_dehydratas PF01575.14 EIE76700.1 - 0.088 12.1 0.4 0.6 9.4 0.0 2.1 2 0 0 2 2 2 0 MaoC like domain Abhydro_lipase PF04083.11 EIE76701.1 - 1.7e-14 52.9 0.2 6.8e-14 50.9 0.1 2.1 1 1 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_5 PF12695.2 EIE76701.1 - 2.4e-05 24.1 0.0 4.1e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIE76701.1 - 0.00016 21.3 0.1 0.0005 19.6 0.0 1.6 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EIE76701.1 - 0.0005 20.0 0.1 0.002 18.0 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2408 PF10303.4 EIE76702.1 - 4.9e-28 97.8 0.1 3e-20 72.6 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2408) Ins_beta PF03488.9 EIE76702.1 - 0.0032 17.2 0.1 0.0079 15.9 0.1 1.6 2 0 0 2 2 2 1 Nematode insulin-related peptide beta type YqaJ PF09588.5 EIE76702.1 - 0.14 12.1 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 YqaJ-like viral recombinase domain SecY PF00344.15 EIE76703.1 - 9.7e-78 261.5 15.6 1.2e-77 261.2 10.8 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 EIE76703.1 - 6.7e-11 41.5 0.0 1.9e-10 40.0 0.0 1.9 1 0 0 1 1 1 1 Plug domain of Sec61p Polysacc_deac_1 PF01522.16 EIE76704.1 - 1.6e-26 92.3 0.0 2.8e-26 91.5 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase FAD_binding_3 PF01494.14 EIE76705.1 - 1.5e-19 70.2 0.0 4.7e-19 68.6 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EIE76705.1 - 0.00014 21.8 0.0 0.00035 20.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EIE76705.1 - 0.00062 20.1 0.0 0.0031 17.8 0.0 2.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EIE76705.1 - 0.00072 18.5 0.0 0.092 11.6 0.0 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EIE76705.1 - 0.0063 16.4 0.0 0.016 15.1 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIE76705.1 - 0.013 14.0 0.0 0.028 12.8 0.0 1.5 1 0 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.9 EIE76705.1 - 0.023 13.3 0.0 2.8 6.4 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Lycopene_cycl PF05834.7 EIE76705.1 - 0.045 12.6 0.0 0.3 9.9 0.0 2.1 1 1 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 EIE76705.1 - 0.069 11.9 0.0 0.16 10.7 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain PSP1 PF04468.7 EIE76706.1 - 7.6e-09 35.4 0.3 2.3e-08 33.8 0.2 1.9 1 0 0 1 1 1 1 PSP1 C-terminal conserved region FHA PF00498.21 EIE76707.1 - 4.7e-20 71.4 0.0 8e-20 70.7 0.0 1.4 1 0 0 1 1 1 1 FHA domain Fmp27_WPPW PF10359.4 EIE76707.1 - 0.0003 19.3 11.5 0.00035 19.1 7.3 1.6 1 1 1 2 2 2 1 RNA pol II promoter Fmp27 protein domain CDC45 PF02724.9 EIE76707.1 - 0.0041 15.2 12.2 0.0052 14.8 8.5 1.1 1 0 0 1 1 1 1 CDC45-like protein DUF2115 PF09888.4 EIE76707.1 - 0.12 12.4 1.8 0.3 11.1 1.3 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) CemA PF03040.9 EIE76707.1 - 0.29 10.6 3.6 0.44 10.1 2.5 1.2 1 0 0 1 1 1 0 CemA family Neur_chan_LBD PF02931.18 EIE76708.1 - 0.06 12.4 0.0 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel ligand binding domain ING PF12998.2 EIE76709.1 - 0.014 15.6 6.3 0.014 15.6 4.4 1.6 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Myc_N PF01056.13 EIE76709.1 - 0.042 13.0 4.3 0.059 12.5 3.0 1.2 1 0 0 1 1 1 0 Myc amino-terminal region DUF3682 PF12446.3 EIE76709.1 - 1.6 8.9 5.5 2.4 8.4 3.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) CorA PF01544.13 EIE76711.1 - 1.1e-49 169.1 7.9 7.3e-27 94.1 1.7 2.2 1 1 1 2 2 2 2 CorA-like Mg2+ transporter protein BLOC1_2 PF10046.4 EIE76711.1 - 0.028 14.5 3.6 6 7.0 0.0 3.1 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SecY PF00344.15 EIE76712.1 - 2.8e-92 309.3 12.9 3.2e-92 309.1 8.9 1.0 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 EIE76712.1 - 1.5e-14 53.2 0.1 3.7e-14 51.9 0.1 1.8 1 0 0 1 1 1 1 Plug domain of Sec61p UCR_TM PF02921.9 EIE76713.1 - 3.1e-20 72.1 2.6 5.6e-20 71.3 1.8 1.4 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.21 EIE76713.1 - 3.2e-18 65.0 0.0 5.5e-18 64.3 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain DDE_3 PF13358.1 EIE76715.1 - 4.7e-21 75.0 0.0 7.9e-21 74.3 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_23 PF13384.1 EIE76715.1 - 0.00086 18.8 0.0 0.002 17.7 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.1 EIE76715.1 - 0.0077 16.2 0.3 0.019 14.9 0.1 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_29 PF13551.1 EIE76715.1 - 0.013 15.6 0.1 0.028 14.5 0.1 1.5 1 0 0 1 1 1 0 Winged helix-turn helix Gemini_coat PF00844.13 EIE76716.1 - 0.06 12.5 0.3 0.067 12.4 0.2 1.0 1 0 0 1 1 1 0 Geminivirus coat protein/nuclear export factor BR1 family DUF1116 PF06545.6 EIE76716.1 - 0.12 11.4 0.0 0.13 11.3 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1116) SUI1 PF01253.17 EIE76718.1 - 1.8e-13 50.0 0.1 3.8e-13 49.0 0.1 1.6 1 0 0 1 1 1 1 Translation initiation factor SUI1 SWIB PF02201.13 EIE76718.1 - 0.0039 16.8 0.1 0.0098 15.5 0.1 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain Kin17_mid PF10357.4 EIE76718.1 - 0.0075 15.9 2.6 0.025 14.2 0.0 2.8 3 0 0 3 3 3 1 Domain of Kin17 curved DNA-binding protein HTH_29 PF13551.1 EIE76719.1 - 4.4e-09 36.4 0.0 6.1e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.1 EIE76719.1 - 2.8e-05 24.0 0.1 6.4e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_32 PF13565.1 EIE76719.1 - 6.9e-05 23.5 0.0 0.00014 22.5 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_1 PF01527.15 EIE76719.1 - 0.00029 20.7 0.2 0.00039 20.3 0.1 1.4 1 1 0 1 1 1 1 Transposase HTH_23 PF13384.1 EIE76719.1 - 0.00031 20.3 0.1 0.00071 19.1 0.0 1.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_30 PF13556.1 EIE76719.1 - 0.016 14.7 0.0 0.03 13.9 0.0 1.4 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain HTH_17 PF12728.2 EIE76719.1 - 0.051 13.8 0.0 0.32 11.2 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain BDV_P24 PF06595.6 EIE76719.1 - 0.065 12.9 0.0 0.084 12.6 0.0 1.2 1 0 0 1 1 1 0 Borna disease virus P24 protein Terminase_5 PF06056.7 EIE76719.1 - 0.074 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) zf-CCHC PF00098.18 EIE76721.1 - 4.9e-05 23.0 11.2 0.0039 17.0 0.9 2.3 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 EIE76721.1 - 0.004 16.7 5.5 0.0085 15.7 0.2 2.4 2 0 0 2 2 2 1 Zinc knuckle RRM_1 PF00076.17 EIE76721.1 - 0.057 13.0 0.0 0.17 11.5 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC_3 PF13917.1 EIE76721.1 - 3.7 7.3 8.2 2.3 7.9 0.1 2.4 1 1 1 2 2 2 0 Zinc knuckle Zn_ribbon_2 PF12674.2 EIE76721.1 - 7.3 7.0 7.4 34 4.8 0.6 2.6 1 1 1 2 2 2 0 Putative zinc ribbon domain RVT_1 PF00078.22 EIE76722.1 - 1.9e-39 135.2 0.0 2.1e-39 135.0 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.1 EIE76723.1 - 0.0019 18.4 0.2 0.0037 17.5 0.1 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase RVT_1 PF00078.22 EIE76725.1 - 1.2e-36 126.1 0.0 2.3e-36 125.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.1 EIE76725.1 - 6.6e-08 32.7 2.2 6.6e-08 32.7 1.5 2.0 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase DDE_3 PF13358.1 EIE76726.1 - 1e-29 103.1 0.0 2.1e-29 102.1 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 EIE76726.1 - 1.6e-08 34.7 0.0 4.7e-08 33.1 0.0 1.8 1 0 0 1 1 1 1 Winged helix-turn helix zf-CCHC PF00098.18 EIE76726.1 - 1.1e-06 28.2 20.2 4.8e-05 23.0 1.6 3.0 3 0 0 3 3 3 2 Zinc knuckle HTH_28 PF13518.1 EIE76726.1 - 0.0003 20.7 0.1 0.00082 19.3 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_32 PF13565.1 EIE76726.1 - 0.00068 20.3 0.0 0.0025 18.5 0.0 2.0 1 0 0 1 1 1 1 Homeodomain-like domain DDE_1 PF03184.14 EIE76726.1 - 0.0009 18.4 0.1 0.0058 15.7 0.1 2.2 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_1 PF01527.15 EIE76726.1 - 0.0012 18.7 0.7 0.0092 15.9 0.1 2.4 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.1 EIE76726.1 - 0.003 17.1 0.0 0.0084 15.7 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain rve PF00665.21 EIE76726.1 - 0.0034 17.4 0.0 0.0082 16.2 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RRM_1 PF00076.17 EIE76726.1 - 0.014 15.0 0.1 0.38 10.4 0.0 3.1 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC_4 PF14392.1 EIE76726.1 - 0.053 13.1 10.2 0.82 9.3 0.9 2.8 2 0 0 2 2 2 0 Zinc knuckle HTH_30 PF13556.1 EIE76726.1 - 0.093 12.3 0.2 0.27 10.8 0.0 1.9 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain Rho_N PF07498.7 EIE76728.1 - 0.15 11.8 4.2 0.42 10.3 2.9 1.8 1 1 0 1 1 1 0 Rho termination factor, N-terminal domain DAGK_acc PF00609.14 EIE76730.1 - 2.3e-15 57.1 0.0 4.9e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.19 EIE76730.1 - 7e-13 48.1 0.0 1.9e-10 40.2 0.0 2.4 2 0 0 2 2 2 2 Diacylglycerol kinase catalytic domain RGS PF00615.14 EIE76731.1 - 1.4e-08 34.8 0.5 6.1e-08 32.7 0.4 2.0 1 1 0 1 1 1 1 Regulator of G protein signaling domain Chromo PF00385.19 EIE76732.1 - 5e-10 38.9 1.7 5e-10 38.9 1.2 2.3 2 1 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.14 EIE76732.1 - 2.2e-06 27.4 0.1 6.8e-05 22.6 0.0 2.5 2 0 0 2 2 2 1 Chromo shadow domain Oxidored_FMN PF00724.15 EIE76734.1 - 3.9e-106 354.9 0.0 4.4e-106 354.7 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Tautomerase PF01361.16 EIE76734.1 - 0.08 12.5 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 Tautomerase enzyme NmrA PF05368.8 EIE76735.1 - 1.1e-50 172.1 0.4 1.4e-50 171.7 0.3 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EIE76735.1 - 1.9e-24 86.7 0.3 3.1e-24 85.9 0.2 1.4 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EIE76735.1 - 2.7e-07 30.2 0.2 9.8e-07 28.4 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EIE76735.1 - 6.6e-06 25.0 0.3 1.4e-05 23.9 0.1 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EIE76735.1 - 0.00019 21.3 0.7 0.00031 20.7 0.5 1.4 1 0 0 1 1 1 1 short chain dehydrogenase TrkA_N PF02254.13 EIE76735.1 - 0.00052 20.0 0.2 0.001 19.0 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain F420_oxidored PF03807.12 EIE76735.1 - 0.011 16.1 0.6 0.025 14.9 0.4 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_4 PF07993.7 EIE76735.1 - 0.015 14.2 0.3 0.8 8.5 0.0 2.3 1 1 0 2 2 2 0 Male sterility protein KR PF08659.5 EIE76735.1 - 0.051 13.2 0.7 0.087 12.4 0.5 1.3 1 0 0 1 1 1 0 KR domain DUF92 PF01940.11 EIE76737.1 - 2.5e-16 59.5 2.1 3.2e-16 59.1 1.4 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF92 Proteasome PF00227.21 EIE76738.1 - 2.9e-62 209.3 0.2 3.5e-62 209.0 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EIE76738.1 - 1e-14 53.5 0.2 1.7e-14 52.8 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature 4HB_MCP_1 PF12729.2 EIE76739.1 - 0.078 12.3 1.8 0.08 12.2 1.3 1.0 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction FokI_C PF02980.11 EIE76739.1 - 0.085 12.5 0.3 0.088 12.4 0.2 1.0 1 0 0 1 1 1 0 Restriction endonuclease FokI, catalytic domain HSP9_HSP12 PF04119.7 EIE76740.1 - 0.12 12.5 0.8 14 5.8 0.1 2.1 2 0 0 2 2 2 0 Heat shock protein 9/12 DSPc PF00782.15 EIE76741.1 - 7.4e-36 122.6 0.2 4.2e-35 120.2 0.2 1.9 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EIE76741.1 - 9.9e-06 25.0 0.1 1.4e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EIE76741.1 - 0.0039 17.2 0.0 0.0066 16.5 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate DUF1100 PF06500.6 EIE76741.1 - 0.021 13.4 0.0 0.029 12.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) Init_tRNA_PT PF04179.7 EIE76741.1 - 0.036 12.9 0.1 0.044 12.6 0.1 1.2 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase DUF220 PF02713.9 EIE76744.1 - 0.081 12.6 0.3 7.1 6.3 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function DUF220 PAS_3 PF08447.6 EIE76746.1 - 8.7e-12 44.9 0.0 1.9e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS PF00989.19 EIE76746.1 - 1.5e-08 34.3 0.0 2.7e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.1 EIE76746.1 - 3.6e-08 33.7 0.0 1.1e-07 32.2 0.0 1.8 1 1 0 1 1 1 1 PAS domain PAS_11 PF14598.1 EIE76746.1 - 2.4e-06 27.4 0.0 5.8e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS_8 PF13188.1 EIE76746.1 - 0.13 12.1 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 PAS domain PAS_4 PF08448.5 EIE76746.1 - 0.13 12.3 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 PAS fold Cyclin PF08613.6 EIE76747.1 - 2.5e-08 34.4 0.7 5.4e-08 33.3 0.0 1.8 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 EIE76747.1 - 8.4e-06 25.3 0.0 1.6e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Replic_Relax PF13814.1 EIE76747.1 - 0.057 13.2 0.1 0.13 12.0 0.0 1.6 2 0 0 2 2 2 0 Replication-relaxation adh_short_C2 PF13561.1 EIE76748.1 - 2.9e-32 112.3 0.5 3.5e-32 112.0 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EIE76748.1 - 5.7e-32 110.9 0.4 7e-32 110.6 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIE76748.1 - 7.9e-14 51.7 0.2 1.1e-13 51.2 0.1 1.1 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 EIE76748.1 - 0.00014 20.7 1.2 0.00018 20.2 0.9 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EIE76748.1 - 0.00063 19.2 0.1 0.00079 18.9 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIE76748.1 - 0.0055 16.7 0.1 0.015 15.3 0.1 1.7 1 1 0 1 1 1 1 NADH(P)-binding AnfO_nitrog PF09582.5 EIE76748.1 - 0.12 11.4 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) ETF PF01012.16 EIE76748.1 - 0.16 11.7 1.2 0.45 10.2 0.6 1.8 1 1 1 2 2 2 0 Electron transfer flavoprotein domain Pkinase PF00069.20 EIE76749.1 - 7.7e-22 77.6 1.7 1.4e-21 76.8 0.0 2.3 2 1 0 2 2 2 1 Protein kinase domain Pox_P35 PF03213.9 EIE76749.1 - 0.1 11.6 0.1 0.1 11.6 0.1 3.1 3 0 0 3 3 3 0 Poxvirus P35 protein GTP_EFTU PF00009.22 EIE76751.1 - 8.5e-61 204.6 0.4 1.2e-60 204.1 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EIE76751.1 - 3.4e-32 110.5 0.3 1.6e-31 108.4 0.1 2.2 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EIE76751.1 - 4.5e-16 58.7 2.8 4.5e-16 58.7 1.9 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EIE76751.1 - 3.8e-05 23.6 0.0 6.9e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EIE76751.1 - 0.0059 17.0 0.0 0.01 16.3 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein cobW PF02492.14 EIE76751.1 - 0.046 13.1 0.6 0.082 12.3 0.0 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 EIE76751.1 - 0.07 12.6 0.3 6.3 6.2 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Pkinase PF00069.20 EIE76752.1 - 7.1e-73 244.9 0.0 8.6e-73 244.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE76752.1 - 2.2e-30 105.6 0.0 2.9e-30 105.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE76752.1 - 0.00021 20.3 0.0 0.0017 17.4 0.0 2.0 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.9 EIE76752.1 - 0.0075 15.3 0.5 0.012 14.6 0.1 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIE76752.1 - 0.057 13.1 0.0 0.087 12.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF4337 PF14235.1 EIE76754.1 - 1.4 8.7 6.6 2.4 7.9 4.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) FMN_red PF03358.10 EIE76756.1 - 1.1e-12 47.7 0.0 2.1e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 EIE76756.1 - 7.9e-08 32.0 0.0 1.4e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.20 EIE76756.1 - 0.0026 17.7 1.0 0.0038 17.2 0.0 1.9 3 0 0 3 3 3 1 Flavodoxin FMN_red PF03358.10 EIE76757.1 - 1.1e-12 47.6 0.0 1.7e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 EIE76757.1 - 5.9e-07 29.1 0.0 7.5e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.20 EIE76757.1 - 1.3e-05 25.2 0.0 2.4e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin zf-C2H2 PF00096.21 EIE76758.1 - 0.00011 22.2 4.4 0.00011 22.2 3.0 3.9 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIE76758.1 - 0.00016 21.7 5.0 0.00016 21.7 3.5 2.8 2 1 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EIE76758.1 - 0.0013 18.8 2.3 0.0013 18.8 1.6 4.2 4 0 0 4 4 4 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EIE76758.1 - 0.0018 18.3 1.4 0.0018 18.3 1.0 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EIE76758.1 - 0.018 15.2 1.5 0.018 15.2 1.0 3.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type AMP-binding PF00501.23 EIE76759.1 - 3.4e-75 253.0 0.0 4e-75 252.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EIE76759.1 - 1e-12 48.8 0.0 2e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Asp PF00026.18 EIE76760.1 - 5.9e-61 206.4 3.2 8.8e-61 205.8 2.2 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIE76760.1 - 2.9e-09 37.1 1.1 1.3e-07 31.7 0.3 2.4 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EIE76760.1 - 8.3e-07 29.4 0.1 0.042 14.3 0.0 2.8 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 EIE76760.1 - 0.00029 20.4 0.3 0.0034 16.9 0.2 2.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal GP11 PF08677.5 EIE76760.1 - 0.16 11.1 2.8 2.4 7.2 0.0 2.7 3 0 0 3 3 3 0 GP11 baseplate wedge protein DDE_3 PF13358.1 EIE76761.1 - 1.7e-11 44.0 0.0 1.9e-11 43.9 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-Di19 PF05605.7 EIE76763.1 - 2.2e-06 27.6 5.4 0.018 15.1 0.1 2.1 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 EIE76763.1 - 1.2e-05 25.3 4.8 0.062 13.6 0.1 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 EIE76763.1 - 0.0024 17.9 5.9 0.083 13.0 4.0 2.1 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 EIE76763.1 - 0.0035 17.5 4.5 0.55 10.6 0.1 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-FCS PF06467.9 EIE76763.1 - 0.0064 16.1 2.1 1.8 8.2 0.1 2.3 2 0 0 2 2 2 2 MYM-type Zinc finger with FCS sequence motif zf-C2H2_jaz PF12171.3 EIE76763.1 - 0.012 15.7 0.4 0.012 15.7 0.3 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DUF4187 PF13821.1 EIE76763.1 - 0.014 15.0 2.9 0.048 13.2 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) NinG PF05766.7 EIE76763.1 - 0.057 13.1 2.4 0.28 10.8 0.1 2.0 2 0 0 2 2 2 0 Bacteriophage Lambda NinG protein ComK PF06338.6 EIE76763.1 - 0.12 11.7 0.3 0.18 11.2 0.2 1.2 1 0 0 1 1 1 0 ComK protein Thioredoxin_3 PF13192.1 EIE76763.1 - 0.15 11.8 0.8 0.26 11.1 0.0 1.8 2 0 0 2 2 2 0 Thioredoxin domain DUF629 PF04780.7 EIE76763.1 - 0.81 8.1 5.0 5.1 5.5 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF629) NAD_binding_2 PF03446.10 EIE76764.1 - 1.3e-28 99.9 0.1 2.1e-28 99.2 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EIE76764.1 - 1.8e-09 37.7 0.0 3.4e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.14 EIE76764.1 - 1.8e-07 30.4 0.0 3.5e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EIE76764.1 - 3.3e-07 30.6 0.1 1.2e-06 28.8 0.0 2.0 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 EIE76764.1 - 7.9e-05 22.7 0.3 0.00032 20.7 0.1 2.0 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.9 EIE76764.1 - 0.00031 20.1 0.8 0.038 13.3 0.2 2.5 1 1 1 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EIE76764.1 - 0.00033 20.4 0.5 0.0013 18.4 0.3 1.9 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_3 PF03447.11 EIE76764.1 - 0.00041 20.7 0.1 0.0011 19.4 0.1 1.8 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain ApbA PF02558.11 EIE76764.1 - 0.01 15.2 0.1 0.023 14.1 0.1 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GFO_IDH_MocA PF01408.17 EIE76764.1 - 0.013 16.0 0.1 0.037 14.5 0.1 1.8 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.19 EIE76764.1 - 0.087 13.1 0.0 0.29 11.4 0.0 1.9 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain DUF3906 PF13046.1 EIE76765.1 - 0.071 12.7 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3906) VWD PF00094.20 EIE76765.1 - 0.076 13.1 1.6 0.097 12.8 1.1 1.2 1 0 0 1 1 1 0 von Willebrand factor type D domain SMC_hinge PF06470.8 EIE76766.1 - 0.051 13.5 0.1 0.057 13.3 0.0 1.1 1 0 0 1 1 1 0 SMC proteins Flexible Hinge Domain TCTP PF00838.12 EIE76766.1 - 0.12 12.3 0.1 0.12 12.3 0.1 1.0 1 0 0 1 1 1 0 Translationally controlled tumour protein WSN PF02206.13 EIE76767.1 - 0.0078 15.9 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function G-gamma PF00631.17 EIE76768.1 - 5.6e-14 51.6 0.0 2.3e-13 49.7 0.0 2.1 2 0 0 2 2 2 1 GGL domain ERCC4 PF02732.10 EIE76768.1 - 6.8e-08 32.3 0.2 1.6e-06 27.9 0.0 2.5 2 0 0 2 2 2 1 ERCC4 domain RVT_1 PF00078.22 EIE76769.1 - 1e-31 109.9 0.0 1.9e-31 109.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.18 EIE76769.1 - 1.4e-09 38.2 0.6 3e-09 37.1 0.4 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EIE76769.1 - 7.4e-07 28.7 0.0 2.3e-06 27.1 0.0 2.0 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase zf-CCHC_6 PF15288.1 EIE76769.1 - 0.065 12.9 8.7 0.032 13.8 1.1 2.9 3 0 0 3 3 3 0 Zinc knuckle zf-CCHC PF00098.18 EIE76769.1 - 0.65 10.0 20.0 0.03 14.2 3.2 3.6 3 0 0 3 3 3 0 Zinc knuckle Lar_restr_allev PF14354.1 EIE76769.1 - 9.4 6.6 8.5 58 4.1 2.7 2.8 2 1 0 2 2 2 0 Restriction alleviation protein Lar OrfB_Zn_ribbon PF07282.6 EIE76770.1 - 2.3e-08 33.5 0.1 5.6e-08 32.3 0.1 1.6 1 0 0 1 1 1 1 Putative transposase DNA-binding domain DDE_3 PF13358.1 EIE76771.1 - 0.001 18.8 0.2 0.0027 17.4 0.1 1.9 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE76771.1 - 0.017 15.2 0.1 0.29 11.2 0.0 2.8 2 0 0 2 2 2 0 Transposase Vsr PF03852.10 EIE76771.1 - 0.044 13.4 0.0 0.14 11.7 0.0 1.9 1 0 0 1 1 1 0 DNA mismatch endonuclease Vsr Arm PF00514.18 EIE76772.1 - 7.6e-92 298.3 15.8 1.8e-13 49.7 0.0 8.6 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EIE76772.1 - 7.5e-30 103.0 1.1 1.7e-09 37.8 0.0 6.2 2 1 5 7 7 7 6 HEAT repeats HEAT_EZ PF13513.1 EIE76772.1 - 1.6e-23 82.5 6.3 6.9e-07 29.5 0.0 7.3 6 2 2 8 8 8 5 HEAT-like repeat HEAT PF02985.17 EIE76772.1 - 1.2e-19 68.5 6.2 7.7e-05 22.4 0.0 7.3 7 1 0 7 7 7 5 HEAT repeat IBB PF01749.15 EIE76772.1 - 1.8e-18 66.5 7.8 3.3e-18 65.6 5.4 1.5 1 0 0 1 1 1 1 Importin beta binding domain Arm_2 PF04826.8 EIE76772.1 - 2.3e-10 40.0 0.5 0.011 14.8 0.1 4.1 2 1 2 4 4 4 3 Armadillo-like Adaptin_N PF01602.15 EIE76772.1 - 1.3e-07 30.3 0.0 3.5e-06 25.6 0.0 2.5 1 1 0 1 1 1 1 Adaptin N terminal region V-ATPase_H_C PF11698.3 EIE76772.1 - 9.6e-06 25.5 0.1 0.38 10.6 0.0 4.6 2 1 1 4 4 4 1 V-ATPase subunit H Proteasom_PSMB PF10508.4 EIE76772.1 - 0.00021 19.7 2.0 0.002 16.4 0.0 2.8 3 0 0 3 3 3 1 Proteasome non-ATPase 26S subunit HEAT_PBS PF03130.11 EIE76772.1 - 0.0045 17.3 0.1 2.4 8.8 0.0 4.2 3 0 0 3 3 3 1 PBS lyase HEAT-like repeat RICTOR_V PF14668.1 EIE76772.1 - 0.015 15.2 6.3 1.3 9.0 0.1 4.7 2 2 4 6 6 6 0 Rapamycin-insensitive companion of mTOR, domain 5 DUF3731 PF12531.3 EIE76772.1 - 0.13 11.7 2.3 0.63 9.5 0.0 2.8 2 1 1 3 3 3 0 DNA-K related protein DUF2421 PF10334.4 EIE76774.1 - 2.7e-23 82.7 0.3 5.9e-23 81.6 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2421) TPT PF03151.11 EIE76774.1 - 1.9e-14 53.5 4.1 1.9e-14 53.5 2.8 3.2 2 1 1 3 3 3 1 Triose-phosphate Transporter family UAA PF08449.6 EIE76774.1 - 1e-08 34.5 17.4 2.4e-08 33.2 12.1 1.6 1 0 0 1 1 1 1 UAA transporter family DUF2422 PF10337.4 EIE76774.1 - 3.5e-05 22.8 11.9 0.016 14.0 0.5 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF2422) ALMT PF11744.3 EIE76774.1 - 0.00027 19.7 0.8 0.00027 19.7 0.5 2.2 2 1 0 2 2 2 1 Aluminium activated malate transporter Asp PF00026.18 EIE76775.1 - 3.4e-59 200.6 10.6 1.5e-53 182.1 3.4 2.1 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIE76775.1 - 2.4e-07 30.8 2.1 0.02 14.8 0.3 3.9 2 2 1 3 3 3 2 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EIE76775.1 - 0.00042 19.8 0.1 0.0013 18.3 0.1 1.8 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 EIE76775.1 - 0.00056 20.3 1.1 1.6 9.3 0.0 3.2 2 1 0 2 2 2 2 Aspartyl protease ArfGap PF01412.13 EIE76776.1 - 1.2e-32 112.1 1.8 1.2e-32 112.1 1.2 2.6 2 1 0 2 2 2 1 Putative GTPase activating protein for Arf Paired_CXXCH_1 PF09699.5 EIE76776.1 - 0.17 11.4 0.2 0.17 11.4 0.1 2.0 2 0 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) DUF3128 PF11326.3 EIE76777.1 - 3.4e-18 65.5 3.4 3.4e-18 65.5 2.3 1.5 1 1 1 2 2 2 1 Protein of unknown function (DUF3128) DUF3615 PF12274.3 EIE76777.1 - 0.0068 16.7 2.1 0.0068 16.7 1.4 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF3615) Cdd1 PF11731.3 EIE76777.1 - 0.085 12.7 0.9 0.14 12.1 0.6 1.3 1 0 0 1 1 1 0 Pathogenicity locus LSM PF01423.17 EIE76778.1 - 1.6e-17 62.8 1.8 2.3e-17 62.3 1.3 1.2 1 0 0 1 1 1 1 LSM domain Gemin7 PF11095.3 EIE76778.1 - 0.018 14.7 0.1 0.025 14.3 0.1 1.2 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) Flag1_repress PF03614.8 EIE76778.1 - 0.053 13.0 0.1 0.055 13.0 0.0 1.1 1 0 0 1 1 1 0 Repressor of phase-1 flagellin BPL_C PF02237.12 EIE76778.1 - 0.074 12.7 0.1 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain Phosducin PF02114.11 EIE76779.1 - 7.6e-20 70.7 0.4 1e-19 70.3 0.3 1.2 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.15 EIE76779.1 - 0.00016 21.3 0.1 0.00029 20.4 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin RRS1 PF04939.7 EIE76779.1 - 0.011 15.2 0.5 0.019 14.4 0.3 1.4 1 0 0 1 1 1 0 Ribosome biogenesis regulatory protein (RRS1) E1_DerP2_DerF2 PF02221.10 EIE76780.1 - 1.2e-18 67.6 0.0 1.5e-18 67.3 0.0 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 EIE76780.1 - 0.0005 20.1 0.0 0.00064 19.7 0.0 1.1 1 0 0 1 1 1 1 ML-like domain Polysacc_deac_1 PF01522.16 EIE76781.1 - 1.4e-29 102.2 0.2 2.9e-29 101.2 0.1 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Pirin PF02678.11 EIE76783.1 - 1.3e-32 111.8 0.1 2.3e-32 111.0 0.0 1.4 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.8 EIE76783.1 - 8e-31 106.1 0.0 3.1e-29 101.1 0.0 2.4 3 0 0 3 3 3 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 EIE76783.1 - 0.011 15.2 2.8 0.026 14.0 0.3 2.5 3 0 0 3 3 3 0 Cupin domain Adeno_E3A PF05248.7 EIE76783.1 - 0.096 12.7 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Adenovirus E3A SET PF00856.23 EIE76784.1 - 9.9e-17 61.7 0.2 2.7e-16 60.3 0.2 1.7 1 1 0 1 1 1 1 SET domain TruD PF01142.13 EIE76784.1 - 0.014 14.0 0.3 0.022 13.4 0.2 1.2 1 0 0 1 1 1 0 tRNA pseudouridine synthase D (TruD) Nucleoplasmin PF03066.10 EIE76784.1 - 0.062 12.8 9.6 0.13 11.8 6.6 1.4 1 0 0 1 1 1 0 Nucleoplasmin FAM176 PF14851.1 EIE76784.1 - 0.14 11.8 7.8 0.037 13.7 2.5 2.0 2 0 0 2 2 2 0 FAM176 family Cytomega_UL84 PF06284.6 EIE76784.1 - 0.44 8.9 3.5 0.67 8.2 2.4 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Myc_N PF01056.13 EIE76784.1 - 0.47 9.5 7.2 0.85 8.7 5.0 1.3 1 0 0 1 1 1 0 Myc amino-terminal region Radial_spoke PF04712.7 EIE76784.1 - 0.64 8.7 10.5 1 8.0 7.3 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein Daxx PF03344.10 EIE76784.1 - 0.9 7.9 9.8 1.5 7.2 6.8 1.3 1 0 0 1 1 1 0 Daxx Family BSP_II PF05432.6 EIE76784.1 - 1.2 8.3 16.3 1.9 7.7 11.3 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) CENP-B_dimeris PF09026.5 EIE76784.1 - 2.2 8.5 10.7 4.9 7.4 7.4 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Cyclin_N PF00134.18 EIE76785.1 - 0.00054 19.5 0.1 0.00062 19.3 0.1 1.0 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 EIE76785.1 - 0.1 12.9 0.1 0.13 12.6 0.1 1.1 1 0 0 1 1 1 0 Cyclin Myb_DNA-bind_6 PF13921.1 EIE76787.1 - 2.5e-05 24.2 0.0 4.5e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EIE76787.1 - 0.0082 16.1 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain GPI-anchored PF10342.4 EIE76788.1 - 2.8e-07 30.9 0.0 4.1e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Ribosomal_L6e PF01159.14 EIE76789.1 - 1.9e-36 124.6 0.3 1.9e-36 124.6 0.2 1.6 2 0 0 2 2 2 1 Ribosomal protein L6e Ribosomal_L6e_N PF03868.10 EIE76789.1 - 3.3e-11 42.9 1.6 3.3e-11 42.9 1.1 2.2 2 0 0 2 2 2 1 Ribosomal protein L6, N-terminal domain KOW PF00467.24 EIE76789.1 - 0.004 16.8 0.3 0.011 15.4 0.0 1.9 2 0 0 2 2 2 1 KOW motif PAT1 PF09770.4 EIE76790.1 - 4.5e-139 465.1 37.1 5.1e-131 438.4 15.9 2.4 1 1 1 2 2 2 2 Topoisomerase II-associated protein PAT1 Mt_ATP-synt_D PF05873.7 EIE76791.1 - 5.6e-18 65.0 6.7 7.3e-18 64.7 4.7 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) PEP-utilisers_N PF05524.8 EIE76791.1 - 0.00043 20.0 3.6 0.033 14.0 0.4 2.1 1 1 1 2 2 2 1 PEP-utilising enzyme, N-terminal Peptidase_M75 PF09375.5 EIE76791.1 - 0.011 15.0 2.7 0.013 14.8 1.2 1.5 1 1 0 1 1 1 0 Imelysin TMF_TATA_bd PF12325.3 EIE76791.1 - 0.014 15.1 1.0 0.014 15.1 0.7 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Vps51 PF08700.6 EIE76791.1 - 0.017 14.9 6.0 0.33 10.8 0.4 2.4 1 1 1 2 2 2 0 Vps51/Vps67 AAA_13 PF13166.1 EIE76791.1 - 0.022 13.2 11.6 0.027 12.9 8.1 1.0 1 0 0 1 1 1 0 AAA domain Cypo_polyhedrin PF05865.6 EIE76791.1 - 0.023 13.9 0.0 0.025 13.8 0.0 1.1 1 0 0 1 1 1 0 Cypovirus polyhedrin protein Baculo_PEP_C PF04513.7 EIE76791.1 - 0.038 13.7 2.8 0.053 13.3 1.9 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4613 PF15390.1 EIE76791.1 - 0.052 11.7 3.7 0.061 11.4 2.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Peptidase_S64 PF08192.6 EIE76791.1 - 0.07 11.4 5.0 0.073 11.4 3.4 1.0 1 0 0 1 1 1 0 Peptidase family S64 DUF1678 PF07913.6 EIE76791.1 - 0.072 12.6 0.2 0.093 12.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1678) Laminin_II PF06009.7 EIE76791.1 - 0.074 12.8 11.6 0.034 13.8 1.6 2.4 1 1 2 3 3 3 0 Laminin Domain II DUF1845 PF08900.6 EIE76791.1 - 0.077 12.2 2.3 0.091 12.0 0.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1845) Phage_GP20 PF06810.6 EIE76791.1 - 0.088 12.2 12.7 0.51 9.7 7.2 2.0 1 1 1 2 2 2 0 Phage minor structural protein GP20 SPX PF03105.14 EIE76791.1 - 0.098 12.4 7.0 0.18 11.5 4.8 1.4 1 1 0 1 1 1 0 SPX domain Nitrophorin PF02087.10 EIE76791.1 - 0.1 12.3 1.1 0.18 11.5 0.8 1.4 1 1 0 1 1 1 0 Nitrophorin Peptidase_S74 PF13884.1 EIE76791.1 - 0.1 12.7 0.3 0.68 10.0 0.1 2.2 1 1 1 2 2 2 0 Chaperone of endosialidase TMPIT PF07851.8 EIE76791.1 - 0.11 11.5 7.0 0.14 11.2 4.6 1.4 1 1 0 1 1 1 0 TMPIT-like protein HTH_5 PF01022.15 EIE76791.1 - 0.12 12.1 0.2 0.42 10.3 0.0 2.0 2 0 0 2 2 1 0 Bacterial regulatory protein, arsR family DUF327 PF03885.8 EIE76791.1 - 0.16 11.8 6.6 0.95 9.2 4.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF327) WXG100 PF06013.7 EIE76791.1 - 0.27 11.2 3.2 2.2 8.3 0.8 2.5 2 1 0 2 2 2 0 Proteins of 100 residues with WXG COG2 PF06148.6 EIE76791.1 - 0.28 11.0 6.8 0.51 10.2 4.1 1.8 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF148 PF02520.12 EIE76791.1 - 0.31 10.8 10.8 0.17 11.7 5.5 1.9 1 1 0 1 1 1 0 Domain of unknown function DUF148 V_ATPase_I PF01496.14 EIE76791.1 - 0.33 8.7 9.1 0.64 7.8 6.3 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Fib_alpha PF08702.5 EIE76791.1 - 0.39 10.8 8.8 0.58 10.2 6.1 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Helicase_IV_N PF12462.3 EIE76791.1 - 0.41 10.2 4.2 8.6 5.9 2.8 2.3 1 1 0 1 1 1 0 DNA helicase IV / RNA helicase N terminal DUF2937 PF11157.3 EIE76791.1 - 0.41 9.9 2.8 0.41 9.9 0.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2937) DUF4600 PF15372.1 EIE76791.1 - 0.41 10.8 7.6 4.5 7.5 1.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4600) CDC37_N PF03234.9 EIE76791.1 - 0.56 10.5 6.8 0.82 9.9 4.7 1.3 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding DUF1664 PF07889.7 EIE76791.1 - 0.56 10.0 6.0 0.61 9.8 2.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Prominin PF05478.6 EIE76791.1 - 0.61 7.5 6.4 0.68 7.4 4.4 1.1 1 0 0 1 1 1 0 Prominin DUF2802 PF10975.3 EIE76791.1 - 0.66 9.7 4.5 1.7 8.4 1.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) ApoLp-III PF07464.6 EIE76791.1 - 0.72 9.8 12.6 1.7 8.6 8.3 1.7 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DUF4140 PF13600.1 EIE76791.1 - 0.99 9.8 9.3 0.3 11.5 1.4 2.5 1 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF948 PF06103.6 EIE76791.1 - 1.1 9.1 6.4 2.3 8.1 2.3 2.5 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF948) Spc7 PF08317.6 EIE76791.1 - 1.2 7.7 12.2 2.2 6.8 8.4 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein tRNA-synt_His PF13393.1 EIE76791.1 - 1.3 8.0 4.4 2.9 6.8 3.0 1.5 1 1 0 1 1 1 0 Histidyl-tRNA synthetase DUF2408 PF10303.4 EIE76791.1 - 1.4 9.0 6.7 7.1 6.7 4.5 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) FlaC_arch PF05377.6 EIE76791.1 - 1.6 8.6 9.6 12 5.8 0.3 3.1 1 1 0 2 2 2 0 Flagella accessory protein C (FlaC) BLOC1_2 PF10046.4 EIE76791.1 - 2.2 8.4 10.3 0.71 10.0 2.7 2.5 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 IncA PF04156.9 EIE76791.1 - 2.2 7.8 11.5 45 3.5 8.0 2.1 1 1 0 1 1 1 0 IncA protein Adeno_PIX PF03955.9 EIE76791.1 - 2.2 8.8 4.8 2.7 8.5 1.3 2.1 1 1 1 2 2 2 0 Adenovirus hexon-associated protein (IX) Ribosomal_L29 PF00831.18 EIE76791.1 - 2.5 7.8 7.5 2 8.1 1.4 2.5 2 1 0 2 2 2 0 Ribosomal L29 protein Uso1_p115_C PF04871.8 EIE76791.1 - 2.7 7.9 9.5 0.76 9.7 4.3 1.7 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF1090 PF06476.7 EIE76791.1 - 3.5 7.3 11.3 8.5 6.0 3.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1090) TPR_MLP1_2 PF07926.7 EIE76791.1 - 3.7 7.2 13.3 87 2.8 8.8 2.2 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Med9 PF07544.8 EIE76791.1 - 6.1 6.6 7.9 18 5.1 2.9 2.8 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 LUC7 PF03194.10 EIE76791.1 - 6.4 6.2 7.7 3.9 6.9 3.8 1.7 1 1 1 2 2 2 0 LUC7 N_terminus DivIC PF04977.10 EIE76791.1 - 6.5 6.3 9.3 2.3 7.7 1.6 2.7 2 1 0 2 2 2 0 Septum formation initiator NPV_P10 PF05531.7 EIE76791.1 - 6.5 7.0 12.9 41 4.5 5.7 3.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Syntaxin PF00804.20 EIE76791.1 - 9.5 6.4 10.7 63 3.8 7.4 2.1 1 1 0 1 1 1 0 Syntaxin GPI-anchored PF10342.4 EIE76793.1 - 3e-08 34.0 0.4 4.5e-08 33.4 0.2 1.3 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family AIG2 PF06094.7 EIE76794.1 - 0.00024 21.5 0.0 0.00025 21.4 0.0 1.1 1 0 0 1 1 1 1 AIG2-like family Seipin PF06775.9 EIE76795.1 - 1.2e-43 148.9 8.3 5.5e-41 140.2 5.8 2.2 1 1 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) DUF1113 PF06541.6 EIE76795.1 - 0.0071 16.1 0.4 0.0071 16.1 0.3 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1113) Haemocyan_bet_s PF14830.1 EIE76795.1 - 0.042 13.5 0.0 0.094 12.4 0.0 1.5 1 0 0 1 1 1 0 Haemocyanin beta-sandwich Ribosomal_S8 PF00410.14 EIE76796.1 - 7.4e-27 93.7 0.1 9.2e-27 93.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 Pescadillo_N PF06732.6 EIE76797.1 - 5.3e-122 406.4 3.9 7e-122 406.0 2.7 1.1 1 0 0 1 1 1 1 Pescadillo N-terminus BRCT PF00533.21 EIE76797.1 - 2.8e-05 24.1 0.0 6.6e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF3682 PF12446.3 EIE76797.1 - 3.1 8.0 7.0 5.2 7.3 4.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Aldedh PF00171.17 EIE76798.1 - 1.4e-94 317.1 0.0 1.7e-94 316.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF2984 PF11203.3 EIE76799.1 - 0.051 13.6 0.0 0.094 12.8 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2984) MULE PF10551.4 EIE76800.1 - 1.8e-09 37.6 0.1 2.1e-08 34.2 0.0 2.4 2 0 0 2 2 2 1 MULE transposase domain DDE_Tnp_IS240 PF13610.1 EIE76800.1 - 0.0031 17.5 0.0 0.041 13.8 0.0 2.7 2 1 0 2 2 2 1 DDE domain SWIM PF04434.12 EIE76800.1 - 0.013 14.9 0.5 0.013 14.9 0.3 2.2 2 0 0 2 2 2 0 SWIM zinc finger fn1 PF00039.13 EIE76800.1 - 0.015 15.0 0.4 0.41 10.5 0.1 2.8 2 0 0 2 2 2 0 Fibronectin type I domain AIP3 PF03915.8 EIE76802.1 - 2.7e-55 187.9 44.4 7.3e-51 173.4 18.8 3.7 1 1 2 3 3 3 2 Actin interacting protein 3 HALZ PF02183.13 EIE76802.1 - 0.078 12.7 5.2 0.95 9.2 0.0 3.8 3 0 0 3 3 3 0 Homeobox associated leucine zipper Ubiq_cyt_C_chap PF03981.7 EIE76802.1 - 0.087 12.6 2.9 0.24 11.2 0.4 2.6 2 1 0 2 2 2 0 Ubiquinol-cytochrome C chaperone DUF1539 PF07560.6 EIE76802.1 - 3.5 7.5 19.1 1.2 9.0 1.2 3.6 2 1 1 3 3 3 0 Domain of Unknown Function (DUF1539) RPE65 PF03055.10 EIE76803.1 - 7.6e-97 324.8 0.4 9.2e-97 324.6 0.3 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Ycf9 PF01737.12 EIE76804.1 - 0.008 15.6 0.1 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 YCF9 Peptidase_M18 PF02127.10 EIE76806.1 - 0.072 11.5 0.0 0.078 11.4 0.0 1.0 1 0 0 1 1 1 0 Aminopeptidase I zinc metalloprotease (M18) zf-CCHC PF00098.18 EIE76807.1 - 6e-05 22.7 10.9 0.0011 18.7 1.3 2.3 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 EIE76807.1 - 0.0016 18.0 5.4 0.017 14.7 0.1 2.5 2 0 0 2 2 2 2 Zinc knuckle Macin PF14865.1 EIE76807.1 - 0.036 14.1 1.5 0.2 11.7 1.0 2.2 1 1 1 2 2 2 0 Macin zf-CCHC_3 PF13917.1 EIE76807.1 - 0.56 9.9 7.1 4.9 6.9 0.1 2.4 1 1 1 2 2 2 0 Zinc knuckle RVT_1 PF00078.22 EIE76808.1 - 1.6e-33 115.8 0.0 3.3e-33 114.8 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.1 EIE76808.1 - 0.00015 22.0 1.6 0.00055 20.1 1.1 2.0 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase HEAT PF02985.17 EIE76809.1 - 1.3e-08 34.2 0.2 0.029 14.4 0.0 4.8 5 0 0 5 5 5 2 HEAT repeat DUF4203 PF13886.1 EIE76809.1 - 2.6e-08 33.5 24.0 6.7e-08 32.2 15.6 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF4203) Pkinase PF00069.20 EIE76809.1 - 9.9e-05 21.6 0.0 0.00017 20.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Cnd1 PF12717.2 EIE76809.1 - 0.00028 20.7 0.3 0.3 10.9 0.0 3.1 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EIE76809.1 - 0.00069 19.8 0.0 0.0063 16.7 0.0 2.5 1 1 2 3 3 3 2 HEAT repeats Pkinase_Tyr PF07714.12 EIE76809.1 - 0.0012 17.9 0.0 0.002 17.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_EZ PF13513.1 EIE76809.1 - 0.0023 18.3 0.2 3.6 8.2 0.0 3.5 3 1 1 4 4 4 1 HEAT-like repeat Kinase-like PF14531.1 EIE76809.1 - 0.094 11.6 0.0 0.16 10.8 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Hexokinase_2 PF03727.11 EIE76810.1 - 2.4e-77 259.4 0.0 3.8e-77 258.7 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EIE76810.1 - 8.2e-67 224.5 0.1 1.4e-66 223.7 0.0 1.3 1 0 0 1 1 1 1 Hexokinase DNA_pol_B PF00136.16 EIE76811.1 - 4.6e-93 312.5 0.2 4.6e-93 312.5 0.1 1.5 2 0 0 2 2 2 1 DNA polymerase family B zf-C4pol PF14260.1 EIE76811.1 - 8.2e-14 51.3 7.0 1.6e-13 50.4 4.9 1.5 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta RecR PF02132.10 EIE76811.1 - 0.0087 15.4 3.1 0.0087 15.4 2.1 2.1 2 0 0 2 2 2 1 RecR protein UPF0137 PF03677.8 EIE76811.1 - 0.017 14.6 0.0 0.051 13.1 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0137) DDE_3 PF13358.1 EIE76814.1 - 1.6e-13 50.6 0.2 2.1e-13 50.2 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4164 PF13747.1 EIE76814.1 - 0.012 15.6 3.0 0.017 15.2 2.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) Toprim_N PF08275.6 EIE76814.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 DNA primase catalytic core, N-terminal domain PSK_trans_fac PF07704.6 EIE76814.1 - 0.34 11.6 3.0 0.76 10.4 1.9 1.7 1 1 1 2 2 2 0 Rv0623-like transcription factor PIG-P PF08510.7 EIE76818.1 - 0.12 12.0 0.5 0.13 11.9 0.4 1.2 1 0 0 1 1 1 0 PIG-P Phage_integrase PF00589.17 EIE76820.1 - 0.0001 22.0 0.8 0.0012 18.5 0.2 2.4 2 1 1 3 3 3 1 Phage integrase family DUF2421 PF10334.4 EIE76822.1 - 0.011 15.3 0.1 0.02 14.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2421) Med8 PF10232.4 EIE76822.1 - 0.2 11.1 4.1 0.08 12.4 0.6 1.8 1 1 1 2 2 2 0 Mediator of RNA polymerase II transcription complex subunit 8 DDE_3 PF13358.1 EIE76824.1 - 3e-13 49.7 0.9 6.1e-13 48.7 0.6 1.7 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE76824.1 - 7.9e-10 38.6 2.1 1.5e-09 37.7 1.5 1.4 1 0 0 1 1 1 1 Transposase DUF4164 PF13747.1 EIE76824.1 - 0.031 14.3 2.8 0.031 14.3 2.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) DUF273 PF03314.9 EIE76824.1 - 0.17 11.1 2.1 0.81 8.9 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function, DUF273 PSK_trans_fac PF07704.6 EIE76824.1 - 2.5 8.8 6.7 1.2 9.8 1.7 2.3 2 1 0 2 2 2 0 Rv0623-like transcription factor HTH_29 PF13551.1 EIE76825.1 - 8.1e-06 25.9 0.0 1.7e-05 24.9 0.0 1.5 1 1 1 2 2 2 1 Winged helix-turn helix Terminase_5 PF06056.7 EIE76825.1 - 2e-05 24.0 0.3 4.7e-05 22.8 0.0 1.7 2 0 0 2 2 2 1 Putative ATPase subunit of terminase (gpP-like) HTH_32 PF13565.1 EIE76825.1 - 2.5e-05 24.9 0.0 0.00028 21.6 0.0 2.1 1 1 1 2 2 2 1 Homeodomain-like domain Sigma70_r4_2 PF08281.7 EIE76825.1 - 0.00024 20.5 0.0 0.00059 19.2 0.0 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_Tnp_1 PF01527.15 EIE76825.1 - 0.0005 19.9 0.1 0.00079 19.3 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_17 PF12728.2 EIE76825.1 - 0.0021 18.2 0.0 0.089 13.0 0.0 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.1 EIE76825.1 - 0.0023 17.5 0.0 0.0062 16.1 0.0 1.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.1 EIE76825.1 - 0.039 13.9 0.0 0.099 12.6 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain DivIC PF04977.10 EIE76826.1 - 0.0021 17.4 2.0 0.0057 16.1 1.4 1.6 1 0 0 1 1 1 1 Septum formation initiator Lebercilin PF15619.1 EIE76826.1 - 0.012 15.0 2.6 0.012 15.0 1.8 1.5 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Herpes_BLRF2 PF05812.7 EIE76826.1 - 0.016 15.0 0.1 0.033 14.0 0.1 1.5 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein SlyX PF04102.7 EIE76826.1 - 0.062 13.6 0.8 0.15 12.4 0.5 1.7 1 0 0 1 1 1 0 SlyX Cep57_CLD_2 PF14197.1 EIE76826.1 - 0.93 9.4 4.1 1 9.3 1.7 1.9 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 DivIC PF04977.10 EIE76827.1 - 0.004 16.5 0.8 0.0075 15.7 0.5 1.3 1 0 0 1 1 1 1 Septum formation initiator SlyX PF04102.7 EIE76827.1 - 0.084 13.2 0.4 0.084 13.2 0.3 1.8 2 0 0 2 2 2 0 SlyX TMF_TATA_bd PF12325.3 EIE76827.1 - 0.14 11.8 0.2 0.26 11.0 0.1 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Gag_spuma PF03276.9 EIE76827.1 - 4.5 5.4 11.5 6 5.0 8.0 1.1 1 0 0 1 1 1 0 Spumavirus gag protein Phage_integrase PF00589.17 EIE76828.1 - 2.8e-06 27.1 0.0 4e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family RVT_1 PF00078.22 EIE76828.1 - 0.0071 15.7 0.4 0.018 14.4 0.3 1.8 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ERF PF04404.7 EIE76828.1 - 0.019 14.4 0.3 0.033 13.7 0.2 1.3 1 0 0 1 1 1 0 ERF superfamily Pro_dh-DNA_bdg PF14850.1 EIE76828.1 - 0.1 12.7 0.2 0.17 12.0 0.1 1.3 1 0 0 1 1 1 0 DNA-binding domain of Proline dehydrogenase p450 PF00067.17 EIE76829.1 - 7.8e-66 222.4 0.0 6.1e-48 163.4 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 UPF0052 PF01933.13 EIE76830.1 - 1.4e-52 178.9 0.0 1.7e-52 178.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 MTBP_mid PF14919.1 EIE76831.1 - 0.048 12.3 0.0 0.052 12.2 0.0 1.1 1 0 0 1 1 1 0 MDM2-binding DDE_3 PF13358.1 EIE76833.1 - 3.5e-07 30.0 0.0 2.7e-06 27.1 0.0 2.2 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_29 PF13551.1 EIE76833.1 - 0.00018 21.6 0.0 0.00038 20.5 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EIE76833.1 - 0.011 15.3 0.0 0.032 13.8 0.0 1.8 1 0 0 1 1 1 0 Homeodomain-like domain WHEP-TRS PF00458.15 EIE76833.1 - 0.11 12.1 0.0 0.3 10.8 0.0 1.6 1 0 0 1 1 1 0 WHEP-TRS domain MTBP_mid PF14919.1 EIE76834.1 - 0.048 12.3 0.0 0.052 12.2 0.0 1.1 1 0 0 1 1 1 0 MDM2-binding DUF1253 PF06862.7 EIE76835.1 - 5.9e-139 463.2 9.0 5.9e-139 463.2 6.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1253) DUF2895 PF11444.3 EIE76835.1 - 0.012 14.8 0.0 0.03 13.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2895) Methyltransf_12 PF08242.7 EIE76835.1 - 0.061 13.7 1.6 7.9 7.0 0.0 4.1 3 1 0 3 3 3 0 Methyltransferase domain Sec7 PF01369.15 EIE76836.1 - 1.4e-27 96.6 2.9 3.1e-27 95.4 2.0 1.6 1 0 0 1 1 1 1 Sec7 domain PP2C PF00481.16 EIE76837.1 - 9.1e-75 251.3 0.0 1.1e-74 251.0 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EIE76837.1 - 5.2e-06 26.3 0.0 0.014 15.0 0.0 2.1 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 EIE76837.1 - 0.00013 21.4 0.0 0.00041 19.8 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C NmrA PF05368.8 EIE76838.1 - 3.1e-11 42.9 0.0 4.1e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EIE76838.1 - 1.3e-06 28.5 0.0 2e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding HTH_Tnp_Tc3_2 PF01498.13 EIE76841.1 - 4.3e-05 23.4 0.0 7.7e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Transposase DUF3603 PF12227.3 EIE76843.1 - 0.087 11.9 0.0 0.2 10.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3603) Adenylsucc_synt PF00709.16 EIE76843.1 - 0.17 10.5 0.1 0.29 9.7 0.0 1.3 1 0 0 1 1 1 0 Adenylosuccinate synthetase Evr1_Alr PF04777.8 EIE76844.1 - 8.1e-13 48.0 0.5 8.1e-13 48.0 0.3 2.2 2 1 0 2 2 2 1 Erv1 / Alr family DIOX_N PF14226.1 EIE76845.1 - 1.1e-19 71.0 0.1 2.2e-19 70.0 0.1 1.5 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EIE76845.1 - 2.2e-16 59.9 0.0 3.9e-16 59.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily dCMP_cyt_deam_1 PF00383.17 EIE76846.1 - 2.1e-12 46.5 0.0 6e-12 45.1 0.0 1.7 1 1 1 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 EIE76846.1 - 4.1e-05 23.4 0.6 0.00049 19.9 0.4 2.1 1 1 0 1 1 1 1 Bd3614-like deaminase RAB3GAP2_N PF14655.1 EIE76848.1 - 0.061 12.3 4.6 0.058 12.3 3.2 1.0 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus BORG_CEP PF14957.1 EIE76848.1 - 0.087 13.7 1.7 0.093 13.6 1.2 1.0 1 0 0 1 1 1 0 Cdc42 effector DUF1071 PF06378.6 EIE76848.1 - 0.47 9.5 2.7 0.45 9.6 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1071) Pex14_N PF04695.8 EIE76848.1 - 2.2 8.3 9.0 2.2 8.3 6.2 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region NmrA PF05368.8 EIE76849.1 - 2.8e-10 39.8 0.0 3.9e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EIE76849.1 - 3e-06 27.3 0.0 5e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding CYSTM PF12734.2 EIE76851.1 - 4.4e-06 26.6 17.0 4.4e-06 26.6 11.8 1.7 2 1 0 2 2 2 1 Cysteine-rich TM module stress tolerance Pkinase PF00069.20 EIE76852.1 - 2.5e-60 203.8 0.0 2.8e-60 203.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE76852.1 - 1.9e-39 135.3 0.0 2.1e-39 135.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE76852.1 - 0.00032 19.7 0.0 0.00059 18.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EIE76852.1 - 0.0067 15.7 0.6 0.011 15.1 0.0 1.6 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 EIE76852.1 - 0.0076 16.0 0.0 0.023 14.4 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family WD40 PF00400.27 EIE76853.1 - 5.8e-53 174.9 16.8 5.8e-11 41.8 0.1 8.0 7 1 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.2 EIE76853.1 - 4.6e-10 39.0 1.4 8.4e-10 38.2 1.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIE76853.1 - 1.3e-09 37.4 1.7 2.6e-09 36.5 1.2 1.5 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 EIE76853.1 - 3.9e-07 28.5 5.8 0.039 12.0 0.3 4.7 3 2 1 4 4 4 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EIE76853.1 - 7.6e-05 21.6 4.1 3.3 6.3 0.1 4.7 3 2 1 4 4 4 2 Nup133 N terminal like PQQ_2 PF13360.1 EIE76853.1 - 0.0016 17.9 0.3 0.38 10.1 0.1 3.1 3 1 0 3 3 3 1 PQQ-like domain PRANC PF09372.5 EIE76853.1 - 0.026 14.4 0.1 0.06 13.3 0.1 1.5 1 0 0 1 1 1 0 PRANC domain PQQ_3 PF13570.1 EIE76853.1 - 0.032 14.5 0.2 29 5.1 0.0 3.7 4 0 0 4 4 4 0 PQQ-like domain PIF1 PF05970.9 EIE76854.1 - 1.8e-54 185.0 1.7 9.3e-46 156.4 0.1 3.6 2 1 1 3 3 3 2 PIF1-like helicase AAA_30 PF13604.1 EIE76854.1 - 4.7e-21 75.2 0.0 7.8e-21 74.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.9 EIE76854.1 - 2.7e-09 35.4 0.0 2.3e-05 22.3 0.0 2.3 2 0 0 2 2 2 2 Helicase AAA_22 PF13401.1 EIE76854.1 - 3.9e-07 30.2 0.0 8.7e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EIE76854.1 - 7.6e-06 26.1 0.1 1.4e-05 25.3 0.1 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) UvrD_C_2 PF13538.1 EIE76854.1 - 0.00022 21.3 0.0 0.00049 20.2 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain T2SE PF00437.15 EIE76854.1 - 0.00036 19.5 0.0 0.00062 18.7 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein Viral_helicase1 PF01443.13 EIE76854.1 - 0.0011 18.5 0.1 0.66 9.4 0.0 2.9 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 EIE76854.1 - 0.0016 18.1 0.0 0.0032 17.1 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 EIE76854.1 - 0.0017 18.4 0.2 0.014 15.4 0.0 2.3 3 0 0 3 3 3 1 AAA ATPase domain PhoH PF02562.11 EIE76854.1 - 0.011 14.9 0.0 0.031 13.5 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein ABC_tran PF00005.22 EIE76854.1 - 0.011 15.9 0.2 0.038 14.2 0.1 1.8 1 1 1 2 2 2 0 ABC transporter AAA_14 PF13173.1 EIE76854.1 - 0.016 15.1 0.0 0.049 13.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 EIE76854.1 - 0.027 13.6 0.0 0.043 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DUF2075 PF09848.4 EIE76854.1 - 0.028 13.3 0.1 0.076 11.9 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.1 EIE76854.1 - 0.03 13.9 0.0 4 6.9 0.0 2.3 1 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 EIE76854.1 - 0.046 13.1 0.0 9.9 5.5 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein Helicase_RecD PF05127.9 EIE76854.1 - 0.052 13.1 0.0 0.095 12.3 0.0 1.4 1 0 0 1 1 1 0 Helicase AAA_29 PF13555.1 EIE76854.1 - 0.063 12.8 0.0 0.17 11.4 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.21 EIE76854.1 - 0.11 11.9 0.0 0.29 10.6 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Arch_ATPase PF01637.13 EIE76854.1 - 0.13 11.9 0.4 0.57 9.8 0.2 2.0 1 1 0 1 1 1 0 Archaeal ATPase RRM_1 PF00076.17 EIE76855.1 - 1.5e-07 30.9 0.1 1.7e-07 30.7 0.1 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Root_cap PF06830.6 EIE76855.1 - 0.081 12.7 0.0 0.095 12.5 0.0 1.1 1 0 0 1 1 1 0 Root cap RRM_6 PF14259.1 EIE76855.1 - 0.081 12.9 0.1 0.099 12.6 0.0 1.1 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF883 PF05957.8 EIE76857.1 - 0.057 13.8 26.6 0.99 9.8 4.1 3.1 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF3951 PF13131.1 EIE76857.1 - 0.11 12.3 0.0 0.27 11.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3951) Apolipoprotein PF01442.13 EIE76857.1 - 0.24 10.8 11.7 4.1 6.8 8.1 2.4 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Arch_ATPase PF01637.13 EIE76857.1 - 0.46 10.1 4.0 4.8 6.8 2.7 2.0 1 1 0 1 1 1 0 Archaeal ATPase Borrelia_P83 PF05262.6 EIE76857.1 - 1.4 7.0 25.5 1.9 6.6 17.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DivIVA PF05103.8 EIE76857.1 - 8.7 6.4 28.0 17 5.5 6.1 2.7 1 1 1 2 2 2 0 DivIVA protein AAA PF00004.24 EIE76858.1 - 9.2e-42 142.3 0.0 2.5e-41 140.9 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EIE76858.1 - 5.1e-06 26.6 0.0 0.0005 20.2 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EIE76858.1 - 6.9e-06 25.8 0.1 4.9e-05 23.0 0.0 2.5 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EIE76858.1 - 6.5e-05 22.9 0.0 0.00016 21.6 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.9 EIE76858.1 - 0.00019 21.3 0.0 0.00069 19.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 EIE76858.1 - 0.00069 18.6 0.0 0.0012 17.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 EIE76858.1 - 0.0015 19.3 0.2 0.0048 17.7 0.1 2.0 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.7 EIE76858.1 - 0.0032 16.5 0.0 0.0064 15.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EIE76858.1 - 0.0032 17.1 0.1 0.0067 16.1 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 EIE76858.1 - 0.01 15.7 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EIE76858.1 - 0.011 14.8 0.0 0.019 14.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.1 EIE76858.1 - 0.012 15.4 0.0 0.025 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EIE76858.1 - 0.013 15.2 0.2 5.2 6.7 0.0 2.9 2 1 1 3 3 3 0 Archaeal ATPase AAA_14 PF13173.1 EIE76858.1 - 0.015 15.2 0.0 0.036 13.9 0.0 1.7 2 0 0 2 2 1 0 AAA domain Sigma54_activ_2 PF14532.1 EIE76858.1 - 0.016 15.2 0.0 0.038 14.0 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_3 PF07726.6 EIE76858.1 - 0.025 14.1 0.0 0.05 13.1 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) KaiC PF06745.8 EIE76858.1 - 0.025 13.6 0.1 1.4 8.0 0.0 2.4 2 0 0 2 2 2 0 KaiC RNA_helicase PF00910.17 EIE76858.1 - 0.03 14.4 0.0 0.08 13.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.12 EIE76858.1 - 0.031 13.6 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.1 EIE76858.1 - 0.035 14.4 0.0 0.12 12.7 0.0 2.0 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 EIE76858.1 - 0.037 12.7 0.0 0.078 11.6 0.0 1.5 1 0 0 1 1 1 0 TIP49 C-terminus Mg_chelatase PF01078.16 EIE76858.1 - 0.052 12.7 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 EIE76858.1 - 0.052 13.1 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EIE76858.1 - 0.079 12.4 0.0 0.2 11.1 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_25 PF13481.1 EIE76858.1 - 0.12 11.7 0.1 0.44 9.9 0.0 1.9 1 1 1 2 2 2 0 AAA domain TFIIE-A_C-term PF11521.3 EIE76859.1 - 0.00056 19.8 2.0 0.00056 19.8 1.4 3.4 2 1 2 4 4 4 1 C-terminal general transcription factor TFIIE alpha zf-H2C2_2 PF13465.1 EIE76859.1 - 0.025 14.8 0.9 0.35 11.2 0.0 2.3 2 0 0 2 2 2 0 Zinc-finger double domain C1_3 PF07649.7 EIE76859.1 - 0.044 13.8 1.9 0.35 10.9 0.2 2.2 2 0 0 2 2 2 0 C1-like domain TF_Zn_Ribbon PF08271.7 EIE76859.1 - 1.5 8.2 4.1 7.3 6.0 2.7 2.3 1 1 1 2 2 2 0 TFIIB zinc-binding Ribosomal_L11_N PF03946.9 EIE76861.1 - 2.2e-18 65.4 0.1 4.6e-18 64.4 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 EIE76861.1 - 1.7e-12 47.2 0.1 2.9e-12 46.5 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain IF2_N PF04760.10 EIE76861.1 - 0.055 13.1 0.1 0.4 10.3 0.0 2.3 1 1 1 2 2 2 0 Translation initiation factor IF-2, N-terminal region ADH_zinc_N PF00107.21 EIE76862.1 - 3.6e-19 68.5 0.5 5.4e-19 68.0 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIE76862.1 - 0.0003 20.5 0.1 0.0029 17.3 0.0 2.4 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Arrestin_N PF00339.24 EIE76863.1 - 1.6e-13 50.7 0.0 2.8e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EIE76863.1 - 6.8e-10 39.1 0.1 4.7e-07 29.9 0.0 3.1 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain SBP56 PF05694.6 EIE76863.1 - 0.04 12.4 0.0 0.058 11.8 0.0 1.2 1 0 0 1 1 1 0 56kDa selenium binding protein (SBP56) DUF3126 PF11324.3 EIE76864.1 - 0.035 13.7 0.3 0.035 13.7 0.2 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3126) Spc7 PF08317.6 EIE76865.1 - 0.0016 17.1 4.0 0.0019 16.9 2.8 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein Syntaxin_2 PF14523.1 EIE76865.1 - 0.0096 15.9 3.5 0.012 15.6 2.4 1.2 1 0 0 1 1 1 1 Syntaxin-like protein Lzipper-MIP1 PF14389.1 EIE76865.1 - 0.019 15.0 2.9 0.049 13.7 1.9 1.6 1 1 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 GAS PF13851.1 EIE76865.1 - 0.021 14.0 3.5 0.024 13.8 2.5 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding APG6 PF04111.7 EIE76865.1 - 0.031 13.3 3.3 0.035 13.1 2.3 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3450 PF11932.3 EIE76865.1 - 0.038 13.2 2.6 0.042 13.1 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF3618 PF12277.3 EIE76865.1 - 0.04 13.9 1.4 0.082 12.9 0.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3618) DUF342 PF03961.8 EIE76865.1 - 0.047 12.1 4.3 0.052 11.9 3.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Fib_alpha PF08702.5 EIE76865.1 - 0.047 13.8 2.9 0.16 12.1 2.0 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family GspL_C PF12693.2 EIE76865.1 - 0.094 12.4 1.9 0.12 12.1 1.3 1.1 1 0 0 1 1 1 0 GspL periplasmic domain CbiC PF02570.10 EIE76865.1 - 0.099 12.0 0.0 0.099 12.0 0.0 1.2 1 0 0 1 1 1 0 Precorrin-8X methylmutase Tropomyosin_1 PF12718.2 EIE76865.1 - 0.099 12.4 2.4 0.12 12.2 1.6 1.2 1 0 0 1 1 1 0 Tropomyosin like TMF_TATA_bd PF12325.3 EIE76865.1 - 0.11 12.2 3.8 0.21 11.3 1.2 1.9 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding IncA PF04156.9 EIE76865.1 - 0.13 11.8 4.6 0.16 11.5 3.2 1.2 1 0 0 1 1 1 0 IncA protein DUF4164 PF13747.1 EIE76865.1 - 0.15 12.2 2.4 0.32 11.1 1.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) Tup_N PF08581.5 EIE76865.1 - 0.16 12.2 1.6 0.18 12.0 0.8 1.5 1 1 0 1 1 1 0 Tup N-terminal DUF4208 PF13907.1 EIE76865.1 - 0.18 12.0 2.5 0.27 11.4 1.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4208) LTXXQ PF07813.7 EIE76865.1 - 0.19 12.2 2.1 0.24 11.8 1.0 1.5 1 1 0 1 1 1 0 LTXXQ motif family protein Seryl_tRNA_N PF02403.17 EIE76865.1 - 0.19 11.7 4.7 0.22 11.5 3.3 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF607 PF04678.8 EIE76865.1 - 0.19 11.6 1.3 0.2 11.5 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF607 DUF972 PF06156.8 EIE76865.1 - 0.25 11.7 3.7 0.66 10.3 2.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF972) NPV_P10 PF05531.7 EIE76865.1 - 0.25 11.6 2.0 0.72 10.1 1.4 1.7 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Nsp1_C PF05064.8 EIE76865.1 - 0.65 9.6 5.0 0.42 10.2 1.3 1.8 1 1 1 2 2 2 0 Nsp1-like C-terminal region Syntaxin PF00804.20 EIE76865.1 - 1.3 9.1 7.2 1.1 9.5 0.6 1.9 1 1 0 1 1 1 0 Syntaxin DivIC PF04977.10 EIE76865.1 - 3.1 7.3 8.3 4.6 6.8 1.4 2.2 1 1 1 2 2 2 0 Septum formation initiator Wbp11 PF09429.5 EIE76865.1 - 5.5 7.0 9.3 2.2e+02 1.8 6.5 2.4 1 1 0 1 1 1 0 WW domain binding protein 11 USP7_ICP0_bdg PF12436.3 EIE76867.1 - 7.5e-58 195.6 0.4 2.9e-56 190.4 0.0 2.5 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 UCH PF00443.24 EIE76867.1 - 2e-52 177.9 0.9 4.1e-52 176.9 0.7 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.1 EIE76867.1 - 8.1e-48 162.6 7.9 2e-45 154.8 3.5 3.5 3 0 0 3 3 3 1 Ubiquitin-specific protease C-terminal UCH_1 PF13423.1 EIE76867.1 - 4.6e-28 98.5 0.0 9e-27 94.2 0.0 2.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 EIE76867.1 - 7.2e-09 35.9 0.1 3e-08 33.9 0.0 2.1 1 0 0 1 1 1 1 MATH domain YukD PF08817.5 EIE76867.1 - 0.0045 17.5 0.2 2.1 8.9 0.0 2.7 2 0 0 2 2 2 2 WXG100 protein secretion system (Wss), protein YukD MCM PF00493.18 EIE76868.1 - 1.5e-139 464.4 0.9 1.9e-139 464.0 0.6 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EIE76868.1 - 9.3e-25 87.4 0.6 2.9e-24 85.8 0.4 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EIE76868.1 - 1e-05 24.8 0.0 0.00047 19.3 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EIE76868.1 - 4.1e-05 23.3 0.0 0.00021 21.0 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EIE76868.1 - 0.00077 19.0 0.0 0.002 17.7 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase_2 PF13335.1 EIE76868.1 - 0.031 14.6 0.4 0.1 13.0 0.3 1.8 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 EIE76868.1 - 0.07 12.6 0.0 1.3 8.4 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain Rdx PF10262.4 EIE76869.1 - 2.5e-29 101.1 0.0 3.1e-29 100.7 0.0 1.1 1 0 0 1 1 1 1 Rdx family Calsequestrin PF01216.12 EIE76869.1 - 0.081 11.6 0.0 0.094 11.4 0.0 1.0 1 0 0 1 1 1 0 Calsequestrin Ribosomal_L22 PF00237.14 EIE76870.1 - 5.8e-34 116.1 0.1 8.3e-34 115.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Phytochelatin PF05023.9 EIE76871.1 - 1.3e-57 194.2 0.0 1.6e-57 193.9 0.0 1.0 1 0 0 1 1 1 1 Phytochelatin synthase PPV_E2_C PF00511.12 EIE76872.1 - 0.09 12.7 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 E2 (early) protein, C terminal OmpH PF03938.9 EIE76873.1 - 0.0048 16.8 2.5 0.0048 16.8 1.7 2.7 2 1 0 2 2 2 1 Outer membrane protein (OmpH-like) DUF1140 PF06600.6 EIE76873.1 - 0.046 13.8 2.2 1.5 9.0 0.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1140) DUF3141 PF11339.3 EIE76873.1 - 0.24 9.6 5.3 0.24 9.6 2.4 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3141) FlaC_arch PF05377.6 EIE76873.1 - 2.3 8.1 5.6 3.7 7.4 0.1 2.9 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF1471 PF07338.8 EIE76874.1 - 0.19 11.4 2.9 1.6 8.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1471) HAD_2 PF13419.1 EIE76875.1 - 1.4e-23 83.9 0.0 1.7e-23 83.7 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EIE76875.1 - 9.8e-13 49.0 0.1 1.5e-11 45.1 0.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EIE76875.1 - 0.00013 21.5 0.0 0.00026 20.6 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.1 EIE76875.1 - 0.00023 21.0 0.0 0.063 13.1 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase HAD PF12710.2 EIE76875.1 - 0.013 15.6 0.0 0.019 15.1 0.0 1.3 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase DivIC PF04977.10 EIE76876.1 - 0.0016 17.8 0.1 0.0029 17.0 0.1 1.3 1 0 0 1 1 1 1 Septum formation initiator TMF_DNA_bd PF12329.3 EIE76876.1 - 0.016 14.9 0.3 0.026 14.3 0.2 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding SlyX PF04102.7 EIE76876.1 - 0.03 14.7 0.7 0.086 13.2 0.5 1.8 1 0 0 1 1 1 0 SlyX TMF_TATA_bd PF12325.3 EIE76876.1 - 0.047 13.4 0.1 0.086 12.5 0.1 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF1192 PF06698.6 EIE76876.1 - 0.1 12.4 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) DDE_3 PF13358.1 EIE76879.1 - 3.9e-18 65.6 0.0 7.8e-18 64.6 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE76879.1 - 4.4e-08 33.0 0.6 1.3e-07 31.5 0.5 1.9 2 0 0 2 2 2 1 Transposase RVT_1 PF00078.22 EIE76881.1 - 5.8e-09 35.6 0.0 9.3e-09 34.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) USP7_ICP0_bdg PF12436.3 EIE76882.1 - 0.09 11.9 0.0 0.09 11.9 0.0 1.0 1 0 0 1 1 1 0 ICP0-binding domain of Ubiquitin-specific protease 7 DDE_3 PF13358.1 EIE76883.1 - 4e-10 39.6 0.0 6e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_23 PF13384.1 EIE76883.1 - 0.027 14.1 0.1 0.044 13.4 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain DDE_3 PF13358.1 EIE76884.1 - 3.9e-10 39.6 1.9 3.9e-10 39.6 1.3 1.3 1 1 0 1 1 1 1 DDE superfamily endonuclease NUDIX_4 PF14815.1 EIE76884.1 - 0.031 13.6 0.4 0.037 13.4 0.2 1.2 1 0 0 1 1 1 0 NUDIX domain DDE_3 PF13358.1 EIE76885.1 - 6.9e-15 55.0 0.2 1e-14 54.5 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Asp_protease_2 PF13650.1 EIE76886.1 - 1.2e-09 38.5 0.2 3.7e-09 36.9 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.1 EIE76886.1 - 1.5e-06 27.9 0.1 4e-06 26.5 0.1 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.12 EIE76886.1 - 0.00087 19.3 0.0 0.0019 18.2 0.0 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein RVT_1 PF00078.22 EIE76886.1 - 0.0014 17.9 0.0 0.0048 16.2 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP PF00077.15 EIE76886.1 - 0.0032 17.3 0.0 0.0071 16.2 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Peptidase_A2B PF12384.3 EIE76886.1 - 0.016 14.5 0.1 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 Ty3 transposon peptidase zf-CCHC_6 PF15288.1 EIE76886.1 - 0.031 13.9 2.6 0.045 13.4 0.8 1.9 1 1 1 2 2 2 0 Zinc knuckle RVP_2 PF08284.6 EIE76886.1 - 0.039 13.8 0.0 0.081 12.8 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease Zn_protease PF05618.6 EIE76886.1 - 0.13 11.9 0.0 1.6 8.4 0.0 2.3 1 1 1 2 2 2 0 Putative ATP-dependant zinc protease RVT_1 PF00078.22 EIE76888.1 - 2.2e-12 46.8 0.1 4.2e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE76888.1 - 3.7e-12 45.7 0.8 8.6e-12 44.5 0.5 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.21 EIE76888.1 - 2e-09 37.6 0.0 7.8e-09 35.6 0.0 1.9 1 1 1 2 2 2 1 Integrase core domain RVP PF00077.15 EIE76889.1 - 9.9e-05 22.1 0.1 0.00021 21.1 0.1 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 EIE76889.1 - 0.00014 22.2 0.0 0.00039 20.8 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease peroxidase PF00141.18 EIE76890.1 - 4e-45 154.0 0.0 5.8e-45 153.5 0.0 1.2 1 0 0 1 1 1 1 Peroxidase UPF0242 PF06785.6 EIE76891.1 - 0.042 12.5 0.1 0.065 11.9 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) OCD_Mu_crystall PF02423.10 EIE76892.1 - 5.4e-59 199.5 0.2 6.4e-59 199.2 0.1 1.0 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.15 EIE76892.1 - 2.2e-09 37.5 0.0 4.4e-09 36.5 0.0 1.5 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 EIE76892.1 - 0.0055 16.9 0.2 0.063 13.5 0.0 2.3 2 0 0 2 2 2 1 Putative NAD(P)-binding GFO_IDH_MocA PF01408.17 EIE76892.1 - 0.016 15.7 0.0 0.033 14.6 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold BAH PF01426.13 EIE76893.1 - 8.6e-17 60.9 0.4 2e-16 59.7 0.3 1.6 1 0 0 1 1 1 1 BAH domain zf-HC5HC2H_2 PF13832.1 EIE76893.1 - 1.9e-15 56.8 10.9 1.9e-15 56.8 7.5 4.1 4 1 0 4 4 4 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EIE76893.1 - 9.5e-12 44.9 3.9 9.5e-12 44.9 2.7 4.6 4 1 0 4 4 4 1 PHD-like zinc-binding domain PHD PF00628.24 EIE76893.1 - 3.5e-11 42.6 61.6 1.2e-07 31.2 9.6 5.7 7 0 0 7 7 7 3 PHD-finger PHD_2 PF13831.1 EIE76893.1 - 4.6e-09 35.4 4.3 4.6e-09 35.4 3.0 5.1 5 0 0 5 5 5 2 PHD-finger GATA PF00320.22 EIE76893.1 - 4e-05 22.8 0.6 4e-05 22.8 0.4 3.6 2 0 0 2 2 2 1 GATA zinc finger ELM2 PF01448.19 EIE76893.1 - 4.4e-05 24.0 1.0 0.0004 20.9 0.4 2.8 2 1 0 2 2 2 1 ELM2 domain C1_1 PF00130.17 EIE76893.1 - 0.0032 17.1 1.9 0.0032 17.1 1.3 6.2 6 1 1 7 7 7 3 Phorbol esters/diacylglycerol binding domain (C1 domain) Ytp1 PF10355.4 EIE76894.1 - 1.1e-90 303.5 10.9 1.1e-90 303.5 7.6 2.1 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 EIE76894.1 - 9.2e-24 83.0 5.9 9.2e-24 83.0 4.1 3.5 4 0 0 4 4 4 1 Domain of unknown function (DUF2427) SR-25 PF10500.4 EIE76894.1 - 0.023 14.1 6.4 0.04 13.3 4.5 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Bap31 PF05529.7 EIE76894.1 - 0.066 12.6 0.5 0.17 11.3 0.0 1.9 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like Cytochrom_B561 PF03188.11 EIE76894.1 - 0.097 12.4 28.1 0.44 10.3 8.4 4.6 4 1 0 4 4 4 0 Eukaryotic cytochrome b561 bZIP_2 PF07716.10 EIE76895.1 - 5.6e-10 38.8 10.9 5.6e-10 38.8 7.5 2.0 2 1 1 3 3 3 2 Basic region leucine zipper bZIP_1 PF00170.16 EIE76895.1 - 3.5e-05 23.6 4.6 6.2e-05 22.8 3.2 1.4 1 0 0 1 1 1 1 bZIP transcription factor SAGA-Tad1 PF12767.2 EIE76895.1 - 0.06 12.9 1.7 0.11 12.0 1.2 1.4 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit AgrB PF04647.10 EIE76896.1 - 0.056 12.4 1.4 0.062 12.3 1.0 1.1 1 0 0 1 1 1 0 Accessory gene regulator B Orthoreo_P10 PF07204.6 EIE76896.1 - 0.22 11.3 2.8 0.16 11.6 1.3 1.3 1 1 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 RSN1_TM PF13967.1 EIE76896.1 - 0.9 9.0 4.9 0.69 9.4 2.5 1.6 1 1 0 1 1 1 0 Late exocytosis, associated with Golgi transport PBP1_TM PF14812.1 EIE76898.1 - 8.8 6.7 7.3 0.58 10.4 1.0 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PBD PF00786.23 EIE76899.1 - 8.4e-08 32.5 0.9 1.8e-07 31.4 0.3 1.9 1 1 1 2 2 2 1 P21-Rho-binding domain DUF648 PF04890.8 EIE76899.1 - 0.026 13.7 2.2 0.026 13.7 1.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF648) PTS_EIIC PF02378.13 EIE76900.1 - 0.14 10.9 0.0 0.2 10.4 0.0 1.1 1 0 0 1 1 1 0 Phosphotransferase system, EIIC MRI PF15325.1 EIE76900.1 - 0.56 11.2 4.7 0.24 12.3 1.0 2.1 2 1 1 3 3 3 0 Modulator of retrovirus infection DUF4201 PF13870.1 EIE76901.1 - 0.00055 19.4 6.9 0.0011 18.3 4.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) DUF3552 PF12072.3 EIE76901.1 - 0.0092 15.2 6.6 0.018 14.2 4.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) DUF342 PF03961.8 EIE76901.1 - 0.023 13.1 8.8 0.046 12.1 6.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Atg14 PF10186.4 EIE76901.1 - 0.15 10.9 11.1 0.13 11.1 6.6 1.5 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Imm16 PF15565.1 EIE76901.1 - 0.19 11.5 3.0 0.32 10.8 0.1 2.5 3 0 0 3 3 3 0 Immunity protein 16 SlyX PF04102.7 EIE76901.1 - 2.5 8.5 6.0 4.3 7.7 3.3 2.1 1 1 1 2 2 2 0 SlyX Med4 PF10018.4 EIE76901.1 - 2.6 7.4 9.2 2.7 7.3 3.3 2.4 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 RRM_1 PF00076.17 EIE76902.1 - 9e-28 95.7 0.0 1.7e-18 66.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE76902.1 - 5.2e-18 64.6 0.0 7.6e-10 38.4 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE76902.1 - 8.1e-16 57.7 0.0 9.6e-10 38.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EIE76902.1 - 6.7e-06 25.7 0.0 4.7e-05 23.0 0.0 2.1 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 EIE76902.1 - 0.0002 21.1 0.0 0.0047 16.7 0.0 2.1 2 0 0 2 2 2 1 RNA binding motif WD40 PF00400.27 EIE76903.1 - 1.8e-88 287.5 28.9 7.9e-11 41.4 0.1 12.6 12 1 0 12 12 12 11 WD domain, G-beta repeat Utp13 PF08625.6 EIE76903.1 - 1.2e-48 164.3 0.5 2.4e-48 163.3 0.3 1.5 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nup160 PF11715.3 EIE76903.1 - 4.3e-08 31.7 23.1 0.18 9.9 0.0 9.3 4 4 4 8 8 8 7 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EIE76903.1 - 7.9e-06 24.8 12.7 0.0025 16.6 0.5 5.6 1 1 2 4 4 4 3 Nup133 N terminal like Utp12 PF04003.7 EIE76903.1 - 0.0027 17.6 0.0 0.0075 16.1 0.0 1.8 1 0 0 1 1 1 1 Dip2/Utp12 Family Polysacc_deac_1 PF01522.16 EIE76904.1 - 5.7e-19 67.9 0.0 9.8e-19 67.1 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 EIE76904.1 - 1.4e-05 24.2 0.0 1.5e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 DUF2334 PF10096.4 EIE76904.1 - 0.099 12.0 2.1 0.2 11.0 1.5 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) Helicase_C PF00271.26 EIE76905.1 - 9.1e-12 44.6 0.0 1.9e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SUV3_C PF12513.3 EIE76905.1 - 1.9e-11 43.2 0.1 5.3e-11 41.7 0.0 1.8 2 0 0 2 2 2 1 Mitochondrial degradasome RNA helicase subunit C terminal zf-CCHC PF00098.18 EIE76906.1 - 0.0004 20.1 12.6 0.028 14.3 0.3 2.9 3 0 0 3 3 3 2 Zinc knuckle zf-CCHC_4 PF14392.1 EIE76906.1 - 0.0017 18.0 2.9 0.065 12.9 0.4 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-nanos PF05741.8 EIE76906.1 - 1.4 8.9 4.8 6.2 6.8 3.3 2.0 1 1 0 1 1 1 0 Nanos RNA binding domain RVT_1 PF00078.22 EIE76907.1 - 3.9e-34 117.9 0.0 7.1e-34 117.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HTH_38 PF13936.1 EIE76908.1 - 1.7e-06 27.4 0.0 2.5e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.1 EIE76908.1 - 9.2e-05 21.9 0.0 0.00015 21.2 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain Sigma70_r4_2 PF08281.7 EIE76908.1 - 0.00097 18.5 0.0 0.0019 17.6 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_7 PF02796.10 EIE76908.1 - 0.0014 18.4 0.1 0.003 17.3 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_28 PF13518.1 EIE76908.1 - 0.0027 17.6 0.0 0.0035 17.3 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_4 PF13613.1 EIE76908.1 - 0.0046 16.4 0.0 0.0076 15.7 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease Sigma70_r4 PF04545.11 EIE76908.1 - 0.0062 15.8 0.1 0.031 13.5 0.0 1.9 2 0 0 2 2 2 1 Sigma-70, region 4 GerE PF00196.14 EIE76908.1 - 0.0071 15.6 0.1 0.29 10.4 0.0 2.3 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family CPSase_L_D3 PF02787.14 EIE76908.1 - 0.01 15.6 0.0 0.014 15.1 0.0 1.2 1 0 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain UPF0122 PF04297.9 EIE76908.1 - 0.036 14.1 0.0 0.063 13.3 0.0 1.3 1 0 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like HTH_40 PF14493.1 EIE76908.1 - 0.094 12.9 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain DUF2839 PF10999.3 EIE76908.1 - 0.095 12.7 0.0 0.2 11.7 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2839) rve PF00665.21 EIE76909.1 - 2e-17 63.4 0.0 4.9e-17 62.1 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE76909.1 - 4.3e-17 62.1 0.1 9e-17 61.1 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 EIE76909.1 - 1.1e-07 32.1 0.0 3.1e-07 30.7 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 EIE76909.1 - 8.5e-07 28.8 0.0 4e-06 26.6 0.0 2.2 1 1 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EIE76909.1 - 0.00069 19.3 0.0 0.0016 18.1 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.5 EIE76909.1 - 0.0022 17.5 0.1 0.028 14.0 0.0 2.3 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.6 EIE76909.1 - 0.065 13.1 0.1 0.25 11.2 0.0 1.9 2 0 0 2 2 2 0 Retroviral aspartyl protease Peptidase_A2E PF12382.3 EIE76909.1 - 0.072 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Retrotransposon peptidase Peptidase_A2B PF12384.3 EIE76909.1 - 0.092 12.0 0.3 0.25 10.6 0.0 1.8 2 0 0 2 2 2 0 Ty3 transposon peptidase Peptidase_M3_N PF08439.5 EIE76909.1 - 0.13 12.3 2.3 0.12 12.4 0.2 2.0 2 0 0 2 2 2 0 Oligopeptidase F rve PF00665.21 EIE76910.1 - 1.8e-24 86.1 0.0 5.6e-24 84.5 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE76910.1 - 6.6e-17 61.5 0.0 1.3e-16 60.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE76910.1 - 7.5e-11 41.5 0.6 2.6e-10 39.8 0.4 2.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 EIE76910.1 - 0.00037 19.8 0.1 0.001 18.3 0.1 1.8 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger UBN2_2 PF14227.1 EIE76910.1 - 0.0096 15.4 0.4 0.29 10.7 0.0 2.7 3 0 0 3 3 3 1 gag-polypeptide of LTR copia-type rve_3 PF13683.1 EIE76910.1 - 0.015 14.8 0.0 0.042 13.3 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain UBN2 PF14223.1 EIE76910.1 - 0.071 12.8 0.2 0.26 11.1 0.0 2.0 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type Retrotrans_gag PF03732.12 EIE76911.1 - 9e-06 25.6 2.0 0.00024 21.0 0.0 3.3 4 0 0 4 4 4 1 Retrotransposon gag protein Atg14 PF10186.4 EIE76911.1 - 2.4 7.0 6.3 14 4.5 0.0 2.2 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Retrotrans_gag PF03732.12 EIE76912.1 - 8.1e-07 29.0 0.2 8.1e-07 29.0 0.2 3.0 4 0 0 4 4 4 1 Retrotransposon gag protein RVP PF00077.15 EIE76912.1 - 0.13 12.2 0.0 0.36 10.7 0.0 1.9 1 0 0 1 1 1 0 Retroviral aspartyl protease HTH_Tnp_Tc3_2 PF01498.13 EIE76913.1 - 5.6e-09 35.9 1.5 1.2e-08 34.8 0.7 1.8 1 1 1 2 2 2 1 Transposase DDE_3 PF13358.1 EIE76913.1 - 0.007 16.1 0.0 0.019 14.7 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_3 PF13358.1 EIE76914.1 - 4.4e-20 71.9 0.1 7.8e-20 71.1 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE76914.1 - 1.1e-17 63.8 0.5 1.1e-17 63.8 0.4 2.4 4 0 0 4 4 4 1 Transposase HTH_29 PF13551.1 EIE76914.1 - 1.2e-06 28.6 0.7 4.2e-06 26.8 0.3 2.0 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.1 EIE76914.1 - 3.5e-05 24.5 2.8 0.0013 19.5 0.1 3.6 4 1 1 5 5 5 1 Homeodomain-like domain DUF3551 PF12071.3 EIE76915.1 - 0.1 12.1 0.0 0.11 12.0 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3551) rve PF00665.21 EIE76916.1 - 2.3e-16 60.0 0.0 3.8e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain Xpo1 PF08389.7 EIE76916.1 - 0.038 13.9 1.8 0.66 9.8 0.0 2.4 2 1 0 2 2 2 0 Exportin 1-like protein DUF2763 PF10961.3 EIE76917.1 - 0.067 13.5 1.0 0.21 12.0 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2763) Glycoprotein_B PF00606.13 EIE76917.1 - 0.13 10.2 4.3 0.14 10.1 3.0 1.0 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B Folate_carrier PF01770.13 EIE76917.1 - 0.2 10.1 1.7 0.22 9.9 1.2 1.0 1 0 0 1 1 1 0 Reduced folate carrier DUF4282 PF14110.1 EIE76917.1 - 0.5 10.6 3.7 0.71 10.1 2.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4282) SseC PF04888.7 EIE76917.1 - 0.51 9.6 3.8 0.67 9.2 2.6 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Staph_haemo PF05480.6 EIE76917.1 - 0.72 9.5 5.3 4 7.1 1.4 2.3 2 0 0 2 2 2 0 Staphylococcus haemolytic protein AgrD PF05931.6 EIE76917.1 - 9.2 5.9 6.7 11 5.7 0.3 2.2 1 1 1 2 2 2 0 Staphylococcal AgrD protein DUF2763 PF10961.3 EIE76918.1 - 0.067 13.5 1.0 0.21 12.0 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2763) Glycoprotein_B PF00606.13 EIE76918.1 - 0.13 10.2 4.3 0.14 10.1 3.0 1.0 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B Folate_carrier PF01770.13 EIE76918.1 - 0.2 10.1 1.7 0.22 9.9 1.2 1.0 1 0 0 1 1 1 0 Reduced folate carrier DUF4282 PF14110.1 EIE76918.1 - 0.5 10.6 3.7 0.71 10.1 2.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4282) SseC PF04888.7 EIE76918.1 - 0.51 9.6 3.8 0.67 9.2 2.6 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Staph_haemo PF05480.6 EIE76918.1 - 0.72 9.5 5.3 4 7.1 1.4 2.3 2 0 0 2 2 2 0 Staphylococcus haemolytic protein AgrD PF05931.6 EIE76918.1 - 9.2 5.9 6.7 11 5.7 0.3 2.2 1 1 1 2 2 2 0 Staphylococcal AgrD protein DnaJ PF00226.26 EIE76919.1 - 1.4e-24 85.5 3.3 2.4e-24 84.8 2.3 1.3 1 0 0 1 1 1 1 DnaJ domain Arrestin_C PF02752.17 EIE76919.1 - 2.3e-20 73.0 0.9 1e-15 58.0 0.2 2.5 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EIE76919.1 - 1.6e-08 34.4 0.1 7.7e-08 32.2 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 EIE76919.1 - 0.03 13.8 0.0 0.072 12.5 0.0 1.6 1 1 0 1 1 1 0 Arrestin_N terminal like TTL PF03133.10 EIE76920.1 - 1.9e-58 197.7 3.7 2.6e-58 197.2 2.5 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATP-grasp_4 PF13535.1 EIE76920.1 - 8.7e-07 28.8 2.8 1.1e-05 25.2 0.4 2.5 2 1 0 2 2 2 1 ATP-grasp domain ATPgrasp_YheCD PF14398.1 EIE76920.1 - 0.00016 20.6 0.3 0.00047 19.0 0.0 1.9 2 1 0 2 2 2 1 YheC/D like ATP-grasp Dala_Dala_lig_C PF07478.8 EIE76920.1 - 0.005 16.2 0.1 1 8.7 0.0 2.9 2 1 1 3 3 3 1 D-ala D-ala ligase C-terminus Sedlin_N PF04628.8 EIE76920.1 - 0.005 16.6 4.2 0.08 12.8 0.3 3.3 3 0 0 3 3 3 1 Sedlin, N-terminal conserved region ATPgrasp_Ter PF15632.1 EIE76920.1 - 0.007 15.1 0.0 0.045 12.4 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon DNMT1-RFD PF12047.3 EIE76920.1 - 0.037 13.7 0.1 0.61 9.7 0.0 2.4 2 0 0 2 2 2 0 Cytosine specific DNA methyltransferase replication foci domain U3_assoc_6 PF08640.6 EIE76921.1 - 4.5e-26 90.4 6.0 4.5e-26 90.4 4.1 2.5 3 0 0 3 3 3 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.1 EIE76921.1 - 6.3e-07 29.4 0.1 1.1 10.0 0.0 5.4 6 1 0 6 6 6 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 EIE76921.1 - 7e-05 22.6 10.6 0.031 14.0 0.2 4.8 4 3 0 4 4 4 2 Mad3/BUB1 homology region 1 Suf PF05843.9 EIE76921.1 - 0.00018 21.3 12.3 0.021 14.5 1.6 3.7 3 1 0 3 3 3 3 Suppressor of forked protein (Suf) TPR_19 PF14559.1 EIE76921.1 - 0.00035 20.8 1.7 0.44 10.9 0.0 4.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 EIE76921.1 - 0.0015 18.3 3.3 9.8 6.3 0.0 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EIE76921.1 - 0.11 13.1 0.5 9.7 7.0 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 EIE76921.1 - 0.69 9.5 8.4 7 6.3 0.0 4.4 5 1 1 6 6 6 0 TPR repeat SR-25 PF10500.4 EIE76922.1 - 0.38 10.2 25.6 0.42 10.0 17.7 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF1777 PF08648.7 EIE76922.1 - 2.4 7.8 24.1 2.7 7.7 16.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) ICAP-1_inte_bdg PF10480.4 EIE76922.1 - 3.2 7.4 6.3 5.1 6.8 4.4 1.3 1 0 0 1 1 1 0 Beta-1 integrin binding protein FAD_binding_3 PF01494.14 EIE76923.1 - 8.4e-14 51.3 0.0 3.1e-07 29.7 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EIE76923.1 - 0.0012 18.7 0.0 0.0032 17.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EIE76923.1 - 0.0071 16.7 0.0 0.016 15.5 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIE76923.1 - 0.11 10.9 0.0 0.17 10.3 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Polysacc_deac_1 PF01522.16 EIE76924.1 - 1.6e-25 89.0 0.0 3.7e-25 87.9 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide deacetylase YycI PF09648.5 EIE76928.1 - 0.0082 15.6 0.6 0.009 15.4 0.4 1.0 1 0 0 1 1 1 1 YycH protein SF3b1 PF08920.5 EIE76928.1 - 0.02 14.9 1.0 0.051 13.5 0.1 1.9 1 1 1 2 2 2 0 Splicing factor 3B subunit 1 Pox_P21 PF05313.7 EIE76928.1 - 0.084 12.1 0.0 0.095 11.9 0.0 1.1 1 0 0 1 1 1 0 Poxvirus P21 membrane protein Flavoprotein PF02441.14 EIE76929.1 - 2.3e-30 104.9 5.1 6.1e-27 93.8 0.6 2.1 1 1 1 2 2 2 2 Flavoprotein HTH_Tnp_Tc3_2 PF01498.13 EIE76932.1 - 2.2e-09 37.2 0.2 6.3e-09 35.7 0.1 1.7 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.1 EIE76932.1 - 1.2e-05 25.4 0.0 2.8e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn helix DUF3016 PF11454.3 EIE76935.1 - 0.079 12.5 0.1 0.08 12.5 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3016) RVT_1 PF00078.22 EIE76938.1 - 6.5e-36 123.7 0.0 1.2e-35 122.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SecM PF06558.7 EIE76938.1 - 0.04 13.5 0.2 0.084 12.5 0.1 1.5 1 0 0 1 1 1 0 Secretion monitor precursor protein (SecM) Exo_endo_phos_2 PF14529.1 EIE76939.1 - 4.4e-07 29.5 0.1 1.2e-06 28.1 0.1 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EIE76939.1 - 1.3e-05 25.3 0.1 1.9e-05 24.7 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family bZIP_1 PF00170.16 EIE76940.1 - 0.0032 17.3 0.1 0.0065 16.3 0.0 1.6 1 0 0 1 1 1 1 bZIP transcription factor Herpes_UL6 PF01763.11 EIE76940.1 - 0.084 11.0 1.9 0.1 10.7 1.0 1.3 1 1 0 1 1 1 0 Herpesvirus UL6 like HALZ PF02183.13 EIE76940.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper TMF_DNA_bd PF12329.3 EIE76940.1 - 0.13 12.0 0.1 0.27 11.0 0.1 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding BLOC1_2 PF10046.4 EIE76940.1 - 0.17 12.0 1.6 0.2 11.7 0.4 1.6 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Acyltransferase PF01553.16 EIE76941.1 - 4.1e-15 55.3 0.0 6.5e-15 54.7 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase TMF_TATA_bd PF12325.3 EIE76942.1 - 0.00028 20.5 0.5 0.00031 20.4 0.3 1.2 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding CENP-F_leu_zip PF10473.4 EIE76942.1 - 0.0014 18.5 0.3 0.0016 18.3 0.2 1.1 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Golgin_A5 PF09787.4 EIE76942.1 - 0.0022 16.5 1.4 0.0023 16.5 0.9 1.0 1 0 0 1 1 1 1 Golgin subfamily A member 5 Lzipper-MIP1 PF14389.1 EIE76942.1 - 0.0039 17.2 0.5 0.005 16.9 0.4 1.2 1 0 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 Filament PF00038.16 EIE76942.1 - 0.0077 15.7 0.7 0.0096 15.4 0.5 1.0 1 0 0 1 1 1 1 Intermediate filament protein DivIC PF04977.10 EIE76942.1 - 0.0087 15.5 0.9 0.014 14.8 0.5 1.4 1 1 0 1 1 1 1 Septum formation initiator ATP-synt_B PF00430.13 EIE76942.1 - 0.011 15.5 0.2 0.013 15.2 0.2 1.1 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) FliJ PF02050.11 EIE76942.1 - 0.011 15.7 4.3 0.014 15.4 3.0 1.1 1 0 0 1 1 1 0 Flagellar FliJ protein ADIP PF11559.3 EIE76942.1 - 0.014 15.3 7.1 0.018 14.9 4.9 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding TBPIP PF07106.8 EIE76942.1 - 0.019 14.5 0.9 0.021 14.3 0.6 1.1 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Tektin PF03148.9 EIE76942.1 - 0.02 13.4 1.1 0.021 13.3 0.7 1.0 1 0 0 1 1 1 0 Tektin family ING PF12998.2 EIE76942.1 - 0.036 14.3 0.6 0.047 13.9 0.4 1.2 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding DUF3450 PF11932.3 EIE76942.1 - 0.036 13.3 4.6 0.037 13.2 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF641 PF04859.7 EIE76942.1 - 0.039 13.7 1.0 0.049 13.3 0.7 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) OmpH PF03938.9 EIE76942.1 - 0.042 13.7 5.3 0.052 13.4 3.7 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SbcD_C PF12320.3 EIE76942.1 - 0.055 13.5 0.5 0.059 13.4 0.3 1.2 1 0 0 1 1 1 0 Type 5 capsule protein repressor C-terminal domain Phage_lysis PF03245.8 EIE76942.1 - 0.055 13.4 1.3 0.066 13.2 0.9 1.2 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein Bap31 PF05529.7 EIE76942.1 - 0.074 12.5 0.8 0.088 12.2 0.6 1.1 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like COG2 PF06148.6 EIE76942.1 - 0.077 12.8 0.5 0.11 12.4 0.4 1.3 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 EST1 PF10374.4 EIE76942.1 - 0.097 12.6 0.6 0.11 12.4 0.4 1.1 1 0 0 1 1 1 0 Telomerase activating protein Est1 Mmp37 PF09139.6 EIE76942.1 - 0.11 11.4 1.3 0.12 11.3 0.9 1.0 1 0 0 1 1 1 0 Mitochondrial matrix Mmp37 DUF948 PF06103.6 EIE76942.1 - 0.18 11.6 2.2 0.22 11.4 1.2 1.4 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) IncA PF04156.9 EIE76942.1 - 0.18 11.3 3.2 0.22 11.0 2.2 1.1 1 0 0 1 1 1 0 IncA protein TrbH PF07283.6 EIE76942.1 - 0.41 10.5 3.0 0.82 9.5 0.6 1.9 1 1 1 2 2 2 0 Conjugal transfer protein TrbH Pkinase PF00069.20 EIE76943.1 - 3.5e-46 157.4 0.0 4.1e-46 157.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE76943.1 - 3.1e-26 92.0 0.0 3.6e-26 91.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE76943.1 - 0.00018 20.5 0.0 0.00023 20.2 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EIE76943.1 - 0.0019 17.3 0.0 0.0026 16.8 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family MULE PF10551.4 EIE76945.1 - 2.2e-10 40.5 0.0 3.2e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 MULE transposase domain Flexi_CP PF00286.15 EIE76945.1 - 0.067 12.9 0.0 0.092 12.4 0.0 1.3 1 0 0 1 1 1 0 Viral coat protein FAR1 PF03101.10 EIE76946.1 - 0.00055 20.3 1.8 0.00083 19.8 1.3 1.4 1 0 0 1 1 1 1 FAR1 DNA-binding domain CENP-F_leu_zip PF10473.4 EIE76947.1 - 3.3e-05 23.7 2.9 5.9e-05 22.9 2.0 1.3 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Golgin_A5 PF09787.4 EIE76947.1 - 8e-05 21.3 3.1 9.7e-05 21.0 2.1 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 5 DivIVA PF05103.8 EIE76947.1 - 8.3e-05 22.6 4.8 0.00013 22.0 3.3 1.2 1 0 0 1 1 1 1 DivIVA protein DUF3450 PF11932.3 EIE76947.1 - 0.00012 21.4 6.9 0.00017 20.9 4.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) TMF_TATA_bd PF12325.3 EIE76947.1 - 0.00026 20.6 1.9 0.00043 19.9 1.3 1.3 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding FliJ PF02050.11 EIE76947.1 - 0.003 17.6 5.8 0.003 17.6 4.0 1.6 2 0 0 2 2 2 1 Flagellar FliJ protein DUF948 PF06103.6 EIE76947.1 - 0.0057 16.4 1.4 0.012 15.4 1.0 1.5 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF948) FUSC PF04632.7 EIE76947.1 - 0.0088 14.5 0.2 0.011 14.2 0.1 1.1 1 0 0 1 1 1 1 Fusaric acid resistance protein family CCDC155 PF14662.1 EIE76947.1 - 0.012 15.1 3.5 0.023 14.3 2.4 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 DivIC PF04977.10 EIE76947.1 - 0.02 14.3 3.7 0.049 13.1 2.6 1.6 1 0 0 1 1 1 0 Septum formation initiator V_ATPase_I PF01496.14 EIE76947.1 - 0.027 12.3 1.0 0.031 12.1 0.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF904 PF06005.7 EIE76947.1 - 0.032 14.5 2.3 0.077 13.3 1.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF904) HR1 PF02185.11 EIE76947.1 - 0.043 13.5 3.9 0.1 12.3 2.7 1.6 1 0 0 1 1 1 0 Hr1 repeat CCDC144C PF14915.1 EIE76947.1 - 0.048 12.5 6.1 0.064 12.1 4.3 1.1 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region TMF_DNA_bd PF12329.3 EIE76947.1 - 0.056 13.2 2.3 0.1 12.3 1.6 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding HAUS6_N PF14661.1 EIE76947.1 - 0.062 12.6 3.2 0.083 12.2 2.2 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus AIP3 PF03915.8 EIE76947.1 - 0.066 12.1 3.5 0.075 11.9 2.4 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 APG6 PF04111.7 EIE76947.1 - 0.079 11.9 4.3 0.096 11.7 3.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 TPR_MLP1_2 PF07926.7 EIE76947.1 - 0.08 12.6 10.0 0.079 12.7 6.2 1.4 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Macoilin PF09726.4 EIE76947.1 - 0.11 10.7 7.5 0.14 10.3 5.2 1.1 1 0 0 1 1 1 0 Transmembrane protein Filament PF00038.16 EIE76947.1 - 0.16 11.3 7.2 0.16 11.3 4.4 1.3 1 1 0 1 1 1 0 Intermediate filament protein AATF-Che1 PF13339.1 EIE76947.1 - 0.17 12.0 4.3 0.35 11.0 3.0 1.7 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor TBPIP PF07106.8 EIE76947.1 - 0.21 11.1 5.8 0.21 11.1 3.6 1.4 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) GrpE PF01025.14 EIE76947.1 - 0.27 10.7 2.9 0.55 9.7 2.0 1.5 1 0 0 1 1 1 0 GrpE Spc24 PF08286.6 EIE76947.1 - 0.28 10.9 5.3 0.37 10.5 3.4 1.5 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 Striatin PF08232.7 EIE76947.1 - 0.44 10.8 5.5 0.81 10.0 3.7 1.6 1 1 0 1 1 1 0 Striatin family DUF4515 PF14988.1 EIE76947.1 - 0.82 9.2 10.6 1.8 8.1 7.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4515) HALZ PF02183.13 EIE76947.1 - 1.1 9.0 5.1 0.21 11.3 0.6 2.1 2 1 1 3 3 2 0 Homeobox associated leucine zipper DUF4140 PF13600.1 EIE76947.1 - 1.4 9.3 7.5 0.51 10.8 1.3 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF972 PF06156.8 EIE76947.1 - 1.7 9.0 4.9 2.3 8.5 3.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF972) IncA PF04156.9 EIE76947.1 - 3.7 7.0 11.6 2.8 7.5 6.4 1.5 1 1 0 1 1 1 0 IncA protein ADIP PF11559.3 EIE76947.1 - 6.3 6.6 14.1 2 8.2 7.2 1.8 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF4407 PF14362.1 EIE76947.1 - 7.3 5.4 11.2 0.33 9.8 4.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DDE_3 PF13358.1 EIE76948.1 - 3.5e-19 69.0 0.0 7.8e-19 67.8 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE76948.1 - 3.5e-16 59.0 1.2 2e-15 56.5 0.2 2.6 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 EIE76948.1 - 9.7e-06 25.7 0.2 2.8e-05 24.2 0.2 1.8 1 0 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.1 EIE76948.1 - 0.00022 21.9 2.6 0.0087 16.8 0.1 3.6 3 1 1 4 4 3 1 Homeodomain-like domain HTH_23 PF13384.1 EIE76948.1 - 0.00027 20.4 0.1 0.0091 15.6 0.0 2.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_38 PF13936.1 EIE76948.1 - 0.00033 20.1 0.1 0.00099 18.6 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_21 PF13276.1 EIE76948.1 - 0.00047 20.1 0.1 0.13 12.2 0.0 2.9 3 0 0 3 3 3 1 HTH-like domain rve PF00665.21 EIE76948.1 - 0.00055 20.0 0.0 0.0016 18.5 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Sigma70_r4_2 PF08281.7 EIE76948.1 - 0.002 17.5 1.2 0.13 11.6 0.0 3.3 4 0 0 4 4 4 1 Sigma-70, region 4 HTH_28 PF13518.1 EIE76948.1 - 0.0023 17.8 0.1 0.01 15.8 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_4 PF13613.1 EIE76948.1 - 0.084 12.4 0.1 0.2 11.1 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_7 PF02796.10 EIE76948.1 - 0.092 12.6 1.1 4.3 7.2 0.0 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain of resolvase CPSase_L_D3 PF02787.14 EIE76948.1 - 0.14 11.8 0.1 0.36 10.6 0.0 1.7 2 0 0 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain LacI PF00356.16 EIE76948.1 - 0.4 10.3 1.8 2.8 7.6 0.2 2.5 3 0 0 3 3 3 0 Bacterial regulatory proteins, lacI family HTH_Tnp_ISL3 PF13542.1 EIE76948.1 - 0.59 9.3 3.5 15 4.8 0.1 3.0 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 RVT_1 PF00078.22 EIE76949.1 - 1.1e-18 67.3 0.0 1.4e-14 53.9 0.0 2.6 2 1 1 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) RNA_pol_Rpb4 PF03874.11 EIE76950.1 - 0.053 13.5 0.5 0.077 13.0 0.4 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb4 Acyltransferase PF01553.16 EIE76951.1 - 2e-36 124.3 0.1 3e-36 123.7 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Lip_A_acyltrans PF03279.8 EIE76951.1 - 0.0016 17.3 0.1 0.0026 16.7 0.1 1.3 1 1 0 1 1 1 1 Bacterial lipid A biosynthesis acyltransferase Cyclin_N PF00134.18 EIE76953.1 - 1.7e-13 50.2 0.6 1.7e-13 50.2 0.4 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Ku_PK_bind PF08785.6 EIE76953.1 - 0.033 14.1 0.4 0.078 12.8 0.3 1.7 1 1 0 1 1 1 0 Ku C terminal domain like DUF1878 PF08963.5 EIE76953.1 - 0.046 13.9 1.5 0.16 12.1 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1878) TFIIB PF00382.14 EIE76953.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Transcription factor TFIIB repeat Mg_trans_NIPA PF05653.9 EIE76954.1 - 0.16 10.9 1.9 0.22 10.4 1.3 1.1 1 0 0 1 1 1 0 Magnesium transporter NIPA DUF3185 PF11381.3 EIE76954.1 - 0.38 10.5 3.3 0.22 11.3 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) DUF3592 PF12158.3 EIE76954.1 - 0.54 10.0 3.8 0.87 9.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3592) Sigma70_r1_2 PF00140.15 EIE76954.1 - 7.9 6.2 6.2 7.7 6.2 0.0 3.1 2 1 1 3 3 3 0 Sigma-70 factor, region 1.2 RhoGAP PF00620.22 EIE76955.1 - 1.2e-40 138.6 0.1 3.6e-40 137.0 0.0 1.9 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.24 EIE76955.1 - 4.6e-12 46.0 0.2 1.7e-11 44.2 0.0 2.1 2 0 0 2 2 2 1 PH domain PX PF00787.19 EIE76955.1 - 6.4e-12 45.2 0.0 2e-11 43.6 0.0 1.9 1 0 0 1 1 1 1 PX domain PH_11 PF15413.1 EIE76955.1 - 1.2e-07 31.9 2.0 2.1e-07 31.1 0.0 2.4 2 1 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.1 EIE76955.1 - 0.00037 20.5 0.1 0.002 18.1 0.0 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain TMF_DNA_bd PF12329.3 EIE76955.1 - 0.0073 16.0 3.0 0.038 13.7 2.1 2.3 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding IncA PF04156.9 EIE76955.1 - 0.38 10.3 4.9 0.25 10.9 1.4 2.0 2 0 0 2 2 2 0 IncA protein ENTH PF01417.15 EIE76956.1 - 4.1e-46 155.9 1.4 7.9e-46 154.9 1.0 1.5 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 EIE76956.1 - 3.7e-06 25.8 0.3 5.3e-06 25.3 0.2 1.2 1 0 0 1 1 1 1 ANTH domain VHS PF00790.14 EIE76956.1 - 0.017 14.7 0.2 0.051 13.2 0.2 1.7 1 1 0 1 1 1 0 VHS domain GRP PF07172.6 EIE76956.1 - 0.13 12.7 21.5 0.14 12.6 13.8 1.9 2 0 0 2 2 2 0 Glycine rich protein family PH PF00169.24 EIE76957.1 - 1.1e-19 70.5 1.3 1.1e-19 70.5 0.9 2.7 3 0 0 3 3 3 1 PH domain SAM_2 PF07647.12 EIE76957.1 - 1.6e-15 56.7 0.1 3.2e-15 55.7 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.1 EIE76957.1 - 5.2e-14 51.5 0.0 1.4e-13 50.2 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SAM_1 PF00536.25 EIE76957.1 - 1.9e-13 50.3 0.2 4.1e-13 49.2 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_1 PF00018.23 EIE76957.1 - 3.6e-12 45.4 0.2 1e-11 43.9 0.2 1.9 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EIE76957.1 - 7.2e-10 38.2 0.1 1.6e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain CH PF00307.26 EIE76957.1 - 1.2e-07 31.7 0.0 4.3e-07 29.9 0.0 2.0 2 0 0 2 2 2 1 Calponin homology (CH) domain PH_11 PF15413.1 EIE76957.1 - 1.5e-07 31.6 5.8 7.9e-06 26.0 2.6 3.6 2 1 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.1 EIE76957.1 - 0.001 19.0 0.9 0.0037 17.3 0.6 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.1 EIE76957.1 - 0.013 15.3 0.5 0.03 14.2 0.4 1.6 1 0 0 1 1 1 0 PH domain Pkinase PF00069.20 EIE76958.1 - 4.6e-70 235.7 0.0 1.2e-69 234.3 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE76958.1 - 9.8e-41 139.5 0.0 2.9e-40 137.9 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE76958.1 - 3e-08 32.9 0.0 1.2e-07 31.0 0.0 1.9 2 0 0 2 2 2 1 Kinase-like DUF2779 PF11074.3 EIE76958.1 - 0.0036 17.3 1.6 0.64 10.0 0.4 2.7 2 0 0 2 2 2 2 Domain of unknown function(DUF2779) APH PF01636.18 EIE76958.1 - 0.064 12.9 0.1 0.27 10.9 0.0 2.0 1 1 0 1 1 1 0 Phosphotransferase enzyme family MT-A70 PF05063.9 EIE76960.1 - 2.7e-34 118.2 0.1 5.2e-32 110.8 0.1 2.2 1 1 0 1 1 1 1 MT-A70 FlxA PF14282.1 EIE76960.1 - 0.0061 16.4 1.0 0.0099 15.8 0.7 1.3 1 0 0 1 1 1 1 FlxA-like protein UPF0020 PF01170.13 EIE76960.1 - 0.055 13.0 0.1 0.13 11.8 0.0 1.7 3 0 0 3 3 3 0 Putative RNA methylase family UPF0020 Nnf1 PF03980.9 EIE76961.1 - 4.8e-10 39.4 12.8 4.8e-10 39.4 8.9 1.7 2 0 0 2 2 2 1 Nnf1 Chibby PF14645.1 EIE76961.1 - 0.018 14.9 0.3 0.018 14.9 0.2 1.9 2 0 0 2 2 2 0 Chibby family PI31_Prot_N PF11566.3 EIE76961.1 - 0.034 13.7 3.7 0.041 13.4 2.1 1.8 1 1 0 1 1 1 0 PI31 proteasome regulator N-terminal Amidase PF01425.16 EIE76961.1 - 0.066 12.0 0.6 0.08 11.7 0.4 1.1 1 0 0 1 1 1 0 Amidase DUF4407 PF14362.1 EIE76961.1 - 0.11 11.3 2.0 0.13 11.2 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HALZ PF02183.13 EIE76961.1 - 0.34 10.6 7.3 0.14 11.8 1.4 2.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper Syntaxin-6_N PF09177.6 EIE76961.1 - 0.52 10.7 6.4 0.91 9.9 0.7 2.7 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Rab5-bind PF09311.6 EIE76961.1 - 0.83 9.5 13.3 0.24 11.2 1.9 2.4 2 1 0 2 2 2 0 Rabaptin-like protein Cep57_CLD_2 PF14197.1 EIE76961.1 - 1.3 9.0 11.4 4.6 7.2 2.0 2.5 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 DUF573 PF04504.9 EIE76961.1 - 2.4 8.4 6.7 0.92 9.8 1.0 2.5 2 1 0 2 2 2 0 Protein of unknown function, DUF573 DUF948 PF06103.6 EIE76961.1 - 3.5 7.5 6.6 5.5 6.9 0.4 2.8 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) PspB PF06667.7 EIE76961.1 - 7.4 6.5 7.4 5.6 6.9 1.3 2.5 2 0 0 2 2 2 0 Phage shock protein B TOM13 PF08219.6 EIE76962.1 - 1.4e-19 69.5 0.2 2e-19 69.1 0.2 1.3 1 0 0 1 1 1 1 Outer membrane protein TOM13 p450 PF00067.17 EIE76963.1 - 6.2e-28 97.5 0.0 7.3e-28 97.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sugar_tr PF00083.19 EIE76964.1 - 2.2e-54 184.7 23.8 2.6e-54 184.5 16.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIE76964.1 - 1.5e-26 92.9 23.9 2e-20 72.8 7.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Spc97_Spc98 PF04130.8 EIE76966.1 - 1.2e-126 423.1 20.3 1.2e-126 423.1 14.0 1.9 2 0 0 2 2 2 1 Spc97 / Spc98 family Mod_r PF07200.8 EIE76966.1 - 2.7 7.9 9.1 0.1 12.4 0.4 2.8 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein PAT1 PF09770.4 EIE76967.1 - 5.1 5.2 23.8 6.1 4.9 16.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 6PGD PF00393.14 EIE76968.1 - 3.5e-138 459.7 0.0 4.2e-138 459.4 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EIE76968.1 - 2.4e-53 180.3 0.0 3.5e-53 179.7 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EIE76968.1 - 0.00051 20.0 0.1 0.02 14.9 0.0 2.8 3 0 0 3 3 3 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 EIE76968.1 - 0.021 15.2 0.0 0.04 14.3 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF4042 PF13251.1 EIE76969.1 - 2.9e-14 52.9 0.9 2.4e-12 46.7 0.0 3.2 3 1 0 3 3 3 1 Domain of unknown function (DUF4042) HEAT PF02985.17 EIE76969.1 - 1.1e-05 25.1 3.8 0.26 11.4 0.0 4.4 4 0 0 4 4 4 3 HEAT repeat HEAT_EZ PF13513.1 EIE76969.1 - 0.0024 18.2 0.1 1.2 9.7 0.0 4.0 4 1 0 4 4 4 1 HEAT-like repeat HEAT_2 PF13646.1 EIE76970.1 - 1.5e-13 50.7 0.0 5.4e-06 26.6 0.1 3.3 2 1 0 2 2 2 2 HEAT repeats HEAT_EZ PF13513.1 EIE76970.1 - 4.9e-12 45.9 2.1 1.7e-05 25.1 0.1 4.3 4 1 1 5 5 5 3 HEAT-like repeat HEAT PF02985.17 EIE76970.1 - 7.1e-11 41.2 5.7 0.00036 20.3 0.1 4.7 4 0 0 4 4 4 3 HEAT repeat Arm PF00514.18 EIE76970.1 - 0.0014 18.3 9.7 6.8 6.6 0.1 5.3 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat Condensin2nSMC PF12422.3 EIE76970.1 - 0.011 15.4 0.7 6.3 6.5 0.0 3.3 3 0 0 3 3 3 0 Condensin II non structural maintenance of chromosomes subunit ABC_membrane_2 PF06472.10 EIE76971.1 - 2.2e-61 207.4 0.1 3e-61 207.0 0.1 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EIE76971.1 - 1.3e-15 57.9 0.0 7.9e-15 55.3 0.0 2.2 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 EIE76971.1 - 6.2e-05 23.0 0.1 0.00018 21.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 EIE76971.1 - 0.0053 16.0 0.1 0.078 12.1 0.0 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EIE76971.1 - 0.024 14.1 0.0 0.053 13.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 EIE76971.1 - 0.15 11.2 0.0 0.3 10.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_23 PF13476.1 EIE76971.1 - 0.46 10.7 13.6 4.4 7.5 7.0 2.7 2 1 0 2 2 2 0 AAA domain Protoglobin PF11563.3 EIE76972.1 - 0.057 13.0 0.3 0.2 11.3 0.0 2.0 2 1 1 3 3 3 0 Protoglobin PRESAN PF09687.5 EIE76972.1 - 0.21 11.6 5.5 0.26 11.3 0.9 2.7 2 1 1 3 3 3 0 Plasmodium RESA N-terminal Aminotran_3 PF00202.16 EIE76973.1 - 4.5e-12 45.4 0.0 6.7e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-III zf-H2C2_2 PF13465.1 EIE76974.1 - 1.6e-25 88.0 17.3 2.2e-07 30.8 0.0 4.7 4 0 0 4 4 4 4 Zinc-finger double domain zf-C2H2 PF00096.21 EIE76974.1 - 3.3e-18 64.8 28.2 9.8e-06 25.6 0.8 5.1 5 1 1 6 6 6 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIE76974.1 - 2.6e-10 39.8 25.0 0.00081 19.5 1.0 4.9 5 0 0 5 5 5 4 C2H2-type zinc finger zf-TRAF PF02176.13 EIE76974.1 - 0.054 13.8 0.9 0.054 13.8 0.6 2.9 1 1 1 3 3 3 0 TRAF-type zinc finger RPAP2_Rtr1 PF04181.8 EIE76974.1 - 0.64 10.1 10.0 7.5e+02 0.3 6.9 3.1 1 1 0 1 1 1 0 Rtr1/RPAP2 family zf-C2H2_jaz PF12171.3 EIE76974.1 - 0.68 10.1 9.7 8.8 6.6 0.0 4.2 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding UAA PF08449.6 EIE76975.1 - 8.8e-38 129.9 5.4 1e-37 129.6 3.7 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 EIE76975.1 - 4.1e-11 43.0 2.6 5.3e-11 42.6 1.8 1.0 1 0 0 1 1 1 1 EamA-like transporter family TPT PF03151.11 EIE76975.1 - 9e-07 28.6 4.5 1.1e-06 28.3 3.1 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EmrE PF13536.1 EIE76975.1 - 0.0012 18.9 4.3 0.0016 18.6 3.0 1.1 1 0 0 1 1 1 1 Multidrug resistance efflux transporter 7TM_GPCR_Str PF10326.4 EIE76975.1 - 0.0028 16.8 2.6 0.0035 16.5 1.8 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Str PP2C PF00481.16 EIE76977.1 - 5.2e-14 52.2 0.0 1.6e-12 47.3 0.0 3.2 1 1 1 2 2 2 1 Protein phosphatase 2C PP2C_2 PF13672.1 EIE76977.1 - 1.4e-07 31.0 0.0 2.3e-06 27.1 0.0 2.5 3 0 0 3 3 3 1 Protein phosphatase 2C Phage_int_SAM_1 PF02899.12 EIE76978.1 - 0.021 14.9 0.1 4.2 7.6 0.0 2.5 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain DPBB_1 PF03330.13 EIE76981.1 - 1.4e-07 31.4 0.2 2.6e-07 30.5 0.1 1.6 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EIE76981.1 - 0.0057 16.3 0.1 0.008 15.8 0.1 1.3 1 0 0 1 1 1 1 Barwin family Gal_Lectin PF02140.13 EIE76981.1 - 0.02 15.2 0.2 0.028 14.7 0.1 1.2 1 0 0 1 1 1 0 Galactose binding lectin domain MFS_1 PF07690.11 EIE76982.1 - 2.2e-32 112.1 24.0 2.4e-32 112.0 16.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Phage_holin_5 PF06946.6 EIE76982.1 - 0.011 15.9 0.6 0.011 15.9 0.4 2.8 3 1 0 3 3 3 0 Phage holin Urease_gamma PF00547.13 EIE76982.1 - 0.14 12.1 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Urease, gamma subunit Pribosyl_synth PF14572.1 EIE76983.1 - 3.3e-47 160.6 3.6 8.8e-38 129.8 1.7 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 EIE76983.1 - 3.8e-46 155.5 1.2 3.8e-45 152.3 0.1 2.3 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 EIE76983.1 - 1.2e-11 44.4 1.2 1.2e-10 41.1 0.5 2.2 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EIE76983.1 - 0.031 13.4 0.4 0.056 12.6 0.2 1.4 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase VID27 PF08553.5 EIE76984.1 - 1.9e-98 330.6 16.1 1.2e-93 314.8 11.2 4.2 1 1 0 1 1 1 1 VID27 cytoplasmic protein Glyco_transf_15 PF01793.11 EIE76985.1 - 2.8e-81 273.0 14.7 3.6e-81 272.7 10.2 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Glyco_transf_15 PF01793.11 EIE76986.1 - 2.5e-96 322.5 4.1 3.3e-96 322.1 2.8 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF456 PF04306.8 EIE76987.1 - 0.054 13.5 1.3 0.1 12.6 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF456) YoqO PF14037.1 EIE76988.1 - 0.044 13.9 1.1 0.043 13.9 0.8 1.1 1 0 0 1 1 1 0 YoqO-like protein PUF PF00806.14 EIE76989.1 - 2e-61 200.1 12.0 1.1e-08 34.0 0.0 7.5 7 0 0 7 7 7 7 Pumilio-family RNA binding repeat Phi-29_GP3 PF05435.6 EIE76990.1 - 0.02 14.1 0.1 0.026 13.7 0.1 1.1 1 0 0 1 1 1 0 Phi-29 DNA terminal protein GP3 GATA PF00320.22 EIE76991.1 - 1.1e-30 104.6 17.3 4.2e-16 58.0 3.2 2.6 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 EIE76991.1 - 0.0013 17.9 3.7 0.21 10.9 0.1 2.3 2 0 0 2 2 2 2 TFIIB zinc-binding Cytochrom_c3_2 PF14537.1 EIE76991.1 - 0.015 15.6 7.1 0.11 12.8 0.7 2.5 2 0 0 2 2 2 0 Cytochrome c3 Cytochrome_C7 PF14522.1 EIE76991.1 - 0.049 13.2 5.2 0.054 13.1 0.3 2.6 2 0 0 2 2 2 0 Cytochrome c7 COX5B PF01215.14 EIE76991.1 - 0.11 12.2 0.4 0.96 9.1 0.1 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase subunit Vb eIF-5_eIF-2B PF01873.12 EIE76991.1 - 0.24 11.0 4.3 2.3 7.9 0.2 2.4 2 0 0 2 2 2 0 Domain found in IF2B/IF5 HypA PF01155.14 EIE76991.1 - 0.25 11.0 3.0 2.7 7.6 0.4 2.3 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family OrfB_Zn_ribbon PF07282.6 EIE76991.1 - 0.77 9.4 8.9 0.68 9.6 0.5 2.9 2 1 0 3 3 3 0 Putative transposase DNA-binding domain bZIP_1 PF00170.16 EIE76992.1 - 5.9e-07 29.3 20.0 3.1e-06 27.0 13.4 2.6 1 1 1 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.10 EIE76992.1 - 5.5e-06 26.1 18.6 9.3e-06 25.3 10.3 3.0 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_Maf PF03131.12 EIE76992.1 - 0.0013 18.9 12.7 0.0013 18.9 8.8 2.7 2 1 1 3 3 3 1 bZIP Maf transcription factor SieB PF14163.1 EIE76992.1 - 0.0049 16.4 0.2 0.026 14.0 0.1 2.3 2 0 0 2 2 2 1 Superinfection exclusion protein B DUF607 PF04678.8 EIE76992.1 - 0.12 12.2 7.5 0.17 11.7 2.3 2.9 3 0 0 3 3 3 0 Protein of unknown function, DUF607 TSC22 PF01166.13 EIE76992.1 - 3.3 7.7 14.4 0.1 12.5 4.7 2.4 2 0 0 2 2 2 0 TSC-22/dip/bun family CutA1 PF03091.10 EIE76993.1 - 0.044 13.4 0.0 0.055 13.1 0.0 1.1 1 0 0 1 1 1 0 CutA1 divalent ion tolerance protein DDE_3 PF13358.1 EIE76994.1 - 4.6e-05 23.1 0.0 4.8e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EIE76995.1 - 2.5e-09 37.0 0.1 2.6e-09 36.9 0.1 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE76996.1 - 1.3e-09 37.9 0.9 2.4e-09 37.0 0.6 1.4 1 0 0 1 1 1 1 Transposase SR-25 PF10500.4 EIE76997.1 - 0.093 12.1 9.7 0.12 11.8 6.7 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF1645 PF07816.6 EIE76997.1 - 0.43 11.0 5.3 0.5 10.7 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) Dehydrin PF00257.14 EIE76997.1 - 0.47 10.7 3.2 0.61 10.4 2.2 1.1 1 0 0 1 1 1 0 Dehydrin DDE_3 PF13358.1 EIE76998.1 - 9.3e-06 25.4 0.0 9.3e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease B56 PF01603.15 EIE76999.1 - 0.059 11.9 0.0 0.075 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) dCMP_cyt_deam_1 PF00383.17 EIE77000.1 - 2.2e-16 59.3 0.0 2.6e-16 59.1 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 EIE77000.1 - 1.8e-10 40.8 0.0 2.8e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.1 EIE77000.1 - 0.023 14.1 0.4 1.3 8.4 0.1 2.1 1 1 1 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases SHS2_Rpb7-N PF03876.12 EIE77001.1 - 8.5e-10 38.6 0.0 1.9e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 DUF3593 PF12159.3 EIE77002.1 - 0.042 13.6 0.5 0.079 12.7 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3593) DAGAT PF03982.8 EIE77003.1 - 2.8e-101 338.1 0.0 3.5e-101 337.7 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase DDE_3 PF13358.1 EIE77005.1 - 7.5e-08 32.2 0.0 1.1e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EIE77006.1 - 1.4e-11 44.3 0.1 1.9e-11 43.9 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1033 PF06279.6 EIE77006.1 - 0.011 15.5 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1033) Myb_DNA-bind_5 PF13873.1 EIE77006.1 - 0.028 14.2 0.4 3.6 7.5 0.2 2.4 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain HMG_box PF00505.14 EIE77006.1 - 0.14 12.4 0.7 0.24 11.6 0.5 1.5 1 1 0 1 1 1 0 HMG (high mobility group) box NFRKB_winged PF14465.1 EIE77006.1 - 0.23 11.3 1.8 1.2 9.0 0.5 2.0 1 1 1 2 2 2 0 NFRKB Winged Helix-like rve PF00665.21 EIE77009.1 - 4.1e-27 94.6 0.0 6.8e-27 93.9 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 EIE77009.1 - 2.3e-05 23.8 0.0 5.3e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE77010.1 - 7.5e-10 38.5 0.0 1.6e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease PF09668.5 EIE77010.1 - 0.026 14.0 0.0 0.043 13.3 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease AMIN PF11741.3 EIE77010.1 - 0.093 12.6 2.2 5 7.1 0.0 3.5 3 1 1 4 4 4 0 AMIN domain Phage_HK97_TLTM PF06120.6 EIE77010.1 - 0.34 10.1 3.4 0.55 9.5 2.3 1.2 1 0 0 1 1 1 0 Tail length tape measure protein DUF1759 PF03564.10 EIE77011.1 - 0.0023 17.7 0.3 0.0023 17.7 0.2 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1759) Transposase_21 PF02992.9 EIE77012.1 - 2.7e-21 75.6 0.0 4.6e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DUF1258 PF06869.7 EIE77012.1 - 0.0044 16.1 0.0 0.0073 15.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) FKBP_N PF01346.13 EIE77013.1 - 0.0058 16.6 1.5 0.0058 16.6 1.0 2.2 2 0 0 2 2 2 1 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase LAG1-DNAbind PF09271.6 EIE77013.1 - 0.052 14.0 1.4 0.074 13.5 0.2 1.8 2 0 0 2 2 2 0 LAG1, DNA binding YebO PF13974.1 EIE77013.1 - 0.28 10.9 6.9 7.5 6.4 0.0 2.4 2 0 0 2 2 2 0 YebO-like protein HTH_37 PF13744.1 EIE77013.1 - 2 8.2 7.2 22 4.9 3.7 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain rve PF00665.21 EIE77014.1 - 1.9e-22 79.6 0.0 4.7e-22 78.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE77014.1 - 1.5e-15 57.1 0.1 2.9e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.12 EIE77014.1 - 8.2e-09 35.4 0.1 2.4e-08 33.9 0.1 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein Chromo PF00385.19 EIE77014.1 - 4.4e-08 32.6 0.1 1e-07 31.5 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.1 EIE77014.1 - 5.3e-05 23.6 0.0 0.00012 22.4 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.5 EIE77014.1 - 0.00044 19.5 1.6 0.0015 17.8 1.1 2.0 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Asp_protease PF09668.5 EIE77014.1 - 0.0082 15.7 0.0 0.019 14.5 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EIE77014.1 - 0.023 14.4 0.0 0.058 13.2 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease UBN2 PF14223.1 EIE77014.1 - 0.14 11.9 0.0 0.37 10.5 0.0 1.8 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type DUF972 PF06156.8 EIE77015.1 - 3.7e-05 24.0 1.8 6.5e-05 23.2 1.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF972) TSC22 PF01166.13 EIE77015.1 - 7.1e-05 22.6 1.1 0.00016 21.5 0.7 1.5 1 0 0 1 1 1 1 TSC-22/dip/bun family DUF904 PF06005.7 EIE77015.1 - 0.01 16.1 1.9 0.018 15.3 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DUF947 PF06102.7 EIE77015.1 - 0.054 13.3 0.1 0.094 12.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF947) Syntaxin PF00804.20 EIE77015.1 - 0.067 13.3 0.4 0.13 12.4 0.3 1.5 1 0 0 1 1 1 0 Syntaxin DivIC PF04977.10 EIE77015.1 - 0.17 11.3 1.0 0.33 10.4 0.7 1.4 1 0 0 1 1 1 0 Septum formation initiator DUF4200 PF13863.1 EIE77015.1 - 0.56 10.1 4.7 1 9.3 3.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) RVT_1 PF00078.22 EIE77016.1 - 1.6e-25 89.7 0.0 2.8e-25 88.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EIE77016.1 - 1.4e-13 50.5 0.0 3.4e-13 49.2 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase DDE_Tnp_IS1595 PF12762.2 EIE77018.1 - 7.9e-15 54.9 0.0 6.3e-09 35.8 0.0 2.7 1 1 1 2 2 2 2 ISXO2-like transposase domain DUF1203 PF06718.6 EIE77019.1 - 0.034 13.9 0.0 0.053 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1203) DUF3983 PF13137.1 EIE77019.1 - 0.12 12.0 0.3 3.8 7.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3983) Pec_lyase_N PF04431.8 EIE77019.1 - 0.42 10.7 2.8 10 6.2 0.1 3.0 3 0 0 3 3 3 0 Pectate lyase, N terminus Transposase_21 PF02992.9 EIE77020.1 - 3e-22 78.8 0.0 4.6e-22 78.2 0.0 1.2 1 0 0 1 1 1 1 Transposase family tnp2 DUF1258 PF06869.7 EIE77020.1 - 0.0021 17.1 0.0 0.0034 16.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) DDE_3 PF13358.1 EIE77021.1 - 4.3e-21 75.2 0.4 5.9e-21 74.7 0.3 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Med15 PF09606.5 EIE77022.1 - 0.037 12.2 15.1 0.053 11.7 10.5 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal FlgM PF04316.8 EIE77022.1 - 3.4 7.6 5.8 20 5.2 3.5 2.2 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM Transposase_21 PF02992.9 EIE77024.1 - 3.3e-08 32.8 0.0 5.6e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DDE_3 PF13358.1 EIE77026.1 - 2.8e-20 72.5 0.1 5.3e-20 71.6 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE77026.1 - 6.4e-16 58.1 1.7 2.2e-15 56.4 0.3 2.4 3 0 0 3 3 2 1 Transposase HTH_29 PF13551.1 EIE77026.1 - 2.4e-06 27.6 0.3 7.8e-06 26.0 0.2 1.9 2 0 0 2 2 1 1 Winged helix-turn helix HTH_38 PF13936.1 EIE77026.1 - 1.1e-05 24.8 0.0 2.6e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_32 PF13565.1 EIE77026.1 - 7.6e-05 23.4 2.4 0.033 14.9 0.1 3.7 4 0 0 4 4 3 1 Homeodomain-like domain HTH_23 PF13384.1 EIE77026.1 - 7.9e-05 22.1 0.0 0.0022 17.5 0.0 2.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.1 EIE77026.1 - 0.00081 19.3 0.0 0.0044 16.9 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.7 EIE77026.1 - 0.00089 18.6 0.5 0.019 14.3 0.0 2.6 3 0 0 3 3 3 1 Sigma-70, region 4 HTH_7 PF02796.10 EIE77026.1 - 0.0012 18.6 1.0 0.084 12.7 0.0 2.9 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase HTH_21 PF13276.1 EIE77026.1 - 0.0027 17.6 0.7 0.16 11.9 0.0 2.7 3 0 0 3 3 2 1 HTH-like domain rve PF00665.21 EIE77026.1 - 0.0044 17.1 0.0 0.014 15.5 0.0 2.0 2 1 0 2 2 2 1 Integrase core domain HTH_Tnp_4 PF13613.1 EIE77026.1 - 0.017 14.6 0.1 0.046 13.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_36 PF13730.1 EIE77026.1 - 0.037 14.1 0.3 3.3 7.9 0.0 3.0 3 0 0 3 3 2 0 Helix-turn-helix domain CPSase_L_D3 PF02787.14 EIE77026.1 - 0.046 13.4 0.0 0.11 12.2 0.0 1.7 2 0 0 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain LacI PF00356.16 EIE77026.1 - 0.065 12.8 0.9 12 5.6 0.0 2.7 3 0 0 3 3 3 0 Bacterial regulatory proteins, lacI family HTH_Tnp_ISL3 PF13542.1 EIE77026.1 - 0.095 11.9 2.3 6.9 5.9 0.0 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 UPF0122 PF04297.9 EIE77026.1 - 0.12 12.4 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like HTH_33 PF13592.1 EIE77026.1 - 0.12 11.9 1.4 1.2 8.7 0.0 3.0 4 0 0 4 4 4 0 Winged helix-turn helix Sigma70_r4 PF04545.11 EIE77026.1 - 0.15 11.3 0.5 0.63 9.3 0.0 2.2 3 0 0 3 3 3 0 Sigma-70, region 4 HTH_17 PF12728.2 EIE77026.1 - 0.62 10.3 3.0 12 6.2 0.1 2.7 3 0 0 3 3 2 0 Helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.13 EIE77028.1 - 4.3e-06 26.6 0.1 5.2e-06 26.4 0.1 1.2 1 0 0 1 1 1 1 Transposase rve PF00665.21 EIE77029.1 - 7.8e-23 80.8 0.0 2e-22 79.5 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE77029.1 - 8.6e-16 57.9 0.3 2e-15 56.7 0.2 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE77029.1 - 3.8e-11 42.4 1.1 9.2e-11 41.2 0.7 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.12 EIE77029.1 - 0.00049 20.1 0.9 0.0022 17.9 0.6 2.2 1 0 0 1 1 1 1 Retrotransposon gag protein zf-H2C2 PF09337.5 EIE77029.1 - 0.0014 17.9 0.1 0.0039 16.5 0.1 1.9 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger UBN2_2 PF14227.1 EIE77029.1 - 0.0044 16.5 1.0 0.047 13.2 0.0 2.6 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type DUF2246 PF10229.4 EIE77029.1 - 0.0073 15.6 0.8 0.037 13.3 0.1 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2246) rve_3 PF13683.1 EIE77029.1 - 0.0075 15.7 0.2 0.047 13.2 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain UBN2 PF14223.1 EIE77029.1 - 0.061 13.1 0.1 0.21 11.3 0.1 1.9 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type DDE_3 PF13358.1 EIE77031.1 - 1.4e-17 63.8 0.1 4.3e-17 62.2 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE77031.1 - 1.6e-10 40.8 0.4 3.8e-10 39.6 0.2 1.7 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.1 EIE77031.1 - 0.039 14.1 0.0 0.11 12.6 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn helix GerE PF00196.14 EIE77031.1 - 0.14 11.5 0.0 0.32 10.3 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family DDE_3 PF13358.1 EIE77034.1 - 7.3e-20 71.2 0.1 1.3e-19 70.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE77034.1 - 2.2e-08 34.0 2.9 3.1e-08 33.5 0.3 2.4 1 1 1 2 2 2 1 Transposase rve PF00665.21 EIE77034.1 - 0.036 14.1 0.1 0.093 12.8 0.0 1.8 2 0 0 2 2 2 0 Integrase core domain HTH_12 PF08461.5 EIE77034.1 - 0.11 12.2 0.1 0.34 10.6 0.0 1.8 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain HTH_29 PF13551.1 EIE77034.1 - 0.23 11.6 2.9 0.23 11.6 0.8 2.0 2 1 0 2 2 2 0 Winged helix-turn helix DUF1033 PF06279.6 EIE77034.1 - 0.33 10.7 4.6 0.38 10.5 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1033) NFRKB_winged PF14465.1 EIE77034.1 - 0.54 10.1 3.7 5.8 6.8 0.4 2.9 2 1 1 3 3 3 0 NFRKB Winged Helix-like HTH_32 PF13565.1 EIE77034.1 - 0.71 10.7 5.9 0.27 12.0 0.6 2.7 4 0 0 4 4 4 0 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.1 EIE77034.1 - 1.8 7.8 3.8 1.1 8.5 0.1 2.4 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 Transposase_21 PF02992.9 EIE77036.1 - 6.5e-23 80.9 0.1 6.5e-23 80.9 0.1 1.7 2 0 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.1 EIE77036.1 - 1.5e-05 24.4 0.6 3.3e-05 23.3 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) rve PF00665.21 EIE77037.1 - 7.2e-19 68.0 0.0 1.6e-18 66.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain HTH_22 PF13309.1 EIE77037.1 - 0.0033 17.1 0.0 0.023 14.4 0.0 2.5 3 0 0 3 3 3 1 HTH domain zf-H2C2 PF09337.5 EIE77037.1 - 0.03 13.7 0.3 0.058 12.8 0.2 1.5 1 0 0 1 1 1 0 His(2)-Cys(2) zinc finger rve_3 PF13683.1 EIE77037.1 - 0.034 13.6 0.0 0.076 12.5 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain RVT_1 PF00078.22 EIE77039.1 - 5e-09 35.8 0.0 1e-08 34.8 0.0 1.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.12 EIE77040.1 - 2.3e-08 33.9 0.2 4.9e-08 32.9 0.2 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein Asp_protease_2 PF13650.1 EIE77040.1 - 1.1e-07 32.2 0.0 2.7e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.18 EIE77040.1 - 0.00083 19.1 1.3 0.0015 18.3 0.9 1.5 1 0 0 1 1 1 1 Zinc knuckle gag-asp_proteas PF13975.1 EIE77040.1 - 0.0035 17.1 0.0 0.01 15.6 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 EIE77040.1 - 0.02 14.8 0.0 0.039 13.8 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease RVP PF00077.15 EIE77040.1 - 0.025 14.5 0.0 0.062 13.2 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease rve PF00665.21 EIE77041.1 - 3.3e-23 82.0 0.0 2.5e-22 79.2 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 EIE77041.1 - 2.2e-16 59.8 0.0 4.4e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE77041.1 - 2.7e-11 42.9 0.2 6.5e-11 41.7 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.1 EIE77041.1 - 3.1e-06 27.5 0.0 1.5e-05 25.3 0.0 2.3 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.12 EIE77041.1 - 8.6e-06 25.7 1.0 2.1e-05 24.4 0.0 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein UBN2_2 PF14227.1 EIE77041.1 - 3.5e-05 23.3 0.5 0.0011 18.5 0.1 3.5 4 1 0 4 4 4 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EIE77041.1 - 0.00071 19.3 0.7 0.26 11.0 0.1 2.9 3 0 0 3 3 3 2 gag-polypeptide of LTR copia-type gag-asp_proteas PF13975.1 EIE77041.1 - 0.0011 18.7 0.0 0.0022 17.7 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.5 EIE77041.1 - 0.0087 15.4 0.1 0.029 13.7 0.0 2.0 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger gag-asp_proteas PF13975.1 EIE77042.1 - 0.0064 16.2 0.1 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 EIE77042.1 - 0.015 15.1 0.2 0.039 13.8 0.0 1.8 2 0 0 2 2 2 0 Retroviral aspartyl protease Asp_protease PF09668.5 EIE77042.1 - 0.022 14.3 0.0 0.034 13.7 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease Asp_protease_2 PF13650.1 EIE77042.1 - 0.087 13.3 0.0 0.21 12.1 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease Flp_C PF05202.7 EIE77042.1 - 0.14 11.3 0.1 0.23 10.6 0.0 1.4 2 0 0 2 2 2 0 Recombinase Flp protein Chromo PF00385.19 EIE77043.1 - 1.4e-14 53.4 1.8 2.6e-14 52.5 1.3 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain SCP2 PF02036.12 EIE77044.1 - 4.7e-24 84.6 0.8 5.5e-24 84.4 0.5 1.0 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 EIE77044.1 - 0.0002 21.3 0.1 0.00027 20.9 0.1 1.3 1 1 0 1 1 1 1 Alkyl sulfatase C-terminal Toxin_20 PF08089.6 EIE77044.1 - 0.19 11.6 0.6 0.31 10.9 0.4 1.5 1 1 0 1 1 1 0 Huwentoxin-II family Pribosyltran PF00156.22 EIE77045.1 - 1.9e-07 30.8 0.0 4e-07 29.8 0.0 1.5 1 1 0 1 1 1 1 Phosphoribosyl transferase domain MaoC_dehydratas PF01575.14 EIE77047.1 - 1.5e-26 92.1 0.0 2.5e-26 91.4 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 EIE77047.1 - 0.00034 20.3 0.0 0.0014 18.3 0.0 2.0 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase TRAM_LAG1_CLN8 PF03798.11 EIE77048.1 - 3.8e-37 127.7 26.0 4.5e-37 127.5 18.0 1.0 1 0 0 1 1 1 1 TLC domain Tmemb_9 PF05434.6 EIE77048.1 - 0.12 12.1 0.5 0.3 10.8 0.1 1.8 2 0 0 2 2 2 0 TMEM9 DUF914 PF06027.7 EIE77049.1 - 5.1e-105 351.0 16.6 6.5e-105 350.6 11.5 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 EIE77049.1 - 4.3e-05 23.5 27.8 7.8e-05 22.7 4.6 2.5 2 1 1 3 3 3 2 EamA-like transporter family TPT PF03151.11 EIE77049.1 - 0.00018 21.2 21.8 0.004 16.8 0.3 2.5 3 0 0 3 3 3 2 Triose-phosphate Transporter family DUF106 PF01956.11 EIE77049.1 - 0.05 13.1 1.4 0.34 10.4 0.0 2.4 2 0 0 2 2 2 0 Integral membrane protein DUF106 UAA PF08449.6 EIE77049.1 - 0.32 9.8 22.5 0.8 8.5 15.5 1.7 1 1 0 1 1 1 0 UAA transporter family CopD PF05425.8 EIE77049.1 - 9.8 6.4 10.9 2.9 8.1 0.5 3.0 3 1 1 4 4 4 0 Copper resistance protein D SNARE PF05739.14 EIE77050.1 - 8.8e-14 50.9 5.3 2.2e-13 49.6 3.7 1.8 1 0 0 1 1 1 1 SNARE domain PX PF00787.19 EIE77050.1 - 1.2e-13 50.7 0.2 2.5e-13 49.8 0.1 1.5 1 0 0 1 1 1 1 PX domain MAGSP PF03082.9 EIE77050.1 - 0.028 13.8 3.8 2 7.7 0.1 2.1 2 0 0 2 2 2 0 Male accessory gland secretory protein HAT PF02184.11 EIE77050.1 - 0.22 11.2 2.2 0.48 10.2 1.6 1.5 1 0 0 1 1 1 0 HAT (Half-A-TPR) repeat Nipped-B_C PF12830.2 EIE77050.1 - 0.29 10.7 3.3 0.16 11.6 0.9 1.5 2 0 0 2 2 2 0 Sister chromatid cohesion C-terminus FliJ PF02050.11 EIE77050.1 - 3.4 7.7 13.2 7.6 6.6 5.7 2.7 2 1 1 3 3 3 0 Flagellar FliJ protein DUF3318 PF11780.3 EIE77051.1 - 0.064 12.8 0.3 0.4 10.2 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3318) DUF4210 PF13915.1 EIE77052.1 - 7.9e-19 67.7 0.0 1.6e-18 66.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.1 EIE77052.1 - 4e-18 65.0 0.4 1e-17 63.7 0.3 1.8 1 0 0 1 1 1 1 Chromosome segregation during meiosis HSDR_N PF04313.9 EIE77052.1 - 0.13 12.0 0.2 0.19 11.4 0.1 1.2 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) tRNA_anti-codon PF01336.20 EIE77053.1 - 0.023 14.5 0.1 0.039 13.7 0.1 1.4 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain BRCT PF00533.21 EIE77054.1 - 0.013 15.6 2.2 1.4 9.1 0.4 2.4 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain Asp PF00026.18 EIE77055.1 - 1.8e-91 306.6 9.9 2.9e-91 306.0 6.8 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIE77055.1 - 1.8e-08 34.5 3.5 4e-07 30.1 1.0 3.1 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EIE77055.1 - 2.3e-05 24.7 4.6 0.0089 16.5 0.2 3.4 3 1 0 3 3 3 2 Aspartyl protease TAXi_C PF14541.1 EIE77055.1 - 0.0023 17.4 0.6 0.18 11.3 0.0 2.7 2 1 0 3 3 3 1 Xylanase inhibitor C-terminal Big_1 PF02369.11 EIE77055.1 - 0.17 11.8 1.4 0.82 9.6 0.1 2.6 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 1) TRAPP PF04051.11 EIE77056.1 - 4.8e-41 139.8 0.0 5.3e-41 139.6 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Asp PF00026.18 EIE77058.1 - 1.8e-91 306.6 9.9 2.9e-91 306.0 6.8 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIE77058.1 - 1.8e-08 34.5 3.5 4e-07 30.1 1.0 3.1 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EIE77058.1 - 2.3e-05 24.7 4.6 0.0089 16.5 0.2 3.4 3 1 0 3 3 3 2 Aspartyl protease TAXi_C PF14541.1 EIE77058.1 - 0.0023 17.4 0.6 0.18 11.3 0.0 2.7 2 1 0 3 3 3 1 Xylanase inhibitor C-terminal Big_1 PF02369.11 EIE77058.1 - 0.17 11.8 1.4 0.82 9.6 0.1 2.6 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 1) Abhydrolase_5 PF12695.2 EIE77059.1 - 2.5e-08 33.8 0.0 0.00068 19.4 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EIE77059.1 - 3.4e-07 29.7 0.0 6.2e-05 22.3 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family COesterase PF00135.23 EIE77059.1 - 0.00022 20.1 0.4 0.00073 18.3 0.2 1.7 1 1 1 2 2 2 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EIE77059.1 - 0.0027 17.2 0.0 0.06 12.9 0.0 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EIE77059.1 - 0.03 14.1 0.0 1.2 8.9 0.0 2.3 1 1 1 2 2 2 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EIE77059.1 - 0.057 13.2 0.0 0.25 11.2 0.0 2.0 2 0 0 2 2 2 0 Putative lysophospholipase PAF-AH_p_II PF03403.8 EIE77059.1 - 0.11 10.7 0.0 0.38 8.9 0.0 1.8 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II SHOCT PF09851.4 EIE77060.1 - 0.051 13.0 0.0 0.18 11.3 0.0 1.9 1 0 0 1 1 1 0 Short C-terminal domain DAGK_acc PF00609.14 EIE77061.1 - 2.4e-15 57.0 0.0 5e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.19 EIE77061.1 - 3.3e-11 42.7 0.0 6.3e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain MAM33 PF02330.11 EIE77062.1 - 5.4e-29 101.4 8.1 7.1e-29 101.0 5.6 1.1 1 0 0 1 1 1 1 Mitochondrial glycoprotein Ecl1 PF12855.2 EIE77065.1 - 1.5e-07 30.6 3.8 2.3e-07 30.0 2.6 1.3 1 0 0 1 1 1 1 Life-span regulatory factor zf-MYND PF01753.13 EIE77065.1 - 0.07 13.0 3.2 0.11 12.3 2.2 1.3 1 0 0 1 1 1 0 MYND finger GPI-anchored PF10342.4 EIE77066.1 - 4.1e-12 46.4 3.2 4.1e-12 46.4 2.2 2.3 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Tissue_fac PF01108.12 EIE77066.1 - 0.025 14.2 0.0 0.058 13.1 0.0 1.7 1 0 0 1 1 1 0 Tissue factor bZIP_1 PF00170.16 EIE77068.1 - 3.2e-09 36.6 13.6 3.2e-09 36.6 9.4 2.0 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EIE77068.1 - 1.8e-07 30.8 14.4 3.7e-07 29.8 10.0 1.6 1 0 0 1 1 1 1 Basic region leucine zipper Glyco_trans_4_3 PF12000.3 EIE77068.1 - 0.044 13.4 0.0 0.064 12.8 0.0 1.2 1 0 0 1 1 1 0 Gkycosyl transferase family 4 group DUF737 PF05300.6 EIE77068.1 - 0.44 10.4 13.9 0.88 9.5 9.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF737) bZIP_Maf PF03131.12 EIE77068.1 - 6.4 7.1 14.0 0.36 11.1 5.2 2.0 1 1 1 2 2 2 0 bZIP Maf transcription factor Nop14 PF04147.7 EIE77069.1 - 5.8e-244 811.8 55.4 6.9e-244 811.6 38.4 1.0 1 0 0 1 1 1 1 Nop14-like family PWWP PF00855.12 EIE77070.1 - 1.3e-16 60.5 0.2 1.3e-16 60.5 0.1 3.0 3 0 0 3 3 3 1 PWWP domain Med26 PF08711.6 EIE77070.1 - 1.1e-06 27.9 0.0 2.5e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain BSP_II PF05432.6 EIE77070.1 - 0.0097 15.2 17.3 0.014 14.6 12.0 1.2 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) CDC45 PF02724.9 EIE77070.1 - 0.023 12.7 14.1 0.032 12.2 9.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.2 EIE77070.1 - 0.16 9.6 8.1 0.16 9.6 5.6 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein TP53IP5 PF15331.1 EIE77070.1 - 1.2 8.9 14.9 2 8.2 10.3 1.5 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Myc_N PF01056.13 EIE77070.1 - 2.8 7.0 20.1 0.34 10.0 10.7 1.7 1 1 1 2 2 2 0 Myc amino-terminal region DUF4203 PF13886.1 EIE77071.1 - 7.9e-07 28.7 13.7 9.6e-07 28.4 9.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) CopD PF05425.8 EIE77071.1 - 2.5 8.3 8.8 4.4 7.5 5.9 1.5 1 1 0 1 1 1 0 Copper resistance protein D DUF4131 PF13567.1 EIE77071.1 - 6.1 6.2 11.1 14 5.0 7.5 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) TPP_enzyme_N PF02776.13 EIE77072.1 - 1.8e-28 99.1 0.0 4.4e-28 97.9 0.0 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EIE77072.1 - 7.1e-24 84.1 0.0 1.5e-23 83.1 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EIE77072.1 - 9.2e-19 67.5 0.0 2.1e-18 66.3 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain CO_dh PF02552.11 EIE77072.1 - 0.097 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit Formyl_trans_N PF00551.14 EIE77073.1 - 1.5e-52 177.7 0.1 2e-52 177.3 0.1 1.0 1 0 0 1 1 1 1 Formyl transferase NMO PF03060.10 EIE77075.1 - 4.9e-65 219.8 0.1 5.6e-65 219.6 0.1 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.13 EIE77075.1 - 2.5e-07 29.8 0.1 3.3e-05 22.9 0.0 2.4 2 0 0 2 2 2 2 FMN-dependent dehydrogenase IMPDH PF00478.20 EIE77075.1 - 8.3e-07 28.2 0.0 0.00037 19.4 0.0 2.1 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.16 EIE77075.1 - 5e-06 25.9 0.0 9e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Histidine biosynthesis protein DHO_dh PF01180.16 EIE77075.1 - 5.4e-05 22.2 0.0 0.00012 21.1 0.0 1.7 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase Glu_synthase PF01645.12 EIE77075.1 - 0.00021 20.3 0.5 0.00043 19.2 0.4 1.6 1 1 0 1 1 1 1 Conserved region in glutamate synthase TMP-TENI PF02581.12 EIE77075.1 - 0.0011 18.1 0.2 0.0035 16.4 0.1 1.8 1 1 0 1 1 1 1 Thiamine monophosphate synthase/TENI ThiG PF05690.9 EIE77075.1 - 0.016 14.3 0.1 0.035 13.1 0.0 1.5 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG Trp_syntA PF00290.15 EIE77075.1 - 0.071 11.6 0.0 0.24 9.9 0.0 1.8 2 0 0 2 2 2 0 Tryptophan synthase alpha chain Na_Ca_ex PF01699.19 EIE77076.1 - 8.1e-43 145.3 42.0 1e-23 83.5 11.2 2.6 3 0 0 3 3 3 2 Sodium/calcium exchanger protein DUF4199 PF13858.1 EIE77076.1 - 0.0074 16.2 2.2 0.0074 16.2 1.5 4.5 2 2 2 5 5 5 2 Protein of unknown function (DUF4199) Inhibitor_I9 PF05922.11 EIE77077.1 - 1.9e-09 37.9 0.2 2.1e-09 37.8 0.1 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I9 Methyltransf_11 PF08241.7 EIE77078.1 - 1.1e-13 51.4 0.0 1.7e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIE77078.1 - 2.1e-11 43.6 0.0 3.1e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIE77078.1 - 1.3e-09 37.9 0.0 1.9e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIE77078.1 - 1.7e-08 34.7 0.0 3e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIE77078.1 - 2.4e-07 31.3 0.0 4.9e-07 30.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIE77078.1 - 7e-07 29.6 0.0 1.6e-06 28.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EIE77078.1 - 4.4e-05 23.2 0.0 6.7e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase Ubie_methyltran PF01209.13 EIE77078.1 - 8.2e-05 21.8 0.0 0.00017 20.7 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EIE77078.1 - 0.00018 21.5 0.0 0.00028 20.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EIE77078.1 - 0.00024 20.2 0.0 0.00044 19.3 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase TehB PF03848.9 EIE77078.1 - 0.00082 18.5 0.0 0.002 17.3 0.0 1.6 1 1 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_29 PF03141.11 EIE77078.1 - 0.0025 16.2 0.0 0.0047 15.3 0.0 1.4 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MetW PF07021.7 EIE77078.1 - 0.027 13.8 0.0 0.037 13.4 0.0 1.1 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_2 PF00891.13 EIE77078.1 - 0.047 12.8 0.0 0.047 12.8 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Pyridox_oxase_2 PF12766.2 EIE77078.1 - 0.099 12.9 0.1 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Pkinase PF00069.20 EIE77079.1 - 5.4e-66 222.3 0.0 7.4e-66 221.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE77079.1 - 3.8e-32 111.3 0.0 5.2e-32 110.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EIE77079.1 - 8.1e-09 35.4 0.0 2e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 EIE77079.1 - 1.3e-06 27.5 0.0 2.6e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EIE77079.1 - 0.00042 19.4 0.1 0.00072 18.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIE77079.1 - 0.015 15.0 0.0 0.027 14.1 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.17 EIE77079.1 - 0.015 14.6 0.4 0.033 13.5 0.2 1.5 1 1 0 1 1 1 0 RIO1 family tRNA-synt_His PF13393.1 EIE77080.1 - 1.1e-39 136.3 0.0 2.2e-35 122.2 0.0 2.2 2 0 0 2 2 2 2 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 EIE77080.1 - 3e-21 75.7 0.0 6.7e-21 74.6 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EIE77080.1 - 9.9e-15 54.2 0.2 2.1e-14 53.1 0.1 1.6 1 0 0 1 1 1 1 Anticodon binding domain WHEP-TRS PF00458.15 EIE77080.1 - 2.2e-14 52.8 5.3 2.2e-14 52.8 3.7 2.2 2 0 0 2 2 2 1 WHEP-TRS domain tRNA-synt_2 PF00152.15 EIE77080.1 - 7.2e-06 25.0 0.1 0.00073 18.4 0.1 2.7 2 1 0 2 2 2 1 tRNA synthetases class II (D, K and N) HGTP_anticodon2 PF12745.2 EIE77080.1 - 0.05 12.7 0.1 0.05 12.7 0.1 1.5 2 0 0 2 2 2 0 Anticodon binding domain of tRNAs DUF1820 PF08850.6 EIE77080.1 - 0.096 12.8 0.1 0.35 10.9 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1820) Usp PF00582.21 EIE77081.1 - 3.1e-19 69.5 0.0 9.5e-19 67.9 0.0 1.8 2 0 0 2 2 2 1 Universal stress protein family PCI_Csn8 PF10075.4 EIE77082.1 - 2.3e-06 27.4 0.2 2.6e-06 27.2 0.1 1.3 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 EIE77082.1 - 2.5e-06 27.1 0.1 3.5e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Toxin_10 PF05431.6 EIE77082.1 - 0.058 13.0 0.1 0.058 13.0 0.1 1.2 1 0 0 1 1 1 0 Insecticidal Crystal Toxin, P42 Hexapep PF00132.19 EIE77083.1 - 6.8e-14 50.6 16.3 3e-10 39.1 6.0 3.7 4 0 0 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EIE77083.1 - 2e-09 36.8 17.0 4.4e-08 32.5 6.1 2.9 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Ribosomal_L38e PF01781.13 EIE77084.1 - 1.6e-34 117.4 4.4 1.7e-34 117.3 3.0 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family TFIID_90kDa PF04494.10 EIE77084.1 - 0.0089 16.0 0.1 0.0093 16.0 0.1 1.1 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit MFS_1 PF07690.11 EIE77086.1 - 2e-31 109.0 69.0 2.4e-28 98.8 30.5 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EIE77086.1 - 1e-08 34.0 11.6 1e-08 34.0 8.1 3.8 1 1 2 3 3 3 3 MFS/sugar transport protein SH3_1 PF00018.23 EIE77087.1 - 2.8e-13 49.0 0.0 3.8e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EIE77087.1 - 5.3e-11 41.8 0.0 7.2e-11 41.4 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EIE77087.1 - 9.9e-11 41.0 0.0 1.4e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 EIE77087.1 - 0.0013 18.9 0.0 0.0038 17.3 0.0 1.7 2 0 0 2 2 2 1 Bacterial SH3 domain SH3_4 PF06347.8 EIE77087.1 - 0.013 15.0 0.9 0.02 14.4 0.0 1.6 2 0 0 2 2 2 0 Bacterial SH3 domain AAA_19 PF13245.1 EIE77087.1 - 0.026 14.2 0.3 0.037 13.7 0.2 1.2 1 0 0 1 1 1 0 Part of AAA domain Glyco_hydro_9 PF00759.14 EIE77087.1 - 0.067 12.0 0.4 0.075 11.9 0.3 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 zf-C4H2 PF10146.4 EIE77087.1 - 0.31 11.0 2.2 0.38 10.7 1.5 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein DUF3108 PF11306.3 EIE77087.1 - 2.2 7.8 7.5 16 5.0 3.5 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF3108) Ras PF00071.17 EIE77088.1 - 8.5e-63 210.5 0.2 1.1e-62 210.1 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIE77088.1 - 1.6e-21 77.0 0.1 2.7e-21 76.2 0.1 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIE77088.1 - 1.4e-13 50.5 0.1 2.2e-13 49.8 0.1 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EIE77088.1 - 4.5e-07 29.8 0.0 8.3e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EIE77088.1 - 1.6e-05 24.4 0.2 5.7e-05 22.6 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EIE77088.1 - 6e-05 23.1 0.1 0.00022 21.3 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_15 PF13175.1 EIE77088.1 - 0.00014 21.0 0.0 0.00027 20.0 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain Gtr1_RagA PF04670.7 EIE77088.1 - 0.00026 20.2 0.1 0.00041 19.5 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EIE77088.1 - 0.0011 18.2 0.1 0.0026 17.0 0.0 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_14 PF13173.1 EIE77088.1 - 0.0018 18.1 0.1 0.0046 16.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EIE77088.1 - 0.0055 15.9 0.1 0.014 14.5 0.1 1.9 1 1 0 1 1 1 1 Protein of unknown function, DUF258 PduV-EutP PF10662.4 EIE77088.1 - 0.0086 15.5 0.0 0.027 13.9 0.0 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 EIE77088.1 - 0.0092 15.9 0.2 0.03 14.3 0.2 1.9 1 1 0 1 1 1 1 AAA ATPase domain FeoB_N PF02421.13 EIE77088.1 - 0.013 14.8 0.0 0.16 11.1 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_24 PF13479.1 EIE77088.1 - 0.017 14.7 0.2 0.028 13.9 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_32 PF13654.1 EIE77088.1 - 0.025 13.2 0.2 0.29 9.7 0.0 2.2 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.22 EIE77088.1 - 0.032 14.5 0.1 0.05 13.8 0.1 1.6 1 1 0 1 1 1 0 ABC transporter SpoIIID PF12116.3 EIE77088.1 - 0.049 13.5 0.1 1.4 8.8 0.0 2.3 2 0 0 2 2 2 0 Stage III sporulation protein D YtzH PF14165.1 EIE77088.1 - 0.059 13.6 0.3 0.34 11.1 0.1 2.1 2 0 0 2 2 2 0 YtzH-like protein cobW PF02492.14 EIE77088.1 - 0.076 12.4 0.1 0.13 11.6 0.1 1.8 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.9 EIE77088.1 - 0.085 12.5 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.7 EIE77088.1 - 0.091 12.4 0.0 0.28 10.8 0.0 1.7 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.1 EIE77088.1 - 0.099 12.5 0.1 0.27 11.2 0.1 2.0 1 1 0 1 1 1 0 AAA domain LSM14 PF12701.2 EIE77089.1 - 1.1e-36 124.5 0.0 1.1e-36 124.5 0.0 2.2 2 0 0 2 2 2 1 Scd6-like Sm domain FDF PF09532.5 EIE77089.1 - 5.3e-13 49.4 15.5 5.3e-13 49.4 10.7 4.2 2 1 1 3 3 3 1 FDF domain SM-ATX PF14438.1 EIE77089.1 - 5.4e-05 23.0 0.0 0.00014 21.6 0.0 1.7 1 0 0 1 1 1 1 Ataxin 2 SM domain PAT1 PF09770.4 EIE77089.1 - 0.067 11.4 45.0 0.0092 14.2 28.1 1.7 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 EIE77089.1 - 0.57 10.0 33.3 0.81 9.5 23.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Xan_ur_permease PF00860.15 EIE77090.1 - 1.4e-76 257.5 40.2 5.1e-75 252.3 27.9 2.0 1 1 0 1 1 1 1 Permease family HSF_DNA-bind PF00447.12 EIE77091.1 - 4.1e-28 97.5 0.3 4.1e-28 97.5 0.2 2.7 3 1 0 3 3 3 1 HSF-type DNA-binding Hrs_helical PF12210.3 EIE77091.1 - 0.11 12.7 2.3 0.16 12.2 0.7 2.0 2 0 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate IPPT PF01715.12 EIE77092.1 - 2.4e-26 92.2 1.4 1.1e-24 86.9 0.5 2.1 1 1 1 2 2 2 2 IPP transferase HMGL-like PF00682.14 EIE77093.1 - 4.9e-44 150.7 0.1 6.2e-44 150.4 0.1 1.1 1 0 0 1 1 1 1 HMGL-like Aldolase_II PF00596.16 EIE77093.1 - 0.023 14.3 0.1 0.04 13.5 0.1 1.3 1 0 0 1 1 1 0 Class II Aldolase and Adducin N-terminal domain NRDE-2 PF08424.5 EIE77094.1 - 2.8e-85 286.0 11.8 3.6e-83 279.1 0.2 3.7 3 1 1 4 4 4 4 NRDE-2, necessary for RNA interference TPR_14 PF13428.1 EIE77094.1 - 1.6e-05 25.1 0.2 15 6.5 0.0 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat FixH PF05751.6 EIE77094.1 - 0.053 13.3 0.3 0.12 12.1 0.2 1.5 1 0 0 1 1 1 0 FixH TPR_19 PF14559.1 EIE77094.1 - 0.062 13.6 5.1 40 4.6 0.0 4.8 5 1 0 5 5 5 0 Tetratricopeptide repeat Pkinase PF00069.20 EIE77096.1 - 4e-30 104.8 0.0 4.7e-30 104.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE77096.1 - 2.3e-09 36.7 0.0 4.4e-09 35.8 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Reo_sigmaC PF04582.7 EIE77097.1 - 0.0016 17.6 2.0 0.0016 17.6 1.4 2.1 1 1 1 2 2 2 1 Reovirus sigma C capsid protein AAA_13 PF13166.1 EIE77097.1 - 0.013 14.0 32.7 0.016 13.7 22.7 1.1 1 0 0 1 1 1 0 AAA domain Occludin_ELL PF07303.8 EIE77097.1 - 0.21 12.3 30.9 0.5 11.1 7.5 3.3 1 1 2 3 3 3 0 Occludin homology domain FlxA PF14282.1 EIE77097.1 - 0.34 10.8 42.7 0.16 11.8 12.5 3.3 2 1 1 3 3 3 0 FlxA-like protein APG6 PF04111.7 EIE77097.1 - 0.42 9.6 45.0 0.27 10.2 12.3 3.0 1 1 2 3 3 3 0 Autophagy protein Apg6 Syntaxin-6_N PF09177.6 EIE77097.1 - 0.51 10.7 27.8 0.041 14.2 3.1 3.6 1 1 3 4 4 4 0 Syntaxin 6, N-terminal FUSC PF04632.7 EIE77097.1 - 0.84 7.9 3.1 1.1 7.6 2.2 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family GAS PF13851.1 EIE77097.1 - 1.1 8.3 46.0 0.87 8.7 18.8 3.2 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding DUF501 PF04417.7 EIE77097.1 - 1.4 8.7 15.9 0.66 9.8 2.6 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF501) UPF0184 PF03670.8 EIE77097.1 - 1.8 8.7 8.0 0.28 11.3 0.2 2.8 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0184) DUF4144 PF13642.1 EIE77097.1 - 2.6 8.4 7.3 1.9 8.9 2.9 2.5 1 1 0 1 1 1 0 protein structure with unknown function FRG PF08867.6 EIE77097.1 - 4.5 7.8 9.2 1.1 9.7 0.1 2.9 2 1 0 2 2 2 0 FRG domain DUF3584 PF12128.3 EIE77097.1 - 5.2 4.2 37.5 0.92 6.7 10.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) ERM PF00769.14 EIE77097.1 - 7.5 6.0 45.2 1.4 8.4 16.1 3.1 1 1 2 3 3 3 0 Ezrin/radixin/moesin family DUF4510 PF14971.1 EIE77097.1 - 7.5 6.6 13.6 7.6 6.6 0.3 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4510) Tropomyosin_1 PF12718.2 EIE77097.1 - 7.6 6.3 48.0 0.21 11.4 7.6 3.3 2 1 0 3 3 3 0 Tropomyosin like Nucleopor_Nup85 PF07575.8 EIE77098.1 - 1.8e-12 46.2 7.6 7.1e-11 41.0 0.1 3.0 2 1 0 2 2 2 2 Nup85 Nucleoporin PLDc_2 PF13091.1 EIE77099.1 - 2.4e-26 91.9 2.0 4.8e-26 90.9 0.1 2.3 3 0 0 3 3 3 1 PLD-like domain DUF1669 PF07894.7 EIE77099.1 - 0.00058 19.1 6.1 0.0025 17.0 0.0 2.9 2 1 0 3 3 3 2 Protein of unknown function (DUF1669) PLDc PF00614.17 EIE77099.1 - 0.013 15.3 0.1 0.028 14.2 0.1 1.6 1 0 0 1 1 1 0 Phospholipase D Active site motif Cyclin_N PF00134.18 EIE77100.1 - 1.7e-17 63.1 0.1 5.6e-17 61.4 0.0 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin PF08613.6 EIE77100.1 - 4.7e-11 43.3 0.0 5.7e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Cyclin Abhydrolase_3 PF07859.8 EIE77101.1 - 1.3e-53 181.6 0.0 1.7e-53 181.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EIE77101.1 - 1.6e-06 27.0 0.0 2.2e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) COesterase PF00135.23 EIE77101.1 - 4e-05 22.5 0.0 0.029 13.0 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family DLH PF01738.13 EIE77101.1 - 0.0017 17.6 0.0 0.017 14.4 0.0 2.0 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EIE77101.1 - 0.003 17.3 0.0 0.011 15.4 0.0 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EIE77101.1 - 0.005 15.7 0.0 0.0099 14.7 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_6 PF12697.2 EIE77101.1 - 0.02 14.7 0.0 0.048 13.5 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EIE77101.1 - 0.039 13.1 0.0 0.39 9.9 0.0 2.0 1 1 0 1 1 1 0 Prolyl oligopeptidase family DUF2584 PF10763.4 EIE77102.1 - 0.02 14.7 0.0 0.022 14.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2584) AAA_5 PF07728.9 EIE77103.1 - 8.2e-129 424.1 0.0 1.5e-28 99.2 0.0 8.8 8 0 0 8 8 8 8 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EIE77103.1 - 1.1e-32 112.3 0.0 2.6e-08 33.5 0.0 6.8 7 0 0 7 7 6 4 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 EIE77103.1 - 3e-28 98.6 0.2 0.00011 22.3 0.0 6.9 6 0 0 6 6 6 4 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EIE77103.1 - 7.3e-25 88.1 0.0 0.0011 19.7 0.0 7.2 6 0 0 6 6 6 4 AAA domain AAA_14 PF13173.1 EIE77103.1 - 1.1e-23 83.5 0.9 3.9e-05 23.5 0.0 8.4 8 1 0 9 9 7 4 AAA domain AAA_22 PF13401.1 EIE77103.1 - 5.7e-23 81.5 0.6 0.0022 18.1 0.0 8.0 7 0 0 7 7 7 4 AAA domain AAA_18 PF13238.1 EIE77103.1 - 2.6e-22 79.5 1.1 0.003 17.8 0.0 7.1 6 0 0 6 6 6 4 AAA domain Sigma54_activat PF00158.21 EIE77103.1 - 6.8e-20 71.2 0.8 0.0022 17.4 0.0 7.4 8 0 0 8 8 6 4 Sigma-54 interaction domain AAA_16 PF13191.1 EIE77103.1 - 7.3e-20 71.7 7.1 0.0002 21.3 0.2 7.4 6 2 0 6 6 6 4 AAA ATPase domain Sigma54_activ_2 PF14532.1 EIE77103.1 - 3.6e-19 69.1 0.1 0.00079 19.4 0.0 6.6 6 0 0 6 6 6 3 Sigma-54 interaction domain AAA_33 PF13671.1 EIE77103.1 - 4.3e-19 68.8 0.6 0.098 12.5 0.0 7.8 6 2 0 6 6 6 5 AAA domain ABC_tran PF00005.22 EIE77103.1 - 7.8e-18 65.0 1.9 0.0086 16.3 0.0 6.8 6 0 0 6 6 6 4 ABC transporter UPF0079 PF02367.12 EIE77103.1 - 5.8e-17 61.4 2.7 0.014 14.9 0.0 6.5 6 0 0 6 6 6 3 Uncharacterised P-loop hydrolase UPF0079 Zeta_toxin PF06414.7 EIE77103.1 - 1.3e-16 60.2 0.1 0.027 13.5 0.0 6.7 6 0 0 6 6 6 4 Zeta toxin AAA_19 PF13245.1 EIE77103.1 - 9.5e-14 50.9 4.7 0.081 12.6 0.0 6.4 6 0 0 6 6 6 3 Part of AAA domain AAA_30 PF13604.1 EIE77103.1 - 4.9e-13 49.1 0.0 0.35 10.4 0.0 7.2 7 0 0 7 7 6 3 AAA domain AAA_28 PF13521.1 EIE77103.1 - 1.3e-12 48.0 7.9 0.14 12.0 0.0 6.6 6 0 0 6 6 6 3 AAA domain AAA_29 PF13555.1 EIE77103.1 - 4.2e-12 45.4 1.3 0.67 9.5 0.0 6.7 6 0 0 6 6 6 1 P-loop containing region of AAA domain Miro PF08477.8 EIE77103.1 - 2.1e-11 44.3 5.7 1.1 9.8 0.0 7.0 7 0 0 7 7 6 1 Miro-like protein T2SE PF00437.15 EIE77103.1 - 2.2e-11 43.1 4.7 0.1 11.4 0.0 6.2 6 0 0 6 6 6 3 Type II/IV secretion system protein DUF258 PF03193.11 EIE77103.1 - 3.7e-11 42.4 5.5 0.43 9.7 0.0 6.3 6 0 0 6 6 6 2 Protein of unknown function, DUF258 MobB PF03205.9 EIE77103.1 - 8.8e-11 41.6 2.5 0.26 10.9 0.0 6.3 6 0 0 6 6 6 2 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 EIE77103.1 - 8.6e-10 38.7 5.2 0.32 11.2 0.0 6.7 7 0 0 7 7 6 2 RNA helicase PduV-EutP PF10662.4 EIE77103.1 - 5.5e-09 35.6 4.0 0.023 14.1 0.0 5.8 6 0 0 6 6 6 2 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.7 EIE77103.1 - 5.9e-09 35.8 8.9 0.06 13.0 0.0 6.6 7 0 0 7 7 6 2 NACHT domain DUF815 PF05673.8 EIE77103.1 - 6.8e-09 35.0 2.3 0.44 9.4 0.0 5.8 6 0 0 6 6 6 3 Protein of unknown function (DUF815) AAA_25 PF13481.1 EIE77103.1 - 7.5e-09 35.2 3.7 0.088 12.2 0.0 5.3 6 0 0 6 6 5 3 AAA domain AAA_2 PF07724.9 EIE77103.1 - 9.5e-09 35.3 0.0 5.2 6.9 0.0 6.9 6 0 0 6 6 6 0 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 EIE77103.1 - 4.4e-08 32.4 0.2 0.48 9.4 0.0 6.4 7 0 0 7 7 6 1 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 EIE77103.1 - 5.9e-08 32.1 4.1 13 4.8 0.0 8.3 9 0 0 9 9 8 0 Magnesium chelatase, subunit ChlI AAA_23 PF13476.1 EIE77103.1 - 1e-07 32.4 7.5 8.9 6.5 0.0 7.0 6 1 0 6 6 6 0 AAA domain cobW PF02492.14 EIE77103.1 - 3.7e-07 29.7 4.0 7.5 5.9 0.0 6.2 6 0 0 6 6 6 0 CobW/HypB/UreG, nucleotide-binding domain AAA_11 PF13086.1 EIE77103.1 - 4.2e-07 29.7 0.1 21 4.5 0.0 6.2 6 0 0 6 6 6 0 AAA domain Rad17 PF03215.10 EIE77103.1 - 6.1e-07 28.4 0.4 0.63 8.6 0.0 4.7 5 0 0 5 5 5 2 Rad17 cell cycle checkpoint protein Viral_helicase1 PF01443.13 EIE77103.1 - 3.1e-06 26.8 0.4 0.54 9.7 0.0 5.1 5 0 0 5 5 5 1 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.12 EIE77103.1 - 3.3e-06 26.6 0.6 0.88 8.9 0.0 5.8 6 0 0 6 6 6 1 IstB-like ATP binding protein SRP54 PF00448.17 EIE77103.1 - 1.2e-05 24.8 9.8 0.15 11.4 0.0 5.3 6 0 0 6 6 5 2 SRP54-type protein, GTPase domain SRPRB PF09439.5 EIE77103.1 - 1.4e-05 24.4 4.4 0.16 11.2 0.1 5.7 6 0 0 6 6 6 1 Signal recognition particle receptor beta subunit AAA_24 PF13479.1 EIE77103.1 - 1.7e-05 24.5 0.9 18 4.8 0.0 5.5 5 0 0 5 5 5 0 AAA domain MMR_HSR1 PF01926.18 EIE77103.1 - 1.8e-05 24.6 1.2 5 7.1 0.0 6.0 6 0 0 6 6 6 0 50S ribosome-binding GTPase CPT PF07931.7 EIE77103.1 - 2.5e-05 23.9 8.5 0.13 11.8 0.1 7.1 7 2 0 7 7 5 1 Chloramphenicol phosphotransferase-like protein NTPase_1 PF03266.10 EIE77103.1 - 0.0001 22.0 4.5 2.7 7.6 0.1 5.7 6 0 0 6 6 4 0 NTPase ResIII PF04851.10 EIE77103.1 - 0.00013 21.8 6.2 0.16 11.7 0.0 5.5 6 0 0 6 6 6 1 Type III restriction enzyme, res subunit AAA_21 PF13304.1 EIE77103.1 - 0.00015 21.8 0.0 0.41 10.5 0.0 4.7 4 0 0 4 4 4 1 AAA domain DEAD PF00270.24 EIE77103.1 - 0.0003 20.3 0.4 5.5 6.4 0.0 4.9 5 0 0 5 5 4 0 DEAD/DEAH box helicase ATP-synt_ab PF00006.20 EIE77103.1 - 0.00035 20.1 0.0 4.4 6.7 0.0 4.0 4 2 0 4 4 3 0 ATP synthase alpha/beta family, nucleotide-binding domain VirE PF05272.6 EIE77103.1 - 0.0011 18.4 0.3 0.26 10.7 0.0 4.2 5 0 0 5 5 4 1 Virulence-associated protein E PRK PF00485.13 EIE77103.1 - 0.0015 18.1 2.3 6.8 6.1 0.0 5.2 6 0 0 6 6 4 0 Phosphoribulokinase / Uridine kinase family ATP_bind_1 PF03029.12 EIE77103.1 - 0.0018 17.8 9.1 1.2 8.6 0.0 5.3 6 0 0 6 6 5 1 Conserved hypothetical ATP binding protein KaiC PF06745.8 EIE77103.1 - 0.002 17.2 0.9 5.2 6.1 0.0 4.4 5 0 0 5 5 4 0 KaiC Thymidylate_kin PF02223.12 EIE77103.1 - 0.0037 16.6 2.8 12 5.2 0.0 5.1 6 0 0 6 6 4 0 Thymidylate kinase MCM PF00493.18 EIE77103.1 - 0.0047 15.7 0.2 7.4 5.2 0.0 4.1 4 0 0 4 4 4 0 MCM2/3/5 family S-AdoMet_synt_C PF02773.11 EIE77103.1 - 0.0077 15.9 0.0 0.16 11.6 0.0 2.5 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain AAA_6 PF12774.2 EIE77103.1 - 0.025 14.1 0.1 15 5.0 0.0 4.6 6 0 0 6 6 4 0 Hydrolytic ATP binding site of dynein motor region D1 SKI PF01202.17 EIE77103.1 - 0.032 14.0 3.6 2.4 7.9 0.0 4.9 6 0 0 6 6 4 0 Shikimate kinase FtsK_SpoIIIE PF01580.13 EIE77103.1 - 0.036 13.5 0.8 3.6 6.9 0.0 3.6 4 0 0 4 4 3 0 FtsK/SpoIIIE family IPT PF01745.11 EIE77103.1 - 0.07 12.2 2.5 4.9 6.2 0.0 4.1 5 0 0 5 5 3 0 Isopentenyl transferase CbiA PF01656.18 EIE77103.1 - 0.13 11.6 0.8 6.5 6.1 0.0 3.6 4 0 0 4 4 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain MCP_N PF05581.7 EIE77104.1 - 0.0072 16.4 0.1 0.032 14.3 0.1 2.1 1 0 0 1 1 1 1 Vibrio chemotaxis protein N terminus Peptidase_M16_C PF05193.16 EIE77107.1 - 1.9e-34 118.9 0.0 3.2e-34 118.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EIE77107.1 - 1.5e-31 109.1 1.4 1.5e-31 109.1 1.0 2.1 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) GAS PF13851.1 EIE77107.1 - 0.0026 16.9 0.4 0.0046 16.1 0.3 1.3 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Striatin PF08232.7 EIE77107.1 - 0.0064 16.8 0.2 0.066 13.5 0.0 2.4 2 0 0 2 2 2 1 Striatin family DUF507 PF04368.8 EIE77108.1 - 0.47 10.0 6.5 0.18 11.4 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF507) Clathrin_lg_ch PF01086.12 EIE77110.1 - 4.6e-43 147.7 9.9 5.1e-43 147.5 6.8 1.0 1 0 0 1 1 1 1 Clathrin light chain STAT1_TAZ2bind PF12162.3 EIE77110.1 - 0.023 14.0 0.1 0.052 12.9 0.1 1.6 1 0 0 1 1 1 0 STAT1 TAZ2 binding domain rve_3 PF13683.1 EIE77110.1 - 0.062 12.8 0.2 0.14 11.6 0.1 1.6 1 0 0 1 1 1 0 Integrase core domain DUF4200 PF13863.1 EIE77110.1 - 0.14 12.0 11.9 0.22 11.4 8.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DUF4407 PF14362.1 EIE77110.1 - 0.48 9.3 4.5 0.65 8.9 3.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Utp12 PF04003.7 EIE77111.1 - 1.1e-12 47.8 0.2 1.6e-12 47.2 0.1 1.2 1 0 0 1 1 1 1 Dip2/Utp12 Family Mg_trans_NIPA PF05653.9 EIE77113.1 - 4.2e-70 236.0 26.9 2.4e-58 197.4 13.3 2.0 1 1 1 2 2 2 2 Magnesium transporter NIPA PgpA PF04608.8 EIE77113.1 - 0.12 12.1 5.1 1.7 8.4 0.0 2.6 2 1 0 3 3 3 0 Phosphatidylglycerophosphatase A PDR_CDR PF06422.7 EIE77113.1 - 4.9 6.8 8.6 6.6 6.4 0.0 3.6 2 1 2 4 4 4 0 CDR ABC transporter ABC2_membrane_5 PF13346.1 EIE77113.1 - 5.7 6.1 33.2 2.3 7.4 2.0 3.1 3 0 0 3 3 3 0 ABC-2 family transporter protein SLS PF14611.1 EIE77114.1 - 2e-15 56.7 3.8 4.6e-15 55.6 2.6 1.6 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator KH_1 PF00013.24 EIE77114.1 - 9.1e-08 31.6 0.2 2.6e-06 26.9 0.8 2.4 2 0 0 2 2 2 1 KH domain KH_3 PF13014.1 EIE77114.1 - 0.00014 21.3 0.5 0.00058 19.4 0.3 2.1 1 0 0 1 1 1 1 KH domain NST1 PF13945.1 EIE77115.1 - 1.1e-59 201.6 21.6 1.1e-59 201.6 14.9 4.0 2 1 1 3 3 3 1 Salt tolerance down-regulator TFIIA PF03153.8 EIE77115.1 - 0.0025 17.8 25.1 0.0025 17.8 17.4 3.5 2 1 1 3 3 3 1 Transcription factor IIA, alpha/beta subunit CUE PF02845.11 EIE77116.1 - 6e-09 35.2 0.0 1.3e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 CUE domain GLTP PF08718.6 EIE77117.1 - 1.9e-27 96.1 0.1 1.2e-26 93.5 0.1 2.0 1 1 0 1 1 1 1 Glycolipid transfer protein (GLTP) DUF2838 PF10998.3 EIE77118.1 - 2.7e-36 123.8 5.8 2.7e-36 123.8 4.0 3.0 2 1 0 2 2 2 1 Protein of unknown function (DUF2838) Prominin PF05478.6 EIE77118.1 - 0.11 9.9 0.3 0.16 9.4 0.2 1.1 1 0 0 1 1 1 0 Prominin DUF16 PF01519.11 EIE77118.1 - 0.15 12.3 2.0 0.26 11.5 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF16 DUF4456 PF14644.1 EIE77119.1 - 0.072 12.3 2.2 0.09 11.9 1.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4456) DUF716 PF04819.7 EIE77120.1 - 0.02 14.2 0.2 0.021 14.2 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF716) DUF912 PF06024.7 EIE77120.1 - 0.14 12.2 2.0 0.16 12.0 1.4 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) THUMP PF02926.12 EIE77121.1 - 7e-15 55.1 3.6 2.7e-13 50.0 0.1 2.2 1 1 0 2 2 2 2 THUMP domain zf-C2H2 PF00096.21 EIE77122.1 - 2.9e-08 33.5 8.1 7.7e-05 22.7 0.3 3.5 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIE77122.1 - 5.2e-06 26.4 0.1 5.2e-06 26.4 0.1 4.7 5 0 0 5 5 5 2 Zinc-finger double domain zf-met PF12874.2 EIE77122.1 - 0.00017 21.6 1.8 0.0042 17.2 0.1 2.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EIE77122.1 - 0.0018 18.3 1.8 0.12 12.5 0.3 2.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 EIE77122.1 - 0.0018 18.4 7.3 0.025 14.8 0.2 3.5 4 0 0 4 4 4 2 C2H2-type zinc finger zf-Di19 PF05605.7 EIE77122.1 - 0.0061 16.6 0.7 0.02 15.0 0.5 1.9 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding TF_Zn_Ribbon PF08271.7 EIE77122.1 - 0.049 12.9 0.2 0.12 11.7 0.1 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding DUF1059 PF06348.6 EIE77122.1 - 0.06 13.1 0.3 0.06 13.1 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1059) zf-C2HC_2 PF13913.1 EIE77122.1 - 0.27 10.9 3.1 7.5 6.3 0.7 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type SH3_1 PF00018.23 EIE77123.1 - 2e-07 30.2 0.0 5.7e-07 28.8 0.0 1.9 1 0 0 1 1 1 1 SH3 domain RA PF00788.18 EIE77123.1 - 4.5e-06 27.0 1.5 0.0079 16.6 0.0 4.1 4 0 0 4 4 4 2 Ras association (RalGDS/AF-6) domain SH3_9 PF14604.1 EIE77123.1 - 2.1e-05 23.9 0.0 6.6e-05 22.4 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain DUF1694 PF07997.6 EIE77124.1 - 0.27 11.1 1.7 0.53 10.2 0.7 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1694) TPR_11 PF13414.1 EIE77126.1 - 3.7e-12 45.7 0.2 7.2e-12 44.7 0.1 1.5 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.12 EIE77126.1 - 3e-11 42.3 0.4 9.4e-05 22.0 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 EIE77126.1 - 7.3e-11 42.2 0.5 1.3e-10 41.4 0.3 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 EIE77126.1 - 3.3e-10 39.1 0.3 0.00018 21.0 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 EIE77126.1 - 2.9e-08 34.1 0.1 8.8e-08 32.6 0.0 1.9 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 EIE77126.1 - 1.6e-06 28.1 0.3 0.042 14.4 0.1 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 EIE77126.1 - 0.00025 20.5 0.2 0.21 11.4 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 EIE77126.1 - 0.00036 20.1 0.1 1.6 8.6 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 EIE77126.1 - 0.00036 20.3 0.1 0.0009 19.0 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.1 EIE77126.1 - 0.00075 19.3 0.3 0.0016 18.3 0.2 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat Apc3 PF12895.2 EIE77126.1 - 0.0013 18.8 0.1 0.003 17.6 0.0 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.13 EIE77126.1 - 0.0087 15.9 0.6 2.1 8.2 0.0 2.6 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain HPD PF05044.7 EIE77126.1 - 0.015 15.0 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 Homeo-prospero domain Fis1_TPR_C PF14853.1 EIE77126.1 - 0.03 14.2 0.1 0.087 12.7 0.0 1.8 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_17 PF13431.1 EIE77126.1 - 0.06 13.5 0.1 0.23 11.7 0.0 2.1 2 0 0 2 2 1 0 Tetratricopeptide repeat DDE_3 PF13358.1 EIE77128.1 - 0.001 18.8 0.0 0.0015 18.3 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease LrgB PF04172.11 EIE77130.1 - 2.8e-27 95.3 17.9 2.8e-27 95.2 9.4 2.7 2 1 0 2 2 2 1 LrgB-like family LrgA PF03788.9 EIE77130.1 - 1.1e-08 34.5 1.7 1.1e-08 34.5 1.2 3.0 3 0 0 3 3 3 1 LrgA family Sec39 PF08314.6 EIE77131.1 - 1.1e-62 212.1 5.3 1.7e-62 211.4 3.7 1.3 1 0 0 1 1 1 1 Secretory pathway protein Sec39 PA PF02225.17 EIE77133.1 - 0.011 15.4 0.0 0.018 14.7 0.0 1.3 1 0 0 1 1 1 0 PA domain YajC PF02699.10 EIE77133.1 - 0.17 11.5 0.3 0.3 10.8 0.2 1.4 1 0 0 1 1 1 0 Preprotein translocase subunit DUF726 PF05277.7 EIE77134.1 - 2e-39 135.4 14.7 1e-26 93.6 0.1 3.7 2 1 2 4 4 4 3 Protein of unknown function (DUF726) TauE PF01925.14 EIE77134.1 - 0.00023 20.7 1.6 0.00034 20.1 1.1 1.2 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE MutS_IV PF05190.13 EIE77135.1 - 0.00017 21.7 0.0 0.0004 20.4 0.0 1.6 1 1 0 1 1 1 1 MutS family domain IV Viral_env_E26 PF11050.3 EIE77136.1 - 0.11 11.7 0.3 0.11 11.6 0.2 1.1 1 0 0 1 1 1 0 Virus envelope protein E26 Methyltransf_33 PF10017.4 EIE77137.1 - 2.7e-32 111.3 0.0 6.8e-32 110.0 0.0 1.8 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.11 EIE77137.1 - 4.7e-24 85.1 2.9 5.2e-12 45.6 0.2 2.3 1 1 1 2 2 2 2 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.2 EIE77137.1 - 6.4e-09 36.2 2.0 2.7e-08 34.2 0.6 2.2 1 1 1 2 2 2 1 DinB superfamily DDE_3 PF13358.1 EIE77138.1 - 1.9e-30 105.5 0.0 3.9e-30 104.5 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 EIE77138.1 - 3.3e-08 33.6 0.0 7.5e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.1 EIE77138.1 - 5.6e-07 29.4 0.0 1.5e-05 24.8 0.0 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.1 EIE77138.1 - 6e-07 28.9 1.7 4.3e-05 23.0 0.0 2.7 3 0 0 3 3 3 1 Homeodomain-like domain HTH_32 PF13565.1 EIE77138.1 - 7.8e-06 26.5 0.1 3e-05 24.7 0.0 2.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_17 PF12728.2 EIE77138.1 - 5.9e-05 23.2 0.0 0.0087 16.2 0.0 2.8 2 0 0 2 2 2 1 Helix-turn-helix domain DDE_1 PF03184.14 EIE77138.1 - 0.0034 16.5 0.2 0.02 14.0 0.1 2.2 2 1 0 2 2 2 1 DDE superfamily endonuclease rve PF00665.21 EIE77138.1 - 0.02 15.0 0.1 0.1 12.7 0.0 2.2 3 0 0 3 3 3 0 Integrase core domain LZ_Tnp_IS481 PF13011.1 EIE77138.1 - 0.069 13.4 0.0 0.22 11.9 0.0 1.8 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 HTH_Tnp_1 PF01527.15 EIE77138.1 - 0.14 12.0 0.2 0.75 9.7 0.1 2.1 1 1 0 2 2 2 0 Transposase DDE_1 PF03184.14 EIE77140.1 - 0.04 13.0 0.1 0.17 11.0 0.2 1.9 2 0 0 2 2 2 0 DDE superfamily endonuclease Myc_N PF01056.13 EIE77140.1 - 0.32 10.1 3.4 0.41 9.7 2.4 1.1 1 0 0 1 1 1 0 Myc amino-terminal region adh_short_C2 PF13561.1 EIE77142.1 - 1.7e-31 109.8 0.3 2.1e-31 109.5 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EIE77142.1 - 1.2e-29 103.3 0.5 1.5e-29 103.0 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIE77142.1 - 1.1e-12 48.0 0.1 1.5e-12 47.5 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EIE77142.1 - 0.004 16.6 0.1 0.0053 16.2 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIE77142.1 - 0.0096 15.9 0.1 0.026 14.5 0.1 1.6 1 1 0 1 1 1 1 NADH(P)-binding 3HCDH_N PF02737.13 EIE77142.1 - 0.059 13.0 0.5 0.1 12.2 0.1 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 EIE77142.1 - 0.082 11.9 0.1 0.16 11.0 0.1 1.5 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF2824 PF11039.3 EIE77142.1 - 0.12 12.1 0.6 0.22 11.2 0.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2824) Sel1 PF08238.7 EIE77143.1 - 3.4e-29 100.6 1.3 3.5e-07 30.6 0.0 7.1 7 0 0 7 7 7 5 Sel1 repeat Peptidase_C11 PF03415.9 EIE77143.1 - 0.027 13.4 0.1 0.031 13.2 0.0 1.2 1 0 0 1 1 1 0 Clostripain family DUF3391 PF11871.3 EIE77143.1 - 0.031 14.5 2.4 0.081 13.1 1.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) ATP-synt_J PF04911.7 EIE77145.1 - 3.6e-20 71.1 0.4 4e-20 71.0 0.2 1.0 1 0 0 1 1 1 1 ATP synthase j chain La PF05383.12 EIE77146.1 - 2.7e-20 71.9 0.2 6.1e-20 70.7 0.1 1.7 1 0 0 1 1 1 1 La domain Scm3 PF10384.4 EIE77146.1 - 0.47 9.9 4.4 0.79 9.2 1.8 2.3 2 0 0 2 2 2 0 Centromere protein Scm3 Mito_carr PF00153.22 EIE77147.1 - 1.6e-66 220.0 0.4 1.2e-21 76.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein bZIP_1 PF00170.16 EIE77148.1 - 3.5e-12 46.0 13.8 1.6e-11 44.0 9.6 2.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EIE77148.1 - 3.7e-08 33.0 13.7 3.7e-08 33.0 9.5 3.1 4 0 0 4 4 4 1 Basic region leucine zipper EcoEI_R_C PF08463.5 EIE77148.1 - 0.00057 19.7 2.2 0.00057 19.7 1.5 2.1 2 0 0 2 2 2 1 EcoEI R protein C-terminal DUF3436 PF11918.3 EIE77148.1 - 0.037 14.2 0.9 0.088 13.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3436) NusB PF01029.13 EIE77148.1 - 9.8 6.1 10.0 0.9 9.5 1.9 2.5 2 0 0 2 2 2 0 NusB family DnaJ PF00226.26 EIE77149.1 - 2.4e-16 59.1 0.8 5.3e-16 58.0 0.6 1.6 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.1 EIE77149.1 - 0.0076 15.6 0.0 0.039 13.3 0.0 2.1 2 0 0 2 2 2 1 A repeated domain in UCH-protein TPR_2 PF07719.12 EIE77149.1 - 0.0083 15.9 0.0 0.062 13.2 0.0 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat DUF1771 PF08590.5 EIE77149.1 - 0.042 13.8 0.1 0.094 12.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1771) Peptidase_A6 PF01829.11 EIE77149.1 - 0.13 11.2 0.1 0.19 10.7 0.1 1.2 1 0 0 1 1 1 0 Peptidase A6 family Amidase_2 PF01510.20 EIE77149.1 - 0.14 12.2 0.0 0.17 11.9 0.0 1.3 1 1 0 1 1 1 0 N-acetylmuramoyl-L-alanine amidase CNH PF00780.17 EIE77151.1 - 3.6e-07 29.8 0.0 5.7e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 CNH domain Clathrin PF00637.15 EIE77152.1 - 1.1e-05 25.1 0.1 0.0096 15.5 0.0 2.4 2 0 0 2 2 2 2 Region in Clathrin and VPS Trehalase PF01204.13 EIE77153.1 - 1.5e-103 347.1 20.6 5e-64 216.8 7.4 3.0 1 1 2 3 3 3 3 Trehalase DUF2414 PF10309.4 EIE77153.1 - 0.023 14.3 1.4 1.6 8.4 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2414) Fibrillarin PF01269.12 EIE77154.1 - 2.2e-111 370.2 0.1 2.7e-111 370.0 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 EIE77154.1 - 2.6e-05 23.8 0.0 3.9e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.1 EIE77154.1 - 0.00033 20.2 0.0 0.00047 19.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EIE77154.1 - 0.025 14.1 0.0 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF1977 PF09320.6 EIE77155.1 - 2.2e-22 79.2 2.3 3.7e-22 78.6 1.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.26 EIE77155.1 - 7.5e-15 54.4 0.3 3.8e-14 52.1 0.2 2.0 1 1 0 1 1 1 1 DnaJ domain BTB_2 PF02214.17 EIE77156.1 - 5e-07 29.8 0.6 1.4e-05 25.2 0.1 2.4 1 1 1 2 2 2 1 BTB/POZ domain Ribosomal_S6e PF01092.14 EIE77157.1 - 5.2e-48 161.8 0.3 5.2e-48 161.8 0.2 2.0 2 0 0 2 2 2 1 Ribosomal protein S6e EF-1_beta_acid PF10587.4 EIE77157.1 - 9.9 6.4 9.4 23 5.2 6.5 1.6 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region SH3_2 PF07653.12 EIE77158.1 - 2.5e-09 36.4 0.0 3e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EIE77158.1 - 7.8e-09 34.9 0.2 1e-08 34.6 0.1 1.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EIE77158.1 - 6.3e-08 31.8 0.1 8.3e-08 31.4 0.0 1.2 1 0 0 1 1 1 1 SH3 domain Homeobox PF00046.24 EIE77159.1 - 3e-16 58.7 0.7 4.9e-16 58.0 0.5 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EIE77159.1 - 0.032 13.9 0.0 0.076 12.7 0.0 1.6 1 0 0 1 1 1 0 Homeobox KN domain HSP70 PF00012.15 EIE77160.1 - 4.2e-242 804.3 12.8 4.9e-242 804.1 8.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EIE77160.1 - 4.3e-18 64.9 2.0 5.8e-17 61.2 1.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 EIE77160.1 - 0.00091 18.8 0.0 0.0026 17.3 0.0 1.8 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Asp_decarbox PF02261.11 EIE77160.1 - 0.023 14.2 0.1 0.086 12.4 0.0 2.0 2 0 0 2 2 2 0 Aspartate decarboxylase FtsA PF14450.1 EIE77160.1 - 0.051 13.4 7.6 0.56 10.0 0.0 3.8 3 3 0 3 3 3 0 Cell division protein FtsA DDR PF08841.5 EIE77160.1 - 0.12 11.2 5.0 0.1 11.4 0.4 2.5 3 0 0 3 3 3 0 Diol dehydratase reactivase ATPase-like domain eIF3_N PF09440.5 EIE77160.1 - 0.12 12.5 5.3 0.083 13.0 2.3 1.8 2 0 0 2 2 2 0 eIF3 subunit 6 N terminal domain FAA_hydrolase PF01557.13 EIE77161.1 - 4.4e-46 157.0 0.0 5.1e-46 156.8 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF953 PF06110.6 EIE77161.1 - 0.11 11.9 0.0 0.33 10.4 0.0 1.7 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF953) HATPase_c PF02518.21 EIE77162.1 - 6.8e-30 103.0 0.0 1.1e-29 102.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EIE77162.1 - 9.8e-17 60.7 3.0 1.5e-16 60.1 1.5 1.8 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.19 EIE77162.1 - 2.5e-07 30.6 0.0 5.5e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c_3 PF13589.1 EIE77162.1 - 0.0053 16.4 0.0 0.015 14.9 0.0 1.7 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase A_deamin PF02137.13 EIE77163.1 - 1.6e-18 67.1 0.9 3.6e-17 62.7 0.0 2.1 1 1 1 2 2 2 2 Adenosine-deaminase (editase) domain Septin PF00735.13 EIE77164.1 - 3.3e-51 173.9 0.1 6.1e-51 173.0 0.0 1.4 1 0 0 1 1 1 1 Septin BMP2K_C PF15282.1 EIE77164.1 - 0.026 14.7 0.3 0.03 14.4 0.2 1.3 1 0 0 1 1 1 0 BMP-2-inducible protein kinase C-terminus MCRS_N PF13325.1 EIE77164.1 - 0.042 13.3 8.0 0.071 12.6 5.5 1.4 1 0 0 1 1 1 0 N-terminal region of micro-spherule protein Colicin-DNase PF12639.2 EIE77164.1 - 0.051 13.8 2.0 0.094 12.9 1.4 1.5 1 0 0 1 1 1 0 DNase/tRNase domain of colicin-like bacteriocin DUF763 PF05559.6 EIE77164.1 - 0.088 11.7 1.0 0.12 11.3 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF763) Cep57_CLD_2 PF14197.1 EIE77164.1 - 0.64 9.9 6.4 1.3 8.9 4.4 1.5 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 Exonuc_VII_L PF02601.10 EIE77164.1 - 1 8.5 8.5 1.6 7.8 5.9 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit RhoGEF PF00621.15 EIE77169.1 - 7.7e-40 136.6 2.8 1.2e-39 136.0 1.9 1.3 1 0 0 1 1 1 1 RhoGEF domain PH_10 PF15411.1 EIE77169.1 - 2.3e-26 92.2 0.4 4.9e-26 91.1 0.3 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain SHR3_chaperone PF08229.6 EIE77170.1 - 0.087 11.7 0.5 0.15 11.0 0.3 1.3 1 0 0 1 1 1 0 ER membrane protein SH3 LRR_8 PF13855.1 EIE77170.1 - 0.77 9.5 4.3 3.6 7.4 2.0 3.0 2 1 0 2 2 2 0 Leucine rich repeat LRR_7 PF13504.1 EIE77170.1 - 0.97 9.9 5.9 71 4.2 0.0 5.7 5 1 1 6 6 6 0 Leucine rich repeat LRR_4 PF12799.2 EIE77170.1 - 6.1 6.5 10.5 1.4 8.6 0.6 4.5 6 1 0 6 6 6 0 Leucine Rich repeats (2 copies) MKT1_C PF12246.3 EIE77171.1 - 1.1e-57 194.8 0.6 1.6e-57 194.2 0.4 1.2 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.3 EIE77171.1 - 3.9e-30 104.0 0.2 1.1e-29 102.5 0.1 1.9 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_I PF00867.13 EIE77171.1 - 4.8e-13 48.9 0.0 1.1e-12 47.7 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EIE77171.1 - 2.9e-06 27.4 0.0 1e-05 25.7 0.0 2.0 1 0 0 1 1 1 1 XPG N-terminal domain Ribosomal_S17 PF00366.15 EIE77173.1 - 7.1e-30 102.8 2.0 1.1e-29 102.2 1.4 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 CDC48_2 PF02933.12 EIE77173.1 - 0.0021 17.6 0.3 0.0049 16.4 0.0 1.7 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 GAS2 PF02187.12 EIE77174.1 - 5e-08 32.6 0.1 1.5e-07 31.0 0.1 1.8 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Spectrin PF00435.16 EIE77174.1 - 0.008 16.4 0.9 0.008 16.4 0.7 16.2 14 4 2 16 16 16 6 Spectrin repeat Aldedh PF00171.17 EIE77176.1 - 1.6e-92 310.2 0.0 2.1e-92 309.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Arginase PF00491.16 EIE77177.1 - 8.2e-77 258.2 0.1 9.5e-77 257.9 0.0 1.0 1 0 0 1 1 1 1 Arginase family DUF1057 PF06342.7 EIE77177.1 - 0.1 11.3 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) DUF1759 PF03564.10 EIE77178.1 - 7.3e-06 25.8 0.2 9.8e-06 25.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) AP_endonuc_2 PF01261.19 EIE77178.1 - 0.069 12.4 0.0 0.096 11.9 0.0 1.2 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel DUF1759 PF03564.10 EIE77181.1 - 7.3e-06 25.8 0.2 9.8e-06 25.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) AP_endonuc_2 PF01261.19 EIE77181.1 - 0.069 12.4 0.0 0.096 11.9 0.0 1.2 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel MGC-24 PF05283.6 EIE77183.1 - 0.48 10.1 15.8 0.69 9.6 11.0 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) Glutaredoxin PF00462.19 EIE77184.1 - 9.8e-08 31.8 0.5 9.2e-07 28.7 0.4 2.1 1 1 0 1 1 1 1 Glutaredoxin TSCPD PF12637.2 EIE77184.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.4 1 1 0 1 1 1 0 TSCPD domain Semialdhyde_dhC PF02774.13 EIE77185.1 - 7e-43 146.6 0.0 9.5e-43 146.1 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 EIE77185.1 - 3.4e-32 111.2 0.0 5.7e-32 110.5 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Gp_dh_C PF02800.15 EIE77185.1 - 0.011 15.2 0.1 0.026 13.9 0.0 1.6 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain DXP_reductoisom PF02670.11 EIE77185.1 - 0.015 15.8 0.0 0.048 14.1 0.0 1.9 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase GFO_IDH_MocA PF01408.17 EIE77185.1 - 0.028 14.9 0.1 0.2 12.2 0.0 2.1 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold DapB_N PF01113.15 EIE77185.1 - 0.033 14.1 0.0 0.063 13.1 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_10 PF13460.1 EIE77185.1 - 0.038 14.0 0.1 0.063 13.2 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding Ribosomal_S24e PF01282.14 EIE77186.1 - 1.1e-35 121.3 0.5 1.6e-35 120.7 0.1 1.4 1 1 1 2 2 2 1 Ribosomal protein S24e Ribosomal_S2 PF00318.15 EIE77186.1 - 0.11 11.6 0.5 0.14 11.4 0.3 1.1 1 0 0 1 1 1 0 Ribosomal protein S2 LETM1 PF07766.8 EIE77187.1 - 5.3e-101 337.1 1.1 5.3e-101 337.1 0.8 2.4 2 1 1 3 3 3 1 LETM1-like protein SAP PF02037.22 EIE77187.1 - 0.002 17.5 0.0 0.19 11.2 0.0 3.0 2 0 0 2 2 2 1 SAP domain AKNA PF12443.3 EIE77187.1 - 0.35 10.8 14.7 0.35 10.9 7.0 2.4 1 1 1 2 2 2 0 AT-hook-containing transcription factor SPX PF03105.14 EIE77187.1 - 1.4 8.5 14.3 2.7 7.7 9.9 1.4 1 0 0 1 1 1 0 SPX domain TMEM51 PF15345.1 EIE77187.1 - 3 7.4 8.7 7.6 6.1 6.0 1.6 1 0 0 1 1 1 0 Transmembrane protein 51 Sigma_reg_N PF13800.1 EIE77188.1 - 5.5 7.0 7.6 8.8 6.4 0.8 2.5 1 1 1 2 2 2 0 Sigma factor regulator N-terminal Septin PF00735.13 EIE77189.1 - 3.6e-114 380.5 0.7 4.5e-114 380.2 0.5 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EIE77189.1 - 3.3e-08 33.4 0.0 6.3e-08 32.5 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EIE77189.1 - 6.4e-08 31.9 0.1 1.1e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 EIE77189.1 - 1.1e-06 27.9 0.0 1.9e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.22 EIE77189.1 - 1.3e-05 24.7 0.5 0.00018 20.9 0.1 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EIE77189.1 - 3.7e-05 23.6 1.4 0.038 13.8 0.3 2.4 1 1 1 2 2 2 2 Dynamin family ABC_tran PF00005.22 EIE77189.1 - 0.00015 22.0 0.0 0.00031 21.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_10 PF12846.2 EIE77189.1 - 0.0003 20.3 0.0 0.00048 19.6 0.0 1.4 1 0 0 1 1 1 1 AAA-like domain Gtr1_RagA PF04670.7 EIE77189.1 - 0.00056 19.1 0.1 0.0026 16.9 0.0 1.9 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region NB-ARC PF00931.17 EIE77189.1 - 0.00064 18.6 0.1 0.0011 17.8 0.1 1.4 1 0 0 1 1 1 1 NB-ARC domain Miro PF08477.8 EIE77189.1 - 0.002 18.6 0.0 0.0043 17.5 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 EIE77189.1 - 0.002 17.5 0.2 0.0068 15.7 0.1 1.9 2 1 0 2 2 2 1 Ras family AAA_22 PF13401.1 EIE77189.1 - 0.0024 18.0 0.0 0.0049 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EIE77189.1 - 0.0028 17.6 0.0 0.0053 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain FtsK_SpoIIIE PF01580.13 EIE77189.1 - 0.003 17.0 0.0 0.006 16.0 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_29 PF13555.1 EIE77189.1 - 0.011 15.2 0.0 0.023 14.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.1 EIE77189.1 - 0.012 16.3 0.7 0.84 10.4 0.1 2.6 1 1 1 2 2 2 0 AAA domain AAA_14 PF13173.1 EIE77189.1 - 0.022 14.6 0.0 0.066 13.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain Guanylate_kin PF00625.16 EIE77189.1 - 0.025 14.0 0.6 0.11 11.9 0.1 2.2 2 0 0 2 2 2 0 Guanylate kinase T2SE PF00437.15 EIE77189.1 - 0.037 12.9 1.0 0.056 12.3 0.1 1.7 2 1 1 3 3 3 0 Type II/IV secretion system protein DUF815 PF05673.8 EIE77189.1 - 0.04 12.8 0.0 0.076 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) IIGP PF05049.8 EIE77189.1 - 0.04 12.7 0.3 0.084 11.6 0.1 1.6 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) Sigma54_activat PF00158.21 EIE77189.1 - 0.05 13.0 0.0 0.089 12.2 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF3585 PF12130.3 EIE77189.1 - 0.064 13.1 0.2 0.31 10.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3585) AAA_24 PF13479.1 EIE77189.1 - 0.074 12.6 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 EIE77189.1 - 0.09 12.4 0.4 0.28 10.8 0.1 2.0 1 1 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EIE77189.1 - 0.13 12.1 0.2 0.38 10.6 0.1 1.9 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EIE77189.1 - 0.14 12.3 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase zf-H2C2_2 PF13465.1 EIE77190.1 - 2.2e-23 81.3 30.9 1.6e-08 34.4 0.9 5.6 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2 PF00096.21 EIE77190.1 - 6.3e-20 70.2 34.4 5.3e-06 26.4 0.3 5.0 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIE77190.1 - 4.9e-13 48.4 23.7 0.0037 17.4 0.1 5.2 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EIE77190.1 - 0.00015 21.7 9.4 0.99 9.6 0.4 4.5 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EIE77190.1 - 0.002 17.9 13.4 0.16 11.8 0.2 4.5 4 0 0 4 4 4 3 C2H2-type zinc finger zf-met PF12874.2 EIE77190.1 - 0.013 15.6 7.3 4 7.7 0.4 4.4 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-TRAF PF02176.13 EIE77190.1 - 0.74 10.2 19.7 0.88 9.9 2.5 3.8 2 1 2 4 4 4 0 TRAF-type zinc finger zf-CGNR PF11706.3 EIE77190.1 - 2.3 7.7 9.3 0.24 10.9 0.3 3.1 4 0 0 4 4 4 0 CGNR zinc finger LUC7 PF03194.10 EIE77192.1 - 1e-57 195.5 14.9 1.5e-57 195.0 10.3 1.2 1 0 0 1 1 1 1 LUC7 N_terminus AAA_13 PF13166.1 EIE77192.1 - 4.8e-05 22.0 7.7 6e-05 21.7 5.3 1.1 1 0 0 1 1 1 1 AAA domain IncA PF04156.9 EIE77192.1 - 0.0049 16.4 10.6 0.0049 16.4 7.3 2.1 2 0 0 2 2 2 1 IncA protein DUF4175 PF13779.1 EIE77192.1 - 0.99 7.0 19.1 1.5 6.4 13.2 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4175) OrfB_Zn_ribbon PF07282.6 EIE77193.1 - 0.11 12.1 0.7 0.2 11.3 0.5 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Kazal_1 PF00050.16 EIE77193.1 - 0.46 10.5 3.0 0.42 10.6 0.4 2.0 2 0 0 2 2 2 0 Kazal-type serine protease inhibitor domain ATP-synt_ab PF00006.20 EIE77194.1 - 6.2e-114 378.8 0.0 9.6e-114 378.2 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EIE77194.1 - 7.8e-25 87.5 0.1 1.2e-24 86.8 0.1 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EIE77194.1 - 1.1e-12 47.9 1.7 1.1e-12 47.9 1.2 2.6 3 0 0 3 3 3 1 ATP synthase alpha/beta family, beta-barrel domain AAA_14 PF13173.1 EIE77194.1 - 0.12 12.2 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain SNF2_N PF00176.18 EIE77195.1 - 1.9e-50 171.3 0.8 2.3e-30 105.4 0.0 3.2 2 1 1 3 3 3 2 SNF2 family N-terminal domain Chromo PF00385.19 EIE77195.1 - 2.1e-15 56.1 18.8 5.6e-12 45.1 0.6 3.8 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 EIE77195.1 - 1.8e-14 53.3 0.1 9.4e-14 51.0 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RhoGEF PF00621.15 EIE77197.1 - 5.3e-19 68.7 3.0 1e-18 67.8 2.1 1.5 1 0 0 1 1 1 1 RhoGEF domain NIR_SIR PF01077.17 EIE77198.1 - 6.3e-50 168.6 0.1 1.7e-43 147.6 0.1 2.5 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain Flavodoxin_1 PF00258.20 EIE77198.1 - 3.3e-31 108.1 0.2 1.1e-30 106.5 0.0 2.1 2 0 0 2 2 2 1 Flavodoxin NIR_SIR_ferr PF03460.12 EIE77198.1 - 3.5e-27 93.8 0.0 5.9e-14 51.4 0.0 2.7 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain POR_N PF01855.14 EIE77198.1 - 2.8e-16 59.7 4.8 3.1e-16 59.6 1.7 2.2 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Pkinase PF00069.20 EIE77199.1 - 3.1e-70 236.3 0.0 5e-70 235.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE77199.1 - 2.8e-38 131.5 0.0 5.5e-38 130.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE77199.1 - 1.5e-08 34.0 0.0 2.4e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EIE77199.1 - 0.00045 19.6 0.4 0.00093 18.5 0.3 1.5 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 EIE77199.1 - 0.0065 15.5 0.2 0.015 14.3 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIE77199.1 - 0.0076 16.0 0.0 0.051 13.3 0.1 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family DUF3446 PF11928.3 EIE77199.1 - 2.6 8.2 7.1 0.36 11.0 0.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) DDHD PF02862.12 EIE77201.1 - 4.8e-20 72.3 11.7 3.6e-17 62.9 8.1 2.9 1 1 0 1 1 1 1 DDHD domain WD40 PF00400.27 EIE77202.1 - 1.6e-21 75.3 7.7 6.8e-07 28.9 0.0 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat Sec16_C PF12931.2 EIE77202.1 - 1.4e-09 38.1 0.2 8.8e-09 35.5 0.1 2.3 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 DivIC PF04977.10 EIE77205.1 - 0.01 15.2 9.0 0.029 13.8 6.3 1.7 1 0 0 1 1 1 0 Septum formation initiator FbpA PF05833.6 EIE77205.1 - 0.16 10.4 11.7 0.35 9.3 3.9 2.1 2 0 0 2 2 2 0 Fibronectin-binding protein A N-terminus (FbpA) Mnd1 PF03962.10 EIE77205.1 - 0.42 10.2 10.2 0.12 11.9 4.7 1.8 2 0 0 2 2 2 0 Mnd1 family Activator_LAG-3 PF11498.3 EIE77205.1 - 0.99 8.0 23.9 1.6 7.3 16.6 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Epimerase PF01370.16 EIE77207.1 - 4.1e-54 183.5 0.0 5e-54 183.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EIE77207.1 - 4.4e-19 68.2 0.0 9.7e-18 63.8 0.0 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EIE77207.1 - 7.6e-16 57.8 0.0 4.7e-15 55.2 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EIE77207.1 - 1.7e-12 46.8 0.0 2.4e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 EIE77207.1 - 9.5e-11 41.8 0.0 1.5e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 EIE77207.1 - 2.8e-10 39.5 0.0 9.3e-10 37.8 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EIE77207.1 - 2e-08 34.4 0.0 3.8e-08 33.5 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EIE77207.1 - 7e-07 29.0 0.0 1.3e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 EIE77207.1 - 1.4e-05 24.4 0.0 0.00012 21.3 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family TrkA_N PF02254.13 EIE77207.1 - 0.0067 16.4 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain UDPG_MGDP_dh_N PF03721.9 EIE77207.1 - 0.036 13.4 0.0 0.062 12.6 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pkinase PF00069.20 EIE77208.1 - 4.9e-34 117.6 0.1 9.4e-34 116.7 0.1 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE77208.1 - 3.4e-13 49.2 0.1 2.1e-12 46.6 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EIE77208.1 - 0.0044 16.7 0.0 0.038 13.7 0.0 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EIE77208.1 - 0.0045 16.3 0.9 0.013 14.8 0.0 2.0 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL VPS11_C PF12451.3 EIE77208.1 - 0.7 9.7 3.2 1.5 8.7 2.2 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting protein 11 C terminal PIG-Y PF15159.1 EIE77209.1 - 2.8e-21 75.4 6.0 3.9e-21 75.0 4.2 1.2 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y PIG-P PF08510.7 EIE77209.1 - 0.72 9.4 8.1 1 8.9 5.6 1.2 1 0 0 1 1 1 0 PIG-P tRNA_bind PF01588.15 EIE77210.1 - 5.9e-28 96.5 0.0 1.2e-27 95.5 0.0 1.6 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C_3 PF14497.1 EIE77210.1 - 9e-11 42.1 0.7 2e-10 41.0 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EIE77210.1 - 6.5e-07 29.2 0.0 2.7e-06 27.2 0.0 2.1 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EIE77210.1 - 2.1e-05 24.2 0.0 3.9e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Rtf2 PF04641.7 EIE77210.1 - 0.00062 19.0 5.2 0.001 18.3 3.6 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger RNase_H2-Ydr279 PF09468.5 EIE77210.1 - 0.024 13.8 3.8 0.037 13.2 2.6 1.3 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) NPR3 PF03666.8 EIE77210.1 - 0.55 8.7 4.8 0.85 8.0 3.3 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 NARP1 PF12569.3 EIE77210.1 - 0.63 8.7 9.8 0.95 8.1 6.8 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RR_TM4-6 PF06459.7 EIE77210.1 - 5.5 6.8 9.8 8.6 6.1 6.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PUF PF00806.14 EIE77211.1 - 1.7e-66 216.0 14.4 1.8e-08 33.4 0.0 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Ras PF00071.17 EIE77212.1 - 4.8e-61 204.8 0.3 5.8e-61 204.6 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIE77212.1 - 9.6e-20 71.2 0.0 1.5e-19 70.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIE77212.1 - 1e-08 34.6 0.0 1.3e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EIE77212.1 - 1.5e-05 24.5 0.0 2.3e-05 23.9 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain TcdB_N PF12918.2 EIE77212.1 - 0.0026 17.7 0.7 0.012 15.6 0.1 2.1 2 0 0 2 2 2 1 TcdB toxin N-terminal helical domain FeoB_N PF02421.13 EIE77212.1 - 0.0071 15.6 0.1 0.021 14.0 0.1 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.18 EIE77212.1 - 0.012 15.5 0.0 0.02 14.8 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase CTP_transf_3 PF02348.14 EIE77212.1 - 0.034 13.7 0.3 0.35 10.4 0.1 2.0 2 0 0 2 2 2 0 Cytidylyltransferase Gtr1_RagA PF04670.7 EIE77212.1 - 0.074 12.1 0.1 0.1 11.7 0.1 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region 2Fe-2S_thioredx PF01257.14 EIE77212.1 - 0.08 12.5 0.1 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 Thioredoxin-like [2Fe-2S] ferredoxin RGS-like PF09128.6 EIE77212.1 - 0.094 12.1 0.3 0.16 11.4 0.2 1.3 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain DUF258 PF03193.11 EIE77212.1 - 0.12 11.5 0.6 0.22 10.6 0.1 1.9 2 1 0 2 2 2 0 Protein of unknown function, DUF258 Ras PF00071.17 EIE77213.1 - 1.5e-53 180.4 0.2 1.8e-53 180.2 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIE77213.1 - 5.8e-20 71.9 0.3 9.1e-20 71.3 0.1 1.4 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EIE77213.1 - 1.9e-08 33.7 0.1 2.3e-08 33.4 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EIE77213.1 - 1.3e-06 27.9 0.1 3.1e-06 26.7 0.0 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EIE77213.1 - 2.1e-05 24.4 0.1 3.5e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 EIE77213.1 - 0.0028 16.4 0.0 0.15 10.7 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit AAA_22 PF13401.1 EIE77213.1 - 0.21 11.7 1.1 24 5.0 0.1 2.7 1 1 2 3 3 3 0 AAA domain Pkinase PF00069.20 EIE77214.1 - 2.3e-33 115.4 1.6 3e-22 79.0 0.1 3.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIE77214.1 - 1.5e-12 47.1 0.6 1.1e-11 44.2 0.1 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase WD40 PF00400.27 EIE77215.1 - 0.00025 20.7 15.1 1.4 8.9 0.0 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat eIF2A PF08662.6 EIE77215.1 - 0.00038 20.2 1.2 0.011 15.4 0.4 2.4 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A KH_1 PF00013.24 EIE77216.1 - 0.0094 15.5 0.0 2.5 7.8 0.0 2.5 2 0 0 2 2 2 2 KH domain RasGEF PF00617.14 EIE77217.1 - 2.7e-44 151.1 0.1 5.6e-44 150.1 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain DUF3815 PF12821.2 EIE77217.1 - 0.13 12.2 0.1 0.25 11.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3815) GPI-anchored PF10342.4 EIE77218.1 - 1.5e-10 41.3 1.2 1e-09 38.7 0.8 2.5 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family HTH_Tnp_Tc3_2 PF01498.13 EIE77219.1 - 3.9e-16 58.8 0.9 1.2e-15 57.2 0.6 1.9 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.1 EIE77219.1 - 2.4e-10 40.3 0.2 5.6e-07 29.4 0.1 2.3 2 0 0 2 2 2 2 DDE superfamily endonuclease RVT_1 PF00078.22 EIE77220.1 - 3.8e-31 108.1 0.0 6.1e-31 107.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.1 EIE77220.1 - 0.00086 19.5 2.7 0.0019 18.4 1.9 1.6 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase DDE_3 PF13358.1 EIE77221.1 - 1.2e-17 64.0 0.0 2.6e-17 62.9 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE77221.1 - 5.7e-09 35.9 2.2 1.6e-08 34.4 0.4 2.5 1 1 1 2 2 2 1 Transposase NUDIX_4 PF14815.1 EIE77221.1 - 0.014 14.7 0.3 0.027 13.9 0.2 1.5 1 0 0 1 1 1 0 NUDIX domain HTH_23 PF13384.1 EIE77221.1 - 0.037 13.6 0.0 0.077 12.6 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain HTH_7 PF02796.10 EIE77221.1 - 0.053 13.3 0.1 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase GcrA PF07750.6 EIE77221.1 - 0.058 13.5 0.1 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 GcrA cell cycle regulator RVT_1 PF00078.22 EIE77222.1 - 1e-13 51.1 0.0 2.2e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Spuma_A9PTase PF03539.9 EIE77222.1 - 0.0038 17.1 0.3 0.016 15.1 0.0 1.9 1 1 1 2 2 2 1 Spumavirus aspartic protease (A9) rve PF00665.21 EIE77223.1 - 2.3e-24 85.8 0.0 6.4e-23 81.1 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 EIE77223.1 - 2.5e-15 56.4 0.1 4.5e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.5 EIE77223.1 - 0.0047 16.3 0.1 0.0096 15.3 0.0 1.6 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Asp_protease_2 PF13650.1 EIE77224.1 - 1.3e-06 28.7 0.0 4.1e-06 27.1 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.12 EIE77224.1 - 1.8e-06 27.9 0.7 6.9e-06 26.0 0.0 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein UBN2_2 PF14227.1 EIE77224.1 - 4.3e-05 23.0 1.2 0.00034 20.1 0.1 2.9 3 1 0 3 3 3 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EIE77224.1 - 0.00015 21.5 0.9 0.086 12.6 0.1 2.5 2 0 0 2 2 2 2 gag-polypeptide of LTR copia-type gag-asp_proteas PF13975.1 EIE77224.1 - 0.00066 19.4 0.0 0.0013 18.5 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.5 EIE77225.1 - 7.1e-09 35.2 0.0 1.1e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 EIE77225.1 - 7.1e-09 36.0 0.0 1.4e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.6 EIE77225.1 - 1.7e-06 27.9 0.0 3.2e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EIE77225.1 - 5.5e-06 26.1 0.0 1.1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 EIE77225.1 - 2.1e-05 24.3 0.4 9.6e-05 22.2 0.0 2.2 2 1 0 2 2 2 1 Retroviral aspartyl protease DDE_Tnp_IS1595 PF12762.2 EIE77226.1 - 2.6e-06 27.3 0.1 4.7e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 ISXO2-like transposase domain DUF1759 PF03564.10 EIE77227.1 - 0.00012 21.8 0.4 0.00017 21.4 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) Retrotrans_gag PF03732.12 EIE77227.1 - 0.00057 19.8 0.3 0.0016 18.4 0.0 1.8 2 0 0 2 2 2 1 Retrotransposon gag protein HTH_Tnp_Tc3_2 PF01498.13 EIE77228.1 - 1.2e-05 25.3 0.5 3.1e-05 23.9 0.0 1.9 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 EIE77228.1 - 0.00081 19.5 0.0 0.0019 18.3 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn helix HTH_17 PF12728.2 EIE77228.1 - 0.05 13.8 0.0 0.089 13.0 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.1 EIE77228.1 - 0.11 12.1 0.0 0.36 10.5 0.0 1.8 2 0 0 2 2 2 0 Homeodomain-like domain DUF4119 PF13494.1 EIE77231.1 - 0.16 12.0 2.3 0.25 11.3 0.5 2.0 1 1 1 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF4119) RVT_1 PF00078.22 EIE77232.1 - 4.5e-17 62.1 0.0 8.7e-17 61.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) UBN2_2 PF14227.1 EIE77232.1 - 0.014 14.9 0.1 0.5 9.9 0.0 2.5 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EIE77232.1 - 0.069 12.9 0.4 0.22 11.3 0.0 2.0 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type Chromo PF00385.19 EIE77233.1 - 8.4e-12 44.5 0.6 1.9e-11 43.4 0.4 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DDE_3 PF13358.1 EIE77234.1 - 2.2e-19 69.6 0.0 3.9e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE77234.1 - 7.6e-08 32.3 3.5 7.8e-08 32.2 0.1 2.4 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 EIE77234.1 - 0.0013 18.8 1.5 0.004 17.2 1.0 1.9 1 1 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_ISL3 PF13542.1 EIE77234.1 - 0.047 12.8 0.8 0.047 12.8 0.5 2.4 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 rve PF00665.21 EIE77234.1 - 0.081 13.0 0.0 0.2 11.7 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain HTH_21 PF13276.1 EIE77234.1 - 0.3 11.1 2.7 1.3 9.0 0.0 2.7 3 0 0 3 3 3 0 HTH-like domain HTH_23 PF13384.1 EIE77234.1 - 0.42 10.3 2.9 3.8 7.2 0.2 2.6 2 0 0 2 2 2 0 Homeodomain-like domain HTH_32 PF13565.1 EIE77234.1 - 2.1 9.2 4.8 0.9 10.3 0.5 2.6 4 0 0 4 4 4 0 Homeodomain-like domain zf-H2C2 PF09337.5 EIE77235.1 - 0.0025 17.1 0.2 0.0052 16.1 0.1 1.6 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger TRF PF08558.5 EIE77235.1 - 1.3 8.2 4.6 0.68 9.2 0.5 2.2 2 1 1 3 3 3 0 Telomere repeat binding factor (TRF) Asp_protease PF09668.5 EIE77236.1 - 2.7e-10 39.8 0.0 4.5e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 EIE77236.1 - 4.4e-08 33.5 0.0 1.3e-07 32.0 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.6 EIE77236.1 - 2.4e-06 27.5 0.1 5.9e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.15 EIE77236.1 - 2.9e-06 27.1 0.4 1.4e-05 24.9 0.0 2.3 2 1 1 3 3 3 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EIE77236.1 - 0.00031 20.4 0.1 0.00059 19.5 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Cwf_Cwc_15 PF04889.7 EIE77236.1 - 5.3 6.6 16.9 0.13 12.0 6.5 1.8 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DUF1759 PF03564.10 EIE77237.1 - 0.00021 21.1 0.4 0.00021 21.1 0.3 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1759) DDE_3 PF13358.1 EIE77238.1 - 2.6e-15 56.4 0.1 4.9e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE77238.1 - 4e-10 39.6 1.0 1.1e-09 38.1 0.7 1.8 1 0 0 1 1 1 1 Transposase HTH_Tnp_4 PF13613.1 EIE77238.1 - 0.0049 16.3 0.0 0.01 15.3 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease rve PF00665.21 EIE77240.1 - 1.2e-23 83.4 0.0 3.1e-23 82.1 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE77240.1 - 1.7e-15 56.9 0.3 4e-15 55.7 0.2 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE77240.1 - 4.1e-11 42.3 1.1 9.6e-11 41.1 0.7 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.12 EIE77240.1 - 0.00049 20.1 0.9 0.0024 17.9 0.6 2.2 1 0 0 1 1 1 1 Retrotransposon gag protein zf-H2C2 PF09337.5 EIE77240.1 - 0.0013 18.0 0.1 0.0041 16.4 0.1 1.9 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Asp_protease_2 PF13650.1 EIE77240.1 - 0.0044 17.4 0.2 0.011 16.2 0.2 1.7 1 0 0 1 1 1 1 Aspartyl protease rve_3 PF13683.1 EIE77240.1 - 0.0075 15.7 0.1 0.05 13.1 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain UBN2_2 PF14227.1 EIE77240.1 - 0.024 14.1 5.6 0.049 13.1 0.0 3.3 3 0 0 3 3 3 0 gag-polypeptide of LTR copia-type Asp_protease PF09668.5 EIE77240.1 - 0.043 13.3 0.1 0.13 11.8 0.1 1.8 1 1 0 1 1 1 0 Aspartyl protease UBN2 PF14223.1 EIE77240.1 - 0.06 13.1 0.1 0.22 11.3 0.1 1.9 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Retrotrans_gag PF03732.12 EIE77243.1 - 0.0011 18.9 5.1 0.0014 18.6 0.2 2.9 3 1 0 3 3 3 1 Retrotransposon gag protein Tropomyosin PF00261.15 EIE77243.1 - 0.0091 15.1 6.2 0.014 14.5 4.3 1.3 1 0 0 1 1 1 1 Tropomyosin DUF342 PF03961.8 EIE77243.1 - 0.011 14.2 2.9 0.014 13.8 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) FlxA PF14282.1 EIE77243.1 - 0.05 13.5 5.9 0.056 13.3 1.4 2.1 1 1 1 2 2 2 0 FlxA-like protein V-SNARE PF05008.10 EIE77243.1 - 0.24 11.6 10.6 0.071 13.2 4.5 2.1 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus BLOC1_2 PF10046.4 EIE77243.1 - 0.32 11.1 6.5 2.2 8.4 1.4 2.6 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 IncA PF04156.9 EIE77243.1 - 0.73 9.4 7.2 1.1 8.8 5.0 1.2 1 0 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 EIE77243.1 - 3.4 5.3 8.1 3.6 5.3 5.1 1.4 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family HTH_Tnp_Tc3_2 PF01498.13 EIE77244.1 - 1.1e-15 57.3 0.3 1.3e-15 57.1 0.2 1.1 1 0 0 1 1 1 1 Transposase HTH_12 PF08461.5 EIE77244.1 - 0.01 15.5 1.0 0.051 13.3 0.1 2.0 1 1 1 2 2 2 0 Ribonuclease R winged-helix domain HTH_21 PF13276.1 EIE77244.1 - 0.01 15.7 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 HTH-like domain HTH_29 PF13551.1 EIE77244.1 - 0.012 15.7 0.3 0.022 14.9 0.1 1.5 2 0 0 2 2 2 0 Winged helix-turn helix HTH_32 PF13565.1 EIE77244.1 - 0.036 14.8 0.4 0.5 11.1 0.0 2.1 2 0 0 2 2 2 0 Homeodomain-like domain DDE_Tnp_IS1595 PF12762.2 EIE77245.1 - 1.2e-22 80.4 0.8 2.1e-22 79.6 0.3 1.6 2 0 0 2 2 2 1 ISXO2-like transposase domain DDE_3 PF13358.1 EIE77246.1 - 7.3e-19 67.9 0.4 2.9e-18 66.0 0.0 2.1 3 0 0 3 3 3 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE77246.1 - 1.1e-11 44.5 0.9 2.5e-11 43.4 0.7 1.7 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.1 EIE77246.1 - 0.0048 17.6 0.2 0.51 11.1 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_29 PF13551.1 EIE77246.1 - 0.0066 16.5 0.0 0.018 15.1 0.0 1.8 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EIE77246.1 - 0.017 14.7 0.1 0.098 12.3 0.0 2.4 3 0 0 3 3 3 0 Homeodomain-like domain HTH_28 PF13518.1 EIE77246.1 - 0.073 13.0 0.0 1.1 9.3 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain DDE_3 PF13358.1 EIE77247.1 - 1.5e-17 63.7 0.4 5e-17 62.0 0.0 2.0 3 0 0 3 3 3 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE77247.1 - 1.8e-10 40.7 0.4 4.2e-10 39.5 0.2 1.7 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.1 EIE77247.1 - 0.042 13.9 0.0 0.12 12.5 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn helix DDE_3 PF13358.1 EIE77248.1 - 3.6e-12 46.2 0.2 4.7e-12 45.8 0.2 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Leader_Erm PF08253.6 EIE77249.1 - 0.33 10.4 0.3 0.33 10.4 0.2 2.1 2 0 0 2 2 2 0 Erm Leader peptide DUF4218 PF13960.1 EIE77250.1 - 1e-05 24.9 0.4 1.9e-05 24.0 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) DDE_3 PF13358.1 EIE77252.1 - 3.2e-21 75.5 0.0 6.6e-21 74.5 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE77252.1 - 1.1e-15 57.4 1.9 2.8e-15 56.1 0.3 2.3 3 0 0 3 3 2 1 Transposase HTH_29 PF13551.1 EIE77252.1 - 2.8e-06 27.4 0.2 8.6e-06 25.8 0.2 1.9 2 0 0 2 2 1 1 Winged helix-turn helix HTH_38 PF13936.1 EIE77252.1 - 1.2e-05 24.7 0.1 3.3e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_32 PF13565.1 EIE77252.1 - 7.6e-05 23.4 2.5 0.02 15.6 0.1 3.6 4 0 0 4 4 3 1 Homeodomain-like domain HTH_23 PF13384.1 EIE77252.1 - 7.8e-05 22.1 0.1 0.0028 17.2 0.0 2.7 2 0 0 2 2 2 1 Homeodomain-like domain Sigma70_r4_2 PF08281.7 EIE77252.1 - 0.00055 19.3 0.6 0.024 14.0 0.0 3.2 4 0 0 4 4 4 1 Sigma-70, region 4 HTH_28 PF13518.1 EIE77252.1 - 0.0013 18.6 0.0 0.0056 16.6 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_21 PF13276.1 EIE77252.1 - 0.0019 18.1 0.0 0.13 12.2 0.0 2.6 2 0 0 2 2 2 1 HTH-like domain HTH_7 PF02796.10 EIE77252.1 - 0.0023 17.7 1.1 0.1 12.4 0.0 2.8 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase rve PF00665.21 EIE77252.1 - 0.014 15.4 0.0 0.045 13.8 0.0 2.0 2 0 0 2 2 2 0 Integrase core domain LacI PF00356.16 EIE77252.1 - 0.018 14.6 1.7 2.8 7.6 0.2 2.7 3 0 0 3 3 3 0 Bacterial regulatory proteins, lacI family HTH_Tnp_4 PF13613.1 EIE77252.1 - 0.022 14.2 0.1 0.057 12.9 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease CPSase_L_D3 PF02787.14 EIE77252.1 - 0.06 13.1 0.0 0.14 11.8 0.0 1.6 2 0 0 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain HTH_36 PF13730.1 EIE77252.1 - 0.072 13.2 0.4 4.1 7.6 0.0 3.0 3 0 0 3 3 2 0 Helix-turn-helix domain Sigma70_r4 PF04545.11 EIE77252.1 - 0.1 11.9 0.2 0.79 9.0 0.0 2.5 4 0 0 4 4 4 0 Sigma-70, region 4 HTH_17 PF12728.2 EIE77252.1 - 0.13 12.5 1.7 15 5.9 0.1 3.2 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.1 EIE77252.1 - 0.17 11.0 2.8 8.4 5.6 0.0 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 DDE_3 PF13358.1 EIE77255.1 - 1.3e-12 47.7 0.0 1.5e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE77255.1 - 0.0038 17.3 0.0 0.0083 16.2 0.0 1.5 2 0 0 2 2 2 1 Integrase core domain HTH_Tnp_Tc3_2 PF01498.13 EIE77256.1 - 1.1e-08 34.9 0.7 2.6e-08 33.7 0.5 1.6 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.1 EIE77256.1 - 2.8e-06 27.4 0.6 4e-06 26.9 0.4 1.2 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EIE77256.1 - 4.7e-05 22.8 0.2 0.00075 19.0 0.0 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_7 PF02796.10 EIE77256.1 - 0.008 16.0 0.1 0.88 9.4 0.0 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_28 PF13518.1 EIE77256.1 - 0.032 14.2 0.1 0.092 12.7 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_21 PF13276.1 EIE77256.1 - 0.033 14.2 0.0 0.061 13.3 0.0 1.4 1 0 0 1 1 1 0 HTH-like domain FAM165 PF14981.1 EIE77257.1 - 1.7 8.2 3.6 0.91 9.0 0.2 2.0 1 1 1 2 2 2 0 FAM165 family DDE_3 PF13358.1 EIE77258.1 - 5.9e-18 65.0 0.1 1.2e-17 64.0 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE77258.1 - 3e-10 39.9 0.7 9.4e-10 38.4 0.3 1.9 2 0 0 2 2 2 1 Transposase HTH_Tnp_Tc3_2 PF01498.13 EIE77259.1 - 6.7e-08 32.4 0.1 1.1e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Transposase RVT_1 PF00078.22 EIE77260.1 - 1.1e-17 64.0 0.0 1.8e-17 63.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EIE77261.1 - 8.3e-18 64.6 0.0 3.6e-17 62.5 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 EIE77261.1 - 3.9e-14 52.5 0.9 1e-13 51.1 0.6 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE77261.1 - 1.4e-06 27.8 1.3 5.5e-06 25.9 0.7 2.2 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.1 EIE77261.1 - 0.00023 21.5 0.1 0.0025 18.2 0.0 2.4 2 0 0 2 2 2 1 Aspartyl protease Tudor-knot PF11717.3 EIE77261.1 - 0.019 14.6 0.7 0.052 13.2 0.5 1.7 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain YcgR_2 PF12945.2 EIE77261.1 - 0.027 14.3 0.0 0.41 10.5 0.0 2.5 2 0 0 2 2 2 0 Flagellar protein YcgR gag-asp_proteas PF13975.1 EIE77261.1 - 0.068 13.0 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease rve PF00665.21 EIE77262.1 - 6e-25 87.6 0.0 1.4e-24 86.5 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 EIE77262.1 - 3.1e-11 42.7 0.6 7.8e-11 41.4 0.4 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 EIE77262.1 - 3.1e-05 23.2 0.1 9.4e-05 21.7 0.1 1.9 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger rve_3 PF13683.1 EIE77262.1 - 0.0094 15.4 0.0 0.026 14.0 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain rve PF00665.21 EIE77263.1 - 3.1e-23 82.1 0.0 5.4e-23 81.3 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 EIE77263.1 - 1.9e-08 33.8 0.2 3.5e-08 32.9 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 EIE77263.1 - 0.026 14.2 0.2 0.1 12.3 0.2 2.0 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain DDE_Tnp_IS1595 PF12762.2 EIE77264.1 - 1.2e-22 80.4 0.8 2.1e-22 79.6 0.3 1.6 2 0 0 2 2 2 1 ISXO2-like transposase domain Flu_M2 PF00599.12 EIE77265.1 - 0.064 13.0 0.0 0.067 12.9 0.0 1.0 1 0 0 1 1 1 0 Influenza Matrix protein (M2) Metallophos PF00149.23 EIE77266.1 - 0.1 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase rRNA_processing PF08524.6 EIE77267.1 - 3.1e-11 43.2 40.9 4.5e-09 36.2 20.1 2.1 1 1 1 2 2 2 2 rRNA processing PRP38_assoc PF12871.2 EIE77267.1 - 0.021 15.3 20.6 0.021 15.3 14.3 1.6 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Caldesmon PF02029.10 EIE77267.1 - 0.17 10.2 29.3 0.22 9.9 20.3 1.2 1 0 0 1 1 1 0 Caldesmon DUF2201_N PF13203.1 EIE77267.1 - 1.6 7.8 11.5 2.1 7.4 8.0 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain RR_TM4-6 PF06459.7 EIE77267.1 - 3.5 7.4 18.9 4.4 7.1 13.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 UDPGP PF01704.13 EIE77268.1 - 5.3e-182 605.0 2.1 6.1e-182 604.7 1.4 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase SoxD PF04267.7 EIE77269.1 - 0.26 11.1 1.2 0.39 10.5 0.1 1.8 2 0 0 2 2 2 0 Sarcosine oxidase, delta subunit family DUF2217 PF10265.4 EIE77269.1 - 0.96 8.1 5.2 1.6 7.3 3.6 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DUF59 PF01883.14 EIE77270.1 - 1.1e-09 38.0 0.1 2.3e-09 37.0 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function DUF59 Pkinase PF00069.20 EIE77271.1 - 1.5e-64 217.6 0.0 2.2e-64 217.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE77271.1 - 9.3e-44 149.4 0.0 1.5e-43 148.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 EIE77271.1 - 1.7e-14 53.9 0.6 2.1e-06 28.0 0.1 3.2 3 1 0 3 3 3 2 P21-Rho-binding domain Kinase-like PF14531.1 EIE77271.1 - 2.5e-06 26.6 0.0 6.2e-06 25.3 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EIE77271.1 - 0.0015 17.6 0.2 0.0033 16.4 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIE77271.1 - 0.0027 17.4 0.0 0.093 12.4 0.4 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family DUF2921 PF11145.3 EIE77272.1 - 0.00087 17.1 0.6 0.0015 16.3 0.4 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2921) Vma12 PF11712.3 EIE77272.1 - 0.0029 17.3 0.5 0.0029 17.3 0.3 1.7 2 0 0 2 2 2 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF3366 PF11846.3 EIE77272.1 - 0.0052 16.6 0.6 0.01 15.7 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3366) DUF3439 PF11921.3 EIE77272.1 - 0.0086 15.8 0.4 0.017 14.8 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) Ctr PF04145.10 EIE77272.1 - 0.027 14.4 0.1 0.056 13.5 0.1 1.6 1 0 0 1 1 1 0 Ctr copper transporter family Plasmodium_Vir PF05795.6 EIE77272.1 - 0.042 13.0 0.1 0.085 12.0 0.1 1.4 2 0 0 2 2 2 0 Plasmodium vivax Vir protein DUF788 PF05620.6 EIE77272.1 - 0.25 11.1 2.4 0.56 10.0 1.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF788) Di19_C PF14571.1 EIE77272.1 - 0.61 10.4 6.4 3.8 7.8 4.5 2.2 1 1 0 1 1 1 0 Stress-induced protein Di19, C-terminal FAM176 PF14851.1 EIE77272.1 - 0.64 9.6 3.8 0.21 11.2 0.1 2.0 3 0 0 3 3 3 0 FAM176 family Androgen_recep PF02166.11 EIE77272.1 - 1.4 7.7 5.0 2 7.1 3.4 1.2 1 0 0 1 1 1 0 Androgen receptor SYS1 PF09801.4 EIE77273.1 - 8.8e-31 106.8 11.9 2.5e-30 105.3 6.5 2.0 1 1 1 2 2 2 2 Integral membrane protein S linking to the trans Golgi network tRNA-synt_2 PF00152.15 EIE77274.1 - 2.8e-119 397.8 0.3 6.2e-119 396.6 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EIE77274.1 - 5.3e-08 32.6 0.0 1.5e-07 31.2 0.0 1.8 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.20 EIE77274.1 - 0.00011 21.8 0.9 0.073 12.6 0.2 2.6 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2d PF01409.15 EIE77274.1 - 0.00042 19.5 0.8 0.0015 17.7 0.1 2.1 2 1 0 3 3 3 1 tRNA synthetases class II core domain (F) GAD PF02938.9 EIE77274.1 - 0.031 14.4 0.0 0.092 12.9 0.0 1.7 1 0 0 1 1 1 0 GAD domain DUF883 PF05957.8 EIE77274.1 - 0.51 10.7 21.9 0.071 13.5 5.0 4.2 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF883) ATP-synt_B PF00430.13 EIE77274.1 - 0.93 9.3 19.9 0.8 9.5 3.8 3.4 1 1 1 3 3 3 0 ATP synthase B/B' CF(0) HSA PF07529.8 EIE77275.1 - 0.15 11.8 0.6 2.3 8.0 0.0 2.4 2 0 0 2 2 2 0 HSA PIG-P PF08510.7 EIE77276.1 - 5.5e-15 55.1 2.5 9.7e-15 54.3 1.8 1.4 1 0 0 1 1 1 1 PIG-P Radical_SAM PF04055.16 EIE77277.1 - 9e-14 51.9 0.1 1.3e-13 51.4 0.1 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Gcd10p PF04189.8 EIE77277.1 - 0.02 14.0 2.2 0.031 13.3 1.5 1.2 1 0 0 1 1 1 0 Gcd10p family DUF3573 PF12097.3 EIE77277.1 - 0.21 10.1 0.0 0.28 9.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) LURAP PF14854.1 EIE77278.1 - 0.07 12.8 0.3 0.13 11.9 0.2 1.5 1 0 0 1 1 1 0 Leucine rich adaptor protein UPF0160 PF03690.8 EIE77279.1 - 3.1e-46 158.2 0.1 3.4e-46 158.1 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) UPF0160 PF03690.8 EIE77280.1 - 1.5e-31 110.0 0.1 1.6e-31 109.8 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Glyco_hydro_3 PF00933.16 EIE77281.1 - 1.2e-87 293.6 0.1 1.8e-87 293.1 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EIE77281.1 - 3.5e-63 213.1 0.1 8.1e-63 211.9 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EIE77281.1 - 6.6e-22 77.2 0.0 6.8e-21 73.9 0.0 2.6 2 0 0 2 2 2 1 Fibronectin type III-like domain zf-C2H2 PF00096.21 EIE77282.1 - 0.00059 20.0 5.2 0.0021 18.3 3.6 2.1 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EIE77282.1 - 0.00066 19.4 2.8 0.0018 18.1 1.9 1.8 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_4 PF13894.1 EIE77282.1 - 0.011 16.0 3.4 0.055 13.8 2.3 2.3 1 0 0 1 1 1 0 C2H2-type zinc finger GFA PF04828.9 EIE77282.1 - 0.079 12.9 0.5 0.2 11.6 0.3 1.6 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme zf-C2H2_jaz PF12171.3 EIE77282.1 - 1.5 9.0 7.8 0.24 11.5 2.2 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DDE_3 PF13358.1 EIE77283.1 - 6.8e-22 77.7 0.0 8.5e-22 77.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.14 EIE77283.1 - 6.9e-05 22.0 0.1 8e-05 21.8 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Complex1_LYR_2 PF13233.1 EIE77283.1 - 0.052 14.0 0.7 6.8 7.2 0.1 2.1 1 1 1 2 2 2 0 Complex1_LYR-like DDE_Tnp_ISAZ013 PF07592.6 EIE77283.1 - 0.06 12.0 0.0 0.085 11.5 0.0 1.1 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain AAA_28 PF13521.1 EIE77283.1 - 0.084 12.8 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 AAA domain Chitin_synth_2 PF03142.10 EIE77284.1 - 1.6e-63 214.9 0.0 2.1e-63 214.5 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.1 EIE77284.1 - 2.5e-06 27.4 0.0 0.0022 17.8 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EIE77284.1 - 0.0017 18.0 0.0 0.05 13.2 0.0 2.7 3 0 0 3 3 3 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.1 EIE77284.1 - 0.009 15.7 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.1 EIE77284.1 - 0.014 14.7 0.0 0.024 13.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.4 EIE77284.1 - 0.061 12.4 0.1 1.2 8.1 0.0 2.4 2 0 0 2 2 2 0 Glycosyltransferase like family 2 Ras PF00071.17 EIE77286.1 - 7.5e-66 220.4 1.8 9.1e-66 220.2 1.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIE77286.1 - 1.2e-21 77.4 0.5 2.1e-21 76.5 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EIE77286.1 - 1.4e-18 66.7 0.5 1.6e-18 66.5 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EIE77286.1 - 1e-07 31.3 0.6 1.3e-07 31.0 0.4 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EIE77286.1 - 8e-07 28.6 0.8 1.5e-06 27.7 0.4 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EIE77286.1 - 2.8e-05 23.4 0.1 3.7e-05 23.0 0.1 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EIE77286.1 - 3.2e-05 23.8 0.2 9.9e-05 22.2 0.0 1.8 1 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EIE77286.1 - 0.001 19.1 0.0 0.0021 18.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain Septin PF00735.13 EIE77286.1 - 0.0015 17.5 0.2 0.16 10.9 0.0 2.2 2 0 0 2 2 2 1 Septin AAA_14 PF13173.1 EIE77286.1 - 0.012 15.4 0.2 0.073 12.9 0.1 2.0 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 EIE77286.1 - 0.015 14.4 0.3 0.046 12.8 0.0 2.0 2 1 0 2 2 2 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 EIE77286.1 - 0.016 15.2 0.3 0.041 13.8 0.2 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.24 EIE77286.1 - 0.023 14.9 0.4 0.42 10.8 0.0 2.3 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF3533 PF12051.3 EIE77286.1 - 0.023 13.4 0.8 0.026 13.2 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) ABC_tran PF00005.22 EIE77286.1 - 0.028 14.6 0.2 0.092 13.0 0.1 1.9 1 1 0 1 1 1 0 ABC transporter FeoB_N PF02421.13 EIE77286.1 - 0.035 13.3 0.2 0.39 9.9 0.2 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_29 PF13555.1 EIE77286.1 - 0.039 13.5 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain PduV-EutP PF10662.4 EIE77286.1 - 0.048 13.1 0.2 1.1 8.7 0.0 2.4 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.9 EIE77286.1 - 0.063 13.0 0.0 0.095 12.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) PhyH PF05721.8 EIE77286.1 - 0.12 12.4 0.1 0.15 12.0 0.1 1.1 1 0 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) LUC7 PF03194.10 EIE77286.1 - 0.13 11.7 1.9 0.17 11.4 1.3 1.1 1 0 0 1 1 1 0 LUC7 N_terminus G-alpha PF00503.15 EIE77286.1 - 2.2 6.8 6.1 12 4.4 1.1 2.7 1 1 1 2 2 2 0 G-protein alpha subunit Cellulase PF00150.13 EIE77287.1 - 6.2e-12 45.3 0.3 2e-11 43.6 0.0 1.8 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) DDE_3 PF13358.1 EIE77288.1 - 2e-07 30.8 0.0 2e-07 30.8 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease Methyltransf_11 PF08241.7 EIE77289.1 - 1.3e-07 32.0 0.0 2e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIE77289.1 - 1.2e-06 28.1 0.1 4.4e-06 26.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIE77289.1 - 0.00018 21.8 0.0 0.0037 17.5 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIE77289.1 - 0.00022 20.4 0.1 0.0012 18.0 0.0 2.0 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_29 PF03141.11 EIE77289.1 - 0.0023 16.3 0.0 0.0035 15.7 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_23 PF13489.1 EIE77289.1 - 0.028 14.1 0.0 0.039 13.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.9 EIE77289.1 - 0.11 11.5 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Globin PF00042.17 EIE77290.1 - 0.0035 17.6 0.1 1.8 8.9 0.0 2.4 2 0 0 2 2 2 2 Globin ArfGap PF01412.13 EIE77291.1 - 4.7e-39 132.7 1.6 6.7e-39 132.2 1.1 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Ank_2 PF12796.2 EIE77291.1 - 0.029 14.7 0.0 0.27 11.6 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EIE77291.1 - 0.09 13.0 0.1 1.1 9.5 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeats (many copies) NAPRTase PF04095.11 EIE77292.1 - 1.4e-61 207.8 1.4 1.8e-61 207.5 0.9 1.1 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family 4HBT PF03061.17 EIE77293.1 - 2.2e-06 27.6 0.0 3.4e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily zf-C5HC2 PF02928.11 EIE77294.1 - 0.11 12.5 1.3 4.4 7.4 0.1 2.2 2 0 0 2 2 2 0 C5HC2 zinc finger PIF1 PF05970.9 EIE77295.1 - 4.2e-12 45.6 0.0 4.2e-08 32.5 0.0 2.0 1 1 1 2 2 2 2 PIF1-like helicase GFRP PF06399.8 EIE77296.1 - 0.11 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 GTP cyclohydrolase I feedback regulatory protein (GFRP) Pkinase PF00069.20 EIE77297.1 - 1e-43 149.3 0.0 2.5e-43 148.1 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE77297.1 - 3.8e-09 35.9 0.0 1.4e-08 34.1 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Flu_M1 PF00598.14 EIE77298.1 - 0.12 11.7 0.0 0.19 11.1 0.0 1.4 1 1 0 1 1 1 0 Influenza Matrix protein (M1) JmjC PF02373.17 EIE77299.1 - 7.2e-12 45.5 0.1 2.2e-11 44.0 0.0 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.1 EIE77299.1 - 2.8e-08 33.5 0.0 2.9e-07 30.2 0.0 2.2 1 1 0 1 1 1 1 Cupin-like domain Cupin_2 PF07883.6 EIE77299.1 - 0.0017 17.8 0.0 0.0037 16.7 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Crust_neurohorm PF01147.12 EIE77299.1 - 0.053 12.8 3.7 0.14 11.4 2.6 1.6 1 0 0 1 1 1 0 Crustacean CHH/MIH/GIH neurohormone family FYVE_2 PF02318.11 EIE77299.1 - 0.96 9.3 6.8 0.27 11.1 2.4 1.8 2 0 0 2 2 2 0 FYVE-type zinc finger CybS PF05328.7 EIE77300.1 - 2.2e-35 121.1 0.5 2.6e-35 120.9 0.3 1.1 1 0 0 1 1 1 1 CybS TRAP_alpha PF03896.11 EIE77301.1 - 2.1e-09 36.8 0.2 2.5e-09 36.5 0.1 1.1 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit Aldo_ket_red PF00248.16 EIE77303.1 - 2.1e-78 262.9 0.0 2.6e-78 262.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ECH PF00378.15 EIE77304.1 - 6.7e-49 166.2 0.0 7.7e-49 166.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 EIE77304.1 - 0.019 14.7 0.1 0.18 11.5 0.0 2.1 2 0 0 2 2 2 0 Peptidase family S49 Thioredoxin PF00085.15 EIE77305.1 - 5.8e-66 218.7 7.8 1.4e-33 114.6 0.0 4.7 4 1 0 4 4 4 4 Thioredoxin Thioredoxin_6 PF13848.1 EIE77305.1 - 2.7e-44 151.1 10.6 2.4e-29 102.4 2.2 3.2 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_2 PF13098.1 EIE77305.1 - 3.9e-13 49.5 7.5 0.00033 20.8 0.2 5.3 3 2 1 4 4 4 3 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EIE77305.1 - 1e-12 47.9 3.6 0.025 14.6 0.0 5.8 4 3 2 6 6 6 4 Thioredoxin-like Thioredoxin_7 PF13899.1 EIE77305.1 - 3.9e-10 39.6 0.9 0.012 15.6 0.0 3.9 4 0 0 4 4 4 2 Thioredoxin-like Calsequestrin PF01216.12 EIE77305.1 - 9.6e-06 24.6 2.7 1.8e-05 23.6 0.4 2.5 3 0 0 3 3 3 1 Calsequestrin Thioredoxin_3 PF13192.1 EIE77305.1 - 1.1e-05 25.2 0.0 0.0027 17.4 0.0 3.5 3 0 0 3 3 3 1 Thioredoxin domain ERp29_N PF07912.8 EIE77305.1 - 0.00015 21.6 2.0 1.1 9.1 0.0 4.3 3 1 0 4 4 4 1 ERp29, N-terminal domain Redoxin PF08534.5 EIE77305.1 - 0.0011 18.5 3.4 2.1 7.8 0.0 3.6 3 0 0 3 3 3 2 Redoxin AhpC-TSA PF00578.16 EIE77305.1 - 0.0014 18.3 8.4 0.43 10.2 0.1 3.8 3 1 1 4 4 3 2 AhpC/TSA family HyaE PF07449.6 EIE77305.1 - 0.0016 18.3 0.0 3.9 7.4 0.0 3.8 3 1 0 3 3 3 1 Hydrogenase-1 expression protein HyaE DUF2529 PF10740.4 EIE77305.1 - 0.0023 17.3 0.2 0.0072 15.7 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2529) DUF722 PF05263.6 EIE77305.1 - 0.05 13.7 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF722) TrbC_Ftype PF09673.5 EIE77305.1 - 0.053 13.1 0.0 0.15 11.6 0.0 1.7 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein TrkA_N PF02254.13 EIE77305.1 - 0.11 12.5 0.8 0.34 10.9 0.0 2.2 3 0 0 3 3 3 0 TrkA-N domain Thioredoxin_5 PF13743.1 EIE77305.1 - 0.11 12.0 2.3 0.55 9.7 0.0 3.2 4 1 1 5 5 5 0 Thioredoxin GPI-anchored PF10342.4 EIE77306.1 - 2.4e-11 43.9 0.1 3e-11 43.6 0.1 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.1 EIE77306.1 - 0.0013 18.2 0.0 0.0014 18.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DDE_3 PF13358.1 EIE77307.1 - 3.3e-08 33.3 0.0 7.2e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease ABC_membrane PF00664.18 EIE77309.1 - 1.5e-11 44.2 11.2 3.1e-07 30.1 0.6 3.2 2 1 1 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.22 EIE77309.1 - 3.3e-06 27.4 0.0 1.2e-05 25.5 0.0 2.0 1 1 0 1 1 1 1 ABC transporter Dynamin_N PF00350.18 EIE77309.1 - 0.0031 17.3 0.2 0.0069 16.2 0.1 1.5 1 0 0 1 1 1 1 Dynamin family AAA_29 PF13555.1 EIE77309.1 - 0.028 13.9 0.3 0.11 11.9 0.2 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_23 PF13476.1 EIE77309.1 - 0.085 13.1 0.0 0.98 9.7 0.0 2.3 2 1 0 2 2 2 0 AAA domain Miro PF08477.8 EIE77309.1 - 0.1 13.0 0.1 0.48 10.9 0.1 2.1 2 0 0 2 2 2 0 Miro-like protein AAA_25 PF13481.1 EIE77309.1 - 0.11 11.8 0.0 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 EIE77309.1 - 0.12 11.5 0.1 0.23 10.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ABC_tran PF00005.22 EIE77310.1 - 1.1e-15 58.1 0.0 1.8e-15 57.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SUI1 PF01253.17 EIE77311.1 - 1.3e-26 92.1 3.3 1.6e-26 91.9 2.3 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 HTH_Tnp_Tc3_2 PF01498.13 EIE77312.1 - 4e-06 26.7 1.4 7.4e-06 25.9 0.2 1.9 1 1 1 2 2 2 1 Transposase DEAD_2 PF06733.10 EIE77313.1 - 3.2e-45 153.6 0.1 6.7e-45 152.5 0.0 1.5 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.1 EIE77313.1 - 5.4e-22 78.5 0.0 1.7e-21 76.8 0.0 1.9 1 0 0 1 1 1 1 Helicase C-terminal domain SNF2_N PF00176.18 EIE77313.1 - 0.054 12.2 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 SNF2 family N-terminal domain RGS PF00615.14 EIE77314.1 - 4.7e-08 33.1 1.8 7.3e-08 32.5 0.9 1.6 2 0 0 2 2 2 1 Regulator of G protein signaling domain Smg4_UPF3 PF03467.10 EIE77315.1 - 1.1e-24 87.4 5.5 1.1e-24 87.4 3.8 3.0 2 2 0 2 2 2 1 Smg-4/UPF3 family FancD2 PF14631.1 EIE77315.1 - 1.7 5.6 11.4 2.2 5.2 7.9 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease zf-C2H2 PF00096.21 EIE77316.1 - 1.2e-11 44.2 12.4 1.1e-05 25.4 0.7 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIE77316.1 - 3.8e-11 42.6 13.8 3.4e-08 33.3 2.2 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EIE77316.1 - 5e-08 32.7 11.7 0.00059 19.9 0.8 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EIE77316.1 - 0.00016 21.7 6.7 0.07 13.2 1.1 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.1 EIE77316.1 - 0.00047 19.7 8.8 0.12 12.0 2.2 2.5 2 0 0 2 2 2 2 zinc-finger of a C2HC-type PyrI_C PF02748.10 EIE77316.1 - 0.012 14.9 1.6 0.012 14.9 1.1 2.3 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-Di19 PF05605.7 EIE77316.1 - 0.015 15.4 5.0 0.02 14.9 2.8 1.7 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.1 EIE77316.1 - 0.027 14.6 10.7 0.38 11.0 0.9 2.9 2 1 0 2 2 2 0 C2H2-type zinc-finger domain Prok-RING_1 PF14446.1 EIE77316.1 - 0.039 13.6 5.0 2.7 7.8 0.3 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-met PF12874.2 EIE77316.1 - 0.043 14.0 0.3 0.043 14.0 0.2 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EIE77316.1 - 0.12 12.3 6.7 2.1 8.3 0.3 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EIE77316.1 - 0.13 12.4 11.1 0.41 10.7 0.7 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.10 EIE77316.1 - 0.21 11.3 13.2 0.91 9.3 1.7 2.4 1 1 1 2 2 2 0 BED zinc finger zf-FCS PF06467.9 EIE77316.1 - 0.99 9.1 6.5 72 3.1 5.0 2.5 1 1 1 2 2 2 0 MYM-type Zinc finger with FCS sequence motif Zn-ribbon_8 PF09723.5 EIE77316.1 - 2.9 7.9 7.6 11 6.0 4.6 2.3 1 1 1 2 2 2 0 Zinc ribbon domain zf-LITAF-like PF10601.4 EIE77316.1 - 4.4 7.2 8.8 1.3 8.9 1.5 2.4 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain zf-CHCC PF10276.4 EIE77316.1 - 7.8 6.4 8.3 0.34 10.7 0.6 2.2 2 0 0 2 2 2 0 Zinc-finger domain Pkinase PF00069.20 EIE77317.1 - 3.5e-41 141.0 0.2 1e-29 103.4 0.0 2.6 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIE77317.1 - 2.2e-19 69.5 0.0 6.2e-14 51.6 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EIE77317.1 - 0.00038 19.5 0.0 0.00062 18.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like P34-Arc PF04045.9 EIE77318.1 - 5.4e-101 336.9 1.3 6.9e-101 336.5 0.9 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc ARPC4 PF05856.7 EIE77318.1 - 0.36 10.1 3.0 0.78 9.1 2.1 1.6 1 1 0 1 1 1 0 ARP2/3 complex 20 kDa subunit (ARPC4) Cyclin_N PF00134.18 EIE77319.1 - 0.0069 15.9 0.5 0.021 14.3 0.4 1.8 1 1 0 1 1 1 1 Cyclin, N-terminal domain eIF3_N PF09440.5 EIE77320.1 - 5.2e-24 84.9 1.4 5.2e-24 84.9 0.9 2.7 3 0 0 3 3 3 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 EIE77320.1 - 2.9e-16 59.6 0.7 1.1e-14 54.6 0.2 2.5 2 0 0 2 2 2 1 PCI domain RPN7 PF10602.4 EIE77320.1 - 0.0025 17.2 0.1 0.005 16.2 0.0 1.8 1 1 0 1 1 1 1 26S proteasome subunit RPN7 PCI_Csn8 PF10075.4 EIE77320.1 - 0.0031 17.2 1.9 0.0055 16.4 0.2 2.2 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 B3 PF02362.16 EIE77320.1 - 0.051 13.2 0.0 0.15 11.6 0.0 1.8 1 0 0 1 1 1 0 B3 DNA binding domain XhlA PF10779.4 EIE77320.1 - 0.28 11.1 3.0 1.3 8.9 0.0 3.2 3 0 0 3 3 3 0 Haemolysin XhlA DUF771 PF05595.6 EIE77320.1 - 0.32 10.9 4.8 0.15 12.0 0.2 2.7 3 2 0 3 3 3 0 Domain of unknown function (DUF771) Proteasome PF00227.21 EIE77321.1 - 2.8e-38 131.1 0.0 3.3e-38 130.9 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Ric8 PF10165.4 EIE77322.1 - 5.6e-25 88.0 5.2 6.3e-25 87.9 3.6 1.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn MH1 PF03165.11 EIE77322.1 - 0.089 12.8 0.6 0.18 11.8 0.4 1.5 1 0 0 1 1 1 0 MH1 domain COPI_assoc PF08507.5 EIE77324.1 - 0.0072 16.0 1.2 0.045 13.4 0.9 2.0 1 1 0 1 1 1 1 COPI associated protein Peptidase_M56 PF05569.6 EIE77324.1 - 0.14 11.1 0.0 0.16 10.8 0.0 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 Aldedh PF00171.17 EIE77325.1 - 4.1e-179 595.7 0.0 4.7e-179 595.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EIE77325.1 - 0.0021 17.3 0.0 0.48 9.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) Ribosomal_S8 PF00410.14 EIE77326.1 - 2e-27 95.5 0.0 2.8e-27 95.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 LAGLIDADG_WhiA PF14527.1 EIE77326.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 WhiA LAGLIDADG-like domain MFS_1 PF07690.11 EIE77327.1 - 4.2e-39 134.2 33.6 4.2e-39 134.2 23.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIE77327.1 - 9.4e-16 57.4 21.9 3.6e-15 55.4 15.1 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter Arrestin_C PF02752.17 EIE77328.1 - 2.9e-06 27.4 8.7 0.033 14.2 0.1 3.1 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EIE77328.1 - 0.0042 16.9 4.1 0.22 11.3 0.0 3.9 3 1 0 4 4 4 2 Arrestin (or S-antigen), N-terminal domain L51_S25_CI-B8 PF05047.11 EIE77329.1 - 3.6e-07 29.8 0.1 5.7e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain RasGAP PF00616.14 EIE77330.1 - 1.4e-32 112.9 3.6 1.3e-31 109.8 1.3 2.8 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.1 EIE77330.1 - 6.5e-17 61.8 0.6 2.8e-16 59.7 0.2 2.3 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.15 EIE77330.1 - 3.7e-09 36.2 0.2 1.1e-08 34.7 0.1 1.9 1 0 0 1 1 1 1 CRAL/TRIO domain Sugar_tr PF00083.19 EIE77332.1 - 1.3e-92 310.7 26.1 1.5e-92 310.5 18.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIE77332.1 - 9.1e-29 100.2 22.1 9.1e-29 100.2 15.3 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily EAP30 PF04157.11 EIE77332.1 - 0.1 11.7 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 EAP30/Vps36 family Arrestin_N PF00339.24 EIE77333.1 - 7e-06 25.9 0.0 2.6e-05 24.0 0.0 1.9 3 0 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain 2-Hacid_dh_C PF02826.14 EIE77334.1 - 1.4e-52 177.3 0.0 3.7e-52 176.0 0.0 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EIE77334.1 - 3.7e-35 120.2 0.0 5.2e-35 119.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EIE77334.1 - 0.00016 21.5 0.7 0.0011 18.7 0.1 2.2 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 EIE77334.1 - 0.031 14.1 0.2 0.11 12.2 0.0 1.9 2 1 1 3 3 3 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ACT PF01842.20 EIE77334.1 - 0.097 12.1 0.0 0.3 10.6 0.0 1.9 1 0 0 1 1 1 0 ACT domain Glyco_transf_4 PF13439.1 EIE77334.1 - 0.13 11.9 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Fungal_trans PF04082.13 EIE77335.1 - 1.6e-18 66.5 1.3 3e-18 65.6 0.9 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain ATP-sulfurylase PF01747.12 EIE77336.1 - 9.2e-63 211.4 1.3 1.5e-39 135.5 0.7 2.2 2 0 0 2 2 2 2 ATP-sulfurylase PUA_2 PF14306.1 EIE77336.1 - 1.8e-51 173.7 0.0 2.8e-51 173.1 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain APS_kinase PF01583.15 EIE77336.1 - 7.1e-34 116.7 0.3 1.9e-19 69.8 0.1 2.9 2 1 1 3 3 3 2 Adenylylsulphate kinase KTI12 PF08433.5 EIE77336.1 - 0.0064 15.7 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_18 PF13238.1 EIE77336.1 - 0.012 15.8 0.0 0.035 14.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EIE77336.1 - 0.03 15.1 0.0 0.077 13.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain FAM72 PF14976.1 EIE77338.1 - 5.3e-14 52.2 0.6 1.1e-09 38.3 0.1 2.2 1 1 1 2 2 2 2 FAM72 protein Zn_clus PF00172.13 EIE77339.1 - 4e-06 26.6 6.6 4e-06 26.6 4.6 2.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FlxA PF14282.1 EIE77339.1 - 0.026 14.4 2.5 0.062 13.2 1.7 1.6 1 0 0 1 1 1 0 FlxA-like protein Bromodomain PF00439.20 EIE77340.1 - 2.7e-22 78.4 0.2 8.1e-22 76.9 0.1 1.9 1 0 0 1 1 1 1 Bromodomain AT_hook PF02178.14 EIE77340.1 - 8.5 6.4 10.2 18 5.3 1.5 3.1 2 0 0 2 2 2 0 AT hook motif HlyIII PF03006.15 EIE77341.1 - 1.5e-61 207.6 21.6 1.8e-61 207.3 14.9 1.1 1 0 0 1 1 1 1 Haemolysin-III related LUC7 PF03194.10 EIE77341.1 - 0.45 10.0 5.3 0.7 9.3 3.7 1.3 1 0 0 1 1 1 0 LUC7 N_terminus Syntaxin-6_N PF09177.6 EIE77341.1 - 2.4 8.6 5.1 4.2 7.8 1.0 2.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Exonuc_VII_L PF02601.10 EIE77341.1 - 3.3 6.7 5.4 6.3 5.8 3.8 1.3 1 1 0 1 1 1 0 Exonuclease VII, large subunit CBS PF00571.23 EIE77342.1 - 8.5e-19 67.0 3.1 1.2e-07 31.3 0.0 4.6 4 1 0 4 4 4 4 CBS domain ATP12 PF07542.6 EIE77343.1 - 1.9e-36 124.7 0.6 2.9e-36 124.1 0.4 1.3 1 0 0 1 1 1 1 ATP12 chaperone protein Membr_traf_MHD PF10540.4 EIE77343.1 - 0.037 13.8 0.1 0.091 12.5 0.1 1.8 1 1 0 1 1 1 0 Munc13 (mammalian uncoordinated) homology domain DUF438 PF04282.8 EIE77343.1 - 0.049 13.4 0.1 0.14 11.9 0.1 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF438) Sds3 PF08598.6 EIE77344.1 - 0.0012 18.3 2.0 0.0012 18.3 1.4 2.5 2 2 1 4 4 4 1 Sds3-like DUF4378 PF14309.1 EIE77344.1 - 0.0058 16.7 0.4 0.013 15.5 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4378) Baculo_11_kDa PF06143.6 EIE77344.1 - 2.2 7.6 6.0 0.21 10.9 0.2 2.3 2 1 0 2 2 2 0 Baculovirus 11 kDa family Sugar_tr PF00083.19 EIE77345.1 - 4.1e-123 411.2 24.7 5.5e-123 410.8 17.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIE77345.1 - 4.4e-30 104.5 26.6 4.4e-30 104.5 18.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 EIE77345.1 - 0.0022 16.1 0.2 0.0022 16.1 0.2 2.4 3 0 0 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family DUF441 PF04284.8 EIE77345.1 - 0.0023 17.7 1.1 0.0023 17.7 0.8 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF441) DUF2583 PF10762.4 EIE77345.1 - 6 7.0 7.9 4 7.6 0.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2583) Pkinase PF00069.20 EIE77346.1 - 1.9e-71 240.3 0.0 2.5e-71 239.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE77346.1 - 2.9e-38 131.4 0.0 4e-38 130.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE77346.1 - 0.0016 17.4 0.0 0.004 16.1 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 EIE77346.1 - 0.097 12.3 0.0 0.19 11.4 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Arrestin_N PF00339.24 EIE77347.1 - 2.3e-12 46.9 0.1 3.9e-09 36.4 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EIE77347.1 - 7.7e-08 32.5 0.2 1.7e-07 31.4 0.1 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain DUF2046 PF09755.4 EIE77348.1 - 5.8e-31 107.5 29.8 5.8e-31 107.5 20.7 2.6 1 1 2 3 3 3 1 Uncharacterized conserved protein H4 (DUF2046) Maelstrom PF13017.1 EIE77348.1 - 0.58 9.6 7.2 0.74 9.2 4.4 1.6 1 1 0 1 1 1 0 piRNA pathway germ-plasm component RRM_1 PF00076.17 EIE77351.1 - 6e-28 96.2 0.0 1.2e-13 50.4 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE77351.1 - 4.7e-22 77.7 0.0 1e-09 38.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE77351.1 - 1.9e-16 59.6 0.0 3.8e-09 36.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EIE77351.1 - 0.00035 20.2 0.0 0.011 15.4 0.0 2.7 2 0 0 2 2 2 1 Limkain b1 Nup35_RRM_2 PF14605.1 EIE77351.1 - 0.0015 18.2 0.0 0.27 11.0 0.0 2.5 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RNA_bind PF08675.6 EIE77351.1 - 0.0025 17.7 0.0 1.9 8.5 0.0 2.6 2 0 0 2 2 2 2 RNA binding domain DUF3343 PF11823.3 EIE77351.1 - 0.062 12.5 0.1 5.1 6.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3343) RRM_3 PF08777.6 EIE77351.1 - 0.062 13.1 0.9 5.3 6.9 0.0 3.3 4 0 0 4 4 4 0 RNA binding motif Ribosomal_L7Ae PF01248.21 EIE77352.1 - 8.4e-28 95.7 1.9 1.1e-27 95.4 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF1193 PF06702.7 EIE77352.1 - 0.043 13.2 0.1 0.061 12.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1193) FliM PF02154.10 EIE77352.1 - 0.11 12.1 0.0 0.23 11.0 0.0 1.5 1 1 0 1 1 1 0 Flagellar motor switch protein FliM LRR_8 PF13855.1 EIE77353.1 - 5.7e-06 25.9 13.1 0.32 10.7 0.3 6.4 5 1 1 6 6 6 2 Leucine rich repeat LRR_4 PF12799.2 EIE77353.1 - 0.00075 19.0 14.1 7.3 6.3 1.0 6.1 5 2 1 6 6 6 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EIE77353.1 - 0.004 17.0 15.7 2 8.7 0.1 7.2 7 0 0 7 7 7 2 Leucine Rich repeat LRR_7 PF13504.1 EIE77353.1 - 0.11 12.7 16.8 1.8 9.0 0.0 8.0 10 0 0 10 10 10 0 Leucine rich repeat LRR_1 PF00560.28 EIE77353.1 - 0.73 10.0 12.7 1.1e+02 3.4 0.1 6.9 6 2 1 7 7 7 0 Leucine Rich Repeat DTHCT PF08070.6 EIE77353.1 - 2.8 8.6 13.8 11 6.8 5.3 2.3 2 0 0 2 2 2 0 DTHCT (NUC029) region DUF2217 PF10265.4 EIE77354.1 - 0.14 10.9 0.7 0.16 10.6 0.5 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) AA_kinase PF00696.23 EIE77356.1 - 4.5e-41 140.9 0.1 6.6e-41 140.4 0.1 1.3 1 0 0 1 1 1 1 Amino acid kinase family ACT PF01842.20 EIE77356.1 - 3.2e-13 48.8 0.7 1.4e-07 30.8 0.1 2.5 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.1 EIE77356.1 - 1.6e-12 46.7 3.0 2e-09 36.8 0.8 2.7 2 0 0 2 2 2 2 ACT domain GRAM PF02893.15 EIE77357.1 - 1.4e-18 66.1 0.0 4.2e-18 64.6 0.0 1.8 1 0 0 1 1 1 1 GRAM domain DUF4446 PF14584.1 EIE77357.1 - 1.3 8.7 7.0 0.2 11.4 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) GTP_cyclohydroI PF01227.17 EIE77358.1 - 2.8e-36 124.4 0.0 3.1e-36 124.3 0.0 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I Complex1_LYR PF05347.10 EIE77359.1 - 6.6e-08 32.2 0.6 1.2e-07 31.4 0.4 1.4 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EIE77359.1 - 4.2e-06 26.8 0.5 9e-06 25.8 0.3 1.6 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 EIE77359.1 - 3.3e-05 24.3 0.6 4.1e-05 23.9 0.4 1.2 1 0 0 1 1 1 1 Complex1_LYR-like RhoGEF PF00621.15 EIE77360.1 - 3.3e-36 124.8 0.9 6.2e-36 123.9 0.6 1.5 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.24 EIE77360.1 - 1.4e-05 25.1 1.2 2.3e-05 24.5 0.1 1.9 2 0 0 2 2 2 1 PH domain Caleosin PF05042.8 EIE77361.1 - 4e-33 114.4 0.0 7.5e-33 113.5 0.0 1.4 1 0 0 1 1 1 1 Caleosin related protein Ras PF00071.17 EIE77362.1 - 3.4e-56 189.1 0.0 3.9e-56 188.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIE77362.1 - 3.3e-15 56.6 0.0 4.9e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIE77362.1 - 9.1e-07 28.2 0.0 1.5e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EIE77362.1 - 0.0073 15.5 0.0 0.01 15.1 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EIE77362.1 - 0.14 11.2 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Reprolysin_5 PF13688.1 EIE77363.1 - 1.5e-19 70.7 4.1 1.8e-18 67.1 2.8 2.5 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 EIE77363.1 - 1.2e-18 67.8 0.2 2.9e-18 66.5 0.2 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.18 EIE77363.1 - 1.1e-15 57.5 21.9 1.1e-15 57.5 15.2 4.3 3 2 0 3 3 3 1 Disintegrin Reprolysin_4 PF13583.1 EIE77363.1 - 2.2e-15 56.7 0.5 8.3e-15 54.8 0.4 1.8 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 EIE77363.1 - 3.7e-07 30.7 0.0 6.8e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like DUF2380 PF09533.5 EIE77364.1 - 0.12 11.8 0.3 0.6 9.4 0.0 2.1 2 0 0 2 2 2 0 Predicted lipoprotein of unknown function (DUF2380) Iso_dh PF00180.15 EIE77365.1 - 7.5e-84 281.6 0.1 9.6e-84 281.2 0.1 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Med22 PF06179.7 EIE77366.1 - 1.3e-10 41.2 2.6 3.9e-08 33.2 1.2 2.1 2 0 0 2 2 2 2 Surfeit locus protein 5 subunit 22 of Mediator complex WD40 PF00400.27 EIE77368.1 - 1.2e-68 224.7 14.1 4.8e-13 48.4 0.2 8.1 8 0 0 8 8 8 7 WD domain, G-beta repeat eIF2A PF08662.6 EIE77368.1 - 1.5e-12 47.6 0.6 0.00016 21.4 0.0 3.6 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 EIE77368.1 - 0.0055 16.1 0.0 0.87 9.1 0.0 3.8 5 0 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.1 EIE77368.1 - 0.03 13.4 0.1 0.43 9.6 0.0 2.7 2 1 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Sel1 PF08238.7 EIE77369.1 - 2.1e-37 126.6 31.0 1.3e-06 28.8 0.5 7.4 7 0 0 7 7 7 7 Sel1 repeat MIT PF04212.13 EIE77369.1 - 0.51 10.2 7.3 1.6 8.6 0.0 4.1 3 1 1 4 4 4 0 MIT (microtubule interacting and transport) domain Hexokinase_2 PF03727.11 EIE77371.1 - 1.1e-74 250.7 0.1 1.8e-74 250.0 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EIE77371.1 - 3.3e-67 225.8 0.0 5.7e-67 225.0 0.0 1.4 1 0 0 1 1 1 1 Hexokinase SNF2_N PF00176.18 EIE77372.1 - 2.1e-56 190.9 0.0 2e-52 177.8 0.0 2.3 1 1 1 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 EIE77372.1 - 3.2e-13 49.3 0.0 9e-13 47.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HIRAN PF08797.6 EIE77372.1 - 5.7e-12 45.5 0.0 1.7e-11 44.0 0.0 1.8 2 0 0 2 2 2 1 HIRAN domain zf-C3HC4_3 PF13920.1 EIE77372.1 - 2.4e-08 33.5 4.3 5.1e-08 32.4 3.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIE77372.1 - 5.9e-08 32.6 6.9 1.3e-07 31.5 4.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIE77372.1 - 1.1e-07 31.5 5.5 2.7e-07 30.3 3.8 1.7 1 0 0 1 1 1 1 Ring finger domain UBA_4 PF14555.1 EIE77372.1 - 1.7e-06 27.4 0.0 4.2e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 UBA-like domain zf-RING_5 PF14634.1 EIE77372.1 - 5.8e-06 25.9 5.3 1.2e-05 24.9 3.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EIE77372.1 - 7.7e-05 22.2 3.7 0.00028 20.4 2.8 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) UBA PF00627.26 EIE77372.1 - 9e-05 22.1 0.0 0.0089 15.8 0.0 2.5 2 0 0 2 2 2 1 UBA/TS-N domain DEAD_2 PF06733.10 EIE77372.1 - 0.016 14.6 0.0 0.036 13.4 0.0 1.6 1 0 0 1 1 1 0 DEAD_2 DEAD PF00270.24 EIE77372.1 - 0.034 13.6 0.0 0.074 12.5 0.0 1.6 1 0 0 1 1 1 0 DEAD/DEAH box helicase zf-C3HC4_4 PF15227.1 EIE77372.1 - 0.62 9.9 7.7 2.9 7.8 5.4 2.1 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING WD40 PF00400.27 EIE77373.1 - 3e-40 134.6 3.4 3.7e-08 32.9 0.0 5.3 5 0 0 5 5 5 5 WD domain, G-beta repeat PRP4 PF08799.6 EIE77373.1 - 2.2e-09 36.4 4.7 4.6e-09 35.3 3.3 1.6 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like eIF2A PF08662.6 EIE77373.1 - 0.0015 18.3 0.0 0.31 10.7 0.0 2.8 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 EIE77373.1 - 0.061 12.4 0.0 0.82 8.7 0.0 2.1 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Abhydrolase_3 PF07859.8 EIE77374.1 - 7.9e-30 104.0 0.0 2.2e-22 79.6 0.0 2.5 1 1 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 EIE77374.1 - 1.6e-09 36.9 0.0 2.4e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Peptidase_S9 PF00326.16 EIE77374.1 - 0.00058 19.1 0.0 0.0011 18.1 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.7 EIE77374.1 - 0.12 10.8 0.0 0.18 10.2 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_5 PF12695.2 EIE77374.1 - 0.15 11.8 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family PepSY PF03413.14 EIE77374.1 - 0.28 11.8 1.5 0.93 10.1 0.1 2.3 3 0 0 3 3 3 0 Peptidase propeptide and YPEB domain eIF3g PF12353.3 EIE77376.1 - 7 6.5 8.3 16 5.3 5.8 1.8 1 1 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G PLDc PF00614.17 EIE77377.1 - 9.2e-16 57.0 1.0 2.9e-09 36.4 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 EIE77377.1 - 1.7e-11 43.9 0.0 2.2e-07 30.6 0.0 3.1 3 0 0 3 3 3 2 PLD-like domain PIN_4 PF13638.1 EIE77378.1 - 1.1e-21 77.2 0.2 3.6e-21 75.6 0.2 1.9 1 0 0 1 1 1 1 PIN domain EST1_DNA_bind PF10373.4 EIE77378.1 - 5.1e-06 25.9 1.1 6.1e-05 22.3 0.2 3.0 2 1 0 2 2 2 1 Est1 DNA/RNA binding domain Melibiase PF02065.13 EIE77379.1 - 7.6e-07 28.1 0.3 2.4e-06 26.5 0.0 1.9 2 1 0 2 2 2 1 Melibiase Glyco_hydro_53 PF07745.8 EIE77379.1 - 0.07 11.9 0.2 0.1 11.3 0.2 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 53 Choline_kinase PF01633.15 EIE77380.1 - 4e-65 219.3 0.1 6.1e-65 218.7 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 EIE77380.1 - 3.4e-16 59.6 0.0 5.1e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EIE77380.1 - 0.017 14.2 0.0 0.026 13.6 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Ribosomal_L18ae PF01775.12 EIE77381.1 - 3.2e-46 156.2 3.7 4e-46 155.9 2.5 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain SMC_N PF02463.14 EIE77382.1 - 6.2e-42 143.3 14.0 1.4e-41 142.1 9.7 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EIE77382.1 - 4.5e-28 97.6 0.0 1.7e-27 95.7 0.0 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EIE77382.1 - 2.1e-05 24.6 0.3 2.1e-05 24.6 0.2 2.9 2 2 0 2 2 2 1 AAA domain Reo_sigmaC PF04582.7 EIE77382.1 - 0.0012 18.1 14.1 0.025 13.7 0.2 3.8 2 1 1 3 3 3 3 Reovirus sigma C capsid protein SbcCD_C PF13558.1 EIE77382.1 - 0.0013 18.5 0.0 0.01 15.7 0.0 2.6 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Spc7 PF08317.6 EIE77382.1 - 0.004 15.8 3.1 0.004 15.8 2.1 7.3 4 2 2 7 7 7 2 Spc7 kinetochore protein DUF1664 PF07889.7 EIE77382.1 - 0.012 15.3 1.2 0.012 15.3 0.8 7.7 5 3 3 9 9 9 0 Protein of unknown function (DUF1664) OST3_OST6 PF04756.8 EIE77383.1 - 1.2e-15 57.3 0.8 3.2e-15 56.0 0.1 1.8 2 0 0 2 2 2 1 OST3 / OST6 family Thioredoxin PF00085.15 EIE77383.1 - 0.0015 18.1 0.0 0.0028 17.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin COX4_pro_2 PF07835.7 EIE77383.1 - 0.012 15.5 1.0 0.036 14.0 0.7 1.8 1 0 0 1 1 1 0 Bacterial aa3 type cytochrome c oxidase subunit IV ATP-synt_Eps PF04627.8 EIE77384.1 - 1.6e-24 85.1 2.4 1.9e-24 84.9 1.7 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain NAC PF01849.13 EIE77385.1 - 4.3e-18 64.5 0.4 1.4e-16 59.7 0.0 2.5 2 0 0 2 2 2 1 NAC domain UBA PF00627.26 EIE77385.1 - 4.1e-05 23.2 0.3 4.1e-05 23.2 0.2 1.8 2 0 0 2 2 2 1 UBA/TS-N domain UBA_4 PF14555.1 EIE77385.1 - 0.057 12.9 0.1 0.1 12.1 0.1 1.4 1 0 0 1 1 1 0 UBA-like domain DUF4637 PF15470.1 EIE77385.1 - 0.21 11.2 6.1 0.29 10.7 4.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Ribosomal_S13 PF00416.17 EIE77385.1 - 0.23 11.9 1.5 1 9.8 0.2 2.1 2 0 0 2 2 2 0 Ribosomal protein S13/S18 DUF3987 PF13148.1 EIE77385.1 - 0.96 7.9 6.1 1.3 7.5 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) EBV-NA3 PF05009.7 EIE77385.1 - 1.6 7.9 4.0 2.2 7.4 2.8 1.2 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Lipase_chap PF03280.9 EIE77385.1 - 5.3 6.5 12.6 0.24 10.8 5.1 1.4 2 0 0 2 2 2 0 Proteobacterial lipase chaperone protein FMN_red PF03358.10 EIE77387.1 - 5.3e-12 45.4 0.0 8.2e-12 44.8 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 EIE77387.1 - 3.3e-06 26.7 0.0 4.9e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.20 EIE77387.1 - 0.00026 21.0 0.0 0.00073 19.5 0.0 2.0 1 1 1 2 2 2 1 Flavodoxin Asparaginase_2 PF01112.13 EIE77388.1 - 2e-21 76.0 0.0 3e-21 75.4 0.0 1.2 1 0 0 1 1 1 1 Asparaginase G_glu_transpept PF01019.16 EIE77388.1 - 0.11 11.0 0.0 0.14 10.6 0.0 1.1 1 0 0 1 1 1 0 Gamma-glutamyltranspeptidase FMN_red PF03358.10 EIE77389.1 - 1.6e-15 56.8 0.0 2.3e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 EIE77389.1 - 1.8e-07 30.8 0.0 2.3e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.20 EIE77389.1 - 3.4e-05 23.8 0.0 6.9e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NosD PF05048.8 EIE77390.1 - 0.27 10.3 2.9 0.43 9.7 2.0 1.3 1 1 0 1 1 1 0 Periplasmic copper-binding protein (NosD) zf-C2H2 PF00096.21 EIE77391.1 - 0.00012 22.1 18.3 0.00054 20.1 2.8 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIE77391.1 - 0.001 19.2 4.4 0.001 19.2 3.0 2.9 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EIE77391.1 - 0.0012 18.9 1.0 0.0049 16.9 0.7 2.2 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 EIE77391.1 - 0.0022 18.1 2.2 0.0022 18.1 1.5 3.6 3 0 0 3 3 3 1 C2H2-type zinc finger PyrI_C PF02748.10 EIE77391.1 - 0.046 13.1 0.9 0.15 11.5 0.6 1.8 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain AMP-binding PF00501.23 EIE77392.1 - 1.3e-41 142.4 0.0 1.4e-31 109.3 0.0 2.1 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 EIE77392.1 - 2.3e-12 47.6 0.0 4.3e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ILVD_EDD PF00920.16 EIE77393.1 - 1e-212 707.2 0.1 1.2e-212 707.0 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family Vps5 PF09325.5 EIE77394.1 - 3.1e-20 72.4 15.2 6.8e-12 45.1 4.0 2.2 1 1 1 2 2 2 2 Vps5 C terminal like BAR PF03114.13 EIE77394.1 - 3.6e-05 23.4 15.9 0.00012 21.6 11.0 1.9 1 1 0 1 1 1 1 BAR domain Baculo_PEP_C PF04513.7 EIE77394.1 - 0.00016 21.5 0.6 0.026 14.3 0.0 2.3 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus EMP24_GP25L PF01105.19 EIE77394.1 - 0.0075 16.0 2.6 0.063 12.9 0.1 2.3 2 0 0 2 2 2 1 emp24/gp25L/p24 family/GOLD NPV_P10 PF05531.7 EIE77394.1 - 0.01 16.0 1.3 5.8 7.2 0.1 2.9 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein IncA PF04156.9 EIE77394.1 - 0.019 14.5 10.9 0.18 11.3 2.5 2.4 2 0 0 2 2 2 0 IncA protein TBPIP PF07106.8 EIE77394.1 - 0.026 14.0 10.5 0.22 11.0 1.9 2.4 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) PNPase PF03726.9 EIE77394.1 - 0.049 13.9 3.9 0.22 11.8 1.3 2.5 2 0 0 2 2 2 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain P4Ha_N PF08336.6 EIE77394.1 - 0.076 12.8 9.0 1.7 8.4 0.3 3.2 2 1 1 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Fib_alpha PF08702.5 EIE77394.1 - 0.08 13.0 5.2 0.4 10.8 0.2 2.6 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF948 PF06103.6 EIE77394.1 - 0.088 12.6 2.8 9.6 6.1 0.1 3.4 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Prefoldin_2 PF01920.15 EIE77394.1 - 0.13 12.0 8.9 1.6 8.5 0.1 3.3 2 1 0 3 3 3 0 Prefoldin subunit Hemerythrin PF01814.18 EIE77394.1 - 0.14 12.3 5.6 2.6 8.2 0.7 3.0 2 1 1 3 3 3 0 Hemerythrin HHE cation binding domain LOH1CR12 PF10158.4 EIE77394.1 - 0.32 10.7 5.4 0.21 11.3 0.3 2.6 2 0 0 2 2 2 0 Tumour suppressor protein FAM92 PF06730.6 EIE77394.1 - 0.33 10.2 12.8 1.1 8.5 2.8 2.2 1 1 1 2 2 2 0 FAM92 protein Seryl_tRNA_N PF02403.17 EIE77394.1 - 0.39 10.7 10.5 0.26 11.3 1.0 3.1 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF3573 PF12097.3 EIE77394.1 - 0.69 8.4 4.1 2 6.9 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3573) TMF_TATA_bd PF12325.3 EIE77394.1 - 0.75 9.5 14.3 1.3 8.7 2.2 2.7 3 0 0 3 3 2 0 TATA element modulatory factor 1 TATA binding DUF4164 PF13747.1 EIE77394.1 - 0.75 9.9 10.2 0.69 10.0 1.2 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) DUF4140 PF13600.1 EIE77394.1 - 0.84 10.1 7.5 1.4 9.3 1.9 2.8 2 2 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) GrpE PF01025.14 EIE77394.1 - 1.2 8.6 14.5 0.027 14.0 1.3 2.9 1 1 0 2 2 2 0 GrpE XhlA PF10779.4 EIE77394.1 - 1.3 8.9 7.6 1.8 8.5 0.8 2.8 2 0 0 2 2 2 0 Haemolysin XhlA DivIC PF04977.10 EIE77394.1 - 1.7 8.1 7.2 2.5 7.6 1.6 2.6 2 0 0 2 2 2 0 Septum formation initiator F_actin_bind PF08919.5 EIE77394.1 - 2.3 7.9 10.9 2.5 7.8 0.4 3.7 1 1 1 3 3 3 0 F-actin binding Drf_GBD PF06371.8 EIE77395.1 - 2.7e-16 59.4 1.2 1.8e-15 56.8 0.3 2.5 2 1 0 2 2 2 1 Diaphanous GTPase-binding Domain SNF2_N PF00176.18 EIE77396.1 - 1.7e-83 279.9 1.4 1.7e-83 279.9 1.0 2.8 3 1 0 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EIE77396.1 - 2.2e-17 62.6 0.0 1.4e-16 60.0 0.0 2.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HSA PF07529.8 EIE77396.1 - 1e-16 60.4 9.3 1e-16 60.4 6.5 3.6 3 0 0 3 3 3 1 HSA SnAC PF14619.1 EIE77396.1 - 2.8e-13 49.8 0.4 2.8e-13 49.8 0.3 3.4 3 1 0 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex PAS_3 PF08447.6 EIE77397.1 - 1.4e-12 47.4 0.0 2.6e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS PF00989.19 EIE77397.1 - 6.6e-10 38.7 0.0 1e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.1 EIE77397.1 - 5.4e-09 36.3 0.0 1.6e-08 34.8 0.0 1.8 2 0 0 2 2 2 1 PAS domain PAS_11 PF14598.1 EIE77397.1 - 2.9e-07 30.4 0.0 4.6e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.5 EIE77397.1 - 0.03 14.3 0.0 0.052 13.5 0.0 1.4 1 0 0 1 1 1 0 PAS fold YlbD_coat PF14071.1 EIE77398.1 - 0.009 16.0 0.4 0.011 15.7 0.2 1.3 1 1 0 1 1 1 1 Putative coat protein DUF773 PF05600.7 EIE77398.1 - 0.14 10.9 0.2 0.15 10.8 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF773) RVT_1 PF00078.22 EIE77399.1 - 0.098 12.0 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Glyco_transf_15 PF01793.11 EIE77400.1 - 1.8e-80 270.3 20.2 2.6e-44 151.5 2.5 3.0 1 1 2 3 3 3 3 Glycolipid 2-alpha-mannosyltransferase PAP_central PF04928.12 EIE77401.1 - 7.3e-82 273.9 0.0 1.2e-81 273.2 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 EIE77401.1 - 2.1e-14 53.3 0.1 3.3e-14 52.6 0.1 1.4 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 EIE77401.1 - 7.9e-07 29.3 0.0 2.7e-06 27.6 0.0 1.9 1 0 0 1 1 1 1 Nucleotidyltransferase domain SHS2_Rpb7-N PF03876.12 EIE77402.1 - 2.1e-18 66.2 0.7 3.1e-18 65.6 0.5 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RNA_pol_Rbc25 PF08292.7 EIE77402.1 - 2.2e-11 44.0 0.0 3.3e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 S1 PF00575.18 EIE77402.1 - 0.045 13.8 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 S1 RNA binding domain UBA PF00627.26 EIE77403.1 - 2.4e-06 27.2 0.2 4.1e-06 26.4 0.1 1.4 1 0 0 1 1 1 1 UBA/TS-N domain DUF605 PF04652.11 EIE77403.1 - 0.24 10.7 17.3 0.31 10.4 12.0 1.1 1 0 0 1 1 1 0 Vta1 like 5_nucleotid_C PF02872.13 EIE77404.1 - 0.0024 17.8 0.0 0.0079 16.1 0.0 1.9 2 0 0 2 2 2 1 5'-nucleotidase, C-terminal domain B12-binding PF02310.14 EIE77404.1 - 0.068 13.0 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 B12 binding domain Ribosomal_S25 PF03297.10 EIE77405.1 - 1.6e-41 140.6 2.9 1.9e-41 140.3 2.0 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_24 PF13412.1 EIE77405.1 - 0.0068 15.7 0.5 0.013 14.9 0.3 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding BioT2 PF15368.1 EIE77405.1 - 0.017 14.8 0.2 0.021 14.5 0.2 1.2 1 0 0 1 1 1 0 Spermatogenesis family BioT2 MarR_2 PF12802.2 EIE77405.1 - 0.055 13.1 0.0 0.076 12.6 0.0 1.3 1 0 0 1 1 1 0 MarR family INTS2 PF14750.1 EIE77406.1 - 4.3e-47 160.3 5.0 2.7e-38 131.1 1.1 3.0 1 1 2 3 3 3 3 Integrator complex subunit 2 Sec63 PF02889.11 EIE77406.1 - 0.015 14.5 0.0 0.024 13.8 0.0 1.3 1 0 0 1 1 1 0 Sec63 Brl domain Fibrillarin PF01269.12 EIE77407.1 - 1.2e-111 371.2 0.1 1.4e-111 370.9 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 EIE77407.1 - 2.8e-05 23.7 0.0 4.3e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.1 EIE77407.1 - 0.00033 20.2 0.0 0.00044 19.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EIE77407.1 - 0.016 14.7 0.0 0.022 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF2462 PF09495.5 EIE77408.1 - 1.3e-14 54.6 16.9 1.3e-14 54.6 11.7 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2462) PP2C_C PF07830.8 EIE77408.1 - 0.0077 16.3 0.3 0.0099 15.9 0.2 1.2 1 0 0 1 1 1 1 Protein serine/threonine phosphatase 2C, C-terminal domain DUF1484 PF07363.6 EIE77408.1 - 0.057 13.7 0.7 0.074 13.3 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1484) zf-HC5HC2H_2 PF13832.1 EIE77409.1 - 1.9e-34 117.9 9.3 1.9e-34 117.9 6.5 2.7 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EIE77409.1 - 8.3e-26 89.9 7.1 8.3e-26 89.9 4.9 3.4 3 0 0 3 3 3 1 PHD-like zinc-binding domain Bromodomain PF00439.20 EIE77409.1 - 7.6e-24 83.4 0.6 1.8e-23 82.2 0.4 1.7 1 0 0 1 1 1 1 Bromodomain EPL1 PF10513.4 EIE77409.1 - 2.7e-23 83.0 9.1 2.7e-23 83.0 6.3 3.9 2 1 0 2 2 2 1 Enhancer of polycomb-like PHD_2 PF13831.1 EIE77409.1 - 2.9e-14 52.0 4.0 2.9e-14 52.0 2.8 2.6 3 0 0 3 3 3 1 PHD-finger PHD PF00628.24 EIE77409.1 - 4.9e-11 42.1 26.9 5.8e-10 38.7 4.6 3.0 3 0 0 3 3 3 2 PHD-finger C1_1 PF00130.17 EIE77409.1 - 0.0057 16.3 0.2 0.0057 16.3 0.1 2.8 3 0 0 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 EIE77409.1 - 0.26 11.0 18.3 0.014 15.1 2.4 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Nop14 PF04147.7 EIE77410.1 - 1.6 6.5 42.8 2.5 5.9 29.7 1.3 1 0 0 1 1 1 0 Nop14-like family CM_2 PF01817.16 EIE77411.1 - 2e-06 27.7 1.1 0.0018 18.3 0.0 3.0 2 1 0 2 2 2 2 Chorismate mutase type II Rhomboid PF01694.17 EIE77413.1 - 2.2e-31 108.8 7.3 3.6e-31 108.1 5.0 1.3 1 0 0 1 1 1 1 Rhomboid family DUF95 PF01944.12 EIE77413.1 - 0.013 15.1 0.3 0.028 14.0 0.2 1.5 1 0 0 1 1 1 0 Integral membrane protein DUF95 DUF2177 PF09945.4 EIE77413.1 - 0.061 13.3 0.4 0.11 12.5 0.3 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2177) Sod_Cu PF00080.15 EIE77414.1 - 8.7e-45 152.3 0.9 1.1e-44 152.0 0.7 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) DUF2272 PF10030.4 EIE77415.1 - 0.096 12.1 1.9 0.1 12.0 1.3 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2272) zf-C5HC2 PF02928.11 EIE77416.1 - 0.092 12.8 1.0 4.4 7.4 0.1 2.2 2 0 0 2 2 2 0 C5HC2 zinc finger Fer4_18 PF13746.1 EIE77416.1 - 0.37 11.2 2.6 0.44 10.9 1.2 1.6 1 1 0 1 1 1 0 4Fe-4S dicluster domain Asp PF00026.18 EIE77417.1 - 6.4e-90 301.6 0.3 8e-90 301.2 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIE77417.1 - 1.7e-08 34.6 0.1 7.7e-08 32.4 0.1 1.9 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EIE77417.1 - 0.00018 21.9 0.1 0.058 13.8 0.0 2.6 2 1 0 2 2 2 2 Aspartyl protease DUF1212 PF06738.7 EIE77418.1 - 2.4e-29 102.1 16.3 3e-24 85.5 1.2 3.4 2 1 0 2 2 2 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 EIE77418.1 - 1.3e-15 57.4 21.7 4.1e-14 52.6 7.7 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3815) Cpn60_TCP1 PF00118.19 EIE77419.1 - 9.6e-120 400.4 6.2 1.1e-119 400.2 4.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family zf-C2H2_4 PF13894.1 EIE77420.1 - 0.00058 20.0 14.7 0.077 13.3 0.5 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EIE77420.1 - 0.0012 19.0 19.6 0.031 14.6 0.2 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EIE77420.1 - 0.0016 18.5 0.3 1 9.5 0.0 2.7 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding OAF PF14941.1 EIE77420.1 - 0.45 9.6 3.6 0.63 9.1 0.2 2.2 1 1 1 2 2 2 0 Transcriptional regulator, Out at first Streptin-Immun PF11083.3 EIE77421.1 - 0.16 11.9 2.4 0.33 10.9 1.7 1.6 1 0 0 1 1 1 0 Lantibiotic streptin immunity protein CRAL_TRIO PF00650.15 EIE77422.1 - 1e-28 99.7 0.0 1.4e-28 99.4 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain Med21 PF11221.3 EIE77422.1 - 0.0014 18.5 1.0 0.0027 17.6 0.7 1.4 1 0 0 1 1 1 1 Subunit 21 of Mediator complex CRAL_TRIO_2 PF13716.1 EIE77422.1 - 0.0041 17.0 0.0 0.0094 15.8 0.0 1.6 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain WD40 PF00400.27 EIE77423.1 - 2.3e-41 138.2 5.2 4.6e-08 32.6 0.1 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 EIE77423.1 - 1.2e-10 40.2 8.1 0.0015 16.7 0.0 4.3 1 1 3 4 4 4 4 Nucleoporin Nup120/160 F-box-like PF12937.2 EIE77423.1 - 7e-09 35.2 0.2 1.6e-08 34.1 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIE77423.1 - 0.00046 19.7 0.2 0.0013 18.2 0.1 1.8 1 0 0 1 1 1 1 F-box domain PQQ_3 PF13570.1 EIE77423.1 - 0.0065 16.7 0.3 17 5.8 0.0 3.8 3 0 0 3 3 3 1 PQQ-like domain YopR_core PF09025.5 EIE77423.1 - 0.029 14.3 0.1 0.065 13.2 0.0 1.5 2 0 0 2 2 2 0 YopR Core PRANC PF09372.5 EIE77423.1 - 0.22 11.5 1.2 0.37 10.8 0.1 1.9 2 0 0 2 2 2 0 PRANC domain SNARE PF05739.14 EIE77424.1 - 1.1e-16 60.2 6.9 1.1e-16 60.2 4.8 1.7 2 0 0 2 2 1 1 SNARE domain Vac_Fusion PF02346.11 EIE77424.1 - 0.00015 21.1 0.3 0.00032 20.0 0.0 1.7 2 0 0 2 2 2 1 Chordopoxvirus fusion protein DUF4094 PF13334.1 EIE77424.1 - 0.0036 17.6 2.3 0.0036 17.6 1.6 2.7 2 1 1 3 3 3 1 Domain of unknown function (DUF4094) YukC PF10140.4 EIE77424.1 - 0.0083 14.7 1.2 0.012 14.1 0.2 1.6 1 1 1 2 2 2 1 WXG100 protein secretion system (Wss), protein YukC R-HINP1I PF11463.3 EIE77424.1 - 0.01 15.2 1.6 0.014 14.7 1.1 1.2 1 0 0 1 1 1 0 R.HinP1I restriction endonuclease MCPsignal PF00015.16 EIE77424.1 - 0.022 14.3 9.0 0.028 13.9 6.3 1.3 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF3394 PF11874.3 EIE77424.1 - 0.023 14.2 0.8 0.029 13.9 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3394) DctQ PF04290.7 EIE77424.1 - 0.074 12.8 0.8 0.11 12.2 0.6 1.2 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component TRAP_beta PF05753.9 EIE77424.1 - 0.1 11.7 0.2 0.18 10.9 0.1 1.4 1 0 0 1 1 1 0 Translocon-associated protein beta (TRAPB) Bromo_MP PF01573.11 EIE77424.1 - 0.13 11.2 4.5 0.16 10.9 3.1 1.1 1 0 0 1 1 1 0 Bromovirus movement protein PspA_IM30 PF04012.7 EIE77424.1 - 0.16 11.3 8.4 0.19 11.0 5.8 1.2 1 0 0 1 1 1 0 PspA/IM30 family Rifin_STEVOR PF02009.11 EIE77424.1 - 0.3 10.7 6.3 0.45 10.1 4.4 1.3 1 1 0 1 1 1 0 Rifin/stevor family 7tm_7 PF08395.7 EIE77424.1 - 0.33 9.9 5.7 3.4 6.6 0.2 2.1 2 0 0 2 2 2 0 7tm Chemosensory receptor DUF3829 PF12889.2 EIE77424.1 - 0.54 9.4 5.3 0.64 9.1 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) DUF3018 PF11455.3 EIE77424.1 - 0.55 10.2 2.8 0.55 10.1 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3018) DUF745 PF05335.8 EIE77424.1 - 0.77 9.2 9.8 0.94 8.9 6.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF745) MalF_P2 PF14785.1 EIE77424.1 - 0.92 9.3 3.7 1.1 9.0 2.6 1.1 1 0 0 1 1 1 0 Maltose transport system permease protein MalF P2 domain Med28 PF11594.3 EIE77424.1 - 1.1 9.4 7.7 4.7 7.5 5.3 1.9 1 1 0 1 1 1 0 Mediator complex subunit 28 DUF4337 PF14235.1 EIE77424.1 - 2.1 8.1 7.6 2.4 7.9 4.6 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) Fib_alpha PF08702.5 EIE77424.1 - 2.3 8.3 10.5 3.5 7.7 7.3 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF2203 PF09969.4 EIE77424.1 - 2.8 8.1 6.0 0.69 10.1 1.4 1.8 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Atg14 PF10186.4 EIE77424.1 - 4.4 6.1 7.5 6.2 5.6 5.2 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 zf-C2H2_2 PF12756.2 EIE77425.1 - 0.0019 18.3 0.5 0.0029 17.6 0.4 1.4 1 1 0 1 1 1 1 C2H2 type zinc-finger (2 copies) DUF4428 PF14471.1 EIE77425.1 - 0.01 15.5 0.0 0.02 14.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) zf-C2H2_4 PF13894.1 EIE77425.1 - 0.024 14.9 1.6 0.024 14.9 1.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EIE77425.1 - 0.088 13.1 0.8 0.088 13.1 0.6 2.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type DUF629 PF04780.7 EIE77425.1 - 1.7 7.0 4.4 2.6 6.4 0.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF629) zf-C2H2_2 PF12756.2 EIE77427.1 - 3.7e-40 136.1 15.3 1.4e-31 108.5 0.1 3.5 2 1 1 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 EIE77427.1 - 2.2e-08 33.9 22.6 7.1e-06 26.0 5.8 3.3 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EIE77427.1 - 2.4e-06 27.5 14.4 1.8e-05 24.7 4.4 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-DBF PF07535.7 EIE77427.1 - 0.0014 18.3 3.5 0.0014 18.3 2.4 3.0 4 0 0 4 4 4 1 DBF zinc finger zf-LYAR PF08790.6 EIE77427.1 - 0.15 11.7 6.7 0.2 11.3 0.2 2.7 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger UPF0560 PF10577.4 EIE77427.1 - 0.43 8.7 9.3 0.55 8.4 6.5 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 AKAP95 PF04988.7 EIE77427.1 - 3.8 7.2 16.1 6.2 6.5 0.2 3.7 2 1 1 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) Phage_integrase PF00589.17 EIE77430.1 - 2.2e-05 24.1 0.0 4.4e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Phage integrase family ATP_transf PF09830.4 EIE77433.1 - 0.052 13.3 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 ATP adenylyltransferase Pox_TAP PF03355.9 EIE77436.1 - 0.11 11.8 0.0 0.11 11.8 0.0 1.0 1 0 0 1 1 1 0 Viral Trans-Activator Protein rve PF00665.21 EIE77438.1 - 4.4e-21 75.2 0.0 1.8e-20 73.2 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 EIE77438.1 - 5.3e-16 58.6 0.0 1e-15 57.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 EIE77438.1 - 1e-07 32.3 0.3 2.3e-07 31.2 0.1 1.8 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.1 EIE77438.1 - 3.1e-06 26.9 0.1 6.1e-06 25.9 0.1 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 EIE77438.1 - 5.6e-06 26.3 0.0 1.1e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 EIE77438.1 - 0.00093 18.7 0.1 0.0025 17.3 0.1 1.7 1 0 0 1 1 1 1 Aspartyl protease rve_3 PF13683.1 EIE77438.1 - 0.0024 17.3 0.0 0.0078 15.7 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVP PF00077.15 EIE77438.1 - 0.024 14.5 0.0 0.073 12.9 0.0 1.8 1 0 0 1 1 1 0 Retroviral aspartyl protease MIS13 PF08202.6 EIE77439.1 - 0.02 13.9 2.8 0.024 13.7 1.9 1.2 1 0 0 1 1 1 0 Mis12-Mtw1 protein family YvrJ PF12841.2 EIE77439.1 - 0.028 13.7 0.5 0.067 12.4 0.4 1.6 1 0 0 1 1 1 0 YvrJ protein family zf-RVT PF13966.1 EIE77440.1 - 2.8e-07 30.7 0.2 5.9e-07 29.7 0.1 1.6 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase Myotoxins PF00819.12 EIE77440.1 - 0.0068 16.4 1.0 0.012 15.6 0.1 1.8 2 0 0 2 2 2 1 Myotoxin zf-CCHC PF00098.18 EIE77443.1 - 9.9e-09 34.7 6.0 0.00015 21.5 0.1 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.1 EIE77443.1 - 0.00013 21.5 0.1 0.00033 20.2 0.1 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 EIE77443.1 - 0.006 16.2 4.0 0.56 9.9 0.1 2.4 2 0 0 2 2 2 2 Zinc knuckle NMD3 PF04981.8 EIE77443.1 - 0.012 14.7 3.0 0.013 14.5 2.1 1.3 1 1 0 1 1 1 0 NMD3 family Zn_ribbon_2 PF12674.2 EIE77443.1 - 0.15 12.4 3.0 0.5 10.7 2.0 1.9 1 1 1 2 2 2 0 Putative zinc ribbon domain WD40 PF00400.27 EIE77445.1 - 3.7e-55 181.9 17.4 1.1e-08 34.6 0.2 6.6 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 EIE77445.1 - 3.9e-10 38.4 7.7 0.0088 14.2 0.1 4.9 1 1 4 5 5 5 5 Nucleoporin Nup120/160 PQQ_2 PF13360.1 EIE77445.1 - 0.00099 18.6 0.0 1.1 8.6 0.0 2.5 1 1 1 2 2 2 2 PQQ-like domain Nucleoporin_N PF08801.6 EIE77445.1 - 0.0038 16.0 7.3 0.32 9.6 0.0 3.7 2 1 1 4 4 4 2 Nup133 N terminal like DUF2828 PF11443.3 EIE77446.1 - 0.00086 17.6 2.2 0.00093 17.5 1.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) DUF1632 PF07857.7 EIE77446.1 - 0.14 11.4 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 CEO family (DUF1632) RR_TM4-6 PF06459.7 EIE77446.1 - 0.31 10.9 8.3 0.38 10.6 5.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GCIP PF13324.1 EIE77446.1 - 0.38 9.9 3.9 0.49 9.5 2.4 1.4 1 1 1 2 2 2 0 Grap2 and cyclin-D-interacting GAGA_bind PF06217.7 EIE77446.1 - 2.2 8.1 9.6 2.5 8.0 6.6 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Zip PF02535.17 EIE77446.1 - 3.1 6.7 7.3 3.9 6.3 5.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Sec62 PF03839.11 EIE77446.1 - 5.6 6.3 7.7 10 5.4 5.4 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 AIF_C PF14721.1 EIE77446.1 - 9.1 6.5 8.5 6.5 6.9 4.7 1.6 1 1 1 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF155 PF02582.9 EIE77447.1 - 5.8e-61 205.4 0.7 1e-60 204.6 0.5 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 DUF1059 PF06348.6 EIE77447.1 - 0.4 10.5 1.5 3.1 7.6 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1059) Cation_efflux PF01545.16 EIE77449.1 - 1.7e-29 102.8 12.3 2.1e-29 102.5 8.6 1.1 1 0 0 1 1 1 1 Cation efflux family Nop16 PF09420.5 EIE77450.1 - 1.1e-48 165.4 6.8 1.5e-48 165.0 4.7 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 OHCU_decarbox PF09349.5 EIE77450.1 - 0.13 12.5 0.2 0.13 12.5 0.1 1.9 2 1 0 2 2 2 0 OHCU decarboxylase DUF1293 PF06950.6 EIE77450.1 - 0.14 12.0 0.6 1.7 8.6 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1293) DUF3460 PF11943.3 EIE77450.1 - 0.19 11.8 2.7 0.85 9.7 0.4 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3460) EHN PF06441.7 EIE77450.1 - 0.43 10.5 2.6 0.34 10.8 0.6 1.7 2 0 0 2 2 2 0 Epoxide hydrolase N terminus DUF3940 PF13076.1 EIE77450.1 - 0.86 9.1 4.4 3 7.4 0.9 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3940) MFS_1 PF07690.11 EIE77453.1 - 7.1e-21 74.2 22.6 1.1e-20 73.6 15.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4131 PF13567.1 EIE77453.1 - 6.5 6.1 10.9 0.27 10.6 0.1 2.8 2 2 0 2 2 2 0 Domain of unknown function (DUF4131) Alpha-amylase PF00128.19 EIE77457.1 - 5.2e-59 200.1 0.9 8.6e-45 153.4 0.5 2.5 1 1 1 2 2 2 2 Alpha amylase, catalytic domain DUF1966 PF09260.6 EIE77457.1 - 1.1e-11 44.6 0.9 2.8e-11 43.3 0.6 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) Arrestin_N PF00339.24 EIE77459.1 - 6.2e-07 29.3 0.2 1.8e-05 24.6 0.1 2.1 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Mis14 PF08641.7 EIE77460.1 - 0.042 13.9 1.0 0.089 12.8 0.7 1.5 1 0 0 1 1 1 0 Kinetochore protein Mis14 like Presenilin PF01080.12 EIE77460.1 - 1.3 7.7 4.9 2.2 7.0 3.4 1.4 1 0 0 1 1 1 0 Presenilin Methyltransf_15 PF09445.5 EIE77461.1 - 1.5e-45 154.7 0.0 2.2e-45 154.1 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 EIE77461.1 - 2.8e-11 43.4 0.0 4.1e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 EIE77461.1 - 4.9e-10 39.2 0.0 8.9e-10 38.4 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_31 PF13847.1 EIE77461.1 - 4.5e-09 36.0 0.0 9.6e-09 35.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIE77461.1 - 6.8e-07 29.8 0.0 1.2e-06 29.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EIE77461.1 - 7.5e-07 28.9 0.0 1.3e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.9 EIE77461.1 - 3.3e-05 23.3 0.0 6e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EIE77461.1 - 5.6e-05 23.4 0.0 0.00012 22.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 EIE77461.1 - 9.1e-05 21.9 0.0 0.00017 21.0 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 PrmA PF06325.8 EIE77461.1 - 0.00019 20.6 0.4 0.00046 19.3 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.7 EIE77461.1 - 0.0017 18.8 0.0 0.0059 17.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain RrnaAD PF00398.15 EIE77461.1 - 0.03 13.3 0.0 0.046 12.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_8 PF05148.10 EIE77461.1 - 0.041 13.4 0.0 0.065 12.8 0.0 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_3 PF01596.12 EIE77461.1 - 0.078 12.0 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase Gti1_Pac2 PF09729.4 EIE77463.1 - 1.3e-21 77.2 5.6 7e-13 48.7 0.6 2.2 1 1 1 2 2 2 2 Gti1/Pac2 family HTH_29 PF13551.1 EIE77464.1 - 0.00017 21.6 0.0 0.00025 21.1 0.0 1.2 1 0 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.13 EIE77464.1 - 0.00043 20.2 0.0 0.0014 18.6 0.0 1.8 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.1 EIE77464.1 - 0.0071 15.9 0.0 0.02 14.5 0.0 1.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.1 EIE77464.1 - 0.027 14.4 0.0 0.052 13.5 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_17 PF12728.2 EIE77464.1 - 0.033 14.4 0.1 0.2 11.9 0.0 2.3 2 1 1 3 3 3 0 Helix-turn-helix domain Sigma70_r4 PF04545.11 EIE77464.1 - 0.068 12.4 0.0 1 8.7 0.0 2.2 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_7 PF02796.10 EIE77464.1 - 0.1 12.4 0.2 6.5 6.7 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase Velvet PF11754.3 EIE77466.1 - 2.7e-31 108.7 0.0 4.8e-31 107.9 0.0 1.3 1 0 0 1 1 1 1 Velvet factor FAD_binding_2 PF00890.19 EIE77467.1 - 4.3e-83 279.4 0.6 6.1e-83 278.9 0.1 1.5 2 0 0 2 2 2 1 FAD binding domain Cyt-b5 PF00173.23 EIE77467.1 - 3.8e-23 81.0 0.1 1.1e-22 79.5 0.1 1.9 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.19 EIE77467.1 - 2.1e-11 43.3 0.2 2e-08 33.5 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIE77467.1 - 4.2e-09 36.3 0.3 2.8e-08 33.6 0.1 2.5 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EIE77467.1 - 1.1e-07 31.3 0.0 1.7e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EIE77467.1 - 2.1e-07 31.0 1.2 0.0025 17.7 0.1 3.6 3 1 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIE77467.1 - 5.7e-05 21.7 6.0 0.00032 19.2 0.0 2.6 3 0 0 3 3 3 2 HI0933-like protein Thi4 PF01946.12 EIE77467.1 - 0.00034 19.7 1.2 0.006 15.7 0.0 2.6 3 0 0 3 3 3 1 Thi4 family Pyr_redox_3 PF13738.1 EIE77467.1 - 0.00074 19.6 0.2 0.0027 17.7 0.1 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EIE77467.1 - 0.0016 17.3 0.8 0.008 15.0 0.2 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 EIE77467.1 - 0.014 14.4 0.1 0.023 13.7 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.1 EIE77467.1 - 0.028 14.1 0.0 0.1 12.3 0.0 2.0 1 1 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox PF00070.22 EIE77467.1 - 0.06 13.7 0.0 0.18 12.2 0.0 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EIE77467.1 - 0.089 11.6 0.3 0.16 10.8 0.1 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein GDI PF00996.13 EIE77467.1 - 0.11 10.7 0.1 0.18 10.0 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor Acyltransferase PF01553.16 EIE77468.1 - 1.3e-08 34.3 0.0 7.7e-08 31.8 0.0 2.1 1 1 0 1 1 1 1 Acyltransferase DUF1342 PF07072.6 EIE77468.1 - 0.13 11.8 1.7 0.68 9.5 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1342) Metallophos PF00149.23 EIE77469.1 - 4.6e-20 71.8 0.4 6.8e-20 71.3 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase MRP_L53 PF10780.4 EIE77471.1 - 8.4e-09 35.2 0.1 1.6e-08 34.4 0.1 1.5 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 Paramyx_P_V_C PF03210.8 EIE77471.1 - 0.061 13.1 0.5 0.066 13.0 0.3 1.2 1 0 0 1 1 1 0 Paramyxovirus P/V phosphoprotein C-terminal CENP-N PF05238.8 EIE77472.1 - 9.1e-09 34.8 0.6 6.2e-06 25.5 0.0 2.2 1 1 1 2 2 2 2 Kinetochore protein CHL4 like DsrC PF04358.8 EIE77472.1 - 0.072 13.3 1.5 0.49 10.6 0.1 2.7 2 2 1 3 3 3 0 DsrC like protein HSP20 PF00011.16 EIE77473.1 - 2.3e-18 65.9 0.1 1.5e-16 60.0 0.1 2.1 1 1 0 1 1 1 1 Hsp20/alpha crystallin family CDV3 PF15359.1 EIE77473.1 - 0.032 14.3 0.1 0.041 13.9 0.1 1.2 1 0 0 1 1 1 0 Carnitine deficiency-associated protein 3 GatB_Yqey PF02637.13 EIE77474.1 - 3.1e-38 130.8 0.2 7.2e-38 129.6 0.2 1.5 2 0 0 2 2 2 1 GatB domain GatB_N PF02934.10 EIE77474.1 - 3.1e-16 59.0 0.5 4.9e-16 58.4 0.2 1.4 2 0 0 2 2 2 1 GatB/GatE catalytic domain RasGAP PF00616.14 EIE77475.1 - 8.2e-26 90.8 4.6 1.7e-24 86.6 0.1 3.6 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.1 EIE77475.1 - 3e-18 66.1 0.1 1.1e-17 64.2 0.1 2.1 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain HEAT_2 PF13646.1 EIE77475.1 - 8.2e-08 32.4 3.1 1.5 9.1 0.0 6.7 6 2 0 6 6 6 2 HEAT repeats HEAT PF02985.17 EIE77475.1 - 2.5e-05 23.9 3.5 0.18 11.9 0.0 6.5 7 0 0 7 7 7 1 HEAT repeat DUF4589 PF15252.1 EIE77475.1 - 0.23 11.2 1.5 0.58 9.9 1.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4589) SF3b10 PF07189.6 EIE77477.1 - 4.3e-38 128.9 0.0 4.9e-38 128.8 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) DUF1874 PF08960.5 EIE77477.1 - 0.069 12.9 0.1 0.079 12.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1874) BTB_2 PF02214.17 EIE77478.1 - 0.0057 16.8 0.1 0.1 12.7 0.0 2.7 2 1 0 2 2 2 1 BTB/POZ domain DUF2404 PF10296.4 EIE77480.1 - 1e-21 76.8 0.0 2.1e-21 75.8 0.0 1.5 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) Beta_elim_lyase PF01212.16 EIE77481.1 - 8.7e-63 212.1 0.0 1.8e-62 211.1 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EIE77481.1 - 0.0022 17.0 0.0 0.0037 16.3 0.0 1.5 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family F-box-like PF12937.2 EIE77482.1 - 6.4e-10 38.5 0.8 1.4e-09 37.5 0.6 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIE77482.1 - 0.016 14.8 0.2 0.052 13.2 0.1 1.8 1 0 0 1 1 1 0 F-box domain MFS_1 PF07690.11 EIE77483.1 - 9.8e-26 90.2 57.0 6.2e-18 64.6 21.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Rtt102p PF09510.5 EIE77484.1 - 0.11 12.5 0.1 0.11 12.4 0.0 1.0 1 0 0 1 1 1 0 Rtt102p-like transcription regulator protein SAM_1 PF00536.25 EIE77486.1 - 6.5e-09 35.8 0.1 9.9e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EIE77486.1 - 4.3e-05 23.2 0.0 7.8e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) HMG_box_2 PF09011.5 EIE77486.1 - 0.014 15.6 0.0 0.027 14.8 0.0 1.4 1 0 0 1 1 1 0 HMG-box domain NCD1 PF04904.8 EIE77486.1 - 0.022 14.4 0.0 0.058 13.1 0.0 1.7 1 0 0 1 1 1 0 NAB conserved region 1 (NCD1) Prolamin_like PF05617.6 EIE77486.1 - 0.023 14.8 0.1 0.04 14.0 0.0 1.3 1 0 0 1 1 1 0 Prolamin-like NTP_transf_3 PF12804.2 EIE77486.1 - 0.098 12.7 0.0 0.24 11.4 0.0 1.5 2 0 0 2 2 2 0 MobA-like NTP transferase domain HMG_box PF00505.14 EIE77486.1 - 0.12 12.6 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 HMG (high mobility group) box ETRAMP PF09716.5 EIE77488.1 - 2.8e-05 23.9 0.0 0.00019 21.3 0.0 2.3 1 1 0 1 1 1 1 Malarial early transcribed membrane protein (ETRAMP) DUF4366 PF14283.1 EIE77488.1 - 0.015 14.7 0.0 0.023 14.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) PAP1 PF08601.5 EIE77488.1 - 0.96 9.0 29.9 1.3 8.5 20.7 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 Plasmodium_Vir PF05795.6 EIE77488.1 - 2 7.5 19.7 7.7 5.6 13.7 1.9 1 1 0 1 1 1 0 Plasmodium vivax Vir protein Smr PF01713.16 EIE77489.1 - 3.8e-15 55.8 0.0 6.9e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 Smr domain DUF1771 PF08590.5 EIE77489.1 - 4e-15 55.5 11.9 7.3e-15 54.7 8.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Scytalone_dh PF02982.9 EIE77489.1 - 0.035 13.6 0.1 0.049 13.2 0.1 1.2 1 0 0 1 1 1 0 Scytalone dehydratase Proteasome PF00227.21 EIE77490.1 - 4.6e-47 159.7 0.0 6.1e-47 159.3 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EIE77490.1 - 4.5e-13 48.2 0.1 7.5e-13 47.5 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature CRISPR_Cse1 PF09481.5 EIE77490.1 - 0.12 11.0 0.0 0.16 10.6 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated protein Cse1 (CRISPR_cse1) SWI-SNF_Ssr4 PF08549.5 EIE77491.1 - 3.1e-05 22.5 3.6 0.00037 18.9 0.0 2.1 1 1 1 2 2 2 1 Fungal domain of unknown function (DUF1750) DUF501 PF04417.7 EIE77491.1 - 0.072 12.9 1.0 0.11 12.3 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF501) MRP-L46 PF11788.3 EIE77491.1 - 0.19 12.3 7.6 0.077 13.6 3.4 1.6 2 0 0 2 2 2 0 39S mitochondrial ribosomal protein L46 Cor1 PF04803.7 EIE77491.1 - 0.3 10.8 16.6 0.3 10.8 10.8 1.6 1 1 0 1 1 1 0 Cor1/Xlr/Xmr conserved region Iron_permease PF04120.7 EIE77491.1 - 0.3 10.6 2.8 0.52 9.9 2.0 1.3 1 0 0 1 1 1 0 Low affinity iron permease 4HB_MCP_1 PF12729.2 EIE77491.1 - 0.47 9.7 9.5 0.76 9.1 6.6 1.2 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction PIN_2 PF10130.4 EIE77491.1 - 0.71 9.9 3.5 1.2 9.1 2.1 1.6 1 1 0 1 1 1 0 PIN domain IncA PF04156.9 EIE77491.1 - 0.72 9.4 9.1 0.88 9.1 6.3 1.2 1 0 0 1 1 1 0 IncA protein Pkinase PF00069.20 EIE77492.1 - 1.7e-66 224.0 0.0 2.9e-66 223.2 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE77492.1 - 7.8e-30 103.8 0.1 8.8e-29 100.3 0.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE77492.1 - 0.01 14.8 0.0 3.9 6.3 0.0 2.7 3 0 0 3 3 3 0 Kinase-like WD40 PF00400.27 EIE77493.1 - 3.5e-15 55.2 3.0 0.35 10.8 0.1 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat PPR_2 PF13041.1 EIE77494.1 - 6e-16 58.1 0.3 0.0019 18.1 0.0 5.3 5 1 0 5 5 5 4 PPR repeat family PPR_3 PF13812.1 EIE77494.1 - 5.3e-12 45.0 1.2 0.094 13.0 0.0 5.4 5 0 0 5 5 5 3 Pentatricopeptide repeat domain PPR PF01535.15 EIE77494.1 - 2.9e-07 29.9 0.1 0.081 12.9 0.0 4.7 4 0 0 4 4 4 2 PPR repeat TPR_19 PF14559.1 EIE77494.1 - 0.017 15.4 1.1 11 6.4 0.0 3.4 3 1 0 4 4 4 0 Tetratricopeptide repeat SPO22 PF08631.5 EIE77494.1 - 0.025 13.6 0.1 0.025 13.6 0.1 2.2 3 0 0 3 3 3 0 Meiosis protein SPO22/ZIP4 like T_Ag_DNA_bind PF02217.11 EIE77494.1 - 0.031 14.6 0.2 0.031 14.6 0.2 2.6 3 0 0 3 3 3 0 Origin of replication binding protein TPR_14 PF13428.1 EIE77494.1 - 0.035 14.7 0.1 43 5.1 0.0 3.9 4 1 1 5 5 5 0 Tetratricopeptide repeat Cullin_binding PF03556.10 EIE77494.1 - 0.079 13.1 5.5 3.7 7.7 0.3 2.7 2 2 0 2 2 2 0 Cullin binding PPR_1 PF12854.2 EIE77494.1 - 0.14 11.6 0.0 4.2 6.9 0.0 3.3 4 0 0 4 4 4 0 PPR repeat TrkH PF02386.11 EIE77495.1 - 3.3e-38 131.1 8.4 7e-38 130.1 3.0 2.1 2 0 0 2 2 2 2 Cation transport protein Parvo_coat PF00740.13 EIE77495.1 - 0.033 13.1 9.8 0.041 12.8 6.8 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 Asp PF00026.18 EIE77497.1 - 1.3e-95 320.2 4.0 1.6e-95 319.9 2.8 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIE77497.1 - 1.9e-06 27.9 1.1 8.4e-05 22.5 0.2 3.1 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EIE77497.1 - 4e-05 24.0 2.3 0.14 12.6 0.0 3.1 3 1 0 3 3 3 2 Aspartyl protease TAXi_C PF14541.1 EIE77497.1 - 0.00018 21.1 0.1 0.004 16.7 0.1 2.4 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Big_1 PF02369.11 EIE77497.1 - 0.0045 16.8 0.4 0.014 15.2 0.1 1.9 2 0 0 2 2 2 1 Bacterial Ig-like domain (group 1) Sec63 PF02889.11 EIE77498.1 - 3.9e-212 703.0 1.8 2.2e-113 378.6 0.3 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 EIE77498.1 - 2.4e-55 186.6 0.7 3.3e-29 101.5 0.0 3.1 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.10 EIE77498.1 - 8.9e-21 74.5 0.4 6.6e-09 35.8 0.0 3.2 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EIE77498.1 - 5.5e-11 42.1 0.0 2.3e-09 36.9 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EIE77498.1 - 1.3e-06 28.5 0.8 0.038 14.1 0.1 3.6 3 1 0 3 3 3 2 AAA domain AAA_19 PF13245.1 EIE77498.1 - 0.00031 20.4 0.0 0.084 12.6 0.0 3.2 2 0 0 2 2 2 1 Part of AAA domain PhoH PF02562.11 EIE77498.1 - 0.00054 19.2 0.0 0.071 12.3 0.0 2.6 2 0 0 2 2 2 1 PhoH-like protein AAA_23 PF13476.1 EIE77498.1 - 0.00085 19.7 9.1 0.0054 17.0 0.0 4.1 4 0 0 4 4 4 1 AAA domain AAA_10 PF12846.2 EIE77498.1 - 0.00099 18.6 0.4 2.1 7.6 0.0 4.5 5 0 0 5 5 5 1 AAA-like domain T2SE PF00437.15 EIE77498.1 - 0.001 18.0 0.0 0.17 10.7 0.0 3.0 4 0 0 4 4 4 1 Type II/IV secretion system protein IstB_IS21 PF01695.12 EIE77498.1 - 0.013 14.9 0.2 2.9 7.2 0.0 3.2 4 0 0 4 4 4 0 IstB-like ATP binding protein zf-RVT PF13966.1 EIE77499.1 - 8.7e-07 29.1 0.6 8.7e-07 29.1 0.4 1.8 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase Chromo PF00385.19 EIE77500.1 - 1.4e-07 31.0 2.7 2.2e-07 30.4 0.1 2.4 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain DUF2870 PF11069.3 EIE77500.1 - 0.039 13.9 0.4 0.06 13.3 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2870) zf-C4pol PF14260.1 EIE77501.1 - 0.035 14.1 4.6 0.47 10.4 3.2 2.0 1 1 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta DZR PF12773.2 EIE77501.1 - 0.16 11.8 10.0 0.72 9.7 2.1 2.3 1 1 0 2 2 2 0 Double zinc ribbon A2L_zn_ribbon PF08792.5 EIE77501.1 - 0.46 10.0 7.8 18 4.9 0.1 3.1 3 0 0 3 3 3 0 A2L zinc ribbon domain zf-ribbon_3 PF13248.1 EIE77501.1 - 0.74 9.1 7.7 0.28 10.4 1.6 2.5 1 1 1 2 2 2 0 zinc-ribbon domain RRN7 PF11781.3 EIE77501.1 - 0.78 9.2 8.3 5.9 6.4 0.3 3.1 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 GFA PF04828.9 EIE77501.1 - 0.88 9.5 7.8 0.11 12.4 1.1 2.0 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme HypA PF01155.14 EIE77501.1 - 4.4 7.0 6.4 1.6 8.4 1.1 1.9 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zinc_ribbon_2 PF13240.1 EIE77501.1 - 5 6.7 9.5 3.1 7.3 0.1 2.9 2 1 0 2 2 2 0 zinc-ribbon domain NifW PF03206.9 EIE77502.1 - 0.055 13.5 0.2 0.077 13.1 0.1 1.2 1 0 0 1 1 1 0 Nitrogen fixation protein NifW PID_2 PF14719.1 EIE77502.1 - 0.075 12.6 0.1 0.086 12.4 0.1 1.1 1 0 0 1 1 1 0 Phosphotyrosine interaction domain (PTB/PID) DUF2482 PF10655.4 EIE77502.1 - 0.1 12.6 0.1 0.26 11.3 0.0 1.7 2 0 0 2 2 2 0 Hypothetical protein of unknown function (DUF2482) Ras PF00071.17 EIE77503.1 - 3.4e-16 59.0 0.2 4.8e-16 58.5 0.1 1.2 1 0 0 1 1 1 1 Ras family FeoB_N PF02421.13 EIE77503.1 - 0.04 13.2 0.2 0.064 12.5 0.1 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B Arf PF00025.16 EIE77503.1 - 0.071 12.3 0.1 0.09 12.0 0.1 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family Cellulase-like PF12876.2 EIE77503.1 - 0.091 13.2 0.1 0.16 12.4 0.1 1.6 1 1 0 1 1 1 0 Sugar-binding cellulase-like Chrome_Resist PF09828.4 EIE77504.1 - 0.0042 17.2 0.1 0.038 14.1 0.0 2.0 2 0 0 2 2 2 1 Chromate resistance exported protein Dyp_perox PF04261.7 EIE77504.1 - 0.058 12.1 0.0 0.089 11.5 0.0 1.2 1 0 0 1 1 1 0 Dyp-type peroxidase family WD40 PF00400.27 EIE77505.1 - 4.3e-16 58.1 14.7 0.00073 19.3 0.2 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 EIE77505.1 - 3e-06 25.6 4.3 0.034 12.2 0.1 3.3 1 1 2 3 3 3 3 Nucleoporin Nup120/160 PHF5 PF03660.9 EIE77508.1 - 6.5e-49 164.4 6.1 7.3e-49 164.3 4.2 1.0 1 0 0 1 1 1 1 PHF5-like protein DUF2039 PF10217.4 EIE77508.1 - 0.24 11.4 6.4 0.6 10.1 0.2 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2039) PHD PF00628.24 EIE77508.1 - 0.89 9.2 8.9 0.68 9.6 4.5 2.2 2 1 0 2 2 2 0 PHD-finger zf-C3HC4_3 PF13920.1 EIE77508.1 - 6.9 6.4 10.7 1.4 8.6 2.7 2.8 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RanBP PF00641.13 EIE77508.1 - 7.2 5.8 7.0 22 4.2 0.0 3.2 4 0 0 4 4 4 0 Zn-finger in Ran binding protein and others bZIP_1 PF00170.16 EIE77509.1 - 2.7e-09 36.8 6.2 6e-09 35.7 4.3 1.6 1 0 0 1 1 1 1 bZIP transcription factor Aft1_OSA PF11785.3 EIE77509.1 - 3e-06 27.6 2.7 3.5e-06 27.4 0.1 2.4 2 0 0 2 2 2 1 Aft1 osmotic stress response (OSM) domain bZIP_2 PF07716.10 EIE77509.1 - 9e-06 25.4 5.2 2e-05 24.2 3.6 1.6 1 0 0 1 1 1 1 Basic region leucine zipper Aft1_HRA PF11786.3 EIE77509.1 - 0.00015 21.9 0.1 0.00015 21.9 0.0 2.1 2 1 0 2 2 2 1 Aft1 HRA domain HALZ PF02183.13 EIE77509.1 - 0.0038 16.9 3.0 0.0074 15.9 2.1 1.4 1 0 0 1 1 1 1 Homeobox associated leucine zipper DivIC PF04977.10 EIE77509.1 - 0.15 11.5 3.0 0.31 10.5 2.0 1.5 1 0 0 1 1 1 0 Septum formation initiator bZIP_Maf PF03131.12 EIE77509.1 - 0.55 10.5 10.2 0.076 13.3 1.8 2.4 1 1 1 2 2 2 0 bZIP Maf transcription factor SE PF08491.5 EIE77511.1 - 1.1e-91 306.5 0.1 1.3e-80 270.1 0.0 2.4 2 1 1 3 3 3 2 Squalene epoxidase FAD_binding_3 PF01494.14 EIE77511.1 - 8.7e-11 41.4 0.0 2.3e-07 30.2 0.0 2.6 1 1 1 2 2 2 2 FAD binding domain DAO PF01266.19 EIE77511.1 - 1.8e-08 33.6 0.0 4.9e-05 22.4 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase GIDA PF01134.17 EIE77511.1 - 7.9e-05 21.6 0.3 0.00017 20.5 0.2 1.5 1 1 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.12 EIE77511.1 - 8e-05 21.8 0.0 0.00016 20.8 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 EIE77511.1 - 0.0012 19.2 0.0 0.0028 18.0 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIE77511.1 - 0.0014 18.6 0.4 0.003 17.5 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EIE77511.1 - 0.0022 17.9 0.0 0.0032 17.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EIE77511.1 - 0.0026 16.6 1.1 0.053 12.3 0.3 2.1 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 EIE77511.1 - 0.0077 15.3 0.4 0.011 14.8 0.3 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Shikimate_DH PF01488.15 EIE77511.1 - 0.027 14.5 0.0 0.052 13.6 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 EIE77511.1 - 0.049 13.2 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 EIE77511.1 - 0.14 10.6 0.0 0.2 10.0 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Cactin_mid PF10312.4 EIE77511.1 - 0.18 11.0 0.0 0.29 10.3 0.0 1.4 1 0 0 1 1 1 0 Conserved mid region of cactin RVT_1 PF00078.22 EIE77517.1 - 1.2e-15 57.4 0.2 3e-15 56.1 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 EIE77517.1 - 6.8e-08 32.8 0.1 1.8e-07 31.5 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 EIE77517.1 - 4.2e-07 29.7 0.1 3.8e-06 26.7 0.0 2.6 2 1 0 2 2 2 1 Retroviral aspartyl protease Retrotrans_gag PF03732.12 EIE77517.1 - 8.3e-05 22.5 1.0 0.00081 19.4 0.0 3.1 3 0 0 3 3 3 1 Retrotransposon gag protein gag-asp_proteas PF13975.1 EIE77517.1 - 0.00036 20.3 0.0 0.00088 19.0 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.5 EIE77517.1 - 0.016 14.8 0.5 0.043 13.3 0.1 1.9 2 0 0 2 2 2 0 Aspartyl protease PMC2NT PF08066.7 EIE77517.1 - 0.034 14.4 3.1 5.6 7.3 0.0 3.4 3 0 0 3 3 3 0 PMC2NT (NUC016) domain Peptidase_M3_N PF08439.5 EIE77517.1 - 0.047 13.7 1.4 0.12 12.4 0.2 2.3 2 0 0 2 2 1 0 Oligopeptidase F RVP_2 PF08284.6 EIE77517.1 - 0.059 13.3 0.1 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF3479 PF11965.3 EIE77517.1 - 0.082 12.6 1.1 0.14 11.9 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3479) V-SNARE PF05008.10 EIE77517.1 - 1.2 9.3 10.0 0.45 10.7 4.1 2.6 2 0 0 2 2 1 0 Vesicle transport v-SNARE protein N-terminus FlxA PF14282.1 EIE77517.1 - 1.5 8.7 9.0 1.5 8.8 3.7 2.9 2 1 0 2 2 2 0 FlxA-like protein IncA PF04156.9 EIE77517.1 - 2.9 7.4 6.8 7.7 6.0 4.7 1.7 1 0 0 1 1 1 0 IncA protein rve PF00665.21 EIE77518.1 - 1.2e-17 64.1 0.0 2.6e-17 63.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 EIE77518.1 - 2e-09 36.9 0.5 4.3e-09 35.9 0.3 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 EIE77518.1 - 0.0097 15.5 0.1 0.032 13.9 0.1 1.9 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain DDE_3 PF13358.1 EIE77520.1 - 7.4e-19 67.9 0.0 8.8e-19 67.6 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Leader_Erm PF08253.6 EIE77522.1 - 0.33 10.4 0.3 0.33 10.4 0.2 2.1 2 0 0 2 2 2 0 Erm Leader peptide DDE_3 PF13358.1 EIE77523.1 - 1.1e-20 73.8 0.4 2.4e-20 72.7 0.3 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE77523.1 - 3.3e-10 39.8 0.9 3.3e-10 39.8 0.6 2.4 2 0 0 2 2 2 1 Transposase HTH_38 PF13936.1 EIE77523.1 - 0.00019 20.8 0.1 0.00052 19.5 0.1 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain Mitovir_RNA_pol PF05919.6 EIE77523.1 - 0.0034 16.4 0.3 0.005 15.8 0.2 1.2 1 0 0 1 1 1 1 Mitovirus RNA-dependent RNA polymerase HTH_23 PF13384.1 EIE77523.1 - 0.0043 16.6 0.6 0.014 14.9 0.0 2.1 2 0 0 2 2 2 1 Homeodomain-like domain MarR PF01047.17 EIE77523.1 - 0.006 16.2 0.1 0.28 10.9 0.0 2.6 3 0 0 3 3 3 1 MarR family Sigma54_DBD PF04552.8 EIE77523.1 - 0.032 13.7 0.1 0.11 11.9 0.0 1.9 1 1 0 1 1 1 0 Sigma-54, DNA binding domain HTH_Crp_2 PF13545.1 EIE77523.1 - 0.045 13.5 0.1 0.97 9.2 0.0 2.3 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain Phage_CII PF05269.6 EIE77523.1 - 0.082 12.9 0.3 0.29 11.1 0.0 2.0 2 1 0 2 2 2 0 Bacteriophage CII protein HTH_6 PF01418.12 EIE77523.1 - 0.1 12.3 0.0 0.26 11.0 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family HTH_32 PF13565.1 EIE77523.1 - 0.12 13.2 1.9 37 5.2 0.0 3.4 2 1 1 3 3 3 0 Homeodomain-like domain LacI PF00356.16 EIE77523.1 - 0.15 11.6 0.4 0.56 9.8 0.0 2.1 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family TetR_N PF00440.18 EIE77523.1 - 0.17 11.5 0.2 0.34 10.5 0.2 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family TrmB PF01978.14 EIE77523.1 - 0.21 11.3 1.2 2.7 7.7 0.0 2.8 2 1 1 3 3 3 0 Sugar-specific transcriptional regulator TrmB FAM222A PF15258.1 EIE77524.1 - 0.0051 16.0 6.4 0.0062 15.8 4.4 1.1 1 0 0 1 1 1 1 Protein family of FAM222A Med15 PF09606.5 EIE77524.1 - 0.0071 14.6 12.0 0.0092 14.2 8.3 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Mod_r PF07200.8 EIE77525.1 - 0.00026 20.9 0.1 0.00051 19.9 0.1 1.4 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Matrilin_ccoil PF10393.4 EIE77525.1 - 0.023 14.0 0.2 0.05 12.9 0.2 1.5 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin Reo_sigmaC PF04582.7 EIE77525.1 - 0.068 12.3 1.1 0.1 11.7 0.8 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein TMF_DNA_bd PF12329.3 EIE77525.1 - 0.14 11.9 4.0 1.5 8.6 1.4 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding LacI PF00356.16 EIE77525.1 - 0.39 10.3 2.5 1.2 8.7 0.0 2.7 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family Leader_Erm PF08253.6 EIE77526.1 - 0.33 10.4 0.3 0.33 10.4 0.2 2.0 2 0 0 2 2 2 0 Erm Leader peptide DUF1203 PF06718.6 EIE77527.1 - 0.085 12.6 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1203) VIT1 PF01988.14 EIE77527.1 - 3.8 6.9 4.9 7.1 6.0 3.4 1.5 1 1 0 1 1 1 0 VIT family Transposase_21 PF02992.9 EIE77528.1 - 1.2e-15 57.2 0.0 1.7e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 Transposase family tnp2 DUF1258 PF06869.7 EIE77528.1 - 0.0028 16.7 0.0 0.005 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) Evr1_Alr PF04777.8 EIE77528.1 - 0.12 12.2 0.7 2.1 8.3 0.1 2.3 2 0 0 2 2 2 0 Erv1 / Alr family zf-C2H2_4 PF13894.1 EIE77528.1 - 0.68 10.4 2.5 29 5.3 0.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger DDE_Tnp_IS1595 PF12762.2 EIE77529.1 - 3.1e-05 23.8 0.0 4.4e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 ISXO2-like transposase domain DDE_Tnp_IS1595 PF12762.2 EIE77530.1 - 1.3e-05 25.0 0.0 1.7e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 ISXO2-like transposase domain rve PF00665.21 EIE77531.1 - 1.6e-22 79.8 0.0 3.8e-22 78.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE77531.1 - 1.3e-15 57.3 0.1 2.3e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE77531.1 - 9.4e-08 31.6 0.2 1.7e-07 30.7 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 EIE77531.1 - 0.00039 19.7 1.6 0.0012 18.1 1.1 2.0 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Retrotrans_gag PF03732.12 EIE77531.1 - 0.0064 16.5 0.1 0.021 14.8 0.1 1.9 1 0 0 1 1 1 1 Retrotransposon gag protein Pex26 PF07163.7 EIE77533.1 - 0.0023 16.9 0.1 0.051 12.4 0.1 2.1 1 1 0 1 1 1 1 Pex26 protein Abhydrolase_6 PF12697.2 EIE77534.1 - 0.00097 19.0 0.0 0.0022 17.8 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIE77534.1 - 0.16 11.6 0.0 0.41 10.3 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family Spot_14 PF07084.7 EIE77535.1 - 1.2 8.9 7.0 1.3 8.8 4.9 1.0 1 0 0 1 1 1 0 Thyroid hormone-inducible hepatic protein Spot 14 Vfa1 PF08432.5 EIE77535.1 - 4.5 7.2 16.9 4.5 7.2 11.7 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Peptidase_S49_N PF08496.5 EIE77535.1 - 5.2 6.8 6.2 5.6 6.7 4.3 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Aa_trans PF01490.13 EIE77537.1 - 5.2e-44 150.3 20.4 7.6e-44 149.8 14.1 1.3 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein MENTAL PF10457.4 EIE77537.1 - 6.4 6.3 8.1 16 5.0 0.0 3.0 3 0 0 3 3 3 0 Cholesterol-capturing domain 2TM PF13239.1 EIE77537.1 - 7.1 6.7 13.1 0.84 9.7 0.6 3.2 3 0 0 3 3 3 0 2TM domain Pex24p PF06398.6 EIE77538.1 - 2.8e-13 49.3 7.9 1.1e-12 47.4 5.2 1.9 1 1 0 1 1 1 1 Integral peroxisomal membrane peroxin C1_1 PF00130.17 EIE77538.1 - 0.00014 21.5 0.2 0.00024 20.7 0.1 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Myf5 PF12232.3 EIE77538.1 - 2.3 8.8 6.2 0.7 10.5 1.9 1.9 2 0 0 2 2 2 0 Myogenic determination factor 5 RA PF00788.18 EIE77539.1 - 6.3e-08 32.9 0.2 6.6e-05 23.3 0.1 2.8 2 0 0 2 2 2 2 Ras association (RalGDS/AF-6) domain SH3_1 PF00018.23 EIE77539.1 - 0.0013 18.0 0.1 0.0044 16.3 0.0 2.0 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EIE77539.1 - 0.028 14.0 0.0 0.054 13.0 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain Fzo_mitofusin PF04799.8 EIE77539.1 - 0.076 12.3 0.1 0.076 12.3 0.1 2.1 3 0 0 3 3 3 0 fzo-like conserved region DNA_pack_N PF02500.10 EIE77539.1 - 4.6 6.6 10.0 0.82 9.1 0.2 2.5 2 1 1 3 3 3 0 Probable DNA packing protein, N-terminus PRP1_N PF06424.7 EIE77540.1 - 9.8e-50 168.3 2.9 2.2e-49 167.2 2.0 1.6 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 EIE77540.1 - 4.2e-37 123.2 12.5 0.028 15.0 0.0 14.7 5 4 10 15 15 15 11 Tetratricopeptide repeat TPR_19 PF14559.1 EIE77540.1 - 2e-25 88.9 7.1 3.3e-06 27.3 0.1 9.8 7 3 3 10 10 10 5 Tetratricopeptide repeat TPR_16 PF13432.1 EIE77540.1 - 3.5e-25 88.0 1.2 0.00021 21.8 0.1 8.1 8 1 0 8 8 8 4 Tetratricopeptide repeat TPR_11 PF13414.1 EIE77540.1 - 7e-19 67.2 6.6 1.4e-06 27.8 0.0 8.5 5 3 3 9 9 9 3 TPR repeat TPR_2 PF07719.12 EIE77540.1 - 2e-17 61.6 7.1 0.044 13.7 0.0 10.9 13 0 0 13 13 13 3 Tetratricopeptide repeat TPR_8 PF13181.1 EIE77540.1 - 1.6e-15 55.6 1.5 0.027 14.2 0.0 7.8 9 0 0 9 9 7 3 Tetratricopeptide repeat TPR_17 PF13431.1 EIE77540.1 - 1.4e-10 40.5 4.4 0.13 12.5 0.0 9.9 11 1 1 12 12 12 1 Tetratricopeptide repeat TPR_1 PF00515.23 EIE77540.1 - 1.8e-10 39.9 0.7 0.15 11.7 0.0 5.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_6 PF13174.1 EIE77540.1 - 2.4e-10 40.1 2.3 0.75 10.3 0.0 8.6 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_12 PF13424.1 EIE77540.1 - 2.6e-08 33.6 5.8 0.17 11.8 0.0 7.5 5 2 1 6 6 6 3 Tetratricopeptide repeat DUF3808 PF10300.4 EIE77540.1 - 9.3e-05 21.1 0.5 0.34 9.4 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF3808) TPR_21 PF09976.4 EIE77540.1 - 0.00026 20.9 6.5 0.029 14.3 0.2 4.7 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 EIE77540.1 - 0.0041 16.8 0.5 18 5.4 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat NARP1 PF12569.3 EIE77540.1 - 0.013 14.2 11.0 0.13 10.9 0.0 4.7 4 1 1 6 6 6 0 NMDA receptor-regulated protein 1 Fer4_15 PF13459.1 EIE77540.1 - 0.027 15.0 0.1 12 6.5 0.0 4.0 4 0 0 4 4 3 0 4Fe-4S single cluster domain Kelch_4 PF13418.1 EIE77541.1 - 5.3e-09 35.7 0.0 8.5e-08 31.8 0.0 2.3 2 1 0 2 2 2 1 Galactose oxidase, central domain Kelch_6 PF13964.1 EIE77541.1 - 1.7e-06 27.9 0.0 0.0023 18.0 0.0 2.4 2 0 0 2 2 2 2 Kelch motif Kelch_3 PF13415.1 EIE77541.1 - 3.7e-06 26.9 0.3 0.00022 21.2 0.0 3.0 3 1 0 3 3 3 1 Galactose oxidase, central domain Kelch_5 PF13854.1 EIE77541.1 - 0.00011 22.1 0.0 0.0078 16.1 0.0 2.5 2 0 0 2 2 2 1 Kelch motif VSP PF03302.8 EIE77541.1 - 0.018 13.7 0.9 0.024 13.2 0.6 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein SKG6 PF08693.5 EIE77541.1 - 0.055 12.7 3.9 0.099 11.9 2.7 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF2648 PF10855.3 EIE77541.1 - 0.88 9.0 3.0 1.5 8.3 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2648) Na_sulph_symp PF00939.14 EIE77542.1 - 1.5e-52 179.0 0.1 1.7e-52 178.8 0.1 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region ALMT PF11744.3 EIE77543.1 - 8.4e-19 67.4 6.1 9.8e-15 54.1 0.9 2.4 2 0 0 2 2 2 2 Aluminium activated malate transporter FUSC_2 PF13515.1 EIE77543.1 - 6.8e-15 55.1 9.7 6.8e-15 55.1 6.7 2.5 2 0 0 2 2 2 1 Fusaric acid resistance protein-like DUF2421 PF10334.4 EIE77543.1 - 1.3e-10 41.3 2.6 3.4e-10 39.9 0.7 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF2421) DUF2422 PF10337.4 EIE77543.1 - 1.5e-09 37.1 0.0 1.5e-09 37.1 0.0 1.9 3 0 0 3 3 3 1 Protein of unknown function (DUF2422) FUSC PF04632.7 EIE77543.1 - 2.4e-09 36.2 11.7 3.6e-06 25.7 5.0 2.5 3 0 0 3 3 3 2 Fusaric acid resistance protein family DUF939 PF06081.6 EIE77543.1 - 7.8 6.3 10.7 6.5 6.6 3.5 2.7 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF939) HLH PF00010.21 EIE77544.1 - 3.4e-13 49.0 2.4 3.5e-13 49.0 0.3 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain ATG16 PF08614.6 EIE77544.1 - 0.00047 20.0 19.3 0.0025 17.6 13.4 2.0 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) TSC22 PF01166.13 EIE77544.1 - 0.0052 16.7 2.4 0.0052 16.7 1.7 3.2 1 1 1 2 2 2 1 TSC-22/dip/bun family DivIC PF04977.10 EIE77544.1 - 0.019 14.4 4.8 0.019 14.4 3.3 2.4 2 1 0 2 2 2 0 Septum formation initiator AKNA PF12443.3 EIE77544.1 - 0.022 14.7 3.1 0.022 14.7 2.1 2.0 2 1 0 2 2 1 0 AT-hook-containing transcription factor DUF16 PF01519.11 EIE77544.1 - 0.023 14.9 5.4 0.023 14.9 3.7 1.7 2 0 0 2 2 1 0 Protein of unknown function DUF16 DUF972 PF06156.8 EIE77544.1 - 0.033 14.5 3.4 0.033 14.5 2.4 2.5 2 2 1 3 3 3 0 Protein of unknown function (DUF972) DUF3828 PF12883.2 EIE77544.1 - 0.033 14.0 0.5 0.074 12.9 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3828) Spc7 PF08317.6 EIE77544.1 - 0.051 12.2 12.0 0.018 13.7 6.5 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein Macoilin PF09726.4 EIE77544.1 - 0.064 11.5 8.8 0.077 11.2 6.1 1.2 1 0 0 1 1 1 0 Transmembrane protein DNA_primase_lrg PF04104.9 EIE77544.1 - 0.075 12.2 3.6 0.13 11.4 1.7 1.8 1 1 1 2 2 2 0 Eukaryotic and archaeal DNA primase, large subunit H-kinase_dim PF02895.9 EIE77544.1 - 0.077 13.3 2.8 0.27 11.6 1.9 1.9 1 0 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain FlaC_arch PF05377.6 EIE77544.1 - 0.08 12.8 3.8 2.1 8.3 1.1 2.7 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) V_ATPase_I PF01496.14 EIE77544.1 - 0.1 10.4 5.6 0.12 10.2 3.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NPV_P10 PF05531.7 EIE77544.1 - 0.12 12.6 3.6 0.098 12.9 0.9 2.1 2 0 0 2 2 1 0 Nucleopolyhedrovirus P10 protein DUF2205 PF10224.4 EIE77544.1 - 0.12 11.9 4.9 0.35 10.4 3.4 1.9 1 1 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) DUF3573 PF12097.3 EIE77544.1 - 0.14 10.7 1.5 0.21 10.1 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DUF948 PF06103.6 EIE77544.1 - 0.22 11.3 2.1 0.58 10.0 1.4 1.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) TMF_DNA_bd PF12329.3 EIE77544.1 - 0.28 11.0 13.0 0.89 9.4 9.0 2.0 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding HALZ PF02183.13 EIE77544.1 - 0.32 10.7 5.9 0.81 9.4 2.7 2.7 1 1 1 2 2 2 0 Homeobox associated leucine zipper DUF2443 PF10398.4 EIE77544.1 - 0.38 10.5 2.9 0.47 10.2 0.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2443) Baculo_PEP_C PF04513.7 EIE77544.1 - 0.39 10.5 4.9 0.81 9.5 3.4 1.5 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus bZIP_1 PF00170.16 EIE77544.1 - 0.58 10.1 8.8 0.18 11.7 2.2 2.6 1 1 1 2 2 2 0 bZIP transcription factor CorA PF01544.13 EIE77544.1 - 0.66 8.9 5.0 1 8.2 3.4 1.4 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF904 PF06005.7 EIE77544.1 - 0.7 10.2 15.4 0.051 13.8 5.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF904) TBPIP PF07106.8 EIE77544.1 - 1 8.9 13.0 0.1 12.1 5.6 1.7 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Fib_alpha PF08702.5 EIE77544.1 - 1.2 9.2 9.4 0.091 12.8 2.9 1.8 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Ax_dynein_light PF10211.4 EIE77544.1 - 1.5 8.6 13.0 0.074 12.8 5.1 1.7 2 0 0 2 2 2 0 Axonemal dynein light chain Cluap1 PF10234.4 EIE77544.1 - 1.8 7.7 11.1 0.13 11.3 4.5 1.5 2 0 0 2 2 2 0 Clusterin-associated protein-1 DUF3373 PF11853.3 EIE77544.1 - 1.9 6.9 4.1 2.5 6.5 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) DUF947 PF06102.7 EIE77544.1 - 3.8 7.2 11.4 13 5.5 7.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF947) Atg14 PF10186.4 EIE77544.1 - 5 5.9 15.3 11 4.8 10.6 1.7 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3450 PF11932.3 EIE77544.1 - 5.2 6.2 10.7 0.11 11.7 2.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) IncA PF04156.9 EIE77544.1 - 6.2 6.3 16.9 0.29 10.6 7.4 1.8 1 1 0 2 2 2 0 IncA protein Spc24 PF08286.6 EIE77544.1 - 9 6.0 11.6 1.2 8.8 2.9 2.5 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Tropomyosin_1 PF12718.2 EIE77545.1 - 3e-11 43.3 6.1 3.2e-11 43.2 4.2 1.0 1 0 0 1 1 1 1 Tropomyosin like Filament PF00038.16 EIE77545.1 - 0.0036 16.8 5.3 0.004 16.6 3.7 1.0 1 0 0 1 1 1 1 Intermediate filament protein Tropomyosin PF00261.15 EIE77545.1 - 0.01 14.9 6.7 0.018 14.1 4.3 1.6 1 1 0 1 1 1 0 Tropomyosin DUF1741 PF08427.5 EIE77545.1 - 0.016 14.6 1.7 0.017 14.6 1.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1741) TMF_DNA_bd PF12329.3 EIE77545.1 - 0.034 13.9 10.6 0.044 13.5 7.3 1.1 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Phage_lysis PF03245.8 EIE77545.1 - 0.036 14.0 3.4 0.04 13.8 2.3 1.0 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein ADIP PF11559.3 EIE77545.1 - 0.15 11.9 6.8 0.18 11.6 4.7 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding APG6 PF04111.7 EIE77545.1 - 0.26 10.2 6.4 0.29 10.1 4.5 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4140 PF13600.1 EIE77545.1 - 0.28 11.6 1.8 0.34 11.3 1.3 1.2 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF2570 PF10828.3 EIE77545.1 - 0.31 10.6 4.1 0.34 10.5 2.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) DASH_Hsk3 PF08227.6 EIE77545.1 - 0.39 10.9 4.0 0.27 11.4 1.3 1.8 3 0 0 3 3 3 0 DASH complex subunit Hsk3 like HalX PF08663.5 EIE77545.1 - 0.78 9.7 6.3 1.3 9.0 0.6 2.1 1 1 1 2 2 2 0 HalX domain CCDC-167 PF15188.1 EIE77545.1 - 0.96 9.4 5.0 11 6.0 0.2 2.1 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 Atg14 PF10186.4 EIE77545.1 - 1.2 8.0 5.6 1.2 8.0 3.9 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Spc24 PF08286.6 EIE77545.1 - 1.2 8.8 6.4 1.1 8.9 2.5 1.8 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Prefoldin_2 PF01920.15 EIE77545.1 - 2.2 8.0 9.5 8.9 6.1 6.6 1.8 1 1 0 1 1 1 0 Prefoldin subunit Pkinase PF00069.20 EIE77546.1 - 1.3e-62 211.3 0.0 2.3e-62 210.5 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE77546.1 - 1.2e-34 119.5 0.0 6.7e-34 117.1 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE77546.1 - 8.4e-09 34.7 0.0 1.8e-08 33.7 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EIE77546.1 - 0.0021 17.8 0.0 0.31 10.7 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Endonuc-EcoRV PF09233.6 EIE77547.1 - 0.027 13.8 0.4 0.071 12.4 0.1 1.7 1 1 1 2 2 2 0 Restriction endonuclease EcoRV DUF2407 PF10302.4 EIE77548.1 - 1.4e-08 34.8 2.2 3.2e-08 33.6 1.5 1.6 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.18 EIE77548.1 - 1.3e-06 27.6 0.1 1.3e-06 27.6 0.1 2.0 1 1 1 2 2 2 1 Ubiquitin family Rad60-SLD_2 PF13881.1 EIE77548.1 - 5e-05 23.1 3.7 0.00022 21.1 2.6 2.2 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Med15 PF09606.5 EIE77548.1 - 0.0013 17.0 30.1 0.0018 16.5 20.9 1.3 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal TFIIA PF03153.8 EIE77548.1 - 0.0033 17.3 21.0 0.0053 16.7 14.6 1.4 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Herpes_TAF50 PF03326.8 EIE77548.1 - 0.016 14.2 25.3 0.022 13.7 17.6 1.3 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) DUF3043 PF11241.3 EIE77548.1 - 0.028 13.9 4.7 2.6 7.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) DUF605 PF04652.11 EIE77548.1 - 0.077 12.3 19.6 0.13 11.6 13.6 1.3 1 0 0 1 1 1 0 Vta1 like Suf PF05843.9 EIE77548.1 - 0.08 12.6 17.5 0.012 15.3 6.3 2.4 3 0 0 3 3 3 0 Suppressor of forked protein (Suf) SET PF00856.23 EIE77548.1 - 0.089 13.0 0.4 0.2 11.9 0.3 1.5 1 0 0 1 1 1 0 SET domain DUF4557 PF15101.1 EIE77548.1 - 0.12 12.1 12.3 0.2 11.4 4.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) FAM176 PF14851.1 EIE77548.1 - 0.13 11.9 2.0 0.33 10.6 1.4 1.7 1 0 0 1 1 1 0 FAM176 family Plasmodium_Vir PF05795.6 EIE77548.1 - 0.19 10.8 1.0 0.29 10.2 0.7 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF4045 PF13254.1 EIE77548.1 - 0.25 10.5 8.9 0.38 9.9 6.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) RED_N PF07808.8 EIE77548.1 - 0.26 10.4 8.8 0.54 9.4 4.4 2.2 2 0 0 2 2 2 0 RED-like protein N-terminal region FPN1 PF06963.7 EIE77548.1 - 0.27 9.5 3.0 5.2 5.3 1.4 2.1 2 0 0 2 2 2 0 Ferroportin1 (FPN1) Phage_rep_org_N PF09681.5 EIE77548.1 - 0.43 10.1 4.6 0.54 9.8 2.0 2.0 2 0 0 2 2 2 0 N-terminal phage replisome organiser (Phage_rep_org_N) DUF2561 PF10812.3 EIE77548.1 - 0.47 10.0 2.1 4.9 6.6 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2561) PAT1 PF09770.4 EIE77548.1 - 0.63 8.2 35.6 1.1 7.3 24.7 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PH_4 PF15404.1 EIE77548.1 - 0.79 9.2 6.6 6.2 6.3 2.8 2.4 2 0 0 2 2 2 0 Pleckstrin homology domain Serinc PF03348.10 EIE77548.1 - 1.4 7.5 10.8 0.077 11.6 3.5 1.7 1 1 0 2 2 2 0 Serine incorporator (Serinc) Glt_symporter PF03616.9 EIE77548.1 - 1.6 7.1 5.1 4.6 5.6 0.0 2.1 2 0 0 2 2 2 0 Sodium/glutamate symporter DUF3899 PF13038.1 EIE77548.1 - 3.8 7.7 6.3 4.5 7.4 0.0 2.6 3 0 0 3 3 2 0 Domain of unknown function (DUF3899) SpoIIE PF07228.7 EIE77549.1 - 5.8e-06 26.1 0.0 7.9e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 EIE77549.1 - 0.037 13.4 0.3 0.052 12.9 0.1 1.3 1 1 0 1 1 1 0 Protein phosphatase 2C PP2C_2 PF13672.1 EIE77549.1 - 0.062 12.6 0.6 0.27 10.5 0.2 2.0 1 1 0 1 1 1 0 Protein phosphatase 2C MFS_1 PF07690.11 EIE77550.1 - 1.1e-41 142.7 28.4 1.1e-41 142.7 19.7 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2964 PF11177.3 EIE77550.1 - 8.2 6.4 9.8 12 5.9 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2964) MFS_1 PF07690.11 EIE77551.1 - 1.4e-29 102.9 26.4 2.1e-29 102.3 18.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF202 PF02656.10 EIE77552.1 - 4.9e-18 65.1 2.0 4.9e-18 65.1 1.4 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF202) MadM PF03818.8 EIE77552.1 - 0.51 9.9 7.1 0.082 12.4 0.6 2.6 1 1 2 3 3 3 0 Malonate/sodium symporter MadM subunit DUF3112 PF11309.3 EIE77552.1 - 1.5 8.6 5.5 4 7.1 3.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3112) SdpI PF13630.1 EIE77552.1 - 2.1 8.1 7.9 2 8.1 4.0 2.0 1 1 1 2 2 2 0 SdpI/YhfL protein family FGGY_N PF00370.16 EIE77553.1 - 2.3e-24 86.0 0.0 3.5e-16 59.2 0.0 2.2 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 EIE77553.1 - 1.3e-22 80.4 0.0 2.4e-22 79.5 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain XPG_I PF00867.13 EIE77554.1 - 1.7e-08 34.4 0.2 5.2e-08 32.8 0.0 1.9 2 0 0 2 2 2 1 XPG I-region Cactin_mid PF10312.4 EIE77555.1 - 1.9e-64 216.4 8.4 1.9e-64 216.4 5.8 2.1 2 0 0 2 2 2 1 Conserved mid region of cactin CactinC_cactus PF09732.4 EIE77555.1 - 1.2e-58 196.1 7.9 2.4e-58 195.1 5.5 1.6 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein eIF-5a PF01287.15 EIE77555.1 - 2.2 8.3 6.2 6 6.8 0.2 3.3 3 0 0 3 3 3 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold PhoH PF02562.11 EIE77556.1 - 0.0038 16.4 0.0 0.0048 16.1 0.0 1.2 1 0 0 1 1 1 1 PhoH-like protein DUF687 PF05095.7 EIE77556.1 - 0.011 14.1 0.0 0.013 13.9 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF687) SpoU_methylase PF00588.14 EIE77557.1 - 3.2e-25 88.6 0.0 7.1e-25 87.5 0.0 1.6 1 0 0 1 1 1 1 SpoU rRNA Methylase family Kinesin PF00225.18 EIE77558.1 - 1.2e-65 221.4 0.4 1.2e-65 221.4 0.3 1.9 2 0 0 2 2 2 1 Kinesin motor domain 7TM_transglut PF14402.1 EIE77558.1 - 0.061 12.2 0.1 0.13 11.1 0.1 1.5 1 0 0 1 1 1 0 7 transmembrane helices usually fused to an inactive transglutaminase PGAMP PF07644.6 EIE77558.1 - 0.18 11.6 0.6 0.32 10.7 0.4 1.4 1 0 0 1 1 1 0 Planctomycete PGAMP UFD1 PF03152.9 EIE77560.1 - 9.2e-40 135.6 0.0 1.5e-39 134.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.12 EIE77560.1 - 0.0059 16.2 0.0 0.015 14.9 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 DUF3931 PF13082.1 EIE77560.1 - 0.02 14.7 1.2 0.043 13.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3931) Response_reg PF00072.19 EIE77561.1 - 4.6e-23 81.3 0.1 6.4e-23 80.9 0.1 1.2 1 0 0 1 1 1 1 Response regulator receiver domain TUG-UBL1 PF11470.3 EIE77563.1 - 0.13 12.2 0.2 0.2 11.6 0.1 1.4 1 0 0 1 1 1 0 GLUT4 regulating protein TUG SET PF00856.23 EIE77564.1 - 2.9e-11 43.9 3.0 1.4e-09 38.5 0.0 3.0 2 2 1 3 3 3 2 SET domain IncA PF04156.9 EIE77564.1 - 0.36 10.4 2.7 0.66 9.5 1.8 1.4 1 0 0 1 1 1 0 IncA protein Y_phosphatase3 PF13350.1 EIE77569.1 - 4.3e-17 62.8 0.0 5.2e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.8 EIE77569.1 - 6.2e-05 22.4 0.0 8.8e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 EIE77569.1 - 0.099 11.9 0.0 0.13 11.5 0.0 1.4 1 1 0 1 1 1 0 Protein-tyrosine phosphatase HEAT PF02985.17 EIE77570.1 - 0.013 15.4 2.6 8.8 6.7 0.0 4.7 4 1 1 5 5 5 0 HEAT repeat NUC194 PF08163.7 EIE77571.1 - 3.5e-41 141.3 5.0 7.3e-41 140.3 3.5 1.6 1 0 0 1 1 1 1 NUC194 domain PI3_PI4_kinase PF00454.22 EIE77571.1 - 7.5e-40 136.8 0.0 9.9e-39 133.1 0.0 2.6 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 EIE77571.1 - 2.1e-10 39.8 0.1 5.4e-10 38.5 0.1 1.7 1 0 0 1 1 1 1 FATC domain Cmc1 PF08583.5 EIE77572.1 - 0.00011 21.8 9.3 0.018 14.7 1.3 2.8 2 1 0 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.8 EIE77572.1 - 0.00017 21.4 7.9 0.032 14.1 0.1 2.7 2 1 0 2 2 2 2 CHCH domain Pet191_N PF10203.4 EIE77572.1 - 0.011 15.7 9.9 0.078 13.0 5.3 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 DUF1903 PF08991.5 EIE77572.1 - 0.038 14.1 1.3 0.038 14.1 0.9 2.2 1 1 2 3 3 3 0 Domain of unknown function (DUF1903) DUF29 PF01724.11 EIE77572.1 - 0.059 13.2 0.0 0.06 13.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF29 PADR1 PF08063.7 EIE77572.1 - 0.08 12.3 0.8 0.18 11.2 0.2 1.9 1 1 1 2 2 2 0 PADR1 (NUC008) domain COX17 PF05051.8 EIE77572.1 - 0.6 10.1 7.0 0.068 13.2 1.3 2.1 2 1 0 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) UCR_hinge PF02320.11 EIE77572.1 - 2.4 8.1 8.7 2.1 8.3 0.6 2.9 1 1 0 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein Aminotran_1_2 PF00155.16 EIE77573.1 - 1e-37 129.9 0.0 1.5e-37 129.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EIE77573.1 - 8.6e-06 25.0 0.0 1.5e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase zf-C5HC2 PF02928.11 EIE77575.1 - 0.12 12.4 12.9 0.24 11.4 2.0 2.4 2 0 0 2 2 2 0 C5HC2 zinc finger DDE_1 PF03184.14 EIE77577.1 - 8.8e-06 25.0 0.4 0.089 11.9 0.0 2.4 1 1 1 2 2 2 2 DDE superfamily endonuclease Methyltransf_25 PF13649.1 EIE77577.1 - 0.011 16.0 0.1 0.13 12.6 0.0 2.4 1 1 1 3 3 3 0 Methyltransferase domain Gp37_Gp68 PF07505.6 EIE77577.1 - 0.029 13.5 0.0 0.045 12.9 0.0 1.3 1 0 0 1 1 1 0 Phage protein Gp37/Gp68 Flavodoxin_1 PF00258.20 EIE77577.1 - 0.047 13.6 0.1 0.081 12.9 0.0 1.5 1 0 0 1 1 1 0 Flavodoxin Myc_N PF01056.13 EIE77577.1 - 0.31 10.1 2.7 0.45 9.6 1.9 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Rho_GDI PF02115.12 EIE77581.1 - 1.5e-48 164.9 11.8 1.9e-35 122.0 0.2 3.4 3 1 1 4 4 4 2 RHO protein GDP dissociation inhibitor SH3_1 PF00018.23 EIE77581.1 - 7.3e-20 70.1 0.0 1.7e-09 36.9 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 EIE77581.1 - 1.2e-12 47.2 0.0 1.1e-07 31.3 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.19 EIE77581.1 - 4.5e-10 39.3 0.0 1.4e-09 37.7 0.0 1.8 1 0 0 1 1 1 1 PX domain SH3_2 PF07653.12 EIE77581.1 - 1.2e-08 34.2 0.0 4.9e-06 25.9 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain Bax1-I PF01027.15 EIE77582.1 - 9.5e-05 22.0 8.5 0.00012 21.7 5.9 1.1 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF3272 PF11676.3 EIE77582.1 - 0.085 12.8 3.5 0.12 12.4 0.7 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3272) DUF4282 PF14110.1 EIE77582.1 - 2.9 8.1 7.6 0.64 10.2 2.6 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4282) Pkinase PF00069.20 EIE77583.1 - 1.6e-46 158.6 0.0 2.7e-46 157.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE77583.1 - 2e-36 125.4 0.0 3.3e-36 124.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE77583.1 - 0.0008 18.4 0.0 0.14 11.1 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 EIE77583.1 - 0.024 13.6 0.0 0.047 12.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HAMP PF00672.20 EIE77585.1 - 7.7e-114 371.9 49.4 2.9e-08 33.7 0.1 16.1 15 1 1 16 16 16 14 HAMP domain HATPase_c PF02518.21 EIE77585.1 - 3.6e-31 107.1 0.2 1.6e-30 105.0 0.1 2.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EIE77585.1 - 4.4e-25 87.8 0.7 2.3e-24 85.5 0.2 2.5 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 EIE77585.1 - 6.2e-19 67.7 0.4 1e-17 63.8 0.4 3.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HTH_6 PF01418.12 EIE77585.1 - 4.7e-09 35.8 10.0 31 4.3 0.0 12.2 13 0 0 13 13 13 0 Helix-turn-helix domain, rpiR family RNA_pol_Rpb2_4 PF04566.8 EIE77585.1 - 3.2e-06 26.8 3.5 36 4.2 0.0 8.3 10 0 0 10 10 10 0 RNA polymerase Rpb2, domain 4 Pox_A_type_inc PF04508.7 EIE77585.1 - 7.7e-05 22.1 0.2 0.15 11.8 0.0 5.1 4 0 0 4 4 4 1 Viral A-type inclusion protein repeat HMG_box PF00505.14 EIE77585.1 - 8.7e-05 22.7 0.0 60 4.0 0.0 6.3 6 0 0 6 6 5 0 HMG (high mobility group) box SpoIIID PF12116.3 EIE77585.1 - 0.0004 20.2 25.7 1.1 9.2 0.2 12.2 15 0 0 15 15 15 1 Stage III sporulation protein D PilJ PF13675.1 EIE77585.1 - 0.33 11.2 6.4 4.8 7.5 0.0 6.0 7 1 1 8 8 8 0 Type IV pili methyl-accepting chemotaxis transducer N-term NAAA-beta PF15508.1 EIE77585.1 - 5.7 7.3 10.0 17 5.8 0.1 7.1 9 2 3 12 12 12 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase HsbA PF12296.3 EIE77586.1 - 1.4e-15 57.2 12.7 8.7e-13 48.2 2.9 2.2 1 1 1 2 2 2 2 Hydrophobic surface binding protein A NPV_P10 PF05531.7 EIE77586.1 - 0.0078 16.4 5.7 0.57 10.4 0.1 3.1 3 0 0 3 3 3 1 Nucleopolyhedrovirus P10 protein Serine_rich PF08824.5 EIE77586.1 - 0.1 12.2 1.6 2.2 7.9 0.1 2.1 1 1 1 2 2 2 0 Serine rich protein interaction domain TraW_N PF12477.3 EIE77586.1 - 0.15 12.0 1.8 0.48 10.4 1.3 2.0 1 0 0 1 1 1 0 Sex factor F TraW protein N terminal TrbC PF04956.8 EIE77586.1 - 0.56 10.2 6.7 0.077 13.0 1.5 2.0 2 1 1 3 3 3 0 TrbC/VIRB2 family DUF4376 PF14301.1 EIE77586.1 - 1.2 9.2 7.5 2.3 8.3 0.4 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4376) Homeobox PF00046.24 EIE77587.1 - 4.4e-17 61.4 5.5 7.7e-17 60.6 3.8 1.4 1 0 0 1 1 1 1 Homeobox domain MFS_2 PF13347.1 EIE77588.1 - 0.7 8.2 8.3 0.85 7.9 5.8 1.0 1 0 0 1 1 1 0 MFS/sugar transport protein DUF1682 PF07946.9 EIE77589.1 - 1e-68 231.6 1.3 1.2e-68 231.3 0.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) DUF4355 PF14265.1 EIE77589.1 - 0.0012 18.7 25.5 0.0023 17.8 17.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4355) DUF4306 PF14154.1 EIE77589.1 - 0.038 13.9 0.5 11 6.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4306) SWI-SNF_Ssr4 PF08549.5 EIE77589.1 - 7.4 4.7 9.9 11 4.2 6.9 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) ATP-grasp_2 PF08442.5 EIE77590.1 - 1.3e-79 266.2 0.1 2.1e-79 265.5 0.1 1.3 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 EIE77590.1 - 1.8e-24 86.1 0.7 2.9e-24 85.4 0.5 1.4 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 EIE77590.1 - 2e-09 36.9 0.0 4.7e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 EIE77590.1 - 8.8e-06 25.4 0.7 0.015 14.8 0.0 3.1 2 1 0 3 3 3 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_4 PF13535.1 EIE77590.1 - 0.013 15.2 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain PASTA PF03793.14 EIE77590.1 - 0.032 13.8 1.5 11 5.7 0.0 3.5 3 0 0 3 3 3 0 PASTA domain Succ_CoA_lig PF13607.1 EIE77590.1 - 0.059 12.9 0.2 1.8 8.1 0.0 2.5 1 1 1 2 2 2 0 Succinyl-CoA ligase like flavodoxin domain HipA_N PF07805.7 EIE77590.1 - 0.06 13.5 0.1 0.34 11.1 0.0 2.4 3 0 0 3 3 3 0 HipA-like N-terminal domain 6PF2K PF01591.13 EIE77592.1 - 2.1e-71 239.5 0.0 3.4e-71 238.8 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EIE77592.1 - 2e-27 96.2 0.2 2.2e-26 92.8 0.0 2.4 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EIE77592.1 - 3.4e-10 39.9 0.1 5.8e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 EIE77592.1 - 5.5e-05 22.5 0.0 9.3e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Zeta_toxin PF06414.7 EIE77592.1 - 6.9e-05 22.0 0.0 0.00012 21.2 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.1 EIE77592.1 - 0.00024 21.8 0.0 0.00073 20.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain Sugar_tr PF00083.19 EIE77593.1 - 2.8e-106 355.8 19.9 3.2e-106 355.6 13.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIE77593.1 - 4.7e-27 94.6 31.9 4.2e-21 75.0 4.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EIE77593.1 - 1.7e-05 23.2 0.6 1.7e-05 23.2 0.4 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF1228 PF06779.9 EIE77593.1 - 0.051 13.5 11.0 0.41 10.7 0.3 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) PRA1 PF03208.14 EIE77594.1 - 2.3e-30 104.9 2.5 2.9e-30 104.6 1.7 1.1 1 0 0 1 1 1 1 PRA1 family protein DUF2207 PF09972.4 EIE77594.1 - 0.56 8.7 2.4 0.64 8.5 1.7 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Tic20 PF09685.5 EIE77594.1 - 6.7 6.7 10.3 7.4 6.6 2.1 2.2 2 0 0 2 2 2 0 Tic20-like protein Y_phosphatase2 PF03162.8 EIE77595.1 - 4.9e-18 65.0 0.0 5.6e-18 64.8 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Methyltransf_23 PF13489.1 EIE77596.1 - 2.4e-13 50.1 0.1 3.4e-13 49.6 0.1 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIE77596.1 - 2e-09 37.8 0.0 3.5e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIE77596.1 - 2.8e-05 23.7 0.0 3.8e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIE77596.1 - 7.2e-05 23.1 0.0 0.00011 22.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIE77596.1 - 0.058 13.7 0.0 0.093 13.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain ORC4_C PF14629.1 EIE77596.1 - 0.11 11.8 1.9 0.2 11.0 0.2 1.9 1 1 1 2 2 2 0 Origin recognition complex (ORC) subunit 4 C-terminus DEAD PF00270.24 EIE77597.1 - 3.1e-44 150.4 1.9 4e-44 150.0 0.5 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIE77597.1 - 4.3e-27 93.7 0.7 1.7e-26 91.8 0.2 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIE77597.1 - 0.0067 16.2 0.1 0.02 14.7 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 EIE77597.1 - 0.0088 14.4 0.0 2.2 6.6 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1253) CMS1 PF14617.1 EIE77597.1 - 0.026 13.6 0.0 0.054 12.5 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit AAA_19 PF13245.1 EIE77597.1 - 0.032 13.9 0.3 0.11 12.2 0.0 2.0 2 0 0 2 2 2 0 Part of AAA domain AAA_30 PF13604.1 EIE77597.1 - 0.032 13.8 0.0 0.11 12.0 0.0 1.8 2 1 0 2 2 2 0 AAA domain tRNA-synt_1b PF00579.20 EIE77597.1 - 0.097 11.7 0.0 0.45 9.5 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) Cyclin_N PF00134.18 EIE77598.1 - 6.7e-14 51.5 0.4 1.3e-12 47.3 0.0 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.14 EIE77598.1 - 3e-07 30.1 0.1 1e-05 25.2 0.0 2.5 2 1 0 2 2 2 1 Transcription factor TFIIB repeat DPBB_1 PF03330.13 EIE77599.1 - 3.4e-09 36.5 0.0 8e-09 35.3 0.0 1.7 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Cons_hypoth698 PF03601.9 EIE77600.1 - 1.7e-36 125.4 12.3 8.9e-31 106.6 7.1 2.1 2 0 0 2 2 2 2 Conserved hypothetical protein 698 Glt_symporter PF03616.9 EIE77600.1 - 0.0034 15.9 8.3 0.0034 15.9 0.8 2.2 2 0 0 2 2 2 2 Sodium/glutamate symporter Ribosomal_S19 PF00203.16 EIE77601.1 - 2.6e-34 116.6 0.2 3.6e-34 116.2 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 FliH PF02108.11 EIE77601.1 - 0.1 12.4 0.0 0.13 12.1 0.0 1.1 1 0 0 1 1 1 0 Flagellar assembly protein FliH Peptidase_S28 PF05577.7 EIE77602.1 - 1.6e-51 175.2 0.0 1.9e-51 175.0 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_6 PF12697.2 EIE77602.1 - 0.00029 20.7 0.0 0.00061 19.7 0.0 1.4 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EIE77602.1 - 0.071 12.3 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Antigen_Bd37 PF11641.3 EIE77603.1 - 0.054 12.7 1.1 0.18 11.0 0.8 1.7 1 1 1 2 2 2 0 Glycosylphosphatidylinositol-anchored merozoite surface protein V_ATPase_I PF01496.14 EIE77603.1 - 0.22 9.3 8.9 0.32 8.8 6.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 EIE77603.1 - 0.54 9.8 18.1 0.88 9.1 12.5 1.3 1 0 0 1 1 1 0 IncA protein TFIIA PF03153.8 EIE77603.1 - 1.7 8.4 26.5 2.5 7.8 18.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TSA PF03249.8 EIE77603.1 - 2.5 6.5 13.3 3.8 5.9 9.2 1.2 1 0 0 1 1 1 0 Type specific antigen MMR_HSR1 PF01926.18 EIE77604.1 - 1.2e-05 25.2 0.1 0.00026 20.8 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EIE77604.1 - 0.00013 21.4 0.0 0.0014 18.1 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EIE77604.1 - 0.0031 16.8 0.1 0.94 8.7 0.0 2.6 3 0 0 3 3 3 2 Ferrous iron transport protein B Miro PF08477.8 EIE77604.1 - 0.042 14.3 0.1 0.27 11.7 0.0 2.4 3 1 0 3 3 3 0 Miro-like protein PSCyt2 PF07583.6 EIE77604.1 - 0.061 12.8 0.1 0.97 8.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1549) RNA_helicase PF00910.17 EIE77604.1 - 0.068 13.3 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.1 EIE77604.1 - 0.092 12.8 0.2 1.5 8.9 0.0 2.6 1 1 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.4 EIE77604.1 - 0.11 11.1 0.1 0.6 8.6 0.0 2.1 2 1 1 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain Ras PF00071.17 EIE77604.1 - 0.11 11.8 0.1 0.94 8.8 0.1 2.4 2 1 1 3 3 3 0 Ras family MIR PF02815.14 EIE77605.1 - 3.6e-13 49.4 0.1 7.8e-13 48.3 0.1 1.6 1 1 0 1 1 1 1 MIR domain Ins145_P3_rec PF08709.6 EIE77605.1 - 0.032 13.2 0.0 0.054 12.5 0.0 1.3 1 0 0 1 1 1 0 Inositol 1,4,5-trisphosphate/ryanodine receptor PMT PF02366.13 EIE77606.1 - 3.6e-57 193.5 10.8 4.6e-57 193.2 7.5 1.1 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase DUF4239 PF14023.1 EIE77606.1 - 1 8.6 6.0 0.73 9.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4239) Ribosomal_L31e PF01198.14 EIE77609.1 - 1.9e-31 107.5 3.9 2.3e-31 107.2 2.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e Dynamitin PF04912.9 EIE77610.1 - 2.8e-25 88.9 7.7 1.5e-13 50.3 0.1 2.0 2 0 0 2 2 2 2 Dynamitin RPW8 PF05659.6 EIE77610.1 - 0.032 13.7 0.2 0.49 9.9 0.0 2.6 1 1 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF16 PF01519.11 EIE77610.1 - 0.05 13.8 2.8 4.4 7.5 0.2 2.4 1 1 0 2 2 2 0 Protein of unknown function DUF16 bZIP_1 PF00170.16 EIE77610.1 - 0.094 12.6 2.0 0.64 10.0 0.0 2.9 2 2 1 3 3 3 0 bZIP transcription factor Seryl_tRNA_N PF02403.17 EIE77610.1 - 0.11 12.5 4.1 0.93 9.5 0.1 3.0 1 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF342 PF03961.8 EIE77610.1 - 0.16 10.3 0.8 0.37 9.1 0.5 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Ran-binding PF05508.6 EIE77610.1 - 0.25 10.2 3.4 0.69 8.7 2.0 2.0 1 1 1 2 2 2 0 RanGTP-binding protein Spectrin PF00435.16 EIE77610.1 - 0.27 11.5 4.8 5.3 7.3 0.2 2.8 2 1 0 2 2 2 0 Spectrin repeat DUF948 PF06103.6 EIE77610.1 - 0.51 10.2 4.0 4.8 7.1 0.4 3.4 2 2 2 4 4 4 0 Bacterial protein of unknown function (DUF948) Prefoldin_2 PF01920.15 EIE77610.1 - 1.8 8.4 7.0 3.5 7.4 0.1 3.3 4 0 0 4 4 4 0 Prefoldin subunit Dynamitin PF04912.9 EIE77611.1 - 6.4e-23 81.1 5.4 7.3e-23 80.9 3.7 1.0 1 0 0 1 1 1 1 Dynamitin DUF4150 PF13665.1 EIE77611.1 - 0.068 13.0 0.1 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4150) TFIIS_C PF01096.13 EIE77612.1 - 7e-17 60.7 1.8 7e-17 60.7 1.2 2.0 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) DUF523 PF04463.7 EIE77612.1 - 0.00012 21.8 0.6 0.00014 21.6 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF523) Lar_restr_allev PF14354.1 EIE77612.1 - 0.0013 18.9 1.7 0.0013 18.9 1.2 2.2 1 1 1 2 2 2 1 Restriction alleviation protein Lar Terminase_GpA PF05876.7 EIE77612.1 - 0.0056 15.0 2.2 0.0057 15.0 1.5 1.1 1 0 0 1 1 1 1 Phage terminase large subunit (GpA) Zn_Tnp_IS1595 PF12760.2 EIE77612.1 - 0.0083 15.9 4.0 0.028 14.2 1.0 2.4 2 0 0 2 2 2 1 Transposase zinc-ribbon domain GATA PF00320.22 EIE77612.1 - 0.013 14.8 3.7 1.1 8.6 0.1 2.5 2 0 0 2 2 2 0 GATA zinc finger Rpr2 PF04032.11 EIE77612.1 - 0.015 15.1 1.2 0.015 15.1 0.8 1.7 1 1 1 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zinc_ribbon_2 PF13240.1 EIE77612.1 - 0.051 13.0 9.2 0.95 9.0 0.7 2.9 3 0 0 3 3 3 0 zinc-ribbon domain Baculo_LEF5_C PF11792.3 EIE77612.1 - 0.058 12.7 1.1 0.058 12.7 0.8 2.6 3 1 0 3 3 3 0 Baculoviridae late expression factor 5 C-terminal domain PolC_DP2 PF03833.8 EIE77612.1 - 0.12 9.9 0.8 0.13 9.8 0.5 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-CSL PF05207.8 EIE77612.1 - 0.13 11.8 9.2 0.22 11.0 0.1 3.1 2 1 0 3 3 3 0 CSL zinc finger tRNA-synt_1f PF01921.13 EIE77612.1 - 0.13 10.8 0.4 0.14 10.7 0.3 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (K) Viral_NABP PF05515.6 EIE77612.1 - 0.17 12.1 1.4 0.12 12.6 0.2 1.4 1 1 0 1 1 1 0 Viral nucleic acid binding zf-ribbon_3 PF13248.1 EIE77612.1 - 0.31 10.2 0.3 0.31 10.2 0.2 2.7 3 0 0 3 3 3 0 zinc-ribbon domain Elf1 PF05129.8 EIE77612.1 - 0.35 10.6 6.3 0.081 12.6 1.1 2.0 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like DUF2387 PF09526.5 EIE77612.1 - 0.36 10.7 0.1 0.36 10.7 0.1 2.2 1 1 1 2 2 2 0 Probable metal-binding protein (DUF2387) Prok-RING_1 PF14446.1 EIE77612.1 - 0.4 10.4 6.2 4.9 6.9 0.2 3.1 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 A2L_zn_ribbon PF08792.5 EIE77612.1 - 0.46 10.0 10.5 3.7 7.1 0.6 3.2 3 0 0 3 3 3 0 A2L zinc ribbon domain zf-HYPF PF07503.7 EIE77612.1 - 0.51 9.7 0.1 0.51 9.7 0.0 2.8 3 0 0 3 3 3 0 HypF finger Zn-ribbon_8 PF09723.5 EIE77612.1 - 0.73 9.8 11.0 2.2 8.2 0.1 3.3 3 0 0 3 3 3 0 Zinc ribbon domain Auto_anti-p27 PF06677.7 EIE77612.1 - 0.83 9.4 0.1 0.83 9.4 0.1 2.5 3 0 0 3 3 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-TFIIB PF13453.1 EIE77612.1 - 0.92 8.7 6.2 0.1 11.8 1.1 1.8 2 0 0 2 2 2 0 Transcription factor zinc-finger PHD PF00628.24 EIE77612.1 - 1.1 8.9 6.2 7.3 6.3 0.1 2.4 2 1 0 2 2 2 0 PHD-finger Ribosomal_L37e PF01907.14 EIE77612.1 - 1.4 8.7 0.1 1.4 8.7 0.0 2.8 4 0 0 4 4 2 0 Ribosomal protein L37e eIF-5_eIF-2B PF01873.12 EIE77612.1 - 1.9 8.1 7.2 0.044 13.4 0.6 1.6 2 1 0 2 2 1 0 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.7 EIE77612.1 - 2.2 7.6 8.1 0.34 10.2 2.0 2.2 2 1 0 2 2 1 0 TFIIB zinc-binding DUF2321 PF10083.4 EIE77612.1 - 2.4 7.6 5.4 1.2 8.6 1.7 1.8 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) zf-IS66 PF13005.2 EIE77612.1 - 2.9 7.9 7.6 7.5 6.6 0.1 3.1 3 0 0 3 3 3 0 zinc-finger binding domain of transposase IS66 Zn_ribbon_recom PF13408.1 EIE77612.1 - 3.6 7.9 6.3 8.1 6.7 2.7 2.5 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain zinc_ribbon_5 PF13719.1 EIE77612.1 - 4.8 6.8 11.8 3.8 7.1 0.4 3.1 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EIE77612.1 - 6 6.6 12.4 3.8 7.2 0.5 3.1 3 0 0 3 3 3 0 zinc-ribbon domain RIG-I_C-RD PF11648.3 EIE77612.1 - 6.3 6.6 7.0 0.55 10.1 1.2 1.8 1 1 1 2 2 2 0 C-terminal domain of RIG-I DZR PF12773.2 EIE77612.1 - 7.9 6.3 11.1 2.7e+02 1.4 7.7 2.7 1 1 0 1 1 1 0 Double zinc ribbon Nudix_N_2 PF14803.1 EIE77612.1 - 9 6.0 8.2 5 6.8 0.1 3.1 3 0 0 3 3 3 0 Nudix N-terminal zf-ZPR1 PF03367.8 EIE77612.1 - 9.9 5.2 8.0 5.1 6.2 1.7 2.4 1 1 1 2 2 2 0 ZPR1 zinc-finger domain W2 PF02020.13 EIE77613.1 - 8.6e-20 70.4 3.4 8.6e-20 70.4 2.3 2.5 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.19 EIE77613.1 - 1e-11 43.7 15.1 6.5e-05 22.2 0.6 4.4 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EIE77613.1 - 3.3e-07 29.7 12.8 2.8e-06 26.7 0.5 3.3 1 1 2 3 3 3 2 Hexapeptide repeat of succinyl-transferase NTP_transferase PF00483.18 EIE77613.1 - 5.7e-06 25.7 0.0 1e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 EIE77613.1 - 0.06 13.4 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 MobA-like NTP transferase domain DUF2004 PF09406.5 EIE77614.1 - 0.097 12.7 1.1 4.6 7.3 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2004) DUF1746 PF08508.5 EIE77616.1 - 2.6e-05 24.1 5.3 0.00034 20.5 3.6 2.6 1 1 0 1 1 1 1 Fungal domain of unknown function (DUF1746) PPR_2 PF13041.1 EIE77617.1 - 5.1e-72 237.6 31.8 6.5e-13 48.4 0.0 19.1 12 4 9 21 21 20 15 PPR repeat family PPR PF01535.15 EIE77617.1 - 1.3e-45 150.1 44.7 3.3e-06 26.7 0.1 19.8 23 0 0 23 23 23 9 PPR repeat PPR_3 PF13812.1 EIE77617.1 - 5.2e-45 147.9 13.7 9e-06 25.5 0.0 17.8 19 0 0 19 19 19 8 Pentatricopeptide repeat domain PPR_1 PF12854.2 EIE77617.1 - 2.7e-37 125.9 8.3 9.6e-06 24.9 0.0 14.0 15 0 0 15 15 15 9 PPR repeat TPR_19 PF14559.1 EIE77617.1 - 7.6e-09 35.7 17.0 0.17 12.2 0.2 8.6 9 2 0 9 9 8 3 Tetratricopeptide repeat TPR_14 PF13428.1 EIE77617.1 - 1.3e-07 31.6 3.5 53 4.8 0.0 10.6 13 2 2 15 15 9 0 Tetratricopeptide repeat RPM2 PF08579.6 EIE77617.1 - 1.5e-06 28.3 0.2 0.0075 16.3 0.0 4.9 5 0 0 5 5 5 1 Mitochondrial ribonuclease P subunit (RPM2) TPR_12 PF13424.1 EIE77617.1 - 9.2e-06 25.5 15.0 0.043 13.7 0.0 7.5 9 0 0 9 9 8 2 Tetratricopeptide repeat ECSIT PF06239.6 EIE77617.1 - 2.3e-05 23.3 0.9 0.62 8.8 0.0 5.3 5 1 0 5 5 5 1 Evolutionarily conserved signalling intermediate in Toll pathway TPR_16 PF13432.1 EIE77617.1 - 0.0002 21.9 7.0 8.8 7.1 0.0 7.4 8 0 0 8 8 8 1 Tetratricopeptide repeat ATP13 PF12921.2 EIE77617.1 - 0.0056 16.0 1.8 16 4.9 0.0 5.3 6 0 0 6 6 6 0 Mitochondrial ATPase expression TPR_8 PF13181.1 EIE77617.1 - 0.038 13.7 14.8 2.7 7.9 0.3 6.6 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_6 PF13174.1 EIE77617.1 - 0.039 14.4 12.2 1.3e+02 3.3 0.1 8.8 10 0 0 10 10 8 0 Tetratricopeptide repeat TPR_1 PF00515.23 EIE77617.1 - 0.11 12.1 4.2 47 3.8 0.0 5.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Lipase_3 PF01764.20 EIE77618.1 - 4.3e-18 65.2 0.0 3.9e-17 62.1 0.0 2.4 1 1 0 1 1 1 1 Lipase (class 3) Ricin_B_lectin PF00652.17 EIE77619.1 - 0.0003 20.7 0.0 0.00056 19.9 0.0 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Tub_2 PF04525.7 EIE77619.1 - 0.12 11.6 0.0 0.32 10.3 0.0 1.6 1 1 0 1 1 1 0 Tubby C 2 LIM PF00412.17 EIE77620.1 - 2.7e-52 174.6 43.2 3e-15 56.0 1.7 4.3 4 0 0 4 4 4 4 LIM domain Zn_ribbon_recom PF13408.1 EIE77620.1 - 4.9 7.4 25.2 6.1 7.1 0.7 5.1 4 1 0 4 4 4 0 Recombinase zinc beta ribbon domain AMP-binding PF00501.23 EIE77621.1 - 2.7e-94 315.9 0.0 3.6e-94 315.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Methyltransf_31 PF13847.1 EIE77623.1 - 7.3e-14 51.6 0.0 1.8e-13 50.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.6 EIE77623.1 - 3e-10 39.3 0.1 6.9e-10 38.1 0.0 1.5 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_26 PF13659.1 EIE77623.1 - 7.6e-09 35.6 0.0 1.6e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EIE77623.1 - 1e-08 34.7 0.1 1.8e-08 33.9 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.5 EIE77623.1 - 1.7e-07 30.9 0.0 3.1e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_18 PF12847.2 EIE77623.1 - 5.4e-07 30.1 0.0 2.2e-06 28.2 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIE77623.1 - 0.00016 21.9 0.0 0.00037 20.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 EIE77623.1 - 0.00018 20.9 0.0 0.00041 19.8 0.0 1.6 1 0 0 1 1 1 1 Conserved hypothetical protein 95 PrmA PF06325.8 EIE77623.1 - 0.00065 18.9 0.3 0.00065 18.9 0.2 1.9 2 0 0 2 2 1 1 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.13 EIE77623.1 - 0.0012 18.4 0.0 0.0027 17.2 0.0 1.6 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_4 PF02390.12 EIE77623.1 - 0.0012 17.8 0.1 0.0012 17.8 0.1 2.1 2 0 0 2 2 2 1 Putative methyltransferase Ubie_methyltran PF01209.13 EIE77623.1 - 0.0029 16.7 0.1 0.0053 15.9 0.1 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Met_10 PF02475.11 EIE77623.1 - 0.0035 16.9 0.0 0.0083 15.7 0.0 1.6 1 0 0 1 1 1 1 Met-10+ like-protein PCMT PF01135.14 EIE77623.1 - 0.0056 16.2 0.0 0.012 15.1 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) AviRa PF11599.3 EIE77623.1 - 0.0088 15.0 0.0 0.018 14.0 0.0 1.5 1 0 0 1 1 1 1 RRNA methyltransferase AviRa Methyltransf_11 PF08241.7 EIE77623.1 - 0.013 15.9 0.1 0.05 14.1 0.0 2.1 2 0 0 2 2 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 EIE77623.1 - 0.032 13.9 0.1 0.032 13.9 0.1 2.0 3 0 0 3 3 2 0 Methyltransferase domain Methyltransf_23 PF13489.1 EIE77623.1 - 0.065 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain ATP_bind_1 PF03029.12 EIE77624.1 - 1.5e-70 237.4 0.2 9.1e-62 208.6 0.0 2.0 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein CbiA PF01656.18 EIE77624.1 - 2e-05 24.1 0.6 0.00011 21.6 0.4 2.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_17 PF13207.1 EIE77624.1 - 0.00022 22.0 3.4 0.0011 19.8 2.3 2.1 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EIE77624.1 - 0.001 18.7 0.1 0.0027 17.3 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EIE77624.1 - 0.0012 18.3 0.0 0.0025 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA-like domain ArgK PF03308.11 EIE77624.1 - 0.0014 17.5 0.3 0.005 15.6 0.0 1.8 2 0 0 2 2 2 1 ArgK protein FtsK_SpoIIIE PF01580.13 EIE77624.1 - 0.0018 17.7 1.7 0.0029 17.1 0.0 2.0 2 1 0 2 2 2 1 FtsK/SpoIIIE family MobB PF03205.9 EIE77624.1 - 0.0069 16.0 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 EIE77624.1 - 0.007 16.6 4.0 0.41 10.9 0.0 2.6 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 EIE77624.1 - 0.008 16.1 0.0 0.025 14.5 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain SRP54 PF00448.17 EIE77624.1 - 0.011 15.2 0.0 0.019 14.4 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain FimP PF09766.4 EIE77624.1 - 0.013 14.6 0.4 0.017 14.1 0.3 1.1 1 0 0 1 1 1 0 Fms-interacting protein NTPase_1 PF03266.10 EIE77624.1 - 0.014 15.0 0.0 5.3 6.7 0.0 2.3 2 0 0 2 2 2 0 NTPase AAA_29 PF13555.1 EIE77624.1 - 0.021 14.3 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.1 EIE77624.1 - 0.026 14.0 0.0 0.048 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 EIE77624.1 - 0.027 13.3 0.0 0.093 11.6 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_22 PF13401.1 EIE77624.1 - 0.036 14.1 1.5 0.18 11.9 0.0 2.2 1 1 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EIE77624.1 - 0.038 14.2 0.0 0.099 12.9 0.0 1.7 2 0 0 2 2 2 0 ABC transporter AAA_33 PF13671.1 EIE77624.1 - 0.049 13.5 0.4 0.11 12.4 0.0 1.7 2 0 0 2 2 1 0 AAA domain SPT6_acidic PF14632.1 EIE77624.1 - 0.052 13.7 11.4 0.11 12.6 7.9 1.6 1 0 0 1 1 1 0 Acidic N-terminal SPT6 AAA_19 PF13245.1 EIE77624.1 - 0.052 13.3 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Polyoma_lg_T_C PF06431.6 EIE77624.1 - 0.064 11.8 0.4 0.53 8.8 0.0 2.0 2 0 0 2 2 2 0 Polyomavirus large T antigen C-terminus ACT_4 PF13291.1 EIE77624.1 - 0.078 13.3 0.0 0.65 10.3 0.0 2.1 2 0 0 2 2 2 0 ACT domain ArsA_ATPase PF02374.10 EIE77624.1 - 0.079 11.9 0.4 0.16 10.9 0.0 1.7 2 0 0 2 2 2 0 Anion-transporting ATPase MipZ PF09140.6 EIE77624.1 - 0.085 11.9 0.7 4.2 6.3 0.0 2.7 3 0 0 3 3 3 0 ATPase MipZ Nucleoplasmin PF03066.10 EIE77624.1 - 0.17 11.4 2.6 0.31 10.5 1.8 1.4 1 0 0 1 1 1 0 Nucleoplasmin DUF506 PF04720.7 EIE77624.1 - 0.18 11.4 1.6 0.25 10.9 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF506) PBP1_TM PF14812.1 EIE77624.1 - 0.28 11.4 9.2 0.63 10.3 6.4 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CDC45 PF02724.9 EIE77624.1 - 1.7 6.5 6.0 2.3 6.1 4.2 1.1 1 0 0 1 1 1 0 CDC45-like protein WWE PF02825.15 EIE77625.1 - 0.00096 18.5 0.3 0.71 9.3 0.0 2.6 1 1 1 2 2 2 2 WWE domain DDHD PF02862.12 EIE77626.1 - 6.4e-53 179.8 0.0 8.6e-53 179.4 0.0 1.2 1 0 0 1 1 1 1 DDHD domain Complex1_LYR PF05347.10 EIE77627.1 - 9.3e-11 41.3 0.3 1.4e-10 40.8 0.2 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.1 EIE77627.1 - 2.2e-08 34.5 1.0 2.6e-08 34.2 0.7 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.1 EIE77627.1 - 2.5e-08 34.0 1.0 3.5e-08 33.5 0.7 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Lipoprotein_Ltp PF07553.6 EIE77627.1 - 0.1 12.4 0.2 0.32 10.8 0.0 1.9 2 0 0 2 2 2 0 Host cell surface-exposed lipoprotein Pkinase PF00069.20 EIE77628.1 - 2.9e-59 200.3 0.0 3.4e-59 200.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE77628.1 - 2.1e-31 108.9 0.0 3e-31 108.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE77628.1 - 3.2e-10 39.4 0.0 4.8e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EIE77628.1 - 0.00075 19.3 0.0 0.0037 17.0 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EIE77628.1 - 0.0074 15.1 0.0 0.013 14.3 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 DEAD PF00270.24 EIE77629.1 - 7.3e-47 158.9 0.0 3.7e-46 156.7 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIE77629.1 - 3.3e-23 81.3 0.0 7.1e-23 80.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain NDUF_B8 PF05821.6 EIE77630.1 - 2.4e-10 40.3 0.1 4e-10 39.6 0.1 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) OKR_DC_1 PF01276.15 EIE77631.1 - 0.11 11.0 0.0 0.16 10.4 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Fasciclin PF02469.17 EIE77632.1 - 2.8e-81 269.8 0.0 9.9e-23 80.5 0.0 5.3 5 0 0 5 5 5 5 Fasciclin domain MFS_1 PF07690.11 EIE77633.1 - 1e-40 139.5 24.4 1.8e-40 138.7 16.9 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIE77633.1 - 6.4e-17 61.2 1.0 6.4e-17 61.2 0.7 2.9 2 1 1 3 3 3 1 Sugar (and other) transporter DUF997 PF06196.7 EIE77633.1 - 0.014 14.8 2.3 0.35 10.4 0.4 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF997) Pam17 PF08566.5 EIE77633.1 - 0.045 13.4 0.1 0.12 12.0 0.1 1.7 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 Ras PF00071.17 EIE77634.1 - 2.1e-55 186.4 0.0 2.4e-55 186.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIE77634.1 - 8e-18 65.0 0.0 1.1e-17 64.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIE77634.1 - 1.3e-08 34.2 0.0 1.6e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EIE77634.1 - 0.0014 18.1 0.0 0.012 15.0 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain HEAT_2 PF13646.1 EIE77636.1 - 0.043 14.0 0.1 0.063 13.5 0.1 1.2 1 0 0 1 1 1 0 HEAT repeats Atx10homo_assoc PF09759.4 EIE77637.1 - 4.7e-05 23.0 0.2 0.00044 19.9 0.1 2.1 1 1 1 2 2 2 1 Spinocerebellar ataxia type 10 protein domain V-ATPase_H_C PF11698.3 EIE77637.1 - 0.051 13.5 0.2 0.09 12.6 0.1 1.4 1 0 0 1 1 1 0 V-ATPase subunit H DUF1803 PF08820.5 EIE77637.1 - 0.12 12.1 0.2 0.26 10.9 0.1 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF1803) SPRY PF00622.23 EIE77638.1 - 6.9e-23 81.0 1.9 2.6e-22 79.1 0.1 2.5 2 0 0 2 2 2 1 SPRY domain SR-25 PF10500.4 EIE77638.1 - 0.0038 16.7 23.1 0.013 14.9 7.3 2.2 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein MUG2_C PF08593.5 EIE77638.1 - 0.04 14.1 2.6 0.098 12.9 0.4 2.7 2 0 0 2 2 2 0 Meiotically up-regulated glycoproteins C-terminal DUF755 PF05501.6 EIE77638.1 - 2.3 8.2 31.9 4 7.5 11.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Ank_4 PF13637.1 EIE77639.1 - 1.4e-14 54.1 3.7 6.8e-08 32.8 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 EIE77639.1 - 6.9e-11 41.3 2.2 4.1e-10 38.9 0.1 2.8 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.2 EIE77639.1 - 7.9e-11 42.1 0.9 2.1e-10 40.7 0.7 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EIE77639.1 - 6.5e-09 35.1 1.0 2.4e-06 27.2 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.1 EIE77639.1 - 3.2e-07 30.3 0.2 6.6e-07 29.3 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) TPR_8 PF13181.1 EIE77639.1 - 0.047 13.4 0.1 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat DDE_Tnp_1 PF01609.16 EIE77639.1 - 0.11 12.0 0.2 0.16 11.4 0.2 1.4 1 1 0 1 1 1 0 Transposase DDE domain LRR_4 PF12799.2 EIE77640.1 - 9.4e-20 69.8 30.2 1.7e-08 33.9 5.0 4.8 1 1 4 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EIE77640.1 - 2e-18 65.9 40.2 1.8e-08 34.0 5.4 3.4 1 1 3 4 4 4 4 Leucine rich repeat LRR_1 PF00560.28 EIE77640.1 - 1.5e-11 42.6 12.7 0.12 12.5 0.2 6.3 5 0 0 5 5 5 5 Leucine Rich Repeat LRR_7 PF13504.1 EIE77640.1 - 1.2e-09 36.7 15.4 0.11 12.7 0.2 6.2 5 0 0 5 5 5 5 Leucine rich repeat LRR_6 PF13516.1 EIE77640.1 - 0.00076 19.3 18.5 0.14 12.3 0.5 5.6 4 1 1 5 5 5 2 Leucine Rich repeat LRR_9 PF14580.1 EIE77640.1 - 0.017 14.6 5.6 0.57 9.7 0.3 2.3 1 1 1 2 2 2 0 Leucine-rich repeat JCAD PF15351.1 EIE77641.1 - 0.029 11.9 1.4 0.034 11.7 1.0 1.0 1 0 0 1 1 1 0 Junctional protein associated with coronary artery disease DUF1789 PF08748.6 EIE77641.1 - 4.2 7.4 7.9 2.6 8.1 3.4 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF1789) HTH_Tnp_Tc3_2 PF01498.13 EIE77644.1 - 2.2e-05 24.4 0.3 2.6e-05 24.2 0.2 1.2 1 0 0 1 1 1 1 Transposase Peptidase_C48 PF02902.14 EIE77647.1 - 6.9e-23 81.3 1.8 2.7e-22 79.4 0.0 2.2 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain HTH_Tnp_Tc3_2 PF01498.13 EIE77650.1 - 1.6e-16 60.0 1.1 3.5e-16 58.9 0.8 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.1 EIE77650.1 - 2.9e-16 59.5 0.0 5e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 EIE77650.1 - 2.3e-08 34.1 0.4 3.6e-07 30.3 0.0 2.7 3 0 0 3 3 3 1 Winged helix-turn helix HTH_23 PF13384.1 EIE77650.1 - 0.00016 21.2 0.1 0.00061 19.3 0.0 2.0 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.1 EIE77650.1 - 0.0018 18.2 0.0 0.0062 16.5 0.0 2.0 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_17 PF12728.2 EIE77650.1 - 0.0074 16.5 0.6 0.29 11.3 0.0 3.0 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_24 PF13412.1 EIE77650.1 - 0.011 15.1 0.0 0.14 11.5 0.0 2.5 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding HTH_38 PF13936.1 EIE77650.1 - 0.012 15.1 0.0 0.036 13.6 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_7 PF02796.10 EIE77650.1 - 0.046 13.5 0.4 1 9.2 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase SpoIIID PF12116.3 EIE77650.1 - 0.046 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Stage III sporulation protein D HTH_IclR PF09339.5 EIE77650.1 - 0.049 13.2 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain MerR PF00376.18 EIE77650.1 - 0.07 12.6 0.3 7.2 6.2 0.0 3.0 3 0 0 3 3 3 0 MerR family regulatory protein ADH_zinc_N PF00107.21 EIE77651.1 - 4.6e-12 45.6 0.0 7.4e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIE77651.1 - 2.3e-10 40.2 0.0 6e-10 38.8 0.0 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EIE77651.1 - 5e-06 27.4 0.0 8.8e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2855 PF11017.3 EIE77651.1 - 5.4e-05 22.5 0.0 0.00012 21.3 0.0 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF2855) Semialdhyde_dh PF01118.19 EIE77651.1 - 0.0014 18.9 0.0 0.0026 18.0 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Peptidase_C42 PF05533.7 EIE77651.1 - 0.064 13.0 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 Beet yellows virus-type papain-like endopeptidase C42 Ribosomal_S19e PF01090.14 EIE77652.1 - 3.1e-61 204.8 0.2 3.5e-61 204.7 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e GEMIN8 PF15348.1 EIE77653.1 - 0.025 14.6 8.4 0.03 14.3 5.8 1.1 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 DUF2106 PF09879.4 EIE77653.1 - 0.33 10.2 1.8 0.48 9.7 1.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2106) Paf67 PF10255.4 EIE77654.1 - 5e-155 516.3 8.1 6.8e-155 515.8 5.6 1.2 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.12 EIE77654.1 - 5.3e-05 22.8 0.3 0.00086 19.0 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EIE77654.1 - 0.00093 18.7 1.1 0.0046 16.5 0.0 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF2042 PF09743.4 EIE77654.1 - 0.0032 16.8 0.1 0.041 13.1 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2042) PCI_Csn8 PF10075.4 EIE77654.1 - 0.014 15.1 0.1 0.052 13.3 0.0 2.0 2 0 0 2 2 2 0 COP9 signalosome, subunit CSN8 TPR_11 PF13414.1 EIE77654.1 - 0.019 14.6 1.5 0.12 12.0 0.1 2.7 3 0 0 3 3 3 0 TPR repeat TPR_12 PF13424.1 EIE77654.1 - 0.021 14.7 0.2 0.2 11.6 0.1 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EIE77654.1 - 0.17 12.3 1.7 29 5.3 0.2 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2076 PF09849.4 EIE77655.1 - 3.4e-06 27.3 12.8 4.4e-06 26.9 8.9 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 EIE77655.1 - 0.0002 21.2 5.3 0.00029 20.6 3.7 1.3 1 0 0 1 1 1 1 CHCH domain DUF1903 PF08991.5 EIE77655.1 - 0.0068 16.5 2.0 0.012 15.7 1.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) RAB3GAP2_N PF14655.1 EIE77655.1 - 0.03 13.3 0.1 0.04 12.9 0.1 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus BCDHK_Adom3 PF10436.4 EIE77656.1 - 3.2e-22 78.7 0.0 2.2e-11 43.5 0.0 2.3 2 0 0 2 2 2 2 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EIE77656.1 - 1.9e-19 69.4 0.0 5.1e-19 68.0 0.0 1.8 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EIE77656.1 - 0.00056 19.5 0.0 0.001 18.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.1 EIE77656.1 - 0.011 15.4 0.0 0.041 13.5 0.0 2.0 1 1 0 1 1 1 0 GHKL domain Mpp10 PF04006.7 EIE77656.1 - 0.013 13.9 0.1 0.02 13.2 0.1 1.2 1 0 0 1 1 1 0 Mpp10 protein RasGEF PF00617.14 EIE77657.1 - 1.5e-37 129.1 0.0 3.4e-19 69.3 0.0 2.8 1 1 1 2 2 2 2 RasGEF domain RasGEF_N PF00618.15 EIE77657.1 - 1.2e-23 83.2 0.1 5.8e-23 80.9 0.1 2.3 2 0 0 2 2 2 1 RasGEF N-terminal motif WW PF00397.21 EIE77657.1 - 2.1e-08 33.8 5.3 6.8e-07 29.0 0.1 2.6 2 0 0 2 2 2 2 WW domain DUF2422 PF10337.4 EIE77657.1 - 0.011 14.5 1.1 0.093 11.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2422) Proteasome PF00227.21 EIE77659.1 - 2.4e-60 203.0 0.2 3.1e-60 202.7 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EIE77659.1 - 2e-14 52.5 0.0 3.6e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF3137 PF11335.3 EIE77659.1 - 0.043 13.4 0.2 6.5 6.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3137) RVT_1 PF00078.22 EIE77660.1 - 5.9e-27 94.4 0.0 1.4e-26 93.2 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EIE77660.1 - 7.1e-18 64.3 2.2 2.7e-17 62.4 1.5 2.1 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EIE77660.1 - 1.2e-07 31.9 0.1 2.8e-07 30.7 0.1 1.7 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Lar_restr_allev PF14354.1 EIE77660.1 - 0.018 15.3 1.5 0.039 14.2 0.4 2.1 2 0 0 2 2 2 0 Restriction alleviation protein Lar Zn_Tnp_IS1595 PF12760.2 EIE77660.1 - 0.19 11.5 2.4 0.61 9.9 1.6 1.9 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.5 EIE77660.1 - 0.56 10.2 2.4 23 5.0 0.1 2.7 2 0 0 2 2 2 0 Zinc ribbon domain DivIVA PF05103.8 EIE77661.1 - 0.0019 18.2 0.9 0.0019 18.2 0.6 1.5 2 0 0 2 2 2 1 DivIVA protein SlyX PF04102.7 EIE77661.1 - 0.03 14.6 2.7 0.03 14.6 1.8 2.8 3 0 0 3 3 3 0 SlyX CENP-F_leu_zip PF10473.4 EIE77661.1 - 0.057 13.2 0.5 0.057 13.2 0.4 2.2 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Mto2_bdg PF12808.2 EIE77661.1 - 2.2 8.4 15.2 0.77 9.9 1.0 3.4 4 0 0 4 4 4 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Spc24 PF08286.6 EIE77661.1 - 2.8 7.6 8.0 24 4.6 5.5 2.3 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 DUF3450 PF11932.3 EIE77661.1 - 3.1 7.0 15.2 29 3.7 10.5 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) Fib_alpha PF08702.5 EIE77661.1 - 4 7.5 9.8 0.99 9.5 1.0 2.4 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF4140 PF13600.1 EIE77661.1 - 6.5 7.2 9.9 5.5 7.4 0.4 2.6 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF972 PF06156.8 EIE77661.1 - 7.6 6.9 6.8 35 4.8 4.7 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF972) RVT_1 PF00078.22 EIE77662.1 - 1.8e-18 66.6 0.0 3.4e-18 65.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Arrestin_C PF02752.17 EIE77664.1 - 3.7e-11 43.2 8.1 4.2e-10 39.8 1.1 3.2 3 0 0 3 3 3 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EIE77664.1 - 4e-09 36.4 0.8 6e-05 22.8 0.0 3.4 2 1 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Exo_endo_phos PF03372.18 EIE77666.1 - 2.8e-05 24.1 0.0 2.9e-05 24.1 0.0 1.0 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF1212 PF06738.7 EIE77667.1 - 8.3e-33 113.4 10.8 3.4e-28 98.4 0.2 2.8 2 1 0 2 2 2 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 EIE77667.1 - 5e-13 49.1 23.8 7.2e-13 48.6 7.1 2.5 2 1 0 2 2 2 2 Protein of unknown function (DUF3815) Kelch_4 PF13418.1 EIE77668.1 - 1.9e-20 72.3 8.9 0.00011 21.8 0.0 6.6 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.1 EIE77668.1 - 9e-18 63.6 9.6 0.0015 18.6 0.0 6.6 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.1 EIE77668.1 - 3e-17 62.2 11.8 0.00032 20.7 0.0 6.1 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.1 EIE77668.1 - 5.9e-16 58.0 8.8 0.0054 16.6 0.0 6.3 6 0 0 6 6 6 4 Kelch motif Kelch_1 PF01344.20 EIE77668.1 - 3.4e-15 55.2 3.6 0.0017 17.8 0.0 5.8 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.10 EIE77668.1 - 1.1e-12 47.1 8.2 0.0016 18.0 0.0 8.0 8 1 0 8 8 8 3 Kelch motif CTP_transf_2 PF01467.21 EIE77668.1 - 0.00061 19.8 0.0 0.0017 18.4 0.0 1.8 2 0 0 2 2 2 1 Cytidylyltransferase YqhR PF11085.3 EIE77668.1 - 0.022 14.2 0.2 0.022 14.2 0.2 2.0 2 0 0 2 2 2 0 Conserved membrane protein YqhR DUF4131 PF13567.1 EIE77668.1 - 0.64 9.4 5.7 0.077 12.3 0.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DDE_3 PF13358.1 EIE77669.1 - 0.00045 19.9 0.0 0.00061 19.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Synaptobrevin PF00957.16 EIE77670.1 - 1.7e-26 91.6 0.2 1.9e-26 91.4 0.2 1.0 1 0 0 1 1 1 1 Synaptobrevin ETRAMP PF09716.5 EIE77670.1 - 0.0012 18.6 0.0 0.0012 18.6 0.0 1.2 1 0 0 1 1 1 1 Malarial early transcribed membrane protein (ETRAMP) TauE PF01925.14 EIE77670.1 - 0.03 13.7 0.2 0.034 13.5 0.1 1.1 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE DUF2077 PF09850.4 EIE77670.1 - 0.052 12.9 0.0 0.058 12.8 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2077) PAXNEB PF05625.6 EIE77671.1 - 6.2e-88 295.0 0.0 7.7e-88 294.7 0.0 1.1 1 0 0 1 1 1 1 PAXNEB protein KaiC PF06745.8 EIE77671.1 - 2.8e-05 23.3 0.0 0.00021 20.5 0.0 2.1 2 1 0 2 2 2 1 KaiC Ribosomal_S22 PF08136.6 EIE77671.1 - 0.071 13.2 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 30S ribosomal protein subunit S22 family SNF2_N PF00176.18 EIE77672.1 - 1.4e-77 260.4 1.5 1.4e-77 260.4 1.1 2.3 2 0 0 2 2 2 1 SNF2 family N-terminal domain Chromo PF00385.19 EIE77672.1 - 3.6e-20 71.3 9.2 2.1e-10 40.1 1.9 3.7 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 EIE77672.1 - 3.2e-17 62.1 0.0 8.9e-17 60.7 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4208 PF13907.1 EIE77672.1 - 3.4e-11 43.2 0.5 3.4e-11 43.2 0.3 3.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) HTH_Tnp_IS630 PF01710.11 EIE77673.1 - 0.048 13.3 0.0 0.09 12.4 0.0 1.5 1 0 0 1 1 1 0 Transposase HTH_23 PF13384.1 EIE77673.1 - 0.14 11.8 0.0 0.35 10.5 0.0 1.6 2 0 0 2 2 2 0 Homeodomain-like domain Ribosomal_S25 PF03297.10 EIE77674.1 - 8.7e-37 125.3 0.7 1e-36 125.1 0.5 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_24 PF13412.1 EIE77674.1 - 0.0075 15.6 0.4 0.011 15.1 0.3 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.2 EIE77674.1 - 0.032 13.8 0.0 0.035 13.7 0.0 1.2 1 0 0 1 1 1 0 MarR family LRR_4 PF12799.2 EIE77675.1 - 9e-18 63.4 8.4 5.4e-05 22.7 0.0 4.1 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EIE77675.1 - 2.8e-15 55.8 5.6 1.8e-09 37.2 2.8 3.0 2 0 0 2 2 2 2 Leucine rich repeat Acyltransferase PF01553.16 EIE77675.1 - 2.8e-12 46.2 0.0 6.9e-06 25.5 0.0 2.8 3 0 0 3 3 3 2 Acyltransferase LRR_1 PF00560.28 EIE77675.1 - 2.6e-07 29.7 9.4 1.5 9.1 0.1 6.3 5 1 0 5 5 5 3 Leucine Rich Repeat LRR_7 PF13504.1 EIE77675.1 - 1.3e-05 24.5 5.3 10 6.8 0.0 5.9 5 0 0 5 5 5 2 Leucine rich repeat LRR_6 PF13516.1 EIE77675.1 - 0.00097 18.9 10.4 0.16 12.1 0.3 5.5 4 1 1 5 5 5 1 Leucine Rich repeat DUF498 PF04430.9 EIE77676.1 - 3.8e-28 97.2 0.0 4.6e-28 96.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Vac_ImportDeg PF09783.4 EIE77677.1 - 2.6e-11 43.3 0.2 7.2e-11 41.9 0.0 1.7 2 0 0 2 2 2 1 Vacuolar import and degradation protein GCV_H PF01597.14 EIE77678.1 - 0.00019 21.1 0.0 0.00025 20.7 0.0 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Pox_A32 PF04665.7 EIE77679.1 - 0.054 12.7 0.0 0.075 12.3 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein FtsK_SpoIIIE PF01580.13 EIE77679.1 - 0.082 12.3 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family BCAS3 PF12490.3 EIE77680.1 - 2.9e-12 46.4 3.0 4.3e-09 36.0 0.1 3.3 3 1 1 4 4 4 2 Breast carcinoma amplified sequence 3 WD40 PF00400.27 EIE77680.1 - 8.5e-06 25.4 0.6 8.5e-06 25.4 0.4 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat Mito_carr PF00153.22 EIE77681.1 - 1.4e-46 156.1 4.0 2.4e-15 55.9 0.4 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein FAD_binding_1 PF00667.15 EIE77682.1 - 1.2e-63 214.4 0.0 2.3e-63 213.5 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain POR_N PF01855.14 EIE77682.1 - 4.2e-25 88.6 0.9 7.1e-25 87.8 0.6 1.4 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg NAD_binding_1 PF00175.16 EIE77682.1 - 2e-14 54.0 0.0 1.1e-13 51.7 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain POR PF01558.13 EIE77682.1 - 0.027 14.4 0.0 0.068 13.0 0.0 1.7 1 0 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase FAD_binding_6 PF00970.19 EIE77682.1 - 0.035 14.2 0.0 0.18 11.9 0.0 2.2 2 0 0 2 2 2 0 Oxidoreductase FAD-binding domain Myc_N PF01056.13 EIE77684.1 - 0.064 12.4 1.0 0.075 12.1 0.7 1.1 1 0 0 1 1 1 0 Myc amino-terminal region WD40 PF00400.27 EIE77688.1 - 2.8e-58 191.8 18.1 3.1e-08 33.1 0.0 11.6 12 0 0 12 12 12 9 WD domain, G-beta repeat eIF2A PF08662.6 EIE77688.1 - 2.2e-12 47.0 2.7 8e-05 22.4 0.1 4.1 2 2 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A BBS2_Mid PF14783.1 EIE77688.1 - 0.0055 16.4 3.3 1.6 8.5 0.0 4.5 6 1 1 7 7 7 2 Ciliary BBSome complex subunit 2, middle region Str_synth PF03088.11 EIE77688.1 - 0.079 13.0 0.0 8 6.5 0.0 3.5 2 1 1 3 3 3 0 Strictosidine synthase PQQ_3 PF13570.1 EIE77688.1 - 0.9 9.9 11.0 24 5.3 0.0 5.9 6 1 0 6 6 6 0 PQQ-like domain SMC_N PF02463.14 EIE77689.1 - 3.6e-65 219.2 15.1 1.3e-63 214.1 10.5 2.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EIE77689.1 - 1.1e-17 64.0 0.0 3.3e-17 62.5 0.0 1.9 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 EIE77689.1 - 5.4e-14 52.9 16.3 5.4e-14 52.9 11.3 6.7 2 2 1 3 3 3 1 AAA domain AAA_21 PF13304.1 EIE77689.1 - 2.2e-09 37.7 28.7 7.1e-06 26.1 0.1 5.5 4 1 0 5 5 5 3 AAA domain ADIP PF11559.3 EIE77689.1 - 7.1e-05 22.7 9.4 7.1e-05 22.7 6.5 9.3 4 3 4 9 9 9 2 Afadin- and alpha -actinin-Binding Reo_sigmaC PF04582.7 EIE77689.1 - 0.00019 20.7 39.5 0.0034 16.6 3.9 6.2 2 2 3 6 6 6 4 Reovirus sigma C capsid protein AAA_29 PF13555.1 EIE77689.1 - 0.00023 20.6 0.0 0.00064 19.1 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain TPR_MLP1_2 PF07926.7 EIE77689.1 - 0.00035 20.3 16.8 0.00035 20.3 11.6 8.1 2 2 4 6 6 6 1 TPR/MLP1/MLP2-like protein NPV_P10 PF05531.7 EIE77689.1 - 0.0044 17.2 52.1 0.47 10.7 0.9 8.9 7 3 2 9 9 9 4 Nucleopolyhedrovirus P10 protein Filament PF00038.16 EIE77689.1 - 7 6.0 99.9 0.39 10.1 2.7 7.0 2 2 3 5 5 5 0 Intermediate filament protein JAB PF01398.16 EIE77692.1 - 6.7e-16 58.0 0.0 1.8e-15 56.6 0.0 1.7 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease zf-H2C2_2 PF13465.1 EIE77693.1 - 3.1e-19 68.2 15.9 1.4e-07 31.4 0.4 4.3 4 0 0 4 4 4 4 Zinc-finger double domain zf-C2H2 PF00096.21 EIE77693.1 - 2e-13 49.7 23.0 4.6e-05 23.5 1.8 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIE77693.1 - 2.2e-08 33.8 19.7 0.0015 18.7 0.8 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EIE77693.1 - 0.33 11.1 12.1 1.4 9.1 0.1 3.6 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EIE77693.1 - 0.38 11.0 9.9 2.2 8.5 0.3 3.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type RPAP2_Rtr1 PF04181.8 EIE77693.1 - 0.45 10.6 5.9 2.8 8.1 0.0 2.9 1 1 1 2 2 2 0 Rtr1/RPAP2 family zf-TRAF PF02176.13 EIE77693.1 - 0.6 10.5 9.5 2.1 8.7 2.3 2.3 1 1 1 2 2 2 0 TRAF-type zinc finger zf-BED PF02892.10 EIE77693.1 - 1.8 8.4 6.6 0.92 9.3 0.8 2.6 2 0 0 2 2 2 0 BED zinc finger CHORD PF04968.7 EIE77693.1 - 2.4 8.4 8.0 17 5.7 2.8 2.8 2 1 0 2 2 2 0 CHORD DUF3591 PF12157.3 EIE77694.1 - 4.8e-171 569.1 0.2 2.5e-170 566.8 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3591) TBP-binding PF09247.6 EIE77694.1 - 1.9e-10 40.7 0.2 7.5e-10 38.8 0.1 2.1 1 0 0 1 1 1 1 TATA box-binding protein binding zf-CCHC_6 PF15288.1 EIE77694.1 - 1e-05 25.0 1.2 2.4e-05 23.9 0.8 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EIE77694.1 - 0.83 9.7 3.5 1.9 8.5 2.4 1.6 1 0 0 1 1 1 0 Zinc knuckle MFS_1 PF07690.11 EIE77695.1 - 5.4e-34 117.4 30.0 1.2e-30 106.3 18.4 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIE77695.1 - 1.8e-08 33.4 6.6 1.8e-08 33.4 4.6 3.4 3 1 0 4 4 4 2 Sugar (and other) transporter SPC25 PF06703.6 EIE77695.1 - 1.5 8.3 4.5 10 5.6 0.5 2.6 3 0 0 3 3 3 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Pkinase PF00069.20 EIE77696.1 - 1.2e-62 211.4 0.0 1.5e-62 211.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE77696.1 - 1.2e-31 109.7 0.0 1.7e-31 109.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE77696.1 - 1.5e-06 27.4 0.0 3.6e-06 26.1 0.0 1.7 1 1 0 1 1 1 1 Kinase-like DDE_3 PF13358.1 EIE77700.1 - 1e-06 28.5 0.0 1e-06 28.5 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Exo_endo_phos PF03372.18 EIE77701.1 - 9.4e-18 65.0 0.0 1.4e-17 64.4 0.0 1.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Glucosamine_iso PF01182.15 EIE77702.1 - 7.6e-24 84.5 0.0 1.1e-23 83.9 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase IDO PF01231.13 EIE77703.1 - 1.4e-52 178.5 0.0 1.9e-52 178.1 0.0 1.1 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DivIC PF04977.10 EIE77704.1 - 0.0048 16.3 0.6 0.0095 15.4 0.4 1.4 1 0 0 1 1 1 1 Septum formation initiator SlyX PF04102.7 EIE77704.1 - 0.062 13.6 0.3 0.062 13.6 0.2 1.7 2 0 0 2 2 2 0 SlyX TMF_TATA_bd PF12325.3 EIE77704.1 - 0.15 11.7 0.5 0.34 10.6 0.2 1.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Gag_spuma PF03276.9 EIE77704.1 - 0.94 7.7 9.1 1.2 7.3 6.3 1.1 1 0 0 1 1 1 0 Spumavirus gag protein zf-MYND PF01753.13 EIE77706.1 - 0.00079 19.2 17.3 0.00079 19.2 12.0 2.2 2 0 0 2 2 2 1 MYND finger SET PF00856.23 EIE77706.1 - 0.0054 17.0 0.0 0.012 15.8 0.0 1.6 1 0 0 1 1 1 1 SET domain PALP PF00291.20 EIE77707.1 - 1.6e-71 241.0 0.9 2e-71 240.7 0.6 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF2325 PF10087.4 EIE77707.1 - 0.031 14.0 0.1 15 5.5 0.0 2.8 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2325) ANF_receptor PF01094.23 EIE77708.1 - 8.6e-32 110.2 1.1 1.2e-31 109.8 0.8 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.17 EIE77708.1 - 2e-25 89.5 27.8 2.9e-25 89.0 19.3 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Peripla_BP_6 PF13458.1 EIE77708.1 - 1.5e-10 40.9 0.1 2.4e-10 40.2 0.1 1.2 1 0 0 1 1 1 1 Periplasmic binding protein PH_9 PF15410.1 EIE77708.1 - 0.0035 17.4 0.2 0.0035 17.4 0.2 2.2 3 0 0 3 3 3 1 Pleckstrin homology domain Ank PF00023.25 EIE77710.1 - 1.4e-30 103.5 0.9 2e-07 30.4 0.0 4.6 4 0 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.2 EIE77710.1 - 7.1e-29 100.0 0.9 1.8e-14 53.7 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EIE77710.1 - 1.4e-28 98.7 4.7 1.2e-09 38.3 0.2 4.5 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 EIE77710.1 - 2e-24 85.0 2.7 8.8e-10 38.5 0.1 4.5 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIE77710.1 - 8.7e-23 78.1 4.1 7.8e-06 25.6 0.2 4.9 5 0 0 5 5 5 4 Ankyrin repeat FYVE PF01363.16 EIE77710.1 - 2.3e-18 65.8 6.1 4.2e-18 64.9 4.2 1.4 1 0 0 1 1 1 1 FYVE zinc finger MIT PF04212.13 EIE77710.1 - 0.013 15.3 0.3 0.032 14.0 0.2 1.8 1 1 0 1 1 1 0 MIT (microtubule interacting and transport) domain FYVE_2 PF02318.11 EIE77710.1 - 0.31 10.9 5.4 0.14 12.1 1.8 1.8 2 0 0 2 2 2 0 FYVE-type zinc finger DUF2296 PF10058.4 EIE77710.1 - 0.42 10.3 0.0 0.42 10.3 0.0 2.5 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) DUF1168 PF06658.7 EIE77711.1 - 1.1e-37 128.7 32.4 1.5e-37 128.2 22.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) SprA-related PF12118.3 EIE77711.1 - 0.023 14.0 19.5 0.025 13.9 13.5 1.2 1 0 0 1 1 1 0 SprA-related family Atg14 PF10186.4 EIE77711.1 - 0.72 8.7 16.0 0.77 8.6 11.1 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 GAGA_bind PF06217.7 EIE77711.1 - 0.79 9.6 17.4 0.81 9.5 12.0 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family CAF-1_p150 PF11600.3 EIE77711.1 - 0.84 8.9 53.4 0.2 10.9 35.1 1.4 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Hid1 PF12722.2 EIE77711.1 - 3.8 5.0 13.4 3.4 5.2 9.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ycf1 PF05758.7 EIE77711.1 - 4.5 4.8 18.1 4.7 4.8 12.5 1.1 1 0 0 1 1 1 0 Ycf1 DDE_3 PF13358.1 EIE77712.1 - 6.5e-16 58.3 0.0 9.2e-16 57.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_ISAZ013 PF07592.6 EIE77712.1 - 0.0024 16.6 0.0 0.0025 16.5 0.0 1.1 1 0 0 1 1 1 1 Rhodopirellula transposase DDE domain DDE_1 PF03184.14 EIE77712.1 - 0.015 14.4 0.1 0.017 14.2 0.1 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease DUF2036 PF09724.4 EIE77712.1 - 0.069 12.2 0.0 0.069 12.2 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2036) V-ATPase_H_C PF11698.3 EIE77712.1 - 0.19 11.6 1.0 0.66 9.8 0.7 2.0 1 1 0 1 1 1 0 V-ATPase subunit H RFC1 PF08519.7 EIE77714.1 - 1.6e-48 164.3 3.9 1.9e-46 157.6 0.0 2.8 3 0 0 3 3 3 2 Replication factor RFC1 C terminal domain BRCT PF00533.21 EIE77714.1 - 1.2e-09 38.2 0.1 5.4e-09 36.0 0.0 2.2 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 EIE77714.1 - 5.1e-09 36.4 0.0 8.7e-07 29.1 0.0 3.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EIE77714.1 - 0.0001 22.0 0.0 0.00029 20.5 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 EIE77714.1 - 0.00017 20.7 0.0 0.00051 19.1 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EIE77714.1 - 0.0009 20.0 0.9 0.0036 18.1 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EIE77714.1 - 0.0046 17.1 0.2 0.069 13.2 0.0 2.9 2 2 1 3 3 3 1 AAA domain AAA_33 PF13671.1 EIE77714.1 - 0.014 15.2 0.0 0.044 13.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EIE77714.1 - 0.016 15.2 0.0 0.058 13.3 0.0 1.9 1 1 1 2 2 2 0 AAA ATPase domain PTCB-BRCT PF12738.2 EIE77714.1 - 0.047 13.5 0.1 0.17 11.7 0.1 2.0 1 0 0 1 1 1 0 twin BRCT domain NACHT PF05729.7 EIE77714.1 - 0.11 12.0 0.0 1.3 8.6 0.0 2.5 2 0 0 2 2 2 0 NACHT domain DDE_1 PF03184.14 EIE77716.1 - 8.7e-24 83.8 0.9 1.7e-23 82.8 0.6 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EIE77716.1 - 0.00076 19.2 0.0 0.0022 17.7 0.0 1.8 1 1 0 1 1 1 1 DDE superfamily endonuclease DUF2346 PF09803.4 EIE77716.1 - 0.11 12.4 2.2 0.12 12.2 0.4 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2346) DUF3306 PF11748.3 EIE77717.1 - 0.011 16.3 1.5 0.021 15.4 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) DUF2360 PF10152.4 EIE77717.1 - 0.13 12.5 3.7 1.1 9.5 0.2 2.1 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) SPX PF03105.14 EIE77717.1 - 0.31 10.7 11.2 0.4 10.4 7.8 1.1 1 0 0 1 1 1 0 SPX domain DUF1675 PF07897.6 EIE77717.1 - 0.6 9.9 7.0 0.76 9.5 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Carb_kinase PF01256.12 EIE77719.1 - 2.7e-40 138.1 1.2 5.1e-25 88.1 0.0 2.2 1 1 1 2 2 2 2 Carbohydrate kinase HK PF02110.10 EIE77719.1 - 0.0066 15.6 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family Phos_pyr_kin PF08543.7 EIE77719.1 - 0.049 12.8 0.2 0.31 10.1 0.0 2.1 2 1 1 3 3 3 0 Phosphomethylpyrimidine kinase zf-H2C2_2 PF13465.1 EIE77721.1 - 2.5e-05 24.3 1.2 0.0005 20.2 0.2 2.7 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.21 EIE77721.1 - 0.088 13.1 2.7 4.5 7.8 0.0 2.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type PigN PF04987.9 EIE77723.1 - 5.8e-25 87.8 9.6 7.9e-25 87.3 6.7 1.1 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 EIE77723.1 - 9.7e-15 54.7 0.0 5.7e-08 32.4 0.0 2.1 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EIE77723.1 - 3.8e-07 29.6 0.0 1.6e-06 27.5 0.0 1.8 1 1 0 2 2 2 1 Sulfatase Metalloenzyme PF01676.13 EIE77723.1 - 0.00042 19.7 0.0 0.0014 18.0 0.0 1.9 2 1 0 2 2 2 1 Metalloenzyme superfamily Hist_deacetyl PF00850.14 EIE77724.1 - 8.6e-66 222.3 0.0 1.5e-62 211.6 0.0 2.4 1 1 0 1 1 1 1 Histone deacetylase domain ABC2_membrane PF01061.19 EIE77725.1 - 5e-39 133.6 25.1 5e-39 133.6 17.4 1.6 2 0 0 2 2 1 1 ABC-2 type transporter ABC_tran PF00005.22 EIE77725.1 - 2e-29 102.6 0.0 3.3e-29 101.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EIE77725.1 - 5.6e-11 42.9 0.0 2.3e-10 40.9 0.0 2.1 2 1 0 2 2 1 1 AAA domain ABC2_membrane_3 PF12698.2 EIE77725.1 - 7.4e-06 25.2 26.0 7.4e-06 25.2 18.0 2.0 2 1 0 2 2 2 1 ABC-2 family transporter protein AAA_25 PF13481.1 EIE77725.1 - 1.1e-05 24.8 0.0 0.0017 17.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.1 EIE77725.1 - 4e-05 22.8 0.0 0.19 10.7 0.1 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 EIE77725.1 - 0.00033 21.4 0.0 0.00064 20.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EIE77725.1 - 0.00045 19.4 0.1 0.0008 18.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EIE77725.1 - 0.0014 18.1 0.1 0.0031 16.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 EIE77725.1 - 0.0015 18.5 0.0 0.0033 17.4 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 EIE77725.1 - 0.0016 18.3 0.0 0.0059 16.5 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_18 PF13238.1 EIE77725.1 - 0.0033 17.7 0.0 0.0067 16.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EIE77725.1 - 0.0087 15.7 0.2 0.015 14.9 0.1 1.3 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EIE77725.1 - 0.011 15.9 0.1 0.024 14.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EIE77725.1 - 0.011 15.4 0.1 0.034 13.8 0.0 1.8 2 0 0 2 2 1 0 Part of AAA domain AAA_28 PF13521.1 EIE77725.1 - 0.012 15.5 0.2 0.022 14.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.20 EIE77725.1 - 0.017 14.6 0.1 0.027 13.9 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain UPF0079 PF02367.12 EIE77725.1 - 0.026 14.1 0.3 0.052 13.1 0.2 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 SMC_N PF02463.14 EIE77725.1 - 0.027 13.6 0.0 0.67 9.1 0.0 2.2 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain Arch_ATPase PF01637.13 EIE77725.1 - 0.037 13.7 0.0 0.064 12.9 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase MobB PF03205.9 EIE77725.1 - 0.044 13.4 0.1 0.082 12.6 0.1 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 EIE77725.1 - 0.058 12.8 0.1 0.11 11.9 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.1 EIE77725.1 - 0.1 12.1 0.2 0.18 11.3 0.1 1.2 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.15 EIE77725.1 - 0.11 12.2 0.1 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase SbcCD_C PF13558.1 EIE77725.1 - 0.12 12.3 0.0 0.47 10.4 0.0 2.1 2 1 0 2 2 1 0 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.1 EIE77725.1 - 0.17 11.7 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EIE77725.1 - 0.27 10.0 0.3 0.49 9.1 0.2 1.3 1 0 0 1 1 1 0 NB-ARC domain Abhydrolase_1 PF00561.15 EIE77726.1 - 3.9e-13 49.4 0.0 4.2e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EIE77726.1 - 1.9e-12 47.5 0.0 2e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIE77726.1 - 7.6e-08 32.2 0.0 9.4e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EIE77726.1 - 3.8e-07 29.7 0.0 4.8e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Ndr PF03096.9 EIE77726.1 - 0.00025 19.6 0.0 0.00035 19.1 0.0 1.2 1 0 0 1 1 1 1 Ndr family Lipase_3 PF01764.20 EIE77726.1 - 0.00029 20.4 0.0 0.00043 19.9 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_3 PF07859.8 EIE77726.1 - 0.00036 20.1 0.0 0.00055 19.5 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold UPF0227 PF05728.7 EIE77726.1 - 0.00057 19.6 0.0 0.0008 19.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) DUF2048 PF09752.4 EIE77726.1 - 0.014 14.2 0.0 0.016 14.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) BAAT_C PF08840.6 EIE77726.1 - 0.019 14.6 0.0 0.026 14.2 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF915 PF06028.6 EIE77726.1 - 0.063 12.3 0.1 0.093 11.8 0.1 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Thioesterase PF00975.15 EIE77726.1 - 0.078 13.1 0.0 0.09 12.9 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Chlorophyllase2 PF12740.2 EIE77726.1 - 0.11 11.4 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme DUF2305 PF10230.4 EIE77726.1 - 0.15 11.4 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) XkdW PF09636.5 EIE77727.1 - 0.052 13.4 0.1 0.17 11.8 0.0 1.9 2 0 0 2 2 2 0 XkdW protein Rapsyn_N PF10579.4 EIE77727.1 - 0.088 12.6 0.0 0.26 11.1 0.0 1.7 1 0 0 1 1 1 0 Rapsyn N-terminal myristoylation and linker region TAF PF02969.12 EIE77728.1 - 1.6e-05 24.7 0.3 3.4e-05 23.6 0.2 1.6 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.19 EIE77728.1 - 0.082 13.0 0.8 1.5 8.9 0.2 2.5 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 Ribosomal_L27e PF01777.13 EIE77729.1 - 2.8e-37 126.6 7.1 4.3e-37 126.0 4.9 1.3 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 EIE77729.1 - 3e-05 23.5 1.5 8e-05 22.2 1.1 1.8 1 0 0 1 1 1 1 KOW motif RRM_1 PF00076.17 EIE77730.1 - 2.7e-07 30.1 0.1 7.2e-07 28.7 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE77730.1 - 1.3e-05 25.0 0.0 3.4e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Suf PF05843.9 EIE77730.1 - 0.00069 19.4 1.5 0.00069 19.4 1.0 1.5 2 0 0 2 2 2 1 Suppressor of forked protein (Suf) RRM_5 PF13893.1 EIE77730.1 - 0.0077 16.0 0.1 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1943 PF09172.6 EIE77730.1 - 2.1 7.1 9.6 1.6 7.5 5.7 1.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1943) Spt5_N PF11942.3 EIE77730.1 - 3.9 8.1 8.8 1.7 9.3 4.4 1.6 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Vps39_2 PF10367.4 EIE77731.1 - 7.9e-34 116.1 0.3 1.6e-32 111.9 0.0 2.9 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.17 EIE77731.1 - 3.5e-29 102.0 0.0 6.3e-29 101.2 0.0 1.4 1 0 0 1 1 1 1 CNH domain Vps39_1 PF10366.4 EIE77731.1 - 2.4e-17 62.9 4.8 1.6e-14 53.8 0.1 4.7 5 1 0 5 5 5 1 Vacuolar sorting protein 39 domain 1 Clathrin PF00637.15 EIE77731.1 - 5.1e-10 39.1 1.1 5.1e-10 39.1 0.7 3.2 3 0 0 3 3 3 1 Region in Clathrin and VPS TPR_1 PF00515.23 EIE77731.1 - 0.00039 19.9 3.2 0.7 9.6 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EIE77731.1 - 0.0056 17.2 0.3 11 6.9 0.0 4.4 5 0 0 5 5 4 1 Tetratricopeptide repeat Apc3 PF12895.2 EIE77731.1 - 0.011 15.8 1.8 0.065 13.3 0.2 2.6 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 EIE77731.1 - 0.035 14.0 3.8 9.6 6.3 0.2 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EIE77731.1 - 0.058 13.2 1.3 0.8 9.6 0.1 3.4 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.1 EIE77731.1 - 0.1 12.9 2.8 0.32 11.3 0.3 3.0 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 EIE77731.1 - 0.1 12.5 3.9 1.9 8.4 0.3 3.4 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 EIE77731.1 - 0.14 12.8 0.3 6.8 7.5 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 EIE77731.1 - 0.25 11.0 4.1 14 5.4 0.2 4.1 4 1 1 5 5 5 0 TPR repeat SRR PF07709.6 EIE77732.1 - 0.079 13.1 1.6 15 6.2 0.1 3.0 2 0 0 2 2 2 0 Seven Residue Repeat MCPsignal PF00015.16 EIE77732.1 - 0.082 12.4 13.0 1.1 8.7 2.1 2.1 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Reo_sigmaC PF04582.7 EIE77732.1 - 0.25 10.4 4.7 3.1 6.8 0.5 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein PLA2G12 PF06951.6 EIE77732.1 - 0.26 10.8 0.1 0.26 10.8 0.1 2.3 3 0 0 3 3 3 0 Group XII secretory phospholipase A2 precursor (PLA2G12) ATG16 PF08614.6 EIE77732.1 - 0.27 11.0 34.3 13 5.5 6.8 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF812 PF05667.6 EIE77732.1 - 0.32 9.4 32.1 1.1 7.7 13.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF812) Stanniocalcin PF03298.8 EIE77732.1 - 0.47 9.4 8.6 0.034 13.1 2.6 1.5 2 0 0 2 2 2 0 Stanniocalcin family DUF745 PF05335.8 EIE77732.1 - 0.59 9.6 27.0 0.22 11.0 11.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF745) AAA_13 PF13166.1 EIE77732.1 - 0.98 7.8 29.3 2.8 6.2 20.3 1.7 1 1 0 1 1 1 0 AAA domain DUF724 PF05266.9 EIE77732.1 - 1.4 8.4 30.4 0.86 9.1 1.7 2.7 1 1 3 4 4 4 0 Protein of unknown function (DUF724) GAS PF13851.1 EIE77732.1 - 1.5 7.9 38.9 0.8 8.8 16.3 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Glutaredoxin2_C PF04399.8 EIE77732.1 - 1.7 8.1 13.8 0.62 9.6 1.1 3.3 1 1 1 3 3 3 0 Glutaredoxin 2, C terminal domain ADIP PF11559.3 EIE77732.1 - 3.2 7.6 36.3 0.91 9.4 10.8 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.4 EIE77732.1 - 3.9 7.3 37.8 6.1 6.6 13.3 3.0 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FliJ PF02050.11 EIE77732.1 - 6.1 6.9 45.6 0.31 11.0 9.2 2.7 1 1 1 2 2 2 0 Flagellar FliJ protein TMF_DNA_bd PF12329.3 EIE77732.1 - 6.2 6.7 33.5 4.7 7.0 6.5 3.5 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding TPR_MLP1_2 PF07926.7 EIE77732.1 - 6.2 6.5 40.2 4.5 7.0 21.0 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Cauli_AT PF03233.8 EIE77732.1 - 8.7 6.0 18.7 7.6 6.2 3.6 2.5 1 1 2 3 3 3 0 Aphid transmission protein Sel1 PF08238.7 EIE77733.1 - 1.2e-05 25.7 0.9 0.24 12.1 0.2 3.2 3 0 0 3 3 3 2 Sel1 repeat DUF1358 PF07096.6 EIE77734.1 - 0.012 15.3 0.6 0.024 14.3 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1358) DUF1469 PF07332.6 EIE77734.1 - 0.069 12.8 0.7 3.1 7.5 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) Reprolysin_4 PF13583.1 EIE77736.1 - 4.1e-44 150.5 2.1 7.2e-44 149.7 1.5 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EIE77736.1 - 4.4e-43 147.5 7.9 1.1e-42 146.1 5.4 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 EIE77736.1 - 3.9e-36 124.7 4.8 1e-35 123.3 3.3 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 EIE77736.1 - 1.4e-19 70.7 0.3 1.4e-19 70.7 0.2 2.7 3 0 0 3 3 3 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.18 EIE77736.1 - 5.3e-12 45.7 15.3 5.3e-12 45.7 10.6 4.4 3 1 1 4 4 4 1 Disintegrin Reprolysin PF01421.14 EIE77736.1 - 5.8e-05 22.7 11.9 0.0017 17.9 8.3 2.8 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.14 EIE77736.1 - 0.00011 21.9 0.0 0.00022 21.0 0.0 1.4 1 0 0 1 1 1 1 Reprolysin family propeptide GP41 PF00517.12 EIE77736.1 - 0.0048 16.4 0.0 0.012 15.1 0.0 1.6 1 0 0 1 1 1 1 Retroviral envelope protein WD40 PF00400.27 EIE77737.1 - 5.4e-35 118.0 8.4 1.2e-11 44.0 0.1 7.6 7 0 0 7 7 7 5 WD domain, G-beta repeat zf-CCCH PF00642.19 EIE77737.1 - 5.7e-22 76.9 9.4 6.4e-11 41.6 0.5 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EIE77737.1 - 2.9e-05 23.8 4.4 0.043 13.8 0.2 2.9 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type PQQ_2 PF13360.1 EIE77737.1 - 7.9e-05 22.2 0.0 0.00044 19.7 0.0 2.1 2 1 0 2 2 2 1 PQQ-like domain PQQ PF01011.16 EIE77737.1 - 0.0094 15.4 0.0 0.51 9.9 0.0 2.9 3 0 0 3 3 3 1 PQQ enzyme repeat Peptidase_M36 PF02128.10 EIE77738.1 - 1.2e-141 471.9 11.1 1.6e-141 471.5 7.7 1.2 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.8 EIE77738.1 - 1.6e-11 43.4 0.9 1.6e-11 43.4 0.6 2.1 2 0 0 2 2 2 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4_C PF02868.10 EIE77738.1 - 2.7e-05 23.9 0.0 6.8e-05 22.6 0.0 1.7 1 1 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain YycI PF09648.5 EIE77738.1 - 0.017 14.6 1.2 0.033 13.6 0.0 2.0 2 0 0 2 2 2 0 YycH protein DUF3550 PF12070.3 EIE77739.1 - 2.6e-51 174.9 0.9 2.4e-33 115.6 0.1 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3550/UPF0682) zf-RanBP PF00641.13 EIE77740.1 - 7.4e-22 76.1 24.1 2.5e-08 32.8 1.9 3.4 3 0 0 3 3 3 3 Zn-finger in Ran binding protein and others RNase_T PF00929.19 EIE77740.1 - 5.6e-12 46.2 0.5 9.7e-12 45.4 0.1 1.7 2 0 0 2 2 2 1 Exonuclease RRM_1 PF00076.17 EIE77740.1 - 6.6e-08 32.0 0.0 2.4e-07 30.2 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE77740.1 - 7.9e-06 25.7 0.0 2.8e-05 24.0 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE77740.1 - 0.033 14.0 0.0 0.15 11.9 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PGBA_N PF15436.1 EIE77740.1 - 0.058 12.6 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Plasminogen-binding protein pgbA N-terminal DZR PF12773.2 EIE77740.1 - 0.46 10.3 21.8 0.34 10.7 1.6 3.3 2 1 1 3 3 3 0 Double zinc ribbon DUF2365 PF10157.4 EIE77741.1 - 2.1e-08 34.2 2.6 2.4e-08 33.9 1.8 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2365) HAUS5 PF14817.1 EIE77741.1 - 0.0053 15.3 6.3 0.0059 15.2 4.4 1.0 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 5 DUF327 PF03885.8 EIE77741.1 - 0.012 15.4 3.2 0.018 14.9 2.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF327) Sec34 PF04136.10 EIE77741.1 - 0.016 14.9 4.6 0.029 14.0 2.7 1.8 1 1 1 2 2 2 0 Sec34-like family Rsd_AlgQ PF04353.8 EIE77741.1 - 0.051 13.2 2.3 0.13 12.0 1.1 1.7 1 1 1 2 2 2 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ TPR_1 PF00515.23 EIE77741.1 - 0.069 12.7 0.1 0.18 11.4 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat IncA PF04156.9 EIE77741.1 - 0.073 12.6 10.4 0.09 12.3 7.2 1.1 1 0 0 1 1 1 0 IncA protein Snapin_Pallidin PF14712.1 EIE77741.1 - 0.092 13.0 8.7 0.043 14.1 2.1 2.0 1 1 1 2 2 2 0 Snapin/Pallidin CENP-Q PF13094.1 EIE77741.1 - 0.23 11.4 7.5 0.28 11.2 5.2 1.1 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit COG5 PF10392.4 EIE77741.1 - 0.32 10.9 7.0 1.3 9.0 4.4 1.9 1 1 1 2 2 2 0 Golgi transport complex subunit 5 tRNA-synt_His PF13393.1 EIE77741.1 - 0.52 9.3 4.1 0.96 8.4 0.7 1.9 1 1 0 2 2 2 0 Histidyl-tRNA synthetase Syntaxin-6_N PF09177.6 EIE77741.1 - 0.53 10.7 3.9 5.1 7.5 2.7 2.3 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Phage_GP20 PF06810.6 EIE77741.1 - 1.3 8.3 6.0 2.2 7.6 2.9 2.0 1 1 1 2 2 2 0 Phage minor structural protein GP20 NPV_P10 PF05531.7 EIE77741.1 - 2 8.6 4.9 28 5.0 3.4 2.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein KilA-N PF04383.8 EIE77742.1 - 6.7e-05 22.4 0.1 0.00074 19.1 0.0 2.3 1 1 0 1 1 1 1 KilA-N domain FR47 PF08445.5 EIE77743.1 - 4.8e-06 26.2 0.0 8.7e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 EIE77743.1 - 2e-05 24.6 0.1 3.1e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EIE77743.1 - 0.0009 19.2 0.0 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 EIE77743.1 - 0.0057 16.6 0.0 0.0092 15.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EIE77743.1 - 0.035 14.2 0.0 0.05 13.7 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Curto_V3 PF07436.6 EIE77744.1 - 0.15 12.2 0.8 0.16 12.0 0.5 1.1 1 0 0 1 1 1 0 Curtovirus V3 protein Aminotran_1_2 PF00155.16 EIE77745.1 - 3.8e-63 213.6 0.0 4.3e-63 213.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EIE77745.1 - 0.00049 18.4 0.0 0.0039 15.5 0.0 2.0 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme PC4 PF02229.11 EIE77746.1 - 2.7e-18 64.9 0.0 5.3e-18 63.9 0.0 1.5 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) F-protein PF00469.15 EIE77746.1 - 0.36 10.1 4.7 0.49 9.7 3.3 1.1 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef ABC_tran_2 PF12848.2 EIE77746.1 - 0.42 10.4 8.0 0.64 9.8 5.6 1.3 1 0 0 1 1 1 0 ABC transporter YqfQ PF14181.1 EIE77746.1 - 2.4 8.1 7.7 2.8 7.9 5.3 1.2 1 0 0 1 1 1 0 YqfQ-like protein eIF-3c_N PF05470.7 EIE77746.1 - 3.3 5.7 9.4 3.9 5.4 6.5 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Aminotran_3 PF00202.16 EIE77747.1 - 6.8e-101 337.5 0.0 8.6e-101 337.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EIE77747.1 - 0.0058 15.6 0.0 0.0085 15.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Hpt PF01627.18 EIE77748.1 - 3.3e-14 52.6 0.1 5.4e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 Hpt domain BUD22 PF09073.5 EIE77748.1 - 0.38 9.7 7.8 0.44 9.5 5.4 1.2 1 0 0 1 1 1 0 BUD22 Sigma70_ner PF04546.8 EIE77748.1 - 2.4 7.7 11.3 0.95 9.0 5.5 1.8 2 0 0 2 2 2 0 Sigma-70, non-essential region FAM176 PF14851.1 EIE77748.1 - 5.7 6.6 6.0 3.1 7.4 2.7 1.6 2 0 0 2 2 2 0 FAM176 family G-patch PF01585.18 EIE77749.1 - 2.1e-12 46.5 1.0 5.5e-12 45.2 0.7 1.8 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EIE77749.1 - 1.7e-07 31.0 0.3 1.7e-07 31.0 0.2 2.7 3 0 0 3 3 3 1 DExH-box splicing factor binding site Spc7_N PF15402.1 EIE77749.1 - 0.098 10.6 2.5 0.16 9.9 1.7 1.3 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 GPI-anchored PF10342.4 EIE77752.1 - 2.5e-14 53.4 4.1 2.5e-14 53.4 2.8 2.5 1 1 1 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Kei1 PF08552.6 EIE77752.1 - 1.4 8.5 8.3 2.7 7.6 5.7 1.5 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Macoilin PF09726.4 EIE77752.1 - 2.1 6.5 16.8 2.2 6.4 11.7 1.1 1 0 0 1 1 1 0 Transmembrane protein Herpes_UL32 PF06070.6 EIE77752.1 - 7.2 4.9 13.2 7.6 4.8 9.1 1.1 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 Golgin_A5 PF09787.4 EIE77752.1 - 9.9 4.5 14.3 11 4.3 9.9 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 zf-RVT PF13966.1 EIE77754.1 - 0.0056 16.9 0.2 0.0056 16.9 0.1 2.1 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase Arrestin_N PF00339.24 EIE77755.1 - 1.1e-10 41.4 0.0 2.3e-07 30.7 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EIE77755.1 - 9.5e-09 35.4 3.2 1.8e-08 34.5 1.7 1.8 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.2 EIE77755.1 - 0.0011 18.4 0.0 0.0022 17.5 0.0 1.4 1 0 0 1 1 1 1 Arrestin_N terminal like UDPGP PF01704.13 EIE77756.1 - 1e-58 198.8 0.0 1.4e-58 198.3 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 EIE77756.1 - 0.11 12.5 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 MobA-like NTP transferase domain Peptidase_S8 PF00082.17 EIE77757.1 - 7.1e-46 156.6 0.6 1.1e-45 155.9 0.4 1.3 1 0 0 1 1 1 1 Subtilase family PA PF02225.17 EIE77757.1 - 4.3e-07 29.5 0.0 1.2e-06 28.1 0.0 1.7 2 0 0 2 2 2 1 PA domain DUF1034 PF06280.7 EIE77757.1 - 6.4e-07 29.7 0.0 1.6e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) AhpC-TSA PF00578.16 EIE77758.1 - 4e-26 91.1 0.0 6e-26 90.5 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.4 EIE77758.1 - 2.7e-15 55.7 0.1 5.2e-15 54.8 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.5 EIE77758.1 - 2.9e-08 33.3 0.0 4.1e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 Redoxin LRR_6 PF13516.1 EIE77759.1 - 3.2e-09 35.9 15.1 0.03 14.3 0.1 7.9 7 0 0 7 7 7 3 Leucine Rich repeat LRR_1 PF00560.28 EIE77759.1 - 3.2e-08 32.5 13.7 0.94 9.7 0.0 7.8 5 1 1 6 6 6 3 Leucine Rich Repeat LRR_4 PF12799.2 EIE77759.1 - 2.5e-05 23.7 16.2 0.72 9.5 0.0 6.7 5 2 2 7 7 7 4 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EIE77759.1 - 0.0036 17.2 16.5 0.66 10.4 0.1 7.3 7 1 0 7 7 7 1 Leucine rich repeat TPR_12 PF13424.1 EIE77760.1 - 3.3e-05 23.7 1.5 0.00084 19.2 0.1 3.1 2 2 1 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EIE77760.1 - 0.00017 21.2 1.0 0.037 13.9 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 EIE77760.1 - 0.00033 20.2 3.6 0.00035 20.1 0.2 2.6 3 1 0 3 3 3 1 TPR repeat Apc3 PF12895.2 EIE77760.1 - 0.0037 17.3 4.2 0.0074 16.4 2.5 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 EIE77760.1 - 0.0082 15.7 0.1 0.0082 15.7 0.0 4.0 6 0 0 6 6 6 2 Tetratricopeptide repeat Matrix PF00661.16 EIE77761.1 - 0.05 11.9 0.3 0.06 11.6 0.2 1.2 1 0 0 1 1 1 0 Viral matrix protein MULE PF10551.4 EIE77763.1 - 6.8e-18 64.6 0.0 1.5e-17 63.5 0.0 1.5 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 EIE77763.1 - 0.02 13.4 0.0 0.021 13.3 0.0 1.1 1 0 0 1 1 1 0 Transposase, Mutator family DUF3453 PF11935.3 EIE77763.1 - 0.096 12.0 0.1 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3453) DUF904 PF06005.7 EIE77766.1 - 0.0022 18.2 0.2 0.004 17.4 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF904) Rab5-bind PF09311.6 EIE77766.1 - 0.0023 17.8 1.0 0.0038 17.1 0.7 1.2 1 0 0 1 1 1 1 Rabaptin-like protein DivIC PF04977.10 EIE77766.1 - 0.15 11.5 3.3 0.26 10.7 2.3 1.3 1 0 0 1 1 1 0 Septum formation initiator CASP_C PF08172.7 EIE77766.1 - 0.21 10.5 2.2 0.29 10.1 1.5 1.2 1 0 0 1 1 1 0 CASP C terminal CCDC144C PF14915.1 EIE77766.1 - 0.5 9.2 3.8 0.68 8.7 2.7 1.1 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region DUF4140 PF13600.1 EIE77766.1 - 0.65 10.4 2.8 1.2 9.6 2.0 1.4 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DOT1 PF08123.8 EIE77769.1 - 4.4e-08 32.6 0.4 2.7e-07 30.1 0.3 1.9 1 1 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_18 PF12847.2 EIE77769.1 - 2.1e-05 25.0 0.0 3.1e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIE77769.1 - 2.6e-05 23.8 0.0 3.4e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIE77769.1 - 0.00017 21.8 0.0 0.00025 21.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIE77769.1 - 0.00018 21.5 0.0 0.00025 21.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 EIE77769.1 - 0.00043 19.3 0.0 0.00051 19.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_2 PF00891.13 EIE77769.1 - 0.0068 15.6 0.0 0.0092 15.1 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Rsm22 PF09243.5 EIE77769.1 - 0.01 14.8 0.0 0.013 14.5 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_11 PF08241.7 EIE77769.1 - 0.013 15.9 0.0 0.021 15.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.12 EIE77769.1 - 0.018 14.1 0.0 0.023 13.7 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase CMAS PF02353.15 EIE77769.1 - 0.029 13.4 0.0 0.047 12.7 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.1 EIE77769.1 - 0.035 13.7 0.0 0.04 13.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Mei4 PF13971.1 EIE77769.1 - 0.046 12.6 0.0 0.062 12.2 0.0 1.1 1 0 0 1 1 1 0 Meiosis-specific protein Mei4 MetW PF07021.7 EIE77769.1 - 0.062 12.6 0.0 0.078 12.3 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_12 PF08242.7 EIE77769.1 - 0.063 13.7 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Oxidored-like PF09791.4 EIE77770.1 - 2.4e-06 26.8 4.5 4.2e-06 26.1 3.1 1.3 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal FAD_binding_1 PF00667.15 EIE77771.1 - 2.2e-56 190.7 0.0 4e-56 189.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EIE77771.1 - 6.3e-32 110.5 0.2 1.5e-31 109.3 0.1 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 EIE77771.1 - 2.1e-22 79.7 0.1 1.4e-21 77.0 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Ribosomal_L39 PF00832.15 EIE77772.1 - 1.8e-19 68.8 12.5 2e-19 68.7 8.7 1.0 1 0 0 1 1 1 1 Ribosomal L39 protein PALP PF00291.20 EIE77773.1 - 5.2e-47 160.5 0.0 7.1e-47 160.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.23 EIE77773.1 - 2.1e-15 56.2 0.0 5.9e-07 29.1 0.0 2.6 2 0 0 2 2 2 2 CBS domain Helicase_C_4 PF13871.1 EIE77773.1 - 0.014 14.7 0.0 0.028 13.8 0.0 1.4 1 0 0 1 1 1 0 Helicase_C-like NmrA PF05368.8 EIE77773.1 - 0.11 11.7 0.0 0.26 10.4 0.0 1.7 2 0 0 2 2 2 0 NmrA-like family Dynactin_p22 PF07426.6 EIE77774.1 - 1.3e-14 53.8 7.2 1.6e-14 53.5 5.0 1.1 1 0 0 1 1 1 1 Dynactin subunit p22 DUF148 PF02520.12 EIE77774.1 - 0.0023 17.6 7.5 0.032 14.0 1.8 2.3 2 0 0 2 2 2 2 Domain of unknown function DUF148 DASH_Dad2 PF08654.5 EIE77774.1 - 0.24 11.3 4.2 0.44 10.5 0.6 2.5 2 1 0 2 2 2 0 DASH complex subunit Dad2 FliJ PF02050.11 EIE77774.1 - 0.8 9.7 10.5 3 7.9 0.5 2.9 2 1 1 3 3 3 0 Flagellar FliJ protein DUF848 PF05852.6 EIE77774.1 - 1.1 9.0 8.1 0.17 11.7 2.6 1.9 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DUF4200 PF13863.1 EIE77774.1 - 1.6 8.6 9.6 15 5.5 0.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) AAA_23 PF13476.1 EIE77774.1 - 5.8 7.1 12.1 13 6.0 8.4 1.6 1 1 0 1 1 1 0 AAA domain Aa_trans PF01490.13 EIE77775.1 - 1.7e-72 244.2 28.9 3.2e-59 200.4 12.2 2.0 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EIE77775.1 - 2.6e-07 29.8 12.1 1.3e-05 24.2 0.5 2.9 3 0 0 3 3 3 2 Tryptophan/tyrosine permease family DUF962 PF06127.6 EIE77775.1 - 2 8.3 7.2 3.7 7.4 0.8 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF962) Dynactin PF12455.3 EIE77776.1 - 1.9e-63 213.9 9.5 1.9e-63 213.9 6.6 4.0 4 2 0 4 4 4 1 Dynein associated protein RNase_H2-Ydr279 PF09468.5 EIE77778.1 - 2.3e-26 92.7 0.1 3e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) APS_kinase PF01583.15 EIE77778.1 - 0.068 12.8 0.6 2.2 7.8 0.0 2.2 2 0 0 2 2 2 0 Adenylylsulphate kinase Pro_isomerase PF00160.16 EIE77779.1 - 1.6e-27 96.6 0.0 1.7e-27 96.5 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DDE_3 PF13358.1 EIE77780.1 - 1.7e-21 76.5 0.0 3.3e-21 75.5 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 EIE77780.1 - 0.0053 16.8 0.1 0.011 15.9 0.1 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.1 EIE77780.1 - 0.0066 16.4 0.1 0.012 15.5 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.1 EIE77780.1 - 0.035 13.7 0.0 0.084 12.5 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain DDE_1 PF03184.14 EIE77780.1 - 0.041 13.0 0.1 0.17 10.9 0.1 2.0 1 1 0 1 1 1 0 DDE superfamily endonuclease Imm21 PF15569.1 EIE77780.1 - 0.049 13.3 0.0 6 6.7 0.0 2.6 2 0 0 2 2 2 0 Immunity protein 21 rve PF00665.21 EIE77780.1 - 0.1 12.7 0.0 0.25 11.4 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain FadA PF09403.5 EIE77780.1 - 0.13 12.3 1.1 0.22 11.5 0.7 1.3 1 0 0 1 1 1 0 Adhesion protein FadA Pkinase PF00069.20 EIE77782.1 - 5.7e-67 225.5 0.0 9.9e-67 224.8 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE77782.1 - 1.2e-29 103.1 0.1 1.1e-28 99.9 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE77782.1 - 6.7e-07 28.5 0.0 0.77 8.6 0.0 3.2 3 0 0 3 3 3 3 Kinase-like Kdo PF06293.9 EIE77782.1 - 0.012 14.7 0.0 0.021 13.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family BNR PF02012.15 EIE77783.1 - 0.0014 18.0 82.3 0.1 12.5 1.0 16.3 17 0 0 17 17 17 7 BNR/Asp-box repeat PSII_BNR PF14870.1 EIE77783.1 - 0.22 10.4 14.2 0.059 12.3 0.2 5.3 7 1 1 8 8 8 0 Photosynthesis system II assembly factor YCF48 DUF2345 PF10106.4 EIE77784.1 - 0.035 13.7 0.2 0.053 13.1 0.1 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2345) XPG_N PF00752.12 EIE77785.1 - 8.8e-34 115.8 0.0 2.2e-33 114.5 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 EIE77785.1 - 9e-23 80.1 0.2 4.1e-22 78.0 0.0 2.1 2 0 0 2 2 2 1 XPG I-region Abhydrolase_6 PF12697.2 EIE77785.1 - 3.5e-07 30.3 0.0 5.7e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIE77785.1 - 0.0049 16.4 0.0 0.0085 15.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF1664 PF07889.7 EIE77785.1 - 0.021 14.6 1.1 0.038 13.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Pkinase PF00069.20 EIE77786.1 - 3.7e-16 59.0 0.0 9.5e-16 57.7 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE77786.1 - 1.5e-13 50.3 0.0 2.5e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase NHase_beta PF02211.10 EIE77786.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Nitrile hydratase beta subunit NDUFB10 PF10249.4 EIE77787.1 - 3.7e-08 33.5 0.4 4.1e-08 33.4 0.2 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 PH_4 PF15404.1 EIE77787.1 - 0.078 12.5 0.1 0.099 12.1 0.1 1.2 1 0 0 1 1 1 0 Pleckstrin homology domain Sec63 PF02889.11 EIE77789.1 - 2.1e-51 175.0 0.2 3.2e-51 174.4 0.1 1.2 1 0 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.26 EIE77789.1 - 2.7e-21 75.0 0.7 2.7e-21 75.0 0.5 1.9 2 0 0 2 2 2 1 DnaJ domain Ribosomal_L17 PF01196.14 EIE77791.1 - 3.2e-36 123.7 1.0 1.2e-35 121.9 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L17 5_3_exonuc PF01367.15 EIE77791.1 - 0.073 13.3 0.9 0.15 12.3 0.4 1.6 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold TAP42 PF04177.7 EIE77792.1 - 1.8e-91 306.6 13.4 2e-91 306.4 9.3 1.0 1 0 0 1 1 1 1 TAP42-like family DUF3496 PF12001.3 EIE77792.1 - 0.13 12.5 3.7 0.3 11.3 2.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3496) DUF2937 PF11157.3 EIE77792.1 - 0.44 9.8 5.9 0.12 11.7 1.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) DUF1586 PF07625.6 EIE77792.1 - 0.55 10.0 2.5 6.3 6.6 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1586) Pribosyltran PF00156.22 EIE77793.1 - 1.2e-17 63.8 0.1 1.6e-17 63.4 0.1 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EIE77793.1 - 0.00079 18.6 0.0 0.0011 18.2 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.1 EIE77793.1 - 0.078 12.2 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase WD40 PF00400.27 EIE77794.1 - 1.9e-18 65.5 12.3 1.9e-08 33.8 0.1 5.4 6 0 0 6 6 6 3 WD domain, G-beta repeat HlyIII PF03006.15 EIE77796.1 - 3.6e-58 196.6 22.8 4.2e-58 196.3 15.8 1.0 1 0 0 1 1 1 1 Haemolysin-III related Mem_trans PF03547.13 EIE77796.1 - 0.25 9.5 3.5 2 6.6 2.4 2.4 1 1 0 1 1 1 0 Membrane transport protein DUF4231 PF14015.1 EIE77796.1 - 0.47 10.4 5.2 0.55 10.2 0.0 2.8 1 1 1 3 3 3 0 Protein of unknown function (DUF4231) EmrE PF13536.1 EIE77796.1 - 1.1 9.5 16.9 0.5 10.5 5.0 3.5 2 2 1 3 3 3 0 Multidrug resistance efflux transporter G-gamma PF00631.17 EIE77798.1 - 1.3e-19 69.7 0.1 1.4e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 GGL domain HAP1_N PF04849.8 EIE77798.1 - 0.023 13.6 0.7 0.027 13.4 0.5 1.0 1 0 0 1 1 1 0 HAP1 N-terminal conserved region Nup84_Nup100 PF04121.8 EIE77799.1 - 4e-24 84.3 9.2 4e-24 84.3 6.4 1.6 2 0 0 2 2 2 1 Nuclear pore protein 84 / 107 Dsl1_N PF11988.3 EIE77799.1 - 0.00022 20.2 1.5 0.026 13.3 0.1 2.4 2 0 0 2 2 2 2 Retrograde transport protein Dsl1 N terminal DUF1837 PF08878.6 EIE77800.1 - 0.052 13.1 0.0 0.1 12.1 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1837) DUF1980 PF09323.5 EIE77800.1 - 1 9.0 6.9 0.77 9.4 3.4 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF1980) B56 PF01603.15 EIE77801.1 - 3.1e-138 460.8 5.2 4.2e-138 460.3 3.6 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Ecm29 PF13001.2 EIE77802.1 - 6.2e-67 226.1 2.2 2.2e-36 125.4 0.1 3.2 2 1 1 3 3 3 2 Proteasome stabiliser HEAT_2 PF13646.1 EIE77802.1 - 1.1e-18 67.3 0.8 0.067 13.4 0.0 8.6 7 2 1 8 8 8 4 HEAT repeats HEAT PF02985.17 EIE77802.1 - 2.3e-17 61.4 9.1 0.019 14.9 0.0 12.6 14 0 0 14 14 14 2 HEAT repeat HEAT_EZ PF13513.1 EIE77802.1 - 4.2e-12 46.1 0.8 0.82 10.2 0.0 9.9 10 1 1 11 11 11 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EIE77802.1 - 9.7e-07 29.1 2.8 0.0018 18.6 0.0 6.4 5 4 3 8 8 8 1 Vacuolar 14 Fab1-binding region DNA_alkylation PF08713.6 EIE77802.1 - 0.0029 17.1 2.1 0.32 10.4 0.0 4.2 5 0 0 5 5 5 1 DNA alkylation repair enzyme Ipi1_N PF12333.3 EIE77802.1 - 0.012 15.6 0.4 1.1e+02 2.8 0.0 5.4 3 2 2 5 5 5 0 Rix1 complex component involved in 60S ribosome maturation Arm PF00514.18 EIE77802.1 - 0.012 15.3 0.0 0.27 11.1 0.1 3.1 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat UNC-93 PF05978.11 EIE77803.1 - 9.7e-12 44.6 2.2 9.7e-12 44.6 1.5 2.4 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.11 EIE77803.1 - 4.5e-11 42.0 26.3 6.5e-11 41.5 18.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily HEAT_EZ PF13513.1 EIE77804.1 - 5.1e-05 23.6 4.8 0.23 12.0 0.0 5.9 7 0 0 7 7 7 1 HEAT-like repeat HEAT_2 PF13646.1 EIE77804.1 - 0.00096 19.3 1.2 0.95 9.7 0.2 3.5 3 2 0 3 3 3 2 HEAT repeats SEN1_N PF12726.2 EIE77804.1 - 0.0063 14.6 0.8 0.014 13.5 0.2 1.7 2 0 0 2 2 2 1 SEN1 N terminal HEAT PF02985.17 EIE77804.1 - 0.0086 16.0 0.9 3.9 7.8 0.0 4.6 4 0 0 4 4 4 1 HEAT repeat DUF2013 PF09431.5 EIE77804.1 - 0.018 14.7 0.8 4.7 6.9 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2013) Imm28 PF15574.1 EIE77804.1 - 0.074 12.6 0.0 0.2 11.1 0.0 1.7 1 0 0 1 1 1 0 Immunity protein 28 SNF2_N PF00176.18 EIE77805.1 - 1.4e-64 217.7 0.0 2.3e-64 217.0 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.5 EIE77805.1 - 1.5e-12 47.6 3.1 2.7e-11 43.5 2.0 2.4 1 1 0 1 1 1 1 Rad54 N terminal Helicase_C PF00271.26 EIE77805.1 - 3.2e-12 46.1 0.0 6.3e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EIE77805.1 - 6.4e-08 31.7 0.0 5.8e-07 28.6 0.0 2.3 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.24 EIE77805.1 - 7.2e-06 25.6 0.0 0.00015 21.3 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 EIE77805.1 - 0.00077 19.3 0.0 0.0038 17.0 0.0 2.2 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit MtrH PF02007.13 EIE77805.1 - 0.12 11.3 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase MtrH subunit SpoIISB_antitox PF14185.1 EIE77806.1 - 0.046 13.4 0.3 0.11 12.2 0.2 1.7 1 0 0 1 1 1 0 Antitoxin SpoIISB, type II toxin-antitoxin system Mucin PF01456.12 EIE77807.1 - 9.2 6.0 14.6 9 6.0 10.1 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein UNC-50 PF05216.8 EIE77808.1 - 0.11 11.7 3.7 0.15 11.2 2.6 1.2 1 0 0 1 1 1 0 UNC-50 family ubiquitin PF00240.18 EIE77809.1 - 3.2e-17 61.6 0.3 5.6e-17 60.9 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EIE77809.1 - 2e-06 27.4 0.0 3.5e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EIE77809.1 - 0.00025 21.1 0.0 0.00032 20.8 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 EIE77809.1 - 0.0047 16.8 0.1 0.012 15.5 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like CLU_N PF15044.1 EIE77809.1 - 0.033 14.3 0.0 0.059 13.5 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial function, CLU-N-term Ubiquitin_2 PF14560.1 EIE77809.1 - 0.039 14.2 0.3 0.12 12.6 0.2 1.9 1 1 0 1 1 1 0 Ubiquitin-like domain GMP_synt_C PF00958.17 EIE77811.1 - 1.1e-36 124.4 0.1 2.5e-36 123.2 0.1 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.23 EIE77811.1 - 1.4e-35 122.4 0.0 3.1e-35 121.3 0.0 1.5 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EIE77811.1 - 1.7e-10 40.7 0.0 3.2e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase C26 NAD_synthase PF02540.12 EIE77811.1 - 1.7e-08 33.6 0.0 2.8e-06 26.4 0.0 2.2 2 0 0 2 2 2 2 NAD synthase QueC PF06508.8 EIE77811.1 - 0.0015 17.8 0.1 0.093 12.0 0.0 2.8 3 0 0 3 3 3 1 Queuosine biosynthesis protein QueC ThiI PF02568.9 EIE77811.1 - 0.0047 16.4 0.0 0.011 15.2 0.0 1.6 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) tRNA_Me_trans PF03054.11 EIE77811.1 - 0.0055 15.2 0.1 0.013 14.1 0.0 1.5 2 0 0 2 2 2 1 tRNA methyl transferase Asn_synthase PF00733.16 EIE77811.1 - 0.041 13.3 0.0 0.073 12.5 0.0 1.4 1 0 0 1 1 1 0 Asparagine synthase ATP_bind_3 PF01171.15 EIE77811.1 - 0.16 11.4 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 PP-loop family PAPS_reduct PF01507.14 EIE77811.1 - 0.16 11.7 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family DUF544 PF04424.8 EIE77814.1 - 3.7e-08 33.2 0.0 3.7e-08 33.2 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF544) tRNA_lig_CPD PF08302.6 EIE77814.1 - 0.07 12.3 5.5 1.4 8.0 0.0 2.1 2 0 0 2 2 2 0 Fungal tRNA ligase phosphodiesterase domain HSF_DNA-bind PF00447.12 EIE77815.1 - 2.4e-18 66.2 0.6 2.7e-18 66.0 0.4 1.0 1 0 0 1 1 1 1 HSF-type DNA-binding Pkinase PF00069.20 EIE77816.1 - 3.4e-45 154.2 0.0 9.5e-45 152.7 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE77816.1 - 2e-27 95.9 0.2 1.3e-26 93.2 0.1 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EIE77816.1 - 0.0015 17.5 0.0 0.0028 16.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 EIE77816.1 - 0.011 14.5 0.0 0.018 13.8 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 YrbL-PhoP_reg PF10707.4 EIE77816.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Pox_MCEL PF03291.11 EIE77819.1 - 7.1e-86 288.0 0.0 9.6e-86 287.6 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_18 PF12847.2 EIE77819.1 - 3.1e-08 34.1 0.0 4.9e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIE77819.1 - 2.6e-07 30.9 0.1 7.2e-07 29.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIE77819.1 - 4.5e-07 29.7 0.0 8.2e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIE77819.1 - 1.5e-06 28.5 0.0 3.2e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIE77819.1 - 1.8e-06 27.6 0.0 2.8e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIE77819.1 - 1.3e-05 25.6 0.0 3.7e-05 24.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 EIE77819.1 - 0.00022 20.3 0.0 0.00035 19.6 0.0 1.3 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family MTS PF05175.9 EIE77819.1 - 0.0006 19.2 0.0 0.00094 18.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.7 EIE77819.1 - 0.0056 16.0 0.1 0.015 14.6 0.0 1.7 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW CYSTM PF12734.2 EIE77819.1 - 0.029 14.4 3.6 0.029 14.4 2.5 4.6 3 2 1 4 4 3 0 Cysteine-rich TM module stress tolerance DUF2433 PF10360.4 EIE77820.1 - 2.6e-30 105.4 0.7 5.3e-30 104.4 0.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) RRM_6 PF14259.1 EIE77820.1 - 1.1e-10 41.3 0.0 3e-10 39.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EIE77820.1 - 2.7e-08 33.3 0.1 5.1e-08 32.4 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Metallophos_2 PF12850.2 EIE77820.1 - 0.00028 20.7 0.0 0.00063 19.6 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EIE77820.1 - 0.0013 18.1 0.0 0.0033 16.8 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase RRM_5 PF13893.1 EIE77820.1 - 0.01 15.6 0.0 0.03 14.1 0.0 1.7 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2407_C PF13373.1 EIE77821.1 - 8.2e-05 22.5 2.0 0.00046 20.1 0.1 2.0 1 1 1 2 2 2 2 DUF2407 C-terminal domain TMEM237 PF15383.1 EIE77822.1 - 0.12 11.4 0.0 0.14 11.2 0.0 1.0 1 0 0 1 1 1 0 Transmembrane protein 237 Pkinase PF00069.20 EIE77823.1 - 2.2e-33 115.5 0.6 3.9e-33 114.6 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE77823.1 - 3.6e-11 42.6 0.0 7.4e-11 41.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIE77823.1 - 2.2e-05 24.2 0.1 0.0031 17.2 0.0 2.9 3 0 0 3 3 3 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EIE77823.1 - 0.025 13.4 0.1 0.025 13.4 0.1 1.4 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Androgen_recep PF02166.11 EIE77823.1 - 0.22 10.3 3.9 0.29 9.9 2.7 1.1 1 0 0 1 1 1 0 Androgen receptor DAO PF01266.19 EIE77826.1 - 6.8e-55 186.4 0.0 1.4e-54 185.3 0.0 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIE77826.1 - 6e-07 29.3 0.2 1.2e-05 25.2 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EIE77826.1 - 6.3e-07 29.4 0.1 0.00018 21.4 0.1 3.0 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EIE77826.1 - 2e-06 26.9 0.2 2.2e-05 23.4 0.1 2.1 1 1 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 EIE77826.1 - 5.4e-06 26.2 0.0 0.053 13.2 0.0 2.7 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EIE77826.1 - 6.2e-06 26.4 0.0 8.1e-05 22.7 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EIE77826.1 - 3.3e-05 22.9 0.5 0.0021 16.9 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Mqo PF06039.10 EIE77826.1 - 0.00057 18.1 0.0 0.012 13.7 0.0 2.5 3 0 0 3 3 3 1 Malate:quinone oxidoreductase (Mqo) Thi4 PF01946.12 EIE77826.1 - 0.00069 18.7 0.5 0.0016 17.5 0.1 1.8 3 0 0 3 3 3 1 Thi4 family Trp_halogenase PF04820.9 EIE77826.1 - 0.00072 18.3 0.2 0.0077 14.9 0.1 2.0 2 0 0 2 2 2 1 Tryptophan halogenase ApbA PF02558.11 EIE77826.1 - 0.0033 16.8 0.0 0.0058 16.0 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.9 EIE77826.1 - 0.0042 15.6 0.2 0.5 8.7 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Saccharop_dh PF03435.13 EIE77826.1 - 0.0069 15.4 0.0 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase Pyr_redox PF00070.22 EIE77826.1 - 0.015 15.6 0.3 0.13 12.7 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.14 EIE77826.1 - 0.025 13.7 0.0 0.055 12.6 0.0 1.6 2 0 0 2 2 2 0 GMC oxidoreductase Lycopene_cycl PF05834.7 EIE77826.1 - 0.056 12.3 0.0 1.8 7.4 0.0 2.5 3 0 0 3 3 3 0 Lycopene cyclase protein Shikimate_DH PF01488.15 EIE77826.1 - 0.065 13.3 0.0 0.21 11.6 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Amino_oxidase PF01593.19 EIE77826.1 - 0.082 11.9 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase PAP2 PF01569.16 EIE77828.1 - 5.3e-12 45.5 6.3 5.3e-12 45.5 4.4 2.2 2 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 EIE77828.1 - 7.2e-06 25.6 3.1 1.3e-05 24.7 2.2 1.5 1 0 0 1 1 1 1 PAP2 superfamily Abhydrolase_3 PF07859.8 EIE77830.1 - 3.1e-22 79.2 0.1 4.7e-22 78.6 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EIE77830.1 - 2.9e-20 72.4 0.1 5.7e-20 71.5 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 EIE77830.1 - 0.00028 20.6 0.0 0.00049 19.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family UFD1 PF03152.9 EIE77833.1 - 8.5e-35 119.4 0.1 1.1e-34 119.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 Glyco_hydro_18 PF00704.23 EIE77834.1 - 0.00013 21.5 0.7 0.0063 16.0 0.1 2.5 1 1 1 2 2 2 2 Glycosyl hydrolases family 18 DUF2475 PF10629.4 EIE77834.1 - 0.18 12.1 2.2 0.82 9.9 0.0 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF2475) Astro_capsid PF03115.9 EIE77834.1 - 2 6.6 18.5 2.9 6.0 12.8 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor DUF1688 PF07958.6 EIE77835.1 - 6e-150 499.4 0.0 6.8e-150 499.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) Afi1 PF07792.7 EIE77839.1 - 2e-43 147.8 0.9 2e-42 144.6 0.0 2.8 3 1 0 3 3 3 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.5 EIE77839.1 - 1.3e-37 127.9 0.0 3.2e-37 126.6 0.0 1.7 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 EIE77839.1 - 7.4e-12 44.4 0.2 5.7e-06 25.0 0.0 3.7 2 1 1 3 3 3 2 Transport protein Avl9 DUF2347 PF09804.4 EIE77839.1 - 4.5e-11 42.5 0.0 5.8e-05 22.5 0.0 2.6 3 0 0 3 3 3 2 Uncharacterized conserved protein (DUF2347) Skp1 PF01466.14 EIE77840.1 - 1.9e-39 133.5 2.2 3.3e-39 132.7 1.5 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 EIE77840.1 - 1.7e-27 95.3 0.3 5.9e-27 93.5 0.1 1.9 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain BTB PF00651.26 EIE77840.1 - 0.021 14.8 0.0 0.21 11.5 0.0 2.1 1 1 0 1 1 1 0 BTB/POZ domain Mnd1 PF03962.10 EIE77841.1 - 1.2e-52 178.3 14.6 1.3e-51 174.9 10.2 1.9 1 1 0 1 1 1 1 Mnd1 family DUF4094 PF13334.1 EIE77841.1 - 0.0032 17.8 2.2 0.0067 16.7 1.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4094) WEMBL PF05701.6 EIE77841.1 - 0.027 12.9 14.3 0.036 12.5 9.9 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light GAS PF13851.1 EIE77841.1 - 0.029 13.5 14.3 0.051 12.7 9.9 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Vfa1 PF08432.5 EIE77841.1 - 0.05 13.6 10.3 0.074 13.0 7.2 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CaM_bdg_C0 PF10562.4 EIE77841.1 - 0.097 12.5 6.1 0.33 10.8 4.2 2.0 1 0 0 1 1 1 0 Calmodulin-binding domain C0 of NMDA receptor NR1 subunit Phage_GP20 PF06810.6 EIE77841.1 - 0.11 11.9 16.4 0.042 13.2 9.6 1.6 2 0 0 2 2 2 0 Phage minor structural protein GP20 IncA PF04156.9 EIE77841.1 - 0.31 10.6 10.9 0.18 11.3 6.4 1.5 2 0 0 2 2 2 0 IncA protein V_ATPase_I PF01496.14 EIE77841.1 - 0.32 8.7 6.9 0.4 8.4 4.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6 PF04111.7 EIE77841.1 - 0.44 9.5 13.3 0.6 9.0 9.2 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 FAM194 PF14977.1 EIE77841.1 - 0.55 9.1 2.8 3.7 6.4 0.8 2.7 1 1 1 2 2 2 0 FAM194 protein DUF745 PF05335.8 EIE77841.1 - 1 8.8 10.7 1.5 8.3 7.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF745) DUF342 PF03961.8 EIE77841.1 - 1.1 7.6 7.5 1.5 7.1 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) IncFII_repA PF02387.10 EIE77841.1 - 3.3 6.8 9.5 5.4 6.0 6.6 1.3 1 0 0 1 1 1 0 IncFII RepA protein family DUF4375 PF14300.1 EIE77841.1 - 3.3 7.7 7.4 3 7.8 3.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4375) DPM3 PF08285.6 EIE77841.1 - 3.5 7.5 6.1 2.2 8.1 0.5 2.4 1 1 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF4337 PF14235.1 EIE77841.1 - 7.4 6.3 11.3 13 5.6 7.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) FAD_binding_3 PF01494.14 EIE77842.1 - 6.9e-09 35.2 0.0 1.6e-08 34.0 0.0 1.7 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EIE77842.1 - 4.7e-06 26.5 0.1 1.2e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thioredoxin_8 PF13905.1 EIE77842.1 - 0.00043 20.3 0.0 0.0012 18.8 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like FAD_binding_2 PF00890.19 EIE77842.1 - 0.0018 17.1 0.0 0.0034 16.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EIE77842.1 - 0.002 17.0 0.0 0.0065 15.4 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EIE77842.1 - 0.0036 17.6 0.0 0.017 15.5 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIE77842.1 - 0.0055 15.2 0.0 0.011 14.2 0.0 1.5 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 EIE77842.1 - 0.017 14.2 0.0 0.025 13.6 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.9 EIE77842.1 - 0.035 13.9 0.0 0.065 13.0 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EIE77842.1 - 0.053 13.1 0.0 8.3 6.0 0.0 2.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 EIE77842.1 - 0.054 12.3 0.0 0.15 10.8 0.0 1.7 1 0 0 1 1 1 0 Glucose inhibited division protein A Methyltransf_11 PF08241.7 EIE77844.1 - 3.7e-08 33.7 0.0 8.2e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIE77844.1 - 0.00017 20.7 0.0 0.0004 19.5 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 EIE77844.1 - 0.00088 19.0 0.0 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIE77844.1 - 0.004 17.4 0.0 0.017 15.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_8 PF05148.10 EIE77844.1 - 0.014 15.0 0.0 0.019 14.6 0.0 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase CheR PF01739.13 EIE77844.1 - 0.11 11.7 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain PAP1 PF08601.5 EIE77845.1 - 3.7e-18 66.3 7.1 4.7e-18 65.9 4.9 1.3 1 1 0 1 1 1 1 Transcription factor PAP1 bZIP_1 PF00170.16 EIE77845.1 - 3.4e-07 30.1 21.3 6.8e-07 29.1 12.4 2.9 2 1 0 2 2 2 1 bZIP transcription factor DUF2580 PF10824.3 EIE77845.1 - 0.1 12.9 1.0 0.44 10.9 0.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2580) NYD-SP28_assoc PF14775.1 EIE77845.1 - 0.16 11.6 4.5 0.092 12.4 1.1 2.1 2 0 0 2 2 2 0 Sperm tail C-terminal domain DUF4407 PF14362.1 EIE77845.1 - 0.17 10.8 1.9 0.23 10.4 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ATP-cone PF03477.11 EIE77845.1 - 0.26 11.7 4.9 0.54 10.7 0.0 3.2 3 2 1 5 5 5 0 ATP cone domain bZIP_2 PF07716.10 EIE77845.1 - 0.29 10.9 18.4 24 4.8 12.8 2.6 1 1 0 1 1 1 0 Basic region leucine zipper SlyX PF04102.7 EIE77845.1 - 0.59 10.5 5.7 0.27 11.6 1.4 2.4 2 2 0 2 2 2 0 SlyX Phage_lysis PF03245.8 EIE77845.1 - 1.3 9.0 8.6 2.9 7.9 6.0 1.5 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein HWE_HK PF07536.9 EIE77845.1 - 1.9 8.9 4.7 1.8 9.0 1.3 2.3 2 1 0 2 2 2 0 HWE histidine kinase Prion PF00377.13 EIE77845.1 - 2.9 7.6 5.3 1.4 8.6 0.2 2.7 3 1 1 4 4 4 0 Prion/Doppel alpha-helical domain Pkinase PF00069.20 EIE77846.1 - 1.1e-71 241.0 0.0 1.4e-71 240.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE77846.1 - 1.9e-34 118.9 0.0 2.5e-34 118.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE77846.1 - 7.3e-07 28.4 0.0 1.5e-06 27.3 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 EIE77846.1 - 0.00012 21.2 0.0 0.00022 20.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EIE77846.1 - 0.002 17.4 0.5 0.0055 16.0 0.0 1.9 3 0 0 3 3 3 1 PhoP regulatory network protein YrbL APH PF01636.18 EIE77846.1 - 0.003 17.3 0.1 0.0084 15.8 0.2 1.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family EcoEI_R_C PF08463.5 EIE77847.1 - 0.027 14.3 0.5 0.04 13.7 0.1 1.5 2 0 0 2 2 2 0 EcoEI R protein C-terminal ATPgrasp_ST PF14397.1 EIE77847.1 - 0.11 11.6 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp DUF2315 PF10231.4 EIE77848.1 - 0.0042 16.9 1.6 0.0062 16.4 1.1 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2315) DPBB_1 PF03330.13 EIE77849.1 - 6.1e-13 48.5 0.0 8.9e-13 48.0 0.0 1.4 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EIE77849.1 - 0.00073 19.2 0.1 0.00099 18.7 0.0 1.2 1 0 0 1 1 1 1 Barwin family Ras PF00071.17 EIE77850.1 - 5.8e-28 97.3 0.1 7.2e-28 97.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIE77850.1 - 3.3e-19 69.5 0.0 4.4e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIE77850.1 - 8.1e-08 31.7 0.1 9.7e-08 31.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EIE77850.1 - 1.2e-05 24.6 0.1 1.4e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 EIE77850.1 - 0.0011 17.7 0.2 0.0066 15.1 0.0 1.8 1 1 1 2 2 2 1 G-protein alpha subunit MMR_HSR1 PF01926.18 EIE77850.1 - 0.023 14.6 0.0 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase SRPRB PF09439.5 EIE77850.1 - 0.058 12.6 0.0 0.066 12.4 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit CorA PF01544.13 EIE77851.1 - 1.5e-33 116.0 8.8 4.5e-31 107.9 5.0 3.1 1 1 1 2 2 2 1 CorA-like Mg2+ transporter protein SAM_decarbox PF01536.11 EIE77853.1 - 5.1e-100 334.3 0.0 2.6e-56 190.6 0.0 3.0 2 1 1 3 3 3 3 Adenosylmethionine decarboxylase Ins_allergen_rp PF06757.8 EIE77853.1 - 0.058 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Insect allergen related repeat, nitrile-specifier detoxification zf-RVT PF13966.1 EIE77855.1 - 1.9e-09 37.6 1.5 4.5e-09 36.5 1.0 1.6 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase RVT_1 PF00078.22 EIE77855.1 - 8.5e-06 25.2 0.0 1.6e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CTDII PF01556.13 EIE77856.1 - 8.7e-25 86.4 4.9 4.4e-22 77.7 0.0 2.5 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ PF00226.26 EIE77856.1 - 8.1e-20 70.3 0.8 1.9e-19 69.1 0.6 1.7 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EIE77856.1 - 1.5e-12 47.3 21.7 3e-12 46.3 15.1 1.5 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EIE77856.1 - 7.4e-05 22.4 5.5 0.013 15.1 0.6 2.3 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family DZR PF12773.2 EIE77856.1 - 0.63 9.8 7.2 4.2 7.2 0.5 2.5 2 0 0 2 2 2 0 Double zinc ribbon Elf1 PF05129.8 EIE77857.1 - 7.2e-18 64.0 9.0 4.7e-15 55.0 6.2 2.2 1 1 0 1 1 1 1 Transcription elongation factor Elf1 like Proteasome PF00227.21 EIE77858.1 - 3.4e-38 130.8 0.3 4.2e-38 130.5 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit DUF1024 PF06260.7 EIE77858.1 - 0.081 13.0 0.0 0.45 10.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1024) Proteasome PF00227.21 EIE77859.1 - 4e-52 176.2 0.2 4.8e-52 176.0 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit BcrAD_BadFG PF01869.15 EIE77859.1 - 0.082 12.1 0.1 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family Pex14_N PF04695.8 EIE77860.1 - 6.1e-16 58.7 5.5 3.8e-15 56.1 3.8 2.2 1 1 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2833 PF11090.3 EIE77860.1 - 0.1 12.7 0.4 2.8 8.1 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2833) DUF2400 PF09674.5 EIE77860.1 - 0.15 11.7 4.4 0.043 13.5 0.9 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2400) Cation_efflux PF01545.16 EIE77861.1 - 9.9e-66 221.7 12.0 1.3e-65 221.2 8.3 1.2 1 0 0 1 1 1 1 Cation efflux family Metallophos PF00149.23 EIE77861.1 - 3.6e-39 134.2 0.3 3.6e-39 134.2 0.2 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metal_resist PF13801.1 EIE77861.1 - 1.6 8.7 2.5 3.1 7.7 1.7 1.4 1 0 0 1 1 1 0 Heavy-metal resistance Cyclin_N PF00134.18 EIE77862.1 - 9.6e-06 25.1 0.4 1.4e-05 24.6 0.3 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 EIE77862.1 - 0.034 14.5 0.1 0.05 14.0 0.0 1.4 1 0 0 1 1 1 0 Cyclin Ribosomal_L35Ae PF01247.13 EIE77867.1 - 5.8e-42 141.3 1.7 6.5e-42 141.2 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 EIE77867.1 - 0.0029 17.5 0.1 0.33 10.8 0.0 2.1 2 0 0 2 2 2 2 RimM N-terminal domain Nuc_sug_transp PF04142.10 EIE77868.1 - 0.0016 17.6 1.3 0.0021 17.1 0.9 1.5 1 1 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.15 EIE77868.1 - 0.014 15.4 3.5 0.014 15.4 2.4 2.6 2 1 0 2 2 2 0 EamA-like transporter family FA_desaturase PF00487.19 EIE77868.1 - 0.074 12.4 6.0 0.015 14.7 1.7 1.7 1 1 1 2 2 2 0 Fatty acid desaturase DUF3147 PF11345.3 EIE77868.1 - 0.086 12.8 2.5 0.091 12.7 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3147) MerC PF03203.9 EIE77868.1 - 0.19 12.1 4.7 0.71 10.2 3.2 2.0 1 1 1 2 2 2 0 MerC mercury resistance protein Tmemb_14 PF03647.8 EIE77868.1 - 3.9 7.9 6.4 0.74 10.2 1.4 2.0 2 1 0 2 2 2 0 Transmembrane proteins 14C EmrE PF13536.1 EIE77868.1 - 9.5 6.4 12.0 0.092 12.9 0.7 2.6 2 1 0 2 2 2 0 Multidrug resistance efflux transporter SAS4 PF15460.1 EIE77869.1 - 1.3e-05 25.0 11.7 4.4e-05 23.2 7.0 2.2 1 1 1 2 2 2 1 Something about silencing, SAS, complex subunit 4 RestrictionSfiI PF11487.3 EIE77869.1 - 0.036 13.2 1.1 0.057 12.5 0.7 1.3 1 0 0 1 1 1 0 Type II restriction enzyme SfiI PEHE PF15275.1 EIE77869.1 - 0.85 10.0 13.0 15 6.0 6.3 2.7 2 1 0 2 2 2 0 PEHE domain Syntaxin_2 PF14523.1 EIE77869.1 - 0.86 9.6 9.7 0.046 13.7 2.3 2.0 2 1 1 3 3 3 0 Syntaxin-like protein COQ9 PF08511.6 EIE77871.1 - 3.8e-29 100.0 0.5 5.2e-29 99.5 0.4 1.2 1 0 0 1 1 1 1 COQ9 Ribosomal_L18e PF00828.14 EIE77872.1 - 2.3e-24 86.2 0.1 2.3e-24 86.2 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 TPR_11 PF13414.1 EIE77873.1 - 1.1e-42 143.4 18.9 4.8e-15 54.9 3.5 6.5 3 2 2 6 6 6 6 TPR repeat TPR_2 PF07719.12 EIE77873.1 - 8.6e-29 97.1 13.4 0.00026 20.6 0.0 9.6 10 0 0 10 10 9 6 Tetratricopeptide repeat TPR_1 PF00515.23 EIE77873.1 - 1.2e-28 97.4 22.8 3.7e-05 23.1 0.1 9.1 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_16 PF13432.1 EIE77873.1 - 2.7e-22 78.8 1.6 1.3e-06 28.9 0.0 5.5 3 2 3 6 6 6 5 Tetratricopeptide repeat TPR_17 PF13431.1 EIE77873.1 - 2.6e-19 67.7 13.3 0.00066 19.6 0.0 8.4 8 1 1 9 9 8 5 Tetratricopeptide repeat TPR_8 PF13181.1 EIE77873.1 - 7.3e-16 56.6 21.7 0.0011 18.5 0.0 9.1 9 1 1 10 10 10 4 Tetratricopeptide repeat TPR_14 PF13428.1 EIE77873.1 - 3.6e-14 51.9 3.2 0.035 14.7 0.0 7.6 5 2 3 8 8 8 4 Tetratricopeptide repeat TPR_12 PF13424.1 EIE77873.1 - 4.8e-13 48.8 18.7 3.3e-05 23.7 0.1 6.2 3 2 4 7 7 7 6 Tetratricopeptide repeat TPR_19 PF14559.1 EIE77873.1 - 2.1e-10 40.8 10.9 0.0032 17.7 0.0 6.1 4 1 4 8 8 8 5 Tetratricopeptide repeat TPR_9 PF13371.1 EIE77873.1 - 2e-08 33.9 0.3 0.00061 19.5 0.0 4.0 3 2 0 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.1 EIE77873.1 - 2.7e-05 23.3 1.8 0.28 10.1 0.0 4.3 2 2 2 4 4 4 1 Tetratricopeptide repeat NARP1 PF12569.3 EIE77873.1 - 0.00026 19.9 10.1 0.00066 18.5 0.1 3.7 2 2 2 4 4 4 2 NMDA receptor-regulated protein 1 TPR_6 PF13174.1 EIE77873.1 - 0.0014 18.9 12.5 5.3 7.7 0.0 7.4 9 0 0 9 9 7 1 Tetratricopeptide repeat TPR_7 PF13176.1 EIE77873.1 - 0.0094 15.6 7.9 29 4.7 0.1 6.6 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_20 PF14561.1 EIE77873.1 - 0.015 15.3 2.4 0.94 9.6 0.0 4.0 3 1 2 5 5 4 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 EIE77873.1 - 0.036 13.2 0.3 0.37 10.0 0.0 2.7 3 0 0 3 3 3 0 SHNi-TPR DUF3983 PF13137.1 EIE77873.1 - 0.054 13.1 0.0 0.19 11.4 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3983) MIT PF04212.13 EIE77873.1 - 0.07 13.0 5.5 33 4.4 0.0 4.2 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain zf-met PF12874.2 EIE77874.1 - 0.02 15.0 0.1 0.036 14.2 0.1 1.4 1 0 0 1 1 1 0 Zinc-finger of C2H2 type Nop14 PF04147.7 EIE77874.1 - 0.11 10.4 34.7 0.14 10.1 24.0 1.2 1 0 0 1 1 1 0 Nop14-like family TIP_N PF12457.3 EIE77874.1 - 0.45 10.6 24.3 2.2 8.3 16.8 2.0 1 1 0 1 1 1 0 Tuftelin interacting protein N terminal SprA-related PF12118.3 EIE77874.1 - 1.8 7.8 18.0 2.2 7.5 12.5 1.1 1 0 0 1 1 1 0 SprA-related family Drc1-Sld2 PF11719.3 EIE77874.1 - 2.2 7.2 23.4 2.4 7.1 16.2 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein Raftlin PF15250.1 EIE77874.1 - 2.6 6.4 11.3 2.9 6.3 7.8 1.1 1 0 0 1 1 1 0 Raftlin CENP-T PF15511.1 EIE77874.1 - 7.2 5.7 20.2 8.3 5.5 14.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DUF913 PF06025.7 EIE77874.1 - 7.8 5.1 7.8 9.1 4.9 5.4 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) NPR3 PF03666.8 EIE77874.1 - 9.4 4.6 12.5 9.9 4.5 8.6 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 MAS20 PF02064.10 EIE77875.1 - 2.3e-27 95.3 1.8 1.5e-26 92.7 1.2 2.3 1 1 0 1 1 1 1 MAS20 protein import receptor zf-MYND PF01753.13 EIE77875.1 - 0.00013 21.7 9.6 0.00022 21.0 6.6 1.4 1 0 0 1 1 1 1 MYND finger Tox-WTIP PF15654.1 EIE77875.1 - 0.15 11.6 0.3 0.4 10.3 0.2 1.7 1 0 0 1 1 1 0 Toxin with a conserved tryptophan and TIP tripeptide motif OmpH PF03938.9 EIE77875.1 - 0.17 11.8 6.3 0.45 10.4 4.3 1.7 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF2256 PF10013.4 EIE77875.1 - 0.99 9.2 4.7 4.5 7.1 3.3 2.1 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2256) Fungal_trans PF04082.13 EIE77877.1 - 7.9e-05 21.6 0.0 9.5e-05 21.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Kelch_4 PF13418.1 EIE77878.1 - 2.2e-17 62.5 2.0 0.0003 20.4 0.0 5.5 5 1 0 5 5 5 4 Galactose oxidase, central domain Kelch_1 PF01344.20 EIE77878.1 - 1.4e-14 53.2 11.8 7.3e-05 22.2 0.3 5.2 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.1 EIE77878.1 - 5e-14 51.9 3.8 8.8e-05 22.5 0.0 5.2 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.1 EIE77878.1 - 6.8e-14 51.4 4.6 9.4e-05 22.2 0.3 5.2 5 0 0 5 5 5 3 Kelch motif Kelch_6 PF13964.1 EIE77878.1 - 3.2e-13 49.2 8.3 0.003 17.6 0.1 4.8 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.10 EIE77878.1 - 6.1e-09 35.3 13.6 0.059 13.1 0.2 6.0 6 1 0 6 6 6 4 Kelch motif RAG2 PF03089.9 EIE77878.1 - 3.4e-05 22.7 0.5 0.022 13.5 0.1 3.6 2 1 2 4 4 4 2 Recombination activating protein 2 Tetraspannin PF00335.15 EIE77879.1 - 1.9e-20 73.0 15.0 3e-20 72.4 10.4 1.2 1 0 0 1 1 1 1 Tetraspanin family DUF4386 PF14329.1 EIE77879.1 - 0.059 12.8 12.2 0.28 10.6 8.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4386) COPI_assoc PF08507.5 EIE77879.1 - 5 6.8 15.7 0.64 9.7 3.2 2.8 3 0 0 3 3 3 0 COPI associated protein Ribosomal_L18p PF00861.17 EIE77880.1 - 4.1e-32 110.8 0.5 6e-32 110.3 0.0 1.5 2 0 0 2 2 2 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 EIE77880.1 - 1.2e-30 105.9 2.8 1.7e-30 105.4 2.0 1.2 1 0 0 1 1 1 1 Ribosomal L18 C-terminal region DUF3306 PF11748.3 EIE77881.1 - 0.6 10.7 9.2 1.1 9.9 6.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) PMSI1 PF15322.1 EIE77881.1 - 1.1 8.3 5.5 1.3 8.0 3.8 1.2 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative Nop25 PF09805.4 EIE77881.1 - 1.5 8.8 20.4 2.6 8.1 14.1 1.6 1 1 0 1 1 1 0 Nucleolar protein 12 (25kDa) LON PF02190.11 EIE77882.1 - 2.4e-10 40.4 0.0 5.1e-10 39.3 0.0 1.5 1 1 0 1 1 1 1 ATP-dependent protease La (LON) domain O-FucT PF10250.4 EIE77883.1 - 1e-15 57.7 3.5 2.4e-10 40.0 2.6 2.9 2 1 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase RLAN PF14401.1 EIE77883.1 - 0.0078 15.7 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATPgrasp N-terminal domain DUF3021 PF11457.3 EIE77883.1 - 0.17 11.8 0.5 0.57 10.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3021) Acetyltransf_1 PF00583.19 EIE77884.1 - 3.4e-07 30.2 0.1 1.3e-06 28.2 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EIE77884.1 - 0.00025 21.1 0.1 0.00048 20.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.13 EIE77885.1 - 2e-88 294.5 0.4 3.7e-88 293.7 0.3 1.4 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 EIE77885.1 - 6.3e-20 70.6 0.2 1.9e-19 69.0 0.1 1.9 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain HTH_11 PF08279.7 EIE77885.1 - 0.14 11.8 0.8 0.3 10.7 0.5 1.5 1 0 0 1 1 1 0 HTH domain Mito_carr PF00153.22 EIE77886.1 - 4.2e-62 205.8 2.6 6.5e-22 77.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PrcB_C PF14343.1 EIE77886.1 - 0.059 13.0 0.5 1.9 8.2 0.1 2.9 3 0 0 3 3 3 0 PrcB C-terminal PAS_3 PF08447.6 EIE77889.1 - 2.9e-11 43.2 0.0 8.8e-11 41.7 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.5 EIE77889.1 - 1.5e-05 24.9 0.0 3.4e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS PF00989.19 EIE77889.1 - 5.7e-05 22.8 0.0 0.00015 21.5 0.0 1.7 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.1 EIE77889.1 - 0.0005 20.4 0.0 0.001 19.3 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS_11 PF14598.1 EIE77889.1 - 0.003 17.4 0.0 0.0063 16.4 0.0 1.5 1 0 0 1 1 1 1 PAS domain Pex14_N PF04695.8 EIE77890.1 - 0.00065 19.7 2.3 0.0095 15.9 1.6 2.1 1 1 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region COX7a PF02238.10 EIE77890.1 - 0.0069 16.0 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIa WRKY PF03106.10 EIE77890.1 - 0.056 13.2 2.2 0.13 12.0 1.5 1.6 1 0 0 1 1 1 0 WRKY DNA -binding domain MCPVI PF02993.9 EIE77890.1 - 0.15 12.1 1.1 0.16 12.1 0.2 1.4 2 0 0 2 2 2 0 Minor capsid protein VI zf-TRAF PF02176.13 EIE77891.1 - 1.2e-10 41.6 45.7 9.5e-07 29.1 7.7 4.3 2 1 3 5 5 4 3 TRAF-type zinc finger zf-C3HC4_2 PF13923.1 EIE77891.1 - 1.4e-07 31.3 15.8 1.4e-07 31.3 11.0 4.3 2 1 3 5 5 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIE77891.1 - 9.5e-07 28.5 16.1 9.5e-07 28.5 11.1 3.7 2 1 0 2 2 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EIE77891.1 - 4.5e-06 26.2 12.2 4.5e-06 26.2 8.5 4.0 2 1 1 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIE77891.1 - 1e-05 25.0 17.8 1e-05 25.0 12.3 4.0 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EIE77891.1 - 0.00087 19.3 11.8 0.00087 19.3 8.2 3.7 2 2 0 2 2 1 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 EIE77891.1 - 0.0013 18.5 15.5 0.0013 18.5 10.7 3.7 4 0 0 4 4 3 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EIE77891.1 - 0.0017 18.0 15.3 0.0017 18.0 10.6 3.9 3 1 0 3 3 2 1 zinc-RING finger domain U-box PF04564.10 EIE77891.1 - 0.014 15.3 3.5 0.018 15.0 0.1 2.7 3 0 0 3 3 3 0 U-box domain Sina PF03145.11 EIE77891.1 - 0.022 14.4 1.2 0.022 14.4 0.8 4.2 1 1 2 4 4 4 0 Seven in absentia protein family HALZ PF02183.13 EIE77891.1 - 0.032 13.9 10.5 2.2 8.0 1.1 3.7 2 1 1 3 3 3 0 Homeobox associated leucine zipper ADIP PF11559.3 EIE77891.1 - 0.27 11.1 14.3 5.1 6.9 1.3 3.4 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding bZIP_1 PF00170.16 EIE77891.1 - 0.47 10.4 9.3 2.7 7.9 0.5 3.6 2 1 1 3 3 3 0 bZIP transcription factor DASH_Dad3 PF08656.5 EIE77891.1 - 0.75 9.5 5.4 0.13 11.9 0.3 2.2 2 0 0 2 2 2 0 DASH complex subunit Dad3 DUF904 PF06005.7 EIE77891.1 - 0.98 9.7 13.1 0.86 9.9 3.5 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF904) TRM PF02005.11 EIE77892.1 - 2.8e-119 398.4 0.1 3.2e-119 398.2 0.0 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.11 EIE77892.1 - 0.0036 16.9 0.0 0.0067 16.0 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.10 EIE77892.1 - 0.0062 15.9 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 MTS PF05175.9 EIE77892.1 - 0.0096 15.3 0.1 0.025 13.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EIE77892.1 - 0.036 14.0 0.0 0.07 13.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF1492 PF07374.6 EIE77892.1 - 0.16 12.0 3.1 2.9 8.0 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1492) PX PF00787.19 EIE77893.1 - 1.1e-26 92.8 0.1 1.2e-26 92.6 0.0 1.1 1 0 0 1 1 1 1 PX domain SAP PF02037.22 EIE77894.1 - 4.7e-13 48.3 0.5 4.7e-13 48.3 0.4 3.3 4 0 0 4 4 4 2 SAP domain HeH PF12949.2 EIE77894.1 - 0.035 13.6 0.7 0.25 10.8 0.3 2.5 2 0 0 2 2 2 0 HeH/LEM domain CNH PF00780.17 EIE77896.1 - 2.4e-59 201.0 0.0 4.5e-59 200.1 0.0 1.3 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.15 EIE77896.1 - 2.9e-35 121.7 0.3 6.2e-35 120.6 0.2 1.6 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.1 EIE77896.1 - 3.2e-23 82.1 0.0 6.8e-23 81.0 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EIE77896.1 - 0.051 13.7 0.1 0.29 11.3 0.0 2.4 2 0 0 2 2 2 0 PH domain CUE PF02845.11 EIE77898.1 - 3.6e-11 42.3 0.0 7.3e-11 41.3 0.0 1.5 1 0 0 1 1 1 1 CUE domain RecX PF02631.11 EIE77898.1 - 0.14 12.3 1.9 3.7 7.7 0.1 2.4 2 0 0 2 2 2 0 RecX family PAP_central PF04928.12 EIE77899.1 - 7.9e-46 155.9 0.7 1.3e-45 155.1 0.5 1.3 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 EIE77899.1 - 1.5e-09 37.6 0.1 2.9e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 EIE77899.1 - 3.8e-05 23.9 0.4 8.9e-05 22.7 0.0 1.8 2 0 0 2 2 2 1 Nucleotidyltransferase domain DUF1722 PF08349.6 EIE77899.1 - 0.014 15.2 0.3 16 5.3 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1722) Mad3_BUB1_I PF08311.7 EIE77899.1 - 0.028 14.2 0.6 0.31 10.8 0.0 2.3 2 0 0 2 2 2 0 Mad3/BUB1 homology region 1 Snf7 PF03357.16 EIE77900.1 - 5.8e-41 139.7 10.2 5.8e-41 139.7 7.1 1.8 2 0 0 2 2 2 1 Snf7 DASH_Dad4 PF08650.5 EIE77900.1 - 0.014 15.2 0.7 0.029 14.2 0.5 1.5 1 0 0 1 1 1 0 DASH complex subunit Dad4 Upf2 PF04050.9 EIE77900.1 - 0.15 11.7 3.3 0.19 11.5 2.3 1.2 1 0 0 1 1 1 0 Up-frameshift suppressor 2 G-gamma PF00631.17 EIE77902.1 - 4.3e-15 55.2 0.0 5.2e-15 54.9 0.0 1.1 1 0 0 1 1 1 1 GGL domain Nt_Gln_amidase PF09764.4 EIE77903.1 - 8.9e-26 90.3 0.7 9.3e-26 90.2 0.5 1.0 1 0 0 1 1 1 1 N-terminal glutamine amidase Brix PF04427.13 EIE77904.1 - 1.3e-51 174.9 0.2 1.7e-51 174.6 0.1 1.1 1 0 0 1 1 1 1 Brix domain Bromodomain PF00439.20 EIE77904.1 - 0.05 13.5 0.0 0.083 12.8 0.0 1.5 1 0 0 1 1 1 0 Bromodomain adh_short_C2 PF13561.1 EIE77905.1 - 0.00045 20.0 0.0 0.00045 20.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EIE77905.1 - 0.0021 18.0 0.0 0.0023 17.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase TPR_11 PF13414.1 EIE77906.1 - 1.7e-22 78.7 9.7 1.2e-10 40.8 1.7 3.5 2 1 1 3 3 3 3 TPR repeat TPR_1 PF00515.23 EIE77906.1 - 8.5e-20 69.4 6.3 5.3e-05 22.6 0.3 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 EIE77906.1 - 7.3e-16 56.7 10.0 0.00074 19.2 0.1 5.8 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 EIE77906.1 - 9.6e-13 48.4 10.1 2.7e-05 24.7 0.1 3.8 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 EIE77906.1 - 1.1e-12 47.3 13.0 0.006 17.1 0.1 5.5 3 2 2 5 5 4 4 Tetratricopeptide repeat TPR_19 PF14559.1 EIE77906.1 - 7.1e-12 45.4 6.3 9.5e-07 29.0 0.3 3.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 EIE77906.1 - 6.3e-11 41.5 7.5 0.00031 20.6 0.2 4.6 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_20 PF14561.1 EIE77906.1 - 3.9e-09 36.5 3.2 0.0019 18.2 0.1 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EIE77906.1 - 1e-07 31.7 8.5 2.6e-05 24.0 0.6 3.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EIE77906.1 - 6.8e-07 28.6 5.3 0.37 10.7 0.1 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 EIE77906.1 - 1.3e-05 24.6 1.3 1.1 9.2 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 EIE77906.1 - 4.2e-05 23.6 5.0 0.00011 22.1 0.3 2.7 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EIE77906.1 - 0.00027 20.7 7.8 0.043 13.6 0.1 3.4 2 1 1 3 3 3 3 Tetratricopeptide repeat ChAPs PF09295.5 EIE77906.1 - 0.0077 15.0 0.8 0.25 10.0 0.2 2.3 1 1 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) DUF1641 PF07849.6 EIE77906.1 - 0.014 15.0 0.1 0.048 13.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1641) TPR_4 PF07721.9 EIE77906.1 - 0.03 14.7 1.3 0.064 13.7 0.0 2.4 2 0 0 2 2 1 0 Tetratricopeptide repeat TPR_6 PF13174.1 EIE77906.1 - 0.066 13.7 5.9 23 5.7 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat zf-C2H2 PF00096.21 EIE77908.1 - 7.5e-06 25.9 1.0 0.0032 17.7 0.0 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-Di19 PF05605.7 EIE77908.1 - 0.0003 20.8 1.4 0.74 9.9 0.0 2.5 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 EIE77908.1 - 0.0041 17.1 0.2 0.022 14.8 0.2 2.3 1 1 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 EIE77908.1 - 0.011 16.0 4.5 0.03 14.6 0.0 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger PID_2 PF14719.1 EIE77908.1 - 0.12 12.0 0.1 0.22 11.1 0.1 1.4 1 0 0 1 1 1 0 Phosphotyrosine interaction domain (PTB/PID) zf-C2HC_2 PF13913.1 EIE77908.1 - 1 9.0 0.0 1 9.0 0.0 2.8 4 0 0 4 4 4 0 zinc-finger of a C2HC-type TPR_11 PF13414.1 EIE77910.1 - 2.1e-23 81.7 9.6 5.8e-11 41.8 1.7 3.3 2 1 1 3 3 3 3 TPR repeat TPR_1 PF00515.23 EIE77910.1 - 4e-21 73.6 6.3 2.7e-05 23.5 0.3 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 EIE77910.1 - 3.6e-17 60.8 10.0 0.00038 20.1 0.1 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 EIE77910.1 - 4.7e-14 51.6 12.7 0.003 18.0 0.1 5.5 2 2 4 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 EIE77910.1 - 3.2e-13 49.9 11.6 1.3e-05 25.7 0.1 3.9 2 2 1 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 EIE77910.1 - 5.2e-12 45.9 8.7 4.5e-07 30.1 0.3 3.7 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 EIE77910.1 - 2.8e-11 42.6 9.9 0.00016 21.6 0.2 4.8 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_20 PF14561.1 EIE77910.1 - 1.7e-09 37.6 4.4 0.00093 19.2 0.1 3.5 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 EIE77910.1 - 2.8e-08 33.5 9.4 1.3e-05 25.0 0.6 3.7 2 2 1 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EIE77910.1 - 6.2e-08 31.8 5.8 0.19 11.6 0.1 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 EIE77910.1 - 1.1e-06 28.0 1.3 0.56 10.1 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 EIE77910.1 - 1.2e-05 25.2 5.0 5.1e-05 23.3 0.3 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EIE77910.1 - 5.3e-05 22.9 8.3 0.02 14.7 0.1 3.4 2 1 1 3 3 3 3 Tetratricopeptide repeat ChAPs PF09295.5 EIE77910.1 - 0.0018 17.0 0.8 0.098 11.3 0.3 2.2 1 1 1 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_6 PF13174.1 EIE77910.1 - 0.0053 17.1 5.9 12 6.6 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF1641 PF07849.6 EIE77910.1 - 0.014 14.9 0.1 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) TPR_4 PF07721.9 EIE77910.1 - 0.033 14.6 0.0 0.033 14.6 0.0 2.7 3 0 0 3 3 1 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EIE77910.1 - 0.13 12.2 0.5 3.4 7.6 0.0 2.5 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat BTAD PF03704.12 EIE77910.1 - 0.34 11.1 7.4 2.2 8.5 1.2 2.9 2 1 0 2 2 2 0 Bacterial transcriptional activator domain HTH_28 PF13518.1 EIE77912.1 - 5.8e-05 23.0 0.0 0.00012 22.0 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.1 EIE77912.1 - 0.0049 16.4 0.7 0.018 14.6 0.0 2.0 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.1 EIE77912.1 - 0.012 15.7 0.0 0.023 14.8 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn helix CLP_protease PF00574.18 EIE77914.1 - 4.9e-70 234.8 0.1 6.1e-70 234.5 0.1 1.0 1 0 0 1 1 1 1 Clp protease Iso_dh PF00180.15 EIE77915.1 - 1.1e-82 277.7 0.0 1.4e-82 277.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Fungal_trans PF04082.13 EIE77916.1 - 1.9e-08 33.4 1.3 1.9e-08 33.4 0.9 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF3325 PF11804.3 EIE77916.1 - 0.011 15.6 0.1 0.024 14.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3325) DUF221 PF02714.10 EIE77917.1 - 1.8e-20 73.0 16.9 2e-19 69.6 9.7 2.8 2 1 0 2 2 2 2 Domain of unknown function DUF221 RSN1_TM PF13967.1 EIE77918.1 - 1.6e-28 99.2 3.4 2.1e-28 98.8 2.3 1.2 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport Zn_clus PF00172.13 EIE77919.1 - 3.8e-06 26.7 8.4 7e-06 25.8 5.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.19 EIE77919.1 - 0.08 12.7 0.3 3.3 7.5 0.0 2.5 2 0 0 2 2 2 0 PAS fold BCS1_N PF08740.6 EIE77920.1 - 1.2e-54 184.7 0.5 1.9e-54 184.1 0.3 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EIE77920.1 - 3.7e-20 72.4 0.0 6.8e-20 71.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EIE77920.1 - 6.8e-06 26.8 0.0 2.8e-05 24.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EIE77920.1 - 4e-05 23.9 0.0 9.7e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.1 EIE77920.1 - 0.00055 19.9 0.2 0.0013 18.7 0.1 1.7 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 EIE77920.1 - 0.00068 18.6 0.0 0.0013 17.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 EIE77920.1 - 0.00081 19.2 0.0 0.0018 18.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EIE77920.1 - 0.002 18.2 0.0 0.012 15.7 0.0 2.3 3 0 0 3 3 2 1 AAA domain AAA_25 PF13481.1 EIE77920.1 - 0.0022 17.4 0.0 0.0046 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EIE77920.1 - 0.004 17.1 0.0 0.0098 15.8 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.17 EIE77920.1 - 0.0042 17.2 0.0 0.012 15.7 0.0 2.0 2 0 0 2 2 1 1 RNA helicase ABC_tran PF00005.22 EIE77920.1 - 0.0062 16.8 0.0 0.012 15.8 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_5 PF07728.9 EIE77920.1 - 0.0073 16.0 0.0 0.028 14.1 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 EIE77920.1 - 0.0096 15.4 0.0 0.019 14.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain RuvB_N PF05496.7 EIE77920.1 - 0.025 13.6 0.0 0.042 12.8 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Zeta_toxin PF06414.7 EIE77920.1 - 0.035 13.2 0.0 0.063 12.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin MMR_HSR1 PF01926.18 EIE77920.1 - 0.052 13.5 0.0 0.14 12.1 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase Arch_ATPase PF01637.13 EIE77920.1 - 0.06 13.0 0.0 0.2 11.2 0.0 2.0 2 0 0 2 2 2 0 Archaeal ATPase AAA_14 PF13173.1 EIE77920.1 - 0.063 13.1 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 EIE77920.1 - 0.069 13.6 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein AAA_24 PF13479.1 EIE77920.1 - 0.11 12.1 0.0 0.4 10.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EIE77920.1 - 0.13 12.0 0.0 0.32 10.7 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain TFIIB PF00382.14 EIE77922.1 - 2.2e-43 145.9 3.2 1.7e-24 85.4 0.4 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 EIE77922.1 - 2.3e-15 55.6 0.5 3.8e-15 54.9 0.3 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_C PF02984.14 EIE77922.1 - 0.00017 21.4 0.1 0.029 14.3 0.0 2.3 2 0 0 2 2 2 2 Cyclin, C-terminal domain Cyclin_N PF00134.18 EIE77922.1 - 0.14 11.6 2.0 0.63 9.6 0.3 2.1 1 1 1 2 2 2 0 Cyclin, N-terminal domain AhpC-TSA PF00578.16 EIE77923.1 - 2.7e-33 114.2 0.0 3.6e-33 113.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EIE77923.1 - 7e-12 45.1 0.0 1.1e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 EIE77923.1 - 2.4e-10 39.9 0.0 4.2e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Sugar_tr PF00083.19 EIE77924.1 - 8.6e-87 291.5 31.8 4.4e-78 262.8 8.5 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EIE77924.1 - 2.2e-19 69.3 39.4 3.8e-13 48.8 7.4 3.3 2 1 1 3 3 3 3 Major Facilitator Superfamily DUF1077 PF06417.7 EIE77924.1 - 0.099 11.9 2.1 0.13 11.6 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1077) Cation_efflux PF01545.16 EIE77925.1 - 2.7e-28 98.8 12.9 1.6e-27 96.3 9.0 1.9 1 1 0 1 1 1 1 Cation efflux family DUF3902 PF13042.1 EIE77925.1 - 1.1 8.5 8.7 0.053 12.8 2.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3902) PH_9 PF15410.1 EIE77926.1 - 1.4e-09 38.1 0.0 2.4e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EIE77926.1 - 4.6e-07 30.0 0.0 7e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 PH domain Zn_clus PF00172.13 EIE77927.1 - 0.0055 16.5 14.2 0.01 15.7 9.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 EIE77928.1 - 3.2e-70 236.2 0.3 5.3e-70 235.5 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE77928.1 - 1.1e-35 122.9 0.0 1.8e-35 122.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE77928.1 - 2.3e-05 23.5 0.0 6.3e-05 22.0 0.0 1.8 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.9 EIE77928.1 - 0.063 12.3 0.0 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIE77928.1 - 0.1 12.3 0.0 0.23 11.1 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family zf-RING_2 PF13639.1 EIE77930.1 - 9.9e-10 38.1 3.9 2.8e-09 36.6 2.7 1.8 1 1 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EIE77930.1 - 2.1e-07 30.9 0.9 3.4e-07 30.2 0.6 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EIE77930.1 - 3.6e-06 26.5 1.6 9.2e-06 25.2 1.1 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIE77930.1 - 7e-06 25.6 4.0 1.9e-05 24.3 2.9 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EIE77930.1 - 2.2e-05 24.4 1.5 2.2e-05 24.4 1.0 2.0 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EIE77930.1 - 2.6e-05 23.9 1.0 4e-05 23.3 0.7 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.3 EIE77930.1 - 0.0028 17.1 1.6 0.0043 16.5 1.1 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_3 PF13920.1 EIE77930.1 - 0.0032 17.1 3.1 0.0085 15.7 2.2 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EIE77930.1 - 0.0072 16.0 1.9 0.0094 15.6 0.6 1.6 1 1 0 1 1 1 1 RING-type zinc-finger FANCL_C PF11793.3 EIE77930.1 - 0.037 13.9 5.8 1.3 9.0 4.0 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.2 EIE77930.1 - 0.08 12.9 1.1 0.08 12.9 0.8 1.6 2 0 0 2 2 1 0 RING-variant domain zf-Di19 PF05605.7 EIE77930.1 - 0.083 13.0 1.5 0.98 9.5 0.1 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding C1_1 PF00130.17 EIE77930.1 - 0.3 10.8 4.5 0.66 9.7 0.7 2.4 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 EIE77930.1 - 1.4 8.6 4.5 16 5.2 0.1 2.9 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 Ribosomal_S8e PF01201.17 EIE77931.1 - 8e-51 171.6 0.7 9.5e-51 171.3 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e Ribosomal_L5_C PF00673.16 EIE77932.1 - 1.7e-23 82.1 0.0 2.4e-23 81.6 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 EIE77932.1 - 1.8e-19 69.2 0.1 5.7e-19 67.6 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L5 HGTP_anticodon2 PF12745.2 EIE77933.1 - 0.044 12.9 6.1 0.055 12.5 4.2 1.1 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs Macoilin PF09726.4 EIE77933.1 - 3.9 5.6 7.9 4.2 5.5 5.5 1.0 1 0 0 1 1 1 0 Transmembrane protein SR-25 PF10500.4 EIE77933.1 - 5.2 6.4 13.8 7.1 6.0 9.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ubiquitin PF00240.18 EIE77934.1 - 5.5e-07 28.8 1.0 3.1e-06 26.4 0.0 2.5 2 2 1 3 3 3 1 Ubiquitin family Ubiquitin_2 PF14560.1 EIE77934.1 - 0.00079 19.6 0.2 0.004 17.3 0.0 2.1 2 1 0 2 2 2 1 Ubiquitin-like domain CENP-I PF07778.6 EIE77934.1 - 0.23 9.6 1.6 0.32 9.1 1.1 1.2 1 0 0 1 1 1 0 Mis6 Polysacc_deac_1 PF01522.16 EIE77935.1 - 9.6e-26 89.8 0.0 1.7e-25 89.0 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase RAP1 PF07218.6 EIE77935.1 - 1.6 6.7 9.9 2.4 6.1 6.9 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Polysacc_deac_1 PF01522.16 EIE77936.1 - 8.9e-26 89.9 0.1 1.8e-25 88.9 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Cloacin_immun PF03513.9 EIE77936.1 - 0.068 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Cloacin immunity protein Macoilin PF09726.4 EIE77936.1 - 7.9 4.6 9.3 11 4.1 6.4 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF3518 PF12031.3 EIE77938.1 - 0.00067 18.5 0.1 0.00067 18.5 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3518) DDE_3 PF13358.1 EIE77939.1 - 2.8e-06 27.1 0.0 8.5e-06 25.5 0.0 1.8 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 EIE77939.1 - 8.3e-06 25.9 0.0 1.6e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.1 EIE77939.1 - 0.0091 15.9 0.4 0.022 14.7 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain DUF1804 PF08822.6 EIE77939.1 - 0.01 15.5 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1804) MIF4G PF02854.14 EIE77941.1 - 9.5e-49 165.6 3.5 1.9e-48 164.6 2.4 1.5 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 EIE77941.1 - 2.6e-06 27.2 1.7 4.9e-06 26.3 0.1 2.3 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 4G1 Borrelia_P83 PF05262.6 EIE77941.1 - 1.6 6.9 33.4 3.4 5.8 23.1 1.5 1 0 0 1 1 1 0 Borrelia P83/100 protein CDT1 PF08839.6 EIE77942.1 - 3.4e-06 27.0 0.0 5.4e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 DNA replication factor CDT1 like L27 PF02828.11 EIE77942.1 - 0.029 14.0 0.0 0.08 12.6 0.0 1.8 1 0 0 1 1 1 0 L27 domain Actin PF00022.14 EIE77943.1 - 3.7e-120 400.9 0.0 4.4e-120 400.7 0.0 1.0 1 0 0 1 1 1 1 Actin cobW PF02492.14 EIE77944.1 - 5.6e-18 65.0 0.1 1.1e-17 64.0 0.1 1.5 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 EIE77944.1 - 3.8e-10 39.3 0.0 6.4e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain Peptidase_M13 PF01431.16 EIE77944.1 - 0.0031 16.7 0.1 0.0044 16.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Glu-tRNAGln PF02686.10 EIE77944.1 - 1.8 8.3 6.3 15 5.5 0.1 3.5 3 1 1 4 4 4 0 Glu-tRNAGln amidotransferase C subunit AAA PF00004.24 EIE77945.1 - 9.9e-45 151.9 0.3 3.9e-44 150.0 0.0 2.1 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EIE77945.1 - 1.8e-09 37.4 0.1 5.3e-09 35.9 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EIE77945.1 - 5.5e-08 32.9 0.0 1.3e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EIE77945.1 - 3.9e-07 30.2 0.0 1.6e-06 28.2 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EIE77945.1 - 4.1e-06 26.9 0.8 0.00074 19.6 0.5 2.8 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 EIE77945.1 - 8.4e-06 24.8 0.0 1.6e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_19 PF13245.1 EIE77945.1 - 0.00014 21.5 0.1 0.00038 20.1 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 EIE77945.1 - 0.00016 21.6 0.0 0.00092 19.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EIE77945.1 - 0.00021 21.3 0.0 0.0004 20.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain UPF0079 PF02367.12 EIE77945.1 - 0.00029 20.4 0.1 0.015 14.8 0.0 2.4 1 1 1 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 RuvB_N PF05496.7 EIE77945.1 - 0.00047 19.2 0.0 0.0012 17.9 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 EIE77945.1 - 0.00055 19.3 0.7 0.012 15.0 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 EIE77945.1 - 0.001 19.8 0.0 0.0054 17.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EIE77945.1 - 0.0016 18.5 0.0 0.0035 17.4 0.0 1.6 1 0 0 1 1 1 1 RNA helicase NTPase_1 PF03266.10 EIE77945.1 - 0.002 17.8 0.0 0.007 16.0 0.0 1.9 1 0 0 1 1 1 1 NTPase AAA_11 PF13086.1 EIE77945.1 - 0.0028 17.2 1.1 0.0084 15.7 0.0 2.1 2 1 1 3 3 3 1 AAA domain NACHT PF05729.7 EIE77945.1 - 0.0031 17.1 0.1 0.053 13.1 0.0 2.3 2 0 0 2 2 2 1 NACHT domain IstB_IS21 PF01695.12 EIE77945.1 - 0.0041 16.5 0.0 0.0097 15.3 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 EIE77945.1 - 0.0043 15.8 0.0 0.0077 14.9 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 EIE77945.1 - 0.0055 16.5 0.0 0.017 15.0 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_3 PF07726.6 EIE77945.1 - 0.0061 16.1 0.0 0.017 14.7 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EIE77945.1 - 0.0062 16.8 0.1 0.057 13.7 0.0 2.4 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EIE77945.1 - 0.007 15.5 0.0 0.016 14.4 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.1 EIE77945.1 - 0.0075 15.8 0.0 0.017 14.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EIE77945.1 - 0.0088 15.7 0.7 0.17 11.5 0.0 2.8 2 1 1 3 3 3 1 Archaeal ATPase AAA_24 PF13479.1 EIE77945.1 - 0.014 15.0 0.1 0.033 13.7 0.1 1.6 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EIE77945.1 - 0.018 14.1 1.5 0.45 9.5 0.0 2.8 3 0 0 3 3 3 0 KaiC Zeta_toxin PF06414.7 EIE77945.1 - 0.023 13.8 0.0 0.042 12.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Sigma54_activat PF00158.21 EIE77945.1 - 0.045 13.2 0.1 1.2 8.5 0.0 2.7 3 0 0 3 3 2 0 Sigma-54 interaction domain Bac_DnaA PF00308.13 EIE77945.1 - 0.045 13.3 0.0 0.093 12.3 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein ABC_tran PF00005.22 EIE77945.1 - 0.094 13.0 0.1 0.38 11.0 0.0 2.2 2 1 0 2 2 1 0 ABC transporter Parvo_NS1 PF01057.12 EIE77945.1 - 0.12 11.2 0.0 0.22 10.3 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_23 PF13476.1 EIE77945.1 - 0.13 12.5 6.4 0.72 10.1 0.0 2.5 2 1 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.1 EIE77945.1 - 0.16 11.9 0.4 0.67 9.9 0.0 2.3 2 1 0 2 2 1 0 Sigma-54 interaction domain Glycos_transf_1 PF00534.15 EIE77946.1 - 6.1e-20 71.3 0.0 2e-19 69.6 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EIE77946.1 - 8e-08 32.4 0.0 1.6e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EIE77946.1 - 3.1e-05 24.1 0.0 0.00015 21.8 0.0 2.3 3 0 0 3 3 3 1 Glycosyl transferases group 1 CotH PF08757.6 EIE77947.1 - 3.1e-46 158.1 2.1 4.5e-46 157.5 1.5 1.2 1 0 0 1 1 1 1 CotH protein LON PF02190.11 EIE77948.1 - 3.2e-27 95.5 0.7 1.5e-20 73.7 0.0 2.2 1 1 0 2 2 2 2 ATP-dependent protease La (LON) domain zf-C3HC4_3 PF13920.1 EIE77948.1 - 0.00058 19.4 20.8 0.039 13.6 0.9 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIE77948.1 - 0.0025 17.7 25.0 0.011 15.7 2.2 2.7 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EIE77948.1 - 0.0063 16.3 22.7 0.27 11.1 8.4 2.8 2 0 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 EIE77948.1 - 0.0078 16.0 2.1 0.0078 16.0 1.4 2.9 2 0 0 2 2 2 1 Ring finger domain DUF4543 PF15076.1 EIE77948.1 - 0.025 14.5 0.0 0.079 13.0 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4543) zf-RING_5 PF14634.1 EIE77948.1 - 0.084 12.6 23.3 0.12 12.0 1.0 2.6 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_UBOX PF13445.1 EIE77948.1 - 7.8 6.3 13.4 0.22 11.2 0.4 2.9 2 0 0 2 2 2 0 RING-type zinc-finger CotH PF08757.6 EIE77950.1 - 1e-41 143.2 1.4 1.4e-41 142.7 1.0 1.2 1 0 0 1 1 1 1 CotH protein tRNA_U5-meth_tr PF05958.6 EIE77951.1 - 1.2e-14 53.7 0.3 2.6e-13 49.4 0.2 2.1 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.1 EIE77951.1 - 3.2e-11 43.0 1.2 6.6e-11 42.0 0.5 1.9 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EIE77951.1 - 3.5e-08 33.0 0.1 5.2e-08 32.4 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 EIE77951.1 - 2.1e-07 31.5 0.0 3.7e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 EIE77951.1 - 2.4e-07 30.4 0.3 7.4e-07 28.8 0.1 1.6 1 1 1 2 2 2 1 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 EIE77951.1 - 2e-06 27.8 0.0 3.9e-06 26.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EIE77951.1 - 4.6e-06 25.9 0.8 7.2e-06 25.3 0.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.10 EIE77951.1 - 5.1e-06 26.0 0.1 9e-06 25.1 0.1 1.4 1 1 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_4 PF02390.12 EIE77951.1 - 0.00034 19.7 0.5 0.00064 18.8 0.1 1.6 2 0 0 2 2 2 1 Putative methyltransferase UPF0020 PF01170.13 EIE77951.1 - 0.00078 19.0 0.2 0.0013 18.3 0.2 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 PCMT PF01135.14 EIE77951.1 - 0.0011 18.6 0.0 0.0018 17.8 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Met_10 PF02475.11 EIE77951.1 - 0.0018 17.9 0.3 0.0035 16.9 0.2 1.7 1 1 0 1 1 1 1 Met-10+ like-protein Ubie_methyltran PF01209.13 EIE77951.1 - 0.0058 15.7 0.1 0.0095 15.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EIE77951.1 - 0.0068 16.7 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EIE77951.1 - 0.0071 16.0 0.3 0.012 15.2 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIE77951.1 - 0.058 13.8 0.0 0.14 12.6 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain DREV PF05219.7 EIE77951.1 - 0.069 12.0 0.1 0.27 10.0 0.0 1.8 1 1 1 2 2 2 0 DREV methyltransferase Methyltransf_12 PF08242.7 EIE77951.1 - 0.072 13.5 0.0 0.22 12.0 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain N6_N4_Mtase PF01555.13 EIE77951.1 - 0.074 12.5 0.1 0.51 9.7 0.0 2.2 3 0 0 3 3 3 0 DNA methylase TPMT PF05724.6 EIE77951.1 - 0.13 11.6 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) KxDL PF10241.4 EIE77953.1 - 7.2e-18 64.2 4.6 8.3e-18 64.0 3.2 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein DUF4559 PF15112.1 EIE77953.1 - 0.022 13.9 2.5 0.023 13.8 1.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) Cor1 PF04803.7 EIE77953.1 - 0.031 14.0 6.7 0.051 13.3 4.1 1.6 1 1 1 2 2 2 0 Cor1/Xlr/Xmr conserved region BLOC1_2 PF10046.4 EIE77953.1 - 0.038 14.1 2.7 0.051 13.7 1.9 1.4 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF922 PF06037.6 EIE77953.1 - 0.048 12.9 1.4 0.07 12.4 0.3 1.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF922) DUF148 PF02520.12 EIE77953.1 - 0.059 13.1 4.0 0.13 12.0 2.4 1.9 1 1 1 2 2 2 0 Domain of unknown function DUF148 ApoLp-III PF07464.6 EIE77953.1 - 0.059 13.3 2.7 0.093 12.7 1.8 1.3 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DUF1043 PF06295.7 EIE77953.1 - 0.062 12.9 4.6 0.075 12.6 3.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) DUF3391 PF11871.3 EIE77953.1 - 0.066 13.4 0.7 0.093 12.9 0.5 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) GSCFA PF08885.6 EIE77953.1 - 0.076 12.5 0.1 0.1 12.1 0.1 1.2 1 0 0 1 1 1 0 GSCFA family Pox_RNA_pol PF03293.9 EIE77953.1 - 0.076 12.5 0.0 0.095 12.2 0.0 1.1 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase, 18 kD subunit Allexi_40kDa PF05549.6 EIE77953.1 - 0.079 12.2 0.6 0.089 12.0 0.4 1.0 1 0 0 1 1 1 0 Allexivirus 40kDa protein Streptin-Immun PF11083.3 EIE77953.1 - 0.096 12.6 3.9 4.3 7.3 0.6 3.2 1 1 3 4 4 4 0 Lantibiotic streptin immunity protein DUF2130 PF09903.4 EIE77953.1 - 0.099 11.3 4.7 0.11 11.2 3.3 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2130) Pollen_allerg_2 PF01620.11 EIE77953.1 - 0.11 12.8 0.2 0.11 12.7 0.1 1.2 1 0 0 1 1 1 0 Ribonuclease (pollen allergen) HSCB_C PF07743.8 EIE77953.1 - 0.13 12.7 1.7 0.25 11.8 0.7 1.9 1 1 0 1 1 1 0 HSCB C-terminal oligomerisation domain Snapin_Pallidin PF14712.1 EIE77953.1 - 0.14 12.5 3.4 0.23 11.8 2.3 1.5 1 1 0 1 1 1 0 Snapin/Pallidin DUF4269 PF14091.1 EIE77953.1 - 0.15 11.9 1.0 0.22 11.4 0.7 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4269) TMPIT PF07851.8 EIE77953.1 - 0.16 10.9 2.2 0.19 10.7 1.5 1.1 1 0 0 1 1 1 0 TMPIT-like protein CagY_M PF07337.6 EIE77953.1 - 0.25 10.8 1.7 0.71 9.3 1.2 1.7 1 1 0 1 1 1 0 DC-EC Repeat USP8_dimer PF08969.6 EIE77953.1 - 0.28 11.1 5.2 0.22 11.4 2.0 1.8 1 1 1 2 2 2 0 USP8 dimerisation domain V-SNARE PF05008.10 EIE77953.1 - 0.29 11.3 5.1 0.36 11.0 1.2 2.5 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus CotJB PF12652.2 EIE77953.1 - 0.33 11.0 5.5 4.7 7.3 3.4 2.2 1 1 1 2 2 2 0 CotJB protein Seryl_tRNA_N PF02403.17 EIE77953.1 - 0.45 10.5 4.2 0.71 9.9 2.9 1.3 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Syntaxin PF00804.20 EIE77953.1 - 0.65 10.1 4.5 1.2 9.3 3.1 1.4 1 1 0 1 1 1 0 Syntaxin Ada3 PF10198.4 EIE77953.1 - 1.1 8.9 5.3 3.3 7.4 3.7 1.7 1 1 0 1 1 1 0 Histone acetyltransferases subunit 3 Wbp11 PF09429.5 EIE77953.1 - 1.8 8.5 5.4 27 4.8 1.8 2.3 1 1 1 2 2 2 0 WW domain binding protein 11 DUF342 PF03961.8 EIE77953.1 - 2.1 6.6 4.3 2.4 6.4 3.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) AAA_23 PF13476.1 EIE77953.1 - 2.5 8.4 6.7 3.1 8.0 4.7 1.1 1 0 0 1 1 1 0 AAA domain RhoGAP PF00620.22 EIE77954.1 - 6.2e-39 133.0 0.4 1e-38 132.3 0.3 1.3 1 0 0 1 1 1 1 RhoGAP domain SE PF08491.5 EIE77954.1 - 0.039 12.7 0.1 0.068 11.9 0.0 1.4 1 0 0 1 1 1 0 Squalene epoxidase Ribosomal_S19e PF01090.14 EIE77955.1 - 3.1e-61 204.8 0.2 3.5e-61 204.7 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e ANAPC15 PF15243.1 EIE77956.1 - 9.2 6.4 9.4 0.4 10.7 1.0 2.4 2 2 1 3 3 3 0 Anaphase-promoting complex subunit 15 SR-25 PF10500.4 EIE77957.1 - 1.4 8.3 5.2 1.7 8.0 3.6 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein UBX PF00789.15 EIE77958.1 - 0.041 13.9 0.3 0.087 12.8 0.0 1.6 2 0 0 2 2 2 0 UBX domain DUF4610 PF15384.1 EIE77958.1 - 0.11 12.0 1.0 0.12 11.9 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4610) DUF3759 PF12585.3 EIE77959.1 - 1.1e-26 92.5 9.9 1.4e-26 92.2 6.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) Citrate_synt PF00285.16 EIE77959.1 - 0.014 14.1 0.8 0.015 14.0 0.6 1.2 1 0 0 1 1 1 0 Citrate synthase DUF2309 PF10070.4 EIE77959.1 - 0.037 12.1 1.8 0.04 12.0 1.3 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2309) AIPR PF10592.4 EIE77959.1 - 0.082 12.2 1.0 0.1 11.9 0.7 1.0 1 0 0 1 1 1 0 AIPR protein PepSY_2 PF13670.1 EIE77959.1 - 2.1 8.3 5.2 0.42 10.5 0.5 2.0 2 1 1 3 3 3 0 Peptidase propeptide and YPEB domain Glyco_transf_49 PF13896.1 EIE77960.1 - 3.1e-14 52.7 0.1 4.5e-14 52.2 0.1 1.3 1 0 0 1 1 1 1 Glycosyl-transferase for dystroglycan RGP PF03214.8 EIE77960.1 - 0.017 13.8 0.0 0.03 13.0 0.0 1.3 1 0 0 1 1 1 0 Reversibly glycosylated polypeptide CYSTM PF12734.2 EIE77961.1 - 1.2e-06 28.4 49.3 0.0017 18.3 28.7 3.7 1 1 1 2 2 2 1 Cysteine-rich TM module stress tolerance Extensin_2 PF04554.8 EIE77961.1 - 0.57 10.0 26.0 0.73 9.7 18.0 1.2 1 0 0 1 1 1 0 Extensin-like region DDE_3 PF13358.1 EIE77963.1 - 3.6e-16 59.2 0.1 2.4e-14 53.3 0.0 2.2 1 1 1 2 2 2 2 DDE superfamily endonuclease rve PF00665.21 EIE77963.1 - 0.004 17.2 0.0 0.006 16.6 0.0 1.3 1 1 0 1 1 1 1 Integrase core domain Phage_integrase PF00589.17 EIE77965.1 - 2.8e-07 30.3 0.2 3.7e-07 29.9 0.1 1.2 1 0 0 1 1 1 1 Phage integrase family RVT_1 PF00078.22 EIE77966.1 - 0.0018 17.6 0.0 0.0026 17.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) NSs PF11073.3 EIE77967.1 - 0.028 13.6 0.0 0.035 13.3 0.0 1.1 1 0 0 1 1 1 0 Rift valley fever virus non structural protein (NSs) like PSD3 PF07626.6 EIE77967.1 - 0.12 12.4 0.2 0.51 10.3 0.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1587) PAS_8 PF13188.1 EIE77968.1 - 0.083 12.7 0.0 0.097 12.5 0.0 1.1 1 0 0 1 1 1 0 PAS domain MAS20 PF02064.10 EIE77969.1 - 4.6e-22 78.2 0.7 2.5e-21 75.8 0.5 2.3 1 1 0 1 1 1 1 MAS20 protein import receptor SET PF00856.23 EIE77969.1 - 0.00033 21.0 2.4 0.019 15.2 0.0 2.9 3 1 0 3 3 3 1 SET domain zf-MYND PF01753.13 EIE77969.1 - 0.00073 19.3 6.8 0.0012 18.6 4.7 1.3 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 EIE77969.1 - 0.048 13.5 10.3 0.024 14.4 5.0 2.1 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Fibritin_C PF07921.7 EIE77969.1 - 0.067 13.1 0.7 4.5 7.2 0.0 2.7 2 0 0 2 2 2 0 Fibritin C-terminal region zf-C3HC4_2 PF13923.1 EIE77969.1 - 6 6.9 8.3 11 6.1 5.7 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_L2_C PF03947.13 EIE77970.1 - 3.4e-42 143.3 2.3 3.4e-42 143.3 1.6 1.5 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EIE77970.1 - 1.8e-15 56.6 0.1 4.4e-15 55.4 0.1 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Mito_carr PF00153.22 EIE77971.1 - 2.1e-26 91.4 0.1 1.1e-16 60.3 0.0 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein MFS_1 PF07690.11 EIE77972.1 - 1.8e-39 135.4 25.5 6.3e-32 110.6 7.6 2.7 1 1 2 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.19 EIE77972.1 - 4.9e-13 48.4 17.9 3.1e-10 39.2 2.9 2.6 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.1 EIE77972.1 - 6.6e-06 24.7 14.2 0.00095 17.6 0.6 2.8 2 1 1 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.2 EIE77972.1 - 7.8e-06 25.5 4.0 0.03 14.0 0.0 3.1 4 0 0 4 4 4 2 MFS_1 like family K-cyclin_vir_C PF09080.5 EIE77972.1 - 0.11 12.7 0.1 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 K cyclin, C terminal OATP PF03137.15 EIE77972.1 - 0.11 10.4 5.8 0.34 8.9 0.1 2.4 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DUF2235 PF09994.4 EIE77974.1 - 7.8e-27 94.3 0.0 8.2e-27 94.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) FSH1 PF03959.8 EIE77974.1 - 0.0093 15.4 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DDE_3 PF13358.1 EIE77975.1 - 4.5e-12 45.9 0.5 6.1e-12 45.5 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease NDUF_B6 PF09782.4 EIE77975.1 - 0.067 13.0 0.9 0.15 11.9 0.6 1.7 1 1 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit RVT_1 PF00078.22 EIE77977.1 - 1.8e-11 43.8 0.3 2.9e-11 43.1 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.12 EIE77978.1 - 7e-05 22.8 0.1 0.00024 21.0 0.1 1.9 1 0 0 1 1 1 1 Retrotransposon gag protein UBN2_2 PF14227.1 EIE77978.1 - 0.066 12.7 0.2 0.15 11.6 0.1 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Retrotrans_gag PF03732.12 EIE77983.1 - 7.2e-13 48.4 0.1 1.8e-12 47.1 0.1 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein gag-asp_proteas PF13975.1 EIE77983.1 - 0.00051 19.8 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EIE77983.1 - 0.00082 19.8 0.0 0.0024 18.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.18 EIE77983.1 - 0.00082 19.1 2.0 0.0021 17.9 1.4 1.7 1 0 0 1 1 1 1 Zinc knuckle RVP PF00077.15 EIE77983.1 - 0.0027 17.5 0.0 0.006 16.4 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.6 EIE77983.1 - 0.093 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC_4 PF14392.1 EIE77983.1 - 0.13 11.9 0.7 0.28 10.8 0.5 1.6 1 0 0 1 1 1 0 Zinc knuckle ING PF12998.2 EIE77984.1 - 0.056 13.7 0.7 0.083 13.1 0.5 1.3 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding Allexi_40kDa PF05549.6 EIE77984.1 - 0.064 12.5 0.8 0.08 12.2 0.5 1.0 1 0 0 1 1 1 0 Allexivirus 40kDa protein DDE_3 PF13358.1 EIE77985.1 - 3.6e-21 75.4 0.0 7.3e-21 74.4 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE77985.1 - 1.1e-15 57.4 1.9 2.8e-15 56.1 0.3 2.3 3 0 0 3 3 2 1 Transposase HTH_29 PF13551.1 EIE77985.1 - 2.6e-06 27.5 0.2 8.6e-06 25.8 0.2 1.9 2 0 0 2 2 1 1 Winged helix-turn helix HTH_38 PF13936.1 EIE77985.1 - 1.2e-05 24.7 0.1 3.3e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_32 PF13565.1 EIE77985.1 - 3.7e-05 24.4 2.3 0.02 15.6 0.1 3.7 4 0 0 4 4 4 1 Homeodomain-like domain HTH_23 PF13384.1 EIE77985.1 - 8e-05 22.1 0.1 0.0028 17.2 0.0 2.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.1 EIE77985.1 - 0.0013 18.6 0.0 0.0056 16.6 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.7 EIE77985.1 - 0.0014 18.0 0.7 0.024 14.0 0.0 2.8 4 0 0 4 4 4 1 Sigma-70, region 4 HTH_21 PF13276.1 EIE77985.1 - 0.0014 18.5 0.1 0.13 12.2 0.0 2.8 3 0 0 3 3 3 1 HTH-like domain HTH_7 PF02796.10 EIE77985.1 - 0.0022 17.7 1.1 0.1 12.4 0.0 2.8 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase rve PF00665.21 EIE77985.1 - 0.0064 16.5 0.0 0.02 14.9 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain LacI PF00356.16 EIE77985.1 - 0.018 14.6 1.7 2.8 7.6 0.2 2.7 3 0 0 3 3 3 0 Bacterial regulatory proteins, lacI family HTH_Tnp_4 PF13613.1 EIE77985.1 - 0.023 14.2 0.1 0.057 12.9 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_Tnp_ISL3 PF13542.1 EIE77985.1 - 0.037 13.1 0.2 8.4 5.6 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 CPSase_L_D3 PF02787.14 EIE77985.1 - 0.057 13.1 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain HTH_36 PF13730.1 EIE77985.1 - 0.083 13.0 0.4 4.1 7.6 0.0 2.9 3 0 0 3 3 2 0 Helix-turn-helix domain HTH_17 PF12728.2 EIE77985.1 - 0.2 11.8 2.4 15 5.9 0.1 3.2 3 0 0 3 3 3 0 Helix-turn-helix domain GP41 PF00517.12 EIE77986.1 - 0.87 9.1 4.5 0.48 9.9 0.2 2.4 2 1 0 2 2 2 0 Retroviral envelope protein rve PF00665.21 EIE77987.1 - 1.8e-39 134.5 0.0 2.2e-19 69.7 0.0 3.5 3 0 0 3 3 3 2 Integrase core domain RVT_1 PF00078.22 EIE77987.1 - 8.1e-29 100.5 2.9 2.5e-16 59.7 0.1 2.8 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 EIE77987.1 - 9.7e-16 58.0 1.1 7e-07 29.6 0.0 3.3 3 0 0 3 3 3 2 Aspartyl protease RVP PF00077.15 EIE77987.1 - 1.8e-13 50.2 1.4 1.5e-05 24.8 0.1 3.3 3 0 0 3 3 3 2 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EIE77987.1 - 2.6e-10 39.9 0.0 0.00049 19.8 0.0 2.6 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Chromo PF00385.19 EIE77987.1 - 1.5e-08 34.1 1.7 2.3e-08 33.6 0.3 2.0 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease PF09668.5 EIE77987.1 - 6.4e-06 25.7 0.4 0.16 11.5 0.1 3.3 3 0 0 3 3 3 2 Aspartyl protease rve_3 PF13683.1 EIE77987.1 - 6.9e-05 22.2 0.0 0.11 12.0 0.0 3.3 3 0 0 3 3 3 2 Integrase core domain Retrotrans_gag PF03732.12 EIE77987.1 - 0.00079 19.4 0.1 0.0091 16.0 0.0 3.0 2 0 0 2 2 2 1 Retrotransposon gag protein RVP_2 PF08284.6 EIE77987.1 - 0.0022 17.9 0.5 0.63 9.9 0.0 2.7 2 0 0 2 2 2 1 Retroviral aspartyl protease IncA PF04156.9 EIE77987.1 - 3.1 7.3 6.6 7 6.1 4.6 1.5 1 0 0 1 1 1 0 IncA protein Tox-REase-2 PF15646.1 EIE77988.1 - 0.14 12.0 0.1 0.16 11.8 0.1 1.2 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 2 RVT_1 PF00078.22 EIE77989.1 - 4.8e-26 91.4 0.0 8.9e-26 90.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EIE77990.1 - 8.7e-23 80.7 0.0 3.9e-22 78.6 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.1 EIE77990.1 - 0.0093 15.4 0.0 0.024 14.1 0.0 1.8 1 1 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.1 EIE77990.1 - 0.082 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 DDE domain RVT_1 PF00078.22 EIE77991.1 - 1.7e-22 79.8 0.9 1.7e-22 79.8 0.6 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EIE77991.1 - 1.2e-19 70.5 0.0 2.9e-19 69.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.12 EIE77991.1 - 5.3e-18 64.8 1.5 2.1e-17 62.9 0.4 2.6 2 0 0 2 2 2 1 Retrotransposon gag protein Asp_protease_2 PF13650.1 EIE77991.1 - 3.7e-06 27.3 0.0 7.6e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EIE77991.1 - 2.3e-05 24.1 0.0 4.4e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 EIE77991.1 - 0.00021 21.1 0.0 0.00061 19.6 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.6 EIE77991.1 - 0.00038 20.4 0.0 0.00084 19.2 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 EIE77991.1 - 0.038 13.5 0.0 0.099 12.2 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC PF00098.18 EIE77991.1 - 0.072 13.0 0.7 0.17 11.8 0.5 1.7 1 0 0 1 1 1 0 Zinc knuckle Asp_protease PF09668.5 EIE77993.1 - 6.6e-11 41.8 0.1 1.5e-10 40.6 0.0 1.6 2 0 0 2 2 2 1 Aspartyl protease Asp_protease_2 PF13650.1 EIE77993.1 - 7.9e-09 35.9 0.0 1.7e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 EIE77993.1 - 5.1e-07 29.5 0.0 1.6e-06 27.9 0.0 1.9 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.6 EIE77993.1 - 1.8e-06 27.8 0.0 3.4e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EIE77993.1 - 1.7e-05 24.5 0.1 3.3e-05 23.6 0.1 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Radical_SAM PF04055.16 EIE77994.1 - 0.01 16.0 0.0 0.012 15.7 0.0 1.3 1 0 0 1 1 1 0 Radical SAM superfamily Asp_protease_2 PF13650.1 EIE77995.1 - 5.5e-07 30.0 0.3 1e-06 29.1 0.2 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EIE77995.1 - 8.3e-06 25.5 0.0 1.3e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.5 EIE77995.1 - 0.078 12.5 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease DDE_3 PF13358.1 EIE77996.1 - 4.2e-16 58.9 0.0 8.3e-16 58.0 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE77996.1 - 5.3e-06 26.4 0.8 1.8e-05 24.6 0.8 1.8 2 0 0 2 2 2 1 Transposase NUDIX_4 PF14815.1 EIE77996.1 - 0.0078 15.6 0.3 0.013 14.9 0.2 1.4 1 0 0 1 1 1 1 NUDIX domain HTH_Tnp_Tc3_2 PF01498.13 EIE77997.1 - 1.2e-08 34.8 0.4 1.2e-08 34.8 0.3 2.1 1 1 1 2 2 2 1 Transposase HTH_29 PF13551.1 EIE77997.1 - 0.00063 19.8 1.7 0.0018 18.4 1.2 1.7 1 1 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_ISL3 PF13542.1 EIE77997.1 - 0.011 14.9 2.5 0.03 13.4 0.7 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_21 PF13276.1 EIE77997.1 - 0.046 13.7 1.1 0.6 10.1 0.0 2.3 2 0 0 2 2 2 0 HTH-like domain HTH_12 PF08461.5 EIE77997.1 - 0.062 13.0 0.1 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain HTH_32 PF13565.1 EIE77997.1 - 0.064 14.0 1.8 0.087 13.6 0.4 1.9 2 0 0 2 2 2 0 Homeodomain-like domain DUF569 PF04601.8 EIE77997.1 - 0.2 11.0 2.2 1.2 8.6 0.6 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF569) HTH_23 PF13384.1 EIE77997.1 - 0.26 10.9 3.3 3.2 7.5 0.3 2.5 2 0 0 2 2 2 0 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.1 EIE77998.1 - 0.028 13.6 0.0 0.067 12.3 0.0 1.5 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 GerE PF00196.14 EIE77998.1 - 0.036 13.3 0.0 0.054 12.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family HTH_23 PF13384.1 EIE77998.1 - 0.049 13.2 0.0 0.058 13.0 0.0 1.2 1 0 0 1 1 1 0 Homeodomain-like domain RVT_1 PF00078.22 EIE77999.1 - 1.4e-17 63.8 0.0 2.2e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EIE78000.1 - 1.7e-24 86.1 0.0 5.6e-24 84.5 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE78000.1 - 6.8e-17 61.5 0.0 1.3e-16 60.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE78000.1 - 3.7e-10 39.3 0.6 1.1e-09 37.8 0.4 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 EIE78000.1 - 0.00038 19.7 0.1 0.001 18.4 0.1 1.8 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger UBN2_2 PF14227.1 EIE78000.1 - 0.017 14.6 1.1 0.33 10.5 0.0 2.8 3 0 0 3 3 3 0 gag-polypeptide of LTR copia-type rve_3 PF13683.1 EIE78000.1 - 0.026 14.0 0.0 0.086 12.3 0.0 2.0 1 0 0 1 1 1 0 Integrase core domain UBN2 PF14223.1 EIE78000.1 - 0.062 13.0 0.6 0.16 11.7 0.1 1.9 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type rve PF00665.21 EIE78001.1 - 2.4e-23 82.5 0.0 5.5e-23 81.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 EIE78001.1 - 6.5e-12 44.9 0.2 1.2e-11 44.0 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 EIE78001.1 - 0.0029 16.9 0.1 0.006 15.9 0.0 1.6 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger HTH_Tnp_Tc3_2 PF01498.13 EIE78002.1 - 1.4e-09 37.8 0.4 1.4e-09 37.8 0.3 1.9 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 EIE78002.1 - 8.3e-06 25.9 0.7 1.2e-05 25.4 0.5 1.3 1 0 0 1 1 1 1 Winged helix-turn helix HTH_7 PF02796.10 EIE78002.1 - 6e-05 22.8 0.4 0.0055 16.5 0.0 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_23 PF13384.1 EIE78002.1 - 0.00016 21.2 0.3 0.0023 17.5 0.0 2.3 2 0 0 2 2 2 1 Homeodomain-like domain SPOR PF05036.8 EIE78002.1 - 0.097 12.8 0.2 0.95 9.6 0.1 2.3 1 1 1 2 2 2 0 Sporulation related domain HTH_28 PF13518.1 EIE78002.1 - 0.13 12.2 0.2 0.54 10.3 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain rve PF00665.21 EIE78003.1 - 5.2e-24 84.6 0.0 1.2e-23 83.5 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 EIE78003.1 - 1.8e-11 43.5 1.1 4.1e-11 42.3 0.7 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVT_1 PF00078.22 EIE78003.1 - 2.2e-09 36.9 0.0 4.8e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.5 EIE78003.1 - 0.00072 18.9 0.1 0.0018 17.6 0.1 1.8 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger rve_3 PF13683.1 EIE78003.1 - 0.0027 17.1 0.2 0.021 14.3 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain DUF2246 PF10229.4 EIE78003.1 - 0.044 13.0 0.1 0.085 12.1 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2246) Retrotrans_gag PF03732.12 EIE78004.1 - 0.00022 21.2 0.8 0.00051 20.0 0.6 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein Asp_protease_2 PF13650.1 EIE78004.1 - 0.0012 19.2 0.2 0.0028 18.1 0.2 1.7 1 0 0 1 1 1 1 Aspartyl protease UBN2_2 PF14227.1 EIE78004.1 - 0.0015 18.0 0.7 0.0092 15.5 0.0 2.3 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type Asp_protease PF09668.5 EIE78004.1 - 0.0073 15.8 0.2 0.037 13.5 0.1 2.1 1 1 0 1 1 1 1 Aspartyl protease UBN2 PF14223.1 EIE78004.1 - 0.021 14.6 0.1 0.064 13.0 0.1 1.8 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type RVP_2 PF08284.6 EIE78004.1 - 0.032 14.1 0.1 0.1 12.5 0.1 2.0 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-H2C2 PF09337.5 EIE78005.1 - 0.0031 16.8 0.1 0.0079 15.5 0.1 1.7 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger RNase_H PF00075.19 EIE78005.1 - 0.084 13.2 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 RNase H rve PF00665.21 EIE78006.1 - 5.1e-18 65.3 0.0 9.2e-18 64.4 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 EIE78006.1 - 2.1e-08 33.6 1.9 2.4e-08 33.5 0.1 2.1 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain BRE1 PF08647.6 EIE78006.1 - 5.8 6.9 13.1 3.2 7.7 7.2 2.0 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase RVT_1 PF00078.22 EIE78007.1 - 2.1e-11 43.6 0.5 1.1e-10 41.2 0.4 2.1 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP PF00077.15 EIE78007.1 - 0.0025 17.6 0.1 0.014 15.2 0.0 2.4 2 0 0 2 2 2 1 Retroviral aspartyl protease DUF2361 PF10153.4 EIE78007.1 - 0.0046 17.1 0.6 0.01 15.9 0.4 1.6 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2361) Asp_protease_2 PF13650.1 EIE78007.1 - 0.054 14.0 0.1 0.25 11.8 0.0 2.2 2 0 0 2 2 2 0 Aspartyl protease Retrotrans_gag PF03732.12 EIE78007.1 - 0.084 12.9 0.0 0.46 10.5 0.0 2.2 1 0 0 1 1 1 0 Retrotransposon gag protein DDE_3 PF13358.1 EIE78009.1 - 9.3e-22 77.3 0.3 1.4e-21 76.7 0.2 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE78009.1 - 3.3e-10 39.8 0.1 8.9e-10 38.5 0.1 1.8 1 0 0 1 1 1 1 Transposase rve PF00665.21 EIE78009.1 - 0.02 14.9 0.0 0.11 12.5 0.0 2.2 1 1 0 1 1 1 0 Integrase core domain HMG_box PF00505.14 EIE78009.1 - 0.074 13.3 1.2 0.35 11.1 0.6 2.3 2 1 0 2 2 2 0 HMG (high mobility group) box HMG_box_2 PF09011.5 EIE78009.1 - 0.087 13.2 0.5 0.087 13.2 0.3 2.1 2 0 0 2 2 2 0 HMG-box domain HTH_21 PF13276.1 EIE78009.1 - 0.091 12.7 0.1 1.5 8.8 0.0 2.5 2 0 0 2 2 2 0 HTH-like domain Retrotrans_gag PF03732.12 EIE78010.1 - 6.9e-07 29.2 1.8 3.3e-06 27.0 0.0 2.7 3 0 0 3 3 3 1 Retrotransposon gag protein UBN2_2 PF14227.1 EIE78010.1 - 1.7e-05 24.3 0.8 0.00021 20.8 0.1 2.7 2 1 0 2 2 2 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EIE78010.1 - 4.3e-05 23.2 1.9 0.083 12.6 0.0 3.0 3 1 0 3 3 3 2 gag-polypeptide of LTR copia-type HTH_Tnp_Tc3_2 PF01498.13 EIE78011.1 - 2.8e-07 30.4 0.1 4.6e-07 29.7 0.1 1.4 1 0 0 1 1 1 1 Transposase DUF483 PF04467.7 EIE78011.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF483) zf-CCHC PF00098.18 EIE78013.1 - 7.3e-06 25.6 7.6 0.018 14.9 0.3 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 EIE78013.1 - 0.0003 20.3 1.0 0.076 12.7 0.4 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-nanos PF05741.8 EIE78013.1 - 0.62 10.0 5.1 3.3 7.7 3.5 2.1 1 1 0 1 1 1 0 Nanos RNA binding domain IR1-M PF12185.3 EIE78015.1 - 1.9 8.2 4.2 0.34 10.6 0.1 1.8 2 0 0 2 2 2 0 Nup358/RanBP2 E3 ligase domain DDE_3 PF13358.1 EIE78016.1 - 2.4e-12 46.8 0.3 2.9e-12 46.5 0.2 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease NAGLU PF05089.7 EIE78016.1 - 0.046 12.4 0.0 0.057 12.1 0.0 1.2 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain Fungal_trans PF04082.13 EIE78017.1 - 1.1e-37 129.3 0.0 1.7e-37 128.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain CbiD PF01888.12 EIE78018.1 - 0.087 11.7 0.0 0.097 11.6 0.0 1.1 1 0 0 1 1 1 0 CbiD Atg14 PF10186.4 EIE78019.1 - 6.9e-09 35.0 10.9 1.8e-08 33.7 7.3 1.8 1 1 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 DUF4494 PF14902.1 EIE78019.1 - 0.67 9.5 4.8 1.4 8.4 3.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4494) Cortex-I_coil PF09304.5 EIE78019.1 - 1.2 9.2 12.5 2.7 8.0 6.5 2.3 1 1 1 2 2 2 0 Cortexillin I, coiled coil Ras PF00071.17 EIE78021.1 - 3.6e-43 146.7 0.0 4.2e-43 146.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIE78021.1 - 7.7e-18 65.1 0.0 9.3e-18 64.8 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 EIE78021.1 - 4.5e-07 29.2 0.0 5.7e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 EIE78021.1 - 4.7e-07 29.2 0.0 5.6e-07 28.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EIE78021.1 - 0.0062 15.7 0.0 0.0074 15.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit HIT PF01230.18 EIE78022.1 - 3.5e-25 88.3 0.1 4.7e-25 87.9 0.1 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EIE78022.1 - 1.4e-10 41.4 0.0 2e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 EIE78022.1 - 3.1e-06 26.8 0.3 5.2e-06 26.1 0.2 1.3 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 SDH_alpha PF03313.10 EIE78023.1 - 6e-103 343.7 0.4 7.9e-103 343.3 0.3 1.1 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.10 EIE78023.1 - 3.9e-41 140.7 0.4 1.3e-30 106.5 0.1 2.5 1 1 1 2 2 2 2 Serine dehydratase beta chain MmgE_PrpD PF03972.9 EIE78023.1 - 0.025 12.7 1.5 0.036 12.2 1.0 1.1 1 0 0 1 1 1 0 MmgE/PrpD family Abhydrolase_6 PF12697.2 EIE78024.1 - 7.3e-22 78.3 0.0 8.7e-22 78.1 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIE78024.1 - 1.3e-12 47.6 0.0 2.5e-12 46.7 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EIE78024.1 - 1.5e-06 27.9 0.0 2.9e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 EIE78024.1 - 2.4e-06 27.3 0.0 5.8e-05 22.7 0.0 2.2 1 1 0 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.13 EIE78024.1 - 0.0037 16.5 0.0 0.065 12.4 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family PGAP1 PF07819.8 EIE78024.1 - 0.0038 16.8 0.0 0.0082 15.7 0.0 1.6 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_3 PF07859.8 EIE78024.1 - 0.005 16.4 0.0 0.017 14.7 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2920 PF11144.3 EIE78024.1 - 0.031 13.3 1.9 1.3 7.9 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2920) Esterase PF00756.15 EIE78024.1 - 0.16 11.3 0.0 0.34 10.2 0.0 1.5 1 0 0 1 1 1 0 Putative esterase Nup54 PF13874.1 EIE78025.1 - 2e-32 111.7 3.4 2e-32 111.7 2.3 1.7 1 1 0 1 1 1 1 Nucleoporin complex subunit 54 Polysacc_deac_1 PF01522.16 EIE78026.1 - 1.1e-07 31.5 0.1 7.3e-07 28.8 0.1 2.2 1 1 0 1 1 1 1 Polysaccharide deacetylase Sec7 PF01369.15 EIE78027.1 - 3.5e-57 193.1 0.5 6.7e-57 192.2 0.3 1.5 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 EIE78027.1 - 3.4e-16 59.1 0.9 3e-09 36.5 0.0 3.0 3 0 0 3 3 3 2 Guanine nucleotide exchange factor in Golgi transport N-terminal Complex1_LYR_1 PF13232.1 EIE78028.1 - 3.3e-06 27.2 0.2 3.3e-06 27.2 0.1 1.4 2 0 0 2 2 2 1 Complex1_LYR-like Complex1_LYR PF05347.10 EIE78028.1 - 3.3e-06 26.7 0.5 6.5e-06 25.8 0.3 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) TPK_catalytic PF04263.11 EIE78028.1 - 0.0093 15.5 0.2 0.022 14.3 0.0 1.7 1 1 1 2 2 2 1 Thiamin pyrophosphokinase, catalytic domain ING PF12998.2 EIE78028.1 - 0.54 10.5 5.1 0.19 11.9 1.6 1.6 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding DUF349 PF03993.7 EIE78028.1 - 6.4 7.0 7.1 1.8 8.7 2.1 2.1 2 1 1 3 3 3 0 Domain of Unknown Function (DUF349) CheX PF13690.1 EIE78029.1 - 0.21 11.4 2.2 4.2 7.2 0.1 3.1 2 1 1 3 3 3 0 Chemotaxis phosphatase CheX ArsA_ATPase PF02374.10 EIE78031.1 - 5.6e-106 354.0 0.4 1.1e-105 353.0 0.3 1.4 1 0 0 1 1 1 1 Anion-transporting ATPase CTDII PF01556.13 EIE78031.1 - 1.9e-21 75.7 0.4 4.1e-17 61.8 0.0 2.8 3 0 0 3 3 3 2 DnaJ C terminal domain CbiA PF01656.18 EIE78031.1 - 4.6e-14 52.2 0.0 8.8e-14 51.3 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DnaJ_CXXCXGXG PF00684.14 EIE78031.1 - 1.3e-13 50.7 18.6 1.3e-13 50.7 12.9 2.2 2 0 0 2 2 2 1 DnaJ central domain DnaJ PF00226.26 EIE78031.1 - 1.8e-07 30.7 0.3 4.5e-07 29.5 0.2 1.7 1 0 0 1 1 1 1 DnaJ domain AAA_31 PF13614.1 EIE78031.1 - 1.8e-07 31.1 0.0 5.7e-07 29.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain SRP54 PF00448.17 EIE78031.1 - 0.00067 19.1 0.9 0.0036 16.7 0.0 2.5 2 1 0 3 3 3 1 SRP54-type protein, GTPase domain AAA_25 PF13481.1 EIE78031.1 - 0.00074 18.9 0.0 0.0021 17.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain Fer4_NifH PF00142.13 EIE78031.1 - 0.00096 18.4 0.0 0.00096 18.4 0.0 1.8 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family YhjQ PF06564.7 EIE78031.1 - 0.0075 15.6 0.0 0.016 14.5 0.0 1.5 2 0 0 2 2 2 1 YhjQ protein MipZ PF09140.6 EIE78031.1 - 0.13 11.3 0.0 0.24 10.4 0.0 1.5 1 0 0 1 1 1 0 ATPase MipZ HypA PF01155.14 EIE78031.1 - 6.6 6.4 14.2 1.3 8.7 1.8 2.9 2 1 1 3 3 3 0 Hydrogenase expression/synthesis hypA family Acetyltransf_1 PF00583.19 EIE78032.1 - 4.6e-06 26.5 0.5 4.1e-05 23.5 0.3 2.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EIE78032.1 - 1.9e-05 24.7 0.1 0.099 12.7 0.0 2.7 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EIE78032.1 - 0.00019 21.5 0.1 0.38 10.9 0.0 2.5 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EIE78032.1 - 0.01 15.9 0.3 2.7 8.1 0.2 2.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain PGA2 PF07543.7 EIE78032.1 - 0.044 13.5 0.0 0.044 13.5 0.0 2.5 3 0 0 3 3 3 0 Protein trafficking PGA2 SPX PF03105.14 EIE78033.1 - 2.5e-40 138.9 5.1 5.3e-40 137.9 3.5 1.6 1 1 0 1 1 1 1 SPX domain Na_sulph_symp PF00939.14 EIE78033.1 - 8e-29 100.8 36.8 1.1e-28 100.3 25.5 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 EIE78033.1 - 3.3e-12 45.6 42.9 2.2e-11 42.9 15.4 2.4 1 1 1 2 2 2 2 Citrate transporter Glyco_hydro_28 PF00295.12 EIE78034.1 - 7.4e-67 225.6 28.9 9.1e-67 225.3 20.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 APG6 PF04111.7 EIE78035.1 - 0.021 13.8 8.5 0.78 8.7 6.1 2.0 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF342 PF03961.8 EIE78035.1 - 0.062 11.7 4.1 0.069 11.5 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) IncA PF04156.9 EIE78035.1 - 0.15 11.6 5.1 0.21 11.1 3.6 1.2 1 0 0 1 1 1 0 IncA protein YlqD PF11068.3 EIE78035.1 - 0.58 10.2 9.3 1.1 9.3 6.5 1.5 1 0 0 1 1 1 0 YlqD protein DivIC PF04977.10 EIE78035.1 - 5.4 6.5 10.1 62 3.1 7.0 2.3 1 1 0 1 1 1 0 Septum formation initiator Ribosomal_S16 PF00886.14 EIE78036.1 - 7.5e-27 92.8 0.1 9.6e-27 92.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S16 DUF1446 PF07287.6 EIE78037.1 - 6.7e-110 366.9 0.2 8.7e-110 366.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1446) Lactamase_B PF00753.22 EIE78037.1 - 1.6e-16 60.5 0.0 3.3e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Rhodanese PF00581.15 EIE78037.1 - 4.9e-16 59.0 0.0 1.5e-15 57.4 0.0 1.9 1 0 0 1 1 1 1 Rhodanese-like domain Pkinase PF00069.20 EIE78038.1 - 7.8e-34 116.9 0.0 9e-34 116.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE78038.1 - 6e-30 104.1 0.0 7.6e-30 103.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE78038.1 - 4.3e-05 22.6 0.0 5.6e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EIE78038.1 - 0.0069 15.4 0.0 0.0091 15.0 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIE78038.1 - 0.097 12.3 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Peroxidase_2 PF01328.12 EIE78039.1 - 3e-15 55.7 0.0 4.2e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 Hist_deacetyl PF00850.14 EIE78040.1 - 1.1e-69 235.0 5.9 3e-55 187.7 0.1 2.9 2 1 1 3 3 3 2 Histone deacetylase domain Paramyxo_ncap PF00973.14 EIE78040.1 - 1.3 7.6 7.2 2 7.0 5.0 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein ELO PF01151.13 EIE78041.1 - 5.1e-59 199.5 31.3 6.2e-59 199.3 21.7 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family DUF1689 PF07954.6 EIE78041.1 - 2.8 7.7 6.6 1.2 8.9 2.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1689) polyprenyl_synt PF00348.12 EIE78042.1 - 3.7e-52 176.7 0.2 3.6e-49 166.9 0.1 2.1 2 0 0 2 2 2 2 Polyprenyl synthetase Myc_N PF01056.13 EIE78043.1 - 0.031 13.4 1.6 0.038 13.1 1.1 1.1 1 0 0 1 1 1 0 Myc amino-terminal region AF1Q PF15017.1 EIE78043.1 - 5 7.0 6.8 7 6.6 3.8 1.8 1 1 1 2 2 2 0 Drug resistance and apoptosis regulator HTH_29 PF13551.1 EIE78045.1 - 0.047 13.8 0.0 0.079 13.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix Terminase_5 PF06056.7 EIE78045.1 - 0.047 13.2 0.1 0.67 9.5 0.1 2.3 2 0 0 2 2 2 0 Putative ATPase subunit of terminase (gpP-like) Orn_Arg_deC_N PF02784.11 EIE78046.1 - 1.3e-78 263.7 0.0 1.6e-78 263.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 EIE78046.1 - 1.5e-33 114.9 0.1 2.6e-33 114.1 0.1 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.19 EIE78046.1 - 0.064 12.5 0.0 0.14 11.4 0.0 1.5 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel F5_F8_type_C PF00754.20 EIE78047.1 - 2.8e-08 33.6 0.0 3.4e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 F5/8 type C domain APC10 PF03256.11 EIE78047.1 - 0.00051 19.6 0.0 0.00067 19.2 0.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) NAD_kinase PF01513.16 EIE78048.1 - 8.9e-30 103.4 0.0 1.5e-29 102.6 0.0 1.4 1 1 0 1 1 1 1 ATP-NAD kinase Pkinase PF00069.20 EIE78049.1 - 1.8e-52 178.0 0.0 3e-52 177.3 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE78049.1 - 2.1e-23 82.7 0.1 3.2e-23 82.1 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE78049.1 - 5.1e-06 25.6 1.6 0.00049 19.1 0.0 2.2 1 1 1 2 2 2 2 Kinase-like CUT PF02376.10 EIE78051.1 - 0.018 14.8 0.0 0.021 14.5 0.0 1.1 1 0 0 1 1 1 0 CUT domain ATP-synt_C PF00137.16 EIE78055.1 - 0.42 10.5 7.8 0.88 9.5 0.5 2.5 2 1 0 2 2 2 0 ATP synthase subunit C FAM163 PF15069.1 EIE78055.1 - 7.6 7.0 11.6 3e+02 1.9 8.0 2.4 1 1 0 1 1 1 0 FAM163 family zf-H2C2_2 PF13465.1 EIE78056.1 - 3.3e-12 46.0 14.4 6.4e-09 35.6 0.8 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 EIE78056.1 - 2.4e-11 43.2 27.0 2.2e-07 30.7 1.4 4.0 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIE78056.1 - 1.6e-06 28.0 25.1 0.00046 20.3 0.7 4.0 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EIE78056.1 - 0.039 13.8 9.1 5.4 7.0 0.2 4.0 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2HC_2 PF13913.1 EIE78056.1 - 0.33 10.6 13.8 0.44 10.2 0.8 3.7 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Zn_Tnp_IS1595 PF12760.2 EIE78056.1 - 0.46 10.3 11.3 0.63 9.8 1.4 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain C1_4 PF07975.7 EIE78056.1 - 0.86 9.6 6.2 1.5 8.8 0.2 2.6 1 1 1 2 2 2 0 TFIIH C1-like domain zf-C2H2_jaz PF12171.3 EIE78056.1 - 4.6 7.4 19.8 0.96 9.6 0.4 4.0 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.5 EIE78056.1 - 6.3 6.8 9.6 9 6.3 0.3 3.3 2 1 1 3 3 3 0 Zinc ribbon domain Zn_ribbon_recom PF13408.1 EIE78056.1 - 7.7 6.8 12.9 1 9.7 4.1 2.6 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain HLH PF00010.21 EIE78058.1 - 1.1e-12 47.4 2.1 2.2e-12 46.4 1.5 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Myc-LZ PF02344.10 EIE78058.1 - 0.1 12.2 2.7 1.9 8.1 0.2 2.4 2 0 0 2 2 2 0 Myc leucine zipper domain Cluap1 PF10234.4 EIE78058.1 - 0.64 9.1 12.0 0.86 8.7 8.3 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 SNARE PF05739.14 EIE78059.1 - 1.8e-13 49.9 3.3 1.8e-13 49.9 2.3 2.8 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 EIE78059.1 - 6.6e-11 42.2 6.2 6.6e-11 42.2 4.3 3.2 2 1 1 3 3 3 1 Syntaxin tRNA_synt_1c_R1 PF04558.10 EIE78059.1 - 0.0031 17.0 0.8 0.0031 17.0 0.6 2.1 3 0 0 3 3 3 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 rRNA_proc-arch PF13234.1 EIE78059.1 - 0.014 14.5 6.4 0.04 13.0 1.1 2.3 2 0 0 2 2 2 0 rRNA-processing arch domain OppC_N PF12911.2 EIE78059.1 - 0.016 14.5 1.8 0.036 13.4 1.2 1.6 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Sec20 PF03908.8 EIE78059.1 - 0.027 14.1 0.6 0.027 14.1 0.4 3.8 2 2 2 4 4 4 0 Sec20 Rifin_STEVOR PF02009.11 EIE78059.1 - 0.23 11.0 15.8 4.8 6.7 10.3 2.1 1 1 1 2 2 2 0 Rifin/stevor family Flu_NS2 PF00601.14 EIE78059.1 - 0.24 11.6 6.5 2.2 8.5 0.3 2.7 2 1 0 2 2 2 0 Influenza non-structural protein (NS2) DASH_Dam1 PF08653.5 EIE78059.1 - 0.3 10.8 2.5 19 5.1 0.0 2.8 2 1 1 3 3 3 0 DASH complex subunit Dam1 NPV_P10 PF05531.7 EIE78059.1 - 1.2 9.4 12.1 5.1 7.4 1.0 3.4 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF479 PF04336.7 EIE78059.1 - 5.2 7.2 7.3 7.2 6.7 0.7 3.5 1 1 3 4 4 4 0 Protein of unknown function, DUF479 EF1_GNE PF00736.14 EIE78060.1 - 3.1e-32 110.1 1.1 5.9e-32 109.2 0.8 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 EIE78060.1 - 5.8e-13 48.7 5.4 5.8e-13 48.7 3.7 2.3 3 0 0 3 3 3 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.1 EIE78060.1 - 0.00095 19.6 0.0 0.0021 18.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EIE78060.1 - 0.013 15.4 0.2 0.063 13.2 0.0 2.2 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain DUF2777 PF10949.3 EIE78060.1 - 0.11 12.1 2.1 0.34 10.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2777) KCl_Cotrans_1 PF03522.10 EIE78060.1 - 1.7 8.2 4.2 0.64 9.5 0.2 2.2 2 0 0 2 2 2 0 K-Cl Co-transporter type 1 (KCC1) PALP PF00291.20 EIE78061.1 - 4.3e-75 252.7 0.3 5.5e-75 252.4 0.2 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 EIE78061.1 - 8.5e-35 118.2 0.0 3.4e-16 58.6 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase Ribosomal_S17 PF00366.15 EIE78062.1 - 1.6e-24 85.6 0.9 1.9e-24 85.4 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S17 Glyco_hydro_31 PF01055.21 EIE78063.1 - 5.7e-154 513.1 10.5 8.2e-154 512.6 7.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EIE78063.1 - 2.8e-23 81.5 0.5 1.7e-22 79.0 0.0 2.5 2 0 0 2 2 2 1 Galactose mutarotase-like HEAT PF02985.17 EIE78064.1 - 8.7e-17 59.6 9.4 0.0032 17.4 0.1 7.4 7 0 0 7 7 7 4 HEAT repeat HEAT_2 PF13646.1 EIE78064.1 - 2e-10 40.8 0.5 2.4e-05 24.5 0.0 5.6 4 2 2 6 6 6 2 HEAT repeats HEAT_EZ PF13513.1 EIE78064.1 - 0.0016 18.8 0.6 0.63 10.6 0.0 4.5 4 0 0 4 4 4 1 HEAT-like repeat Cnd1 PF12717.2 EIE78064.1 - 0.022 14.6 4.3 0.42 10.4 0.0 3.8 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 B12D PF06522.6 EIE78065.1 - 6e-19 67.5 0.0 7.4e-19 67.2 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit Voltage_CLC PF00654.15 EIE78065.1 - 0.11 11.4 0.0 0.12 11.3 0.0 1.0 1 0 0 1 1 1 0 Voltage gated chloride channel HLH PF00010.21 EIE78066.1 - 3.5e-12 45.8 4.0 8.3e-12 44.6 0.7 2.3 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Phage_lambd_GpG PF06894.6 EIE78066.1 - 0.093 12.3 1.7 0.15 11.6 0.2 1.8 1 1 1 2 2 2 0 Bacteriophage lambda minor tail protein (GpG) Epsilon_antitox PF08998.6 EIE78066.1 - 1.1 9.3 4.9 0.99 9.4 2.8 1.5 1 1 0 1 1 1 0 Bacterial epsilon antitoxin HAUS6_N PF14661.1 EIE78066.1 - 1.7 7.9 10.1 6.8 5.9 6.5 1.9 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF1492 PF07374.6 EIE78066.1 - 2.6 8.1 8.0 5.6 7.1 0.6 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1492) YcbB PF08664.5 EIE78066.1 - 3.9 7.2 7.3 0.95 9.2 0.5 2.0 1 1 1 2 2 2 0 YcbB domain Not3 PF04065.10 EIE78067.1 - 2.9e-98 327.7 27.7 4.6e-98 327.1 19.2 1.3 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 EIE78067.1 - 2.8e-46 156.7 11.7 2.8e-46 156.7 8.1 2.1 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family CK2S PF15011.1 EIE78067.1 - 0.048 13.4 1.8 0.19 11.4 0.2 2.6 2 1 1 3 3 3 0 Casein Kinase 2 substrate DUF948 PF06103.6 EIE78067.1 - 0.33 10.8 7.5 2.1 8.2 0.2 3.7 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Syntaxin PF00804.20 EIE78067.1 - 2.3 8.4 13.7 0.48 10.6 5.4 2.7 1 1 1 2 2 2 0 Syntaxin VTC PF09359.5 EIE78068.1 - 2.2e-87 292.6 0.0 3.7e-87 291.9 0.0 1.4 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 EIE78068.1 - 5.3e-25 88.7 4.1 1.8e-11 44.3 0.1 3.4 1 1 1 2 2 2 2 SPX domain Sda PF08970.5 EIE78068.1 - 0.018 14.5 0.2 0.95 9.0 0.2 3.2 3 0 0 3 3 3 0 Sporulation inhibitor A Bac_globin PF01152.16 EIE78069.1 - 0.0013 18.6 0.0 0.0016 18.4 0.0 1.2 1 0 0 1 1 1 1 Bacterial-like globin AdoHcyase PF05221.12 EIE78069.1 - 0.084 11.8 0.0 0.12 11.3 0.0 1.2 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase zf-HC5HC2H PF13771.1 EIE78070.1 - 3e-11 43.2 3.2 3e-11 43.2 2.2 3.6 3 1 1 4 4 4 1 PHD-like zinc-binding domain N6_N4_Mtase PF01555.13 EIE78070.1 - 7.5e-09 35.4 18.5 5.1e-05 22.8 0.0 5.4 5 1 0 5 5 5 3 DNA methylase Methyltransf_26 PF13659.1 EIE78070.1 - 5.4e-08 32.8 0.0 3.4e-07 30.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain zf-HC5HC2H_2 PF13832.1 EIE78070.1 - 1.4e-06 28.2 3.3 1.4e-06 28.2 2.3 2.9 3 0 0 3 3 3 1 PHD-zinc-finger like domain MBT PF02820.13 EIE78070.1 - 9.5e-06 25.4 0.7 0.13 12.2 0.0 3.6 3 0 0 3 3 3 2 mbt repeat HHH_8 PF14716.1 EIE78071.1 - 2.5e-12 46.7 0.2 4.4e-12 45.9 0.1 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.4 EIE78071.1 - 2.5e-06 26.9 0.1 1.1e-05 24.9 0.0 2.0 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda SET PF00856.23 EIE78072.1 - 1.7e-09 38.2 0.0 8.1e-09 35.9 0.0 2.2 3 1 0 3 3 3 1 SET domain zf-MYND PF01753.13 EIE78072.1 - 0.00017 21.3 10.5 0.00017 21.3 7.3 3.5 2 1 0 2 2 2 1 MYND finger zf-Mss51 PF13824.1 EIE78072.1 - 0.00075 19.3 12.2 0.009 15.8 3.7 3.5 3 0 0 3 3 3 1 Zinc-finger of mitochondrial splicing suppressor 51 Zn_Tnp_IS1595 PF12760.2 EIE78072.1 - 0.1 12.4 0.0 0.1 12.4 0.0 3.1 3 1 0 3 3 3 0 Transposase zinc-ribbon domain TPR_11 PF13414.1 EIE78072.1 - 0.15 11.6 2.0 0.42 10.2 0.4 2.4 2 1 0 2 2 2 0 TPR repeat ATP-synt_E_2 PF08112.6 EIE78072.1 - 0.28 11.2 4.7 0.72 9.9 1.1 2.9 3 0 0 3 3 3 0 ATP synthase epsilon subunit AMP-binding PF00501.23 EIE78074.1 - 1.1e-24 86.5 0.2 1.4e-24 86.2 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme MFS_1 PF07690.11 EIE78075.1 - 6.7e-53 179.6 46.2 1.5e-52 178.4 30.6 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EIE78075.1 - 1.2e-17 63.4 13.5 2.1e-17 62.5 9.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EIE78075.1 - 2e-13 49.7 14.1 2e-13 49.7 9.8 3.4 2 1 0 3 3 3 2 Sugar (and other) transporter DUF3377 PF11857.3 EIE78075.1 - 6.8 6.3 10.0 0.81 9.3 0.4 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF3377) OAD_gamma PF04277.8 EIE78075.1 - 7.6 6.9 6.9 5.7 7.3 0.1 3.3 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain L31 PF09784.4 EIE78076.1 - 5.4e-38 129.2 0.1 6e-38 129.0 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 UPF0029 PF01205.14 EIE78077.1 - 4.5e-19 68.1 0.2 1.9e-17 62.9 0.2 2.2 1 1 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.17 EIE78077.1 - 5.7e-19 68.0 0.4 8.9e-19 67.4 0.3 1.3 1 0 0 1 1 1 1 RWD domain NACHT PF05729.7 EIE78077.1 - 0.091 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 NACHT domain SRF-TF PF00319.13 EIE78078.1 - 5.9e-22 76.6 0.0 1e-21 75.9 0.0 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF4344 PF14247.1 EIE78078.1 - 0.04 13.5 2.6 0.74 9.4 0.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4344) HEAT PF02985.17 EIE78079.1 - 4.3e-13 48.1 0.1 0.0088 16.0 0.0 5.6 6 0 0 6 6 6 3 HEAT repeat HEAT_2 PF13646.1 EIE78079.1 - 7.4e-11 42.1 0.2 4.7e-06 26.7 0.0 4.0 2 2 2 4 4 4 2 HEAT repeats Cnd1 PF12717.2 EIE78079.1 - 0.00046 20.0 4.6 0.0015 18.4 0.2 3.2 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Cohesin_HEAT PF12765.2 EIE78079.1 - 0.0017 18.2 0.0 0.0072 16.2 0.0 2.2 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion Thioredoxin_5 PF13743.1 EIE78081.1 - 0.07 12.6 0.2 0.11 12.0 0.2 1.3 1 0 0 1 1 1 0 Thioredoxin F-box-like PF12937.2 EIE78082.1 - 0.0065 16.1 0.7 0.017 14.8 0.5 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIE78082.1 - 0.013 15.1 1.1 0.035 13.7 0.7 1.8 1 0 0 1 1 1 0 F-box domain Ribosomal_L32e PF01655.13 EIE78083.1 - 2.3e-47 159.5 1.5 2.8e-47 159.3 1.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 BTB_2 PF02214.17 EIE78084.1 - 8.1e-16 58.0 0.4 1.8e-15 56.9 0.3 1.6 1 0 0 1 1 1 1 BTB/POZ domain Ras PF00071.17 EIE78085.1 - 1.5e-36 125.2 0.7 4.4e-19 68.4 0.0 2.1 1 1 1 2 2 2 2 Ras family Arf PF00025.16 EIE78085.1 - 9.4e-05 21.7 0.2 0.0026 17.0 0.0 2.1 1 1 1 2 2 2 1 ADP-ribosylation factor family Miro PF08477.8 EIE78085.1 - 0.052 14.0 0.1 1.3 9.4 0.0 2.4 1 1 1 2 2 2 0 Miro-like protein YopJ PF03421.11 EIE78085.1 - 0.09 12.6 0.0 0.27 11.0 0.0 1.7 1 1 1 2 2 2 0 YopJ Serine/Threonine acetyltransferase Reo_sigmaC PF04582.7 EIE78086.1 - 0.0065 15.6 4.5 0.0077 15.4 2.5 1.5 1 1 0 1 1 1 1 Reovirus sigma C capsid protein CbiC PF02570.10 EIE78086.1 - 0.45 9.9 3.6 0.72 9.2 1.0 2.2 2 1 0 2 2 2 0 Precorrin-8X methylmutase DUF948 PF06103.6 EIE78086.1 - 0.61 9.9 13.2 0.52 10.2 0.5 3.8 2 2 3 5 5 5 0 Bacterial protein of unknown function (DUF948) Laminin_I PF06008.9 EIE78086.1 - 1.2 8.3 26.2 0.39 9.9 6.6 3.2 2 1 1 3 3 3 0 Laminin Domain I DUF1515 PF07439.6 EIE78086.1 - 1.6 8.5 4.1 6 6.7 0.4 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) MCC-bdg_PDZ PF10506.4 EIE78086.1 - 2.1 8.2 13.1 0.57 10.0 0.2 3.2 3 1 0 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Sec2p PF06428.6 EIE78086.1 - 2.9 7.8 24.1 0.56 10.0 0.2 3.1 1 1 2 3 3 3 0 GDP/GTP exchange factor Sec2p DASH_Dam1 PF08653.5 EIE78086.1 - 9 6.1 7.0 12 5.7 0.1 3.5 3 0 0 3 3 3 0 DASH complex subunit Dam1 APG6 PF04111.7 EIE78086.1 - 10 5.0 36.6 3.6 6.5 10.7 3.0 1 1 1 2 2 2 0 Autophagy protein Apg6 Ribosomal_L14 PF00238.14 EIE78087.1 - 1.1e-34 118.8 0.0 1.2e-34 118.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Ank_2 PF12796.2 EIE78088.1 - 6.5e-68 225.1 13.7 3.8e-24 84.8 0.1 4.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EIE78088.1 - 1.8e-42 141.0 8.5 1.7e-06 27.5 0.0 8.4 9 0 0 9 9 9 7 Ankyrin repeat Ank_4 PF13637.1 EIE78088.1 - 5.7e-40 135.0 3.3 1.4e-14 54.1 0.0 5.6 5 0 0 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIE78088.1 - 7.3e-34 112.4 9.7 0.00014 21.7 0.0 9.7 10 0 0 10 10 10 6 Ankyrin repeat Ank_5 PF13857.1 EIE78088.1 - 1.3e-32 111.0 11.6 2.4e-08 33.9 0.0 8.4 2 1 7 9 9 9 7 Ankyrin repeats (many copies) SPX PF03105.14 EIE78088.1 - 6.1e-29 101.6 16.6 5e-17 62.5 3.9 2.4 1 1 1 2 2 2 2 SPX domain GDPD PF03009.12 EIE78088.1 - 8.7e-20 71.3 0.0 4.3e-19 69.0 0.0 1.9 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family EzrA PF06160.7 EIE78088.1 - 0.0027 15.9 1.7 0.0039 15.4 1.2 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA FAD_binding_3 PF01494.14 EIE78089.1 - 2e-21 76.4 1.0 2.7e-21 76.0 0.7 1.2 1 0 0 1 1 1 1 FAD binding domain SE PF08491.5 EIE78089.1 - 0.06 12.1 0.0 0.083 11.7 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase OTCace_N PF02729.16 EIE78090.1 - 2.8e-44 150.2 0.2 4.5e-44 149.5 0.1 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 EIE78090.1 - 7.5e-44 149.3 0.0 1.5e-43 148.4 0.0 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Lustrin_cystein PF14625.1 EIE78090.1 - 1.3 9.1 4.0 1 9.5 0.5 2.1 2 0 0 2 2 2 0 Lustrin, cysteine-rich repeated domain PGM_PMM_I PF02878.11 EIE78091.1 - 1.6e-17 63.2 0.1 4.3e-08 32.7 0.0 3.9 2 1 2 4 4 4 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 EIE78091.1 - 6e-13 49.0 0.9 1.4e-11 44.6 0.0 3.3 3 1 0 3 3 3 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EIE78091.1 - 3.2e-11 43.0 0.2 1.1e-10 41.3 0.1 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.11 EIE78091.1 - 0.01 15.8 0.6 0.035 14.1 0.4 2.0 1 1 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III GTP-bdg_N PF13167.1 EIE78091.1 - 0.098 12.7 0.0 0.32 11.1 0.0 1.8 1 0 0 1 1 1 0 GTP-binding GTPase N-terminal SPRY PF00622.23 EIE78093.1 - 9.9e-27 93.4 0.6 1.7e-26 92.7 0.4 1.4 1 0 0 1 1 1 1 SPRY domain CLTH PF10607.4 EIE78093.1 - 1.1e-08 34.9 0.2 1.8e-08 34.2 0.1 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 EIE78093.1 - 5.5e-06 25.9 0.9 1.1e-05 24.9 0.1 2.0 2 0 0 2 2 2 1 LisH MFS_1 PF07690.11 EIE78094.1 - 3.3e-51 174.0 48.2 9e-51 172.6 32.3 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EIE78094.1 - 1.4e-17 63.1 14.6 2.5e-17 62.3 10.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EIE78094.1 - 1.9e-13 49.8 16.1 1.9e-13 49.8 11.2 4.0 3 2 1 4 4 4 2 Sugar (and other) transporter DUF3377 PF11857.3 EIE78094.1 - 0.4 10.3 7.6 0.41 10.3 0.2 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3377) AMP-binding PF00501.23 EIE78095.1 - 8.3e-87 291.2 0.0 1e-86 290.9 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EIE78095.1 - 1.9e-11 44.7 0.0 4.2e-11 43.6 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain FAM178 PF14816.1 EIE78096.1 - 2.8e-08 32.8 4.6 2.8e-08 32.8 3.2 2.8 2 1 0 2 2 2 1 Family of unknown function, FAM178 Birna_VP5 PF03042.9 EIE78096.1 - 0.036 13.5 1.8 0.15 11.5 0.0 2.6 2 1 1 3 3 3 0 Birnavirus VP5 protein DUF2183 PF09949.4 EIE78097.1 - 1.4e-32 111.6 0.1 7e-32 109.3 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) LNS2 PF08235.8 EIE78097.1 - 0.0019 17.7 0.0 0.0071 15.9 0.0 1.8 1 1 1 2 2 2 1 LNS2 (Lipin/Ned1/Smp2) EF-hand_6 PF13405.1 EIE78097.1 - 0.13 12.1 0.2 0.46 10.4 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain DDOST_48kD PF03345.9 EIE78098.1 - 3.2e-123 411.4 4.8 3.7e-123 411.2 3.3 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta SUR7 PF06687.7 EIE78099.1 - 1.9e-16 60.3 13.9 3e-16 59.6 9.4 1.5 1 1 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 EIE78099.1 - 3.1e-05 23.7 9.5 4.3e-05 23.2 6.6 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Orbi_NS3 PF01616.11 EIE78099.1 - 0.061 12.2 2.2 0.13 11.1 1.0 1.7 1 1 1 2 2 2 0 Orbivirus NS3 Glycophorin_A PF01102.13 EIE78099.1 - 0.13 11.9 0.3 0.22 11.3 0.2 1.4 1 0 0 1 1 1 0 Glycophorin A DUF2768 PF10966.3 EIE78099.1 - 1.1 9.4 14.5 0.09 12.9 5.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2768) 2TM PF13239.1 EIE78099.1 - 1.9 8.6 5.1 0.82 9.7 0.2 2.3 1 1 1 2 2 2 0 2TM domain DUF4282 PF14110.1 EIE78099.1 - 2.1 8.6 12.5 14 5.9 8.7 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4282) Renin_r PF07850.9 EIE78099.1 - 7 7.0 6.9 0.96 9.8 1.1 2.1 1 1 1 2 2 2 0 Renin receptor-like protein EmrE PF13536.1 EIE78101.1 - 0.012 15.7 11.4 0.012 15.7 7.9 3.6 3 1 1 4 4 4 0 Multidrug resistance efflux transporter FA_hydroxylase PF04116.8 EIE78102.1 - 2.2e-07 31.2 23.4 2.2e-07 31.2 16.2 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF3816 PF12822.2 EIE78102.1 - 0.87 9.4 8.3 0.18 11.6 0.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3816) F-box-like PF12937.2 EIE78103.1 - 7.6e-11 41.5 0.5 7.6e-11 41.5 0.4 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EIE78103.1 - 5.1e-08 32.3 1.2 1e-07 31.4 0.0 2.1 2 0 0 2 2 2 1 F-box domain Ras PF00071.17 EIE78105.1 - 2e-46 157.3 0.1 4.7e-46 156.1 0.1 1.6 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIE78105.1 - 1e-07 32.4 0.8 4.3e-07 30.4 0.0 2.5 2 1 0 2 2 2 1 Miro-like protein Arf PF00025.16 EIE78105.1 - 8e-07 28.4 1.7 1.4e-06 27.6 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EIE78105.1 - 0.0041 16.5 0.0 0.011 15.1 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LRR_5 PF13306.1 EIE78105.1 - 0.84 9.3 7.9 1.7 8.3 3.2 2.3 1 1 0 1 1 1 0 Leucine rich repeats (6 copies) FH2 PF02181.18 EIE78106.1 - 5.1e-62 209.8 22.3 5e-58 196.7 0.1 3.3 2 2 1 3 3 3 2 Formin Homology 2 Domain Drf_GBD PF06371.8 EIE78106.1 - 2.8e-30 105.0 10.5 5.5e-30 104.1 0.4 3.8 2 1 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 EIE78106.1 - 4e-24 85.1 0.0 4e-24 85.1 0.0 2.9 5 0 0 5 5 5 1 Diaphanous FH3 Domain HALZ PF02183.13 EIE78106.1 - 0.00025 20.6 6.1 0.0011 18.6 0.1 3.4 2 1 1 3 3 3 1 Homeobox associated leucine zipper FlaC_arch PF05377.6 EIE78106.1 - 0.0097 15.7 8.7 0.027 14.3 0.3 4.4 4 0 0 4 4 4 1 Flagella accessory protein C (FlaC) DUF2730 PF10805.3 EIE78106.1 - 0.22 11.2 5.9 0.073 12.8 0.4 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) DivIC PF04977.10 EIE78106.1 - 9.3 5.8 18.1 0.028 13.9 0.8 3.5 2 1 1 3 3 3 0 Septum formation initiator RAI16-like PF10257.4 EIE78107.1 - 4.1e-27 95.0 0.6 6.8e-27 94.3 0.4 1.3 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein SNAP PF14938.1 EIE78108.1 - 2.1e-96 322.4 13.2 2.4e-96 322.2 9.1 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 EIE78108.1 - 7.6e-07 28.9 13.1 5.9e-05 22.9 2.0 3.4 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 EIE78108.1 - 5.6e-06 25.9 18.1 0.00013 21.5 2.3 4.4 1 1 2 3 3 3 1 TPR repeat TPR_7 PF13176.1 EIE78108.1 - 4.6e-05 22.9 17.4 0.035 13.9 0.0 6.5 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 EIE78108.1 - 0.0021 18.3 11.4 2.2 8.9 0.1 5.8 3 2 3 6 6 6 1 Tetratricopeptide repeat DUF4368 PF14287.1 EIE78108.1 - 0.061 13.1 0.1 5.8 6.7 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4368) NUFIP2 PF15293.1 EIE78108.1 - 0.081 11.6 0.1 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 2 FTH PF01827.22 EIE78108.1 - 0.083 12.4 0.1 0.63 9.6 0.0 2.1 2 0 0 2 2 2 0 FTH domain NSF PF02071.15 EIE78108.1 - 0.088 13.3 24.1 0.24 12.0 0.2 7.0 7 0 0 7 7 6 0 Aromatic-di-Alanine (AdAR) repeat TPR_14 PF13428.1 EIE78108.1 - 0.089 13.4 13.0 13 6.7 0.1 5.2 2 2 3 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 EIE78108.1 - 0.18 12.5 19.9 1.1 10.0 3.8 3.9 2 1 1 4 4 3 0 Tetratricopeptide repeat Spatacsin_C PF14649.1 EIE78108.1 - 0.26 10.1 3.8 0.39 9.5 0.3 2.3 2 1 0 2 2 2 0 Spatacsin C-terminus TPR_10 PF13374.1 EIE78108.1 - 0.52 10.3 2.9 42 4.2 0.0 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 EIE78108.1 - 0.55 10.2 29.3 2.7 8.1 0.7 7.5 5 2 3 8 8 8 0 Tetratricopeptide repeat TPR_8 PF13181.1 EIE78108.1 - 2.6 8.0 14.7 1.1e+02 2.9 0.2 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat PspA_IM30 PF04012.7 EIE78108.1 - 3 7.1 6.7 0.16 11.3 0.5 1.9 2 2 0 2 2 2 0 PspA/IM30 family TPR_19 PF14559.1 EIE78108.1 - 3.3 8.1 16.7 2.1 8.7 0.1 4.7 3 1 2 5 5 5 0 Tetratricopeptide repeat MIT PF04212.13 EIE78108.1 - 7 6.6 20.9 3.5 7.5 1.9 5.0 5 2 0 5 5 3 0 MIT (microtubule interacting and transport) domain Pkinase PF00069.20 EIE78109.1 - 3.5e-51 173.8 0.1 5e-51 173.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE78109.1 - 1.1e-19 70.5 0.0 1.5e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIE78109.1 - 0.0034 17.1 0.1 0.0049 16.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EIE78109.1 - 0.041 12.9 0.1 0.073 12.1 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EIE78109.1 - 0.11 11.8 0.3 0.28 10.4 0.0 1.7 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Nup96 PF12110.3 EIE78110.1 - 4e-17 62.2 2.4 1e-07 31.4 0.1 2.2 1 1 0 2 2 2 2 Nuclear protein 96 TP_methylase PF00590.15 EIE78111.1 - 3.1e-19 69.5 0.0 5.1e-19 68.8 0.0 1.3 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases rve PF00665.21 EIE78112.1 - 3.1e-10 40.2 0.0 5.7e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 EIE78112.1 - 4.8e-07 29.3 1.1 9.2e-07 28.4 0.8 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 EIE78112.1 - 0.0045 16.6 0.7 0.0095 15.6 0.5 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain YcgR_2 PF12945.2 EIE78112.1 - 0.026 14.3 0.0 0.058 13.2 0.0 1.6 1 0 0 1 1 1 0 Flagellar protein YcgR LAG1-DNAbind PF09271.6 EIE78113.1 - 0.019 15.4 0.8 0.041 14.3 0.5 1.5 1 0 0 1 1 1 0 LAG1, DNA binding FKBP_N PF01346.13 EIE78113.1 - 0.062 13.3 6.5 0.037 14.0 1.9 2.2 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase DUF2508 PF10704.4 EIE78113.1 - 0.24 11.6 4.0 22 5.3 1.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) YebO PF13974.1 EIE78113.1 - 0.61 9.8 8.8 9.1 6.1 0.0 2.4 2 0 0 2 2 2 0 YebO-like protein Transposase_21 PF02992.9 EIE78115.1 - 1.8e-16 59.9 0.1 2.4e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 Transposase family tnp2 DUF1258 PF06869.7 EIE78115.1 - 0.0021 17.1 0.0 0.0033 16.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) DUF4218 PF13960.1 EIE78115.1 - 0.059 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) Chromo PF00385.19 EIE78116.1 - 8.4e-12 44.5 0.6 1.9e-11 43.4 0.4 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVT_1 PF00078.22 EIE78117.1 - 4.4e-17 62.1 0.0 8.5e-17 61.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 EIE78117.1 - 0.00025 21.4 0.2 0.00056 20.3 0.2 1.6 1 0 0 1 1 1 1 Aspartyl protease UBN2_2 PF14227.1 EIE78117.1 - 0.0051 16.3 0.1 0.2 11.2 0.0 2.5 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type Asp_protease PF09668.5 EIE78117.1 - 0.036 13.6 0.1 0.099 12.2 0.1 1.7 1 1 0 1 1 1 0 Aspartyl protease UBN2 PF14223.1 EIE78117.1 - 0.045 13.5 0.2 0.18 11.6 0.0 2.0 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type gag-asp_proteas PF13975.1 EIE78117.1 - 0.1 12.4 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease HTH_Tnp_Tc3_2 PF01498.13 EIE78118.1 - 1e-16 60.7 3.5 1.3e-16 60.3 0.4 2.3 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 EIE78118.1 - 1.9e-09 37.6 0.1 5.4e-09 36.1 0.1 1.8 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EIE78118.1 - 3.9e-09 35.8 0.9 1.6e-06 27.5 0.0 2.8 3 0 0 3 3 2 1 Homeodomain-like domain DDE_3 PF13358.1 EIE78118.1 - 1.1e-07 31.6 0.2 2.3e-07 30.6 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.1 EIE78118.1 - 1.2e-07 32.3 0.2 7e-06 26.7 0.0 3.1 2 1 1 3 3 3 1 Homeodomain-like domain HTH_7 PF02796.10 EIE78118.1 - 1.1e-06 28.3 2.9 0.00023 20.9 0.1 3.2 2 1 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_11 PF08279.7 EIE78118.1 - 1.8e-06 27.4 1.8 0.00024 20.6 0.2 2.6 2 0 0 2 2 2 1 HTH domain HTH_28 PF13518.1 EIE78118.1 - 7.1e-06 25.9 0.0 0.0044 17.0 0.0 2.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_38 PF13936.1 EIE78118.1 - 1e-05 24.9 0.3 9.7e-05 21.8 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_36 PF13730.1 EIE78118.1 - 1.3e-05 25.2 2.9 0.00019 21.5 0.3 2.9 2 1 1 3 3 3 1 Helix-turn-helix domain HTH_21 PF13276.1 EIE78118.1 - 2.7e-05 24.0 0.0 0.00014 21.7 0.0 2.1 2 0 0 2 2 2 1 HTH-like domain HTH_24 PF13412.1 EIE78118.1 - 9.7e-05 21.6 0.6 0.0097 15.2 0.1 2.8 3 0 0 3 3 2 1 Winged helix-turn-helix DNA-binding HTH_33 PF13592.1 EIE78118.1 - 0.00012 21.5 0.1 0.00038 19.9 0.0 1.9 2 0 0 2 2 1 1 Winged helix-turn helix HTH_Tnp_ISL3 PF13542.1 EIE78118.1 - 0.00018 20.6 0.0 0.072 12.2 0.0 2.7 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 GerE PF00196.14 EIE78118.1 - 0.00065 18.9 0.2 0.0019 17.5 0.1 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family KorB PF08535.5 EIE78118.1 - 0.001 19.1 0.1 0.0028 17.7 0.0 1.7 1 0 0 1 1 1 1 KorB domain HTH_3 PF01381.17 EIE78118.1 - 0.0012 18.6 1.2 0.021 14.6 0.3 2.3 2 0 0 2 2 2 1 Helix-turn-helix Phage_terminase PF10668.4 EIE78118.1 - 0.0013 18.4 1.7 0.0018 17.9 0.0 2.1 2 0 0 2 2 2 1 Phage terminase small subunit GntR PF00392.16 EIE78118.1 - 0.0013 18.1 0.1 0.39 10.1 0.0 2.6 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family TrmB PF01978.14 EIE78118.1 - 0.0017 18.0 0.7 0.023 14.3 0.1 2.4 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB Sigma70_r4_2 PF08281.7 EIE78118.1 - 0.0017 17.7 0.3 0.015 14.7 0.1 2.3 2 0 0 2 2 2 1 Sigma-70, region 4 LacI PF00356.16 EIE78118.1 - 0.0021 17.6 0.5 1.1 8.9 0.1 2.5 2 0 0 2 2 2 1 Bacterial regulatory proteins, lacI family HTH_AsnC-type PF13404.1 EIE78118.1 - 0.0021 17.5 0.1 0.0061 16.0 0.0 1.7 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain HTH_10 PF04967.7 EIE78118.1 - 0.0086 15.6 0.1 0.3 10.7 0.0 2.3 2 0 0 2 2 2 1 HTH DNA binding domain HTH_5 PF01022.15 EIE78118.1 - 0.0089 15.6 0.0 0.15 11.7 0.0 2.4 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family HTH_Tnp_1_2 PF13022.1 EIE78118.1 - 0.011 15.5 0.1 0.28 10.9 0.0 2.6 3 0 0 3 3 3 0 Helix-turn-helix of insertion element transposase Trp_repressor PF01371.14 EIE78118.1 - 0.012 15.5 0.6 0.051 13.4 0.2 2.0 2 0 0 2 2 2 0 Trp repressor protein CENP-B_N PF04218.8 EIE78118.1 - 0.017 14.5 0.1 0.48 9.8 0.1 2.4 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain HTH_17 PF12728.2 EIE78118.1 - 0.021 15.0 0.1 1.1 9.6 0.0 3.0 3 0 0 3 3 2 0 Helix-turn-helix domain HTH_IclR PF09339.5 EIE78118.1 - 0.021 14.4 0.1 0.15 11.6 0.0 2.4 3 0 0 3 3 2 0 IclR helix-turn-helix domain HTH_6 PF01418.12 EIE78118.1 - 0.028 14.1 0.8 2.4 7.9 0.1 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family Sigma54_DBD PF04552.8 EIE78118.1 - 0.044 13.3 1.9 0.24 10.9 0.1 2.6 3 0 0 3 3 2 0 Sigma-54, DNA binding domain Fe_dep_repress PF01325.14 EIE78118.1 - 0.32 10.9 1.4 2.6 8.0 0.1 2.7 3 0 0 3 3 3 0 Iron dependent repressor, N-terminal DNA binding domain FXa_inhibition PF14670.1 EIE78119.1 - 0.55 10.3 3.9 1.3 9.2 0.3 2.3 2 0 0 2 2 2 0 Coagulation Factor Xa inhibitory site DDE_3 PF13358.1 EIE78120.1 - 7.1e-18 64.7 0.1 1.7e-17 63.5 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE78120.1 - 5.4e-12 45.5 1.0 5.4e-12 45.5 0.7 2.2 3 0 0 3 3 3 1 Transposase HTH_29 PF13551.1 EIE78120.1 - 0.0002 21.4 0.7 0.0004 20.5 0.1 1.8 2 0 0 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.1 EIE78120.1 - 0.00095 18.7 0.1 0.0025 17.3 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_7 PF02796.10 EIE78120.1 - 0.008 16.0 0.0 0.021 14.6 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_30 PF13556.1 EIE78120.1 - 0.022 14.3 0.0 0.17 11.4 0.0 2.1 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain HTH_38 PF13936.1 EIE78120.1 - 0.029 13.9 0.0 0.11 12.0 0.0 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain RecX PF02631.11 EIE78120.1 - 0.13 12.4 0.3 0.27 11.4 0.2 1.5 1 0 0 1 1 1 0 RecX family DUF1203 PF06718.6 EIE78123.1 - 0.085 12.6 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1203) Transposase_21 PF02992.9 EIE78124.1 - 6.6e-22 77.7 0.1 1e-21 77.0 0.1 1.3 1 0 0 1 1 1 1 Transposase family tnp2 USP7_ICP0_bdg PF12436.3 EIE78126.1 - 0.12 11.6 0.0 0.12 11.5 0.0 1.0 1 0 0 1 1 1 0 ICP0-binding domain of Ubiquitin-specific protease 7 DUF1759 PF03564.10 EIE78128.1 - 8.2e-05 22.4 0.4 9.3e-05 22.2 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) rve PF00665.21 EIE78129.1 - 1.8e-20 73.2 0.0 5.1e-20 71.7 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE78129.1 - 1e-10 41.3 0.2 2.3e-10 40.1 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE78129.1 - 1.3e-08 34.3 0.3 3.4e-08 33.0 0.2 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.12 EIE78130.1 - 0.00068 19.6 0.8 0.0016 18.4 0.1 2.0 2 0 0 2 2 2 1 Retrotransposon gag protein NurA PF09376.5 EIE78131.1 - 0.035 13.5 0.4 0.041 13.3 0.3 1.2 1 0 0 1 1 1 0 NurA domain DUF4119 PF13494.1 EIE78131.1 - 0.095 12.6 2.5 0.16 11.9 0.8 2.0 1 1 1 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF4119) PRKCSH PF07915.8 EIE78131.1 - 6.6 7.6 8.9 0.57 11.0 0.8 2.4 1 1 1 2 2 2 0 Glucosidase II beta subunit-like protein Asp_protease PF09668.5 EIE78132.1 - 3.3e-10 39.5 0.0 5.4e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 EIE78132.1 - 5.4e-08 33.2 0.0 1.5e-07 31.7 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 EIE78132.1 - 3.5e-06 26.8 0.3 1.9e-05 24.4 0.0 2.4 2 1 1 3 3 3 1 Retroviral aspartyl protease RVP_2 PF08284.6 EIE78132.1 - 5.6e-06 26.3 0.0 1.4e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EIE78132.1 - 0.00033 20.4 0.1 0.00062 19.5 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease NOA36 PF06524.7 EIE78132.1 - 2.6 7.2 7.0 5.2 6.2 4.8 1.4 1 0 0 1 1 1 0 NOA36 protein DDE_Tnp_IS1595 PF12762.2 EIE78133.1 - 2.9e-06 27.2 0.1 5e-06 26.4 0.1 1.4 1 0 0 1 1 1 1 ISXO2-like transposase domain RVT_1 PF00078.22 EIE78134.1 - 1e-15 57.7 0.0 1.9e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Spuma_A9PTase PF03539.9 EIE78134.1 - 0.0034 17.3 0.4 0.012 15.5 0.0 1.9 1 1 1 2 2 2 1 Spumavirus aspartic protease (A9) DDE_3 PF13358.1 EIE78135.1 - 1.3e-12 47.6 0.1 3.1e-12 46.4 0.1 1.7 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE78135.1 - 2.1e-08 34.0 0.7 6.1e-08 32.6 0.6 1.8 2 1 0 2 2 2 1 Transposase zf-H2C2 PF09337.5 EIE78136.1 - 0.00092 18.5 0.3 0.002 17.5 0.1 1.7 1 1 0 1 1 1 1 His(2)-Cys(2) zinc finger zf-3CxxC PF13695.1 EIE78136.1 - 0.12 12.5 0.6 0.18 12.0 0.1 1.6 2 1 0 2 2 2 0 Zinc-binding domain zf-RVT PF13966.1 EIE78139.1 - 1.7e-05 25.0 1.6 5.1e-05 23.4 1.1 1.9 1 1 0 1 1 1 1 zinc-binding in reverse transcriptase DDE_3 PF13358.1 EIE78140.1 - 1.2e-21 77.0 0.2 1.9e-21 76.3 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE78140.1 - 2e-15 56.6 0.4 9.2e-15 54.4 0.2 2.1 2 0 0 2 2 2 1 Transposase rve PF00665.21 EIE78140.1 - 0.0032 17.5 0.0 0.0074 16.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Ku_PK_bind PF08785.6 EIE78140.1 - 0.009 15.9 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 Ku C terminal domain like HTH_29 PF13551.1 EIE78140.1 - 0.031 14.4 0.1 0.13 12.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.13 EIE78141.1 - 8.9e-14 51.3 0.4 2.4e-13 49.9 0.3 1.8 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.1 EIE78141.1 - 1.2e-05 25.3 0.6 2.1e-05 24.6 0.4 1.4 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EIE78141.1 - 0.00028 20.4 0.7 0.0026 17.3 0.0 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_7 PF02796.10 EIE78141.1 - 0.00093 19.0 0.5 0.045 13.6 0.1 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase DUF2110 PF09883.4 EIE78141.1 - 0.0091 15.6 0.3 0.28 10.7 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2110) DDE_3 PF13358.1 EIE78142.1 - 1.4e-07 31.3 1.0 2.3e-07 30.6 0.4 1.6 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_23 PF13384.1 EIE78143.1 - 0.00086 18.8 0.0 0.0014 18.2 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_7 PF02796.10 EIE78143.1 - 0.0065 16.3 0.2 0.02 14.7 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase GcrA PF07750.6 EIE78143.1 - 0.037 14.2 0.0 0.037 14.2 0.0 1.2 1 0 0 1 1 1 0 GcrA cell cycle regulator HTH_Tnp_Tc3_2 PF01498.13 EIE78143.1 - 0.078 13.0 3.2 0.45 10.6 0.1 2.9 2 2 1 3 3 3 0 Transposase HTH_36 PF13730.1 EIE78143.1 - 0.093 12.8 0.2 9 6.5 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain rve PF00665.21 EIE78145.1 - 8.7e-18 64.5 0.0 3.7e-17 62.5 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 EIE78145.1 - 3.9e-14 52.5 0.9 1e-13 51.1 0.6 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE78145.1 - 1.4e-06 27.8 1.3 5.6e-06 25.9 0.7 2.2 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.1 EIE78145.1 - 4.8e-05 23.7 0.1 0.00046 20.6 0.0 2.4 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.15 EIE78145.1 - 0.00057 19.7 0.1 0.0021 17.9 0.0 2.0 1 0 0 1 1 1 1 Retroviral aspartyl protease Tudor-knot PF11717.3 EIE78145.1 - 0.019 14.6 0.7 0.054 13.2 0.5 1.8 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain YcgR_2 PF12945.2 EIE78145.1 - 0.028 14.2 0.0 0.42 10.5 0.0 2.5 2 0 0 2 2 2 0 Flagellar protein YcgR gag-asp_proteas PF13975.1 EIE78145.1 - 0.07 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease HTH_Tnp_Tc3_2 PF01498.13 EIE78146.1 - 1.2e-06 28.4 3.5 1.7e-06 28.0 0.2 2.5 2 1 1 3 3 3 1 Transposase HTH_23 PF13384.1 EIE78146.1 - 0.023 14.3 0.0 0.041 13.5 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain GcrA PF07750.6 EIE78146.1 - 0.024 14.8 0.1 0.031 14.4 0.1 1.5 1 1 0 1 1 1 0 GcrA cell cycle regulator HTH_7 PF02796.10 EIE78146.1 - 0.032 14.1 0.3 0.075 12.9 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase rve PF00665.21 EIE78147.1 - 7.1e-18 64.8 0.0 3.2e-17 62.7 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 EIE78147.1 - 2.9e-14 52.9 0.9 8.1e-14 51.4 0.6 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 EIE78147.1 - 3.8e-05 24.1 0.1 0.0004 20.8 0.0 2.4 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.15 EIE78147.1 - 0.00048 19.9 0.1 0.0018 18.1 0.0 2.0 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EIE78147.1 - 0.06 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease YcgR_2 PF12945.2 EIE78147.1 - 0.064 13.1 0.0 1 9.2 0.0 2.5 2 0 0 2 2 2 0 Flagellar protein YcgR LysM PF01476.15 EIE78149.1 - 3.1e-09 36.5 0.2 2.6e-05 23.9 0.0 2.4 2 0 0 2 2 2 2 LysM domain HTH_28 PF13518.1 EIE78149.1 - 0.0013 18.7 0.1 0.43 10.6 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain Pex14_N PF04695.8 EIE78149.1 - 0.067 13.2 9.3 0.12 12.3 6.5 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region IFT43 PF15305.1 EIE78149.1 - 0.094 12.7 4.0 0.15 12.0 2.8 1.2 1 0 0 1 1 1 0 Intraflagellar transport protein 43 DUF913 PF06025.7 EIE78149.1 - 0.35 9.5 6.6 0.48 9.1 4.6 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF3807 PF12720.2 EIE78149.1 - 0.47 10.6 12.3 0.68 10.0 8.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Mucin PF01456.12 EIE78149.1 - 0.94 9.2 15.0 1.5 8.5 10.4 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF2413 PF10310.4 EIE78149.1 - 1.1 8.0 14.1 1.3 7.7 9.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Dicty_REP PF05086.7 EIE78149.1 - 4.5 4.8 11.2 5.5 4.6 7.8 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Sec10 PF07393.6 EIE78149.1 - 6 4.9 10.8 7.4 4.6 7.5 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec10 RPOL_N PF14700.1 EIE78149.1 - 6.8 5.8 10.3 9.3 5.3 7.1 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal Sec5 PF15469.1 EIE78151.1 - 4.7e-16 59.0 7.5 4.7e-16 59.0 5.2 2.3 2 1 1 3 3 3 1 Exocyst complex component Sec5 DUF2120 PF09893.4 EIE78151.1 - 0.075 12.9 5.4 0.97 9.3 0.1 3.9 4 0 0 4 4 4 0 Uncharacterized protein conserved in archaea (DUF2120) Glyco_hydro_15 PF00723.16 EIE78152.1 - 1.2e-125 419.5 0.0 1.7e-125 419.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 GPI-anchored PF10342.4 EIE78153.1 - 0.23 11.9 15.0 1 9.9 1.6 2.7 2 1 0 2 2 2 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Post_transc_reg PF13797.1 EIE78155.1 - 0.023 14.2 1.8 0.53 9.9 0.0 2.7 2 0 0 2 2 2 0 Post-transcriptional regulator DUF3020 PF11223.3 EIE78156.1 - 2e-17 63.3 10.1 2e-17 63.3 7.0 3.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3020) Chorion_2 PF03964.10 EIE78156.1 - 0.0087 16.5 3.3 0.0087 16.5 2.3 2.6 3 1 1 4 4 4 1 Chorion family 2 Cyclin_C PF02984.14 EIE78156.1 - 0.38 10.7 4.2 0.13 12.1 0.4 2.1 2 0 0 2 2 2 0 Cyclin, C-terminal domain BAR PF03114.13 EIE78157.1 - 3.7e-30 105.1 8.0 5e-30 104.7 5.6 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 EIE78157.1 - 2.5e-17 61.9 0.3 6.4e-17 60.6 0.1 1.9 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EIE78157.1 - 3.5e-17 61.7 0.2 6.6e-17 60.8 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EIE78157.1 - 2.1e-11 43.1 0.0 3.7e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain BAR_2 PF10455.4 EIE78157.1 - 2.9e-08 33.0 3.1 4.3e-08 32.4 2.1 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking Tropomyosin PF00261.15 EIE78157.1 - 0.061 12.4 11.3 0.099 11.7 7.8 1.3 1 0 0 1 1 1 0 Tropomyosin CDC24 PF06395.6 EIE78157.1 - 0.086 12.9 0.1 2.4 8.2 0.1 2.2 2 0 0 2 2 2 0 CDC24 Calponin APG6 PF04111.7 EIE78157.1 - 0.16 10.9 12.6 0.23 10.4 8.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 SR-25 PF10500.4 EIE78158.1 - 0.00083 18.8 6.3 0.0011 18.4 4.4 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein HOOK PF05622.7 EIE78158.1 - 0.0022 15.9 0.5 0.0027 15.6 0.4 1.0 1 0 0 1 1 1 1 HOOK protein DUF4600 PF15372.1 EIE78158.1 - 0.04 14.1 2.0 0.057 13.6 0.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4600) FlxA PF14282.1 EIE78158.1 - 0.31 10.9 9.0 0.66 9.9 6.2 1.6 1 0 0 1 1 1 0 FlxA-like protein DUF3446 PF11928.3 EIE78158.1 - 5 7.3 13.0 0.34 11.1 4.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) Pkinase PF00069.20 EIE78159.1 - 2.3e-10 40.0 0.0 3.1e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE78159.1 - 0.00024 20.2 0.0 0.00034 19.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE78159.1 - 0.026 13.4 0.0 0.033 13.1 0.0 1.1 1 0 0 1 1 1 0 Kinase-like UcrQ PF02939.11 EIE78160.1 - 7.3e-29 99.4 0.2 8.2e-29 99.2 0.1 1.0 1 0 0 1 1 1 1 UcrQ family PAPS_reduct PF01507.14 EIE78161.1 - 8.5e-44 149.4 0.0 1.1e-43 149.0 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Ras PF00071.17 EIE78162.1 - 2.2e-59 199.4 0.5 2.7e-59 199.2 0.3 1.1 1 0 0 1 1 1 1 Ras family Arf PF00025.16 EIE78162.1 - 8.4e-18 64.2 0.2 1e-17 63.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 EIE78162.1 - 3.1e-17 63.1 0.3 7.2e-17 61.9 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 EIE78162.1 - 4.3e-09 36.3 0.1 9.3e-09 35.2 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EIE78162.1 - 1.3e-07 31.2 0.1 4.9e-07 29.3 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EIE78162.1 - 1.9e-07 30.4 0.1 2.3e-07 30.1 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EIE78162.1 - 6e-06 25.5 0.2 0.0003 20.0 0.0 2.1 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 EIE78162.1 - 0.00098 18.4 0.0 0.02 14.2 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_22 PF13401.1 EIE78162.1 - 0.018 15.1 0.0 1.1 9.4 0.0 2.2 1 1 0 2 2 2 0 AAA domain Aminotran_3 PF00202.16 EIE78162.1 - 0.022 13.6 0.0 0.026 13.3 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-III DUF258 PF03193.11 EIE78162.1 - 0.023 13.8 0.1 0.092 11.9 0.0 2.0 2 1 0 2 2 2 0 Protein of unknown function, DUF258 Glyco_tran_WbsX PF14307.1 EIE78162.1 - 0.034 13.3 0.2 0.041 13.0 0.1 1.1 1 0 0 1 1 1 0 Glycosyltransferase WbsX Gti1_Pac2 PF09729.4 EIE78163.1 - 3.2e-55 186.5 0.8 3.2e-55 186.5 0.5 2.1 2 1 0 2 2 2 1 Gti1/Pac2 family DUF1548 PF07579.6 EIE78163.1 - 0.026 14.6 0.2 0.056 13.5 0.1 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1548) Melibiase PF02065.13 EIE78164.1 - 5.9e-112 374.2 0.0 8.4e-112 373.7 0.0 1.1 1 0 0 1 1 1 1 Melibiase DUF187 PF02638.10 EIE78164.1 - 8e-08 31.5 0.0 1.3e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase like GH101 Glyco_hydro_31 PF01055.21 EIE78164.1 - 3.3e-06 26.2 0.0 4.4e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Glyco_hydro_97 PF10566.4 EIE78164.1 - 0.00094 18.3 0.0 0.0016 17.6 0.0 1.2 1 0 0 1 1 1 1 Glycoside hydrolase 97 GHL6 PF14871.1 EIE78164.1 - 0.14 12.1 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 ATP_bind_4 PF01902.12 EIE78164.1 - 0.15 11.4 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 ATP-binding region Crystall PF00030.14 EIE78165.1 - 0.027 14.3 3.8 1 9.2 0.1 3.2 3 0 0 3 3 3 0 Beta/Gamma crystallin Syja_N PF02383.13 EIE78166.1 - 4.7e-55 186.6 0.9 3.1e-48 164.1 0.1 2.0 1 1 1 2 2 2 2 SacI homology domain 14-3-3 PF00244.15 EIE78167.1 - 3.9e-114 379.6 5.3 4.5e-114 379.4 3.7 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF327 PF03885.8 EIE78167.1 - 0.15 11.9 2.1 0.38 10.5 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF327) TPR_12 PF13424.1 EIE78167.1 - 0.26 11.2 2.4 4.6 7.2 0.2 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat PP2C PF00481.16 EIE78168.1 - 1.1e-52 179.0 0.0 1.6e-52 178.4 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.2 EIE78168.1 - 1.9e-46 154.9 69.4 7.7e-07 28.6 0.9 13.2 7 5 6 13 13 13 11 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EIE78168.1 - 1.3e-36 124.0 59.9 1.3e-07 31.2 1.2 9.1 2 2 6 11 11 11 10 Leucine rich repeat Guanylate_cyc PF00211.15 EIE78168.1 - 2.5e-30 105.2 0.0 4.7e-30 104.3 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.28 EIE78168.1 - 1.1e-25 85.7 71.0 0.043 13.8 0.2 20.5 19 1 0 19 19 19 10 Leucine Rich Repeat LRR_7 PF13504.1 EIE78168.1 - 1.7e-10 39.2 61.8 4.8 7.8 0.0 18.4 20 0 0 20 20 20 6 Leucine rich repeat RA PF00788.18 EIE78168.1 - 2.2e-10 40.8 0.0 5.2e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain PP2C_2 PF13672.1 EIE78168.1 - 0.0044 16.4 0.0 0.0082 15.5 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PALP PF00291.20 EIE78169.1 - 1.9e-43 148.8 0.0 2.5e-43 148.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Ribosomal_S9 PF00380.14 EIE78170.1 - 2.8e-35 121.1 0.2 3.2e-35 121.0 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 4HBT PF03061.17 EIE78173.1 - 0.037 14.1 0.2 1.1 9.4 0.0 2.6 2 1 0 2 2 2 0 Thioesterase superfamily Nucleotid_trans PF03407.11 EIE78174.1 - 0.081 12.6 0.0 0.15 11.7 0.0 1.5 1 1 0 1 1 1 0 Nucleotide-diphospho-sugar transferase Peptidase_S8 PF00082.17 EIE78176.1 - 6.2e-46 156.7 14.2 9.4e-46 156.2 9.8 1.2 1 0 0 1 1 1 1 Subtilase family DUF1811 PF08838.5 EIE78176.1 - 0.091 12.7 0.0 0.33 10.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1811) CD20 PF04103.10 EIE78176.1 - 0.12 12.3 3.9 0.42 10.5 0.1 2.5 2 0 0 2 2 2 0 CD20-like family FAT PF02259.18 EIE78177.1 - 3.3e-74 249.9 9.7 1e-73 248.3 6.7 1.9 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 EIE78177.1 - 3.3e-22 79.0 0.7 1.2e-21 77.2 0.3 2.2 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 EIE78177.1 - 2.2e-06 27.0 0.7 6.4e-06 25.4 0.5 1.9 1 0 0 1 1 1 1 FATC domain 2OG-FeII_Oxy_2 PF13532.1 EIE78178.1 - 1.3e-05 25.0 0.0 1.6e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EIE78178.1 - 0.0019 18.4 0.0 0.0023 18.2 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Botulinum_HA-17 PF05588.6 EIE78179.1 - 0.095 12.5 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Clostridium botulinum HA-17 protein CBS PF00571.23 EIE78180.1 - 7.2e-10 38.5 0.0 2.9e-05 23.7 0.0 2.7 3 0 0 3 3 3 2 CBS domain HTH_9 PF08221.6 EIE78180.1 - 0.048 13.5 0.3 2.2 8.2 0.0 3.2 4 0 0 4 4 4 0 RNA polymerase III subunit RPC82 helix-turn-helix domain ALS_ss_C PF10369.4 EIE78181.1 - 7.3e-20 70.4 0.0 1.9e-17 62.7 0.0 2.4 2 0 0 2 2 2 2 Small subunit of acetolactate synthase ACT PF01842.20 EIE78181.1 - 2.1e-12 46.2 0.1 3.7e-12 45.4 0.1 1.4 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.1 EIE78181.1 - 6e-10 38.7 0.0 1.1e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 ACT domain RasGEF PF00617.14 EIE78182.1 - 7.8e-08 32.2 0.1 9.9e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 RasGEF domain GPI-anchored PF10342.4 EIE78183.1 - 4.7e-08 33.4 0.2 1.1e-07 32.2 0.2 1.6 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Pkinase PF00069.20 EIE78184.1 - 3.4e-66 223.0 0.0 4.3e-66 222.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE78184.1 - 3.4e-42 144.2 0.0 4.9e-42 143.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE78184.1 - 3.3e-08 32.8 0.0 9.9e-08 31.2 0.0 1.8 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.17 EIE78184.1 - 0.0016 17.7 0.0 0.0033 16.7 0.0 1.5 1 1 0 1 1 1 1 RIO1 family Kdo PF06293.9 EIE78184.1 - 0.0042 16.1 0.0 0.0077 15.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIE78184.1 - 0.022 14.4 0.0 0.063 13.0 0.0 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family Beta-Casp PF10996.3 EIE78185.1 - 2e-28 98.8 0.0 7.5e-28 96.9 0.0 2.0 2 0 0 2 2 2 1 Beta-Casp domain RMMBL PF07521.7 EIE78185.1 - 3.2e-14 52.4 0.0 7.2e-14 51.3 0.0 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_2 PF12706.2 EIE78185.1 - 6.8e-12 45.3 0.6 1.2e-09 38.0 0.2 2.5 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EIE78185.1 - 8e-11 41.9 0.3 1.8e-10 40.8 0.2 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.1 EIE78185.1 - 0.0037 16.9 0.2 0.025 14.3 0.0 2.3 3 1 0 3 3 3 1 Beta-lactamase superfamily domain VHS PF00790.14 EIE78186.1 - 4.5e-38 130.0 2.6 3.8e-31 107.6 0.0 3.3 3 0 0 3 3 3 2 VHS domain GAT PF03127.9 EIE78186.1 - 3.7e-11 42.8 8.5 6.1e-11 42.1 4.0 2.4 2 0 0 2 2 2 1 GAT domain Alpha_adaptinC2 PF02883.15 EIE78186.1 - 0.00012 22.4 0.2 0.00028 21.1 0.2 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain CutA1 PF03091.10 EIE78186.1 - 0.061 12.9 0.3 0.13 11.8 0.2 1.6 1 0 0 1 1 1 0 CutA1 divalent ion tolerance protein ISG65-75 PF11727.3 EIE78186.1 - 0.3 10.0 6.2 0.62 9.0 4.3 1.5 1 0 0 1 1 1 0 Invariant surface glycoprotein DUF2407_C PF13373.1 EIE78187.1 - 3e-22 79.0 9.3 3.3e-20 72.4 6.4 2.1 1 1 0 1 1 1 1 DUF2407 C-terminal domain MtrB PF05440.7 EIE78187.1 - 0.014 15.4 0.1 0.18 11.8 0.0 2.1 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B ATP_synt_I PF03899.10 EIE78187.1 - 0.017 15.2 0.8 0.026 14.6 0.6 1.3 1 0 0 1 1 1 0 ATP synthase I chain Halogen_Hydrol PF10112.4 EIE78187.1 - 0.055 12.8 5.9 0.34 10.2 0.0 2.0 1 1 1 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Acetyltransf_11 PF13720.1 EIE78187.1 - 0.14 12.3 0.0 0.2 11.9 0.0 1.2 1 0 0 1 1 1 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 DUF4131 PF13567.1 EIE78187.1 - 0.26 10.6 1.6 0.37 10.1 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) MCM PF00493.18 EIE78189.1 - 2.2e-141 470.4 0.2 3e-141 470.0 0.1 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 EIE78189.1 - 3e-21 76.0 20.2 3e-21 76.0 14.0 2.4 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 EIE78189.1 - 1.1e-19 71.0 0.3 3.1e-19 69.6 0.2 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EIE78189.1 - 1.6e-08 33.9 0.1 2.1e-06 27.0 0.0 2.6 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EIE78189.1 - 1e-05 25.1 0.0 0.0013 18.3 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EIE78189.1 - 3.3e-05 23.6 0.0 8.6e-05 22.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 EIE78189.1 - 0.027 13.9 0.1 0.29 10.6 0.1 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain Methyltransf_31 PF13847.1 EIE78190.1 - 6.1e-17 61.6 0.0 5.8e-16 58.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIE78190.1 - 1.2e-16 60.8 0.0 2.7e-16 59.6 0.0 1.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIE78190.1 - 1.8e-16 60.4 0.0 2.5e-15 56.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIE78190.1 - 1e-14 54.7 0.0 3.5e-14 53.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIE78190.1 - 1.8e-14 54.2 0.0 1.4e-13 51.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIE78190.1 - 7.4e-10 39.1 0.0 1.2e-09 38.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EIE78190.1 - 2.3e-09 36.8 0.0 3.6e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain RrnaAD PF00398.15 EIE78190.1 - 5e-08 32.3 0.0 7e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_9 PF08003.6 EIE78190.1 - 2.4e-07 29.7 0.0 3.4e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_26 PF13659.1 EIE78190.1 - 1e-05 25.4 0.0 2.5e-05 24.2 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain NodS PF05401.6 EIE78190.1 - 2e-05 24.0 0.0 3.4e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) PCMT PF01135.14 EIE78190.1 - 4.5e-05 23.0 0.0 6.6e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.8 EIE78190.1 - 0.00011 21.5 0.0 0.00019 20.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TPMT PF05724.6 EIE78190.1 - 0.0004 19.9 0.0 0.0017 17.8 0.0 2.0 2 1 0 2 2 2 1 Thiopurine S-methyltransferase (TPMT) DREV PF05219.7 EIE78190.1 - 0.00045 19.1 0.0 0.0007 18.5 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_32 PF13679.1 EIE78190.1 - 0.00061 19.4 0.0 0.00096 18.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 EIE78190.1 - 0.00073 18.9 0.0 0.0011 18.3 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Ubie_methyltran PF01209.13 EIE78190.1 - 0.01 14.9 0.0 0.045 12.8 0.0 1.9 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family CMAS PF02353.15 EIE78190.1 - 0.016 14.3 0.0 0.022 13.8 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase TehB PF03848.9 EIE78190.1 - 0.11 11.6 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB Chitin_synth_2 PF03142.10 EIE78191.1 - 1.8e-276 917.6 0.9 2.5e-276 917.2 0.6 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 EIE78191.1 - 2.2e-17 63.3 1.3 2.2e-17 63.3 0.9 2.7 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EIE78191.1 - 2.4e-17 63.4 0.0 1.5e-15 57.5 0.0 2.3 1 1 0 2 2 2 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 EIE78191.1 - 3.4e-09 36.3 0.0 6e-07 29.1 0.0 2.5 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glycos_transf_2 PF00535.21 EIE78191.1 - 0.00049 19.8 0.0 0.13 11.9 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EIE78191.1 - 0.0015 17.8 0.0 0.23 10.7 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 21 PapD-like PF14874.1 EIE78193.1 - 6e-07 29.3 0.1 0.45 10.4 0.0 5.1 5 0 0 5 5 5 2 Flagellar-associated PapD-like DUF1090 PF06476.7 EIE78193.1 - 0.18 11.4 5.1 0.46 10.1 3.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1090) Aminotran_5 PF00266.14 EIE78194.1 - 9.8e-53 179.1 0.1 1.5e-51 175.2 0.0 2.2 1 1 1 2 2 2 2 Aminotransferase class-V Tctex-1 PF03645.8 EIE78194.1 - 0.047 13.5 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Tctex-1 family Solute_trans_a PF03619.11 EIE78195.1 - 3.7e-30 105.1 8.1 6.2e-30 104.4 5.6 1.3 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Dus PF01207.12 EIE78196.1 - 1.7e-57 194.6 0.3 2.8e-57 193.9 0.2 1.4 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) FmrO PF07091.6 EIE78196.1 - 0.0076 15.2 0.7 2.2 7.1 0.1 2.3 1 1 1 2 2 2 2 Ribosomal RNA methyltransferase (FmrO) FMN_dh PF01070.13 EIE78196.1 - 0.0093 14.8 0.1 1.7 7.3 0.0 2.4 1 1 1 2 2 2 2 FMN-dependent dehydrogenase NMO PF03060.10 EIE78196.1 - 0.048 12.8 0.1 0.38 9.8 0.0 2.0 1 1 0 1 1 1 0 Nitronate monooxygenase Zn_clus PF00172.13 EIE78197.1 - 1.8e-09 37.3 11.4 3e-09 36.6 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EIE78197.1 - 5.8e-07 28.6 0.2 9.5e-07 27.9 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain FYVE PF01363.16 EIE78198.1 - 0.026 14.3 24.1 0.77 9.6 12.9 3.6 2 1 0 2 2 2 0 FYVE zinc finger RhoGAP PF00620.22 EIE78199.1 - 1.4e-35 122.1 0.1 2.5e-35 121.3 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain RhoGEF PF00621.15 EIE78200.1 - 6.2e-12 45.7 1.5 3.7e-06 26.9 0.3 2.5 1 1 1 2 2 2 2 RhoGEF domain PH PF00169.24 EIE78200.1 - 0.016 15.4 1.2 0.038 14.1 0.2 2.2 2 1 0 2 2 2 0 PH domain RGS PF00615.14 EIE78202.1 - 7.3e-19 68.0 2.1 7.3e-19 68.0 1.5 2.4 3 0 0 3 3 3 1 Regulator of G protein signaling domain RGS-like PF09128.6 EIE78202.1 - 1.4e-06 27.9 0.8 2.7e-06 27.0 0.5 1.5 1 1 0 1 1 1 1 Regulator of G protein signalling-like domain Arrestin_N PF00339.24 EIE78203.1 - 6.6e-09 35.7 0.0 5.8e-08 32.6 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EIE78203.1 - 3.2e-08 33.7 0.7 4.1e-06 26.9 0.1 2.6 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.2 EIE78203.1 - 7.1e-05 22.3 0.1 0.0003 20.3 0.0 2.0 2 0 0 2 2 2 1 Arrestin_N terminal like TPR_11 PF13414.1 EIE78204.1 - 2.3e-12 46.3 0.6 1e-08 34.6 0.0 2.4 2 0 0 2 2 2 2 TPR repeat F-box-like PF12937.2 EIE78204.1 - 4.9e-09 35.7 0.1 1.9e-08 33.8 0.1 2.1 2 0 0 2 2 2 1 F-box-like TPR_1 PF00515.23 EIE78204.1 - 6.1e-09 35.1 4.1 0.12 12.0 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 EIE78204.1 - 2.2e-07 31.3 3.0 0.0013 19.3 0.8 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 EIE78204.1 - 3.5e-07 29.6 3.6 0.56 10.2 0.2 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat F-box PF00646.28 EIE78204.1 - 1.5e-05 24.5 0.0 4.9e-05 22.8 0.0 1.9 1 0 0 1 1 1 1 F-box domain TPR_9 PF13371.1 EIE78204.1 - 0.0048 16.7 3.6 0.061 13.1 0.2 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat PRANC PF09372.5 EIE78204.1 - 0.023 14.6 0.0 0.067 13.1 0.0 1.8 1 0 0 1 1 1 0 PRANC domain TPR_12 PF13424.1 EIE78204.1 - 0.027 14.4 3.3 0.3 11.0 0.2 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 EIE78204.1 - 0.027 14.7 1.7 6.3 7.2 0.4 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2540 PF10802.3 EIE78204.1 - 0.064 12.9 0.0 2.4 7.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2540) Apc3 PF12895.2 EIE78204.1 - 0.073 13.2 0.9 0.71 10.0 0.3 2.4 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EIE78204.1 - 0.11 13.1 2.2 8.7 7.2 0.1 3.4 1 1 2 3 3 3 0 Tetratricopeptide repeat LRR_4 PF12799.2 EIE78204.1 - 0.8 9.4 14.8 3.3 7.4 0.0 5.8 4 1 1 6 6 6 0 Leucine Rich repeats (2 copies) LRR_2 PF07723.8 EIE78204.1 - 0.86 10.2 7.0 1.8 9.1 0.1 4.3 5 0 0 5 5 4 0 Leucine Rich Repeat LRR_8 PF13855.1 EIE78204.1 - 1.6 8.5 17.3 2.5 7.9 1.8 5.3 3 2 3 6 6 6 0 Leucine rich repeat HSF_DNA-bind PF00447.12 EIE78205.1 - 3.2e-35 120.4 1.7 3.2e-35 120.4 1.2 1.8 2 0 0 2 2 2 1 HSF-type DNA-binding Tmemb_cc2 PF10267.4 EIE78205.1 - 0.00032 19.4 0.2 0.00038 19.1 0.2 1.1 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein CENP-Q PF13094.1 EIE78205.1 - 0.0018 18.3 0.7 0.0029 17.6 0.5 1.3 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit SseC PF04888.7 EIE78205.1 - 0.0025 17.1 1.1 0.003 16.9 0.8 1.1 1 0 0 1 1 1 1 Secretion system effector C (SseC) like family Transposase_22 PF02994.9 EIE78205.1 - 0.003 16.1 1.7 0.0039 15.7 0.8 1.5 2 0 0 2 2 2 1 L1 transposable element Prefoldin_2 PF01920.15 EIE78205.1 - 0.0092 15.7 3.3 0.013 15.2 1.9 1.6 1 1 0 1 1 1 1 Prefoldin subunit APG6 PF04111.7 EIE78205.1 - 0.031 13.3 1.6 0.04 12.9 1.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Seryl_tRNA_N PF02403.17 EIE78205.1 - 0.031 14.2 2.4 0.063 13.2 1.7 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain ATG16 PF08614.6 EIE78205.1 - 0.035 13.9 2.1 0.049 13.4 1.5 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF3450 PF11932.3 EIE78205.1 - 0.046 12.9 0.9 0.068 12.4 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF3829 PF12889.2 EIE78205.1 - 0.066 12.3 3.5 0.059 12.5 1.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3829) Cortex-I_coil PF09304.5 EIE78205.1 - 0.074 13.0 1.6 0.11 12.5 1.1 1.3 1 0 0 1 1 1 0 Cortexillin I, coiled coil CCDC-167 PF15188.1 EIE78205.1 - 0.098 12.6 0.1 0.21 11.5 0.1 1.7 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Nsp1_C PF05064.8 EIE78205.1 - 0.099 12.2 1.1 0.2 11.2 0.8 1.5 1 0 0 1 1 1 0 Nsp1-like C-terminal region TMPIT PF07851.8 EIE78205.1 - 0.3 10.0 3.1 0.45 9.5 2.2 1.2 1 0 0 1 1 1 0 TMPIT-like protein IncA PF04156.9 EIE78205.1 - 0.36 10.4 3.1 0.33 10.5 1.1 1.5 1 1 0 2 2 2 0 IncA protein DMPK_coil PF08826.5 EIE78205.1 - 2.4 8.1 5.2 0.9 9.4 1.4 1.9 2 0 0 2 2 2 0 DMPK coiled coil domain like HTH_18 PF12833.2 EIE78206.1 - 0.14 12.2 0.1 0.19 11.8 0.1 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain Glyco_hydro_28 PF00295.12 EIE78207.1 - 1.1e-60 205.2 27.2 3.2e-60 203.8 18.9 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Sulfotransfer_3 PF13469.1 EIE78208.1 - 2.2e-05 25.4 0.0 4.3e-05 24.5 0.0 1.5 1 1 0 1 1 1 1 Sulfotransferase family Ribonuc_2-5A PF06479.7 EIE78208.1 - 0.1 12.4 0.1 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Ribonuclease 2-5A Transaldolase PF00923.14 EIE78210.1 - 4.5e-102 341.0 0.3 5.1e-102 340.8 0.2 1.0 1 0 0 1 1 1 1 Transaldolase DUF221 PF02714.10 EIE78211.1 - 6.8e-100 334.0 24.4 1.1e-99 333.4 16.9 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF221 DUF4463 PF14703.1 EIE78211.1 - 1.3e-12 48.0 0.4 2.8e-12 46.9 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) RSN1_TM PF13967.1 EIE78211.1 - 1.5e-12 47.3 2.1 1.5e-12 47.3 1.5 3.1 4 1 0 4 4 4 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 EIE78211.1 - 9e-12 44.7 0.0 2.1e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Phosphate metabolism protein RRM_1 PF00076.17 EIE78211.1 - 0.048 13.3 0.1 14 5.3 0.0 3.2 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RhoGEF PF00621.15 EIE78212.1 - 2.2e-06 27.6 0.0 5.2e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 RhoGEF domain Aldose_epim PF01263.15 EIE78216.1 - 1.9e-88 296.4 0.6 2.2e-88 296.2 0.4 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase ARPC4 PF05856.7 EIE78217.1 - 1.2e-49 167.9 5.8 6.3e-45 152.6 1.2 2.1 1 1 1 2 2 2 2 ARP2/3 complex 20 kDa subunit (ARPC4) DUF4201 PF13870.1 EIE78217.1 - 0.11 11.8 2.9 0.2 11.1 2.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Phage_GPL PF05926.6 EIE78218.1 - 1.9 8.3 35.6 4.1 7.2 2.6 5.3 1 1 3 5 5 5 0 Phage head completion protein (GPL) ScpA_ScpB PF02616.9 EIE78218.1 - 3.1 7.3 6.8 1.3 8.5 0.1 2.5 1 1 2 3 3 3 0 ScpA/B protein AhpC-TSA PF00578.16 EIE78219.1 - 1.6e-07 31.0 0.1 1.9e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family zf-CCHC_4 PF14392.1 EIE78221.1 - 6.4e-06 25.7 9.7 3.1e-05 23.5 1.2 2.2 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC PF00098.18 EIE78221.1 - 0.00014 21.6 0.4 0.00014 21.6 0.3 2.6 3 0 0 3 3 3 1 Zinc knuckle DUF2387 PF09526.5 EIE78221.1 - 0.44 10.4 2.2 0.59 10.0 1.5 1.4 1 1 0 1 1 1 0 Probable metal-binding protein (DUF2387) zf-RVT PF13966.1 EIE78223.1 - 0.01 16.1 1.2 0.018 15.3 0.8 1.4 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase Tcell_CD4_Cterm PF12104.3 EIE78226.1 - 0.08 12.5 0.1 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 T cell CD4 receptor C terminal region MFS_1 PF07690.11 EIE78229.1 - 0.044 12.4 3.1 0.077 11.7 2.1 1.3 1 1 0 1 1 1 0 Major Facilitator Superfamily Na_H_Exchanger PF00999.16 EIE78230.1 - 1.9e-16 59.5 4.0 2.5e-16 59.1 2.8 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.1 EIE78230.1 - 0.016 15.1 0.1 0.039 13.9 0.1 1.6 1 0 0 1 1 1 0 YrhC-like protein zf-RVT PF13966.1 EIE78231.1 - 3.9e-06 27.0 1.2 1.3e-05 25.3 0.3 2.1 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase HTH_Tnp_Tc3_2 PF01498.13 EIE78232.1 - 8.2e-12 45.0 0.2 1.7e-11 43.9 0.1 1.6 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.1 EIE78232.1 - 1.3e-05 25.2 0.0 2.7e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EIE78232.1 - 0.00035 20.1 0.0 0.00088 18.8 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain SpoIIID PF12116.3 EIE78232.1 - 0.0041 17.0 0.0 0.0081 16.0 0.0 1.6 1 0 0 1 1 1 1 Stage III sporulation protein D HTH_28 PF13518.1 EIE78232.1 - 0.01 15.8 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain DDE_3 PF13358.1 EIE78232.1 - 0.015 15.0 0.0 0.028 14.1 0.0 1.5 1 0 0 1 1 1 0 DDE superfamily endonuclease HTH_38 PF13936.1 EIE78232.1 - 0.016 14.7 0.0 0.036 13.6 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_IclR PF09339.5 EIE78232.1 - 0.021 14.4 0.0 0.048 13.2 0.0 1.6 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_24 PF13412.1 EIE78232.1 - 0.027 13.8 0.0 0.13 11.6 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_7 PF02796.10 EIE78232.1 - 0.052 13.4 0.3 2.4 8.0 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_Tnp_ISL3 PF13542.1 EIE78232.1 - 0.054 12.6 0.0 0.13 11.4 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_17 PF12728.2 EIE78232.1 - 0.075 13.2 0.1 0.38 11.0 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain DUF273 PF03314.9 EIE78232.1 - 0.099 11.9 0.3 4.8 6.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF273 Ras PF00071.17 EIE78234.1 - 1.2e-54 184.0 0.0 1.4e-54 183.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIE78234.1 - 6.2e-15 55.7 0.0 9.5e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIE78234.1 - 7e-08 31.8 0.0 1e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EIE78234.1 - 0.0028 17.1 0.0 0.013 14.9 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EIE78234.1 - 0.0033 16.6 0.0 0.0044 16.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EIE78234.1 - 0.073 12.2 0.0 0.089 11.9 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region mRNA_triPase PF02940.10 EIE78235.1 - 6.3e-15 55.5 0.2 8.5e-15 55.0 0.2 1.3 1 1 0 1 1 1 1 mRNA capping enzyme, beta chain PP2C PF00481.16 EIE78236.1 - 3e-36 125.1 0.0 3.8e-36 124.8 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 EIE78237.1 - 0.024 14.0 0.1 0.025 13.9 0.1 1.0 1 0 0 1 1 1 0 Protein phosphatase 2C Herpes_UL92 PF03048.9 EIE78237.1 - 0.044 13.3 1.2 0.045 13.3 0.8 1.0 1 0 0 1 1 1 0 UL92 family DUF2284 PF10050.4 EIE78237.1 - 0.048 13.2 0.9 0.049 13.2 0.7 1.0 1 0 0 1 1 1 0 Predicted metal-binding protein (DUF2284) DivIC PF04977.10 EIE78238.1 - 0.0022 17.4 2.0 0.0057 16.1 1.4 1.6 1 0 0 1 1 1 1 Septum formation initiator Lebercilin PF15619.1 EIE78238.1 - 0.012 15.0 2.6 0.012 15.0 1.8 1.6 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Herpes_BLRF2 PF05812.7 EIE78238.1 - 0.014 15.2 0.2 0.028 14.2 0.1 1.5 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein SlyX PF04102.7 EIE78238.1 - 0.017 15.5 2.5 0.039 14.3 1.7 1.6 1 0 0 1 1 1 0 SlyX DUF605 PF04652.11 EIE78238.1 - 0.1 11.9 5.7 0.1 11.9 4.0 1.1 1 0 0 1 1 1 0 Vta1 like HALZ PF02183.13 EIE78238.1 - 0.14 11.9 0.1 0.41 10.3 0.1 1.8 1 0 0 1 1 1 0 Homeobox associated leucine zipper Cep57_CLD_2 PF14197.1 EIE78238.1 - 0.56 10.1 4.8 1 9.3 1.7 2.2 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Pneumo_att_G PF05539.6 EIE78238.1 - 3.2 7.0 6.7 4.1 6.6 4.7 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G GFA PF04828.9 EIE78239.1 - 0.0092 15.9 0.8 0.0092 15.9 0.5 2.0 1 1 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.2 EIE78239.1 - 0.0093 15.7 7.5 0.11 12.2 5.2 2.2 1 1 0 1 1 1 1 Double zinc ribbon zf-C4pol PF14260.1 EIE78239.1 - 0.013 15.4 3.9 0.18 11.8 2.7 2.0 1 1 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta A2L_zn_ribbon PF08792.5 EIE78239.1 - 0.025 14.0 3.5 14 5.2 0.0 3.1 3 0 0 3 3 3 0 A2L zinc ribbon domain zinc_ribbon_2 PF13240.1 EIE78239.1 - 0.13 11.8 5.7 3.8 7.1 0.1 2.9 3 0 0 3 3 3 0 zinc-ribbon domain HypA PF01155.14 EIE78239.1 - 0.17 11.5 4.7 0.73 9.5 1.3 2.0 1 1 0 2 2 2 0 Hydrogenase expression/synthesis hypA family zinc-ribbons_6 PF07191.7 EIE78239.1 - 0.29 10.9 2.3 1.3 8.8 0.7 2.0 2 0 0 2 2 2 0 zinc-ribbons RRN7 PF11781.3 EIE78239.1 - 0.84 9.1 7.9 6.9 6.2 0.3 3.2 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 Spt4 PF06093.8 EIE78239.1 - 1.5 8.7 5.1 1.7 8.6 0.9 2.1 1 1 1 2 2 2 0 Spt4/RpoE2 zinc finger zf-ribbon_3 PF13248.1 EIE78239.1 - 1.7 7.9 8.5 0.77 9.0 2.1 2.5 1 1 1 2 2 2 0 zinc-ribbon domain PIF1 PF05970.9 EIE78240.1 - 2.3e-109 365.7 0.0 3.2e-109 365.2 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.1 EIE78240.1 - 7.3e-65 218.1 0.0 1.7e-64 216.9 0.0 1.7 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus Herpes_Helicase PF02689.9 EIE78240.1 - 2.1e-05 22.5 0.0 3.9e-05 21.6 0.0 1.3 1 0 0 1 1 1 1 Helicase AAA_30 PF13604.1 EIE78240.1 - 2.3e-05 24.0 0.0 9.9e-05 22.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 EIE78240.1 - 0.00016 21.5 0.0 0.00055 19.8 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EIE78240.1 - 0.00099 18.8 0.0 0.0022 17.6 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 EIE78240.1 - 0.016 14.9 0.0 0.049 13.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) UvrD_C_2 PF13538.1 EIE78240.1 - 0.064 13.4 0.0 0.17 12.0 0.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain PhoH PF02562.11 EIE78240.1 - 0.075 12.2 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein DAP3 PF10236.4 EIE78240.1 - 0.09 11.6 0.0 0.16 10.8 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.1 EIE78240.1 - 0.1 12.5 0.0 0.47 10.4 0.0 2.1 3 0 0 3 3 3 0 AAA ATPase domain TrwB_AAD_bind PF10412.4 EIE78240.1 - 0.14 10.7 0.0 0.23 10.0 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain T2SE PF00437.15 EIE78240.1 - 0.16 10.8 0.0 0.27 10.0 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein CsbD PF05532.7 EIE78242.1 - 0.013 15.1 1.1 0.038 13.6 0.8 1.8 1 0 0 1 1 1 0 CsbD-like GCR1_C PF12550.3 EIE78244.1 - 5.1e-26 90.3 0.7 5.1e-25 87.1 0.2 2.6 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes K_oxygenase PF13434.1 EIE78245.1 - 0.19 10.6 4.2 0.22 10.4 2.9 1.0 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) HTH_Tnp_Tc3_2 PF01498.13 EIE78246.1 - 5e-06 26.4 0.1 6e-06 26.2 0.1 1.2 1 0 0 1 1 1 1 Transposase DDE_Tnp_IS1595 PF12762.2 EIE78248.1 - 9.2e-15 54.7 0.0 5.8e-09 35.9 0.0 2.7 1 1 1 2 2 2 2 ISXO2-like transposase domain rve PF00665.21 EIE78249.1 - 4.7e-19 68.6 0.0 1.1e-18 67.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE78249.1 - 8e-17 61.3 0.9 1.5e-16 60.4 0.2 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE78249.1 - 4e-14 52.0 1.1 1.2e-13 50.4 0.7 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.1 EIE78249.1 - 0.00045 20.6 0.0 0.0011 19.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 EIE78249.1 - 0.00055 19.7 0.1 0.0019 18.0 0.1 2.0 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.12 EIE78250.1 - 0.00012 22.1 0.0 0.00016 21.6 0.0 1.2 1 0 0 1 1 1 1 Retrotransposon gag protein rve PF00665.21 EIE78251.1 - 1.1e-18 67.4 0.0 2.5e-18 66.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE78251.1 - 2.5e-16 59.6 0.6 5.4e-16 58.6 0.1 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE78251.1 - 9.1e-14 50.8 2.2 2.4e-13 49.5 1.5 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain HTH_Tnp_Tc3_2 PF01498.13 EIE78252.1 - 2.1e-10 40.5 0.8 3.8e-10 39.6 0.6 1.5 1 0 0 1 1 1 1 Transposase HTH_Tnp_4 PF13613.1 EIE78252.1 - 0.036 13.6 0.0 0.082 12.4 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE78253.1 - 1.1e-11 44.6 0.1 1.2e-11 44.4 0.1 1.0 1 0 0 1 1 1 1 Transposase Ribonucleas_3_2 PF11469.3 EIE78253.1 - 0.0029 17.8 0.1 0.0029 17.8 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease III HTH_29 PF13551.1 EIE78253.1 - 0.047 13.8 0.1 0.09 12.9 0.0 1.4 2 0 0 2 2 2 0 Winged helix-turn helix DDE_Tnp_ISAZ013 PF07592.6 EIE78253.1 - 0.075 11.7 0.0 0.075 11.7 0.0 1.0 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain rve PF00665.21 EIE78254.1 - 3.4e-20 72.3 0.0 1.7e-19 70.1 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 EIE78254.1 - 4.3e-20 71.9 0.1 2e-19 69.8 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.5 EIE78254.1 - 0.032 13.6 0.3 0.072 12.5 0.0 1.8 2 0 0 2 2 2 0 His(2)-Cys(2) zinc finger rve PF00665.21 EIE78255.1 - 1.1e-17 64.1 0.0 8e-17 61.4 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 EIE78255.1 - 5.4e-17 61.8 0.2 1.3e-16 60.6 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 EIE78255.1 - 1.4e-07 31.8 0.1 3.8e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Chromo PF00385.19 EIE78255.1 - 4.9e-07 29.3 0.5 1.2e-06 28.0 0.3 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVP PF00077.15 EIE78255.1 - 1.1e-06 28.4 0.2 8.1e-06 25.6 0.1 2.5 2 0 0 2 2 2 1 Retroviral aspartyl protease Retrotrans_gag PF03732.12 EIE78255.1 - 0.00063 19.7 2.3 0.0027 17.7 0.0 3.3 4 0 0 4 4 4 1 Retrotransposon gag protein gag-asp_proteas PF13975.1 EIE78255.1 - 0.00075 19.2 0.0 0.0017 18.1 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.5 EIE78255.1 - 0.01 15.3 0.2 0.088 12.3 0.1 2.4 2 0 0 2 2 2 0 Aspartyl protease FlxA PF14282.1 EIE78255.1 - 0.19 11.6 4.6 1.9 8.4 3.2 2.7 1 1 0 1 1 1 0 FlxA-like protein Tudor-knot PF11717.3 EIE78255.1 - 0.24 11.1 3.0 0.25 11.0 0.1 2.5 2 0 0 2 2 2 0 RNA binding activity-knot of a chromodomain IncA PF04156.9 EIE78255.1 - 2.2 7.8 6.3 5.2 6.6 4.4 1.6 1 0 0 1 1 1 0 IncA protein Retrotrans_gag PF03732.12 EIE78256.1 - 2.8e-10 40.1 0.0 6.1e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein RVP_2 PF08284.6 EIE78256.1 - 4.1e-10 39.7 0.3 8.9e-10 38.6 0.2 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 EIE78256.1 - 1.3e-05 25.5 0.0 2.9e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EIE78256.1 - 0.001 18.8 0.0 0.0021 17.8 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DDE_3 PF13358.1 EIE78257.1 - 5.4e-08 32.6 0.5 5.4e-08 32.6 0.4 1.8 2 1 0 2 2 2 1 DDE superfamily endonuclease NUDIX_4 PF14815.1 EIE78257.1 - 0.0084 15.5 0.3 0.012 15.0 0.2 1.3 1 0 0 1 1 1 1 NUDIX domain Imm35 PF15581.1 EIE78257.1 - 0.045 13.7 0.2 0.12 12.3 0.0 1.8 2 0 0 2 2 2 0 Immunity protein 35 INCA1 PF15142.1 EIE78257.1 - 0.093 12.5 0.2 0.38 10.5 0.0 1.9 2 1 1 3 3 3 0 INCA1 Phage_integrase PF00589.17 EIE78258.1 - 0.00062 19.4 0.0 0.16 11.6 0.0 2.1 1 1 1 2 2 2 2 Phage integrase family Chromo PF00385.19 EIE78259.1 - 2.2e-09 36.8 0.2 6.2e-09 35.3 0.1 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF2870 PF11069.3 EIE78259.1 - 0.045 13.7 1.1 0.088 12.8 0.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2870) TcdB_N PF12918.2 EIE78259.1 - 0.12 12.4 3.7 0.13 12.4 0.0 2.4 2 0 0 2 2 2 0 TcdB toxin N-terminal helical domain SAS4 PF15460.1 EIE78259.1 - 4.4 7.2 8.5 0.73 9.7 2.0 2.5 2 1 1 3 3 3 0 Something about silencing, SAS, complex subunit 4 DUF1764 PF08576.5 EIE78259.1 - 8.6 7.2 9.6 28 5.5 2.9 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) DUF2798 PF11391.3 EIE78260.1 - 0.5 10.1 8.0 2.6e+02 1.4 5.6 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2798) rve PF00665.21 EIE78262.1 - 7.1e-23 80.9 0.0 1.7e-22 79.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE78262.1 - 4e-15 55.7 0.4 9.3e-15 54.5 0.2 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE78262.1 - 3.3e-11 42.6 1.1 8e-11 41.4 0.7 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 EIE78262.1 - 0.0013 18.0 0.1 0.0034 16.7 0.1 1.8 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Asp_protease_2 PF13650.1 EIE78262.1 - 0.0031 17.9 0.2 0.0078 16.6 0.2 1.8 1 0 0 1 1 1 1 Aspartyl protease rve_3 PF13683.1 EIE78262.1 - 0.0068 15.9 0.2 0.041 13.4 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain Asp_protease PF09668.5 EIE78262.1 - 0.036 13.6 0.1 0.1 12.1 0.1 1.8 1 1 0 1 1 1 0 Aspartyl protease Musclin PF11037.3 EIE78263.1 - 0.1 12.2 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 Insulin-resistance promoting peptide in skeletal muscle zf-C2H2_4 PF13894.1 EIE78264.1 - 0.00023 21.2 4.1 0.035 14.4 0.7 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EIE78264.1 - 0.4 11.1 3.9 5.8 7.4 0.1 2.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type DDE_3 PF13358.1 EIE78266.1 - 1e-11 44.7 0.0 2.4e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease FliT PF05400.8 EIE78266.1 - 0.14 12.5 0.4 0.14 12.5 0.3 2.7 3 0 0 3 3 3 0 Flagellar protein FliT Cas_Csm6 PF09659.5 EIE78267.1 - 0.04 12.5 2.2 0.046 12.3 1.5 1.0 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csm6) ICA69 PF04629.9 EIE78267.1 - 0.069 13.1 4.0 0.071 13.0 2.7 1.0 1 0 0 1 1 1 0 Islet cell autoantigen ICA69, C-terminal domain BLVR PF06375.6 EIE78267.1 - 0.096 12.5 10.5 0.11 12.3 7.2 1.1 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) EIIBC-GUT_N PF03612.9 EIE78267.1 - 0.13 11.8 1.6 0.15 11.7 1.1 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF2098 PF09871.4 EIE78267.1 - 0.86 9.5 6.8 1.1 9.2 4.7 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2098) OAD_gamma PF04277.8 EIE78267.1 - 1.1 9.6 3.8 1.6 9.1 2.6 1.3 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Bact_transglu_N PF08379.5 EIE78268.1 - 0.73 10.1 4.5 0.14 12.4 0.7 1.7 2 0 0 2 2 2 0 Bacterial transglutaminase-like N-terminal region Cyclin_N PF00134.18 EIE78269.1 - 8.3e-10 38.3 0.2 1.1e-09 37.9 0.2 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 EIE78269.1 - 4.8e-09 36.7 0.1 7.3e-09 36.2 0.1 1.3 1 0 0 1 1 1 1 Cyclin Minor_tail_Z PF06763.6 EIE78269.1 - 0.11 12.1 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 Prophage minor tail protein Z (GPZ) M20_dimer PF07687.9 EIE78270.1 - 1.8e-10 40.5 0.0 4.5e-10 39.2 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.23 EIE78270.1 - 2.7e-07 30.2 0.0 6.6e-07 29.0 0.0 1.6 1 1 1 2 2 2 1 Peptidase family M20/M25/M40 AMP-binding PF00501.23 EIE78271.1 - 6.2e-47 159.9 0.0 1.6e-46 158.5 0.0 1.7 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EIE78271.1 - 1.1e-38 132.5 0.0 4.9e-38 130.4 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein PP-binding PF00550.20 EIE78271.1 - 1e-12 48.1 0.2 7.3e-12 45.3 0.0 2.3 2 0 0 2 2 2 1 Phosphopantetheine attachment site Epimerase PF01370.16 EIE78271.1 - 7.9e-05 22.1 0.0 0.00034 20.1 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EIE78271.1 - 0.0029 16.5 0.1 0.068 12.0 0.0 2.3 2 0 0 2 2 2 1 RmlD substrate binding domain adh_short PF00106.20 EIE78271.1 - 0.11 12.4 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 short chain dehydrogenase NAD_binding_10 PF13460.1 EIE78271.1 - 0.15 12.0 0.0 0.47 10.4 0.0 1.9 1 0 0 1 1 1 0 NADH(P)-binding Plectin PF00681.15 EIE78273.1 - 0.064 12.7 0.0 0.092 12.2 0.0 1.3 1 0 0 1 1 1 0 Plectin repeat CTP_transf_1 PF01148.15 EIE78274.1 - 5.7e-48 163.8 2.8 6.3e-48 163.6 2.0 1.0 1 0 0 1 1 1 1 Cytidylyltransferase family DUF389 PF04087.9 EIE78274.1 - 0.1 12.5 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF389) PgaD PF13994.1 EIE78274.1 - 0.11 11.9 2.5 0.15 11.4 1.7 1.2 1 0 0 1 1 1 0 PgaD-like protein M20_dimer PF07687.9 EIE78275.1 - 1.8e-10 40.5 0.0 4.5e-10 39.2 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.23 EIE78275.1 - 2.7e-07 30.2 0.0 6.6e-07 29.0 0.0 1.6 1 1 1 2 2 2 1 Peptidase family M20/M25/M40 ABC2_membrane PF01061.19 EIE78276.1 - 8.8e-83 276.6 57.0 1.5e-48 164.7 15.3 3.4 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.22 EIE78276.1 - 8.5e-34 116.8 0.2 5.7e-18 65.5 0.0 3.3 4 0 0 4 4 3 2 ABC transporter PDR_CDR PF06422.7 EIE78276.1 - 1.1e-24 86.0 3.0 4.5e-16 58.3 0.0 3.9 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.1 EIE78276.1 - 4e-10 39.6 0.0 1.2e-09 38.1 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal ABC2_membrane_3 PF12698.2 EIE78276.1 - 1.2e-05 24.4 19.9 1.2e-05 24.4 13.8 3.1 2 1 0 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.1 EIE78276.1 - 1.4e-05 25.2 0.6 0.2 11.5 0.0 2.7 1 1 0 2 2 2 2 AAA domain DUF258 PF03193.11 EIE78276.1 - 5.5e-05 22.3 0.0 0.0033 16.6 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EIE78276.1 - 0.00031 20.2 0.2 0.0083 15.6 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.1 EIE78276.1 - 0.00044 19.7 0.0 0.0098 15.3 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 EIE78276.1 - 0.0015 18.7 0.0 0.14 12.2 0.0 3.2 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.7 EIE78276.1 - 0.01 14.9 0.0 0.23 10.5 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_18 PF13238.1 EIE78276.1 - 0.026 14.8 0.3 0.33 11.2 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.1 EIE78276.1 - 0.028 14.3 0.1 0.54 10.2 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain UPF0079 PF02367.12 EIE78276.1 - 0.033 13.8 1.2 0.37 10.4 0.2 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_33 PF13671.1 EIE78276.1 - 0.037 13.8 0.0 0.52 10.1 0.0 2.7 3 0 0 3 3 2 0 AAA domain AAA_17 PF13207.1 EIE78276.1 - 0.038 14.8 0.0 0.75 10.6 0.0 2.9 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 EIE78276.1 - 0.05 13.0 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain SbcCD_C PF13558.1 EIE78276.1 - 0.051 13.4 0.0 0.24 11.3 0.0 2.2 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_19 PF13245.1 EIE78276.1 - 0.15 11.7 0.1 1.9 8.2 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain Miro PF08477.8 EIE78276.1 - 0.24 11.9 0.0 7.2 7.1 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein AAA_15 PF13175.1 EIE78276.1 - 0.32 9.9 0.0 6 5.7 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.1 EIE78276.1 - 4.6 7.1 6.4 0.34 10.8 0.2 2.3 3 0 0 3 3 3 0 AAA domain MTHFR PF02219.12 EIE78277.1 - 9.1e-115 382.6 0.0 1.3e-114 382.2 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase AP_endonuc_2 PF01261.19 EIE78277.1 - 0.13 11.5 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel DUF2315 PF10231.4 EIE78278.1 - 1.5e-11 44.2 2.5 1.8e-11 43.9 1.8 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2315) HAD_2 PF13419.1 EIE78278.1 - 0.047 13.9 0.1 0.055 13.6 0.1 1.0 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase V-ATPase_H_C PF11698.3 EIE78279.1 - 1.2e-42 144.5 1.7 1.7e-41 140.8 0.2 2.4 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_N PF03224.9 EIE78279.1 - 4.2e-35 121.3 6.0 1.7e-26 93.0 0.2 3.0 3 0 0 3 3 3 2 V-ATPase subunit H Arm PF00514.18 EIE78279.1 - 0.00036 20.2 0.1 1.3 8.9 0.0 3.5 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EIE78279.1 - 0.039 14.2 0.4 2.1 8.7 0.0 3.1 2 2 0 2 2 2 0 HEAT repeats HEAT PF02985.17 EIE78279.1 - 0.046 13.8 0.0 0.32 11.2 0.0 2.4 2 0 0 2 2 2 0 HEAT repeat Tmpp129 PF10272.4 EIE78279.1 - 0.059 12.1 0.3 0.089 11.4 0.2 1.3 1 0 0 1 1 1 0 Putative transmembrane protein precursor Mitofilin PF09731.4 EIE78280.1 - 1.3e-80 271.7 48.5 6.3e-68 229.8 28.2 2.2 1 1 1 2 2 2 2 Mitochondrial inner membrane protein Matrilin_ccoil PF10393.4 EIE78280.1 - 0.012 15.0 0.7 0.068 12.5 0.2 2.6 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin VitK2_biosynth PF02621.9 EIE78280.1 - 0.92 8.6 11.0 0.041 13.0 2.0 2.4 2 0 0 2 2 2 0 Menaquinone biosynthesis Methyltransf_11 PF08241.7 EIE78281.1 - 3.9e-13 49.7 0.0 8.4e-13 48.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIE78281.1 - 2.6e-10 40.0 0.1 2.2e-09 37.0 0.1 2.2 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIE78281.1 - 8.4e-10 38.5 0.0 1.4e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIE78281.1 - 3.1e-09 37.1 0.0 1.2e-08 35.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIE78281.1 - 6.2e-09 36.2 0.1 3.8e-08 33.7 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIE78281.1 - 1.1e-06 27.8 0.0 3.1e-06 26.4 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EIE78281.1 - 1.1e-05 25.9 0.0 4.4e-05 24.0 0.0 2.0 2 2 0 2 2 2 1 Methyltransferase domain Methyltransf_2 PF00891.13 EIE78281.1 - 0.00036 19.8 0.0 0.00057 19.1 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_4 PF02390.12 EIE78281.1 - 0.0021 17.1 0.0 0.0049 15.9 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_29 PF03141.11 EIE78281.1 - 0.0023 16.3 0.2 0.0074 14.6 0.2 1.7 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MetW PF07021.7 EIE78281.1 - 0.0053 16.1 0.0 0.0084 15.4 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW CMAS PF02353.15 EIE78281.1 - 0.015 14.4 0.0 0.019 14.0 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_8 PF05148.10 EIE78281.1 - 0.031 13.8 0.0 0.053 13.1 0.0 1.4 1 1 0 1 1 1 0 Hypothetical methyltransferase Corona_6B_7B PF03262.8 EIE78281.1 - 0.041 13.1 0.0 0.076 12.2 0.0 1.4 1 0 0 1 1 1 0 Coronavirus 6B/7B protein TehB PF03848.9 EIE78281.1 - 0.063 12.4 0.0 0.098 11.8 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB FmrO PF07091.6 EIE78281.1 - 0.089 11.7 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Methyltransf_9 PF08003.6 EIE78281.1 - 0.098 11.3 0.0 0.21 10.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) Methyltransf_26 PF13659.1 EIE78281.1 - 0.11 12.4 0.0 0.26 11.3 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain DUF2683 PF10884.3 EIE78281.1 - 0.12 12.2 0.1 6.4 6.7 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2683) zf-C2H2_4 PF13894.1 EIE78282.1 - 0.0061 16.8 1.7 0.0061 16.8 1.2 1.9 2 0 0 2 2 2 1 C2H2-type zinc finger BLVR PF06375.6 EIE78282.1 - 0.0098 15.7 1.7 0.013 15.3 1.2 1.2 1 0 0 1 1 1 1 Bovine leukaemia virus receptor (BLVR) NST1 PF13945.1 EIE78282.1 - 0.076 13.0 3.5 0.1 12.6 2.4 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator zf-H2C2_2 PF13465.1 EIE78282.1 - 2.1 8.7 9.3 4.6 7.7 3.7 2.9 2 1 0 2 2 2 0 Zinc-finger double domain zf-C2H2 PF00096.21 EIE78282.1 - 2.6 8.5 7.2 0.15 12.4 1.2 1.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type ADK PF00406.17 EIE78283.1 - 8.6e-42 142.5 0.0 9.9e-42 142.3 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.1 EIE78283.1 - 1e-07 32.8 0.0 1.3e-07 32.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EIE78283.1 - 6.7e-07 29.6 0.0 7.8e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EIE78283.1 - 8.8e-05 22.4 0.0 0.00013 21.8 0.0 1.3 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EIE78283.1 - 0.0061 15.6 0.0 0.0066 15.5 0.0 1.3 1 1 0 1 1 1 1 Zeta toxin Peptidase_M18 PF02127.10 EIE78284.1 - 2.7e-170 566.5 0.1 3.1e-170 566.3 0.1 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 EIE78284.1 - 6.8e-08 31.6 1.7 1e-06 27.7 0.2 2.1 1 1 0 2 2 2 2 M42 glutamyl aminopeptidase SH3_1 PF00018.23 EIE78285.1 - 3.5e-14 51.9 0.1 5.1e-14 51.3 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EIE78285.1 - 1.7e-09 37.0 0.0 3.5e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EIE78285.1 - 1.5e-07 30.7 0.0 2.5e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain HrpB1_HrpK PF09613.5 EIE78285.1 - 0.028 13.9 0.0 0.053 13.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB1_HrpK) HAMP PF00672.20 EIE78286.1 - 9e-155 503.1 65.2 5.3e-09 36.1 0.3 20.3 19 0 0 19 19 19 18 HAMP domain HATPase_c PF02518.21 EIE78286.1 - 3.8e-29 100.6 0.1 1.8e-28 98.4 0.1 2.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EIE78286.1 - 1.1e-27 96.2 2.1 5.2e-25 87.6 0.1 2.9 2 0 0 2 2 2 2 Response regulator receiver domain HisKA PF00512.20 EIE78286.1 - 1.4e-17 63.3 0.6 1.4e-17 63.3 0.4 4.4 5 0 0 5 5 5 1 His Kinase A (phospho-acceptor) domain HTH_6 PF01418.12 EIE78286.1 - 2.3e-09 36.8 5.1 30 4.4 0.0 12.3 14 0 0 14 14 14 0 Helix-turn-helix domain, rpiR family SpoIIID PF12116.3 EIE78286.1 - 0.00059 19.7 37.4 14 5.6 0.0 15.5 16 0 0 16 16 16 0 Stage III sporulation protein D HMG_box PF00505.14 EIE78286.1 - 0.038 14.2 0.0 49 4.3 0.0 3.9 3 0 0 3 3 3 0 HMG (high mobility group) box N6_N4_Mtase PF01555.13 EIE78286.1 - 0.081 12.3 0.0 2e+02 1.3 0.0 5.1 5 0 0 5 5 5 0 DNA methylase Root_cap PF06830.6 EIE78286.1 - 0.2 11.4 0.0 0.84 9.5 0.0 2.1 1 0 0 1 1 1 0 Root cap Pox_A_type_inc PF04508.7 EIE78286.1 - 0.3 10.9 8.5 3.8 7.5 0.0 6.4 8 0 0 8 8 8 0 Viral A-type inclusion protein repeat Se-cys_synth_N PF12390.3 EIE78286.1 - 3.1 7.9 7.0 2.1e+02 2.1 0.0 6.6 8 0 0 8 8 8 0 Selenocysteine synthase N terminal Tcf25 PF04910.9 EIE78287.1 - 1.8e-78 264.0 5.7 1.8e-78 264.0 3.9 2.1 2 0 0 2 2 2 1 Transcriptional repressor TCF25 Bgal_small_N PF02929.12 EIE78287.1 - 0.0064 15.5 0.0 0.013 14.5 0.0 1.5 1 0 0 1 1 1 1 Beta galactosidase small chain Stm1_N PF09598.5 EIE78287.1 - 0.12 13.0 10.4 0.34 11.6 7.2 1.9 1 0 0 1 1 1 0 Stm1 Phosphoesterase PF04185.9 EIE78287.1 - 0.65 9.1 5.5 0.066 12.3 0.2 1.8 2 0 0 2 2 2 0 Phosphoesterase family Daxx PF03344.10 EIE78287.1 - 4.3 5.7 32.1 3.5 5.9 15.5 2.1 2 0 0 2 2 2 0 Daxx Family DUF775 PF05603.7 EIE78289.1 - 2.4e-51 174.1 0.1 2.9e-51 173.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF775) Helicase_IV_N PF12462.3 EIE78289.1 - 0.00065 19.3 0.1 0.031 13.9 0.0 2.1 2 0 0 2 2 2 2 DNA helicase IV / RNA helicase N terminal Mg_trans_NIPA PF05653.9 EIE78290.1 - 2.4e-16 59.5 7.5 3.2e-16 59.1 5.2 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA DUF843 PF05814.6 EIE78290.1 - 0.013 15.2 2.2 0.013 15.2 1.6 2.1 2 1 1 3 3 3 0 Baculovirus protein of unknown function (DUF843) HlyIII PF03006.15 EIE78290.1 - 0.027 13.8 5.7 0.036 13.4 4.0 1.1 1 0 0 1 1 1 0 Haemolysin-III related Got1 PF04178.7 EIE78290.1 - 0.79 9.8 6.6 1.3 9.1 0.1 2.2 1 1 1 2 2 2 0 Got1/Sft2-like family GRASP55_65 PF04495.9 EIE78291.1 - 5.1e-31 107.4 0.0 6e-31 107.2 0.0 1.1 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain MIS13 PF08202.6 EIE78291.1 - 0.052 12.6 0.0 0.073 12.1 0.0 1.1 1 0 0 1 1 1 0 Mis12-Mtw1 protein family DUF3818 PF12825.2 EIE78292.1 - 5.7e-78 261.9 7.7 2.2e-77 260.0 5.3 2.0 1 1 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 EIE78292.1 - 7.6e-14 51.4 7.4 1.6e-12 47.2 5.1 2.7 1 1 0 1 1 1 1 PX-associated PX PF00787.19 EIE78292.1 - 2.8e-11 43.2 0.1 8.8e-11 41.5 0.1 1.9 1 0 0 1 1 1 1 PX domain zf-RVT PF13966.1 EIE78293.1 - 7.3e-05 23.0 0.6 0.0004 20.6 0.2 2.0 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase PIN_4 PF13638.1 EIE78294.1 - 0.0055 16.8 1.0 0.018 15.1 0.1 2.0 2 0 0 2 2 2 1 PIN domain Glyco_hydro_15 PF00723.16 EIE78295.1 - 4.2e-119 398.0 0.0 6.2e-118 394.2 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 ACI44 PF15270.1 EIE78297.1 - 0.026 14.5 0.3 0.068 13.1 0.1 1.7 2 0 0 2 2 2 0 Metallo-carboxypeptidase inhibitor Exo_endo_phos PF03372.18 EIE78298.1 - 2.7e-14 53.7 4.6 5.8e-14 52.6 3.2 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EIE78298.1 - 6.7e-11 41.8 1.8 1.7e-10 40.5 1.2 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase zf-CCHC PF00098.18 EIE78298.1 - 0.0018 18.1 1.9 0.0036 17.1 1.3 1.5 1 0 0 1 1 1 1 Zinc knuckle Aa_trans PF01490.13 EIE78299.1 - 1.3e-16 60.1 29.2 2e-16 59.5 20.2 1.3 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF4303 PF14136.1 EIE78300.1 - 0.047 13.3 0.0 0.066 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4303) Pentapeptide_4 PF13599.1 EIE78301.1 - 0.0032 17.2 0.6 0.0038 16.9 0.4 1.3 1 1 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.1 EIE78301.1 - 0.037 13.9 1.0 0.056 13.3 0.7 1.2 1 0 0 1 1 1 0 Pentapeptide repeats (9 copies) Pentapeptide PF00805.17 EIE78301.1 - 0.13 11.5 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Pentapeptide repeats (8 copies) DUF2689 PF10894.3 EIE78301.1 - 0.18 11.6 0.9 0.42 10.4 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2689) Oxidored_q2 PF00420.19 EIE78301.1 - 0.55 9.8 5.8 0.64 9.6 4.0 1.1 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Kelch_1 PF01344.20 EIE78302.1 - 0.0088 15.5 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 Kelch motif Kelch_6 PF13964.1 EIE78302.1 - 0.017 15.2 0.0 0.026 14.7 0.0 1.3 1 0 0 1 1 1 0 Kelch motif Kelch_4 PF13418.1 EIE78302.1 - 0.065 13.0 0.5 0.15 11.8 0.3 1.7 1 1 0 1 1 1 0 Galactose oxidase, central domain TagA PF12561.3 EIE78302.1 - 0.071 13.1 0.0 0.086 12.8 0.0 1.1 1 0 0 1 1 1 0 ToxR activated gene A lipoprotein Pkinase PF00069.20 EIE78303.1 - 1.4e-71 240.6 0.2 1.4e-71 240.6 0.2 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE78303.1 - 5.2e-51 173.2 0.2 5.2e-51 173.2 0.2 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.23 EIE78303.1 - 1.6e-19 70.0 0.0 5.1e-19 68.4 0.0 2.0 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.1 EIE78303.1 - 1.5e-09 37.2 0.2 3e-08 32.9 0.0 2.3 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 EIE78303.1 - 0.0012 18.6 0.0 0.084 12.5 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EIE78303.1 - 0.025 13.6 0.2 0.049 12.6 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Lipase_GDSL_3 PF14606.1 EIE78303.1 - 4.4 7.0 6.0 26 4.4 0.1 3.1 4 0 0 4 4 4 0 GDSL-like Lipase/Acylhydrolase family MIF4G PF02854.14 EIE78304.1 - 2.1e-34 118.8 0.2 5e-34 117.5 0.2 1.6 1 0 0 1 1 1 1 MIF4G domain Macoilin PF09726.4 EIE78304.1 - 7.1 4.7 29.8 0.32 9.2 16.8 1.5 2 0 0 2 2 2 0 Transmembrane protein Polysacc_deac_1 PF01522.16 EIE78305.1 - 5.7e-25 87.3 0.1 9.3e-25 86.6 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase HEM4 PF02602.10 EIE78306.1 - 5.4e-23 81.4 0.0 5.8e-23 81.3 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD HMG_box PF00505.14 EIE78307.1 - 1.4e-17 63.6 2.5 2.5e-17 62.9 1.7 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EIE78307.1 - 6.9e-08 32.7 1.0 1.3e-07 31.8 0.7 1.4 1 0 0 1 1 1 1 HMG-box domain COX4 PF02936.9 EIE78307.1 - 0.0071 16.0 0.1 0.013 15.2 0.1 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV PH_9 PF15410.1 EIE78309.1 - 5.7e-41 139.4 0.3 1.7e-40 137.8 0.2 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain Sec7 PF01369.15 EIE78309.1 - 3.3e-24 85.6 8.9 4.5e-23 81.9 4.1 3.0 2 1 0 2 2 2 1 Sec7 domain PH PF00169.24 EIE78309.1 - 7.1e-09 35.8 0.2 2.2e-08 34.2 0.1 1.8 1 0 0 1 1 1 1 PH domain Kri1_C PF12936.2 EIE78310.1 - 8e-24 83.4 0.3 8e-24 83.4 0.2 4.3 4 1 0 4 4 4 1 KRI1-like family C-terminal Kri1 PF05178.7 EIE78310.1 - 8.7e-24 83.7 7.4 8.7e-24 83.7 5.1 5.0 4 1 1 5 5 5 1 KRI1-like family HTH_32 PF13565.1 EIE78310.1 - 8.5 7.2 10.6 0.62 10.8 1.5 3.0 3 0 0 3 3 3 0 Homeodomain-like domain Pkinase PF00069.20 EIE78311.1 - 7.1e-14 51.5 0.0 1.1e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE78311.1 - 5.2e-09 35.5 0.0 7.6e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ribosom_S12_S23 PF00164.20 EIE78312.1 - 3.2e-41 139.5 0.7 3.7e-41 139.3 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 CTP_synth_N PF06418.9 EIE78314.1 - 1.1e-121 405.1 0.1 1.5e-121 404.7 0.1 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 EIE78314.1 - 6e-57 192.1 0.0 9.1e-57 191.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EIE78314.1 - 1.1e-06 28.3 0.0 2.5e-06 27.0 0.0 1.6 1 1 0 1 1 1 1 Peptidase C26 CbiA PF01656.18 EIE78314.1 - 0.0096 15.3 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain PPTA PF01239.17 EIE78315.1 - 3.1e-22 76.9 8.4 9.5e-08 31.0 0.1 4.2 5 0 0 5 5 5 3 Protein prenyltransferase alpha subunit repeat HECT PF00632.20 EIE78316.1 - 9.1e-99 330.5 0.2 3.2e-98 328.7 0.0 2.1 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) DUF4414 PF14377.1 EIE78316.1 - 2.3e-12 46.7 8.1 2.8e-12 46.4 4.3 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4414) GOLD_2 PF13897.1 EIE78317.1 - 0.08 13.1 2.1 0.38 10.9 0.6 2.5 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking Serinc PF03348.10 EIE78317.1 - 0.28 9.8 2.8 0.12 11.0 0.3 1.5 2 0 0 2 2 2 0 Serine incorporator (Serinc) DUF913 PF06025.7 EIE78318.1 - 4.8e-48 163.8 1.8 1.2e-38 132.8 0.4 3.2 1 1 1 2 2 2 2 Domain of Unknown Function (DUF913) DUF908 PF06012.7 EIE78318.1 - 2.3e-08 33.7 0.1 4.7e-08 32.7 0.1 1.6 1 0 0 1 1 1 1 Domain of Unknown Function (DUF908) RICTOR_M PF14666.1 EIE78318.1 - 0.033 13.1 0.1 0.12 11.3 0.0 2.0 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, middle domain DUF3020 PF11223.3 EIE78319.1 - 1e-09 38.5 0.3 1.9e-09 37.7 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3020) zf-RING_2 PF13639.1 EIE78320.1 - 4e-14 52.1 5.7 6.2e-14 51.5 4.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EIE78320.1 - 1.5e-09 37.8 5.1 3.4e-09 36.6 3.5 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EIE78320.1 - 6.8e-08 32.4 6.8 1.1e-07 31.7 4.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EIE78320.1 - 7.6e-08 31.9 3.5 1.2e-07 31.3 2.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIE78320.1 - 8.9e-07 28.4 7.0 1.5e-06 27.7 4.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIE78320.1 - 2.3e-05 24.0 4.1 3.7e-05 23.3 2.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EIE78320.1 - 0.0003 20.5 4.0 0.0007 19.3 2.8 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger ARL2_Bind_BART PF11527.3 EIE78320.1 - 0.00048 19.9 1.4 0.00087 19.0 0.7 1.7 1 1 0 1 1 1 1 The ARF-like 2 binding protein BART zf-RING_UBOX PF13445.1 EIE78320.1 - 0.00058 19.5 1.5 0.00058 19.5 1.1 2.3 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.1 EIE78320.1 - 0.00083 18.8 1.4 0.0017 17.8 1.0 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-TFIIIC PF12660.2 EIE78320.1 - 0.01 15.7 0.8 0.023 14.5 0.6 1.6 1 0 0 1 1 1 0 Putative zinc-finger of transcription factor IIIC complex zf-Nse PF11789.3 EIE78320.1 - 0.022 14.2 2.4 0.048 13.1 1.7 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Tex_N PF09371.5 EIE78320.1 - 0.035 13.4 0.0 0.06 12.6 0.0 1.5 1 1 0 1 1 1 0 Tex-like protein N-terminal domain U-box PF04564.10 EIE78320.1 - 0.072 13.0 0.0 0.9 9.5 0.0 2.2 2 0 0 2 2 2 0 U-box domain Prok-RING_1 PF14446.1 EIE78320.1 - 0.17 11.6 2.8 0.87 9.3 0.2 2.1 1 1 0 2 2 2 0 Prokaryotic RING finger family 1 MRP-S27 PF10037.4 EIE78320.1 - 0.18 10.6 2.8 0.32 9.8 1.9 1.4 1 1 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 zf-RING_4 PF14570.1 EIE78320.1 - 0.61 9.7 4.1 1.1 8.9 2.9 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 EIE78320.1 - 0.72 9.7 4.1 2.6 7.9 2.8 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Baculo_IE-1 PF05290.6 EIE78320.1 - 1.4 8.6 6.1 4.2 7.1 1.5 2.1 1 1 1 2 2 2 0 Baculovirus immediate-early protein (IE-0) Rtf2 PF04641.7 EIE78320.1 - 1.5 7.9 4.9 0.22 10.6 0.6 1.6 2 0 0 2 2 2 0 Rtf2 RING-finger Grp1_Fun34_YaaH PF01184.14 EIE78321.1 - 1.5e-68 230.2 16.2 1.9e-68 229.8 11.3 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family ThuA PF06283.6 EIE78322.1 - 0.011 15.4 2.6 0.69 9.5 0.1 2.1 2 0 0 2 2 2 0 Trehalose utilisation PTS_IIB PF02302.12 EIE78322.1 - 0.12 12.8 1.9 0.15 12.5 0.2 1.9 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIB subunit BUD22 PF09073.5 EIE78322.1 - 0.64 9.0 13.4 0.82 8.6 9.3 1.1 1 0 0 1 1 1 0 BUD22 Perilipin PF03036.11 EIE78323.1 - 5.1e-05 22.2 16.3 0.099 11.4 0.1 3.3 2 1 1 3 3 3 3 Perilipin family HD_assoc PF13286.1 EIE78323.1 - 0.097 12.9 0.2 0.32 11.2 0.1 2.0 2 0 0 2 2 2 0 Phosphohydrolase-associated domain DUF3767 PF12597.3 EIE78324.1 - 4.4e-16 58.5 0.0 4.9e-16 58.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) DUF3943 PF13084.1 EIE78324.1 - 0.13 11.8 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3943) Kelch_3 PF13415.1 EIE78325.1 - 2e-17 62.8 0.7 1.7e-07 31.2 0.0 5.5 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_4 PF13418.1 EIE78325.1 - 1.5e-16 59.9 0.3 0.0021 17.7 0.0 4.9 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.1 EIE78325.1 - 2.2e-16 59.3 0.1 0.00068 19.5 0.0 3.7 3 0 0 3 3 3 3 Kelch motif Kelch_6 PF13964.1 EIE78325.1 - 4e-14 52.0 0.7 0.00059 19.8 0.0 4.6 4 0 0 4 4 4 3 Kelch motif Kelch_1 PF01344.20 EIE78325.1 - 7.8e-14 50.9 0.1 0.0022 17.5 0.0 4.2 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.10 EIE78325.1 - 4e-13 48.5 0.0 0.0046 16.6 0.0 4.5 4 0 0 4 4 4 3 Kelch motif BTB PF00651.26 EIE78325.1 - 9.5e-13 48.1 0.1 1.8e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain FAM60A PF15396.1 EIE78326.1 - 0.0031 17.2 0.3 0.0037 17.0 0.2 1.2 1 0 0 1 1 1 1 Protein Family FAM60A CDC37_N PF03234.9 EIE78326.1 - 0.018 15.3 0.9 0.023 15.0 0.6 1.2 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding Ras PF00071.17 EIE78328.1 - 1.2e-34 118.9 0.0 3.6e-34 117.4 0.0 1.8 2 0 0 2 2 2 1 Ras family Sel1 PF08238.7 EIE78328.1 - 4.7e-26 90.6 36.2 5.1e-08 33.2 0.9 9.1 10 1 0 10 10 10 5 Sel1 repeat Arf PF00025.16 EIE78328.1 - 5.4e-07 29.0 0.0 9.1e-07 28.2 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 EIE78328.1 - 1.6e-06 28.6 0.0 4.1e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 EIE78328.1 - 8.4e-05 22.0 0.0 0.00023 20.6 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain TPR_6 PF13174.1 EIE78328.1 - 1.5 9.4 21.7 10 6.8 0.5 6.5 6 0 0 6 6 6 0 Tetratricopeptide repeat Sod_Fe_C PF02777.13 EIE78329.1 - 2.9e-42 142.8 0.3 5.2e-42 141.9 0.2 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EIE78329.1 - 2.2e-30 104.7 3.2 5e-30 103.6 2.2 1.6 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain MtrH PF02007.13 EIE78329.1 - 0.12 11.3 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase MtrH subunit Alk_phosphatase PF00245.15 EIE78330.1 - 6.5e-82 275.4 0.0 8.6e-82 275.0 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.13 EIE78330.1 - 0.002 17.5 0.1 0.0038 16.6 0.1 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily APS_kinase PF01583.15 EIE78331.1 - 2.2e-71 238.6 0.0 2.6e-71 238.3 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.1 EIE78331.1 - 1e-10 41.6 0.0 1.4e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EIE78331.1 - 7.5e-06 26.7 0.0 1.6e-05 25.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EIE78331.1 - 5e-05 23.6 0.2 0.00042 20.6 0.2 2.5 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 EIE78331.1 - 0.0003 20.0 0.0 0.00031 20.0 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_29 PF13555.1 EIE78331.1 - 0.0014 18.0 0.0 0.0025 17.2 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain CPT PF07931.7 EIE78331.1 - 0.017 14.7 0.1 0.43 10.1 0.1 2.3 1 1 1 2 2 2 0 Chloramphenicol phosphotransferase-like protein Zeta_toxin PF06414.7 EIE78331.1 - 0.041 12.9 0.0 0.069 12.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.22 EIE78331.1 - 0.065 13.5 0.0 0.12 12.7 0.0 1.4 1 1 0 1 1 1 0 ABC transporter MobB PF03205.9 EIE78331.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Spc42p PF11544.3 EIE78332.1 - 0.00087 19.1 4.3 0.00087 19.1 3.0 2.7 4 0 0 4 4 4 1 Spindle pole body component Spc42p Caudo_TAP PF02413.12 EIE78332.1 - 0.024 14.8 0.8 0.034 14.3 0.6 1.3 1 0 0 1 1 1 0 Caudovirales tail fibre assembly protein DUF4407 PF14362.1 EIE78332.1 - 0.085 11.8 1.8 0.12 11.2 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) IncA PF04156.9 EIE78332.1 - 0.14 11.7 5.3 0.14 11.7 3.3 1.4 1 1 0 1 1 1 0 IncA protein DUF948 PF06103.6 EIE78332.1 - 0.21 11.4 0.8 0.46 10.3 0.6 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF4613 PF15390.1 EIE78332.1 - 0.49 8.5 7.2 0.58 8.2 5.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Mto2_bdg PF12808.2 EIE78332.1 - 1.7 8.8 9.5 0.24 11.5 3.1 2.0 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region OmpH PF03938.9 EIE78332.1 - 2 8.3 10.1 3 7.7 7.0 1.5 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) bZIP_2 PF07716.10 EIE78332.1 - 5.2 6.9 12.0 0.11 12.3 2.5 2.4 2 1 1 3 3 3 0 Basic region leucine zipper SR-25 PF10500.4 EIE78332.1 - 7.1 6.0 19.8 11 5.3 13.7 1.3 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Chitin_synth_2 PF03142.10 EIE78333.1 - 3.4e-264 877.1 1.1 1.6e-263 874.9 0.7 1.9 1 1 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.1 EIE78333.1 - 2.6e-19 69.9 0.0 2.9e-17 63.2 0.0 2.2 1 1 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EIE78333.1 - 2.8e-19 69.6 1.3 9.7e-19 67.8 0.9 2.0 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.1 EIE78333.1 - 1.3e-05 24.6 0.0 0.0014 17.9 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EIE78333.1 - 2e-05 24.3 0.0 0.0012 18.5 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Epimerase PF01370.16 EIE78334.1 - 6.8e-26 91.1 0.1 1.2e-25 90.3 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EIE78334.1 - 8e-14 50.9 0.0 1.1e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EIE78334.1 - 4e-12 45.6 0.0 5.9e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EIE78334.1 - 7.4e-09 35.8 0.0 1.5e-08 34.9 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EIE78334.1 - 2.5e-05 24.2 0.0 9.3e-05 22.4 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_4 PF07993.7 EIE78334.1 - 5e-05 22.3 0.1 0.00089 18.2 0.1 2.3 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 EIE78334.1 - 6.2e-05 22.0 0.5 0.00015 20.7 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Saccharop_dh PF03435.13 EIE78334.1 - 0.0073 15.3 0.0 0.015 14.3 0.0 1.5 2 0 0 2 2 2 1 Saccharopine dehydrogenase KR PF08659.5 EIE78334.1 - 0.0078 15.9 0.0 0.018 14.6 0.0 1.6 2 0 0 2 2 2 1 KR domain RhoGEF PF00621.15 EIE78335.1 - 0.011 15.5 5.1 0.056 13.3 3.4 2.0 1 1 0 1 1 1 0 RhoGEF domain Aldo_ket_red PF00248.16 EIE78335.1 - 0.042 12.6 0.1 0.059 12.1 0.1 1.2 1 0 0 1 1 1 0 Aldo/keto reductase family DUF4503 PF14951.1 EIE78336.1 - 0.01 14.0 0.1 0.013 13.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4503) DUF1885 PF08968.5 EIE78336.1 - 0.046 13.4 0.7 0.066 12.8 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1885) DUF4358 PF14270.1 EIE78336.1 - 0.13 12.1 3.4 0.3 10.9 0.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4358) Adaptin_N PF01602.15 EIE78337.1 - 5.4e-118 394.6 9.1 7e-118 394.2 6.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 EIE78337.1 - 8.9e-18 64.3 0.0 2.4e-17 62.8 0.0 1.8 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 EIE78337.1 - 3.2e-15 56.4 0.0 6.5e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain FHA PF00498.21 EIE78338.1 - 1.4e-15 57.1 0.3 3.1e-15 56.0 0.2 1.6 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 EIE78338.1 - 1.1e-09 37.9 7.9 1.7e-09 37.3 5.5 1.3 1 0 0 1 1 1 1 Ring finger domain Rtf2 PF04641.7 EIE78338.1 - 4e-05 22.9 0.1 6.3e-05 22.3 0.1 1.3 1 0 0 1 1 1 1 Rtf2 RING-finger zf-C3HC4 PF00097.20 EIE78338.1 - 0.00012 21.7 6.7 0.0002 20.9 4.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EIE78338.1 - 0.00013 21.9 2.9 0.00029 20.8 2.0 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EIE78338.1 - 0.0023 17.5 4.2 0.0037 16.8 2.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIE78338.1 - 0.0036 16.9 6.7 0.0063 16.2 4.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EIE78338.1 - 0.0039 17.0 1.1 0.0067 16.2 0.8 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 EIE78338.1 - 0.015 15.2 9.5 0.025 14.5 6.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) BRX PF08381.6 EIE78338.1 - 0.038 13.0 0.1 0.079 12.0 0.0 1.4 1 0 0 1 1 1 0 Transcription factor regulating root and shoot growth via Pin3 DUF2405 PF10293.4 EIE78338.1 - 0.045 13.4 0.0 0.083 12.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2405) PHD PF00628.24 EIE78338.1 - 0.056 13.1 3.1 0.096 12.3 2.1 1.4 1 0 0 1 1 1 0 PHD-finger Metallophos PF00149.23 EIE78339.1 - 4.4e-10 39.2 0.2 1.1e-09 37.9 0.1 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EIE78339.1 - 4.5e-09 36.3 0.0 7.1e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF4448 PF14610.1 EIE78339.1 - 0.0098 15.3 0.3 0.015 14.7 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF4179 PF13786.1 EIE78339.1 - 0.013 15.6 1.3 0.028 14.6 0.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) DUF1191 PF06697.7 EIE78339.1 - 0.035 12.9 0.2 0.057 12.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) RskA PF10099.4 EIE78339.1 - 0.036 13.7 0.0 0.14 11.8 0.0 1.8 2 0 0 2 2 2 0 Anti-sigma-K factor rskA DUF929 PF06053.6 EIE78339.1 - 0.042 12.9 4.6 0.069 12.2 3.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF929) AA_permease_2 PF13520.1 EIE78339.1 - 0.049 12.1 0.1 0.071 11.6 0.1 1.1 1 0 0 1 1 1 0 Amino acid permease SRP9-21 PF05486.7 EIE78339.1 - 0.061 13.0 0.7 0.41 10.4 0.0 2.5 3 0 0 3 3 3 0 Signal recognition particle 9 kDa protein (SRP9) EphA2_TM PF14575.1 EIE78339.1 - 0.066 13.6 1.6 0.13 12.6 1.1 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Wzy_C PF04932.10 EIE78339.1 - 0.11 12.3 0.4 0.16 11.7 0.3 1.2 1 0 0 1 1 1 0 O-Antigen ligase COX6A PF02046.10 EIE78339.1 - 0.11 12.4 0.5 0.24 11.3 0.4 1.6 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIa tRNA_anti-like PF12869.2 EIE78339.1 - 0.15 11.5 2.5 0.27 10.7 1.7 1.3 1 0 0 1 1 1 0 tRNA_anti-like DUF1510 PF07423.6 EIE78339.1 - 0.22 10.8 2.4 0.32 10.3 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) NuiA PF07924.6 EIE78340.1 - 2.8e-05 24.0 2.9 0.00052 19.9 2.0 2.1 1 1 0 1 1 1 1 Nuclease A inhibitor-like protein DUF4393 PF14337.1 EIE78340.1 - 0.009 15.4 0.6 0.011 15.1 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4393) 6PGD PF00393.14 EIE78341.1 - 1.9e-137 457.2 0.0 2.3e-137 456.9 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EIE78341.1 - 2.7e-52 176.9 0.0 4e-52 176.3 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EIE78341.1 - 0.0059 16.6 0.1 3.2 7.8 0.0 3.1 3 0 0 3 3 3 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 EIE78341.1 - 0.015 15.6 0.0 0.03 14.7 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Thioredoxin_6 PF13848.1 EIE78342.1 - 9.9e-22 77.6 0.4 4.1e-12 46.2 0.0 3.1 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin PF00085.15 EIE78342.1 - 1.6e-10 40.6 0.3 0.0011 18.5 0.0 4.4 3 1 1 4 4 4 2 Thioredoxin Calsequestrin PF01216.12 EIE78342.1 - 6.3e-06 25.2 0.1 9.8e-06 24.5 0.0 1.2 1 0 0 1 1 1 1 Calsequestrin TIM PF00121.13 EIE78344.1 - 1.5e-93 312.4 0.1 1.6e-93 312.2 0.1 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase PilM PF07419.7 EIE78344.1 - 0.026 14.0 0.0 0.045 13.2 0.0 1.4 1 0 0 1 1 1 0 PilM CoA_binding PF02629.14 EIE78344.1 - 0.22 12.0 1.5 0.73 10.3 0.1 2.2 2 1 0 2 2 2 0 CoA binding domain Phosphoesterase PF04185.9 EIE78345.1 - 1.3e-12 47.5 0.9 2.4e-12 46.7 0.0 1.7 1 1 1 2 2 2 1 Phosphoesterase family Glyco_transf_49 PF13896.1 EIE78346.1 - 3.1e-44 151.3 2.1 1.3e-36 126.3 0.6 2.8 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glyco_tranf_2_2 PF10111.4 EIE78346.1 - 0.00029 20.0 0.1 0.00066 18.8 0.0 1.5 1 1 1 2 2 2 1 Glycosyltransferase like family 2 IlvN PF07991.7 EIE78347.1 - 1.4e-45 154.5 0.0 2.2e-45 153.9 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvC PF01450.14 EIE78347.1 - 3.1e-45 153.6 0.0 5.2e-45 152.9 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.10 EIE78347.1 - 0.0086 15.9 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EIE78347.1 - 0.01 16.2 0.0 0.024 15.0 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent AdoHcyase_NAD PF00670.16 EIE78347.1 - 0.077 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Profilin PF00235.14 EIE78348.1 - 2.5e-14 53.3 0.1 2.8e-14 53.2 0.1 1.0 1 0 0 1 1 1 1 Profilin TPT PF03151.11 EIE78349.1 - 9.9e-32 109.6 9.7 9.9e-32 109.6 6.8 1.7 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EIE78349.1 - 3.8e-05 22.7 15.3 6.7e-05 21.9 10.6 1.4 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EIE78349.1 - 4.5e-05 23.4 25.6 0.019 15.0 8.0 2.7 2 1 0 2 2 2 2 EamA-like transporter family MotA_ExbB PF01618.11 EIE78349.1 - 0.031 13.9 0.0 0.063 12.8 0.0 1.4 1 0 0 1 1 1 0 MotA/TolQ/ExbB proton channel family EmrE PF13536.1 EIE78349.1 - 0.065 13.4 15.6 0.083 13.0 2.0 2.5 3 0 0 3 3 3 0 Multidrug resistance efflux transporter AFOR_C PF01314.13 EIE78349.1 - 0.07 11.8 0.0 0.086 11.5 0.0 1.1 1 0 0 1 1 1 0 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 VirB3 PF05101.8 EIE78349.1 - 7 6.7 6.9 1.6 8.7 0.4 2.7 3 0 0 3 3 3 0 Type IV secretory pathway, VirB3-like protein AAA_33 PF13671.1 EIE78351.1 - 2.3e-16 59.9 0.0 3.2e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EIE78351.1 - 0.0069 16.7 0.0 0.012 15.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain L_protein_N PF15518.1 EIE78351.1 - 0.13 11.6 0.1 0.18 11.2 0.1 1.2 1 0 0 1 1 1 0 L protein N-terminus bZIP_1 PF00170.16 EIE78352.1 - 5.9e-09 35.7 11.6 5.9e-09 35.7 8.1 2.4 2 1 1 3 3 3 2 bZIP transcription factor bZIP_2 PF07716.10 EIE78352.1 - 2.3e-06 27.3 10.1 2.3e-06 27.3 7.0 2.9 2 1 1 3 3 3 2 Basic region leucine zipper PRCC PF10253.4 EIE78352.1 - 0.25 12.0 15.4 0.052 14.2 6.8 1.8 1 1 1 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting DUF3896 PF13035.1 EIE78352.1 - 0.6 10.2 14.1 1.2 9.2 0.2 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3896) FlaC_arch PF05377.6 EIE78352.1 - 0.72 9.7 8.9 0.62 9.9 1.1 3.0 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) RNase_HII PF01351.13 EIE78352.1 - 1.3 8.5 6.3 0.3 10.6 2.0 1.6 2 0 0 2 2 2 0 Ribonuclease HII Atg14 PF10186.4 EIE78352.1 - 4.5 6.1 24.2 2.5 6.9 9.9 2.2 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Jnk-SapK_ap_N PF09744.4 EIE78352.1 - 5.8 6.8 17.8 0.33 10.9 6.7 2.4 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 bZIP_Maf PF03131.12 EIE78352.1 - 6.1 7.2 19.3 0.28 11.4 7.9 2.5 2 1 0 2 2 2 0 bZIP Maf transcription factor YjgP_YjgQ PF03739.9 EIE78352.1 - 7.9 5.1 8.2 38 2.8 5.5 1.9 1 1 0 1 1 1 0 Predicted permease YjgP/YjgQ family zf-CCHC PF00098.18 EIE78353.1 - 0.0092 15.8 1.9 0.017 15.0 1.3 1.5 1 0 0 1 1 1 1 Zinc knuckle FAD_binding_2 PF00890.19 EIE78354.1 - 9.3e-81 271.7 0.0 1.1e-80 271.5 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EIE78354.1 - 9.7e-12 44.4 0.2 3.2e-06 26.3 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.9 EIE78354.1 - 4.9e-10 38.4 1.7 6.3e-06 24.9 0.2 2.5 3 0 0 3 3 3 2 HI0933-like protein FAD_oxidored PF12831.2 EIE78354.1 - 3.6e-09 36.2 0.7 1.2e-08 34.5 0.5 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 EIE78354.1 - 1.5e-08 33.9 5.9 8.3e-05 21.6 0.5 2.8 3 0 0 3 3 3 2 Glucose inhibited division protein A NAD_binding_8 PF13450.1 EIE78354.1 - 1.6e-08 34.4 0.6 3.1e-07 30.3 0.3 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EIE78354.1 - 3.8e-08 33.4 0.5 1.2e-06 28.6 0.1 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EIE78354.1 - 1.7e-07 31.5 0.0 1.1e-05 25.5 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EIE78354.1 - 0.00011 21.2 0.4 0.0036 16.2 0.2 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 EIE78354.1 - 0.00013 21.8 0.1 0.3 10.8 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 EIE78354.1 - 0.00041 19.5 0.2 0.0067 15.5 0.2 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 EIE78354.1 - 0.00048 20.4 1.0 0.003 17.9 0.3 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EIE78354.1 - 0.00051 19.2 0.5 0.032 13.3 0.0 2.5 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Thi4 PF01946.12 EIE78354.1 - 0.0069 15.5 0.3 0.0069 15.5 0.2 2.2 3 0 0 3 3 3 1 Thi4 family Trp_halogenase PF04820.9 EIE78354.1 - 0.086 11.4 2.4 0.19 10.3 0.3 2.0 2 0 0 2 2 2 0 Tryptophan halogenase Acyltransferase PF01553.16 EIE78355.1 - 1.5e-09 37.3 0.0 2e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Xan_ur_permease PF00860.15 EIE78356.1 - 4.2e-25 88.0 33.0 3.2e-24 85.1 22.9 2.0 1 1 0 1 1 1 1 Permease family DUF2834 PF11196.3 EIE78356.1 - 0.022 14.9 3.5 0.022 14.9 2.4 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2834) Wzy_C PF04932.10 EIE78356.1 - 0.77 9.5 18.1 0.045 13.5 0.9 3.4 3 0 0 3 3 3 0 O-Antigen ligase PetG PF02529.10 EIE78357.1 - 0.15 11.6 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit 5 Sulfate_transp PF00916.15 EIE78358.1 - 9.7e-63 211.7 13.0 9.7e-63 211.7 9.0 1.8 1 1 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EIE78358.1 - 2.6e-28 97.4 2.2 1.1e-27 95.4 1.5 2.2 1 0 0 1 1 1 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EIE78358.1 - 2.5e-22 78.4 0.0 4.3e-22 77.7 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 EIE78358.1 - 0.0039 17.1 0.0 0.011 15.7 0.0 1.7 1 0 0 1 1 1 1 STAS domain CCDC84 PF14968.1 EIE78359.1 - 0.57 9.6 4.8 0.71 9.3 3.4 1.2 1 0 0 1 1 1 0 Coiled coil protein 84 Suf PF05843.9 EIE78359.1 - 2.5 7.7 10.0 2.8 7.6 6.9 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Zip PF02535.17 EIE78360.1 - 1.3e-48 165.6 13.0 1.6e-48 165.3 9.0 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter HupE_UreJ PF04955.7 EIE78360.1 - 0.0017 17.7 0.8 0.0017 17.7 0.6 3.0 3 1 1 4 4 4 1 HupE / UreJ protein AAA_17 PF13207.1 EIE78361.1 - 5.6e-10 40.1 0.0 5.8e-10 40.0 0.0 1.0 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EIE78361.1 - 7.8e-08 32.6 0.1 8.5e-08 32.5 0.1 1.0 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EIE78361.1 - 6e-05 23.0 0.1 6.3e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EIE78361.1 - 0.00014 22.0 0.0 0.00015 21.9 0.0 1.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EIE78361.1 - 0.00015 21.4 0.1 0.00017 21.2 0.1 1.2 1 0 0 1 1 1 1 Part of AAA domain NTPase_1 PF03266.10 EIE78361.1 - 0.00023 20.8 0.2 0.00024 20.8 0.1 1.0 1 0 0 1 1 1 1 NTPase ADK PF00406.17 EIE78361.1 - 0.00028 20.7 0.0 0.00029 20.7 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_33 PF13671.1 EIE78361.1 - 0.00051 19.9 0.0 0.00054 19.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EIE78361.1 - 0.0015 17.6 0.0 0.0016 17.5 0.0 1.1 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.1 EIE78361.1 - 0.0018 18.2 0.0 0.0018 18.2 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 EIE78361.1 - 0.0025 16.9 0.0 0.0025 16.9 0.0 1.1 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus T2SE PF00437.15 EIE78361.1 - 0.0056 15.6 0.7 0.0062 15.4 0.5 1.1 1 0 0 1 1 1 1 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 EIE78361.1 - 0.0059 16.1 0.1 0.0063 16.0 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_22 PF13401.1 EIE78361.1 - 0.0064 16.6 0.0 0.0064 16.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 EIE78361.1 - 0.0067 16.1 0.1 0.0067 16.1 0.1 1.1 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.9 EIE78361.1 - 0.011 15.4 0.0 0.012 15.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) KaiC PF06745.8 EIE78361.1 - 0.013 14.6 0.1 0.013 14.6 0.0 1.2 1 0 0 1 1 1 0 KaiC AAA_10 PF12846.2 EIE78361.1 - 0.014 14.8 0.0 0.014 14.8 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain Phage_pRha PF09669.5 EIE78361.1 - 0.02 15.2 0.0 0.025 14.9 0.0 1.2 1 0 0 1 1 1 0 Phage regulatory protein Rha (Phage_pRha) KTI12 PF08433.5 EIE78361.1 - 0.021 14.0 0.0 0.021 14.0 0.0 1.1 1 0 0 1 1 1 0 Chromatin associated protein KTI12 RNA_helicase PF00910.17 EIE78361.1 - 0.021 15.0 0.0 0.024 14.7 0.0 1.1 1 0 0 1 1 1 0 RNA helicase Cytidylate_kin2 PF13189.1 EIE78361.1 - 0.022 14.6 0.0 0.023 14.5 0.0 1.1 1 0 0 1 1 1 0 Cytidylate kinase-like family AAA_30 PF13604.1 EIE78361.1 - 0.023 14.2 0.0 0.023 14.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.17 EIE78361.1 - 0.025 14.0 0.0 0.027 13.9 0.0 1.1 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_3 PF07726.6 EIE78361.1 - 0.03 13.9 0.0 0.035 13.7 0.0 1.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 EIE78361.1 - 0.037 13.1 0.0 0.042 13.0 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI SKI PF01202.17 EIE78361.1 - 0.04 13.7 0.1 0.054 13.3 0.1 1.4 1 1 0 1 1 1 0 Shikimate kinase Mur_ligase_M PF08245.7 EIE78361.1 - 0.04 13.9 0.4 0.04 13.9 0.3 1.1 1 0 0 1 1 1 0 Mur ligase middle domain Torsin PF06309.6 EIE78361.1 - 0.057 13.3 0.0 0.067 13.0 0.0 1.1 1 0 0 1 1 1 0 Torsin TrwB_AAD_bind PF10412.4 EIE78361.1 - 0.067 11.8 0.1 0.073 11.6 0.1 1.1 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Peptidase_M13 PF01431.16 EIE78361.1 - 0.072 12.2 0.0 0.076 12.1 0.0 1.1 1 0 0 1 1 1 0 Peptidase family M13 PRK PF00485.13 EIE78361.1 - 0.087 12.3 0.0 0.091 12.3 0.0 1.1 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family DUF2075 PF09848.4 EIE78361.1 - 0.12 11.3 1.5 0.14 11.0 1.0 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_29 PF13555.1 EIE78361.1 - 0.12 11.9 0.1 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain PhoH PF02562.11 EIE78361.1 - 0.12 11.5 0.0 0.12 11.5 0.0 1.0 1 0 0 1 1 1 0 PhoH-like protein ABC_tran PF00005.22 EIE78361.1 - 0.13 12.5 0.0 0.15 12.3 0.0 1.1 1 0 0 1 1 1 0 ABC transporter AAA_24 PF13479.1 EIE78361.1 - 0.32 10.5 1.8 0.52 9.8 1.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.1 EIE78361.1 - 0.38 10.3 2.6 0.32 10.5 0.7 1.6 1 1 1 2 2 2 0 AAA domain TPP_enzyme_N PF02776.13 EIE78362.1 - 3e-59 199.3 0.1 2.6e-58 196.3 0.0 2.5 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EIE78362.1 - 2.7e-53 179.6 0.2 1.2e-50 171.0 0.1 3.5 3 1 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EIE78362.1 - 6.5e-38 129.5 0.6 3.3e-37 127.3 0.1 2.3 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain CO_dh PF02552.11 EIE78362.1 - 0.025 14.1 0.2 0.057 12.9 0.1 1.5 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit Transpep_BrtH PF14399.1 EIE78362.1 - 0.11 11.7 0.1 0.27 10.4 0.0 1.6 2 0 0 2 2 2 0 NlpC/p60-like transpeptidase Iso_dh PF00180.15 EIE78363.1 - 1.7e-125 418.6 0.0 2e-125 418.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Auxin_repressed PF05564.7 EIE78363.1 - 0.074 13.6 0.0 0.15 12.6 0.0 1.5 1 0 0 1 1 1 0 Dormancy/auxin associated protein Methyltransf_16 PF10294.4 EIE78364.1 - 4.1e-25 88.2 0.9 7e-25 87.4 0.7 1.3 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 EIE78364.1 - 0.0003 20.2 0.0 0.00037 19.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.11 EIE78364.1 - 0.012 15.1 0.0 0.017 14.7 0.0 1.1 1 0 0 1 1 1 0 Met-10+ like-protein MethyltransfD12 PF02086.10 EIE78364.1 - 0.12 11.8 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase Vps26 PF03643.10 EIE78365.1 - 5.6e-111 369.7 4.9 6.7e-111 369.4 3.4 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 eIF_4EBP PF05456.6 EIE78366.1 - 8.6e-11 41.5 0.1 1e-10 41.2 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) ATP_Ca_trans_C PF12424.3 EIE78366.1 - 0.047 14.0 0.0 0.069 13.5 0.0 1.2 1 0 0 1 1 1 0 Plasma membrane calcium transporter ATPase C terminal SH3_1 PF00018.23 EIE78367.1 - 6.5e-17 60.6 1.4 1.4e-16 59.6 0.3 1.9 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 EIE78367.1 - 9.2e-15 53.8 0.1 1.5e-14 53.1 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EIE78367.1 - 4.8e-13 48.4 0.2 7.9e-13 47.7 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain RRM_1 PF00076.17 EIE78368.1 - 2.3e-90 296.2 1.8 5.5e-23 80.3 0.1 4.5 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE78368.1 - 3.7e-64 212.6 0.6 2.6e-16 59.3 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE78368.1 - 1.1e-45 153.2 0.1 2.8e-11 43.0 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 EIE78368.1 - 3.4e-05 23.4 0.5 0.0001 21.9 0.0 2.2 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain OB_RNB PF08206.6 EIE78368.1 - 0.00075 18.9 1.9 2.1 7.9 0.0 3.7 3 1 0 3 3 3 2 Ribonuclease B OB domain Nup35_RRM_2 PF14605.1 EIE78368.1 - 0.0045 16.7 0.1 25 4.7 0.0 4.0 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 EIE78368.1 - 0.0059 16.3 5.0 4.5 7.1 0.3 4.2 2 1 2 4 4 4 2 Limkain b1 YflT PF11181.3 EIE78368.1 - 0.035 14.2 2.5 0.34 11.0 1.4 2.4 2 0 0 2 2 2 0 Heat induced stress protein YflT CbiG_mid PF11761.3 EIE78368.1 - 0.052 13.7 0.0 2.4 8.4 0.0 2.7 3 0 0 3 3 3 0 Cobalamin biosynthesis central region DUF4523 PF15023.1 EIE78368.1 - 0.079 12.4 0.0 20 4.6 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4523) Lyase_1 PF00206.15 EIE78369.1 - 1.6e-120 402.0 0.0 2e-120 401.7 0.0 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 EIE78369.1 - 2.8e-27 94.5 0.0 5.6e-27 93.5 0.0 1.6 1 0 0 1 1 1 1 Fumarase C C-terminus B3_4 PF03483.12 EIE78369.1 - 0.051 13.0 0.0 0.09 12.2 0.0 1.3 1 0 0 1 1 1 0 B3/4 domain Ribosomal_L31e PF01198.14 EIE78370.1 - 2.1e-31 107.3 3.1 2.6e-31 107.1 2.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e zf-C2H2 PF00096.21 EIE78371.1 - 8e-18 63.6 40.2 7.2e-05 22.8 2.3 4.9 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIE78371.1 - 5.4e-14 51.4 35.9 0.00065 19.8 1.5 4.9 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EIE78371.1 - 2.6e-10 40.0 34.9 3.5e-05 23.8 3.4 5.6 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_6 PF13912.1 EIE78371.1 - 0.015 15.1 0.7 0.015 15.1 0.5 4.0 3 0 0 3 3 3 0 C2H2-type zinc finger FYDLN_acid PF09538.5 EIE78371.1 - 0.024 15.2 3.1 3.7 8.1 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) CCAP PF11105.3 EIE78371.1 - 0.69 9.6 6.2 1.3 8.7 0.2 3.0 2 1 1 3 3 3 0 Arthropod cardioacceleratory peptide 2a Ogr_Delta PF04606.7 EIE78371.1 - 0.7 9.5 7.1 12 5.6 1.5 3.9 2 2 1 3 3 3 0 Ogr/Delta-like zinc finger RskA PF10099.4 EIE78371.1 - 0.94 9.1 8.8 0.91 9.2 0.4 2.7 3 0 0 3 3 3 0 Anti-sigma-K factor rskA zf-C2H2_jaz PF12171.3 EIE78371.1 - 7 6.9 22.1 1.2 9.3 0.9 4.4 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding CDP-OH_P_transf PF01066.16 EIE78372.1 - 2.1e-12 47.2 13.5 2.1e-12 47.2 9.4 3.6 2 1 1 3 3 3 1 CDP-alcohol phosphatidyltransferase zf-RVT PF13966.1 EIE78373.1 - 9.3e-05 22.6 1.8 0.00042 20.5 0.4 2.5 3 1 0 3 3 3 1 zinc-binding in reverse transcriptase DUF1499 PF07386.6 EIE78375.1 - 0.11 12.6 0.2 0.12 12.5 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1499) Methyltrn_RNA_4 PF09936.4 EIE78375.1 - 0.15 11.5 0.3 0.16 11.4 0.2 1.0 1 0 0 1 1 1 0 SAM-dependent RNA methyltransferase Mlp PF03304.8 EIE78377.1 - 0.017 15.1 1.0 0.017 15.1 0.7 2.1 2 1 0 2 2 2 0 Mlp lipoprotein family DUF792 PF05632.6 EIE78378.1 - 0.00024 20.5 0.0 0.00028 20.2 0.0 1.0 1 0 0 1 1 1 1 Borrelia burgdorferi protein of unknown function (DUF792) PH_5 PF15405.1 EIE78380.1 - 4.2e-35 120.6 0.3 9.7e-35 119.4 0.2 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 EIE78380.1 - 2.1e-32 112.4 0.6 3.9e-32 111.5 0.4 1.4 1 0 0 1 1 1 1 RhoGEF domain CNH PF00780.17 EIE78380.1 - 1.2e-22 80.6 0.1 2.2e-22 79.8 0.0 1.3 1 0 0 1 1 1 1 CNH domain PH PF00169.24 EIE78380.1 - 9.8e-06 25.7 0.3 0.0001 22.4 0.1 2.7 2 0 0 2 2 2 1 PH domain RNA_pol_Rpb1_7 PF04990.7 EIE78380.1 - 0.042 13.5 0.1 0.086 12.5 0.1 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 7 PPR_2 PF13041.1 EIE78381.1 - 1.5e-57 191.3 19.7 1.1e-08 34.8 0.9 15.3 8 3 10 18 18 18 8 PPR repeat family PPR_3 PF13812.1 EIE78381.1 - 4.6e-45 148.1 10.7 0.00072 19.6 0.0 18.4 20 0 0 20 20 20 8 Pentatricopeptide repeat domain PPR PF01535.15 EIE78381.1 - 9e-41 135.0 23.5 1e-05 25.1 0.0 16.8 19 0 0 19 19 19 8 PPR repeat PPR_1 PF12854.2 EIE78381.1 - 2e-37 126.3 2.1 6e-05 22.4 0.0 12.2 14 0 0 14 14 14 6 PPR repeat TPR_16 PF13432.1 EIE78381.1 - 2.9e-07 30.9 0.0 0.78 10.4 0.0 6.5 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_14 PF13428.1 EIE78381.1 - 2.4e-06 27.6 0.0 17 6.3 0.0 8.4 10 0 0 10 10 8 0 Tetratricopeptide repeat TPR_19 PF14559.1 EIE78381.1 - 4.6e-05 23.6 0.1 14 6.0 0.0 6.1 4 2 2 6 6 6 0 Tetratricopeptide repeat ATP13 PF12921.2 EIE78381.1 - 0.00085 18.6 0.8 43 3.4 0.0 5.8 6 1 1 7 7 7 0 Mitochondrial ATPase expression TPR_2 PF07719.12 EIE78381.1 - 0.032 14.1 0.9 0.61 10.1 0.0 3.7 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 EIE78381.1 - 0.045 13.3 0.8 1.3 8.7 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 EIE78381.1 - 0.051 13.3 3.3 5.9 6.9 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 EIE78381.1 - 0.064 13.7 0.1 1.5e+02 3.2 0.0 5.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Acyltransferase PF01553.16 EIE78382.1 - 1.1e-05 24.9 0.0 3e-05 23.4 0.0 1.8 2 0 0 2 2 2 1 Acyltransferase Actin PF00022.14 EIE78383.1 - 3.6e-10 38.8 0.0 3.7e-10 38.7 0.0 1.0 1 0 0 1 1 1 1 Actin BBS2_N PF14781.1 EIE78383.1 - 0.13 11.9 0.2 0.13 11.9 0.1 1.1 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, N-terminal Asp PF00026.18 EIE78384.1 - 1.9e-35 122.6 21.0 1.5e-17 63.8 0.5 2.3 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIE78384.1 - 2.8e-08 33.8 1.9 2.8e-08 33.8 1.3 2.4 1 1 1 2 2 2 1 Xylanase inhibitor N-terminal Mucin PF01456.12 EIE78384.1 - 0.56 9.9 22.9 1.4 8.7 15.8 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF1190 PF06693.6 EIE78384.1 - 6.6 6.7 18.7 1.8 8.5 9.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1190) CENP-B_N PF04218.8 EIE78385.1 - 0.018 14.4 0.0 0.031 13.7 0.0 1.5 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain PrgU PF09627.5 EIE78385.1 - 0.031 13.8 0.8 0.27 10.8 0.6 2.0 1 1 0 1 1 1 0 PrgU-like protein tRNA_synt_1c_R1 PF04558.10 EIE78385.1 - 0.032 13.7 0.2 0.046 13.2 0.2 1.3 1 0 0 1 1 1 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 KSR1-SAM PF13543.1 EIE78385.1 - 0.076 12.8 0.5 0.17 11.6 0.1 1.7 2 0 0 2 2 2 0 SAM like domain present in kinase suppressor RAS 1 Myc_N PF01056.13 EIE78386.1 - 0.059 12.5 2.0 0.068 12.3 1.4 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Bro-N PF02498.12 EIE78387.1 - 0.095 12.9 0.0 0.1 12.8 0.0 1.1 1 0 0 1 1 1 0 BRO family, N-terminal domain Cpn60_TCP1 PF00118.19 EIE78388.1 - 8.8e-136 453.3 8.8 1e-135 453.0 6.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF3271 PF11675.3 EIE78388.1 - 0.046 12.8 0.2 0.087 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3271) Prefoldin PF02996.12 EIE78389.1 - 1.5e-29 102.0 4.6 2.2e-29 101.5 3.2 1.2 1 0 0 1 1 1 1 Prefoldin subunit MMgT PF10270.4 EIE78389.1 - 4.6e-05 23.8 0.5 0.00016 22.0 0.0 2.1 3 0 0 3 3 3 1 Membrane magnesium transporter DUF4358 PF14270.1 EIE78389.1 - 0.096 12.5 0.6 0.19 11.6 0.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4358) Prefoldin_2 PF01920.15 EIE78389.1 - 1.4 8.7 7.4 1.8 8.3 0.3 2.3 2 0 0 2 2 2 0 Prefoldin subunit MOR2-PAG1_mid PF14228.1 EIE78390.1 - 1e-71 241.9 17.0 2.7e-31 108.0 0.5 3.5 2 1 1 3 3 3 3 Cell morphogenesis central region MOR2-PAG1_C PF14225.1 EIE78390.1 - 2.1e-53 181.7 1.8 1.4e-52 179.0 0.2 2.9 3 0 0 3 3 3 1 Cell morphogenesis C-terminal MOR2-PAG1_N PF14222.1 EIE78390.1 - 3.9e-13 48.9 0.0 8.8e-13 47.7 0.0 1.6 1 0 0 1 1 1 1 Cell morphogenesis N-terminal HEAT PF02985.17 EIE78390.1 - 0.0086 16.0 1.0 27 5.1 0.0 5.2 5 0 0 5 5 5 0 HEAT repeat HEAT_2 PF13646.1 EIE78390.1 - 0.013 15.8 0.1 21 5.4 0.0 4.6 5 0 0 5 5 5 0 HEAT repeats Toxin_5 PF05294.8 EIE78390.1 - 8.3 6.7 6.0 7.8 6.8 0.5 2.4 2 0 0 2 2 2 0 Scorpion short toxin zf-RVT PF13966.1 EIE78391.1 - 3.2e-05 24.1 0.3 6e-05 23.2 0.2 1.4 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Mto2_bdg PF12808.2 EIE78393.1 - 0.035 14.2 1.5 2.8 8.0 0.3 2.5 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region rve PF00665.21 EIE78394.1 - 1.5e-23 83.1 0.0 1.9e-22 79.5 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 EIE78394.1 - 8.8e-17 61.1 0.0 1.7e-16 60.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE78394.1 - 2.6e-11 43.0 0.2 5.3e-11 42.0 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.1 EIE78394.1 - 2.9e-06 27.6 0.0 1.2e-05 25.7 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.1 EIE78394.1 - 0.0009 19.0 0.0 0.0018 18.0 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.5 EIE78394.1 - 0.0078 15.6 0.1 0.024 14.0 0.0 1.9 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger RVT_1 PF00078.22 EIE78396.1 - 4.7e-30 104.5 0.2 9.4e-30 103.5 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease PF09668.5 EIE78396.1 - 1e-08 34.7 0.0 1.9e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 EIE78396.1 - 3e-05 24.4 0.0 7.2e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 EIE78396.1 - 4.2e-05 23.3 0.0 0.00016 21.4 0.0 2.1 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.6 EIE78396.1 - 0.0052 16.7 0.0 0.027 14.3 0.0 2.0 1 1 0 2 2 2 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EIE78396.1 - 0.026 14.3 0.0 0.059 13.2 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease LpxC PF03331.8 EIE78397.1 - 0.025 13.5 0.3 0.05 12.5 0.1 1.5 1 1 0 1 1 1 0 UDP-3-O-acyl N-acetylglycosamine deacetylase Imm15 PF15590.1 EIE78397.1 - 0.09 11.8 1.6 0.17 11.0 0.1 2.2 3 0 0 3 3 3 0 Immunity protein 15 AAA_23 PF13476.1 EIE78397.1 - 1.5 9.1 9.4 2.7 8.2 6.5 1.5 1 1 0 1 1 1 0 AAA domain DUF2779 PF11074.3 EIE78397.1 - 5.7 6.9 8.3 27 4.7 2.9 2.5 2 1 1 3 3 3 0 Domain of unknown function(DUF2779) DUF1759 PF03564.10 EIE78398.1 - 0.00017 21.4 0.4 0.0002 21.2 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) Sigma70_r1_1 PF03979.9 EIE78398.1 - 0.05 13.5 0.2 0.089 12.7 0.2 1.3 1 0 0 1 1 1 0 Sigma-70 factor, region 1.1 Rabaptin PF03528.10 EIE78398.1 - 0.17 11.8 1.2 2.1 8.3 0.1 2.1 1 1 1 2 2 2 0 Rabaptin rve PF00665.21 EIE78399.1 - 1.8e-22 79.6 0.0 4.5e-22 78.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE78399.1 - 1.5e-15 57.1 0.1 3.2e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.12 EIE78399.1 - 8.2e-09 35.4 0.1 2.3e-08 34.0 0.1 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein Chromo PF00385.19 EIE78399.1 - 4.2e-08 32.7 0.1 9.7e-08 31.5 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 EIE78399.1 - 0.00047 19.5 1.6 0.0015 17.9 1.1 1.9 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Asp_protease PF09668.5 EIE78400.1 - 3.4e-10 39.5 0.0 5.4e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 EIE78400.1 - 5.4e-08 33.2 0.0 1.5e-07 31.7 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 EIE78400.1 - 3.5e-06 26.8 0.3 1.9e-05 24.4 0.0 2.4 2 1 1 3 3 3 1 Retroviral aspartyl protease RVP_2 PF08284.6 EIE78400.1 - 5.6e-06 26.3 0.0 1.4e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EIE78400.1 - 0.00033 20.4 0.1 0.00062 19.5 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease NOA36 PF06524.7 EIE78400.1 - 2.5 7.2 7.0 5.2 6.2 4.8 1.5 1 0 0 1 1 1 0 NOA36 protein DUF1759 PF03564.10 EIE78401.1 - 0.00021 21.1 0.4 0.00021 21.1 0.3 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1759) MCPVI PF02993.9 EIE78402.1 - 0.086 12.9 3.6 0.11 12.6 2.5 1.1 1 0 0 1 1 1 0 Minor capsid protein VI RVT_1 PF00078.22 EIE78403.1 - 4e-21 75.3 0.1 1.1e-20 73.9 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.1 EIE78403.1 - 4.2e-07 30.1 5.4 2e-06 27.9 3.8 2.2 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Exo_endo_phos PF03372.18 EIE78403.1 - 0.0012 18.8 0.5 0.0026 17.7 0.4 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EIE78403.1 - 0.0026 17.3 0.5 0.0065 16.0 0.3 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase zf-CCHC PF00098.18 EIE78404.1 - 1.8e-10 40.2 8.0 1.2e-05 24.9 0.3 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 EIE78404.1 - 0.0031 17.1 6.6 0.047 13.3 0.3 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.1 EIE78404.1 - 1.3 8.5 4.5 0.75 9.3 0.3 2.3 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC_6 PF15288.1 EIE78404.1 - 1.7 8.3 8.1 0.075 12.7 1.1 2.1 1 1 1 2 2 2 0 Zinc knuckle HTH_38 PF13936.1 EIE78405.1 - 2.1e-06 27.1 0.0 3.4e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.1 EIE78405.1 - 0.00013 21.5 0.0 0.00026 20.5 0.0 1.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_7 PF02796.10 EIE78405.1 - 0.00015 21.5 0.1 0.013 15.3 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_28 PF13518.1 EIE78405.1 - 0.00031 20.6 0.0 0.00043 20.2 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.7 EIE78405.1 - 0.0015 17.9 0.0 0.0026 17.2 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_Tnp_4 PF13613.1 EIE78405.1 - 0.0043 16.5 0.1 0.0071 15.8 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease CPSase_L_D3 PF02787.14 EIE78405.1 - 0.0077 15.9 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain HTH_29 PF13551.1 EIE78405.1 - 0.0085 16.2 0.0 0.012 15.7 0.0 1.2 1 0 0 1 1 1 1 Winged helix-turn helix DUF2857 PF11198.3 EIE78405.1 - 0.0099 15.4 0.0 0.012 15.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2857) UPF0122 PF04297.9 EIE78405.1 - 0.017 15.1 0.0 0.035 14.1 0.0 1.4 1 0 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like Sigma70_r4 PF04545.11 EIE78405.1 - 0.037 13.3 0.0 0.08 12.2 0.0 1.5 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_32 PF13565.1 EIE78405.1 - 0.13 13.1 0.2 10 6.9 0.0 2.1 2 0 0 2 2 2 0 Homeodomain-like domain HTH_40 PF14493.1 EIE78405.1 - 0.13 12.4 0.0 0.37 11.0 0.0 1.6 2 0 0 2 2 2 0 Helix-turn-helix domain Phage_XkdX PF09693.5 EIE78406.1 - 0.031 13.8 0.0 0.051 13.1 0.0 1.3 1 0 0 1 1 1 0 Phage uncharacterised protein (Phage_XkdX) DDE_3 PF13358.1 EIE78407.1 - 1.7e-18 66.7 0.0 2.8e-18 66.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE78407.1 - 3.4e-07 30.2 0.4 8.4e-07 28.9 0.1 1.9 2 0 0 2 2 2 1 Transposase GTP_EFTU_D2 PF03144.20 EIE78407.1 - 0.021 14.9 0.1 0.12 12.4 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu domain 2 DDE_3 PF13358.1 EIE78408.1 - 2.3e-19 69.5 0.5 5.6e-19 68.3 0.3 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE78408.1 - 3.7e-10 39.7 0.9 3.7e-10 39.7 0.6 2.2 2 0 0 2 2 2 1 Transposase HTH_38 PF13936.1 EIE78408.1 - 0.0004 19.8 0.1 0.0011 18.4 0.1 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain MarR PF01047.17 EIE78408.1 - 0.0051 16.4 0.1 0.23 11.1 0.0 2.7 3 0 0 3 3 3 1 MarR family HTH_23 PF13384.1 EIE78408.1 - 0.0054 16.3 0.6 0.019 14.6 0.0 2.1 2 0 0 2 2 2 1 Homeodomain-like domain Sigma54_DBD PF04552.8 EIE78408.1 - 0.064 12.7 0.1 0.22 11.0 0.0 1.9 1 1 1 2 2 2 0 Sigma-54, DNA binding domain TrmB PF01978.14 EIE78408.1 - 0.082 12.6 0.8 1.3 8.7 0.0 2.8 2 1 1 3 3 3 0 Sugar-specific transcriptional regulator TrmB LacI PF00356.16 EIE78408.1 - 0.17 11.5 0.4 0.6 9.7 0.0 2.1 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family HTH_32 PF13565.1 EIE78408.1 - 0.8 10.5 4.7 41 5.0 0.0 3.7 3 2 1 4 4 4 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.13 EIE78409.1 - 4e-06 26.7 0.1 8e-06 25.8 0.1 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.1 EIE78409.1 - 0.00041 20.1 0.0 0.00059 19.6 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease RVT_1 PF00078.22 EIE78410.1 - 8.1e-05 22.0 0.3 0.00013 21.4 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PdxA PF04166.7 EIE78410.1 - 0.078 12.1 0.0 0.089 11.9 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal phosphate biosynthetic protein PdxA HTH_30 PF13556.1 EIE78411.1 - 0.047 13.2 0.0 0.11 12.1 0.0 1.6 1 1 1 2 2 2 0 PucR C-terminal helix-turn-helix domain zf-CCHC PF00098.18 EIE78414.1 - 7.7e-10 38.2 9.1 4e-05 23.3 0.7 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 EIE78414.1 - 0.014 15.0 6.9 1.2 8.8 0.2 2.5 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.1 EIE78414.1 - 0.015 14.8 0.9 0.015 14.8 0.6 3.0 2 1 1 3 3 3 0 Zinc knuckle zf-CCHC_6 PF15288.1 EIE78414.1 - 0.056 13.1 1.8 0.056 13.1 1.2 2.3 1 1 1 2 2 2 0 Zinc knuckle Zn_ribbon_2 PF12674.2 EIE78414.1 - 0.66 10.3 3.1 4 7.8 1.9 2.0 1 1 1 2 2 2 0 Putative zinc ribbon domain zf-CCHC_3 PF13917.1 EIE78414.1 - 0.92 9.2 6.6 1.2 8.9 0.4 2.5 1 1 1 2 2 2 0 Zinc knuckle Kisspeptin PF15152.1 EIE78414.1 - 1.1 9.9 5.8 4.8 7.9 0.5 2.4 2 0 0 2 2 2 0 Kisspeptin Elf1 PF05129.8 EIE78414.1 - 4.1 7.1 6.8 12 5.6 2.5 2.5 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like zf-RVT PF13966.1 EIE78415.1 - 7.2e-10 39.0 1.5 1.5e-09 37.9 1.0 1.6 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase zf-CCHC PF00098.18 EIE78416.1 - 4.9e-05 23.0 11.2 0.0039 17.0 0.9 2.3 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 EIE78416.1 - 0.0047 16.5 5.7 0.0089 15.6 0.3 2.4 2 0 0 2 2 2 1 Zinc knuckle RRM_1 PF00076.17 EIE78416.1 - 0.057 13.0 0.0 0.17 11.5 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC_3 PF13917.1 EIE78416.1 - 3.7 7.3 8.2 2.3 7.9 0.1 2.4 1 1 1 2 2 2 0 Zinc knuckle Zn_ribbon_2 PF12674.2 EIE78416.1 - 7.3 7.0 7.4 34 4.8 0.6 2.6 1 1 1 2 2 2 0 Putative zinc ribbon domain RVT_1 PF00078.22 EIE78417.1 - 9.8e-39 132.9 0.0 2.1e-38 131.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_3 PF13358.1 EIE78418.1 - 1.5e-17 63.7 0.1 3.5e-17 62.5 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE78418.1 - 1.4e-07 31.4 0.5 5.9e-07 29.4 0.5 2.0 2 1 0 2 2 2 1 Transposase zf-RVT PF13966.1 EIE78419.1 - 0.002 18.4 0.2 0.0037 17.5 0.1 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Dam PF05869.6 EIE78420.1 - 0.00022 20.6 0.0 0.00034 20.0 0.0 1.3 1 0 0 1 1 1 1 DNA N-6-adenine-methyltransferase (Dam) RNase_H PF00075.19 EIE78420.1 - 0.00085 19.6 0.2 0.0014 19.0 0.2 1.3 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 EIE78420.1 - 0.047 13.4 0.0 0.069 12.9 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase-like PCIF1_WW PF12237.3 EIE78420.1 - 0.098 11.9 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Phosphorylated CTD interacting factor 1 WW domain Kelch_3 PF13415.1 EIE78421.1 - 2.3e-18 65.8 8.3 4.4e-05 23.5 0.0 7.2 6 2 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.1 EIE78421.1 - 3.3e-17 61.9 4.5 1.7e-06 27.6 0.1 5.6 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.1 EIE78421.1 - 8.6e-12 44.7 2.1 6.4e-05 22.8 0.0 4.9 5 0 0 5 5 5 2 Kelch motif Kelch_6 PF13964.1 EIE78421.1 - 2.2e-10 40.2 8.8 7.4e-05 22.7 0.0 6.0 5 2 0 5 5 5 3 Kelch motif Kelch_1 PF01344.20 EIE78421.1 - 4.8e-06 26.0 9.3 0.00013 21.3 0.1 5.0 4 1 0 4 4 4 1 Kelch motif Kelch_2 PF07646.10 EIE78421.1 - 0.00012 21.6 15.3 0.00013 21.5 0.1 5.2 5 1 0 5 5 5 1 Kelch motif Delta_lysin PF05372.6 EIE78422.1 - 0.074 12.4 0.8 0.074 12.4 0.6 2.0 2 0 0 2 2 2 0 Delta lysin family Zn_clus PF00172.13 EIE78423.1 - 6.6e-11 41.9 10.9 1.3e-10 41.0 7.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EMP24_GP25L PF01105.19 EIE78423.1 - 0.016 14.9 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Aminotran_5 PF00266.14 EIE78424.1 - 5.6e-11 41.7 0.0 6.1e-11 41.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V E1-E2_ATPase PF00122.15 EIE78425.1 - 2.9e-55 186.8 1.8 2.9e-55 186.8 1.2 2.8 3 1 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EIE78425.1 - 2.2e-45 154.4 10.0 2.2e-45 154.4 6.9 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EIE78425.1 - 2.4e-27 96.7 0.0 6.5e-27 95.3 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EIE78425.1 - 1.3e-20 73.1 0.0 3.1e-20 71.9 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EIE78425.1 - 1.4e-14 54.6 0.0 3.2e-14 53.5 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EIE78425.1 - 6.8e-10 38.2 0.2 2.3e-08 33.3 0.1 2.7 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EIE78425.1 - 3.7e-05 23.4 1.2 0.012 15.2 0.1 2.9 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase DUF3325 PF11804.3 EIE78425.1 - 0.19 11.6 0.0 0.19 11.6 0.0 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF3325) DUF4231 PF14015.1 EIE78425.1 - 0.71 9.8 0.0 0.71 9.8 0.0 3.5 5 0 0 5 5 5 0 Protein of unknown function (DUF4231) SNF2_N PF00176.18 EIE78426.1 - 2e-81 273.1 1.9 3.7e-81 272.2 1.3 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EIE78426.1 - 9.4e-15 54.2 0.0 1e-13 50.9 0.0 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EIE78426.1 - 2.6e-08 33.5 0.1 8e-08 31.9 0.1 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EIE78426.1 - 7e-05 22.7 0.7 7e-05 22.7 0.5 2.7 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit DZR PF12773.2 EIE78426.1 - 0.054 13.3 2.6 0.079 12.7 0.9 2.0 2 0 0 2 2 2 0 Double zinc ribbon CENP-T PF15511.1 EIE78428.1 - 0.00064 19.0 18.3 0.022 14.0 0.6 2.1 2 0 0 2 2 2 2 Centromere kinetochore component CENP-T MoCF_biosynth PF00994.19 EIE78428.1 - 0.039 13.3 0.0 0.061 12.7 0.0 1.4 1 0 0 1 1 1 0 Probable molybdopterin binding domain UPF0561 PF10573.4 EIE78428.1 - 0.24 11.2 6.8 0.099 12.4 0.2 2.6 2 0 0 2 2 2 0 Uncharacterised protein family UPF0561 GDPD PF03009.12 EIE78429.1 - 1.4e-65 221.3 0.1 3.7e-65 219.9 0.0 1.7 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.2 EIE78429.1 - 4.1e-38 129.5 2.0 1.1e-16 60.8 0.0 4.4 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EIE78429.1 - 5.1e-25 85.9 2.5 1e-05 25.0 0.0 7.9 8 1 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.1 EIE78429.1 - 4.2e-23 80.8 2.5 6.1e-06 26.3 0.0 6.0 4 2 0 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 EIE78429.1 - 9.9e-23 80.0 0.8 7.4e-07 29.5 0.0 5.4 2 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIE78429.1 - 3.5e-20 70.0 4.0 0.05 13.8 0.1 8.5 7 1 1 8 8 8 5 Ankyrin repeat SPX PF03105.14 EIE78429.1 - 1.4e-16 61.1 9.0 1.7e-09 37.9 0.2 3.1 3 1 1 4 4 4 2 SPX domain Fer2 PF00111.22 EIE78430.1 - 1.9e-10 40.3 4.1 2.6e-10 39.8 2.8 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain PWI PF01480.12 EIE78431.1 - 0.092 12.8 0.6 0.092 12.8 0.4 1.9 2 0 0 2 2 2 0 PWI domain DUF572 PF04502.8 EIE78431.1 - 0.87 8.7 24.4 0.95 8.6 16.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) SpoVR PF04293.8 EIE78431.1 - 1.1 7.5 13.8 1.4 7.1 9.6 1.1 1 0 0 1 1 1 0 SpoVR like protein Band_3_cyto PF07565.8 EIE78431.1 - 3.2 7.2 9.4 3.7 6.9 6.5 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Atg14 PF10186.4 EIE78431.1 - 9.4 5.0 17.4 11 4.8 12.1 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF1052 PF06319.7 EIE78432.1 - 0.018 14.3 0.0 0.025 13.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1052) DUF869 PF05911.6 EIE78435.1 - 0.0085 14.3 0.5 0.0097 14.1 0.4 1.1 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) NDT80_PhoG PF05224.7 EIE78436.1 - 5.4e-39 134.1 0.0 1.1e-38 133.0 0.0 1.6 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family DUF1180 PF06679.7 EIE78436.1 - 1.4 8.7 0.0 1.4 8.7 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1180) Kinesin PF00225.18 EIE78438.1 - 1.8e-109 365.4 0.0 3.3e-109 364.6 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.3 EIE78438.1 - 8.4e-38 129.1 0.0 2.5e-37 127.6 0.0 1.9 1 0 0 1 1 1 1 Kinesin protein PH PF00169.24 EIE78438.1 - 1.3e-13 51.0 0.6 6.6e-13 48.7 0.1 2.5 2 0 0 2 2 2 1 PH domain KIF1B PF12423.3 EIE78438.1 - 7.8e-10 38.6 0.2 2.4e-09 37.0 0.2 1.9 1 0 0 1 1 1 1 Kinesin protein 1B FHA PF00498.21 EIE78438.1 - 8.5e-06 25.8 0.1 4.8e-05 23.3 0.0 2.4 3 0 0 3 3 3 1 FHA domain PH_11 PF15413.1 EIE78438.1 - 0.23 11.6 9.3 0.066 13.4 1.3 3.5 3 1 0 3 3 3 0 Pleckstrin homology domain MDM31_MDM32 PF08118.6 EIE78439.1 - 1.3e-90 304.2 0.2 1.6e-53 181.9 0.0 2.9 2 1 0 2 2 2 2 Yeast mitochondrial distribution and morphology (MDM) proteins zf-Di19 PF05605.7 EIE78440.1 - 0.05 13.7 0.6 0.093 12.8 0.4 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding DDE_3 PF13358.1 EIE78442.1 - 1.1e-30 106.2 0.0 1.8e-30 105.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.14 EIE78442.1 - 0.0004 19.5 0.9 0.051 12.7 0.1 2.3 2 0 0 2 2 2 2 DDE superfamily endonuclease HTH_32 PF13565.1 EIE78442.1 - 0.011 16.5 0.0 0.036 14.8 0.0 1.9 2 0 0 2 2 2 0 Homeodomain-like domain HTH_17 PF12728.2 EIE78442.1 - 0.013 15.6 0.0 0.036 14.3 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_22 PF13309.1 EIE78442.1 - 0.024 14.3 0.2 0.51 10.1 0.1 2.5 2 0 0 2 2 2 0 HTH domain HTH_Tnp_Tc3_2 PF01498.13 EIE78442.1 - 0.061 13.3 0.3 0.22 11.5 0.0 2.2 2 1 0 2 2 2 0 Transposase HTH_21 PF13276.1 EIE78442.1 - 0.099 12.6 0.0 0.32 11.0 0.0 1.9 1 0 0 1 1 1 0 HTH-like domain ApoO PF09769.4 EIE78443.1 - 3.7e-30 104.7 5.0 3e-27 95.2 0.1 2.5 1 1 1 2 2 2 2 Apolipoprotein O ApoLp-III PF07464.6 EIE78443.1 - 2e-06 27.8 8.1 1.5e-05 25.0 2.4 2.2 2 0 0 2 2 2 1 Apolipophorin-III precursor (apoLp-III) Apolipoprotein PF01442.13 EIE78443.1 - 2.9e-05 23.6 2.7 2.9e-05 23.6 1.8 1.9 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain PspA_IM30 PF04012.7 EIE78443.1 - 0.00013 21.4 2.1 0.00013 21.4 1.4 2.0 2 0 0 2 2 2 1 PspA/IM30 family Baculo_PEP_C PF04513.7 EIE78443.1 - 0.013 15.3 2.3 0.025 14.4 0.6 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FlgN PF05130.7 EIE78443.1 - 0.014 15.6 0.4 0.029 14.6 0.3 1.5 1 0 0 1 1 1 0 FlgN protein Prominin PF05478.6 EIE78443.1 - 0.018 12.5 3.4 0.023 12.2 1.1 1.8 2 0 0 2 2 2 0 Prominin CsbD PF05532.7 EIE78443.1 - 0.063 12.9 0.2 0.4 10.3 0.0 2.3 2 0 0 2 2 2 0 CsbD-like UPF0118 PF01594.11 EIE78443.1 - 0.09 11.7 0.2 0.18 10.7 0.1 1.5 1 1 1 2 2 2 0 Domain of unknown function DUF20 Fib_alpha PF08702.5 EIE78443.1 - 0.12 12.5 10.2 0.25 11.4 2.5 2.9 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family BMFP PF04380.8 EIE78443.1 - 0.12 12.5 3.6 8.2 6.6 0.1 3.4 3 1 1 4 4 4 0 Membrane fusogenic activity DUF883 PF05957.8 EIE78443.1 - 0.14 12.6 7.3 0.18 12.2 1.3 3.1 2 2 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF1342 PF07072.6 EIE78443.1 - 0.15 11.6 1.4 0.61 9.7 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1342) LXG PF04740.7 EIE78443.1 - 0.17 11.6 6.4 0.87 9.3 1.3 2.5 2 1 0 2 2 2 0 LXG domain of WXG superfamily DUF2884 PF11101.3 EIE78443.1 - 0.19 11.0 5.6 0.5 9.7 2.1 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF2884) LMBR1 PF04791.11 EIE78443.1 - 0.36 9.3 2.1 0.25 9.8 0.3 1.6 2 0 0 2 2 2 0 LMBR1-like membrane protein DUF1664 PF07889.7 EIE78443.1 - 0.53 10.0 5.2 0.14 11.9 1.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Laminin_II PF06009.7 EIE78443.1 - 0.63 9.7 6.7 1.4 8.6 0.0 2.7 2 1 1 3 3 3 0 Laminin Domain II HsbA PF12296.3 EIE78443.1 - 0.65 9.8 5.3 3.7 7.4 1.1 2.7 1 1 2 3 3 3 0 Hydrophobic surface binding protein A YtxH PF12732.2 EIE78443.1 - 1.2 9.5 11.3 0.13 12.6 1.2 3.2 1 1 1 2 2 2 0 YtxH-like protein TMPIT PF07851.8 EIE78443.1 - 1.5 7.8 6.6 0.18 10.8 1.5 1.6 2 0 0 2 2 2 0 TMPIT-like protein Phasin PF05597.6 EIE78443.1 - 1.5 8.5 9.8 5.8 6.6 0.5 3.0 2 1 1 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DivIVA PF05103.8 EIE78443.1 - 1.7 8.7 9.1 1.4 9.0 3.4 2.1 2 0 0 2 2 2 0 DivIVA protein Fzo_mitofusin PF04799.8 EIE78443.1 - 1.7 7.9 5.6 0.49 9.7 0.9 2.1 2 1 1 3 3 2 0 fzo-like conserved region DUF2681 PF10883.3 EIE78443.1 - 1.9 8.7 9.1 10 6.3 0.4 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2681) DUF972 PF06156.8 EIE78443.1 - 3.9 7.8 8.4 1.6 9.0 2.9 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF972) DUF148 PF02520.12 EIE78443.1 - 5.2 6.8 12.1 8.8 6.1 1.9 2.9 2 1 1 3 3 3 0 Domain of unknown function DUF148 Sdh_cyt PF01127.17 EIE78444.1 - 4e-25 88.0 1.0 4.8e-25 87.7 0.7 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit CsoS2_M PF12288.3 EIE78444.1 - 0.058 12.5 0.0 0.081 12.0 0.0 1.2 1 0 0 1 1 1 0 Carboxysome shell peptide mid-region Ribosomal_S14 PF00253.16 EIE78445.1 - 1.8e-19 68.8 3.7 2e-19 68.7 2.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF4428 PF14471.1 EIE78445.1 - 0.066 12.9 0.1 0.084 12.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) DUF1451 PF07295.6 EIE78445.1 - 0.068 12.9 0.2 0.068 12.9 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1451) SH3_9 PF14604.1 EIE78446.1 - 5.4e-11 41.8 0.0 2.5e-10 39.7 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 EIE78446.1 - 8.7e-11 41.0 0.0 1.7e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EIE78446.1 - 1.3e-07 31.0 0.0 2.3e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 EIE78446.1 - 0.004 17.3 0.0 0.007 16.5 0.0 1.4 1 0 0 1 1 1 1 Bacterial SH3 domain MFS_1 PF07690.11 EIE78447.1 - 2.5e-24 85.6 13.5 2.5e-24 85.6 9.3 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1700 PF08006.6 EIE78447.1 - 2.4 7.4 6.8 0.27 10.5 1.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1700) HMG_box PF00505.14 EIE78448.1 - 1.6e-15 57.0 0.4 2.6e-15 56.4 0.3 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EIE78448.1 - 1.8e-11 44.2 0.6 2.7e-11 43.6 0.4 1.3 1 0 0 1 1 1 1 HMG-box domain CHDNT PF08073.7 EIE78448.1 - 0.0034 17.0 0.0 0.0057 16.3 0.0 1.3 1 0 0 1 1 1 1 CHDNT (NUC034) domain HMG_box_5 PF14887.1 EIE78448.1 - 0.085 12.6 0.1 0.16 11.7 0.0 1.4 1 1 0 1 1 1 0 HMG (high mobility group) box 5 DSPc PF00782.15 EIE78449.1 - 8.5e-06 25.3 0.0 1.1e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EIE78449.1 - 2.8e-05 23.6 0.0 3.2e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase zf-C2H2 PF00096.21 EIE78450.1 - 5.4e-09 35.8 9.7 3.2e-05 23.9 1.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIE78450.1 - 1.8e-07 31.1 6.1 9.9e-07 28.7 1.8 2.7 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EIE78450.1 - 2.4e-07 30.5 8.7 0.0005 20.1 0.9 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 EIE78450.1 - 0.00074 19.6 2.9 0.67 10.2 0.3 3.4 3 0 0 3 3 3 2 Zinc-finger of C2H2 type Rsm1 PF08600.5 EIE78450.1 - 0.014 15.2 1.3 0.024 14.4 0.1 2.1 3 0 0 3 3 3 0 Rsm1-like Polysacc_deac_1 PF01522.16 EIE78451.1 - 2.6e-27 94.9 0.1 6.5e-27 93.6 0.1 1.7 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF3319 PF11782.3 EIE78451.1 - 0.16 11.7 3.3 3.5 7.5 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3319) DDE_3 PF13358.1 EIE78452.1 - 1.4e-23 83.3 0.0 8.6e-23 80.6 0.0 2.2 1 1 0 1 1 1 1 DDE superfamily endonuclease RasGAP PF00616.14 EIE78453.1 - 1.8e-37 128.9 0.2 9.3e-37 126.6 0.0 2.4 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.1 EIE78453.1 - 3.5e-19 69.1 0.5 1.4e-18 67.2 0.3 2.1 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain HEAT PF02985.17 EIE78453.1 - 0.031 14.3 3.1 6.4 7.1 0.0 4.2 3 0 0 3 3 3 0 HEAT repeat Peptidase_M13_N PF05649.8 EIE78454.1 - 1.6e-23 83.4 0.1 1.9e-23 83.1 0.1 1.0 1 0 0 1 1 1 1 Peptidase family M13 Phage_integrase PF00589.17 EIE78455.1 - 3.7e-07 29.9 0.0 4.7e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family Mis12 PF05859.7 EIE78457.1 - 0.31 10.8 0.1 0.31 10.8 0.0 2.5 2 0 0 2 2 2 0 Mis12 protein CAF1A PF12253.3 EIE78458.1 - 3.7e-18 65.3 0.3 8.6e-18 64.2 0.2 1.7 1 0 0 1 1 1 1 Chromatin assembly factor 1 subunit A Zip PF02535.17 EIE78459.1 - 3.6e-44 151.0 9.0 4e-44 150.9 6.3 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter HupE_UreJ PF04955.7 EIE78459.1 - 0.6 9.3 7.9 0.2 10.9 1.8 2.4 2 1 0 2 2 2 0 HupE / UreJ protein ChaC PF04752.7 EIE78460.1 - 1.9e-42 145.2 1.1 7.3e-20 71.6 0.0 3.0 1 1 2 3 3 3 3 ChaC-like protein VTC PF09359.5 EIE78461.1 - 3.8e-09 35.9 6.5 1.9e-07 30.3 4.5 2.3 1 1 0 1 1 1 1 VTC domain SPX PF03105.14 EIE78461.1 - 0.15 11.8 0.1 0.15 11.8 0.0 3.1 2 1 2 4 4 4 0 SPX domain Snf7 PF03357.16 EIE78462.1 - 4.7e-22 78.1 18.0 5.8e-22 77.8 12.5 1.2 1 0 0 1 1 1 1 Snf7 Ist1 PF03398.9 EIE78462.1 - 0.00026 20.4 1.6 0.00041 19.7 1.1 1.3 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway DUF1049 PF06305.6 EIE78462.1 - 0.4 10.1 1.6 0.86 9.1 1.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) LRR_6 PF13516.1 EIE78463.1 - 1.3e-17 61.8 6.9 0.00033 20.4 0.1 7.8 9 0 0 9 9 9 5 Leucine Rich repeat LRR_4 PF12799.2 EIE78463.1 - 7.1e-10 38.2 9.2 0.0047 16.5 0.3 6.3 3 2 4 7 7 7 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EIE78463.1 - 1.4e-09 36.5 0.1 2.2 8.6 0.0 7.6 8 1 0 8 8 8 1 Leucine Rich Repeat LRR_8 PF13855.1 EIE78463.1 - 9e-07 28.5 8.1 0.015 15.0 0.5 6.1 5 2 1 6 6 6 2 Leucine rich repeat LRR_7 PF13504.1 EIE78463.1 - 0.056 13.6 9.6 20 5.9 0.1 6.2 8 0 0 8 8 8 0 Leucine rich repeat Stn1 PF10451.4 EIE78463.1 - 0.66 8.7 2.8 0.95 8.2 2.0 1.3 1 0 0 1 1 1 0 Telomere regulation protein Stn1 SDA1 PF05285.7 EIE78463.1 - 0.79 8.9 18.8 1.1 8.4 13.0 1.2 1 0 0 1 1 1 0 SDA1 Merozoite_SPAM PF07133.6 EIE78463.1 - 3.2 7.6 25.4 7.9 6.3 16.7 2.0 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) Metallophos PF00149.23 EIE78464.1 - 6.9e-08 32.1 4.6 1.6e-07 30.8 3.2 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Ribosomal_L22e PF01776.12 EIE78465.1 - 4e-50 168.4 1.8 4.5e-50 168.3 1.2 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family Herpes_gE PF02480.11 EIE78466.1 - 0.0017 16.7 0.3 0.0023 16.2 0.2 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E DUF1191 PF06697.7 EIE78466.1 - 0.0034 16.2 0.1 0.0047 15.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) EphA2_TM PF14575.1 EIE78466.1 - 0.026 14.8 0.1 0.28 11.5 0.0 2.5 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.1 EIE78466.1 - 0.12 12.0 6.4 0.084 12.5 3.1 1.7 1 1 1 2 2 2 0 TMEM154 protein family LIM PF00412.17 EIE78468.1 - 3.9e-13 49.2 24.6 1.3e-11 44.4 5.2 3.1 3 0 0 3 3 3 2 LIM domain zinc_ribbon_2 PF13240.1 EIE78468.1 - 0.025 14.0 11.2 4.5 6.8 0.4 4.4 4 0 0 4 4 4 0 zinc-ribbon domain Ank_2 PF12796.2 EIE78469.1 - 3.3e-23 81.8 4.4 1.5e-15 57.2 0.6 2.3 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 EIE78469.1 - 1.8e-18 65.3 0.1 2e-08 33.6 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EIE78469.1 - 1.7e-16 60.2 0.7 1.5e-12 47.6 0.2 2.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIE78469.1 - 3.4e-16 57.7 0.2 1.1e-08 34.4 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 EIE78469.1 - 1.2e-14 53.9 0.3 2.6e-07 30.6 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) DUF2945 PF11160.3 EIE78469.1 - 0.016 14.9 0.0 0.038 13.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2945) LRR_6 PF13516.1 EIE78470.1 - 0.00068 19.4 3.9 7.2 7.0 0.0 5.2 4 1 0 4 4 4 1 Leucine Rich repeat F-box-like PF12937.2 EIE78470.1 - 0.024 14.3 0.0 0.056 13.1 0.0 1.7 1 0 0 1 1 1 0 F-box-like LRR_2 PF07723.8 EIE78470.1 - 0.038 14.4 0.8 0.16 12.5 0.1 2.5 3 0 0 3 3 3 0 Leucine Rich Repeat Pinin_SDK_memA PF04696.8 EIE78470.1 - 0.13 11.8 0.1 0.23 11.0 0.1 1.4 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region RhoGAP PF00620.22 EIE78471.1 - 1e-31 109.5 0.0 1.3e-31 109.2 0.0 1.1 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.18 EIE78472.1 - 1.6e-14 53.8 4.3 2e-14 53.5 0.0 2.4 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain IMD PF08397.6 EIE78472.1 - 0.0016 17.8 3.3 0.0024 17.2 2.3 1.4 1 0 0 1 1 1 1 IRSp53/MIM homology domain DUF1664 PF07889.7 EIE78472.1 - 0.12 12.2 2.5 0.13 12.0 0.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Adeno_E3_15_3 PF03307.9 EIE78472.1 - 0.12 12.1 0.4 0.31 10.7 0.1 1.9 2 0 0 2 2 2 0 Adenovirus 15.3kD protein in E3 region SPAM PF02090.10 EIE78472.1 - 0.14 12.1 3.4 0.15 12.0 1.2 1.7 2 0 0 2 2 2 0 Salmonella surface presentation of antigen gene type M protein DUF2664 PF10867.3 EIE78472.1 - 0.21 12.1 3.9 0.74 10.4 0.3 2.7 2 2 0 2 2 2 0 Protein of unknown function (DUF2664) Tom37_C PF11801.3 EIE78472.1 - 3.1 7.6 6.6 5.2 6.9 3.4 2.0 2 0 0 2 2 2 0 Tom37 C-terminal domain ATP-synt_E PF05680.7 EIE78474.1 - 5.6e-20 71.0 0.6 5.9e-20 71.0 0.4 1.1 1 0 0 1 1 1 1 ATP synthase E chain DUF3395 PF11875.3 EIE78474.1 - 0.044 13.4 0.1 0.051 13.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3395) dNK PF01712.14 EIE78474.1 - 0.068 13.0 0.2 0.081 12.8 0.1 1.1 1 0 0 1 1 1 0 Deoxynucleoside kinase Maf PF02545.9 EIE78475.1 - 1.4e-40 138.5 0.0 1.5e-40 138.3 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein SSURE PF11966.3 EIE78475.1 - 0.056 13.0 0.2 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 Fibronectin-binding repeat zf-H2C2_2 PF13465.1 EIE78476.1 - 0.0012 18.9 9.7 0.0058 16.8 0.7 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-Di19 PF05605.7 EIE78476.1 - 0.19 11.9 3.1 0.42 10.7 2.2 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Sec23_helical PF04815.10 EIE78477.1 - 3.3e-20 71.4 0.4 4.5e-20 71.0 0.3 1.2 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EIE78477.1 - 2.8e-12 46.9 0.0 5.1e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain DUF3329 PF11808.3 EIE78477.1 - 0.06 13.4 0.1 0.1 12.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3329) zf-Sec23_Sec24 PF04810.10 EIE78478.1 - 1.8e-16 59.4 4.0 4.5e-16 58.1 2.8 1.8 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger zf-C3HC4_3 PF13920.1 EIE78479.1 - 3e-06 26.7 6.5 3e-06 26.7 4.5 3.6 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIE78479.1 - 0.015 14.9 8.8 0.015 14.9 6.1 3.7 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Not1 PF04054.10 EIE78480.1 - 5.5e-35 120.9 2.7 5.5e-35 120.9 1.9 1.9 1 1 1 2 2 2 1 CCR4-Not complex component, Not1 USP7_ICP0_bdg PF12436.3 EIE78480.1 - 0.015 14.5 0.1 0.045 12.9 0.1 1.7 1 1 0 1 1 1 0 ICP0-binding domain of Ubiquitin-specific protease 7 ATP-synt_F PF01990.12 EIE78481.1 - 1.3e-31 108.7 0.4 1.6e-31 108.5 0.3 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DXP_synthase_N PF13292.1 EIE78481.1 - 0.04 12.8 0.1 0.07 12.0 0.1 1.3 1 1 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase Eapp_C PF10238.4 EIE78482.1 - 2.8e-23 82.3 12.3 8.2e-12 45.1 1.1 2.9 1 1 1 2 2 2 2 E2F-associated phosphoprotein Yippee-Mis18 PF03226.9 EIE78482.1 - 0.027 14.5 0.6 0.047 13.7 0.3 1.4 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF2296 PF10058.4 EIE78482.1 - 0.035 13.8 0.0 0.16 11.7 0.0 1.9 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) Cript PF10235.4 EIE78482.1 - 0.049 13.9 0.3 0.061 13.6 0.2 1.2 1 0 0 1 1 1 0 Microtubule-associated protein CRIPT Pkinase PF00069.20 EIE78483.1 - 1.6e-52 178.2 0.0 2.3e-52 177.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE78483.1 - 3.4e-34 118.0 0.0 4.7e-34 117.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE78483.1 - 5e-07 28.9 0.0 7.7e-07 28.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EIE78483.1 - 0.14 10.9 0.0 0.38 9.5 0.0 1.6 2 0 0 2 2 2 0 Seadornavirus VP7 Chitin_synth_2 PF03142.10 EIE78484.1 - 7.6e-264 875.9 0.1 1.1e-263 875.4 0.1 1.2 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 EIE78484.1 - 6.5e-13 48.8 2.1 2.5e-12 46.8 1.5 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EIE78484.1 - 1.1e-12 48.3 0.0 2.7e-10 40.4 0.0 2.7 2 1 0 2 2 2 2 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EIE78484.1 - 0.00017 21.3 0.0 0.014 15.0 0.0 2.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 Cyt-b5 PF00173.23 EIE78484.1 - 0.00032 20.4 0.0 0.0011 18.6 0.0 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glyco_transf_21 PF13506.1 EIE78484.1 - 0.0021 17.3 0.0 0.013 14.8 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 21 TraL PF07178.6 EIE78484.1 - 0.026 14.5 0.5 0.026 14.5 0.4 2.6 2 1 0 2 2 2 0 TraL protein Cullin PF00888.17 EIE78485.1 - 2.2e-22 79.3 1.8 3.7e-22 78.6 0.1 2.0 2 0 0 2 2 2 1 Cullin family DUF3153 PF11353.3 EIE78485.1 - 0.015 14.7 2.4 0.028 13.8 1.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3153) RPN7 PF10602.4 EIE78486.1 - 3.8e-58 195.7 4.2 5.6e-58 195.2 2.9 1.2 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 EIE78486.1 - 5.4e-14 52.3 1.7 1.1e-13 51.3 0.1 2.3 3 1 0 3 3 3 1 PCI domain SAC3_GANP PF03399.11 EIE78486.1 - 0.0006 19.4 2.0 0.00096 18.7 1.4 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family HTH_DeoR PF08220.7 EIE78486.1 - 0.0069 15.8 0.0 0.015 14.7 0.0 1.6 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain PCI_Csn8 PF10075.4 EIE78486.1 - 0.022 14.5 0.1 0.038 13.7 0.1 1.5 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 DUF1672 PF07901.6 EIE78486.1 - 0.045 12.7 0.9 0.085 11.8 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1672) SpoIIID PF12116.3 EIE78486.1 - 0.079 12.9 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Stage III sporulation protein D TPR_8 PF13181.1 EIE78486.1 - 0.42 10.5 3.5 1.8 8.5 2.4 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.1 EIE78486.1 - 2.7 8.6 6.0 1.4 9.5 1.8 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat PCI PF01399.22 EIE78487.1 - 3e-19 69.2 0.1 3e-19 69.2 0.1 2.9 3 1 0 3 3 3 1 PCI domain TPR_11 PF13414.1 EIE78487.1 - 0.0058 16.2 6.8 0.37 10.4 0.1 3.8 4 0 0 4 4 4 2 TPR repeat TPR_16 PF13432.1 EIE78487.1 - 0.054 14.1 5.5 2.2 9.0 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 EIE78487.1 - 0.074 12.8 8.6 3 7.8 0.1 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat Apc5 PF12862.2 EIE78487.1 - 0.18 11.6 1.8 2.2 8.1 0.1 3.1 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 5 TPR_12 PF13424.1 EIE78487.1 - 1.5 8.7 13.7 4 7.4 0.7 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 EIE78487.1 - 4.5 7.9 6.8 40 4.9 0.0 4.5 6 0 0 6 6 6 0 Tetratricopeptide repeat DnaJ PF00226.26 EIE78488.1 - 5.2e-27 93.3 1.7 8.4e-27 92.7 1.2 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EIE78488.1 - 1.7e-22 79.1 0.6 2.1e-18 65.9 0.0 2.5 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EIE78488.1 - 1.4e-14 53.8 20.0 2.2e-14 53.2 13.9 1.3 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EIE78488.1 - 0.028 14.1 12.3 0.27 10.9 2.0 2.2 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family KH_1 PF00013.24 EIE78489.1 - 2.8e-25 87.7 0.7 2.1e-09 36.8 0.0 5.8 6 0 0 6 6 6 4 KH domain KH_3 PF13014.1 EIE78489.1 - 1.6e-19 69.0 4.5 1.7e-06 27.5 0.1 6.3 7 0 0 7 7 7 3 KH domain HATPase_c_5 PF14501.1 EIE78489.1 - 0.045 13.4 0.1 0.15 11.7 0.0 1.9 1 0 0 1 1 1 0 GHKL domain Endotoxin_M PF00555.14 EIE78490.1 - 0.029 14.1 1.8 0.036 13.8 1.2 1.2 1 1 0 1 1 1 0 delta endotoxin zf-C3HC4_3 PF13920.1 EIE78491.1 - 8.9e-07 28.4 7.1 8.9e-07 28.4 4.9 4.1 4 0 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIE78491.1 - 6e-06 26.1 34.0 2.5e-05 24.1 6.3 4.6 4 1 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) IBR PF01485.16 EIE78491.1 - 1.1e-05 25.2 3.2 1.1e-05 25.2 2.2 4.9 2 1 1 3 3 3 1 IBR domain zf-RING_2 PF13639.1 EIE78491.1 - 4.9e-05 23.0 8.4 4.9e-05 23.0 5.8 4.0 4 0 0 4 4 4 2 Ring finger domain zf-C3HC4 PF00097.20 EIE78491.1 - 0.00046 19.7 7.1 0.00046 19.7 4.9 4.2 3 2 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIE78491.1 - 0.00086 18.9 8.5 0.00086 18.9 5.9 4.4 4 0 0 4 4 4 2 zinc-RING finger domain DOG1 PF14144.1 EIE78491.1 - 0.14 12.2 0.0 2.4 8.2 0.0 2.5 2 0 0 2 2 2 0 Seed dormancy control zf-C3HC4_4 PF15227.1 EIE78491.1 - 4.9 7.1 34.3 0.17 11.8 0.6 5.0 4 2 1 5 5 5 0 zinc finger of C3HC4-type, RING Response_reg PF00072.19 EIE78492.1 - 2.2e-12 46.9 0.5 0.00043 20.2 0.0 3.5 2 1 0 2 2 2 2 Response regulator receiver domain DUF2852 PF11014.3 EIE78492.1 - 0.046 13.6 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) SCO1-SenC PF02630.9 EIE78493.1 - 1.3e-17 63.9 0.1 1.5e-17 63.7 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 EIE78493.1 - 0.00081 19.0 0.0 0.0014 18.3 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family DUF3886 PF13025.1 EIE78493.1 - 0.23 11.4 3.2 0.39 10.7 2.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) zf-C2H2_jaz PF12171.3 EIE78494.1 - 3.5e-09 36.5 7.7 4.8e-09 36.0 5.4 1.2 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EIE78494.1 - 0.00071 19.6 0.6 0.00081 19.4 0.4 1.1 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 EIE78494.1 - 0.001 19.1 5.1 0.0015 18.6 3.5 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-LYAR PF08790.6 EIE78494.1 - 0.16 11.6 1.4 0.26 11.0 0.9 1.3 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger zf-C2H2 PF00096.21 EIE78494.1 - 1.9 9.0 4.6 2.8 8.4 3.2 1.3 1 0 0 1 1 1 0 Zinc finger, C2H2 type DEAD PF00270.24 EIE78495.1 - 1.2e-36 125.7 0.9 1.5e-36 125.4 0.6 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EIE78495.1 - 3.3e-06 27.0 0.0 4.8e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 EIE78495.1 - 0.0012 18.5 0.0 0.0027 17.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EIE78495.1 - 0.0042 16.8 0.1 0.026 14.2 0.1 2.1 2 0 0 2 2 2 1 Part of AAA domain CMS1 PF14617.1 EIE78495.1 - 0.011 14.7 0.0 0.021 13.9 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Helicase_RecD PF05127.9 EIE78495.1 - 0.02 14.5 0.0 0.028 14.0 0.0 1.3 1 1 0 1 1 1 0 Helicase DUF2075 PF09848.4 EIE78495.1 - 0.047 12.6 0.0 0.067 12.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) FBA_3 PF08268.7 EIE78495.1 - 0.08 12.6 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 F-box associated domain Homeobox PF00046.24 EIE78496.1 - 5.5e-18 64.3 4.3 1e-17 63.4 3.0 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EIE78496.1 - 0.038 13.7 0.4 0.11 12.2 0.1 1.8 2 0 0 2 2 2 0 Homeobox KN domain Pkinase PF00069.20 EIE78497.1 - 2.6e-70 236.5 0.0 4.5e-70 235.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE78497.1 - 2.1e-56 190.8 0.0 3.5e-56 190.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE78497.1 - 4.6e-07 29.1 0.0 0.00013 21.0 0.0 2.4 1 1 1 2 2 2 2 Kinase-like C1_1 PF00130.17 EIE78497.1 - 0.00014 21.5 12.0 0.00032 20.3 8.3 1.7 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) RIO1 PF01163.17 EIE78497.1 - 0.022 14.1 0.0 0.05 12.9 0.0 1.6 1 0 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.6 EIE78497.1 - 0.035 12.9 1.0 0.074 11.8 0.0 1.9 2 0 0 2 2 2 0 Seadornavirus VP7 SAP PF02037.22 EIE78498.1 - 2.1e-11 43.0 0.6 4.2e-11 42.0 0.4 1.6 1 0 0 1 1 1 1 SAP domain Zn_clus PF00172.13 EIE78499.1 - 2.4e-08 33.7 16.0 4.2e-08 32.9 11.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BAF1_ABF1 PF04684.8 EIE78499.1 - 8.7e-06 24.8 15.0 9.7e-06 24.6 10.4 1.2 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor Zip PF02535.17 EIE78499.1 - 0.6 9.0 5.4 0.75 8.7 3.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Cellulose_synt PF03552.9 EIE78499.1 - 6.5 4.9 6.6 8.1 4.5 4.6 1.1 1 0 0 1 1 1 0 Cellulose synthase DUF4175 PF13779.1 EIE78499.1 - 9 3.8 20.3 12 3.4 14.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) TPMT PF05724.6 EIE78500.1 - 3.1e-29 101.9 0.0 4.9e-29 101.3 0.0 1.3 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_25 PF13649.1 EIE78500.1 - 5.1e-06 26.7 0.0 6.9e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIE78500.1 - 8.6e-06 26.1 0.0 1.2e-05 25.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIE78500.1 - 9.2e-05 22.9 0.0 0.00015 22.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIE78500.1 - 0.0001 21.9 0.0 0.00013 21.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIE78500.1 - 0.0065 16.4 0.0 0.015 15.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIE78500.1 - 0.013 15.9 0.0 0.017 15.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Rhomboid PF01694.17 EIE78501.1 - 8.7e-18 64.7 2.9 8.7e-18 64.7 2.0 1.6 2 0 0 2 2 2 1 Rhomboid family Smac_DIABLO PF09057.5 EIE78502.1 - 0.049 12.7 0.5 0.15 11.1 0.1 1.9 2 0 0 2 2 2 0 Second Mitochondria-derived Activator of Caspases Trp_repressor PF01371.14 EIE78503.1 - 0.016 15.1 0.9 0.043 13.7 0.7 1.8 1 1 0 1 1 1 0 Trp repressor protein MCPVI PF02993.9 EIE78503.1 - 2.4 8.2 10.7 2.9 7.9 7.4 1.1 1 0 0 1 1 1 0 Minor capsid protein VI EHN PF06441.7 EIE78503.1 - 2.9 7.8 5.4 3.7 7.4 3.7 1.2 1 0 0 1 1 1 0 Epoxide hydrolase N terminus Gastrin PF00918.12 EIE78503.1 - 6.3 7.6 9.1 7.9 7.3 6.3 1.2 1 0 0 1 1 1 0 Gastrin/cholecystokinin family DUF4252 PF14060.1 EIE78503.1 - 7.8 6.0 14.5 11 5.5 10.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4252) Iron_permease PF04120.7 EIE78503.1 - 8.1 6.0 9.6 9.8 5.7 6.6 1.1 1 0 0 1 1 1 0 Low affinity iron permease RNA_pol_Rpb1_2 PF00623.15 EIE78503.1 - 8.9 6.2 8.0 11 5.9 5.5 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 2 PLDc_2 PF13091.1 EIE78506.1 - 7.5e-28 96.8 0.5 1.3e-27 96.0 0.1 1.6 2 0 0 2 2 2 1 PLD-like domain DUF1669 PF07894.7 EIE78506.1 - 4.4e-06 26.1 0.4 0.063 12.4 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1669) PLDc PF00614.17 EIE78506.1 - 0.0086 15.8 0.1 0.015 15.0 0.1 1.4 1 0 0 1 1 1 1 Phospholipase D Active site motif Pox_Ag35 PF03286.9 EIE78506.1 - 0.31 10.5 8.6 0.62 9.5 5.9 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF3373 PF11853.3 EIE78508.1 - 0.12 10.9 5.8 0.15 10.5 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) OmpH PF03938.9 EIE78508.1 - 0.63 9.9 27.1 1.2 9.0 18.8 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Aconitase PF00330.15 EIE78508.1 - 1 7.7 4.9 1.7 6.9 3.4 1.3 1 0 0 1 1 1 0 Aconitase family (aconitate hydratase) FLO_LFY PF01698.11 EIE78508.1 - 1.3 7.7 11.9 2.4 6.9 8.3 1.4 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF853 PF05872.7 EIE78508.1 - 1.4 7.1 11.1 2 6.6 7.7 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Cellulose_synt PF03552.9 EIE78508.1 - 1.5 6.9 6.6 2.2 6.4 4.6 1.1 1 0 0 1 1 1 0 Cellulose synthase NARP1 PF12569.3 EIE78508.1 - 2.2 6.9 15.2 3.4 6.3 10.6 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF4220 PF13968.1 EIE78508.1 - 2.5 7.0 5.9 3.9 6.4 4.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) CDC27 PF09507.5 EIE78508.1 - 4.1 6.5 33.6 5.4 6.1 23.3 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 FYDLN_acid PF09538.5 EIE78508.1 - 5.1 7.7 13.4 5.1 7.7 4.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) DUF4407 PF14362.1 EIE78508.1 - 7.5 5.4 16.8 1.4 7.7 9.5 1.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Ribosom_S12_S23 PF00164.20 EIE78509.1 - 3.2e-41 139.5 0.7 3.7e-41 139.3 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 zf-C2HC5 PF06221.8 EIE78510.1 - 4.3e-23 80.8 5.7 7e-23 80.1 4.0 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type DUF1977 PF09320.6 EIE78510.1 - 7.8 6.7 10.1 0.4 10.9 1.8 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF1977) Imm36 PF15597.1 EIE78511.1 - 0.032 14.3 0.0 0.036 14.2 0.0 1.2 1 0 0 1 1 1 0 Immunity protein 36 CTP_synth_N PF06418.9 EIE78512.1 - 4.5e-122 406.4 0.0 5.9e-122 406.0 0.0 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 EIE78512.1 - 6.1e-60 201.9 0.0 9.7e-60 201.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EIE78512.1 - 6.3e-07 29.0 0.0 1.6e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 Peptidase C26 CbiA PF01656.18 EIE78512.1 - 0.00026 20.4 0.0 0.00044 19.7 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Ribosomal_L13 PF00572.13 EIE78513.1 - 5.3e-25 87.9 0.0 9.2e-25 87.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L13 Enkurin PF13864.1 EIE78515.1 - 1.3e-06 28.5 2.3 1.3e-06 28.5 1.6 4.6 2 1 2 4 4 4 1 Calmodulin-binding Ribosomal_60s PF00428.14 EIE78515.1 - 0.00078 19.7 5.3 0.003 17.9 3.7 2.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein TPR_MLP1_2 PF07926.7 EIE78515.1 - 0.00095 18.9 0.0 0.00095 18.9 0.0 3.8 3 1 0 4 4 4 1 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.4 EIE78515.1 - 0.0028 17.4 13.1 0.0028 17.4 9.1 3.9 2 2 1 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Syntaxin PF00804.20 EIE78515.1 - 0.0038 17.3 2.9 0.0038 17.3 2.0 4.3 2 1 0 2 2 2 1 Syntaxin IncA PF04156.9 EIE78515.1 - 1.2 8.7 35.3 1.9 8.0 0.7 3.5 2 1 1 3 3 3 0 IncA protein TBPIP PF07106.8 EIE78515.1 - 1.3 8.5 35.6 3.7 7.0 2.2 3.3 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) UPF0184 PF03670.8 EIE78515.1 - 3.3 7.9 13.2 16 5.7 0.0 4.4 2 1 2 4 4 4 0 Uncharacterised protein family (UPF0184) Filament PF00038.16 EIE78515.1 - 6.3 6.1 34.6 0.078 12.4 7.3 3.3 2 2 1 3 3 3 0 Intermediate filament protein FAD_binding_6 PF00970.19 EIE78516.1 - 2.1e-31 107.9 0.0 3.2e-31 107.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EIE78516.1 - 2.7e-30 105.1 0.0 4.8e-30 104.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EIE78516.1 - 4.4e-06 26.6 0.0 0.00011 22.1 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EIE78516.1 - 0.019 14.9 0.0 0.033 14.1 0.0 1.4 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain Rap_GAP PF02145.10 EIE78517.1 - 4.5e-55 185.9 0.0 1.9e-54 183.8 0.0 2.0 2 0 0 2 2 2 1 Rap/ran-GAP DUF3384 PF11864.3 EIE78517.1 - 3.4e-50 170.8 1.3 3.4e-50 170.8 0.9 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3384) Tuberin PF03542.11 EIE78517.1 - 3.6e-37 128.2 5.1 2.1e-36 125.7 1.3 2.9 3 0 0 3 3 3 1 Tuberin Romo1 PF10247.4 EIE78518.1 - 5.1e-10 39.3 4.7 9.7e-10 38.5 3.2 1.5 1 1 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 SMK-1 PF04802.10 EIE78519.1 - 2.2e-23 82.8 2.6 3.8e-23 82.0 1.8 1.4 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 Fe_dep_repr_C PF02742.10 EIE78519.1 - 0.058 13.0 0.7 0.24 11.1 0.2 2.1 1 1 1 2 2 2 0 Iron dependent repressor, metal binding and dimerisation domain Astro_capsid PF03115.9 EIE78520.1 - 0.92 7.6 10.5 1.1 7.4 7.3 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor CRAL_TRIO PF00650.15 EIE78521.1 - 7.3e-40 136.0 0.0 1.6e-39 134.9 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EIE78521.1 - 9.4e-13 48.0 0.2 2.2e-12 46.9 0.1 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EIE78521.1 - 3.2e-09 36.8 0.0 6.1e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Sigma70_r4 PF04545.11 EIE78522.1 - 0.016 14.5 0.0 0.026 13.8 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 Sigma70_r3 PF04539.11 EIE78522.1 - 0.057 13.3 0.0 0.17 11.7 0.0 1.8 2 0 0 2 2 2 0 Sigma-70 region 3 AF2331-like PF14556.1 EIE78522.1 - 0.099 12.9 0.4 0.13 12.6 0.2 1.2 1 0 0 1 1 1 0 AF2331-like VEFS-Box PF09733.4 EIE78522.1 - 0.25 10.9 2.7 0.3 10.7 0.5 1.8 2 0 0 2 2 2 0 VEFS-Box of polycomb protein OPT PF03169.10 EIE78523.1 - 1e-93 314.8 38.0 1.2e-93 314.7 26.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Cpn60_TCP1 PF00118.19 EIE78524.1 - 9.7e-160 532.3 3.8 1.2e-159 532.0 2.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Pept_tRNA_hydro PF01195.14 EIE78525.1 - 1e-24 87.0 0.7 3.4e-15 56.0 0.3 2.3 1 1 1 2 2 2 2 Peptidyl-tRNA hydrolase DUF3876 PF12992.2 EIE78525.1 - 0.055 13.4 0.1 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3876) Saccharop_dh PF03435.13 EIE78526.1 - 5.5e-19 68.4 0.0 3.8e-18 65.6 0.0 1.9 2 0 0 2 2 2 1 Saccharopine dehydrogenase DUF3429 PF11911.3 EIE78526.1 - 0.011 15.7 0.2 0.02 14.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3429) Polysacc_synt_2 PF02719.10 EIE78526.1 - 0.029 13.2 0.0 0.052 12.4 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NmrA PF05368.8 EIE78526.1 - 0.12 11.5 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family HSF_DNA-bind PF00447.12 EIE78527.1 - 5.8e-37 126.0 3.7 5.8e-37 126.0 2.5 1.9 2 0 0 2 2 2 1 HSF-type DNA-binding Sigma70_ner PF04546.8 EIE78527.1 - 0.0027 17.3 2.5 0.0039 16.8 1.7 1.2 1 0 0 1 1 1 1 Sigma-70, non-essential region Aft1_OSA PF11785.3 EIE78527.1 - 0.0084 16.6 0.5 0.0084 16.6 0.4 2.0 2 0 0 2 2 2 1 Aft1 osmotic stress response (OSM) domain Phage_GP20 PF06810.6 EIE78527.1 - 0.05 13.0 6.4 0.092 12.1 4.4 1.4 1 0 0 1 1 1 0 Phage minor structural protein GP20 Phage_GPO PF05929.6 EIE78527.1 - 0.078 12.2 1.5 0.11 11.6 1.1 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase APG6 PF04111.7 EIE78527.1 - 0.084 11.9 5.5 0.12 11.3 3.8 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Cdc6_C PF09079.6 EIE78527.1 - 0.092 12.4 0.2 3.9 7.2 0.0 2.3 2 0 0 2 2 2 0 CDC6, C terminal DUF4093 PF13331.1 EIE78527.1 - 0.29 11.3 3.7 1.3 9.2 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4093) SseC PF04888.7 EIE78527.1 - 4.8 6.4 6.8 6.5 5.9 4.7 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family YukC PF10140.4 EIE78528.1 - 0.012 14.1 0.1 0.013 14.1 0.1 1.0 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC RST PF12174.3 EIE78528.1 - 0.074 12.8 0.4 0.17 11.7 0.1 1.6 1 1 1 2 2 2 0 RCD1-SRO-TAF4 (RST) plant domain Ceramidase PF05875.7 EIE78529.1 - 2.2e-32 112.2 11.9 6e-17 61.6 2.1 2.0 1 1 1 2 2 2 2 Ceramidase bZIP_1 PF00170.16 EIE78530.1 - 1.7e-10 40.7 14.4 6.5e-10 38.8 9.3 2.1 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EIE78530.1 - 6.9e-10 38.6 7.8 6.9e-10 38.6 5.4 1.9 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 EIE78530.1 - 0.00024 21.3 5.0 0.00043 20.5 3.4 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor Tropomyosin PF00261.15 EIE78530.1 - 0.0061 15.6 8.2 0.0089 15.1 5.7 1.2 1 0 0 1 1 1 1 Tropomyosin KIAA1430 PF13879.1 EIE78530.1 - 0.017 15.5 1.1 0.034 14.5 0.7 1.5 1 0 0 1 1 1 0 KIAA1430 homologue IncA PF04156.9 EIE78530.1 - 0.052 13.1 0.4 0.068 12.7 0.3 1.3 1 0 0 1 1 1 0 IncA protein DUF3552 PF12072.3 EIE78530.1 - 0.056 12.6 7.8 0.082 12.1 5.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF904 PF06005.7 EIE78530.1 - 0.083 13.1 5.0 0.1 12.9 2.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF904) Tup_N PF08581.5 EIE78530.1 - 0.21 11.7 3.8 5 7.3 2.6 2.2 1 1 0 1 1 1 0 Tup N-terminal DEAD PF00270.24 EIE78531.1 - 3.9e-20 72.0 0.0 7.2e-20 71.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIE78531.1 - 4.7e-11 42.4 0.0 1.1e-10 41.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIE78531.1 - 0.0021 17.9 0.4 0.0064 16.3 0.0 1.9 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2267 PF10025.4 EIE78532.1 - 0.14 12.2 0.0 0.45 10.5 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) RNA_pol_L_2 PF13656.1 EIE78533.1 - 2e-26 91.1 0.0 3e-26 90.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EIE78533.1 - 1.7e-10 39.8 0.0 3.3e-10 38.9 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb3/Rpb11 dimerisation domain GATA PF00320.22 EIE78534.1 - 1.9e-12 46.2 7.9 5.1e-12 44.9 5.5 1.7 1 0 0 1 1 1 1 GATA zinc finger Frataxin_Cyay PF01491.11 EIE78535.1 - 0.0058 16.4 0.1 0.008 15.9 0.0 1.2 1 0 0 1 1 1 1 Frataxin-like domain Borealin PF10512.4 EIE78535.1 - 0.13 12.1 1.1 0.73 9.7 0.1 2.2 1 1 2 3 3 3 0 Cell division cycle-associated protein 8 SF3b1 PF08920.5 EIE78535.1 - 0.14 12.2 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 Splicing factor 3B subunit 1 Glyco_transf_20 PF00982.16 EIE78536.1 - 3.5e-146 487.4 0.1 1.8e-136 455.4 0.0 2.2 1 1 1 2 2 2 2 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EIE78536.1 - 6.2e-50 169.3 0.0 1.8e-49 167.7 0.0 1.8 1 1 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.7 EIE78536.1 - 0.00015 21.4 0.1 0.00015 21.4 0.0 2.7 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Ldh_1_N PF00056.18 EIE78537.1 - 5.5e-47 159.1 0.2 7.8e-47 158.6 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 EIE78537.1 - 6.3e-47 159.5 0.0 9.3e-47 158.9 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 EIE78537.1 - 2.8e-05 22.9 0.0 6.1e-05 21.8 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.15 EIE78537.1 - 0.0012 18.7 0.1 0.0025 17.7 0.1 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Glyco_hydro_4 PF02056.11 EIE78537.1 - 0.016 14.5 1.7 1.1 8.5 0.2 3.0 2 1 1 3 3 3 0 Family 4 glycosyl hydrolase Semialdhyde_dh PF01118.19 EIE78537.1 - 0.025 14.9 0.5 0.13 12.5 0.0 2.1 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 EIE78537.1 - 0.034 13.5 0.0 0.068 12.5 0.0 1.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 EIE78537.1 - 0.046 12.8 1.6 0.26 10.3 0.2 2.6 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain CAF1 PF04857.15 EIE78538.1 - 2.8e-30 105.5 0.0 3.4e-30 105.2 0.0 1.0 1 0 0 1 1 1 1 CAF1 family ribonuclease DUF3391 PF11871.3 EIE78539.1 - 0.0021 18.2 1.3 0.0031 17.7 0.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3391) Strep_SA_rep PF06696.6 EIE78539.1 - 0.027 14.2 1.4 0.027 14.2 1.0 2.1 2 0 0 2 2 2 0 Streptococcal surface antigen repeat bZIP_1 PF00170.16 EIE78539.1 - 0.049 13.5 4.4 0.079 12.9 3.1 1.3 1 0 0 1 1 1 0 bZIP transcription factor Mnd1 PF03962.10 EIE78539.1 - 0.057 13.0 4.7 0.078 12.6 2.9 1.4 1 1 1 2 2 2 0 Mnd1 family DUF2077 PF09850.4 EIE78539.1 - 0.059 12.7 0.0 0.081 12.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2077) EMP24_GP25L PF01105.19 EIE78539.1 - 0.063 12.9 2.9 0.083 12.6 2.0 1.3 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD ThiI PF02568.9 EIE78539.1 - 0.22 10.9 1.9 0.31 10.4 1.3 1.2 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) Dzip-like_N PF13815.1 EIE78539.1 - 9.8 6.0 8.0 30 4.4 3.0 2.4 2 1 0 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal AMP-binding PF00501.23 EIE78540.1 - 1.1e-92 310.6 0.0 1.3e-92 310.4 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EIE78540.1 - 1.1e-08 35.8 0.0 3e-08 34.4 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain zf-C2H2 PF00096.21 EIE78542.1 - 2.5e-09 36.9 19.0 0.0022 18.2 1.0 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIE78542.1 - 0.00042 20.4 6.5 0.00042 20.4 4.5 3.0 3 0 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.2 EIE78542.1 - 0.0024 17.9 5.0 0.07 13.3 1.3 2.9 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 EIE78542.1 - 0.007 16.6 18.0 0.015 15.5 1.8 3.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EIE78542.1 - 0.1 12.7 7.5 0.084 13.0 1.2 3.0 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.13 EIE78542.1 - 2.5 8.5 8.3 0.45 10.9 2.6 2.0 2 0 0 2 2 2 0 TRAF-type zinc finger zf-C2H2_2 PF12756.2 EIE78542.1 - 3.1 7.9 9.7 52 4.0 4.9 3.5 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) MitMem_reg PF13012.1 EIE78543.1 - 7.5e-23 80.8 0.6 1.2e-22 80.1 0.4 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.16 EIE78543.1 - 1.9e-13 50.1 0.0 4.6e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease UPF0172 PF03665.8 EIE78543.1 - 0.0071 15.8 0.0 0.02 14.4 0.0 1.7 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0172) Pkip-1 PF06878.6 EIE78543.1 - 0.091 12.6 0.1 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 Pkip-1 protein AAA PF00004.24 EIE78544.1 - 2.2e-41 141.1 0.1 5.1e-41 139.9 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EIE78544.1 - 9.3e-06 25.4 0.1 5.3e-05 22.9 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EIE78544.1 - 1.6e-05 24.9 0.1 0.0022 17.9 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 EIE78544.1 - 9.7e-05 21.5 0.0 0.00025 20.1 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EIE78544.1 - 0.00015 21.9 0.3 0.014 15.5 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.9 EIE78544.1 - 0.00023 21.1 0.0 0.0011 18.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 EIE78544.1 - 0.00077 18.4 0.0 0.0014 17.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) PhoH PF02562.11 EIE78544.1 - 0.00077 18.7 0.1 0.0089 15.2 0.0 2.1 2 0 0 2 2 2 1 PhoH-like protein AAA_17 PF13207.1 EIE78544.1 - 0.0012 19.6 0.3 0.0034 18.1 0.0 2.0 2 1 0 2 2 1 1 AAA domain Mg_chelatase PF01078.16 EIE78544.1 - 0.0033 16.6 0.2 0.011 14.8 0.0 1.9 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 EIE78544.1 - 0.004 17.0 0.1 0.0098 15.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EIE78544.1 - 0.0045 16.7 0.1 0.01 15.5 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 EIE78544.1 - 0.005 16.7 0.0 0.0089 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EIE78544.1 - 0.0051 16.2 0.1 0.0099 15.3 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 EIE78544.1 - 0.014 14.5 0.1 0.041 12.9 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_25 PF13481.1 EIE78544.1 - 0.021 14.2 0.8 0.33 10.3 0.1 2.4 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.1 EIE78544.1 - 0.033 13.7 0.1 0.085 12.4 0.1 1.6 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EIE78544.1 - 0.05 12.7 0.0 0.13 11.3 0.0 1.7 1 0 0 1 1 1 0 KaiC NACHT PF05729.7 EIE78544.1 - 0.063 12.9 0.2 1.6 8.3 0.0 2.3 1 1 1 2 2 2 0 NACHT domain Sigma54_activat PF00158.21 EIE78544.1 - 0.077 12.4 0.0 0.25 10.8 0.0 1.8 2 0 0 2 2 1 0 Sigma-54 interaction domain RNA_helicase PF00910.17 EIE78544.1 - 0.1 12.8 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase DUF2422 PF10337.4 EIE78545.1 - 4.3e-14 52.1 0.1 4.3e-14 52.1 0.1 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2422) FUSC_2 PF13515.1 EIE78545.1 - 1.3e-13 50.9 8.4 1.3e-13 50.9 5.9 2.5 2 0 0 2 2 2 1 Fusaric acid resistance protein-like FUSC PF04632.7 EIE78545.1 - 4.1e-11 42.0 8.1 2.3e-08 32.9 4.2 2.5 2 0 0 2 2 2 2 Fusaric acid resistance protein family DUF2421 PF10334.4 EIE78545.1 - 1.7e-09 37.6 0.2 5.2e-09 36.0 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) ALMT PF11744.3 EIE78545.1 - 9.2e-07 27.8 4.4 9.2e-07 27.8 3.0 3.1 3 0 0 3 3 3 2 Aluminium activated malate transporter ABC_cobalt PF09819.4 EIE78545.1 - 0.018 14.9 12.2 0.031 14.2 1.7 2.8 3 0 0 3 3 3 0 ABC-type cobalt transport system, permease component DUF2205 PF10224.4 EIE78546.1 - 9.5e-16 57.1 1.7 1.1e-15 56.9 1.2 1.2 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) Kinesin-related PF06548.6 EIE78546.1 - 0.00062 18.4 0.3 0.00065 18.3 0.2 1.0 1 0 0 1 1 1 1 Kinesin-related Kinesin-relat_1 PF12711.2 EIE78546.1 - 0.0031 17.8 3.6 0.0054 17.0 0.6 2.0 1 1 1 2 2 2 1 Kinesin motor DUF972 PF06156.8 EIE78546.1 - 0.0061 16.8 0.5 0.0068 16.7 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF972) HOOK PF05622.7 EIE78546.1 - 0.0085 13.9 0.2 0.0093 13.8 0.2 1.0 1 0 0 1 1 1 1 HOOK protein DUF3135 PF11333.3 EIE78546.1 - 0.042 13.9 0.4 0.055 13.6 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3135) CASP_C PF08172.7 EIE78546.1 - 0.044 12.7 0.2 0.041 12.8 0.1 1.1 1 0 0 1 1 1 0 CASP C terminal DUF4172 PF13776.1 EIE78546.1 - 0.052 13.6 0.8 0.1 12.6 0.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4172) Reo_sigmaC PF04582.7 EIE78546.1 - 0.063 12.4 0.3 0.066 12.3 0.2 1.0 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF1635 PF07795.6 EIE78546.1 - 0.065 12.5 0.2 0.076 12.3 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Trns_repr_metal PF02583.12 EIE78546.1 - 0.075 13.2 0.5 0.13 12.5 0.3 1.6 1 1 0 1 1 1 0 Metal-sensitive transcriptional repressor TBPIP PF07106.8 EIE78546.1 - 0.14 11.7 1.4 0.18 11.3 1.0 1.1 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Cep57_CLD_2 PF14197.1 EIE78546.1 - 0.15 12.0 2.2 0.24 11.3 1.1 1.5 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 Tektin PF03148.9 EIE78546.1 - 0.18 10.3 2.3 0.2 10.1 1.6 1.1 1 0 0 1 1 1 0 Tektin family Striatin PF08232.7 EIE78546.1 - 0.22 11.8 2.3 0.29 11.4 1.6 1.3 1 1 0 1 1 1 0 Striatin family FAR1 PF03101.10 EIE78547.1 - 7.3e-08 32.8 1.0 2.1e-07 31.3 0.7 1.8 1 0 0 1 1 1 1 FAR1 DNA-binding domain Cyclin_N PF00134.18 EIE78549.1 - 1e-10 41.2 0.2 1.9e-10 40.4 0.2 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.14 EIE78549.1 - 0.0008 19.1 0.0 0.0017 18.1 0.0 1.5 1 0 0 1 1 1 1 Transcription factor TFIIB repeat Cyclin_C PF02984.14 EIE78549.1 - 0.0062 16.4 0.0 0.066 13.1 0.0 2.2 2 0 0 2 2 2 1 Cyclin, C-terminal domain ING PF12998.2 EIE78550.1 - 1.3e-08 35.0 0.8 2.3e-08 34.2 0.6 1.4 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding EzrA PF06160.7 EIE78550.1 - 0.034 12.3 0.9 0.037 12.2 0.7 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Vps53_N PF04100.7 EIE78550.1 - 0.076 11.7 0.2 0.085 11.6 0.1 1.0 1 0 0 1 1 1 0 Vps53-like, N-terminal DUF2962 PF11176.3 EIE78550.1 - 0.51 9.8 4.2 1.1 8.8 2.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2962) Suc_Fer-like PF06999.7 EIE78551.1 - 1.1e-47 162.9 0.0 1.4e-47 162.6 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like DUF2420 PF10336.4 EIE78551.1 - 0.065 12.8 0.1 0.32 10.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2420) Sel1 PF08238.7 EIE78552.1 - 1.8e-18 66.5 20.6 9.1e-05 22.9 0.0 6.1 6 0 0 6 6 6 4 Sel1 repeat TPR_8 PF13181.1 EIE78552.1 - 3.4e-07 29.5 2.4 0.00027 20.4 0.4 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 EIE78552.1 - 8.4e-05 22.1 5.4 0.00027 20.5 0.7 3.0 3 0 0 3 3 3 1 TPR repeat TPR_19 PF14559.1 EIE78552.1 - 0.00026 21.2 2.4 0.0028 17.9 0.6 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 EIE78552.1 - 0.00041 20.0 7.3 0.0038 17.0 0.4 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 EIE78552.1 - 0.0021 18.1 2.9 0.025 14.6 0.3 2.7 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EIE78552.1 - 0.0023 17.5 3.5 0.0074 16.0 0.6 3.2 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EIE78552.1 - 0.0026 17.6 8.9 0.019 14.8 1.7 3.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EIE78552.1 - 0.0051 17.3 3.3 0.046 14.3 0.1 3.6 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EIE78552.1 - 0.013 15.0 1.3 0.013 15.0 0.9 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 EIE78552.1 - 0.076 13.7 5.7 0.8 10.4 0.3 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 EIE78552.1 - 0.087 13.3 12.3 0.094 13.2 0.5 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.1 EIE78552.1 - 0.091 13.0 4.3 11 6.5 0.2 4.5 5 1 0 5 5 4 0 Tetratricopeptide repeat WWE PF02825.15 EIE78553.1 - 3.3e-06 26.4 0.0 0.00012 21.3 0.0 2.5 2 0 0 2 2 2 2 WWE domain Cofilin_ADF PF00241.15 EIE78554.1 - 3.2e-14 52.8 0.0 3.6e-14 52.7 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein PPR_3 PF13812.1 EIE78555.1 - 6.1e-13 47.9 0.3 0.00011 22.2 0.0 3.5 3 0 0 3 3 3 2 Pentatricopeptide repeat domain PPR_2 PF13041.1 EIE78555.1 - 3.1e-10 39.8 0.8 0.00071 19.4 0.2 2.6 2 0 0 2 2 2 2 PPR repeat family PPR PF01535.15 EIE78555.1 - 7.8e-08 31.7 1.5 0.00021 21.0 0.0 2.7 2 0 0 2 2 2 2 PPR repeat TPR_12 PF13424.1 EIE78555.1 - 0.0042 16.9 2.7 0.38 10.7 0.1 3.2 2 2 1 3 3 3 1 Tetratricopeptide repeat DUF2450 PF10475.4 EIE78555.1 - 0.0051 15.7 0.3 0.0074 15.2 0.2 1.4 1 1 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) DUF1045 PF06299.7 EIE78555.1 - 0.047 13.3 0.2 0.076 12.6 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1045) Ank_2 PF12796.2 EIE78555.1 - 0.07 13.4 0.2 0.37 11.1 0.0 1.9 1 1 1 2 2 2 0 Ankyrin repeats (3 copies) Bystin PF05291.6 EIE78556.1 - 4.9e-45 153.7 2.8 9.5e-23 80.5 0.3 2.4 1 1 1 2 2 2 2 Bystin Acyltransferase PF01553.16 EIE78557.1 - 1.3e-17 63.4 0.0 2.2e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Pex24p PF06398.6 EIE78558.1 - 1.3e-22 80.1 5.2 1.5e-22 79.8 3.6 1.0 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin TMEM154 PF15102.1 EIE78558.1 - 0.012 15.3 0.3 0.023 14.3 0.0 1.7 2 0 0 2 2 2 0 TMEM154 protein family DUF2534 PF10749.4 EIE78558.1 - 0.029 14.2 0.7 0.079 12.8 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2534) Arm PF00514.18 EIE78559.1 - 2.9e-20 71.2 6.2 4e-05 23.2 0.0 6.4 6 0 0 6 6 6 4 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EIE78559.1 - 1.5e-14 54.0 1.6 0.00066 19.9 0.0 5.3 1 1 3 4 4 4 3 HEAT repeats HEAT_EZ PF13513.1 EIE78559.1 - 8.1e-09 35.7 3.6 0.0099 16.3 0.0 5.8 4 1 3 7 7 7 2 HEAT-like repeat HEAT PF02985.17 EIE78559.1 - 0.00038 20.2 8.6 0.017 15.1 0.0 5.9 8 0 0 8 8 8 1 HEAT repeat Proteasom_PSMB PF10508.4 EIE78559.1 - 0.032 12.5 0.1 2 6.6 0.0 2.4 1 1 2 3 3 3 0 Proteasome non-ATPase 26S subunit Adaptin_N PF01602.15 EIE78559.1 - 0.089 11.1 0.6 3.6 5.8 0.0 2.9 2 1 2 4 4 4 0 Adaptin N terminal region IBB PF01749.15 EIE78559.1 - 0.1 12.7 5.0 0.2 11.8 3.5 1.4 1 0 0 1 1 1 0 Importin beta binding domain Glyco_hydro_81 PF03639.8 EIE78560.1 - 9.9e-90 301.4 0.0 1.2e-89 301.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 Methyltransf_23 PF13489.1 EIE78561.1 - 2.4e-11 43.6 0.0 3.5e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIE78561.1 - 1.8e-08 34.7 0.0 5e-08 33.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIE78561.1 - 8.7e-05 22.1 0.1 0.017 14.7 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIE78561.1 - 0.00081 19.8 0.0 0.016 15.6 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 EIE78561.1 - 0.0027 17.1 0.0 0.004 16.6 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.13 EIE78561.1 - 0.0034 16.5 0.0 0.041 12.9 0.0 2.0 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.10 EIE78561.1 - 0.0071 15.9 0.0 0.014 14.9 0.0 1.5 2 0 0 2 2 2 1 Hypothetical methyltransferase Methyltransf_7 PF03492.10 EIE78561.1 - 0.014 14.1 0.3 0.13 10.9 0.0 2.0 2 0 0 2 2 2 0 SAM dependent carboxyl methyltransferase MTS PF05175.9 EIE78561.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain zf-HC5HC2H_2 PF13832.1 EIE78562.1 - 2.4e-35 120.8 6.3 2.4e-35 120.8 4.4 2.6 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EIE78562.1 - 1.8e-28 98.4 3.7 1.8e-28 98.4 2.6 3.3 3 0 0 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.1 EIE78562.1 - 6.2e-15 54.2 3.3 6.2e-15 54.2 2.3 2.8 2 0 0 2 2 2 1 PHD-finger EPL1 PF10513.4 EIE78562.1 - 6.6e-13 49.2 14.3 6.6e-13 49.2 9.9 3.6 2 2 0 2 2 2 1 Enhancer of polycomb-like PHD PF00628.24 EIE78562.1 - 2.9e-10 39.6 25.5 1.4e-08 34.3 6.7 2.9 3 0 0 3 3 3 2 PHD-finger C1_1 PF00130.17 EIE78562.1 - 0.0011 18.6 1.0 0.0011 18.6 0.7 2.8 3 0 0 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) UPF0160 PF03690.8 EIE78564.1 - 1.1e-125 419.2 0.0 1.3e-125 419.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Exo_endo_phos_2 PF14529.1 EIE78566.1 - 2.4e-05 23.9 0.0 2.9e-05 23.6 0.0 1.2 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EIE78566.1 - 0.0072 16.2 0.0 0.0076 16.2 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family STN PF07660.9 EIE78566.1 - 0.11 12.1 0.1 0.22 11.0 0.0 1.6 1 0 0 1 1 1 0 Secretin and TonB N terminus short domain RRM_6 PF14259.1 EIE78567.1 - 0.027 14.4 0.0 0.065 13.2 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) HSF_DNA-bind PF00447.12 EIE78568.1 - 3.9e-30 104.0 1.8 9e-30 102.9 0.0 2.5 3 0 0 3 3 3 1 HSF-type DNA-binding LOH1CR12 PF10158.4 EIE78568.1 - 0.075 12.8 1.1 0.16 11.7 0.8 1.5 1 0 0 1 1 1 0 Tumour suppressor protein Med28 PF11594.3 EIE78568.1 - 0.1 12.8 1.1 0.23 11.7 0.8 1.5 1 0 0 1 1 1 0 Mediator complex subunit 28 Casein_kappa PF00997.13 EIE78568.1 - 0.18 11.4 8.8 0.49 10.0 6.1 1.7 1 1 0 1 1 1 0 Kappa casein Glyco_transf_22 PF03901.12 EIE78569.1 - 2.9e-25 89.1 18.4 3.6e-25 88.8 12.8 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Glutaredoxin PF00462.19 EIE78569.1 - 6.4e-15 54.8 0.0 1.2e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.1 EIE78569.1 - 0.00096 19.3 0.0 0.002 18.2 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like domain DUF836 PF05768.9 EIE78569.1 - 0.0011 19.1 0.0 0.002 18.3 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin PF00085.15 EIE78569.1 - 0.0063 16.1 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin GST_N_3 PF13417.1 EIE78569.1 - 0.03 14.5 0.0 0.085 13.0 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Xan_ur_permease PF00860.15 EIE78569.1 - 0.2 10.1 10.0 0.065 11.7 3.7 2.0 2 0 0 2 2 2 0 Permease family Arrestin_C PF02752.17 EIE78570.1 - 0.0021 18.1 3.2 0.0047 17.0 0.0 2.7 3 0 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EIE78570.1 - 0.012 15.4 0.2 0.069 12.9 0.0 2.2 2 0 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain Pex2_Pex12 PF04757.9 EIE78571.1 - 3.1e-36 124.9 4.0 4.2e-36 124.5 2.7 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region TFIID-18kDa PF02269.11 EIE78572.1 - 3.1e-29 100.6 0.6 3.8e-29 100.3 0.4 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Hat1_N PF10394.4 EIE78573.1 - 0.023 14.7 0.1 0.033 14.2 0.1 1.4 1 1 0 1 1 1 0 Histone acetyl transferase HAT1 N-terminus AAA_11 PF13086.1 EIE78574.1 - 4.1e-12 46.1 0.0 1.2e-11 44.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain TORC_M PF12885.2 EIE78574.1 - 0.067 12.9 1.7 0.13 12.0 1.2 1.4 1 0 0 1 1 1 0 Transducer of regulated CREB activity middle domain AAA_19 PF13245.1 EIE78574.1 - 0.088 12.5 0.1 0.57 9.9 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain DEAD PF00270.24 EIE78574.1 - 0.089 12.2 0.2 0.3 10.5 0.0 1.9 2 0 0 2 2 2 0 DEAD/DEAH box helicase DUF3186 PF11382.3 EIE78576.1 - 0.13 11.3 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3186) DUF4535 PF15054.1 EIE78576.1 - 1.3 8.4 5.5 0.62 9.5 1.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4535) Ank_2 PF12796.2 EIE78577.1 - 7.9e-12 45.3 0.3 2.4e-06 27.7 0.2 3.0 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EIE78577.1 - 1.1e-08 35.3 0.2 0.00038 20.8 0.0 3.7 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIE78577.1 - 9.8e-08 31.5 0.3 0.0053 16.8 0.0 4.2 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.25 EIE78577.1 - 1.1e-06 28.1 2.4 0.0058 16.3 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.8 EIE78577.1 - 0.00077 19.0 0.8 0.00077 19.0 0.6 3.4 3 1 0 3 3 3 1 KilA-N domain Ank_5 PF13857.1 EIE78577.1 - 0.0045 17.1 0.1 0.92 9.8 0.0 3.5 3 1 0 3 3 3 1 Ankyrin repeats (many copies) DUF1967 PF09269.6 EIE78577.1 - 0.019 14.6 0.5 22 4.8 0.2 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1967) Cob_adeno_trans PF01923.13 EIE78577.1 - 0.56 9.9 8.3 1.6 8.5 1.9 3.2 3 0 0 3 3 3 0 Cobalamin adenosyltransferase COG2 PF06148.6 EIE78577.1 - 0.98 9.2 13.4 0.17 11.7 4.1 2.8 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 FlaC_arch PF05377.6 EIE78577.1 - 1.3 9.0 12.5 0.38 10.6 2.6 3.2 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) SPX PF03105.14 EIE78578.1 - 9.4e-15 55.1 11.5 6.5e-09 35.9 0.1 3.0 2 1 1 3 3 3 2 SPX domain HAD PF12710.2 EIE78578.1 - 2.4e-13 50.6 0.1 7.7e-13 49.0 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EIE78578.1 - 7.5e-11 42.0 2.8 1.2e-09 38.1 0.0 3.0 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EIE78578.1 - 5.4e-09 36.7 0.5 7.3e-08 33.0 0.3 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase ACT_6 PF13740.1 EIE78578.1 - 2.7e-07 30.1 0.0 9.1e-07 28.5 0.0 2.0 1 0 0 1 1 1 1 ACT domain Put_Phosphatase PF06888.7 EIE78578.1 - 0.00041 19.6 0.0 0.22 10.6 0.0 2.5 2 0 0 2 2 2 2 Putative Phosphatase HAD_2 PF13419.1 EIE78578.1 - 0.0067 16.6 0.0 0.039 14.1 0.0 2.3 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase DUF705 PF05152.7 EIE78578.1 - 0.027 13.4 0.3 0.085 11.8 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF705) RNB PF00773.14 EIE78579.1 - 4.5e-80 269.3 2.1 4.5e-80 269.3 1.5 1.8 2 0 0 2 2 2 1 RNB domain Ribosomal_S3_C PF00189.15 EIE78580.1 - 3.5e-09 36.7 0.1 6.3e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain VAR1 PF05316.7 EIE78580.1 - 0.016 13.8 0.1 0.087 11.4 0.0 2.0 1 1 0 1 1 1 0 Mitochondrial ribosomal protein (VAR1) PDZ_1 PF12812.2 EIE78581.1 - 4.6e-22 77.6 0.0 9.1e-16 57.5 0.0 2.9 2 0 0 2 2 2 2 PDZ-like domain PDZ_2 PF13180.1 EIE78581.1 - 1.1e-13 50.8 0.0 0.00053 19.8 0.0 4.6 4 0 0 4 4 4 3 PDZ domain Trypsin_2 PF13365.1 EIE78581.1 - 2e-08 34.2 0.0 5.3e-07 29.6 0.0 2.9 3 0 0 3 3 3 1 Trypsin-like peptidase domain PDZ PF00595.19 EIE78581.1 - 5.7e-07 29.6 1.3 0.02 15.0 0.0 3.9 4 0 0 4 4 4 3 PDZ domain (Also known as DHR or GLGF) Plasmodium_Vir PF05795.6 EIE78582.1 - 0.0017 17.6 4.4 0.0026 17.0 3.0 1.2 1 0 0 1 1 1 1 Plasmodium vivax Vir protein Herpes_gE PF02480.11 EIE78582.1 - 0.0048 15.2 0.2 0.011 14.0 0.0 1.5 1 1 0 1 1 1 1 Alphaherpesvirus glycoprotein E Pox_A14 PF05767.7 EIE78582.1 - 0.015 15.2 0.0 0.035 14.0 0.0 1.6 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 MSC PF09402.5 EIE78582.1 - 0.033 12.8 0.0 0.042 12.5 0.0 1.2 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain TMEM51 PF15345.1 EIE78582.1 - 0.074 12.7 0.1 0.074 12.7 0.1 1.9 1 1 1 2 2 2 0 Transmembrane protein 51 Macoilin PF09726.4 EIE78582.1 - 0.45 8.7 5.2 2.5 6.2 4.1 1.8 2 0 0 2 2 2 0 Transmembrane protein HA2 PF04408.18 EIE78583.1 - 1.7e-20 72.9 0.0 1.7e-20 72.9 0.0 2.0 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EIE78583.1 - 1.2e-12 47.4 0.0 3.6e-12 45.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EIE78583.1 - 1.2e-09 37.9 0.3 2.3e-09 36.9 0.2 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.11 EIE78583.1 - 4.5e-07 29.6 0.0 4.5e-07 29.6 0.0 1.9 2 0 0 2 2 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.1 EIE78583.1 - 1.4e-05 25.2 0.1 3.8e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 EIE78583.1 - 0.00018 20.5 0.0 0.00045 19.2 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_23 PF13476.1 EIE78583.1 - 0.0047 17.2 3.2 0.49 10.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 EIE78583.1 - 0.0051 17.3 1.7 0.019 15.4 0.0 2.7 3 0 0 3 3 3 1 Miro-like protein SRP54 PF00448.17 EIE78583.1 - 0.016 14.6 0.4 0.016 14.6 0.3 2.1 2 1 0 2 2 1 0 SRP54-type protein, GTPase domain ResIII PF04851.10 EIE78583.1 - 0.018 14.8 5.0 0.26 11.0 0.0 2.9 2 1 0 3 3 3 0 Type III restriction enzyme, res subunit PhoH PF02562.11 EIE78583.1 - 0.018 14.2 0.0 0.13 11.5 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA_14 PF13173.1 EIE78583.1 - 0.075 12.9 0.1 0.62 9.9 0.1 2.4 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EIE78583.1 - 0.078 12.7 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Arch_ATPase PF01637.13 EIE78583.1 - 0.081 12.6 0.1 0.081 12.6 0.1 1.9 2 0 0 2 2 1 0 Archaeal ATPase AAA_11 PF13086.1 EIE78583.1 - 1 8.8 9.5 7.4 6.0 0.0 3.7 3 1 0 4 4 4 0 AAA domain ABC_tran PF00005.22 EIE78583.1 - 1.5 9.1 4.7 0.44 10.8 0.2 2.3 2 1 1 3 3 2 0 ABC transporter PEMT PF04191.8 EIE78584.1 - 8.8e-35 119.0 3.2 1.7e-34 118.1 2.2 1.5 1 0 0 1 1 1 1 Phospholipid methyltransferase DUF4605 PF15378.1 EIE78584.1 - 0.2 11.4 2.0 0.57 9.9 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4605) ABC_tran PF00005.22 EIE78585.1 - 3.4e-45 153.7 0.0 2.1e-22 79.9 0.0 3.8 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EIE78585.1 - 1.6e-15 57.8 0.0 0.0048 16.8 0.0 4.3 4 0 0 4 4 4 4 AAA domain SMC_N PF02463.14 EIE78585.1 - 1.3e-13 50.7 0.0 0.0039 16.4 0.0 4.4 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EIE78585.1 - 1.4e-08 35.5 0.2 0.0011 19.8 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.1 EIE78585.1 - 9.5e-08 31.4 0.1 0.01 15.3 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 EIE78585.1 - 2.3e-07 31.0 0.0 0.02 15.0 0.0 4.2 5 0 0 5 5 4 2 AAA domain AAA_28 PF13521.1 EIE78585.1 - 5.8e-07 29.6 0.0 0.038 13.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EIE78585.1 - 7.5e-07 28.4 0.0 0.0028 16.8 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Miro PF08477.8 EIE78585.1 - 9.3e-07 29.3 0.0 0.069 13.6 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein MMR_HSR1 PF01926.18 EIE78585.1 - 2.6e-06 27.3 0.0 0.017 15.0 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase MobB PF03205.9 EIE78585.1 - 3.1e-06 26.9 0.1 0.14 11.8 0.0 3.3 3 0 0 3 3 3 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 EIE78585.1 - 4.1e-06 26.4 0.1 0.54 9.6 0.0 3.6 4 0 0 4 4 4 2 AAA-like domain Chromo PF00385.19 EIE78585.1 - 5.3e-06 26.0 1.3 2.2e-05 24.0 0.2 2.4 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain ArgK PF03308.11 EIE78585.1 - 6.9e-06 25.0 0.4 0.03 13.1 0.0 2.9 3 0 0 3 3 3 2 ArgK protein AAA PF00004.24 EIE78585.1 - 8.4e-06 26.0 0.1 0.08 13.1 0.0 3.4 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.1 EIE78585.1 - 1e-05 25.3 0.0 0.026 14.4 0.0 3.2 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.17 EIE78585.1 - 1.9e-05 24.7 0.0 0.35 11.0 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_16 PF13191.1 EIE78585.1 - 3.2e-05 23.9 3.2 0.048 13.6 0.0 3.8 3 1 0 3 3 3 2 AAA ATPase domain AAA_18 PF13238.1 EIE78585.1 - 6.6e-05 23.2 0.1 0.22 11.8 0.0 2.9 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 EIE78585.1 - 7e-05 22.5 0.0 0.11 12.1 0.0 2.7 2 0 0 2 2 2 2 NACHT domain DUF815 PF05673.8 EIE78585.1 - 7.7e-05 21.7 0.0 0.16 10.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_15 PF13175.1 EIE78585.1 - 7.8e-05 21.8 0.0 1.4 7.8 0.0 3.3 3 0 0 3 3 3 2 AAA ATPase domain AAA_33 PF13671.1 EIE78585.1 - 7.8e-05 22.5 0.0 0.44 10.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 EIE78585.1 - 0.00048 20.5 10.3 0.13 12.6 0.4 3.5 3 1 0 3 3 3 2 AAA domain PduV-EutP PF10662.4 EIE78585.1 - 0.00051 19.5 0.0 0.67 9.4 0.0 2.8 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation ATP-synt_ab PF00006.20 EIE78585.1 - 0.00054 19.5 0.0 0.19 11.2 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_14 PF13173.1 EIE78585.1 - 0.00055 19.8 0.0 0.4 10.5 0.0 2.9 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EIE78585.1 - 0.001 18.2 1.4 3.2 6.8 0.0 4.0 4 0 0 4 4 4 1 Zeta toxin Arch_ATPase PF01637.13 EIE78585.1 - 0.0031 17.2 0.0 1.3 8.7 0.0 2.7 2 0 0 2 2 2 1 Archaeal ATPase Dynamin_N PF00350.18 EIE78585.1 - 0.0036 17.1 0.4 0.6 9.9 0.0 3.0 3 0 0 3 3 2 1 Dynamin family AAA_13 PF13166.1 EIE78585.1 - 0.0059 15.1 0.6 4.6 5.5 0.0 3.3 4 0 0 4 4 4 0 AAA domain DUF87 PF01935.12 EIE78585.1 - 0.0066 16.2 4.8 0.52 10.0 0.0 3.6 4 0 0 4 4 3 1 Domain of unknown function DUF87 AAA_25 PF13481.1 EIE78585.1 - 0.033 13.6 0.0 8.9 5.6 0.0 2.9 3 0 0 3 3 2 0 AAA domain MutS_V PF00488.16 EIE78585.1 - 0.037 13.4 0.0 7.9 5.8 0.0 2.3 2 0 0 2 2 2 0 MutS domain V Viral_helicase1 PF01443.13 EIE78585.1 - 0.037 13.5 0.0 0.7 9.3 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase PRK PF00485.13 EIE78585.1 - 0.053 13.0 0.0 2.6 7.5 0.0 2.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family HEAT PF02985.17 EIE78585.1 - 0.1 12.6 0.4 2.6 8.3 0.0 3.5 3 0 0 3 3 2 0 HEAT repeat Adeno_IVa2 PF02456.10 EIE78585.1 - 0.15 10.6 0.0 5.8 5.4 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein RA PF00788.18 EIE78586.1 - 4.9e-13 49.3 0.0 7.9e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_2 PF07647.12 EIE78586.1 - 2.2e-12 46.6 0.4 1.2e-11 44.2 0.1 2.1 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EIE78586.1 - 8.1e-09 35.5 0.9 5.2e-08 32.9 0.3 2.2 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) IncA PF04156.9 EIE78586.1 - 0.021 14.4 0.6 0.032 13.8 0.4 1.3 1 0 0 1 1 1 0 IncA protein Mnd1 PF03962.10 EIE78586.1 - 0.036 13.7 3.8 0.067 12.8 2.7 1.4 1 0 0 1 1 1 0 Mnd1 family SAM_PNT PF02198.11 EIE78586.1 - 0.048 13.4 0.2 0.081 12.6 0.1 1.4 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Prefoldin PF02996.12 EIE78586.1 - 0.074 12.7 1.9 1.1 8.8 0.4 2.3 2 0 0 2 2 2 0 Prefoldin subunit Phlebovirus_NSM PF07246.6 EIE78586.1 - 0.075 12.1 4.1 0.13 11.4 2.9 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M V_ATPase_I PF01496.14 EIE78586.1 - 0.15 9.9 0.9 0.2 9.4 0.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIC PF04977.10 EIE78586.1 - 0.33 10.4 3.2 1 8.8 0.7 2.7 2 1 0 2 2 2 0 Septum formation initiator DUF904 PF06005.7 EIE78586.1 - 4.7 7.5 9.5 11 6.4 3.9 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF904) OrfB_Zn_ribbon PF07282.6 EIE78588.1 - 0.015 14.9 1.7 1.2 8.8 0.3 2.3 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Abhydrolase_5 PF12695.2 EIE78590.1 - 1.2e-11 44.5 0.0 1.6e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIE78590.1 - 1.4e-09 38.2 0.0 1e-05 25.5 0.0 2.0 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EIE78590.1 - 6.2e-08 32.1 0.0 1.2e-07 31.1 0.0 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family BAAT_C PF08840.6 EIE78590.1 - 0.00046 19.9 0.0 0.014 15.1 0.0 2.1 1 1 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal AXE1 PF05448.7 EIE78590.1 - 0.00071 18.1 0.0 0.14 10.6 0.0 2.1 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.11 EIE78590.1 - 0.00072 19.0 0.1 0.032 13.6 0.0 2.0 1 1 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.15 EIE78590.1 - 0.007 15.9 0.0 0.18 11.3 0.0 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.15 EIE78590.1 - 0.021 14.2 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Acetyltransf_1 PF00583.19 EIE78591.1 - 0.00035 20.5 0.0 0.00058 19.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EIE78591.1 - 0.0051 16.9 0.1 0.0088 16.1 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EIE78591.1 - 0.0093 15.9 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EIE78591.1 - 0.033 13.9 0.0 0.064 13.0 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_3 PF13302.1 EIE78591.1 - 0.1 12.7 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ribosomal_S27e PF01667.12 EIE78592.1 - 7.3e-26 89.4 5.1 7.8e-26 89.3 3.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S27 TF_Zn_Ribbon PF08271.7 EIE78592.1 - 0.00031 19.9 2.5 0.00039 19.6 1.7 1.2 1 0 0 1 1 1 1 TFIIB zinc-binding IBR PF01485.16 EIE78592.1 - 0.0076 16.1 2.3 0.008 16.0 1.6 1.2 1 0 0 1 1 1 1 IBR domain zf-ribbon_3 PF13248.1 EIE78592.1 - 0.032 13.4 2.4 1.5 8.1 0.3 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2HC5 PF06221.8 EIE78592.1 - 0.034 13.9 1.1 0.034 13.9 0.8 1.6 1 1 1 2 2 2 0 Putative zinc finger motif, C2HC5-type zinc_ribbon_4 PF13717.1 EIE78592.1 - 0.061 13.0 2.6 3.2 7.5 1.8 2.4 1 1 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EIE78592.1 - 0.091 12.3 2.8 5 6.7 1.9 2.4 1 1 0 1 1 1 0 zinc-ribbon domain PhnA_Zn_Ribbon PF08274.7 EIE78592.1 - 0.11 12.2 0.6 0.22 11.3 0.4 1.4 1 0 0 1 1 1 0 PhnA Zinc-Ribbon TFIIS_C PF01096.13 EIE78592.1 - 0.2 11.3 1.9 1.1 8.9 0.0 2.2 1 1 1 2 2 2 0 Transcription factor S-II (TFIIS) FYVE PF01363.16 EIE78592.1 - 0.22 11.4 3.1 0.22 11.4 2.2 1.1 1 0 0 1 1 1 0 FYVE zinc finger RecR PF02132.10 EIE78592.1 - 0.27 10.6 3.8 1.2 8.6 0.6 2.2 2 0 0 2 2 2 0 RecR protein Prok-RING_1 PF14446.1 EIE78592.1 - 0.28 10.9 3.0 0.36 10.5 2.1 1.4 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 OrfB_Zn_ribbon PF07282.6 EIE78592.1 - 0.49 10.0 2.7 0.57 9.8 1.9 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Auto_anti-p27 PF06677.7 EIE78592.1 - 0.5 10.1 0.2 0.5 10.1 0.2 2.0 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-NADH-PPase PF09297.6 EIE78592.1 - 1 8.9 0.1 1 8.9 0.0 2.4 2 1 1 3 3 3 0 NADH pyrophosphatase zinc ribbon domain Zn_Tnp_IS1 PF03811.8 EIE78592.1 - 1.3 8.6 4.0 7.3 6.1 2.8 2.1 1 1 0 1 1 1 0 InsA N-terminal domain UPF0547 PF10571.4 EIE78592.1 - 1.7 8.3 4.2 4.9 6.9 0.2 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-LSD1 PF06943.7 EIE78592.1 - 1.8 8.2 5.7 2.9 7.5 1.6 2.3 2 0 0 2 2 2 0 LSD1 zinc finger Tnp_zf-ribbon_2 PF13842.1 EIE78592.1 - 1.9 8.9 6.2 0.45 10.9 1.9 1.8 2 1 0 2 2 1 0 DDE_Tnp_1-like zinc-ribbon zf-C3HC4_3 PF13920.1 EIE78592.1 - 2 8.1 5.4 3.7 7.3 3.7 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DZR PF12773.2 EIE78592.1 - 2.2 8.1 5.0 9.1 6.1 3.5 2.0 1 1 0 1 1 1 0 Double zinc ribbon MFS_1 PF07690.11 EIE78593.1 - 1.6e-36 125.7 35.4 1.6e-36 125.7 24.6 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.15 EIE78593.1 - 2.8e-07 28.9 0.7 2.8e-07 28.9 0.5 2.2 3 0 0 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family MFS_2 PF13347.1 EIE78593.1 - 1.1e-06 27.3 4.2 1.1e-06 27.3 2.9 2.2 1 1 0 2 2 2 2 MFS/sugar transport protein DUF3353 PF11833.3 EIE78593.1 - 2.5 7.5 11.9 0.46 9.9 2.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3353) DUF3295 PF11702.3 EIE78596.1 - 0.096 11.6 1.0 0.11 11.4 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) RVT_1 PF00078.22 EIE78597.1 - 1.5e-09 37.5 0.1 1.7e-09 37.3 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phosphoesterase PF04185.9 EIE78598.1 - 4.6e-31 108.3 2.4 3.1e-30 105.6 1.7 1.9 1 1 0 1 1 1 1 Phosphoesterase family MIF4G_like PF09088.6 EIE78599.1 - 4.7e-59 199.0 0.3 9.9e-59 197.9 0.2 1.6 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.6 EIE78599.1 - 2.2e-49 167.9 9.7 3.7e-49 167.2 6.7 1.4 1 0 0 1 1 1 1 MIF4G like MIF4G PF02854.14 EIE78599.1 - 2.4e-12 46.7 1.6 7.7e-12 45.0 0.1 2.4 2 0 0 2 2 2 1 MIF4G domain DnaJ-X PF14308.1 EIE78599.1 - 0.029 13.6 2.1 0.054 12.7 1.4 1.4 1 0 0 1 1 1 0 X-domain of DnaJ-containing Protamine_P2 PF00841.14 EIE78600.1 - 0.39 11.2 2.4 0.89 10.1 1.7 1.6 1 0 0 1 1 1 0 Sperm histone P2 UCH PF00443.24 EIE78601.1 - 1.5e-27 96.4 1.2 1.6e-26 93.0 0.0 2.7 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EIE78601.1 - 4.5e-11 42.7 0.3 8.6e-11 41.8 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase SEP PF08059.8 EIE78601.1 - 0.15 12.3 0.5 0.96 9.8 0.1 2.4 2 0 0 2 2 2 0 SEP domain DUF2373 PF10180.4 EIE78601.1 - 0.16 11.5 0.8 0.36 10.3 0.6 1.6 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) MATH PF00917.21 EIE78602.1 - 1.5e-08 34.8 0.0 2.5e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 MATH domain AHSA1 PF08327.6 EIE78602.1 - 0.016 15.2 0.1 0.021 14.9 0.0 1.2 1 0 0 1 1 1 0 Activator of Hsp90 ATPase homolog 1-like protein Rep_fac_C PF08542.6 EIE78604.1 - 4.5e-19 68.2 0.0 1.1e-18 66.9 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EIE78604.1 - 1.8e-11 44.0 0.1 3e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 EIE78604.1 - 2.6e-07 30.8 0.1 5.2e-07 29.9 0.1 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta PF06144.8 EIE78604.1 - 5e-05 22.8 0.2 0.0001 21.8 0.1 1.5 2 0 0 2 2 2 1 DNA polymerase III, delta subunit DEAD PF00270.24 EIE78604.1 - 0.0054 16.2 0.0 0.01 15.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EIE78604.1 - 0.016 15.3 0.0 0.046 13.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain zf-DNA_Pol PF08996.5 EIE78604.1 - 0.027 13.8 0.2 0.048 13.0 0.2 1.4 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger TPR_6 PF13174.1 EIE78604.1 - 0.041 14.3 1.7 7.6 7.2 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat SNF2_N PF00176.18 EIE78604.1 - 0.042 12.6 0.1 0.064 12.0 0.1 1.3 1 1 0 1 1 1 0 SNF2 family N-terminal domain BrkDBD PF09607.5 EIE78604.1 - 0.05 13.1 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 Brinker DNA-binding domain Elong_Iki1 PF10483.4 EIE78604.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.3 2 0 0 2 2 2 0 Elongator subunit Iki1 GATA PF00320.22 EIE78605.1 - 7e-17 60.4 5.6 1.7e-16 59.2 3.9 1.7 1 0 0 1 1 1 1 GATA zinc finger NOB1_Zn_bind PF08772.6 EIE78605.1 - 0.05 13.4 0.2 0.14 12.0 0.1 1.8 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like zf-3CxxC PF13695.1 EIE78605.1 - 0.48 10.6 4.2 0.71 10.1 1.9 2.3 1 1 1 2 2 2 0 Zinc-binding domain Methyltransf_23 PF13489.1 EIE78607.1 - 0.0001 22.0 0.0 0.00016 21.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIE78607.1 - 0.00054 20.3 0.0 0.0014 19.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain EVI2A PF05399.6 EIE78607.1 - 0.18 11.0 5.7 0.24 10.6 3.9 1.2 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) UPF1_Zn_bind PF09416.5 EIE78609.1 - 2.3e-75 251.3 5.6 2.3e-75 251.3 3.9 1.9 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.1 EIE78609.1 - 1e-57 194.7 0.0 1.9e-57 193.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EIE78609.1 - 1.9e-55 187.9 1.7 3.1e-55 187.3 1.2 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EIE78609.1 - 1e-14 54.0 0.1 3e-14 52.5 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EIE78609.1 - 1.4e-12 47.6 0.1 1.7e-11 44.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 EIE78609.1 - 1.5e-07 31.3 0.0 2.9e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 EIE78609.1 - 5.8e-06 26.0 0.0 0.093 12.2 0.0 2.8 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 EIE78609.1 - 1.7e-05 24.0 0.1 0.00026 20.0 0.0 2.8 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.9 EIE78609.1 - 0.00029 20.4 0.1 0.00067 19.3 0.0 1.6 1 1 0 1 1 1 1 Helicase UvrD-helicase PF00580.16 EIE78609.1 - 0.00034 20.0 0.0 0.0081 15.4 0.0 2.6 2 1 0 3 3 3 1 UvrD/REP helicase N-terminal domain DEAD PF00270.24 EIE78609.1 - 0.00094 18.7 0.1 0.0065 15.9 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Ribosomal_S13_N PF08069.7 EIE78609.1 - 0.0037 17.0 0.0 0.0083 15.9 0.0 1.6 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain SRP54 PF00448.17 EIE78609.1 - 0.0077 15.6 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_25 PF13481.1 EIE78609.1 - 0.0095 15.3 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EIE78609.1 - 0.025 14.7 0.0 0.067 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain SNF2_N PF00176.18 EIE78609.1 - 0.031 13.0 0.0 0.055 12.2 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain ArsA_ATPase PF02374.10 EIE78609.1 - 0.035 13.1 0.0 0.061 12.3 0.0 1.3 1 0 0 1 1 1 0 Anion-transporting ATPase AAA_16 PF13191.1 EIE78609.1 - 0.035 14.0 0.1 0.066 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_10 PF12846.2 EIE78609.1 - 0.063 12.7 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA PF00004.24 EIE78609.1 - 0.11 12.7 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) KaiC PF06745.8 EIE78609.1 - 0.11 11.5 0.0 0.33 10.0 0.0 1.7 2 0 0 2 2 2 0 KaiC PhoH PF02562.11 EIE78609.1 - 0.13 11.4 0.0 0.34 10.1 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein Methyltransf_28 PF02636.12 EIE78611.1 - 1.2e-64 218.1 0.0 1.3e-42 145.9 0.0 2.1 1 1 1 2 2 2 2 Putative S-adenosyl-L-methionine-dependent methyltransferase OPT PF03169.10 EIE78612.1 - 1e-73 248.8 23.7 1.1e-73 248.6 16.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DDE_3 PF13358.1 EIE78614.1 - 8e-08 32.1 0.0 1.2e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-RVT PF13966.1 EIE78615.1 - 1.1e-05 25.5 2.0 1.2e-05 25.5 0.1 1.9 2 1 0 2 2 2 1 zinc-binding in reverse transcriptase Ima1_N PF09779.4 EIE78615.1 - 0.0082 16.6 0.1 0.014 15.9 0.1 1.4 1 0 0 1 1 1 1 Ima1 N-terminal domain DUF1777 PF08648.7 EIE78616.1 - 5.6e-28 97.8 2.6 5.7e-28 97.8 1.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1777) SMAP PF15477.1 EIE78616.1 - 0.086 13.1 1.2 0.11 12.8 0.8 1.3 1 1 0 1 1 1 0 Small acidic protein family Pro_isomerase PF00160.16 EIE78617.1 - 9.4e-48 162.3 0.2 2.6e-47 160.9 0.1 1.7 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 EIE78617.1 - 3.8e-13 48.8 0.0 1.6e-12 46.8 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE78617.1 - 3e-09 36.7 0.0 4.1e-08 33.0 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE78617.1 - 2.4e-08 33.7 0.0 4.2e-07 29.6 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Aa_trans PF01490.13 EIE78618.1 - 2.3e-39 135.0 12.4 2.6e-39 134.8 8.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EIE78618.1 - 0.00011 21.1 1.0 0.00011 21.1 0.7 2.2 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family AzlD PF05437.7 EIE78618.1 - 0.012 15.4 0.6 0.012 15.4 0.4 3.0 3 1 1 4 4 4 0 Branched-chain amino acid transport protein (AzlD) HTH_29 PF13551.1 EIE78619.1 - 0.00079 19.5 0.0 0.00094 19.3 0.0 1.2 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EIE78619.1 - 0.0008 18.9 0.1 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.1 EIE78619.1 - 0.032 14.2 0.1 0.058 13.4 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HisK_N PF09385.5 EIE78619.1 - 0.075 12.6 0.2 0.26 10.8 0.0 1.9 1 1 1 2 2 2 0 Histidine kinase N terminal HTH_32 PF13565.1 EIE78619.1 - 0.092 13.5 0.0 0.15 12.8 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain Glyco_hydro_45 PF02015.11 EIE78620.1 - 4.8e-86 287.9 22.1 4.8e-86 287.9 15.3 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 45 CBM_1 PF00734.13 EIE78620.1 - 5e-14 51.6 10.7 5e-14 51.6 7.4 2.8 2 0 0 2 2 2 1 Fungal cellulose binding domain HPHLAWLY PF14925.1 EIE78620.1 - 0.14 10.1 3.7 0.2 9.6 2.6 1.1 1 0 0 1 1 1 0 Domain of unknown function RVT_1 PF00078.22 EIE78622.1 - 3.6e-08 33.0 0.0 7.9e-08 31.9 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_3 PF13358.1 EIE78623.1 - 0.072 12.8 0.0 0.089 12.5 0.0 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease PRP3 PF08572.5 EIE78624.1 - 2.4e-70 236.4 12.4 2.4e-70 236.4 8.6 1.8 2 0 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) Ribosomal_L44 PF00935.14 EIE78625.1 - 9.7e-36 121.6 10.0 1.3e-35 121.1 6.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L44 Ribosomal_L33 PF00471.15 EIE78625.1 - 4.3 7.6 8.9 3.4 7.9 1.2 2.7 2 1 0 2 2 2 0 Ribosomal protein L33 RPE65 PF03055.10 EIE78626.1 - 1.8e-92 310.4 0.0 2.4e-92 310.0 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein DnaJ PF00226.26 EIE78627.1 - 1.6e-24 85.4 3.6 2.4e-24 84.8 2.5 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EIE78627.1 - 8.7e-21 73.6 2.0 2.1e-19 69.2 0.1 3.1 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EIE78627.1 - 4.1e-17 61.9 16.1 7.5e-17 61.1 11.2 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EIE78627.1 - 0.00026 20.6 1.5 0.077 12.6 0.0 2.2 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family Lar_restr_allev PF14354.1 EIE78627.1 - 0.97 9.7 8.3 28 5.1 0.1 3.3 1 1 1 2 2 2 0 Restriction alleviation protein Lar Amidohydro_4 PF13147.1 EIE78628.1 - 6.7e-23 82.0 4.0 1.9e-21 77.3 0.7 3.7 3 1 0 3 3 3 1 Amidohydrolase Amidohydro_1 PF01979.15 EIE78628.1 - 6.6e-16 58.8 0.4 2.7e-13 50.3 0.2 3.3 2 1 0 2 2 2 1 Amidohydrolase family Amidohydro_5 PF13594.1 EIE78628.1 - 9.6e-16 57.3 0.2 2.4e-12 46.4 0.1 2.7 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_3 PF07969.6 EIE78628.1 - 1e-11 44.7 0.1 6.7e-09 35.4 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family VWA_2 PF13519.1 EIE78629.1 - 5.4e-15 55.9 0.2 5.4e-15 55.9 0.1 1.8 2 1 0 2 2 2 1 von Willebrand factor type A domain UIM PF02809.15 EIE78629.1 - 1.2e-08 33.8 30.7 0.00051 19.3 1.3 5.0 5 0 0 5 5 5 3 Ubiquitin interaction motif Ssl1 PF04056.9 EIE78629.1 - 2.2e-07 30.6 2.3 2.5e-07 30.4 0.1 2.0 2 1 1 3 3 3 1 Ssl1-like VWA PF00092.23 EIE78629.1 - 6.2e-05 22.7 0.4 0.00013 21.7 0.3 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF3549 PF12069.3 EIE78629.1 - 0.11 11.2 2.0 0.99 8.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3549) Fip1 PF05182.8 EIE78632.1 - 4.1e-24 83.5 0.8 7.2e-24 82.7 0.5 1.4 1 0 0 1 1 1 1 Fip1 motif Daxx PF03344.10 EIE78632.1 - 9.2 4.6 25.9 0.027 12.9 11.4 1.5 2 0 0 2 2 2 0 Daxx Family Phosphoesterase PF04185.9 EIE78634.1 - 3.5e-29 102.1 2.8 7.3e-28 97.8 1.9 2.1 1 1 0 1 1 1 1 Phosphoesterase family DUF806 PF05657.6 EIE78634.1 - 0.026 14.5 0.2 2 8.4 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF806) Glyco_hydro_16 PF00722.16 EIE78636.1 - 8.1e-29 100.2 0.2 1e-28 99.8 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 HMG_box PF00505.14 EIE78637.1 - 5.6e-17 61.7 0.4 5.6e-17 61.7 0.3 2.4 3 0 0 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EIE78637.1 - 4.5e-11 42.9 0.2 4.5e-11 42.9 0.2 1.8 2 0 0 2 2 2 1 HMG-box domain DUF4600 PF15372.1 EIE78637.1 - 0.017 15.3 2.1 0.017 15.3 1.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4600) SlyX PF04102.7 EIE78637.1 - 0.036 14.4 0.6 0.25 11.7 0.3 2.2 2 0 0 2 2 2 0 SlyX HALZ PF02183.13 EIE78637.1 - 0.04 13.6 1.7 0.13 12.0 1.2 1.9 1 0 0 1 1 1 0 Homeobox associated leucine zipper WXG100 PF06013.7 EIE78637.1 - 0.058 13.3 0.0 1.4 8.9 0.0 2.1 2 0 0 2 2 2 0 Proteins of 100 residues with WXG Cep57_CLD_2 PF14197.1 EIE78637.1 - 0.095 12.6 4.6 0.21 11.5 3.2 1.6 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 CASP_C PF08172.7 EIE78637.1 - 0.14 11.1 2.0 0.16 10.9 1.4 1.2 1 0 0 1 1 1 0 CASP C terminal XhlA PF10779.4 EIE78637.1 - 0.19 11.6 2.5 0.62 10.0 1.7 1.9 1 0 0 1 1 1 0 Haemolysin XhlA Tox-REase-2 PF15646.1 EIE78637.1 - 0.22 11.4 3.2 1.1 9.0 0.2 2.4 2 0 0 2 2 2 0 Restriction endonuclease fold toxin 2 NEMO PF11577.3 EIE78637.1 - 0.23 11.2 11.6 0.081 12.6 4.1 2.4 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO CENP-Q PF13094.1 EIE78637.1 - 0.41 10.6 4.5 0.82 9.6 3.1 1.4 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit TPR_MLP1_2 PF07926.7 EIE78637.1 - 1.4 8.6 7.1 0.89 9.3 2.2 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF972 PF06156.8 EIE78637.1 - 3 8.2 8.0 1.4 9.3 2.8 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF972) DDE_3 PF13358.1 EIE78639.1 - 0.042 13.5 0.1 0.044 13.5 0.0 1.3 1 1 0 1 1 1 0 DDE superfamily endonuclease DUF204 PF02659.10 EIE78639.1 - 0.082 13.0 0.1 0.085 12.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF CS PF04969.11 EIE78640.1 - 9.7e-09 35.6 0.2 1.7e-08 34.9 0.1 1.4 1 0 0 1 1 1 1 CS domain NT-C2 PF10358.4 EIE78640.1 - 0.061 12.8 0.7 0.081 12.4 0.5 1.2 1 0 0 1 1 1 0 N-terminal C2 in EEIG1 and EHBP1 proteins Ribosomal_S3Ae PF01015.13 EIE78641.1 - 4.5e-79 264.3 7.0 5.3e-79 264.0 4.8 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Spt4 PF06093.8 EIE78641.1 - 0.11 12.3 0.3 0.94 9.4 0.0 2.3 2 0 0 2 2 2 0 Spt4/RpoE2 zinc finger DUF496 PF04363.7 EIE78641.1 - 4.1 7.2 6.4 3.8 7.4 0.4 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF496) PGAP1 PF07819.8 EIE78642.1 - 1.3e-75 253.9 0.1 1.6e-75 253.5 0.0 1.1 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EIE78642.1 - 4.5e-05 23.2 0.0 8.8e-05 22.2 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 EIE78642.1 - 5.2e-05 22.6 0.0 0.00013 21.3 0.0 1.6 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 EIE78642.1 - 7.2e-05 22.7 0.0 0.00014 21.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIE78642.1 - 0.00061 19.4 0.0 0.0014 18.2 0.0 1.6 1 1 0 2 2 2 1 alpha/beta hydrolase fold LCAT PF02450.10 EIE78642.1 - 0.0021 17.0 0.0 0.0038 16.2 0.0 1.3 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF915 PF06028.6 EIE78642.1 - 0.0039 16.3 0.0 0.025 13.6 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) DUF2305 PF10230.4 EIE78642.1 - 0.0056 16.1 0.0 0.0097 15.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) DUF2974 PF11187.3 EIE78642.1 - 0.028 13.7 0.0 0.046 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Lipase_3 PF01764.20 EIE78642.1 - 0.03 13.9 0.0 0.056 13.0 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) ABC_tran PF00005.22 EIE78643.1 - 2.4e-50 170.3 0.0 2.1e-26 92.8 0.0 3.3 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EIE78643.1 - 1.1e-19 71.5 1.7 4.7e-05 23.4 0.0 4.5 3 1 1 4 4 4 4 AAA domain SMC_N PF02463.14 EIE78643.1 - 1.8e-13 50.2 1.1 0.027 13.6 0.0 4.5 3 1 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EIE78643.1 - 1.9e-08 33.7 0.1 0.0037 16.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_33 PF13671.1 EIE78643.1 - 7.6e-08 32.3 0.1 0.048 13.5 0.0 3.6 3 0 0 3 3 3 2 AAA domain AAA_15 PF13175.1 EIE78643.1 - 2e-07 30.4 0.0 0.11 11.5 0.0 3.6 2 2 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 EIE78643.1 - 4e-07 30.2 0.4 0.0048 17.0 0.1 3.8 2 1 0 2 2 2 2 AAA domain Chromo PF00385.19 EIE78643.1 - 8.1e-07 28.6 0.5 2e-06 27.3 0.3 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF258 PF03193.11 EIE78643.1 - 3.2e-06 26.4 0.1 0.02 14.0 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 EIE78643.1 - 3.3e-06 27.9 0.4 0.029 15.2 0.0 3.6 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.18 EIE78643.1 - 1.1e-05 25.3 0.0 0.15 12.0 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 EIE78643.1 - 1.3e-05 25.6 0.9 0.16 12.4 0.0 3.4 3 1 0 3 3 3 2 Miro-like protein SbcCD_C PF13558.1 EIE78643.1 - 1.9e-05 24.5 0.1 0.035 14.0 0.0 3.1 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.1 EIE78643.1 - 0.00012 22.0 0.1 0.076 12.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 EIE78643.1 - 0.00014 21.7 0.0 0.029 14.1 0.0 3.3 3 0 0 3 3 3 1 Dynamin family AAA_10 PF12846.2 EIE78643.1 - 0.00017 21.1 0.4 1.1 8.6 0.1 3.4 4 0 0 4 4 4 2 AAA-like domain Zeta_toxin PF06414.7 EIE78643.1 - 0.00025 20.2 0.1 0.88 8.6 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin AAA_18 PF13238.1 EIE78643.1 - 0.00026 21.3 2.7 0.59 10.4 0.0 4.0 4 0 0 4 4 3 1 AAA domain ArgK PF03308.11 EIE78643.1 - 0.00078 18.3 0.2 0.58 8.8 0.0 2.5 2 0 0 2 2 2 2 ArgK protein RNA_helicase PF00910.17 EIE78643.1 - 0.00091 19.3 0.3 3.2 7.9 0.0 3.4 3 0 0 3 3 2 1 RNA helicase AAA_23 PF13476.1 EIE78643.1 - 0.00092 19.5 14.2 0.018 15.3 0.0 3.6 2 1 0 2 2 2 1 AAA domain NACHT PF05729.7 EIE78643.1 - 0.001 18.7 0.2 0.23 11.0 0.0 2.6 2 0 0 2 2 2 1 NACHT domain MobB PF03205.9 EIE78643.1 - 0.0015 18.2 0.4 0.49 10.0 0.1 3.3 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 EIE78643.1 - 0.0017 18.0 0.8 1.3 8.5 0.1 3.3 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 EIE78643.1 - 0.0017 18.4 0.0 1.2 9.1 0.0 3.3 3 0 0 3 3 3 1 AAA ATPase domain HEAT_2 PF13646.1 EIE78643.1 - 0.0026 18.0 0.1 0.029 14.6 0.0 2.7 1 1 2 3 3 3 2 HEAT repeats DUF815 PF05673.8 EIE78643.1 - 0.0033 16.3 0.0 2.6 6.9 0.0 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF815) CLASP_N PF12348.3 EIE78643.1 - 0.0054 16.1 0.0 0.25 10.6 0.0 2.6 1 1 0 1 1 1 1 CLASP N terminal AAA_25 PF13481.1 EIE78643.1 - 0.014 14.7 0.0 5.3 6.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 EIE78643.1 - 0.02 15.1 0.8 7.4 6.7 0.0 3.5 4 0 0 4 4 2 0 ATPase family associated with various cellular activities (AAA) Vac14_Fab1_bd PF12755.2 EIE78643.1 - 0.02 15.2 0.1 8.8 6.7 0.0 3.7 4 0 0 4 4 3 0 Vacuolar 14 Fab1-binding region PduV-EutP PF10662.4 EIE78643.1 - 0.026 13.9 0.6 6.6 6.2 0.0 2.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation HEAT_EZ PF13513.1 EIE78643.1 - 0.2 12.2 2.5 3.6 8.2 0.0 4.0 3 1 1 4 4 4 0 HEAT-like repeat DUF87 PF01935.12 EIE78643.1 - 0.36 10.6 9.3 1.3 8.7 0.2 3.9 4 1 0 4 4 4 0 Domain of unknown function DUF87 SAICAR_synt PF01259.13 EIE78644.1 - 6.2e-92 307.1 0.1 7.5e-92 306.9 0.1 1.0 1 0 0 1 1 1 1 SAICAR synthetase BRICHOS PF04089.9 EIE78646.1 - 0.062 13.1 0.0 0.073 12.9 0.0 1.2 1 0 0 1 1 1 0 BRICHOS domain Macoilin PF09726.4 EIE78648.1 - 3.4 5.8 20.8 4.5 5.4 14.4 1.1 1 0 0 1 1 1 0 Transmembrane protein Dicty_REP PF05086.7 EIE78648.1 - 5.1 4.7 27.6 8.4 4.0 19.1 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Polysacc_deac_1 PF01522.16 EIE78649.1 - 4.2e-37 126.5 0.0 7.3e-37 125.7 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 EIE78649.1 - 3.3e-05 22.9 0.1 5.2e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 TBX PF12598.3 EIE78649.1 - 1.2 9.5 10.9 4.7 7.6 4.9 2.6 2 0 0 2 2 2 0 T-box transcription factor TRAM_LAG1_CLN8 PF03798.11 EIE78650.1 - 8.8e-37 126.5 23.1 8.8e-37 126.5 16.0 1.8 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 EIE78650.1 - 5.6e-15 54.5 0.9 1.5e-14 53.1 0.6 1.8 1 0 0 1 1 1 1 TRAM1-like protein GCS PF03074.11 EIE78651.1 - 3.7e-164 546.1 3.2 4.7e-164 545.8 2.2 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase GCS2 PF04107.8 EIE78651.1 - 0.0032 16.6 0.0 0.0058 15.7 0.0 1.3 1 0 0 1 1 1 1 Glutamate-cysteine ligase family 2(GCS2) THP2 PF09432.5 EIE78651.1 - 0.043 13.6 0.0 0.14 11.9 0.0 1.9 1 0 0 1 1 1 0 Tho complex subunit THP2 EF-hand_7 PF13499.1 EIE78652.1 - 1.6e-06 28.1 0.4 2.8e-06 27.3 0.1 1.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EIE78652.1 - 4.3e-05 22.5 0.2 0.00018 20.5 0.0 2.1 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 EIE78652.1 - 0.00083 19.0 0.1 0.0026 17.5 0.0 1.9 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.1 EIE78652.1 - 0.0014 18.2 0.0 0.0025 17.3 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 EIE78652.1 - 0.0039 16.4 0.1 0.0093 15.2 0.0 1.7 2 0 0 2 2 2 1 EF hand DUF3799 PF12684.2 EIE78652.1 - 0.16 11.3 1.4 0.17 11.1 0.9 1.1 1 0 0 1 1 1 0 PDDEXK-like domain of unknown function (DUF3799) Pkinase PF00069.20 EIE78653.1 - 6.9e-54 182.7 0.1 1.2e-53 181.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE78653.1 - 1.1e-22 80.4 0.0 1.7e-22 79.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE78653.1 - 5.3e-07 28.8 0.0 8.5e-07 28.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like PAS_9 PF13426.1 EIE78653.1 - 1.7e-05 25.0 0.0 0.54 10.6 0.0 3.6 3 1 0 3 3 3 2 PAS domain APH PF01636.18 EIE78653.1 - 0.00019 21.2 0.1 0.001 18.8 0.1 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EIE78653.1 - 0.0074 15.3 0.0 0.012 14.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PAS_8 PF13188.1 EIE78653.1 - 0.01 15.6 0.0 7.1 6.6 0.0 3.4 3 0 0 3 3 3 0 PAS domain Suc_Fer-like PF06999.7 EIE78653.1 - 0.088 12.8 0.0 0.26 11.2 0.0 1.7 2 0 0 2 2 2 0 Sucrase/ferredoxin-like Pou PF00157.12 EIE78654.1 - 0.061 12.9 0.1 0.081 12.5 0.0 1.3 1 1 0 1 1 1 0 Pou domain - N-terminal to homeobox domain Antimicrobial18 PF08130.6 EIE78654.1 - 0.094 12.6 1.1 0.15 12.0 0.8 1.3 1 0 0 1 1 1 0 Type A lantibiotic family AA_kinase PF00696.23 EIE78655.1 - 8.7e-42 143.3 0.0 1e-41 143.1 0.0 1.0 1 0 0 1 1 1 1 Amino acid kinase family Lipase_GDSL_2 PF13472.1 EIE78655.1 - 0.034 14.2 0.0 0.12 12.4 0.0 1.9 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family RRN3 PF05327.6 EIE78658.1 - 7.5e-120 400.6 13.5 7.5e-120 400.6 9.4 1.9 1 1 1 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 SapB_2 PF03489.12 EIE78658.1 - 0.081 12.9 0.5 53 3.9 0.0 3.7 3 0 0 3 3 3 0 Saposin-like type B, region 2 DUF2796 PF10986.3 EIE78658.1 - 0.93 9.4 7.5 0.53 10.2 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2796) Sigma70_ner PF04546.8 EIE78658.1 - 1.4 8.4 16.9 4.6 6.8 4.5 2.5 2 0 0 2 2 2 0 Sigma-70, non-essential region CDC45 PF02724.9 EIE78658.1 - 2.5 6.0 15.6 0.64 7.9 1.6 2.2 2 0 0 2 2 2 0 CDC45-like protein NOA36 PF06524.7 EIE78658.1 - 4.3 6.4 18.9 2.9 7.0 1.9 2.4 2 0 0 2 2 2 0 NOA36 protein GalP_UDP_transf PF01087.17 EIE78660.1 - 3.5e-71 239.0 2.7 1.9e-70 236.6 0.8 2.5 3 0 0 3 3 3 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.12 EIE78660.1 - 3.9e-57 192.4 0.0 1.9e-56 190.1 0.0 1.9 1 1 1 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.18 EIE78660.1 - 0.00066 20.1 0.1 0.052 14.0 0.0 2.3 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.3 EIE78660.1 - 0.0019 18.4 0.1 0.0044 17.2 0.0 1.6 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DUF2578 PF10843.3 EIE78660.1 - 0.01 15.5 0.3 0.023 14.3 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2578) Fungal_trans PF04082.13 EIE78661.1 - 1.4e-14 53.6 0.1 2.6e-14 52.7 0.1 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain MgtE_N PF03448.12 EIE78662.1 - 0.045 14.0 2.0 0.25 11.6 0.2 2.5 1 1 2 3 3 3 0 MgtE intracellular N domain Methyltransf_16 PF10294.4 EIE78663.1 - 2.4e-31 108.5 0.1 3e-31 108.2 0.1 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.1 EIE78663.1 - 0.033 13.7 0.1 0.089 12.3 0.1 1.7 1 1 0 1 1 1 0 Methyltransferase domain Lipase_GDSL PF00657.17 EIE78664.1 - 6.1e-08 32.7 0.0 9.5e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EIE78664.1 - 7.8e-08 32.6 0.0 1.2e-07 32.0 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Myb_Cef PF11831.3 EIE78665.1 - 3.3e-37 127.9 4.3 3.3e-37 127.9 3.0 3.0 3 0 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.26 EIE78665.1 - 4.5e-22 77.8 4.6 2.7e-11 43.3 0.3 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EIE78665.1 - 8.5e-21 73.8 7.6 1.1e-13 51.0 2.4 3.0 2 1 1 3 3 3 2 Myb-like DNA-binding domain ORMDL PF04061.9 EIE78666.1 - 1.6e-36 124.8 0.4 1.8e-36 124.6 0.3 1.0 1 0 0 1 1 1 1 ORMDL family GrpE PF01025.14 EIE78667.1 - 0.0031 17.0 1.5 0.0038 16.7 1.0 1.0 1 0 0 1 1 1 1 GrpE Lipoprotein_6 PF01441.14 EIE78667.1 - 0.0046 16.8 1.3 0.0053 16.6 0.9 1.1 1 0 0 1 1 1 1 Lipoprotein GreA_GreB_N PF03449.10 EIE78667.1 - 0.026 14.5 0.7 0.041 13.9 0.5 1.3 1 0 0 1 1 1 0 Transcription elongation factor, N-terminal Apolipoprotein PF01442.13 EIE78667.1 - 0.033 13.7 1.2 0.039 13.4 0.9 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF1045 PF06299.7 EIE78667.1 - 0.096 12.3 0.7 0.12 12.0 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1045) IFP_35_N PF07334.8 EIE78667.1 - 0.14 12.1 0.3 0.17 11.8 0.2 1.1 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus P4Ha_N PF08336.6 EIE78667.1 - 0.16 11.8 0.8 0.19 11.5 0.6 1.0 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region MFS_1 PF07690.11 EIE78668.1 - 1.5e-20 73.2 28.3 2.8e-20 72.3 19.6 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily SpoIIIAC PF06686.6 EIE78668.1 - 1.3 8.8 9.0 2.5 7.9 0.1 3.1 3 0 0 3 3 3 0 Stage III sporulation protein AC/AD protein family Pex24p PF06398.6 EIE78668.1 - 2.8 6.6 9.9 0.32 9.7 3.0 2.0 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin Adeno_E3_14_5 PF04834.7 EIE78668.1 - 6 7.3 7.2 0.84 10.0 0.1 3.0 3 1 1 4 4 4 0 Early E3 14.5 kDa protein AMP-binding PF00501.23 EIE78669.1 - 2e-50 171.4 0.0 2.8e-50 170.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme PPR PF01535.15 EIE78670.1 - 1.3e-08 34.2 0.0 0.0019 18.0 0.0 3.8 4 0 0 4 4 4 2 PPR repeat PPR_3 PF13812.1 EIE78670.1 - 2.1e-07 30.6 0.2 0.00014 21.8 0.0 4.1 4 0 0 4 4 4 1 Pentatricopeptide repeat domain PPR_2 PF13041.1 EIE78670.1 - 6.3e-07 29.2 0.3 7.7e-05 22.5 0.0 3.5 3 2 2 5 5 5 2 PPR repeat family TPR_19 PF14559.1 EIE78670.1 - 0.00028 21.1 1.8 0.62 10.4 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat PPR_1 PF12854.2 EIE78670.1 - 0.0062 15.9 0.0 0.017 14.5 0.0 1.8 2 0 0 2 2 2 1 PPR repeat TPR_1 PF00515.23 EIE78670.1 - 0.069 12.7 0.1 0.58 9.8 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 EIE78670.1 - 0.077 12.9 8.3 8.2 6.4 0.2 4.1 4 1 0 4 4 4 0 Tetratricopeptide repeat Aminotran_5 PF00266.14 EIE78671.1 - 1.7e-45 155.3 0.0 2.3e-45 154.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Myc_N PF01056.13 EIE78672.1 - 0.021 14.0 0.2 0.03 13.4 0.1 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Pantoate_ligase PF02569.10 EIE78674.1 - 1.3e-40 138.9 0.0 1.5e-40 138.6 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase USP7_ICP0_bdg PF12436.3 EIE78675.1 - 1.5e-63 214.3 0.1 9.3e-62 208.4 0.1 2.8 3 0 0 3 3 3 1 ICP0-binding domain of Ubiquitin-specific protease 7 UCH PF00443.24 EIE78675.1 - 2.5e-58 197.3 1.3 4.3e-58 196.5 0.9 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.1 EIE78675.1 - 7.7e-52 175.8 6.4 1.6e-50 171.5 0.2 4.0 4 0 0 4 4 4 1 Ubiquitin-specific protease C-terminal UCH_1 PF13423.1 EIE78675.1 - 2.7e-31 109.0 0.0 4.7e-31 108.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Mpp10 PF04006.7 EIE78677.1 - 1.1e-121 407.1 80.9 1.6e-121 406.6 56.1 1.1 1 0 0 1 1 1 1 Mpp10 protein DUF4055 PF13264.1 EIE78677.1 - 0.27 11.3 4.1 0.94 9.5 2.9 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4055) Fumarate_red_C PF02300.12 EIE78678.1 - 0.12 12.2 0.0 0.16 11.8 0.0 1.1 1 0 0 1 1 1 0 Fumarate reductase subunit C HTH_29 PF13551.1 EIE78679.1 - 6.3e-06 26.3 0.0 2.3e-05 24.5 0.0 2.0 1 1 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.1 EIE78679.1 - 3.4e-05 24.5 0.0 0.00018 22.2 0.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain DDE_3 PF13358.1 EIE78679.1 - 9.8e-05 22.1 0.6 0.00085 19.0 0.0 2.6 3 0 0 3 3 3 1 DDE superfamily endonuclease HTH_28 PF13518.1 EIE78679.1 - 0.00054 19.8 0.0 0.0011 18.8 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain YjcZ PF13990.1 EIE78679.1 - 0.0092 15.1 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 YjcZ-like protein HTH_WhiA PF02650.9 EIE78679.1 - 0.032 14.6 0.0 0.096 13.0 0.0 1.8 1 0 0 1 1 1 0 WhiA C-terminal HTH domain DUF445 PF04286.7 EIE78679.1 - 0.19 11.2 3.8 0.3 10.5 2.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF445) She9_MDM33 PF05546.6 EIE78681.1 - 1.3e-65 220.9 20.4 1.3e-65 220.8 9.9 2.8 2 0 0 2 2 2 1 She9 / Mdm33 family UBN_AB PF14075.1 EIE78681.1 - 1.3e-13 51.1 3.2 1.3e-13 51.1 2.2 4.3 3 2 0 3 3 3 1 Ubinuclein conserved middle domain HUN PF08729.5 EIE78681.1 - 5.2e-10 39.0 6.1 1.8e-09 37.2 4.2 2.0 1 0 0 1 1 1 1 HPC2 and ubinuclein domain LPP PF04728.8 EIE78681.1 - 0.42 10.4 0.0 0.42 10.4 0.0 3.3 2 1 1 3 3 3 0 Lipoprotein leucine-zipper BRCT PF00533.21 EIE78682.1 - 7e-11 42.1 0.0 1.6e-10 40.9 0.0 1.6 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EIE78682.1 - 7.8e-11 41.6 0.0 1.3e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 twin BRCT domain fn3 PF00041.16 EIE78682.1 - 4.3e-05 23.5 0.0 0.00041 20.4 0.0 2.2 2 0 0 2 2 2 1 Fibronectin type III domain DUF1241 PF06840.6 EIE78682.1 - 0.1 11.8 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1241) SAP18 PF06487.7 EIE78683.1 - 1.1e-28 99.4 0.1 9.3e-21 73.8 0.0 2.7 2 1 1 3 3 3 2 Sin3 associated polypeptide p18 (SAP18) Zip PF02535.17 EIE78684.1 - 4.8e-28 98.0 9.8 4.8e-28 98.0 6.8 2.2 1 1 1 2 2 2 1 ZIP Zinc transporter Claudin_2 PF13903.1 EIE78684.1 - 0.00033 20.3 0.1 0.0082 15.8 0.0 2.6 2 1 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction COPIIcoated_ERV PF07970.7 EIE78685.1 - 2.2e-16 60.1 0.6 2.7e-16 59.8 0.4 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EIE78685.1 - 7.4e-08 32.2 0.0 1.2e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Lipase_3 PF01764.20 EIE78688.1 - 3.5e-14 52.6 0.0 6.1e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Amidase PF01425.16 EIE78689.1 - 2.2e-79 267.3 0.0 2.7e-79 267.1 0.0 1.0 1 0 0 1 1 1 1 Amidase NAD_synthase PF02540.12 EIE78689.1 - 0.0049 15.8 0.3 0.011 14.6 0.2 1.5 1 0 0 1 1 1 1 NAD synthase RhoGAP PF00620.22 EIE78690.1 - 5.8e-52 175.3 0.3 1.5e-51 173.9 0.1 1.8 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.17 EIE78690.1 - 6.3e-16 58.1 31.3 3.7e-09 36.5 3.5 3.5 3 0 0 3 3 3 2 LIM domain C1_1 PF00130.17 EIE78690.1 - 2.9e-08 33.3 12.2 2.9e-08 33.3 8.5 4.0 2 1 3 5 5 5 1 Phorbol esters/diacylglycerol binding domain (C1 domain) bZIP_1 PF00170.16 EIE78690.1 - 0.19 11.6 8.7 2.9 7.9 1.0 3.2 2 0 0 2 2 2 0 bZIP transcription factor Cep57_CLD_2 PF14197.1 EIE78690.1 - 3.4 7.6 14.0 3.8 7.5 4.0 3.2 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 CENP-F_leu_zip PF10473.4 EIE78690.1 - 3.9 7.3 21.4 0.028 14.2 0.9 2.9 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1754 PF08555.5 EIE78691.1 - 0.00023 21.7 32.6 0.031 14.8 19.0 2.8 2 1 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) Atrophin-1 PF03154.10 EIE78691.1 - 0.14 10.2 12.8 0.15 10.2 8.8 1.0 1 0 0 1 1 1 0 Atrophin-1 family DUF2524 PF10732.4 EIE78691.1 - 0.48 10.5 3.7 0.67 10.1 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2524) Phage_min_cap2 PF06152.6 EIE78691.1 - 0.51 9.2 4.8 0.58 9.0 3.3 1.3 1 0 0 1 1 1 0 Phage minor capsid protein 2 DEPP PF15343.1 EIE78691.1 - 0.6 9.6 6.9 0.71 9.4 4.8 1.1 1 0 0 1 1 1 0 Decidual protein induced by progesterone family HemY_N PF07219.8 EIE78691.1 - 0.74 9.3 5.9 0.39 10.2 0.9 2.0 1 1 1 2 2 2 0 HemY protein N-terminus DUF724 PF05266.9 EIE78691.1 - 0.87 9.1 13.1 1.2 8.7 9.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) ATP11 PF06644.6 EIE78691.1 - 0.98 8.8 8.5 1.1 8.6 5.9 1.0 1 0 0 1 1 1 0 ATP11 protein PA26 PF04636.8 EIE78691.1 - 1.5 7.4 6.0 1.7 7.2 4.1 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Ax_dynein_light PF10211.4 EIE78691.1 - 1.8 8.3 11.7 2.3 8.0 8.1 1.2 1 0 0 1 1 1 0 Axonemal dynein light chain Dsh_C PF12316.3 EIE78691.1 - 4.3 7.3 6.9 5 7.1 4.8 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal HSP70 PF00012.15 EIE78691.1 - 7.7 4.2 8.7 8.4 4.1 6.0 1.0 1 0 0 1 1 1 0 Hsp70 protein PRP1_N PF06424.7 EIE78691.1 - 9.1 6.6 12.8 18 5.6 8.9 1.5 1 1 0 1 1 1 0 PRP1 splicing factor, N-terminal Elong_Iki1 PF10483.4 EIE78692.1 - 9.9e-16 57.9 0.3 1.2e-15 57.6 0.2 1.2 1 0 0 1 1 1 1 Elongator subunit Iki1 RabGAP-TBC PF00566.13 EIE78693.1 - 2.6e-56 190.5 1.7 4.4e-56 189.7 1.2 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RNA_capsid PF03035.9 EIE78693.1 - 0.15 11.8 2.1 0.12 12.1 0.3 1.6 2 0 0 2 2 2 0 Calicivirus putative RNA polymerase/capsid protein ADH_zinc_N PF00107.21 EIE78694.1 - 3.2e-19 68.7 0.1 6.5e-19 67.7 0.0 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIE78694.1 - 7.4e-08 33.3 0.0 2.5e-07 31.6 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIE78694.1 - 0.00011 21.8 0.0 0.00026 20.7 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ACP_syn_III_C PF08541.5 EIE78694.1 - 0.045 13.7 0.0 0.15 12.1 0.0 1.9 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal NAD_binding_10 PF13460.1 EIE78694.1 - 0.094 12.7 0.1 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding NAD_binding_7 PF13241.1 EIE78694.1 - 0.11 12.7 1.3 0.11 12.7 0.1 1.6 2 0 0 2 2 2 0 Putative NAD(P)-binding MAPEG PF01124.13 EIE78695.1 - 7.3e-24 83.8 0.1 8.7e-24 83.5 0.1 1.0 1 0 0 1 1 1 1 MAPEG family Pkinase PF00069.20 EIE78696.1 - 1.1e-41 142.6 0.0 1.8e-39 135.4 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIE78696.1 - 5.1e-21 74.9 0.0 1.1e-20 73.8 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EIE78696.1 - 6e-08 33.0 0.6 1.2e-07 32.1 0.4 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Kdo PF06293.9 EIE78696.1 - 0.00075 18.6 0.0 0.0013 17.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PX PF00787.19 EIE78696.1 - 0.0024 17.6 0.9 0.0054 16.5 0.6 1.6 1 0 0 1 1 1 1 PX domain Kinase-like PF14531.1 EIE78696.1 - 0.016 14.1 0.0 0.026 13.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 EIE78696.1 - 0.088 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family adh_short PF00106.20 EIE78697.1 - 6.7e-24 84.6 0.0 9.4e-24 84.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIE78697.1 - 2.2e-09 37.4 0.0 2.9e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIE78697.1 - 5.4e-07 29.4 0.0 8.3e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EIE78697.1 - 0.00082 19.4 0.0 0.0022 18.0 0.0 1.6 2 0 0 2 2 2 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EIE78697.1 - 0.0043 16.0 0.4 0.0066 15.3 0.2 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Tox-WTIP PF15654.1 EIE78697.1 - 0.091 12.3 0.0 0.24 11.0 0.0 1.7 1 0 0 1 1 1 0 Toxin with a conserved tryptophan and TIP tripeptide motif cobW PF02492.14 EIE78698.1 - 1.7e-34 118.8 0.0 2.1e-34 118.5 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 EIE78698.1 - 8.8e-05 21.4 0.1 0.29 9.8 0.0 2.1 2 0 0 2 2 2 2 ArgK protein MMR_HSR1 PF01926.18 EIE78698.1 - 0.00013 21.9 0.1 0.00071 19.5 0.0 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_18 PF13238.1 EIE78698.1 - 0.014 15.7 0.0 0.024 14.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EIE78698.1 - 0.017 15.9 0.1 0.033 14.9 0.1 1.5 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EIE78698.1 - 0.018 14.7 0.0 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase AAA_5 PF07728.9 EIE78698.1 - 0.023 14.4 0.0 0.065 12.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) CbiA PF01656.18 EIE78698.1 - 0.048 13.0 0.1 0.069 12.5 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ABC_tran PF00005.22 EIE78698.1 - 0.062 13.5 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 ABC transporter IstB_IS21 PF01695.12 EIE78698.1 - 0.074 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.8 EIE78698.1 - 0.075 11.7 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 TIP49 C-terminus AAA_22 PF13401.1 EIE78698.1 - 0.11 12.6 0.0 0.4 10.8 0.0 1.9 2 1 1 3 3 3 0 AAA domain ResIII PF04851.10 EIE78698.1 - 0.14 12.0 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Pox_A32 PF04665.7 EIE78698.1 - 0.14 11.4 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein ALAD PF00490.16 EIE78699.1 - 3.6e-119 397.4 0.0 4e-119 397.2 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Exo_endo_phos PF03372.18 EIE78700.1 - 5.1e-13 49.5 0.4 7e-13 49.0 0.3 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SPT6_acidic PF14632.1 EIE78700.1 - 0.066 13.3 1.0 0.11 12.6 0.7 1.3 1 0 0 1 1 1 0 Acidic N-terminal SPT6 tRNA-synt_1b PF00579.20 EIE78701.1 - 2.3e-58 197.6 0.0 2.8e-58 197.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) WD40 PF00400.27 EIE78702.1 - 5.8e-36 121.0 11.0 1.8e-08 33.9 0.1 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 EIE78702.1 - 2.9e-11 42.2 7.3 0.00026 19.2 0.1 3.2 2 1 1 3 3 3 3 Nucleoporin Nup120/160 F-box-like PF12937.2 EIE78702.1 - 1.1e-09 37.7 0.2 2.3e-09 36.8 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIE78702.1 - 1.2e-09 37.5 1.0 2.5e-09 36.5 0.7 1.6 1 0 0 1 1 1 1 F-box domain CDtoxinA PF03498.9 EIE78702.1 - 0.0002 20.7 0.4 0.21 10.9 0.0 2.8 3 0 0 3 3 3 2 Cytolethal distending toxin A/C family PQQ_2 PF13360.1 EIE78702.1 - 0.005 16.3 0.4 1.6 8.1 0.1 2.3 2 0 0 2 2 2 2 PQQ-like domain Thiolase_N PF00108.18 EIE78703.1 - 6.1e-82 274.5 2.8 1.9e-81 272.9 0.7 2.0 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EIE78703.1 - 1.6e-47 159.9 0.1 3.1e-47 159.0 0.1 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain Guanylate_kin PF00625.16 EIE78704.1 - 2.2e-65 219.5 0.0 2.4e-65 219.4 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_18 PF13238.1 EIE78704.1 - 2.6e-06 27.7 0.0 8.5e-06 26.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EIE78704.1 - 5.2e-06 26.3 0.0 2.3e-05 24.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EIE78704.1 - 6.6e-06 26.3 0.0 1.4e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EIE78704.1 - 3.4e-05 24.6 0.1 6.3e-05 23.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EIE78704.1 - 5.9e-05 23.3 0.0 6.8e-05 23.1 0.0 1.4 1 1 0 1 1 1 1 ABC transporter AAA_16 PF13191.1 EIE78704.1 - 6.6e-05 22.9 0.0 0.00018 21.5 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 EIE78704.1 - 0.00023 20.3 0.0 0.0003 20.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_14 PF13173.1 EIE78704.1 - 0.00035 20.4 0.0 0.00057 19.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EIE78704.1 - 0.00036 20.0 0.3 0.00066 19.1 0.2 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_10 PF12846.2 EIE78704.1 - 0.00041 19.8 0.3 0.00041 19.8 0.2 1.4 1 1 0 1 1 1 1 AAA-like domain AAA_23 PF13476.1 EIE78704.1 - 0.00098 19.4 0.8 0.0014 18.9 0.3 1.5 1 1 0 1 1 1 1 AAA domain Miro PF08477.8 EIE78704.1 - 0.0016 18.9 0.1 0.0023 18.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein cobW PF02492.14 EIE78704.1 - 0.0016 17.9 0.3 0.03 13.7 0.0 2.3 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain T2SE PF00437.15 EIE78704.1 - 0.0018 17.2 0.1 0.0027 16.6 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.1 EIE78704.1 - 0.0044 16.7 0.0 0.012 15.3 0.0 1.8 2 0 0 2 2 1 1 Part of AAA domain Arch_ATPase PF01637.13 EIE78704.1 - 0.005 16.5 0.1 0.005 16.5 0.1 1.4 1 1 0 1 1 1 1 Archaeal ATPase NACHT PF05729.7 EIE78704.1 - 0.0054 16.4 0.0 0.0089 15.7 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_28 PF13521.1 EIE78704.1 - 0.0057 16.6 0.0 0.024 14.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.10 EIE78704.1 - 0.0074 15.0 0.0 0.0092 14.7 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein NTPase_1 PF03266.10 EIE78704.1 - 0.0091 15.7 0.1 0.016 14.9 0.0 1.5 1 1 0 1 1 1 1 NTPase RNA_helicase PF00910.17 EIE78704.1 - 0.0097 16.0 0.1 0.017 15.2 0.1 1.7 1 1 0 1 1 1 1 RNA helicase DUF2075 PF09848.4 EIE78704.1 - 0.0098 14.8 0.0 0.017 14.1 0.0 1.7 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) KAP_NTPase PF07693.9 EIE78704.1 - 0.014 14.4 0.0 0.014 14.4 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain MMR_HSR1 PF01926.18 EIE78704.1 - 0.018 15.0 0.0 0.028 14.3 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_24 PF13479.1 EIE78704.1 - 0.021 14.4 0.0 0.03 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.12 EIE78704.1 - 0.024 14.0 0.1 2.1 7.7 0.0 2.2 1 1 1 2 2 2 0 Thymidylate kinase MobB PF03205.9 EIE78704.1 - 0.026 14.2 0.0 0.054 13.1 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Viral_helicase1 PF01443.13 EIE78704.1 - 0.03 13.8 0.0 0.043 13.3 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_21 PF13304.1 EIE78704.1 - 0.034 14.0 0.0 0.046 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EIE78704.1 - 0.059 13.5 0.1 0.12 12.5 0.1 1.6 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 EIE78704.1 - 0.061 12.9 0.0 0.18 11.4 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 ADK PF00406.17 EIE78704.1 - 0.069 13.0 0.5 40 4.0 0.0 3.0 2 1 1 3 3 3 0 Adenylate kinase Adeno_IVa2 PF02456.10 EIE78704.1 - 0.084 11.5 0.0 0.14 10.7 0.0 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein NB-ARC PF00931.17 EIE78704.1 - 0.091 11.5 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_30 PF13604.1 EIE78704.1 - 0.11 12.1 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EIE78704.1 - 0.11 11.5 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Pox_A32 PF04665.7 EIE78704.1 - 0.13 11.4 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_25 PF13481.1 EIE78704.1 - 0.14 11.5 0.3 0.45 9.8 0.0 1.9 2 1 0 2 2 2 0 AAA domain Cyto_heme_lyase PF01265.12 EIE78706.1 - 6.3e-57 193.1 12.4 6e-52 176.7 8.5 2.9 1 1 1 2 2 2 2 Cytochrome c/c1 heme lyase DUF4597 PF15366.1 EIE78707.1 - 0.091 12.3 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4597) Met_10 PF02475.11 EIE78708.1 - 6.9e-31 107.4 0.0 3.4e-30 105.1 0.0 1.9 1 1 1 2 2 2 1 Met-10+ like-protein Methyltransf_26 PF13659.1 EIE78708.1 - 2.2e-06 27.7 0.0 2.7e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIE78708.1 - 1e-05 26.1 0.0 1.4e-05 25.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 EIE78708.1 - 0.0003 20.3 0.0 0.0063 16.0 0.0 2.2 1 1 1 2 2 2 1 RNA cap guanine-N2 methyltransferase MethyltransfD12 PF02086.10 EIE78708.1 - 0.00052 19.5 0.0 0.00076 19.0 0.0 1.3 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase MTS PF05175.9 EIE78708.1 - 0.0011 18.3 0.0 0.0022 17.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 EIE78708.1 - 0.0029 16.7 0.0 0.0039 16.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TRM PF02005.11 EIE78708.1 - 0.0083 15.0 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase tRNA_U5-meth_tr PF05958.6 EIE78708.1 - 0.055 12.1 0.0 0.08 11.6 0.0 1.3 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Phage_DNA_bind PF02303.12 EIE78709.1 - 0.0055 16.6 0.3 0.011 15.6 0.2 1.5 1 0 0 1 1 1 1 Helix-destabilising protein Bromo_MP PF01573.11 EIE78709.1 - 0.14 11.0 1.5 0.21 10.5 1.0 1.1 1 0 0 1 1 1 0 Bromovirus movement protein DUF3414 PF11894.3 EIE78710.1 - 5e-180 600.5 30.2 7.5e-179 596.6 21.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3414) IF4E PF01652.13 EIE78710.1 - 4e-56 189.0 1.7 7.5e-56 188.1 1.2 1.5 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Noc2 PF03715.8 EIE78711.1 - 1.5e-57 194.7 0.4 1.5e-57 194.7 0.3 2.0 2 0 0 2 2 2 1 Noc2p family EST1 PF10374.4 EIE78711.1 - 0.17 11.9 4.8 0.29 11.1 0.0 3.4 2 2 0 2 2 2 0 Telomerase activating protein Est1 SAPS PF04499.10 EIE78711.1 - 4.8 5.7 17.3 8.2 4.9 12.0 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Zip PF02535.17 EIE78711.1 - 6.5 5.6 6.2 11 4.9 4.3 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter TFIIA PF03153.8 EIE78711.1 - 9.7 5.9 29.8 15 5.3 20.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nic96 PF04097.9 EIE78712.1 - 7.7e-96 321.5 26.0 1.5e-64 218.2 7.4 2.2 1 1 1 2 2 2 2 Nup93/Nic96 TMCO5 PF14992.1 EIE78713.1 - 0.038 13.1 0.1 0.041 13.0 0.1 1.1 1 0 0 1 1 1 0 TMCO5 family Tmemb_cc2 PF10267.4 EIE78713.1 - 0.065 11.8 0.4 0.16 10.5 0.3 1.4 1 1 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DDE_3 PF13358.1 EIE78714.1 - 2.1e-18 66.5 0.0 2.6e-18 66.1 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Methyltransf_26 PF13659.1 EIE78715.1 - 8.1e-08 32.3 0.0 1.3e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIE78715.1 - 1.1e-07 31.5 0.1 1.8e-07 30.8 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIE78715.1 - 1.1e-06 29.2 0.0 1.9e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIE78715.1 - 1.5e-05 25.2 0.1 6.4e-05 23.2 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Met_10 PF02475.11 EIE78715.1 - 5e-05 22.9 0.1 9.4e-05 22.0 0.1 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_11 PF08241.7 EIE78715.1 - 0.00044 20.6 0.0 0.0011 19.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 EIE78715.1 - 0.00048 19.5 0.3 0.0054 16.0 0.2 2.1 1 1 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_12 PF08242.7 EIE78715.1 - 0.0073 16.7 0.0 0.015 15.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 EIE78715.1 - 0.051 13.1 0.0 0.085 12.4 0.0 1.5 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Xan_ur_permease PF00860.15 EIE78716.1 - 6.2e-59 199.4 34.8 1.9e-39 135.2 11.9 2.4 3 0 0 3 3 3 2 Permease family Abhydrolase_6 PF12697.2 EIE78717.1 - 1.3e-23 84.1 0.0 1.6e-23 83.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIE78717.1 - 1.2e-08 34.8 0.0 2.4e-08 33.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIE78717.1 - 2.2e-06 27.4 0.0 2.8e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ndr PF03096.9 EIE78717.1 - 0.002 16.6 0.0 0.0029 16.1 0.0 1.1 1 0 0 1 1 1 1 Ndr family PAF-AH_p_II PF03403.8 EIE78717.1 - 0.0028 15.9 0.1 0.05 11.8 0.0 2.0 2 0 0 2 2 2 1 Platelet-activating factor acetylhydrolase, isoform II DUF915 PF06028.6 EIE78717.1 - 0.077 12.0 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Lipase_3 PF01764.20 EIE78717.1 - 0.08 12.5 0.0 0.24 10.9 0.0 1.7 2 0 0 2 2 2 0 Lipase (class 3) Methyltransf_8 PF05148.10 EIE78718.1 - 2e-81 272.8 4.5 4.6e-81 271.6 0.1 2.2 1 1 0 2 2 2 1 Hypothetical methyltransferase Methyltransf_11 PF08241.7 EIE78718.1 - 4.5e-10 39.8 0.0 2e-09 37.8 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIE78718.1 - 2.6e-05 23.4 0.2 0.00011 21.4 0.1 2.1 2 1 1 3 3 3 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EIE78718.1 - 0.00024 20.5 0.2 0.016 14.6 0.0 2.5 1 1 1 2 2 2 1 Methyltransferase small domain DUF257 PF03192.8 EIE78718.1 - 0.017 14.4 0.0 0.026 13.8 0.0 1.2 1 0 0 1 1 1 0 Pyrococcus protein of unknown function, DUF257 Methyltransf_23 PF13489.1 EIE78718.1 - 0.065 12.9 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Utp14 PF04615.8 EIE78718.1 - 0.11 10.6 38.2 0.19 9.8 26.5 1.3 1 0 0 1 1 1 0 Utp14 protein LMBR1 PF04791.11 EIE78718.1 - 0.13 10.8 6.4 0.15 10.5 4.4 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Methyltransf_12 PF08242.7 EIE78718.1 - 0.49 10.9 0.1 0.49 10.9 0.0 3.7 2 2 0 2 2 2 0 Methyltransferase domain GTSE1_N PF15259.1 EIE78718.1 - 1.1 9.1 27.9 1.1 9.1 6.8 4.2 4 0 0 4 4 4 0 G-2 and S-phase expressed 1 EMG1 PF03587.9 EIE78719.1 - 5.6e-45 153.1 0.0 1.3e-32 112.7 0.0 2.1 1 1 1 2 2 2 2 EMG1/NEP1 methyltransferase NUDIX PF00293.23 EIE78720.1 - 1.4e-08 34.5 0.0 1.6e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_2 PF13869.1 EIE78720.1 - 0.0011 18.3 0.0 0.0012 18.1 0.0 1.1 1 0 0 1 1 1 1 Nucleotide hydrolase Cyclin_N PF00134.18 EIE78721.1 - 0.049 13.1 0.1 0.28 10.7 0.0 2.0 2 0 0 2 2 2 0 Cyclin, N-terminal domain Hist_deacetyl PF00850.14 EIE78722.1 - 1.8e-78 264.0 0.0 2.7e-78 263.4 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain IF-2 PF11987.3 EIE78723.1 - 8e-19 67.5 0.0 1.8e-18 66.4 0.0 1.6 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 EIE78723.1 - 3.4e-15 55.9 1.7 4.4e-10 39.5 0.0 2.5 2 0 0 2 2 2 2 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 EIE78723.1 - 0.0014 18.2 0.1 0.0045 16.5 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 GTP_EFTU PF00009.22 EIE78724.1 - 2.3e-22 79.3 3.2 2.5e-22 79.2 0.0 2.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EIE78724.1 - 6.8e-05 22.8 0.0 0.0002 21.2 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EIE78724.1 - 0.0028 17.8 0.1 0.014 15.5 0.0 2.3 1 1 0 1 1 1 1 AAA domain Miro PF08477.8 EIE78724.1 - 0.059 13.8 0.0 0.059 13.8 0.0 3.3 3 2 0 3 3 3 0 Miro-like protein Cullin PF00888.17 EIE78725.1 - 8.2e-109 364.7 23.7 8.4e-109 364.7 12.4 2.6 2 1 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.4 EIE78725.1 - 1.5e-27 95.1 4.6 4.5e-27 93.6 3.2 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain HTH_IclR PF09339.5 EIE78725.1 - 6.1e-06 25.7 0.2 1.3e-05 24.7 0.1 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_24 PF13412.1 EIE78725.1 - 2.5e-05 23.5 0.2 9.5e-05 21.7 0.0 2.1 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.2 EIE78725.1 - 5.4e-05 22.7 0.0 0.00015 21.3 0.0 1.7 1 0 0 1 1 1 1 MarR family TrmB PF01978.14 EIE78725.1 - 0.00021 20.9 0.1 0.23 11.1 0.0 2.6 2 0 0 2 2 2 2 Sugar-specific transcriptional regulator TrmB MarR PF01047.17 EIE78725.1 - 0.00045 19.8 0.1 0.026 14.2 0.0 2.5 2 0 0 2 2 2 1 MarR family HTH_5 PF01022.15 EIE78725.1 - 0.0047 16.5 0.1 0.014 15.0 0.0 1.8 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family Rrf2 PF02082.15 EIE78725.1 - 0.012 15.6 0.0 0.039 14.0 0.0 1.8 1 0 0 1 1 1 0 Transcriptional regulator HTH_27 PF13463.1 EIE78725.1 - 0.015 15.5 0.0 0.045 14.0 0.0 1.8 1 0 0 1 1 1 0 Winged helix DNA-binding domain WGG PF10273.4 EIE78725.1 - 0.074 13.1 0.6 3.9 7.6 0.1 3.0 2 0 0 2 2 2 0 Pre-rRNA-processing protein TSR2 HTH_20 PF12840.2 EIE78725.1 - 0.1 12.4 0.1 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Pkinase PF00069.20 EIE78728.1 - 2.7e-46 157.8 0.2 9.3e-40 136.4 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIE78728.1 - 2.9e-18 65.8 0.0 9.8e-18 64.1 0.0 1.7 1 1 1 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE78728.1 - 0.0046 15.9 0.0 0.0068 15.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Zn_clus PF00172.13 EIE78729.1 - 1.6e-05 24.7 4.6 3.3e-05 23.6 3.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mob_synth_C PF06463.8 EIE78729.1 - 0.059 13.0 0.8 0.059 13.0 0.6 1.5 2 0 0 2 2 2 0 Molybdenum Cofactor Synthesis C HisG PF01634.13 EIE78730.1 - 2.9e-48 163.5 0.4 4.2e-48 162.9 0.3 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase Mito_carr PF00153.22 EIE78730.1 - 8.5e-30 102.3 1.1 1.1e-13 50.6 0.0 2.7 3 0 0 3 3 3 2 Mitochondrial carrier protein HisG_C PF08029.6 EIE78730.1 - 4.7e-25 87.3 0.1 9.9e-25 86.2 0.1 1.6 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.6 EIE78730.1 - 0.00019 21.1 0.1 0.00032 20.3 0.0 1.3 1 0 0 1 1 1 1 NMT1/THI5 like UreF PF01730.11 EIE78731.1 - 3.3e-13 49.9 0.0 4.7e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 UreF WD40 PF00400.27 EIE78732.1 - 5.3e-60 197.2 24.1 5.3e-11 41.9 0.3 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EIE78732.1 - 4.6e-06 26.4 0.1 3.1e-05 23.7 0.0 2.2 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EIE78732.1 - 4.7e-05 21.7 10.3 0.0038 15.4 0.7 4.8 2 2 2 5 5 5 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 EIE78732.1 - 0.001 17.4 0.1 0.79 7.9 0.0 2.4 2 0 0 2 2 2 2 Cytochrome D1 heme domain Nbas_N PF15492.1 EIE78732.1 - 0.011 14.8 0.1 1.2 8.1 0.0 2.5 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal CCDC50_N PF15295.1 EIE78733.1 - 0.14 12.0 5.9 0.19 11.6 4.1 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 50 N-terminus CCDC66 PF15236.1 EIE78733.1 - 0.24 11.0 8.8 0.29 10.7 6.1 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 66 Cyclin PF08613.6 EIE78734.1 - 4.6e-15 56.3 0.5 7.5e-15 55.6 0.4 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EIE78734.1 - 0.001 18.6 1.1 0.0021 17.6 0.5 1.8 1 1 0 1 1 1 1 Cyclin, N-terminal domain WD40 PF00400.27 EIE78735.1 - 5.8e-05 22.8 0.1 0.049 13.5 0.0 2.7 2 0 0 2 2 2 2 WD domain, G-beta repeat Pectate_lyase22 PF14583.1 EIE78735.1 - 0.0047 15.4 0.0 0.0069 14.8 0.0 1.2 1 0 0 1 1 1 1 Oligogalacturonate lyase DUF1801 PF08818.6 EIE78735.1 - 0.017 15.2 0.1 0.06 13.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DU1801) START PF01852.14 EIE78736.1 - 1.2e-12 47.5 0.8 6.5e-06 25.6 0.0 2.6 2 0 0 2 2 2 2 START domain RBP_receptor PF14752.1 EIE78737.1 - 2.8e-15 55.6 15.2 3.9e-11 42.0 2.8 3.0 3 1 0 3 3 3 2 Retinol binding protein receptor RPN7 PF10602.4 EIE78738.1 - 7.2e-44 149.2 0.2 1.5e-43 148.2 0.1 1.6 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 EIE78738.1 - 1.8e-18 66.7 2.1 2.9e-18 66.0 0.6 2.0 2 0 0 2 2 2 1 PCI domain DDT PF02791.12 EIE78738.1 - 0.01 15.5 0.6 0.084 12.6 0.1 2.5 2 1 1 3 3 3 0 DDT domain PCI_Csn8 PF10075.4 EIE78738.1 - 0.015 15.0 0.7 0.081 12.6 0.2 2.2 2 0 0 2 2 2 0 COP9 signalosome, subunit CSN8 DUF2204 PF09970.4 EIE78738.1 - 0.17 11.3 2.5 0.49 9.8 0.4 2.2 2 0 0 2 2 2 0 Nucleotidyl transferase of unknown function (DUF2204) Methyltransf_11 PF08241.7 EIE78739.1 - 5.6e-12 45.9 0.0 2.6e-11 43.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIE78739.1 - 4.7e-11 42.6 0.0 8.4e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIE78739.1 - 1.5e-09 38.2 0.0 1e-08 35.5 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIE78739.1 - 4.9e-09 35.9 0.0 3.3e-08 33.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIE78739.1 - 4.7e-08 33.3 0.0 1.6e-06 28.3 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIE78739.1 - 3e-05 23.2 0.0 9.6e-05 21.6 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EIE78739.1 - 4.3e-05 24.0 0.0 0.00027 21.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain CheR PF01739.13 EIE78739.1 - 0.00082 18.7 0.0 0.0022 17.3 0.0 1.7 1 1 0 1 1 1 1 CheR methyltransferase, SAM binding domain Methyltransf_4 PF02390.12 EIE78739.1 - 0.0027 16.7 0.0 0.025 13.6 0.0 2.1 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_29 PF03141.11 EIE78739.1 - 0.0046 15.3 0.0 0.0089 14.4 0.0 1.4 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase F-actin_cap_A PF01267.12 EIE78740.1 - 2.1e-70 236.8 1.7 2.4e-70 236.6 1.2 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit DinI PF06183.8 EIE78740.1 - 0.014 15.4 0.1 0.047 13.7 0.0 1.9 2 0 0 2 2 2 0 DinI-like family Rav1p_C PF12234.3 EIE78740.1 - 0.077 11.1 0.0 0.12 10.5 0.0 1.2 1 0 0 1 1 1 0 RAVE protein 1 C terminal YolD PF08863.5 EIE78740.1 - 0.11 12.3 0.2 5 7.0 0.0 2.5 3 0 0 3 3 3 0 YolD-like protein DUF3983 PF13137.1 EIE78741.1 - 0.22 11.2 0.2 0.22 11.2 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3983) Sel1 PF08238.7 EIE78742.1 - 5.7e-24 84.0 8.1 5e-09 36.5 0.7 3.9 4 0 0 4 4 4 3 Sel1 repeat TPR_11 PF13414.1 EIE78742.1 - 0.00043 19.8 3.7 0.22 11.2 0.2 2.8 2 0 0 2 2 2 2 TPR repeat TPR_16 PF13432.1 EIE78742.1 - 0.11 13.2 0.2 14 6.4 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat CCG PF02754.11 EIE78743.1 - 0.0082 16.1 0.0 0.0087 16.0 0.0 1.0 1 0 0 1 1 1 1 Cysteine-rich domain AAA_13 PF13166.1 EIE78745.1 - 0.044 12.2 43.8 0.021 13.3 14.7 2.7 2 0 0 2 2 2 0 AAA domain GAS PF13851.1 EIE78745.1 - 0.4 9.8 60.3 0.58 9.3 19.3 4.1 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.4 EIE78745.1 - 2.9 7.7 60.9 2.3 8.0 18.0 3.7 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ADIP PF11559.3 EIE78745.1 - 4.2 7.2 61.9 0.17 11.7 10.2 5.6 2 1 3 5 5 5 0 Afadin- and alpha -actinin-Binding DUF3584 PF12128.3 EIE78745.1 - 4.7 4.4 51.3 0.24 8.6 25.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) p450 PF00067.17 EIE78746.1 - 5e-36 124.2 1.0 1.1e-35 123.1 0.7 1.5 1 1 0 1 1 1 1 Cytochrome P450 Topoisom_bac PF01131.15 EIE78747.1 - 9.6e-92 307.8 0.0 1.2e-91 307.6 0.0 1.0 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 EIE78747.1 - 6.3e-09 35.7 0.0 1.3e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Toprim domain F-box-like PF12937.2 EIE78748.1 - 1e-09 37.9 0.1 3e-09 36.4 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIE78748.1 - 0.00031 20.3 0.1 0.0018 17.8 0.0 2.3 3 0 0 3 3 3 1 F-box domain TPT PF03151.11 EIE78750.1 - 2.4e-16 59.7 34.0 2.8e-16 59.5 9.1 2.5 2 1 0 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.6 EIE78750.1 - 1.1e-10 40.8 28.3 2.3e-10 39.9 19.6 1.4 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EIE78750.1 - 3.4e-07 30.3 33.0 0.00083 19.3 8.5 3.0 2 1 1 3 3 3 2 EamA-like transporter family EmrE PF13536.1 EIE78750.1 - 0.0048 17.0 4.8 0.0048 17.0 3.3 3.4 2 1 1 3 3 3 2 Multidrug resistance efflux transporter DUF2962 PF11176.3 EIE78752.1 - 1.7e-28 99.1 8.8 5.8e-22 77.9 0.6 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF2962) IL4 PF00727.13 EIE78752.1 - 0.0059 16.4 0.2 0.0088 15.9 0.2 1.3 1 0 0 1 1 1 1 Interleukin 4 DUF2570 PF10828.3 EIE78752.1 - 0.27 10.8 2.1 1.2 8.7 1.4 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2570) Acyltransferase PF01553.16 EIE78753.1 - 8.3e-12 44.6 0.1 1.1e-10 41.0 0.0 2.4 1 1 0 1 1 1 1 Acyltransferase Rtt106 PF08512.7 EIE78754.1 - 8.2e-24 83.4 0.0 1.4e-23 82.6 0.0 1.4 1 0 0 1 1 1 1 Histone chaperone Rttp106-like DUF2722 PF10846.3 EIE78754.1 - 0.96 8.4 13.4 1.4 7.8 9.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Hid1 PF12722.2 EIE78754.1 - 3.4 5.2 6.9 3.9 5.0 4.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein BRE1 PF08647.6 EIE78755.1 - 1.6e-07 31.1 10.6 1.6e-07 31.1 7.3 5.7 6 1 1 7 7 7 1 BRE1 E3 ubiquitin ligase Reo_sigmaC PF04582.7 EIE78755.1 - 0.32 10.1 11.3 1.1 8.3 3.9 2.8 2 1 0 2 2 2 0 Reovirus sigma C capsid protein Inhibitor_I42 PF09394.5 EIE78756.1 - 0.0088 16.3 0.0 0.0095 16.2 0.0 1.0 1 0 0 1 1 1 1 Chagasin family peptidase inhibitor I42 C2-set_2 PF08205.7 EIE78756.1 - 0.084 12.7 0.6 0.21 11.4 0.2 1.7 1 1 1 2 2 2 0 CD80-like C2-set immunoglobulin domain Mito_carr PF00153.22 EIE78757.1 - 5.4e-68 224.7 2.4 3.4e-24 84.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Glyco_hydro_88 PF07470.8 EIE78757.1 - 0.083 11.9 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl Hydrolase Family 88 Rib_5-P_isom_A PF06026.9 EIE78758.1 - 6.9e-06 25.4 0.0 0.00021 20.6 0.0 2.0 1 1 1 2 2 2 2 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) FUN14 PF04930.10 EIE78759.1 - 0.14 12.4 0.1 0.18 12.1 0.1 1.2 1 0 0 1 1 1 0 FUN14 family CCDC92 PF14916.1 EIE78760.1 - 0.013 15.1 0.0 0.028 14.0 0.0 1.6 1 0 0 1 1 1 0 Coiled-coil domain of unknown function Rab5-bind PF09311.6 EIE78760.1 - 0.013 15.3 0.8 0.013 15.3 0.5 1.4 2 0 0 2 2 2 0 Rabaptin-like protein DivIC PF04977.10 EIE78760.1 - 0.068 12.6 2.5 0.14 11.7 1.7 1.4 1 0 0 1 1 1 0 Septum formation initiator DUF4140 PF13600.1 EIE78760.1 - 0.36 11.2 1.5 0.79 10.2 1.0 1.6 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Lebercilin PF15619.1 EIE78760.1 - 1.5 8.2 4.8 0.21 11.0 0.7 1.5 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DFF-C PF09033.5 EIE78764.1 - 0.0087 15.9 0.3 0.01 15.6 0.2 1.2 1 0 0 1 1 1 1 DNA Fragmentation factor 45kDa, C terminal domain FTR1 PF03239.9 EIE78766.1 - 1.7e-76 257.1 14.3 2e-76 256.8 9.9 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family Herpes_glycop PF01528.11 EIE78766.1 - 0.00052 18.8 0.5 0.00052 18.8 0.3 2.0 2 0 0 2 2 2 1 Herpesvirus glycoprotein M Fijivirus_P9-2 PF06837.6 EIE78766.1 - 0.032 13.3 0.0 0.07 12.2 0.0 1.6 1 0 0 1 1 1 0 Fijivirus P9-2 protein DUF1469 PF07332.6 EIE78766.1 - 0.033 13.9 9.6 0.087 12.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) DUF1211 PF06736.6 EIE78766.1 - 0.037 14.1 1.7 0.051 13.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1211) Yos1 PF08571.5 EIE78766.1 - 0.054 13.5 0.1 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 Yos1-like PrgI PF12666.2 EIE78766.1 - 0.078 13.1 0.3 0.078 13.1 0.2 3.2 4 0 0 4 4 4 0 PrgI family protein SPC25 PF06703.6 EIE78766.1 - 0.42 10.1 2.8 0.44 10.1 0.0 2.3 3 0 0 3 3 3 0 Microsomal signal peptidase 25 kDa subunit (SPC25) YfhO PF09586.5 EIE78766.1 - 1.9 6.4 9.1 4.1 5.2 1.7 2.2 2 1 0 2 2 2 0 Bacterial membrane protein YfhO Wzy_C PF04932.10 EIE78766.1 - 7.5 6.3 12.3 0.11 12.3 1.0 2.4 2 1 0 2 2 2 0 O-Antigen ligase Cu-oxidase_2 PF07731.9 EIE78767.1 - 2.6e-44 150.1 6.0 1.5e-41 141.1 0.0 3.4 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EIE78767.1 - 1e-37 128.4 11.0 2.3e-36 124.1 2.8 3.5 3 2 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 EIE78767.1 - 2e-32 112.3 7.2 2.9e-31 108.5 0.4 2.7 3 0 0 3 3 3 2 Multicopper oxidase Hexokinase_2 PF03727.11 EIE78768.1 - 3.2e-51 173.8 0.0 4.3e-51 173.4 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EIE78768.1 - 3.7e-49 166.8 0.2 6.4e-49 166.0 0.1 1.4 1 0 0 1 1 1 1 Hexokinase WD40 PF00400.27 EIE78769.1 - 3.6e-14 51.9 0.1 2.8e-06 26.9 0.0 3.0 3 0 0 3 3 3 2 WD domain, G-beta repeat MSV199 PF10553.4 EIE78769.1 - 0.077 12.8 2.6 0.061 13.1 0.8 1.7 1 1 1 2 2 2 0 MSV199 domain SNF2_N PF00176.18 EIE78771.1 - 4.1e-62 209.6 0.3 6.4e-62 209.0 0.2 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EIE78771.1 - 9.5e-07 28.8 3.9 1.1e-06 28.6 0.0 2.8 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit HATPase_c PF02518.21 EIE78772.1 - 1.2e-28 99.0 0.0 2.6e-28 97.9 0.0 1.6 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TFIIA PF03153.8 EIE78772.1 - 0.069 13.0 24.0 0.12 12.2 13.5 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Phostensin_N PF13916.1 EIE78772.1 - 2.9 7.9 10.0 0.76 9.8 0.7 2.8 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal EI24 PF07264.6 EIE78773.1 - 5.4e-07 29.2 1.1 7.5e-07 28.7 0.8 1.2 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF4112 PF13430.1 EIE78773.1 - 0.077 12.9 0.5 3.2 7.7 0.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4112) Pkinase PF00069.20 EIE78774.1 - 6.6e-19 68.0 0.3 6.1e-11 41.9 0.1 2.7 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIE78774.1 - 2e-08 33.6 2.1 9.6e-07 28.1 0.5 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 EIE78774.1 - 0.0022 17.1 0.2 0.0045 16.0 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4083 PF13314.1 EIE78774.1 - 0.22 11.4 0.0 0.22 11.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) Cyclin_N PF00134.18 EIE78775.1 - 2.5e-36 124.0 1.3 4.9e-34 116.6 0.1 2.5 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 EIE78775.1 - 1e-25 89.9 0.4 2.9e-25 88.4 0.1 2.0 2 0 0 2 2 2 1 Cyclin, C-terminal domain eIF-3c_N PF05470.7 EIE78776.1 - 0.16 10.0 4.0 0.19 9.7 2.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus SNF5 PF04855.7 EIE78777.1 - 1.5e-56 191.5 3.8 1.5e-56 191.5 2.6 3.0 2 1 0 2 2 2 1 SNF5 / SMARCB1 / INI1 Pkinase PF00069.20 EIE78778.1 - 9.9e-74 247.7 0.0 1.3e-73 247.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE78778.1 - 3.5e-40 137.7 0.0 4.5e-40 137.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE78778.1 - 5e-10 38.8 0.0 9.1e-10 37.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EIE78778.1 - 0.011 15.5 0.0 0.022 14.5 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ribosomal_L32p PF01783.18 EIE78778.1 - 0.019 15.1 0.2 0.06 13.5 0.1 1.9 1 0 0 1 1 1 0 Ribosomal L32p protein family Kdo PF06293.9 EIE78778.1 - 0.025 13.6 0.0 0.051 12.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EIE78778.1 - 0.062 12.6 0.0 0.13 11.5 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Sugar_tr PF00083.19 EIE78781.1 - 1.5e-91 307.2 38.9 1.5e-90 303.9 27.0 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIE78781.1 - 1.8e-36 125.5 57.7 5.4e-31 107.5 21.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Erythrovirus_X PF06795.6 EIE78781.1 - 1.9 8.5 7.2 1.3 9.0 0.7 3.2 2 1 1 3 3 3 0 Erythrovirus X protein COMPASS-Shg1 PF05205.7 EIE78782.1 - 1.9e-13 50.6 1.6 3.8e-11 43.2 0.1 2.0 1 1 1 2 2 2 2 COMPASS (Complex proteins associated with Set1p) component shg1 DUF3731 PF12531.3 EIE78782.1 - 0.011 15.3 0.1 0.012 15.2 0.1 1.1 1 0 0 1 1 1 0 DNA-K related protein PB1 PF00564.19 EIE78782.1 - 0.039 13.6 0.2 1.3 8.7 0.0 2.3 1 1 0 2 2 2 0 PB1 domain PPDK_N PF01326.14 EIE78782.1 - 0.062 12.3 0.1 0.069 12.1 0.0 1.1 1 0 0 1 1 1 0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain FUSC-like PF12805.2 EIE78782.1 - 0.074 11.9 0.2 0.087 11.7 0.1 1.1 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS Fungal_trans PF04082.13 EIE78783.1 - 1.9e-29 102.3 1.9 1.2e-28 99.6 0.2 2.5 2 0 0 2 2 2 2 Fungal specific transcription factor domain Far-17a_AIG1 PF04750.9 EIE78784.1 - 0.014 14.5 2.3 0.015 14.4 1.6 1.1 1 0 0 1 1 1 0 FAR-17a/AIG1-like protein RBP_receptor PF14752.1 EIE78784.1 - 0.13 10.5 3.3 0.15 10.3 2.3 1.0 1 0 0 1 1 1 0 Retinol binding protein receptor TctB PF07331.6 EIE78784.1 - 0.19 11.3 5.9 0.2 11.3 4.1 1.1 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family Intg_mem_TP0381 PF09529.5 EIE78784.1 - 0.26 10.4 6.0 0.28 10.3 4.1 1.0 1 0 0 1 1 1 0 Integral membrane protein (intg_mem_TP0381) Tmemb_9 PF05434.6 EIE78784.1 - 8 6.1 5.9 5.3 6.7 3.2 1.4 1 1 0 1 1 1 0 TMEM9 Syntaxin_2 PF14523.1 EIE78785.1 - 1.1e-27 96.0 9.4 1.1e-27 96.0 6.5 2.6 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.14 EIE78785.1 - 1.2e-14 53.7 2.0 1.2e-14 53.7 1.4 3.3 3 1 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 EIE78785.1 - 7.2e-09 35.7 3.4 7.2e-09 35.7 2.4 3.2 2 1 0 2 2 2 1 Syntaxin MCPsignal PF00015.16 EIE78785.1 - 0.0014 18.2 3.1 0.0014 18.2 2.2 2.3 1 1 1 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain LMBR1 PF04791.11 EIE78785.1 - 0.0023 16.6 4.6 0.0037 15.9 3.2 1.3 1 1 0 1 1 1 1 LMBR1-like membrane protein TagA PF12561.3 EIE78785.1 - 0.13 12.2 0.2 0.13 12.2 0.1 2.5 1 1 0 2 2 2 0 ToxR activated gene A lipoprotein Brix PF04427.13 EIE78786.1 - 3e-40 137.9 1.2 3.8e-40 137.6 0.9 1.1 1 0 0 1 1 1 1 Brix domain RIO1 PF01163.17 EIE78786.1 - 0.055 12.8 0.0 0.092 12.0 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Cys_Met_Meta_PP PF01053.15 EIE78787.1 - 5.3e-154 512.1 0.3 6e-154 512.0 0.2 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EIE78787.1 - 1.7e-07 30.3 0.3 1.9e-06 26.8 0.1 2.1 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EIE78787.1 - 1.1e-06 27.8 0.1 2e-06 26.9 0.1 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EIE78787.1 - 3.5e-05 23.1 0.4 8.3e-05 21.8 0.3 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EIE78787.1 - 4e-05 22.8 0.8 7.9e-05 21.8 0.2 1.7 1 1 1 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family GDC-P PF02347.11 EIE78787.1 - 0.0054 15.4 0.0 0.0082 14.8 0.0 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein Alliinase_C PF04864.8 EIE78787.1 - 0.0073 15.0 0.0 0.0099 14.5 0.0 1.2 1 0 0 1 1 1 1 Allinase Rcd1 PF04078.8 EIE78788.1 - 3.1e-129 429.4 2.4 4e-129 429.0 1.6 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like CDK2AP PF09806.4 EIE78788.1 - 0.23 11.6 9.2 0.23 11.6 5.2 1.8 1 1 1 2 2 2 0 Cyclin-dependent kinase 2-associated protein P_C PF06640.6 EIE78788.1 - 0.31 11.0 3.3 0.53 10.2 2.3 1.3 1 0 0 1 1 1 0 P protein C-terminus Ribosomal_60s PF00428.14 EIE78788.1 - 4.8 7.6 14.2 0.28 11.6 6.2 1.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein TFIIA PF03153.8 EIE78788.1 - 5.1 6.8 8.6 7.1 6.4 6.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pkinase PF00069.20 EIE78789.1 - 5e-57 193.0 0.3 7.9e-57 192.3 0.2 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE78789.1 - 2.1e-41 141.7 0.3 3.1e-41 141.1 0.2 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase IncA PF04156.9 EIE78789.1 - 8.8 5.8 8.7 17 4.9 6.0 1.4 1 0 0 1 1 1 0 IncA protein BING4CT PF08149.6 EIE78790.1 - 2.9e-38 129.2 0.0 8.2e-37 124.5 0.0 3.2 4 0 0 4 4 4 1 BING4CT (NUC141) domain WD40 PF00400.27 EIE78790.1 - 4.2e-11 42.2 0.0 7.8e-07 28.7 0.0 4.5 5 0 0 5 5 5 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 EIE78790.1 - 6.4e-06 25.2 0.0 9.1e-06 24.7 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region PQQ_2 PF13360.1 EIE78790.1 - 0.0044 16.5 0.0 0.026 13.9 0.0 2.2 2 1 0 2 2 2 1 PQQ-like domain Hexokinase_2 PF03727.11 EIE78791.1 - 2.6e-33 115.2 0.3 1.3e-19 70.3 0.0 2.1 1 1 1 2 2 2 2 Hexokinase Hexokinase_1 PF00349.16 EIE78791.1 - 5.8e-10 38.8 0.0 8.7e-10 38.2 0.0 1.3 1 0 0 1 1 1 1 Hexokinase RicinB_lectin_2 PF14200.1 EIE78792.1 - 5e-09 36.4 0.3 1.2e-06 28.8 0.1 2.5 2 1 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 EIE78792.1 - 8.1e-08 32.3 0.1 1.5e-06 28.2 0.1 2.7 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain DUF3122 PF11320.3 EIE78792.1 - 0.03 14.2 0.4 0.07 13.0 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3122) Adaptin_N PF01602.15 EIE78794.1 - 2.9e-129 431.7 8.4 3.9e-129 431.3 5.8 1.1 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 EIE78794.1 - 3.8e-10 39.9 6.2 0.00033 20.8 0.0 4.3 4 1 0 4 4 4 2 HEAT repeats Cnd1 PF12717.2 EIE78794.1 - 1.3e-07 31.6 1.2 0.00033 20.5 0.0 3.7 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 EIE78794.1 - 1.4e-06 27.9 4.2 0.16 12.1 0.0 7.0 7 0 0 7 7 7 1 HEAT repeat HEAT_EZ PF13513.1 EIE78794.1 - 0.00063 20.1 5.0 2.9 8.5 0.1 5.2 4 1 2 6 6 6 1 HEAT-like repeat Cohesin_HEAT PF12765.2 EIE78794.1 - 0.013 15.4 0.1 0.082 12.8 0.0 2.4 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion Arm PF00514.18 EIE78794.1 - 0.24 11.2 6.3 0.69 9.8 0.3 4.2 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat Nop14 PF04147.7 EIE78794.1 - 4.3 5.1 16.5 7.1 4.4 11.4 1.3 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 EIE78794.1 - 7.8 4.8 16.2 12 4.2 11.2 1.2 1 0 0 1 1 1 0 Daxx Family NOA36 PF06524.7 EIE78794.1 - 8.7 5.5 13.7 29 3.7 7.9 2.5 3 0 0 3 3 3 0 NOA36 protein Dynamin_M PF01031.15 EIE78795.1 - 5.5e-106 353.6 0.1 5.5e-106 353.6 0.1 2.0 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 EIE78795.1 - 1.4e-56 190.9 0.0 3.5e-56 189.6 0.0 1.7 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 EIE78795.1 - 1.2e-29 102.0 6.1 3.6e-29 100.4 4.3 1.9 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EIE78795.1 - 0.00024 21.0 1.3 0.0032 17.4 0.1 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EIE78795.1 - 0.011 16.2 0.0 0.033 14.6 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein Baculo_p74 PF04583.7 EIE78795.1 - 0.66 9.1 4.8 1.4 8.0 0.2 2.8 3 0 0 3 3 3 0 Baculoviridae p74 conserved region DUF755 PF05501.6 EIE78795.1 - 1.2 9.2 6.4 0.38 10.8 0.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Ubiquitin_2 PF14560.1 EIE78796.1 - 0.0094 16.1 0.0 0.013 15.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain Pyrophosphatase PF00719.14 EIE78797.1 - 1.1e-51 174.3 0.3 1.5e-51 173.9 0.2 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase Malate_synthase PF01274.17 EIE78798.1 - 1.5e-227 755.7 0.1 1.7e-227 755.6 0.1 1.0 1 0 0 1 1 1 1 Malate synthase HpcH_HpaI PF03328.9 EIE78798.1 - 0.016 14.1 0.0 0.033 13.0 0.0 1.5 1 0 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family Glyco_transf_49 PF13896.1 EIE78799.1 - 5.5e-38 130.8 1.9 2.5e-29 102.4 0.3 2.0 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glyco_tranf_2_2 PF10111.4 EIE78799.1 - 0.018 14.1 0.0 0.038 13.0 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase like family 2 DUF1014 PF06244.7 EIE78800.1 - 3.4e-28 98.3 17.8 3.4e-28 98.3 12.3 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF1014) DUF1139 PF06599.6 EIE78801.1 - 0.034 13.3 0.1 0.036 13.2 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1139) Ribosomal_L37e PF01907.14 EIE78802.1 - 5.5e-26 90.1 12.6 1.1e-25 89.2 8.7 1.5 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.2 EIE78802.1 - 0.00027 20.6 2.9 0.00043 20.0 2.0 1.3 1 0 0 1 1 1 1 Double zinc ribbon SelR PF01641.13 EIE78802.1 - 0.0077 15.9 1.2 0.011 15.3 0.9 1.5 1 1 0 1 1 1 1 SelR domain HypA PF01155.14 EIE78802.1 - 0.029 14.0 1.0 0.041 13.5 0.7 1.2 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-RING_5 PF14634.1 EIE78802.1 - 0.034 13.8 4.0 0.052 13.2 2.8 1.3 1 0 0 1 1 1 0 zinc-RING finger domain C1_1 PF00130.17 EIE78802.1 - 0.046 13.4 3.6 0.084 12.6 2.5 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Ribosomal_S14 PF00253.16 EIE78802.1 - 0.16 11.3 6.9 0.83 9.0 0.1 2.5 1 1 1 2 2 2 0 Ribosomal protein S14p/S29e Ogr_Delta PF04606.7 EIE78802.1 - 0.21 11.2 3.3 0.66 9.6 0.2 2.3 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger GFA PF04828.9 EIE78802.1 - 0.35 10.8 4.3 1.6 8.7 2.5 2.1 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zf-ribbon_3 PF13248.1 EIE78802.1 - 0.48 9.6 4.1 2.8 7.2 3.0 1.9 1 1 1 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 EIE78802.1 - 0.61 9.6 5.3 6.9 6.2 3.7 2.1 1 1 1 2 2 2 0 zinc-ribbon domain zf-C3HC4_2 PF13923.1 EIE78802.1 - 0.62 10.1 5.1 0.98 9.4 3.5 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIE78802.1 - 0.9 9.2 5.1 1.4 8.6 3.5 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) YhfH PF14149.1 EIE78802.1 - 3.1 7.6 6.0 3.1 7.6 1.3 2.2 1 1 1 2 2 2 0 YhfH-like protein RNA_POL_M_15KD PF02150.11 EIE78802.1 - 4.3 7.1 5.9 32 4.3 4.2 2.0 1 1 0 1 1 1 0 RNA polymerases M/15 Kd subunit zf-HYPF PF07503.7 EIE78802.1 - 8.8 5.8 7.6 5.2 6.5 3.1 2.1 2 1 1 3 3 3 0 HypF finger CAS_CSE1 PF03378.10 EIE78803.1 - 4.6e-07 28.4 1.8 0.0013 17.0 0.0 3.4 3 1 0 3 3 3 2 CAS/CSE protein, C-terminus RIX1 PF08167.7 EIE78803.1 - 0.083 12.5 0.0 0.46 10.1 0.0 2.3 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis SDA1 PF05285.7 EIE78803.1 - 2.2 7.4 4.0 3.1 6.9 2.8 1.1 1 0 0 1 1 1 0 SDA1 Lyase_1 PF00206.15 EIE78804.1 - 1.7e-20 73.4 0.0 2.6e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 EIE78804.1 - 5.4e-15 55.1 0.0 1.3e-14 53.9 0.0 1.7 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus DUF1331 PF07048.6 EIE78804.1 - 0.0085 15.5 0.2 0.016 14.6 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1331) Sec16_C PF12931.2 EIE78805.1 - 2.3e-46 158.8 0.0 3.2e-46 158.3 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.2 EIE78805.1 - 5.5e-15 55.3 0.0 1e-14 54.5 0.0 1.5 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region DZR PF12773.2 EIE78805.1 - 0.0011 18.7 0.4 0.0022 17.7 0.3 1.5 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.1 EIE78805.1 - 0.09 12.2 5.7 0.038 13.4 2.0 1.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 EIE78805.1 - 0.68 9.2 3.9 0.53 9.5 1.2 1.9 2 0 0 2 2 2 0 zinc-ribbon domain Sulfate_transp PF00916.15 EIE78806.1 - 8.1e-65 218.5 11.2 8.1e-65 218.5 7.7 1.4 2 0 0 2 2 2 1 Sulfate transporter family DUF2254 PF10011.4 EIE78806.1 - 0.02 13.3 5.7 0.0099 14.3 2.1 1.8 1 1 0 1 1 1 0 Predicted membrane protein (DUF2254) STAS PF01740.16 EIE78807.1 - 7.2e-11 41.5 0.0 8.3e-11 41.3 0.0 1.1 1 0 0 1 1 1 1 STAS domain GATase PF00117.23 EIE78809.1 - 2.6e-09 36.8 0.2 0.0012 18.3 0.2 2.1 1 1 1 2 2 2 2 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EIE78809.1 - 6.3e-06 25.7 1.5 0.047 13.1 0.1 2.5 1 1 1 2 2 2 2 Peptidase C26 HTS PF04204.11 EIE78809.1 - 0.0041 15.8 0.0 0.74 8.4 0.0 2.1 1 1 1 2 2 2 2 Homoserine O-succinyltransferase GATase_3 PF07685.9 EIE78809.1 - 0.011 15.3 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain RVT_1 PF00078.22 EIE78810.1 - 5.5e-23 81.4 0.0 1.3e-22 80.2 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 EIE78811.1 - 1.6e-18 66.8 0.3 4.5e-18 65.3 0.2 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_1 PF03184.14 EIE78812.1 - 2.1e-25 89.1 0.4 3.9e-25 88.2 0.3 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EIE78812.1 - 0.0048 16.6 0.0 0.011 15.5 0.0 1.6 1 1 0 1 1 1 1 DDE superfamily endonuclease TPM PF04536.9 EIE78812.1 - 0.099 12.5 0.0 0.4 10.5 0.0 2.0 1 1 0 1 1 1 0 TLP18.3, Psb32 and MOLO-1 founding proteins of phosphatase DDE_1 PF03184.14 EIE78813.1 - 2.1e-25 89.1 0.4 3.9e-25 88.2 0.3 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EIE78813.1 - 0.0048 16.6 0.0 0.011 15.5 0.0 1.6 1 1 0 1 1 1 1 DDE superfamily endonuclease TPM PF04536.9 EIE78813.1 - 0.099 12.5 0.0 0.4 10.5 0.0 2.0 1 1 0 1 1 1 0 TLP18.3, Psb32 and MOLO-1 founding proteins of phosphatase RVT_1 PF00078.22 EIE78814.1 - 5.3e-31 107.6 0.0 9e-31 106.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EIE78814.1 - 2.4e-11 43.2 0.3 8.6e-11 41.4 0.2 2.0 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase HTH_29 PF13551.1 EIE78816.1 - 8.5e-10 38.7 0.0 2.1e-09 37.5 0.0 1.6 1 1 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.1 EIE78816.1 - 1.4e-07 32.1 0.0 2.8e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.1 EIE78816.1 - 0.00019 21.3 0.2 0.00031 20.6 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain PAX PF00292.13 EIE78816.1 - 0.00087 18.9 0.0 0.0015 18.2 0.0 1.3 1 0 0 1 1 1 1 'Paired box' domain HTH_Tnp_1 PF01527.15 EIE78816.1 - 0.014 15.3 0.3 0.029 14.3 0.2 1.6 1 1 0 1 1 1 0 Transposase MerR_1 PF13411.1 EIE78816.1 - 0.044 13.5 2.8 0.32 10.7 0.5 2.7 2 1 0 2 2 2 0 MerR HTH family regulatory protein HTH_10 PF04967.7 EIE78816.1 - 0.044 13.3 0.1 5.7 6.6 0.0 3.0 3 0 0 3 3 3 0 HTH DNA binding domain NTPase_1 PF03266.10 EIE78816.1 - 0.052 13.2 0.0 0.085 12.5 0.0 1.3 1 0 0 1 1 1 0 NTPase LZ_Tnp_IS481 PF13011.1 EIE78816.1 - 0.071 13.4 0.1 0.17 12.2 0.0 1.6 2 0 0 2 2 2 0 leucine-zipper of insertion element IS481 HTH_Tnp_Tc3_2 PF01498.13 EIE78816.1 - 0.12 12.5 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Transposase DivIC PF04977.10 EIE78818.1 - 0.0033 16.8 2.4 0.0087 15.5 1.7 1.6 1 0 0 1 1 1 1 Septum formation initiator Herpes_BLRF2 PF05812.7 EIE78818.1 - 0.071 12.9 0.2 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein SlyX PF04102.7 EIE78818.1 - 0.13 12.6 3.2 0.28 11.5 2.2 1.5 1 0 0 1 1 1 0 SlyX Lebercilin PF15619.1 EIE78818.1 - 0.27 10.6 6.1 0.051 12.9 1.8 1.5 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Gag_spuma PF03276.9 EIE78818.1 - 0.35 9.1 8.5 0.46 8.7 5.9 1.1 1 0 0 1 1 1 0 Spumavirus gag protein AMP-binding PF00501.23 EIE78819.1 - 7.7e-49 166.2 0.1 2e-26 92.3 0.0 3.5 3 1 0 3 3 3 3 AMP-binding enzyme DMAP_binding PF06464.6 EIE78820.1 - 1.8e-10 41.3 8.7 1.5e-09 38.3 6.0 2.2 1 1 0 1 1 1 1 DMAP1-binding Domain GvpG PF05120.7 EIE78820.1 - 0.00067 19.4 0.5 0.00067 19.4 0.3 1.6 2 0 0 2 2 2 1 Gas vesicle protein G PAT1 PF09770.4 EIE78820.1 - 0.0023 16.2 43.2 0.0029 15.9 30.0 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Spt20 PF12090.3 EIE78820.1 - 0.021 14.1 5.0 0.032 13.5 3.4 1.4 1 1 0 1 1 1 0 Spt20 family Ala_racemase_N PF01168.15 EIE78821.1 - 1.9e-36 125.6 0.0 1.3e-27 96.8 0.0 2.0 1 1 1 2 2 2 2 Alanine racemase, N-terminal domain Sec8_exocyst PF04048.9 EIE78824.1 - 0.099 12.2 1.4 6.7 6.3 0.5 2.3 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain PC_rep PF01851.17 EIE78825.1 - 3e-42 140.5 14.1 1.3e-06 28.2 0.1 9.3 8 0 0 8 8 8 7 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EIE78825.1 - 4.4e-15 55.7 1.2 7.8e-10 38.9 0.0 4.8 2 1 3 5 5 5 3 HEAT repeats HEAT PF02985.17 EIE78825.1 - 8.1e-07 28.6 0.1 2.2 8.5 0.1 5.6 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.1 EIE78825.1 - 0.011 16.2 3.0 0.42 11.1 0.1 4.5 4 1 2 6 6 6 0 HEAT-like repeat DUF2228 PF10228.4 EIE78825.1 - 0.7 9.3 5.7 2.1 7.8 0.7 2.9 2 1 0 2 2 2 0 Uncharacterised conserved protein (DUF2228) MBOAT PF03062.14 EIE78826.1 - 3.1e-15 56.1 0.6 5.4e-15 55.3 0.4 1.4 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Sec1 PF00995.18 EIE78827.1 - 1.4e-86 291.3 0.1 1.7e-86 291.0 0.0 1.1 1 0 0 1 1 1 1 Sec1 family Sec1 PF00995.18 EIE78828.1 - 2.8e-05 22.9 0.2 3.6e-05 22.6 0.1 1.1 1 0 0 1 1 1 1 Sec1 family DUF572 PF04502.8 EIE78829.1 - 6.5e-87 291.7 14.0 7.8e-87 291.5 9.7 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) zf-ribbon_3 PF13248.1 EIE78829.1 - 0.017 14.3 0.5 4.6 6.5 0.0 2.3 2 0 0 2 2 2 0 zinc-ribbon domain DUF866 PF05907.8 EIE78829.1 - 0.021 14.2 0.1 0.043 13.3 0.1 1.5 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) zf-dskA_traR PF01258.12 EIE78829.1 - 0.078 12.7 1.7 0.14 11.9 0.2 2.0 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger zf-FCS PF06467.9 EIE78829.1 - 0.1 12.2 0.4 0.59 9.8 0.1 2.1 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zinc_ribbon_5 PF13719.1 EIE78829.1 - 0.1 12.2 1.7 2.5 7.7 0.2 2.8 3 0 0 3 3 3 0 zinc-ribbon domain zf-CSL PF05207.8 EIE78829.1 - 0.12 11.9 0.3 0.34 10.4 0.2 1.8 1 0 0 1 1 1 0 CSL zinc finger zinc_ribbon_4 PF13717.1 EIE78829.1 - 0.12 12.0 1.8 2.9 7.6 0.2 2.8 3 0 0 3 3 3 0 zinc-ribbon domain DNA_RNApol_7kD PF03604.8 EIE78829.1 - 0.13 11.7 1.1 12 5.4 0.0 2.5 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit UPF0547 PF10571.4 EIE78829.1 - 0.2 11.3 1.4 1.6 8.5 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Rubredoxin PF00301.15 EIE78829.1 - 0.26 11.2 2.5 2 8.3 1.7 2.4 1 1 0 1 1 1 0 Rubredoxin Terminase_2 PF03592.11 EIE78829.1 - 0.34 11.1 3.5 0.78 10.0 2.4 1.5 1 0 0 1 1 1 0 Terminase small subunit CpXC PF14353.1 EIE78829.1 - 0.36 10.7 4.0 10 6.0 0.0 2.8 2 1 0 2 2 2 0 CpXC protein zf-NADH-PPase PF09297.6 EIE78829.1 - 0.49 9.9 3.0 1.7 8.2 0.1 2.3 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain zf-DNA_Pol PF08996.5 EIE78829.1 - 0.85 8.9 4.0 9.5 5.5 0.1 2.8 1 1 3 4 4 4 0 DNA Polymerase alpha zinc finger TF_Zn_Ribbon PF08271.7 EIE78829.1 - 1.1 8.6 6.3 2.4 7.5 0.2 3.1 3 0 0 3 3 3 0 TFIIB zinc-binding DUF3323 PF11796.3 EIE78829.1 - 1.2 8.3 5.4 1.7 7.9 3.8 1.2 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) TFIIA_gamma_N PF02268.11 EIE78830.1 - 2.8e-26 90.8 0.0 4.2e-26 90.2 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.9 EIE78830.1 - 4.4e-26 90.4 1.5 5.9e-26 90.0 1.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit HECT PF00632.20 EIE78831.1 - 2.3e-93 312.8 0.0 3e-93 312.4 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 EIE78831.1 - 1.6e-34 117.3 20.1 2.4e-12 46.4 0.3 3.8 4 0 0 4 4 4 3 WW domain RabGAP-TBC PF00566.13 EIE78832.1 - 1.6e-41 142.1 0.4 1.6e-41 142.1 0.3 1.9 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Transketolase_N PF00456.16 EIE78832.1 - 0.047 12.4 0.2 0.064 12.0 0.1 1.2 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain MBF1 PF08523.5 EIE78833.1 - 1.4e-21 76.2 1.8 2.3e-21 75.5 1.3 1.4 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 EIE78833.1 - 2.5e-13 49.6 0.3 4.5e-13 48.8 0.2 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.1 EIE78833.1 - 0.00027 21.0 0.0 0.00052 20.1 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.2 EIE78833.1 - 0.00049 20.0 0.1 0.00075 19.4 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain RrnaAD PF00398.15 EIE78833.1 - 0.0054 15.7 0.0 0.0071 15.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase TAF4 PF05236.9 EIE78833.1 - 0.065 12.5 0.2 0.08 12.1 0.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family TAFII55_N PF04658.8 EIE78835.1 - 0.033 13.6 0.4 0.042 13.3 0.3 1.1 1 0 0 1 1 1 0 TAFII55 protein conserved region Myc_N PF01056.13 EIE78835.1 - 0.11 11.6 2.5 0.14 11.3 1.7 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Ribosomal_L19e PF01280.15 EIE78836.1 - 4.2e-60 201.7 10.3 4.2e-60 201.7 7.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L19e DUF4602 PF15375.1 EIE78836.1 - 0.31 11.1 7.6 0.53 10.3 5.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4602) NMO PF03060.10 EIE78837.1 - 2.4e-13 49.9 0.0 2.4e-13 49.9 0.0 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase WD40 PF00400.27 EIE78838.1 - 9.5e-55 180.6 7.0 1e-09 37.9 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat Tup_N PF08581.5 EIE78838.1 - 0.0012 19.0 2.6 0.0022 18.1 1.8 1.5 1 0 0 1 1 1 1 Tup N-terminal Nucleoporin_N PF08801.6 EIE78838.1 - 0.0014 17.5 0.2 0.081 11.6 0.1 2.6 1 1 2 3 3 3 2 Nup133 N terminal like Gmad1 PF10647.4 EIE78838.1 - 0.0018 17.7 0.1 0.0029 17.0 0.1 1.4 1 0 0 1 1 1 1 Lipoprotein LpqB beta-propeller domain Cytochrom_D1 PF02239.11 EIE78838.1 - 0.0043 15.4 0.2 0.05 11.8 0.0 2.2 2 1 1 3 3 3 2 Cytochrome D1 heme domain PQQ_2 PF13360.1 EIE78838.1 - 0.0087 15.5 0.1 3.2 7.1 0.1 3.0 2 1 0 2 2 2 1 PQQ-like domain Nbas_N PF15492.1 EIE78838.1 - 0.037 13.1 0.0 0.9 8.5 0.0 2.4 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.3 EIE78838.1 - 0.042 11.9 0.3 0.63 8.1 0.0 2.8 2 1 1 4 4 4 0 Nucleoporin Nup120/160 MMS1_N PF10433.4 EIE78838.1 - 0.042 11.9 0.0 1.8 6.5 0.0 2.2 1 1 1 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term DUF4600 PF15372.1 EIE78838.1 - 0.096 12.9 0.4 0.34 11.1 0.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4600) Proteasome_A_N PF10584.4 EIE78838.1 - 0.8 9.0 3.0 14 5.0 0.1 3.3 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature EAF PF09816.4 EIE78839.1 - 1.3e-06 28.3 0.1 3.1e-06 27.1 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor FAM70 PF14967.1 EIE78839.1 - 0.031 13.5 0.5 0.062 12.4 0.3 1.5 1 0 0 1 1 1 0 FAM70 protein Fmp27_WPPW PF10359.4 EIE78839.1 - 0.54 8.6 13.5 0.022 13.2 2.2 2.3 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain Paf1 PF03985.8 EIE78839.1 - 4.1 6.0 35.9 0.51 9.0 13.4 2.9 3 0 0 3 3 3 0 Paf1 Prothymosin PF03247.9 EIE78839.1 - 5.5 7.1 68.1 2.9 8.0 7.7 3.6 3 0 0 3 3 3 0 Prothymosin/parathymosin family PIF1 PF05970.9 EIE78840.1 - 1.7e-24 86.4 0.2 7.8e-19 67.8 0.1 2.4 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 EIE78840.1 - 7.8e-15 54.9 0.0 1.3e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 EIE78840.1 - 2.8e-07 30.3 0.1 0.0003 20.4 0.0 2.3 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase Herpes_Helicase PF02689.9 EIE78840.1 - 3.9e-06 24.9 0.2 0.0029 15.4 0.0 2.4 2 1 1 3 3 3 2 Helicase AAA_19 PF13245.1 EIE78840.1 - 6.3e-06 25.8 0.0 1.5e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 EIE78840.1 - 1.8e-05 24.8 0.0 3.4e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EIE78840.1 - 0.00088 19.5 0.0 0.0015 18.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter Helicase_RecD PF05127.9 EIE78840.1 - 0.0032 17.1 0.2 0.053 13.1 0.1 2.2 1 1 0 1 1 1 1 Helicase AAA_17 PF13207.1 EIE78840.1 - 0.0034 18.1 0.1 0.012 16.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EIE78840.1 - 0.0041 17.0 0.0 0.012 15.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 EIE78840.1 - 0.0047 17.0 0.0 0.0098 16.0 0.0 1.5 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain KAP_NTPase PF07693.9 EIE78840.1 - 0.0078 15.2 0.0 0.0086 15.0 0.0 1.2 1 0 0 1 1 1 1 KAP family P-loop domain AAA_16 PF13191.1 EIE78840.1 - 0.019 14.9 0.0 0.037 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.7 EIE78840.1 - 0.021 14.4 0.0 0.061 12.9 0.0 1.7 2 0 0 2 2 2 0 NACHT domain PhoH PF02562.11 EIE78840.1 - 0.039 13.1 0.0 0.062 12.5 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_28 PF13521.1 EIE78840.1 - 0.052 13.5 0.1 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EIE78840.1 - 0.053 12.9 0.0 0.097 12.1 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF258 PF03193.11 EIE78840.1 - 0.065 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Sigma54_activ_2 PF14532.1 EIE78840.1 - 0.1 12.6 0.0 0.25 11.4 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain Helitron_like_N PF14214.1 EIE78841.1 - 5.4e-15 55.5 0.2 7.9e-15 55.0 0.1 1.2 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus DUF3296 PF11726.3 EIE78841.1 - 0.064 12.8 0.1 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3296) RPEL PF02755.10 EIE78841.1 - 0.092 12.1 0.0 0.23 10.8 0.0 1.7 1 0 0 1 1 1 0 RPEL repeat rve PF00665.21 EIE78842.1 - 1.2e-17 64.0 0.0 8.4e-17 61.3 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 EIE78842.1 - 5.7e-17 61.7 0.2 1.3e-16 60.5 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE78842.1 - 4.7e-09 35.7 0.5 1.2e-08 34.5 0.3 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.1 EIE78842.1 - 1.5e-07 31.7 0.1 4e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 EIE78842.1 - 1.1e-06 28.4 0.2 8.5e-06 25.6 0.1 2.6 2 0 0 2 2 2 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EIE78842.1 - 0.00078 19.2 0.0 0.0018 18.0 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.12 EIE78842.1 - 0.0014 18.6 2.4 0.0051 16.8 0.0 3.2 4 0 0 4 4 4 1 Retrotransposon gag protein Asp_protease PF09668.5 EIE78842.1 - 0.011 15.2 0.2 0.093 12.3 0.1 2.4 2 0 0 2 2 2 0 Aspartyl protease Tudor-knot PF11717.3 EIE78842.1 - 0.07 12.8 2.9 0.086 12.5 0.1 2.5 2 0 0 2 2 2 0 RNA binding activity-knot of a chromodomain IncA PF04156.9 EIE78842.1 - 1.4 8.4 6.5 3.6 7.1 4.5 1.6 1 0 0 1 1 1 0 IncA protein RVT_1 PF00078.22 EIE78845.1 - 7.4e-22 77.7 0.9 7.4e-22 77.7 0.6 2.3 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EIE78845.1 - 1.2e-19 70.6 0.0 2.9e-19 69.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.12 EIE78845.1 - 4.8e-18 65.0 1.5 2.1e-17 62.9 0.4 2.7 2 0 0 2 2 2 1 Retrotransposon gag protein Asp_protease_2 PF13650.1 EIE78845.1 - 4.4e-06 27.0 0.0 9.2e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EIE78845.1 - 2.5e-05 24.0 0.0 4.9e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 EIE78845.1 - 0.00012 21.8 0.0 0.00036 20.3 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.6 EIE78845.1 - 0.00069 19.5 0.0 0.0016 18.4 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 EIE78845.1 - 0.033 13.7 0.0 0.088 12.3 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC PF00098.18 EIE78845.1 - 0.073 13.0 0.6 0.17 11.8 0.4 1.7 1 0 0 1 1 1 0 Zinc knuckle Lzipper-MIP1 PF14389.1 EIE78846.1 - 0.0029 17.6 0.3 0.0088 16.1 0.2 1.8 1 0 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 DUF4404 PF14357.1 EIE78846.1 - 0.11 12.9 1.9 4 7.9 0.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) SRR PF07709.6 EIE78846.1 - 0.11 12.7 4.4 4.2 7.9 0.0 3.7 3 0 0 3 3 3 0 Seven Residue Repeat IncA PF04156.9 EIE78846.1 - 0.11 12.0 1.2 0.2 11.2 0.8 1.5 1 0 0 1 1 1 0 IncA protein DUF1002 PF06207.6 EIE78846.1 - 1.6 8.0 5.1 7.3 5.8 0.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1002) DUF972 PF06156.8 EIE78846.1 - 1.8 8.9 6.2 0.18 12.1 0.5 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF972) ChaB PF06150.7 EIE78846.1 - 3.1 7.6 6.6 0.25 11.1 0.4 2.3 2 1 1 3 3 3 0 ChaB DUF4218 PF13960.1 EIE78847.1 - 3.4e-05 23.3 0.0 6.4e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) DDE_3 PF13358.1 EIE78848.1 - 3.6e-12 46.2 0.2 4.7e-12 45.8 0.2 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE78849.1 - 6.4e-19 67.7 0.7 6.4e-19 67.7 0.5 2.9 3 1 1 4 4 4 1 Transposase DDE_3 PF13358.1 EIE78849.1 - 2.5e-08 33.7 1.0 2.4e-07 30.5 0.1 2.3 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_29 PF13551.1 EIE78849.1 - 1.7e-06 28.1 1.8 6.1e-06 26.3 0.9 2.1 2 1 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.1 EIE78849.1 - 2.5e-05 24.9 5.9 0.00058 20.5 0.2 3.8 3 1 1 4 4 4 1 Homeodomain-like domain HTH_23 PF13384.1 EIE78849.1 - 0.0009 18.8 0.8 0.061 13.0 0.0 3.4 3 0 0 3 3 3 1 Homeodomain-like domain HTH_21 PF13276.1 EIE78849.1 - 0.0096 15.9 0.3 0.62 10.1 0.0 2.9 2 1 1 3 3 3 1 HTH-like domain DUF3427 PF11907.3 EIE78849.1 - 0.072 12.0 0.3 0.12 11.2 0.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3427) Transposase_21 PF02992.9 EIE78850.1 - 1.5e-23 83.0 1.1 2.3e-23 82.4 0.1 1.7 2 0 0 2 2 2 1 Transposase family tnp2 DDE_Tnp_IS1595 PF12762.2 EIE78851.1 - 3.8e-21 75.5 0.0 5.4e-21 75.0 0.0 1.2 1 0 0 1 1 1 1 ISXO2-like transposase domain DDE_Tnp_IS66 PF03050.9 EIE78851.1 - 0.097 11.8 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Transposase IS66 family HTH_Tnp_Tc3_2 PF01498.13 EIE78852.1 - 6.8e-11 42.0 0.7 8.9e-11 41.7 0.5 1.2 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.1 EIE78853.1 - 4.3e-17 62.2 0.6 1.2e-16 60.7 0.1 2.0 3 0 0 3 3 3 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE78853.1 - 2.7e-10 40.1 0.3 6.5e-10 38.9 0.2 1.7 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.1 EIE78853.1 - 0.043 13.9 0.0 0.12 12.5 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn helix DDE_3 PF13358.1 EIE78855.1 - 3.2e-21 75.5 0.5 4.5e-21 75.1 0.3 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Flavi_capsid PF01003.14 EIE78856.1 - 0.026 14.0 0.0 0.04 13.4 0.0 1.4 1 0 0 1 1 1 0 Flavivirus capsid protein C Asp_protease_2 PF13650.1 EIE78857.1 - 0.0061 17.0 0.0 0.02 15.3 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EIE78857.1 - 0.042 13.6 0.0 0.09 12.6 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Chromo PF00385.19 EIE78858.1 - 0.0037 16.8 1.0 0.0099 15.5 0.1 2.2 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain FA_desaturase PF00487.19 EIE78859.1 - 7.6e-25 87.8 16.0 9.5e-25 87.4 11.1 1.1 1 0 0 1 1 1 1 Fatty acid desaturase DUF3185 PF11381.3 EIE78859.1 - 0.28 10.9 3.8 12 5.8 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF3185) WH2 PF02205.15 EIE78860.1 - 4e-09 35.7 1.8 1.3e-08 34.1 0.7 2.2 2 0 0 2 2 2 1 WH2 motif UPF0121 PF03661.8 EIE78861.1 - 2.5e-08 33.4 7.7 3.1e-08 33.1 5.3 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) Flavodoxin_4 PF12682.2 EIE78861.1 - 0.021 14.2 0.0 0.032 13.5 0.0 1.2 1 0 0 1 1 1 0 Flavodoxin DUF3671 PF12420.3 EIE78861.1 - 8.9 6.3 8.3 2 8.4 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function Ribosomal_L28e PF01778.12 EIE78863.1 - 1.5e-26 93.1 1.6 1.5e-26 93.1 1.1 2.1 1 1 1 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.9 EIE78863.1 - 1.4e-24 86.0 23.1 1.4e-24 86.0 16.0 1.6 2 0 0 2 2 2 1 Mak16 protein C-terminal region Cwf_Cwc_15 PF04889.7 EIE78863.1 - 0.38 10.4 15.6 0.5 10.0 10.8 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Peptidase_S46 PF10459.4 EIE78863.1 - 0.65 8.3 9.0 0.83 7.9 6.2 1.0 1 0 0 1 1 1 0 Peptidase S46 Pkinase PF00069.20 EIE78864.1 - 1.9e-51 174.7 0.0 2.7e-51 174.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE78864.1 - 8.1e-20 70.9 0.0 1.1e-19 70.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIE78864.1 - 0.00098 18.9 0.0 0.0091 15.7 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EIE78864.1 - 0.0019 17.1 0.0 0.0048 15.9 0.0 1.6 2 1 0 2 2 2 1 Kinase-like Mis14 PF08641.7 EIE78864.1 - 0.076 13.0 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Kinetochore protein Mis14 like DDE_3 PF13358.1 EIE78865.1 - 4.2e-16 58.9 0.0 8.3e-16 58.0 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE78865.1 - 5.3e-06 26.4 0.8 1.8e-05 24.6 0.8 1.8 2 0 0 2 2 2 1 Transposase NUDIX_4 PF14815.1 EIE78865.1 - 0.0078 15.6 0.3 0.013 14.9 0.2 1.4 1 0 0 1 1 1 1 NUDIX domain DDE_3 PF13358.1 EIE78866.1 - 4.7e-21 75.0 0.0 9.6e-21 74.0 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE78866.1 - 2e-15 56.5 2.2 5.3e-15 55.2 0.3 2.5 3 0 0 3 3 3 1 Transposase HTH_29 PF13551.1 EIE78866.1 - 2.2e-06 27.8 0.3 8.6e-06 25.8 0.2 2.0 2 0 0 2 2 2 1 Winged helix-turn helix HTH_38 PF13936.1 EIE78866.1 - 1.1e-05 24.8 0.1 3.3e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_32 PF13565.1 EIE78866.1 - 4.7e-05 24.1 2.7 0.02 15.6 0.1 3.8 4 0 0 4 4 3 1 Homeodomain-like domain HTH_23 PF13384.1 EIE78866.1 - 8e-05 22.1 0.1 0.0028 17.2 0.0 2.7 2 0 0 2 2 2 1 Homeodomain-like domain Sigma70_r4_2 PF08281.7 EIE78866.1 - 0.00051 19.4 1.0 0.024 14.0 0.0 3.3 4 0 0 4 4 4 1 Sigma-70, region 4 HTH_28 PF13518.1 EIE78866.1 - 0.0013 18.6 0.0 0.0056 16.6 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_21 PF13276.1 EIE78866.1 - 0.0016 18.3 0.2 0.13 12.2 0.0 2.8 3 0 0 3 3 2 1 HTH-like domain HTH_7 PF02796.10 EIE78866.1 - 0.0024 17.6 1.1 0.1 12.4 0.0 2.7 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase LacI PF00356.16 EIE78866.1 - 0.015 14.9 1.3 2.8 7.6 0.2 2.6 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family HTH_Tnp_4 PF13613.1 EIE78866.1 - 0.022 14.2 0.1 0.057 12.9 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease CPSase_L_D3 PF02787.14 EIE78866.1 - 0.059 13.1 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain HTH_36 PF13730.1 EIE78866.1 - 0.071 13.2 0.4 4.1 7.6 0.0 3.0 3 0 0 3 3 2 0 Helix-turn-helix domain HTH_17 PF12728.2 EIE78866.1 - 0.12 12.6 1.0 15 5.9 0.1 2.9 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.1 EIE78866.1 - 0.17 11.0 2.8 8.4 5.6 0.0 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 Lzipper-MIP1 PF14389.1 EIE78867.1 - 0.00093 19.2 0.5 0.0013 18.7 0.3 1.2 1 0 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 DUF2397 PF09660.5 EIE78867.1 - 0.0085 14.7 0.4 0.01 14.4 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2397) Cast PF10174.4 EIE78867.1 - 0.0095 14.0 4.0 0.012 13.7 2.8 1.0 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone ChaB PF06150.7 EIE78867.1 - 0.033 13.9 0.1 0.05 13.3 0.1 1.3 1 0 0 1 1 1 0 ChaB UPF0242 PF06785.6 EIE78867.1 - 0.036 12.7 2.3 0.044 12.4 1.6 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) Sec5 PF15469.1 EIE78867.1 - 0.049 13.3 0.6 0.073 12.7 0.4 1.2 1 0 0 1 1 1 0 Exocyst complex component Sec5 V_ATPase_I PF01496.14 EIE78867.1 - 0.093 10.5 1.9 0.11 10.3 1.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ERM PF00769.14 EIE78867.1 - 0.18 11.3 8.1 0.24 10.9 5.6 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF972 PF06156.8 EIE78867.1 - 0.33 11.3 3.4 0.36 11.1 2.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Adeno_PIX PF03955.9 EIE78867.1 - 1.7 9.1 4.0 51 4.4 2.8 2.1 1 1 0 1 1 1 0 Adenovirus hexon-associated protein (IX) DDE_3 PF13358.1 EIE78868.1 - 2.2e-19 69.6 0.0 4.2e-19 68.7 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE78868.1 - 4e-08 33.2 1.1 2.3e-07 30.7 0.9 2.2 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.1 EIE78868.1 - 0.00018 21.0 0.1 0.017 14.7 0.0 3.0 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.1 EIE78868.1 - 0.0048 16.8 0.0 2 8.4 0.0 2.8 2 0 0 2 2 2 2 Helix-turn-helix domain DUF1884 PF08967.5 EIE78869.1 - 0.017 15.1 0.0 0.027 14.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1884) rve PF00665.21 EIE78870.1 - 1.1e-16 60.9 0.0 4.8e-16 58.9 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE78870.1 - 6.3e-11 42.0 0.5 5.5e-10 38.9 0.2 2.6 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE78870.1 - 2.8e-08 33.3 2.9 9.9e-08 31.5 0.1 2.9 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain RVP PF00077.15 EIE78870.1 - 0.002 17.9 0.1 0.0088 15.9 0.1 2.2 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 EIE78870.1 - 0.0042 17.5 0.1 0.0092 16.4 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.12 EIE78870.1 - 0.033 14.2 0.0 0.26 11.4 0.0 2.6 1 0 0 1 1 1 0 Retrotransposon gag protein Mto2_bdg PF12808.2 EIE78874.1 - 0.29 11.2 7.4 1.4 9.0 0.3 3.3 3 0 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Transposase_21 PF02992.9 EIE78875.1 - 2.7e-21 75.7 0.1 2.7e-21 75.7 0.0 1.6 2 0 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.1 EIE78875.1 - 4.9e-05 22.7 0.3 0.0001 21.7 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) DDE_Tnp_IS1595 PF12762.2 EIE78878.1 - 7.4e-19 68.0 0.1 1.1e-18 67.5 0.0 1.2 1 0 0 1 1 1 1 ISXO2-like transposase domain HTH_Tnp_Tc3_2 PF01498.13 EIE78881.1 - 0.00023 21.1 0.3 0.00041 20.3 0.2 1.5 1 0 0 1 1 1 1 Transposase Galactosyl_T PF01762.16 EIE78881.1 - 0.078 12.5 0.1 0.09 12.3 0.1 1.1 1 0 0 1 1 1 0 Galactosyltransferase HTH_Tnp_Tc3_2 PF01498.13 EIE78883.1 - 3.5e-07 30.1 1.0 4.5e-07 29.8 0.7 1.2 1 0 0 1 1 1 1 Transposase SPOR PF05036.8 EIE78883.1 - 0.0097 16.0 0.0 0.023 14.8 0.0 1.6 1 1 1 2 2 2 1 Sporulation related domain Transposase_21 PF02992.9 EIE78884.1 - 1.9e-22 79.5 0.1 1.9e-22 79.5 0.1 1.7 2 0 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.1 EIE78884.1 - 3.4e-05 23.2 0.3 7.5e-05 22.1 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Leader_Erm PF08253.6 EIE78885.1 - 0.33 10.4 0.3 0.33 10.4 0.2 2.1 2 0 0 2 2 2 0 Erm Leader peptide DDE_3 PF13358.1 EIE78888.1 - 2.9e-12 46.5 0.1 3.8e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EIE78889.1 - 9.6e-24 83.7 0.0 1.2e-23 83.5 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE78889.1 - 0.00017 21.6 0.0 0.00031 20.8 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain HTH_32 PF13565.1 EIE78890.1 - 2.5e-05 24.9 0.0 3.6e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.1 EIE78890.1 - 0.028 14.5 0.0 0.034 14.3 0.0 1.1 1 0 0 1 1 1 0 Winged helix-turn helix Transposase_21 PF02992.9 EIE78893.1 - 6.3e-07 28.7 0.0 1.1e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 DUF3713 PF12506.3 EIE78893.1 - 9.3e-05 22.4 0.4 0.00018 21.5 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3713) TGS PF02824.16 EIE78893.1 - 0.0087 15.8 0.0 2.1 8.2 0.0 2.8 2 1 0 2 2 2 2 TGS domain DDE_3 PF13358.1 EIE78894.1 - 8.6e-16 58.0 0.0 1.8e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE78894.1 - 9e-09 35.2 1.3 4.3e-08 33.0 0.2 2.5 1 1 1 2 2 2 1 Transposase HTH_Tnp_Tc3_2 PF01498.13 EIE78897.1 - 6.3e-12 45.3 0.3 1.5e-11 44.1 0.2 1.7 1 0 0 1 1 1 1 Transposase Chal_sti_synt_C PF02797.10 EIE78897.1 - 0.15 11.9 0.6 1.1 9.1 0.0 2.3 3 0 0 3 3 3 0 Chalcone and stilbene synthases, C-terminal domain DDE_3 PF13358.1 EIE78898.1 - 6.1e-11 42.2 0.0 6.9e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-CCHC_4 PF14392.1 EIE78899.1 - 0.00011 21.8 2.8 0.024 14.2 0.0 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC PF00098.18 EIE78899.1 - 0.0016 18.2 12.6 0.13 12.2 2.5 2.5 2 0 0 2 2 2 2 Zinc knuckle RRM_5 PF13893.1 EIE78899.1 - 0.13 12.1 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DDE_3 PF13358.1 EIE78900.1 - 5.1e-35 120.3 0.1 2.5e-17 62.9 0.0 2.5 2 0 0 2 2 2 2 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE78900.1 - 3.8e-08 33.2 0.6 1.2e-07 31.6 0.4 2.0 1 1 0 1 1 1 1 Transposase NUDIX_4 PF14815.1 EIE78900.1 - 0.0051 16.2 4.2 0.19 11.1 0.1 2.3 2 0 0 2 2 2 2 NUDIX domain DUF4081 PF13312.1 EIE78900.1 - 0.099 12.5 0.5 5.6 6.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4081) HCBP_related PF06594.6 EIE78900.1 - 0.11 12.1 0.0 3 7.5 0.0 2.8 2 0 0 2 2 2 0 Haemolysin-type calcium binding protein related domain NDUF_B6 PF09782.4 EIE78900.1 - 0.3 10.9 7.2 1.2 8.9 0.4 2.8 2 1 0 2 2 2 0 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit HTH_Tnp_Tc3_2 PF01498.13 EIE78901.1 - 2.9e-08 33.6 0.1 6.1e-08 32.6 0.1 1.6 1 0 0 1 1 1 1 Transposase Transposase_21 PF02992.9 EIE78902.1 - 1.3e-13 50.5 0.0 1.4e-13 50.4 0.0 1.0 1 0 0 1 1 1 1 Transposase family tnp2 DUF1042 PF06294.6 EIE78902.1 - 0.1 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1042) DDE_3 PF13358.1 EIE78903.1 - 2.1e-14 53.4 0.0 2.8e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1010 PF06231.6 EIE78904.1 - 0.47 10.4 2.8 0.62 10.1 0.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1010) DivIC PF04977.10 EIE78906.1 - 0.00011 21.5 1.2 0.00014 21.2 0.9 1.1 1 0 0 1 1 1 1 Septum formation initiator DivIVA PF05103.8 EIE78906.1 - 0.001 19.0 1.1 0.0013 18.7 0.7 1.1 1 0 0 1 1 1 1 DivIVA protein bZIP_1 PF00170.16 EIE78906.1 - 0.0032 17.3 1.7 0.0044 16.9 1.2 1.2 1 0 0 1 1 1 1 bZIP transcription factor DUF972 PF06156.8 EIE78906.1 - 0.0054 17.0 0.5 0.0064 16.8 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF972) MAD PF05557.8 EIE78906.1 - 0.0058 14.7 0.4 0.0068 14.5 0.3 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein ADIP PF11559.3 EIE78906.1 - 0.0099 15.7 1.8 0.011 15.6 1.3 1.1 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding ATG16 PF08614.6 EIE78906.1 - 0.011 15.5 0.1 0.012 15.4 0.1 1.0 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) bZIP_2 PF07716.10 EIE78906.1 - 0.013 15.2 4.1 0.014 15.1 2.3 1.5 1 1 0 1 1 1 0 Basic region leucine zipper Ax_dynein_light PF10211.4 EIE78906.1 - 0.014 15.2 0.2 0.016 15.0 0.2 1.2 1 0 0 1 1 1 0 Axonemal dynein light chain BCAS2 PF05700.6 EIE78906.1 - 0.017 14.6 0.3 0.019 14.4 0.2 1.1 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) Herpes_UL6 PF01763.11 EIE78906.1 - 0.025 12.7 0.2 0.029 12.5 0.1 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like DASH_Spc34 PF08657.5 EIE78906.1 - 0.027 14.1 0.3 0.032 13.9 0.2 1.1 1 0 0 1 1 1 0 DASH complex subunit Spc34 TMF_DNA_bd PF12329.3 EIE78906.1 - 0.028 14.2 4.0 0.041 13.6 2.8 1.1 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding IncA PF04156.9 EIE78906.1 - 0.035 13.6 0.3 0.038 13.5 0.2 1.0 1 0 0 1 1 1 0 IncA protein Shugoshin_N PF07558.6 EIE78906.1 - 0.048 13.3 1.5 0.11 12.1 0.7 1.8 1 1 1 2 2 2 0 Shugoshin N-terminal coiled-coil region DUF4140 PF13600.1 EIE78906.1 - 0.048 14.1 0.2 0.055 13.9 0.2 1.1 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF4446 PF14584.1 EIE78906.1 - 0.049 13.4 0.2 0.051 13.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) BLOC1_2 PF10046.4 EIE78906.1 - 0.067 13.3 1.1 0.091 12.9 0.8 1.1 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NEMO PF11577.3 EIE78906.1 - 0.081 12.6 1.4 0.11 12.2 0.9 1.2 1 0 0 1 1 1 0 NF-kappa-B essential modulator NEMO MbeD_MobD PF04899.7 EIE78906.1 - 0.11 12.4 0.9 0.15 12.0 0.6 1.2 1 0 0 1 1 1 0 MbeD/MobD like XhlA PF10779.4 EIE78906.1 - 0.17 11.8 3.4 0.22 11.4 2.3 1.1 1 0 0 1 1 1 0 Haemolysin XhlA DUF904 PF06005.7 EIE78906.1 - 0.32 11.2 3.6 0.44 10.8 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DUF2630 PF10944.3 EIE78906.1 - 0.46 10.6 2.3 0.66 10.1 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2630) DDE_3 PF13358.1 EIE78907.1 - 5.4e-08 32.6 0.5 5.4e-08 32.6 0.4 1.8 2 1 0 2 2 2 1 DDE superfamily endonuclease NUDIX_4 PF14815.1 EIE78907.1 - 0.0084 15.5 0.3 0.012 15.0 0.2 1.3 1 0 0 1 1 1 1 NUDIX domain Imm35 PF15581.1 EIE78907.1 - 0.045 13.7 0.2 0.12 12.3 0.0 1.8 2 0 0 2 2 2 0 Immunity protein 35 INCA1 PF15142.1 EIE78907.1 - 0.093 12.5 0.2 0.38 10.5 0.0 1.9 2 1 1 3 3 3 0 INCA1 HTH_Tnp_Tc3_2 PF01498.13 EIE78908.1 - 2.7e-07 30.5 0.6 5e-07 29.6 0.4 1.5 1 0 0 1 1 1 1 Transposase HTH_Tnp_Tc3_2 PF01498.13 EIE78910.1 - 2.5e-16 59.5 2.0 8.2e-16 57.8 0.3 2.2 2 1 1 3 3 3 1 Transposase HTH_32 PF13565.1 EIE78910.1 - 8.8e-06 26.4 1.1 0.0075 17.0 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_38 PF13936.1 EIE78910.1 - 1.2e-05 24.7 0.0 4.7e-05 22.8 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_29 PF13551.1 EIE78910.1 - 1.3e-05 25.3 1.8 1.3e-05 25.2 0.2 1.8 2 1 0 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.1 EIE78910.1 - 8.2e-05 22.1 0.0 0.0059 16.2 0.0 2.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_7 PF02796.10 EIE78910.1 - 8.2e-05 22.3 0.5 0.016 15.0 0.0 2.9 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase Sigma70_r4_2 PF08281.7 EIE78910.1 - 0.0005 19.4 0.4 0.019 14.3 0.0 2.7 3 0 0 3 3 3 1 Sigma-70, region 4 HTH_21 PF13276.1 EIE78910.1 - 0.0011 18.9 0.0 0.05 13.6 0.0 2.3 2 0 0 2 2 2 1 HTH-like domain Sigma70_r4 PF04545.11 EIE78910.1 - 0.0036 16.5 0.1 0.031 13.5 0.0 2.4 3 0 0 3 3 3 1 Sigma-70, region 4 HTH_28 PF13518.1 EIE78910.1 - 0.008 16.1 0.0 0.05 13.6 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.1 EIE78910.1 - 0.013 14.6 2.5 1.8 7.8 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 LacI PF00356.16 EIE78910.1 - 0.017 14.7 0.7 1.1 8.9 0.2 2.4 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family HTH_Tnp_4 PF13613.1 EIE78910.1 - 0.024 14.1 0.5 0.045 13.2 0.1 1.6 2 0 0 2 2 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_17 PF12728.2 EIE78910.1 - 0.049 13.8 0.4 10 6.4 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain GerE PF00196.14 EIE78910.1 - 0.049 12.9 0.0 1.7 8.0 0.0 2.4 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family HTH_40 PF14493.1 EIE78910.1 - 0.065 13.4 0.0 0.15 12.2 0.0 1.7 1 1 0 1 1 1 0 Helix-turn-helix domain UPF0122 PF04297.9 EIE78910.1 - 0.13 12.2 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like DDE_3 PF13358.1 EIE78911.1 - 7.5e-10 38.7 0.0 7.7e-10 38.6 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EIE78912.1 - 3.6e-19 68.9 0.3 1.2e-17 64.0 0.1 3.0 3 0 0 3 3 3 1 DDE superfamily endonuclease GCR1_C PF12550.3 EIE78912.1 - 3.7e-14 52.3 0.8 3.7e-14 52.3 0.6 2.4 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes HTH_Tnp_Tc3_2 PF01498.13 EIE78912.1 - 3.1e-10 39.9 0.3 7.3e-10 38.7 0.2 1.7 1 0 0 1 1 1 1 Transposase KxDL PF10241.4 EIE78913.1 - 0.045 13.6 0.0 0.068 13.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein RVT_1 PF00078.22 EIE78914.1 - 3.6e-15 55.8 0.0 7.5e-15 54.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.5 EIE78914.1 - 0.00028 20.2 0.1 0.00073 18.8 0.1 1.8 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger UBN2_2 PF14227.1 EIE78914.1 - 0.0024 17.4 0.1 0.089 12.3 0.0 2.5 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EIE78914.1 - 0.04 13.6 0.2 0.14 11.9 0.0 2.0 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type HTH_Tnp_Tc3_2 PF01498.13 EIE78915.1 - 5.4e-10 39.1 0.1 9e-10 38.4 0.1 1.4 1 0 0 1 1 1 1 Transposase DDE_Tnp_ISAZ013 PF07592.6 EIE78915.1 - 0.035 12.8 0.0 0.045 12.5 0.0 1.1 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain NUC153 PF08159.7 EIE78916.1 - 0.023 14.2 0.1 0.047 13.2 0.1 1.5 1 0 0 1 1 1 0 NUC153 domain Transposase_21 PF02992.9 EIE78917.1 - 9.9e-16 57.5 0.1 9.6e-15 54.2 0.0 2.3 1 1 1 2 2 2 1 Transposase family tnp2 DivIC PF04977.10 EIE78918.1 - 0.0006 19.2 1.2 0.0016 17.9 0.9 1.7 1 0 0 1 1 1 1 Septum formation initiator DivIVA PF05103.8 EIE78918.1 - 0.0011 19.0 0.7 0.0011 19.0 0.5 1.9 2 0 0 2 2 2 1 DivIVA protein ADIP PF11559.3 EIE78918.1 - 0.035 13.9 0.6 0.035 13.9 0.4 1.9 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding bZIP_1 PF00170.16 EIE78918.1 - 0.042 13.8 1.7 0.042 13.8 1.2 2.2 3 0 0 3 3 3 0 bZIP transcription factor DUF972 PF06156.8 EIE78918.1 - 0.043 14.1 0.4 0.043 14.1 0.3 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF972) BLOC1_2 PF10046.4 EIE78918.1 - 0.057 13.5 1.1 0.6 10.2 0.6 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 IncA PF04156.9 EIE78918.1 - 0.65 9.5 3.4 0.42 10.1 0.1 2.2 3 0 0 3 3 3 0 IncA protein XhlA PF10779.4 EIE78918.1 - 0.8 9.6 5.0 0.4 10.6 1.6 1.9 2 0 0 2 2 2 0 Haemolysin XhlA DUF4200 PF13863.1 EIE78918.1 - 0.92 9.4 11.9 1.4 8.8 1.2 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) DDE_3 PF13358.1 EIE78919.1 - 1.1e-15 57.6 0.0 1.9e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE78919.1 - 5.7e-12 45.5 0.5 2e-11 43.7 0.3 2.0 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.1 EIE78919.1 - 0.00096 19.2 0.6 0.0023 18.0 0.4 1.7 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EIE78919.1 - 0.001 18.6 0.0 0.0026 17.3 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_7 PF02796.10 EIE78919.1 - 0.0015 18.3 0.5 0.07 12.9 0.1 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase DDE_3 PF13358.1 EIE78921.1 - 2e-14 53.5 0.2 2.9e-14 53.0 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Cas_Csx9 PF09658.5 EIE78921.1 - 0.07 11.9 0.0 0.1 11.3 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csx9) DDE_3 PF13358.1 EIE78924.1 - 5.5e-21 74.8 0.0 1.8e-20 73.1 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease PHD_2 PF13831.1 EIE78924.1 - 0.074 12.3 0.7 0.22 10.8 0.5 1.8 1 0 0 1 1 1 0 PHD-finger Peptidase_C37 PF05416.7 EIE78925.1 - 0.88 7.7 6.1 0.35 9.0 0.5 2.0 2 0 0 2 2 2 0 Southampton virus-type processing peptidase NARG2_C PF10505.4 EIE78926.1 - 0.0013 17.9 0.0 0.0016 17.6 0.0 1.2 1 0 0 1 1 1 1 NMDA receptor-regulated gene protein 2 C-terminus U-box PF04564.10 EIE78927.1 - 8.8e-10 38.4 0.0 2e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 U-box domain zf-C3HC4_2 PF13923.1 EIE78927.1 - 1.6e-08 34.4 13.4 1.6e-08 34.4 9.3 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-CCHC PF00098.18 EIE78927.1 - 6.3e-05 22.7 2.9 6.3e-05 22.7 2.0 2.5 2 0 0 2 2 2 1 Zinc knuckle zf-RING_2 PF13639.1 EIE78927.1 - 7.4e-05 22.5 14.0 0.00015 21.5 9.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-CCHC_3 PF13917.1 EIE78927.1 - 0.00042 20.0 2.6 0.00042 20.0 1.8 1.9 2 0 0 2 2 2 1 Zinc knuckle zf-RING_6 PF14835.1 EIE78927.1 - 0.0019 17.9 6.3 0.0035 17.0 4.4 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_3 PF13920.1 EIE78927.1 - 0.0033 17.0 14.4 0.0033 17.0 9.9 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIE78927.1 - 0.0062 16.2 16.7 0.0062 16.2 11.5 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EIE78927.1 - 0.018 14.7 14.0 0.04 13.5 9.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EIE78927.1 - 0.45 10.6 9.0 1 9.5 6.2 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger zf-CCHC_2 PF13696.1 EIE78927.1 - 0.51 9.8 9.9 0.028 13.9 2.7 2.0 2 0 0 2 2 2 0 Zinc knuckle zf-C3HC4_4 PF15227.1 EIE78927.1 - 3 7.8 17.1 0.27 11.1 8.4 1.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Prion PF00377.13 EIE78927.1 - 7.1 6.3 8.1 5.1 6.8 3.1 2.3 1 1 1 2 2 2 0 Prion/Doppel alpha-helical domain AAA PF00004.24 EIE78928.1 - 1.6e-42 144.8 0.0 3e-42 143.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EIE78928.1 - 6.5e-30 102.8 1.4 9.4e-29 99.0 0.1 2.8 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain AAA_17 PF13207.1 EIE78928.1 - 9e-06 26.5 0.2 3.5e-05 24.6 0.0 2.1 2 1 0 2 2 1 1 AAA domain AAA_22 PF13401.1 EIE78928.1 - 1.3e-05 25.3 0.1 0.0013 18.8 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EIE78928.1 - 1.6e-05 24.6 0.0 9.2e-05 22.1 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 EIE78928.1 - 2.9e-05 23.5 0.0 5e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 EIE78928.1 - 3.1e-05 23.8 0.0 0.00012 21.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EIE78928.1 - 3.6e-05 22.9 0.0 7.2e-05 21.9 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus RNA_helicase PF00910.17 EIE78928.1 - 7e-05 22.9 0.3 0.0082 16.3 0.0 3.3 3 0 0 3 3 3 1 RNA helicase AAA_16 PF13191.1 EIE78928.1 - 9.1e-05 22.5 0.0 0.00037 20.5 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain MIT PF04212.13 EIE78928.1 - 0.00015 21.6 0.4 0.0013 18.6 0.0 2.7 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain AAA_25 PF13481.1 EIE78928.1 - 0.00043 19.7 0.1 0.19 11.1 0.1 2.4 1 1 1 2 2 2 1 AAA domain TIP49 PF06068.8 EIE78928.1 - 0.00045 19.0 0.0 0.00071 18.4 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus DUF815 PF05673.8 EIE78928.1 - 0.00046 19.1 0.0 0.001 18.0 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 EIE78928.1 - 0.0008 19.2 0.0 0.0018 18.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EIE78928.1 - 0.0015 18.4 0.0 0.0048 16.8 0.0 1.9 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 EIE78928.1 - 0.0044 17.3 0.0 0.014 15.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 EIE78928.1 - 0.0088 15.8 0.1 0.097 12.5 0.0 2.2 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit Zeta_toxin PF06414.7 EIE78928.1 - 0.011 14.8 0.1 0.18 10.8 0.0 2.4 1 1 1 2 2 2 0 Zeta toxin Arch_ATPase PF01637.13 EIE78928.1 - 0.012 15.2 0.3 0.37 10.4 0.0 2.7 2 1 1 3 3 3 0 Archaeal ATPase AAA_24 PF13479.1 EIE78928.1 - 0.014 14.9 0.0 0.03 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EIE78928.1 - 0.022 14.5 0.0 0.05 13.3 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Mg_chelatase PF01078.16 EIE78928.1 - 0.026 13.6 0.0 0.06 12.5 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Parvo_NS1 PF01057.12 EIE78928.1 - 0.038 12.8 0.0 0.068 12.0 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Torsin PF06309.6 EIE78928.1 - 0.039 13.8 0.0 0.071 12.9 0.0 1.4 1 0 0 1 1 1 0 Torsin PhoH PF02562.11 EIE78928.1 - 0.047 12.9 0.0 0.093 11.9 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.7 EIE78928.1 - 0.051 13.2 0.0 0.41 10.2 0.0 2.1 1 1 1 2 2 2 0 NACHT domain KaiC PF06745.8 EIE78928.1 - 0.054 12.5 0.1 5.6 5.9 0.0 2.6 2 1 1 3 3 3 0 KaiC AAA_28 PF13521.1 EIE78928.1 - 0.12 12.2 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 EIE78928.1 - 0.12 12.3 0.0 0.36 10.8 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_21 PF13304.1 EIE78928.1 - 0.16 11.8 0.1 2.7 7.8 0.0 2.2 1 1 0 2 2 2 0 AAA domain E1-E2_ATPase PF00122.15 EIE78929.1 - 2.2e-58 197.0 2.1 2.2e-58 197.0 1.5 2.5 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 EIE78929.1 - 4.2e-20 73.0 0.0 2.5e-19 70.5 0.0 2.6 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EIE78929.1 - 1.1e-14 53.6 0.0 2.7e-14 52.3 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EIE78929.1 - 2.4e-12 47.4 0.0 5e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EIE78929.1 - 2.5e-05 23.9 0.3 4.9e-05 23.0 0.2 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EIE78929.1 - 0.099 12.6 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit GATA PF00320.22 EIE78930.1 - 1e-15 56.7 5.2 1.8e-15 56.0 3.6 1.4 1 0 0 1 1 1 1 GATA zinc finger NMD3 PF04981.8 EIE78930.1 - 0.057 12.5 1.9 0.097 11.7 1.3 1.3 1 1 0 1 1 1 0 NMD3 family PTEN_C2 PF10409.4 EIE78932.1 - 2.8e-07 30.3 1.3 4.6e-07 29.6 0.9 1.4 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein Y_phosphatase3 PF13350.1 EIE78932.1 - 3.5e-07 30.6 0.0 6.5e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 EIE78932.1 - 5.4e-07 29.2 0.0 7.5e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 EIE78932.1 - 2.9e-06 26.8 0.0 5.8e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 EIE78932.1 - 7.8e-05 22.7 0.0 0.00016 21.7 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase2 PF03162.8 EIE78932.1 - 0.00047 19.5 1.2 0.0013 18.1 0.4 1.8 1 1 1 2 2 2 1 Tyrosine phosphatase family CDKN3 PF05706.7 EIE78932.1 - 0.00073 19.0 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Usp PF00582.21 EIE78933.1 - 0.012 15.7 0.1 0.063 13.4 0.0 2.0 2 0 0 2 2 2 0 Universal stress protein family DUF4552 PF15089.1 EIE78933.1 - 0.03 13.2 0.3 0.052 12.4 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4552) PCI PF01399.22 EIE78934.1 - 0.00013 22.2 0.5 0.0004 20.6 0.4 1.8 1 0 0 1 1 1 1 PCI domain CRAL_TRIO_2 PF13716.1 EIE78934.1 - 0.042 13.7 0.0 0.11 12.4 0.0 1.8 1 1 0 1 1 1 0 Divergent CRAL/TRIO domain DUF445 PF04286.7 EIE78934.1 - 0.065 12.7 0.1 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF445) 60KD_IMP PF02096.15 EIE78935.1 - 4.2e-18 65.7 0.1 6e-18 65.2 0.1 1.1 1 0 0 1 1 1 1 60Kd inner membrane protein GPDPase_memb PF10110.4 EIE78935.1 - 0.25 10.7 2.9 0.22 10.9 0.3 1.9 2 0 0 2 2 2 0 Membrane domain of glycerophosphoryl diester phosphodiesterase Ribosomal_L38e PF01781.13 EIE78936.1 - 1.3e-34 117.7 4.1 1.4e-34 117.6 2.9 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family TFIID_90kDa PF04494.10 EIE78936.1 - 0.0097 15.9 0.2 0.01 15.8 0.1 1.1 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit Arena_RNA_pol PF06317.6 EIE78939.1 - 0.07 9.7 0.0 0.07 9.7 0.0 1.0 1 0 0 1 1 1 0 Arenavirus RNA polymerase 6PF2K PF01591.13 EIE78939.1 - 0.082 11.9 0.2 0.082 11.9 0.1 1.0 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Spc7 PF08317.6 EIE78940.1 - 0.0016 17.1 0.5 0.002 16.8 0.4 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein Cob_adeno_trans PF01923.13 EIE78940.1 - 0.0017 18.1 0.3 0.0024 17.7 0.2 1.3 1 0 0 1 1 1 1 Cobalamin adenosyltransferase DUF4201 PF13870.1 EIE78940.1 - 0.006 16.0 4.1 0.011 15.2 2.8 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4201) Vinculin PF01044.14 EIE78940.1 - 0.011 13.7 0.6 0.013 13.5 0.4 1.0 1 0 0 1 1 1 0 Vinculin family ERM PF00769.14 EIE78940.1 - 0.017 14.6 1.1 0.021 14.3 0.8 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Mnd1 PF03962.10 EIE78940.1 - 0.037 13.6 1.1 0.049 13.2 0.8 1.1 1 0 0 1 1 1 0 Mnd1 family WEMBL PF05701.6 EIE78940.1 - 0.038 12.4 2.2 0.049 12.0 1.5 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Tropomyosin PF00261.15 EIE78940.1 - 0.058 12.4 3.6 0.15 11.0 2.5 1.6 1 1 0 1 1 1 0 Tropomyosin TPD52 PF04201.10 EIE78940.1 - 0.072 12.8 1.8 0.096 12.4 1.1 1.3 1 1 0 1 1 1 0 Tumour protein D52 family Syntaxin-6_N PF09177.6 EIE78940.1 - 0.08 13.3 2.4 4.9 7.6 0.2 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Striatin PF08232.7 EIE78940.1 - 0.081 13.2 0.7 0.11 12.8 0.5 1.1 1 0 0 1 1 1 0 Striatin family IncA PF04156.9 EIE78940.1 - 0.1 12.1 3.8 0.17 11.4 2.6 1.4 1 1 0 1 1 1 0 IncA protein FlxA PF14282.1 EIE78940.1 - 0.11 12.4 2.0 0.28 11.1 1.4 1.6 1 1 0 1 1 1 0 FlxA-like protein Tropomyosin_1 PF12718.2 EIE78940.1 - 0.14 11.9 5.4 0.54 10.0 3.8 1.8 1 1 0 1 1 1 0 Tropomyosin like DUF2408 PF10303.4 EIE78940.1 - 0.24 11.4 2.6 0.45 10.6 0.9 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) Prefoldin_2 PF01920.15 EIE78940.1 - 0.65 9.7 5.8 2.4 7.9 1.1 2.2 1 1 1 2 2 2 0 Prefoldin subunit RNase_PH PF01138.16 EIE78941.1 - 6.7e-25 87.9 0.0 1.5e-24 86.7 0.0 1.6 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EIE78941.1 - 1.7e-11 43.8 0.1 3.6e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Ribosomal_S16 PF00886.14 EIE78941.1 - 0.018 14.7 0.0 0.036 13.7 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S16 La PF05383.12 EIE78942.1 - 4e-21 74.5 0.4 9.3e-21 73.3 0.2 1.7 1 0 0 1 1 1 1 La domain Scm3 PF10384.4 EIE78942.1 - 0.41 10.1 4.4 0.8 9.2 1.8 2.4 2 0 0 2 2 2 0 Centromere protein Scm3 ATP-synt_J PF04911.7 EIE78943.1 - 1.3e-19 69.3 0.3 1.4e-19 69.2 0.2 1.0 1 0 0 1 1 1 1 ATP synthase j chain bZIP_1 PF00170.16 EIE78945.1 - 5e-10 39.1 12.9 5e-10 39.1 8.9 2.5 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EIE78945.1 - 3.6e-06 26.6 13.4 3.6e-06 26.6 9.3 2.7 3 1 0 3 3 3 1 Basic region leucine zipper bZIP_Maf PF03131.12 EIE78945.1 - 0.00043 20.5 10.7 0.00043 20.5 7.4 2.4 2 0 0 2 2 2 1 bZIP Maf transcription factor CCDC92 PF14916.1 EIE78945.1 - 0.012 15.1 2.8 0.045 13.3 1.9 1.9 1 0 0 1 1 1 0 Coiled-coil domain of unknown function P4Ha_N PF08336.6 EIE78945.1 - 0.026 14.3 8.8 0.18 11.6 0.6 3.7 3 1 0 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region D123 PF07065.9 EIE78946.1 - 0.0056 15.7 0.1 0.0056 15.7 0.1 1.0 1 0 0 1 1 1 1 D123 Ribosomal_S25 PF03297.10 EIE78948.1 - 7.5e-42 141.6 3.3 9.1e-42 141.3 2.3 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_24 PF13412.1 EIE78948.1 - 0.0072 15.6 0.5 0.011 15.0 0.3 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding BioT2 PF15368.1 EIE78948.1 - 0.025 14.3 0.3 0.03 14.0 0.2 1.2 1 0 0 1 1 1 0 Spermatogenesis family BioT2 MarR_2 PF12802.2 EIE78948.1 - 0.049 13.3 0.0 0.065 12.9 0.0 1.2 1 0 0 1 1 1 0 MarR family BK_channel_a PF03493.13 EIE78949.1 - 4.9e-11 42.4 0.1 1.2e-10 41.1 0.0 1.7 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.11 EIE78949.1 - 5.5e-06 26.0 3.0 1.3e-05 24.8 2.1 1.5 1 0 0 1 1 1 1 Ion channel TrkA_N PF02254.13 EIE78949.1 - 0.00037 20.4 0.0 0.66 9.9 0.0 2.4 2 0 0 2 2 2 2 TrkA-N domain GDA1_CD39 PF01150.12 EIE78950.1 - 1.6e-88 297.0 0.0 3.2e-88 296.1 0.0 1.4 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Metallophos PF00149.23 EIE78950.1 - 2.8e-06 26.8 2.2 5.4e-06 25.9 1.6 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase 5_nucleotid_C PF02872.13 EIE78950.1 - 0.00012 22.1 0.0 0.00095 19.1 0.0 2.2 2 0 0 2 2 2 1 5'-nucleotidase, C-terminal domain Ppx-GppA PF02541.11 EIE78950.1 - 0.011 14.9 0.0 0.019 14.2 0.0 1.2 1 0 0 1 1 1 0 Ppx/GppA phosphatase family B12-binding PF02310.14 EIE78950.1 - 0.029 14.2 0.0 0.069 13.0 0.0 1.7 1 0 0 1 1 1 0 B12 binding domain UBA PF00627.26 EIE78951.1 - 1.2e-07 31.3 0.1 4.6e-07 29.4 0.0 2.0 2 0 0 2 2 2 1 UBA/TS-N domain DUF3173 PF11372.3 EIE78951.1 - 0.071 12.7 0.0 0.18 11.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3173) C2 PF00168.25 EIE78952.1 - 1.9e-82 271.1 15.4 1.6e-20 72.7 0.1 5.6 5 0 0 5 5 5 5 C2 domain DUF2404 PF10296.4 EIE78952.1 - 0.049 13.7 0.0 0.26 11.4 0.0 2.4 1 0 0 1 1 1 0 Putative integral membrane protein conserved region (DUF2404) SWIM PF04434.12 EIE78953.1 - 0.0057 16.1 0.8 0.011 15.1 0.5 1.4 1 0 0 1 1 1 1 SWIM zinc finger Pepsin-I3 PF06394.8 EIE78953.1 - 0.052 13.2 0.1 0.084 12.5 0.1 1.3 1 0 0 1 1 1 0 Pepsin inhibitor-3-like repeated domain Kinetochor_Ybp2 PF08568.5 EIE78954.1 - 0.083 11.1 0.1 0.098 10.8 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family, YAP/Alf4/glomulin Phytoreo_P8 PF07124.6 EIE78954.1 - 0.084 11.5 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 Phytoreovirus outer capsid protein P8 RRM_1 PF00076.17 EIE78956.1 - 5.2e-21 74.0 0.1 2e-20 72.1 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE78956.1 - 1.4e-13 50.6 0.0 1.9e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE78956.1 - 2.7e-05 23.9 0.0 4.1e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3543 PF12063.3 EIE78957.1 - 1.5e-53 181.4 7.7 2.3e-51 174.3 4.6 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF3543) Pkinase PF00069.20 EIE78957.1 - 2.4e-45 154.7 0.0 5.6e-45 153.5 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE78957.1 - 6.3e-29 100.8 0.0 1.2e-28 99.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIE78957.1 - 0.0023 17.7 0.1 0.0064 16.2 0.1 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EIE78957.1 - 0.0038 16.2 0.0 1.1 8.1 0.0 2.3 2 0 0 2 2 2 2 Kinase-like MIT PF04212.13 EIE78957.1 - 0.0072 16.1 1.0 0.22 11.4 0.1 3.2 2 1 0 2 2 2 1 MIT (microtubule interacting and transport) domain DUF2802 PF10975.3 EIE78957.1 - 0.046 13.4 0.2 5.8 6.7 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) Pox_ser-thr_kin PF05445.6 EIE78957.1 - 2.8 6.6 6.5 0.58 8.8 0.1 2.3 3 0 0 3 3 3 0 Poxvirus serine/threonine protein kinase Zn_clus PF00172.13 EIE78958.1 - 0.0015 18.4 16.0 0.0025 17.6 11.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NPBW PF15180.1 EIE78958.1 - 0.044 13.4 0.1 0.14 11.8 0.1 1.8 1 0 0 1 1 1 0 Neuropeptides B and W Pkinase PF00069.20 EIE78959.1 - 1.5e-52 178.2 0.0 1.8e-52 178.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE78959.1 - 2.5e-27 95.6 0.0 3.2e-27 95.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE78959.1 - 0.047 12.6 0.0 0.081 11.8 0.0 1.4 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 EIE78959.1 - 0.057 13.1 0.0 0.93 9.1 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family ATP-synt_ab PF00006.20 EIE78960.1 - 5.8e-114 378.9 0.0 8.8e-114 378.3 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EIE78960.1 - 4.6e-25 88.2 0.1 7.6e-25 87.5 0.1 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EIE78960.1 - 2.5e-08 33.9 2.4 6.5e-08 32.6 0.3 2.6 3 0 0 3 3 3 1 ATP synthase alpha/beta family, beta-barrel domain AAA_14 PF13173.1 EIE78960.1 - 0.11 12.3 0.0 0.28 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain UQ_con PF00179.21 EIE78961.1 - 1.2e-14 53.9 4.4 4.9e-07 29.2 0.0 2.1 1 1 1 2 2 2 2 Ubiquitin-conjugating enzyme LRR_4 PF12799.2 EIE78962.1 - 5.7e-05 22.6 0.1 0.48 10.1 0.0 4.4 3 1 1 4 4 4 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EIE78962.1 - 0.00012 21.6 2.0 0.25 11.1 0.0 3.5 3 0 0 3 3 3 2 Leucine rich repeat LRR_7 PF13504.1 EIE78962.1 - 0.027 14.5 2.0 59 4.5 0.0 4.4 4 0 0 4 4 4 0 Leucine rich repeat LRR_1 PF00560.28 EIE78962.1 - 0.063 13.3 3.3 69 4.0 0.1 4.0 3 1 0 3 3 3 0 Leucine Rich Repeat LRR_6 PF13516.1 EIE78962.1 - 0.61 10.3 6.2 69 3.9 0.7 4.2 5 0 0 5 5 5 0 Leucine Rich repeat RRM_1 PF00076.17 EIE78963.1 - 2.4e-15 55.8 0.0 1e-11 44.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE78963.1 - 0.00023 21.0 0.1 0.002 18.0 0.0 2.5 3 1 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE78963.1 - 0.0022 17.7 0.0 0.18 11.6 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.20 EIE78964.1 - 4.4e-18 65.3 0.1 6.4e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE78964.1 - 9.2e-18 64.2 0.2 1.4e-17 63.6 0.1 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase SAP PF02037.22 EIE78964.1 - 0.0048 16.3 0.0 0.011 15.1 0.0 1.6 1 0 0 1 1 1 1 SAP domain Myb_DNA-bind_6 PF13921.1 EIE78965.1 - 2.5e-12 46.7 0.0 2.3e-08 34.0 0.0 3.6 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EIE78965.1 - 2e-10 40.5 0.1 0.00017 21.5 0.0 2.8 3 0 0 3 3 3 2 Myb-like DNA-binding domain Rap1_C PF11626.3 EIE78965.1 - 0.0023 17.7 0.0 0.008 16.0 0.0 2.0 1 0 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Bromodomain PF00439.20 EIE78966.1 - 4e-25 87.5 0.1 9.3e-25 86.3 0.1 1.7 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 EIE78966.1 - 9.2e-09 35.3 0.2 1.7e-08 34.4 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EIE78966.1 - 7.4e-08 32.3 0.1 2.4e-07 30.6 0.0 1.9 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 EIE78966.1 - 0.053 13.6 0.1 0.16 12.1 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain PAC2 PF09754.4 EIE78967.1 - 1.6e-23 83.7 0.0 3e-23 82.8 0.0 1.6 1 1 0 1 1 1 1 PAC2 family SNF2_N PF00176.18 EIE78967.1 - 0.089 11.5 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 SNF2 family N-terminal domain Homeobox PF00046.24 EIE78968.1 - 1.4e-16 59.8 1.7 2.3e-16 59.1 1.2 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EIE78968.1 - 0.00052 19.6 0.2 0.014 15.1 0.0 2.4 2 0 0 2 2 2 1 Homeobox KN domain HTH_23 PF13384.1 EIE78968.1 - 0.0012 18.3 0.4 0.018 14.6 0.0 2.3 1 1 1 2 2 2 1 Homeodomain-like domain GerE PF00196.14 EIE78968.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family Bromodomain PF00439.20 EIE78969.1 - 1.1e-47 159.8 3.2 2.4e-23 81.8 0.1 2.5 2 0 0 2 2 2 2 Bromodomain BLVR PF06375.6 EIE78969.1 - 0.0058 16.4 2.7 0.0058 16.4 1.8 2.3 1 1 0 2 2 2 1 Bovine leukaemia virus receptor (BLVR) STAT6_C PF14596.1 EIE78969.1 - 0.042 13.7 0.1 0.13 12.2 0.1 1.7 2 0 0 2 2 2 0 STAT6 C-terminal DUF755 PF05501.6 EIE78969.1 - 6.3 6.8 25.9 6.4 6.8 5.5 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF755) WD40 PF00400.27 EIE78970.1 - 4.6e-20 70.6 14.4 4.9e-09 35.7 0.2 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EIE78970.1 - 2.7e-13 49.5 0.0 6.7e-13 48.3 0.0 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex eIF2A PF08662.6 EIE78970.1 - 4.4e-05 23.2 0.2 0.00025 20.8 0.1 1.9 1 1 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A Lactonase PF10282.4 EIE78970.1 - 0.078 12.0 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller DnaJ-X PF14308.1 EIE78971.1 - 5.2e-53 179.3 1.2 5.2e-53 179.3 0.8 2.2 2 0 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.26 EIE78971.1 - 4.4e-15 55.1 1.0 4.4e-15 55.1 0.7 2.5 3 0 0 3 3 3 1 DnaJ domain DUF3450 PF11932.3 EIE78971.1 - 0.1 11.8 3.9 1.7 7.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) LMBR1 PF04791.11 EIE78971.1 - 0.31 9.5 0.8 0.44 9.0 0.6 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein CagY_M PF07337.6 EIE78971.1 - 0.63 9.5 5.7 0.15 11.6 0.8 2.4 2 0 0 2 2 2 0 DC-EC Repeat GIDA_assoc_3 PF13932.1 EIE78971.1 - 1.7 8.7 4.9 1.7 8.7 0.5 2.7 3 0 0 3 3 3 0 GidA associated domain 3 Spc24 PF08286.6 EIE78973.1 - 9.4e-08 31.7 5.4 9.4e-08 31.7 3.8 2.6 1 1 1 2 2 2 1 Spc24 subunit of Ndc80 V_ATPase_I PF01496.14 EIE78973.1 - 0.0066 14.3 11.6 0.0072 14.2 8.0 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DHOase PF12890.2 EIE78973.1 - 0.024 14.3 0.8 0.033 13.8 0.5 1.3 1 0 0 1 1 1 0 Dihydro-orotase-like DUF520 PF04461.8 EIE78973.1 - 0.075 12.8 5.8 0.081 12.7 3.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF520) NADPH_Ox PF08414.5 EIE78973.1 - 0.088 12.9 0.6 1 9.5 0.0 2.4 1 1 1 2 2 2 0 Respiratory burst NADPH oxidase HAUS6_N PF14661.1 EIE78973.1 - 0.091 12.0 8.6 0.13 11.6 6.0 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus OmpH PF03938.9 EIE78973.1 - 0.17 11.7 15.7 0.27 11.1 10.9 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Exonuc_VII_L PF02601.10 EIE78973.1 - 0.19 10.8 7.8 0.21 10.7 5.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1664 PF07889.7 EIE78973.1 - 0.2 11.4 12.4 0.24 11.2 3.8 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) ERM PF00769.14 EIE78973.1 - 0.33 10.4 19.9 0.41 10.1 13.8 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Vac_Fusion PF02346.11 EIE78973.1 - 0.34 10.3 8.6 0.043 13.2 1.5 2.7 3 0 0 3 3 3 0 Chordopoxvirus fusion protein Peripla_BP_2 PF01497.13 EIE78973.1 - 0.35 9.9 4.7 0.53 9.3 2.9 1.5 1 1 0 1 1 1 0 Periplasmic binding protein Prominin PF05478.6 EIE78973.1 - 0.55 7.6 9.6 0.7 7.3 6.7 1.1 1 0 0 1 1 1 0 Prominin MCPsignal PF00015.16 EIE78973.1 - 0.68 9.4 8.8 0.99 8.9 6.1 1.2 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF4477 PF14780.1 EIE78973.1 - 0.74 9.1 3.8 0.7 9.2 0.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4477) DUF2353 PF09789.4 EIE78973.1 - 0.99 8.5 17.6 3.6 6.7 10.6 2.0 2 0 0 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) Filo_VP35 PF02097.10 EIE78973.1 - 1 8.5 4.1 2.6 7.1 1.8 2.1 1 1 1 2 2 2 0 Filoviridae VP35 Mgr1 PF08602.5 EIE78973.1 - 1.1 8.1 6.4 0.91 8.4 3.7 1.3 1 1 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit ADIP PF11559.3 EIE78973.1 - 1.3 8.9 21.7 7.6 6.4 6.8 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF2400 PF09674.5 EIE78973.1 - 1.6 8.4 5.8 3 7.4 3.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2400) P4Ha_N PF08336.6 EIE78973.1 - 2.2 8.0 15.1 1.3 8.8 1.8 2.4 1 1 1 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Cortex-I_coil PF09304.5 EIE78973.1 - 2.3 8.3 19.7 0.28 11.2 9.3 2.5 2 1 1 3 3 3 0 Cortexillin I, coiled coil AIF-MLS PF14962.1 EIE78973.1 - 2.8 7.5 8.6 4 7.0 5.9 1.3 1 0 0 1 1 1 0 Mitochondria Localisation Sequence DDE_Tnp_IS66 PF03050.9 EIE78973.1 - 2.8 7.0 9.1 1.1 8.4 4.2 1.7 2 0 0 2 2 2 0 Transposase IS66 family DUF3450 PF11932.3 EIE78973.1 - 3.1 6.9 23.7 1.6 7.9 7.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF2937 PF11157.3 EIE78973.1 - 4.3 6.6 8.0 4.6 6.5 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2937) Rnk_N PF14760.1 EIE78973.1 - 5.1 7.2 7.2 1.9 8.6 1.5 2.7 2 1 0 2 2 2 0 Rnk N-terminus RNA_pol_Rpb1_5 PF04998.12 EIE78973.1 - 6.6 5.8 7.7 8 5.6 5.3 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 APG6 PF04111.7 EIE78973.1 - 7.4 5.5 24.9 11 5.0 17.3 1.5 1 1 0 1 1 1 0 Autophagy protein Apg6 FlaC_arch PF05377.6 EIE78973.1 - 7.9 6.4 19.0 0.55 10.1 2.7 3.5 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Atg14 PF10186.4 EIE78973.1 - 8.2 5.2 13.3 11 4.8 9.2 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 CorA PF01544.13 EIE78973.1 - 9.1 5.2 15.3 3.5 6.5 4.2 2.4 2 1 1 3 3 3 0 CorA-like Mg2+ transporter protein SlyX PF04102.7 EIE78973.1 - 9.9 6.6 17.9 0.42 11.0 2.9 3.3 1 1 1 2 2 1 0 SlyX Vasohibin PF14822.1 EIE78974.1 - 0.12 11.4 0.2 0.16 11.0 0.1 1.1 1 0 0 1 1 1 0 Vasohibin DDE_3 PF13358.1 EIE78975.1 - 2.8e-06 27.1 0.0 5.5e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Pkinase PF00069.20 EIE78976.1 - 1e-70 237.8 0.0 1.6e-70 237.2 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE78976.1 - 3.8e-34 117.9 0.0 6.3e-34 117.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE78976.1 - 3.4e-08 32.7 0.0 2.2e-07 30.1 0.0 2.0 1 1 1 2 2 2 1 Kinase-like UBA_2 PF08587.6 EIE78976.1 - 7.5e-05 22.8 0.0 0.00016 21.7 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) KA1 PF02149.14 EIE78976.1 - 0.00024 20.5 0.1 0.001 18.4 0.0 2.1 2 0 0 2 2 2 1 Kinase associated domain 1 YukC PF10140.4 EIE78976.1 - 0.006 15.2 0.1 0.0095 14.5 0.1 1.2 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC Kdo PF06293.9 EIE78976.1 - 0.023 13.7 0.0 0.041 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIE78976.1 - 0.096 12.4 0.1 0.16 11.6 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family RhoGEF PF00621.15 EIE78977.1 - 4.1e-37 127.8 5.9 4.5e-37 127.6 2.9 2.0 2 0 0 2 2 2 1 RhoGEF domain PH PF00169.24 EIE78977.1 - 9.2e-08 32.2 0.1 9.2e-08 32.2 0.0 3.1 3 1 0 3 3 3 1 PH domain DUF480 PF04337.7 EIE78977.1 - 0.032 14.0 0.1 1.5 8.6 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function, DUF480 DUF3808 PF10300.4 EIE78978.1 - 1.4e-21 76.6 0.2 1.2e-19 70.2 0.1 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3808) Fungal_trans_2 PF11951.3 EIE78978.1 - 0.039 12.5 1.5 0.15 10.5 0.5 1.9 1 1 1 2 2 2 0 Fungal specific transcription factor domain DUF3808 PF10300.4 EIE78979.1 - 0.055 12.0 0.0 0.073 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) HisK_N PF09385.5 EIE78980.1 - 0.37 10.3 4.0 0.49 10.0 0.9 2.1 2 0 0 2 2 2 0 Histidine kinase N terminal Phage_holin PF04688.8 EIE78981.1 - 0.0066 15.9 0.1 0.0098 15.3 0.0 1.3 1 0 0 1 1 1 1 Phage lysis protein, holin RVP PF00077.15 EIE78982.1 - 0.027 14.3 0.0 0.073 12.9 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF2361 PF10153.4 EIE78982.1 - 0.11 12.6 2.9 0.26 11.5 2.0 1.7 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2361) Rota_NS35 PF02509.9 EIE78984.1 - 0.11 11.2 0.0 0.14 10.8 0.0 1.1 1 0 0 1 1 1 0 Rotavirus non-structural protein 35 Nucleos_tra2_C PF07662.8 EIE78985.1 - 1.4e-67 227.2 8.7 1.4e-67 227.2 6.0 2.6 4 0 0 4 4 4 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 EIE78985.1 - 9.5e-20 70.7 5.7 9.5e-20 70.7 3.9 3.7 5 0 0 5 5 5 1 Na+ dependent nucleoside transporter N-terminus Sec2p PF06428.6 EIE78986.1 - 8.5e-15 54.4 6.2 2.6e-14 52.8 4.3 1.8 1 0 0 1 1 1 1 GDP/GTP exchange factor Sec2p YPEB PF14620.1 EIE78986.1 - 0.0059 15.6 1.2 0.01 14.8 0.8 1.4 1 0 0 1 1 1 1 YpeB sporulation CENP-Q PF13094.1 EIE78986.1 - 0.035 14.1 18.3 0.066 13.2 12.7 1.4 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit HAUS-augmin3 PF14932.1 EIE78986.1 - 0.05 12.7 10.9 0.088 11.9 7.6 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 IFT57 PF10498.4 EIE78986.1 - 0.15 10.8 10.9 0.16 10.7 6.7 1.5 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 AAA_13 PF13166.1 EIE78986.1 - 0.15 10.4 7.8 0.26 9.7 5.4 1.3 1 0 0 1 1 1 0 AAA domain DUF3584 PF12128.3 EIE78986.1 - 0.25 8.6 14.7 0.36 8.0 10.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Spc7 PF08317.6 EIE78986.1 - 0.27 9.8 11.5 0.52 8.9 8.0 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein THOC7 PF05615.8 EIE78986.1 - 0.47 10.7 15.1 0.2 11.9 8.3 2.0 2 0 0 2 2 2 0 Tho complex subunit 7 ADIP PF11559.3 EIE78986.1 - 0.83 9.5 15.9 2.4 8.0 11.0 1.8 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.4 EIE78986.1 - 1.6 8.5 26.8 1.4 8.7 14.1 2.7 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1640 PF07798.6 EIE78986.1 - 1.8 8.5 15.5 5.8 6.9 10.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) ATG16 PF08614.6 EIE78986.1 - 2.2 8.0 21.2 0.41 10.4 6.9 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF1759 PF03564.10 EIE78986.1 - 3.3 7.5 7.4 11 5.8 1.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1759) AATF-Che1 PF13339.1 EIE78986.1 - 5.1 7.2 11.4 0.63 10.1 0.4 3.4 2 1 1 3 3 3 0 Apoptosis antagonizing transcription factor NIF PF03031.13 EIE78987.1 - 1.5e-20 73.4 0.0 2.6e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Glyco_tranf_2_3 PF13641.1 EIE78988.1 - 2.1e-19 70.2 0.0 2.8e-19 69.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EIE78988.1 - 7e-07 28.6 0.5 1.3e-05 24.5 0.3 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EIE78988.1 - 5.4e-06 26.1 0.0 9.5e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.4 EIE78988.1 - 0.15 11.1 0.1 0.24 10.4 0.1 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 FAST_1 PF06743.10 EIE78989.1 - 0.059 13.0 0.1 0.28 10.9 0.0 2.2 2 0 0 2 2 2 0 FAST kinase-like protein, subdomain 1 PLA2_B PF01735.13 EIE78990.1 - 1.6e-22 79.3 7.9 3.2e-08 32.1 0.9 3.7 4 0 0 4 4 4 3 Lysophospholipase catalytic domain DUF3912 PF13051.1 EIE78990.1 - 0.23 11.2 1.0 1.7 8.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3912) DUF4586 PF15239.1 EIE78991.1 - 0.059 12.9 0.7 0.063 12.8 0.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4586) RanGAP1_C PF07834.6 EIE78991.1 - 0.088 12.2 0.0 0.098 12.0 0.0 1.0 1 0 0 1 1 1 0 RanGAP1 C-terminal domain CRM1_C PF08767.6 EIE78992.1 - 7.8e-128 425.8 0.6 7.8e-128 425.8 0.4 3.8 4 2 1 5 5 5 1 CRM1 C terminal Xpo1 PF08389.7 EIE78992.1 - 7.7e-40 136.2 11.0 6.4e-39 133.2 3.0 4.6 4 0 0 4 4 4 1 Exportin 1-like protein IBN_N PF03810.14 EIE78992.1 - 2.9e-12 46.3 0.5 1.5e-11 44.0 0.3 2.4 1 0 0 1 1 1 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.2 EIE78992.1 - 0.33 11.3 3.7 2.3 8.6 0.1 4.4 6 0 0 6 6 6 0 Vacuolar 14 Fab1-binding region Glyco_transf_49 PF13896.1 EIE78993.1 - 6.4e-44 150.3 0.2 4e-36 124.7 0.1 2.1 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glyco_tranf_2_2 PF10111.4 EIE78993.1 - 0.0002 20.5 0.1 0.00039 19.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EIE78993.1 - 0.0037 16.9 0.3 0.019 14.6 0.1 2.4 1 1 1 2 2 2 1 Glycosyl transferase family 2 Septin PF00735.13 EIE78995.1 - 2.4e-55 187.5 1.0 8.1e-39 133.3 0.4 2.4 3 0 0 3 3 3 2 Septin MMR_HSR1 PF01926.18 EIE78995.1 - 2.3e-05 24.3 0.0 4.3e-05 23.4 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 EIE78995.1 - 3.2e-05 23.6 0.8 0.044 13.3 0.0 3.0 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 EIE78995.1 - 0.0004 19.8 0.1 0.1 12.0 0.1 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 EIE78995.1 - 0.00045 20.2 0.1 0.001 19.1 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain FtsK_SpoIIIE PF01580.13 EIE78995.1 - 0.0012 18.3 0.0 0.0026 17.2 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_33 PF13671.1 EIE78995.1 - 0.0013 18.6 0.0 0.0024 17.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EIE78995.1 - 0.0028 17.3 0.0 0.0057 16.3 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EIE78995.1 - 0.0034 17.5 0.1 0.0094 16.0 0.1 1.8 1 1 0 1 1 1 1 AAA domain MobB PF03205.9 EIE78995.1 - 0.0034 17.0 0.1 0.0085 15.7 0.0 1.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 EIE78995.1 - 0.012 15.4 0.8 2.2 8.0 0.1 2.9 2 1 1 3 3 3 0 Dynamin family UPF0079 PF02367.12 EIE78995.1 - 0.029 14.0 0.1 0.23 11.0 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 EIE78995.1 - 0.036 13.6 0.0 0.082 12.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain cobW PF02492.14 EIE78995.1 - 0.037 13.4 0.8 0.25 10.7 0.3 2.5 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Miro PF08477.8 EIE78995.1 - 0.037 14.5 2.8 0.066 13.7 0.4 2.5 2 1 0 2 2 1 0 Miro-like protein Pox_A32 PF04665.7 EIE78995.1 - 0.043 13.0 0.9 0.15 11.2 0.0 2.0 1 1 1 2 2 2 0 Poxvirus A32 protein ABC_tran PF00005.22 EIE78995.1 - 0.052 13.8 0.1 0.17 12.1 0.0 1.9 2 1 0 2 2 2 0 ABC transporter T2SE PF00437.15 EIE78995.1 - 0.089 11.6 0.0 0.19 10.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF258 PF03193.11 EIE78995.1 - 0.099 11.8 0.2 0.31 10.2 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function, DUF258 NTPase_1 PF03266.10 EIE78995.1 - 0.1 12.3 0.4 2.2 7.9 0.0 2.3 2 0 0 2 2 2 0 NTPase AAA_24 PF13479.1 EIE78995.1 - 0.12 11.9 0.1 0.36 10.3 0.0 1.8 1 1 1 2 2 2 0 AAA domain C2 PF00168.25 EIE78996.1 - 5e-16 58.3 0.0 1.4e-15 56.9 0.0 1.8 1 0 0 1 1 1 1 C2 domain DUF810 PF05664.6 EIE78996.1 - 2.1e-05 23.0 1.7 0.0013 17.1 0.0 3.4 4 0 0 4 4 4 1 Protein of unknown function (DUF810) Membr_traf_MHD PF10540.4 EIE78996.1 - 0.00016 21.4 1.3 0.0013 18.5 0.2 2.7 1 1 1 2 2 2 1 Munc13 (mammalian uncoordinated) homology domain ADH_N PF08240.7 EIE78998.1 - 4.8e-30 103.5 0.4 7.9e-30 102.8 0.3 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIE78998.1 - 9.4e-23 80.1 0.1 1.6e-22 79.4 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Rsa3 PF14615.1 EIE78999.1 - 2.1e-12 46.0 0.0 3.9e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 Ribosome-assembly protein 3 SDA1 PF05285.7 EIE78999.1 - 0.24 10.6 16.3 0.24 10.6 11.3 1.1 1 0 0 1 1 1 0 SDA1 DUF3530 PF12048.3 EIE78999.1 - 0.26 10.2 3.1 0.35 9.7 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Nop14 PF04147.7 EIE78999.1 - 0.33 8.8 21.1 0.36 8.6 14.6 1.0 1 0 0 1 1 1 0 Nop14-like family DUF3408 PF11888.3 EIE78999.1 - 0.35 10.8 8.9 0.44 10.4 6.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Daxx PF03344.10 EIE78999.1 - 0.46 8.8 18.6 0.43 8.9 12.9 1.0 1 0 0 1 1 1 0 Daxx Family DUF2201_N PF13203.1 EIE78999.1 - 0.61 9.1 3.5 0.58 9.2 2.4 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Sigma70_ner PF04546.8 EIE78999.1 - 0.65 9.5 11.8 0.76 9.3 8.2 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region RRN3 PF05327.6 EIE78999.1 - 0.84 7.6 10.0 0.91 7.5 6.9 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Nop53 PF07767.6 EIE78999.1 - 1.3 7.9 14.0 1.7 7.5 9.7 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Nop25 PF09805.4 EIE78999.1 - 1.6 8.8 14.0 2.2 8.3 9.7 1.3 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) YqfQ PF14181.1 EIE78999.1 - 1.8 8.5 6.4 2.7 7.9 4.4 1.5 1 0 0 1 1 1 0 YqfQ-like protein DUF1510 PF07423.6 EIE78999.1 - 1.9 7.8 16.2 2.2 7.5 11.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) COPI_C PF06957.6 EIE78999.1 - 2 6.8 8.5 2.2 6.7 5.9 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Spore_coat_CotO PF14153.1 EIE78999.1 - 2.2 7.7 11.0 2.7 7.3 7.6 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Vfa1 PF08432.5 EIE78999.1 - 3.9 7.4 11.4 4.7 7.1 7.9 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CDC45 PF02724.9 EIE78999.1 - 4.2 5.2 14.7 4.3 5.2 10.2 1.1 1 0 0 1 1 1 0 CDC45-like protein TFIIF_alpha PF05793.7 EIE78999.1 - 4.7 5.4 21.4 5.6 5.2 14.8 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DARPP-32 PF05395.7 EIE78999.1 - 5.1 7.2 15.7 7 6.7 10.9 1.2 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 Myc_N PF01056.13 EIE78999.1 - 7.6 5.6 11.6 8.8 5.3 8.0 1.2 1 0 0 1 1 1 0 Myc amino-terminal region DUF2890 PF11081.3 EIE78999.1 - 9.4 6.2 15.1 11 5.9 10.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) DUF2039 PF10217.4 EIE79000.1 - 1.2e-27 95.6 14.4 1.9e-27 95.1 10.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2039) Bac_small_YrzI PF09501.5 EIE79000.1 - 0.022 14.6 0.7 0.046 13.6 0.5 1.6 1 0 0 1 1 1 0 Probable sporulation protein (Bac_small_yrzI) E6 PF00518.12 EIE79000.1 - 0.78 10.1 10.1 6.5 7.1 2.7 2.3 1 1 1 2 2 2 0 Early Protein (E6) Cript PF10235.4 EIE79000.1 - 3 8.2 16.6 15 5.9 11.5 2.1 1 1 0 1 1 1 0 Microtubule-associated protein CRIPT zf-dskA_traR PF01258.12 EIE79000.1 - 5.1 6.9 8.2 6.1 6.6 0.1 3.5 4 0 0 4 4 4 0 Prokaryotic dksA/traR C4-type zinc finger OST3_OST6 PF04756.8 EIE79001.1 - 1.3e-21 76.8 5.9 1.3e-21 76.8 4.1 1.6 2 0 0 2 2 2 1 OST3 / OST6 family Thioredoxin PF00085.15 EIE79001.1 - 0.00037 20.1 0.0 0.00053 19.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin DUF3188 PF11384.3 EIE79001.1 - 0.056 13.0 0.4 9.7 5.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3188) DUF4131 PF13567.1 EIE79001.1 - 5.4 6.3 13.0 8.2 5.7 1.2 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) Isy1 PF06246.7 EIE79002.1 - 5.6e-46 157.0 0.5 6.3e-46 156.8 0.3 1.0 1 0 0 1 1 1 1 Isy1-like splicing family RE_Eco29kI PF09517.5 EIE79002.1 - 0.13 11.6 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Eco29kI restriction endonuclease ATP-synt_Eps PF04627.8 EIE79003.1 - 8.3e-25 86.0 2.8 9.6e-25 85.8 1.9 1.0 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain zf-CCHC PF00098.18 EIE79004.1 - 3.2e-52 172.0 47.7 1.8e-08 33.9 0.8 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_2 PF13696.1 EIE79004.1 - 7e-11 41.4 38.5 0.0061 16.0 0.5 7.0 3 2 4 7 7 7 6 Zinc knuckle zf-CCHC_3 PF13917.1 EIE79004.1 - 2.2e-08 33.6 37.4 0.0041 16.8 0.6 6.1 2 2 4 6 6 6 6 Zinc knuckle zf-CCHC_4 PF14392.1 EIE79004.1 - 3.1e-07 29.9 38.9 0.021 14.4 0.2 6.9 6 1 1 7 7 7 6 Zinc knuckle E1-E2_ATPase PF00122.15 EIE79005.1 - 1.4e-25 89.6 0.1 1.4e-25 89.6 0.1 1.9 2 0 0 2 2 2 1 E1-E2 ATPase HAD PF12710.2 EIE79005.1 - 1.6e-14 54.5 0.0 8.5e-14 52.1 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EIE79005.1 - 3.7e-14 53.6 0.0 1.5e-13 51.6 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EIE79005.1 - 0.00084 18.7 0.0 0.0027 17.1 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EIE79005.1 - 0.072 12.6 0.5 0.19 11.2 0.0 1.9 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EIE79005.1 - 0.083 12.8 0.0 0.22 11.5 0.0 1.7 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit NAC PF01849.13 EIE79006.1 - 1.6e-18 65.9 0.4 8.9e-17 60.3 0.0 2.5 2 0 0 2 2 2 1 NAC domain UBA PF00627.26 EIE79006.1 - 9.4e-06 25.3 0.6 2e-05 24.2 0.4 1.6 1 0 0 1 1 1 1 UBA/TS-N domain DUF1151 PF06625.6 EIE79006.1 - 0.015 14.9 1.2 0.03 14.0 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1151) UBA_4 PF14555.1 EIE79006.1 - 0.07 12.6 0.1 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 UBA-like domain Ribosomal_S13 PF00416.17 EIE79006.1 - 0.17 12.3 1.2 1.5 9.3 0.2 2.2 2 0 0 2 2 2 0 Ribosomal protein S13/S18 DUF3987 PF13148.1 EIE79006.1 - 0.31 9.5 5.2 0.42 9.1 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) DUF4637 PF15470.1 EIE79006.1 - 0.38 10.3 7.1 0.53 9.8 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) EBV-NA3 PF05009.7 EIE79006.1 - 0.9 8.7 3.0 1.2 8.3 2.1 1.2 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Spore_coat_CotO PF14153.1 EIE79006.1 - 1.3 8.4 7.3 2.2 7.6 5.1 1.4 1 0 0 1 1 1 0 Spore coat protein CotO Lipase_chap PF03280.9 EIE79006.1 - 1.9 7.9 12.8 0.089 12.3 5.2 1.4 2 0 0 2 2 2 0 Proteobacterial lipase chaperone protein Chalcone PF02431.10 EIE79007.1 - 3e-25 88.7 0.0 3.4e-25 88.5 0.0 1.1 1 0 0 1 1 1 1 Chalcone-flavanone isomerase Phage_Integr_2 PF13009.1 EIE79007.1 - 0.078 11.9 0.8 0.11 11.4 0.4 1.3 1 1 0 1 1 1 0 Putative phage integrase HTH_43 PF09904.4 EIE79007.1 - 0.11 12.2 0.2 0.23 11.2 0.1 1.5 1 1 0 1 1 1 0 Winged helix-turn helix DUF2340 PF10209.4 EIE79007.1 - 0.12 12.5 0.6 0.18 11.9 0.4 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2340) HATPase_c_2 PF13581.1 EIE79007.1 - 0.15 11.8 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain AAA PF00004.24 EIE79008.1 - 5.1e-97 321.1 0.0 2.9e-49 166.6 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EIE79008.1 - 1.2e-16 60.4 0.0 1.6e-09 37.1 0.0 2.6 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EIE79008.1 - 1.3e-12 48.5 0.1 1.8e-06 28.7 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_5 PF07728.9 EIE79008.1 - 4.4e-12 45.9 0.1 4.1e-05 23.3 0.0 3.7 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EIE79008.1 - 1.7e-11 44.4 0.1 0.00092 19.3 0.0 4.6 3 2 1 4 4 3 2 AAA domain AAA_16 PF13191.1 EIE79008.1 - 2.9e-11 43.6 2.6 0.00048 20.1 0.1 4.2 2 2 1 3 3 3 2 AAA ATPase domain AAA_2 PF07724.9 EIE79008.1 - 6.4e-11 42.4 0.0 8.9e-05 22.4 0.0 3.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 EIE79008.1 - 2.6e-10 40.3 0.0 0.00017 21.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 EIE79008.1 - 5.4e-10 38.6 0.0 0.00066 18.8 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin AAA_14 PF13173.1 EIE79008.1 - 8.7e-10 38.5 0.0 0.0012 18.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 EIE79008.1 - 3.8e-09 35.7 0.0 7.5e-05 21.6 0.0 2.4 2 0 0 2 2 2 2 TIP49 C-terminus AAA_25 PF13481.1 EIE79008.1 - 3.8e-08 32.9 5.6 0.35 10.2 0.0 4.5 2 2 2 4 4 4 2 AAA domain IstB_IS21 PF01695.12 EIE79008.1 - 1.8e-07 30.7 0.3 0.011 15.1 0.0 2.6 2 1 0 2 2 2 2 IstB-like ATP binding protein RNA_helicase PF00910.17 EIE79008.1 - 1.8e-07 31.2 0.0 0.022 14.9 0.0 2.8 2 1 0 2 2 2 2 RNA helicase NACHT PF05729.7 EIE79008.1 - 1.9e-07 30.8 0.7 0.084 12.5 0.0 4.4 3 1 1 4 4 4 2 NACHT domain AAA_19 PF13245.1 EIE79008.1 - 1.3e-06 28.0 4.0 0.015 15.0 0.1 3.4 3 1 0 3 3 3 2 Part of AAA domain AAA_28 PF13521.1 EIE79008.1 - 1.5e-06 28.2 0.0 0.08 12.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EIE79008.1 - 1.5e-06 28.5 3.3 0.052 13.8 0.0 3.6 3 0 0 3 3 3 2 AAA domain ABC_tran PF00005.22 EIE79008.1 - 4.1e-06 27.1 0.6 0.28 11.4 0.0 3.9 3 0 0 3 3 3 2 ABC transporter Mg_chelatase PF01078.16 EIE79008.1 - 4.8e-06 25.8 0.3 0.054 12.6 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Cytidylate_kin2 PF13189.1 EIE79008.1 - 6.4e-06 26.1 0.7 0.0012 18.7 0.0 2.9 3 0 0 3 3 2 1 Cytidylate kinase-like family SKI PF01202.17 EIE79008.1 - 8.2e-06 25.7 0.3 0.26 11.1 0.0 3.6 3 0 0 3 3 3 2 Shikimate kinase Sigma54_activat PF00158.21 EIE79008.1 - 5e-05 22.8 0.0 0.23 10.8 0.0 3.7 4 0 0 4 4 4 1 Sigma-54 interaction domain AAA_3 PF07726.6 EIE79008.1 - 7.2e-05 22.4 0.0 0.19 11.3 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) KaiC PF06745.8 EIE79008.1 - 8.8e-05 21.7 0.1 0.84 8.7 0.0 3.6 3 0 0 3 3 3 1 KaiC ATP-synt_ab PF00006.20 EIE79008.1 - 0.00011 21.8 0.0 0.45 9.9 0.0 2.6 3 0 0 3 3 2 2 ATP synthase alpha/beta family, nucleotide-binding domain NB-ARC PF00931.17 EIE79008.1 - 0.00013 20.8 0.0 0.2 10.4 0.0 2.8 3 0 0 3 3 3 2 NB-ARC domain DUF815 PF05673.8 EIE79008.1 - 0.00017 20.6 0.0 0.016 14.1 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Viral_helicase1 PF01443.13 EIE79008.1 - 0.00021 20.9 0.2 1 8.7 0.0 3.1 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Sigma54_activ_2 PF14532.1 EIE79008.1 - 0.00025 21.1 0.0 0.32 11.0 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain Parvo_NS1 PF01057.12 EIE79008.1 - 0.00053 18.9 0.1 0.91 8.3 0.0 2.4 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 UPF0079 PF02367.12 EIE79008.1 - 0.00095 18.7 0.0 0.56 9.8 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 EIE79008.1 - 0.0017 18.0 4.1 2.5 7.7 0.0 4.3 3 3 2 5 5 5 1 Archaeal ATPase AAA_11 PF13086.1 EIE79008.1 - 0.0019 17.8 6.7 0.33 10.4 1.5 3.7 3 1 0 3 3 3 1 AAA domain Rad17 PF03215.10 EIE79008.1 - 0.0023 16.7 0.0 1.3 7.6 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein Bac_DnaA PF00308.13 EIE79008.1 - 0.0025 17.4 0.0 2.3 7.8 0.0 2.7 2 1 0 2 2 2 1 Bacterial dnaA protein PhoH PF02562.11 EIE79008.1 - 0.0031 16.7 0.1 1.2 8.3 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein CPT PF07931.7 EIE79008.1 - 0.0043 16.6 0.0 0.2 11.3 0.0 2.6 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein AAA_24 PF13479.1 EIE79008.1 - 0.0075 15.8 0.2 0.81 9.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AFG1_ATPase PF03969.11 EIE79008.1 - 0.011 14.6 0.0 3.3 6.4 0.0 2.5 2 0 0 2 2 2 0 AFG1-like ATPase PduV-EutP PF10662.4 EIE79008.1 - 0.029 13.8 0.0 9.8 5.6 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Vps4_C PF09336.5 EIE79008.1 - 0.035 13.9 1.0 9.4 6.2 0.0 3.1 3 0 0 3 3 2 0 Vps4 C terminal oligomerisation domain NTPase_1 PF03266.10 EIE79008.1 - 0.11 12.2 6.5 3.5 7.3 0.0 3.7 4 0 0 4 4 3 0 NTPase ResIII PF04851.10 EIE79008.1 - 0.12 12.1 7.7 1.9 8.2 0.0 4.0 3 1 1 4 4 2 0 Type III restriction enzyme, res subunit Ribosomal_60s PF00428.14 EIE79008.1 - 0.63 10.4 12.2 5.9 7.3 3.4 3.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein Ribosomal_L18ae PF01775.12 EIE79009.1 - 3.2e-46 156.2 3.7 4e-46 155.9 2.5 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain DNA_ligase_A_M PF01068.16 EIE79010.1 - 1.1e-43 149.0 0.6 1.7e-43 148.3 0.1 1.5 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EIE79010.1 - 1.3e-22 80.5 0.4 2.1e-21 76.5 0.3 2.2 1 1 0 1 1 1 1 DNA ligase N terminus mRNA_cap_enzyme PF01331.14 EIE79010.1 - 3.3e-07 30.1 1.2 3.4e-06 26.9 0.2 2.5 2 1 0 2 2 2 1 mRNA capping enzyme, catalytic domain Peptidase_M13 PF01431.16 EIE79010.1 - 0.037 13.2 0.0 0.087 11.9 0.0 1.6 1 0 0 1 1 1 0 Peptidase family M13 DUF4618 PF15397.1 EIE79010.1 - 0.36 10.1 4.8 0.46 9.7 1.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) BRCT PF00533.21 EIE79011.1 - 0.00018 21.5 0.3 0.00032 20.7 0.2 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF3401 PF11881.3 EIE79011.1 - 0.0058 16.0 0.0 0.0077 15.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3401) RVT_1 PF00078.22 EIE79014.1 - 2.2e-33 115.4 0.0 3.8e-33 114.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2296 PF10058.4 EIE79015.1 - 0.025 14.3 1.5 0.051 13.3 1.0 1.5 1 0 0 1 1 1 0 Predicted integral membrane metal-binding protein (DUF2296) TMF_TATA_bd PF12325.3 EIE79015.1 - 0.048 13.3 2.6 0.12 12.1 0.7 2.4 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding FtsK_SpoIIIE PF01580.13 EIE79015.1 - 0.051 13.0 0.1 0.081 12.3 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family YPEB PF14620.1 EIE79015.1 - 0.089 11.7 3.3 0.13 11.2 2.3 1.2 1 0 0 1 1 1 0 YpeB sporulation TMF_DNA_bd PF12329.3 EIE79015.1 - 0.093 12.5 2.6 0.29 10.9 1.8 1.9 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding TEX13 PF15186.1 EIE79015.1 - 0.48 9.9 4.5 0.11 12.0 0.7 1.7 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family DUF4407 PF14362.1 EIE79015.1 - 0.92 8.4 6.1 1.7 7.4 4.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) IncA PF04156.9 EIE79015.1 - 0.94 9.0 5.5 2.4 7.6 3.8 1.7 1 1 0 1 1 1 0 IncA protein DDE_3 PF13358.1 EIE79016.1 - 6.1e-32 110.3 0.0 1.2e-31 109.4 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_1 PF01527.15 EIE79016.1 - 4.5e-05 23.3 0.2 0.00011 22.1 0.1 1.6 1 0 0 1 1 1 1 Transposase DDE_Tnp_ISAZ013 PF07592.6 EIE79016.1 - 0.0013 17.5 0.1 1.2 7.8 0.0 2.3 2 0 0 2 2 2 2 Rhodopirellula transposase DDE domain HTH_32 PF13565.1 EIE79016.1 - 0.0022 18.7 0.1 0.026 15.3 0.0 2.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.1 EIE79016.1 - 0.0066 16.4 0.0 0.026 14.5 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_psq PF05225.11 EIE79016.1 - 0.012 15.1 0.2 0.066 12.7 0.1 2.1 2 0 0 2 2 2 0 helix-turn-helix, Psq domain BRO1 PF03097.13 EIE79016.1 - 0.09 11.5 0.3 0.13 11.0 0.2 1.2 1 0 0 1 1 1 0 BRO1-like domain CP12 PF02672.10 EIE79016.1 - 0.092 13.2 1.8 0.27 11.7 1.2 1.7 1 0 0 1 1 1 0 CP12 domain YdjO PF14169.1 EIE79016.1 - 0.1 12.0 0.1 0.26 10.7 0.1 1.6 1 0 0 1 1 1 0 Cold-inducible protein YdjO HTH_23 PF13384.1 EIE79016.1 - 0.12 12.0 0.0 0.41 10.3 0.0 1.9 1 0 0 1 1 1 0 Homeodomain-like domain PRESAN PF09687.5 EIE79016.1 - 0.23 11.5 3.1 3.3 7.7 0.8 2.8 2 1 0 2 2 2 0 Plasmodium RESA N-terminal Phage_lysis PF03245.8 EIE79016.1 - 0.31 11.0 2.2 1.1 9.2 0.5 2.1 2 0 0 2 2 2 0 Bacteriophage Rz lysis protein GCR1_C PF12550.3 EIE79017.1 - 5.1e-26 90.3 0.7 5.1e-25 87.1 0.2 2.6 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes DDE_3 PF13358.1 EIE79019.1 - 4.9e-33 113.9 0.0 9.2e-33 113.0 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.14 EIE79019.1 - 6.4e-06 25.4 0.1 1.7e-05 24.1 0.0 1.7 1 1 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE79019.1 - 0.012 15.7 0.0 0.028 14.5 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain Thy1 PF02511.10 EIE79020.1 - 0.034 13.5 1.8 0.07 12.4 0.3 2.0 2 1 0 2 2 2 0 Thymidylate synthase complementing protein Baculo_VP1054 PF05789.6 EIE79020.1 - 0.11 11.6 0.6 0.17 11.0 0.4 1.3 1 0 0 1 1 1 0 Baculovirus VP1054 protein Melibiase PF02065.13 EIE79021.1 - 5.8e-07 28.5 0.5 1.5e-06 27.2 0.0 1.9 2 1 0 2 2 2 1 Melibiase Glyco_hydro_53 PF07745.8 EIE79021.1 - 0.035 12.9 0.4 0.055 12.2 0.3 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 53 Utp12 PF04003.7 EIE79022.1 - 1.3e-18 66.8 0.1 2.8e-18 65.8 0.0 1.6 1 0 0 1 1 1 1 Dip2/Utp12 Family WD40 PF00400.27 EIE79022.1 - 2.5e-08 33.4 0.0 0.00074 19.3 0.0 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat PLDc PF00614.17 EIE79023.1 - 3.6e-16 58.3 1.0 1.3e-09 37.4 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 EIE79023.1 - 1.2e-11 44.4 0.1 1.8e-07 30.9 0.0 3.3 3 0 0 3 3 3 2 PLD-like domain Nucleoporin_FG PF13634.1 EIE79024.1 - 0.85 9.8 7.1 7.6 6.7 4.9 2.1 1 1 0 1 1 1 0 Nucleoporin FG repeat region Bac_surface_Ag PF01103.18 EIE79025.1 - 7.2e-46 157.1 0.1 9.3e-46 156.7 0.0 1.1 1 0 0 1 1 1 1 Surface antigen ICL PF00463.16 EIE79026.1 - 2.4e-250 831.2 0.3 2.8e-250 831.0 0.2 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 EIE79026.1 - 1.4e-11 44.0 0.1 3.3e-10 39.5 0.1 2.2 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Arg_repressor_C PF02863.13 EIE79026.1 - 0.03 13.7 0.0 0.068 12.6 0.0 1.5 1 0 0 1 1 1 0 Arginine repressor, C-terminal domain GAGA_bind PF06217.7 EIE79027.1 - 1.4 8.7 4.8 1.6 8.5 3.3 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family DUF3959 PF13105.1 EIE79027.1 - 2.4 7.4 5.7 4.2 6.6 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) PRTP PF01366.13 EIE79027.1 - 4 5.3 9.0 5 4.9 6.2 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein Pilt PF15453.1 EIE79027.1 - 6.2 6.4 10.1 9 5.8 7.0 1.2 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions WD40 PF00400.27 EIE79028.1 - 7.8e-28 95.3 19.5 6.4e-10 38.5 0.8 7.2 6 1 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 EIE79028.1 - 0.016 13.3 1.7 0.14 10.2 0.3 2.1 1 1 0 2 2 2 0 Nucleoporin Nup120/160 Kinesin PF00225.18 EIE79029.1 - 3.2e-88 295.6 0.0 5.5e-88 294.8 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Bac_export_3 PF01313.14 EIE79030.1 - 0.0084 15.7 0.2 0.0084 15.7 0.2 2.4 3 0 0 3 3 3 1 Bacterial export proteins, family 3 DUF3852 PF12963.2 EIE79030.1 - 0.054 13.5 2.2 0.061 13.3 0.2 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3852) SSB PF00436.20 EIE79031.1 - 1.8e-21 75.9 0.3 2.1e-21 75.7 0.2 1.1 1 0 0 1 1 1 1 Single-strand binding protein family tRNA_anti-codon PF01336.20 EIE79031.1 - 0.031 14.1 0.1 0.068 13.0 0.0 1.6 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain DUF4131 PF13567.1 EIE79031.1 - 0.045 13.1 0.1 0.057 12.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Lipase_GDSL PF00657.17 EIE79032.1 - 1.3e-07 31.6 0.1 1.8e-07 31.2 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 EIE79032.1 - 1.1e-05 25.2 0.1 9.7e-05 22.1 0.0 2.1 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Fungal_trans PF04082.13 EIE79033.1 - 3.2e-12 45.8 0.4 9.7e-12 44.3 0.2 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Aldo_ket_red PF00248.16 EIE79034.1 - 9.6e-27 93.5 0.1 3.6e-25 88.3 0.0 2.3 1 1 0 1 1 1 1 Aldo/keto reductase family L1R_F9L PF02442.12 EIE79034.1 - 0.0084 15.6 0.7 0.036 13.5 0.0 2.2 2 0 0 2 2 2 1 Lipid membrane protein of large eukaryotic DNA viruses Proteasom_Rpn13 PF04683.8 EIE79035.1 - 1.1e-20 73.4 1.4 3.5e-16 59.0 0.2 2.5 1 1 1 2 2 2 2 Proteasome complex subunit Rpn13 ubiquitin receptor DUF4274 PF14096.1 EIE79035.1 - 0.032 14.0 0.7 0.11 12.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4274) Mannitol_dh PF01232.18 EIE79035.1 - 0.16 11.8 1.2 13 5.6 0.0 2.2 2 0 0 2 2 2 0 Mannitol dehydrogenase Rossmann domain AAA_23 PF13476.1 EIE79035.1 - 7.2 6.8 15.8 76 3.5 11.0 2.0 1 1 0 1 1 1 0 AAA domain RINGv PF12906.2 EIE79036.1 - 3.5e-08 33.3 4.4 6.6e-08 32.4 3.0 1.4 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.3 EIE79036.1 - 0.00049 19.9 2.6 0.00086 19.2 1.8 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.1 EIE79036.1 - 0.0023 17.7 1.2 0.0045 16.7 0.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_4 PF14570.1 EIE79036.1 - 0.014 14.9 1.7 0.026 14.1 1.2 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain SHS2_Rpb7-N PF03876.12 EIE79037.1 - 1.8e-09 37.6 0.1 3.6e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 EIE79037.1 - 0.0037 17.3 0.8 0.67 10.0 0.1 2.4 1 1 1 2 2 2 2 S1 RNA binding domain S-AdoMet_synt_C PF02773.11 EIE79038.1 - 3.2e-77 256.9 0.1 5.5e-77 256.1 0.1 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 EIE79038.1 - 2.4e-47 159.8 0.0 4.9e-47 158.8 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 EIE79038.1 - 1.2e-44 150.6 0.1 2.6e-44 149.5 0.1 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain Mito_carr PF00153.22 EIE79039.1 - 1.8e-37 126.9 1.6 6.4e-12 45.0 0.0 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein Nup35_RRM PF05172.8 EIE79040.1 - 2.8e-07 30.2 0.0 2.7e-06 27.0 0.0 2.2 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.1 EIE79040.1 - 4.2e-06 26.4 0.0 6.9e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DUF1866 PF08952.6 EIE79040.1 - 1.8e-05 24.3 0.0 2.8e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1866) RRM_1 PF00076.17 EIE79040.1 - 0.00016 21.2 0.0 0.00027 20.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE79040.1 - 0.00046 20.1 0.0 0.0009 19.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FSH1 PF03959.8 EIE79041.1 - 6.9e-56 189.0 0.0 7.7e-56 188.8 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 EIE79041.1 - 0.001 18.8 0.0 0.0014 18.3 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIE79041.1 - 0.0029 17.5 0.1 0.049 13.5 0.1 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EIE79041.1 - 0.0047 16.4 0.7 0.048 13.0 0.5 2.1 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Ribosomal_L30 PF00327.15 EIE79041.1 - 0.045 13.3 0.1 0.086 12.4 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L30p/L7e HLH PF00010.21 EIE79042.1 - 2.8e-14 52.5 0.2 2.6e-13 49.4 0.2 2.2 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF4156 PF13698.1 EIE79042.1 - 0.052 13.4 0.1 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4156) HTH_29 PF13551.1 EIE79043.1 - 0.063 13.4 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix rve PF00665.21 EIE79044.1 - 3.1e-23 82.1 0.0 7.5e-23 80.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE79044.1 - 7.4e-16 58.1 0.3 2.1e-15 56.6 0.2 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE79044.1 - 4e-11 42.3 1.1 9.6e-11 41.1 0.7 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.12 EIE79044.1 - 0.00051 20.0 0.8 0.0023 17.9 0.5 2.2 1 0 0 1 1 1 1 Retrotransposon gag protein zf-H2C2 PF09337.5 EIE79044.1 - 0.0014 18.0 0.1 0.0041 16.4 0.1 1.9 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Asp_protease_2 PF13650.1 EIE79044.1 - 0.0052 17.2 0.2 0.014 15.9 0.2 1.8 1 0 0 1 1 1 1 Aspartyl protease rve_3 PF13683.1 EIE79044.1 - 0.0074 15.7 0.1 0.05 13.1 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain DUF2246 PF10229.4 EIE79044.1 - 0.0076 15.5 0.8 0.039 13.2 0.1 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2246) UBN2_2 PF14227.1 EIE79044.1 - 0.0096 15.4 4.9 0.036 13.6 0.0 3.4 3 0 0 3 3 3 1 gag-polypeptide of LTR copia-type Asp_protease PF09668.5 EIE79044.1 - 0.04 13.4 0.1 0.12 11.9 0.1 1.9 1 1 0 1 1 1 0 Aspartyl protease DDE_Tnp_IS1595 PF12762.2 EIE79046.1 - 0.00088 19.1 0.1 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 ISXO2-like transposase domain HTH_24 PF13412.1 EIE79046.1 - 0.12 11.7 0.0 0.3 10.5 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding rve PF00665.21 EIE79047.1 - 1.4e-12 47.8 0.0 7e-12 45.5 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 EIE79047.1 - 7.4e-11 41.8 0.4 4.3e-10 39.3 0.2 2.2 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP PF00077.15 EIE79047.1 - 0.0016 18.3 0.2 0.007 16.2 0.1 2.2 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 EIE79047.1 - 0.0033 17.8 0.1 0.0072 16.7 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.12 EIE79047.1 - 0.024 14.6 0.0 0.19 11.8 0.0 2.6 1 1 0 1 1 1 0 Retrotransposon gag protein NicO PF03824.11 EIE79048.1 - 2.4e-75 253.4 17.2 2.7e-75 253.3 12.0 1.0 1 0 0 1 1 1 1 High-affinity nickel-transport protein NifZ PF04319.8 EIE79048.1 - 0.02 14.2 0.0 0.042 13.2 0.0 1.5 1 0 0 1 1 1 0 NifZ domain LRRC37AB_C PF14914.1 EIE79048.1 - 3.1 7.2 5.3 12 5.3 0.7 2.3 2 0 0 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain Ribosomal_S7 PF00177.16 EIE79049.1 - 1.4e-39 134.9 0.3 1.7e-39 134.7 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e His_Phos_2 PF00328.17 EIE79050.1 - 6.8e-73 245.9 0.4 9e-73 245.5 0.3 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 EIE79050.1 - 3.3e-08 33.2 0.0 7e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain His_Phos_1 PF00300.17 EIE79050.1 - 0.06 13.4 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) Orbi_VP7 PF00897.12 EIE79053.1 - 0.12 11.3 0.0 0.12 11.3 0.0 1.0 1 0 0 1 1 1 0 Orbivirus inner capsid protein VP7 HTH_29 PF13551.1 EIE79054.1 - 3.7e-08 33.5 0.0 5.7e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.1 EIE79054.1 - 6.4e-06 26.0 0.1 3.9e-05 23.5 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.1 EIE79054.1 - 4.2e-05 23.0 0.2 0.0064 16.1 0.0 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.1 EIE79054.1 - 0.00021 22.0 0.0 0.0004 21.1 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_17 PF12728.2 EIE79054.1 - 0.0093 16.2 0.0 4.7 7.5 0.0 2.5 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_Tnp_1 PF01527.15 EIE79054.1 - 0.011 15.7 0.0 0.093 12.7 0.0 2.1 2 0 0 2 2 2 0 Transposase HTH_Tnp_Tc3_2 PF01498.13 EIE79054.1 - 0.016 15.2 0.2 0.044 13.8 0.0 1.9 2 0 0 2 2 2 0 Transposase Terminase_1 PF03354.10 EIE79054.1 - 0.028 12.8 0.0 0.039 12.3 0.0 1.1 1 0 0 1 1 1 0 Phage Terminase LZ_Tnp_IS481 PF13011.1 EIE79054.1 - 0.051 13.9 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 PHD PF00628.24 EIE79055.1 - 6.8e-10 38.4 9.6 1.5e-09 37.3 6.6 1.6 1 0 0 1 1 1 1 PHD-finger SET PF00856.23 EIE79055.1 - 7.1e-07 29.6 0.7 1.5e-05 25.3 0.1 3.0 2 1 0 2 2 2 1 SET domain PHD_2 PF13831.1 EIE79055.1 - 0.2 11.0 6.5 0.43 9.9 4.5 1.5 1 0 0 1 1 1 0 PHD-finger FAM176 PF14851.1 EIE79055.1 - 0.58 9.8 6.3 2.7 7.6 1.2 2.5 2 0 0 2 2 2 0 FAM176 family ArgJ PF01960.13 EIE79056.1 - 1.3e-153 511.0 5.3 1.5e-153 510.8 3.7 1.0 1 0 0 1 1 1 1 ArgJ family Cadherin-like PF12733.2 EIE79056.1 - 0.053 13.7 0.0 6.2 7.1 0.0 2.6 2 0 0 2 2 2 0 Cadherin-like beta sandwich domain DNA_pol_B PF00136.16 EIE79057.1 - 1.7e-143 478.8 0.6 2.6e-143 478.2 0.4 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EIE79057.1 - 4.1e-81 272.3 0.0 1.2e-80 270.8 0.0 1.8 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 EIE79057.1 - 1.8e-22 79.0 7.5 4.1e-22 77.9 5.2 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta HD_2 PF12917.2 EIE79057.1 - 0.00026 20.8 0.9 0.0055 16.5 0.2 3.0 3 0 0 3 3 3 1 HD containing hydrolase-like enzyme DNA_pol_B_exo2 PF10108.4 EIE79057.1 - 0.0029 17.1 0.0 0.0055 16.2 0.0 1.4 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 EIE79057.1 - 0.011 15.4 0.1 0.041 13.6 0.0 2.0 1 1 0 1 1 1 0 RNase_H superfamily zf-RING-like PF08746.6 EIE79057.1 - 0.028 14.3 1.2 0.11 12.5 0.8 2.1 1 0 0 1 1 1 0 RING-like domain C1_1 PF00130.17 EIE79057.1 - 0.075 12.7 6.1 0.32 10.7 4.2 2.0 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DNA_pol_B_2 PF03175.8 EIE79057.1 - 0.084 11.5 3.9 0.15 10.6 0.0 2.6 3 0 0 3 3 3 0 DNA polymerase type B, organellar and viral DZR PF12773.2 EIE79057.1 - 2.5 8.0 7.3 11 5.9 5.1 2.0 1 1 0 1 1 1 0 Double zinc ribbon DDE_3 PF13358.1 EIE79059.1 - 9.3e-22 77.3 0.1 1.3e-21 76.8 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE79059.1 - 0.0014 18.7 0.0 0.0043 17.1 0.0 1.9 1 1 0 1 1 1 1 Integrase core domain HMG_box_2 PF09011.5 EIE79059.1 - 0.019 15.3 0.3 0.044 14.1 0.2 1.6 1 0 0 1 1 1 0 HMG-box domain THP2 PF09432.5 EIE79059.1 - 0.025 14.4 0.4 0.24 11.2 0.0 2.2 2 0 0 2 2 2 0 Tho complex subunit THP2 Viral_DNA_bi PF02236.12 EIE79059.1 - 0.12 12.5 0.4 1.6 8.9 0.0 2.3 2 0 0 2 2 2 0 Viral DNA-binding protein, all alpha domain Chromo PF00385.19 EIE79060.1 - 8.1e-12 44.6 0.6 1.9e-11 43.4 0.4 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DDE_3 PF13358.1 EIE79061.1 - 6.3e-21 74.6 0.1 1e-20 73.9 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE79061.1 - 3.8e-15 55.6 0.2 9.2e-15 54.4 0.2 1.7 1 0 0 1 1 1 1 Transposase Ku_PK_bind PF08785.6 EIE79061.1 - 0.0059 16.4 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 Ku C terminal domain like HTH_29 PF13551.1 EIE79061.1 - 0.047 13.8 0.1 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn helix DDE_Tnp_IS1595 PF12762.2 EIE79062.1 - 1.2e-22 80.4 0.8 2.1e-22 79.6 0.3 1.6 2 0 0 2 2 2 1 ISXO2-like transposase domain HTH_Tnp_Tc3_2 PF01498.13 EIE79063.1 - 2.4e-06 27.4 0.1 2.7e-06 27.3 0.1 1.1 1 0 0 1 1 1 1 Transposase RVT_1 PF00078.22 EIE79064.1 - 1.1e-17 64.1 0.1 2.4e-17 63.0 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.5 EIE79064.1 - 3.7e-05 23.0 0.2 8.3e-05 21.9 0.1 1.7 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger RNase_H PF00075.19 EIE79064.1 - 0.065 13.5 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 RNase H zf-CCHC PF00098.18 EIE79066.1 - 4.5e-09 35.8 9.0 1.1e-05 25.0 0.7 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.1 EIE79066.1 - 0.0004 19.8 4.8 0.0025 17.2 0.6 2.5 1 1 1 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.1 EIE79066.1 - 0.0015 18.1 7.8 0.39 10.4 2.1 2.7 2 1 0 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.1 EIE79066.1 - 0.0022 17.6 8.5 0.089 12.4 0.8 2.4 1 1 1 2 2 2 2 Zinc knuckle DnaJ_CXXCXGXG PF00684.14 EIE79066.1 - 0.017 15.1 2.8 0.65 10.0 2.3 2.2 1 1 1 2 2 2 0 DnaJ central domain Zn_ribbon_2 PF12674.2 EIE79066.1 - 0.29 11.5 2.6 0.66 10.3 1.8 1.8 1 1 0 1 1 1 0 Putative zinc ribbon domain Cmc1 PF08583.5 EIE79066.1 - 0.47 10.2 3.8 0.68 9.7 2.6 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like zf-CCHC_3 PF13917.1 EIE79066.1 - 2.1 8.1 6.6 1.9 8.3 0.5 2.3 1 1 1 2 2 2 0 Zinc knuckle IBR PF01485.16 EIE79066.1 - 9 6.2 10.1 66 3.4 7.0 2.1 1 1 0 1 1 1 0 IBR domain DDE_3 PF13358.1 EIE79067.1 - 5e-20 71.7 0.1 8.1e-20 71.0 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE79067.1 - 3.9e-17 62.0 3.4 4.4e-17 61.9 0.1 2.6 3 1 1 4 4 4 1 Transposase HTH_29 PF13551.1 EIE79067.1 - 9e-08 32.2 1.1 2.4e-07 30.8 0.5 1.9 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.1 EIE79067.1 - 2.1e-05 25.2 1.0 0.0043 17.8 0.1 3.3 2 1 1 3 3 3 1 Homeodomain-like domain HTH_23 PF13384.1 EIE79067.1 - 5.7e-05 22.6 0.2 0.0012 18.3 0.0 3.0 4 0 0 4 4 4 1 Homeodomain-like domain HTH_28 PF13518.1 EIE79067.1 - 0.002 18.1 0.1 0.014 15.4 0.0 2.5 3 0 0 3 3 3 1 Helix-turn-helix domain Ribonucleas_3_2 PF11469.3 EIE79067.1 - 0.06 13.5 0.1 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Ribonuclease III NUMOD3 PF07460.6 EIE79067.1 - 0.081 12.8 0.3 0.23 11.3 0.0 1.9 2 0 0 2 2 2 0 NUMOD3 motif (2 copies) HTH_7 PF02796.10 EIE79067.1 - 0.18 11.6 0.7 2 8.3 0.1 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase DDE_3 PF13358.1 EIE79071.1 - 9e-18 64.4 0.2 1.2e-17 64.0 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE79071.1 - 0.0029 17.7 0.0 0.0041 17.2 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain HMG_box_2 PF09011.5 EIE79071.1 - 0.013 15.8 0.3 0.024 15.0 0.2 1.5 1 0 0 1 1 1 0 HMG-box domain THP2 PF09432.5 EIE79071.1 - 0.013 15.3 0.4 0.14 11.9 0.1 2.1 2 0 0 2 2 2 0 Tho complex subunit THP2 Viral_DNA_bi PF02236.12 EIE79071.1 - 0.051 13.7 0.3 0.98 9.6 0.0 2.2 2 0 0 2 2 2 0 Viral DNA-binding protein, all alpha domain HMG_box PF00505.14 EIE79071.1 - 0.065 13.5 0.9 0.14 12.4 0.6 1.7 1 1 0 1 1 1 0 HMG (high mobility group) box PH_7 PF15408.1 EIE79071.1 - 0.23 11.3 1.0 0.62 9.9 0.0 2.1 2 1 1 3 3 3 0 Pleckstrin homology domain DDE_3 PF13358.1 EIE79072.1 - 0.0053 16.5 0.0 0.0074 16.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE79073.1 - 1.6e-24 86.3 0.0 5.2e-24 84.6 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE79073.1 - 6.1e-17 61.6 0.0 1.2e-16 60.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.5 EIE79073.1 - 0.00037 19.8 0.1 0.00097 18.4 0.1 1.8 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger rve_3 PF13683.1 EIE79073.1 - 0.024 14.1 0.0 0.081 12.4 0.0 1.9 1 0 0 1 1 1 0 Integrase core domain DDE_Tnp_IS1595 PF12762.2 EIE79074.1 - 2.5e-07 30.6 0.1 4.6e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 ISXO2-like transposase domain DDE_3 PF13358.1 EIE79077.1 - 4.2e-09 36.3 0.1 6.2e-05 22.7 0.1 2.3 1 1 1 2 2 2 2 DDE superfamily endonuclease NUDIX_4 PF14815.1 EIE79077.1 - 0.04 13.3 0.1 0.053 12.9 0.1 1.2 1 0 0 1 1 1 0 NUDIX domain DDE_Tnp_IS1595 PF12762.2 EIE79078.1 - 3.5e-18 65.8 2.4 2.2e-12 47.0 0.1 3.1 2 1 0 2 2 2 2 ISXO2-like transposase domain DDE_3 PF13358.1 EIE79080.1 - 6.8e-13 48.6 0.0 9.7e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease RVT_1 PF00078.22 EIE79081.1 - 8.1e-15 54.7 0.3 8.4e-07 28.5 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Spuma_A9PTase PF03539.9 EIE79081.1 - 0.025 14.4 0.2 0.083 12.8 0.0 1.9 1 1 1 2 2 2 0 Spumavirus aspartic protease (A9) zf-H2C2 PF09337.5 EIE79082.1 - 0.0015 17.9 0.2 0.003 16.9 0.1 1.6 1 1 0 1 1 1 1 His(2)-Cys(2) zinc finger zf-3CxxC PF13695.1 EIE79082.1 - 0.078 13.2 0.1 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding domain DDE_3 PF13358.1 EIE79086.1 - 8.7e-21 74.2 0.4 1.2e-20 73.7 0.3 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Chromo PF00385.19 EIE79087.1 - 2.4e-14 52.7 2.2 2.4e-14 52.7 1.5 1.8 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain DDE_Tnp_IS1595 PF12762.2 EIE79088.1 - 0.00087 19.1 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 ISXO2-like transposase domain rve PF00665.21 EIE79091.1 - 7.4e-17 61.5 0.0 3.8e-16 59.2 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.19 EIE79091.1 - 7.9e-09 35.0 0.2 2.7e-08 33.3 0.1 2.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVT_1 PF00078.22 EIE79091.1 - 6.4e-08 32.2 0.5 6.5e-07 28.9 0.2 2.7 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP PF00077.15 EIE79091.1 - 0.0015 18.4 0.2 0.0071 16.2 0.1 2.3 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 EIE79091.1 - 0.0035 17.8 0.1 0.0073 16.7 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease DDE_3 PF13358.1 EIE79092.1 - 8.9e-13 48.2 0.0 1.2e-12 47.8 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF2567 PF10821.3 EIE79092.1 - 0.019 14.5 0.0 0.023 14.1 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2567) DUF3854 PF12965.2 EIE79092.1 - 0.13 11.9 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3854) DUF1759 PF03564.10 EIE79094.1 - 0.0021 17.8 0.2 0.0067 16.2 0.2 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) DUF4524 PF15025.1 EIE79094.1 - 0.035 13.5 2.3 0.073 12.5 1.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4524) RVT_1 PF00078.22 EIE79095.1 - 7e-13 48.4 0.2 1e-08 34.7 0.0 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 EIE79095.1 - 3.2e-07 30.7 0.0 7.3e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EIE79095.1 - 2.9e-05 23.8 0.1 5.5e-05 22.8 0.1 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.5 EIE79095.1 - 3.5e-05 23.3 0.0 7.3e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 EIE79095.1 - 0.0048 16.8 0.0 0.014 15.2 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease HTH_Tnp_Tc3_2 PF01498.13 EIE79098.1 - 7.2e-15 54.8 1.1 1.3e-14 54.0 0.7 1.4 1 0 0 1 1 1 1 Transposase HTH_Tnp_Tc3_2 PF01498.13 EIE79100.1 - 5.1e-09 36.0 1.4 8.1e-09 35.4 0.7 1.6 1 1 1 2 2 2 1 Transposase DDE_Tnp_IS1595 PF12762.2 EIE79101.1 - 1.9e-07 31.0 0.1 3.5e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 ISXO2-like transposase domain DUF1759 PF03564.10 EIE79105.1 - 0.00014 21.7 0.5 0.00018 21.3 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) Retrotrans_gag PF03732.12 EIE79105.1 - 0.015 15.3 0.1 0.034 14.2 0.0 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein Sigma70_r1_1 PF03979.9 EIE79105.1 - 0.16 11.9 0.2 0.26 11.2 0.1 1.3 1 0 0 1 1 1 0 Sigma-70 factor, region 1.1 Utp11 PF03998.8 EIE79107.1 - 0.1 12.3 2.1 0.12 12.1 1.5 1.2 1 0 0 1 1 1 0 Utp11 protein EcoR124_C PF12008.3 EIE79109.1 - 0.015 14.5 3.6 0.017 14.3 2.5 1.0 1 0 0 1 1 1 0 Type I restriction and modification enzyme - subunit R C terminal Zn_ribbon_2 PF12674.2 EIE79109.1 - 0.028 14.7 1.6 0.068 13.5 0.2 1.9 2 0 0 2 2 2 0 Putative zinc ribbon domain AAA_27 PF13514.1 EIE79109.1 - 0.03 12.0 2.4 0.035 11.8 1.7 1.1 1 0 0 1 1 1 0 AAA domain Mnd1 PF03962.10 EIE79109.1 - 0.058 13.0 2.9 0.075 12.6 2.0 1.2 1 0 0 1 1 1 0 Mnd1 family SMC_Nse1 PF07574.8 EIE79109.1 - 0.085 12.4 1.3 0.097 12.2 0.9 1.1 1 0 0 1 1 1 0 Nse1 non-SMC component of SMC5-6 complex Swi5 PF07061.6 EIE79109.1 - 0.087 12.6 1.6 0.49 10.2 0.1 2.1 2 0 0 2 2 2 0 Swi5 PRP1_N PF06424.7 EIE79109.1 - 0.18 12.1 3.6 0.29 11.4 2.5 1.4 1 1 0 1 1 1 0 PRP1 splicing factor, N-terminal DUF2497 PF10691.4 EIE79109.1 - 0.19 11.7 1.1 0.58 10.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2497) EF-hand_like PF09279.6 EIE79109.1 - 0.71 9.9 3.6 13 5.8 0.6 2.1 2 0 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like UvrB PF12344.3 EIE79109.1 - 6.2 6.4 6.3 10 5.7 1.3 2.3 2 0 0 2 2 2 0 Ultra-violet resistance protein B Srg PF02118.16 EIE79110.1 - 0.083 12.3 0.1 0.091 12.1 0.0 1.0 1 0 0 1 1 1 0 Srg family chemoreceptor NtA PF03146.10 EIE79110.1 - 0.088 12.4 0.0 0.1 12.2 0.0 1.1 1 0 0 1 1 1 0 Agrin NtA domain Mss4 PF04421.8 EIE79110.1 - 0.14 11.9 0.2 0.16 11.8 0.1 1.2 1 0 0 1 1 1 0 Mss4 protein Fer2_3 PF13085.1 EIE79111.1 - 8.1e-32 109.3 0.0 1.3e-31 108.6 0.0 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 EIE79111.1 - 2.3e-10 40.6 8.0 2.3e-10 40.6 5.6 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 EIE79111.1 - 2.7e-08 33.6 5.8 2.7e-08 33.6 4.0 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 EIE79111.1 - 8.7e-05 22.8 2.9 8.7e-05 22.8 2.0 2.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 EIE79111.1 - 0.00013 21.6 5.6 0.00013 21.6 3.9 2.4 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.22 EIE79111.1 - 0.00059 19.5 3.1 0.0037 16.9 0.2 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_9 PF13187.1 EIE79111.1 - 0.0012 19.0 9.7 0.04 14.1 0.4 3.2 3 1 0 3 3 3 2 4Fe-4S dicluster domain Fer4_7 PF12838.2 EIE79111.1 - 0.0017 18.7 6.6 0.0017 18.7 4.5 2.5 2 2 0 2 2 2 1 4Fe-4S dicluster domain DNA_pol3_tau_4 PF12168.3 EIE79111.1 - 0.24 11.8 1.3 0.47 10.8 0.0 2.1 3 0 0 3 3 3 0 DNA polymerase III subunits tau domain IV DnaB-binding Fer4_15 PF13459.1 EIE79111.1 - 2.6 8.6 7.1 1.2 9.7 0.1 2.7 3 0 0 3 3 3 0 4Fe-4S single cluster domain Peptidase_S8 PF00082.17 EIE79112.1 - 8e-41 140.0 5.4 8e-41 140.0 3.7 1.9 2 1 0 2 2 2 1 Subtilase family FH2 PF02181.18 EIE79113.1 - 2e-24 86.2 36.9 2.1e-14 53.2 0.8 6.3 3 1 3 6 6 6 4 Formin Homology 2 Domain Drf_FH3 PF06367.11 EIE79113.1 - 5.6e-22 78.1 2.2 5.6e-22 78.1 1.5 2.4 2 0 0 2 2 2 1 Diaphanous FH3 Domain Drf_GBD PF06371.8 EIE79113.1 - 5.9e-05 22.5 11.4 0.00016 21.1 2.2 4.0 2 1 0 2 2 2 1 Diaphanous GTPase-binding Domain Peptidase_M16_C PF05193.16 EIE79114.1 - 8.4e-49 165.7 0.0 1.3e-48 165.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EIE79114.1 - 1.6e-44 151.2 0.0 5.1e-44 149.6 0.0 1.8 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Pkinase PF00069.20 EIE79115.1 - 1.1e-51 175.5 0.0 1.4e-51 175.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE79115.1 - 3.1e-25 88.7 0.0 4.3e-25 88.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE79115.1 - 0.00028 19.9 0.0 0.00085 18.3 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Pox_ser-thr_kin PF05445.6 EIE79115.1 - 0.0013 17.6 0.6 0.0022 16.8 0.3 1.4 1 1 0 1 1 1 1 Poxvirus serine/threonine protein kinase DUF2763 PF10961.3 EIE79115.1 - 0.068 13.5 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2763) MFS_1 PF07690.11 EIE79116.1 - 1.2e-39 136.0 33.6 1.2e-39 136.0 23.3 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIE79116.1 - 2.9e-13 49.1 5.0 2.9e-13 49.1 3.4 3.1 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EIE79116.1 - 1.8e-10 39.6 7.5 1.8e-10 39.6 5.2 2.2 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF770 PF05591.7 EIE79118.1 - 0.12 11.8 0.2 0.15 11.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF770) Alg6_Alg8 PF03155.10 EIE79119.1 - 5.5e-40 137.6 13.4 7.9e-40 137.0 4.7 2.0 1 1 1 2 2 2 2 ALG6, ALG8 glycosyltransferase family Homeobox PF00046.24 EIE79120.1 - 4.7e-20 70.9 2.2 1.1e-19 69.7 1.5 1.7 1 0 0 1 1 1 1 Homeobox domain PH PF00169.24 EIE79121.1 - 5.8e-06 26.4 1.4 4.2e-05 23.7 0.6 2.5 2 1 0 2 2 2 1 PH domain tRNA-synt_1c_C PF03950.13 EIE79121.1 - 0.054 13.1 0.3 0.066 12.8 0.2 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), anti-codon binding domain SAM_2 PF07647.12 EIE79122.1 - 8.2e-10 38.3 0.3 2.2e-09 37.0 0.1 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EIE79122.1 - 2.4e-07 30.7 1.2 3.9e-07 30.1 0.1 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Zip PF02535.17 EIE79122.1 - 0.017 14.1 2.5 0.022 13.7 1.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Lipase_GDSL PF00657.17 EIE79123.1 - 5.9e-09 36.0 0.0 8.6e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EIE79123.1 - 0.0026 17.9 0.0 0.0059 16.7 0.0 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family VPS28 PF03997.7 EIE79123.1 - 0.053 13.1 0.1 0.12 12.0 0.1 1.6 2 0 0 2 2 2 0 VPS28 protein DUF2464 PF10240.4 EIE79124.1 - 0.00077 18.8 0.0 0.0013 18.1 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2464) DUF3759 PF12585.3 EIE79126.1 - 3.7e-37 126.1 7.4 4.2e-37 125.9 5.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) SRP40_C PF05022.7 EIE79126.1 - 0.038 14.4 0.1 0.057 13.9 0.1 1.4 1 0 0 1 1 1 0 SRP40, C-terminal domain MFS_1 PF07690.11 EIE79127.1 - 3.3e-13 49.0 25.9 3.3e-13 49.0 18.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 EIE79127.1 - 9.2e-10 38.2 3.7 9.2e-10 38.2 2.6 2.8 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 DUF2370 PF10176.4 EIE79127.1 - 0.014 14.7 0.9 0.22 10.8 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) HEAT_2 PF13646.1 EIE79128.1 - 6.7e-05 23.0 0.0 0.86 9.9 0.0 4.2 2 2 2 4 4 4 2 HEAT repeats Arm PF00514.18 EIE79128.1 - 0.00017 21.2 0.6 0.03 14.1 0.0 4.6 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 EIE79128.1 - 0.091 13.2 2.6 1.4 9.5 0.1 4.2 5 1 1 6 6 6 0 HEAT-like repeat Aminotran_1_2 PF00155.16 EIE79131.1 - 2e-21 76.3 0.0 2.6e-21 75.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 EIE79131.1 - 2.4e-10 39.5 0.0 3.2e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase KH_dom-like PF14714.1 EIE79131.1 - 0.035 14.0 0.0 6.8 6.7 0.0 2.6 2 0 0 2 2 2 0 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal Ctr PF04145.10 EIE79132.1 - 1.2e-24 86.9 3.5 1.4e-24 86.7 2.4 1.2 1 0 0 1 1 1 1 Ctr copper transporter family Sec15 PF04091.7 EIE79132.1 - 0.082 12.2 0.1 0.11 11.7 0.1 1.1 1 0 0 1 1 1 0 Exocyst complex subunit Sec15-like DUF4611 PF15387.1 EIE79134.1 - 0.91 9.7 10.7 0.21 11.7 0.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4611) Nop25 PF09805.4 EIE79134.1 - 1 9.4 9.6 3.5 7.7 0.9 2.1 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) GlutR_dimer PF00745.15 EIE79135.1 - 0.06 13.2 0.2 0.071 13.0 0.1 1.1 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, dimerisation domain RGS PF00615.14 EIE79136.1 - 4.7e-09 36.3 0.4 6.8e-09 35.8 0.3 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain PRESAN PF09687.5 EIE79136.1 - 0.1 12.6 3.4 0.26 11.3 0.1 2.6 1 1 2 3 3 3 0 Plasmodium RESA N-terminal Pyr_redox PF00070.22 EIE79137.1 - 4.4e-11 43.0 0.0 9.5e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EIE79137.1 - 9e-05 22.4 0.1 0.49 10.2 0.1 2.6 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EIE79137.1 - 0.0091 14.9 0.1 0.56 9.0 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EIE79137.1 - 0.033 14.2 0.0 0.85 9.6 0.0 2.1 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EIE79137.1 - 0.042 13.6 0.0 0.23 11.2 0.0 2.0 1 1 1 2 2 2 0 FAD-NAD(P)-binding PHR PF08005.7 EIE79137.1 - 0.042 14.0 0.0 0.073 13.2 0.0 1.3 1 0 0 1 1 1 0 PHR domain Lycopene_cycl PF05834.7 EIE79137.1 - 0.069 12.0 0.0 0.099 11.5 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.17 EIE79137.1 - 0.13 11.0 0.4 1.1 8.0 0.0 2.4 3 0 0 3 3 3 0 Glucose inhibited division protein A zf-CCCH PF00642.19 EIE79138.1 - 1.2e-12 47.1 14.8 4.2e-07 29.4 1.7 2.7 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 EIE79138.1 - 1.6e-06 27.8 0.0 2.6e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EIE79138.1 - 0.00013 21.5 0.0 0.00024 20.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CART PF06373.6 EIE79138.1 - 0.045 13.7 1.6 0.96 9.4 0.2 2.4 2 0 0 2 2 2 0 Cocaine and amphetamine regulated transcript protein (CART) RRM_6 PF14259.1 EIE79138.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF3493 PF11998.3 EIE79139.1 - 0.035 14.0 0.0 0.036 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3493) DUF3774 PF12609.3 EIE79139.1 - 0.42 11.4 2.1 6.6 7.6 0.5 2.1 2 0 0 2 2 2 0 Wound-induced protein UNC45-central PF11701.3 EIE79140.1 - 9.9e-15 54.5 2.4 9.9e-15 54.5 1.7 3.3 4 1 0 4 4 4 1 Myosin-binding striated muscle assembly central TPR_1 PF00515.23 EIE79140.1 - 0.00023 20.6 0.1 0.00056 19.4 0.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.12 EIE79140.1 - 0.00085 19.0 0.1 0.0028 17.4 0.1 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 EIE79140.1 - 0.0012 18.4 0.1 0.0051 16.4 0.1 2.1 2 0 0 2 2 2 1 TPR repeat TPR_14 PF13428.1 EIE79140.1 - 0.0025 18.3 0.0 0.013 16.1 0.0 2.3 1 0 0 1 1 1 1 Tetratricopeptide repeat HEAT_2 PF13646.1 EIE79140.1 - 0.0051 17.0 5.5 0.77 10.0 0.4 4.2 2 2 0 2 2 2 1 HEAT repeats Arm PF00514.18 EIE79140.1 - 0.012 15.4 0.8 0.49 10.2 0.0 3.5 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat TPR_8 PF13181.1 EIE79140.1 - 0.014 15.1 0.1 0.06 13.1 0.1 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_9 PF13371.1 EIE79140.1 - 0.018 14.8 0.1 0.064 13.1 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat HEAT PF02985.17 EIE79140.1 - 0.028 14.4 0.6 15 5.9 0.0 4.1 4 0 0 4 4 4 0 HEAT repeat Fis1_TPR_C PF14853.1 EIE79140.1 - 3.9 7.4 6.2 0.5 10.2 0.1 2.6 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat HLH PF00010.21 EIE79141.1 - 1.2e-13 50.5 1.3 1.2e-13 50.5 0.9 2.3 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain HALZ PF02183.13 EIE79141.1 - 0.37 10.5 4.5 0.31 10.7 2.0 1.8 2 0 0 2 2 2 0 Homeobox associated leucine zipper Cut8_N PF14482.1 EIE79141.1 - 1.3 9.1 9.1 0.21 11.6 1.8 2.4 2 0 0 2 2 2 0 Cut8 proteasome-binding domain Atg14 PF10186.4 EIE79141.1 - 3.4 6.5 14.7 3.8 6.3 9.6 1.6 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DEAD PF00270.24 EIE79142.1 - 3e-46 156.9 0.0 6.1e-45 152.7 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIE79142.1 - 1.8e-11 43.7 0.0 4.9e-11 42.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIE79142.1 - 0.0012 18.7 0.0 0.0049 16.7 0.0 2.0 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EIE79143.1 - 1.4e-11 44.0 0.2 3.2e-11 42.9 0.1 1.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Peptidase_M76 PF09768.4 EIE79144.1 - 9.4e-49 165.1 4.2 1.5e-31 109.1 0.1 2.1 1 1 1 2 2 2 2 Peptidase M76 family Peptidase_M13 PF01431.16 EIE79144.1 - 0.0061 15.7 0.3 0.0061 15.7 0.2 1.6 2 0 0 2 2 2 1 Peptidase family M13 Peptidase_M91 PF14891.1 EIE79144.1 - 0.1 12.6 1.2 0.29 11.1 0.7 1.9 1 1 0 1 1 1 0 Effector protein DUF678 PF05077.7 EIE79144.1 - 0.43 10.5 2.7 0.27 11.2 0.2 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF678) Zn-ribbon_8 PF09723.5 EIE79144.1 - 1.4 8.9 5.6 22 5.0 0.5 3.0 3 0 0 3 3 3 0 Zinc ribbon domain TB2_DP1_HVA22 PF03134.14 EIE79145.1 - 3.4e-34 116.4 5.9 4.4e-34 116.1 4.1 1.1 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Abhydrolase_3 PF07859.8 EIE79146.1 - 5.6e-55 186.1 0.0 8.1e-55 185.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EIE79146.1 - 2.4e-08 33.0 0.0 5.5e-08 31.8 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) COesterase PF00135.23 EIE79146.1 - 3.9e-08 32.4 0.1 5.7e-07 28.6 0.0 2.0 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 EIE79146.1 - 7.9e-05 22.4 0.0 0.00011 21.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EIE79146.1 - 0.00019 20.7 0.0 0.00059 19.1 0.0 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.2 EIE79146.1 - 0.0044 15.9 0.0 0.0071 15.2 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme AXE1 PF05448.7 EIE79146.1 - 0.031 12.7 0.0 0.05 12.1 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) mRNA_cap_enzyme PF01331.14 EIE79147.1 - 2.2e-13 50.3 0.0 2.9e-11 43.4 0.0 2.1 1 1 0 1 1 1 1 mRNA capping enzyme, catalytic domain Peptidase_M24 PF00557.19 EIE79148.1 - 5.6e-46 156.7 0.2 9e-46 156.0 0.1 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Leader_CPA1 PF08252.6 EIE79148.1 - 0.03 13.5 0.3 0.062 12.5 0.2 1.5 1 0 0 1 1 1 0 arg-2/CPA1 leader peptide Slu7 PF11708.3 EIE79149.1 - 1.7e-79 266.9 20.2 3.4e-79 265.9 14.0 1.4 1 0 0 1 1 1 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.1 EIE79149.1 - 0.31 10.7 3.1 0.15 11.7 0.5 1.7 2 0 0 2 2 2 0 Zinc knuckle CaM_binding PF07839.6 EIE79149.1 - 1.3 9.2 6.6 0.33 11.1 0.1 2.9 3 0 0 3 3 3 0 Plant calmodulin-binding domain SAP PF02037.22 EIE79150.1 - 5.2e-11 41.7 0.8 8.3e-11 41.1 0.5 1.3 1 0 0 1 1 1 1 SAP domain RPA_interact_N PF14766.1 EIE79150.1 - 0.12 11.9 0.7 0.38 10.2 0.2 2.1 2 0 0 2 2 2 0 Replication protein A interacting N-terminal TFIIA PF03153.8 EIE79150.1 - 0.51 10.1 21.7 0.63 9.8 15.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 EIE79150.1 - 0.52 8.4 40.2 0.63 8.2 27.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 BPL_LplA_LipB PF03099.14 EIE79151.1 - 0.00072 19.5 0.0 0.00072 19.5 0.0 1.0 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family SRF-TF PF00319.13 EIE79152.1 - 1.7e-22 78.4 0.0 2.7e-22 77.7 0.0 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) AAA PF00004.24 EIE79154.1 - 1.3e-46 158.0 0.0 1.7e-28 99.4 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 EIE79154.1 - 2.7e-29 101.0 0.1 1e-28 99.1 0.0 2.1 2 0 0 2 2 2 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.1 EIE79154.1 - 1e-08 35.4 0.3 2.1e-06 27.8 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain NACHT PF05729.7 EIE79154.1 - 5.9e-06 26.0 0.0 9.5e-05 22.1 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 EIE79154.1 - 0.00078 19.5 0.2 0.077 13.1 0.2 3.6 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EIE79154.1 - 0.0015 18.4 0.0 0.018 14.9 0.0 2.8 3 0 0 3 3 3 1 AAA domain Sigma54_activat PF00158.21 EIE79154.1 - 0.0063 15.9 0.0 0.025 14.0 0.0 2.0 2 0 0 2 2 2 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 EIE79154.1 - 0.011 15.8 0.0 0.054 13.5 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain NB-ARC PF00931.17 EIE79154.1 - 0.014 14.2 0.0 0.067 12.0 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain AAA_18 PF13238.1 EIE79154.1 - 0.015 15.5 0.0 0.051 13.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_35 PF14516.1 EIE79154.1 - 0.021 13.4 0.0 0.1 11.2 0.0 2.1 2 1 1 3 3 3 0 AAA-like domain AAA_5 PF07728.9 EIE79154.1 - 0.025 14.3 0.0 0.73 9.5 0.0 3.3 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) DUF815 PF05673.8 EIE79154.1 - 0.025 13.4 0.0 0.059 12.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TrwB_AAD_bind PF10412.4 EIE79154.1 - 0.035 12.7 0.7 0.087 11.4 0.1 1.8 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_17 PF13207.1 EIE79154.1 - 0.051 14.3 0.0 0.2 12.4 0.0 2.0 2 0 0 2 2 1 0 AAA domain ATP-synt_ab PF00006.20 EIE79154.1 - 0.065 12.7 0.0 0.18 11.2 0.0 1.7 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_29 PF13555.1 EIE79154.1 - 0.14 11.7 0.4 0.32 10.5 0.3 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Homeobox PF00046.24 EIE79155.1 - 1.3e-15 56.6 4.9 2.5e-15 55.8 3.4 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EIE79155.1 - 0.00024 20.7 1.3 0.00059 19.4 0.7 1.8 2 0 0 2 2 2 1 Homeobox KN domain CamS PF07537.6 EIE79155.1 - 0.07 12.1 1.8 0.097 11.6 1.3 1.1 1 0 0 1 1 1 0 CamS sex pheromone cAM373 precursor LIM PF00412.17 EIE79156.1 - 8.5e-18 64.1 32.9 6.6e-07 29.3 4.0 4.7 5 1 0 5 5 5 3 LIM domain zf-C4 PF00105.13 EIE79156.1 - 0.0067 16.6 4.8 0.0067 16.6 3.3 4.5 3 2 0 4 4 4 2 Zinc finger, C4 type (two domains) Vps39_2 PF10367.4 EIE79156.1 - 0.069 13.3 0.2 0.069 13.3 0.1 5.0 2 2 3 6 6 6 0 Vacuolar sorting protein 39 domain 2 Mut7-C PF01927.11 EIE79156.1 - 0.074 13.0 12.5 0.23 11.4 0.1 3.9 4 0 0 4 4 4 0 Mut7-C RNAse domain c-SKI_SMAD_bind PF08782.5 EIE79156.1 - 1.1 9.4 13.6 0.031 14.3 1.9 3.2 2 1 1 3 3 3 0 c-SKI Smad4 binding domain TerB-N PF13208.1 EIE79157.1 - 0.08 12.3 0.8 1.8 7.9 0.0 2.8 2 1 1 3 3 3 0 TerB-N TFIIA PF03153.8 EIE79158.1 - 1 9.1 14.4 1.2 8.9 10.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 EIE79158.1 - 1.7 6.8 29.9 1.9 6.6 20.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 bZIP_2 PF07716.10 EIE79159.1 - 4.5e-12 45.5 7.5 9e-12 44.6 5.2 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 EIE79159.1 - 0.00043 20.1 7.3 0.00043 20.1 5.1 1.7 2 0 0 2 2 2 1 bZIP transcription factor Adeno_PIX PF03955.9 EIE79159.1 - 0.062 13.8 0.2 0.062 13.8 0.2 1.7 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) Nsp1_C PF05064.8 EIE79159.1 - 0.29 10.7 6.3 1.2 8.8 0.7 2.3 2 0 0 2 2 2 0 Nsp1-like C-terminal region IncA PF04156.9 EIE79159.1 - 0.4 10.2 3.7 0.11 12.1 0.6 1.5 2 0 0 2 2 2 0 IncA protein XhlA PF10779.4 EIE79159.1 - 0.42 10.5 4.1 0.92 9.4 2.8 1.5 1 0 0 1 1 1 0 Haemolysin XhlA Fib_alpha PF08702.5 EIE79159.1 - 1.1 9.3 9.6 0.96 9.5 2.8 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Pkinase PF00069.20 EIE79161.1 - 4.4e-71 239.0 0.0 6.2e-71 238.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE79161.1 - 2.3e-40 138.3 0.0 3.2e-40 137.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE79161.1 - 0.0033 16.4 0.0 0.0056 15.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like DDE_3 PF13358.1 EIE79162.1 - 0.001 18.8 0.2 0.0027 17.4 0.1 1.9 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE79162.1 - 0.017 15.2 0.1 0.29 11.2 0.0 2.8 2 0 0 2 2 2 0 Transposase Vsr PF03852.10 EIE79162.1 - 0.044 13.4 0.0 0.14 11.7 0.0 1.9 1 0 0 1 1 1 0 DNA mismatch endonuclease Vsr Lipase_GDSL PF00657.17 EIE79163.1 - 3.7e-07 30.2 4.3 3.8e-06 26.8 3.0 2.1 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EIE79163.1 - 9.9e-06 25.7 0.0 1.9e-05 24.9 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Ribosomal_L13 PF00572.13 EIE79164.1 - 3e-25 88.7 0.0 5.1e-25 87.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L13 AAA_18 PF13238.1 EIE79165.1 - 5.1e-11 42.9 0.1 2.4e-09 37.6 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EIE79165.1 - 1.7e-09 38.5 0.1 5.4e-09 36.9 0.1 1.9 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 EIE79165.1 - 1.5e-08 34.4 0.0 2.9e-08 33.5 0.0 1.5 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.1 EIE79165.1 - 0.00013 21.8 0.0 0.00062 19.6 0.0 2.1 2 1 0 2 2 2 1 AAA domain DUF4264 PF14084.1 EIE79165.1 - 0.0032 16.8 0.4 0.0071 15.6 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF4264) CPT PF07931.7 EIE79165.1 - 0.011 15.3 0.0 0.019 14.6 0.0 1.5 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Zeta_toxin PF06414.7 EIE79165.1 - 0.023 13.8 0.0 0.049 12.7 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.1 EIE79165.1 - 0.028 14.3 0.0 0.078 12.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EIE79165.1 - 0.076 12.9 0.0 0.12 12.3 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 EIE79165.1 - 0.15 12.3 0.4 0.3 11.3 0.3 1.9 1 1 0 1 1 1 0 ABC transporter MFS_1 PF07690.11 EIE79166.1 - 3.4e-27 95.0 38.1 3.4e-27 95.0 26.4 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIE79166.1 - 6.5e-09 34.8 8.8 6.5e-09 34.8 6.1 3.8 2 2 2 4 4 4 2 Sugar (and other) transporter ATG22 PF11700.3 EIE79166.1 - 0.00056 18.5 25.3 0.0093 14.4 1.3 3.0 3 0 0 3 3 3 2 Vacuole effluxer Atg22 like FLILHELTA PF10306.4 EIE79166.1 - 0.028 14.4 0.0 0.098 12.7 0.0 1.9 1 0 0 1 1 1 0 Hypothetical protein FLILHELTA GWT1 PF06423.7 EIE79166.1 - 1.3 9.1 7.8 0.1 12.6 1.1 2.4 2 1 0 2 2 2 0 GWT1 PTPLA PF04387.9 EIE79167.1 - 1.4e-42 144.9 10.7 1.4e-42 144.9 7.5 1.5 2 0 0 2 2 2 1 Protein tyrosine phosphatase-like protein, PTPLA Rad51 PF08423.6 EIE79168.1 - 3.9e-100 334.0 0.1 5.2e-83 277.8 0.0 2.2 1 1 1 2 2 2 2 Rad51 RecA PF00154.16 EIE79168.1 - 1.6e-05 24.1 0.1 0.0017 17.4 0.0 2.1 1 1 1 2 2 2 2 recA bacterial DNA recombination protein AAA_25 PF13481.1 EIE79168.1 - 0.00012 21.5 0.0 0.00028 20.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain HHH_5 PF14520.1 EIE79168.1 - 0.00028 20.9 0.2 0.00065 19.8 0.1 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain RNA_pol_A_CTD PF03118.10 EIE79168.1 - 0.027 13.8 0.6 0.1 12.0 0.4 1.9 1 1 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain PQ-loop PF04193.9 EIE79169.1 - 1.7e-38 129.9 11.9 1.4e-19 69.3 1.0 2.6 2 0 0 2 2 2 2 PQ loop repeat Herpes_capsid PF06112.6 EIE79171.1 - 1.9 8.4 7.4 1.7 8.6 3.2 1.9 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein PAS_3 PF08447.6 EIE79173.1 - 2.1e-13 50.1 0.0 4.2e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS PF00989.19 EIE79173.1 - 7.1e-09 35.4 0.0 1.4e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_11 PF14598.1 EIE79173.1 - 1.3e-07 31.5 0.1 2.4e-07 30.6 0.1 1.4 1 0 0 1 1 1 1 PAS domain PAS_9 PF13426.1 EIE79173.1 - 2.9e-05 24.3 0.0 6.2e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.5 EIE79173.1 - 0.00032 20.6 0.0 0.00058 19.8 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.1 EIE79173.1 - 0.0033 17.2 0.0 0.0071 16.1 0.0 1.5 1 0 0 1 1 1 1 PAS domain DUF972 PF06156.8 EIE79173.1 - 0.58 10.5 4.2 0.24 11.7 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Git3_C PF11970.3 EIE79174.1 - 0.15 11.8 1.0 3.6 7.4 0.1 2.2 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term Lipase_GDSL PF00657.17 EIE79175.1 - 1e-06 28.7 0.1 2.3e-06 27.6 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EIE79175.1 - 0.069 13.2 0.0 0.17 12.0 0.0 1.6 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Glyco_hydro_16 PF00722.16 EIE79176.1 - 4.6e-08 32.5 0.0 7.2e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Ribonuclease PF00545.15 EIE79177.1 - 0.092 12.8 0.2 0.49 10.4 0.0 2.2 2 0 0 2 2 2 0 ribonuclease Na_H_Exchanger PF00999.16 EIE79178.1 - 8.3e-34 116.7 39.7 6.4e-33 113.8 27.5 2.1 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family DUF2746 PF10874.3 EIE79178.1 - 0.091 12.9 0.5 0.2 11.8 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) Pkinase PF00069.20 EIE79181.1 - 6.3e-52 176.2 0.0 8.2e-52 175.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE79181.1 - 1.7e-23 82.9 0.0 2.3e-23 82.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EIE79181.1 - 4e-05 22.5 1.1 7.8e-05 21.6 0.1 1.7 1 1 1 2 2 2 1 Poxvirus serine/threonine protein kinase Kinase-like PF14531.1 EIE79181.1 - 0.016 14.2 0.0 0.034 13.0 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 EIE79181.1 - 0.096 11.7 0.1 0.18 10.8 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Endotoxin_N PF03945.9 EIE79182.1 - 0.27 10.6 2.6 0.28 10.5 0.5 1.8 2 0 0 2 2 2 0 delta endotoxin, N-terminal domain YyzF PF14116.1 EIE79182.1 - 0.66 9.9 5.1 1.7 8.6 0.2 3.1 3 0 0 3 3 3 0 YyzF-like protein CN_hydrolase PF00795.17 EIE79183.1 - 1.2e-28 99.7 0.0 2.3e-28 98.8 0.0 1.5 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase EF-hand_1 PF00036.27 EIE79184.1 - 2.6e-17 60.7 2.8 3.8e-06 25.7 0.0 4.0 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.1 EIE79184.1 - 1.2e-15 57.3 5.6 9.7e-06 25.6 0.3 3.5 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.1 EIE79184.1 - 2.8e-15 55.6 1.7 9.2e-06 25.1 0.0 3.7 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 EIE79184.1 - 1.2e-14 52.7 2.4 8.1e-06 25.3 0.1 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.1 EIE79184.1 - 3.6e-12 45.0 0.8 8.8e-05 21.6 0.0 3.9 3 0 0 3 3 3 2 EF hand ZZ PF00569.12 EIE79184.1 - 2.8e-09 36.3 9.4 5.1e-09 35.5 6.5 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Caleosin PF05042.8 EIE79184.1 - 0.0037 16.8 0.1 0.027 14.0 0.0 2.2 1 1 1 2 2 2 1 Caleosin related protein HCaRG PF07258.9 EIE79184.1 - 0.01 15.3 0.3 0.17 11.4 0.0 2.7 3 0 0 3 3 3 0 HCaRG protein SPARC_Ca_bdg PF10591.4 EIE79184.1 - 0.17 11.9 4.7 0.82 9.7 0.0 3.3 3 2 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region DUF3752 PF12572.3 EIE79185.1 - 3.2e-27 95.5 13.2 3.2e-27 95.5 9.2 2.3 1 1 0 2 2 2 1 Protein of unknown function (DUF3752) YycC PF14174.1 EIE79185.1 - 0.0065 16.1 12.7 2.4 7.8 0.1 4.8 5 0 0 5 5 5 4 YycC-like protein LSM PF01423.17 EIE79186.1 - 8e-17 60.5 0.1 1e-16 60.1 0.1 1.2 1 0 0 1 1 1 1 LSM domain Acetyltransf_1 PF00583.19 EIE79187.1 - 3.1e-12 46.3 0.0 4.9e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EIE79187.1 - 2.3e-06 27.6 0.1 4.7e-06 26.6 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EIE79187.1 - 5.8e-06 25.9 0.0 1.4e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 EIE79187.1 - 4.3e-05 23.3 0.1 7.2e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EIE79187.1 - 0.00011 22.3 0.0 0.00017 21.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EIE79187.1 - 0.00063 19.6 0.0 0.0009 19.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EIE79187.1 - 0.00087 19.2 0.0 0.0012 18.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain WW PF00397.21 EIE79188.1 - 5e-05 23.0 8.6 0.00016 21.4 6.0 2.0 1 0 0 1 1 1 1 WW domain DUF1719 PF08224.6 EIE79188.1 - 0.023 13.8 0.0 0.04 13.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1719) zf-H2C2_2 PF13465.1 EIE79189.1 - 9.4e-18 63.5 19.4 3.8e-09 36.3 0.4 4.4 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.21 EIE79189.1 - 5.6e-15 54.6 27.0 5.6e-06 26.3 1.7 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIE79189.1 - 3.1e-10 39.6 26.1 0.00045 20.3 1.7 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EIE79189.1 - 3.2e-06 27.1 12.8 0.048 13.8 0.1 3.7 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EIE79189.1 - 4.8e-05 23.1 15.3 0.14 12.1 0.3 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger TPR_MLP1_2 PF07926.7 EIE79189.1 - 0.0014 18.3 5.5 0.0033 17.1 3.8 1.5 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein zf-met PF12874.2 EIE79189.1 - 0.0025 17.9 1.2 0.0025 17.9 0.8 3.7 3 0 0 3 3 3 2 Zinc-finger of C2H2 type TSC22 PF01166.13 EIE79189.1 - 0.015 15.2 5.4 0.13 12.2 0.4 2.9 1 1 1 2 2 2 0 TSC-22/dip/bun family zf-H2C2_5 PF13909.1 EIE79189.1 - 0.017 15.3 2.8 0.017 15.3 1.9 3.4 3 1 0 3 3 3 0 C2H2-type zinc-finger domain Zn-ribbon_8 PF09723.5 EIE79189.1 - 0.038 13.9 7.5 7.7 6.5 0.3 3.4 2 1 2 4 4 4 0 Zinc ribbon domain RRN7 PF11781.3 EIE79189.1 - 0.042 13.3 4.8 3.2 7.3 0.1 3.2 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 bZIP_1 PF00170.16 EIE79189.1 - 0.042 13.7 3.8 0.72 9.8 0.4 2.6 1 1 1 2 2 2 0 bZIP transcription factor GAGA PF09237.6 EIE79189.1 - 0.084 12.4 10.2 1.8 8.2 2.6 2.7 1 1 1 2 2 2 0 GAGA factor DUF904 PF06005.7 EIE79189.1 - 0.095 13.0 4.2 0.36 11.1 2.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF904) C1_4 PF07975.7 EIE79189.1 - 0.13 12.2 13.7 0.46 10.5 5.1 3.3 1 1 2 3 3 3 0 TFIIH C1-like domain HALZ PF02183.13 EIE79189.1 - 0.19 11.4 5.8 2.3 8.0 2.2 2.9 1 1 1 2 2 2 0 Homeobox associated leucine zipper zf-C2H2_2 PF12756.2 EIE79189.1 - 0.45 10.6 15.9 0.79 9.8 0.1 3.7 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) DivIC PF04977.10 EIE79189.1 - 0.84 9.1 6.3 1.3 8.5 0.5 2.4 1 1 1 2 2 2 0 Septum formation initiator C1_3 PF07649.7 EIE79189.1 - 1.2 9.2 5.1 41 4.3 0.1 3.3 3 0 0 3 3 3 0 C1-like domain Elf1 PF05129.8 EIE79189.1 - 1.2 8.8 6.9 4.1 7.1 1.2 2.6 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like Zn_Tnp_IS1595 PF12760.2 EIE79189.1 - 1.7 8.4 9.0 0.34 10.7 1.5 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Pox_A_type_inc PF04508.7 EIE79189.1 - 3.7 7.5 6.2 4.9 7.1 0.3 2.8 3 0 0 3 3 2 0 Viral A-type inclusion protein repeat TFIIS_C PF01096.13 EIE79189.1 - 3.8 7.2 7.5 29 4.3 0.1 3.3 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) HypA PF01155.14 EIE79189.1 - 5 6.8 6.3 4.9 6.8 1.8 2.3 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family DZR PF12773.2 EIE79189.1 - 8.1 6.3 8.9 32 4.4 0.2 2.6 1 1 1 2 2 2 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.6 EIE79189.1 - 9.1 6.0 8.0 13 5.5 2.3 2.8 2 1 0 2 2 2 0 Putative transposase DNA-binding domain zinc_ribbon_4 PF13717.1 EIE79189.1 - 9.5 6.0 8.6 22 4.8 0.3 3.3 3 0 0 3 3 3 0 zinc-ribbon domain KilA-N PF04383.8 EIE79190.1 - 0.014 15.0 0.1 0.091 12.3 0.1 2.5 1 1 0 1 1 1 0 KilA-N domain DUF3880 PF12996.2 EIE79191.1 - 0.068 13.0 0.1 0.22 11.4 0.1 1.9 1 0 0 1 1 1 0 DUF based on E. rectale Gene description (DUF3880) DUF1048 PF06304.6 EIE79191.1 - 0.078 13.2 0.1 0.15 12.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1048) DUF1043 PF06295.7 EIE79191.1 - 0.13 11.8 0.3 0.28 10.8 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) UCR_14kD PF02271.11 EIE79192.1 - 1.3e-38 131.0 0.7 1.5e-38 130.8 0.5 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit She9_MDM33 PF05546.6 EIE79192.1 - 0.0026 17.3 0.0 0.0028 17.2 0.0 1.0 1 0 0 1 1 1 1 She9 / Mdm33 family DLIC PF05783.6 EIE79193.1 - 1.8e-52 178.5 11.2 7e-42 143.6 0.0 3.0 1 1 1 2 2 2 2 Dynein light intermediate chain (DLIC) Far-17a_AIG1 PF04750.9 EIE79194.1 - 9.4e-40 135.9 13.2 1e-39 135.7 9.1 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein CPDase PF07823.6 EIE79196.1 - 0.12 11.7 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 Cyclic phosphodiesterase-like protein 2Fe-2S_thioredx PF01257.14 EIE79198.1 - 2.1e-58 196.0 0.1 2.8e-58 195.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin RhoGAP PF00620.22 EIE79200.1 - 3.9e-49 166.1 0.0 1.2e-48 164.5 0.0 1.9 1 0 0 1 1 1 1 RhoGAP domain RasGEF_N PF00618.15 EIE79200.1 - 1.7e-22 79.4 9.1 1.1e-13 51.1 2.4 4.6 4 0 0 4 4 4 2 RasGEF N-terminal motif RasGEF PF00617.14 EIE79200.1 - 2.5e-21 76.2 0.3 5.2e-16 58.9 0.0 3.3 2 1 0 2 2 2 2 RasGEF domain PH_9 PF15410.1 EIE79200.1 - 9.4e-13 48.3 0.2 2.9e-12 46.7 0.1 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EIE79200.1 - 1.9e-05 24.7 0.0 6.2e-05 23.1 0.0 1.9 1 0 0 1 1 1 1 PH domain Pribosyl_synth PF14572.1 EIE79201.1 - 2.5e-42 144.6 1.4 5.3e-41 140.3 1.0 2.1 1 1 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 EIE79201.1 - 2.3e-30 104.6 0.3 1.4e-25 89.3 0.1 3.4 2 1 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 EIE79201.1 - 7.1e-05 22.5 0.5 0.00099 18.8 0.3 2.6 2 1 0 2 2 2 1 Phosphoribosyl transferase domain Oxidored_FMN PF00724.15 EIE79201.1 - 0.12 11.3 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 NADH:flavin oxidoreductase / NADH oxidase family Sel1 PF08238.7 EIE79202.1 - 4.4e-44 147.9 27.7 8.1e-08 32.6 0.0 8.3 8 0 0 8 8 8 7 Sel1 repeat TPR_11 PF13414.1 EIE79202.1 - 5.1e-05 22.8 14.6 0.001 18.6 0.0 4.5 2 2 3 5 5 5 3 TPR repeat TPR_12 PF13424.1 EIE79202.1 - 0.0062 16.4 6.0 0.052 13.4 0.1 4.0 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 EIE79202.1 - 0.015 15.0 1.0 22 5.1 0.2 4.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Thg1C PF14413.1 EIE79202.1 - 0.083 12.5 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 Thg1 C terminal domain TPR_6 PF13174.1 EIE79202.1 - 1.9 9.1 15.1 3.1 8.4 0.0 5.7 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_16 PF13432.1 EIE79202.1 - 3.9 8.2 14.1 14 6.5 0.3 5.0 4 2 2 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.1 EIE79202.1 - 7.4 6.9 12.7 6.3 7.2 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 EIE79202.1 - 8 6.2 11.1 21 4.9 0.7 5.5 5 1 0 5 5 5 0 Tetratricopeptide repeat S1 PF00575.18 EIE79203.1 - 2.9e-47 158.6 10.6 1.2e-11 44.5 0.1 7.6 7 0 0 7 7 7 7 S1 RNA binding domain Adaptin_binding PF10199.4 EIE79203.1 - 0.19 12.0 0.1 0.19 12.0 0.0 3.3 3 0 0 3 3 3 0 Alpha and gamma adaptin binding protein p34 TFIIA PF03153.8 EIE79203.1 - 2.9 7.6 34.4 5.9 6.6 20.6 2.5 2 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit WRKY PF03106.10 EIE79204.1 - 8.1e-06 25.5 4.7 1.6e-05 24.6 3.2 1.5 1 0 0 1 1 1 1 WRKY DNA -binding domain FLYWCH PF04500.11 EIE79204.1 - 0.018 14.9 0.6 0.033 14.0 0.4 1.5 1 0 0 1 1 1 0 FLYWCH zinc finger domain Zn_ribbon_recom PF13408.1 EIE79204.1 - 0.61 10.3 3.7 1.5 9.1 2.6 1.7 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain Ribosomal_L13e PF01294.13 EIE79206.1 - 1.8e-79 265.3 7.6 2.6e-79 264.8 5.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e DUF3959 PF13105.1 EIE79206.1 - 0.14 11.4 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) BPD_transp_1 PF00528.17 EIE79208.1 - 0.024 14.1 0.7 0.024 14.1 0.5 1.8 3 0 0 3 3 3 0 Binding-protein-dependent transport system inner membrane component Rick_17kDa_Anti PF05433.10 EIE79209.1 - 0.011 15.3 9.3 0.06 13.0 2.5 2.2 2 0 0 2 2 2 0 Glycine zipper 2TM domain Gly-zipper_YMGG PF13441.1 EIE79209.1 - 0.11 12.0 11.7 0.65 9.5 3.3 2.3 2 0 0 2 2 2 0 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.1 EIE79209.1 - 0.12 12.0 11.0 0.32 10.6 3.6 2.4 2 0 0 2 2 2 0 Glycine zipper Mitofilin PF09731.4 EIE79209.1 - 1.2 7.6 13.2 1.5 7.3 9.2 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Ribosomal_L15e PF00827.12 EIE79210.1 - 7.4e-90 299.6 12.3 8.5e-90 299.4 8.5 1.0 1 0 0 1 1 1 1 Ribosomal L15 Ribosomal_L22 PF00237.14 EIE79211.1 - 5.9e-34 116.1 0.1 8.3e-34 115.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e DUF3808 PF10300.4 EIE79212.1 - 7.7e-65 219.2 5.6 1.6e-64 218.2 3.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_2 PF07719.12 EIE79212.1 - 0.00029 20.5 0.1 1.7 8.7 0.2 4.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 EIE79212.1 - 0.013 15.3 0.3 0.28 11.1 0.2 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 EIE79212.1 - 0.076 12.6 6.3 1.7 8.3 0.3 4.5 4 2 2 6 6 6 0 TPR repeat TPR_6 PF13174.1 EIE79212.1 - 0.35 11.4 1.8 1.4e+02 3.2 0.1 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat ATP_synt_H PF05493.8 EIE79213.1 - 1e-22 79.9 4.9 1.2e-22 79.7 3.4 1.0 1 0 0 1 1 1 1 ATP synthase subunit H ARL6IP6 PF15062.1 EIE79213.1 - 0.044 13.6 0.0 0.056 13.3 0.0 1.2 1 0 0 1 1 1 0 Haemopoietic lineage transmembrane helix YibE_F PF07907.6 EIE79213.1 - 0.23 10.6 2.6 0.26 10.4 1.8 1.0 1 0 0 1 1 1 0 YibE/F-like protein WD40 PF00400.27 EIE79214.1 - 1.3e-07 31.2 0.8 3.8 7.5 0.0 5.6 7 0 0 7 7 7 3 WD domain, G-beta repeat DUF2433 PF10360.4 EIE79214.1 - 0.06 13.6 0.2 0.15 12.3 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2433) PH PF00169.24 EIE79215.1 - 8.1e-10 38.8 4.5 3.5e-08 33.6 0.2 3.0 3 0 0 3 3 3 2 PH domain CENP-B_dimeris PF09026.5 EIE79215.1 - 0.73 10.1 17.3 8.1 6.7 8.4 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain IBN_N PF03810.14 EIE79217.1 - 7.8e-16 57.7 0.4 1.2e-14 53.9 0.1 3.0 3 0 0 3 3 3 1 Importin-beta N-terminal domain Cse1 PF08506.5 EIE79217.1 - 5.9e-12 44.8 0.0 1.7e-09 36.7 0.0 2.5 2 0 0 2 2 2 2 Cse1 Xpo1 PF08389.7 EIE79217.1 - 0.0025 17.7 0.1 0.0025 17.7 0.1 3.9 4 1 1 5 5 5 1 Exportin 1-like protein RIX1 PF08167.7 EIE79217.1 - 0.0036 16.9 6.3 0.35 10.5 0.1 4.8 4 2 0 4 4 4 1 rRNA processing/ribosome biogenesis Upf2 PF04050.9 EIE79217.1 - 5.7 6.6 9.4 11 5.7 6.5 1.4 1 0 0 1 1 1 0 Up-frameshift suppressor 2 PLDc_2 PF13091.1 EIE79218.1 - 9.5e-13 48.0 0.1 8e-09 35.3 0.0 3.3 3 0 0 3 3 3 2 PLD-like domain PLDc PF00614.17 EIE79218.1 - 5.9e-12 44.9 0.2 5.2e-06 26.0 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PX PF00787.19 EIE79218.1 - 2.8e-07 30.3 1.9 3.1e-06 26.9 0.2 3.4 2 1 0 2 2 2 1 PX domain PH PF00169.24 EIE79218.1 - 0.014 15.5 0.2 0.053 13.7 0.1 2.0 1 0 0 1 1 1 0 PH domain zf-H2C2 PF09337.5 EIE79219.1 - 0.0021 17.4 0.1 0.0038 16.6 0.0 1.4 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger PIP49_N PF14875.1 EIE79219.1 - 0.025 14.2 0.5 0.047 13.3 0.3 1.4 1 0 0 1 1 1 0 N-term cysteine-rich ER, FAM69 B56 PF01603.15 EIE79220.1 - 2.6e-140 467.6 5.5 3.4e-140 467.2 3.8 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) GCOM2 PF15328.1 EIE79220.1 - 0.03 14.0 1.6 0.046 13.4 1.1 1.1 1 0 0 1 1 1 0 Putative GRINL1B complex locus protein 2 GCD14 PF08704.5 EIE79221.1 - 6.2e-19 68.4 0.0 1.7e-18 67.0 0.0 1.6 1 1 1 2 2 2 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_18 PF12847.2 EIE79221.1 - 4.5e-07 30.4 0.0 7e-07 29.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EIE79221.1 - 5.7e-07 29.2 0.0 7.3e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 EIE79221.1 - 5.8e-06 26.3 0.0 1e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIE79221.1 - 4.3e-05 23.1 0.0 6.4e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 EIE79221.1 - 4.5e-05 24.2 0.0 7.8e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 EIE79221.1 - 8.4e-05 21.7 0.0 0.00012 21.1 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase CMAS PF02353.15 EIE79221.1 - 0.00077 18.6 0.0 0.0012 17.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 EIE79221.1 - 0.0011 18.6 0.0 0.0018 18.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain GCD14_N PF14801.1 EIE79221.1 - 0.0038 16.7 0.0 0.0069 15.9 0.0 1.4 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit N-term MTS PF05175.9 EIE79221.1 - 0.0062 15.9 0.0 0.0093 15.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain RrnaAD PF00398.15 EIE79221.1 - 0.015 14.3 0.0 0.022 13.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_32 PF13679.1 EIE79221.1 - 0.022 14.4 0.0 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 EIE79221.1 - 0.029 14.7 0.0 0.053 13.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 EIE79221.1 - 0.033 14.6 0.0 0.07 13.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain LCM PF04072.9 EIE79222.1 - 8.1e-10 38.5 0.0 1e-09 38.2 0.0 1.1 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase YebO PF13974.1 EIE79223.1 - 0.0042 16.8 0.0 0.015 15.1 0.0 1.9 1 1 1 2 2 2 1 YebO-like protein BNIP3 PF06553.7 EIE79223.1 - 0.0069 15.7 8.1 0.0081 15.5 5.6 1.1 1 0 0 1 1 1 1 BNIP3 FANCI_S3 PF14677.1 EIE79223.1 - 0.022 14.1 2.3 0.031 13.6 1.6 1.2 1 0 0 1 1 1 0 FANCI solenoid 3 DUF1993 PF09351.5 EIE79223.1 - 0.05 13.5 0.3 0.05 13.5 0.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1993) DUF1779 PF08680.5 EIE79223.1 - 0.051 13.4 1.5 0.065 13.0 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1779) SPT16 PF08644.6 EIE79223.1 - 0.13 12.0 3.0 0.068 13.0 0.8 1.5 1 1 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) DUF106 PF01956.11 EIE79223.1 - 1.3 8.5 5.2 0.28 10.6 1.0 1.8 1 1 1 2 2 2 0 Integral membrane protein DUF106 RRM_1 PF00076.17 EIE79224.1 - 3.3e-10 39.4 0.0 6.8e-10 38.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE79224.1 - 1.1e-09 38.1 0.0 2.1e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE79224.1 - 5e-07 29.4 0.0 9.2e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Histone PF00125.19 EIE79225.1 - 1.4e-31 108.4 0.4 2.1e-31 107.8 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EIE79225.1 - 1.2e-05 25.3 0.0 1.8e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EIE79225.1 - 0.0061 16.6 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 EIE79225.1 - 0.014 14.6 1.1 0.023 13.9 0.8 1.5 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 EIE79225.1 - 0.019 14.6 0.1 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated RVT_1 PF00078.22 EIE79226.1 - 0.00034 20.0 0.0 0.00041 19.7 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PHD_2 PF13831.1 EIE79226.1 - 0.45 9.8 3.1 1 8.7 2.2 1.6 1 1 0 1 1 1 0 PHD-finger Rrn6 PF10214.4 EIE79229.1 - 0.073 11.1 0.1 0.084 10.9 0.1 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF2146 PF10220.4 EIE79229.1 - 0.12 10.2 0.3 0.17 9.8 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) HTH_Tnp_Tc3_2 PF01498.13 EIE79231.1 - 4e-10 39.5 3.2 1.8e-09 37.5 0.9 2.2 2 0 0 2 2 2 1 Transposase HTH_11 PF08279.7 EIE79231.1 - 0.00019 20.9 0.0 0.0005 19.6 0.0 1.6 1 0 0 1 1 1 1 HTH domain HTH_23 PF13384.1 EIE79231.1 - 0.00024 20.6 0.1 0.00059 19.3 0.0 1.6 2 0 0 2 2 1 1 Homeodomain-like domain HTH_IclR PF09339.5 EIE79231.1 - 0.00032 20.2 0.0 0.00069 19.1 0.0 1.6 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_7 PF02796.10 EIE79231.1 - 0.00044 20.0 0.3 0.012 15.5 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_32 PF13565.1 EIE79231.1 - 0.00075 20.2 1.1 0.9 10.3 0.1 2.5 2 1 0 2 2 2 2 Homeodomain-like domain HTH_38 PF13936.1 EIE79231.1 - 0.0016 17.9 0.0 0.0035 16.8 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.1 EIE79231.1 - 0.0034 17.5 0.2 0.034 14.3 0.0 2.0 2 0 0 2 2 2 1 Winged helix-turn helix Sigma70_r4_2 PF08281.7 EIE79231.1 - 0.0047 16.3 0.0 0.0091 15.4 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_36 PF13730.1 EIE79231.1 - 0.0083 16.2 0.0 0.1 12.7 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_24 PF13412.1 EIE79231.1 - 0.011 15.1 0.0 0.024 14.0 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Sigma70_r4 PF04545.11 EIE79231.1 - 0.013 14.8 0.0 0.025 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_AsnC-type PF13404.1 EIE79231.1 - 0.017 14.6 0.0 0.03 13.8 0.0 1.4 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_17 PF12728.2 EIE79231.1 - 0.021 15.0 0.0 0.039 14.1 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain GerE PF00196.14 EIE79231.1 - 0.023 14.0 0.0 0.045 13.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family UPF0122 PF04297.9 EIE79231.1 - 0.029 14.3 0.1 0.053 13.5 0.0 1.4 1 0 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like Terminase_5 PF06056.7 EIE79231.1 - 0.042 13.4 0.0 0.086 12.4 0.0 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) HTH_Tnp_4 PF13613.1 EIE79231.1 - 0.054 13.0 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_6 PF01418.12 EIE79231.1 - 0.069 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family HTH_Crp_2 PF13545.1 EIE79231.1 - 0.074 12.8 0.0 0.23 11.2 0.0 1.7 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain Trp_repressor PF01371.14 EIE79231.1 - 0.075 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Trp repressor protein HTH_28 PF13518.1 EIE79231.1 - 0.1 12.6 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain DUF603 PF04645.7 EIE79231.1 - 0.1 12.5 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF603 HTH_22 PF13309.1 EIE79231.1 - 0.11 12.3 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 HTH domain MarR_2 PF12802.2 EIE79231.1 - 0.11 12.1 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 MarR family DUF658 PF04936.7 EIE79231.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF658) HTH_31 PF13560.1 EIE79231.1 - 0.13 12.5 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain DDE_3 PF13358.1 EIE79232.1 - 1.2e-23 83.4 0.0 6.8e-16 58.3 0.0 2.6 1 1 1 2 2 2 2 DDE superfamily endonuclease HTH_29 PF13551.1 EIE79232.1 - 6.9e-06 26.1 0.0 1.4e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.1 EIE79232.1 - 0.0091 16.7 0.1 0.092 13.5 0.0 2.7 4 0 0 4 4 4 1 Homeodomain-like domain HTH_23 PF13384.1 EIE79232.1 - 0.019 14.6 0.0 0.056 13.1 0.0 1.8 2 0 0 2 2 2 0 Homeodomain-like domain Sigma70_r4_2 PF08281.7 EIE79232.1 - 0.026 13.9 0.1 0.076 12.4 0.0 1.7 2 0 0 2 2 2 0 Sigma-70, region 4 OrfB_IS605 PF01385.14 EIE79232.1 - 0.035 13.5 0.0 0.059 12.7 0.0 1.3 1 0 0 1 1 1 0 Probable transposase RVT_1 PF00078.22 EIE79234.1 - 0.00034 20.0 0.0 0.00041 19.7 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PHD_2 PF13831.1 EIE79234.1 - 0.45 9.8 3.1 1 8.7 2.2 1.6 1 1 0 1 1 1 0 PHD-finger UQ_con PF00179.21 EIE79235.1 - 2.7e-47 159.7 0.0 3.1e-47 159.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EIE79235.1 - 2.2e-05 24.2 0.0 3e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 EIE79235.1 - 0.017 14.7 0.1 0.033 13.8 0.0 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.17 EIE79235.1 - 0.063 13.1 0.1 0.071 13.0 0.0 1.4 1 1 0 1 1 1 0 RWD domain BATS PF06968.8 EIE79238.1 - 4.1e-27 93.8 0.0 1.2e-26 92.4 0.0 1.8 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 EIE79238.1 - 1.4e-15 57.8 0.1 2.3e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Aminotran_3 PF00202.16 EIE79239.1 - 2.9e-43 148.0 0.0 2.2e-24 85.9 0.0 2.3 2 0 0 2 2 2 2 Aminotransferase class-III AAA_26 PF13500.1 EIE79239.1 - 5.2e-16 58.8 0.0 1e-15 57.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain Acatn PF13000.2 EIE79240.1 - 3.7e-154 514.2 30.0 3.3e-80 270.1 10.7 3.2 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 DUF4446 PF14584.1 EIE79241.1 - 0.13 12.0 0.3 0.2 11.4 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4446) zf-RING_2 PF13639.1 EIE79241.1 - 0.14 11.9 0.1 0.23 11.3 0.1 1.3 1 0 0 1 1 1 0 Ring finger domain NAD_binding_4 PF07993.7 EIE79242.1 - 4.9e-45 153.4 0.0 7.6e-45 152.7 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EIE79242.1 - 5.4e-08 32.5 0.0 1.8e-07 30.8 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Acyltransferase PF01553.16 EIE79242.1 - 2e-05 24.0 0.0 5e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase 3Beta_HSD PF01073.14 EIE79242.1 - 2.4e-05 23.2 0.3 0.00063 18.5 0.2 2.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polyketide_cyc2 PF10604.4 EIE79243.1 - 0.0028 17.8 0.0 0.0035 17.5 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.15 EIE79243.1 - 0.067 13.1 0.5 0.16 11.9 0.2 1.7 1 1 1 2 2 2 0 Polyketide cyclase / dehydrase and lipid transport DUF2890 PF11081.3 EIE79243.1 - 8.5 6.3 8.6 4.9 7.1 1.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) Methyltransf_25 PF13649.1 EIE79244.1 - 1.3e-05 25.4 0.0 2.4e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIE79244.1 - 3.3e-05 23.5 0.2 0.00022 20.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Nol1_Nop2_Fmu PF01189.12 EIE79244.1 - 3.6e-05 23.2 0.0 4.5e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 NOL1/NOP2/sun family Methyltransf_18 PF12847.2 EIE79244.1 - 6.8e-05 23.4 0.0 0.00017 22.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIE79244.1 - 0.0025 17.8 0.0 0.0054 16.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EIE79244.1 - 0.015 14.8 0.0 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.7 EIE79244.1 - 0.017 15.5 0.1 0.17 12.3 0.0 2.4 3 0 0 3 3 3 0 Methyltransferase domain FtsJ PF01728.14 EIE79244.1 - 0.033 14.1 0.1 0.048 13.6 0.1 1.6 1 1 0 1 1 1 0 FtsJ-like methyltransferase AA_permease_N PF08403.5 EIE79244.1 - 0.074 12.3 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Amino acid permease N-terminal MTS PF05175.9 EIE79244.1 - 0.1 11.9 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Pik1 PF11522.3 EIE79245.1 - 6e-12 45.1 0.0 1.5e-11 43.8 0.0 1.7 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 SH3_9 PF14604.1 EIE79246.1 - 9.7e-11 41.0 0.0 1.7e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EIE79246.1 - 1.3e-09 37.2 0.1 2.4e-09 36.4 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EIE79246.1 - 7.1e-05 22.2 0.0 0.00014 21.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Ketoacyl-synt_C PF02801.17 EIE79246.1 - 0.0052 16.6 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain FCH PF00611.18 EIE79247.1 - 8.1e-05 22.7 0.3 0.18 12.0 0.0 2.3 2 0 0 2 2 2 2 Fes/CIP4, and EFC/F-BAR homology domain BAR PF03114.13 EIE79247.1 - 0.056 12.9 0.1 0.07 12.6 0.1 1.1 1 0 0 1 1 1 0 BAR domain PHD PF00628.24 EIE79249.1 - 4.9e-11 42.1 10.5 7.1e-11 41.6 7.3 1.2 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 EIE79249.1 - 0.046 13.8 8.0 0.14 12.2 5.4 1.8 1 1 1 2 2 2 0 PHD-like zinc-binding domain C1_1 PF00130.17 EIE79249.1 - 0.1 12.3 7.1 0.14 11.8 2.2 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Prim_Zn_Ribbon PF08273.7 EIE79249.1 - 1.9 8.6 12.5 11 6.2 8.6 2.2 1 1 0 1 1 1 0 Zinc-binding domain of primase-helicase Ssu72 PF04722.8 EIE79250.1 - 4.5e-56 189.2 0.1 4.8e-56 189.1 0.1 1.0 1 0 0 1 1 1 1 Ssu72-like protein G_glu_transpept PF01019.16 EIE79250.1 - 0.067 11.6 0.0 0.077 11.4 0.0 1.1 1 0 0 1 1 1 0 Gamma-glutamyltranspeptidase MF_alpha_N PF05436.6 EIE79251.1 - 0.097 12.3 0.1 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus DEAD PF00270.24 EIE79252.1 - 1.1e-47 161.7 0.0 1.9e-47 160.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIE79252.1 - 4.3e-28 96.9 0.0 1.1e-27 95.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIE79252.1 - 3.1e-06 27.1 0.0 1.7e-05 24.7 0.0 2.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 EIE79253.1 - 3.1e-46 157.4 4.2 4.3e-46 157.0 2.9 1.1 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.24 EIE79253.1 - 1e-06 28.3 0.1 1.3e-06 27.9 0.1 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase NST1 PF13945.1 EIE79253.1 - 0.032 14.3 3.1 0.049 13.7 2.2 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator HLH PF00010.21 EIE79256.1 - 2.3e-18 65.6 0.5 7.1e-18 64.0 0.4 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SUI1 PF01253.17 EIE79257.1 - 2.3e-27 94.6 0.8 2.8e-27 94.3 0.5 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 His_Phos_2 PF00328.17 EIE79258.1 - 3.6e-87 292.9 0.2 4.6e-87 292.5 0.1 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 EIE79258.1 - 7.5e-10 38.5 0.0 2e-09 37.1 0.0 1.7 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 EIE79258.1 - 0.0042 16.9 0.1 0.02 14.7 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain DUF1162 PF06650.7 EIE79259.1 - 8.1e-63 212.2 0.6 3.9e-60 203.4 0.0 3.0 2 1 1 3 3 3 2 Protein of unknown function (DUF1162) Chorein_N PF12624.2 EIE79259.1 - 1.2e-29 102.1 0.8 4.4e-29 100.4 0.6 2.0 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter Ribosomal_S3Ae PF01015.13 EIE79260.1 - 4.3e-66 221.9 5.6 5e-66 221.7 3.9 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Spt4 PF06093.8 EIE79260.1 - 0.081 12.8 0.3 0.73 9.7 0.0 2.3 2 0 0 2 2 2 0 Spt4/RpoE2 zinc finger DUF3571 PF12095.3 EIE79260.1 - 0.13 12.5 0.0 0.44 10.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3571) DUF496 PF04363.7 EIE79260.1 - 0.94 9.3 3.7 3.1 7.6 0.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF496) Ribosomal_S30 PF04758.9 EIE79261.1 - 3.9e-29 100.1 11.5 4.3e-29 100.0 8.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 IQ PF00612.22 EIE79262.1 - 3.8e-06 26.0 1.3 9.1e-06 24.8 0.9 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif SRP54 PF00448.17 EIE79262.1 - 0.052 12.9 2.1 0.21 11.0 1.3 2.0 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF2962 PF11176.3 EIE79262.1 - 4.8 6.7 25.7 0.85 9.1 7.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2962) NPV_P10 PF05531.7 EIE79262.1 - 8.2 6.7 10.8 0.63 10.3 0.6 2.8 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein MFS_1 PF07690.11 EIE79264.1 - 1.1e-32 113.1 70.7 1.6e-24 86.2 24.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DivIC PF04977.10 EIE79266.1 - 0.0027 17.1 1.8 0.0076 15.7 1.3 1.7 1 0 0 1 1 1 1 Septum formation initiator Lebercilin PF15619.1 EIE79266.1 - 0.013 14.9 2.5 0.013 14.9 1.7 1.6 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease TSC22 PF01166.13 EIE79266.1 - 0.015 15.2 0.1 0.033 14.1 0.1 1.6 1 0 0 1 1 1 0 TSC-22/dip/bun family Gag_spuma PF03276.9 EIE79266.1 - 0.29 9.4 7.3 0.38 9.0 5.1 1.1 1 0 0 1 1 1 0 Spumavirus gag protein Cep57_CLD_2 PF14197.1 EIE79266.1 - 1.1 9.3 4.0 1.1 9.2 1.6 1.9 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 MFS_1 PF07690.11 EIE79268.1 - 9.4e-28 96.9 51.7 1.7e-21 76.3 11.0 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily Ribosomal_S18 PF01084.15 EIE79270.1 - 1e-23 82.9 0.1 2.2e-23 81.8 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S18 GDI PF00996.13 EIE79271.1 - 2.6e-211 701.6 0.2 3e-211 701.3 0.1 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor DUF3661 PF12400.3 EIE79273.1 - 6.1e-17 61.9 6.0 7.7e-17 61.5 4.2 1.1 1 0 0 1 1 1 1 Vaculolar membrane protein SID-1_RNA_chan PF13965.1 EIE79273.1 - 0.11 10.6 0.1 0.13 10.3 0.0 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Gtr1_RagA PF04670.7 EIE79274.1 - 2.2e-97 324.7 0.3 2.6e-97 324.5 0.2 1.0 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 EIE79274.1 - 7.6e-07 28.5 0.0 1.1e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EIE79274.1 - 1.3e-06 27.9 0.0 1.9e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIE79274.1 - 0.00013 22.3 0.0 0.00031 21.2 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EIE79274.1 - 0.00026 20.9 0.0 0.00046 20.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EIE79274.1 - 0.00028 20.3 0.0 0.00033 20.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain DDE_3 PF13358.1 EIE79276.1 - 1e-17 64.2 0.0 2.1e-17 63.2 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 EIE79276.1 - 1.1e-05 25.4 0.0 7.8e-05 22.7 0.0 2.2 2 0 0 2 2 2 1 Winged helix-turn helix HTH_17 PF12728.2 EIE79276.1 - 0.00036 20.7 0.4 0.17 12.1 0.0 2.8 2 1 0 2 2 2 2 Helix-turn-helix domain HTH_23 PF13384.1 EIE79276.1 - 0.0025 17.3 0.3 0.033 13.8 0.0 2.6 3 0 0 3 3 3 1 Homeodomain-like domain HTH_32 PF13565.1 EIE79276.1 - 0.0028 18.4 0.0 0.014 16.1 0.0 2.1 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.1 EIE79276.1 - 0.0061 16.5 0.9 0.047 13.7 0.0 2.6 3 0 0 3 3 3 1 Helix-turn-helix domain Terminase_5 PF06056.7 EIE79276.1 - 0.012 15.1 0.2 0.012 15.1 0.1 2.4 3 0 0 3 3 3 0 Putative ATPase subunit of terminase (gpP-like) COX14 PF14880.1 EIE79277.1 - 0.049 13.2 1.4 0.072 12.7 0.9 1.3 1 1 0 1 1 1 0 Cytochrome oxidase c assembly ATP-synt_10 PF05176.9 EIE79277.1 - 0.06 12.6 0.1 0.063 12.5 0.1 1.0 1 0 0 1 1 1 0 ATP10 protein Mit_proteolip PF08039.6 EIE79277.1 - 0.13 12.2 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial proteolipid GFO_IDH_MocA PF01408.17 EIE79278.1 - 6.8e-28 97.5 0.0 1.2e-27 96.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EIE79278.1 - 2.8e-16 59.3 0.0 4.6e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Semialdhyde_dh PF01118.19 EIE79278.1 - 3.1e-05 24.2 0.0 5.8e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_3 PF03447.11 EIE79278.1 - 6.1e-05 23.4 0.0 0.0001 22.6 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain CoA_binding PF02629.14 EIE79278.1 - 0.0014 19.0 0.0 0.011 16.2 0.0 2.3 2 0 0 2 2 2 1 CoA binding domain WD40 PF00400.27 EIE79279.1 - 4.4e-26 89.7 4.6 4.2e-08 32.7 0.0 5.5 7 0 0 7 7 7 4 WD domain, G-beta repeat Dicty_CAD PF05720.7 EIE79279.1 - 0.024 14.2 0.0 0.082 12.5 0.0 1.9 1 0 0 1 1 1 0 Cell-cell adhesion domain eIF2A PF08662.6 EIE79279.1 - 0.025 14.2 0.0 0.095 12.3 0.0 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A MR_MLE_C PF13378.1 EIE79280.1 - 8.4e-17 61.1 0.0 2.2e-16 59.7 0.0 1.8 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 EIE79280.1 - 1.1e-15 57.8 0.4 3.2e-14 53.1 0.2 2.4 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 EIE79280.1 - 4.8e-06 26.5 0.0 1e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain GCR1_C PF12550.3 EIE79281.1 - 5.2e-26 90.3 0.7 5.1e-25 87.1 0.2 2.6 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes DDE_3 PF13358.1 EIE79282.1 - 2.9e-18 66.0 0.5 9.4e-18 64.3 0.0 2.1 3 0 0 3 3 3 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE79282.1 - 4.6e-11 42.6 0.7 1.1e-10 41.4 0.5 1.7 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.1 EIE79282.1 - 0.045 13.8 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn helix RVT_1 PF00078.22 EIE79283.1 - 7.7e-16 58.0 0.1 1.6e-15 57.0 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.12 EIE79283.1 - 5.3e-09 36.0 0.1 1.4e-08 34.7 0.1 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein UBN2 PF14223.1 EIE79283.1 - 0.094 12.5 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type DDE_3 PF13358.1 EIE79284.1 - 8.5e-13 48.2 1.9 1.1e-12 47.9 0.5 1.8 2 1 1 3 3 3 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE79284.1 - 1.4e-08 34.6 3.0 2.1e-08 34.1 0.3 2.4 1 1 1 2 2 2 1 Transposase rve PF00665.21 EIE79284.1 - 0.034 14.2 0.0 0.061 13.4 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain HTH_29 PF13551.1 EIE79284.1 - 0.051 13.7 1.3 0.15 12.1 0.9 1.9 1 1 0 1 1 1 0 Winged helix-turn helix HTH_12 PF08461.5 EIE79284.1 - 0.089 12.5 0.2 0.25 11.1 0.0 1.8 2 0 0 2 2 2 0 Ribonuclease R winged-helix domain ELL PF10390.4 EIE79284.1 - 0.12 11.5 0.8 0.28 10.3 0.5 1.6 1 0 0 1 1 1 0 RNA polymerase II elongation factor ELL HTH_32 PF13565.1 EIE79284.1 - 0.19 12.5 4.2 0.16 12.7 0.5 2.6 4 0 0 4 4 4 0 Homeodomain-like domain HTH_33 PF13592.1 EIE79284.1 - 0.23 11.0 1.3 0.74 9.4 0.0 2.5 3 0 0 3 3 3 0 Winged helix-turn helix HTH_21 PF13276.1 EIE79284.1 - 0.32 11.0 3.1 0.87 9.6 0.0 2.7 3 0 0 3 3 3 0 HTH-like domain NFRKB_winged PF14465.1 EIE79284.1 - 0.66 9.8 5.5 1.9 8.3 0.5 2.7 2 2 0 2 2 2 0 NFRKB Winged Helix-like HTH_Tnp_ISL3 PF13542.1 EIE79284.1 - 0.81 8.9 3.5 0.81 8.9 0.1 2.6 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 DUF1033 PF06279.6 EIE79284.1 - 1.7 8.5 6.3 0.49 10.2 0.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1033) rve PF00665.21 EIE79285.1 - 4e-23 81.8 0.0 9.7e-23 80.5 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.19 EIE79285.1 - 1.4e-08 34.3 0.1 2.6e-08 33.3 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 EIE79285.1 - 0.00041 19.6 1.6 0.00041 19.6 1.1 2.3 2 0 0 2 2 2 1 His(2)-Cys(2) zinc finger Tudor-knot PF11717.3 EIE79285.1 - 0.024 14.3 0.2 0.095 12.4 0.1 2.0 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain SYCE1 PF15233.1 EIE79286.1 - 0.0015 18.4 0.5 0.0023 17.8 0.3 1.2 1 0 0 1 1 1 1 Synaptonemal complex central element protein 1 TBPIP PF07106.8 EIE79286.1 - 0.049 13.1 0.1 0.075 12.5 0.0 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF972 PF06156.8 EIE79286.1 - 0.056 13.7 0.1 0.091 13.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF3450 PF11932.3 EIE79286.1 - 0.068 12.4 0.4 0.098 11.9 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) bZIP_1 PF00170.16 EIE79286.1 - 0.32 10.9 2.6 0.7 9.8 1.5 1.8 1 1 0 1 1 1 0 bZIP transcription factor Exo_endo_phos_2 PF14529.1 EIE79287.1 - 2e-15 56.4 0.1 4e-15 55.4 0.1 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RVT_1 PF00078.22 EIE79287.1 - 1.2e-06 28.0 0.0 1.9e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.18 EIE79287.1 - 9.7e-05 22.4 0.5 0.00018 21.5 0.0 1.7 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Lipase_3 PF01764.20 EIE79288.1 - 1.7e-17 63.3 0.0 3.2e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 EIE79288.1 - 0.0066 15.8 0.0 0.016 14.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.2 EIE79288.1 - 0.02 14.6 0.0 0.037 13.7 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.8 EIE79288.1 - 0.026 14.1 0.1 0.045 13.3 0.1 1.3 1 0 0 1 1 1 0 PGAP1-like protein GCD14_N PF14801.1 EIE79288.1 - 0.077 12.5 0.4 0.36 10.4 0.0 2.1 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit N-term PI3_PI4_kinase PF00454.22 EIE79290.1 - 2.6e-45 154.7 0.0 4.5e-45 153.9 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Nuc_sug_transp PF04142.10 EIE79291.1 - 4.4e-78 261.7 24.2 2.7e-45 154.4 2.2 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter EmrE PF13536.1 EIE79291.1 - 9.8e-08 32.1 1.1 9.8e-08 32.1 0.7 2.5 3 0 0 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 EIE79291.1 - 5.1e-07 29.7 3.1 5.1e-07 29.7 2.1 3.1 3 1 0 3 3 3 1 EamA-like transporter family TPT PF03151.11 EIE79291.1 - 0.00013 21.6 1.1 0.00013 21.6 0.8 2.8 2 1 0 2 2 2 1 Triose-phosphate Transporter family DUF4366 PF14283.1 EIE79291.1 - 0.00091 18.7 0.1 0.0015 18.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) UAA PF08449.6 EIE79291.1 - 0.067 12.1 22.4 4.7 6.0 15.6 2.8 1 1 0 1 1 1 0 UAA transporter family WD40 PF00400.27 EIE79293.1 - 1.6e-15 56.2 0.4 0.00033 20.4 0.0 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat Ribosomal_L7Ae PF01248.21 EIE79294.1 - 8.4e-28 95.7 1.9 1.1e-27 95.4 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF1193 PF06702.7 EIE79294.1 - 0.041 13.2 0.1 0.058 12.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1193) FliM PF02154.10 EIE79294.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.5 1 1 0 1 1 1 0 Flagellar motor switch protein FliM NAD_binding_3 PF03447.11 EIE79294.1 - 0.44 10.9 4.3 5.6 7.3 0.3 2.2 1 1 1 2 2 2 0 Homoserine dehydrogenase, NAD binding domain Ribosomal_S7e PF01251.13 EIE79295.1 - 8.4e-83 276.5 0.3 9.4e-83 276.3 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Vps54 PF07928.7 EIE79296.1 - 2.7e-39 134.4 0.7 2.7e-39 134.4 0.5 2.3 2 0 0 2 2 2 1 Vps54-like protein DUF2450 PF10475.4 EIE79296.1 - 1.7e-12 46.8 1.8 1.7e-12 46.8 1.3 2.0 2 0 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) DUF1446 PF07287.6 EIE79296.1 - 0.017 13.5 0.1 0.028 12.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1446) PH_9 PF15410.1 EIE79297.1 - 4.8e-07 29.9 0.7 2.8e-06 27.4 0.1 2.4 2 1 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 EIE79297.1 - 6.4e-06 26.3 0.7 1.1e-05 25.6 0.1 1.6 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 EIE79297.1 - 0.01 16.0 0.7 0.32 11.2 0.0 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain Med15_fungi PF05397.7 EIE79298.1 - 2.3e-18 66.2 4.4 2.3e-18 66.2 3.1 5.1 3 1 1 4 4 4 1 Mediator complex subunit 15 WD40 PF00400.27 EIE79300.1 - 7.7e-57 187.2 19.7 3.2e-10 39.4 0.1 7.5 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.2 EIE79300.1 - 4.8e-12 45.4 0.2 9.1e-12 44.5 0.1 1.5 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 EIE79300.1 - 3.1e-08 32.2 13.1 0.016 13.3 0.2 5.7 1 1 4 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EIE79300.1 - 0.00011 21.0 0.6 0.26 10.0 0.1 2.4 1 1 0 2 2 2 2 Nup133 N terminal like F-box PF00646.28 EIE79300.1 - 0.00054 19.5 0.0 0.001 18.6 0.0 1.5 1 0 0 1 1 1 1 F-box domain eIF2A PF08662.6 EIE79300.1 - 0.0018 18.0 0.0 0.068 12.8 0.0 2.7 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 EIE79300.1 - 0.011 14.0 0.2 0.13 10.4 0.0 2.5 2 2 0 2 2 2 0 Cytochrome D1 heme domain PQQ_3 PF13570.1 EIE79300.1 - 0.35 11.2 5.2 1.8 8.9 0.0 4.4 5 1 1 6 6 6 0 PQQ-like domain Glyco_transf_15 PF01793.11 EIE79301.1 - 3.8e-71 239.7 12.4 2.5e-42 144.9 1.1 2.0 1 1 1 2 2 2 2 Glycolipid 2-alpha-mannosyltransferase NTF2 PF02136.15 EIE79302.1 - 7.9e-29 100.4 0.3 2.3e-28 98.9 0.0 1.9 2 0 0 2 2 2 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.17 EIE79302.1 - 1.1e-12 47.4 0.1 2.2e-12 46.3 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE79302.1 - 4.4e-10 39.3 0.0 9.9e-10 38.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE79302.1 - 7.9e-06 25.6 0.0 1.7e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EIE79302.1 - 0.00089 19.0 0.0 0.00089 19.0 0.0 3.0 3 0 0 3 3 3 1 RNA binding motif DUF4350 PF14258.1 EIE79302.1 - 0.016 15.3 0.0 0.05 13.8 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4350) Nup35_RRM_2 PF14605.1 EIE79302.1 - 0.05 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Hexokinase_2 PF03727.11 EIE79303.1 - 2.5e-45 154.5 0.4 3.7e-45 154.0 0.3 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EIE79303.1 - 5.9e-41 140.0 0.0 8.7e-41 139.5 0.0 1.2 1 0 0 1 1 1 1 Hexokinase zf-C2H2 PF00096.21 EIE79304.1 - 1.5e-06 28.1 5.1 0.0025 18.0 0.3 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EIE79304.1 - 0.001 19.1 0.2 0.093 12.8 0.0 2.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 EIE79304.1 - 0.013 15.7 3.4 2 8.9 0.2 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.2 EIE79304.1 - 0.02 15.1 1.2 0.73 10.1 0.0 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type PIP5K PF01504.13 EIE79305.1 - 5.5e-36 123.9 1.4 5.5e-36 123.9 1.0 1.6 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase MCM2_N PF12619.3 EIE79305.1 - 0.019 14.9 2.6 0.029 14.3 1.8 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance protein 2 RPAP3_C PF13877.1 EIE79306.1 - 0.00016 21.5 1.2 0.00022 21.1 0.4 1.5 2 0 0 2 2 2 1 Potential Monad-binding region of RPAP3 Prp18 PF02840.10 EIE79306.1 - 0.072 12.9 0.2 0.072 12.9 0.1 1.1 1 0 0 1 1 1 0 Prp18 domain DHHW PF14286.1 EIE79307.1 - 0.34 10.1 6.6 0.45 9.7 4.5 1.1 1 0 0 1 1 1 0 DHHW protein YL1 PF05764.8 EIE79307.1 - 0.58 9.7 21.6 0.82 9.2 15.0 1.1 1 0 0 1 1 1 0 YL1 nuclear protein DUF2201_N PF13203.1 EIE79307.1 - 1.8 7.6 6.6 2.4 7.2 4.6 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Selenoprotein_S PF06936.6 EIE79307.1 - 2.1 7.8 10.1 3.2 7.2 7.0 1.3 1 0 0 1 1 1 0 Selenoprotein S (SelS) GOLD_2 PF13897.1 EIE79307.1 - 2.3 8.4 5.1 3.9 7.7 3.6 1.5 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking RR_TM4-6 PF06459.7 EIE79307.1 - 2.4 7.9 16.2 3.3 7.5 11.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF808 PF05661.7 EIE79307.1 - 3 6.6 3.9 3.9 6.2 2.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF808) Ycf1 PF05758.7 EIE79307.1 - 3.4 5.2 11.7 4.3 4.9 8.1 1.1 1 0 0 1 1 1 0 Ycf1 Toxin_43 PF15604.1 EIE79307.1 - 3.5 7.6 11.5 3.5 7.6 6.6 1.9 2 0 0 2 2 2 0 Putative toxin 43 V_ATPase_I PF01496.14 EIE79307.1 - 4.6 4.9 9.8 5.9 4.6 6.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Presenilin PF01080.12 EIE79307.1 - 6.1 5.5 5.7 7 5.3 3.9 1.1 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.9 EIE79307.1 - 7.1 4.5 10.1 9 4.1 7.0 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF740 PF05340.7 EIE79307.1 - 7.7 4.7 13.0 10 4.3 9.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF740) YyzF PF14116.1 EIE79308.1 - 0.025 14.5 2.5 0.09 12.7 0.5 2.1 2 0 0 2 2 2 0 YyzF-like protein DUF4492 PF14899.1 EIE79309.1 - 0.099 12.1 1.3 0.18 11.3 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4492) Trehalase PF01204.13 EIE79310.1 - 6.6e-179 595.8 1.6 7.8e-179 595.5 1.1 1.0 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 EIE79310.1 - 4e-14 51.6 1.0 8.5e-14 50.5 0.7 1.5 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain YvbH_ext PF11724.3 EIE79310.1 - 0.048 13.3 0.0 2.5 7.8 0.0 3.1 3 0 0 3 3 3 0 YvbH-like oligomerisation region DAO PF01266.19 EIE79311.1 - 1e-29 103.5 0.0 1.2e-29 103.3 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EIE79311.1 - 0.00014 20.8 0.0 0.0002 20.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EIE79311.1 - 0.00044 20.2 0.3 0.0041 17.0 0.2 2.7 4 0 0 4 4 4 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EIE79311.1 - 0.0084 16.0 0.3 0.032 14.1 0.2 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EIE79311.1 - 0.0095 15.0 0.3 0.02 13.9 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EIE79311.1 - 0.0095 15.0 0.1 0.026 13.6 0.0 1.7 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.1 EIE79311.1 - 0.04 13.9 0.0 0.083 12.9 0.0 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EIE79311.1 - 0.055 13.5 0.4 6.5 6.8 0.3 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.1 EIE79311.1 - 0.072 12.8 0.5 2.4 7.8 0.1 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_oxidored PF12831.2 EIE79311.1 - 0.11 11.4 0.1 0.64 9.0 0.1 2.0 1 1 0 1 1 1 0 FAD dependent oxidoreductase DivIC PF04977.10 EIE79312.1 - 0.0049 16.3 1.7 0.013 15.0 1.2 1.6 1 0 0 1 1 1 1 Septum formation initiator Lebercilin PF15619.1 EIE79312.1 - 0.02 14.3 2.4 0.02 14.3 1.6 1.5 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Herpes_BLRF2 PF05812.7 EIE79312.1 - 0.03 14.1 0.1 0.058 13.2 0.1 1.4 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein SlyX PF04102.7 EIE79312.1 - 0.17 12.2 2.2 0.41 11.0 1.5 1.6 1 0 0 1 1 1 0 SlyX Shugoshin_N PF07558.6 EIE79312.1 - 0.52 10.0 3.1 0.61 9.8 0.2 2.7 2 1 0 2 2 2 0 Shugoshin N-terminal coiled-coil region DUF605 PF04652.11 EIE79312.1 - 0.58 9.4 8.7 0.76 9.1 6.1 1.1 1 0 0 1 1 1 0 Vta1 like Cep57_CLD_2 PF14197.1 EIE79312.1 - 1.8 8.5 4.4 3.7 7.5 1.6 2.2 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Transposase_31 PF04754.7 EIE79313.1 - 3.7e-05 23.1 0.1 7.5e-05 22.1 0.1 1.5 1 1 0 2 2 2 1 Putative transposase, YhgA-like PDDEXK_2 PF12784.2 EIE79313.1 - 0.00059 19.0 2.0 0.00094 18.4 1.4 1.3 1 1 0 1 1 1 1 PD-(D/E)XK nuclease family transposase DUF2887 PF11103.3 EIE79313.1 - 0.042 13.4 0.1 0.055 13.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2887) DEAD PF00270.24 EIE79315.1 - 1.7e-37 128.4 0.3 5.5e-37 126.8 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIE79315.1 - 3.7e-27 93.9 0.0 2.5e-26 91.3 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIE79315.1 - 0.00011 22.1 0.3 0.00076 19.3 0.0 2.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 EIE79315.1 - 0.0024 16.9 0.0 0.0051 15.9 0.0 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit FUN14 PF04930.10 EIE79316.1 - 1.6e-26 92.5 0.4 1.9e-26 92.2 0.3 1.1 1 0 0 1 1 1 1 FUN14 family rve PF00665.21 EIE79318.1 - 2.6e-12 46.8 0.0 6.2e-12 45.6 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.1 EIE79318.1 - 0.026 14.0 0.0 0.061 12.8 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain RVT_1 PF00078.22 EIE79319.1 - 9.4e-21 74.1 0.0 1.6e-20 73.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 EIE79320.1 - 4.6e-08 33.4 0.0 1.1e-07 32.1 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.12 EIE79320.1 - 6e-08 32.6 0.3 1.2e-07 31.6 0.2 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.18 EIE79320.1 - 0.00077 19.2 1.3 0.0014 18.4 0.9 1.5 1 0 0 1 1 1 1 Zinc knuckle gag-asp_proteas PF13975.1 EIE79320.1 - 0.0089 15.8 0.0 0.027 14.2 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 EIE79320.1 - 0.0094 15.8 0.0 0.024 14.5 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.6 EIE79320.1 - 0.021 14.7 0.0 0.041 13.8 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease GCR1_C PF12550.3 EIE79322.1 - 5e-26 90.3 0.7 5.1e-25 87.1 0.2 2.7 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes Cir_N PF10197.4 EIE79323.1 - 5.5 7.1 7.3 1 9.4 0.6 2.1 2 0 0 2 2 2 0 N-terminal domain of CBF1 interacting co-repressor CIR zf-Sec23_Sec24 PF04810.10 EIE79324.1 - 0.053 13.0 1.5 0.15 11.6 0.1 2.4 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Sgf11 PF08209.6 EIE79324.1 - 0.36 10.1 3.3 1.8 7.9 0.1 2.3 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Docking PF08990.6 EIE79324.1 - 0.57 9.4 3.6 2.9 7.1 0.7 2.5 2 0 0 2 2 2 0 Erythronolide synthase docking Ima1_N PF09779.4 EIE79324.1 - 2.6 8.5 8.4 0.54 10.7 1.2 3.0 2 1 1 3 3 3 0 Ima1 N-terminal domain TMF_TATA_bd PF12325.3 EIE79324.1 - 2.7 7.7 8.3 0.35 10.5 1.6 2.7 3 1 0 3 3 3 0 TATA element modulatory factor 1 TATA binding RVT_1 PF00078.22 EIE79325.1 - 9.2e-18 64.3 0.0 1.8e-17 63.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) NAD_Gly3P_dh_N PF01210.18 EIE79327.1 - 7.2e-53 178.5 0.3 2.5e-52 176.7 0.1 1.8 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 EIE79327.1 - 6e-45 152.6 2.5 6e-45 152.6 1.7 1.9 2 1 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.12 EIE79327.1 - 3.9e-06 27.1 0.5 5.5e-05 23.5 0.4 2.5 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.19 EIE79327.1 - 0.0028 17.9 0.1 0.011 16.0 0.1 1.9 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain PAS PF00989.19 EIE79327.1 - 0.019 14.7 0.0 0.035 13.8 0.0 1.4 1 0 0 1 1 1 0 PAS fold IlvN PF07991.7 EIE79327.1 - 0.033 13.5 0.0 0.76 9.1 0.0 2.4 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain CoA_binding PF02629.14 EIE79327.1 - 0.035 14.6 0.7 0.58 10.7 0.5 2.6 1 1 0 1 1 1 0 CoA binding domain 3HCDH_N PF02737.13 EIE79327.1 - 0.043 13.4 0.0 0.078 12.6 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 EIE79327.1 - 0.069 12.5 0.1 0.18 11.2 0.1 1.7 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TPR_12 PF13424.1 EIE79328.1 - 6.9e-14 51.5 9.2 6.3e-09 35.6 0.1 4.2 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EIE79328.1 - 1.4e-09 37.4 8.8 3.6e-06 26.5 0.6 3.0 4 0 0 4 4 4 2 TPR repeat TPR_1 PF00515.23 EIE79328.1 - 2.4e-06 26.9 16.1 0.088 12.4 0.1 5.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 EIE79328.1 - 0.00045 19.9 17.9 0.0084 15.9 0.1 5.1 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_10 PF13374.1 EIE79328.1 - 0.0016 18.3 0.1 0.0016 18.3 0.0 3.7 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 EIE79328.1 - 0.0038 17.3 0.9 0.11 12.7 0.1 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 EIE79328.1 - 0.0069 16.4 0.7 0.44 10.7 0.0 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 EIE79328.1 - 0.0093 15.6 12.4 0.57 10.0 0.1 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat DUF2225 PF09986.4 EIE79328.1 - 0.012 15.0 0.1 1.4 8.3 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_7 PF13176.1 EIE79328.1 - 0.098 12.5 3.5 5.5 7.0 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.1 EIE79328.1 - 0.25 11.6 7.3 0.61 10.4 0.0 3.0 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 EIE79328.1 - 0.38 11.4 9.5 3 8.6 0.9 3.8 3 2 0 3 3 3 0 Tetratricopeptide repeat ADIP PF11559.3 EIE79329.1 - 6.8e-05 22.8 16.1 6.8e-05 22.8 11.2 3.5 2 1 0 3 3 3 1 Afadin- and alpha -actinin-Binding RBD-FIP PF09457.5 EIE79329.1 - 0.006 16.3 3.8 0.006 16.3 2.6 3.1 4 0 0 4 4 4 1 FIP domain TMF_TATA_bd PF12325.3 EIE79329.1 - 0.0097 15.6 7.5 0.0097 15.6 5.2 3.7 3 1 0 3 3 3 1 TATA element modulatory factor 1 TATA binding MbeB_N PF04837.7 EIE79329.1 - 0.056 13.5 0.3 0.056 13.5 0.2 3.4 3 0 0 3 3 3 0 MbeB-like, N-term conserved region Formyl_trans_C PF02911.13 EIE79329.1 - 0.074 13.1 0.1 1.3 9.1 0.0 2.4 2 0 0 2 2 2 0 Formyl transferase, C-terminal domain ATG16 PF08614.6 EIE79329.1 - 0.42 10.4 32.8 0.99 9.1 6.9 3.5 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) DUF4140 PF13600.1 EIE79329.1 - 1.2 9.6 13.4 3.4 8.1 0.1 3.6 3 1 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) TMF_DNA_bd PF12329.3 EIE79329.1 - 1.7 8.5 41.6 0.063 13.0 2.2 4.4 3 1 2 5 5 5 0 TATA element modulatory factor 1 DNA binding SlyX PF04102.7 EIE79329.1 - 1.9 8.8 33.9 0.26 11.6 2.4 3.9 4 0 0 4 4 4 0 SlyX GCR1_C PF12550.3 EIE79330.1 - 5.1e-26 90.3 0.7 5.1e-25 87.1 0.2 2.6 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes HLH PF00010.21 EIE79332.1 - 8.9e-14 50.9 0.5 6.1e-13 48.2 0.1 2.3 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF2334 PF10096.4 EIE79332.1 - 0.047 13.1 1.6 5.2 6.4 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2334) DUF2366 PF10171.4 EIE79332.1 - 0.12 11.8 0.3 0.18 11.3 0.2 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2366) RP-C_C PF11800.3 EIE79332.1 - 1.1 8.9 15.2 1.7 8.3 6.9 2.2 1 1 1 2 2 2 0 Replication protein C C-terminal region Draxin PF15550.1 EIE79332.1 - 1.9 8.0 12.0 2.6 7.6 8.3 1.1 1 0 0 1 1 1 0 Draxin CENP-H PF05837.7 EIE79332.1 - 8.2 6.6 14.0 6 7.1 8.2 1.9 1 1 0 1 1 1 0 Centromere protein H (CENP-H) Gpi16 PF04113.9 EIE79333.1 - 2.5e-87 293.2 0.6 3.1e-87 292.9 0.4 1.2 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component Methyltransf_31 PF13847.1 EIE79334.1 - 4.2e-13 49.1 0.1 4.6e-12 45.7 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIE79334.1 - 3e-12 46.8 0.0 6.9e-12 45.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIE79334.1 - 1.7e-09 37.6 0.0 2.9e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIE79334.1 - 2.4e-09 37.4 0.0 5.2e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIE79334.1 - 1.1e-07 31.2 0.0 8.7e-07 28.2 0.0 2.3 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EIE79334.1 - 3.5e-07 30.8 0.0 8.1e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EIE79334.1 - 2.4e-06 26.7 0.0 2.1e-05 23.6 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_12 PF08242.7 EIE79334.1 - 4.2e-06 27.1 0.0 2e-05 24.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EIE79334.1 - 9.2e-06 25.4 0.0 1.5e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase CMAS PF02353.15 EIE79334.1 - 2.5e-05 23.5 0.0 0.00013 21.1 0.0 1.9 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.13 EIE79334.1 - 0.0029 16.8 0.0 0.0039 16.4 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase MTS PF05175.9 EIE79334.1 - 0.0042 16.4 0.0 0.0082 15.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain DOT1 PF08123.8 EIE79334.1 - 0.0055 16.0 0.0 0.016 14.4 0.0 1.8 1 0 0 1 1 1 1 Histone methylation protein DOT1 FtsJ PF01728.14 EIE79334.1 - 0.011 15.6 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_9 PF08003.6 EIE79334.1 - 0.011 14.3 0.0 0.018 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) MetW PF07021.7 EIE79334.1 - 0.07 12.5 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_26 PF13659.1 EIE79334.1 - 0.095 12.7 0.0 0.23 11.4 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 EIE79334.1 - 0.11 11.4 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PCMT PF01135.14 EIE79334.1 - 0.17 11.3 0.0 0.27 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CTP_transf_2 PF01467.21 EIE79335.1 - 1.4e-21 77.1 0.0 1.9e-21 76.7 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase RIO1 PF01163.17 EIE79337.1 - 6.1e-46 156.1 0.0 6.1e-46 156.1 0.0 2.3 3 0 0 3 3 3 1 RIO1 family Rio2_N PF09202.6 EIE79337.1 - 5.1e-35 119.3 1.4 2.3e-34 117.3 0.1 2.5 2 0 0 2 2 2 1 Rio2, N-terminal APH PF01636.18 EIE79337.1 - 2.2e-09 37.4 0.0 0.00017 21.3 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EIE79337.1 - 1.5e-06 27.4 0.0 0.024 13.7 0.0 2.5 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EIE79337.1 - 0.034 13.0 0.0 0.068 12.1 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Peptidase_S8 PF00082.17 EIE79338.1 - 4e-32 111.5 0.2 4.6e-32 111.2 0.1 1.0 1 0 0 1 1 1 1 Subtilase family Abhydrolase_6 PF12697.2 EIE79339.1 - 4.9e-33 114.9 0.0 6.6e-33 114.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIE79339.1 - 4.7e-18 65.3 0.0 1e-17 64.2 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIE79339.1 - 2.1e-16 60.1 0.1 1.5e-08 34.4 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EIE79339.1 - 2e-08 33.9 0.3 5.3e-08 32.6 0.2 1.7 1 0 0 1 1 1 1 Putative lysophospholipase DLH PF01738.13 EIE79339.1 - 9.2e-05 21.8 0.0 0.016 14.5 0.0 3.2 2 1 0 2 2 2 1 Dienelactone hydrolase family Ndr PF03096.9 EIE79339.1 - 0.0001 20.9 0.4 0.00018 20.1 0.0 1.7 2 0 0 2 2 2 1 Ndr family Abhydrolase_4 PF08386.5 EIE79339.1 - 0.0001 22.1 0.0 0.00035 20.4 0.0 1.8 2 0 0 2 2 2 1 TAP-like protein BAAT_C PF08840.6 EIE79339.1 - 0.014 15.0 0.0 0.05 13.2 0.0 1.9 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Thioesterase PF00975.15 EIE79339.1 - 0.036 14.2 0.0 0.085 13.0 0.0 1.6 1 0 0 1 1 1 0 Thioesterase domain Syntaxin PF00804.20 EIE79339.1 - 1.5 8.9 11.3 0.46 10.6 5.2 2.0 2 1 0 2 2 2 0 Syntaxin Rep_fac-A_C PF08646.5 EIE79340.1 - 0.36 10.5 7.2 0.1 12.3 2.5 1.8 2 0 0 2 2 2 0 Replication factor-A C terminal domain Tetraspannin PF00335.15 EIE79341.1 - 1.8e-15 56.7 6.8 2.5e-15 56.3 4.7 1.1 1 0 0 1 1 1 1 Tetraspanin family Fanconi_A PF03511.9 EIE79341.1 - 0.12 12.1 0.3 0.32 10.8 0.2 1.6 1 0 0 1 1 1 0 Fanconi anaemia group A protein DUF4064 PF13273.1 EIE79341.1 - 0.26 11.3 7.5 0.91 9.6 4.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) FAM70 PF14967.1 EIE79341.1 - 0.33 10.1 6.9 0.78 8.8 4.8 1.6 1 1 0 1 1 1 0 FAM70 protein ETF PF01012.16 EIE79342.1 - 8.1e-42 142.7 0.4 1e-41 142.3 0.3 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain GCR1_C PF12550.3 EIE79343.1 - 2.5e-13 49.6 0.3 8.4e-13 48.0 0.2 1.9 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes DnaJ_CXXCXGXG PF00684.14 EIE79344.1 - 0.036 14.1 7.5 1.1 9.3 1.7 2.6 2 0 0 2 2 2 0 DnaJ central domain zf-CCHC PF00098.18 EIE79344.1 - 0.056 13.4 18.9 0.061 13.2 1.3 2.8 3 0 0 3 3 3 0 Zinc knuckle RVT_1 PF00078.22 EIE79345.1 - 2.1e-32 112.2 0.0 4.4e-32 111.1 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.1 EIE79345.1 - 0.0028 17.9 2.3 0.012 15.8 1.6 2.2 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Claudin_3 PF06653.6 EIE79347.1 - 0.14 11.8 2.0 0.16 11.6 1.4 1.0 1 0 0 1 1 1 0 Tight junction protein, Claudin-like ANF_receptor PF01094.23 EIE79349.1 - 7.8e-29 100.5 2.1 1e-28 100.1 1.4 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.1 EIE79349.1 - 3.8e-18 65.9 1.2 5.1e-18 65.5 0.8 1.2 1 1 0 1 1 1 1 Periplasmic binding protein Aminotran_1_2 PF00155.16 EIE79350.1 - 1.4e-39 136.1 0.0 1.1e-38 133.1 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EIE79350.1 - 0.012 14.8 0.0 0.021 13.9 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase STAG PF08514.6 EIE79351.1 - 1.3e-25 89.3 0.4 1.3e-25 89.3 0.3 4.2 5 1 1 6 6 6 1 STAG domain PqqD PF05402.7 EIE79351.1 - 0.02 14.8 0.8 1.9 8.5 0.0 3.2 2 0 0 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) PAS_11 PF14598.1 EIE79351.1 - 0.026 14.4 3.1 0.16 11.9 0.1 3.4 3 0 0 3 3 3 0 PAS domain DHO_dh PF01180.16 EIE79352.1 - 7.4e-66 222.1 0.0 8.4e-66 221.9 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase PcrB PF01884.12 EIE79352.1 - 0.083 12.1 0.4 0.19 10.9 0.1 1.7 3 0 0 3 3 3 0 PcrB family DUF885 PF05960.6 EIE79352.1 - 0.097 11.8 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) HSP70 PF00012.15 EIE79353.1 - 5.4e-91 305.3 12.4 5.4e-91 305.3 8.6 2.5 2 1 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 EIE79353.1 - 5.8e-08 31.7 2.5 5.1e-07 28.5 1.7 2.1 1 1 0 1 1 1 1 MreB/Mbl protein UPF0102 PF02021.12 EIE79354.1 - 0.12 12.2 0.1 0.14 12.0 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0102 DDE_3 PF13358.1 EIE79355.1 - 1.4e-13 50.7 0.0 1.9e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease PH PF00169.24 EIE79356.1 - 1.2e-06 28.6 3.3 1.2e-06 28.6 2.3 2.0 2 0 0 2 2 2 1 PH domain DUF2387 PF09526.5 EIE79356.1 - 0.085 12.7 0.1 0.3 11.0 0.0 2.0 3 0 0 3 3 3 0 Probable metal-binding protein (DUF2387) PCNA_N PF00705.13 EIE79356.1 - 0.1 12.1 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Proliferating cell nuclear antigen, N-terminal domain Mcp5_PH PF12814.2 EIE79356.1 - 0.13 12.2 6.7 0.15 11.9 2.0 2.7 2 1 0 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology PH_11 PF15413.1 EIE79356.1 - 5.2 7.3 9.2 48 4.2 2.9 3.1 2 1 0 2 2 2 0 Pleckstrin homology domain UPF0020 PF01170.13 EIE79357.1 - 6.4e-14 51.9 0.0 1.2e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 EIE79357.1 - 3.3e-10 40.0 0.0 5.9e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.11 EIE79357.1 - 0.00028 20.0 0.0 0.00052 19.1 0.0 1.4 1 0 0 1 1 1 1 N-6 DNA Methylase N6_N4_Mtase PF01555.13 EIE79357.1 - 0.00051 19.5 0.0 0.25 10.8 0.0 2.7 2 2 0 2 2 2 2 DNA methylase Y_phosphatase3 PF13350.1 EIE79358.1 - 1.3e-41 142.5 0.0 1.6e-41 142.3 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 EIE79358.1 - 8.2e-05 22.0 0.0 0.00012 21.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 EIE79358.1 - 0.025 14.1 0.0 0.039 13.5 0.0 1.3 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 EIE79358.1 - 0.12 12.4 0.1 0.2 11.7 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate LRR_6 PF13516.1 EIE79359.1 - 1.3e-05 24.8 0.3 1.2 9.4 0.0 5.5 7 0 0 7 7 7 1 Leucine Rich repeat LRR_1 PF00560.28 EIE79359.1 - 0.001 18.8 0.2 36 4.9 0.0 4.8 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_7 PF13504.1 EIE79359.1 - 0.0095 15.9 3.1 8 7.1 0.0 5.3 5 1 0 5 5 5 1 Leucine rich repeat DUF2414 PF10309.4 EIE79359.1 - 0.072 12.7 0.1 7.8 6.2 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2414) C2 PF00168.25 EIE79361.1 - 1.7e-17 63.0 0.0 2.7e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 C2 domain DUF2605 PF10792.4 EIE79361.1 - 0.12 12.1 0.4 1.1 9.0 0.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF2605) DUF791 PF05631.9 EIE79365.1 - 0.16 10.6 0.0 0.23 10.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF791) Myc_N PF01056.13 EIE79365.1 - 0.9 8.6 3.3 1.2 8.1 2.3 1.1 1 0 0 1 1 1 0 Myc amino-terminal region CTP_transf_2 PF01467.21 EIE79366.1 - 1.8e-23 83.3 0.4 4e-23 82.1 0.0 1.8 2 0 0 2 2 2 1 Cytidylyltransferase TPD PF14811.1 EIE79366.1 - 0.032 13.7 0.5 0.069 12.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function TPD sequence-motif DUF2458 PF10454.4 EIE79367.1 - 5.4e-09 36.1 17.7 5.4e-09 36.1 12.3 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF2458) DGCR6 PF07324.6 EIE79367.1 - 7.1e-09 35.4 16.4 1e-07 31.6 11.4 2.0 1 1 0 1 1 1 1 DiGeorge syndrome critical region 6 (DGCR6) protein RNase_E_G PF10150.4 EIE79368.1 - 0.012 14.8 2.5 0.015 14.5 1.8 1.3 1 0 0 1 1 1 0 Ribonuclease E/G family CtIP_N PF10482.4 EIE79368.1 - 0.02 14.6 7.1 0.032 14.0 4.9 1.4 1 0 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain DUF2216 PF10226.4 EIE79368.1 - 0.022 14.3 5.5 1.1 8.7 0.4 2.1 2 0 0 2 2 2 0 Uncharacterized conserved proteins (DUF2216) HAP1_N PF04849.8 EIE79368.1 - 0.055 12.4 10.2 0.072 12.0 7.1 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region Herpes_UL33 PF03581.8 EIE79368.1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Herpesvirus UL33-like protein Relaxase PF03432.9 EIE79368.1 - 1.3 8.3 6.7 1.9 7.7 4.7 1.3 1 1 0 1 1 1 0 Relaxase/Mobilisation nuclease domain LUC7 PF03194.10 EIE79368.1 - 1.3 8.4 7.2 1.6 8.2 5.0 1.1 1 0 0 1 1 1 0 LUC7 N_terminus DUF972 PF06156.8 EIE79368.1 - 3.2 8.1 12.9 2.8 8.3 3.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) NYD-SP28_assoc PF14775.1 EIE79368.1 - 5 6.8 10.9 1.1 9.0 2.2 2.8 2 1 0 2 2 2 0 Sperm tail C-terminal domain TSC22 PF01166.13 EIE79368.1 - 6.1 6.8 8.6 0.74 9.8 0.9 2.5 2 1 0 2 2 2 0 TSC-22/dip/bun family Thymidylat_synt PF00303.14 EIE79369.1 - 1.1e-119 398.4 0.0 1.2e-119 398.2 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase EF1_GNE PF00736.14 EIE79370.1 - 2.8e-32 110.2 1.1 5.4e-32 109.3 0.8 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 EIE79370.1 - 5.4e-13 48.8 5.4 5.4e-13 48.8 3.7 2.3 3 0 0 3 3 3 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.1 EIE79370.1 - 0.00059 20.2 0.0 0.0013 19.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF2777 PF10949.3 EIE79370.1 - 0.077 12.6 1.8 0.32 10.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2777) YvrJ PF12841.2 EIE79370.1 - 0.27 10.5 0.9 17 4.7 0.1 2.3 2 0 0 2 2 2 0 YvrJ protein family KCl_Cotrans_1 PF03522.10 EIE79370.1 - 1.5 8.4 4.2 0.61 9.6 0.2 2.3 2 0 0 2 2 2 0 K-Cl Co-transporter type 1 (KCC1) Sec23_trunk PF04811.10 EIE79371.1 - 3e-74 249.4 0.0 5.3e-74 248.6 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EIE79371.1 - 1.3e-23 82.3 0.0 3e-23 81.2 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 EIE79371.1 - 7.7e-18 63.7 2.7 1.8e-17 62.6 1.9 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 EIE79371.1 - 1.5e-16 60.6 0.0 3.6e-16 59.4 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain VWA PF00092.23 EIE79371.1 - 0.014 15.1 0.1 0.032 13.9 0.1 1.6 1 0 0 1 1 1 0 von Willebrand factor type A domain Gelsolin PF00626.17 EIE79371.1 - 0.018 14.6 0.0 0.056 13.1 0.0 1.8 1 0 0 1 1 1 0 Gelsolin repeat VWA_2 PF13519.1 EIE79371.1 - 0.031 14.3 0.0 0.06 13.4 0.0 1.5 1 0 0 1 1 1 0 von Willebrand factor type A domain Sen15 PF09631.5 EIE79371.1 - 0.047 13.9 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 Sen15 protein PEX11 PF05648.9 EIE79372.1 - 2.1e-31 108.9 0.0 2.5e-31 108.6 0.0 1.1 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) PPR_2 PF13041.1 EIE79373.1 - 1.4e-28 98.6 2.6 1.1e-10 41.2 0.3 4.8 3 2 2 5 5 5 5 PPR repeat family PPR_3 PF13812.1 EIE79373.1 - 1.1e-16 59.5 0.3 0.0018 18.4 0.0 6.3 6 0 0 6 6 6 3 Pentatricopeptide repeat domain PPR PF01535.15 EIE79373.1 - 1.8e-13 49.4 1.6 0.023 14.6 0.0 6.6 6 1 0 6 6 6 3 PPR repeat PPR_1 PF12854.2 EIE79373.1 - 3.4e-09 36.0 2.7 0.0029 17.0 0.0 6.4 7 1 0 7 7 7 2 PPR repeat RPM2 PF08579.6 EIE79373.1 - 0.00017 21.7 0.2 2.7 8.1 0.0 3.2 2 1 1 3 3 3 2 Mitochondrial ribonuclease P subunit (RPM2) CAP PF00188.21 EIE79373.1 - 0.067 13.6 0.0 0.1 13.0 0.0 1.2 1 0 0 1 1 1 0 Cysteine-rich secretory protein family ECSIT PF06239.6 EIE79373.1 - 0.11 11.3 0.1 9.6 4.9 0.0 2.6 2 1 1 3 3 3 0 Evolutionarily conserved signalling intermediate in Toll pathway FA_desaturase PF00487.19 EIE79374.1 - 3.8e-27 95.3 19.1 6.2e-27 94.6 13.2 1.3 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 EIE79374.1 - 2.1e-08 34.2 0.0 4.8e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Mito_carr PF00153.22 EIE79377.1 - 8e-57 188.9 9.7 9.4e-20 70.1 0.1 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein CAP PF00188.21 EIE79379.1 - 4.8e-26 91.6 5.4 6.2e-26 91.3 3.7 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family zf-PARP PF00645.13 EIE79380.1 - 4.7e-11 42.7 1.0 4.7e-11 42.7 0.7 2.5 2 1 0 2 2 2 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region RR_TM4-6 PF06459.7 EIE79380.1 - 2 8.2 14.1 2.9 7.7 9.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNase_H2-Ydr279 PF09468.5 EIE79380.1 - 2.5 7.2 18.8 4.8 6.2 13.0 1.4 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) P5CR_dimer PF14748.1 EIE79381.1 - 7.5e-38 128.8 0.4 1.2e-37 128.1 0.3 1.3 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 EIE79381.1 - 3.7e-10 40.0 0.0 1.2e-09 38.4 0.0 1.9 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 EIE79381.1 - 3.3e-07 30.1 0.6 2.1e-06 27.5 0.1 2.3 1 1 2 3 3 3 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus CRM1_C PF08767.6 EIE79381.1 - 0.068 12.0 0.0 0.098 11.5 0.0 1.2 1 0 0 1 1 1 0 CRM1 C terminal PDH PF02153.12 EIE79381.1 - 0.086 11.7 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Prephenate dehydrogenase Pkinase PF00069.20 EIE79382.1 - 7.9e-46 156.3 0.0 1.3e-44 152.3 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Mito_carr PF00153.22 EIE79382.1 - 6e-40 134.8 0.5 2.7e-17 62.2 0.0 3.4 2 1 1 3 3 3 3 Mitochondrial carrier protein Pkinase_Tyr PF07714.12 EIE79382.1 - 8.6e-30 103.6 0.0 5.6e-29 100.9 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE79382.1 - 7e-07 28.4 0.0 1.2e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EIE79382.1 - 0.015 15.0 0.3 0.028 14.1 0.2 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Cytochrom_C PF00034.16 EIE79384.1 - 3.5e-11 43.7 0.3 7.3e-11 42.7 0.2 1.5 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 EIE79384.1 - 2.3e-09 37.2 3.4 3.1e-08 33.6 2.3 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 EIE79384.1 - 0.00055 19.3 0.6 0.01 15.2 0.1 2.2 2 0 0 2 2 2 1 Cytochrome c-550 domain CCP_MauG PF03150.9 EIE79384.1 - 0.034 14.4 0.0 0.04 14.2 0.0 1.2 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase ER_lumen_recept PF00810.13 EIE79387.1 - 0.00046 20.6 7.5 0.00058 20.3 3.0 2.0 2 0 0 2 2 2 1 ER lumen protein retaining receptor AMP-binding PF00501.23 EIE79388.1 - 1.3e-69 234.6 0.1 1.8e-69 234.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Ham1p_like PF01725.11 EIE79388.1 - 2.3e-52 177.1 0.0 3.2e-52 176.6 0.0 1.2 1 0 0 1 1 1 1 Ham1 family AMP-binding_C PF13193.1 EIE79388.1 - 1.9e-19 70.3 0.0 5.2e-19 68.9 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain WD40 PF00400.27 EIE79389.1 - 5.5e-67 219.4 11.3 1.7e-10 40.3 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 EIE79389.1 - 7.2e-24 83.7 17.0 1.1e-23 83.2 11.8 1.3 1 0 0 1 1 1 1 Tup N-terminal Cytochrom_D1 PF02239.11 EIE79389.1 - 0.00052 18.4 0.5 0.004 15.4 0.2 2.3 1 1 1 2 2 2 1 Cytochrome D1 heme domain Nup160 PF11715.3 EIE79389.1 - 0.0011 17.1 2.2 0.024 12.8 0.3 3.5 1 1 2 3 3 3 1 Nucleoporin Nup120/160 Nbas_N PF15492.1 EIE79389.1 - 0.0029 16.7 0.1 1 8.4 0.0 2.9 1 1 1 3 3 3 1 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.6 EIE79389.1 - 0.012 14.3 0.5 14 4.2 0.0 3.8 1 1 3 4 4 4 0 Nup133 N terminal like PD40 PF07676.7 EIE79389.1 - 0.013 15.1 0.2 2.4 7.9 0.0 3.4 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat DUF3450 PF11932.3 EIE79389.1 - 0.068 12.4 12.0 0.12 11.6 8.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DivIVA PF05103.8 EIE79389.1 - 0.18 11.8 6.6 0.33 11.0 4.6 1.3 1 0 0 1 1 1 0 DivIVA protein USP8_interact PF08941.5 EIE79389.1 - 0.84 8.9 4.6 1.6 8.0 3.2 1.4 1 0 0 1 1 1 0 USP8 interacting THOC7 PF05615.8 EIE79389.1 - 1.6 9.0 9.5 2.5 8.3 6.6 1.2 1 0 0 1 1 1 0 Tho complex subunit 7 Phage_Mu_Gam PF07352.7 EIE79389.1 - 2.2 7.7 7.1 2.1 7.8 3.4 1.9 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein APG6 PF04111.7 EIE79389.1 - 4.5 6.2 10.9 6.4 5.7 7.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 UCH PF00443.24 EIE79390.1 - 5.8e-49 166.6 1.2 5.8e-49 166.6 0.8 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EIE79390.1 - 2.4e-20 73.1 10.3 1.4e-16 60.7 1.4 3.2 2 1 1 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EIE79390.1 - 2.9e-17 62.5 8.3 1.7e-13 50.4 1.5 3.9 5 0 0 5 5 5 2 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.26 EIE79390.1 - 1.9e-13 49.8 6.3 7.4e-09 35.1 0.3 2.8 3 0 0 3 3 3 2 UBA/TS-N domain DUF4176 PF13780.1 EIE79390.1 - 0.13 12.0 0.0 0.33 10.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4176) UQ_con PF00179.21 EIE79391.1 - 5e-35 119.9 0.0 8.9e-35 119.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EIE79391.1 - 0.015 15.0 0.0 0.026 14.2 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic E2 family B ResIII PF04851.10 EIE79391.1 - 0.032 14.0 0.6 0.041 13.7 0.4 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit PP2C PF00481.16 EIE79392.1 - 1.4e-21 77.0 0.0 5.4e-20 71.8 0.0 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C Spo0A_C PF08769.6 EIE79392.1 - 0.026 14.3 0.0 0.055 13.3 0.0 1.5 1 0 0 1 1 1 0 Sporulation initiation factor Spo0A C terminal SH3_3 PF08239.6 EIE79392.1 - 0.052 13.7 0.4 0.15 12.3 0.0 2.0 2 0 0 2 2 2 0 Bacterial SH3 domain RGS PF00615.14 EIE79393.1 - 1e-15 57.8 0.7 1.5e-15 57.3 0.5 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain RGS-like PF09128.6 EIE79393.1 - 5.1e-07 29.3 0.2 7.3e-07 28.8 0.1 1.2 1 0 0 1 1 1 1 Regulator of G protein signalling-like domain Pkinase PF00069.20 EIE79395.1 - 3e-59 200.2 0.0 4.5e-59 199.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE79395.1 - 2.4e-21 75.9 0.0 3.4e-21 75.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIE79395.1 - 1.7e-05 24.6 0.0 3.1e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EIE79395.1 - 0.0021 17.0 0.0 0.0078 15.2 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EIE79395.1 - 0.0075 15.3 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1687 PF07955.6 EIE79396.1 - 2.3e-10 40.5 1.4 4.1e-10 39.7 1.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1687) ArsC PF03960.10 EIE79396.1 - 3.7e-06 26.9 0.2 6.9e-06 26.1 0.1 1.6 1 1 0 1 1 1 1 ArsC family Dict-STAT-coil PF09267.5 EIE79396.1 - 0.15 12.2 1.4 0.32 11.2 0.4 1.8 1 1 1 2 2 2 0 Dictyostelium STAT, coiled coil TraL PF07178.6 EIE79397.1 - 0.0023 17.9 0.2 0.0053 16.7 0.2 1.6 1 1 0 1 1 1 1 TraL protein RolB_RolC PF02027.12 EIE79397.1 - 0.072 12.2 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 RolB/RolC glucosidase family DUF1212 PF06738.7 EIE79397.1 - 0.093 12.1 1.2 0.13 11.7 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1212) Mannosyl_trans3 PF11051.3 EIE79398.1 - 1.5e-35 122.9 1.7 1.2e-34 119.9 1.2 2.0 1 1 0 1 1 1 1 Mannosyltransferase putative DDE_3 PF13358.1 EIE79399.1 - 1e-10 41.5 0.0 1.7e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE79399.1 - 1.8e-08 34.3 0.8 3.4e-08 33.4 0.5 1.5 1 0 0 1 1 1 1 Transposase DUF950 PF06106.6 EIE79400.1 - 0.12 12.5 0.1 0.15 12.1 0.1 1.2 1 0 0 1 1 1 0 Staphylococcus protein of unknown function (DUF950) MRAP PF15183.1 EIE79401.1 - 0.14 11.7 0.3 0.77 9.4 0.0 2.1 2 0 0 2 2 2 0 Melanocortin-2 receptor accessory protein family PfUIS3 PF11567.3 EIE79404.1 - 0.0059 16.7 0.4 1.6 8.9 0.1 2.1 2 0 0 2 2 2 2 Plasmodium falciparum UIS3 membrane protein SNAPc_SNAP43 PF09808.4 EIE79404.1 - 0.021 14.5 0.1 2.9 7.5 0.0 2.1 2 0 0 2 2 2 0 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 DDE_3 PF13358.1 EIE79405.1 - 1.6e-14 53.8 0.0 2.7e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE79405.1 - 1.7e-08 34.3 0.8 3.4e-08 33.4 0.5 1.5 1 0 0 1 1 1 1 Transposase DUF950 PF06106.6 EIE79406.1 - 0.12 12.5 0.1 0.15 12.1 0.1 1.2 1 0 0 1 1 1 0 Staphylococcus protein of unknown function (DUF950) DDE_3 PF13358.1 EIE79408.1 - 3.6e-10 39.7 1.8 1.1e-08 34.9 1.0 2.3 1 1 1 2 2 2 2 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE79408.1 - 2.3e-07 30.7 0.3 5.1e-07 29.6 0.1 1.8 2 0 0 2 2 2 1 Transposase RVT_1 PF00078.22 EIE79409.1 - 2.6e-16 59.6 0.1 5.7e-16 58.5 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 EIE79409.1 - 8.5e-08 32.5 0.0 2.4e-07 31.1 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 EIE79409.1 - 3.4e-07 30.1 0.2 1.7e-06 27.8 0.0 2.3 2 0 0 2 2 2 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EIE79409.1 - 0.00041 20.1 0.0 0.001 18.8 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.12 EIE79409.1 - 0.00099 19.1 1.6 0.011 15.8 0.0 3.5 3 0 0 3 3 3 1 Retrotransposon gag protein Asp_protease PF09668.5 EIE79409.1 - 0.0059 16.1 0.6 0.014 14.9 0.1 1.8 2 0 0 2 2 2 1 Aspartyl protease PMC2NT PF08066.7 EIE79409.1 - 0.024 14.9 0.6 16 5.8 0.0 3.2 2 0 0 2 2 2 0 PMC2NT (NUC016) domain Peptidase_M3_N PF08439.5 EIE79409.1 - 0.056 13.4 1.7 0.12 12.3 0.2 2.4 2 0 0 2 2 2 0 Oligopeptidase F RVP_2 PF08284.6 EIE79409.1 - 0.069 13.0 0.1 0.25 11.2 0.0 1.9 2 0 0 2 2 2 0 Retroviral aspartyl protease DUF3479 PF11965.3 EIE79409.1 - 0.12 12.1 1.1 0.18 11.6 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3479) IncA PF04156.9 EIE79409.1 - 0.4 10.2 4.7 1.1 8.8 3.2 1.7 1 0 0 1 1 1 0 IncA protein V-SNARE PF05008.10 EIE79409.1 - 1.2 9.3 10.2 0.52 10.5 4.5 2.5 2 0 0 2 2 1 0 Vesicle transport v-SNARE protein N-terminus FlxA PF14282.1 EIE79409.1 - 1.6 8.6 8.6 1.7 8.6 3.3 2.9 2 1 0 2 2 2 0 FlxA-like protein rve PF00665.21 EIE79410.1 - 3.8e-18 65.7 0.0 8.7e-18 64.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 EIE79410.1 - 3.1e-09 36.3 1.0 6.7e-09 35.2 0.7 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 EIE79410.1 - 0.057 13.1 1.7 0.061 13.0 0.2 1.8 2 0 0 2 2 2 0 RNA binding activity-knot of a chromodomain HTH_Tnp_Tc3_2 PF01498.13 EIE79412.1 - 5.1e-11 42.4 2.6 6.1e-11 42.2 0.8 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.1 EIE79412.1 - 0.0025 17.5 0.0 0.0051 16.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 EIE79412.1 - 0.01 15.9 0.2 0.024 14.7 0.0 1.7 2 0 0 2 2 2 0 Winged helix-turn helix RecX PF02631.11 EIE79412.1 - 0.13 12.5 0.2 0.2 11.9 0.1 1.4 1 0 0 1 1 1 0 RecX family rve PF00665.21 EIE79413.1 - 6.2e-20 71.5 0.0 2.8e-19 69.3 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 EIE79413.1 - 4.1e-11 42.6 0.3 1.2e-10 41.0 0.2 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE79413.1 - 5.4e-07 29.1 2.4 1.2e-06 28.0 1.6 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.1 EIE79413.1 - 1.2e-06 28.9 0.3 1.2e-05 25.7 0.1 2.4 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.15 EIE79413.1 - 1.5e-05 24.8 0.1 4.6e-05 23.2 0.1 1.9 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EIE79413.1 - 4.2e-05 23.2 0.0 9.8e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Tudor-knot PF11717.3 EIE79413.1 - 0.0082 15.8 0.9 0.027 14.1 0.6 1.9 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Asp_protease PF09668.5 EIE79413.1 - 0.074 12.6 0.0 0.27 10.7 0.0 2.0 1 0 0 1 1 1 0 Aspartyl protease DUF3408 PF11888.3 EIE79414.1 - 0.0023 17.8 0.8 0.01 15.7 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3408) RVT_1 PF00078.22 EIE79415.1 - 7.6e-29 100.6 0.0 1.5e-28 99.6 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EIE79415.1 - 1.3e-14 53.7 0.0 3.1e-14 52.5 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RVT_1 PF00078.22 EIE79416.1 - 6e-27 94.4 0.0 9.5e-27 93.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EIE79416.1 - 6.1e-15 54.8 0.1 1.6e-14 53.5 0.0 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EIE79416.1 - 9.8e-06 25.6 0.1 3.1e-05 24.0 0.0 1.9 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family FlxA PF14282.1 EIE79416.1 - 0.44 10.5 2.7 0.81 9.6 1.8 1.4 1 0 0 1 1 1 0 FlxA-like protein Serglycin PF04360.7 EIE79416.1 - 1.2 8.9 11.3 0.013 15.2 2.3 1.9 2 0 0 2 2 2 0 Serglycin DUF3408 PF11888.3 EIE79417.1 - 0.0023 17.8 0.8 0.01 15.7 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3408) RVT_1 PF00078.22 EIE79418.1 - 7.2e-29 100.6 0.0 1.6e-28 99.5 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EIE79418.1 - 4.8e-15 55.2 0.0 1.2e-14 53.9 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase ZYG-11_interact PF05884.7 EIE79418.1 - 0.34 9.9 0.0 0.62 9.0 0.0 1.3 1 0 0 1 1 1 0 Interactor of ZYG-11 MatC_N PF07158.6 EIE79420.1 - 0.12 12.1 0.1 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Dicarboxylate carrier protein MatC N-terminus rve PF00665.21 EIE79421.1 - 1.7e-24 86.2 0.0 5.4e-24 84.5 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE79421.1 - 6.7e-17 61.5 0.0 1.3e-16 60.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 EIE79421.1 - 0.00035 21.0 0.2 0.001 19.5 0.2 1.9 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.5 EIE79421.1 - 0.0004 19.7 0.1 0.001 18.4 0.1 1.7 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger UBN2_2 PF14227.1 EIE79421.1 - 0.0051 16.3 1.8 0.074 12.6 0.0 2.9 3 0 0 3 3 3 1 gag-polypeptide of LTR copia-type rve_3 PF13683.1 EIE79421.1 - 0.013 14.9 0.0 0.04 13.4 0.0 1.9 1 0 0 1 1 1 0 Integrase core domain Asp_protease PF09668.5 EIE79421.1 - 0.092 12.3 0.1 0.26 10.8 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.1 EIE79421.1 - 0.15 11.9 0.0 0.35 10.7 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease HTH_Tnp_Tc3_2 PF01498.13 EIE79422.1 - 5.7e-19 67.9 0.7 5.7e-19 67.9 0.5 2.3 2 1 1 3 3 3 1 Transposase HTH_29 PF13551.1 EIE79422.1 - 2.4e-06 27.6 0.8 6.1e-06 26.3 0.5 1.7 1 1 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EIE79422.1 - 0.00023 20.6 0.3 0.011 15.3 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_32 PF13565.1 EIE79422.1 - 0.00026 21.7 3.4 0.00058 20.6 0.2 2.8 2 1 1 3 3 3 1 Homeodomain-like domain HTH_21 PF13276.1 EIE79422.1 - 0.02 14.8 0.2 0.57 10.2 0.0 3.0 2 1 1 3 3 3 0 HTH-like domain NUMOD3 PF07460.6 EIE79422.1 - 0.093 12.6 0.1 0.5 10.3 0.1 2.2 2 0 0 2 2 2 0 NUMOD3 motif (2 copies) HTH_Tnp_Tc3_2 PF01498.13 EIE79423.1 - 0.00028 20.8 1.8 0.0046 16.9 0.0 2.3 1 1 1 2 2 2 1 Transposase HTH_29 PF13551.1 EIE79423.1 - 0.0063 16.6 0.8 0.012 15.7 0.5 1.5 1 1 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_ISL3 PF13542.1 EIE79423.1 - 0.04 13.0 1.4 0.081 12.1 0.6 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_21 PF13276.1 EIE79423.1 - 0.06 13.3 0.4 2.2 8.3 0.0 2.3 2 0 0 2 2 2 0 HTH-like domain HTH_Tnp_1 PF01527.15 EIE79423.1 - 0.077 12.9 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Transposase zf-DBF PF07535.7 EIE79425.1 - 1.7e-15 56.4 1.5 3.1e-15 55.5 1.0 1.5 1 0 0 1 1 1 1 DBF zinc finger Dfp1_Him1_M PF08630.5 EIE79425.1 - 1.4e-06 28.1 7.8 2.7e-05 23.9 0.0 3.7 2 1 1 3 3 3 2 Dfp1/Him1, central region DUF1499 PF07386.6 EIE79427.1 - 0.0061 16.7 0.1 0.0061 16.7 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1499) OrfB_Zn_ribbon PF07282.6 EIE79429.1 - 0.00031 20.3 0.3 0.004 16.7 0.0 2.5 2 0 0 2 2 2 1 Putative transposase DNA-binding domain Fumarate_red_C PF02300.12 EIE79431.1 - 0.077 12.8 0.0 0.087 12.6 0.0 1.1 1 0 0 1 1 1 0 Fumarate reductase subunit C Pkinase PF00069.20 EIE79432.1 - 1e-58 198.5 0.0 1.2e-58 198.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE79432.1 - 1.1e-40 139.3 0.0 1.5e-40 138.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE79432.1 - 6e-05 22.1 0.0 0.00023 20.2 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.6 EIE79432.1 - 0.011 14.5 0.0 0.027 13.2 0.0 1.6 2 0 0 2 2 2 0 Seadornavirus VP7 Ras PF00071.17 EIE79433.1 - 5.9e-42 142.8 0.1 7.7e-42 142.4 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIE79433.1 - 1.2e-10 41.9 0.2 2.6e-10 40.8 0.0 1.7 2 1 0 2 2 2 1 Miro-like protein Arf PF00025.16 EIE79433.1 - 2.3e-10 40.0 0.3 3.1e-10 39.5 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EIE79433.1 - 1.9e-05 24.1 0.0 2.8e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EIE79433.1 - 0.02 14.0 0.1 0.029 13.4 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region FeoB_N PF02421.13 EIE79433.1 - 0.026 13.7 0.1 0.04 13.2 0.1 1.2 1 0 0 1 1 1 0 Ferrous iron transport protein B Metallophos PF00149.23 EIE79434.1 - 7.8e-20 71.1 0.0 2.8e-17 62.7 0.0 2.1 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase GGDEF PF00990.16 EIE79435.1 - 0.058 12.9 0.6 1.3 8.5 0.1 2.2 2 0 0 2 2 2 0 GGDEF domain DUF3877 PF12993.2 EIE79435.1 - 0.089 12.3 0.1 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3877) Histidinol_dh PF00815.15 EIE79437.1 - 1e-180 600.7 2.4 1.5e-180 600.2 1.7 1.2 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.13 EIE79437.1 - 1.4e-25 88.7 0.1 3e-25 87.6 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 EIE79437.1 - 1.4e-12 47.7 0.4 1e-11 44.9 0.0 2.7 3 0 0 3 3 3 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.12 EIE79437.1 - 0.043 13.7 0.2 0.12 12.3 0.1 1.7 1 0 0 1 1 1 0 MazG nucleotide pyrophosphohydrolase domain Molydop_binding PF01568.16 EIE79437.1 - 0.05 13.4 0.1 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain PI-PLC-X PF00388.14 EIE79438.1 - 9.8e-07 28.2 0.0 2.1e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain WD40 PF00400.27 EIE79440.1 - 6.7e-19 66.9 22.3 7.7e-05 22.4 0.0 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat zf-C3HC4_2 PF13923.1 EIE79440.1 - 3.4e-07 30.1 12.0 1.2e-06 28.4 8.3 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIE79440.1 - 8.6e-07 28.6 10.5 2.5e-06 27.1 7.3 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EIE79440.1 - 2.7e-05 23.7 12.8 2.7e-05 23.7 8.9 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EIE79440.1 - 7e-05 22.4 9.0 7e-05 22.4 6.2 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EIE79440.1 - 0.00015 21.5 12.0 0.0004 20.1 8.3 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EIE79440.1 - 0.00048 19.8 10.2 0.00048 19.8 7.1 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_6 PF14835.1 EIE79440.1 - 0.0017 18.1 3.1 0.004 16.8 2.1 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 EIE79440.1 - 0.023 14.3 8.6 0.06 13.0 5.9 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-rbx1 PF12678.2 EIE79440.1 - 0.25 11.4 7.0 1.2 9.2 4.9 2.2 1 1 0 1 1 1 0 RING-H2 zinc finger MFS_1 PF07690.11 EIE79441.1 - 0.00016 20.5 41.9 0.015 14.0 9.3 3.8 2 1 2 4 4 4 3 Major Facilitator Superfamily GHBP PF12772.2 EIE79442.1 - 0.063 12.6 0.1 0.063 12.6 0.1 1.1 1 0 0 1 1 1 0 Growth hormone receptor binding Pkinase PF00069.20 EIE79443.1 - 8.4e-61 205.3 0.1 2e-60 204.1 0.0 1.6 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE79443.1 - 2.8e-28 98.6 0.2 4.6e-28 98.0 0.1 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE79443.1 - 2e-06 27.0 0.1 5.8e-05 22.1 0.0 2.1 1 1 0 2 2 2 1 Kinase-like RIO1 PF01163.17 EIE79443.1 - 0.00014 21.3 0.2 0.00023 20.5 0.2 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 EIE79443.1 - 0.0023 16.9 0.2 0.0042 16.1 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family P16-Arc PF04699.9 EIE79444.1 - 1.2e-29 103.2 3.1 6.1e-24 84.7 0.2 2.0 1 1 1 2 2 2 2 ARP2/3 complex 16 kDa subunit (p16-Arc) UPF0020 PF01170.13 EIE79444.1 - 0.043 13.3 0.0 0.049 13.2 0.0 1.1 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Ank_4 PF13637.1 EIE79445.1 - 2.5e-27 94.7 3.4 2.2e-09 37.5 0.0 5.3 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.2 EIE79445.1 - 7.3e-21 74.3 2.6 5.5e-08 33.0 0.1 4.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EIE79445.1 - 2.6e-16 58.5 6.3 8.5e-07 28.4 0.0 4.6 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.1 EIE79445.1 - 1.2e-14 52.9 1.5 1.5e-05 24.7 0.0 4.6 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.1 EIE79445.1 - 2e-12 46.8 5.9 6.6e-07 29.3 0.1 4.9 3 2 2 5 5 5 3 Ankyrin repeats (many copies) NAD_binding_5 PF07994.7 EIE79446.1 - 1.2e-112 376.2 0.0 1.4e-112 375.9 0.0 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 EIE79446.1 - 7.1e-45 151.4 0.0 1.5e-44 150.4 0.0 1.6 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase SIS PF01380.17 EIE79446.1 - 0.077 12.6 0.0 0.95 9.0 0.0 2.4 2 0 0 2 2 2 0 SIS domain Arrestin_N PF00339.24 EIE79447.1 - 2.7e-12 46.7 0.0 4.9e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Homeobox PF00046.24 EIE79448.1 - 5.1e-21 74.0 3.0 9.3e-21 73.2 2.1 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EIE79448.1 - 0.0034 17.0 2.2 0.0073 15.9 0.2 2.3 2 0 0 2 2 2 1 Homeobox KN domain RNA_pol_I_A49 PF06870.7 EIE79448.1 - 0.021 13.3 1.0 0.032 12.8 0.2 1.6 2 0 0 2 2 2 0 A49-like RNA polymerase I associated factor Mito_fiss_reg PF05308.6 EIE79448.1 - 0.69 9.2 7.0 1 8.6 4.9 1.3 1 1 0 1 1 1 0 Mitochondrial fission regulator SMN PF06003.7 EIE79448.1 - 4 6.4 12.8 3.8 6.5 8.0 1.4 1 1 0 1 1 1 0 Survival motor neuron protein (SMN) Tubulin PF00091.20 EIE79449.1 - 6.7e-71 238.5 0.0 9.1e-71 238.0 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EIE79449.1 - 2.3e-49 166.5 0.0 3.7e-49 165.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EIE79449.1 - 0.00033 20.1 0.0 0.00057 19.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain GAS PF13851.1 EIE79450.1 - 0.031 13.4 35.9 0.17 11.0 6.2 3.2 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding HisKA_3 PF07730.8 EIE79450.1 - 1.8 8.9 8.4 4.6 7.6 1.5 3.1 2 2 0 2 2 2 0 Histidine kinase CENP-F_leu_zip PF10473.4 EIE79450.1 - 9.4 6.0 30.7 1.3 8.8 6.2 3.3 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NUDIX PF00293.23 EIE79451.1 - 9e-16 57.7 0.0 1.1e-15 57.4 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain UQ_con PF00179.21 EIE79454.1 - 2.2e-51 172.9 0.0 2.5e-51 172.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EIE79454.1 - 7.2e-06 25.7 0.0 8.9e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EIE79454.1 - 0.012 15.4 0.2 0.018 14.9 0.1 1.5 1 1 0 1 1 1 0 RWD domain UEV PF05743.8 EIE79454.1 - 0.041 13.5 0.0 0.065 12.9 0.0 1.3 1 0 0 1 1 1 0 UEV domain Ribosomal_L7Ae PF01248.21 EIE79455.1 - 5.7e-27 93.0 0.0 6.6e-27 92.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Nuclease_act PF08133.6 EIE79456.1 - 0.46 10.0 2.4 1.1 8.8 1.7 1.6 1 0 0 1 1 1 0 Anticodon nuclease activator family MitMem_reg PF13012.1 EIE79457.1 - 3.6e-41 139.8 1.3 5.6e-41 139.2 0.4 1.7 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.16 EIE79457.1 - 1.1e-20 73.5 1.6 2.2e-19 69.2 0.1 2.7 2 1 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Ras PF00071.17 EIE79458.1 - 1.1e-46 158.1 0.1 1.4e-46 157.8 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIE79458.1 - 3.7e-11 43.5 0.0 1.2e-10 41.9 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EIE79458.1 - 4e-10 39.2 0.1 5.2e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EIE79458.1 - 0.0012 18.3 0.0 0.0015 17.9 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EIE79458.1 - 0.0084 15.2 0.0 0.011 14.8 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Asp PF00026.18 EIE79459.1 - 4.8e-84 282.3 0.2 5.7e-84 282.0 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIE79459.1 - 1.3e-07 31.7 0.0 1.4e-06 28.3 0.0 2.4 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EIE79459.1 - 0.0056 17.1 0.2 1.3 9.5 0.0 2.8 2 1 0 2 2 2 2 Aspartyl protease PDEase_I PF00233.14 EIE79460.1 - 2.6e-40 138.6 0.1 7.4e-40 137.1 0.1 1.7 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.17 EIE79460.1 - 0.0017 18.3 0.0 0.0029 17.5 0.0 1.5 1 0 0 1 1 1 1 HD domain CPSF_A PF03178.10 EIE79461.1 - 1.7e-89 300.1 0.0 3.2e-87 292.6 0.1 2.7 2 1 0 2 2 2 2 CPSF A subunit region MMS1_N PF10433.4 EIE79461.1 - 5.3e-22 77.6 0.0 1.8e-21 75.8 0.0 1.9 1 1 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term D5_N PF08706.6 EIE79461.1 - 0.76 9.8 3.6 19 5.2 0.0 3.0 3 0 0 3 3 3 0 D5 N terminal like Ribosomal_S28e PF01200.13 EIE79462.1 - 3.6e-17 61.8 1.4 3.7e-17 61.8 1.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Longin PF13774.1 EIE79463.1 - 0.13 11.8 0.2 0.17 11.4 0.1 1.5 1 0 0 1 1 1 0 Regulated-SNARE-like domain Ribosomal_L16 PF00252.13 EIE79465.1 - 1e-33 115.8 0.1 1.3e-33 115.6 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e UQ_con PF00179.21 EIE79466.1 - 1.4e-17 63.4 0.2 1.7e-17 63.1 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF2084 PF09857.4 EIE79466.1 - 0.052 13.2 0.0 0.075 12.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2084) Cellulase PF00150.13 EIE79467.1 - 1.9e-20 73.2 0.2 6.1e-13 48.6 0.0 2.6 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) DSPc PF00782.15 EIE79468.1 - 1.1e-12 47.6 0.0 1.2e-12 47.5 0.0 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EIE79468.1 - 0.00057 19.3 0.0 0.0019 17.5 0.0 1.7 1 1 1 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EIE79468.1 - 0.00078 19.5 0.0 0.001 19.1 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate Init_tRNA_PT PF04179.7 EIE79468.1 - 0.0052 15.7 0.0 0.0061 15.4 0.0 1.0 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase Y_phosphatase2 PF03162.8 EIE79468.1 - 0.0061 15.9 0.0 0.0074 15.6 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family CDKN3 PF05706.7 EIE79468.1 - 0.029 13.8 0.0 0.033 13.6 0.0 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.1 EIE79468.1 - 0.041 14.1 0.0 0.046 13.9 0.0 1.3 1 1 0 1 1 1 0 Tyrosine phosphatase family Chromo PF00385.19 EIE79469.1 - 9e-08 31.6 3.4 4.1e-07 29.5 2.4 2.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain KRAP_IP3R_bind PF14722.1 EIE79469.1 - 0.054 13.0 0.5 0.054 13.0 0.4 2.1 2 0 0 2 2 2 0 Ki-ras-induced actin-interacting protein-IP3R-interacting domain Alpha-2-MRAP_N PF06400.6 EIE79469.1 - 4.5 6.9 7.4 0.13 11.8 0.7 1.7 2 0 0 2 2 2 0 Alpha-2-macroglobulin RAP, N-terminal domain E1-E2_ATPase PF00122.15 EIE79470.1 - 5.6e-60 202.2 1.0 1e-59 201.3 0.7 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EIE79470.1 - 2.3e-28 100.0 0.0 1.7e-27 97.2 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 EIE79470.1 - 4.6e-20 71.8 18.2 1.4e-15 57.2 2.4 3.3 4 0 0 4 4 4 2 Cation transporting ATPase, C-terminus Hydrolase_like2 PF13246.1 EIE79470.1 - 1.3e-19 69.9 0.0 3.1e-19 68.7 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EIE79470.1 - 3.6e-14 51.9 0.0 8.3e-14 50.8 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EIE79470.1 - 1.8e-12 47.8 0.0 3.9e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EIE79470.1 - 0.017 14.7 10.0 0.048 13.2 1.1 3.2 2 1 0 3 3 3 0 haloacid dehalogenase-like hydrolase Pkinase PF00069.20 EIE79471.1 - 3.8e-55 186.8 0.1 4.2e-55 186.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE79471.1 - 7.7e-30 103.8 0.0 9.3e-30 103.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE79471.1 - 5.1e-11 42.0 0.0 8.7e-11 41.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EIE79471.1 - 2.7e-05 23.3 0.2 5.3e-05 22.3 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EIE79471.1 - 3e-05 23.4 0.1 4.1e-05 22.9 0.1 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EIE79471.1 - 0.00013 21.7 0.1 0.00019 21.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EIE79471.1 - 0.0018 17.1 0.1 0.0022 16.8 0.1 1.1 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Choline_kinase PF01633.15 EIE79471.1 - 0.012 15.1 0.1 0.019 14.5 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase WaaY PF06176.6 EIE79471.1 - 0.015 14.5 0.1 0.028 13.6 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Seadorna_VP7 PF07387.6 EIE79471.1 - 0.038 12.8 0.0 0.076 11.8 0.0 1.5 1 0 0 1 1 1 0 Seadornavirus VP7 YrbL-PhoP_reg PF10707.4 EIE79471.1 - 0.093 12.0 0.1 0.2 10.9 0.0 1.3 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL 2-Hacid_dh_C PF02826.14 EIE79472.1 - 1.4e-50 170.9 0.0 2.6e-50 170.0 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EIE79472.1 - 3.6e-34 117.0 0.1 5e-34 116.6 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EIE79472.1 - 6.4e-05 22.8 0.8 0.00024 20.9 0.0 2.2 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Glyco_trans_4_2 PF13477.1 EIE79472.1 - 0.031 14.0 0.1 0.06 13.1 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase 4-like ACT PF01842.20 EIE79472.1 - 0.04 13.4 0.0 0.19 11.2 0.0 2.2 2 0 0 2 2 2 0 ACT domain PSDC PF12588.3 EIE79472.1 - 0.12 12.0 0.1 1.7 8.2 0.0 2.6 3 0 0 3 3 3 0 Phophatidylserine decarboxylase zf-DHHC PF01529.15 EIE79473.1 - 2.6e-20 72.5 7.4 3.1e-20 72.3 5.1 1.1 1 0 0 1 1 1 1 DHHC palmitoyltransferase HIPIP PF01355.12 EIE79473.1 - 0.34 11.0 4.5 0.53 10.4 3.1 1.3 1 0 0 1 1 1 0 High potential iron-sulfur protein GATA PF00320.22 EIE79473.1 - 0.8 9.1 6.1 3.4 7.0 4.2 2.0 1 1 0 1 1 1 0 GATA zinc finger Pribosyl_synth PF14572.1 EIE79474.1 - 1.1e-39 136.1 0.8 1.6e-33 115.9 0.3 2.2 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 EIE79474.1 - 1.9e-37 127.5 0.1 5.1e-35 119.7 0.0 2.5 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 EIE79474.1 - 1.4e-12 47.4 0.1 2.9e-12 46.3 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EIE79474.1 - 0.00088 18.5 0.2 0.0057 15.8 0.1 2.0 2 0 0 2 2 2 1 Uracil phosphoribosyltransferase PC_rep PF01851.17 EIE79475.1 - 2.1e-26 90.6 18.4 4e-06 26.7 0.2 8.2 8 0 0 8 8 8 6 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EIE79475.1 - 8.9e-05 22.7 0.8 0.92 9.8 0.1 4.3 3 0 0 3 3 3 2 HEAT repeats ubiquitin PF00240.18 EIE79476.1 - 0.0069 15.7 0.2 0.32 10.4 0.0 2.9 3 1 0 3 3 3 1 Ubiquitin family DUF2407 PF10302.4 EIE79476.1 - 0.013 15.7 0.1 0.028 14.6 0.0 1.6 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 EIE79476.1 - 0.045 13.6 0.0 0.38 10.6 0.0 2.2 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Sds3 PF08598.6 EIE79478.1 - 4.8e-14 52.3 2.9 4.8e-14 52.3 2.0 2.9 1 1 2 3 3 3 1 Sds3-like CAF-1_p150 PF11600.3 EIE79478.1 - 2.3 7.5 44.7 5 6.4 31.0 1.7 1 1 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal PIG-S PF10510.4 EIE79478.1 - 4.9 5.6 8.6 5.9 5.4 5.9 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein Ycf1 PF05758.7 EIE79478.1 - 7 4.2 18.2 8.1 4.0 12.6 1.2 1 0 0 1 1 1 0 Ycf1 Pkinase PF00069.20 EIE79479.1 - 7.1e-70 235.1 0.0 8.4e-70 234.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE79479.1 - 1.2e-32 113.0 0.0 1.5e-32 112.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE79479.1 - 8.9e-10 37.9 0.0 5.4e-08 32.1 0.0 2.1 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EIE79479.1 - 0.094 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family RhoGAP PF00620.22 EIE79480.1 - 1e-25 90.1 0.0 2.3e-25 88.9 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain MyTH4 PF00784.12 EIE79480.1 - 3.4e-24 84.9 0.0 9.5e-24 83.5 0.0 1.8 1 0 0 1 1 1 1 MyTH4 domain BTB_2 PF02214.17 EIE79480.1 - 5.4e-16 58.5 0.0 2e-15 56.7 0.0 2.1 1 0 0 1 1 1 1 BTB/POZ domain Alpha-2-MRAP_C PF06401.6 EIE79480.1 - 0.025 14.4 4.4 0.073 12.9 3.1 1.7 1 0 0 1 1 1 0 Alpha-2-macroglobulin RAP, C-terminal domain PucR PF07905.6 EIE79480.1 - 0.14 11.7 0.0 0.34 10.5 0.0 1.6 1 0 0 1 1 1 0 Purine catabolism regulatory protein-like family DUF4098 PF13345.1 EIE79481.1 - 4e-12 45.9 4.0 3e-07 30.2 1.2 2.4 1 1 0 2 2 2 2 Domain of unknown function (DUF4098) Molydop_binding PF01568.16 EIE79481.1 - 0.024 14.4 0.1 3.9 7.3 0.0 3.4 4 0 0 4 4 4 0 Molydopterin dinucleotide binding domain DUF2479 PF10651.4 EIE79481.1 - 0.1 12.1 0.1 6.4 6.2 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF2479) YabP PF07873.6 EIE79482.1 - 0.012 15.1 0.3 0.073 12.6 0.2 2.3 1 1 1 2 2 2 0 YabP family YlbD_coat PF14071.1 EIE79482.1 - 0.2 11.7 3.3 0.3 11.1 0.8 2.2 2 0 0 2 2 2 0 Putative coat protein TPR_11 PF13414.1 EIE79483.1 - 1.8e-11 43.5 17.1 0.024 14.3 0.0 6.3 6 0 0 6 6 6 4 TPR repeat TPR_16 PF13432.1 EIE79483.1 - 0.00011 22.7 1.0 13 6.5 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 EIE79483.1 - 0.0017 18.2 7.7 4.9 7.1 0.0 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.12 EIE79483.1 - 0.0047 16.7 21.4 1.2 9.1 0.1 6.7 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_9 PF13371.1 EIE79483.1 - 0.02 14.7 0.6 3.3 7.6 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.1 EIE79483.1 - 0.024 14.8 2.6 4.5 7.7 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 EIE79483.1 - 0.058 13.0 20.7 0.57 9.8 0.1 7.1 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_7 PF13176.1 EIE79483.1 - 1.2 9.0 13.4 34 4.5 0.0 6.4 5 1 0 5 5 5 0 Tetratricopeptide repeat Apc3 PF12895.2 EIE79483.1 - 5.9 7.0 10.8 1.6 8.9 0.0 4.4 6 0 0 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 CotH PF08757.6 EIE79484.1 - 1.9e-35 122.6 9.1 2.7e-35 122.1 6.3 1.2 1 0 0 1 1 1 1 CotH protein LAT PF15234.1 EIE79485.1 - 0.0024 17.3 0.9 0.0026 17.2 0.6 1.1 1 0 0 1 1 1 1 Linker for activation of T-cells Kinesin PF00225.18 EIE79487.1 - 9.4e-98 326.9 0.1 9.4e-98 326.9 0.1 2.7 3 0 0 3 3 3 1 Kinesin motor domain Apc4 PF12896.2 EIE79488.1 - 1.8e-22 79.6 0.1 3e-22 78.9 0.1 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 3-PAP PF12578.3 EIE79488.1 - 0.13 12.0 0.3 12 5.7 0.0 2.2 2 0 0 2 2 2 0 Myotubularin-associated protein Apc4_WD40 PF12894.2 EIE79489.1 - 1.3e-07 31.0 0.1 2.3e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.27 EIE79489.1 - 0.018 14.8 4.4 0.49 10.3 0.0 3.2 3 0 0 3 3 3 0 WD domain, G-beta repeat PHD PF00628.24 EIE79490.1 - 1.9e-07 30.6 13.3 1.9e-07 30.6 9.2 2.7 3 0 0 3 3 3 1 PHD-finger GATA PF00320.22 EIE79490.1 - 1.6e-05 24.1 5.3 1.6e-05 24.1 3.7 1.9 2 0 0 2 2 2 1 GATA zinc finger PHD_2 PF13831.1 EIE79490.1 - 0.00016 20.9 3.0 0.00016 20.9 2.1 2.6 2 0 0 2 2 2 1 PHD-finger zf-PHD-like PF15446.1 EIE79490.1 - 0.00052 19.3 1.9 0.00052 19.3 1.3 2.1 2 0 0 2 2 2 1 PHD/FYVE-zinc-finger like domain Tetraspannin PF00335.15 EIE79490.1 - 3.4 6.8 6.4 4.8 6.3 4.3 1.4 1 1 0 1 1 1 0 Tetraspanin family HTH_23 PF13384.1 EIE79491.1 - 4.1e-05 23.0 0.4 0.087 12.5 0.0 2.6 3 0 0 3 3 3 2 Homeodomain-like domain HTH_28 PF13518.1 EIE79491.1 - 7.2e-05 22.7 0.7 0.0065 16.4 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_29 PF13551.1 EIE79491.1 - 0.059 13.5 0.2 0.19 11.9 0.1 1.7 1 1 1 2 2 2 0 Winged helix-turn helix HTH_17 PF12728.2 EIE79491.1 - 0.16 12.2 1.4 3.9 7.7 0.0 2.3 1 1 1 2 2 2 0 Helix-turn-helix domain DDE_3 PF13358.1 EIE79495.1 - 3e-13 49.7 0.0 4.7e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF2567 PF10821.3 EIE79495.1 - 0.14 11.6 0.0 0.2 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2567) IR1-M PF12185.3 EIE79496.1 - 0.078 12.6 0.6 0.22 11.2 0.2 1.8 2 0 0 2 2 2 0 Nup358/RanBP2 E3 ligase domain DUF3408 PF11888.3 EIE79497.1 - 0.0039 17.1 0.4 0.0059 16.5 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3408) DUF1875 PF08961.5 EIE79497.1 - 0.051 12.8 0.2 0.088 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1875) Fmp27_WPPW PF10359.4 EIE79497.1 - 0.091 11.1 0.7 0.13 10.6 0.5 1.3 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain RVT_1 PF00078.22 EIE79498.1 - 4.5e-29 101.3 0.0 6.4e-29 100.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ZYG-11_interact PF05884.7 EIE79498.1 - 0.18 10.8 0.0 0.35 9.9 0.0 1.4 1 0 0 1 1 1 0 Interactor of ZYG-11 DDE_Tnp_IS1595 PF12762.2 EIE79499.1 - 2.9e-06 27.2 0.1 5.3e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 ISXO2-like transposase domain HTH_Tnp_Tc3_2 PF01498.13 EIE79500.1 - 3.1e-14 52.7 3.9 3.3e-13 49.4 0.3 2.9 3 0 0 3 3 3 1 Transposase DDE_3 PF13358.1 EIE79500.1 - 3.8e-05 23.4 2.1 0.00038 20.2 0.5 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_29 PF13551.1 EIE79500.1 - 0.08 13.0 0.7 0.87 9.7 0.1 2.3 2 1 0 2 2 2 0 Winged helix-turn helix HTH_32 PF13565.1 EIE79500.1 - 0.77 10.6 3.7 21 6.0 0.0 3.1 3 1 0 3 3 3 0 Homeodomain-like domain Transposase_21 PF02992.9 EIE79501.1 - 2.7e-14 52.7 0.0 1.1e-13 50.7 0.0 1.8 2 0 0 2 2 2 1 Transposase family tnp2 DDE_3 PF13358.1 EIE79502.1 - 9.7e-19 67.5 0.0 1.7e-18 66.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE79502.1 - 7.7e-11 41.8 0.7 3e-10 40.0 0.5 2.1 1 0 0 1 1 1 1 Transposase HTH_Tnp_4 PF13613.1 EIE79502.1 - 0.00075 18.9 0.0 0.0014 18.0 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease HTH_23 PF13384.1 EIE79502.1 - 0.0045 16.6 0.0 0.013 15.1 0.0 1.8 1 0 0 1 1 1 1 Homeodomain-like domain FAM70 PF14967.1 EIE79502.1 - 0.039 13.1 0.0 0.06 12.5 0.0 1.2 1 0 0 1 1 1 0 FAM70 protein Transposase_21 PF02992.9 EIE79503.1 - 0.0091 15.1 0.0 0.013 14.5 0.0 1.2 1 0 0 1 1 1 1 Transposase family tnp2 Rpr2 PF04032.11 EIE79504.1 - 0.054 13.3 1.4 3.9 7.4 0.1 2.4 1 1 1 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain FXa_inhibition PF14670.1 EIE79504.1 - 0.88 9.7 3.9 1.3 9.2 0.4 2.3 2 0 0 2 2 2 0 Coagulation Factor Xa inhibitory site DDE_3 PF13358.1 EIE79505.1 - 1.4e-17 63.7 0.0 2.4e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE79505.1 - 1.3e-09 37.9 0.8 5.6e-09 35.9 0.5 2.1 1 0 0 1 1 1 1 Transposase HTH_Tnp_4 PF13613.1 EIE79505.1 - 0.00076 18.9 0.0 0.0014 18.0 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease HTH_23 PF13384.1 EIE79505.1 - 0.0056 16.3 0.0 0.013 15.1 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain FAM70 PF14967.1 EIE79505.1 - 0.045 12.9 0.0 0.068 12.3 0.0 1.2 1 0 0 1 1 1 0 FAM70 protein Med15 PF09606.5 EIE79506.1 - 0.028 12.6 12.5 0.04 12.1 8.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal FlgM PF04316.8 EIE79506.1 - 2.2 8.2 5.1 13 5.8 2.9 2.3 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM Transposase_21 PF02992.9 EIE79507.1 - 6.7e-22 77.6 0.0 1.5e-21 76.5 0.0 1.5 1 0 0 1 1 1 1 Transposase family tnp2 DUF1258 PF06869.7 EIE79507.1 - 0.0025 16.9 0.0 0.0041 16.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) Retrotrans_gag PF03732.12 EIE79509.1 - 0.0027 17.7 7.8 0.0071 16.3 0.0 2.7 2 1 0 2 2 2 1 Retrotransposon gag protein rve PF00665.21 EIE79510.1 - 1.4e-26 92.9 0.0 3.1e-26 91.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 EIE79510.1 - 1.6e-05 24.3 0.0 4.1e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.5 EIE79510.1 - 0.0014 18.0 0.4 0.0033 16.7 0.3 1.7 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger DUF1759 PF03564.10 EIE79512.1 - 0.0002 21.1 0.4 0.00032 20.5 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) Asp_protease PF09668.5 EIE79513.1 - 1.5e-10 40.6 0.0 2.4e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 EIE79513.1 - 2.1e-08 34.5 0.0 5.9e-08 33.1 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.6 EIE79513.1 - 2.5e-06 27.4 0.1 6.2e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.15 EIE79513.1 - 2.6e-06 27.2 0.5 1.2e-05 25.1 0.0 2.3 2 1 1 3 3 3 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EIE79513.1 - 0.00017 21.3 0.1 0.00032 20.4 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease NOA36 PF06524.7 EIE79513.1 - 2.6 7.2 7.0 5.2 6.2 4.8 1.4 1 0 0 1 1 1 0 NOA36 protein rve PF00665.21 EIE79514.1 - 3e-07 30.5 0.3 9.4e-07 28.9 0.0 2.0 2 1 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.5 EIE79514.1 - 0.0067 15.8 1.1 0.015 14.7 0.1 2.0 2 0 0 2 2 2 1 His(2)-Cys(2) zinc finger Ice_nucleation PF00818.12 EIE79516.1 - 0.18 11.2 0.8 0.38 10.2 0.5 1.5 1 0 0 1 1 1 0 Ice nucleation protein repeat HAD PF12710.2 EIE79517.1 - 1.3e-20 74.4 0.1 5.8e-20 72.2 0.1 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EIE79517.1 - 1.8e-19 69.7 0.1 3.1e-19 68.9 0.1 1.3 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EIE79517.1 - 1.2e-16 61.8 0.1 9.5e-16 58.8 0.1 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EIE79517.1 - 1.4e-11 44.1 0.0 4e-11 42.7 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EIE79517.1 - 0.00028 20.5 0.1 0.0032 17.0 0.0 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EIE79517.1 - 0.1 12.7 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DUF3674 PF12426.3 EIE79517.1 - 0.12 11.7 0.9 7 6.1 0.1 2.5 2 0 0 2 2 2 0 RNA dependent RNA polymerase LRR_4 PF12799.2 EIE79520.1 - 0.044 13.4 0.0 0.088 12.4 0.0 1.4 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) TPR_11 PF13414.1 EIE79523.1 - 7.5e-18 63.9 16.0 6.9e-07 28.8 0.1 4.9 5 0 0 5 5 5 4 TPR repeat TPR_1 PF00515.23 EIE79523.1 - 1.6e-17 62.2 11.9 4.3e-05 22.9 0.0 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 EIE79523.1 - 9.7e-15 53.2 5.5 0.0027 17.4 0.0 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 EIE79523.1 - 2.7e-13 48.9 13.1 0.0073 16.4 0.0 7.5 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_12 PF13424.1 EIE79523.1 - 8.7e-13 48.0 8.1 7.4e-06 25.8 0.0 4.7 4 2 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.1 EIE79523.1 - 1.9e-12 46.6 0.4 0.011 15.6 0.0 5.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 EIE79523.1 - 3e-10 39.1 4.9 0.0015 18.1 0.0 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 EIE79523.1 - 3.4e-10 39.6 0.1 0.013 16.0 0.0 5.3 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EIE79523.1 - 5.1e-10 39.7 0.3 8.7e-05 23.0 0.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EIE79523.1 - 1.6e-05 24.2 0.1 0.28 11.0 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 EIE79523.1 - 0.00011 22.4 4.4 0.68 10.3 0.0 5.0 3 1 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 EIE79523.1 - 0.007 16.1 0.1 0.096 12.5 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 EIE79523.1 - 0.022 15.1 5.3 9.4 6.9 0.0 5.5 6 0 0 6 6 5 0 Tetratricopeptide repeat Gal_mutarotas_2 PF13802.1 EIE79523.1 - 0.042 13.7 0.2 0.1 12.4 0.1 1.7 1 0 0 1 1 1 0 Galactose mutarotase-like PAT1 PF09770.4 EIE79523.1 - 1.4 7.0 34.9 2.1 6.4 24.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Glyco_transf_41 PF13844.1 EIE79524.1 - 2.6e-96 322.4 3.3 1.5e-51 174.8 0.1 3.9 2 1 0 3 3 3 3 Glycosyl transferase family 41 Glyco_transf_22 PF03901.12 EIE79525.1 - 9.5e-62 209.3 27.0 1.2e-61 209.0 18.7 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family CarbpepA_inh PF02977.10 EIE79526.1 - 0.077 12.5 0.5 0.13 11.8 0.4 1.3 1 0 0 1 1 1 0 Carboxypeptidase A inhibitor RE_Eco47II PF09553.5 EIE79526.1 - 0.11 11.5 1.2 0.13 11.3 0.8 1.1 1 0 0 1 1 1 0 Eco47II restriction endonuclease AMP-binding PF00501.23 EIE79527.1 - 1.8e-45 155.0 0.0 3.6e-45 154.1 0.0 1.5 1 1 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EIE79527.1 - 2.9e-27 95.2 0.1 2.5e-22 79.0 0.0 2.9 2 1 1 3 3 3 2 Male sterility protein PP-binding PF00550.20 EIE79527.1 - 1.8e-08 34.4 0.0 3.5e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 EIE79527.1 - 0.0082 15.6 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EIE79527.1 - 0.11 11.3 0.0 0.33 9.7 0.0 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Glyco_transf_15 PF01793.11 EIE79528.1 - 1.1e-80 271.0 11.7 2.7e-52 177.7 3.4 2.1 1 1 1 2 2 2 2 Glycolipid 2-alpha-mannosyltransferase Lac_bphage_repr PF06543.7 EIE79528.1 - 0.067 12.7 0.0 0.2 11.2 0.0 1.8 1 0 0 1 1 1 0 Lactococcus bacteriophage repressor DivIC PF04977.10 EIE79529.1 - 0.034 13.6 0.1 0.088 12.2 0.1 1.7 1 0 0 1 1 1 0 Septum formation initiator DUF910 PF06014.6 EIE79529.1 - 0.083 12.8 0.1 0.45 10.4 0.0 2.2 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF910) TSC22 PF01166.13 EIE79529.1 - 0.12 12.4 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family Ribosomal_L19e PF01280.15 EIE79530.1 - 3.3e-60 202.1 10.2 3.3e-60 202.1 7.1 1.5 2 0 0 2 2 2 1 Ribosomal protein L19e Sigma54_DBD PF04552.8 EIE79530.1 - 0.31 10.5 4.9 0.66 9.4 0.1 2.5 3 0 0 3 3 3 0 Sigma-54, DNA binding domain DUF4602 PF15375.1 EIE79530.1 - 0.43 10.6 8.6 0.77 9.8 5.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4602) OmdA PF13376.1 EIE79530.1 - 2.2 8.0 6.8 0.52 9.9 0.4 2.5 1 1 1 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated FKBP_C PF00254.23 EIE79531.1 - 1.8e-29 101.6 0.0 7.1e-29 99.6 0.0 2.0 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase Utp14 PF04615.8 EIE79531.1 - 0.016 13.4 49.3 0.02 13.0 34.2 1.0 1 0 0 1 1 1 0 Utp14 protein Rtt106 PF08512.7 EIE79531.1 - 0.025 14.5 0.0 0.052 13.5 0.0 1.4 1 0 0 1 1 1 0 Histone chaperone Rttp106-like SprA-related PF12118.3 EIE79531.1 - 0.39 9.9 25.5 0.59 9.4 17.7 1.3 1 0 0 1 1 1 0 SprA-related family Mitofilin PF09731.4 EIE79531.1 - 1.4 7.4 37.7 2 6.9 26.2 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Ndc1_Nup PF09531.5 EIE79531.1 - 5.8 5.2 13.9 7.2 4.8 9.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Ribosomal_L27e PF01777.13 EIE79532.1 - 1.5e-37 127.6 7.0 2.2e-37 127.0 4.8 1.3 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 EIE79532.1 - 0.00023 20.7 3.9 0.00023 20.7 2.7 1.9 2 1 0 2 2 2 1 KOW motif HTH_32 PF13565.1 EIE79533.1 - 0.0008 20.1 0.0 0.021 15.6 0.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.1 EIE79533.1 - 0.0042 17.2 0.0 0.0087 16.1 0.0 1.5 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.1 EIE79533.1 - 0.01 15.8 0.0 0.015 15.3 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Mga PF05043.8 EIE79533.1 - 0.093 13.0 0.5 0.26 11.5 0.0 2.0 2 1 0 2 2 2 0 Mga helix-turn-helix domain RNB PF00773.14 EIE79534.1 - 1.1e-100 337.1 0.0 1.1e-100 337.1 0.0 2.4 3 0 0 3 3 3 1 RNB domain OB_RNB PF08206.6 EIE79534.1 - 0.0043 16.5 0.4 0.035 13.6 0.1 2.5 2 0 0 2 2 2 1 Ribonuclease B OB domain DUF3883 PF13020.1 EIE79535.1 - 0.025 14.3 0.3 0.059 13.1 0.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3883) DUF488 PF04343.8 EIE79535.1 - 0.054 13.8 1.7 0.08 13.3 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF488 RVT_1 PF00078.22 EIE79536.1 - 9.2e-20 70.9 0.0 4.9e-18 65.2 0.0 2.6 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.18 EIE79537.1 - 1.2e-06 28.1 13.3 0.00035 20.3 0.2 2.3 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 EIE79537.1 - 0.099 12.3 10.5 0.15 11.7 0.3 2.4 2 0 0 2 2 2 0 Zinc knuckle Exo_endo_phos_2 PF14529.1 EIE79538.1 - 1.3e-06 27.9 0.9 5e-06 26.1 0.1 2.1 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase R3H-assoc PF13902.1 EIE79538.1 - 0.043 13.7 0.4 0.088 12.7 0.1 1.6 1 1 0 1 1 1 0 R3H-associated N-terminal domain DUF2895 PF11444.3 EIE79538.1 - 0.083 12.0 0.0 1.1 8.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2895) TMF_TATA_bd PF12325.3 EIE79539.1 - 0.00022 20.9 1.2 0.00044 19.9 0.8 1.5 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding DivIVA PF05103.8 EIE79539.1 - 0.0045 17.0 3.5 0.008 16.2 2.4 1.4 1 0 0 1 1 1 1 DivIVA protein CENP-F_leu_zip PF10473.4 EIE79539.1 - 0.0066 16.3 4.1 0.011 15.5 2.9 1.4 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3450 PF11932.3 EIE79539.1 - 0.039 13.2 8.7 0.063 12.5 6.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) CCDC155 PF14662.1 EIE79539.1 - 0.044 13.3 3.3 0.092 12.3 2.3 1.5 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 Spc24 PF08286.6 EIE79539.1 - 0.045 13.4 1.5 0.1 12.3 1.0 1.8 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DUF948 PF06103.6 EIE79539.1 - 0.048 13.5 2.1 0.099 12.5 1.5 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) CCDC144C PF14915.1 EIE79539.1 - 0.048 12.5 7.7 0.067 12.1 5.4 1.2 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region APG6 PF04111.7 EIE79539.1 - 0.089 11.8 4.1 0.12 11.3 2.8 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF2999 PF11212.3 EIE79539.1 - 0.11 12.5 0.2 0.25 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2999) Filament PF00038.16 EIE79539.1 - 0.15 11.4 3.5 0.22 10.9 2.4 1.4 1 0 0 1 1 1 0 Intermediate filament protein HOOK PF05622.7 EIE79539.1 - 0.19 9.5 4.8 0.27 8.9 3.4 1.3 1 1 0 1 1 1 0 HOOK protein TPR_MLP1_2 PF07926.7 EIE79539.1 - 0.23 11.1 7.0 0.37 10.5 4.5 1.7 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DivIC PF04977.10 EIE79539.1 - 0.27 10.7 1.9 0.64 9.5 1.3 1.7 1 0 0 1 1 1 0 Septum formation initiator DUF4407 PF14362.1 EIE79539.1 - 0.31 9.9 2.8 0.36 9.7 1.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) V_ATPase_I PF01496.14 EIE79539.1 - 0.32 8.8 1.6 0.31 8.8 1.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TBPIP PF07106.8 EIE79539.1 - 0.37 10.3 6.6 0.099 12.1 1.9 2.0 2 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF972 PF06156.8 EIE79539.1 - 0.61 10.4 3.9 0.98 9.7 2.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF972) FliJ PF02050.11 EIE79539.1 - 0.62 10.1 10.1 0.038 14.0 3.2 1.8 2 0 0 2 2 2 0 Flagellar FliJ protein DUF904 PF06005.7 EIE79539.1 - 1.6 9.1 6.1 4.1 7.7 4.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF904) DUF2316 PF10078.4 EIE79539.1 - 3.2 7.7 6.6 0.23 11.4 0.8 1.9 3 0 0 3 3 2 0 Uncharacterized protein conserved in bacteria (DUF2316) DUF775 PF05603.7 EIE79539.1 - 6.4 6.2 6.8 1.8 8.0 0.0 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF775) Glyco_hydro_47 PF01532.15 EIE79540.1 - 5.3e-74 249.5 0.6 5.9e-74 249.3 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DEK_C PF08766.6 EIE79541.1 - 6.2e-07 29.1 0.1 1.8e-06 27.6 0.0 1.9 1 1 0 1 1 1 1 DEK C terminal domain Nucleo_P87 PF07267.6 EIE79541.1 - 0.68 8.5 15.3 0.72 8.4 10.6 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 SAPS PF04499.10 EIE79541.1 - 1.3 7.5 13.1 1.3 7.5 9.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Asp-B-Hydro_N PF05279.6 EIE79541.1 - 1.3 8.8 25.9 1.4 8.6 17.9 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region NARP1 PF12569.3 EIE79541.1 - 3.4 6.2 19.5 4.8 5.8 13.5 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 FLO_LFY PF01698.11 EIE79541.1 - 4.5 6.0 13.6 5.2 5.7 9.4 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein FAM60A PF15396.1 EIE79541.1 - 5.6 6.6 12.9 7.8 6.1 9.0 1.2 1 0 0 1 1 1 0 Protein Family FAM60A DUF2201_N PF13203.1 EIE79541.1 - 6.6 5.8 10.2 9.2 5.3 7.0 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain SIS PF01380.17 EIE79542.1 - 5.2e-61 204.0 0.2 5.2e-32 110.2 0.1 2.4 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 EIE79542.1 - 1.9e-26 92.6 0.1 6.6e-19 67.8 0.0 2.2 2 0 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EIE79542.1 - 1.5e-18 67.0 0.0 4.4e-18 65.5 0.0 1.7 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EIE79542.1 - 1e-13 51.1 0.0 2.1e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 EIE79542.1 - 4.9e-08 31.9 0.0 9.3e-08 31.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 EIE79542.1 - 0.00012 21.8 0.0 0.00077 19.1 0.0 2.3 2 0 0 2 2 2 1 SIS domain zf-Tim10_DDP PF02953.10 EIE79543.1 - 9.1e-08 31.2 0.3 9.3e-08 31.2 0.2 1.0 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DAHP_synth_2 PF01474.11 EIE79544.1 - 7.6e-179 594.6 0.0 2.9e-177 589.4 0.0 2.0 1 1 0 1 1 1 1 Class-II DAHP synthetase family Ins134_P3_kin PF05770.6 EIE79545.1 - 2.7e-26 92.3 0.6 3.4e-26 91.9 0.4 1.1 1 0 0 1 1 1 1 Inositol 1, 3, 4-trisphosphate 5/6-kinase ATP-grasp_4 PF13535.1 EIE79545.1 - 5.3e-06 26.2 0.0 2.8e-05 23.9 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 EIE79545.1 - 2.6e-05 23.7 0.1 0.0082 15.6 0.1 2.1 2 0 0 2 2 2 2 RimK-like ATP-grasp domain Dala_Dala_lig_C PF07478.8 EIE79545.1 - 0.00036 19.9 0.4 0.012 15.0 0.3 2.0 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EIE79545.1 - 0.0008 18.8 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain RVT_1 PF00078.22 EIE79547.1 - 5.9e-27 94.4 0.0 1.4e-26 93.2 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EIE79547.1 - 7.1e-18 64.3 2.2 2.7e-17 62.4 1.5 2.1 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EIE79547.1 - 1.2e-07 31.9 0.1 2.8e-07 30.7 0.1 1.7 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Lar_restr_allev PF14354.1 EIE79547.1 - 0.018 15.3 1.5 0.039 14.2 0.4 2.1 2 0 0 2 2 2 0 Restriction alleviation protein Lar Zn_Tnp_IS1595 PF12760.2 EIE79547.1 - 0.19 11.5 2.4 0.61 9.9 1.6 1.9 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.5 EIE79547.1 - 0.56 10.2 2.4 23 5.0 0.1 2.7 2 0 0 2 2 2 0 Zinc ribbon domain Ribosomal_S4e PF00900.15 EIE79548.1 - 6.3e-34 115.4 2.2 3.1e-33 113.2 0.6 2.3 2 0 0 2 2 2 1 Ribosomal family S4e RS4NT PF08071.7 EIE79548.1 - 1.6e-19 69.4 5.5 1.4e-18 66.4 4.6 2.0 2 0 0 2 2 2 1 RS4NT (NUC023) domain S4 PF01479.20 EIE79548.1 - 3.5e-06 26.3 0.0 7e-06 25.3 0.0 1.6 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 EIE79548.1 - 0.00034 20.2 2.7 0.00034 20.2 1.9 3.4 4 0 0 4 4 4 1 KOW motif PIF1 PF05970.9 EIE79551.1 - 7.6e-13 48.1 0.1 7.9e-13 48.0 0.1 1.0 1 0 0 1 1 1 1 PIF1-like helicase zf-RVT PF13966.1 EIE79552.1 - 3.6e-05 23.9 0.4 3.6e-05 23.9 0.3 1.7 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase Pkinase PF00069.20 EIE79553.1 - 1.6e-54 184.8 0.1 6.3e-54 182.8 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE79553.1 - 2.2e-40 138.3 0.0 7.2e-40 136.6 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase DOT1 PF08123.8 EIE79553.1 - 1.9e-32 112.2 0.1 5.5e-32 110.7 0.1 1.9 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_26 PF13659.1 EIE79553.1 - 0.00016 21.7 0.3 0.0023 17.9 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIE79553.1 - 0.00019 21.0 1.5 0.00035 20.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Kinase-like PF14531.1 EIE79553.1 - 0.001 18.0 0.0 0.0022 16.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Methyltransf_18 PF12847.2 EIE79553.1 - 0.0046 17.5 0.0 0.015 15.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIE79553.1 - 0.0069 16.8 0.1 0.031 14.7 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIE79553.1 - 0.0087 15.7 0.0 0.027 14.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIE79553.1 - 0.012 16.0 0.2 0.057 13.9 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain AdoMet_MTase PF07757.8 EIE79553.1 - 0.024 14.7 0.0 0.074 13.1 0.0 1.9 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase MetW PF07021.7 EIE79553.1 - 0.13 11.6 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Mito_carr PF00153.22 EIE79554.1 - 1e-22 79.6 0.1 1.1e-22 79.5 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial carrier protein DUF2523 PF10734.4 EIE79554.1 - 0.067 13.4 0.2 1.5 9.1 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2523) MFS_1 PF07690.11 EIE79555.1 - 4.6e-51 173.5 48.4 8.4e-34 116.8 11.5 2.0 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EIE79555.1 - 3.2e-09 35.7 35.6 1e-05 24.1 12.1 2.4 1 1 1 2 2 2 2 MFS/sugar transport protein MFS_3 PF05977.8 EIE79555.1 - 0.00032 18.9 30.9 0.034 12.2 3.6 3.1 2 1 1 3 3 3 3 Transmembrane secretion effector OATP PF03137.15 EIE79555.1 - 0.0022 16.1 13.2 0.0045 15.1 1.0 2.8 2 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family DUF2273 PF10031.4 EIE79555.1 - 0.041 13.5 0.0 0.041 13.5 0.0 4.1 4 1 0 4 4 4 0 Small integral membrane protein (DUF2273) OppC_N PF12911.2 EIE79555.1 - 0.15 11.4 4.7 11 5.4 0.2 4.3 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C DNA_pol_B PF00136.16 EIE79556.1 - 3.7e-121 405.1 1.4 3.7e-121 405.1 0.9 1.7 2 0 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EIE79556.1 - 3.1e-37 128.1 0.0 5.5e-37 127.3 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-DNA_Pol PF08996.5 EIE79556.1 - 2.1e-34 118.5 6.1 4.8e-34 117.3 4.2 1.6 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_alpha_N PF12254.3 EIE79556.1 - 1e-07 31.6 15.5 1.5e-07 31.1 7.8 2.8 2 0 0 2 2 2 1 DNA polymerase alpha subunit p180 N terminal YL1 PF05764.8 EIE79556.1 - 0.084 12.4 19.6 0.037 13.6 10.2 2.4 2 0 0 2 2 2 0 YL1 nuclear protein PAH PF02671.16 EIE79556.1 - 0.24 11.0 2.7 0.94 9.1 0.0 3.3 4 0 0 4 4 4 0 Paired amphipathic helix repeat Septin PF00735.13 EIE79557.1 - 9e-112 372.6 1.1 1.2e-111 372.2 0.7 1.1 1 0 0 1 1 1 1 Septin GTP_EFTU PF00009.22 EIE79557.1 - 1.9e-07 30.7 1.8 5.1e-06 26.0 0.0 2.5 3 1 0 3 3 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EIE79557.1 - 5.5e-07 28.9 0.1 1.4e-06 27.5 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EIE79557.1 - 2.7e-06 27.3 0.0 5.4e-06 26.3 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EIE79557.1 - 0.00011 22.6 0.4 0.00032 21.1 0.3 2.0 1 1 0 1 1 1 1 Miro-like protein AAA_22 PF13401.1 EIE79557.1 - 0.00051 20.1 0.1 0.0024 17.9 0.1 2.1 1 1 1 2 2 2 1 AAA domain AIG1 PF04548.11 EIE79557.1 - 0.0028 16.7 0.1 0.0073 15.4 0.1 1.7 1 0 0 1 1 1 1 AIG1 family AAA_33 PF13671.1 EIE79557.1 - 0.0029 17.5 0.3 0.011 15.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 EIE79557.1 - 0.0039 16.6 0.1 0.0099 15.3 0.1 1.6 1 0 0 1 1 1 1 FtsK/SpoIIIE family Sigma54_activat PF00158.21 EIE79557.1 - 0.004 16.6 0.1 0.0076 15.7 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain RNA_helicase PF00910.17 EIE79557.1 - 0.0042 17.2 0.5 0.013 15.6 0.1 2.1 2 1 0 2 2 1 1 RNA helicase AAA_18 PF13238.1 EIE79557.1 - 0.0048 17.1 1.1 0.032 14.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain IIGP PF05049.8 EIE79557.1 - 0.0068 15.2 0.2 0.016 14.0 0.1 1.6 1 1 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Dynamin_N PF00350.18 EIE79557.1 - 0.007 16.1 6.7 0.38 10.5 0.0 3.3 2 2 1 3 3 3 2 Dynamin family AAA_10 PF12846.2 EIE79557.1 - 0.0097 15.3 0.0 0.02 14.3 0.0 1.6 1 1 0 1 1 1 1 AAA-like domain Ras PF00071.17 EIE79557.1 - 0.012 14.9 0.1 0.042 13.2 0.1 1.9 1 1 0 1 1 1 0 Ras family NTPase_1 PF03266.10 EIE79557.1 - 0.014 15.0 2.2 0.65 9.6 0.4 2.5 2 0 0 2 2 2 0 NTPase ABC_tran PF00005.22 EIE79557.1 - 0.014 15.6 0.8 0.043 14.0 0.0 2.1 2 0 0 2 2 2 0 ABC transporter AAA_16 PF13191.1 EIE79557.1 - 0.021 14.8 0.6 0.11 12.5 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Pox_A32 PF04665.7 EIE79557.1 - 0.023 13.9 0.2 0.077 12.2 0.0 1.9 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_24 PF13479.1 EIE79557.1 - 0.025 14.1 0.1 0.05 13.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 EIE79557.1 - 0.039 13.4 1.3 0.81 9.1 0.1 3.1 3 1 1 4 4 4 0 Conserved hypothetical ATP binding protein NACHT PF05729.7 EIE79557.1 - 0.04 13.5 0.0 0.093 12.3 0.0 1.6 1 0 0 1 1 1 0 NACHT domain MobB PF03205.9 EIE79557.1 - 0.054 13.1 0.1 0.12 12.1 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 EIE79557.1 - 0.06 12.8 1.1 1.4 8.4 0.3 2.9 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.1 EIE79557.1 - 0.11 12.0 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SE PF00437.15 EIE79557.1 - 0.13 11.1 1.5 0.16 10.8 0.2 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein PRK PF00485.13 EIE79557.1 - 0.14 11.6 0.1 0.14 11.6 0.1 2.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.1 EIE79557.1 - 1.7 9.4 4.6 0.75 10.6 0.2 2.7 2 2 0 2 2 2 0 AAA domain Selenoprotein_S PF06936.6 EIE79557.1 - 2.1 7.8 8.2 5.2 6.5 5.6 1.6 1 1 0 1 1 1 0 Selenoprotein S (SelS) KaiC PF06745.8 EIE79557.1 - 4.5 6.3 6.1 2.3 7.2 0.1 2.8 3 0 0 3 3 3 0 KaiC APG6 PF04111.7 EIE79557.1 - 5.9 5.8 12.0 9.5 5.1 8.3 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 AAA_23 PF13476.1 EIE79557.1 - 6.8 6.9 14.4 2.1e+02 2.1 10.0 2.3 1 1 0 1 1 1 0 AAA domain PEMT PF04191.8 EIE79559.1 - 3.5e-13 49.5 1.9 3.5e-13 49.5 1.3 2.1 3 0 0 3 3 3 1 Phospholipid methyltransferase ICMT PF04140.9 EIE79559.1 - 4.1e-12 46.1 0.8 4.1e-12 46.1 0.6 2.2 2 1 1 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF1295 PF06966.7 EIE79559.1 - 4.9e-08 32.5 1.5 6e-08 32.2 1.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.11 EIE79559.1 - 0.0093 15.7 6.0 0.017 14.9 4.2 1.5 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase Glyco_hydro_3 PF00933.16 EIE79560.1 - 1.6e-85 286.6 0.0 2.3e-85 286.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EIE79560.1 - 1.8e-65 220.6 0.2 4e-65 219.5 0.1 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EIE79560.1 - 7.9e-23 80.1 0.1 1.5e-22 79.2 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF4369 PF14289.1 EIE79560.1 - 0.062 13.3 1.8 1.9 8.5 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4369) DAP PF15228.1 EIE79560.1 - 0.14 12.9 0.1 0.31 11.7 0.0 1.5 1 0 0 1 1 1 0 Death-associated protein LUC7 PF03194.10 EIE79561.1 - 3.1e-55 187.4 14.3 4.5e-55 186.9 9.9 1.2 1 0 0 1 1 1 1 LUC7 N_terminus CP12 PF02672.10 EIE79561.1 - 0.067 13.6 3.8 3.1 8.3 0.1 2.6 2 0 0 2 2 2 0 CP12 domain IncA PF04156.9 EIE79561.1 - 0.44 10.1 15.1 0.066 12.8 6.3 2.1 2 0 0 2 2 2 0 IncA protein zf-met PF12874.2 EIE79561.1 - 3.9 7.8 4.8 1.9 8.8 0.2 2.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type GCOM2 PF15328.1 EIE79562.1 - 0.032 13.9 1.9 0.039 13.7 1.0 1.4 1 1 0 1 1 1 0 Putative GRINL1B complex locus protein 2 DEAD PF00270.24 EIE79563.1 - 2.4e-45 154.0 3.8 1.3e-44 151.6 0.7 3.0 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIE79563.1 - 1.2e-27 95.5 0.7 3.3e-27 94.1 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EIE79563.1 - 8.6e-07 28.0 0.0 2e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EIE79563.1 - 2.8e-06 27.2 8.2 0.00012 21.9 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EIE79563.1 - 0.0036 17.4 0.2 0.024 14.7 0.1 2.4 2 1 0 2 2 2 1 AAA domain Helicase_C_2 PF13307.1 EIE79563.1 - 0.051 13.5 0.0 0.2 11.6 0.0 2.0 1 0 0 1 1 1 0 Helicase C-terminal domain zf-H2C2_2 PF13465.1 EIE79564.1 - 9.8e-25 85.5 35.0 1e-08 35.0 1.0 5.4 5 1 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.21 EIE79564.1 - 2.6e-22 77.7 30.4 8.8e-06 25.7 1.2 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIE79564.1 - 3.8e-11 42.4 31.0 0.0012 19.0 0.3 4.7 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EIE79564.1 - 3.7e-06 26.9 8.9 0.14 12.3 0.2 4.5 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EIE79564.1 - 0.00016 21.4 15.8 0.22 11.4 0.4 4.7 4 0 0 4 4 4 2 C2H2-type zinc finger zf-met PF12874.2 EIE79564.1 - 0.029 14.5 10.4 2.1 8.6 0.4 4.6 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-LYAR PF08790.6 EIE79564.1 - 0.56 9.9 5.6 12 5.6 0.0 3.6 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger FANCL_C PF11793.3 EIE79564.1 - 0.83 9.6 5.9 1.9 8.4 1.8 2.5 1 1 1 2 2 2 0 FANCL C-terminal domain zf-TRAF PF02176.13 EIE79564.1 - 2.9 8.3 20.7 0.37 11.2 2.6 3.5 2 1 2 4 4 4 0 TRAF-type zinc finger zf-CGNR PF11706.3 EIE79564.1 - 3.1 7.3 11.1 0.36 10.3 0.3 3.6 4 0 0 4 4 4 0 CGNR zinc finger DUF373 PF04123.8 EIE79565.1 - 0.43 9.5 9.1 0.52 9.2 6.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF373) YtpI PF14007.1 EIE79565.1 - 0.97 9.4 14.1 5.2 7.0 1.9 3.2 2 1 1 3 3 3 0 YtpI-like protein BofA PF07441.6 EIE79565.1 - 3.4 7.7 11.5 1 9.3 0.3 3.3 2 1 1 3 3 3 0 SigmaK-factor processing regulatory protein BofA DUF4418 PF14387.1 EIE79565.1 - 4.1 7.1 10.2 4.5 7.0 0.3 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4418) Asp PF00026.18 EIE79566.1 - 5.2e-40 137.6 0.0 6.2e-40 137.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIE79566.1 - 3.1e-15 56.5 0.0 3.6e-14 53.0 0.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EIE79566.1 - 1.6e-05 25.3 0.0 6.2e-05 23.4 0.0 2.0 1 1 0 1 1 1 1 Aspartyl protease Ribosomal_S24e PF01282.14 EIE79567.1 - 7.1e-36 121.8 0.4 1.1e-35 121.3 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein S24e Ribosomal_S2 PF00318.15 EIE79567.1 - 0.12 11.5 0.6 0.14 11.3 0.4 1.1 1 0 0 1 1 1 0 Ribosomal protein S2 FYVE PF01363.16 EIE79568.1 - 6.8e-07 29.0 6.7 1.4e-05 24.9 4.7 2.5 1 1 0 1 1 1 1 FYVE zinc finger HlyU PF10115.4 EIE79568.1 - 0.079 12.8 0.0 0.37 10.6 0.0 2.1 2 0 0 2 2 2 0 Transcriptional activator HlyU SR-25 PF10500.4 EIE79569.1 - 0.0001 21.8 22.4 0.0001 21.8 15.5 2.5 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein FancD2 PF14631.1 EIE79569.1 - 1.4 5.9 9.8 1.9 5.4 6.8 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease DDE_3 PF13358.1 EIE79570.1 - 1.1e-12 47.9 0.0 1.2e-12 47.8 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease Gly-zipper_YMGG PF13441.1 EIE79572.1 - 0.33 10.4 5.8 1.5 8.3 3.6 2.5 1 1 0 1 1 1 0 YMGG-like Gly-zipper RasGEF PF00617.14 EIE79573.1 - 8.7e-17 61.4 0.0 1.9e-16 60.3 0.0 1.6 1 0 0 1 1 1 1 RasGEF domain PAM2 PF07145.10 EIE79573.1 - 0.0012 18.1 1.2 0.0025 17.1 0.8 1.6 1 0 0 1 1 1 1 Ataxin-2 C-terminal region LPP20 PF02169.11 EIE79575.1 - 0.15 12.2 0.0 0.16 12.0 0.0 1.1 1 0 0 1 1 1 0 LPP20 lipoprotein DUF4329 PF14220.1 EIE79576.1 - 0.078 12.9 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4329) RhoGAP PF00620.22 EIE79577.1 - 2e-23 82.6 0.0 4.5e-23 81.5 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain ELO PF01151.13 EIE79579.1 - 4.3e-59 199.8 30.6 5.3e-59 199.5 21.2 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family T4SS-DNA_transf PF02534.9 EIE79581.1 - 0.08 11.5 0.2 0.087 11.3 0.1 1.2 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer TUG-UBL1 PF11470.3 EIE79581.1 - 0.1 12.5 0.1 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 GLUT4 regulating protein TUG DUF342 PF03961.8 EIE79581.1 - 0.23 9.8 2.3 0.29 9.5 1.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Pkinase PF00069.20 EIE79582.1 - 6.1e-71 238.6 0.7 1.1e-70 237.8 0.5 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE79582.1 - 1.2e-42 145.8 0.1 2.1e-42 145.0 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE79582.1 - 3e-06 26.4 0.0 5.6e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EIE79582.1 - 0.0015 18.2 0.1 0.0028 17.4 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EIE79582.1 - 0.019 14.0 0.6 0.036 13.1 0.4 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family AAA PF00004.24 EIE79583.1 - 1.1e-42 145.3 0.3 8.2e-41 139.2 0.0 3.3 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EIE79583.1 - 4.1e-05 23.7 1.8 0.0047 17.0 0.0 3.9 2 1 1 3 3 2 1 AAA domain AAA_5 PF07728.9 EIE79583.1 - 0.00012 21.7 2.3 0.00072 19.3 0.1 3.4 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 EIE79583.1 - 0.00014 20.7 0.0 0.00049 18.9 0.0 1.9 1 1 1 2 2 2 1 TIP49 C-terminus RuvB_N PF05496.7 EIE79583.1 - 0.00014 21.0 0.0 0.00039 19.5 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EIE79583.1 - 0.00019 22.2 2.7 0.0011 19.7 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_11 PF13086.1 EIE79583.1 - 0.00021 20.9 8.9 0.0038 16.8 0.0 2.8 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.12 EIE79583.1 - 0.0005 19.5 0.0 0.0038 16.6 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_25 PF13481.1 EIE79583.1 - 0.00062 19.2 0.5 0.14 11.5 0.2 3.2 2 1 0 3 3 3 1 AAA domain AAA_14 PF13173.1 EIE79583.1 - 0.00091 19.1 0.0 0.0052 16.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EIE79583.1 - 0.00098 19.1 4.0 0.072 13.0 1.1 3.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 EIE79583.1 - 0.0014 18.5 0.0 0.0034 17.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EIE79583.1 - 0.002 18.2 0.2 0.012 15.7 0.0 2.6 3 0 0 3 3 2 1 RNA helicase Mg_chelatase PF01078.16 EIE79583.1 - 0.0023 17.1 0.0 0.0065 15.6 0.0 1.9 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_10 PF12846.2 EIE79583.1 - 0.0027 17.1 2.4 0.48 9.8 0.1 3.2 3 1 1 4 4 4 1 AAA-like domain Sigma54_activ_2 PF14532.1 EIE79583.1 - 0.0067 16.4 0.0 0.1 12.6 0.0 2.9 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_28 PF13521.1 EIE79583.1 - 0.0074 16.2 0.8 0.022 14.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EIE79583.1 - 0.008 15.9 0.0 0.026 14.2 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 EIE79583.1 - 0.0092 16.2 0.0 0.0092 16.2 0.0 3.0 2 1 0 2 2 1 1 AAA domain ATP-synt_ab PF00006.20 EIE79583.1 - 0.022 14.2 0.0 0.049 13.1 0.0 1.5 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain NACHT PF05729.7 EIE79583.1 - 0.027 14.1 0.0 0.12 12.0 0.0 2.2 1 1 0 1 1 1 0 NACHT domain Mem_trans PF03547.13 EIE79583.1 - 0.044 12.0 0.4 0.051 11.8 0.3 1.3 1 0 0 1 1 1 0 Membrane transport protein RNA_pol_3_Rpc31 PF11705.3 EIE79583.1 - 0.05 13.5 17.9 0.1 12.4 12.4 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 ABC_tran PF00005.22 EIE79583.1 - 0.056 13.7 2.8 0.38 11.0 0.0 3.0 3 1 0 3 3 3 0 ABC transporter TRAP_alpha PF03896.11 EIE79583.1 - 0.34 9.8 9.4 0.53 9.2 6.5 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Sporozoite_P67 PF05642.6 EIE79583.1 - 0.57 7.9 12.1 0.89 7.3 8.4 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Myc_N PF01056.13 EIE79583.1 - 5.3 6.1 14.3 9.5 5.2 9.9 1.4 1 0 0 1 1 1 0 Myc amino-terminal region Nucleoplasmin PF03066.10 EIE79583.1 - 7.3 6.0 19.2 21 4.5 13.3 1.7 1 0 0 1 1 1 0 Nucleoplasmin CENP-B_dimeris PF09026.5 EIE79583.1 - 9.3 6.5 17.5 25 5.1 12.1 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain AcetylCoA_hydro PF02550.10 EIE79584.1 - 5e-51 173.2 0.0 7.2e-51 172.7 0.0 1.2 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.1 EIE79584.1 - 2e-38 131.4 0.0 2.9e-38 130.9 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain CoA_trans PF01144.18 EIE79584.1 - 0.066 12.3 0.0 0.16 11.1 0.0 1.6 2 0 0 2 2 2 0 Coenzyme A transferase AA_permease_2 PF13520.1 EIE79585.1 - 5.9e-45 153.5 35.4 7.2e-45 153.2 24.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EIE79585.1 - 2.7e-22 78.7 29.2 3.4e-22 78.4 20.3 1.0 1 0 0 1 1 1 1 Amino acid permease FeoB_C PF07664.7 EIE79585.1 - 9.3 5.7 11.4 11 5.5 0.2 4.1 3 0 0 3 3 3 0 Ferrous iron transport protein B C terminus PLDc PF00614.17 EIE79586.1 - 1.7e-11 43.5 0.9 3.1e-08 33.1 0.1 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif PX PF00787.19 EIE79586.1 - 4.4e-10 39.3 0.1 1.3e-09 37.8 0.0 1.9 2 0 0 2 2 2 1 PX domain PLDc_2 PF13091.1 EIE79586.1 - 9.4e-06 25.3 3.0 0.1 12.3 2.2 3.0 2 1 0 2 2 2 2 PLD-like domain PH PF00169.24 EIE79586.1 - 0.0013 18.9 0.3 0.004 17.3 0.2 1.9 1 1 0 1 1 1 1 PH domain HMG-CoA_red PF00368.13 EIE79587.1 - 3.5e-167 555.7 6.5 4.3e-167 555.4 4.5 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase PEX11 PF05648.9 EIE79587.1 - 0.04 13.1 0.0 0.082 12.1 0.0 1.4 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) PYST-C1 PF09690.5 EIE79588.1 - 0.0096 15.5 0.5 0.016 14.8 0.4 1.5 1 0 0 1 1 1 1 Plasmodium yoelii subtelomeric region (PYST-C1) EmrE PF13536.1 EIE79589.1 - 0.09 12.9 0.6 0.11 12.7 0.4 1.2 1 0 0 1 1 1 0 Multidrug resistance efflux transporter Neur_chan_memb PF02932.11 EIE79590.1 - 0.32 10.8 4.7 0.58 10.0 3.3 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region POX PF07526.6 EIE79590.1 - 4.8 7.4 10.5 1.7 8.8 1.4 2.5 1 1 1 2 2 2 0 Associated with HOX LMBR1 PF04791.11 EIE79590.1 - 6.8 5.1 7.7 7.8 4.9 4.8 1.4 1 1 0 1 1 1 0 LMBR1-like membrane protein Pectate_lyase_3 PF12708.2 EIE79591.1 - 0.0081 16.2 2.3 1.9 8.5 0.4 2.1 1 1 1 2 2 2 2 Pectate lyase superfamily protein IncA PF04156.9 EIE79592.1 - 0.0061 16.1 0.0 0.0061 16.1 0.0 1.1 1 0 0 1 1 1 1 IncA protein zf-DHHC PF01529.15 EIE79593.1 - 0.0017 17.7 6.4 0.038 13.4 1.4 2.3 1 1 1 2 2 2 2 DHHC palmitoyltransferase ATP-sulfurylase PF01747.12 EIE79594.1 - 4.3e-86 287.6 0.2 5.9e-86 287.2 0.1 1.2 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.1 EIE79594.1 - 5.1e-56 188.5 0.0 8.3e-56 187.8 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain APS_kinase PF01583.15 EIE79594.1 - 1.3e-51 174.3 0.0 4.2e-51 172.7 0.0 1.8 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_33 PF13671.1 EIE79594.1 - 2.3e-05 24.3 0.4 4.9e-05 23.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EIE79594.1 - 9.1e-05 22.7 0.0 0.0002 21.6 0.0 1.6 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.5 EIE79594.1 - 0.00048 19.4 0.0 0.00085 18.6 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 CPT PF07931.7 EIE79594.1 - 0.054 13.1 0.1 0.27 10.8 0.1 2.1 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein DUF3251 PF11622.3 EIE79594.1 - 0.12 11.8 0.0 0.24 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) Arrestin_N PF00339.24 EIE79596.1 - 2.6e-05 24.0 0.0 0.0001 22.1 0.0 2.0 1 1 1 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Peptidase_S8 PF00082.17 EIE79597.1 - 3.6e-54 183.8 0.4 6.3e-54 183.0 0.0 1.7 2 0 0 2 2 2 1 Subtilase family TPPII PF12580.3 EIE79597.1 - 9.8e-37 126.1 0.1 1.5e-36 125.5 0.1 1.3 1 0 0 1 1 1 1 Tripeptidyl peptidase II Pkinase PF00069.20 EIE79599.1 - 9e-66 221.6 0.1 1.8e-65 220.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE79599.1 - 6.3e-33 113.9 0.1 2.2e-32 112.1 0.1 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE79599.1 - 1.1e-08 34.4 0.0 1.7e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like KA1 PF02149.14 EIE79599.1 - 4.5e-06 25.9 0.1 1.1e-05 24.8 0.0 1.7 2 0 0 2 2 2 1 Kinase associated domain 1 Kdo PF06293.9 EIE79599.1 - 0.0044 16.1 0.3 0.0088 15.1 0.2 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EIE79599.1 - 0.01 15.2 2.0 0.013 14.8 0.3 1.9 2 0 0 2 2 2 0 RIO1 family APH PF01636.18 EIE79599.1 - 0.023 14.4 0.1 0.064 12.9 0.1 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Phage_tube PF04985.9 EIE79600.1 - 0.097 12.1 0.2 0.16 11.4 0.1 1.3 1 0 0 1 1 1 0 Phage tail tube protein FII PAT1 PF09770.4 EIE79600.1 - 0.14 10.4 15.1 0.18 10.0 10.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pex14_N PF04695.8 EIE79600.1 - 0.79 9.7 19.8 0.065 13.2 2.4 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pkinase PF00069.20 EIE79602.1 - 5.9e-08 32.1 0.0 1.1e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE79602.1 - 0.0014 17.7 0.0 0.0022 17.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PAM2 PF07145.10 EIE79602.1 - 0.007 15.7 0.2 0.026 13.9 0.2 2.0 1 0 0 1 1 1 1 Ataxin-2 C-terminal region zf-CCCH PF00642.19 EIE79602.1 - 0.15 11.8 1.4 0.36 10.5 1.0 1.6 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Pkinase PF00069.20 EIE79603.1 - 9.2e-66 221.6 0.0 1.3e-65 221.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE79603.1 - 5.4e-42 143.6 0.0 8.3e-42 143.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 EIE79603.1 - 6.6e-13 48.8 0.1 7.5e-06 26.2 0.0 2.8 2 0 0 2 2 2 2 P21-Rho-binding domain Kinase-like PF14531.1 EIE79603.1 - 1.2e-06 27.7 0.0 2.6e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EIE79603.1 - 0.0009 18.3 0.6 0.0015 17.6 0.4 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIE79603.1 - 0.014 15.1 0.4 0.025 14.3 0.3 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family HTH_Tnp_Tc3_2 PF01498.13 EIE79604.1 - 0.0011 19.0 1.3 0.0073 16.3 0.0 2.9 4 0 0 4 4 4 1 Transposase HTH_29 PF13551.1 EIE79604.1 - 0.049 13.7 0.1 0.14 12.2 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn helix ASCH PF04266.9 EIE79607.1 - 0.31 11.4 3.4 3.4 8.1 0.1 2.2 1 1 1 2 2 2 0 ASCH domain Lsr2 PF11774.3 EIE79607.1 - 4 7.3 5.4 0.34 10.8 0.4 1.7 2 0 0 2 2 2 0 Lsr2 Arb1 PF09692.5 EIE79608.1 - 6.9e-48 163.4 1.1 1.7e-41 142.3 0.2 2.1 1 1 1 2 2 2 2 Argonaute siRNA chaperone (ARC) complex subunit Arb1 Lipase_3 PF01764.20 EIE79609.1 - 6.6e-15 54.9 0.0 1.4e-14 53.8 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_1 PF00561.15 EIE79609.1 - 0.0019 17.8 0.0 0.098 12.1 0.0 2.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIE79609.1 - 0.026 14.2 0.0 0.044 13.5 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIE79609.1 - 0.031 14.1 0.0 0.047 13.5 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family PAF-AH_p_II PF03403.8 EIE79609.1 - 0.036 12.3 0.0 0.036 12.3 0.0 1.8 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II DUF2408 PF10303.4 EIE79610.1 - 1.5e-23 83.4 0.4 4.3e-11 43.0 0.2 3.0 2 1 1 3 3 3 3 Protein of unknown function (DUF2408) COG5 PF10392.4 EIE79610.1 - 0.11 12.4 0.2 0.19 11.7 0.1 1.4 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Ribosom_S12_S23 PF00164.20 EIE79613.1 - 3.2e-41 139.5 0.7 3.7e-41 139.3 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 ComX PF05952.7 EIE79614.1 - 0.056 12.9 0.0 0.098 12.1 0.0 1.4 1 0 0 1 1 1 0 Bacillus competence pheromone ComX FA_desaturase PF00487.19 EIE79615.1 - 0.022 14.2 0.0 0.022 14.2 0.0 1.0 1 0 0 1 1 1 0 Fatty acid desaturase HTH_29 PF13551.1 EIE79616.1 - 2e-08 34.3 0.0 3.5e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.1 EIE79616.1 - 2.8e-08 33.6 0.2 5.9e-06 26.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_32 PF13565.1 EIE79616.1 - 1e-07 32.6 0.0 1.8e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_23 PF13384.1 EIE79616.1 - 1.4e-06 27.7 0.4 0.00034 20.1 0.2 2.4 2 0 0 2 2 2 2 Homeodomain-like domain HTH_17 PF12728.2 EIE79616.1 - 0.00021 21.4 0.2 0.48 10.7 0.1 2.4 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_Tnp_1 PF01527.15 EIE79616.1 - 0.0061 16.4 0.1 0.016 15.1 0.0 1.6 1 1 1 2 2 2 1 Transposase HTH_30 PF13556.1 EIE79616.1 - 0.068 12.7 0.1 0.23 11.1 0.0 1.8 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain HTH_8 PF02954.14 EIE79616.1 - 0.095 12.2 0.3 1.8 8.1 0.1 2.3 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family LZ_Tnp_IS481 PF13011.1 EIE79616.1 - 0.13 12.6 0.1 0.43 10.9 0.0 1.8 2 0 0 2 2 2 0 leucine-zipper of insertion element IS481 DnaJ PF00226.26 EIE79617.1 - 1.9e-28 98.0 1.6 2.8e-28 97.4 1.1 1.3 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.1 EIE79617.1 - 0.034 13.5 0.0 0.081 12.3 0.0 1.6 1 1 1 2 2 2 0 A repeated domain in UCH-protein tRNA-synt_1c PF00749.16 EIE79618.1 - 1.5e-108 362.1 0.0 2.1e-108 361.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EIE79618.1 - 1e-40 139.2 1.9 2.4e-40 138.0 0.4 2.3 3 0 0 3 3 3 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 EIE79618.1 - 1e-07 32.3 0.1 2.7e-07 30.9 0.1 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.14 EIE79618.1 - 0.018 14.1 0.0 0.036 13.1 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain GST_C_2 PF13410.1 EIE79618.1 - 0.036 13.9 0.0 0.08 12.8 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF726 PF05277.7 EIE79619.1 - 1.8e-126 421.6 0.9 2.9e-126 421.0 0.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_5 PF12695.2 EIE79619.1 - 0.0074 16.0 0.0 0.031 14.0 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIE79619.1 - 0.04 13.4 0.0 0.084 12.4 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EIE79619.1 - 0.14 11.9 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF3020 PF11223.3 EIE79620.1 - 3.9e-20 71.9 14.3 3.9e-20 71.9 9.9 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3020) MRP-S33 PF08293.6 EIE79621.1 - 7.4e-30 102.7 0.1 9.1e-30 102.4 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 RHH_1 PF01402.16 EIE79621.1 - 0.077 12.9 0.8 0.14 12.0 0.5 1.4 1 0 0 1 1 1 0 Ribbon-helix-helix protein, copG family GATA PF00320.22 EIE79622.1 - 2.3e-05 23.6 1.2 4.1e-05 22.8 0.8 1.4 1 0 0 1 1 1 1 GATA zinc finger Cut8_M PF14483.1 EIE79623.1 - 0.00029 20.5 0.2 0.0009 18.9 0.0 2.0 3 0 0 3 3 3 1 Cut8 dimerisation domain PNRC PF15365.1 EIE79625.1 - 6.1e-15 54.9 0.1 6.1e-15 54.9 0.1 2.8 2 1 0 2 2 2 1 Proline-rich nuclear receptor coactivator SR-25 PF10500.4 EIE79625.1 - 0.0047 16.4 18.2 0.006 16.0 12.6 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein TFIIF_alpha PF05793.7 EIE79625.1 - 0.0074 14.7 3.7 0.0083 14.5 2.6 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Macoilin PF09726.4 EIE79625.1 - 0.41 8.8 9.2 0.38 8.9 6.3 1.0 1 0 0 1 1 1 0 Transmembrane protein FAM60A PF15396.1 EIE79625.1 - 1.6 8.4 9.4 2.1 8.0 6.5 1.2 1 0 0 1 1 1 0 Protein Family FAM60A DUF4642 PF15484.1 EIE79625.1 - 1.6 8.6 9.1 2.4 8.1 6.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4642) Spc7_N PF15402.1 EIE79625.1 - 4.8 5.0 13.7 6.1 4.7 9.5 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 DUF3446 PF11928.3 EIE79625.1 - 6.1 7.1 11.1 10 6.4 7.2 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3446) Pap_E4 PF02711.9 EIE79625.1 - 7.2 7.5 9.3 7.8 7.3 5.6 1.7 1 1 0 1 1 1 0 E4 protein CAP_GLY PF01302.20 EIE79626.1 - 5.1e-20 70.9 0.1 8.1e-20 70.3 0.0 1.3 1 0 0 1 1 1 1 CAP-Gly domain HOOK PF05622.7 EIE79626.1 - 0.00096 17.0 40.3 0.00096 17.0 28.0 3.6 1 1 2 3 3 3 1 HOOK protein Cofilin_ADF PF00241.15 EIE79627.1 - 1.3e-08 34.7 0.0 3.5e-08 33.3 0.0 1.8 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein PH PF00169.24 EIE79627.1 - 1.2e-06 28.6 0.0 4e-06 26.9 0.0 1.9 1 0 0 1 1 1 1 PH domain CAF-1_p150 PF11600.3 EIE79627.1 - 0.013 14.8 58.2 0.021 14.2 40.3 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Asp-B-Hydro_N PF05279.6 EIE79627.1 - 0.23 11.2 37.1 0.33 10.7 25.7 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region LMBR1 PF04791.11 EIE79627.1 - 7.6 4.9 8.3 11 4.4 5.8 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Mg_trans_NIPA PF05653.9 EIE79628.1 - 1.2e-29 103.2 13.6 1.4e-29 103.0 9.5 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA Polysacc_synt PF01943.12 EIE79628.1 - 0.057 12.6 10.8 0.074 12.3 7.5 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein HPP PF04982.8 EIE79628.1 - 0.12 12.1 1.8 0.46 10.3 0.1 2.1 1 1 1 2 2 2 0 HPP family FixH PF05751.6 EIE79628.1 - 0.41 10.4 3.5 0.87 9.3 2.4 1.5 1 0 0 1 1 1 0 FixH DUF1129 PF06570.6 EIE79628.1 - 4.1 6.6 7.6 6.8 5.9 5.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) EamA PF00892.15 EIE79628.1 - 5 7.1 13.0 9.3 6.3 9.0 1.5 1 1 0 1 1 1 0 EamA-like transporter family Got1 PF04178.7 EIE79628.1 - 5 7.2 13.1 33 4.5 9.1 2.1 1 1 0 1 1 1 0 Got1/Sft2-like family PH PF00169.24 EIE79630.1 - 2.1e-08 34.3 0.2 8.2e-08 32.3 0.1 2.1 1 0 0 1 1 1 1 PH domain LRR_6 PF13516.1 EIE79630.1 - 1.8e-07 30.4 8.5 0.059 13.4 0.4 7.7 8 0 0 8 8 8 1 Leucine Rich repeat LRR_1 PF00560.28 EIE79630.1 - 0.00029 20.4 3.1 61 4.2 0.0 7.1 7 0 0 7 7 7 0 Leucine Rich Repeat Glyco_transf_49 PF13896.1 EIE79630.1 - 0.0005 19.2 0.1 0.0011 18.0 0.1 1.5 1 0 0 1 1 1 1 Glycosyl-transferase for dystroglycan LRR_7 PF13504.1 EIE79630.1 - 0.0034 17.3 3.1 67 4.3 0.0 6.7 7 0 0 7 7 7 0 Leucine rich repeat DUF1084 PF06454.6 EIE79630.1 - 0.041 12.9 0.1 0.089 11.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1084) LRR_4 PF12799.2 EIE79630.1 - 0.093 12.3 12.4 0.33 10.6 0.0 5.3 5 1 0 6 6 6 0 Leucine Rich repeats (2 copies) Peptidase_M16 PF00675.15 EIE79631.1 - 2.8e-54 182.9 0.3 1.7e-53 180.3 0.1 2.5 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EIE79631.1 - 1.3e-44 152.1 0.0 3.8e-44 150.5 0.0 1.8 2 0 0 2 2 2 1 Peptidase M16 inactive domain BioT2 PF15368.1 EIE79632.1 - 0.0042 16.8 0.0 0.29 10.8 0.1 2.1 2 0 0 2 2 2 2 Spermatogenesis family BioT2 Peptidase_C15 PF01470.12 EIE79632.1 - 0.037 13.8 0.0 0.28 11.0 0.0 2.0 2 0 0 2 2 2 0 Pyroglutamyl peptidase DUF1827 PF08860.5 EIE79632.1 - 0.12 12.5 0.1 0.18 11.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1827) Ssl1 PF04056.9 EIE79635.1 - 2.3e-78 262.2 0.0 3.1e-78 261.7 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.7 EIE79635.1 - 2.2e-10 40.3 8.2 2.2e-10 40.3 5.7 2.5 2 0 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.1 EIE79635.1 - 2.4e-10 40.7 0.0 3.5e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain IBR PF01485.16 EIE79635.1 - 0.0035 17.1 3.1 0.0035 17.1 2.1 2.5 2 0 0 2 2 2 1 IBR domain Tfb4 PF03850.9 EIE79635.1 - 0.0046 16.2 1.1 0.0074 15.5 0.7 1.3 1 0 0 1 1 1 1 Transcription factor Tfb4 VWA PF00092.23 EIE79635.1 - 0.027 14.2 0.0 0.053 13.2 0.0 1.5 1 0 0 1 1 1 0 von Willebrand factor type A domain zf-AN1 PF01428.11 EIE79635.1 - 0.068 13.0 14.5 0.098 12.5 0.5 3.1 2 1 1 3 3 3 0 AN1-like Zinc finger Ku_N PF03731.10 EIE79635.1 - 0.11 11.8 0.6 4.4 6.6 0.0 2.5 3 0 0 3 3 3 0 Ku70/Ku80 N-terminal alpha/beta domain zf-RING_4 PF14570.1 EIE79635.1 - 4.1 7.0 12.2 7.1 6.3 2.8 2.6 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-HIT PF04438.11 EIE79635.1 - 7.7 6.2 17.3 1.7 8.3 3.1 2.8 3 0 0 3 3 3 0 HIT zinc finger DZR PF12773.2 EIE79635.1 - 8.6 6.2 20.4 4.2 7.2 4.2 2.7 2 1 0 2 2 2 0 Double zinc ribbon Pkinase PF00069.20 EIE79636.1 - 1e-29 103.4 0.2 1.4e-16 60.4 0.0 2.8 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIE79636.1 - 4.3e-08 32.5 0.1 0.00067 18.8 0.1 2.4 1 1 1 2 2 2 2 Protein tyrosine kinase Bestrophin PF01062.16 EIE79637.1 - 9.5e-56 188.8 2.3 6.8e-34 117.1 0.1 2.0 1 1 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel Zn_clus PF00172.13 EIE79638.1 - 4.6e-16 58.4 25.9 7.3e-10 38.5 6.4 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4551 PF15087.1 EIE79638.1 - 0.54 8.5 18.0 0.82 7.9 12.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Dickkopf_N PF04706.7 EIE79638.1 - 6.8 6.9 18.0 7.4 6.8 3.1 2.7 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region Rad51 PF08423.6 EIE79639.1 - 1.4e-133 443.6 0.2 1.8e-133 443.2 0.2 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EIE79639.1 - 1.9e-10 40.4 0.0 3.5e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 EIE79639.1 - 2.3e-10 40.0 0.1 3.4e-10 39.5 0.1 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 EIE79639.1 - 5.4e-08 32.2 0.3 1.4e-07 30.8 0.0 1.9 2 1 0 2 2 2 1 KaiC HHH_5 PF14520.1 EIE79639.1 - 9.5e-08 32.0 0.0 3e-07 30.5 0.0 1.8 1 1 1 2 2 2 1 Helix-hairpin-helix domain PAXNEB PF05625.6 EIE79639.1 - 0.0068 15.2 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 PAXNEB protein GvpD PF07088.6 EIE79639.1 - 0.067 11.4 0.0 0.13 10.5 0.0 1.4 1 0 0 1 1 1 0 GvpD gas vesicle protein HK PF02110.10 EIE79639.1 - 0.1 11.7 0.2 4.6 6.3 0.0 2.1 2 0 0 2 2 2 0 Hydroxyethylthiazole kinase family CLASP_N PF12348.3 EIE79640.1 - 3.3e-44 150.9 0.4 5.6e-44 150.1 0.3 1.3 1 0 0 1 1 1 1 CLASP N terminal NACHT PF05729.7 EIE79642.1 - 0.015 14.9 0.3 0.039 13.6 0.2 1.7 1 0 0 1 1 1 0 NACHT domain ATE_N PF04376.8 EIE79642.1 - 0.11 12.3 0.0 0.72 9.6 0.0 2.2 2 0 0 2 2 2 0 Arginine-tRNA-protein transferase, N terminus mRNA_cap_C PF03919.10 EIE79642.1 - 2.2 8.6 8.3 0.28 11.5 0.2 2.9 3 0 0 3 3 3 0 mRNA capping enzyme, C-terminal domain Macoilin PF09726.4 EIE79643.1 - 0.0027 16.0 37.3 0.004 15.5 25.8 1.2 1 0 0 1 1 1 1 Transmembrane protein MIP-T3 PF10243.4 EIE79643.1 - 1.1 7.5 20.0 1.5 7.2 13.9 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Mem_trans PF03547.13 EIE79643.1 - 3.8 5.7 12.3 5 5.3 8.5 1.3 1 0 0 1 1 1 0 Membrane transport protein FHA PF00498.21 EIE79644.1 - 4.8e-16 58.6 0.4 4.8e-16 58.6 0.3 1.7 2 0 0 2 2 2 1 FHA domain zf-RING_2 PF13639.1 EIE79644.1 - 3.8e-09 36.2 8.0 6.6e-09 35.4 5.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EIE79644.1 - 2.4e-05 24.3 3.9 6.2e-05 23.0 2.7 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EIE79644.1 - 0.00011 21.8 6.5 0.0002 20.9 4.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EIE79644.1 - 0.00018 21.0 6.5 0.00036 20.1 4.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EIE79644.1 - 0.00052 19.6 4.0 0.00099 18.7 2.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIE79644.1 - 0.0017 18.3 8.9 0.0031 17.4 6.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 EIE79644.1 - 0.027 14.1 3.9 0.051 13.2 2.7 1.5 1 0 0 1 1 1 0 PHD-finger zf-Apc11 PF12861.2 EIE79644.1 - 0.07 12.9 0.7 0.15 11.8 0.5 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.3 EIE79644.1 - 3.1 7.3 5.8 5.5 6.5 2.6 2.2 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Dynamin_M PF01031.15 EIE79645.1 - 9.4e-87 290.5 1.0 4.4e-69 232.5 0.0 3.3 3 1 2 5 5 5 2 Dynamin central region Dynamin_N PF00350.18 EIE79645.1 - 1.4e-53 181.1 1.5 3.6e-53 179.8 0.0 2.3 2 0 0 2 2 2 1 Dynamin family GED PF02212.13 EIE79645.1 - 4.4e-28 97.0 4.9 9.2e-28 95.9 1.4 2.7 2 0 0 2 2 2 1 Dynamin GTPase effector domain Porphobil_deam PF01379.15 EIE79645.1 - 5.4e-11 41.8 0.0 1.5e-10 40.3 0.0 1.7 1 1 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain MMR_HSR1 PF01926.18 EIE79645.1 - 0.015 15.2 0.1 0.055 13.4 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase Miro PF08477.8 EIE79645.1 - 0.037 14.5 0.1 0.17 12.4 0.0 2.1 2 0 0 2 2 2 0 Miro-like protein AAA_16 PF13191.1 EIE79645.1 - 0.038 13.9 0.0 0.14 12.1 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain DEAD PF00270.24 EIE79647.1 - 3.7e-23 81.8 0.2 5.8e-22 77.9 0.0 2.8 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIE79647.1 - 1.7e-21 75.8 0.1 1.8e-20 72.5 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain RQC PF09382.5 EIE79647.1 - 2e-19 69.2 0.3 6.3e-19 67.6 0.0 2.1 2 0 0 2 2 2 1 RQC domain ResIII PF04851.10 EIE79647.1 - 1.9e-05 24.5 0.0 6.5e-05 22.8 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 EIE79647.1 - 5.6e-05 22.5 0.0 0.00015 21.1 0.0 1.7 1 1 0 1 1 1 1 SecA DEAD-like domain Seryl_tRNA_N PF02403.17 EIE79647.1 - 0.0027 17.7 4.2 0.0048 16.8 2.0 2.1 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain AAA_30 PF13604.1 EIE79647.1 - 0.0053 16.3 0.0 0.057 12.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain TIM-br_sig_trns PF09370.5 EIE79647.1 - 0.029 13.4 0.0 0.061 12.3 0.0 1.5 1 0 0 1 1 1 0 TIM-barrel signal transduction protein DUF4463 PF14703.1 EIE79647.1 - 0.078 13.5 0.0 0.27 11.7 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4463) Gemini_C4 PF01492.12 EIE79647.1 - 0.59 9.8 5.6 4.9 6.9 0.4 2.7 2 0 0 2 2 2 0 Geminivirus C4 protein Mnd1 PF03962.10 EIE79647.1 - 1.3 8.7 10.3 21 4.7 3.0 3.4 3 0 0 3 3 3 0 Mnd1 family LSM PF01423.17 EIE79648.1 - 1.5e-10 40.4 0.2 1.9e-10 40.1 0.1 1.1 1 0 0 1 1 1 1 LSM domain Methyltransf_16 PF10294.4 EIE79649.1 - 7.2e-22 77.6 0.0 1.3e-21 76.7 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 EIE79649.1 - 2.1e-07 30.3 0.0 3.5e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 EIE79649.1 - 3.1e-07 30.9 0.0 5.6e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EIE79649.1 - 1.2e-06 28.0 0.0 2.2e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 EIE79649.1 - 2.8e-06 27.7 0.1 5.4e-06 26.8 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIE79649.1 - 8.4e-05 22.1 0.0 0.00013 21.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIE79649.1 - 0.00083 19.3 0.0 0.0014 18.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIE79649.1 - 0.0012 19.1 0.0 0.0042 17.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIE79649.1 - 0.0023 17.6 0.0 0.0033 17.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 EIE79649.1 - 0.0026 17.1 0.0 0.0038 16.6 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 TehB PF03848.9 EIE79649.1 - 0.031 13.4 0.0 0.052 12.7 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_11 PF08241.7 EIE79649.1 - 0.032 14.7 0.0 0.068 13.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain NodS PF05401.6 EIE79649.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) Peptidase_M16 PF00675.15 EIE79650.1 - 1.2e-20 73.7 1.0 1.2e-20 73.7 0.7 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EIE79650.1 - 2.1e-15 56.9 0.2 4.1e-15 55.9 0.1 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain GST_C_2 PF13410.1 EIE79650.1 - 0.2 11.5 1.6 5.7 6.9 0.8 2.5 1 1 1 2 2 2 0 Glutathione S-transferase, C-terminal domain CTP_transf_1 PF01148.15 EIE79651.1 - 2e-29 103.0 1.0 2.6e-29 102.6 0.7 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family DUF3319 PF11782.3 EIE79651.1 - 0.0032 17.2 0.0 0.005 16.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3319) Phosphoesterase PF04185.9 EIE79652.1 - 2.4e-26 92.8 4.4 4.6e-25 88.6 3.1 2.1 1 1 0 1 1 1 1 Phosphoesterase family Phosphoesterase PF04185.9 EIE79653.1 - 8.3e-30 104.2 4.1 2.6e-24 86.1 1.8 2.0 2 0 0 2 2 2 2 Phosphoesterase family SPX PF03105.14 EIE79654.1 - 1.2e-25 90.8 0.4 1.2e-25 90.8 0.3 2.0 2 1 0 2 2 2 1 SPX domain zf-C3HC4_4 PF15227.1 EIE79654.1 - 2.8e-08 33.4 8.7 6.9e-08 32.2 6.0 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 EIE79654.1 - 8.9e-08 31.8 9.6 2.1e-07 30.6 6.7 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EIE79654.1 - 7e-07 28.8 8.4 2.1e-06 27.3 5.9 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EIE79654.1 - 8.7e-07 28.5 6.1 1.7e-06 27.6 4.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIE79654.1 - 1.2e-06 28.4 10.7 2.6e-06 27.3 7.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIE79654.1 - 5.3e-06 25.9 7.9 1.1e-05 24.9 5.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EIE79654.1 - 6.4e-05 22.5 4.8 8e-05 22.2 1.5 2.5 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_4 PF14570.1 EIE79654.1 - 0.00094 18.7 4.4 0.00094 18.7 3.1 1.9 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain CpXC PF14353.1 EIE79654.1 - 0.014 15.4 2.1 0.017 15.0 0.4 2.0 2 0 0 2 2 2 0 CpXC protein TerY-C PF15616.1 EIE79654.1 - 0.03 14.2 4.3 0.047 13.6 2.0 2.0 1 1 1 2 2 2 0 TerY-C metal binding domain zf-MIZ PF02891.15 EIE79654.1 - 0.031 13.7 7.3 0.075 12.5 5.1 1.7 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-rbx1 PF12678.2 EIE79654.1 - 0.18 11.9 3.7 0.47 10.5 2.6 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger zf-Apc11 PF12861.2 EIE79654.1 - 0.23 11.3 3.4 0.52 10.1 2.2 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger C1_4 PF07975.7 EIE79654.1 - 0.37 10.8 6.1 0.3 11.1 2.4 2.2 2 0 0 2 2 2 0 TFIIH C1-like domain zf-RING_6 PF14835.1 EIE79654.1 - 0.89 9.3 8.2 11 5.8 0.6 2.5 1 1 1 2 2 2 0 zf-RING of BARD1-type protein IBR PF01485.16 EIE79654.1 - 2.1 8.2 7.3 12 5.8 5.2 2.3 1 1 0 1 1 1 0 IBR domain Ribosomal_S8e PF01201.17 EIE79655.1 - 8e-51 171.6 0.7 9.5e-51 171.3 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e Ribosomal_L5_C PF00673.16 EIE79656.1 - 1.7e-23 82.1 0.0 2.4e-23 81.6 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 EIE79656.1 - 1.8e-19 69.2 0.1 5.7e-19 67.6 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L5 Ebp2 PF05890.7 EIE79658.1 - 0.072 12.3 8.4 0.091 12.0 5.8 1.3 1 1 0 1 1 1 0 Eukaryotic rRNA processing protein EBP2 XhlA PF10779.4 EIE79658.1 - 0.087 12.7 4.7 0.096 12.6 3.0 1.3 1 1 0 1 1 1 0 Haemolysin XhlA DUF349 PF03993.7 EIE79658.1 - 0.17 12.0 5.8 0.22 11.7 4.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) Prefoldin_2 PF01920.15 EIE79658.1 - 0.78 9.5 7.0 1 9.1 4.9 1.3 1 1 0 1 1 1 0 Prefoldin subunit DUF3740 PF12548.3 EIE79658.1 - 1.6 9.0 6.9 1.6 8.9 4.8 1.1 1 0 0 1 1 1 0 Sulfatase protein DUF1706 PF08020.6 EIE79659.1 - 0.19 11.1 0.8 0.18 11.2 0.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1706) tRNA_m1G_MT PF01746.16 EIE79660.1 - 2e-35 122.1 0.7 2.9e-35 121.5 0.5 1.3 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase zf-C2H2 PF00096.21 EIE79661.1 - 1.2e-08 34.7 11.8 0.0014 18.8 0.1 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIE79661.1 - 4.1e-08 33.1 8.9 1e-07 31.8 0.1 3.9 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EIE79661.1 - 0.00019 21.5 13.5 0.0059 16.8 0.1 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EIE79661.1 - 0.13 12.2 3.4 0.87 9.5 0.1 2.8 3 1 0 3 3 3 0 C2H2-type zinc finger zf-Di19 PF05605.7 EIE79661.1 - 0.43 10.7 3.3 17 5.6 0.0 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Pkinase PF00069.20 EIE79662.1 - 5.9e-67 225.5 0.0 7.5e-67 225.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE79662.1 - 1.2e-33 116.2 0.0 1.5e-33 116.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE79662.1 - 9.6e-06 24.7 0.0 1.6e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 EIE79662.1 - 0.08 12.2 0.0 0.43 9.8 0.0 1.9 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL GTP_EFTU PF00009.22 EIE79663.1 - 3.6e-40 137.3 0.0 5.5e-40 136.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EIE79663.1 - 1.3e-25 89.3 0.0 3.4e-25 87.9 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 EIE79663.1 - 4.9e-22 77.6 0.0 2.3e-21 75.4 0.0 2.2 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EIE79663.1 - 5.7e-10 39.1 0.2 1.2e-09 38.1 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EIE79663.1 - 5.7e-07 29.3 0.0 1.5e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 EIE79663.1 - 4.9e-05 23.2 0.3 0.00012 22.0 0.1 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EIE79663.1 - 0.00011 22.6 0.1 0.00027 21.4 0.1 1.7 1 0 0 1 1 1 1 Miro-like protein Dynamin_N PF00350.18 EIE79663.1 - 0.14 11.9 0.1 2.2 8.0 0.0 2.3 1 1 1 2 2 2 0 Dynamin family HLH PF00010.21 EIE79664.1 - 4.5e-14 51.8 1.9 1.3e-13 50.3 1.3 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SR-25 PF10500.4 EIE79664.1 - 0.052 13.0 5.2 0.058 12.8 3.6 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF2433 PF10360.4 EIE79664.1 - 0.055 13.7 1.8 0.25 11.6 0.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2433) LOH1CR12 PF10158.4 EIE79664.1 - 0.061 13.1 2.7 0.065 13.0 0.8 1.9 2 1 0 2 2 2 0 Tumour suppressor protein Myc-LZ PF02344.10 EIE79664.1 - 0.35 10.5 4.3 8.8 6.0 0.5 2.4 2 0 0 2 2 2 0 Myc leucine zipper domain Ada3 PF10198.4 EIE79665.1 - 1.3e-33 115.5 6.2 2.5e-33 114.6 4.3 1.5 1 0 0 1 1 1 1 Histone acetyltransferases subunit 3 Myc_N PF01056.13 EIE79665.1 - 0.03 13.4 4.4 0.05 12.7 3.0 1.4 1 0 0 1 1 1 0 Myc amino-terminal region Sulfate_transp PF00916.15 EIE79666.1 - 1.8e-40 138.7 6.7 1.8e-40 138.7 4.6 2.0 1 1 0 1 1 1 1 Sulfate transporter family cNMP_binding PF00027.24 EIE79666.1 - 1.8e-13 50.0 0.0 3.6e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.16 EIE79666.1 - 1.3e-10 40.6 0.0 3.1e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 STAS domain SpoIIAA-like PF11964.3 EIE79666.1 - 0.0027 17.9 0.6 0.0071 16.6 0.4 1.7 1 0 0 1 1 1 1 SpoIIAA-like Ammonium_transp PF00909.16 EIE79668.1 - 1.8e-111 372.4 29.4 1.8e-111 372.4 20.4 1.3 2 0 0 2 2 2 1 Ammonium Transporter Family PIP5K PF01504.13 EIE79669.1 - 9.9e-84 280.3 2.0 1.9e-83 279.4 1.4 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase IL10 PF00726.12 EIE79671.1 - 0.19 11.0 0.7 8.3 5.6 0.1 2.3 1 1 1 2 2 2 0 Interleukin 10 Sec2p PF06428.6 EIE79672.1 - 2e-14 53.2 23.3 2e-14 53.2 16.1 2.7 1 1 1 2 2 2 1 GDP/GTP exchange factor Sec2p MAD PF05557.8 EIE79672.1 - 0.051 11.6 43.0 0.075 11.1 29.8 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein Peptidase_S64 PF08192.6 EIE79672.1 - 0.16 10.2 13.3 0.27 9.5 9.2 1.3 1 0 0 1 1 1 0 Peptidase family S64 DegS PF05384.6 EIE79672.1 - 0.22 10.6 27.4 0.083 12.0 16.2 2.3 1 1 1 2 2 2 0 Sensor protein DegS ADIP PF11559.3 EIE79672.1 - 1 9.2 37.9 0.19 11.6 13.4 2.5 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF1664 PF07889.7 EIE79672.1 - 5 6.9 22.3 3.8 7.3 6.7 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Rootletin PF15035.1 EIE79672.1 - 5.4 6.9 38.6 0.34 10.8 7.3 2.9 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Peptidase_C6 PF00851.13 EIE79672.1 - 9.4 4.7 17.2 15 4.0 11.9 1.3 1 0 0 1 1 1 0 Helper component proteinase Ribosomal_S19 PF00203.16 EIE79675.1 - 1.5e-34 117.4 0.2 1.9e-34 117.0 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 Ashwin PF15323.1 EIE79676.1 - 3 7.7 15.1 5.6 6.9 10.4 1.4 1 0 0 1 1 1 0 Developmental protein Lipase_3 PF01764.20 EIE79677.1 - 2e-08 33.9 0.0 2.3e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EIE79677.1 - 0.002 17.8 0.0 0.0022 17.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIE79677.1 - 0.014 15.3 0.0 0.015 15.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.8 EIE79677.1 - 0.053 13.1 0.0 0.07 12.7 0.0 1.1 1 0 0 1 1 1 0 PGAP1-like protein UPF0227 PF05728.7 EIE79677.1 - 0.11 12.2 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) SPRY PF00622.23 EIE79678.1 - 1.4e-15 57.4 0.1 2.8e-15 56.4 0.1 1.5 1 0 0 1 1 1 1 SPRY domain Candida_ALS_N PF11766.3 EIE79678.1 - 0.064 12.1 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Cell-wall agglutinin N-terminal ligand-sugar binding SH3_2 PF07653.12 EIE79678.1 - 0.077 12.4 0.1 0.3 10.5 0.0 2.0 2 0 0 2 2 2 0 Variant SH3 domain CABIT PF12736.2 EIE79678.1 - 0.16 10.9 0.0 0.25 10.3 0.0 1.3 1 0 0 1 1 1 0 Cell-cycle sustaining, positive selection, DUF2015 PF09435.5 EIE79679.1 - 3.7e-27 94.6 0.2 4.4e-27 94.4 0.1 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) PEX11 PF05648.9 EIE79680.1 - 9.1e-55 185.3 2.6 1e-54 185.1 1.8 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) MMS19_C PF12460.3 EIE79680.1 - 0.0067 15.2 0.3 0.0091 14.7 0.2 1.1 1 0 0 1 1 1 1 RNAPII transcription regulator C-terminal RVT_1 PF00078.22 EIE79681.1 - 3.9e-15 55.7 0.0 1.8e-14 53.6 0.0 1.9 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Spectrin PF00435.16 EIE79682.1 - 0.02 15.1 0.4 0.081 13.2 0.0 2.0 2 0 0 2 2 2 0 Spectrin repeat DUF2968 PF11180.3 EIE79682.1 - 0.036 13.4 0.9 0.05 12.9 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) DRMBL PF07522.9 EIE79683.1 - 3.2e-30 104.3 0.0 6.8e-30 103.3 0.0 1.6 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 EIE79683.1 - 3.5e-08 33.2 0.0 1.5e-07 31.1 0.0 2.0 1 1 1 2 2 2 1 Beta-lactamase superfamily domain RMMBL PF07521.7 EIE79683.1 - 0.049 13.4 0.0 0.15 11.8 0.0 1.8 1 0 0 1 1 1 0 RNA-metabolising metallo-beta-lactamase HLH PF00010.21 EIE79684.1 - 6.1e-06 25.8 1.2 3.5e-05 23.3 0.8 2.1 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Phosphonate-bd PF12974.2 EIE79685.1 - 0.0011 18.3 0.0 0.0014 18.0 0.0 1.1 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein Ribosomal_S9 PF00380.14 EIE79686.1 - 2.7e-35 121.2 0.2 3.1e-35 121.0 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 UQ_con PF00179.21 EIE79687.1 - 1.6e-52 176.6 0.0 2e-52 176.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EIE79687.1 - 3.5e-05 23.5 0.0 4.3e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EIE79687.1 - 0.00048 20.0 0.0 0.00055 19.8 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 EIE79687.1 - 0.027 14.1 0.0 0.04 13.6 0.0 1.3 1 0 0 1 1 1 0 UEV domain Arylesterase PF01731.15 EIE79688.1 - 1.8e-05 24.6 0.1 5e-05 23.2 0.1 1.7 1 0 0 1 1 1 1 Arylesterase Str_synth PF03088.11 EIE79688.1 - 0.035 14.1 0.0 0.37 10.8 0.0 2.3 2 0 0 2 2 2 0 Strictosidine synthase Glucan_synthase PF02364.10 EIE79689.1 - 0 1102.1 3.1 0 1101.0 2.2 1.5 1 1 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 EIE79689.1 - 3.2e-35 120.5 1.3 5e-35 119.9 0.1 2.0 2 0 0 2 2 2 1 1,3-beta-glucan synthase subunit FKS1, domain-1 NTP_transferase PF00483.18 EIE79690.1 - 4e-51 173.7 0.0 5.6e-51 173.2 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 EIE79690.1 - 3.7e-11 42.0 7.6 1.2e-08 34.0 3.3 3.4 1 1 2 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EIE79690.1 - 3.8e-10 40.0 0.0 5.5e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 EIE79690.1 - 0.0004 19.8 5.7 0.0004 19.8 3.9 2.7 2 1 1 3 3 3 1 Hexapeptide repeat of succinyl-transferase DUF2810 PF10928.3 EIE79690.1 - 0.0073 16.0 0.1 0.033 13.9 0.0 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF2810) DUF2080 PF09853.4 EIE79690.1 - 0.023 14.4 0.1 0.93 9.2 0.0 3.0 4 0 0 4 4 4 0 Putative transposon-encoded protein (DUF2080) SF3a60_bindingd PF12108.3 EIE79690.1 - 0.061 12.8 0.2 0.13 11.7 0.1 1.6 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain CTP_transf_3 PF02348.14 EIE79690.1 - 0.065 12.8 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 Cytidylyltransferase SRP54 PF00448.17 EIE79690.1 - 0.077 12.4 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Pkinase PF00069.20 EIE79691.1 - 5.6e-70 235.4 0.1 7.1e-70 235.1 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE79691.1 - 1.1e-45 155.7 0.0 1.4e-45 155.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE79691.1 - 3.7e-09 35.9 0.0 2e-08 33.5 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EIE79691.1 - 0.00078 18.5 0.0 0.0014 17.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EIE79691.1 - 0.0054 16.1 0.2 0.26 10.6 0.0 2.3 1 1 0 2 2 2 1 RIO1 family YrbL-PhoP_reg PF10707.4 EIE79691.1 - 0.03 13.6 0.3 0.09 12.1 0.2 1.8 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL 3HCDH_N PF02737.13 EIE79692.1 - 1.9e-53 180.8 3.4 2.5e-53 180.4 2.3 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 EIE79692.1 - 9.2e-35 118.9 0.1 3e-34 117.2 0.0 1.9 3 0 0 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Glyco_hydro_4 PF02056.11 EIE79692.1 - 0.044 13.1 0.1 0.15 11.3 0.1 1.8 1 1 0 1 1 1 0 Family 4 glycosyl hydrolase Ten1 PF12658.2 EIE79694.1 - 0.098 12.4 0.1 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Telomere capping, CST complex subunit Methyltransf_11 PF08241.7 EIE79696.1 - 1.2e-06 28.8 0.6 5.9e-05 23.4 0.0 2.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIE79696.1 - 1.5e-05 24.7 0.0 0.0004 20.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIE79696.1 - 0.00054 19.1 0.1 0.029 13.5 0.0 2.3 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EIE79696.1 - 0.00075 19.8 0.4 3.9 7.8 0.2 3.7 2 2 1 3 3 3 2 Methyltransferase domain Methyltransf_31 PF13847.1 EIE79696.1 - 0.0011 18.6 1.2 0.32 10.5 0.3 3.1 1 1 2 3 3 3 1 Methyltransferase domain Methyltransf_8 PF05148.10 EIE79696.1 - 0.017 14.7 0.1 0.19 11.2 0.0 2.1 1 1 1 2 2 2 0 Hypothetical methyltransferase CMAS PF02353.15 EIE79696.1 - 0.043 12.8 0.2 0.18 10.8 0.0 2.0 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 EIE79696.1 - 0.14 12.6 0.3 1.5 9.3 0.2 2.8 1 1 0 1 1 1 0 Methyltransferase domain CotH PF08757.6 EIE79697.1 - 2.1e-43 148.8 1.0 2.8e-43 148.4 0.7 1.1 1 0 0 1 1 1 1 CotH protein Adaptin_N PF01602.15 EIE79698.1 - 1.8e-103 346.6 3.3 2.2e-103 346.3 2.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 EIE79698.1 - 2.7e-57 192.8 4.1 5.1e-57 191.9 2.8 1.5 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 EIE79698.1 - 9.5e-16 57.8 2.4 0.0015 18.7 0.0 5.0 2 1 3 5 5 5 3 HEAT repeats HEAT_EZ PF13513.1 EIE79698.1 - 0.00085 19.7 0.9 0.24 11.9 0.1 4.1 3 0 0 3 3 3 1 HEAT-like repeat HEAT PF02985.17 EIE79698.1 - 0.0025 17.7 8.0 6.9 7.0 0.1 6.0 6 0 0 6 6 6 2 HEAT repeat Rad60-SLD_2 PF13881.1 EIE79698.1 - 0.059 13.2 0.1 0.31 10.9 0.0 2.2 3 0 0 3 3 3 0 Ubiquitin-2 like Rad60 SUMO-like GRIP PF01465.15 EIE79698.1 - 0.087 12.3 0.2 0.29 10.6 0.1 1.9 1 0 0 1 1 1 0 GRIP domain HEAT_PBS PF03130.11 EIE79698.1 - 0.15 12.6 1.9 23 5.8 0.0 4.0 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat EF-hand_4 PF12763.2 EIE79699.1 - 4.3e-18 64.9 0.0 1.4e-10 40.8 0.0 2.8 3 0 0 3 3 3 2 Cytoskeletal-regulatory complex EF hand TPR_MLP1_2 PF07926.7 EIE79699.1 - 5e-09 35.9 8.7 7.2e-09 35.4 4.8 2.2 1 1 0 1 1 1 1 TPR/MLP1/MLP2-like protein EF-hand_7 PF13499.1 EIE79699.1 - 1.7e-06 28.0 0.0 0.0021 18.1 0.0 3.1 3 0 0 3 3 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EIE79699.1 - 3.4e-06 25.9 0.0 0.00042 19.4 0.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 EIE79699.1 - 0.00021 20.8 0.0 0.82 9.3 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EIE79699.1 - 0.0086 15.8 0.0 0.87 9.6 0.0 2.9 2 0 0 2 2 2 1 EF-hand domain EzrA PF06160.7 EIE79699.1 - 0.014 13.5 17.8 0.023 12.8 12.4 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA EF-hand_5 PF13202.1 EIE79699.1 - 0.054 12.8 0.0 0.23 10.8 0.0 2.1 2 0 0 2 2 2 0 EF hand Laminin_I PF06008.9 EIE79699.1 - 0.083 12.1 19.8 0.014 14.7 9.9 2.3 3 0 0 3 3 3 0 Laminin Domain I CENP-F_leu_zip PF10473.4 EIE79699.1 - 0.17 11.7 29.6 0.18 11.6 17.5 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Mnd1 PF03962.10 EIE79699.1 - 0.27 10.8 20.3 0.54 9.8 14.1 1.5 1 0 0 1 1 1 0 Mnd1 family ADIP PF11559.3 EIE79699.1 - 0.33 10.8 28.9 0.032 14.1 15.3 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding MafB19-deam PF14437.1 EIE79699.1 - 0.33 10.5 4.6 1.1 8.9 0.0 3.0 3 0 0 3 3 2 0 MafB19-like deaminase AAA_13 PF13166.1 EIE79699.1 - 0.49 8.7 18.0 0.012 14.1 7.9 1.6 2 0 0 2 2 2 0 AAA domain DUF3584 PF12128.3 EIE79699.1 - 0.51 7.6 22.0 0.73 7.0 15.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) P4Ha_N PF08336.6 EIE79699.1 - 0.77 9.5 18.6 0.58 9.9 6.8 3.1 2 1 1 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region V_ATPase_I PF01496.14 EIE79699.1 - 2.1 6.1 13.8 3.2 5.4 9.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF342 PF03961.8 EIE79699.1 - 2.9 6.2 23.1 4.6 5.5 15.5 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF342) DUF2009 PF09418.5 EIE79699.1 - 3.4 6.3 8.3 5.3 5.6 5.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2009) APG6 PF04111.7 EIE79699.1 - 3.5 6.5 25.2 7.8 5.4 17.4 1.6 1 0 0 1 1 1 0 Autophagy protein Apg6 Filament PF00038.16 EIE79699.1 - 7.8 5.8 27.6 3.2 7.1 17.3 1.7 2 0 0 2 2 2 0 Intermediate filament protein Usp PF00582.21 EIE79700.1 - 4.1e-23 82.1 0.0 5.1e-23 81.8 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family Nup88 PF10168.4 EIE79701.1 - 1e-27 96.3 7.8 2e-14 52.4 4.9 2.2 2 0 0 2 2 2 2 Nuclear pore component Nup54 PF13874.1 EIE79701.1 - 0.011 15.3 3.2 0.011 15.3 2.2 2.7 3 0 0 3 3 3 0 Nucleoporin complex subunit 54 Bacillus_HBL PF05791.6 EIE79701.1 - 0.11 11.8 11.8 0.035 13.4 3.4 2.5 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Pox_A_type_inc PF04508.7 EIE79701.1 - 0.55 10.1 3.9 0.31 10.9 0.5 2.5 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Mito_carr PF00153.22 EIE79702.1 - 1.5e-56 188.0 4.9 5.8e-24 83.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF336 PF03928.9 EIE79703.1 - 3.5e-05 23.6 0.0 3.9e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF336) Na_Ca_ex PF01699.19 EIE79704.1 - 5.1e-41 139.5 35.4 2.6e-22 78.9 7.9 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein TFX_C PF14601.1 EIE79705.1 - 0.015 15.1 0.1 0.026 14.3 0.1 1.4 1 0 0 1 1 1 0 DNA_binding protein, TFX, C-term Hexokinase_1 PF00349.16 EIE79705.1 - 0.052 12.8 0.1 0.088 12.1 0.1 1.3 1 0 0 1 1 1 0 Hexokinase I-set PF07679.11 EIE79706.1 - 0.0015 18.3 0.1 10 6.0 0.0 4.5 4 0 0 4 4 4 3 Immunoglobulin I-set domain DUF1769 PF08588.5 EIE79708.1 - 0.078 12.9 1.0 0.13 12.1 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1769) DNA_pol3_a_NII PF11490.3 EIE79709.1 - 0.6 9.7 8.5 1.6 8.3 3.9 2.1 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus II VIT1 PF01988.14 EIE79710.1 - 4.1e-73 245.3 0.3 4.8e-73 245.1 0.2 1.0 1 0 0 1 1 1 1 VIT family Pectate_lyase_2 PF06917.7 EIE79711.1 - 0.015 13.5 0.1 0.019 13.2 0.1 1.1 1 0 0 1 1 1 0 Periplasmic pectate lyase Hemocyanin_N PF03722.9 EIE79711.1 - 0.14 12.2 1.7 0.7 10.0 0.2 2.6 2 1 1 3 3 3 0 Hemocyanin, all-alpha domain UCH_1 PF13423.1 EIE79712.1 - 5.5e-31 108.0 0.0 8.3e-31 107.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.24 EIE79712.1 - 4.5e-18 65.3 0.2 1.1e-17 64.0 0.2 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase HEAT PF02985.17 EIE79713.1 - 3.7e-07 29.6 9.8 0.64 10.2 0.0 6.7 6 1 1 7 7 7 3 HEAT repeat HEAT_2 PF13646.1 EIE79713.1 - 5.8e-07 29.7 0.0 0.0021 18.3 0.0 3.6 3 1 0 3 3 3 2 HEAT repeats Cohesin_HEAT PF12765.2 EIE79713.1 - 4.5e-06 26.5 0.3 1.5 8.8 0.1 5.7 6 0 0 6 6 6 2 HEAT repeat associated with sister chromatid cohesion Proteasom_PSMB PF10508.4 EIE79713.1 - 5.7e-05 21.5 0.1 0.022 13.0 0.0 3.2 2 1 0 3 3 3 2 Proteasome non-ATPase 26S subunit Fork_head PF00250.13 EIE79714.1 - 3.1e-33 113.6 0.1 5.3e-33 112.9 0.0 1.4 1 0 0 1 1 1 1 Fork head domain 2OG-FeII_Oxy_3 PF13640.1 EIE79715.1 - 1.6e-11 44.5 0.1 2.7e-11 43.8 0.1 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EIE79715.1 - 1.3e-08 34.3 0.0 2.7e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pox_C4_C10 PF03336.8 EIE79715.1 - 0.00012 20.9 0.0 0.00014 20.7 0.0 1.1 1 0 0 1 1 1 1 Poxvirus C4/C10 protein 2OG-FeII_Oxy PF03171.15 EIE79715.1 - 0.0007 19.8 0.1 0.0012 19.1 0.1 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Lon_C PF05362.8 EIE79716.1 - 3.2e-74 248.6 1.2 3.9e-74 248.3 0.3 1.6 2 0 0 2 2 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 EIE79716.1 - 2.3e-26 92.7 2.6 2.3e-26 92.7 0.5 2.0 1 1 1 2 2 2 1 ATP-dependent protease La (LON) domain AAA PF00004.24 EIE79716.1 - 2.8e-23 82.5 0.0 7.7e-23 81.1 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.1 EIE79716.1 - 1.3e-06 27.9 0.0 7.7e-06 25.4 0.0 2.2 1 1 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_17 PF13207.1 EIE79716.1 - 1.1e-05 26.2 0.0 5.5e-05 23.9 0.0 2.3 2 0 0 2 2 1 1 AAA domain AAA_5 PF07728.9 EIE79716.1 - 1.1e-05 25.1 0.0 3.2e-05 23.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_PrkA PF08298.6 EIE79716.1 - 3.5e-05 22.6 0.0 6.5e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 PrkA AAA domain AAA_16 PF13191.1 EIE79716.1 - 5.9e-05 23.1 0.1 0.00017 21.6 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 EIE79716.1 - 0.0001 21.4 0.0 0.00053 19.1 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EIE79716.1 - 0.00028 20.7 0.0 0.0018 18.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.6 EIE79716.1 - 0.0004 20.0 0.0 0.00083 18.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EIE79716.1 - 0.00074 19.6 0.0 0.019 15.1 0.0 2.6 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EIE79716.1 - 0.0027 16.8 0.0 0.0049 16.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_2 PF07724.9 EIE79716.1 - 0.008 16.1 0.0 0.048 13.5 0.0 2.2 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 EIE79716.1 - 0.0083 16.4 0.0 0.0083 16.4 0.0 2.6 4 0 0 4 4 1 1 AAA domain IstB_IS21 PF01695.12 EIE79716.1 - 0.015 14.6 0.0 0.034 13.5 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.17 EIE79716.1 - 0.016 15.3 0.0 0.065 13.4 0.0 2.1 1 0 0 1 1 1 0 RNA helicase SKI PF01202.17 EIE79716.1 - 0.018 14.9 0.8 0.21 11.4 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase AAA_33 PF13671.1 EIE79716.1 - 0.022 14.6 0.0 0.048 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 EIE79716.1 - 0.046 13.4 0.0 0.13 11.9 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.1 EIE79716.1 - 0.065 12.7 0.2 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EIE79716.1 - 0.29 11.4 0.0 0.29 11.4 0.0 2.9 1 1 1 2 2 1 0 AAA domain DUF3741 PF12552.3 EIE79717.1 - 0.047 13.4 2.2 0.052 13.2 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3741) DUF3685 PF12452.3 EIE79717.1 - 0.065 12.3 0.6 0.11 11.6 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3685) DUF1323 PF07037.6 EIE79717.1 - 0.1 12.7 0.1 0.11 12.6 0.1 1.2 1 1 0 1 1 1 0 Putative transcription regulator (DUF1323) DUF543 PF04418.7 EIE79718.1 - 0.0045 16.9 0.3 0.0046 16.8 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Fungal_trans PF04082.13 EIE79719.1 - 0.0089 14.9 0.3 0.0089 14.9 0.2 2.1 2 1 1 3 3 3 1 Fungal specific transcription factor domain YlqD PF11068.3 EIE79719.1 - 0.022 14.8 0.3 0.045 13.8 0.2 1.4 1 0 0 1 1 1 0 YlqD protein DUF2408 PF10303.4 EIE79719.1 - 0.026 14.6 0.0 0.26 11.4 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2408) Snapin_Pallidin PF14712.1 EIE79719.1 - 7.6 6.9 8.0 6.5 7.1 0.1 2.7 2 0 0 2 2 2 0 Snapin/Pallidin Ank_5 PF13857.1 EIE79720.1 - 2.3e-10 40.3 3.3 5.2e-07 29.6 0.1 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EIE79720.1 - 4.6e-10 39.6 0.8 1.2e-09 38.3 0.5 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EIE79720.1 - 1e-09 38.6 0.7 1.3e-07 31.9 0.4 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 EIE79720.1 - 2e-09 36.7 7.0 6.3e-06 25.7 0.1 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 EIE79720.1 - 9.4e-08 31.5 5.0 0.00082 19.3 0.1 3.3 3 0 0 3 3 3 2 Ankyrin repeat TIG PF01833.19 EIE79720.1 - 2.6e-07 30.5 0.0 1.5e-06 28.1 0.0 2.4 2 0 0 2 2 2 1 IPT/TIG domain Aconitase PF00330.15 EIE79720.1 - 0.087 11.2 0.1 0.13 10.6 0.1 1.2 1 0 0 1 1 1 0 Aconitase family (aconitate hydratase) Linker_histone PF00538.14 EIE79722.1 - 0.077 13.0 0.3 0.35 10.9 0.0 2.3 2 0 0 2 2 2 0 linker histone H1 and H5 family Transposase_mut PF00872.13 EIE79723.1 - 0.00022 19.9 2.2 0.00036 19.1 1.5 1.3 1 0 0 1 1 1 1 Transposase, Mutator family SWIM PF04434.12 EIE79723.1 - 0.00023 20.5 1.6 0.00055 19.3 1.1 1.7 1 0 0 1 1 1 1 SWIM zinc finger Lipocalin PF00061.18 EIE79723.1 - 0.034 14.1 0.0 0.082 12.8 0.0 1.6 1 0 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family SF3a60_bindingd PF12108.3 EIE79723.1 - 0.067 12.7 0.0 0.23 11.0 0.0 2.0 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain Cyclin PF08613.6 EIE79727.1 - 2.1e-13 50.9 0.3 4.5e-13 49.8 0.1 1.6 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 EIE79727.1 - 0.00037 20.0 0.0 0.00072 19.1 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain NKWYS PF10364.4 EIE79727.1 - 0.016 14.9 0.3 0.023 14.4 0.2 1.3 1 0 0 1 1 1 0 Putative capsular polysaccharide synthesis protein DUF3544 PF12064.3 EIE79727.1 - 0.083 12.6 0.2 0.12 12.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3544) Dak1 PF02733.12 EIE79729.1 - 1.6e-49 168.2 0.1 2.1e-49 167.8 0.1 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 EIE79729.1 - 6.7e-38 130.0 0.1 1e-37 129.5 0.1 1.3 1 0 0 1 1 1 1 DAK2 domain TMCO5 PF14992.1 EIE79731.1 - 0.002 17.3 10.8 0.0034 16.5 7.5 1.4 1 0 0 1 1 1 1 TMCO5 family CENP-Q PF13094.1 EIE79731.1 - 0.011 15.7 15.9 0.023 14.7 11.0 1.5 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF1803 PF08820.5 EIE79731.1 - 0.036 13.7 2.7 0.13 11.9 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1803) DUF4279 PF14106.1 EIE79731.1 - 0.091 12.6 2.4 0.33 10.8 1.7 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4279) CHD5 PF04420.9 EIE79731.1 - 0.12 12.0 6.4 0.24 11.0 4.4 1.5 1 0 0 1 1 1 0 CHD5-like protein EMP24_GP25L PF01105.19 EIE79731.1 - 0.16 11.6 3.1 2.2 7.9 1.7 2.4 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD IncA PF04156.9 EIE79731.1 - 0.26 10.8 15.7 0.5 9.9 10.9 1.4 1 0 0 1 1 1 0 IncA protein DUF812 PF05667.6 EIE79731.1 - 0.27 9.6 13.0 0.41 9.1 9.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) SPT16 PF08644.6 EIE79731.1 - 0.36 10.6 6.1 0.7 9.7 4.2 1.5 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) Atg14 PF10186.4 EIE79731.1 - 0.38 9.6 10.0 0.72 8.7 6.9 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 V_ATPase_I PF01496.14 EIE79731.1 - 0.58 7.9 6.9 0.79 7.4 4.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Noelin-1 PF12308.3 EIE79731.1 - 0.73 9.6 7.6 2.4 8.0 2.2 2.9 2 2 0 2 2 2 0 Neurogenesis glycoprotein DUF4140 PF13600.1 EIE79731.1 - 3 8.3 12.4 18 5.8 5.6 3.0 2 1 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) HlyD_2 PF12700.2 EIE79731.1 - 4.9 6.2 10.2 8.3 5.4 7.1 1.3 1 0 0 1 1 1 0 HlyD family secretion protein Bap31 PF05529.7 EIE79731.1 - 5.8 6.3 9.3 13 5.2 6.5 1.5 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like HSP70 PF00012.15 EIE79731.1 - 7.8 4.2 9.0 12 3.6 6.3 1.2 1 0 0 1 1 1 0 Hsp70 protein DUF342 PF03961.8 EIE79731.1 - 8.3 4.7 9.0 12 4.1 6.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) eIF3_subunit PF08597.5 EIE79732.1 - 6e-53 179.9 35.2 6.8e-53 179.7 24.4 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit CHCH PF06747.8 EIE79733.1 - 3.3e-08 33.2 2.8 6.6e-08 32.2 1.9 1.5 1 0 0 1 1 1 1 CHCH domain hNIFK_binding PF12196.3 EIE79733.1 - 0.33 10.3 2.6 0.61 9.5 1.8 1.5 1 0 0 1 1 1 0 FHA Ki67 binding domain of hNIFK GCK PF07802.6 EIE79733.1 - 0.41 10.8 5.2 0.1 12.7 1.4 1.7 2 0 0 2 2 2 0 GCK domain Voldacs PF03517.8 EIE79733.1 - 0.85 9.4 5.2 1.6 8.6 3.6 1.5 1 1 0 1 1 1 0 Regulator of volume decrease after cellular swelling SOG2 PF10428.4 EIE79734.1 - 0.31 9.6 8.9 0.36 9.4 6.1 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein SKN1 PF03935.10 EIE79735.1 - 0.0086 14.2 0.0 0.012 13.8 0.0 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) LMBR1 PF04791.11 EIE79735.1 - 0.14 10.7 1.2 0.19 10.2 0.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein p450 PF00067.17 EIE79737.1 - 2e-67 227.6 0.3 2.9e-67 227.1 0.2 1.2 1 0 0 1 1 1 1 Cytochrome P450 Chitin_synth_2 PF03142.10 EIE79738.1 - 8.9e-232 770.1 0.3 1.3e-231 769.5 0.2 1.3 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 EIE79738.1 - 4.9e-90 302.5 0.2 6.1e-90 302.2 0.2 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Glyco_tranf_2_3 PF13641.1 EIE79738.1 - 5.6e-17 62.2 0.0 3.3e-12 46.6 0.0 2.6 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 EIE79738.1 - 3.6e-16 58.7 0.3 3.1e-12 46.1 0.1 2.6 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.6 EIE79738.1 - 3.1e-14 52.4 0.7 7.9e-14 51.1 0.5 1.8 1 0 0 1 1 1 1 DEK C terminal domain Glyco_trans_2_3 PF13632.1 EIE79738.1 - 8.8e-14 51.6 0.8 8.8e-14 51.6 0.5 2.8 4 0 0 4 4 4 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.1 EIE79738.1 - 0.00037 19.8 0.1 0.12 11.6 0.0 3.1 3 0 0 3 3 3 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EIE79738.1 - 0.0017 18.0 0.0 0.036 13.7 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 eIF-5_eIF-2B PF01873.12 EIE79740.1 - 7.8e-45 151.5 0.4 1.6e-44 150.5 0.3 1.5 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 EIE79740.1 - 2.7e-28 97.7 5.1 4.7e-27 93.7 0.5 2.8 2 0 0 2 2 2 2 eIF4-gamma/eIF5/eIF2-epsilon SRF-TF PF00319.13 EIE79740.1 - 0.084 12.1 0.3 0.22 10.7 0.2 1.6 1 0 0 1 1 1 0 SRF-type transcription factor (DNA-binding and dimerisation domain) DDE_3 PF13358.1 EIE79743.1 - 3.9e-18 65.6 0.0 4.1e-18 65.5 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE79743.1 - 0.042 13.9 0.0 0.056 13.5 0.0 1.2 1 0 0 1 1 1 0 Integrase core domain O-FucT PF10250.4 EIE79745.1 - 0.064 12.3 0.0 1.2 8.1 0.0 2.6 1 1 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase Tubulin PF00091.20 EIE79746.1 - 6.3e-73 245.1 0.0 1e-72 244.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EIE79746.1 - 2.2e-48 163.4 0.0 3.9e-48 162.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EIE79746.1 - 9e-06 25.7 0.0 2.1e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Myb_DNA-binding PF00249.26 EIE79749.1 - 2.9e-39 132.8 6.9 8.2e-15 54.6 0.2 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EIE79749.1 - 1.6e-31 108.1 5.8 4.5e-15 55.4 0.1 3.1 2 1 1 3 3 3 3 Myb-like DNA-binding domain Rap1_C PF11626.3 EIE79749.1 - 0.00013 21.8 0.8 0.79 9.6 0.0 3.2 1 1 1 3 3 3 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_4 PF13837.1 EIE79749.1 - 0.00014 21.8 11.1 0.2 11.8 0.8 4.0 3 2 1 4 4 4 2 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 EIE79749.1 - 0.022 14.6 5.4 6.4 6.7 0.4 4.6 4 1 0 4 4 4 0 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.4 EIE79749.1 - 0.25 11.5 5.1 3.3 7.9 0.6 3.1 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Pup PF05639.6 EIE79750.1 - 0.1 13.1 0.9 0.1 13.1 0.7 1.6 2 0 0 2 2 2 0 Pup-like protein Arf PF00025.16 EIE79751.1 - 7e-80 266.3 0.1 7.9e-80 266.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EIE79751.1 - 2.9e-13 49.4 0.0 3.5e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EIE79751.1 - 6.4e-13 48.4 0.0 7.3e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EIE79751.1 - 2.1e-12 46.4 1.7 2.2e-09 36.5 0.2 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EIE79751.1 - 5e-11 42.1 0.0 5.9e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EIE79751.1 - 4.9e-09 36.7 0.0 6.8e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EIE79751.1 - 6.8e-06 26.0 0.0 1e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 EIE79751.1 - 0.0054 15.8 0.3 0.0094 15.0 0.2 1.6 1 1 0 1 1 1 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 EIE79751.1 - 0.043 13.2 0.1 0.38 10.1 0.0 1.9 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 EIE79751.1 - 0.075 12.9 0.1 0.13 12.1 0.1 1.7 1 1 0 1 1 1 0 AAA domain Ribosomal_L30_N PF08079.7 EIE79752.1 - 4.2e-22 77.9 15.7 8.1e-22 77.0 10.9 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 EIE79752.1 - 1.7e-20 72.2 2.3 3.9e-20 71.1 1.1 2.1 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e DUF2782 PF11191.3 EIE79752.1 - 0.072 13.0 1.3 0.13 12.2 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2782) ADIP PF11559.3 EIE79752.1 - 9.1 6.1 11.2 16 5.3 7.8 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Y_phosphatase PF00102.22 EIE79753.1 - 1.3e-66 224.3 0.2 1.3e-66 224.3 0.1 2.0 2 1 0 2 2 2 1 Protein-tyrosine phosphatase DSPc PF00782.15 EIE79753.1 - 4.7e-05 22.9 0.5 0.00011 21.7 0.0 2.0 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 EIE79753.1 - 0.00099 19.1 0.0 0.00099 19.1 0.0 2.7 2 2 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 EIE79753.1 - 0.0012 19.1 3.0 0.0014 18.9 0.0 2.3 2 1 0 2 2 2 1 Tyrosine phosphatase family Pkinase PF00069.20 EIE79754.1 - 1.4e-53 181.7 0.0 3.7e-39 134.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIE79754.1 - 2.8e-21 75.7 0.0 5.2e-21 74.8 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EIE79754.1 - 1.6e-06 27.3 0.1 2.5e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EIE79754.1 - 2.2e-05 23.6 0.0 5.5e-05 22.2 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EIE79754.1 - 0.00059 19.6 0.0 0.0012 18.6 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EIE79754.1 - 0.0041 16.7 0.1 0.0066 16.0 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase HAP1_N PF04849.8 EIE79755.1 - 0.0014 17.6 3.4 0.0018 17.2 2.3 1.1 1 0 0 1 1 1 1 HAP1 N-terminal conserved region DivIC PF04977.10 EIE79755.1 - 0.0016 17.8 5.0 0.0022 17.4 3.0 1.6 1 1 0 1 1 1 1 Septum formation initiator TMF_TATA_bd PF12325.3 EIE79755.1 - 0.0036 17.0 4.6 0.0049 16.5 3.2 1.3 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding DUF3405 PF11885.3 EIE79755.1 - 0.0042 15.4 0.1 0.0043 15.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) DUF3450 PF11932.3 EIE79755.1 - 0.0075 15.5 2.2 0.011 15.0 1.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) Filament PF00038.16 EIE79755.1 - 0.012 15.1 3.8 0.015 14.8 2.6 1.1 1 0 0 1 1 1 0 Intermediate filament protein APG6 PF04111.7 EIE79755.1 - 0.014 14.4 5.2 0.017 14.1 3.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 AAA_13 PF13166.1 EIE79755.1 - 0.014 13.8 2.4 0.017 13.6 1.7 1.0 1 0 0 1 1 1 0 AAA domain DUF2968 PF11180.3 EIE79755.1 - 0.014 14.7 2.0 0.021 14.2 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) BRE1 PF08647.6 EIE79755.1 - 0.022 14.7 3.2 0.04 13.8 2.2 1.4 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase TarH PF02203.10 EIE79755.1 - 0.041 13.7 0.8 0.058 13.2 0.6 1.2 1 0 0 1 1 1 0 Tar ligand binding domain homologue FCH PF00611.18 EIE79755.1 - 0.054 13.6 3.3 0.096 12.8 2.3 1.4 1 0 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain DUF904 PF06005.7 EIE79755.1 - 0.064 13.5 8.1 0.14 12.4 5.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF904) DUF724 PF05266.9 EIE79755.1 - 0.071 12.7 2.8 0.095 12.3 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) TMF_DNA_bd PF12329.3 EIE79755.1 - 0.11 12.3 13.8 0.14 12.0 8.1 2.3 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Nup54 PF13874.1 EIE79755.1 - 0.21 11.2 4.5 0.31 10.7 3.1 1.2 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 ADIP PF11559.3 EIE79755.1 - 0.22 11.4 6.8 0.31 10.9 4.7 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding V_ATPase_I PF01496.14 EIE79755.1 - 0.28 9.0 2.1 0.28 8.9 1.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF972 PF06156.8 EIE79755.1 - 0.84 10.0 5.5 1.4 9.3 3.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF972) bZIP_1 PF00170.16 EIE79755.1 - 1.3 9.0 8.0 3.7 7.5 1.6 2.3 1 1 1 2 2 2 0 bZIP transcription factor NYD-SP28 PF14772.1 EIE79755.1 - 2.1 8.4 7.5 24 5.1 4.8 2.1 1 1 1 2 2 2 0 Sperm tail zf-RVT PF13966.1 EIE79757.1 - 0.034 14.4 0.0 0.038 14.3 0.0 1.1 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase GSHPx PF00255.14 EIE79758.1 - 7.2e-35 118.6 0.0 8.1e-35 118.4 0.0 1.0 1 0 0 1 1 1 1 Glutathione peroxidase Redoxin PF08534.5 EIE79758.1 - 0.00092 18.7 0.0 0.00092 18.7 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EIE79758.1 - 0.0017 17.9 0.0 0.002 17.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family RPA_interact_C PF14768.1 EIE79759.1 - 0.061 13.7 0.0 0.17 12.2 0.0 1.9 1 0 0 1 1 1 0 Replication protein A interacting C-terminal Tbf5 PF06331.7 EIE79760.1 - 3e-13 49.3 0.3 3.3e-13 49.2 0.2 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 DDE_3 PF13358.1 EIE79761.1 - 0.03 14.0 0.0 0.033 13.9 0.0 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease VEFS-Box PF09733.4 EIE79762.1 - 0.0027 17.3 0.0 0.0033 17.0 0.0 1.1 1 0 0 1 1 1 1 VEFS-Box of polycomb protein Abhydrolase_5 PF12695.2 EIE79765.1 - 3.1e-19 69.1 0.0 8.1e-19 67.8 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIE79765.1 - 7e-17 62.0 0.0 8.2e-15 55.2 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIE79765.1 - 2e-05 24.2 0.0 0.0019 17.7 0.0 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EIE79765.1 - 0.0016 17.8 0.0 0.4 10.0 0.0 2.4 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 EIE79765.1 - 0.0096 15.1 0.0 0.063 12.4 0.0 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.13 EIE79765.1 - 0.033 13.4 0.0 0.32 10.2 0.0 2.2 1 1 0 1 1 1 0 Dienelactone hydrolase family AXE1 PF05448.7 EIE79765.1 - 0.04 12.4 0.3 0.78 8.1 0.0 2.8 3 1 1 4 4 4 0 Acetyl xylan esterase (AXE1) FSH1 PF03959.8 EIE79765.1 - 0.047 13.1 0.0 0.076 12.4 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) DUF818 PF05677.7 EIE79765.1 - 0.059 12.0 0.0 0.088 11.5 0.0 1.2 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) BAAT_C PF08840.6 EIE79765.1 - 0.11 12.2 0.0 6.7 6.3 0.0 2.4 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Myb_DNA-bind_6 PF13921.1 EIE79767.1 - 6.9e-42 141.3 14.0 1.2e-18 66.8 0.9 4.8 3 1 2 5 5 5 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EIE79767.1 - 5.6e-41 138.3 15.8 2.9e-14 52.8 0.2 3.8 4 0 0 4 4 4 3 Myb-like DNA-binding domain Rap1_C PF11626.3 EIE79767.1 - 5.7e-08 32.5 1.9 0.07 13.0 0.6 4.2 2 1 0 3 3 3 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain zf-C2H2_4 PF13894.1 EIE79767.1 - 0.0025 18.0 8.3 2.6 8.5 0.1 3.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EIE79767.1 - 0.022 15.0 16.1 0.064 13.6 0.4 3.8 3 0 0 3 3 3 0 Zinc finger, C2H2 type Myb_DNA-bind_5 PF13873.1 EIE79767.1 - 1.6 8.6 8.0 12 5.8 0.2 4.6 4 1 0 4 4 4 0 Myb/SANT-like DNA-binding domain zf-C2H2_6 PF13912.1 EIE79767.1 - 3.5 7.6 6.9 18 5.4 1.0 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger COesterase PF00135.23 EIE79768.1 - 2.4e-25 89.2 0.0 2.7e-25 89.0 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family COesterase PF00135.23 EIE79769.1 - 2.6e-35 122.1 0.1 3e-35 121.9 0.1 1.0 1 0 0 1 1 1 1 Carboxylesterase family WW PF00397.21 EIE79771.1 - 3e-13 49.3 2.5 7.9e-13 48.0 1.8 1.8 1 0 0 1 1 1 1 WW domain DUF2076 PF09849.4 EIE79771.1 - 0.00023 21.3 1.1 0.00027 21.0 0.7 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) DUF1183 PF06682.7 EIE79771.1 - 0.43 10.1 8.2 0.55 9.7 5.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) WWbp PF10349.4 EIE79771.1 - 2 9.3 32.5 0.77 10.6 19.6 2.2 1 1 1 2 2 2 0 WW-domain ligand protein Myosin_head PF00063.16 EIE79772.1 - 5.5e-236 784.8 5.7 1.1e-235 783.9 2.9 1.9 1 1 1 2 2 2 1 Myosin head (motor domain) IQ PF00612.22 EIE79772.1 - 1.5e-08 33.5 33.8 0.00021 20.6 0.7 5.8 6 0 0 6 6 6 4 IQ calmodulin-binding motif DIL PF01843.14 EIE79772.1 - 0.0021 17.9 0.1 0.0091 15.8 0.0 2.2 1 0 0 1 1 1 1 DIL domain QLQ PF08880.6 EIE79772.1 - 0.0075 15.6 0.8 2 7.9 0.2 3.1 2 0 0 2 2 2 1 QLQ CbiA PF01656.18 EIE79772.1 - 0.0083 15.5 0.1 0.021 14.2 0.1 1.7 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.1 EIE79772.1 - 0.014 15.5 0.0 0.071 13.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EIE79772.1 - 0.021 14.5 0.0 0.052 13.2 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain ABC_tran PF00005.22 EIE79772.1 - 0.038 14.2 3.5 0.24 11.7 0.0 3.3 3 0 0 3 3 3 0 ABC transporter AAA_16 PF13191.1 EIE79772.1 - 0.05 13.5 0.0 0.16 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain Sas10 PF09368.5 EIE79773.1 - 3.6e-28 97.5 8.5 3.6e-28 97.5 5.9 2.5 2 0 0 2 2 2 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 EIE79773.1 - 4.3e-12 46.0 2.1 4.3e-12 46.0 1.4 3.2 3 0 0 3 3 3 1 Sas10/Utp3/C1D family Sec20 PF03908.8 EIE79773.1 - 8.2 6.2 9.5 0.47 10.1 0.5 3.0 3 0 0 3 3 3 0 Sec20 Bud13 PF09736.4 EIE79774.1 - 5.1e-43 146.8 7.9 5.1e-43 146.8 5.5 1.9 2 0 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex DUF4407 PF14362.1 EIE79774.1 - 7.9 5.3 8.3 10 4.9 5.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Homeobox PF00046.24 EIE79775.1 - 1.8e-15 56.3 0.6 3e-15 55.5 0.4 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EIE79775.1 - 0.0039 16.8 0.0 0.01 15.5 0.0 1.6 1 0 0 1 1 1 1 Homeobox KN domain HTH_23 PF13384.1 EIE79775.1 - 0.025 14.2 0.1 0.042 13.5 0.1 1.4 1 0 0 1 1 1 0 Homeodomain-like domain Pyrophosphatase PF00719.14 EIE79776.1 - 6.7e-34 116.5 0.2 3.9e-21 75.1 0.0 2.2 1 1 1 2 2 2 2 Inorganic pyrophosphatase Elongin_A PF06881.6 EIE79777.1 - 1.1 9.6 0.0 1.1 9.6 0.0 3.2 2 1 1 3 3 3 0 RNA polymerase II transcription factor SIII (Elongin) subunit A p450 PF00067.17 EIE79778.1 - 2.3e-54 184.6 0.0 2.8e-54 184.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1900 PF08954.6 EIE79779.1 - 0.021 14.3 0.0 0.051 13.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1900) p450 PF00067.17 EIE79780.1 - 1.3e-73 248.1 0.0 7.1e-64 216.0 0.0 2.2 1 1 1 2 2 2 2 Cytochrome P450 G_glu_transpept PF01019.16 EIE79781.1 - 1.4e-137 459.2 0.0 1.7e-137 459.0 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase AAA_23 PF13476.1 EIE79782.1 - 0.18 12.0 1.0 0.21 11.8 0.7 1.0 1 0 0 1 1 1 0 AAA domain Myb_DNA-bind_3 PF12776.2 EIE79782.1 - 0.19 12.3 1.2 0.51 11.0 0.8 1.8 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain GIT_SHD PF08518.6 EIE79783.1 - 3.5e-24 83.8 3.3 9.2e-14 50.5 0.1 2.4 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT DUF3410 PF11890.3 EIE79783.1 - 0.068 12.8 0.4 0.13 11.9 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3410) HalX PF08663.5 EIE79783.1 - 1.6 8.7 8.8 2.9 7.9 0.3 3.2 3 1 1 4 4 4 0 HalX domain DUF4451 PF14616.1 EIE79784.1 - 2.4e-26 91.9 8.7 2.4e-26 91.9 6.0 2.9 3 1 0 3 3 3 1 Domain of unknown function (DUF4451) Fungal_trans PF04082.13 EIE79786.1 - 0.00039 19.3 0.6 0.0013 17.7 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Tom7 PF08038.7 EIE79787.1 - 0.021 14.2 0.0 0.034 13.5 0.0 1.4 1 0 0 1 1 1 0 TOM7 family Ribosomal_L23eN PF03939.8 EIE79789.1 - 1.8e-20 72.6 13.1 3.8e-20 71.6 9.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.15 EIE79789.1 - 2.1e-19 69.2 2.5 2.1e-19 69.2 1.8 1.9 2 0 0 2 2 2 1 Ribosomal protein L23 RabGAP-TBC PF00566.13 EIE79790.1 - 2.2e-54 184.1 1.2 6.8e-54 182.5 0.5 2.1 1 1 1 2 2 2 1 Rab-GTPase-TBC domain IncA PF04156.9 EIE79790.1 - 0.09 12.3 12.2 0.096 12.2 7.5 1.8 1 1 0 1 1 1 0 IncA protein HALZ PF02183.13 EIE79790.1 - 0.66 9.7 10.1 0.47 10.2 1.3 3.6 4 0 0 4 4 4 0 Homeobox associated leucine zipper DivIC PF04977.10 EIE79790.1 - 0.83 9.1 5.5 2.2 7.8 0.0 2.9 1 1 1 2 2 2 0 Septum formation initiator APG6 PF04111.7 EIE79790.1 - 3.5 6.5 12.2 6.6 5.6 8.5 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 Rho_Binding PF08912.6 EIE79790.1 - 4.5 7.6 10.6 0.32 11.3 1.8 3.2 3 1 1 4 4 4 0 Rho Binding DUF972 PF06156.8 EIE79790.1 - 4.6 7.6 8.3 7 7.0 2.7 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF972) RVT_1 PF00078.22 EIE79791.1 - 5.5e-27 94.5 0.0 1.2e-26 93.4 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EIE79791.1 - 1e-17 63.8 2.8 2.4e-17 62.6 1.5 2.0 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EIE79791.1 - 1e-07 32.1 0.1 2.4e-07 30.9 0.1 1.7 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DivIVA PF05103.8 EIE79792.1 - 0.0029 17.6 1.2 0.0029 17.6 0.8 1.5 2 0 0 2 2 2 1 DivIVA protein RVT_2 PF07727.9 EIE79792.1 - 0.038 12.9 0.0 0.055 12.4 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Mto2_bdg PF12808.2 EIE79792.1 - 0.15 12.1 15.6 0.073 13.1 1.0 3.4 4 0 0 4 4 4 0 Micro-tubular organiser Mto1 C-term Mto2-binding region SlyX PF04102.7 EIE79792.1 - 0.18 12.2 13.0 0.072 13.4 2.0 2.9 3 0 0 3 3 3 0 SlyX DUF3450 PF11932.3 EIE79792.1 - 3.8 6.6 16.1 29 3.8 11.2 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) DUF4140 PF13600.1 EIE79792.1 - 5.2 7.5 9.4 4.9 7.6 0.3 2.6 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Spc24 PF08286.6 EIE79792.1 - 5.9 6.6 8.0 0.99 9.1 1.9 2.3 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Fib_alpha PF08702.5 EIE79792.1 - 7.4 6.6 10.6 3.7 7.6 1.9 2.3 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Condensin2nSMC PF12422.3 EIE79794.1 - 0.12 12.0 0.2 0.17 11.6 0.1 1.4 1 1 0 1 1 1 0 Condensin II non structural maintenance of chromosomes subunit DDE_3 PF13358.1 EIE79795.1 - 5.9e-26 90.9 0.0 1.2e-25 89.9 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 EIE79795.1 - 2.4e-09 37.3 0.0 1.3e-08 34.9 0.0 2.2 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.1 EIE79795.1 - 4.1e-05 24.2 0.1 0.00021 22.0 0.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.1 EIE79795.1 - 0.00015 21.6 0.0 0.00051 19.9 0.0 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain rve PF00665.21 EIE79795.1 - 0.001 19.1 0.0 0.0029 17.7 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain HTH_23 PF13384.1 EIE79795.1 - 0.018 14.6 0.0 0.05 13.2 0.0 1.7 1 0 0 1 1 1 0 Homeodomain-like domain HTH_8 PF02954.14 EIE79795.1 - 0.051 13.1 0.1 0.51 9.9 0.0 2.2 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family NUP50 PF08911.6 EIE79795.1 - 0.056 13.8 1.9 0.16 12.4 1.3 1.8 1 0 0 1 1 1 0 NUP50 (Nucleoporin 50 kDa) Viral_helicase1 PF01443.13 EIE79795.1 - 0.071 12.6 0.0 0.17 11.3 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DivIC PF04977.10 EIE79797.1 - 0.0021 17.4 2.0 0.0057 16.1 1.4 1.6 1 0 0 1 1 1 1 Septum formation initiator Lebercilin PF15619.1 EIE79797.1 - 0.012 15.0 2.6 0.012 15.0 1.8 1.5 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Herpes_BLRF2 PF05812.7 EIE79797.1 - 0.017 14.9 0.1 0.033 14.0 0.1 1.5 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein SlyX PF04102.7 EIE79797.1 - 0.063 13.6 0.8 0.15 12.4 0.5 1.7 1 0 0 1 1 1 0 SlyX Cep57_CLD_2 PF14197.1 EIE79797.1 - 0.95 9.4 4.1 1 9.3 1.7 1.8 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Exotox-A_target PF09102.5 EIE79798.1 - 0.095 12.2 0.2 5.2 6.5 0.0 2.2 1 1 1 2 2 2 0 Exotoxin A, targeting DUF1798 PF08807.5 EIE79798.1 - 1.5 8.5 4.3 1.4 8.6 0.3 2.4 2 1 1 3 3 3 0 Bacterial domain of unknown function (DUF1798) RICH PF05062.7 EIE79799.1 - 0.088 12.9 2.0 1.4 9.1 0.1 2.2 2 0 0 2 2 2 0 RICH domain RVT_1 PF00078.22 EIE79800.1 - 5e-06 26.0 0.0 9.5e-06 25.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) LRR_4 PF12799.2 EIE79802.1 - 0.058 13.0 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) Ribosomal_L7Ae PF01248.21 EIE79803.1 - 6e-23 80.1 1.7 1.1e-22 79.3 1.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 EIE79803.1 - 0.013 15.3 0.2 0.025 14.3 0.1 1.5 1 1 0 1 1 1 0 RNase P subunit Pop3 Arch_ATPase PF01637.13 EIE79803.1 - 0.021 14.5 0.4 0.036 13.7 0.3 1.3 1 0 0 1 1 1 0 Archaeal ATPase THUMP PF02926.12 EIE79804.1 - 6.1e-11 42.3 1.1 8.6e-11 41.9 0.7 1.4 1 1 0 1 1 1 1 THUMP domain DUF1837 PF08878.6 EIE79804.1 - 0.037 13.6 3.8 1 8.9 0.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1837) PQ-loop PF04193.9 EIE79805.1 - 4.8e-14 51.6 1.4 7e-14 51.1 0.1 1.9 2 0 0 2 2 2 1 PQ loop repeat PAP2_C PF14360.1 EIE79805.1 - 0.011 15.9 0.8 0.029 14.6 0.5 1.7 1 1 0 1 1 1 0 PAP2 superfamily C-terminal CENP-I PF07778.6 EIE79805.1 - 0.073 11.2 0.4 0.086 11.0 0.3 1.1 1 0 0 1 1 1 0 Mis6 PPR_2 PF13041.1 EIE79806.1 - 7.2e-24 83.5 0.1 1.4e-10 40.9 0.0 4.0 3 1 1 4 4 4 3 PPR repeat family PPR PF01535.15 EIE79806.1 - 1.8e-10 40.0 0.0 0.014 15.2 0.0 5.8 6 0 0 6 6 6 2 PPR repeat PPR_3 PF13812.1 EIE79806.1 - 8.6e-10 38.1 0.0 0.13 12.5 0.0 5.7 6 0 0 6 6 6 3 Pentatricopeptide repeat domain PPR_1 PF12854.2 EIE79806.1 - 0.00011 21.6 0.0 7.1 6.2 0.0 5.0 6 0 0 6 6 6 2 PPR repeat ECSIT PF06239.6 EIE79806.1 - 0.0064 15.3 0.1 0.36 9.6 0.0 2.4 1 1 0 1 1 1 1 Evolutionarily conserved signalling intermediate in Toll pathway Malic_M PF03949.10 EIE79807.1 - 6.9e-83 278.0 0.0 1e-82 277.5 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 EIE79807.1 - 1.1e-72 243.4 0.0 1.9e-72 242.6 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Pro_isomerase PF00160.16 EIE79808.1 - 6.2e-40 136.9 1.4 6.6e-40 136.8 0.0 1.7 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ubiquitin PF00240.18 EIE79809.1 - 1.5e-14 53.0 0.3 2.6e-14 52.3 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 EIE79809.1 - 1.2e-05 25.3 0.0 2e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD PF11976.3 EIE79809.1 - 1.3e-05 24.8 0.5 2.4e-05 23.8 0.3 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 EIE79809.1 - 0.1 12.4 0.0 0.24 11.2 0.0 1.7 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Kelch_4 PF13418.1 EIE79810.1 - 1.1e-08 34.6 2.7 0.0011 18.6 0.0 3.4 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_3 PF13415.1 EIE79810.1 - 8.8e-07 28.9 3.6 0.072 13.2 0.0 3.6 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_1 PF01344.20 EIE79810.1 - 4.1e-06 26.2 4.0 0.044 13.3 0.3 3.1 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.1 EIE79810.1 - 0.00037 20.5 7.3 0.28 11.4 0.1 3.9 4 0 0 4 4 4 2 Kelch motif SKG6 PF08693.5 EIE79810.1 - 0.0027 16.9 0.4 0.0054 16.0 0.3 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4307 PF14155.1 EIE79810.1 - 0.014 15.2 0.1 0.024 14.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4307) Amnionless PF14828.1 EIE79810.1 - 0.094 11.1 0.0 0.14 10.6 0.0 1.2 1 0 0 1 1 1 0 Amnionless FGGY_C PF02782.11 EIE79811.1 - 6.5e-60 202.1 0.7 1e-59 201.5 0.5 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EIE79811.1 - 2.9e-43 147.9 0.2 1.8e-32 112.6 0.0 2.6 2 1 1 3 3 3 2 FGGY family of carbohydrate kinases, N-terminal domain Zn_clus PF00172.13 EIE79812.1 - 0.00014 21.6 16.2 0.00024 20.9 11.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DPBB_1 PF03330.13 EIE79813.1 - 2e-12 46.9 0.0 2e-12 46.9 0.0 2.3 2 1 0 2 2 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EIE79813.1 - 0.0027 17.3 0.0 0.0027 17.3 0.0 1.9 2 0 0 2 2 2 1 Barwin family AUX_IAA PF02309.11 EIE79813.1 - 0.0076 16.0 13.7 0.009 15.7 9.5 1.3 1 0 0 1 1 1 1 AUX/IAA family Borrelia_P83 PF05262.6 EIE79813.1 - 0.012 13.9 14.7 0.014 13.6 10.2 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein MIP-T3 PF10243.4 EIE79813.1 - 0.015 13.7 28.8 0.018 13.5 20.0 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 FliP PF00813.15 EIE79813.1 - 0.016 14.9 0.6 0.028 14.1 0.4 1.5 1 1 0 1 1 1 0 FliP family Mem_trans PF03547.13 EIE79813.1 - 0.04 12.2 3.7 0.037 12.3 2.6 1.2 1 0 0 1 1 1 0 Membrane transport protein MMR1 PF08505.5 EIE79813.1 - 0.054 13.5 26.4 0.074 13.0 18.3 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Mitofilin PF09731.4 EIE79813.1 - 0.061 11.9 18.9 0.068 11.8 13.1 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein SAPS PF04499.10 EIE79813.1 - 0.085 11.4 10.4 0.1 11.2 7.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DNA_pol_viral_N PF00242.12 EIE79813.1 - 0.14 11.2 26.0 0.19 10.7 18.0 1.3 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain DUF262 PF03235.9 EIE79813.1 - 0.19 11.6 5.0 0.21 11.4 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF262 CT47 PF15623.1 EIE79813.1 - 0.2 11.3 4.7 0.33 10.6 3.3 1.4 1 0 0 1 1 1 0 Cancer/testis gene family 47 Macoilin PF09726.4 EIE79813.1 - 0.36 9.0 28.7 0.41 8.8 19.9 1.0 1 0 0 1 1 1 0 Transmembrane protein SOBP PF15279.1 EIE79813.1 - 0.4 11.0 19.0 0.5 10.6 13.2 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein LMBR1 PF04791.11 EIE79813.1 - 0.44 9.0 7.4 0.44 9.0 5.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Alpha_GJ PF03229.8 EIE79813.1 - 0.68 10.2 0.0 0.68 10.2 0.0 2.5 2 1 0 2 2 2 0 Alphavirus glycoprotein J DUF572 PF04502.8 EIE79813.1 - 1 8.5 30.3 1.3 8.1 21.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF936 PF06075.7 EIE79813.1 - 1.1 8.1 24.3 1.2 7.9 16.9 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) PAP1 PF08601.5 EIE79813.1 - 1.3 8.5 27.3 1.7 8.2 18.9 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 DUF2413 PF10310.4 EIE79813.1 - 2 7.1 27.2 2.7 6.6 18.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Hid1 PF12722.2 EIE79813.1 - 2.1 5.9 17.9 2.5 5.6 12.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC45 PF02724.9 EIE79813.1 - 2.2 6.1 16.9 2.9 5.8 11.7 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF1510 PF07423.6 EIE79813.1 - 4.5 6.5 27.1 6.4 6.0 18.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2215 PF10225.4 EIE79813.1 - 4.9 6.5 8.8 6.5 6.1 6.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Spc7_N PF15402.1 EIE79813.1 - 6.5 4.6 30.0 8 4.3 20.8 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Band_3_cyto PF07565.8 EIE79813.1 - 6.7 6.1 15.9 9.3 5.6 11.0 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain HeLo PF14479.1 EIE79813.1 - 7.3 6.2 12.1 12 5.6 8.4 1.3 1 0 0 1 1 1 0 Prion-inhibition and propagation Presenilin PF01080.12 EIE79813.1 - 8.1 5.1 11.1 10 4.7 7.7 1.2 1 0 0 1 1 1 0 Presenilin Hex_IIIa PF02455.11 EIE79813.1 - 8.9 4.8 12.1 11 4.5 8.4 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Peptidase_S64 PF08192.6 EIE79813.1 - 9.1 4.4 18.8 11 4.2 13.0 1.1 1 0 0 1 1 1 0 Peptidase family S64 PBP1_TM PF14812.1 EIE79815.1 - 0.9 9.8 7.1 0.045 14.0 0.8 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RhoGEF PF00621.15 EIE79816.1 - 3.5e-18 66.1 1.0 6.2e-08 32.7 0.0 2.7 2 0 0 2 2 2 2 RhoGEF domain PH PF00169.24 EIE79816.1 - 0.00013 22.1 0.0 0.00027 21.1 0.0 1.6 1 0 0 1 1 1 1 PH domain EPL1 PF10513.4 EIE79817.1 - 2.6e-32 112.2 15.6 3.7e-32 111.7 0.9 2.9 3 0 0 3 3 3 2 Enhancer of polycomb-like DUF4604 PF15377.1 EIE79817.1 - 0.0011 19.1 5.2 0.0011 19.1 3.6 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4604) GTSE1_N PF15259.1 EIE79817.1 - 2.1 8.3 0.0 2.1 8.3 0.0 3.6 3 1 0 3 3 3 0 G-2 and S-phase expressed 1 CBM_19 PF03427.8 EIE79818.1 - 7e-36 121.8 12.8 2.2e-35 120.2 8.8 1.9 1 0 0 1 1 1 1 Carbohydrate binding domain (family 19) Glyco_hydro_18 PF00704.23 EIE79818.1 - 6e-24 85.1 1.0 4.1e-23 82.3 0.7 2.3 2 1 0 2 2 2 1 Glycosyl hydrolases family 18 DUF1168 PF06658.7 EIE79818.1 - 0.13 11.7 0.4 0.45 10.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) DUF2011 PF09428.5 EIE79819.1 - 1.4e-06 28.2 1.2 2e-06 27.7 0.4 1.6 1 1 0 1 1 1 1 Fungal protein of unknown function (DUF2011) Phage_mat-A PF03863.8 EIE79819.1 - 0.051 12.6 0.0 0.065 12.2 0.0 1.1 1 0 0 1 1 1 0 Phage maturation protein DUF4640 PF15480.1 EIE79819.1 - 0.28 10.7 7.3 0.37 10.3 5.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4640) UDPGT PF00201.13 EIE79820.1 - 1.1e-30 106.7 0.0 1.9e-30 105.9 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_trans_1_3 PF13528.1 EIE79820.1 - 4.7e-10 39.1 0.0 7.2e-05 22.1 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 1 Glyco_tran_28_C PF04101.11 EIE79820.1 - 4e-05 23.3 0.0 6.8e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_4_4 PF13579.1 EIE79820.1 - 0.009 16.1 0.0 0.42 10.7 0.0 2.9 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Chorion_2 PF03964.10 EIE79820.1 - 0.1 13.1 0.0 0.25 11.8 0.0 1.6 1 0 0 1 1 1 0 Chorion family 2 UDPGP PF01704.13 EIE79821.1 - 6e-182 604.8 1.6 7e-182 604.6 1.1 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Amidohydro_1 PF01979.15 EIE79822.1 - 5e-40 138.1 0.0 6.1e-40 137.8 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EIE79822.1 - 2.7e-05 23.8 0.0 7e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 EIE79822.1 - 2.7e-05 24.3 0.0 0.28 11.1 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_3 PF07969.6 EIE79822.1 - 6.7e-05 22.2 0.4 0.63 9.1 0.0 3.0 2 2 2 4 4 4 2 Amidohydrolase family RRM_1 PF00076.17 EIE79823.1 - 5.4e-18 64.3 0.0 1e-17 63.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE79823.1 - 3.1e-13 49.3 0.1 5.5e-12 45.3 0.0 2.5 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE79823.1 - 3.5e-09 36.5 0.0 5.1e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EIE79823.1 - 5.3e-05 23.0 0.0 8e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 RNA binding motif Nup35_RRM_2 PF14605.1 EIE79823.1 - 0.0021 17.7 0.0 0.0031 17.2 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif MFS_1 PF07690.11 EIE79824.1 - 3.6e-46 157.5 11.6 4.5e-46 157.1 8.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIE79824.1 - 5.2e-13 48.3 4.8 5.2e-13 48.3 3.3 2.6 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 EIE79824.1 - 1.4e-10 40.0 3.7 2e-10 39.5 2.6 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 EIE79824.1 - 3.9e-06 25.5 1.4 3.9e-06 25.5 1.0 2.8 2 1 1 3 3 3 2 MFS/sugar transport protein ATG22 PF11700.3 EIE79824.1 - 2.2e-05 23.1 8.8 2.2e-05 23.1 6.1 2.1 2 1 0 2 2 2 1 Vacuole effluxer Atg22 like MFS_1_like PF12832.2 EIE79824.1 - 2.2e-05 24.1 0.1 0.0094 15.7 0.0 3.3 2 0 0 2 2 2 1 MFS_1 like family DUF791 PF05631.9 EIE79824.1 - 0.00042 19.1 0.1 0.0013 17.5 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF791) OATP PF03137.15 EIE79824.1 - 3.5 5.5 8.1 0.15 10.0 1.3 1.9 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family LOH1CR12 PF10158.4 EIE79826.1 - 0.018 14.8 0.1 0.035 13.8 0.1 1.4 1 0 0 1 1 1 0 Tumour suppressor protein Hexapep PF00132.19 EIE79827.1 - 1.3e-13 49.7 12.3 6e-10 38.1 6.3 2.8 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Mac PF12464.3 EIE79827.1 - 4e-11 42.7 0.1 6.6e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep_2 PF14602.1 EIE79827.1 - 4.7e-10 38.8 12.1 1.9e-07 30.5 6.5 2.4 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Myosin_head PF00063.16 EIE79828.1 - 1.4e-235 783.5 2.6 1.4e-235 783.5 1.8 2.1 2 0 0 2 2 2 1 Myosin head (motor domain) DIL PF01843.14 EIE79828.1 - 4e-35 119.8 2.8 1.9e-34 117.7 1.9 2.3 1 0 0 1 1 1 1 DIL domain IQ PF00612.22 EIE79828.1 - 1.4e-11 42.8 25.5 0.00013 21.2 0.6 7.1 7 0 0 7 7 7 4 IQ calmodulin-binding motif AAA_22 PF13401.1 EIE79828.1 - 0.00058 19.9 0.1 0.024 14.7 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_10 PF12846.2 EIE79828.1 - 0.018 14.5 1.1 0.072 12.5 0.0 2.4 3 0 0 3 3 3 0 AAA-like domain AAA_16 PF13191.1 EIE79828.1 - 0.064 13.2 0.9 0.35 10.8 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain AAA_19 PF13245.1 EIE79828.1 - 0.064 13.0 0.2 0.28 10.9 0.0 2.1 2 0 0 2 2 2 0 Part of AAA domain ABC_tran PF00005.22 EIE79828.1 - 0.72 10.1 0.0 0.72 10.1 0.0 3.1 2 1 0 2 2 2 0 ABC transporter FUSC PF04632.7 EIE79828.1 - 0.97 7.7 2.8 1.8 6.8 1.9 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family IncA PF04156.9 EIE79828.1 - 7.1 6.1 26.8 2.8 7.4 2.0 2.9 2 1 1 3 3 3 0 IncA protein RRM_1 PF00076.17 EIE79831.1 - 1.7e-60 200.5 1.6 3e-18 65.2 0.0 5.5 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE79831.1 - 1.4e-48 162.7 0.3 9e-16 57.6 0.0 4.7 5 0 0 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE79831.1 - 1.8e-31 107.7 0.2 3.2e-09 36.4 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EIE79831.1 - 4.2e-05 23.2 0.7 1.6 8.5 0.0 4.7 4 1 0 4 4 4 2 Limkain b1 DbpA PF03880.10 EIE79831.1 - 0.006 16.2 2.1 0.058 13.0 0.0 3.0 3 0 0 3 3 3 1 DbpA RNA binding domain UEV PF05743.8 EIE79832.1 - 6.7e-40 135.5 0.2 9.2e-40 135.1 0.1 1.2 1 0 0 1 1 1 1 UEV domain zf-Mss51 PF13824.1 EIE79832.1 - 0.099 12.5 0.1 0.22 11.4 0.1 1.5 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Peptidase_M3 PF01432.15 EIE79833.1 - 1e-126 423.7 0.0 1.3e-126 423.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_MA_2 PF13485.1 EIE79833.1 - 0.072 13.1 0.2 0.22 11.5 0.0 1.9 2 0 0 2 2 2 0 Peptidase MA superfamily Peptidase_M50B PF13398.1 EIE79833.1 - 0.18 11.1 0.0 0.28 10.5 0.0 1.2 1 0 0 1 1 1 0 Peptidase M50B-like DUF2404 PF10296.4 EIE79834.1 - 6.8e-06 26.1 0.0 1.2e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) CITED PF04487.7 EIE79834.1 - 0.029 14.5 0.9 0.043 14.0 0.6 1.2 1 0 0 1 1 1 0 CITED SF3a60_bindingd PF12108.3 EIE79834.1 - 0.16 11.4 0.8 0.65 9.5 0.1 2.2 2 0 0 2 2 2 0 Splicing factor SF3a60 binding domain FGGY_C PF02782.11 EIE79835.1 - 1.2e-09 38.0 0.0 1.5e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Metallophos PF00149.23 EIE79837.1 - 8.4e-41 139.5 0.1 1.1e-40 139.1 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Methyltransf_16 PF10294.4 EIE79838.1 - 8.1e-22 77.4 0.0 1e-21 77.1 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EIE79838.1 - 1.9e-05 25.1 0.0 4.4e-05 24.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIE79838.1 - 7e-05 22.5 0.0 0.00011 21.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIE79838.1 - 0.011 16.1 0.0 0.03 14.7 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 EIE79838.1 - 0.018 14.1 0.0 0.026 13.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 EIE79838.1 - 0.018 14.6 0.0 0.031 13.8 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 EIE79838.1 - 0.035 14.5 0.0 0.068 13.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EIE79838.1 - 0.06 12.7 0.0 0.11 11.8 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase small domain UDPGT PF00201.13 EIE79839.1 - 5.7e-31 107.6 0.0 1.6e-29 102.8 0.0 2.1 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_trans_1_3 PF13528.1 EIE79839.1 - 1.3e-09 37.7 0.0 0.00013 21.3 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 1 Glyco_tran_28_C PF04101.11 EIE79839.1 - 0.00019 21.1 0.0 0.00032 20.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_4_4 PF13579.1 EIE79839.1 - 0.029 14.5 0.0 0.99 9.5 0.0 2.5 2 1 0 2 2 2 0 Glycosyl transferase 4-like domain Stanniocalcin PF03298.8 EIE79840.1 - 0.0023 16.9 0.1 0.0062 15.5 0.1 1.7 1 0 0 1 1 1 1 Stanniocalcin family DUF4298 PF14131.1 EIE79840.1 - 0.16 11.8 10.3 0.55 10.1 0.2 4.2 3 2 1 4 4 4 0 Domain of unknown function (DUF4298) DUF2340 PF10209.4 EIE79840.1 - 0.26 11.4 2.9 5.9 7.0 0.1 3.3 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2340) DUF2207 PF09972.4 EIE79841.1 - 0.26 9.8 1.9 0.19 10.2 0.3 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) SHP PF03579.8 EIE79841.1 - 4.3 6.7 8.1 0.83 9.0 1.3 2.7 2 0 0 2 2 2 0 Small hydrophobic protein ABA_GPCR PF12430.3 EIE79842.1 - 3.8e-42 143.6 11.5 4.5e-42 143.4 8.0 1.0 1 0 0 1 1 1 1 Abscisic acid G-protein coupled receptor PIG-P PF08510.7 EIE79842.1 - 6.9 6.3 9.1 1.4 8.5 3.8 1.8 2 1 0 2 2 2 0 PIG-P Ras PF00071.17 EIE79843.1 - 2.4e-60 202.5 0.3 2.9e-60 202.3 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIE79843.1 - 1e-19 71.1 0.0 1.6e-19 70.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIE79843.1 - 1.3e-08 34.2 0.0 1.6e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EIE79843.1 - 5.4e-05 22.7 0.0 8.8e-05 22.0 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EIE79843.1 - 0.013 15.4 0.0 0.016 15.1 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase FeoB_N PF02421.13 EIE79843.1 - 0.014 14.6 0.1 0.041 13.1 0.1 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B Gtr1_RagA PF04670.7 EIE79843.1 - 0.082 12.0 0.1 0.11 11.6 0.1 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region TcdB_N PF12918.2 EIE79843.1 - 0.083 12.9 1.3 0.28 11.2 0.3 2.2 2 0 0 2 2 2 0 TcdB toxin N-terminal helical domain 2Fe-2S_thioredx PF01257.14 EIE79843.1 - 0.096 12.2 0.1 0.14 11.7 0.1 1.3 1 0 0 1 1 1 0 Thioredoxin-like [2Fe-2S] ferredoxin DUF258 PF03193.11 EIE79843.1 - 0.14 11.3 0.7 0.23 10.6 0.1 1.8 2 1 0 2 2 2 0 Protein of unknown function, DUF258 LRR_4 PF12799.2 EIE79844.1 - 0.003 17.1 10.1 1.2 8.7 0.0 4.8 2 1 3 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EIE79844.1 - 0.2 11.4 12.9 0.61 9.8 1.0 4.2 2 1 2 4 4 4 0 Leucine rich repeat FNIP PF05725.7 EIE79844.1 - 0.89 9.5 4.8 11 6.0 1.6 2.8 2 1 0 2 2 2 0 FNIP Repeat RED_N PF07808.8 EIE79845.1 - 7e-35 120.3 8.6 7e-35 120.3 6.0 3.4 3 2 0 3 3 3 1 RED-like protein N-terminal region RED_C PF07807.6 EIE79845.1 - 5.1e-22 78.2 6.6 5.1e-22 78.2 4.5 2.7 3 0 0 3 3 3 1 RED-like protein C-terminal region Glyco_hydro_35 PF01301.14 EIE79846.1 - 4.9e-35 121.4 0.2 3.5e-16 59.4 0.0 2.3 1 1 1 2 2 2 2 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.1 EIE79846.1 - 3.4e-07 30.5 0.3 0.0038 17.4 0.0 2.7 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain RasGEF PF00617.14 EIE79847.1 - 2.5e-42 144.7 0.2 4.2e-42 144.0 0.1 1.3 1 0 0 1 1 1 1 RasGEF domain FliJ PF02050.11 EIE79847.1 - 0.15 12.1 1.0 0.4 10.7 0.0 2.2 2 0 0 2 2 2 0 Flagellar FliJ protein GPI-anchored PF10342.4 EIE79848.1 - 2.1e-11 44.1 0.6 2.1e-11 44.1 0.4 2.4 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Zn_clus PF00172.13 EIE79849.1 - 4.6e-10 39.2 22.7 4.7e-06 26.4 6.3 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box PF00646.28 EIE79850.1 - 0.022 14.4 0.4 0.056 13.1 0.3 1.7 1 0 0 1 1 1 0 F-box domain SDA1 PF05285.7 EIE79850.1 - 0.12 11.6 1.0 0.18 11.0 0.7 1.2 1 0 0 1 1 1 0 SDA1 F-box-like PF12937.2 EIE79850.1 - 3.4 7.4 7.6 0.47 10.2 0.8 2.6 3 0 0 3 3 3 0 F-box-like SHD1 PF03983.7 EIE79851.1 - 4.2e-09 35.9 0.0 1.1e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 F-box-like PF12937.2 EIE79851.1 - 1e-05 25.1 0.1 8.6e-05 22.1 0.0 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EIE79851.1 - 9.5e-05 21.9 0.1 0.0013 18.3 0.1 2.6 2 0 0 2 2 2 1 F-box domain Glyco_hydro_3 PF00933.16 EIE79852.1 - 9.2e-85 284.2 0.0 1.3e-84 283.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EIE79852.1 - 1.4e-63 214.5 0.3 2.3e-63 213.7 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EIE79852.1 - 6.7e-22 77.2 0.0 1.5e-21 76.1 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_3 PF00933.16 EIE79853.1 - 1e-87 293.9 0.0 1.5e-87 293.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EIE79853.1 - 2.5e-63 213.6 0.4 4.9e-63 212.6 0.2 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EIE79853.1 - 7.5e-22 77.0 0.0 1.5e-21 76.1 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain FYRN PF05964.9 EIE79854.1 - 4.6e-19 67.6 1.3 9.4e-19 66.6 0.9 1.6 1 0 0 1 1 1 1 F/Y-rich N-terminus FYRC PF05965.9 EIE79854.1 - 7.5e-16 57.7 0.0 1.7e-15 56.6 0.0 1.6 1 0 0 1 1 1 1 F/Y rich C-terminus Galactosyl_T PF01762.16 EIE79855.1 - 1.5e-14 54.0 0.0 2.2e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase EOS1 PF12326.3 EIE79855.1 - 3.5e-12 46.1 10.0 7.7e-12 45.0 6.9 1.6 1 0 0 1 1 1 1 N-glycosylation protein Fungal_trans PF04082.13 EIE79857.1 - 8.9e-30 103.4 2.4 9.6e-30 103.3 0.4 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIE79857.1 - 2.6e-09 36.8 12.8 5e-09 35.9 8.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4377 PF14302.1 EIE79858.1 - 0.023 14.5 0.2 0.054 13.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4377) AA_kinase PF00696.23 EIE79860.1 - 3.4e-42 144.6 0.2 5.8e-42 143.8 0.1 1.4 1 0 0 1 1 1 1 Amino acid kinase family ACT PF01842.20 EIE79860.1 - 2.1e-13 49.4 0.7 8.2e-08 31.5 0.1 2.8 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.1 EIE79860.1 - 1.4e-12 46.9 2.8 2e-09 36.8 0.7 2.7 2 0 0 2 2 2 2 ACT domain DUF334 PF03904.8 EIE79860.1 - 0.038 13.3 0.1 0.063 12.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF334) DUF3408 PF11888.3 EIE79860.1 - 0.066 13.1 1.7 7.6 6.4 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3408) Abhydrolase_1 PF00561.15 EIE79861.1 - 5e-22 78.5 0.0 1.1e-19 70.8 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EIE79861.1 - 1.9e-13 50.8 0.2 9.3e-13 48.5 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EIE79861.1 - 0.002 17.6 0.0 0.004 16.6 0.0 1.5 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 EIE79861.1 - 0.0033 17.1 0.0 0.38 10.4 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family AMP-binding PF00501.23 EIE79862.1 - 1.2e-45 155.6 0.0 1.9e-45 155.0 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EIE79862.1 - 1.6e-39 135.3 0.0 4e-39 134.0 0.0 1.7 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 EIE79862.1 - 1.2e-07 31.8 0.0 2.3e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 EIE79862.1 - 0.0042 16.5 0.0 0.01 15.2 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EIE79862.1 - 0.012 15.4 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EIE79862.1 - 0.051 12.4 0.0 0.088 11.6 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NmrA PF05368.8 EIE79862.1 - 0.06 12.6 0.0 0.15 11.2 0.0 1.7 2 0 0 2 2 2 0 NmrA-like family KR PF08659.5 EIE79862.1 - 0.093 12.3 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 KR domain DDE_3 PF13358.1 EIE79863.1 - 8.9e-30 103.3 0.0 1.7e-29 102.4 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE79863.1 - 0.0011 19.0 0.0 0.0039 17.2 0.0 1.9 1 1 0 1 1 1 1 Integrase core domain Complex1_LYR PF05347.10 EIE79864.1 - 3.4e-05 23.5 0.4 5.8e-05 22.8 0.3 1.4 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.1 EIE79864.1 - 0.0003 21.2 0.2 0.00038 20.8 0.2 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.1 EIE79864.1 - 0.00074 19.6 0.6 0.0016 18.6 0.4 1.6 1 1 0 1 1 1 1 Complex1_LYR-like RhoGEF PF00621.15 EIE79865.1 - 1.6e-05 24.9 0.5 3.6e-05 23.7 0.4 1.5 1 0 0 1 1 1 1 RhoGEF domain PRP1_N PF06424.7 EIE79865.1 - 1 9.6 12.8 0.089 13.1 1.8 2.4 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal Afi1 PF07792.7 EIE79865.1 - 1.9 8.4 6.6 0.36 10.8 0.8 2.1 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Ras PF00071.17 EIE79867.1 - 2.3e-56 189.6 0.0 2.7e-56 189.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIE79867.1 - 3.3e-15 56.6 0.0 4.9e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIE79867.1 - 3.8e-07 29.4 0.0 6.2e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EIE79867.1 - 0.0074 15.5 0.0 0.01 15.0 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EIE79867.1 - 0.14 11.2 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Glyco_hydro_3_C PF01915.17 EIE79869.1 - 1.8e-07 30.9 2.1 2.2e-06 27.3 0.7 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 3 C-terminal domain Pkinase PF00069.20 EIE79870.1 - 1.1e-69 234.4 0.0 1.5e-69 234.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE79870.1 - 3.1e-37 128.0 0.0 4.2e-37 127.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE79870.1 - 0.00095 18.2 0.0 0.0024 16.8 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 EIE79870.1 - 0.064 12.9 0.0 0.14 11.8 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Paramyxo_C PF01692.13 EIE79870.1 - 0.4 10.2 2.6 0.53 9.8 1.8 1.2 1 0 0 1 1 1 0 Paramyxovirus non-structural protein c Sugar_tr PF00083.19 EIE79871.1 - 2.9e-129 431.5 31.6 3.7e-129 431.2 21.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIE79871.1 - 6.5e-35 120.4 66.9 8.7e-30 103.6 22.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily RVT_1 PF00078.22 EIE79872.1 - 1.4e-37 129.1 0.0 2e-37 128.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_3 PF13358.1 EIE79873.1 - 2.1e-26 92.3 0.0 3.5e-26 91.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE79873.1 - 0.034 14.2 0.0 0.2 11.7 0.0 2.1 2 0 0 2 2 2 0 Integrase core domain RRM_1 PF00076.17 EIE79874.1 - 0.11 12.0 1.8 0.78 9.4 0.0 3.1 4 0 0 4 4 4 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.18 EIE79874.1 - 0.44 10.5 2.7 1.3 9.1 0.2 2.2 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.1 EIE79874.1 - 2.4 7.9 9.3 0.54 9.9 0.5 3.0 3 0 0 3 3 3 0 Zinc knuckle Inhibitor_I10 PF12559.3 EIE79876.1 - 0.17 12.2 1.3 0.97 9.7 0.0 2.3 2 0 0 2 2 2 0 Serine endopeptidase inhibitors RVT_1 PF00078.22 EIE79878.1 - 1.9e-27 96.0 0.0 3e-27 95.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Zn_Tnp_IS1 PF03811.8 EIE79879.1 - 0.007 15.8 4.6 0.014 14.8 3.2 1.5 1 0 0 1 1 1 1 InsA N-terminal domain Prefoldin_2 PF01920.15 EIE79879.1 - 0.066 12.9 0.4 0.18 11.5 0.3 1.7 1 0 0 1 1 1 0 Prefoldin subunit Phlebovirus_NSM PF07246.6 EIE79879.1 - 0.072 12.2 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M FlaC_arch PF05377.6 EIE79879.1 - 0.11 12.4 0.6 0.27 11.1 0.4 1.7 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) zf-H2C2_2 PF13465.1 EIE79879.1 - 0.12 12.6 4.3 1.4 9.2 0.4 2.6 2 0 0 2 2 2 0 Zinc-finger double domain Zn-ribbon_8 PF09723.5 EIE79879.1 - 0.15 12.0 2.6 6.7 6.7 0.7 2.5 2 0 0 2 2 2 0 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 EIE79879.1 - 0.31 10.8 2.2 0.6 9.9 1.6 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-DNA_Pol PF08996.5 EIE79879.1 - 0.86 8.9 5.3 0.24 10.7 1.4 1.6 2 0 0 2 2 2 0 DNA Polymerase alpha zinc finger zf-ISL3 PF14690.1 EIE79879.1 - 3 7.9 5.6 0.48 10.5 0.3 2.2 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zinc_ribbon_5 PF13719.1 EIE79879.1 - 4.3 6.9 5.5 9.4 5.9 0.6 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Inhibitor_I10 PF12559.3 EIE79880.1 - 0.17 12.2 1.3 0.97 9.7 0.0 2.3 2 0 0 2 2 2 0 Serine endopeptidase inhibitors DDE_3 PF13358.1 EIE79882.1 - 5.6e-23 81.3 0.1 3e-18 65.9 0.0 2.1 1 1 1 2 2 2 2 DDE superfamily endonuclease DDE_1 PF03184.14 EIE79882.1 - 0.045 12.8 0.0 0.49 9.4 0.0 1.9 2 0 0 2 2 2 0 DDE superfamily endonuclease MSC PF09402.5 EIE79883.1 - 8.2e-31 106.9 0.2 2.4e-30 105.4 0.0 1.8 1 1 1 2 2 2 2 Man1-Src1p-C-terminal domain HeH PF12949.2 EIE79883.1 - 0.0088 15.5 0.0 0.021 14.3 0.0 1.7 1 0 0 1 1 1 1 HeH/LEM domain Endonuc-dimeris PF09124.5 EIE79883.1 - 0.08 12.5 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 T4 recombination endonuclease VII, dimerisation SDA1 PF05285.7 EIE79883.1 - 2.6 7.2 21.5 5.3 6.2 14.9 1.5 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 EIE79883.1 - 7.6 4.3 26.4 12 3.7 18.3 1.2 1 0 0 1 1 1 0 Nop14-like family DUF4446 PF14584.1 EIE79884.1 - 0.0043 16.8 0.6 0.0087 15.8 0.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4446) Phage_Mu_Gam PF07352.7 EIE79884.1 - 0.021 14.3 2.1 0.042 13.3 0.3 2.0 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein AAA_13 PF13166.1 EIE79884.1 - 0.021 13.2 3.7 0.027 12.9 2.5 1.0 1 0 0 1 1 1 0 AAA domain P4Ha_N PF08336.6 EIE79884.1 - 0.027 14.2 2.2 0.064 13.0 0.2 2.2 1 1 1 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region FliD_C PF07195.7 EIE79884.1 - 0.034 13.4 0.2 0.039 13.2 0.1 1.2 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus FRD2 PF03197.8 EIE79884.1 - 0.047 14.2 0.2 0.075 13.5 0.1 1.3 1 0 0 1 1 1 0 Bacteriophage FRD2 protein BMFP PF04380.8 EIE79884.1 - 0.053 13.6 0.6 0.13 12.4 0.2 1.9 2 0 0 2 2 1 0 Membrane fusogenic activity ApoLp-III PF07464.6 EIE79884.1 - 0.098 12.6 3.8 0.14 12.2 2.4 1.3 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) KfrA_N PF11740.3 EIE79884.1 - 0.15 12.5 1.2 0.22 12.0 0.1 1.7 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term Spectrin PF00435.16 EIE79884.1 - 0.2 11.9 4.6 7.2 6.9 0.0 2.5 2 1 0 2 2 2 0 Spectrin repeat Ax_dynein_light PF10211.4 EIE79884.1 - 0.26 11.1 4.3 0.28 10.9 2.2 1.6 1 1 0 1 1 1 0 Axonemal dynein light chain TPR_MLP1_2 PF07926.7 EIE79884.1 - 0.26 11.0 4.2 5.6 6.7 0.5 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein IPP-2 PF04979.9 EIE79884.1 - 0.27 11.4 3.3 0.45 10.7 1.8 1.6 1 1 1 2 2 2 0 Protein phosphatase inhibitor 2 (IPP-2) Snapin_Pallidin PF14712.1 EIE79884.1 - 0.49 10.7 2.4 1.8 8.9 0.2 2.7 1 1 2 3 3 3 0 Snapin/Pallidin Cytochrom_B562 PF07361.6 EIE79884.1 - 0.75 10.2 5.4 0.59 10.5 0.2 2.2 1 1 1 2 2 2 0 Cytochrome b562 Remorin_C PF03763.8 EIE79884.1 - 1.1 8.8 4.6 4.8 6.7 2.3 2.3 1 1 1 2 2 2 0 Remorin, C-terminal region Cep57_CLD_2 PF14197.1 EIE79884.1 - 2.5 8.1 6.1 2.6 8.0 0.0 3.0 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 HlyIII PF03006.15 EIE79885.1 - 2.1e-25 89.4 8.5 2.4e-25 89.2 5.9 1.0 1 0 0 1 1 1 1 Haemolysin-III related TFIID-18kDa PF02269.11 EIE79886.1 - 8.6e-14 51.1 0.7 3.8e-13 49.0 0.2 2.2 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit SHR3_chaperone PF08229.6 EIE79887.1 - 0.03 13.2 0.3 0.071 12.0 0.1 1.7 2 0 0 2 2 2 0 ER membrane protein SH3 DUF4218 PF13960.1 EIE79887.1 - 0.056 12.8 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) ABC_membrane PF00664.18 EIE79889.1 - 5.4e-48 163.7 2.2 9.3e-48 162.9 1.5 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EIE79889.1 - 9e-37 126.4 0.0 2.5e-36 125.0 0.0 1.8 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EIE79889.1 - 1.2e-05 25.4 0.2 0.097 12.6 0.2 2.4 1 1 0 2 2 2 2 AAA domain SMC_N PF02463.14 EIE79889.1 - 1.5e-05 24.2 0.5 0.0058 15.8 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EIE79889.1 - 0.00019 22.2 0.0 0.00039 21.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EIE79889.1 - 0.00093 19.3 0.4 0.019 15.0 0.3 2.6 2 1 0 2 2 1 1 AAA domain AAA_25 PF13481.1 EIE79889.1 - 0.0018 17.6 0.3 0.1 11.9 0.1 2.5 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EIE79889.1 - 0.0023 18.2 0.0 0.0049 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EIE79889.1 - 0.0029 17.5 0.1 0.0082 16.1 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 EIE79889.1 - 0.0051 16.3 0.6 0.014 14.9 0.4 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF2075 PF09848.4 EIE79889.1 - 0.017 14.1 0.0 0.028 13.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_10 PF12846.2 EIE79889.1 - 0.027 13.9 0.2 3 7.2 0.1 2.4 2 0 0 2 2 2 0 AAA-like domain DUF258 PF03193.11 EIE79889.1 - 0.038 13.1 0.1 0.12 11.5 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function, DUF258 DUF87 PF01935.12 EIE79889.1 - 0.078 12.7 0.1 0.2 11.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF87 Zeta_toxin PF06414.7 EIE79889.1 - 0.085 11.9 0.0 0.66 9.0 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin AAA_23 PF13476.1 EIE79889.1 - 0.12 12.7 0.2 0.3 11.3 0.1 1.6 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 EIE79889.1 - 0.2 11.5 1.4 0.86 9.5 0.2 2.5 2 1 0 2 2 1 0 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.1 EIE79889.1 - 0.2 11.5 0.7 0.74 9.6 0.5 2.0 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EIE79889.1 - 0.41 10.1 2.8 2.5 7.6 0.6 2.7 2 1 0 2 2 2 0 AAA domain Iso_dh PF00180.15 EIE79890.1 - 1.9e-82 276.9 0.1 2.5e-82 276.6 0.1 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase YopJ PF03421.11 EIE79890.1 - 0.14 12.0 0.7 10 5.9 0.1 2.2 2 0 0 2 2 2 0 YopJ Serine/Threonine acetyltransferase M20_dimer PF07687.9 EIE79891.1 - 1.8e-10 40.5 0.0 3.4e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.23 EIE79891.1 - 7.6e-05 22.2 0.0 9.9e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Arrestin_C PF02752.17 EIE79894.1 - 5.9e-09 36.1 0.0 1.6e-08 34.7 0.0 1.7 1 1 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain TIP41 PF04176.8 EIE79894.1 - 0.05 12.8 0.2 0.085 12.1 0.1 1.3 1 0 0 1 1 1 0 TIP41-like family WD40 PF00400.27 EIE79897.1 - 4.2e-69 226.1 14.4 7.6e-13 47.8 0.2 7.5 8 0 0 8 8 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EIE79897.1 - 7.7e-12 45.3 0.2 0.0021 17.8 0.0 3.7 1 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 EIE79897.1 - 0.0028 17.1 0.0 1.1 8.8 0.0 4.3 5 0 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Hom_end_hint PF05203.11 EIE79897.1 - 0.016 14.9 0.1 0.018 14.7 0.1 1.2 1 0 0 1 1 1 0 Hom_end-associated Hint Nbas_N PF15492.1 EIE79897.1 - 0.049 12.7 0.1 0.44 9.6 0.0 2.5 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal FYDLN_acid PF09538.5 EIE79897.1 - 0.066 13.8 9.2 0.13 12.8 6.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) DUF1510 PF07423.6 EIE79897.1 - 0.13 11.6 10.1 0.076 12.3 5.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Ycf1 PF05758.7 EIE79897.1 - 0.2 9.3 2.3 0.24 9.0 1.6 1.1 1 0 0 1 1 1 0 Ycf1 Tom22 PF04281.8 EIE79897.1 - 0.24 10.9 5.2 0.43 10.0 3.6 1.3 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 NARP1 PF12569.3 EIE79897.1 - 1.9 7.1 8.7 2.8 6.5 6.1 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF3987 PF13148.1 EIE79897.1 - 2.6 6.5 5.7 4.8 5.6 4.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) PBP1_TM PF14812.1 EIE79897.1 - 3.4 8.0 11.0 5.8 7.2 7.6 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NPR3 PF03666.8 EIE79897.1 - 6.1 5.2 6.5 8.5 4.7 4.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Atg14 PF10186.4 EIE79898.1 - 1.8e-19 69.8 0.0 2.4e-19 69.3 0.0 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 Sel1 PF08238.7 EIE79899.1 - 2.6e-38 129.5 29.2 3.2e-08 33.9 0.2 7.6 8 0 0 8 8 8 7 Sel1 repeat TPR_6 PF13174.1 EIE79899.1 - 0.093 13.2 12.3 0.84 10.2 0.2 5.9 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_19 PF14559.1 EIE79899.1 - 0.097 13.0 2.3 15 6.0 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 EIE79899.1 - 0.78 9.7 8.6 1.8 8.5 0.0 4.6 2 1 4 6 6 6 0 Tetratricopeptide repeat Xin PF08043.7 EIE79900.1 - 0.14 11.8 0.3 0.28 10.9 0.0 1.7 2 0 0 2 2 2 0 Xin repeat DUF2046 PF09755.4 EIE79901.1 - 2.8e-30 105.2 23.3 2.8e-30 105.2 16.1 2.9 1 1 2 3 3 3 1 Uncharacterized conserved protein H4 (DUF2046) UPF0114 PF03350.11 EIE79901.1 - 0.12 12.2 0.3 0.26 11.2 0.2 1.5 1 0 0 1 1 1 0 Uncharacterized protein family, UPF0114 Apo-CIII PF05778.7 EIE79901.1 - 0.34 10.3 3.2 6.9 6.1 0.1 2.9 1 1 1 2 2 2 0 Apolipoprotein CIII (Apo-CIII) TMV_coat PF00721.16 EIE79902.1 - 0.0085 16.0 0.1 0.016 15.1 0.1 1.5 1 1 0 1 1 1 1 Virus coat protein (TMV like) AMP-binding PF00501.23 EIE79903.1 - 1.9e-86 290.0 0.0 2.9e-86 289.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Methyltransf_11 PF08241.7 EIE79904.1 - 8.9e-09 35.7 0.0 1.7e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIE79904.1 - 2.1e-05 24.1 0.0 0.00029 20.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_8 PF05148.10 EIE79904.1 - 0.00083 19.0 0.0 0.001 18.7 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase Ubie_methyltran PF01209.13 EIE79904.1 - 0.00087 18.4 0.0 0.0019 17.3 0.0 1.5 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EIE79904.1 - 0.0019 18.6 0.0 0.0066 16.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIE79904.1 - 0.0039 16.9 0.0 0.0057 16.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIE79904.1 - 0.062 13.6 0.0 0.17 12.2 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Ank_4 PF13637.1 EIE79905.1 - 1.8e-15 56.9 0.1 1.3e-07 31.8 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EIE79905.1 - 1.8e-13 50.6 0.1 3.2e-13 49.8 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EIE79905.1 - 1.3e-10 40.5 0.4 5.7e-06 25.8 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EIE79905.1 - 5.4e-09 36.0 0.1 4.2e-06 26.8 0.0 3.1 1 1 2 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIE79905.1 - 6.4e-09 35.2 0.3 7.7e-06 25.6 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat RecX PF02631.11 EIE79905.1 - 0.059 13.5 0.2 0.059 13.5 0.1 1.9 2 1 0 2 2 2 0 RecX family DUF1451 PF07295.6 EIE79905.1 - 0.11 12.2 4.7 0.41 10.4 3.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1451) DUF4406 PF14359.1 EIE79905.1 - 0.16 12.0 0.8 0.29 11.2 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4406) XH PF03469.9 EIE79905.1 - 0.7 9.5 9.9 1.7 8.3 0.2 2.2 2 0 0 2 2 2 0 XH domain Ribosomal_L18e PF00828.14 EIE79906.1 - 1.9e-24 86.4 0.1 2.1e-24 86.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Plant_tran PF04827.9 EIE79908.1 - 2.5e-51 173.9 0.3 5.6e-51 172.8 0.2 1.5 1 1 0 1 1 1 1 Plant transposon protein DDE_Tnp_4 PF13359.1 EIE79908.1 - 2e-08 34.0 0.0 3e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Iso_dh PF00180.15 EIE79909.1 - 8e-100 334.1 0.0 9.2e-100 333.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Aminotran_3 PF00202.16 EIE79910.1 - 7e-91 304.5 0.0 8.2e-91 304.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EIE79910.1 - 0.0025 16.8 0.0 0.011 14.6 0.0 2.1 2 1 0 2 2 2 1 Aminotransferase class I and II Nramp PF01566.13 EIE79911.1 - 6.6e-80 268.5 12.7 1.1e-78 264.5 8.8 2.5 1 1 0 1 1 1 1 Natural resistance-associated macrophage protein Ferric_reduct PF01794.14 EIE79912.1 - 4.8e-17 62.2 8.1 4.8e-17 62.2 5.6 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EIE79912.1 - 1.1e-12 48.1 0.1 2.2e-05 24.3 0.0 2.4 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EIE79912.1 - 2.1e-08 33.9 0.0 3e-05 23.8 0.0 2.5 2 0 0 2 2 2 2 FAD-binding domain Wzy_C PF04932.10 EIE79912.1 - 0.028 14.2 3.1 3.1 7.5 0.0 3.0 3 0 0 3 3 3 0 O-Antigen ligase NAD_binding_1 PF00175.16 EIE79912.1 - 0.051 14.1 0.0 0.64 10.6 0.0 2.3 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain zf-C2H2_2 PF12756.2 EIE79913.1 - 2.5e-06 27.5 0.3 4.1e-06 26.8 0.2 1.4 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.1 EIE79913.1 - 0.00062 19.8 5.3 0.046 13.9 0.1 2.6 2 0 0 2 2 2 2 C2H2-type zinc-finger domain DUF4451 PF14616.1 EIE79913.1 - 0.0027 17.4 2.4 0.25 11.1 0.2 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4451) zf-C2H2 PF00096.21 EIE79913.1 - 0.073 13.4 0.3 0.073 13.4 0.2 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF1059 PF06348.6 EIE79913.1 - 0.079 12.7 0.4 11 5.9 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1059) zf-C2H2_4 PF13894.1 EIE79913.1 - 0.082 13.2 7.7 0.11 12.8 0.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger Sporozoite_P67 PF05642.6 EIE79913.1 - 0.17 9.7 0.7 0.18 9.6 0.5 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen tRNA-synt_2 PF00152.15 EIE79914.1 - 3.4e-84 282.5 0.6 5.2e-84 281.8 0.4 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EIE79914.1 - 0.0004 20.1 1.2 0.00083 19.1 0.8 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EIE79914.1 - 0.0026 16.9 1.0 1.2 8.2 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Kelch_3 PF13415.1 EIE79915.1 - 2.8e-29 100.5 7.7 4.7e-09 36.1 0.0 7.0 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_4 PF13418.1 EIE79915.1 - 2.9e-26 90.9 6.0 2.5e-10 39.9 0.0 4.8 4 1 1 5 5 5 3 Galactose oxidase, central domain Kelch_1 PF01344.20 EIE79915.1 - 2e-25 88.0 1.2 2.5e-08 33.3 0.0 4.5 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.1 EIE79915.1 - 1.1e-23 82.3 1.5 7.9e-08 32.1 0.0 4.8 2 1 2 4 4 4 4 Kelch motif Kelch_5 PF13854.1 EIE79915.1 - 1.5e-21 75.8 0.1 1e-07 31.7 0.0 4.6 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.10 EIE79915.1 - 1.4e-18 65.8 2.2 3.4e-06 26.5 0.0 4.7 5 0 0 5 5 5 4 Kelch motif Endostatin PF06482.6 EIE79915.1 - 0.37 10.1 7.4 0.58 9.5 5.1 1.3 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Presenilin PF01080.12 EIE79916.1 - 2.8 6.6 6.9 3.2 6.4 4.8 1.1 1 0 0 1 1 1 0 Presenilin HSP70 PF00012.15 EIE79917.1 - 3.3e-105 352.2 2.5 3.3e-105 352.2 1.7 1.6 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 EIE79917.1 - 5.5e-14 51.4 1.5 7.5e-14 51.0 0.4 1.6 2 0 0 2 2 2 1 MreB/Mbl protein PilM_2 PF11104.3 EIE79917.1 - 1.8e-05 23.7 0.5 5.7e-05 22.1 0.3 1.8 1 1 0 1 1 1 1 Type IV pilus assembly protein PilM; Metallopep PF12044.3 EIE79918.1 - 1.7e-08 33.3 0.0 3.4e-08 32.3 0.0 1.5 2 0 0 2 2 2 1 Putative peptidase family Jacalin PF01419.12 EIE79918.1 - 3.2e-07 30.3 0.2 1.6e-06 28.0 0.0 2.1 2 1 0 2 2 2 1 Jacalin-like lectin domain SET PF00856.23 EIE79919.1 - 2.6e-07 31.0 0.1 1.2e-06 28.9 0.0 1.9 2 0 0 2 2 2 1 SET domain SAF PF08666.7 EIE79919.1 - 0.11 12.9 0.0 1.1 9.7 0.0 2.2 2 0 0 2 2 2 0 SAF domain Methyltransf_11 PF08241.7 EIE79920.1 - 2.4e-09 37.5 0.0 5.5e-09 36.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIE79920.1 - 0.00014 22.3 0.0 0.00027 21.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIE79920.1 - 0.00027 20.6 0.0 0.00032 20.4 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIE79920.1 - 0.00067 18.8 0.0 0.0011 18.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EIE79920.1 - 0.0014 18.2 0.0 0.003 17.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EIE79920.1 - 0.051 13.1 0.0 0.082 12.5 0.0 1.4 1 0 0 1 1 1 0 Hypothetical methyltransferase DASH_Spc34 PF08657.5 EIE79920.1 - 0.066 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 DASH complex subunit Spc34 MerB PF03243.10 EIE79920.1 - 2.5 7.9 5.4 16 5.3 0.3 2.5 2 1 1 3 3 3 0 Alkylmercury lyase Acyl-CoA_dh_M PF02770.14 EIE79921.1 - 0.00041 19.8 0.0 0.00083 18.8 0.0 1.5 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain SLX9 PF15341.1 EIE79923.1 - 9e-17 61.6 14.1 9e-17 61.6 9.8 1.7 2 0 0 2 2 2 1 Ribosome biogenesis protein SLX9 Arf PF00025.16 EIE79923.1 - 0.14 11.3 5.4 0.28 10.3 0.6 2.3 1 1 1 2 2 2 0 ADP-ribosylation factor family Alk_phosphatase PF00245.15 EIE79925.1 - 4.5e-60 203.5 1.8 8.5e-60 202.6 1.2 1.4 1 1 0 1 1 1 1 Alkaline phosphatase Sulfatase PF00884.18 EIE79925.1 - 3.5e-06 26.4 0.0 3.2e-05 23.2 0.0 2.3 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 EIE79925.1 - 0.0001 21.8 2.5 0.00018 20.9 1.3 1.7 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase RRM_1 PF00076.17 EIE79926.1 - 7.2e-17 60.7 0.0 1.3e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE79926.1 - 5.4e-12 45.5 0.0 9.6e-12 44.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE79926.1 - 5.6e-09 35.7 0.1 1e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3227 PF11537.3 EIE79926.1 - 0.0086 16.1 0.7 0.014 15.4 0.3 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3227) Nup35_RRM_2 PF14605.1 EIE79926.1 - 0.088 12.5 0.1 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Ribosomal_L34e PF01199.13 EIE79931.1 - 7.6e-41 138.2 6.0 9.2e-41 137.9 4.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L34e GFA PF04828.9 EIE79931.1 - 0.093 12.6 0.7 0.33 10.9 0.0 1.9 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme TPR_11 PF13414.1 EIE79932.1 - 6.5e-12 44.9 4.0 3.1e-11 42.7 2.1 2.4 2 1 1 3 3 3 1 TPR repeat TPR_12 PF13424.1 EIE79932.1 - 5.7e-09 35.7 6.1 5.5e-05 23.0 1.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 EIE79932.1 - 4.6e-08 32.3 11.2 9.7e-06 24.9 0.2 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EIE79932.1 - 8.2e-07 28.4 9.0 0.0022 17.7 0.1 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 EIE79932.1 - 3.5e-06 26.7 0.3 1.8e-05 24.5 0.1 1.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 EIE79932.1 - 1.2e-05 25.1 1.0 4.2e-05 23.4 0.4 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 EIE79932.1 - 3.8e-05 23.1 5.2 0.00016 21.1 0.2 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EIE79932.1 - 0.0008 20.0 0.7 0.0015 19.1 0.3 1.6 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.1 EIE79932.1 - 0.0013 18.9 0.9 0.003 17.8 0.6 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat NARP1 PF12569.3 EIE79932.1 - 0.0034 16.2 0.1 0.0051 15.6 0.1 1.3 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 TPR_14 PF13428.1 EIE79932.1 - 0.0078 16.7 1.0 0.5 11.1 0.1 3.1 1 1 2 3 3 3 1 Tetratricopeptide repeat CDC14 PF08045.6 EIE79932.1 - 0.018 14.1 0.2 0.026 13.6 0.1 1.2 1 0 0 1 1 1 0 Cell division control protein 14, SIN component eIF3_subunit PF08597.5 EIE79932.1 - 0.022 14.3 0.2 0.023 14.2 0.1 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit MutS_III PF05192.13 EIE79932.1 - 0.062 13.0 0.3 0.075 12.8 0.2 1.1 1 0 0 1 1 1 0 MutS domain III Alkyl_sulf_dimr PF14863.1 EIE79932.1 - 0.19 11.9 1.2 0.54 10.4 0.6 2.0 1 1 1 2 2 2 0 Alkyl sulfatase dimerisation TPR_7 PF13176.1 EIE79932.1 - 0.3 10.9 1.9 0.57 10.1 0.1 2.3 3 0 0 3 3 3 0 Tetratricopeptide repeat SH3_9 PF14604.1 EIE79933.1 - 3.8e-10 39.1 0.1 6.4e-10 38.4 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EIE79933.1 - 6.3e-07 28.7 0.1 1.2e-06 27.8 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EIE79933.1 - 1e-06 28.0 0.2 1.5e-06 27.4 0.2 1.3 1 0 0 1 1 1 1 SH3 domain WD40 PF00400.27 EIE79934.1 - 1.1e-64 212.1 13.9 3.4e-11 42.5 0.0 7.6 7 1 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EIE79934.1 - 3.9e-07 29.9 0.7 0.0012 18.6 0.0 3.2 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EIE79934.1 - 0.00014 20.1 6.4 0.33 9.0 1.1 4.4 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.9 EIE79934.1 - 0.00025 19.9 3.3 0.78 8.4 0.0 3.7 3 1 1 4 4 4 2 Coatomer WD associated region CLTH PF10607.4 EIE79934.1 - 0.0021 17.7 0.4 0.0044 16.7 0.3 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain PQQ_2 PF13360.1 EIE79934.1 - 0.033 13.6 1.0 1.1 8.6 0.7 2.7 1 1 0 1 1 1 0 PQQ-like domain LisH PF08513.6 EIE79934.1 - 0.14 11.9 0.2 0.56 10.0 0.1 2.1 2 0 0 2 2 2 0 LisH CAP_GLY PF01302.20 EIE79936.1 - 6.9e-22 76.9 0.3 1.1e-21 76.2 0.2 1.3 1 0 0 1 1 1 1 CAP-Gly domain BTB PF00651.26 EIE79936.1 - 3.7e-14 52.6 0.2 1.3e-11 44.4 0.1 2.5 2 0 0 2 2 2 2 BTB/POZ domain Methyltransf_11 PF08241.7 EIE79937.1 - 2.4e-09 37.5 0.0 3.9e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIE79937.1 - 1.9e-05 23.8 0.1 2.8e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EIE79937.1 - 0.00013 21.5 0.0 0.00025 20.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIE79937.1 - 0.0037 17.0 0.0 0.0048 16.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EIE79937.1 - 0.0047 16.5 0.0 0.0063 16.1 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_12 PF08242.7 EIE79937.1 - 0.0095 16.3 0.0 0.021 15.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIE79937.1 - 0.015 15.6 0.0 0.03 14.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain CDC45 PF02724.9 EIE79938.1 - 4.6e-22 77.8 0.0 5.2e-22 77.6 0.0 1.0 1 0 0 1 1 1 1 CDC45-like protein CBF PF03914.12 EIE79938.1 - 0.12 11.8 1.0 0.5 9.8 0.1 1.8 1 1 1 2 2 2 0 CBF/Mak21 family G-patch PF01585.18 EIE79939.1 - 1.2e-15 57.0 4.4 2.5e-15 55.9 3.0 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EIE79939.1 - 2.6e-09 36.7 0.4 2.6e-09 36.7 0.3 3.1 3 0 0 3 3 3 1 DExH-box splicing factor binding site OmpH PF03938.9 EIE79939.1 - 2.1 8.2 8.1 6 6.7 0.7 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF2407 PF10302.4 EIE79939.1 - 2.2 8.5 4.7 0.71 10.0 0.7 2.0 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain RNA_pol_Rpo13 PF12136.3 EIE79939.1 - 2.7 7.7 7.7 1 9.1 1.3 2.6 2 0 0 2 2 2 0 RNA polymerase Rpo13 subunit HTH domain Arginosuc_synth PF00764.14 EIE79940.1 - 2.1e-148 494.5 0.0 2.5e-148 494.2 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.8 EIE79940.1 - 0.0014 17.9 0.0 0.0022 17.2 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.11 EIE79940.1 - 0.039 12.4 0.0 0.056 11.9 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase Asn_synthase PF00733.16 EIE79940.1 - 0.072 12.5 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase DNA_pol_phi PF04931.8 EIE79941.1 - 4e-68 229.9 48.6 4.4e-67 226.5 33.7 2.5 1 1 0 1 1 1 1 DNA polymerase phi PC-Esterase PF13839.1 EIE79941.1 - 5e-12 46.2 0.7 3.6e-11 43.3 0.0 2.5 2 0 0 2 2 2 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Daxx PF03344.10 EIE79941.1 - 0.24 9.8 24.4 0.49 8.8 16.9 1.4 1 0 0 1 1 1 0 Daxx Family LacI PF00356.16 EIE79941.1 - 0.96 9.1 3.6 3.1 7.4 0.2 2.9 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family Nramp PF01566.13 EIE79942.1 - 5.7e-38 130.6 1.4 7e-38 130.3 1.0 1.0 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein RhoGEF PF00621.15 EIE79943.1 - 1.8e-27 96.3 2.1 1.8e-27 96.3 1.5 2.2 2 0 0 2 2 2 1 RhoGEF domain PH_5 PF15405.1 EIE79943.1 - 0.0092 15.9 1.8 0.019 14.9 0.0 2.5 3 0 0 3 3 3 1 Pleckstrin homology domain GRASP55_65 PF04495.9 EIE79944.1 - 1.7e-07 31.2 0.0 3.4e-07 30.3 0.0 1.5 1 1 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ_2 PF13180.1 EIE79944.1 - 0.026 14.4 0.0 0.052 13.4 0.0 1.5 1 0 0 1 1 1 0 PDZ domain DegS PF05384.6 EIE79944.1 - 0.04 13.1 0.4 7.8 5.6 0.0 2.2 2 0 0 2 2 2 0 Sensor protein DegS Nnf1 PF03980.9 EIE79944.1 - 0.089 12.7 0.8 0.16 12.0 0.6 1.4 1 0 0 1 1 1 0 Nnf1 DUF948 PF06103.6 EIE79944.1 - 0.23 11.3 3.4 0.46 10.3 0.3 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Zip PF02535.17 EIE79945.1 - 0.57 9.1 4.6 0.73 8.7 3.2 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Macoilin PF09726.4 EIE79945.1 - 1.3 7.1 6.3 1.5 7.0 4.4 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF1029 PF06269.7 EIE79946.1 - 0.049 13.6 0.5 0.064 13.2 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1029) FRG1 PF06229.7 EIE79948.1 - 0.055 12.9 0.0 0.058 12.8 0.0 1.1 1 0 0 1 1 1 0 FRG1-like family DDE_3 PF13358.1 EIE79949.1 - 8.3e-13 48.3 0.0 1.4e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE79950.1 - 5e-22 78.2 0.0 1e-21 77.2 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 EIE79950.1 - 0.0039 16.6 0.0 0.011 15.2 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.1 EIE79950.1 - 0.015 15.2 0.4 0.037 13.9 0.0 1.7 2 0 0 2 2 2 0 DDE domain RVT_1 PF00078.22 EIE79951.1 - 0.0021 17.4 0.0 0.0045 16.3 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.12 EIE79952.1 - 0.011 15.7 0.1 0.029 14.4 0.0 1.7 2 0 0 2 2 2 0 Retrotransposon gag protein Transposase_21 PF02992.9 EIE79953.1 - 1e-21 77.0 0.0 1.7e-21 76.4 0.0 1.2 1 0 0 1 1 1 1 Transposase family tnp2 DUF1258 PF06869.7 EIE79953.1 - 0.0028 16.7 0.4 0.006 15.6 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1258) LysR_substrate PF03466.15 EIE79953.1 - 0.17 10.9 0.0 0.3 10.1 0.0 1.3 1 0 0 1 1 1 0 LysR substrate binding domain FKBP_N PF01346.13 EIE79954.1 - 0.0049 16.8 0.9 0.0049 16.8 0.6 2.2 2 0 0 2 2 2 1 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase DUF947 PF06102.7 EIE79954.1 - 0.0065 16.3 0.8 0.095 12.5 0.0 2.7 3 1 0 3 3 3 1 Domain of unknown function (DUF947) LAG1-DNAbind PF09271.6 EIE79954.1 - 0.021 15.3 0.4 0.048 14.1 0.2 1.6 1 0 0 1 1 1 0 LAG1, DNA binding LexA_DNA_bind PF01726.11 EIE79954.1 - 0.061 12.8 0.0 0.18 11.4 0.0 1.7 1 0 0 1 1 1 0 LexA DNA binding domain YebO PF13974.1 EIE79954.1 - 0.089 12.5 7.9 0.84 9.4 0.0 2.4 2 0 0 2 2 2 0 YebO-like protein HTH_37 PF13744.1 EIE79954.1 - 0.76 9.6 7.3 14 5.5 4.1 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain DDE_3 PF13358.1 EIE79956.1 - 5.3e-16 58.6 0.0 7.6e-16 58.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease FlpD PF02662.11 EIE79956.1 - 0.16 11.6 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 Methyl-viologen-reducing hydrogenase, delta subunit UBN2_2 PF14227.1 EIE79957.1 - 0.014 14.9 0.2 0.51 9.9 0.0 3.0 3 0 0 3 3 3 0 gag-polypeptide of LTR copia-type DUF3019 PF11456.3 EIE79958.1 - 0.049 13.9 0.1 0.049 13.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3019) HTH_Tnp_Tc3_2 PF01498.13 EIE79959.1 - 2.8e-09 36.9 2.6 5.6e-08 32.7 0.9 2.7 3 0 0 3 3 3 1 Transposase DDE_3 PF13358.1 EIE79959.1 - 2.7e-08 33.6 0.0 7.2e-08 32.3 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_23 PF13384.1 EIE79959.1 - 6.5e-05 22.4 0.0 0.00053 19.5 0.0 2.4 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.1 EIE79959.1 - 0.012 15.6 0.2 0.23 11.5 0.0 2.6 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_29 PF13551.1 EIE79959.1 - 0.02 15.0 0.3 0.11 12.6 0.0 2.2 1 1 1 2 2 2 0 Winged helix-turn helix HTH_Tnp_ISL3 PF13542.1 EIE79959.1 - 0.025 13.7 0.0 0.47 9.6 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 Sigma70_r4_2 PF08281.7 EIE79959.1 - 0.047 13.1 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_17 PF12728.2 EIE79959.1 - 0.07 13.3 0.1 0.23 11.7 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain GerE PF00196.14 EIE79959.1 - 0.085 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family HTH_Tnp_Tc3_2 PF01498.13 EIE79961.1 - 4.4e-08 33.0 0.6 1.6e-07 31.2 0.1 2.1 2 1 1 3 3 3 1 Transposase HTH_Tnp_ISL3 PF13542.1 EIE79962.1 - 7.7e-05 21.7 0.3 9.5e-05 21.4 0.2 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_23 PF13384.1 EIE79962.1 - 0.0029 17.1 0.0 0.0033 17.0 0.0 1.1 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.1 EIE79962.1 - 0.0094 15.9 0.0 0.013 15.5 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_11 PF08279.7 EIE79962.1 - 0.021 14.4 0.1 0.024 14.2 0.0 1.2 1 0 0 1 1 1 0 HTH domain HTH_DeoR PF08220.7 EIE79962.1 - 0.061 12.8 0.1 0.075 12.5 0.1 1.2 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain MerR PF00376.18 EIE79962.1 - 0.064 12.8 0.1 0.1 12.1 0.1 1.3 1 0 0 1 1 1 0 MerR family regulatory protein Sigma70_r4_2 PF08281.7 EIE79962.1 - 0.11 11.9 0.1 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Sigma-70, region 4 DDE_3 PF13358.1 EIE79963.1 - 3.2e-19 69.1 1.3 3.7e-19 68.9 0.3 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_38 PF13936.1 EIE79963.1 - 0.00017 21.0 0.4 0.00034 20.1 0.1 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.1 EIE79963.1 - 0.0063 16.1 0.1 0.0063 16.1 0.1 1.7 2 0 0 2 2 2 1 Homeodomain-like domain MarR PF01047.17 EIE79963.1 - 0.024 14.3 0.0 0.12 12.0 0.0 2.0 2 0 0 2 2 2 0 MarR family Fe_dep_repress PF01325.14 EIE79963.1 - 0.058 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain Sigma54_DBD PF04552.8 EIE79963.1 - 0.082 12.4 0.1 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Sigma-54, DNA binding domain HTH_Crp_2 PF13545.1 EIE79963.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain TrmB PF01978.14 EIE79963.1 - 0.13 12.0 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_30 PF13556.1 EIE79964.1 - 0.014 14.9 0.0 0.031 13.8 0.0 1.6 1 1 1 2 2 2 0 PucR C-terminal helix-turn-helix domain MULE PF10551.4 EIE79965.1 - 2.7e-07 30.6 0.2 8.3e-07 29.0 0.0 1.8 1 1 1 2 2 2 1 MULE transposase domain DDE_3 PF13358.1 EIE79966.1 - 5.6e-11 42.3 0.8 2.7e-10 40.1 0.2 2.1 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE79966.1 - 2.3e-08 33.9 3.3 2.8e-08 33.7 0.2 2.3 1 1 1 2 2 2 1 Transposase HTH_29 PF13551.1 EIE79966.1 - 0.001 19.2 1.7 0.0028 17.7 1.2 1.8 1 1 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_ISL3 PF13542.1 EIE79966.1 - 0.033 13.3 0.6 0.033 13.3 0.4 2.5 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 HTH_12 PF08461.5 EIE79966.1 - 0.087 12.5 0.1 0.31 10.7 0.0 1.9 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain HTH_32 PF13565.1 EIE79966.1 - 0.29 11.9 4.2 0.22 12.3 0.5 2.6 4 0 0 4 4 3 0 Homeodomain-like domain HTH_23 PF13384.1 EIE79966.1 - 0.31 10.7 2.9 3.2 7.5 0.2 2.6 2 0 0 2 2 2 0 Homeodomain-like domain HTH_21 PF13276.1 EIE79966.1 - 0.46 10.5 3.7 1.1 9.2 0.0 2.7 3 0 0 3 3 3 0 HTH-like domain DUF1033 PF06279.6 EIE79966.1 - 0.5 10.2 4.7 0.52 10.1 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1033) NFRKB_winged PF14465.1 EIE79966.1 - 0.88 9.4 5.3 2.4 8.0 0.5 2.8 2 2 0 2 2 2 0 NFRKB Winged Helix-like ELL PF10390.4 EIE79966.1 - 4.3 6.4 6.6 0.41 9.8 0.6 2.1 2 0 0 2 2 2 0 RNA polymerase II elongation factor ELL DUF919 PF06034.6 EIE79967.1 - 0.23 11.1 2.7 11 5.7 0.1 2.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) DDE_3 PF13358.1 EIE79969.1 - 9.5e-16 57.8 0.1 1.8e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE79969.1 - 2.5e-10 40.2 0.5 8e-10 38.6 0.2 2.0 2 0 0 2 2 2 1 Transposase Transposase_21 PF02992.9 EIE79970.1 - 1.4e-07 30.8 0.0 1.7e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Transposase family tnp2 DDE_Tnp_IS1595 PF12762.2 EIE79971.1 - 1.4e-22 80.1 0.5 2.3e-22 79.4 0.4 1.3 1 0 0 1 1 1 1 ISXO2-like transposase domain HTH_Tnp_Tc3_2 PF01498.13 EIE79972.1 - 6.5e-07 29.3 0.1 8.6e-07 28.9 0.1 1.2 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.1 EIE79973.1 - 7.1e-12 45.2 0.2 1e-11 44.8 0.2 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4218 PF13960.1 EIE79976.1 - 0.03 13.7 0.2 0.07 12.5 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) HTH_Tnp_Tc3_2 PF01498.13 EIE79977.1 - 2.5e-12 46.6 1.0 2.5e-12 46.6 0.7 1.9 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 EIE79977.1 - 7.3e-05 22.8 0.8 0.00017 21.6 0.1 1.8 2 0 0 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.1 EIE79977.1 - 0.00048 19.6 0.1 0.0013 18.2 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_7 PF02796.10 EIE79977.1 - 0.0039 17.0 0.0 0.011 15.5 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase DDE_3 PF13358.1 EIE79977.1 - 0.0059 16.3 0.0 0.015 15.0 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.1 EIE79977.1 - 0.017 14.6 0.0 0.061 12.8 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_30 PF13556.1 EIE79977.1 - 0.055 13.0 0.0 0.098 12.2 0.0 1.3 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain RecX PF02631.11 EIE79977.1 - 0.059 13.5 0.3 0.12 12.6 0.2 1.5 1 0 0 1 1 1 0 RecX family HTH_32 PF13565.1 EIE79977.1 - 0.45 11.3 3.9 0.67 10.7 0.2 2.6 2 1 1 3 3 3 0 Homeodomain-like domain Transposase_21 PF02992.9 EIE79978.1 - 6.1e-22 77.8 0.0 1.3e-21 76.7 0.0 1.5 1 0 0 1 1 1 1 Transposase family tnp2 DUF1258 PF06869.7 EIE79978.1 - 0.0024 17.0 0.0 0.0038 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) RVT_1 PF00078.22 EIE79980.1 - 4.5e-19 68.6 0.2 1.9e-09 37.1 0.0 2.5 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease PF09668.5 EIE79980.1 - 6.1e-09 35.5 0.0 1.3e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 EIE79980.1 - 5.7e-07 29.9 0.0 1.3e-06 28.7 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 EIE79980.1 - 3.1e-05 23.8 0.0 0.00013 21.8 0.0 2.1 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.6 EIE79980.1 - 0.0016 18.3 0.0 0.0035 17.2 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.12 EIE79980.1 - 0.0044 17.0 0.1 0.022 14.8 0.0 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein gag-asp_proteas PF13975.1 EIE79980.1 - 0.02 14.7 0.0 0.041 13.7 0.0 1.4 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DDE_3 PF13358.1 EIE79985.1 - 1e-20 73.9 0.4 1.9e-20 73.0 0.1 1.5 2 0 0 2 2 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE79985.1 - 1.8e-16 59.9 3.5 2e-16 59.7 0.4 2.3 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 EIE79985.1 - 2.4e-09 37.3 0.3 9e-09 35.4 0.1 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.1 EIE79985.1 - 3.6e-09 35.9 0.1 2.2e-06 27.1 0.0 3.0 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.1 EIE79985.1 - 9.3e-08 32.7 0.8 1.1e-05 26.1 0.0 3.8 3 1 1 4 4 4 1 Homeodomain-like domain HTH_36 PF13730.1 EIE79985.1 - 2.7e-06 27.4 2.0 0.00027 21.0 0.3 3.6 3 1 1 4 4 3 1 Helix-turn-helix domain HTH_7 PF02796.10 EIE79985.1 - 3.8e-06 26.6 4.4 0.00025 20.8 0.4 3.3 2 1 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_11 PF08279.7 EIE79985.1 - 3.8e-06 26.4 1.9 0.00034 20.1 0.2 2.6 2 0 0 2 2 2 1 HTH domain HTH_21 PF13276.1 EIE79985.1 - 8.6e-06 25.6 0.1 0.00021 21.2 0.0 2.9 3 0 0 3 3 3 1 HTH-like domain HTH_28 PF13518.1 EIE79985.1 - 1.4e-05 24.9 0.0 0.0061 16.5 0.0 2.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_38 PF13936.1 EIE79985.1 - 2.3e-05 23.8 0.8 0.00013 21.3 0.1 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_33 PF13592.1 EIE79985.1 - 0.00013 21.3 0.1 0.00054 19.4 0.0 2.1 2 0 0 2 2 1 1 Winged helix-turn helix HTH_24 PF13412.1 EIE79985.1 - 0.00015 21.0 0.5 0.014 14.8 0.1 3.0 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_Tnp_ISL3 PF13542.1 EIE79985.1 - 0.00045 19.3 0.1 0.1 11.7 0.0 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 GerE PF00196.14 EIE79985.1 - 0.00093 18.4 0.2 0.0026 17.0 0.1 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family KorB PF08535.5 EIE79985.1 - 0.0018 18.4 0.1 0.0045 17.1 0.0 1.6 1 0 0 1 1 1 1 KorB domain HTH_3 PF01381.17 EIE79985.1 - 0.002 17.9 1.2 0.029 14.2 0.3 2.3 2 0 0 2 2 2 1 Helix-turn-helix GntR PF00392.16 EIE79985.1 - 0.0025 17.1 0.1 0.54 9.7 0.0 2.6 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family TrmB PF01978.14 EIE79985.1 - 0.0026 17.4 0.6 0.033 13.8 0.1 2.5 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB Sigma70_r4_2 PF08281.7 EIE79985.1 - 0.0026 17.1 0.3 0.021 14.2 0.1 2.3 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_AsnC-type PF13404.1 EIE79985.1 - 0.0027 17.2 0.1 0.0084 15.6 0.0 1.8 2 0 0 2 2 1 1 AsnC-type helix-turn-helix domain Phage_terminase PF10668.4 EIE79985.1 - 0.0028 17.3 0.1 0.0028 17.3 0.1 2.5 3 0 0 3 3 2 1 Phage terminase small subunit LacI PF00356.16 EIE79985.1 - 0.0035 16.9 0.3 1.5 8.5 0.1 2.5 2 0 0 2 2 2 1 Bacterial regulatory proteins, lacI family HTH_17 PF12728.2 EIE79985.1 - 0.0045 17.2 0.2 1.5 9.1 0.0 3.7 4 0 0 4 4 3 1 Helix-turn-helix domain HTH_10 PF04967.7 EIE79985.1 - 0.013 15.0 0.1 0.41 10.2 0.0 2.5 2 0 0 2 2 2 0 HTH DNA binding domain HTH_Tnp_1_2 PF13022.1 EIE79985.1 - 0.015 15.1 0.1 0.37 10.5 0.0 2.7 3 0 0 3 3 3 0 Helix-turn-helix of insertion element transposase HTH_5 PF01022.15 EIE79985.1 - 0.017 14.8 0.0 0.2 11.3 0.0 2.3 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family Trp_repressor PF01371.14 EIE79985.1 - 0.017 14.9 0.6 0.066 13.1 0.1 2.1 2 0 0 2 2 2 0 Trp repressor protein Sigma54_DBD PF04552.8 EIE79985.1 - 0.025 14.0 0.4 0.32 10.5 0.1 2.6 2 0 0 2 2 2 0 Sigma-54, DNA binding domain CENP-B_N PF04218.8 EIE79985.1 - 0.029 13.7 0.1 0.67 9.4 0.1 2.4 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain HTH_IclR PF09339.5 EIE79985.1 - 0.038 13.5 0.4 0.21 11.1 0.0 2.4 4 0 0 4 4 2 0 IclR helix-turn-helix domain HTH_6 PF01418.12 EIE79985.1 - 0.048 13.4 0.8 3.4 7.4 0.1 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family HMG_box_2 PF09011.5 EIE79985.1 - 0.051 13.9 2.1 0.14 12.5 0.3 2.3 2 0 0 2 2 2 0 HMG-box domain rve PF00665.21 EIE79985.1 - 0.063 13.3 0.0 0.21 11.6 0.0 2.1 1 1 0 1 1 1 0 Integrase core domain HTH_22 PF13309.1 EIE79985.1 - 0.079 12.7 0.1 0.55 10.0 0.0 2.3 2 0 0 2 2 2 0 HTH domain DDE_Tnp_IS66 PF03050.9 EIE79985.1 - 0.2 10.8 3.5 4.3 6.4 0.1 3.0 3 0 0 3 3 3 0 Transposase IS66 family HMG_box PF00505.14 EIE79985.1 - 0.25 11.6 4.4 0.54 10.5 0.6 3.0 3 0 0 3 3 3 0 HMG (high mobility group) box Fe_dep_repress PF01325.14 EIE79985.1 - 0.29 11.0 1.7 3.6 7.5 0.1 3.0 3 0 0 3 3 3 0 Iron dependent repressor, N-terminal DNA binding domain DDE_3 PF13358.1 EIE79987.1 - 3.6e-13 49.5 0.2 4.9e-13 49.0 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE79987.1 - 0.017 15.2 0.0 0.025 14.6 0.0 1.3 1 0 0 1 1 1 0 Integrase core domain DDE_3 PF13358.1 EIE79989.1 - 2.5e-18 66.2 0.0 3.4e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE79989.1 - 0.033 14.3 0.0 0.069 13.2 0.0 1.6 1 1 0 1 1 1 0 Integrase core domain HMG_box PF00505.14 EIE79989.1 - 0.11 12.7 0.7 0.18 12.0 0.2 1.7 2 0 0 2 2 2 0 HMG (high mobility group) box DDE_3 PF13358.1 EIE79990.1 - 4.7e-15 55.6 0.0 7.1e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE79990.1 - 2.7e-11 43.3 0.3 5.2e-11 42.4 0.2 1.5 1 0 0 1 1 1 1 Transposase DUF805 PF05656.9 EIE79991.1 - 0.041 13.7 0.0 0.041 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF805) DDE_Tnp_IS1595 PF12762.2 EIE79994.1 - 2.9e-06 27.2 0.1 5.3e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 ISXO2-like transposase domain E1-E2_ATPase PF00122.15 EIE79996.1 - 3.1e-77 258.7 1.4 3.1e-77 258.7 1.0 2.2 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EIE79996.1 - 3e-44 150.7 4.9 3e-44 150.7 3.4 2.3 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EIE79996.1 - 6.4e-34 118.2 0.0 1.9e-33 116.7 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EIE79996.1 - 5.2e-19 67.9 0.0 1.3e-18 66.7 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EIE79996.1 - 4.5e-17 61.2 0.0 9.9e-17 60.1 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EIE79996.1 - 6.8e-16 58.9 0.0 2e-15 57.4 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EIE79996.1 - 1.5e-05 24.6 3.6 0.0012 18.5 1.1 2.7 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EIE79996.1 - 0.0032 17.7 0.0 0.0088 16.2 0.0 1.7 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HTH_22 PF13309.1 EIE79996.1 - 0.027 14.2 0.1 0.68 9.7 0.0 3.1 3 0 0 3 3 3 0 HTH domain Hydrolase_6 PF13344.1 EIE79996.1 - 0.034 14.0 0.0 0.099 12.5 0.0 1.8 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DUF1794 PF08768.6 EIE79996.1 - 0.035 13.9 0.1 1.7 8.5 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1794) CBS PF00571.23 EIE79997.1 - 6.3e-14 51.4 0.0 6.6e-06 25.8 0.1 3.7 3 0 0 3 3 3 3 CBS domain Chitin_synth_2 PF03142.10 EIE79998.1 - 3.6e-231 768.1 1.0 5.5e-231 767.5 0.7 1.2 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 EIE79998.1 - 2.5e-18 66.4 4.9 2.5e-18 66.4 3.4 2.2 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EIE79998.1 - 9.2e-15 55.0 0.1 5.5e-14 52.5 0.1 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EIE79998.1 - 6.6e-06 25.5 0.5 0.00018 20.8 0.1 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EIE79998.1 - 0.00057 19.5 0.0 0.01 15.5 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 Cyt-b5 PF00173.23 EIE79998.1 - 0.0014 18.4 0.0 0.0028 17.4 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Pox_A14 PF05767.7 EIE79998.1 - 1.8 8.5 9.3 0.25 11.3 0.1 2.7 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 HMG_box PF00505.14 EIE79999.1 - 1.7e-25 89.0 6.4 3.1e-25 88.2 4.5 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EIE79999.1 - 3.2e-17 62.6 6.5 5.2e-17 61.9 4.5 1.4 1 0 0 1 1 1 1 HMG-box domain CHDNT PF08073.7 EIE79999.1 - 0.00011 21.7 0.4 0.00018 21.1 0.0 1.5 2 0 0 2 2 2 1 CHDNT (NUC034) domain HMG_box_5 PF14887.1 EIE79999.1 - 0.0053 16.5 6.7 0.0053 16.5 4.7 1.9 1 1 0 1 1 1 1 HMG (high mobility group) box 5 DUF1289 PF06945.8 EIE79999.1 - 0.16 11.4 0.5 0.65 9.5 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1289) Ribosomal_S25 PF03297.10 EIE79999.1 - 9.9 6.2 10.8 0.087 12.8 0.9 1.9 2 0 0 2 2 2 0 S25 ribosomal protein ECM1 PF05782.6 EIE80000.1 - 0.039 12.6 3.0 0.042 12.5 2.0 1.1 1 0 0 1 1 1 0 Extracellular matrix protein 1 (ECM1) DUF3746 PF12562.3 EIE80001.1 - 0.075 12.8 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3746) MFS_1 PF07690.11 EIE80002.1 - 2.4e-21 75.8 22.8 2.4e-21 75.8 15.8 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Adeno_E3_14_5 PF04834.7 EIE80002.1 - 0.17 12.3 3.9 0.14 12.6 0.3 2.5 1 1 1 2 2 2 0 Early E3 14.5 kDa protein SDA1 PF05285.7 EIE80003.1 - 0.078 12.2 34.0 0.11 11.7 23.6 1.2 1 0 0 1 1 1 0 SDA1 PLRV_ORF5 PF01690.12 EIE80003.1 - 3.9 6.5 20.9 4.9 6.1 14.5 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF966 PF06136.8 EIE80003.1 - 4.5 6.6 19.5 5.6 6.2 13.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) SpoU_sub_bind PF08032.7 EIE80004.1 - 0.0052 16.9 0.2 0.0068 16.5 0.1 1.3 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding Sec23_helical PF04815.10 EIE80004.1 - 0.037 13.4 0.3 0.079 12.3 0.1 1.6 1 1 1 2 2 2 0 Sec23/Sec24 helical domain C4 PF01413.14 EIE80004.1 - 0.062 13.2 0.0 0.079 12.8 0.0 1.2 1 0 0 1 1 1 0 C-terminal tandem repeated domain in type 4 procollagen WD40 PF00400.27 EIE80005.1 - 1.6e-64 211.6 18.6 2.6e-12 46.1 0.0 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat TFIID_90kDa PF04494.10 EIE80005.1 - 1.5e-44 151.4 3.6 4.7e-44 149.9 2.0 2.2 2 0 0 2 2 2 1 WD40 associated region in TFIID subunit Nup160 PF11715.3 EIE80005.1 - 1.7e-07 29.7 0.4 0.06 11.4 0.0 3.5 2 1 1 3 3 3 3 Nucleoporin Nup120/160 eIF2A PF08662.6 EIE80005.1 - 0.012 15.3 0.1 0.2 11.3 0.0 2.7 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 EIE80005.1 - 0.022 13.5 0.1 5.5 5.6 0.0 3.3 2 1 2 4 4 4 0 Nup133 N terminal like LisH PF08513.6 EIE80005.1 - 0.1 12.3 0.5 0.46 10.3 0.0 2.4 2 0 0 2 2 2 0 LisH Cytochrom_D1 PF02239.11 EIE80005.1 - 0.13 10.4 0.0 0.27 9.4 0.0 1.4 2 0 0 2 2 2 0 Cytochrome D1 heme domain Cnd1_N PF12922.2 EIE80006.1 - 1.2e-40 138.9 0.7 2.2e-40 138.0 0.5 1.5 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1, N-term zf-C2H2_2 PF12756.2 EIE80006.1 - 9.8e-33 112.2 8.2 2.6e-26 91.6 0.1 3.7 2 2 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 EIE80006.1 - 7.4e-10 38.6 14.3 4.4e-07 29.8 2.7 3.7 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EIE80006.1 - 9.2e-08 32.0 9.4 4.9e-07 29.7 2.9 2.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type AKAP95 PF04988.7 EIE80006.1 - 0.00075 19.3 5.2 0.4 10.4 0.9 2.8 2 0 0 2 2 2 2 A-kinase anchoring protein 95 (AKAP95) P63C PF10546.4 EIE80006.1 - 0.0098 15.8 0.1 0.027 14.4 0.0 1.8 1 0 0 1 1 1 1 P63C domain zf-C2H2_6 PF13912.1 EIE80006.1 - 0.055 13.3 9.6 0.06 13.2 0.4 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_4 PF13894.1 EIE80006.1 - 0.23 11.8 12.1 0.17 12.2 0.7 3.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EIE80006.1 - 0.59 10.5 3.4 3.8 7.9 0.0 3.7 3 0 0 3 3 3 0 Zinc-finger double domain Cnd1 PF12717.2 EIE80007.1 - 4.1e-57 192.8 1.5 9.3e-57 191.7 1.0 1.7 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.15 EIE80007.1 - 0.0016 16.9 9.4 0.012 13.9 0.4 3.4 2 2 1 3 3 3 2 Adaptin N terminal region HEAT_2 PF13646.1 EIE80007.1 - 0.0051 17.0 0.6 0.14 12.4 0.0 3.5 4 0 0 4 4 4 1 HEAT repeats HEAT_EZ PF13513.1 EIE80007.1 - 0.048 14.1 0.0 8 7.0 0.0 3.3 3 0 0 3 3 3 0 HEAT-like repeat HEAT PF02985.17 EIE80007.1 - 0.17 12.0 0.2 12 6.3 0.0 3.8 4 0 0 4 4 4 0 HEAT repeat Nop14 PF04147.7 EIE80007.1 - 7.3 4.3 56.9 0.037 11.9 4.6 2.7 2 0 0 2 2 2 0 Nop14-like family Asp PF00026.18 EIE80008.1 - 3.2e-48 164.6 0.4 3.9e-48 164.3 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIE80008.1 - 1.4e-07 31.6 0.1 1.2e-06 28.5 0.0 2.4 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EIE80008.1 - 0.00056 20.3 1.3 0.15 12.5 0.1 3.3 2 1 0 2 2 2 2 Aspartyl protease PH PF00169.24 EIE80009.1 - 2.4e-20 72.6 1.3 8.4e-20 70.9 0.9 1.9 1 0 0 1 1 1 1 PH domain SAM_2 PF07647.12 EIE80009.1 - 1.8e-17 62.9 0.1 3.2e-17 62.1 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.1 EIE80009.1 - 2.3e-14 52.7 0.1 5.4e-14 51.4 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SAM_1 PF00536.25 EIE80009.1 - 6.5e-14 51.8 0.1 1.4e-13 50.7 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_1 PF00018.23 EIE80009.1 - 1.7e-12 46.4 0.2 6e-12 44.7 0.2 2.0 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EIE80009.1 - 5.6e-10 38.5 0.1 1.3e-09 37.3 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain PH_11 PF15413.1 EIE80009.1 - 4.7e-07 30.0 3.4 9.3e-06 25.8 2.4 2.7 1 1 0 1 1 1 1 Pleckstrin homology domain CH PF00307.26 EIE80009.1 - 2.4e-06 27.5 0.0 6.5e-06 26.1 0.0 1.8 2 0 0 2 2 2 1 Calponin homology (CH) domain PH_8 PF15409.1 EIE80009.1 - 0.00094 19.2 0.6 0.0029 17.6 0.4 1.9 1 1 0 1 1 1 1 Pleckstrin homology domain Ste50p-SAM PF09235.5 EIE80009.1 - 0.027 14.4 0.1 0.064 13.2 0.1 1.7 1 0 0 1 1 1 0 Ste50p, sterile alpha motif SAM_PNT PF02198.11 EIE80009.1 - 0.067 12.9 0.7 0.42 10.3 0.0 2.3 2 0 0 2 2 2 0 Sterile alpha motif (SAM)/Pointed domain PH_3 PF14593.1 EIE80009.1 - 0.073 12.9 0.7 0.18 11.7 0.5 1.6 1 0 0 1 1 1 0 PH domain Cyclin PF08613.6 EIE80011.1 - 9e-20 71.6 0.8 1.3e-19 71.0 0.1 1.5 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 EIE80011.1 - 0.0013 18.3 0.1 0.0024 17.4 0.0 1.5 2 0 0 2 2 2 1 Cyclin, N-terminal domain Mg_trans_NIPA PF05653.9 EIE80013.1 - 1.2e-15 57.3 14.7 3.7e-15 55.6 10.2 1.7 1 1 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 EIE80013.1 - 0.00021 21.4 5.6 0.00021 21.4 3.9 2.8 2 1 0 2 2 2 2 Multidrug resistance efflux transporter EamA PF00892.15 EIE80013.1 - 0.0016 18.4 4.5 0.0016 18.4 3.1 2.8 3 0 0 3 3 3 2 EamA-like transporter family DUF3520 PF12034.3 EIE80014.1 - 0.025 14.7 1.4 0.035 14.2 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3520) DUF3530 PF12048.3 EIE80015.1 - 0.087 11.7 0.1 0.12 11.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Xan_ur_permease PF00860.15 EIE80016.1 - 0.028 12.9 0.8 0.03 12.8 0.6 1.0 1 0 0 1 1 1 0 Permease family Claudin_2 PF13903.1 EIE80016.1 - 0.063 12.9 1.5 0.071 12.8 1.0 1.1 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Phosphorylase PF00343.15 EIE80018.1 - 0 1051.7 0.5 0 1051.5 0.3 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase DEAD PF00270.24 EIE80019.1 - 4.5e-46 156.4 0.9 1.7e-45 154.5 0.0 2.2 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIE80019.1 - 1.5e-27 95.2 0.0 8.9e-27 92.7 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIE80019.1 - 0.00019 21.3 0.0 0.001 18.9 0.0 2.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Cyclin PF08613.6 EIE80020.1 - 1.4e-13 51.4 0.1 1.6e-13 51.3 0.1 1.1 1 0 0 1 1 1 1 Cyclin DUF4625 PF15418.1 EIE80021.1 - 0.056 13.5 0.0 0.081 13.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4625) NPCBM_assoc PF10633.4 EIE80021.1 - 0.074 13.1 0.2 2.8 8.0 0.1 2.5 2 1 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase E1_DerP2_DerF2 PF02221.10 EIE80021.1 - 0.083 13.1 0.3 0.14 12.3 0.2 1.6 1 1 0 1 1 1 0 ML domain ADH_zinc_N PF00107.21 EIE80022.1 - 3.4e-26 91.3 0.0 5.4e-26 90.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIE80022.1 - 3.4e-14 53.8 0.0 1.5e-13 51.7 0.0 2.0 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIE80022.1 - 0.0017 18.0 3.1 0.0018 18.0 0.3 2.3 2 2 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain HupF_HypC PF01455.13 EIE80022.1 - 0.0052 16.7 0.2 4.6 7.3 0.0 2.8 1 1 1 2 2 2 2 HupF/HypC family Cpn10 PF00166.16 EIE80022.1 - 0.0064 16.4 2.3 0.033 14.1 0.6 2.5 2 1 0 2 2 2 1 Chaperonin 10 Kd subunit YbgT_YccB PF08173.6 EIE80024.1 - 1.5 8.6 12.1 5 7.0 1.8 3.0 2 0 0 2 2 2 0 Membrane bound YbgT-like protein Na_Ca_ex PF01699.19 EIE80025.1 - 4.7e-20 71.6 14.3 4.7e-20 71.6 9.9 2.2 3 0 0 3 3 3 1 Sodium/calcium exchanger protein DUF3487 PF11990.3 EIE80025.1 - 3.7 6.9 8.0 0.15 11.4 0.1 2.5 1 1 1 3 3 3 0 Protein of unknown function (DUF3487) Glyco_hydro_28 PF00295.12 EIE80026.1 - 6.4e-65 219.2 25.0 8.2e-65 218.8 17.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pkinase PF00069.20 EIE80027.1 - 2.2e-44 151.5 0.0 2.6e-44 151.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE80027.1 - 9.6e-25 87.1 0.0 1.2e-24 86.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE80027.1 - 0.0001 21.4 0.0 0.00014 20.9 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EIE80027.1 - 0.0001 21.4 0.1 0.00017 20.7 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family HAD PF12710.2 EIE80028.1 - 1.5e-14 54.6 0.0 3e-13 50.3 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EIE80028.1 - 5.2e-13 49.8 0.1 2.2e-09 38.0 0.2 3.5 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EIE80028.1 - 6.5e-12 45.2 0.0 2.1e-11 43.6 0.0 1.8 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit E1-E2_ATPase PF00122.15 EIE80028.1 - 6.7e-12 44.9 0.0 6.7e-12 44.9 0.0 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.7 EIE80028.1 - 0.0028 17.2 0.1 0.012 15.1 0.1 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF4392 PF14336.1 EIE80028.1 - 0.06 12.1 0.3 0.18 10.5 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4392) UPF0542 PF15086.1 EIE80028.1 - 0.29 10.8 3.4 0.37 10.5 0.2 2.6 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 Polysacc_deac_1 PF01522.16 EIE80029.1 - 2.2e-12 46.7 0.2 1.2e-11 44.3 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide deacetylase Mucin PF01456.12 EIE80029.1 - 5.1 6.8 17.1 0.91 9.2 6.3 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF2408 PF10303.4 EIE80030.1 - 2.9e-05 24.1 0.9 0.00013 22.0 0.6 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2408) CZB PF13682.1 EIE80030.1 - 0.0038 17.3 0.3 0.28 11.4 0.1 2.2 2 0 0 2 2 2 1 Chemoreceptor zinc-binding domain DUF2524 PF10732.4 EIE80030.1 - 0.03 14.4 1.3 0.086 12.9 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2524) Plasmid_killer PF05015.8 EIE80030.1 - 0.078 13.1 0.1 0.11 12.6 0.1 1.4 1 1 0 1 1 1 0 Plasmid maintenance system killer protein DUF1139 PF06599.6 EIE80030.1 - 0.11 11.6 0.1 0.12 11.5 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1139) Ribosomal_S2 PF00318.15 EIE80031.1 - 8e-43 146.1 0.0 7.3e-21 74.3 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 HLH PF00010.21 EIE80032.1 - 3.3e-13 49.0 1.6 7.1e-13 48.0 1.1 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain FAM101 PF15068.1 EIE80032.1 - 0.62 9.4 10.4 0.087 12.2 3.4 2.1 1 1 1 2 2 2 0 FAM101 family Ribosomal_L34e PF01199.13 EIE80032.1 - 7.5 6.8 10.1 4.9 7.4 3.9 2.3 2 0 0 2 2 2 0 Ribosomal protein L34e DUF2422 PF10337.4 EIE80032.1 - 9.1 4.9 10.8 13 4.4 7.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) Polysacc_deac_1 PF01522.16 EIE80033.1 - 1e-29 102.6 0.0 1.6e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 EIE80033.1 - 2.3e-06 26.7 0.1 2.9e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 DUF2334 PF10096.4 EIE80033.1 - 0.01 15.2 0.7 0.018 14.4 0.5 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) Polysacc_deac_1 PF01522.16 EIE80034.1 - 3e-27 94.7 0.0 4.6e-27 94.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 EIE80034.1 - 4.7e-06 25.7 0.0 8.6e-06 24.8 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 57 Polysacc_deac_1 PF01522.16 EIE80035.1 - 2.1e-26 91.9 0.0 3.2e-26 91.3 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 EIE80035.1 - 2.9e-06 26.4 0.1 5.3e-06 25.5 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 57 Polysacc_deac_1 PF01522.16 EIE80039.1 - 2e-27 95.2 0.0 3e-27 94.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 EIE80039.1 - 5e-06 25.6 0.0 1.1e-05 24.5 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 57 Phage_connect_1 PF05135.8 EIE80039.1 - 0.019 15.1 0.4 11 6.2 0.0 2.7 2 1 0 2 2 2 0 Phage gp6-like head-tail connector protein Arrestin_C PF02752.17 EIE80040.1 - 2.6e-14 53.4 0.1 1.9e-12 47.4 0.1 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EIE80040.1 - 1.6e-05 24.7 0.0 0.076 12.8 0.0 3.7 2 2 2 4 4 4 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 EIE80040.1 - 9.9e-05 21.9 0.0 0.00042 19.8 0.0 1.9 1 1 0 1 1 1 1 Arrestin_N terminal like Lir1 PF07207.6 EIE80041.1 - 0.14 12.4 0.0 0.15 12.2 0.0 1.1 1 0 0 1 1 1 0 Light regulated protein Lir1 HARE-HTH PF05066.8 EIE80042.1 - 0.0012 19.1 0.0 0.0037 17.5 0.0 1.8 1 0 0 1 1 1 1 HB1, ASXL, restriction endonuclease HTH domain Apt1 PF10351.4 EIE80043.1 - 2.1e-107 359.8 3.1 2.1e-107 359.8 2.1 2.4 2 0 0 2 2 2 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.4 EIE80043.1 - 3.3e-79 266.5 15.1 3.3e-79 266.5 10.5 1.9 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.4 EIE80043.1 - 4.4e-39 133.9 0.0 1.6e-38 132.1 0.0 2.0 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 EIE80043.1 - 1.8e-23 83.0 0.5 1.7e-22 79.8 0.0 2.7 1 1 1 2 2 2 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.4 EIE80043.1 - 2.6e-16 59.9 1.8 2.1e-14 53.7 0.2 4.1 2 1 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain DUF4124 PF13511.1 EIE80045.1 - 0.24 11.4 1.7 0.3 11.1 0.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4124) KH_1 PF00013.24 EIE80046.1 - 1.3e-43 146.4 6.4 3e-15 55.5 0.2 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EIE80046.1 - 1.6e-33 113.7 7.6 3.1e-11 42.6 0.2 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 EIE80046.1 - 1.1e-12 47.3 3.4 0.00075 19.0 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 EIE80046.1 - 1.2e-06 28.0 6.6 0.091 12.4 0.1 3.9 4 0 0 4 4 4 3 KH domain Fer2_3 PF13085.1 EIE80047.1 - 1.2e-27 95.9 0.0 2.7e-27 94.7 0.0 1.6 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain HisKA PF00512.20 EIE80047.1 - 5e-21 74.4 0.3 2.3e-20 72.3 0.1 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.6 EIE80047.1 - 6.4e-21 74.2 0.0 6.3e-12 45.4 0.0 2.9 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.1 EIE80047.1 - 6.6e-18 65.0 0.0 5.5e-11 42.7 0.0 2.9 2 0 0 2 2 2 2 PAS domain HATPase_c PF02518.21 EIE80047.1 - 7.1e-18 64.3 0.1 1.4e-17 63.4 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_4 PF08448.5 EIE80047.1 - 1.1e-14 54.3 0.0 4.5e-09 36.3 0.0 2.4 2 0 0 2 2 2 2 PAS fold Response_reg PF00072.19 EIE80047.1 - 1.1e-12 47.9 0.0 6e-11 42.3 0.0 2.6 2 0 0 2 2 2 1 Response regulator receiver domain Fer4_17 PF13534.1 EIE80047.1 - 2.3e-09 37.4 6.5 7.6e-09 35.7 4.5 2.0 1 0 0 1 1 1 1 4Fe-4S dicluster domain PAS PF00989.19 EIE80047.1 - 2.4e-09 36.9 0.0 2.6e-06 27.1 0.0 2.7 2 0 0 2 2 2 2 PAS fold Fer4_8 PF13183.1 EIE80047.1 - 1.8e-07 31.0 4.8 6.8e-07 29.2 3.3 2.1 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.2 EIE80047.1 - 0.0017 18.7 3.4 0.0053 17.1 2.3 2.0 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 EIE80047.1 - 0.0028 18.0 1.3 0.0028 18.0 0.9 3.6 3 1 1 4 4 4 2 4Fe-4S dicluster domain PAS_8 PF13188.1 EIE80047.1 - 0.0051 16.6 0.0 0.022 14.6 0.0 2.1 2 0 0 2 2 2 1 PAS domain YHYH PF14240.1 EIE80047.1 - 0.013 15.1 0.0 0.031 13.9 0.0 1.6 1 0 0 1 1 1 0 YHYH protein Fer4_10 PF13237.1 EIE80047.1 - 0.39 10.5 12.0 0.021 14.6 3.8 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_9 PF13187.1 EIE80047.1 - 9.5 6.5 11.9 1.8 8.8 1.7 2.9 2 1 1 3 3 2 0 4Fe-4S dicluster domain DUF1664 PF07889.7 EIE80048.1 - 9.4e-06 25.4 2.3 9.4e-06 25.4 1.6 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF1664) DUF883 PF05957.8 EIE80048.1 - 4.2e-05 23.8 19.2 0.018 15.4 4.9 3.2 1 1 2 3 3 3 2 Bacterial protein of unknown function (DUF883) ATP-synt_B PF00430.13 EIE80048.1 - 0.0049 16.6 26.2 0.04 13.7 8.2 2.6 1 1 2 3 3 3 2 ATP synthase B/B' CF(0) YtxH PF12732.2 EIE80048.1 - 0.0091 16.3 32.8 1.5e+04 -11.4 22.7 3.5 1 1 0 1 1 0 0 YtxH-like protein ApoO PF09769.4 EIE80048.1 - 0.011 15.4 2.9 0.48 10.1 0.0 2.5 1 1 1 2 2 2 0 Apolipoprotein O Apolipoprotein PF01442.13 EIE80048.1 - 0.097 12.1 17.2 0.2 11.1 11.9 1.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Tape_meas_lam_C PF09718.5 EIE80048.1 - 0.57 10.1 4.6 1.1 9.2 0.3 2.6 1 1 2 3 3 3 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) KfrA_N PF11740.3 EIE80048.1 - 1.8 9.0 13.3 1.4 9.3 1.0 2.5 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term DUF3584 PF12128.3 EIE80048.1 - 2.9 5.1 25.1 3.4 4.8 17.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Phe_tRNA-synt_N PF02912.13 EIE80048.1 - 2.9 7.6 18.0 1.3 8.7 0.3 3.4 1 1 3 4 4 4 0 Aminoacyl tRNA synthetase class II, N-terminal domain IncA PF04156.9 EIE80048.1 - 3.1 7.3 13.8 83 2.7 9.3 2.4 1 1 0 1 1 1 0 IncA protein DUF3391 PF11871.3 EIE80048.1 - 4.9 7.3 13.0 68 3.6 8.2 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) Prominin PF05478.6 EIE80048.1 - 7 4.0 9.9 3.6 4.9 5.1 1.6 1 1 1 2 2 2 0 Prominin Peptidase_M41 PF01434.13 EIE80049.1 - 3e-75 252.3 2.5 3e-75 252.3 1.8 1.9 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.24 EIE80049.1 - 8.7e-43 145.6 0.0 3.5e-42 143.7 0.0 2.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EIE80049.1 - 6.8e-07 29.4 0.2 0.012 15.7 0.0 4.3 2 1 1 3 3 3 1 AAA domain AAA_5 PF07728.9 EIE80049.1 - 1.1e-06 28.4 0.0 5.6e-06 26.1 0.0 2.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 EIE80049.1 - 1.7e-05 23.7 0.0 4.7e-05 22.2 0.0 1.7 1 0 0 1 1 1 1 TIP49 C-terminus AAA_17 PF13207.1 EIE80049.1 - 2.2e-05 25.2 0.0 0.00013 22.8 0.0 2.3 2 0 0 2 2 1 1 AAA domain RuvB_N PF05496.7 EIE80049.1 - 0.00012 21.1 0.0 0.00038 19.5 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 EIE80049.1 - 0.00015 21.7 0.1 0.0013 18.6 0.0 2.7 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EIE80049.1 - 0.00022 21.2 1.0 0.005 16.8 0.1 3.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 EIE80049.1 - 0.00022 20.8 0.1 0.00073 19.2 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 EIE80049.1 - 0.00076 19.3 0.2 0.0095 15.8 0.0 3.0 4 0 0 4 4 3 1 AAA domain AAA_25 PF13481.1 EIE80049.1 - 0.0012 18.3 0.8 0.055 12.8 0.2 2.7 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.8 EIE80049.1 - 0.0012 17.8 0.0 0.0029 16.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.16 EIE80049.1 - 0.0012 18.0 0.6 0.012 14.8 0.2 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 EIE80049.1 - 0.0017 17.8 0.1 0.0055 16.1 0.1 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 EIE80049.1 - 0.0033 17.3 0.0 0.065 13.1 0.0 2.9 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EIE80049.1 - 0.0048 16.0 0.0 0.014 14.5 0.0 1.8 1 0 0 1 1 1 1 Zeta toxin AAA_28 PF13521.1 EIE80049.1 - 0.0061 16.5 0.4 0.016 15.2 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_18 PF13238.1 EIE80049.1 - 0.016 15.4 0.0 0.076 13.3 0.0 2.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EIE80049.1 - 0.017 14.7 0.6 0.16 11.5 0.0 2.9 3 0 0 3 3 3 0 NACHT domain Sigma54_activ_2 PF14532.1 EIE80049.1 - 0.027 14.5 0.3 0.18 11.8 0.0 2.7 3 0 0 3 3 2 0 Sigma-54 interaction domain Sigma54_activat PF00158.21 EIE80049.1 - 0.059 12.8 0.9 0.35 10.3 0.0 2.7 4 0 0 4 4 4 0 Sigma-54 interaction domain KaiC PF06745.8 EIE80049.1 - 0.081 12.0 1.8 0.79 8.7 0.0 3.0 4 0 0 4 4 4 0 KaiC Syntaxin-6_N PF09177.6 EIE80049.1 - 2 8.8 12.1 0.054 13.9 0.6 3.7 4 0 0 4 4 2 0 Syntaxin 6, N-terminal DUF642 PF04862.7 EIE80050.1 - 0.00043 19.9 1.5 0.31 10.6 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF642) GPI-anchored PF10342.4 EIE80050.1 - 0.017 15.5 4.1 0.023 15.1 2.8 1.2 1 0 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family NigD PF12667.2 EIE80050.1 - 0.035 13.9 0.4 0.045 13.5 0.3 1.3 1 1 0 1 1 1 0 NigD-like protein DUF3108 PF11306.3 EIE80050.1 - 0.039 13.6 0.2 0.044 13.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3108) DUF1842 PF08896.5 EIE80050.1 - 0.041 13.6 0.1 0.062 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1842) TRAP-delta PF05404.7 EIE80050.1 - 0.058 12.8 0.3 0.13 11.6 0.1 1.6 1 1 1 2 2 2 0 Translocon-associated protein, delta subunit precursor (TRAP-delta) Flagellin_D3 PF08884.6 EIE80050.1 - 0.068 13.3 1.6 0.089 12.9 0.7 1.5 1 1 0 1 1 1 0 Flagellin D3 domain DUF3707 PF12499.3 EIE80050.1 - 2.6 8.3 7.8 5.3 7.3 0.8 2.1 1 1 1 2 2 2 0 Pherophorin DUF3425 PF11905.3 EIE80051.1 - 7.4e-11 42.0 0.6 2.1e-10 40.5 0.4 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) BCNT PF07572.7 EIE80052.1 - 8.5e-22 76.8 3.7 8.5e-22 76.8 2.5 2.0 2 0 0 2 2 2 1 Bucentaur or craniofacial development Prothymosin PF03247.9 EIE80052.1 - 0.016 15.3 5.0 0.016 15.3 3.5 3.3 4 0 0 4 4 4 0 Prothymosin/parathymosin family ScpA_ScpB PF02616.9 EIE80052.1 - 7.9 5.9 15.2 1.1 8.7 7.4 1.6 1 1 1 2 2 2 0 ScpA/B protein Zn_clus PF00172.13 EIE80054.1 - 0.00024 20.9 18.1 0.0004 20.2 12.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RhoGEF PF00621.15 EIE80055.1 - 2.3e-08 34.1 0.1 3.3e-08 33.6 0.1 1.2 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.24 EIE80056.1 - 0.00011 22.3 0.0 0.00015 21.8 0.0 1.2 1 0 0 1 1 1 1 PH domain AAA_25 PF13481.1 EIE80056.1 - 0.091 12.1 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain Gcd10p PF04189.8 EIE80058.1 - 3.8e-81 272.5 3.8 9.5e-81 271.1 2.6 1.6 1 1 0 1 1 1 1 Gcd10p family Cpn60_TCP1 PF00118.19 EIE80059.1 - 1.2e-149 499.0 4.5 1.5e-149 498.7 3.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family AAA PF00004.24 EIE80063.1 - 2.8e-21 76.1 0.0 4.9e-21 75.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.6 EIE80063.1 - 6.2e-08 32.4 0.0 1.3e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 BCS1 N terminal AAA_16 PF13191.1 EIE80063.1 - 7.1e-06 26.1 0.0 1.5e-05 25.0 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 EIE80063.1 - 3.1e-05 23.7 0.0 0.00013 21.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EIE80063.1 - 4.3e-05 22.6 0.0 7e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 EIE80063.1 - 0.0001 22.0 0.2 0.075 12.6 0.0 3.0 2 1 1 3 3 3 1 NACHT domain RNA_helicase PF00910.17 EIE80063.1 - 0.00064 19.8 0.0 0.0089 16.1 0.0 2.4 2 0 0 2 2 2 1 RNA helicase AAA_22 PF13401.1 EIE80063.1 - 0.00077 19.6 0.0 0.0019 18.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EIE80063.1 - 0.00092 20.0 0.0 0.0032 18.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.1 EIE80063.1 - 0.0036 16.9 0.2 0.0082 15.7 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EIE80063.1 - 0.0038 16.6 0.0 0.008 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 EIE80063.1 - 0.0085 15.2 0.0 0.019 14.1 0.0 1.6 1 0 0 1 1 1 1 KaiC DUF815 PF05673.8 EIE80063.1 - 0.0093 14.9 0.0 0.022 13.7 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 EIE80063.1 - 0.011 15.6 0.0 0.03 14.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.20 EIE80063.1 - 0.013 15.0 0.0 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_19 PF13245.1 EIE80063.1 - 0.017 14.8 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain AAA_11 PF13086.1 EIE80063.1 - 0.021 14.4 0.0 0.029 13.9 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EIE80063.1 - 0.049 13.9 0.0 0.14 12.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EIE80063.1 - 0.06 13.3 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EIE80063.1 - 0.071 12.5 0.1 0.33 10.3 0.0 2.0 1 1 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.8 EIE80063.1 - 0.071 11.8 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus Miro PF08477.8 EIE80063.1 - 0.073 13.5 0.1 0.24 11.9 0.0 1.9 2 0 0 2 2 1 0 Miro-like protein Arch_ATPase PF01637.13 EIE80063.1 - 0.081 12.6 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase DUF258 PF03193.11 EIE80063.1 - 0.093 11.9 0.0 0.23 10.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 cobW PF02492.14 EIE80063.1 - 0.095 12.1 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 EIE80063.1 - 0.095 12.5 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EIE80063.1 - 0.12 11.4 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Pribosyltran_N PF13793.1 EIE80063.1 - 0.13 12.0 0.1 0.4 10.4 0.0 1.8 2 0 0 2 2 1 0 N-terminal domain of ribose phosphate pyrophosphokinase NTPase_1 PF03266.10 EIE80063.1 - 0.14 11.8 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 NTPase Rap_GAP PF02145.10 EIE80064.1 - 1.2e-53 181.2 0.3 2.6e-53 180.2 0.0 1.7 2 0 0 2 2 2 1 Rap/ran-GAP zf-H2C2 PF09337.5 EIE80064.1 - 0.0038 16.6 0.2 0.0076 15.6 0.1 1.5 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger GLE1 PF07817.8 EIE80064.1 - 0.0062 15.5 0.7 0.29 10.0 0.0 2.6 3 0 0 3 3 3 1 GLE1-like protein PAP2 PF01569.16 EIE80064.1 - 0.053 13.1 1.0 0.12 12.0 0.7 1.6 1 0 0 1 1 1 0 PAP2 superfamily Prefoldin PF02996.12 EIE80066.1 - 2.9e-19 68.8 0.4 2.9e-19 68.8 0.3 3.1 3 0 0 3 3 3 1 Prefoldin subunit Prefoldin_3 PF13758.1 EIE80066.1 - 1.1e-10 41.1 0.2 1.1e-10 41.1 0.1 3.6 2 1 0 2 2 2 1 Prefoldin subunit DUF3835 PF12927.2 EIE80066.1 - 0.0034 18.3 3.7 0.0034 18.3 2.5 5.9 3 2 3 6 6 6 2 Domain of unknown function (DUF3835) Pkinase PF00069.20 EIE80067.1 - 1.6e-58 197.8 0.0 1.9e-58 197.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE80067.1 - 5.6e-21 74.7 0.0 2.6e-19 69.2 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EIE80067.1 - 3.7e-06 26.8 0.6 2.1e-05 24.3 0.3 2.1 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EIE80067.1 - 0.0032 17.0 0.2 0.0075 15.8 0.1 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 EIE80067.1 - 0.011 14.8 0.1 0.018 14.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EIE80067.1 - 0.062 12.6 0.3 1.5 8.0 0.0 2.3 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL C1_1 PF00130.17 EIE80069.1 - 0.00041 20.0 0.1 0.00043 19.9 0.1 1.1 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-FCS PF06467.9 EIE80069.1 - 0.038 13.6 0.8 0.043 13.4 0.6 1.2 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif zf-CCHC_4 PF14392.1 EIE80069.1 - 0.067 12.8 0.4 0.085 12.5 0.3 1.2 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.1 EIE80069.1 - 0.15 11.7 1.7 0.18 11.5 1.2 1.2 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.18 EIE80069.1 - 0.23 11.4 3.1 0.28 11.1 2.1 1.2 1 0 0 1 1 1 0 Zinc knuckle PC-Esterase PF13839.1 EIE80070.1 - 2.7e-29 102.8 0.1 3.2e-29 102.5 0.1 1.1 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Sec10 PF07393.6 EIE80071.1 - 1.4e-170 568.9 13.4 3.2e-147 491.7 7.1 2.1 1 1 1 2 2 2 2 Exocyst complex component Sec10 Rhomboid PF01694.17 EIE80072.1 - 4.6e-20 72.1 5.3 4.6e-20 72.1 3.7 1.6 1 1 1 2 2 2 1 Rhomboid family DUF1751 PF08551.5 EIE80072.1 - 0.00021 21.5 0.0 0.00034 20.8 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) DUF832 PF05734.6 EIE80072.1 - 0.052 12.7 0.1 0.071 12.3 0.1 1.2 1 0 0 1 1 1 0 Herpesvirus protein of unknown function (DUF832) DUF4010 PF13194.1 EIE80072.1 - 0.054 12.8 0.2 0.067 12.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4010) Hexapep PF00132.19 EIE80073.1 - 1.8e-09 36.6 11.7 4.9e-06 25.8 2.3 3.1 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EIE80073.1 - 1.3 8.6 14.5 2.4 7.7 4.3 2.6 2 1 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase Lzipper-MIP1 PF14389.1 EIE80075.1 - 0.004 17.2 0.4 0.0058 16.7 0.3 1.2 1 0 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 DUF2397 PF09660.5 EIE80075.1 - 0.0062 15.1 0.3 0.0071 14.9 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2397) ChaB PF06150.7 EIE80075.1 - 0.03 14.1 0.1 0.05 13.3 0.1 1.4 1 0 0 1 1 1 0 ChaB DUF972 PF06156.8 EIE80075.1 - 0.085 13.2 0.8 0.12 12.7 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) V_ATPase_I PF01496.14 EIE80075.1 - 0.2 9.4 1.2 0.23 9.2 0.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 EIE80075.1 - 0.23 11.0 1.9 0.26 10.8 1.3 1.1 1 0 0 1 1 1 0 IncA protein HTH_Tnp_Tc3_2 PF01498.13 EIE80076.1 - 9e-07 28.8 0.9 4.1e-06 26.7 0.1 2.2 2 0 0 2 2 2 1 Transposase HTH_Tnp_ISL3 PF13542.1 EIE80076.1 - 0.00052 19.1 0.3 0.0015 17.6 0.1 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_23 PF13384.1 EIE80076.1 - 0.00071 19.1 0.2 0.0084 15.7 0.0 2.5 3 0 0 3 3 3 1 Homeodomain-like domain HTH_32 PF13565.1 EIE80076.1 - 0.013 16.2 0.6 7.1 7.5 0.0 2.9 1 1 2 3 3 3 0 Homeodomain-like domain HTH_28 PF13518.1 EIE80076.1 - 0.015 15.3 0.0 0.039 13.9 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_IclR PF09339.5 EIE80076.1 - 0.026 14.1 0.1 0.051 13.1 0.1 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain Mto2_bdg PF12808.2 EIE80078.1 - 0.22 11.6 6.9 3.6 7.7 0.3 3.4 3 0 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Transposase_21 PF02992.9 EIE80080.1 - 3.8e-23 81.7 0.1 3.8e-23 81.7 0.1 1.8 2 0 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.1 EIE80080.1 - 1.6e-05 24.3 0.5 3.2e-05 23.3 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) DDE_3 PF13358.1 EIE80081.1 - 5.9e-17 61.7 0.0 7.8e-17 61.3 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE80082.1 - 1.2e-15 57.3 2.0 5.3e-15 55.2 0.2 2.2 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.1 EIE80082.1 - 5.4e-09 35.4 0.0 6.3e-06 25.6 0.0 2.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.1 EIE80082.1 - 5.9e-09 36.0 0.1 1.1e-08 35.2 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn helix HTH_7 PF02796.10 EIE80082.1 - 9.3e-09 35.0 2.7 5.1e-06 26.2 0.4 3.3 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase HTH_11 PF08279.7 EIE80082.1 - 5e-07 29.2 0.4 0.0003 20.3 0.0 2.6 2 0 0 2 2 2 1 HTH domain HTH_36 PF13730.1 EIE80082.1 - 2.8e-06 27.3 1.9 0.00013 22.0 0.3 2.9 2 1 0 3 3 3 1 Helix-turn-helix domain HTH_24 PF13412.1 EIE80082.1 - 1e-05 24.7 1.0 0.0098 15.2 0.1 2.8 3 0 0 3 3 3 2 Winged helix-turn-helix DNA-binding HTH_28 PF13518.1 EIE80082.1 - 3e-05 23.9 0.0 0.019 14.9 0.0 2.8 3 0 0 3 3 2 1 Helix-turn-helix domain HTH_38 PF13936.1 EIE80082.1 - 3.1e-05 23.4 0.2 0.00044 19.7 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_32 PF13565.1 EIE80082.1 - 3.2e-05 24.6 0.5 0.00045 20.9 0.0 2.7 2 1 1 3 3 2 1 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.1 EIE80082.1 - 9e-05 21.5 0.3 0.06 12.5 0.0 2.6 3 0 0 3 3 3 2 Helix-turn-helix domain of transposase family ISL3 LacI PF00356.16 EIE80082.1 - 0.0004 19.9 0.4 0.71 9.5 0.0 2.6 2 0 0 2 2 2 2 Bacterial regulatory proteins, lacI family HTH_3 PF01381.17 EIE80082.1 - 0.0012 18.6 0.8 0.12 12.2 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix Trp_repressor PF01371.14 EIE80082.1 - 0.0015 18.3 0.1 0.019 14.8 0.1 2.2 2 0 0 2 2 2 1 Trp repressor protein HTH_21 PF13276.1 EIE80082.1 - 0.0016 18.4 0.4 0.0057 16.6 0.1 2.1 2 0 0 2 2 2 1 HTH-like domain HTH_AsnC-type PF13404.1 EIE80082.1 - 0.0019 17.6 0.0 0.0071 15.8 0.0 1.9 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain HTH_6 PF01418.12 EIE80082.1 - 0.0021 17.7 0.4 0.33 10.7 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain, rpiR family GntR PF00392.16 EIE80082.1 - 0.003 16.9 0.1 0.92 8.9 0.0 2.5 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family HTH_33 PF13592.1 EIE80082.1 - 0.0039 16.6 0.0 0.0093 15.4 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn helix GerE PF00196.14 EIE80082.1 - 0.005 16.1 2.0 0.0053 16.0 0.1 2.0 3 0 0 3 3 1 1 Bacterial regulatory proteins, luxR family Phage_terminase PF10668.4 EIE80082.1 - 0.006 16.3 1.6 0.0078 15.9 0.0 1.9 2 0 0 2 2 1 1 Phage terminase small subunit TrmB PF01978.14 EIE80082.1 - 0.0075 15.9 0.1 0.13 12.0 0.1 2.4 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_40 PF14493.1 EIE80082.1 - 0.0079 16.3 0.0 0.013 15.6 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_1_2 PF13022.1 EIE80082.1 - 0.012 15.4 0.1 0.37 10.5 0.0 2.2 1 1 1 2 2 2 0 Helix-turn-helix of insertion element transposase DUF977 PF06163.6 EIE80082.1 - 0.012 15.3 0.5 2.5 7.8 0.0 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF977) Sigma54_DBD PF04552.8 EIE80082.1 - 0.016 14.6 0.8 0.14 11.6 0.1 2.4 2 1 0 2 2 2 0 Sigma-54, DNA binding domain Fe_dep_repress PF01325.14 EIE80082.1 - 0.029 14.3 0.8 1.8 8.5 0.1 2.4 2 0 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain RepL PF05732.6 EIE80082.1 - 0.032 13.4 0.1 0.94 8.6 0.0 2.1 2 0 0 2 2 2 0 Firmicute plasmid replication protein (RepL) HTH_10 PF04967.7 EIE80082.1 - 0.033 13.7 0.1 0.93 9.1 0.0 2.3 2 0 0 2 2 2 0 HTH DNA binding domain HTH_5 PF01022.15 EIE80082.1 - 0.046 13.3 0.2 0.87 9.3 0.0 2.5 2 1 0 2 2 2 0 Bacterial regulatory protein, arsR family Sigma70_r4_2 PF08281.7 EIE80082.1 - 0.056 12.9 0.5 0.95 8.9 0.1 2.4 2 0 0 2 2 2 0 Sigma-70, region 4 KorB PF08535.5 EIE80082.1 - 0.059 13.5 0.1 0.15 12.2 0.0 1.7 1 1 0 1 1 1 0 KorB domain HTH_17 PF12728.2 EIE80082.1 - 0.059 13.6 0.1 3.1 8.1 0.0 2.8 3 0 0 3 3 2 0 Helix-turn-helix domain RepB PF07506.6 EIE80082.1 - 0.067 13.0 0.3 0.72 9.6 0.2 2.2 1 1 0 1 1 1 0 RepB plasmid partitioning protein 3A PF00803.13 EIE80082.1 - 0.07 12.1 0.5 0.093 11.7 0.3 1.2 1 0 0 1 1 1 0 3A/RNA2 movement protein family HTH_22 PF13309.1 EIE80082.1 - 0.085 12.6 0.3 0.27 11.0 0.1 1.9 2 0 0 2 2 1 0 HTH domain HTH_IclR PF09339.5 EIE80082.1 - 0.13 11.8 0.0 1.2 8.7 0.0 2.4 3 0 0 3 3 3 0 IclR helix-turn-helix domain RVT_1 PF00078.22 EIE80084.1 - 1.1e-11 44.5 0.0 1.4e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) EF_assoc_1 PF08355.7 EIE80084.1 - 0.13 11.5 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 EF hand associated DDE_3 PF13358.1 EIE80085.1 - 2e-14 53.5 0.2 2.9e-14 53.0 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Cas_Csx9 PF09658.5 EIE80085.1 - 0.056 12.2 0.0 0.081 11.7 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csx9) RabGAP-TBC PF00566.13 EIE80089.1 - 1.3e-31 109.8 0.5 3.5e-19 69.1 0.3 2.4 1 1 1 2 2 2 2 Rab-GTPase-TBC domain SYF2 PF08231.7 EIE80090.1 - 3.3e-41 140.9 17.7 3.3e-41 140.9 12.3 2.6 2 1 0 2 2 2 1 SYF2 splicing factor Snurportin1 PF11538.3 EIE80090.1 - 1.3 8.8 7.0 17 5.3 4.7 2.7 1 1 1 2 2 2 0 Snurportin1 UPF0014 PF03649.8 EIE80091.1 - 4.2e-33 114.5 9.0 5e-33 114.3 6.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0014) FtsX PF02687.16 EIE80091.1 - 0.019 14.7 17.0 0.031 14.0 7.1 2.6 1 1 1 2 2 2 0 FtsX-like permease family BPD_transp_1 PF00528.17 EIE80091.1 - 0.053 13.0 10.5 0.068 12.6 7.3 1.1 1 0 0 1 1 1 0 Binding-protein-dependent transport system inner membrane component PGG PF13962.1 EIE80091.1 - 0.58 9.7 4.4 0.9 9.1 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF4231 PF14015.1 EIE80091.1 - 2.5 8.1 5.3 3.2 7.7 0.6 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) Methyltransf_26 PF13659.1 EIE80092.1 - 2e-10 40.7 0.0 3.4e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIE80092.1 - 2.5e-09 36.9 0.2 5.4e-09 35.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EIE80092.1 - 4.4e-08 32.6 0.0 9e-08 31.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 EIE80092.1 - 3.4e-07 30.8 0.0 7e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EIE80092.1 - 1.8e-05 24.0 0.4 3.2e-05 23.1 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.13 EIE80092.1 - 5e-05 22.9 0.0 8.9e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_Mtase PF02384.11 EIE80092.1 - 6.7e-05 22.1 0.0 0.00012 21.2 0.0 1.5 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_25 PF13649.1 EIE80092.1 - 9.9e-05 22.6 0.0 0.00089 19.5 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIE80092.1 - 0.0012 19.3 0.0 0.0028 18.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EIE80092.1 - 0.0017 18.0 0.1 0.063 12.9 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain Eco57I PF07669.6 EIE80092.1 - 0.0034 17.6 0.0 0.0083 16.4 0.0 1.6 1 0 0 1 1 1 1 Eco57I restriction-modification methylase PseudoU_synth_2 PF00849.17 EIE80092.1 - 0.0039 17.0 0.0 0.0053 16.6 0.0 1.4 1 1 0 1 1 1 1 RNA pseudouridylate synthase Ubie_methyltran PF01209.13 EIE80092.1 - 0.0052 15.9 0.6 0.0092 15.1 0.4 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_10 PF05971.7 EIE80092.1 - 0.0058 15.8 0.0 0.0094 15.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF890) CMAS PF02353.15 EIE80092.1 - 0.011 14.8 0.1 0.1 11.6 0.0 2.2 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Methyltransf_20 PF12147.3 EIE80092.1 - 0.081 11.7 0.0 0.17 10.7 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_11 PF08241.7 EIE80092.1 - 0.093 13.2 0.0 0.28 11.6 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain HEAT PF02985.17 EIE80093.1 - 4.1e-05 23.3 0.0 0.024 14.7 0.0 2.8 2 0 0 2 2 2 2 HEAT repeat UVR PF02151.14 EIE80093.1 - 0.00086 18.7 5.2 0.00094 18.6 0.2 2.7 2 0 0 2 2 2 1 UvrB/uvrC motif Cnd1 PF12717.2 EIE80093.1 - 0.0092 15.8 0.2 0.092 12.5 0.0 2.5 2 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Allantoicase PF03561.10 EIE80093.1 - 0.067 12.6 0.2 0.22 11.0 0.0 1.9 2 0 0 2 2 2 0 Allantoicase repeat DUF3236 PF11576.3 EIE80093.1 - 0.19 11.1 2.9 0.46 9.8 0.3 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3236) ADH_N PF08240.7 EIE80094.1 - 0.11 12.3 1.4 0.31 10.8 0.9 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain RVT_1 PF00078.22 EIE80097.1 - 3.1e-10 39.7 0.1 1e-09 38.0 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 EIE80097.1 - 2.5e-05 24.6 0.0 5.6e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 EIE80097.1 - 4.9e-05 23.1 0.2 0.00015 21.5 0.1 1.9 1 0 0 1 1 1 1 Retroviral aspartyl protease RNase_H PF00075.19 EIE80097.1 - 0.037 14.3 0.0 0.12 12.7 0.0 1.8 1 0 0 1 1 1 0 RNase H HTH_Tnp_Tc3_2 PF01498.13 EIE80098.1 - 3.2e-06 27.0 1.5 4.7e-06 26.5 0.3 1.8 2 1 0 2 2 2 1 Transposase HTH_Tnp_4 PF13613.1 EIE80098.1 - 0.00017 21.0 0.0 0.00033 20.1 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease HTH_23 PF13384.1 EIE80098.1 - 0.0012 18.3 0.0 0.0031 17.1 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_30 PF13556.1 EIE80098.1 - 0.08 12.5 0.0 0.19 11.3 0.0 1.6 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain HTH_36 PF13730.1 EIE80098.1 - 0.082 13.0 0.1 0.83 9.8 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain DDE_3 PF13358.1 EIE80099.1 - 1.1e-17 64.1 0.0 2.9e-17 62.7 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE80099.1 - 2e-08 34.1 0.5 7.1e-08 32.3 0.4 2.0 2 1 0 2 2 2 1 Transposase DDE_3 PF13358.1 EIE80101.1 - 1.1e-17 64.1 0.0 2.9e-17 62.7 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE80101.1 - 2e-08 34.1 0.5 7.1e-08 32.3 0.4 2.0 2 1 0 2 2 2 1 Transposase zf-H2C2 PF09337.5 EIE80102.1 - 0.00095 18.5 0.3 0.002 17.5 0.1 1.6 1 1 0 1 1 1 1 His(2)-Cys(2) zinc finger zf-3CxxC PF13695.1 EIE80102.1 - 0.11 12.7 0.6 0.18 12.0 0.1 1.6 2 1 0 2 2 2 0 Zinc-binding domain Spuma_A9PTase PF03539.9 EIE80103.1 - 0.014 15.3 0.1 0.016 15.1 0.0 1.1 1 0 0 1 1 1 0 Spumavirus aspartic protease (A9) DUF1759 PF03564.10 EIE80104.1 - 0.00014 21.7 0.4 0.00021 21.1 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) Retrotrans_gag PF03732.12 EIE80104.1 - 0.0006 19.8 0.3 0.0016 18.4 0.0 1.8 2 0 0 2 2 2 1 Retrotransposon gag protein Retrotrans_gag PF03732.12 EIE80105.1 - 6.7e-09 35.7 2.2 1.7e-08 34.4 0.4 2.1 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.18 EIE80105.1 - 0.0012 18.6 3.3 0.0018 18.1 2.3 1.3 1 0 0 1 1 1 1 Zinc knuckle DUF3573 PF12097.3 EIE80105.1 - 0.0088 14.6 0.8 0.015 13.9 0.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3573) RVT_1 PF00078.22 EIE80106.1 - 4.3e-14 52.3 0.0 7.3e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 EIE80106.1 - 5.4e-08 33.2 0.1 1.3e-07 32.0 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EIE80106.1 - 9.7e-06 25.3 0.1 2.1e-05 24.2 0.1 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 EIE80106.1 - 0.0005 19.9 0.1 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 EIE80106.1 - 0.012 15.1 0.0 0.05 13.1 0.0 2.0 2 0 0 2 2 2 0 Aspartyl protease rve PF00665.21 EIE80107.1 - 1.6e-21 76.5 0.0 2.7e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 EIE80107.1 - 0.001 18.5 0.4 0.0029 17.1 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain Methyltransf_23 PF13489.1 EIE80108.1 - 1.8e-10 40.7 0.0 2.2e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIE80108.1 - 8.1e-08 32.6 0.0 1.5e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIE80108.1 - 6.1e-05 23.4 0.0 0.00012 22.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DUF3419 PF11899.3 EIE80108.1 - 0.018 13.7 0.0 0.018 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3419) Ubie_methyltran PF01209.13 EIE80108.1 - 0.051 12.6 0.0 0.14 11.2 0.0 1.8 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EIE80108.1 - 0.064 12.8 0.0 0.066 12.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Lipase_3 PF01764.20 EIE80109.1 - 0.00029 20.4 0.0 0.62 9.6 0.0 2.3 1 1 1 2 2 2 2 Lipase (class 3) FcoT PF10862.3 EIE80109.1 - 0.01 15.4 0.1 0.088 12.3 0.0 2.1 1 1 1 2 2 2 0 FcoT-like thioesterase domain Glyco_transf_8 PF01501.15 EIE80110.1 - 3.1e-34 118.4 3.2 4.6e-34 117.8 2.2 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 EIE80110.1 - 0.018 14.4 0.1 0.29 10.4 0.0 2.1 2 0 0 2 2 2 0 Mannosyltransferase putative WD40 PF00400.27 EIE80112.1 - 1.3e-36 123.1 16.6 2.3e-06 27.2 0.0 10.1 10 0 0 10 10 10 8 WD domain, G-beta repeat TPT PF03151.11 EIE80113.1 - 1.1e-27 96.5 22.1 1.7e-26 92.7 7.6 2.1 2 0 0 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.6 EIE80113.1 - 1.7e-16 60.0 22.5 3.3e-16 59.0 15.6 1.3 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EIE80113.1 - 3.9e-09 36.6 24.4 3.9e-06 26.9 3.9 3.1 3 0 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 EIE80113.1 - 0.00043 20.4 18.6 0.022 14.9 2.8 2.6 1 1 0 2 2 2 2 Multidrug resistance efflux transporter Neurensin PF14927.1 EIE80113.1 - 0.27 10.6 2.7 0.57 9.5 0.4 2.1 2 0 0 2 2 2 0 Neurensin Nuc_sug_transp PF04142.10 EIE80113.1 - 0.74 8.8 18.2 98 1.9 12.6 2.2 1 1 1 2 2 2 0 Nucleotide-sugar transporter V_ATPase_I PF01496.14 EIE80114.1 - 3.6e-285 947.6 0.2 4.1e-285 947.5 0.2 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family IncA PF04156.9 EIE80114.1 - 0.0019 17.8 3.4 0.0019 17.8 2.4 3.4 5 0 0 5 5 5 1 IncA protein Herpes_gE PF02480.11 EIE80114.1 - 0.0063 14.8 0.0 0.014 13.6 0.0 1.5 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E bZIP_1 PF00170.16 EIE80114.1 - 0.13 12.2 4.9 0.028 14.3 0.9 1.8 2 0 0 2 2 2 0 bZIP transcription factor DUF4337 PF14235.1 EIE80114.1 - 1.1 9.1 3.6 0.74 9.6 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) bZIP_2 PF07716.10 EIE80114.1 - 1.2 9.0 5.2 0.16 11.8 0.4 1.9 2 0 0 2 2 2 0 Basic region leucine zipper SPX PF03105.14 EIE80115.1 - 4.1e-21 75.9 16.2 5.1e-21 75.6 11.2 1.1 1 0 0 1 1 1 1 SPX domain SlyX PF04102.7 EIE80115.1 - 0.027 14.8 4.1 0.25 11.7 0.1 2.7 3 0 0 3 3 3 0 SlyX Sarcoglycan_2 PF05510.8 EIE80116.1 - 0.0033 15.7 0.6 0.0036 15.6 0.4 1.0 1 0 0 1 1 1 1 Sarcoglycan alpha/epsilon OSTbeta PF15048.1 EIE80116.1 - 0.0078 16.2 0.0 0.009 16.0 0.0 1.1 1 0 0 1 1 1 1 Organic solute transporter subunit beta protein Herpes_gE PF02480.11 EIE80116.1 - 0.0085 14.4 0.0 0.011 14.0 0.0 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E DAG1 PF05454.6 EIE80116.1 - 0.0086 15.2 0.3 0.0089 15.2 0.1 1.3 1 1 0 1 1 1 1 Dystroglycan (Dystrophin-associated glycoprotein 1) Vpu PF00558.14 EIE80116.1 - 0.011 15.2 0.1 0.018 14.5 0.1 1.3 1 0 0 1 1 1 0 Vpu protein SCIMP PF15050.1 EIE80116.1 - 0.013 15.3 0.0 0.016 15.0 0.0 1.2 1 0 0 1 1 1 0 SCIMP protein TMEM154 PF15102.1 EIE80116.1 - 0.017 14.8 0.1 0.022 14.4 0.0 1.3 1 1 0 1 1 1 0 TMEM154 protein family Sre PF03125.13 EIE80116.1 - 0.02 13.8 0.6 0.031 13.1 0.4 1.2 1 0 0 1 1 1 0 C. elegans Sre G protein-coupled chemoreceptor Shisa PF13908.1 EIE80116.1 - 0.03 14.5 0.8 0.039 14.1 0.5 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator EphA2_TM PF14575.1 EIE80116.1 - 0.043 14.2 0.1 0.071 13.5 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF318 PF03773.8 EIE80116.1 - 0.048 12.6 0.0 0.051 12.5 0.0 1.1 1 0 0 1 1 1 0 Predicted permease PgaD PF13994.1 EIE80116.1 - 0.048 13.1 0.0 0.059 12.8 0.0 1.2 1 0 0 1 1 1 0 PgaD-like protein DUF3824 PF12868.2 EIE80116.1 - 0.065 14.1 0.0 0.075 13.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) DUF4097 PF13349.1 EIE80116.1 - 0.068 12.7 0.1 0.2 11.1 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4097) DUF1049 PF06305.6 EIE80116.1 - 0.077 12.4 0.1 0.077 12.4 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) NST1 PF13945.1 EIE80116.1 - 0.098 12.7 0.4 0.13 12.3 0.3 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator Rifin_STEVOR PF02009.11 EIE80116.1 - 0.11 12.0 0.9 0.17 11.5 0.6 1.3 1 0 0 1 1 1 0 Rifin/stevor family IncA PF04156.9 EIE80116.1 - 0.12 11.9 0.3 0.17 11.4 0.2 1.3 1 1 0 1 1 1 0 IncA protein DUF1191 PF06697.7 EIE80116.1 - 0.12 11.1 0.1 0.23 10.2 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1191) Bac_Ubq_Cox PF01654.12 EIE80116.1 - 0.3 9.4 1.5 0.68 8.2 0.3 1.8 1 1 1 2 2 2 0 Bacterial Cytochrome Ubiquinol Oxidase DUF4083 PF13314.1 EIE80116.1 - 1.3 8.8 3.9 0.32 10.8 0.6 1.6 2 0 0 2 2 1 0 Domain of unknown function (DUF4083) TMEM51 PF15345.1 EIE80116.1 - 2 8.0 4.2 0.38 10.4 0.1 1.7 1 1 0 2 2 2 0 Transmembrane protein 51 Peptidase_S15 PF02129.13 EIE80117.1 - 1.1e-05 25.0 0.0 1.2e-05 24.8 0.0 1.0 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.2 EIE80117.1 - 0.019 14.8 0.0 0.019 14.8 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EIE80117.1 - 0.12 12.2 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Putative lysophospholipase PTPS PF01242.14 EIE80118.1 - 6.5e-32 109.7 0.1 8.2e-32 109.4 0.1 1.1 1 0 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase TFR_dimer PF04253.10 EIE80119.1 - 2.2e-22 78.9 0.0 3.4e-22 78.3 0.0 1.3 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 EIE80119.1 - 1.2e-17 64.2 0.0 2.2e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EIE80119.1 - 2.5e-05 23.8 0.0 5.2e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 PA domain Swi5 PF07061.6 EIE80119.1 - 0.01 15.6 0.5 0.039 13.7 0.1 2.2 2 1 0 2 2 2 0 Swi5 Peptidase_M20 PF01546.23 EIE80119.1 - 0.011 15.3 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Nicastrin PF05450.10 EIE80119.1 - 0.048 12.8 0.0 0.13 11.4 0.0 1.7 1 0 0 1 1 1 0 Nicastrin YvrJ PF12841.2 EIE80119.1 - 0.12 11.6 1.8 12 5.3 0.0 3.4 3 0 0 3 3 3 0 YvrJ protein family UPF0014 PF03649.8 EIE80120.1 - 1.8e-30 105.9 7.2 1.8e-30 105.9 5.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0014) TORC_N PF12884.2 EIE80121.1 - 1.2 9.6 4.6 1.2 9.7 0.3 2.8 2 1 1 3 3 3 0 Transducer of regulated CREB activity, N terminus Mnd1 PF03962.10 EIE80121.1 - 8.1 6.0 24.9 9.3 5.8 6.5 2.2 1 1 2 3 3 3 0 Mnd1 family APG6 PF04111.7 EIE80121.1 - 8.2 5.3 26.4 0.42 9.5 11.6 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 Pkinase PF00069.20 EIE80122.1 - 5.6e-15 55.1 0.0 6.4e-07 28.7 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Peptidase_M41 PF01434.13 EIE80123.1 - 2.6e-76 255.7 0.0 4.9e-76 254.9 0.0 1.4 2 0 0 2 2 1 1 Peptidase family M41 AAA PF00004.24 EIE80123.1 - 2.6e-43 147.4 0.0 6.4e-43 146.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 EIE80123.1 - 1.5e-08 34.7 0.0 7.2e-08 32.5 0.0 2.2 2 0 0 2 2 2 1 FtsH Extracellular AAA_17 PF13207.1 EIE80123.1 - 0.00077 20.2 0.0 0.003 18.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EIE80123.1 - 0.0018 18.4 0.0 0.081 13.0 0.0 2.8 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.8 EIE80123.1 - 0.0046 15.7 0.0 0.0074 15.0 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA_19 PF13245.1 EIE80123.1 - 0.0056 16.4 1.0 0.018 14.7 0.7 1.8 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 EIE80123.1 - 0.0057 15.7 0.0 0.011 14.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 EIE80123.1 - 0.01 15.2 0.0 0.019 14.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.9 EIE80123.1 - 0.016 14.9 1.0 0.06 13.0 0.0 2.5 3 1 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EIE80123.1 - 0.017 15.1 0.2 0.2 11.5 0.1 2.6 1 1 1 2 2 2 0 AAA ATPase domain Mg_chelatase PF01078.16 EIE80123.1 - 0.045 12.9 0.4 0.35 10.0 0.2 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 EIE80123.1 - 0.054 12.5 0.1 0.13 11.3 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin CARD PF00619.16 EIE80123.1 - 0.06 13.1 0.3 0.21 11.4 0.2 1.9 1 0 0 1 1 1 0 Caspase recruitment domain AAA_25 PF13481.1 EIE80123.1 - 0.062 12.7 0.1 0.16 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.9 EIE80123.1 - 0.075 12.9 0.0 0.27 11.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 EIE80123.1 - 0.082 13.2 0.0 0.47 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain Sec7 PF01369.15 EIE80123.1 - 0.083 12.5 0.1 0.17 11.5 0.1 1.4 1 0 0 1 1 1 0 Sec7 domain AAA_33 PF13671.1 EIE80123.1 - 0.11 12.3 0.1 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EIE80123.1 - 0.14 12.1 0.3 0.43 10.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain ELFV_dehydrog PF00208.16 EIE80124.1 - 4.5e-57 193.4 1.8 6.4e-54 183.1 1.2 2.3 1 1 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 EIE80124.1 - 1.7e-46 157.0 0.0 2.6e-46 156.4 0.0 1.3 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 2-Hacid_dh_C PF02826.14 EIE80124.1 - 0.00042 19.5 0.1 0.00076 18.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EIE80124.1 - 0.0017 17.9 0.0 0.003 17.1 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.1 EIE80124.1 - 0.013 15.7 0.0 0.035 14.3 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding MotB_plug PF13677.1 EIE80125.1 - 0.16 11.3 0.2 0.16 11.3 0.1 1.4 2 0 0 2 2 2 0 Membrane MotB of proton-channel complex MotA/MotB PAP_central PF04928.12 EIE80126.1 - 5.7e-106 352.9 0.1 1.2e-105 351.9 0.0 1.5 2 0 0 2 2 2 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 EIE80126.1 - 7.4e-37 126.2 0.3 7.4e-37 126.2 0.2 1.8 2 0 0 2 2 2 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 EIE80126.1 - 3.3e-08 33.7 0.0 9.3e-08 32.2 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain TraG-D_C PF12696.2 EIE80126.1 - 0.029 14.2 0.9 0.059 13.2 0.6 1.4 1 0 0 1 1 1 0 TraM recognition site of TraD and TraG DUF1495 PF07381.6 EIE80126.1 - 0.043 13.4 0.4 15 5.2 0.0 3.3 3 0 0 3 3 3 0 Winged helix DNA-binding domain (DUF1495) WD40 PF00400.27 EIE80127.1 - 4.6e-29 99.2 12.4 4.2e-07 29.6 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat TLD PF07534.11 EIE80128.1 - 1.1e-38 132.3 1.4 1.3e-38 132.1 1.0 1.0 1 0 0 1 1 1 1 TLD DUF3688 PF12461.3 EIE80128.1 - 0.067 13.5 0.2 0.098 13.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3688) DUF3137 PF11335.3 EIE80129.1 - 0.00022 20.9 0.0 0.00028 20.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3137) Metallophos PF00149.23 EIE80131.1 - 3.5e-07 29.8 0.0 5.1e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ras PF00071.17 EIE80132.1 - 1.6e-24 86.1 0.3 1.3e-21 76.6 0.0 2.1 1 1 1 2 2 2 2 Ras family Miro PF08477.8 EIE80132.1 - 2.4e-08 34.4 0.0 4.2e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIE80132.1 - 4.7e-05 22.6 0.3 0.00011 21.5 0.1 1.5 1 1 1 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EIE80132.1 - 0.06 12.7 0.0 2.8 7.3 0.0 1.9 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain Pkinase PF00069.20 EIE80133.1 - 3.7e-59 199.9 0.0 4.4e-59 199.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE80133.1 - 4.1e-41 140.7 0.0 5.4e-41 140.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE80133.1 - 6e-05 22.1 0.0 0.00028 19.9 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.6 EIE80133.1 - 0.0057 15.5 0.0 0.027 13.3 0.0 2.0 2 0 0 2 2 2 1 Seadornavirus VP7 DUF659 PF04937.10 EIE80133.1 - 0.13 11.7 0.1 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) APH PF01636.18 EIE80133.1 - 0.15 11.7 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Lactate_perm PF02652.9 EIE80134.1 - 1.2e-96 324.2 24.5 4.4e-79 266.3 8.7 2.1 1 1 1 2 2 2 2 L-lactate permease NUDIX PF00293.23 EIE80135.1 - 6e-08 32.4 0.0 7.8e-08 32.0 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain Tubulin-binding PF00418.14 EIE80136.1 - 2.9e-83 273.1 67.2 2.2e-11 43.2 1.3 10.0 10 0 0 10 10 10 9 Tau and MAP protein, tubulin-binding repeat Mago_nashi PF02792.9 EIE80136.1 - 0.0018 17.9 2.4 49 3.5 0.0 5.4 2 1 5 7 7 7 0 Mago nashi protein Tombus_P33 PF08500.5 EIE80136.1 - 0.0089 15.7 7.0 16 5.1 0.1 6.0 3 2 3 6 6 6 1 Tombusvirus p33 Luciferase_3H PF10284.4 EIE80136.1 - 0.24 11.3 11.0 1.4e+02 2.5 0.0 6.6 8 0 0 8 8 8 0 Luciferase helical bundle domain Tox-REase-3 PF15647.1 EIE80136.1 - 0.5 10.1 7.4 6.4 6.6 0.1 4.1 3 1 3 6 6 6 0 Restriction endonuclease fold toxin 3 Tubulin PF00091.20 EIE80137.1 - 1.1e-70 237.7 0.0 1.5e-70 237.3 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EIE80137.1 - 2e-49 166.7 0.0 3.2e-49 166.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EIE80137.1 - 0.00034 20.1 0.0 0.00058 19.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Homeobox PF00046.24 EIE80138.1 - 4.4e-21 74.2 2.6 7.2e-21 73.5 1.8 1.4 1 0 0 1 1 1 1 Homeobox domain CrtC PF07143.6 EIE80138.1 - 0.04 13.2 0.7 0.052 12.8 0.5 1.1 1 0 0 1 1 1 0 Hydroxyneurosporene synthase (CrtC) Homeobox_KN PF05920.6 EIE80138.1 - 0.043 13.5 1.6 0.051 13.2 0.4 1.7 2 0 0 2 2 2 0 Homeobox KN domain RNA_pol_I_A49 PF06870.7 EIE80138.1 - 0.043 12.3 0.3 0.068 11.7 0.1 1.4 1 1 0 1 1 1 0 A49-like RNA polymerase I associated factor NeA_P2 PF12312.3 EIE80138.1 - 0.046 12.9 0.8 0.069 12.3 0.6 1.3 1 0 0 1 1 1 0 Nepovirus subgroup A polyprotein HTH_23 PF13384.1 EIE80138.1 - 0.082 12.5 0.1 0.16 11.6 0.1 1.4 1 0 0 1 1 1 0 Homeodomain-like domain AIPR PF10592.4 EIE80138.1 - 0.36 10.1 2.2 0.44 9.8 1.5 1.1 1 0 0 1 1 1 0 AIPR protein CTD_bind PF04818.8 EIE80139.1 - 1.9e-05 24.7 1.5 6e-05 23.2 1.0 1.8 1 1 0 1 1 1 1 RNA polymerase II-binding domain. CTK3 PF12243.3 EIE80139.1 - 0.00084 18.9 0.1 0.0015 18.1 0.1 1.4 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 Rad60-SLD PF11976.3 EIE80139.1 - 0.46 10.1 4.3 0.39 10.4 0.9 2.5 2 1 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like RRM_1 PF00076.17 EIE80140.1 - 2e-14 52.9 0.0 4.5e-14 51.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE80140.1 - 2.7e-11 43.2 0.0 5.2e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE80140.1 - 3.6e-06 26.7 0.0 7.3e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CRS1_YhbY PF01985.16 EIE80140.1 - 0.12 12.3 1.4 0.48 10.4 0.4 2.3 3 0 0 3 3 3 0 CRS1 / YhbY (CRM) domain Complex1_LYR_2 PF13233.1 EIE80140.1 - 1.2 9.7 4.8 0.36 11.3 0.6 1.9 1 1 1 2 2 2 0 Complex1_LYR-like PBP_sp32 PF07222.7 EIE80140.1 - 3.1 6.9 12.7 0.24 10.5 3.1 2.1 2 0 0 2 2 2 0 Proacrosin binding protein sp32 Tox-URI2 PF15653.1 EIE80140.1 - 7.9 6.7 7.9 6.1 7.1 0.1 3.1 2 1 0 3 3 3 0 URI fold toxin 2 DUF410 PF04190.8 EIE80141.1 - 1.5e-55 188.6 0.1 1.8e-55 188.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) TPR_11 PF13414.1 EIE80141.1 - 0.37 10.4 2.6 3 7.5 0.0 3.1 3 1 1 4 4 4 0 TPR repeat Ank_2 PF12796.2 EIE80142.1 - 1.6e-23 82.8 1.1 8.1e-16 58.1 0.0 3.8 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EIE80142.1 - 1e-20 73.6 10.3 1.8e-09 37.8 0.1 5.6 2 1 4 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIE80142.1 - 2.7e-16 58.0 3.9 5.3e-05 23.0 0.0 6.2 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.25 EIE80142.1 - 2.8e-15 55.2 7.2 5.8e-06 25.8 0.0 5.3 6 1 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.1 EIE80142.1 - 6.1e-14 51.7 3.2 3.4e-07 30.2 0.4 6.1 1 1 5 6 6 6 3 Ankyrin repeats (many copies) DNA_mis_repair PF01119.14 EIE80143.1 - 1.1e-08 34.4 1.7 0.00072 19.0 0.1 3.0 2 1 1 3 3 3 2 DNA mismatch repair protein, C-terminal domain DUF4106 PF13388.1 EIE80143.1 - 0.085 11.8 9.2 0.13 11.1 6.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Pex24p PF06398.6 EIE80144.1 - 1.7e-34 119.1 12.7 1.7e-34 119.1 8.8 1.6 2 0 0 2 2 2 1 Integral peroxisomal membrane peroxin DUF4112 PF13430.1 EIE80144.1 - 4.3e-11 42.6 2.4 1.8e-05 24.5 0.0 3.0 2 1 1 3 3 3 2 Domain of unknown function (DUF4112) W2 PF02020.13 EIE80144.1 - 0.002 18.0 3.4 1 9.3 0.0 3.1 3 0 0 3 3 3 2 eIF4-gamma/eIF5/eIF2-epsilon CbiQ PF02361.11 EIE80144.1 - 0.56 9.7 8.7 0.1 12.1 2.6 2.0 2 0 0 2 2 2 0 Cobalt transport protein L31 PF09784.4 EIE80144.1 - 3.4 7.7 9.2 0.11 12.5 1.4 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L31 Glyco_transf_10 PF00852.14 EIE80145.1 - 6.2e-46 156.5 0.4 1e-45 155.8 0.3 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) UPF0197 PF05251.7 EIE80146.1 - 2.6e-05 24.4 1.0 3.6e-05 23.9 0.7 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0197) DUF2910 PF11139.3 EIE80146.1 - 0.033 13.3 0.8 0.035 13.2 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2910) Cytochrom_C_asm PF01578.15 EIE80146.1 - 0.22 11.0 2.1 0.28 10.6 1.5 1.1 1 0 0 1 1 1 0 Cytochrome C assembly protein CbtB PF09489.5 EIE80146.1 - 0.93 9.4 2.7 0.63 9.9 0.7 1.6 1 1 1 2 2 2 0 Probable cobalt transporter subunit (CbtB) DUF4050 PF13259.1 EIE80147.1 - 4.5 7.2 6.7 2.5 8.0 3.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4050) Peptidase_M24 PF00557.19 EIE80148.1 - 1.3e-53 181.6 0.0 2.3e-53 180.8 0.0 1.4 2 0 0 2 2 2 1 Metallopeptidase family M24 AMP_N PF05195.11 EIE80148.1 - 0.041 13.2 0.0 0.12 11.7 0.0 1.7 2 0 0 2 2 2 0 Aminopeptidase P, N-terminal domain RRF PF01765.14 EIE80149.1 - 3.5e-50 169.6 10.5 5.4e-50 169.0 7.3 1.3 1 0 0 1 1 1 1 Ribosome recycling factor DUF883 PF05957.8 EIE80149.1 - 0.012 16.0 2.4 0.031 14.6 1.3 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Sec5 PF15469.1 EIE80149.1 - 0.016 14.9 4.8 0.016 14.9 3.3 2.1 2 1 1 3 3 3 0 Exocyst complex component Sec5 Phasin PF05597.6 EIE80149.1 - 0.13 12.0 4.1 0.31 10.7 2.8 1.6 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Muted PF14942.1 EIE80149.1 - 0.86 9.4 7.5 2.1 8.2 2.2 2.3 2 1 0 2 2 2 0 Organelle biogenesis, Muted-like protein PhoU PF01895.14 EIE80149.1 - 1.5 9.2 4.8 1.4 9.3 2.1 1.9 2 0 0 2 2 2 0 PhoU domain KMP11 PF03037.11 EIE80149.1 - 2.9 8.5 7.8 1.5 9.5 2.0 2.6 2 1 0 2 2 2 0 Kinetoplastid membrane protein 11 COBRA1 PF06209.8 EIE80150.1 - 2e-12 46.5 8.0 5.4e-06 25.2 0.1 2.9 2 1 1 3 3 3 3 Cofactor of BRCA1 (COBRA1) zf-C2H2 PF00096.21 EIE80151.1 - 2.7e-07 30.5 12.3 0.00013 22.0 1.4 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIE80151.1 - 8.4e-06 25.8 5.6 8.4e-06 25.8 3.9 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EIE80151.1 - 2.5e-05 24.2 9.7 0.024 14.9 0.7 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EIE80151.1 - 0.0031 17.3 4.6 0.0074 16.1 0.7 2.8 2 0 0 2 2 2 1 C2H2-type zinc finger Sugar_tr PF00083.19 EIE80152.1 - 3.6e-50 170.8 21.1 4.6e-50 170.5 14.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIE80152.1 - 1.3e-23 83.2 22.7 1.3e-23 83.2 15.7 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Spc97_Spc98 PF04130.8 EIE80153.1 - 7e-99 331.5 1.5 8.6e-99 331.2 1.0 1.0 1 0 0 1 1 1 1 Spc97 / Spc98 family BAAT_C PF08840.6 EIE80153.1 - 0.094 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal GLE1 PF07817.8 EIE80154.1 - 3.8e-44 150.5 1.9 3.8e-44 150.5 1.3 1.5 2 0 0 2 2 2 1 GLE1-like protein RNase_H2-Ydr279 PF09468.5 EIE80154.1 - 1.3 8.1 13.7 2.8 7.0 9.5 1.6 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Vfa1 PF08432.5 EIE80154.1 - 5.4 7.0 20.6 9.1 6.2 14.3 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 HemY_N PF07219.8 EIE80155.1 - 0.34 10.4 4.0 0.35 10.4 2.8 1.1 1 0 0 1 1 1 0 HemY protein N-terminus DUF1056 PF06341.6 EIE80155.1 - 0.53 10.3 3.3 0.61 10.1 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1056) RskA PF10099.4 EIE80155.1 - 0.77 9.4 5.0 0.67 9.6 3.5 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Thioredoxin PF00085.15 EIE80156.1 - 1.1e-47 159.9 2.3 1.8e-24 85.4 0.0 4.0 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.1 EIE80156.1 - 5.2e-25 88.3 11.2 4.6e-17 62.4 1.0 3.5 3 1 1 4 4 4 3 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EIE80156.1 - 1.6e-09 37.7 5.2 0.0037 17.3 0.0 5.1 4 1 2 6 6 6 2 Thioredoxin-like Thioredoxin_2 PF13098.1 EIE80156.1 - 5.3e-05 23.3 10.2 0.0055 16.8 0.1 5.4 4 2 0 4 4 4 1 Thioredoxin-like domain Thioredoxin_3 PF13192.1 EIE80156.1 - 6e-05 22.7 0.5 0.035 13.9 0.0 4.2 5 0 0 5 5 5 1 Thioredoxin domain Redoxin PF08534.5 EIE80156.1 - 0.00013 21.5 0.3 0.25 10.8 0.0 2.8 2 0 0 2 2 2 2 Redoxin Thioredoxin_7 PF13899.1 EIE80156.1 - 0.00024 21.0 0.9 0.053 13.5 0.0 3.3 3 0 0 3 3 3 1 Thioredoxin-like AhpC-TSA PF00578.16 EIE80156.1 - 0.0045 16.6 1.3 0.97 9.1 0.0 3.7 4 0 0 4 4 4 1 AhpC/TSA family Thioredoxin_9 PF14595.1 EIE80156.1 - 0.023 14.2 6.9 0.18 11.3 1.6 3.4 3 1 0 3 3 3 0 Thioredoxin Gp_UL130 PF11668.3 EIE80156.1 - 0.16 11.4 0.5 1 8.8 0.0 2.4 3 0 0 3 3 3 0 HCMV glycoprotein pUL130 RR_TM4-6 PF06459.7 EIE80156.1 - 1.6 8.5 22.7 2.5 7.9 15.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Nop14 PF04147.7 EIE80156.1 - 4 5.2 30.1 5.4 4.8 20.9 1.1 1 0 0 1 1 1 0 Nop14-like family Stanniocalcin PF03298.8 EIE80157.1 - 0.0076 15.2 0.1 0.0076 15.2 0.1 2.5 3 0 0 3 3 3 1 Stanniocalcin family OrfB_Zn_ribbon PF07282.6 EIE80157.1 - 0.021 14.4 0.7 0.054 13.1 0.5 1.7 1 0 0 1 1 1 0 Putative transposase DNA-binding domain DUF4298 PF14131.1 EIE80157.1 - 0.032 14.1 8.7 0.49 10.2 0.3 4.5 4 1 1 5 5 5 0 Domain of unknown function (DUF4298) 6PGD PF00393.14 EIE80158.1 - 1.6e-138 460.8 0.0 2e-138 460.5 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EIE80158.1 - 2.4e-53 180.3 0.0 3.5e-53 179.7 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EIE80158.1 - 0.00054 20.0 0.1 0.02 14.9 0.0 2.8 3 0 0 3 3 3 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 EIE80158.1 - 0.021 15.2 0.0 0.04 14.3 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ABC_membrane_2 PF06472.10 EIE80159.1 - 9.1e-67 225.1 7.2 5.8e-37 127.3 0.0 2.1 1 1 1 2 2 2 2 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EIE80159.1 - 6.5e-19 68.5 0.0 2.8e-18 66.5 0.0 2.0 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 EIE80159.1 - 4.1e-05 23.6 0.0 0.00011 22.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.14 EIE80159.1 - 0.00052 19.3 0.0 0.12 11.6 0.0 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EIE80159.1 - 0.021 14.3 0.0 0.048 13.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 EIE80159.1 - 0.024 14.9 5.5 0.027 14.7 0.1 2.9 3 1 0 4 4 4 0 AAA domain DUF258 PF03193.11 EIE80159.1 - 0.097 11.8 0.0 0.4 9.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 EIE80159.1 - 0.17 11.8 0.0 0.4 10.6 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Aminotran_3 PF00202.16 EIE80160.1 - 1.1e-112 376.2 0.0 1.3e-112 376.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EIE80160.1 - 0.00072 18.6 0.0 0.0022 17.0 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EIE80160.1 - 0.0047 16.1 0.0 0.0072 15.4 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase BORG_CEP PF14957.1 EIE80163.1 - 0.34 11.8 5.5 0.77 10.6 0.2 2.2 2 0 0 2 2 2 0 Cdc42 effector WD40 PF00400.27 EIE80165.1 - 8e-07 28.7 5.5 0.25 11.3 0.1 4.8 4 1 0 4 4 4 3 WD domain, G-beta repeat BBS2_Mid PF14783.1 EIE80165.1 - 0.009 15.7 0.0 29 4.4 0.0 3.5 2 1 1 3 3 3 2 Ciliary BBSome complex subunit 2, middle region RasGEF PF00617.14 EIE80166.1 - 1.3e-15 57.6 1.4 2.2e-15 56.8 1.0 1.4 1 0 0 1 1 1 1 RasGEF domain Bromodomain PF00439.20 EIE80167.1 - 4.9e-11 42.4 0.2 1.6e-10 40.7 0.1 1.9 1 1 0 1 1 1 1 Bromodomain Tim17 PF02466.14 EIE80168.1 - 4.8e-08 33.1 1.8 9.7e-08 32.1 1.2 1.4 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family PMP22_Claudin PF00822.15 EIE80168.1 - 0.083 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family Noc2 PF03715.8 EIE80169.1 - 2.1e-87 292.7 1.1 2.1e-87 292.7 0.8 1.8 2 0 0 2 2 2 1 Noc2p family ELO PF01151.13 EIE80171.1 - 6.5e-60 202.5 28.3 8.1e-60 202.2 19.6 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family UCN2 PF11613.3 EIE80171.1 - 9.5 6.2 6.6 22 5.0 4.6 1.6 1 0 0 1 1 1 0 Agonist of corticotropin releasing factor R2, Urocortin-2 RNase_T PF00929.19 EIE80172.1 - 1.6e-26 93.5 0.4 4.5e-26 92.0 0.0 2.0 2 0 0 2 2 2 1 Exonuclease DNA_pol_A_exo1 PF01612.15 EIE80172.1 - 0.00019 20.9 0.0 0.00061 19.3 0.0 1.9 1 1 0 1 1 1 1 3'-5' exonuclease Pkinase PF00069.20 EIE80173.1 - 8.3e-55 185.7 0.1 1.3e-54 185.1 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE80173.1 - 1e-30 106.6 0.0 1.7e-30 105.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE80173.1 - 1.2e-06 27.7 0.0 1.9e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EIE80173.1 - 0.0013 18.5 0.4 0.002 17.8 0.3 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EIE80173.1 - 0.0033 16.5 0.2 0.0055 15.7 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family AAA PF00004.24 EIE80174.1 - 7.3e-42 142.6 0.4 6.8e-40 136.3 0.0 3.2 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.8 EIE80174.1 - 3.4e-06 26.0 4.1 0.00052 18.8 0.0 2.7 2 1 1 3 3 3 2 TIP49 C-terminus AAA_17 PF13207.1 EIE80174.1 - 4.5e-05 24.2 0.2 0.00098 19.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EIE80174.1 - 5e-05 22.7 0.3 0.0035 16.7 0.0 2.9 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_22 PF13401.1 EIE80174.1 - 5.2e-05 23.4 0.1 0.0078 16.3 0.0 3.4 2 1 1 3 3 3 1 AAA domain RuvB_N PF05496.7 EIE80174.1 - 0.00013 21.1 0.0 0.00033 19.7 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EIE80174.1 - 0.00023 20.9 0.2 0.0024 17.6 0.0 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EIE80174.1 - 0.00043 20.5 0.3 0.0059 16.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EIE80174.1 - 0.00075 19.4 0.4 0.0039 17.0 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EIE80174.1 - 0.00086 19.3 0.1 0.071 13.0 0.0 3.1 2 1 0 3 3 3 1 AAA ATPase domain AAA_33 PF13671.1 EIE80174.1 - 0.0011 18.9 0.0 0.0033 17.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EIE80174.1 - 0.0014 18.5 0.8 0.0064 16.4 0.0 2.5 2 1 0 2 2 1 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.17 EIE80174.1 - 0.0019 18.3 0.3 0.013 15.6 0.0 2.8 3 0 0 3 3 2 1 RNA helicase Mg_chelatase PF01078.16 EIE80174.1 - 0.0024 17.0 0.1 0.0083 15.2 0.1 1.9 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 EIE80174.1 - 0.0027 17.1 2.2 0.15 11.4 0.2 3.4 3 1 0 4 4 4 1 AAA domain AAA_19 PF13245.1 EIE80174.1 - 0.0087 15.7 0.0 0.028 14.1 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 EIE80174.1 - 0.012 15.5 0.0 0.03 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 EIE80174.1 - 0.014 15.3 0.0 0.097 12.7 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain Zeta_toxin PF06414.7 EIE80174.1 - 0.024 13.7 0.0 0.065 12.3 0.0 1.8 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.7 EIE80174.1 - 0.027 14.1 1.9 0.19 11.3 0.0 3.1 3 2 1 4 4 3 0 NACHT domain ATP-synt_ab PF00006.20 EIE80174.1 - 0.041 13.3 0.0 0.092 12.2 0.0 1.6 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AcetylCoA_hydro PF02550.10 EIE80175.1 - 1.5e-51 175.0 0.0 2.1e-51 174.5 0.0 1.2 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.1 EIE80175.1 - 1.1e-38 132.3 0.0 1.6e-38 131.8 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain CoA_trans PF01144.18 EIE80175.1 - 0.051 12.7 0.0 0.12 11.5 0.0 1.6 2 0 0 2 2 2 0 Coenzyme A transferase AA_permease_2 PF13520.1 EIE80176.1 - 9.8e-43 146.2 33.4 1.1e-42 146.0 23.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EIE80176.1 - 1.3e-21 76.4 28.4 1.7e-21 76.1 19.7 1.0 1 0 0 1 1 1 1 Amino acid permease DUF3461 PF11944.3 EIE80177.1 - 0.022 14.5 1.9 0.054 13.3 0.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3461) TACC PF05010.9 EIE80177.1 - 0.024 14.4 1.3 0.033 13.9 0.9 1.3 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) BLOC1_2 PF10046.4 EIE80177.1 - 0.03 14.4 2.5 0.3 11.2 0.3 2.9 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Muted PF14942.1 EIE80177.1 - 0.089 12.6 1.2 0.28 11.0 0.3 1.9 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein Nnf1 PF03980.9 EIE80177.1 - 0.12 12.3 3.5 0.37 10.8 0.7 2.3 2 0 0 2 2 2 0 Nnf1 Mannitol_dh PF01232.18 EIE80177.1 - 0.14 12.1 0.4 0.24 11.3 0.3 1.4 1 0 0 1 1 1 0 Mannitol dehydrogenase Rossmann domain Rotamase PF00639.16 EIE80177.1 - 0.18 12.5 1.2 0.58 10.9 0.8 1.9 1 1 0 1 1 1 0 PPIC-type PPIASE domain 3-dmu-9_3-mt PF06983.8 EIE80177.1 - 0.34 11.2 3.0 7.2 6.9 0.2 2.4 2 0 0 2 2 2 0 3-demethylubiquinone-9 3-methyltransferase IncA PF04156.9 EIE80177.1 - 0.71 9.4 3.8 2.1 7.9 2.6 1.8 1 1 0 1 1 1 0 IncA protein Beta_helix PF13229.1 EIE80178.1 - 1.3e-07 31.4 16.4 2e-05 24.3 2.0 2.7 2 0 0 2 2 2 2 Right handed beta helix region Pectate_lyase_3 PF12708.2 EIE80178.1 - 1.2e-05 25.5 14.1 0.0012 18.9 9.7 3.1 1 1 0 1 1 1 1 Pectate lyase superfamily protein Ku_N PF03731.10 EIE80179.1 - 7.5e-37 126.9 0.3 7.5e-37 126.9 0.2 1.7 2 0 0 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain Ku PF02735.11 EIE80179.1 - 4.5e-17 62.1 0.0 9e-17 61.1 0.0 1.5 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ish1 PF10281.4 EIE80179.1 - 0.0083 16.1 0.1 0.021 14.9 0.1 1.7 1 0 0 1 1 1 1 Putative stress-responsive nuclear envelope protein SAP PF02037.22 EIE80179.1 - 0.088 12.3 0.1 0.15 11.5 0.1 1.4 1 0 0 1 1 1 0 SAP domain VWA_2 PF13519.1 EIE80179.1 - 0.11 12.5 0.0 0.43 10.6 0.0 1.8 1 1 0 1 1 1 0 von Willebrand factor type A domain Arrestin_N PF00339.24 EIE80180.1 - 8.3e-16 58.1 0.0 3.1e-15 56.2 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EIE80180.1 - 6.5e-07 29.5 0.0 0.00014 21.9 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.2 EIE80180.1 - 0.021 14.2 0.0 0.054 12.9 0.0 1.7 1 1 0 1 1 1 0 Arrestin_N terminal like Melibiase PF02065.13 EIE80181.1 - 5.2e-21 74.7 0.3 7.2e-21 74.3 0.2 1.1 1 0 0 1 1 1 1 Melibiase Glyco_hydro_31 PF01055.21 EIE80181.1 - 1.9e-11 43.4 0.1 2.9e-11 42.8 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 GHL6 PF14871.1 EIE80181.1 - 0.0015 18.5 0.0 0.11 12.5 0.0 2.4 2 0 0 2 2 2 1 Hypothetical glycosyl hydrolase 6 Raffinose_syn PF05691.7 EIE80181.1 - 0.04 11.4 0.2 0.06 10.8 0.1 1.2 1 0 0 1 1 1 0 Raffinose synthase or seed imbibition protein Sip1 Suf PF05843.9 EIE80182.1 - 1.1e-06 28.6 0.8 0.0024 17.6 0.0 2.7 3 1 0 3 3 3 2 Suppressor of forked protein (Suf) TPR_14 PF13428.1 EIE80182.1 - 0.0033 17.9 0.2 5.3 7.9 0.1 4.5 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.1 EIE80182.1 - 0.05 13.2 0.4 0.25 11.0 0.1 2.4 3 0 0 3 3 3 0 TPR repeat PepSY PF03413.14 EIE80182.1 - 0.076 13.6 0.2 2.7 8.6 0.1 2.7 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain TPR_16 PF13432.1 EIE80182.1 - 0.36 11.5 5.9 30 5.4 1.2 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 EIE80182.1 - 1.7 8.7 6.3 16 5.6 0.6 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Polysacc_deac_1 PF01522.16 EIE80185.1 - 2.1e-26 91.9 0.0 3.3e-26 91.3 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 EIE80185.1 - 2.4e-05 23.4 0.0 4.7e-05 22.4 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 57 Polysacc_deac_1 PF01522.16 EIE80186.1 - 2.3e-25 88.5 0.0 3.6e-25 87.9 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 EIE80186.1 - 1.4e-05 24.1 0.0 2.3e-05 23.4 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 57 CemA PF03040.9 EIE80189.1 - 0.00071 19.2 0.6 0.0009 18.9 0.4 1.1 1 0 0 1 1 1 1 CemA family Dynamin_N PF00350.18 EIE80191.1 - 1.9e-17 63.6 0.6 2.1e-16 60.1 0.0 2.9 2 2 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 EIE80191.1 - 1.6e-09 37.7 0.7 1.3e-08 34.7 0.1 2.9 2 2 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EIE80191.1 - 2.7e-07 30.2 1.1 1.2e-05 24.8 0.7 2.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Miro PF08477.8 EIE80191.1 - 0.0017 18.8 0.0 0.13 12.7 0.0 2.9 2 0 0 2 2 2 1 Miro-like protein AAA_29 PF13555.1 EIE80191.1 - 0.003 17.0 0.0 0.007 15.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SRPRB PF09439.5 EIE80191.1 - 0.01 15.0 1.5 2.2 7.4 0.1 3.8 4 0 0 4 4 4 0 Signal recognition particle receptor beta subunit AAA_25 PF13481.1 EIE80191.1 - 0.018 14.4 0.2 0.35 10.2 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.1 EIE80191.1 - 0.041 13.8 0.7 1.5 8.7 0.0 3.3 3 0 0 3 3 3 0 AAA ATPase domain FtsK_SpoIIIE PF01580.13 EIE80191.1 - 0.041 13.3 0.1 0.13 11.7 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family Ribosomal_S27e PF01667.12 EIE80192.1 - 7.3e-26 89.4 5.1 7.8e-26 89.3 3.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S27 TF_Zn_Ribbon PF08271.7 EIE80192.1 - 0.00031 19.9 2.5 0.00039 19.6 1.7 1.2 1 0 0 1 1 1 1 TFIIB zinc-binding IBR PF01485.16 EIE80192.1 - 0.0076 16.1 2.3 0.008 16.0 1.6 1.2 1 0 0 1 1 1 1 IBR domain zf-ribbon_3 PF13248.1 EIE80192.1 - 0.032 13.4 2.4 1.5 8.1 0.3 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2HC5 PF06221.8 EIE80192.1 - 0.034 13.9 1.1 0.034 13.9 0.8 1.6 1 1 1 2 2 2 0 Putative zinc finger motif, C2HC5-type zinc_ribbon_4 PF13717.1 EIE80192.1 - 0.061 13.0 2.6 3.2 7.5 1.8 2.4 1 1 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EIE80192.1 - 0.091 12.3 2.8 5 6.7 1.9 2.4 1 1 0 1 1 1 0 zinc-ribbon domain PhnA_Zn_Ribbon PF08274.7 EIE80192.1 - 0.11 12.2 0.6 0.22 11.3 0.4 1.4 1 0 0 1 1 1 0 PhnA Zinc-Ribbon TFIIS_C PF01096.13 EIE80192.1 - 0.2 11.3 1.9 1.1 8.9 0.0 2.2 1 1 1 2 2 2 0 Transcription factor S-II (TFIIS) FYVE PF01363.16 EIE80192.1 - 0.22 11.4 3.1 0.22 11.4 2.2 1.1 1 0 0 1 1 1 0 FYVE zinc finger RecR PF02132.10 EIE80192.1 - 0.27 10.6 3.8 1.2 8.6 0.6 2.2 2 0 0 2 2 2 0 RecR protein Prok-RING_1 PF14446.1 EIE80192.1 - 0.28 10.9 3.0 0.36 10.5 2.1 1.4 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 OrfB_Zn_ribbon PF07282.6 EIE80192.1 - 0.49 10.0 2.7 0.57 9.8 1.9 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Auto_anti-p27 PF06677.7 EIE80192.1 - 0.5 10.1 0.2 0.5 10.1 0.2 2.0 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-NADH-PPase PF09297.6 EIE80192.1 - 1 8.9 0.1 1 8.9 0.0 2.4 2 1 1 3 3 3 0 NADH pyrophosphatase zinc ribbon domain Zn_Tnp_IS1 PF03811.8 EIE80192.1 - 1.3 8.6 4.0 7.3 6.1 2.8 2.1 1 1 0 1 1 1 0 InsA N-terminal domain UPF0547 PF10571.4 EIE80192.1 - 1.7 8.3 4.2 4.9 6.9 0.2 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-LSD1 PF06943.7 EIE80192.1 - 1.8 8.2 5.7 2.9 7.5 1.6 2.3 2 0 0 2 2 2 0 LSD1 zinc finger Tnp_zf-ribbon_2 PF13842.1 EIE80192.1 - 1.9 8.9 6.2 0.45 10.9 1.9 1.8 2 1 0 2 2 1 0 DDE_Tnp_1-like zinc-ribbon zf-C3HC4_3 PF13920.1 EIE80192.1 - 2 8.1 5.4 3.7 7.3 3.7 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DZR PF12773.2 EIE80192.1 - 2.2 8.1 5.0 9.1 6.1 3.5 2.0 1 1 0 1 1 1 0 Double zinc ribbon Acyltransferase PF01553.16 EIE80193.1 - 3.5e-12 45.8 0.0 6.1e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase FA_desaturase PF00487.19 EIE80193.1 - 0.072 12.5 1.8 0.11 11.9 1.3 1.2 1 0 0 1 1 1 0 Fatty acid desaturase Dynamin_M PF01031.15 EIE80194.1 - 2.8e-107 357.9 1.6 5.1e-107 357.0 0.0 2.0 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 EIE80194.1 - 1.4e-55 187.6 0.0 2.9e-55 186.6 0.0 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 EIE80194.1 - 4.6e-31 106.5 6.2 1.1e-30 105.3 4.3 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EIE80194.1 - 0.00063 19.6 1.1 0.0032 17.4 0.1 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase Taeniidae_ag PF05596.6 EIE80194.1 - 0.011 15.5 0.7 7.1 6.5 0.0 3.3 3 0 0 3 3 3 0 Taeniidae antigen Miro PF08477.8 EIE80194.1 - 0.027 14.9 0.0 0.084 13.3 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein DUF2019 PF09450.5 EIE80196.1 - 0.052 13.4 0.2 0.09 12.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2019) Mito_carr PF00153.22 EIE80197.1 - 1.3e-47 159.4 9.1 7.2e-18 64.0 0.4 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Mur_ligase_M PF08245.7 EIE80198.1 - 3e-07 30.6 0.7 8.3e-06 25.9 0.5 2.9 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.16 EIE80198.1 - 0.0026 17.7 0.0 0.0077 16.2 0.0 1.8 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain KilA-N PF04383.8 EIE80199.1 - 0.00012 21.7 0.1 0.0017 17.9 0.0 2.1 1 1 0 1 1 1 1 KilA-N domain MIT PF04212.13 EIE80200.1 - 2.1e-09 37.0 0.4 4.8e-09 35.9 0.3 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain DUF3543 PF12063.3 EIE80200.1 - 0.015 14.5 0.4 0.038 13.2 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3543) SLA_LP_auto_ag PF05889.8 EIE80200.1 - 0.084 11.3 0.1 0.14 10.6 0.1 1.3 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) DDE_3 PF13358.1 EIE80201.1 - 1.8e-18 66.6 0.0 2.1e-18 66.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE80201.1 - 0.035 14.2 0.0 0.043 13.9 0.0 1.2 1 0 0 1 1 1 0 Integrase core domain DDE_Tnp_ISAZ013 PF07592.6 EIE80201.1 - 0.12 11.1 0.1 0.15 10.7 0.1 1.1 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain Galactosyl_T PF01762.16 EIE80202.1 - 3.1e-20 72.6 0.0 6.2e-20 71.6 0.0 1.5 1 0 0 1 1 1 1 Galactosyltransferase Gly_transf_sug PF04488.10 EIE80202.1 - 9.2e-10 38.8 0.2 4e-09 36.7 0.1 2.2 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif EOS1 PF12326.3 EIE80202.1 - 2.1e-08 33.9 10.5 4.2e-08 32.9 7.3 1.5 1 0 0 1 1 1 1 N-glycosylation protein Gb3_synth PF04572.7 EIE80202.1 - 1.2e-05 25.0 0.0 2.4e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Alpha 1,4-glycosyltransferase conserved region Caps_synth PF05704.7 EIE80202.1 - 0.0019 17.3 0.1 0.004 16.3 0.1 1.4 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Cys_Met_Meta_PP PF01053.15 EIE80203.1 - 9.4e-134 445.5 0.0 1.1e-133 445.3 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EIE80203.1 - 2.3e-06 26.5 0.0 3.2e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EIE80203.1 - 1.8e-05 23.8 0.0 2.6e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Met_gamma_lyase PF06838.6 EIE80203.1 - 0.00027 19.3 0.0 0.0018 16.6 0.0 1.9 1 1 0 1 1 1 1 Methionine gamma-lyase SelA PF03841.8 EIE80203.1 - 0.013 14.2 0.0 0.043 12.5 0.0 1.7 1 1 0 1 1 1 0 L-seryl-tRNA selenium transferase Beta_elim_lyase PF01212.16 EIE80203.1 - 0.04 13.0 0.0 0.07 12.2 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase Daxx PF03344.10 EIE80205.1 - 0.00026 19.6 7.8 0.00026 19.6 5.4 2.3 2 0 0 2 2 2 1 Daxx Family CDC45 PF02724.9 EIE80205.1 - 0.0031 15.6 12.2 0.0046 15.0 8.5 1.2 1 0 0 1 1 1 1 CDC45-like protein Pkinase PF00069.20 EIE80206.1 - 9.4e-69 231.4 0.0 1.7e-68 230.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE80206.1 - 3.6e-51 173.7 0.0 6e-51 172.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE80206.1 - 2.1e-05 23.6 0.0 7.7e-05 21.7 0.0 1.9 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 EIE80206.1 - 0.009 15.3 0.1 0.021 14.1 0.1 1.7 1 0 0 1 1 1 1 RIO1 family CH PF00307.26 EIE80206.1 - 0.024 14.6 0.0 0.087 12.8 0.0 2.0 1 0 0 1 1 1 0 Calponin homology (CH) domain V-ATPase_C PF03223.10 EIE80207.1 - 1.1e-116 389.8 9.9 1.2e-116 389.6 6.9 1.0 1 0 0 1 1 1 1 V-ATPase subunit C mRNA_cap_C PF03919.10 EIE80207.1 - 0.035 14.4 0.7 0.12 12.7 0.5 2.0 1 1 0 1 1 1 0 mRNA capping enzyme, C-terminal domain DUF3936 PF13072.1 EIE80207.1 - 0.24 10.8 1.8 15 5.1 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3936) ABC2_membrane_3 PF12698.2 EIE80207.1 - 0.68 8.9 4.1 1 8.3 2.8 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein H-kinase_dim PF02895.9 EIE80207.1 - 0.89 9.9 5.3 0.94 9.8 0.7 2.8 2 1 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain Fib_alpha PF08702.5 EIE80207.1 - 8.5 6.4 9.0 48 4.0 2.9 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family p450 PF00067.17 EIE80208.1 - 2e-54 184.8 0.0 2.5e-54 184.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Myc_N PF01056.13 EIE80212.1 - 0.086 11.9 1.8 0.11 11.6 1.3 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Nucleo_P87 PF07267.6 EIE80213.1 - 0.085 11.5 0.1 0.088 11.4 0.1 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Meth_synt_2 PF01717.13 EIE80214.1 - 3.9e-153 509.1 0.0 7.3e-139 462.2 0.0 3.0 3 0 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EIE80214.1 - 1.4e-121 405.5 0.0 9.1e-108 360.1 0.2 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain RhoGAP PF00620.22 EIE80215.1 - 1.3e-13 50.8 0.2 9.8e-13 47.9 0.0 2.3 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.18 EIE80215.1 - 4.1e-13 49.3 1.9 1.6e-12 47.4 0.1 3.0 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain DEP PF00610.16 EIE80215.1 - 2.4e-08 33.5 0.0 7.9e-08 31.9 0.0 2.0 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) EF-hand_4 PF12763.2 EIE80216.1 - 0.08 12.6 0.1 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand DUF4613 PF15390.1 EIE80216.1 - 0.14 10.2 2.8 0.2 9.8 2.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) WD40 PF00400.27 EIE80218.1 - 3.7e-38 128.0 15.6 1.9e-06 27.4 0.2 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 EIE80218.1 - 7.7e-06 24.3 6.3 0.22 9.6 0.5 4.4 1 1 2 4 4 4 3 Nucleoporin Nup120/160 PQQ_3 PF13570.1 EIE80218.1 - 1.8e-05 24.8 0.0 3 8.2 0.0 5.0 5 1 1 6 6 6 2 PQQ-like domain PQQ_2 PF13360.1 EIE80218.1 - 0.00012 21.6 1.6 0.26 10.6 0.1 3.3 2 1 1 3 3 3 2 PQQ-like domain SGL PF08450.7 EIE80218.1 - 0.0015 18.0 0.6 0.074 12.4 0.1 2.6 2 1 0 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region Nucleoporin_N PF08801.6 EIE80218.1 - 0.0017 17.2 5.7 0.13 10.9 1.8 4.1 1 1 4 5 5 5 1 Nup133 N terminal like Reg_prop PF07494.6 EIE80218.1 - 0.018 14.9 0.2 0.98 9.6 0.2 3.0 2 0 0 2 2 2 0 Two component regulator propeller Abhydrolase_1 PF00561.15 EIE80218.1 - 0.044 13.3 0.0 2.7 7.4 0.0 2.3 2 0 0 2 2 2 0 alpha/beta hydrolase fold Urease_alpha PF00449.15 EIE80218.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Urease alpha-subunit, N-terminal domain UAA PF08449.6 EIE80219.1 - 0.0058 15.5 1.1 0.0098 14.8 0.7 1.4 1 0 0 1 1 1 1 UAA transporter family MFS_1 PF07690.11 EIE80221.1 - 5.6e-22 77.9 53.5 2.5e-11 42.9 14.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EIE80221.1 - 0.0033 15.8 8.3 0.0033 15.8 5.7 3.8 1 1 2 4 4 4 3 MFS/sugar transport protein FF PF01846.14 EIE80222.1 - 7.9e-40 134.5 10.4 9e-12 44.7 0.0 5.9 5 0 0 5 5 5 5 FF domain FKS1_dom1 PF14288.1 EIE80222.1 - 0.036 13.9 0.4 0.036 13.9 0.2 2.8 4 0 0 4 4 4 0 1,3-beta-glucan synthase subunit FKS1, domain-1 E1-E2_ATPase PF00122.15 EIE80223.1 - 7.1e-61 205.1 3.1 7.1e-61 205.1 2.1 2.3 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EIE80223.1 - 1.4e-44 151.8 11.8 1.4e-44 151.8 8.2 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EIE80223.1 - 4.6e-26 92.5 0.6 8.7e-26 91.6 0.4 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EIE80223.1 - 2.1e-19 69.2 1.1 5.1e-19 68.0 0.2 2.1 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EIE80223.1 - 7.7e-15 55.5 0.0 2.3e-14 54.0 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EIE80223.1 - 1.3e-14 53.3 0.0 3e-14 52.2 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EIE80223.1 - 0.0013 18.3 0.5 0.0013 18.3 0.4 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase NIF PF03031.13 EIE80224.1 - 3e-22 78.9 2.6 5e-22 78.2 0.1 2.3 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase BRCT PF00533.21 EIE80224.1 - 1.7e-08 34.4 0.4 1.5e-07 31.4 0.0 2.5 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EIE80224.1 - 1e-06 28.4 1.0 3.2e-06 26.9 0.7 1.8 1 0 0 1 1 1 1 twin BRCT domain RskA PF10099.4 EIE80225.1 - 0.0031 17.2 0.2 0.0053 16.5 0.2 1.4 1 0 0 1 1 1 1 Anti-sigma-K factor rskA Drc1-Sld2 PF11719.3 EIE80225.1 - 0.02 14.0 29.5 0.025 13.6 20.4 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein Chorion_2 PF03964.10 EIE80225.1 - 0.046 14.2 0.7 0.074 13.5 0.5 1.4 1 0 0 1 1 1 0 Chorion family 2 DivIC PF04977.10 EIE80225.1 - 0.46 10.0 0.1 0.46 10.0 0.1 3.7 2 1 1 3 3 2 0 Septum formation initiator MIP-T3 PF10243.4 EIE80225.1 - 1 7.7 40.1 1.2 7.4 27.8 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CRT10 PF08728.5 EIE80225.1 - 1.1 7.0 11.5 1.3 6.9 8.0 1.1 1 0 0 1 1 1 0 CRT10 IgaA PF07095.6 EIE80225.1 - 1.4 6.5 4.0 1.3 6.7 1.9 1.4 1 1 1 2 2 2 0 Intracellular growth attenuator protein IgaA Exonuc_VII_L PF02601.10 EIE80225.1 - 3.2 6.8 20.3 4.3 6.4 14.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Asp-B-Hydro_N PF05279.6 EIE80225.1 - 4.7 6.9 23.4 6.4 6.5 16.2 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF2031 PF09592.5 EIE80225.1 - 6.3 5.8 21.2 11 5.0 14.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) APG6 PF04111.7 EIE80225.1 - 6.4 5.7 24.1 9.9 5.1 16.7 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Prefoldin_2 PF01920.15 EIE80226.1 - 1.5e-21 76.1 16.6 2e-21 75.7 11.5 1.2 1 0 0 1 1 1 1 Prefoldin subunit DMPK_coil PF08826.5 EIE80226.1 - 0.00031 20.5 6.6 0.00031 20.5 4.6 2.2 2 0 0 2 2 2 1 DMPK coiled coil domain like DUF4201 PF13870.1 EIE80226.1 - 0.012 15.0 13.8 0.33 10.3 3.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) DUF3727 PF12527.3 EIE80226.1 - 0.02 14.9 2.5 0.027 14.5 1.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3727) Prefoldin_3 PF13758.1 EIE80226.1 - 0.045 13.5 8.6 0.043 13.5 5.1 1.6 1 1 0 1 1 1 0 Prefoldin subunit GAS PF13851.1 EIE80226.1 - 0.055 12.6 19.8 0.17 11.0 13.7 1.7 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Occludin_ELL PF07303.8 EIE80226.1 - 0.066 13.9 9.8 0.63 10.8 1.5 2.2 2 0 0 2 2 2 0 Occludin homology domain DUF1664 PF07889.7 EIE80226.1 - 0.068 12.9 8.6 1 9.1 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) T2SJ PF11612.3 EIE80226.1 - 0.069 12.8 1.2 0.11 12.1 0.6 1.5 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein J EzrA PF06160.7 EIE80226.1 - 0.078 11.1 16.7 0.14 10.3 7.0 2.0 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA DUF4140 PF13600.1 EIE80226.1 - 0.14 12.5 6.7 3.7 8.0 0.4 2.4 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Prefoldin PF02996.12 EIE80226.1 - 0.15 11.7 15.0 2.4 7.8 10.4 2.2 1 1 0 1 1 1 0 Prefoldin subunit DUF489 PF04356.7 EIE80226.1 - 0.17 11.4 7.8 0.23 11.0 0.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF489) IZUMO PF15005.1 EIE80226.1 - 0.19 11.7 7.1 0.22 11.5 4.9 1.1 1 0 0 1 1 1 0 Izumo sperm-egg fusion DUF972 PF06156.8 EIE80226.1 - 0.32 11.3 15.2 1.6 9.1 2.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF972) IncA PF04156.9 EIE80226.1 - 0.36 10.3 20.6 1.1 8.7 14.3 1.7 1 1 0 1 1 1 0 IncA protein NPV_P10 PF05531.7 EIE80226.1 - 0.39 11.0 6.5 5.2 7.3 0.4 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF1192 PF06698.6 EIE80226.1 - 0.47 10.2 7.6 0.28 11.0 0.3 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) Atg14 PF10186.4 EIE80226.1 - 0.5 9.2 11.8 0.54 9.1 8.2 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF948 PF06103.6 EIE80226.1 - 0.56 10.1 9.9 0.33 10.8 1.3 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) End3 PF12761.2 EIE80226.1 - 0.59 9.7 12.8 1.1 8.8 8.8 1.4 1 1 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 PMC2NT PF08066.7 EIE80226.1 - 0.68 10.2 3.5 0.68 10.2 0.9 1.9 1 1 2 3 3 3 0 PMC2NT (NUC016) domain DivIC PF04977.10 EIE80226.1 - 0.73 9.3 16.4 1.3 8.5 2.8 2.5 2 1 1 3 3 3 0 Septum formation initiator DUF1374 PF07118.6 EIE80226.1 - 0.86 9.7 8.7 0.35 10.9 1.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1374) Phage_GP20 PF06810.6 EIE80226.1 - 1.2 8.6 14.4 1 8.7 3.3 2.1 2 0 0 2 2 2 0 Phage minor structural protein GP20 FlxA PF14282.1 EIE80226.1 - 1.6 8.6 15.1 0.94 9.4 2.5 2.1 2 0 0 2 2 2 0 FlxA-like protein Sec8_exocyst PF04048.9 EIE80226.1 - 2 8.0 10.8 8.1 6.0 5.1 2.1 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain DUF3166 PF11365.3 EIE80226.1 - 2.1 8.8 11.4 0.43 11.0 1.6 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3166) Spc7 PF08317.6 EIE80226.1 - 2.1 6.9 16.8 3.7 6.1 11.6 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein APG6 PF04111.7 EIE80226.1 - 9.3 5.1 19.0 0.53 9.2 5.5 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 rve PF00665.21 EIE80228.1 - 1.7e-24 86.1 0.0 5.6e-24 84.5 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE80228.1 - 6.8e-17 61.5 0.0 1.3e-16 60.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE80228.1 - 3.7e-10 39.3 0.6 1.1e-09 37.8 0.4 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 EIE80228.1 - 0.00038 19.7 0.1 0.001 18.4 0.1 1.8 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger UBN2_2 PF14227.1 EIE80228.1 - 0.017 14.6 1.1 0.33 10.5 0.0 2.8 3 0 0 3 3 3 0 gag-polypeptide of LTR copia-type rve_3 PF13683.1 EIE80228.1 - 0.026 14.0 0.0 0.086 12.3 0.0 2.0 1 0 0 1 1 1 0 Integrase core domain UBN2 PF14223.1 EIE80228.1 - 0.062 13.0 0.6 0.16 11.7 0.1 1.9 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type DUF619 PF04768.8 EIE80230.1 - 5.1e-39 133.4 0.3 9.6e-39 132.5 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF619) Semialdhyde_dh PF01118.19 EIE80230.1 - 6e-29 100.8 0.0 1.5e-28 99.5 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.23 EIE80230.1 - 2.3e-24 86.3 0.0 4.3e-24 85.3 0.0 1.4 1 0 0 1 1 1 1 Amino acid kinase family Semialdhyde_dhC PF02774.13 EIE80230.1 - 7.2e-08 32.5 0.0 1.6e-07 31.3 0.0 1.6 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain DapB_N PF01113.15 EIE80230.1 - 0.035 14.0 0.0 0.11 12.4 0.0 1.9 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus COX7C PF02935.11 EIE80231.1 - 3.9e-15 55.4 0.0 4.1e-15 55.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc DnaJ PF00226.26 EIE80233.1 - 2.5e-08 33.5 0.5 6.7e-08 32.1 0.4 1.7 1 0 0 1 1 1 1 DnaJ domain DUF1436 PF07262.6 EIE80233.1 - 0.0088 15.5 0.2 0.015 14.7 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1436) BSMAP PF12280.3 EIE80233.1 - 0.29 11.0 3.0 0.44 10.4 2.1 1.3 1 0 0 1 1 1 0 Brain specific membrane anchored protein BORG_CEP PF14957.1 EIE80233.1 - 1.1 10.2 6.6 3.8 8.4 1.6 2.2 2 1 0 2 2 2 0 Cdc42 effector Glyco_hydro_45 PF02015.11 EIE80234.1 - 3.2e-86 288.5 22.7 3.2e-86 288.5 15.7 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 45 CBM_1 PF00734.13 EIE80234.1 - 5.5e-14 51.5 11.6 5.5e-14 51.5 8.1 2.6 2 0 0 2 2 2 1 Fungal cellulose binding domain MAP65_ASE1 PF03999.7 EIE80234.1 - 2.9 6.3 8.5 3.7 6.0 5.9 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) MSP1_C PF07462.6 EIE80234.1 - 6.3 5.0 6.4 8.6 4.6 4.4 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Grp1_Fun34_YaaH PF01184.14 EIE80236.1 - 2e-31 108.9 21.3 2.3e-31 108.7 14.8 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Phosphodiest PF01663.17 EIE80237.1 - 3.5e-12 46.3 0.0 5.5e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Phosphodiest PF01663.17 EIE80238.1 - 9.6e-09 35.0 0.6 1.2e-08 34.7 0.4 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Adeno_PV PF03910.8 EIE80239.1 - 0.089 11.8 0.0 0.1 11.6 0.0 1.0 1 0 0 1 1 1 0 Adenovirus minor core protein PV DUF2217 PF10265.4 EIE80241.1 - 0.015 14.0 1.2 0.019 13.7 0.8 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DUF1762 PF08574.5 EIE80241.1 - 6.6 7.2 10.5 7 7.1 2.3 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1762) Solute_trans_a PF03619.11 EIE80242.1 - 1.6e-54 185.1 7.1 2e-54 184.7 4.9 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha BUD22 PF09073.5 EIE80243.1 - 0.0048 16.0 35.5 0.0061 15.6 24.6 1.1 1 0 0 1 1 1 1 BUD22 COX5B PF01215.14 EIE80244.1 - 2.6e-37 127.5 0.0 3.1e-37 127.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-C4_Topoisom PF01396.14 EIE80244.1 - 0.0052 16.2 0.7 0.55 9.7 0.0 2.2 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zf-CHCC PF10276.4 EIE80244.1 - 0.0071 16.1 0.3 0.011 15.5 0.2 1.3 1 0 0 1 1 1 1 Zinc-finger domain COG6 PF06419.6 EIE80244.1 - 0.14 10.3 0.0 0.17 9.9 0.0 1.1 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 NDUFA12 PF05071.11 EIE80245.1 - 1.4e-21 76.9 1.4 1.4e-21 76.9 1.0 1.6 1 1 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Sds3 PF08598.6 EIE80246.1 - 3e-07 30.1 15.4 3.4e-07 30.0 10.7 1.1 1 0 0 1 1 1 1 Sds3-like DUF2115 PF09888.4 EIE80246.1 - 0.14 12.2 5.1 0.19 11.7 3.5 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) SMN PF06003.7 EIE80247.1 - 3.3e-06 26.3 3.5 4.3e-06 26.0 2.4 1.1 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) DUF4537 PF15057.1 EIE80247.1 - 0.00074 19.2 0.0 0.0013 18.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) LBR_tudor PF09465.5 EIE80247.1 - 0.00079 19.0 0.0 0.0013 18.3 0.0 1.4 1 0 0 1 1 1 1 Lamin-B receptor of TUDOR domain DUF1325 PF07039.6 EIE80247.1 - 0.0015 18.1 0.1 0.0049 16.4 0.1 1.9 1 1 0 1 1 1 1 SGF29 tudor-like domain TUDOR PF00567.19 EIE80247.1 - 0.0055 16.5 0.1 0.041 13.7 0.0 2.1 1 1 1 2 2 2 1 Tudor domain 53-BP1_Tudor PF09038.5 EIE80247.1 - 0.051 13.4 0.0 0.076 12.8 0.0 1.3 1 0 0 1 1 1 0 Tumour suppressor p53-binding protein-1 Tudor Mito_carr PF00153.22 EIE80248.1 - 6.6e-16 57.8 0.0 7.7e-16 57.5 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial carrier protein CAF1 PF04857.15 EIE80249.1 - 3e-52 177.5 2.6 4.6e-52 176.9 1.8 1.3 1 0 0 1 1 1 1 CAF1 family ribonuclease Mito_carr PF00153.22 EIE80249.1 - 1.2e-30 105.0 0.1 3.7e-19 68.2 0.0 2.4 2 0 0 2 2 2 2 Mitochondrial carrier protein ThylakoidFormat PF11264.3 EIE80249.1 - 0.0088 15.6 0.5 0.018 14.6 0.3 1.4 1 0 0 1 1 1 1 Thylakoid formation protein Ank_2 PF12796.2 EIE80250.1 - 2.9e-155 505.0 61.2 4.5e-21 74.9 0.0 18.1 6 4 13 20 20 20 20 Ankyrin repeats (3 copies) Ank PF00023.25 EIE80250.1 - 8.5e-108 347.2 44.5 1.1e-08 34.4 0.3 29.1 29 2 1 30 30 30 20 Ankyrin repeat Ank_4 PF13637.1 EIE80250.1 - 7.2e-105 341.7 42.2 8.4e-12 45.2 0.2 24.2 15 6 10 25 25 25 18 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIE80250.1 - 1.8e-81 259.8 39.2 0.00045 20.1 0.0 29.2 29 0 0 29 29 29 16 Ankyrin repeat Ank_5 PF13857.1 EIE80250.1 - 7.1e-81 264.4 39.1 8.2e-08 32.2 0.3 23.1 13 3 10 23 23 23 17 Ankyrin repeats (many copies) PARP PF00644.15 EIE80250.1 - 9.8e-50 168.8 0.1 2.5e-49 167.5 0.1 1.8 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain WGR PF05406.10 EIE80250.1 - 6.3e-13 48.4 0.0 2.1e-12 46.8 0.0 2.0 1 0 0 1 1 1 1 WGR domain NDK PF00334.14 EIE80251.1 - 7.4e-28 97.0 0.1 1.5e-27 96.0 0.1 1.5 1 0 0 1 1 1 1 Nucleoside diphosphate kinase p450 PF00067.17 EIE80252.1 - 7.5e-62 209.3 0.0 1e-61 208.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Aminotran_4 PF01063.14 EIE80253.1 - 5.9e-24 84.8 0.0 7.1e-24 84.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV DAGAT PF03982.8 EIE80254.1 - 5.9e-85 284.5 0.0 7.5e-85 284.2 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase CIAPIN1 PF05093.8 EIE80255.1 - 2e-28 98.3 4.5 4.7e-28 97.2 3.1 1.6 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Pantoate_transf PF02548.10 EIE80256.1 - 2.7e-95 318.4 0.3 3.1e-95 318.2 0.2 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 EIE80256.1 - 5.9e-06 25.6 0.2 1.8e-05 24.1 0.1 1.9 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Poxvirus_B22R_C PF13168.1 EIE80256.1 - 0.11 11.7 0.2 0.17 11.1 0.1 1.2 1 0 0 1 1 1 0 Poxvirus B22R protein C-terminal zf-C3HC4_2 PF13923.1 EIE80257.1 - 2.3e-08 33.9 10.6 4e-08 33.1 7.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EIE80257.1 - 4.4e-08 32.6 5.9 7.2e-08 31.9 4.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH PF00642.19 EIE80257.1 - 1.8e-07 30.6 1.3 4e-07 29.5 0.9 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_2 PF13639.1 EIE80257.1 - 1.4e-06 28.0 7.7 2.3e-06 27.3 5.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EIE80257.1 - 5.4e-06 26.0 9.6 9.6e-06 25.2 6.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EIE80257.1 - 1e-05 25.0 11.3 1.9e-05 24.1 7.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EIE80257.1 - 0.00083 19.1 9.0 0.002 17.9 6.2 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EIE80257.1 - 0.0012 18.5 5.3 0.0012 18.5 3.7 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-Nse PF11789.3 EIE80257.1 - 0.0045 16.4 3.8 0.0089 15.5 2.7 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RanBP PF00641.13 EIE80257.1 - 0.0062 15.6 2.5 0.0062 15.6 1.7 1.7 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others ATP-synt_E PF05680.7 EIE80257.1 - 0.28 11.1 0.1 0.28 11.1 0.1 3.1 3 0 0 3 3 3 0 ATP synthase E chain zf-rbx1 PF12678.2 EIE80257.1 - 1.1 9.3 7.2 3.2 7.9 5.0 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger Thiolase_N PF00108.18 EIE80258.1 - 1e-82 277.1 3.9 1e-82 277.1 2.7 1.6 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EIE80258.1 - 4.8e-47 158.4 0.2 1e-46 157.3 0.1 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EIE80258.1 - 0.01 15.3 1.3 0.026 13.9 0.5 2.0 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.5 EIE80258.1 - 0.057 13.4 0.0 0.18 11.8 0.0 1.9 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal bZIP_1 PF00170.16 EIE80259.1 - 4.3e-08 32.9 16.2 4.3e-08 32.9 11.2 2.8 2 1 1 3 3 3 1 bZIP transcription factor bZIP_2 PF07716.10 EIE80259.1 - 5.6e-08 32.4 23.0 9.3e-08 31.7 9.7 3.4 3 1 1 4 4 4 2 Basic region leucine zipper bZIP_Maf PF03131.12 EIE80259.1 - 0.00071 19.8 13.8 0.00071 19.8 9.6 2.0 2 0 0 2 2 2 1 bZIP Maf transcription factor ATG16 PF08614.6 EIE80259.1 - 0.02 14.7 10.9 0.031 14.1 7.6 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) TSC22 PF01166.13 EIE80259.1 - 0.023 14.6 3.8 0.023 14.6 2.7 2.0 2 0 0 2 2 1 0 TSC-22/dip/bun family Jnk-SapK_ap_N PF09744.4 EIE80259.1 - 0.03 14.2 9.4 0.052 13.5 6.5 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 CASP_C PF08172.7 EIE80259.1 - 0.032 13.2 11.8 0.085 11.8 8.2 1.8 1 1 0 1 1 1 0 CASP C terminal DUF342 PF03961.8 EIE80259.1 - 0.058 11.8 7.5 0.067 11.5 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) APG6 PF04111.7 EIE80259.1 - 0.065 12.2 10.3 0.1 11.6 7.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 HALZ PF02183.13 EIE80259.1 - 0.073 12.7 1.0 0.073 12.7 0.7 3.0 2 1 1 3 3 3 0 Homeobox associated leucine zipper HSBP1 PF06825.7 EIE80259.1 - 0.087 12.4 0.4 0.17 11.5 0.3 1.5 1 0 0 1 1 1 0 Heat shock factor binding protein 1 Pox_A11 PF05061.8 EIE80259.1 - 0.16 10.9 6.2 0.2 10.7 4.3 1.1 1 0 0 1 1 1 0 Poxvirus A11 Protein Syntaxin-6_N PF09177.6 EIE80259.1 - 0.17 12.3 5.4 0.38 11.1 3.7 1.5 1 0 0 1 1 1 0 Syntaxin 6, N-terminal DUF4164 PF13747.1 EIE80259.1 - 0.2 11.8 11.0 0.37 10.9 7.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) FlaC_arch PF05377.6 EIE80259.1 - 0.28 11.1 4.0 3.5 7.5 2.6 2.4 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF607 PF04678.8 EIE80259.1 - 0.32 10.9 7.3 0.56 10.1 5.1 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF607 EMP24_GP25L PF01105.19 EIE80259.1 - 0.34 10.6 2.4 0.58 9.8 1.6 1.4 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD CCDC-167 PF15188.1 EIE80259.1 - 0.52 10.2 10.2 1.1 9.2 7.0 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 ARA70 PF12489.3 EIE80259.1 - 0.52 10.2 11.5 10 6.1 4.7 2.9 2 1 1 3 3 3 0 Nuclear coactivator DUF2968 PF11180.3 EIE80259.1 - 0.58 9.5 12.7 1.1 8.6 8.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) V_ATPase_I PF01496.14 EIE80259.1 - 0.64 7.7 5.3 0.8 7.4 3.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Prefoldin_2 PF01920.15 EIE80259.1 - 0.69 9.6 13.7 2.1 8.1 9.5 1.8 1 1 0 1 1 1 0 Prefoldin subunit End3 PF12761.2 EIE80259.1 - 0.7 9.5 11.7 1.3 8.6 8.1 1.4 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 NTR2 PF15458.1 EIE80259.1 - 1.9 7.6 15.5 20 4.3 0.0 2.6 1 1 1 3 3 3 0 Nineteen complex-related protein 2 DUF4094 PF13334.1 EIE80259.1 - 2.2 8.7 7.4 2.8 8.3 3.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) Spc24 PF08286.6 EIE80259.1 - 4.4 7.0 9.4 0.77 9.4 3.4 1.9 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 PspB PF06667.7 EIE80259.1 - 5 7.1 8.0 0.74 9.7 1.7 2.2 1 1 1 2 2 2 0 Phage shock protein B Bap31 PF05529.7 EIE80259.1 - 5 6.5 7.7 9.8 5.5 5.4 1.4 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like IncA PF04156.9 EIE80259.1 - 6.8 6.2 17.7 14 5.1 12.3 1.5 1 1 0 1 1 1 0 IncA protein Methyltransf_31 PF13847.1 EIE80260.1 - 9e-15 54.5 0.0 1.2e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIE80260.1 - 5.3e-12 46.2 0.0 8.6e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EIE80260.1 - 1.1e-07 31.4 0.0 1.6e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EIE80260.1 - 5.2e-07 29.7 0.0 6.8e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIE80260.1 - 1.1e-06 29.0 0.1 4.5e-06 27.0 0.0 2.0 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIE80260.1 - 3.5e-06 27.3 0.0 5.8e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIE80260.1 - 3.8e-06 26.7 0.0 6.4e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIE80260.1 - 6.1e-06 26.6 0.0 1.1e-05 25.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.8 EIE80260.1 - 1.9e-05 24.7 0.0 2.9e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_32 PF13679.1 EIE80260.1 - 7.3e-05 22.4 0.0 0.0001 21.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 EIE80260.1 - 0.00011 21.6 0.0 0.00016 21.1 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW tRNA_U5-meth_tr PF05958.6 EIE80260.1 - 0.00016 20.5 0.0 0.00024 19.9 0.0 1.2 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_4 PF02390.12 EIE80260.1 - 0.00019 20.5 0.0 0.00051 19.1 0.0 1.7 1 1 0 1 1 1 1 Putative methyltransferase TehB PF03848.9 EIE80260.1 - 0.00024 20.3 0.0 0.00038 19.6 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_9 PF08003.6 EIE80260.1 - 0.0014 17.3 0.0 0.0026 16.4 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) PrmA PF06325.8 EIE80260.1 - 0.0019 17.3 0.0 0.0026 16.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) DOT1 PF08123.8 EIE80260.1 - 0.0048 16.2 0.0 0.0069 15.7 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 TPMT PF05724.6 EIE80260.1 - 0.042 13.2 0.0 0.078 12.4 0.0 1.4 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) RrnaAD PF00398.15 EIE80260.1 - 0.057 12.4 0.0 0.08 11.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Transposase_24 PF03004.9 EIE80262.1 - 0.086 12.7 0.3 0.086 12.7 0.2 2.3 2 1 0 2 2 2 0 Plant transposase (Ptta/En/Spm family) SieB PF14163.1 EIE80262.1 - 0.73 9.3 2.7 3.2 7.2 0.1 2.3 2 0 0 2 2 2 0 Superinfection exclusion protein B Amino_oxidase PF01593.19 EIE80266.1 - 4.6e-17 62.2 0.0 2.4e-10 40.1 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EIE80266.1 - 9.9e-10 38.3 0.0 2.1e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EIE80266.1 - 3.7e-08 32.6 0.0 7.7e-07 28.3 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EIE80266.1 - 0.00019 21.4 0.0 0.01 15.7 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EIE80266.1 - 0.00032 19.8 0.1 0.00065 18.8 0.1 1.5 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 EIE80266.1 - 0.0022 17.7 0.0 0.053 13.3 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 EIE80266.1 - 0.0032 17.8 0.0 0.012 15.9 0.0 2.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EIE80266.1 - 0.0068 15.0 0.1 0.01 14.5 0.0 1.2 1 0 0 1 1 1 1 Tryptophan halogenase GIDA PF01134.17 EIE80266.1 - 0.0081 15.0 0.1 0.22 10.3 0.0 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 EIE80266.1 - 0.087 11.8 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Strep_67kDa_ant PF06100.6 EIE80266.1 - 0.14 10.4 0.0 0.2 10.0 0.0 1.2 1 0 0 1 1 1 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family DnaJ PF00226.26 EIE80267.1 - 4.5e-21 74.3 0.4 7.2e-21 73.7 0.3 1.3 1 0 0 1 1 1 1 DnaJ domain DUF1183 PF06682.7 EIE80267.1 - 0.089 12.3 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) Gly-zipper_YMGG PF13441.1 EIE80267.1 - 0.16 11.4 5.6 0.22 11.0 3.9 1.2 1 0 0 1 1 1 0 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.1 EIE80267.1 - 1.2 8.7 6.3 2 8.1 4.3 1.2 1 0 0 1 1 1 0 Glycine zipper GATA PF00320.22 EIE80268.1 - 1.6e-30 104.0 18.2 1.4e-15 56.2 3.6 2.6 2 0 0 2 2 2 2 GATA zinc finger ArfGap PF01412.13 EIE80268.1 - 0.0011 18.7 2.5 0.13 12.0 0.1 2.4 2 0 0 2 2 2 2 Putative GTPase activating protein for Arf TF_Zn_Ribbon PF08271.7 EIE80268.1 - 0.0031 16.8 3.9 0.24 10.7 0.2 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding Cytochrome_C7 PF14522.1 EIE80268.1 - 0.043 13.4 0.7 0.043 13.4 0.5 2.5 2 0 0 2 2 2 0 Cytochrome c7 Cytochrom_c3_2 PF14537.1 EIE80268.1 - 0.074 13.3 9.7 0.16 12.3 1.1 2.4 2 0 0 2 2 2 0 Cytochrome c3 Cytochrom_C PF00034.16 EIE80268.1 - 0.083 13.7 1.1 0.2 12.5 0.7 1.6 1 0 0 1 1 1 0 Cytochrome c NMD3 PF04981.8 EIE80268.1 - 0.26 10.3 3.1 1.8 7.6 0.1 2.2 2 0 0 2 2 2 0 NMD3 family DZR PF12773.2 EIE80268.1 - 0.57 10.0 10.3 6.2 6.7 0.4 2.6 2 1 1 3 3 3 0 Double zinc ribbon zf-DBF PF07535.7 EIE80268.1 - 1.3 8.7 4.8 23 4.7 1.1 2.8 2 0 0 2 2 2 0 DBF zinc finger OrfB_Zn_ribbon PF07282.6 EIE80268.1 - 1.6 8.4 8.8 2.1 8.0 0.5 3.2 2 1 1 3 3 3 0 Putative transposase DNA-binding domain eIF-5_eIF-2B PF01873.12 EIE80268.1 - 2.4 7.8 6.7 5.7 6.6 0.7 2.4 2 0 0 2 2 2 0 Domain found in IF2B/IF5 zf-3CxxC PF13695.1 EIE80268.1 - 6.4 7.0 9.4 0.52 10.5 0.6 2.5 2 1 1 3 3 3 0 Zinc-binding domain zf-C2H2 PF00096.21 EIE80271.1 - 5.8 7.4 9.1 0.19 12.1 1.1 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type ACC_central PF08326.7 EIE80272.1 - 1.6e-228 760.4 1.1 2e-228 760.0 0.7 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 EIE80272.1 - 1.9e-167 557.5 0.0 2.9e-167 556.9 0.0 1.3 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 EIE80272.1 - 3.8e-54 183.1 0.0 9.3e-54 181.9 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 EIE80272.1 - 5.2e-26 90.9 0.1 1.2e-25 89.7 0.1 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EIE80272.1 - 7.9e-22 77.2 0.0 1.9e-20 72.8 0.0 3.1 3 0 0 3 3 3 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 EIE80272.1 - 3e-15 55.6 0.0 6.7e-15 54.4 0.0 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 EIE80272.1 - 6.8e-13 48.7 0.0 2e-12 47.2 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 EIE80272.1 - 0.00021 21.1 0.0 0.00094 19.0 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EIE80272.1 - 0.001 18.4 0.0 0.003 16.9 0.0 1.8 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EIE80272.1 - 0.003 16.9 0.0 0.0081 15.5 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 EIE80272.1 - 0.012 15.1 0.0 0.066 12.6 0.0 2.1 1 1 0 1 1 1 0 RimK-like ATP-grasp domain Biotin_lipoyl_2 PF13533.1 EIE80272.1 - 0.031 13.9 0.0 0.1 12.2 0.0 1.9 1 0 0 1 1 1 0 Biotin-lipoyl like DDE_3 PF13358.1 EIE80273.1 - 1.7e-09 37.5 0.0 1.8e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1617 PF07761.7 EIE80273.1 - 0.096 12.7 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1617) Vps5 PF09325.5 EIE80273.1 - 0.13 11.4 0.4 0.15 11.2 0.2 1.1 1 0 0 1 1 1 0 Vps5 C terminal like TMF_TATA_bd PF12325.3 EIE80274.1 - 0.0028 17.3 0.7 0.0036 17.0 0.5 1.2 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding DUF3450 PF11932.3 EIE80274.1 - 0.024 13.9 4.1 0.024 13.8 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) CENP-F_leu_zip PF10473.4 EIE80274.1 - 0.034 13.9 0.9 0.049 13.4 0.6 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF972 PF06156.8 EIE80274.1 - 0.036 14.4 0.6 0.044 14.1 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) KaiC PF06745.8 EIE80274.1 - 0.058 12.5 0.1 0.07 12.2 0.1 1.1 1 0 0 1 1 1 0 KaiC TBPIP PF07106.8 EIE80274.1 - 0.098 12.1 2.0 0.13 11.7 1.4 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Neurexophilin PF06312.7 EIE80274.1 - 0.14 11.4 1.8 0.15 11.2 0.3 1.7 1 1 0 2 2 2 0 Neurexophilin Sec20 PF03908.8 EIE80274.1 - 0.24 11.1 2.4 0.36 10.5 1.0 1.8 1 1 1 2 2 2 0 Sec20 QPP PF07640.6 EIE80274.1 - 0.26 10.9 0.4 0.26 10.9 0.2 2.3 2 0 0 2 2 2 0 QPP PUF PF00806.14 EIE80275.1 - 1.7e-68 222.3 16.1 4.7e-09 35.2 0.0 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat EphA2_TM PF14575.1 EIE80279.1 - 5.5 7.4 0.0 5.5 7.4 0.0 4.4 2 1 1 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Glyco_transf_15 PF01793.11 EIE80280.1 - 2.8e-113 378.2 10.2 5.3e-111 370.7 7.1 2.0 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Glyco_transf_15 PF01793.11 EIE80281.1 - 3.1e-115 384.6 10.8 3.7e-115 384.3 7.5 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Lipoprotein_8 PF02030.10 EIE80282.1 - 0.063 11.7 0.7 0.07 11.6 0.5 1.0 1 0 0 1 1 1 0 Hypothetical lipoprotein (MG045 family) Pribosyl_synth PF14572.1 EIE80283.1 - 3.3e-47 160.6 3.7 9.4e-38 129.7 1.7 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 EIE80283.1 - 3.6e-46 155.6 1.4 2.7e-45 152.8 0.1 2.3 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 EIE80283.1 - 5.5e-12 45.5 0.9 9.5e-11 41.5 0.4 2.3 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EIE80283.1 - 0.044 12.9 0.3 0.091 11.9 0.2 1.5 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase MFS_1 PF07690.11 EIE80286.1 - 1.5e-30 106.1 22.9 1.1e-25 90.1 11.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.3 EIE80286.1 - 0.0014 17.2 0.2 0.0014 17.2 0.1 2.2 2 1 1 3 3 3 1 Vacuole effluxer Atg22 like YL1 PF05764.8 EIE80287.1 - 4.6e-05 23.1 17.9 4.9e-05 23.0 12.4 1.0 1 0 0 1 1 1 1 YL1 nuclear protein LRR_4 PF12799.2 EIE80288.1 - 0.015 14.8 0.5 0.063 12.9 0.0 2.2 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) GCOM2 PF15328.1 EIE80288.1 - 0.028 14.1 3.9 0.037 13.7 2.7 1.3 1 0 0 1 1 1 0 Putative GRINL1B complex locus protein 2 DUF465 PF04325.8 EIE80288.1 - 0.075 12.7 2.2 1.3 8.8 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF465) ATP11 PF06644.6 EIE80289.1 - 2.3e-67 227.3 4.3 2.7e-67 227.0 3.0 1.1 1 0 0 1 1 1 1 ATP11 protein Histone_HNS PF00816.16 EIE80289.1 - 0.056 13.9 4.2 0.12 12.9 2.9 1.5 1 0 0 1 1 1 0 H-NS histone family PTPlike_phytase PF14566.1 EIE80289.1 - 0.15 12.0 1.9 0.34 10.9 1.4 1.6 1 1 0 1 1 1 0 Inositol hexakisphosphate Lsr2 PF11774.3 EIE80289.1 - 0.28 11.0 1.7 0.6 10.0 0.5 1.9 2 0 0 2 2 2 0 Lsr2 MttA_Hcf106 PF02416.11 EIE80289.1 - 0.69 9.0 3.1 1.4 8.1 2.1 1.4 1 0 0 1 1 1 0 mttA/Hcf106 family 60KD_IMP PF02096.15 EIE80290.1 - 4.7e-45 153.7 2.9 4.7e-45 153.7 2.0 1.7 2 0 0 2 2 2 1 60Kd inner membrane protein DPBB_1 PF03330.13 EIE80292.1 - 2.1e-08 34.0 0.2 5.1e-08 32.8 0.1 1.7 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EIE80292.1 - 0.0036 16.9 0.3 0.0065 16.1 0.1 1.4 1 1 0 1 1 1 1 Barwin family CUE PF02845.11 EIE80293.1 - 1.3e-11 43.7 0.0 2e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 CUE domain PP2C PF00481.16 EIE80294.1 - 8.1e-15 54.9 0.1 1e-13 51.2 0.0 2.8 1 1 1 2 2 2 1 Protein phosphatase 2C PP2C_2 PF13672.1 EIE80294.1 - 1e-07 31.5 0.0 1e-06 28.3 0.0 2.2 2 0 0 2 2 2 1 Protein phosphatase 2C DUF2834 PF11196.3 EIE80294.1 - 3.7e-06 27.0 7.1 0.022 14.9 0.5 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF2834) Glycos_transf_2 PF00535.21 EIE80295.1 - 2.2e-33 115.3 0.0 2.7e-33 115.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EIE80295.1 - 4.2e-11 43.0 0.0 7.8e-11 42.2 0.0 1.3 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 EIE80295.1 - 4.2e-11 42.4 0.0 5.7e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EIE80295.1 - 0.0021 17.3 0.0 0.0032 16.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Rab3-GTPase_cat PF13890.1 EIE80296.1 - 1e-53 181.1 0.2 1e-53 181.1 0.1 1.8 2 0 0 2 2 2 1 Rab3 GTPase-activating protein catalytic subunit zf-RVT PF13966.1 EIE80297.1 - 6.9e-06 26.2 1.5 6.9e-06 26.2 1.0 2.1 3 0 0 3 3 3 1 zinc-binding in reverse transcriptase Nucleotid_trans PF03407.11 EIE80298.1 - 0.083 12.6 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase UAA PF08449.6 EIE80300.1 - 9.4e-82 274.3 21.1 1.1e-81 274.1 14.6 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 EIE80300.1 - 2.8e-17 62.9 13.5 3.1e-11 43.3 3.2 2.5 2 1 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 EIE80300.1 - 9.5e-07 29.0 14.9 0.00022 21.3 3.8 3.0 3 1 0 3 3 3 2 Multidrug resistance efflux transporter TPT PF03151.11 EIE80300.1 - 1.9e-05 24.3 20.0 0.00079 19.0 5.6 2.9 2 1 0 2 2 2 2 Triose-phosphate Transporter family Nuc_sug_transp PF04142.10 EIE80300.1 - 8.1e-05 21.8 10.9 0.00057 19.0 1.2 2.7 1 1 2 3 3 3 2 Nucleotide-sugar transporter DUF914 PF06027.7 EIE80300.1 - 0.003 16.4 13.3 0.0044 15.9 9.1 1.3 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) DUF1003 PF06210.6 EIE80300.1 - 0.091 12.6 2.0 0.23 11.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1003) Internalin_N PF12354.3 EIE80300.1 - 0.3 10.7 3.7 5.5 6.6 0.0 4.0 4 1 0 4 4 4 0 Bacterial adhesion/invasion protein N terminal AAA PF00004.24 EIE80301.1 - 3.1e-31 108.3 0.2 1.8e-29 102.5 0.1 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EIE80301.1 - 1.5e-05 24.9 0.0 2.4e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 EIE80301.1 - 2.3e-05 24.3 0.0 3.1e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EIE80301.1 - 7.9e-05 21.8 0.0 0.00015 20.9 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EIE80301.1 - 9.9e-05 23.1 0.0 0.00014 22.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EIE80301.1 - 0.0001 22.1 0.0 0.00015 21.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EIE80301.1 - 0.00014 21.9 0.2 0.0016 18.5 0.1 2.4 1 1 1 2 2 2 1 AAA domain TIP49 PF06068.8 EIE80301.1 - 0.00042 19.1 0.6 0.0061 15.3 0.1 2.4 2 1 1 3 3 3 2 TIP49 C-terminus AAA_16 PF13191.1 EIE80301.1 - 0.00053 20.0 0.1 0.0031 17.5 0.1 2.0 1 1 1 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 EIE80301.1 - 0.00065 19.1 0.1 0.0084 15.5 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.1 EIE80301.1 - 0.0011 19.3 0.0 0.0018 18.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 EIE80301.1 - 0.0012 18.6 0.0 0.0016 18.3 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_5 PF07728.9 EIE80301.1 - 0.0014 18.3 0.0 0.0049 16.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 EIE80301.1 - 0.0022 17.4 0.0 0.0034 16.8 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein ABC_tran PF00005.22 EIE80301.1 - 0.0052 17.0 0.0 0.0073 16.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter IPT PF01745.11 EIE80301.1 - 0.01 14.9 0.0 0.02 14.0 0.0 1.4 1 0 0 1 1 1 0 Isopentenyl transferase RNA_helicase PF00910.17 EIE80301.1 - 0.015 15.4 0.0 0.034 14.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Zeta_toxin PF06414.7 EIE80301.1 - 0.015 14.4 0.0 0.025 13.6 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Mg_chelatase PF01078.16 EIE80301.1 - 0.018 14.1 0.0 0.029 13.5 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Guanylate_kin PF00625.16 EIE80301.1 - 0.021 14.2 0.1 2.6 7.4 0.0 2.3 1 1 1 2 2 2 0 Guanylate kinase T2SE PF00437.15 EIE80301.1 - 0.023 13.5 0.0 0.034 13.0 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.7 EIE80301.1 - 0.024 14.2 0.3 0.11 12.1 0.1 1.9 2 0 0 2 2 2 0 NACHT domain AFG1_ATPase PF03969.11 EIE80301.1 - 0.031 13.0 0.0 0.05 12.4 0.0 1.2 1 0 0 1 1 1 0 AFG1-like ATPase AAA_28 PF13521.1 EIE80301.1 - 0.033 14.1 0.0 0.051 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Bac_DnaA PF00308.13 EIE80301.1 - 0.036 13.7 0.0 0.056 13.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial dnaA protein DUF815 PF05673.8 EIE80301.1 - 0.06 12.2 0.0 0.47 9.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.21 EIE80301.1 - 0.11 11.9 0.1 0.23 10.8 0.0 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain UPF0079 PF02367.12 EIE80301.1 - 0.11 12.0 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 DUF258 PF03193.11 EIE80301.1 - 0.13 11.4 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 WD40 PF00400.27 EIE80302.1 - 3.6e-24 83.7 19.6 4.8e-08 32.5 0.2 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 EIE80302.1 - 1.2e-05 25.1 0.7 0.015 15.0 0.1 3.2 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 EIE80302.1 - 0.0044 16.1 0.1 0.21 10.6 0.0 2.6 2 1 0 2 2 2 1 Neuroblastoma-amplified sequence, N terminal DUF1513 PF07433.6 EIE80302.1 - 0.006 15.5 0.8 0.034 13.0 0.1 2.3 1 1 2 3 3 3 1 Protein of unknown function (DUF1513) DUF1399 PF07173.7 EIE80303.1 - 0.086 13.1 0.1 0.15 12.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1399) DUF262 PF03235.9 EIE80303.1 - 0.24 11.3 3.1 0.41 10.5 1.0 1.7 1 1 1 2 2 2 0 Protein of unknown function DUF262 Glycos_transf_1 PF00534.15 EIE80305.1 - 2.1e-24 85.8 0.0 2.6e-24 85.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EIE80305.1 - 4.8e-11 42.9 0.0 7.4e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EIE80305.1 - 6.1e-05 23.2 0.0 0.00014 22.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 polyprenyl_synt PF00348.12 EIE80306.1 - 1.1e-55 188.2 0.0 1.3e-55 188.0 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase VPS11_C PF12451.3 EIE80307.1 - 0.034 13.9 0.2 0.034 13.9 0.1 1.7 2 0 0 2 2 2 0 Vacuolar protein sorting protein 11 C terminal Rav1p_C PF12234.3 EIE80308.1 - 5e-153 510.5 3.2 7e-153 510.1 2.2 1.2 1 0 0 1 1 1 1 RAVE protein 1 C terminal TLD PF07534.11 EIE80310.1 - 8.9e-42 142.3 3.1 1.8e-39 134.9 0.4 2.1 2 0 0 2 2 2 2 TLD Amidinotransf PF02274.12 EIE80311.1 - 7.9e-22 77.6 0.2 3.1e-14 52.7 0.0 2.0 1 1 1 2 2 2 2 Amidinotransferase Lustrin_cystein PF14625.1 EIE80312.1 - 0.14 12.2 12.7 0.18 11.8 8.8 1.3 1 0 0 1 1 1 0 Lustrin, cysteine-rich repeated domain HEV_ORF1 PF02444.11 EIE80312.1 - 7.4 6.8 14.2 2.2 8.4 1.9 2.0 1 1 1 2 2 2 0 Hepatitis E virus ORF-2 (Putative capsid protein) CotH PF08757.6 EIE80313.1 - 2.2e-29 102.7 4.8 3.3e-29 102.1 3.3 1.2 1 0 0 1 1 1 1 CotH protein DUF1325 PF07039.6 EIE80314.1 - 1.4e-29 102.3 0.2 2e-29 101.8 0.1 1.2 1 0 0 1 1 1 1 SGF29 tudor-like domain Agenet PF05641.7 EIE80314.1 - 0.012 15.7 0.2 2.6 8.2 0.0 2.4 2 0 0 2 2 2 0 Agenet domain DUF4537 PF15057.1 EIE80314.1 - 0.022 14.5 0.2 0.4 10.4 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4537) TUDOR PF00567.19 EIE80314.1 - 0.051 13.4 0.2 30 4.4 0.0 3.0 2 1 1 3 3 3 0 Tudor domain CDO_I PF05995.7 EIE80315.1 - 3.8e-47 159.7 0.3 5.9e-47 159.0 0.2 1.3 1 0 0 1 1 1 1 Cysteine dioxygenase type I DUF1637 PF07847.7 EIE80315.1 - 3.8e-09 36.1 0.0 5.1e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1637) Choline_sulf_C PF12411.3 EIE80315.1 - 0.075 12.8 0.2 0.15 11.8 0.1 1.4 1 0 0 1 1 1 0 Choline sulfatase enzyme C terminal ETF_QO PF05187.8 EIE80316.1 - 5.4e-45 151.8 0.0 8.7e-45 151.2 0.0 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase FAD_binding_2 PF00890.19 EIE80316.1 - 1.1e-08 34.3 0.5 1.6e-05 23.9 1.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EIE80316.1 - 2.4e-08 33.2 0.3 0.00036 19.5 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIE80316.1 - 6.6e-06 26.0 0.1 2.5e-05 24.2 0.0 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EIE80316.1 - 2.4e-05 24.3 0.0 4e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EIE80316.1 - 3e-05 23.3 0.0 4.8e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 EIE80316.1 - 4.7e-05 22.5 0.0 0.00052 19.1 0.1 2.0 2 0 0 2 2 2 1 Thi4 family Fer4_7 PF12838.2 EIE80316.1 - 0.00013 22.2 1.2 0.0004 20.7 0.8 1.8 1 0 0 1 1 1 1 4Fe-4S dicluster domain HI0933_like PF03486.9 EIE80316.1 - 0.00013 20.5 0.5 0.00028 19.4 0.4 1.5 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 EIE80316.1 - 0.00016 22.0 0.2 0.049 14.0 0.2 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EIE80316.1 - 0.00016 21.4 0.2 0.00049 19.9 0.1 1.9 1 1 0 1 1 1 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 EIE80316.1 - 0.00021 20.5 0.2 0.0004 19.5 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.9 EIE80316.1 - 0.00049 18.8 0.2 0.0094 14.6 0.3 2.1 2 0 0 2 2 2 1 Tryptophan halogenase Lycopene_cycl PF05834.7 EIE80316.1 - 0.003 16.5 0.1 0.0043 16.0 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EIE80316.1 - 0.01 15.8 0.1 0.032 14.3 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Fer4_10 PF13237.1 EIE80316.1 - 0.029 14.1 1.1 0.061 13.1 0.7 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain GIDA PF01134.17 EIE80316.1 - 0.13 11.0 0.8 0.18 10.6 0.6 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A MIT PF04212.13 EIE80317.1 - 3.6e-05 23.5 0.0 0.0015 18.3 0.0 2.4 2 0 0 2 2 2 2 MIT (microtubule interacting and transport) domain Ribosomal_L36e PF01158.13 EIE80318.1 - 1.1e-38 131.1 5.0 1.2e-38 131.0 3.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e LemA PF04011.7 EIE80318.1 - 0.0019 17.3 0.1 0.0019 17.3 0.1 1.1 1 0 0 1 1 1 1 LemA family 4HB_MCP_1 PF12729.2 EIE80318.1 - 0.014 14.7 0.1 0.017 14.4 0.0 1.1 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction priB_priC PF07445.7 EIE80318.1 - 0.052 13.0 0.1 0.058 12.8 0.0 1.1 1 0 0 1 1 1 0 Primosomal replication protein priB and priC zf-C2H2_4 PF13894.1 EIE80319.1 - 9.4e-07 28.7 16.0 0.0018 18.4 3.0 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EIE80319.1 - 2.8e-05 24.1 12.2 8.2e-05 22.7 1.0 2.8 2 1 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.21 EIE80319.1 - 0.00031 20.9 16.7 0.025 14.9 4.1 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_5 PF13909.1 EIE80319.1 - 0.0049 17.0 4.0 0.0049 17.0 2.7 3.4 3 0 0 3 3 3 1 C2H2-type zinc-finger domain zf-Di19 PF05605.7 EIE80319.1 - 0.038 14.1 9.3 0.062 13.4 5.5 1.9 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DUF2321 PF10083.4 EIE80319.1 - 0.13 11.7 1.9 0.15 11.5 0.6 1.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) zf-FCS PF06467.9 EIE80319.1 - 0.16 11.6 4.0 0.59 9.8 2.7 2.1 1 1 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif Zn_Tnp_IS1595 PF12760.2 EIE80319.1 - 0.94 9.3 5.9 2 8.2 4.1 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-C2H2_jaz PF12171.3 EIE80319.1 - 1.9 8.7 11.9 2.6 8.3 3.2 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Methyltransf_23 PF13489.1 EIE80320.1 - 9.2e-11 41.7 0.0 1.4e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIE80320.1 - 6.3e-10 39.4 0.0 1.1e-09 38.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIE80320.1 - 6.7e-10 38.7 0.0 1.1e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIE80320.1 - 1.1e-07 32.3 0.0 1.9e-07 31.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIE80320.1 - 2.4e-05 23.5 0.0 3.6e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EIE80320.1 - 0.00011 22.5 0.0 0.0002 21.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIE80320.1 - 0.00074 19.8 0.0 0.0023 18.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 EIE80320.1 - 0.0036 16.3 0.0 0.0071 15.4 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase TPMT PF05724.6 EIE80320.1 - 0.0096 15.3 0.1 0.15 11.4 0.0 2.6 1 1 2 3 3 3 1 Thiopurine S-methyltransferase (TPMT) CheR PF01739.13 EIE80320.1 - 0.043 13.1 0.0 0.094 11.9 0.0 1.6 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain MTS PF05175.9 EIE80320.1 - 0.065 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain FAD_binding_6 PF00970.19 EIE80321.1 - 5.4e-32 109.8 0.0 8.8e-32 109.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EIE80321.1 - 2.6e-29 101.9 0.0 1.1e-28 99.9 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EIE80321.1 - 2.1e-08 34.2 0.0 5e-05 23.2 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EIE80321.1 - 0.00077 19.4 0.0 0.0013 18.6 0.0 1.4 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain CH PF00307.26 EIE80322.1 - 2.4e-22 79.0 3.8 4.4e-12 45.9 0.3 3.6 2 1 1 3 3 3 2 Calponin homology (CH) domain EF-hand_6 PF13405.1 EIE80322.1 - 6.2e-05 22.5 0.7 0.0013 18.4 0.0 3.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.27 EIE80322.1 - 0.00012 21.1 0.3 0.001 18.1 0.0 2.7 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 EIE80322.1 - 0.00038 20.5 0.7 0.0014 18.7 0.5 2.0 1 0 0 1 1 1 1 EF-hand domain pair Spectrin PF00435.16 EIE80322.1 - 0.0035 17.5 0.4 0.0035 17.5 0.3 2.6 3 0 0 3 3 3 1 Spectrin repeat DASH_Duo1 PF08651.5 EIE80322.1 - 0.014 14.9 1.3 0.1 12.1 0.6 2.6 1 1 1 2 2 2 0 DASH complex subunit Duo1 EF-hand_5 PF13202.1 EIE80322.1 - 0.018 14.3 0.0 0.068 12.5 0.0 2.0 1 0 0 1 1 1 0 EF hand CAMSAP_CH PF11971.3 EIE80322.1 - 0.034 13.7 0.7 0.78 9.4 0.0 3.1 3 0 0 3 3 3 0 CAMSAP CH domain Seryl_tRNA_N PF02403.17 EIE80322.1 - 0.052 13.5 1.5 0.17 11.9 0.5 2.4 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Translat_reg PF01818.12 EIE80322.1 - 0.074 12.5 2.1 1.8 8.0 0.3 3.3 3 1 0 3 3 3 0 Bacteriophage translational regulator Homeobox PF00046.24 EIE80324.1 - 1.4e-19 69.4 2.1 1.4e-19 69.4 1.4 2.6 2 0 0 2 2 2 1 Homeobox domain Homeobox_KN PF05920.6 EIE80324.1 - 0.041 13.5 0.7 0.15 11.8 0.1 2.2 2 0 0 2 2 2 0 Homeobox KN domain HTH_23 PF13384.1 EIE80324.1 - 0.088 12.4 0.2 0.2 11.3 0.2 1.6 1 0 0 1 1 1 0 Homeodomain-like domain MS_channel PF00924.13 EIE80325.1 - 7.4e-17 61.3 1.1 1e-16 60.8 0.8 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 EIE80325.1 - 1.8e-06 26.8 0.2 4.4e-06 25.5 0.2 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 EIE80325.1 - 4.5e-05 22.9 0.1 0.00013 21.5 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.1 EIE80325.1 - 0.00012 21.2 0.4 0.00039 19.6 0.3 1.9 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 EIE80325.1 - 0.0006 19.8 0.1 0.0014 18.6 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 EIE80325.1 - 0.0082 15.7 0.1 0.019 14.5 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair CHCH PF06747.8 EIE80326.1 - 0.00023 20.9 1.4 0.00029 20.6 1.0 1.1 1 0 0 1 1 1 1 CHCH domain adh_short PF00106.20 EIE80327.1 - 5.9e-26 91.3 0.1 8.4e-26 90.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIE80327.1 - 4.8e-13 49.1 0.0 7.7e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EIE80327.1 - 1.7e-07 31.2 0.0 2.4e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 EIE80327.1 - 0.00028 20.6 0.4 0.00074 19.2 0.3 1.8 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EIE80327.1 - 0.00034 20.1 0.0 0.00051 19.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EIE80327.1 - 0.06 12.0 0.3 0.1 11.2 0.2 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EIE80327.1 - 0.097 11.5 0.2 0.15 10.9 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein PGP_phosphatase PF09419.5 EIE80328.1 - 7.3e-28 97.0 0.0 1e-13 50.9 0.0 2.0 1 1 1 2 2 2 2 Mitochondrial PGP phosphatase Hydrolase_like PF13242.1 EIE80328.1 - 0.00024 20.7 0.0 0.00034 20.2 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EIE80328.1 - 0.0092 16.4 0.0 0.54 10.6 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase AAA_5 PF07728.9 EIE80330.1 - 6.1e-71 236.5 0.1 3.2e-25 88.4 0.0 3.9 3 1 1 4 4 4 3 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EIE80330.1 - 2.9e-07 30.6 1.0 0.089 12.7 0.1 4.7 4 2 1 5 5 5 2 AAA ATPase domain AAA_22 PF13401.1 EIE80330.1 - 1.8e-05 24.9 0.2 0.14 12.2 0.0 3.6 2 1 0 2 2 2 2 AAA domain VWA_2 PF13519.1 EIE80330.1 - 8.2e-05 22.7 0.0 0.00021 21.4 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain AAA_3 PF07726.6 EIE80330.1 - 0.0042 16.6 0.0 1.3 8.5 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 EIE80330.1 - 0.014 15.5 0.0 8.5 6.5 0.0 3.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EIE80330.1 - 0.044 14.6 0.0 0.97 10.2 0.0 3.3 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 EIE80330.1 - 0.053 12.6 0.1 7.2 5.7 0.0 3.3 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI RuvB_N PF05496.7 EIE80330.1 - 0.055 12.5 0.6 2.2 7.2 0.0 3.3 3 1 0 3 3 3 0 Holliday junction DNA helicase ruvB N-terminus DUF2201_N PF13203.1 EIE80330.1 - 0.87 8.7 5.0 1.6 7.8 3.5 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain UBX PF00789.15 EIE80331.1 - 6.9e-14 51.6 0.0 1.3e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 UBX domain MAP7 PF05672.6 EIE80331.1 - 0.0025 17.2 16.3 0.0033 16.8 11.3 1.2 1 0 0 1 1 1 1 MAP7 (E-MAP-115) family BTV_NS2 PF04514.7 EIE80331.1 - 0.4 9.5 8.7 0.57 9.0 6.0 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 AAA_23 PF13476.1 EIE80331.1 - 2.2 8.5 8.8 3.6 7.8 6.1 1.3 1 0 0 1 1 1 0 AAA domain DDRGK PF09756.4 EIE80331.1 - 3.9 6.8 19.0 6.1 6.2 13.2 1.2 1 0 0 1 1 1 0 DDRGK domain Macoilin PF09726.4 EIE80331.1 - 7.7 4.6 11.5 9.7 4.3 8.0 1.1 1 0 0 1 1 1 0 Transmembrane protein KilA-N PF04383.8 EIE80332.1 - 0.0021 17.6 0.1 0.0021 17.6 0.1 2.8 2 1 0 2 2 2 1 KilA-N domain Patatin PF01734.17 EIE80332.1 - 0.0046 16.9 0.0 0.0053 16.7 0.0 1.3 1 1 0 1 1 1 1 Patatin-like phospholipase Mucin PF01456.12 EIE80332.1 - 4.1 7.1 12.2 17 5.1 6.0 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein Ribosomal_S15 PF00312.17 EIE80333.1 - 3.1e-24 84.5 2.1 6.4e-24 83.5 1.4 1.5 1 0 0 1 1 1 1 Ribosomal protein S15 DHHA2 PF02833.9 EIE80335.1 - 1.3e-19 70.6 0.0 2.5e-19 69.7 0.0 1.5 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.15 EIE80335.1 - 4.5e-09 36.1 0.0 8.3e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 DHH family YdjO PF14169.1 EIE80338.1 - 0.033 13.6 0.8 0.039 13.4 0.0 1.7 2 0 0 2 2 2 0 Cold-inducible protein YdjO RE_MjaI PF09568.5 EIE80338.1 - 0.037 13.5 0.1 0.9 9.0 0.0 2.0 1 1 1 2 2 2 0 MjaI restriction endonuclease Retrotrans_gag PF03732.12 EIE80338.1 - 0.099 12.7 0.0 0.15 12.1 0.0 1.2 1 1 0 1 1 1 0 Retrotransposon gag protein DUF4452 PF14618.1 EIE80341.1 - 0.82 9.4 6.3 8.3 6.2 1.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4452) RVT_1 PF00078.22 EIE80342.1 - 2.2e-05 23.9 0.0 6.3e-05 22.4 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) EB PF01683.13 EIE80343.1 - 0.0061 16.5 15.7 0.04 13.9 5.1 3.3 3 1 1 4 4 4 2 EB module Dickkopf_N PF04706.7 EIE80343.1 - 0.76 9.9 16.9 0.32 11.1 3.8 2.7 3 0 0 3 3 3 0 Dickkopf N-terminal cysteine-rich region tRNA-synt_2b PF00587.20 EIE80344.1 - 3.8e-46 156.8 0.0 6.9e-46 155.9 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EIE80344.1 - 4e-17 61.9 0.0 7.9e-17 60.9 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_His PF13393.1 EIE80344.1 - 0.017 14.1 0.0 0.025 13.6 0.0 1.2 1 0 0 1 1 1 0 Histidyl-tRNA synthetase RTP801_C PF07809.6 EIE80344.1 - 0.056 13.1 0.0 0.091 12.4 0.0 1.3 1 0 0 1 1 1 0 RTP801 C-terminal region DUF2470 PF10615.4 EIE80345.1 - 7.3e-09 35.7 0.0 8.3e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) DUF4448 PF14610.1 EIE80346.1 - 3.9e-05 23.2 0.1 4.7e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) GPI-anchored PF10342.4 EIE80346.1 - 0.00018 21.8 2.5 0.00034 21.0 1.7 1.4 1 1 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family RCR PF12273.3 EIE80346.1 - 0.11 13.1 0.0 0.13 12.7 0.0 1.2 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red SHS2_Rpb7-N PF03876.12 EIE80347.1 - 5.4e-11 42.4 0.1 1.5e-10 40.9 0.0 1.8 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Tir_receptor_N PF07490.6 EIE80347.1 - 0.37 10.3 1.8 0.53 9.8 0.1 1.8 2 0 0 2 2 2 0 Translocated intimin receptor (Tir) N-terminus Pap_E4 PF02711.9 EIE80347.1 - 1.8 9.4 6.3 4.1 8.2 0.0 2.2 2 0 0 2 2 2 0 E4 protein Ferritin PF00210.19 EIE80348.1 - 5.6e-17 61.8 1.1 7.3e-17 61.4 0.0 1.6 2 0 0 2 2 2 1 Ferritin-like domain HlyE PF06109.8 EIE80348.1 - 0.1 11.5 0.1 0.16 10.9 0.0 1.5 1 1 0 1 1 1 0 Haemolysin E (HlyE) DUF563 PF04577.9 EIE80349.1 - 3.3e-13 50.0 0.0 5.3e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) DHO_dh PF01180.16 EIE80349.1 - 0.037 12.9 0.0 0.037 12.9 0.0 1.2 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase LysM PF01476.15 EIE80351.1 - 1e-06 28.5 0.1 1.5e-06 27.9 0.1 1.3 1 0 0 1 1 1 1 LysM domain NUDIX PF00293.23 EIE80352.1 - 3.6e-20 71.9 0.0 4.4e-20 71.6 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain DUF2389 PF09493.5 EIE80352.1 - 0.08 13.2 0.2 0.22 11.7 0.1 1.7 1 1 0 1 1 1 0 Tryptophan-rich protein (DUF2389) Lipocalin_4 PF13648.1 EIE80352.1 - 0.089 13.4 0.0 2.9 8.5 0.0 2.2 2 1 0 2 2 2 0 Lipocalin-like domain FAR1 PF03101.10 EIE80354.1 - 1.5e-05 25.4 1.2 2.9e-05 24.5 0.8 1.4 1 0 0 1 1 1 1 FAR1 DNA-binding domain ALS2CR8 PF15299.1 EIE80354.1 - 0.0065 16.0 2.1 0.01 15.4 1.4 1.4 1 1 0 1 1 1 1 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 DPBB_1 PF03330.13 EIE80355.1 - 2.9e-05 23.9 0.6 0.00018 21.4 0.4 2.3 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EIE80355.1 - 0.0056 16.3 0.3 0.011 15.4 0.1 1.4 1 1 0 1 1 1 1 Barwin family RCC1 PF00415.13 EIE80356.1 - 9.8e-40 134.5 17.0 3.5e-10 39.9 0.0 8.1 7 2 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EIE80356.1 - 1e-28 98.2 37.6 1.2e-08 34.2 3.6 7.3 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat ApbA_C PF08546.6 EIE80357.1 - 6.5e-32 110.1 0.5 1.1e-31 109.4 0.4 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 EIE80357.1 - 5.4e-30 103.8 0.0 1.1e-29 102.8 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA GUCT PF08152.7 EIE80357.1 - 0.034 14.1 0.1 0.083 12.8 0.1 1.6 1 0 0 1 1 1 0 GUCT (NUC152) domain Ribosomal_S14 PF00253.16 EIE80358.1 - 5.8e-20 70.4 4.1 6.4e-20 70.2 2.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF4428 PF14471.1 EIE80358.1 - 0.053 13.2 0.1 0.065 12.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) DUF1451 PF07295.6 EIE80358.1 - 0.066 12.9 0.2 0.066 12.9 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1451) GTP_EFTU PF00009.22 EIE80360.1 - 6.4e-39 133.3 0.1 1e-38 132.7 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 EIE80360.1 - 2.4e-35 120.4 0.3 6.8e-35 118.9 0.2 1.8 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 EIE80360.1 - 7.4e-08 32.4 1.5 7.4e-08 32.4 1.1 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EIE80360.1 - 0.0076 16.2 0.0 0.016 15.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EIE80360.1 - 0.042 13.6 0.1 0.21 11.3 0.0 2.1 2 1 0 3 3 3 0 Dynamin family RNase_H2_suC PF08615.6 EIE80361.1 - 2.8e-15 56.3 0.9 5.5e-15 55.4 0.6 1.5 1 1 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Baculo_p33 PF05214.7 EIE80361.1 - 0.029 13.6 0.3 0.049 12.8 0.2 1.3 1 0 0 1 1 1 0 Baculovirus P33 RINGv PF12906.2 EIE80362.1 - 4e-09 36.3 1.4 4e-09 36.3 1.0 2.0 2 0 0 2 2 2 1 RING-variant domain DPBB_1 PF03330.13 EIE80363.1 - 2.4e-12 46.6 0.1 3.1e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EIE80363.1 - 6e-05 22.7 0.2 8e-05 22.3 0.1 1.2 1 0 0 1 1 1 1 Barwin family zinc_ribbon_2 PF13240.1 EIE80363.1 - 0.11 12.0 0.2 0.31 10.5 0.0 1.9 2 1 0 2 2 2 0 zinc-ribbon domain 2C_adapt PF08793.5 EIE80363.1 - 0.18 11.6 1.0 0.31 10.9 0.7 1.3 1 0 0 1 1 1 0 2-cysteine adaptor domain Fungal_trans PF04082.13 EIE80364.1 - 0.00097 18.0 0.5 0.00097 18.0 0.4 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIE80364.1 - 0.011 15.6 13.1 0.011 15.6 9.1 2.0 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1508 PF07411.7 EIE80364.1 - 0.027 13.8 0.0 0.056 12.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1508) Glyco_hydro_4C PF11975.3 EIE80364.1 - 0.23 11.2 4.0 1.7 8.3 1.0 2.3 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase C-terminal domain FliD_N PF02465.13 EIE80364.1 - 0.69 10.3 9.8 2.5 8.5 0.0 3.4 2 1 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus DUF1660 PF07874.6 EIE80364.1 - 0.73 10.1 5.0 2.7 8.3 3.5 2.0 1 0 0 1 1 1 0 Prophage protein (DUF1660) AAA PF00004.24 EIE80365.1 - 1.1e-43 148.5 0.0 1.8e-43 147.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EIE80365.1 - 2.5e-07 30.7 0.0 1.4e-06 28.3 0.0 2.2 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EIE80365.1 - 6.6e-07 29.1 0.2 1.7e-05 24.5 0.1 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EIE80365.1 - 2.8e-06 26.5 0.0 5.2e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EIE80365.1 - 3.5e-06 27.1 0.1 0.00014 21.9 0.0 2.5 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 EIE80365.1 - 3.9e-06 27.0 0.1 0.0012 18.9 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 EIE80365.1 - 0.00024 20.8 0.1 0.0005 19.7 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EIE80365.1 - 0.00028 21.7 1.1 0.00077 20.2 0.1 2.4 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.8 EIE80365.1 - 0.00034 19.6 0.0 0.00087 18.2 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 EIE80365.1 - 0.00089 19.1 0.0 0.004 17.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 EIE80365.1 - 0.0011 18.5 0.3 0.0022 17.5 0.2 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EIE80365.1 - 0.0014 17.8 0.0 0.0033 16.5 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 EIE80365.1 - 0.0016 18.2 0.0 0.0033 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 EIE80365.1 - 0.0026 16.5 0.0 0.0047 15.6 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus IstB_IS21 PF01695.12 EIE80365.1 - 0.003 17.0 0.1 0.0057 16.0 0.1 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.1 EIE80365.1 - 0.0041 17.4 0.0 0.015 15.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EIE80365.1 - 0.006 16.7 0.0 0.012 15.8 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_3 PF07726.6 EIE80365.1 - 0.0083 15.7 0.0 0.017 14.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EIE80365.1 - 0.011 14.8 0.2 0.027 13.5 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin AAA_25 PF13481.1 EIE80365.1 - 0.013 14.9 0.3 0.066 12.6 0.2 2.0 1 1 1 2 2 2 0 AAA domain Sigma54_activat PF00158.21 EIE80365.1 - 0.014 14.8 0.1 0.053 12.9 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_28 PF13521.1 EIE80365.1 - 0.019 14.9 0.0 0.038 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EIE80365.1 - 0.03 13.9 0.1 0.081 12.5 0.0 1.7 2 0 0 2 2 2 0 NACHT domain PhoH PF02562.11 EIE80365.1 - 0.032 13.4 0.0 0.056 12.6 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein KaiC PF06745.8 EIE80365.1 - 0.045 12.8 0.1 0.21 10.6 0.0 2.1 1 1 1 2 2 2 0 KaiC Parvo_NS1 PF01057.12 EIE80365.1 - 0.049 12.5 0.0 0.083 11.7 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 UPF0079 PF02367.12 EIE80365.1 - 0.051 13.1 0.0 0.092 12.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 ResIII PF04851.10 EIE80365.1 - 0.069 12.9 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Arch_ATPase PF01637.13 EIE80365.1 - 0.073 12.7 0.0 0.27 10.8 0.0 1.9 1 1 0 1 1 1 0 Archaeal ATPase Sigma54_activ_2 PF14532.1 EIE80365.1 - 0.11 12.5 0.0 0.27 11.2 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_30 PF13604.1 EIE80365.1 - 0.13 11.8 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 EIE80365.1 - 0.14 11.6 0.1 0.46 10.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain CHCH PF06747.8 EIE80366.1 - 2.8e-09 36.6 2.0 2.8e-09 36.6 1.4 2.5 2 1 0 2 2 2 2 CHCH domain Pet191_N PF10203.4 EIE80366.1 - 1.5 8.8 8.6 1.9 8.5 4.2 2.4 1 1 2 3 3 3 0 Cytochrome c oxidase assembly protein PET191 COX6B PF02297.12 EIE80366.1 - 4.6 7.3 10.5 0.73 9.8 1.0 2.2 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb Cmc1 PF08583.5 EIE80366.1 - 6.8 6.5 10.4 3.4 7.5 1.2 2.3 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like NTF2 PF02136.15 EIE80367.1 - 2.5e-06 27.8 0.0 1.9e-05 24.9 0.0 2.2 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain LRR_4 PF12799.2 EIE80367.1 - 0.00064 19.2 13.3 0.0014 18.2 4.4 3.5 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 EIE80367.1 - 0.045 13.3 0.2 0.12 11.9 0.1 1.6 1 0 0 1 1 1 0 Leucine-rich repeat LRR_8 PF13855.1 EIE80367.1 - 0.39 10.4 8.6 0.048 13.4 1.5 2.6 2 1 0 2 2 2 0 Leucine rich repeat Fructosamin_kin PF03881.9 EIE80368.1 - 1.9e-67 227.2 0.2 2.2e-67 227.0 0.1 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 EIE80368.1 - 4.6e-06 26.5 0.0 6e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 EIE80369.1 - 4.8e-72 242.2 0.0 2.5e-71 239.8 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE80369.1 - 1.3e-35 122.7 0.0 7e-33 113.7 0.0 3.4 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE80369.1 - 6e-07 28.7 1.1 0.019 13.9 0.0 2.7 2 1 0 2 2 2 2 Kinase-like RIO1 PF01163.17 EIE80369.1 - 0.00014 21.3 1.2 0.00032 20.0 0.8 1.6 1 0 0 1 1 1 1 RIO1 family GCIP PF13324.1 EIE80371.1 - 0.32 10.1 7.5 0.39 9.8 5.2 1.1 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting p450 PF00067.17 EIE80372.1 - 2.4e-80 270.3 0.0 3.3e-80 269.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FtsJ PF01728.14 EIE80373.1 - 6.3e-66 221.8 0.0 7.7e-66 221.5 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 EIE80373.1 - 0.0079 16.7 0.0 0.023 15.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Exo_endo_phos PF03372.18 EIE80373.1 - 0.046 13.6 0.0 0.064 13.1 0.0 1.2 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family CbiA PF01656.18 EIE80373.1 - 0.057 12.8 0.0 0.085 12.2 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Clp1 PF06807.9 EIE80373.1 - 0.12 12.0 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Pre-mRNA cleavage complex II protein Clp1 ETF PF01012.16 EIE80375.1 - 4.7e-38 130.4 3.3 8.3e-38 129.6 2.3 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.14 EIE80375.1 - 2.4e-29 100.7 2.8 3.1e-29 100.4 0.6 2.3 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain Mito_carr PF00153.22 EIE80376.1 - 1e-36 124.5 0.0 1.1e-21 76.3 0.0 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein Hexokinase_2 PF03727.11 EIE80377.1 - 2.4e-74 249.5 0.8 3.5e-74 249.0 0.5 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EIE80377.1 - 1.2e-68 230.5 0.0 2e-68 229.7 0.0 1.4 1 0 0 1 1 1 1 Hexokinase HhH-GPD PF00730.20 EIE80378.1 - 1.1e-10 41.7 0.0 1.3e-10 41.5 0.0 1.1 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EIE80378.1 - 0.013 15.1 0.0 0.032 13.9 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif HHH_5 PF14520.1 EIE80378.1 - 0.022 14.9 0.2 0.86 9.8 0.2 2.5 1 1 0 1 1 1 0 Helix-hairpin-helix domain Cdd1 PF11731.3 EIE80378.1 - 0.083 12.8 0.0 5.1 7.0 0.0 2.3 1 1 1 2 2 2 0 Pathogenicity locus EzrA PF06160.7 EIE80379.1 - 0.0019 16.5 0.4 0.0022 16.2 0.3 1.0 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA APG6 PF04111.7 EIE80379.1 - 0.0045 16.0 0.2 0.0052 15.8 0.1 1.0 1 0 0 1 1 1 1 Autophagy protein Apg6 MscS_porin PF12795.2 EIE80379.1 - 0.027 13.8 0.3 0.046 13.0 0.1 1.4 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain TMF_DNA_bd PF12329.3 EIE80379.1 - 0.09 12.5 2.1 0.34 10.7 1.1 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF342 PF03961.8 EIE80379.1 - 0.09 11.1 1.7 0.11 10.9 1.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Syntaxin-6_N PF09177.6 EIE80379.1 - 0.18 12.2 0.9 0.82 10.1 0.5 2.2 1 1 2 3 3 3 0 Syntaxin 6, N-terminal IncA PF04156.9 EIE80379.1 - 0.38 10.3 2.6 1.5 8.4 2.2 1.6 1 1 1 2 2 2 0 IncA protein Mito_carr PF00153.22 EIE80380.1 - 7.4e-30 102.5 2.7 9.9e-16 57.2 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein NMO PF03060.10 EIE80381.1 - 4e-66 223.4 0.6 5.1e-66 223.0 0.4 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EIE80381.1 - 2.2e-12 46.5 3.2 1.5e-07 30.6 0.3 2.7 1 1 2 3 3 3 2 IMP dehydrogenase / GMP reductase domain NanE PF04131.9 EIE80381.1 - 0.011 14.7 0.1 0.011 14.7 0.1 2.6 3 0 0 3 3 3 0 Putative N-acetylmannosamine-6-phosphate epimerase FMN_dh PF01070.13 EIE80381.1 - 0.012 14.5 1.0 0.022 13.6 0.7 1.4 1 0 0 1 1 1 0 FMN-dependent dehydrogenase Glu_synthase PF01645.12 EIE80381.1 - 0.016 14.1 1.2 0.022 13.6 0.2 1.6 2 0 0 2 2 2 0 Conserved region in glutamate synthase CBS PF00571.23 EIE80382.1 - 8.8e-31 105.4 2.3 1.4e-08 34.3 0.2 4.6 4 0 0 4 4 4 4 CBS domain Ribosomal_S5_C PF03719.10 EIE80383.1 - 1.5e-24 85.0 0.0 1.3e-23 82.0 0.0 2.2 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 EIE80383.1 - 2.8e-17 62.2 1.0 5.8e-17 61.1 0.7 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Fer4 PF00037.22 EIE80384.1 - 2.1e-14 52.3 16.5 1.5e-08 33.8 3.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 EIE80384.1 - 2.8e-12 46.8 10.8 4.2e-12 46.2 7.5 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.1 EIE80384.1 - 4.3e-10 39.2 3.9 8.1e-05 22.3 0.2 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.1 EIE80384.1 - 4.6e-10 40.0 6.7 0.00012 22.7 0.2 2.2 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.1 EIE80384.1 - 8.2e-10 38.3 22.8 5.2e-08 32.5 8.9 1.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 EIE80384.1 - 2.4e-09 37.3 11.1 4.1e-09 36.5 7.7 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 EIE80384.1 - 9.9e-09 35.1 29.2 1.2e-05 25.1 8.0 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_2 PF12797.2 EIE80384.1 - 1.5e-08 34.0 14.4 8.2e-05 22.3 1.8 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.2 EIE80384.1 - 6.3e-08 32.1 18.0 0.00064 19.4 3.4 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 EIE80384.1 - 3.1e-06 27.4 9.0 0.00043 20.5 7.5 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_4 PF12800.2 EIE80384.1 - 3.1e-06 27.0 12.6 0.00069 19.7 2.3 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_18 PF13746.1 EIE80384.1 - 1.2e-05 25.6 9.9 0.0089 16.4 0.7 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.1 EIE80384.1 - 5.7e-05 23.4 10.4 0.023 15.1 0.2 2.4 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_15 PF13459.1 EIE80384.1 - 0.0068 16.9 13.0 0.42 11.2 1.5 2.6 2 1 0 2 2 2 2 4Fe-4S single cluster domain Fer4_3 PF12798.2 EIE80384.1 - 0.033 14.7 18.1 0.069 13.7 3.2 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.5 EIE80384.1 - 0.13 12.3 5.7 0.32 11.1 0.1 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain GCR1_C PF12550.3 EIE80385.1 - 5e-26 90.3 0.7 4.7e-25 87.2 0.2 2.6 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes GCR1_C PF12550.3 EIE80386.1 - 5.1e-26 90.3 0.7 5.1e-25 87.1 0.2 2.6 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes LEA_2 PF03168.8 EIE80387.1 - 2.9e-06 27.5 0.0 4.2e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Late embryogenesis abundant protein zf-CCCH PF00642.19 EIE80389.1 - 4.6e-20 70.8 22.8 4.2e-12 45.4 1.9 3.0 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EIE80389.1 - 0.0076 16.2 15.2 0.079 12.9 0.6 3.2 3 1 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type Imm31 PF15595.1 EIE80389.1 - 0.027 14.2 1.3 0.049 13.4 0.9 1.4 1 0 0 1 1 1 0 Immunity protein 31 Mem_trans PF03547.13 EIE80389.1 - 0.17 10.1 1.1 0.2 9.9 0.8 1.1 1 0 0 1 1 1 0 Membrane transport protein DUF1510 PF07423.6 EIE80389.1 - 0.24 10.7 13.5 0.33 10.2 9.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) zf-CCHH PF10283.4 EIE80389.1 - 0.67 9.8 9.5 1.1 9.1 0.4 3.2 3 0 0 3 3 3 0 Zinc-finger (CX5CX6HX5H) motif Inhibitor_I78 PF11720.3 EIE80391.1 - 3.8e-11 42.5 0.1 4.4e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.13 EIE80391.1 - 0.0064 16.6 0.2 0.019 15.1 0.0 1.7 1 1 1 2 2 2 1 Potato inhibitor I family PPR_2 PF13041.1 EIE80392.1 - 1.4e-17 63.4 2.1 1.9e-09 37.3 0.3 2.6 2 1 1 3 3 3 3 PPR repeat family PPR_3 PF13812.1 EIE80392.1 - 2.6e-15 55.3 0.1 2.2e-08 33.7 0.0 3.1 3 0 0 3 3 3 3 Pentatricopeptide repeat domain PPR PF01535.15 EIE80392.1 - 3.9e-07 29.5 1.1 6e-06 25.8 0.1 2.8 3 1 0 3 3 3 1 PPR repeat PPR_1 PF12854.2 EIE80392.1 - 2.1e-05 23.8 0.0 0.026 14.0 0.0 2.4 2 0 0 2 2 2 2 PPR repeat RVT_1 PF00078.22 EIE80393.1 - 1.9e-05 24.1 0.0 3.5e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Band_7 PF01145.20 EIE80394.1 - 1.2e-19 70.8 0.1 2.2e-12 47.2 0.0 2.1 1 1 1 2 2 2 2 SPFH domain / Band 7 family Band_7_1 PF13421.1 EIE80394.1 - 0.001 18.6 0.1 0.0014 18.2 0.0 1.2 1 0 0 1 1 1 1 SPFH domain-Band 7 family SCF PF02404.10 EIE80394.1 - 0.015 14.5 0.1 0.021 14.0 0.1 1.2 1 0 0 1 1 1 0 Stem cell factor Band_7 PF01145.20 EIE80395.1 - 1.3e-28 100.0 0.7 1.9e-28 99.5 0.5 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 EIE80395.1 - 0.02 14.3 0.1 0.031 13.8 0.0 1.3 1 0 0 1 1 1 0 SPFH domain-Band 7 family Trp_syntA PF00290.15 EIE80396.1 - 4.4e-94 313.8 0.3 7.1e-94 313.1 0.0 1.4 2 0 0 2 2 2 1 Tryptophan synthase alpha chain PALP PF00291.20 EIE80396.1 - 5.6e-47 160.4 0.3 8.4e-47 159.8 0.2 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme His_biosynth PF00977.16 EIE80396.1 - 0.0087 15.3 0.1 0.019 14.2 0.1 1.5 1 0 0 1 1 1 1 Histidine biosynthesis protein UPF0220 PF05255.6 EIE80397.1 - 3.7e-05 23.0 0.1 0.13 11.4 0.0 2.0 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0220) zf-RING_4 PF14570.1 EIE80398.1 - 5.9e-22 76.9 12.1 1.3e-21 75.9 8.4 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.1 EIE80398.1 - 2.9e-06 26.8 8.4 6.4e-06 25.7 5.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_5 PF13893.1 EIE80398.1 - 2.1e-05 24.2 0.2 0.00014 21.6 0.2 2.3 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EIE80398.1 - 9.2e-05 22.0 0.0 0.0028 17.2 0.0 2.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_2 PF13639.1 EIE80398.1 - 0.00017 21.3 11.4 0.00037 20.2 7.9 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EIE80398.1 - 0.00093 19.1 12.1 0.0021 18.0 8.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIE80398.1 - 0.012 15.2 10.7 0.03 13.9 7.4 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.1 EIE80398.1 - 0.013 15.1 3.5 0.013 15.1 2.4 2.2 2 0 0 2 2 2 0 Zinc-binding RING-finger Baculo_IE-1 PF05290.6 EIE80398.1 - 0.015 15.0 3.0 0.035 13.8 2.1 1.5 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Nup35_RRM PF05172.8 EIE80398.1 - 0.061 13.0 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF3245 PF11595.3 EIE80398.1 - 2.1 8.6 17.4 1.4 9.1 3.4 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3245) zf-RING_5 PF14634.1 EIE80398.1 - 2.8 7.7 10.0 6 6.6 7.0 1.6 1 0 0 1 1 1 0 zinc-RING finger domain Gastrin PF00918.12 EIE80398.1 - 9.1 7.1 10.7 9.8 7.0 4.0 2.5 2 0 0 2 2 2 0 Gastrin/cholecystokinin family LRR_7 PF13504.1 EIE80399.1 - 0.0039 17.1 1.0 18 6.0 0.0 5.4 5 0 0 5 5 5 1 Leucine rich repeat LRR_8 PF13855.1 EIE80399.1 - 0.039 13.7 2.8 0.88 9.3 0.0 4.3 6 0 0 6 6 6 0 Leucine rich repeat ABC2_membrane PF01061.19 EIE80401.1 - 1.1e-85 286.1 56.8 7.6e-48 162.4 12.9 3.7 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.22 EIE80401.1 - 1.1e-36 126.1 1.7 2.1e-20 73.4 0.0 3.0 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.7 EIE80401.1 - 3.8e-29 100.3 5.8 1.8e-22 78.9 0.0 2.8 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.1 EIE80401.1 - 2e-08 34.1 0.0 5.2e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_21 PF13304.1 EIE80401.1 - 4.6e-07 30.0 0.0 0.17 11.8 0.0 3.5 3 0 0 3 3 3 2 AAA domain ABC2_membrane_3 PF12698.2 EIE80401.1 - 2e-06 27.1 61.1 0.00029 20.0 14.0 3.9 3 1 0 3 3 3 2 ABC-2 family transporter protein AAA_22 PF13401.1 EIE80401.1 - 1.6e-05 25.0 0.1 0.062 13.4 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EIE80401.1 - 8.1e-05 22.0 0.2 0.0071 15.7 0.2 2.8 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 EIE80401.1 - 0.00025 20.2 0.0 0.0036 16.4 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EIE80401.1 - 0.00044 19.7 1.4 0.01 15.3 0.2 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain cobW PF02492.14 EIE80401.1 - 0.00055 19.4 0.1 0.15 11.4 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.1 EIE80401.1 - 0.0034 17.3 0.0 0.93 9.4 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 EIE80401.1 - 0.0035 17.6 0.8 2 8.6 0.0 3.0 3 0 0 3 3 2 1 AAA domain UPF0079 PF02367.12 EIE80401.1 - 0.0055 16.3 1.9 0.41 10.2 0.3 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_17 PF13207.1 EIE80401.1 - 0.0066 17.2 0.0 1.4 9.7 0.0 3.0 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.4 EIE80401.1 - 0.008 15.6 0.7 1 8.8 0.1 2.3 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.1 EIE80401.1 - 0.019 14.8 0.0 0.78 9.6 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.1 EIE80401.1 - 0.02 14.6 1.5 6.8 6.5 0.2 2.6 2 0 0 2 2 2 0 Part of AAA domain NACHT PF05729.7 EIE80401.1 - 0.032 13.8 0.4 2.5 7.7 0.2 2.4 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.1 EIE80401.1 - 0.04 13.8 2.6 0.37 10.7 0.2 2.7 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 EIE80401.1 - 0.064 13.4 0.6 21 5.3 0.1 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.1 EIE80401.1 - 0.075 12.9 0.0 0.42 10.5 0.0 2.3 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Miro PF08477.8 EIE80401.1 - 0.1 13.1 0.0 5.1 7.6 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein MMR_HSR1 PF01926.18 EIE80401.1 - 0.23 11.4 1.0 24 4.9 0.0 3.1 3 0 0 3 3 2 0 50S ribosome-binding GTPase AAA_30 PF13604.1 EIE80401.1 - 0.42 10.1 4.1 4 6.9 0.1 2.9 3 0 0 3 3 2 0 AAA domain PDR_assoc PF08370.6 EIE80401.1 - 7 6.2 11.4 0.097 12.1 0.2 3.5 3 0 0 3 3 3 0 Plant PDR ABC transporter associated ABC_tran PF00005.22 EIE80402.1 - 3.1e-43 147.3 10.6 1.5e-23 83.6 0.0 4.9 4 1 0 4 4 4 2 ABC transporter AAA_21 PF13304.1 EIE80402.1 - 3e-17 63.4 14.6 9.4e-06 25.7 0.0 5.2 3 2 1 4 4 4 3 AAA domain SMC_N PF02463.14 EIE80402.1 - 9.6e-11 41.3 11.1 0.00028 20.1 0.0 4.5 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 EIE80402.1 - 5.4e-09 35.4 0.0 0.00059 19.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 EIE80402.1 - 2.1e-07 31.1 0.6 0.00093 19.3 0.1 3.8 3 1 0 3 3 3 1 AAA domain NACHT PF05729.7 EIE80402.1 - 4e-07 29.8 0.0 0.013 15.1 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA PF00004.24 EIE80402.1 - 4.9e-07 30.0 0.0 0.023 14.9 0.0 3.8 4 1 0 4 4 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EIE80402.1 - 1.7e-06 28.8 5.6 0.042 14.6 0.0 4.0 5 0 0 5 5 4 2 AAA domain DAP3 PF10236.4 EIE80402.1 - 2.2e-06 26.8 0.1 0.0066 15.4 0.0 2.9 3 0 0 3 3 3 2 Mitochondrial ribosomal death-associated protein 3 Arch_ATPase PF01637.13 EIE80402.1 - 1.2e-05 25.1 3.6 0.043 13.5 0.0 4.1 3 2 1 4 4 4 2 Archaeal ATPase AAA_28 PF13521.1 EIE80402.1 - 1.4e-05 25.0 0.0 0.00028 20.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EIE80402.1 - 1.8e-05 24.8 0.5 0.14 12.1 0.0 3.6 2 2 0 2 2 2 2 AAA ATPase domain ABC_tran_2 PF12848.2 EIE80402.1 - 2.5e-05 24.0 7.4 2.5e-05 24.0 5.1 2.2 2 0 0 2 2 1 1 ABC transporter AAA_14 PF13173.1 EIE80402.1 - 3.7e-05 23.6 1.1 0.45 10.4 0.0 4.3 5 0 0 5 5 4 2 AAA domain AAA_33 PF13671.1 EIE80402.1 - 8.4e-05 22.4 0.8 0.04 13.7 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 EIE80402.1 - 9.9e-05 21.7 0.0 0.16 11.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RNA_helicase PF00910.17 EIE80402.1 - 0.00012 22.1 2.7 0.26 11.4 0.0 3.8 4 0 0 4 4 3 2 RNA helicase MMR_HSR1 PF01926.18 EIE80402.1 - 0.00018 21.4 2.1 0.064 13.2 0.0 3.6 3 1 0 3 3 3 1 50S ribosome-binding GTPase Miro PF08477.8 EIE80402.1 - 0.00028 21.3 0.0 0.59 10.6 0.0 3.2 2 0 0 2 2 2 1 Miro-like protein AAA_5 PF07728.9 EIE80402.1 - 0.00051 19.7 0.1 0.28 10.8 0.0 3.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EIE80402.1 - 0.0014 18.0 0.2 0.26 10.6 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_10 PF12846.2 EIE80402.1 - 0.0029 17.1 0.4 0.65 9.3 0.0 2.9 4 0 0 4 4 3 1 AAA-like domain MobB PF03205.9 EIE80402.1 - 0.0039 16.9 0.4 0.22 11.2 0.0 3.0 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.1 EIE80402.1 - 0.0064 16.0 0.9 1.8 8.0 0.0 3.3 3 0 0 3 3 3 1 AAA domain PduV-EutP PF10662.4 EIE80402.1 - 0.012 15.1 0.2 0.089 12.2 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.13 EIE80402.1 - 0.012 14.8 3.3 0.092 12.0 0.0 3.2 3 0 0 3 3 3 0 Ferrous iron transport protein B AAA_23 PF13476.1 EIE80402.1 - 0.016 15.5 0.2 0.016 15.5 0.1 4.5 3 1 0 3 3 1 0 AAA domain AAA_18 PF13238.1 EIE80402.1 - 0.018 15.3 10.9 0.13 12.5 0.0 4.4 5 1 0 5 5 5 0 AAA domain SbcCD_C PF13558.1 EIE80402.1 - 0.04 13.8 0.0 3.4 7.6 0.0 3.0 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Thymidylate_kin PF02223.12 EIE80402.1 - 0.054 12.8 3.5 5.5 6.3 0.7 3.1 3 0 0 3 3 2 0 Thymidylate kinase Arf PF00025.16 EIE80402.1 - 0.077 12.2 4.5 0.22 10.7 0.0 2.9 3 0 0 3 3 3 0 ADP-ribosylation factor family RNB PF00773.14 EIE80403.1 - 1e-36 126.8 0.0 1.4e-36 126.4 0.0 1.2 1 0 0 1 1 1 1 RNB domain HLH PF00010.21 EIE80404.1 - 7.6e-06 25.5 0.2 6.1e-05 22.6 0.1 2.3 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Myosin_tail_1 PF01576.14 EIE80404.1 - 0.022 12.5 2.4 0.029 12.1 1.7 1.1 1 0 0 1 1 1 0 Myosin tail Hanta_nucleocap PF00846.13 EIE80404.1 - 0.027 13.1 0.1 0.036 12.7 0.1 1.1 1 0 0 1 1 1 0 Hantavirus nucleocapsid protein Med15_fungi PF05397.7 EIE80404.1 - 0.043 13.7 0.3 0.072 13.0 0.2 1.4 1 0 0 1 1 1 0 Mediator complex subunit 15 DUF2981 PF11200.3 EIE80404.1 - 0.092 11.8 1.3 0.11 11.6 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2981) DivIC PF04977.10 EIE80405.1 - 0.0018 17.6 0.1 0.003 16.9 0.0 1.3 1 0 0 1 1 1 1 Septum formation initiator SlyX PF04102.7 EIE80405.1 - 0.02 15.2 0.2 0.064 13.6 0.2 1.9 1 0 0 1 1 1 0 SlyX Rab5-bind PF09311.6 EIE80405.1 - 0.035 14.0 0.2 0.067 13.0 0.2 1.4 1 0 0 1 1 1 0 Rabaptin-like protein DUF1192 PF06698.6 EIE80405.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) TMF_TATA_bd PF12325.3 EIE80405.1 - 0.12 12.1 0.1 0.26 11.0 0.1 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding O-FucT PF10250.4 EIE80409.1 - 2e-15 56.7 0.6 9.5e-13 47.9 0.1 2.7 2 1 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase HTH_Tnp_Tc5 PF03221.11 EIE80409.1 - 0.05 13.4 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain bZIP_1 PF00170.16 EIE80410.1 - 5.3e-13 48.7 12.1 5.3e-13 48.7 8.4 2.6 3 0 0 3 3 3 1 bZIP transcription factor bZIP_2 PF07716.10 EIE80410.1 - 7.7e-13 48.0 11.4 7.7e-13 48.0 7.9 2.9 3 0 0 3 3 3 1 Basic region leucine zipper bZIP_Maf PF03131.12 EIE80410.1 - 9.7e-06 25.7 5.2 9.7e-06 25.7 3.6 2.4 2 0 0 2 2 2 1 bZIP Maf transcription factor TSC22 PF01166.13 EIE80410.1 - 0.0062 16.4 2.1 0.0062 16.4 1.4 2.9 3 0 0 3 3 3 1 TSC-22/dip/bun family Cep57_MT_bd PF06657.8 EIE80410.1 - 0.0076 16.1 0.4 0.025 14.5 0.3 1.9 1 0 0 1 1 1 1 Centrosome microtubule-binding domain of Cep57 DUF2353 PF09789.4 EIE80410.1 - 0.018 14.2 12.4 0.032 13.5 4.8 2.0 2 0 0 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) FAD-oxidase_C PF02913.14 EIE80410.1 - 0.041 13.1 0.0 0.062 12.6 0.0 1.3 1 0 0 1 1 1 0 FAD linked oxidases, C-terminal domain HALZ PF02183.13 EIE80410.1 - 1.7 8.4 10.9 0.25 11.0 0.8 3.2 4 0 0 4 4 4 0 Homeobox associated leucine zipper SID-1_RNA_chan PF13965.1 EIE80410.1 - 2.5 6.1 6.1 3.1 5.8 4.3 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF972 PF06156.8 EIE80410.1 - 6.9 7.0 14.6 0.52 10.6 1.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF972) HLH PF00010.21 EIE80412.1 - 5.4e-18 64.4 0.4 5.4e-18 64.4 0.3 3.1 3 1 0 3 3 3 1 Helix-loop-helix DNA-binding domain MIR PF02815.14 EIE80413.1 - 4.5e-16 58.9 0.5 3.6e-12 46.2 0.1 2.3 1 1 1 2 2 2 2 MIR domain Ins145_P3_rec PF08709.6 EIE80413.1 - 1.4e-10 40.5 0.1 3.3e-08 32.8 0.0 2.1 1 1 0 2 2 2 2 Inositol 1,4,5-trisphosphate/ryanodine receptor MFS_1 PF07690.11 EIE80414.1 - 7.1e-29 100.6 30.8 7.1e-29 100.6 21.3 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily WD40 PF00400.27 EIE80415.1 - 2.3e-45 150.9 15.2 1.5e-11 43.6 0.0 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat TFIID_90kDa PF04494.10 EIE80415.1 - 9.4e-11 41.9 1.1 3.9e-06 26.9 0.2 2.6 1 1 1 2 2 2 2 WD40 associated region in TFIID subunit Nup160 PF11715.3 EIE80415.1 - 0.011 13.9 4.3 0.91 7.5 0.1 2.8 3 1 1 4 4 4 0 Nucleoporin Nup120/160 eIF2A PF08662.6 EIE80415.1 - 0.036 13.7 0.1 1.1 8.9 0.0 3.0 1 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A LisH PF08513.6 EIE80415.1 - 0.048 13.4 0.2 0.2 11.4 0.0 2.2 2 0 0 2 2 2 0 LisH Abhydrolase_6 PF12697.2 EIE80416.1 - 6.1e-40 137.5 0.0 7.5e-40 137.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIE80416.1 - 4.8e-29 101.5 0.0 1.2e-28 100.2 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIE80416.1 - 2.8e-13 49.8 0.0 4.7e-13 49.1 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EIE80416.1 - 6.7e-05 22.6 0.0 0.00012 21.8 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase DLH PF01738.13 EIE80416.1 - 0.0002 20.7 0.0 0.14 11.4 0.0 2.4 2 1 0 2 2 2 2 Dienelactone hydrolase family EHN PF06441.7 EIE80416.1 - 0.00035 20.4 0.0 0.0029 17.5 0.0 2.2 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Ndr PF03096.9 EIE80416.1 - 0.0012 17.3 0.0 0.0022 16.5 0.0 1.3 1 0 0 1 1 1 1 Ndr family Abhydrolase_4 PF08386.5 EIE80416.1 - 0.014 15.3 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein PGAP1 PF07819.8 EIE80416.1 - 0.024 14.2 0.0 0.037 13.6 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Peptidase_S9 PF00326.16 EIE80416.1 - 0.026 13.7 0.1 3.7 6.7 0.0 3.0 2 1 1 3 3 3 0 Prolyl oligopeptidase family Rieske PF00355.21 EIE80417.1 - 7.8e-09 34.9 0.2 2.2e-08 33.5 0.1 1.8 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain Methyltransf_4 PF02390.12 EIE80418.1 - 1.7e-41 141.4 0.0 2.3e-41 140.9 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EIE80418.1 - 0.00016 22.2 0.0 0.00022 21.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIE80418.1 - 0.00074 19.8 0.0 0.0014 18.9 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIE80418.1 - 0.0089 15.6 0.0 0.012 15.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIE80418.1 - 0.013 15.9 0.0 0.025 15.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EIE80418.1 - 0.097 12.0 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain DOT1 PF08123.8 EIE80418.1 - 0.098 11.9 0.0 0.28 10.4 0.0 1.7 1 1 1 2 2 2 0 Histone methylation protein DOT1 Methyltransf_12 PF08242.7 EIE80418.1 - 0.1 13.1 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DSBA PF01323.15 EIE80420.1 - 2.9e-34 118.3 0.0 3.2e-34 118.1 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_3 PF13192.1 EIE80420.1 - 0.0039 16.9 0.1 0.058 13.2 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin domain DUF2703 PF10865.3 EIE80420.1 - 0.04 13.8 0.0 0.064 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2703) Thioredoxin_2 PF13098.1 EIE80420.1 - 0.064 13.4 0.1 0.55 10.4 0.1 2.1 1 1 0 1 1 1 0 Thioredoxin-like domain Ribosomal_S24e PF01282.14 EIE80421.1 - 7e-36 121.9 0.4 1.1e-35 121.3 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein S24e Ribosomal_S2 PF00318.15 EIE80421.1 - 0.12 11.5 0.6 0.14 11.3 0.4 1.1 1 0 0 1 1 1 0 Ribosomal protein S2 p450 PF00067.17 EIE80422.1 - 1.8e-86 290.4 0.0 2.2e-86 290.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GCR1_C PF12550.3 EIE80423.1 - 5.1e-26 90.3 0.7 5.1e-25 87.1 0.2 2.6 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes GCR1_C PF12550.3 EIE80424.1 - 5.1e-26 90.3 0.7 5.1e-25 87.1 0.2 2.6 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes HTH_Tnp_Tc3_2 PF01498.13 EIE80428.1 - 5.2e-14 52.0 1.1 1.1e-13 50.9 0.8 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.1 EIE80428.1 - 2.1e-09 37.2 0.2 2e-07 30.8 0.0 2.4 1 1 1 2 2 2 2 DDE superfamily endonuclease HTH_29 PF13551.1 EIE80428.1 - 0.0015 18.6 0.7 0.0067 16.5 0.0 2.2 1 1 1 2 2 2 1 Winged helix-turn helix DUF273 PF03314.9 EIE80428.1 - 0.042 13.1 0.2 0.059 12.6 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF273 p450 PF00067.17 EIE80429.1 - 1.8e-86 290.4 0.0 2.2e-86 290.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Aldo_ket_red PF00248.16 EIE80431.1 - 1.3e-59 201.3 0.0 1.5e-59 201.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF1394 PF07159.7 EIE80432.1 - 5.6e-88 294.9 0.6 6.4e-88 294.7 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) Ras PF00071.17 EIE80433.1 - 6.3e-56 188.2 0.1 7.2e-56 188.0 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIE80433.1 - 1e-19 71.1 0.0 1.4e-19 70.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIE80433.1 - 1.6e-07 30.7 0.0 2.1e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EIE80433.1 - 6.3e-05 22.4 0.3 0.00031 20.2 0.2 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EIE80433.1 - 0.00063 19.6 0.0 0.0008 19.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EIE80433.1 - 0.017 14.3 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region FeoB_N PF02421.13 EIE80433.1 - 0.036 13.3 0.6 0.17 11.1 0.4 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_25 PF13481.1 EIE80433.1 - 0.042 13.2 0.1 0.098 12.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain CbiA PF01656.18 EIE80433.1 - 0.15 11.4 0.1 0.31 10.4 0.1 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain eIF2A PF08662.6 EIE80434.1 - 1.7e-84 282.3 1.6 3e-81 271.7 0.0 2.7 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 EIE80434.1 - 0.034 12.9 0.5 14 4.3 0.0 2.9 2 1 1 3 3 3 0 Coatomer WD associated region V-SNARE PF05008.10 EIE80434.1 - 0.035 14.2 5.5 0.068 13.3 3.8 1.4 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus COX4 PF02936.9 EIE80435.1 - 9.7e-37 125.8 0.0 1.1e-36 125.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF1138 PF06592.8 EIE80435.1 - 0.091 12.7 0.1 0.2 11.6 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1138) Drf_GBD PF06371.8 EIE80436.1 - 1.4e-32 112.6 0.1 1.9e-32 112.1 0.1 1.1 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain FH2 PF02181.18 EIE80437.1 - 7.6e-67 225.7 24.6 1.1e-58 198.9 6.8 3.7 2 1 1 3 3 3 2 Formin Homology 2 Domain Sec16_C PF12931.2 EIE80437.1 - 2.9e-40 138.8 0.1 1e-39 137.0 0.0 2.0 2 0 0 2 2 2 1 Sec23-binding domain of Sec16 Drf_FH3 PF06367.11 EIE80437.1 - 1e-37 129.4 4.2 1e-37 129.4 2.9 2.8 3 0 0 3 3 3 1 Diaphanous FH3 Domain Sec16 PF12932.2 EIE80437.1 - 0.00095 19.1 0.1 0.0076 16.1 0.0 2.7 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region DZR PF12773.2 EIE80437.1 - 0.0044 16.8 1.1 0.011 15.5 0.8 1.6 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.1 EIE80437.1 - 1.5 8.4 8.5 1.9 8.1 5.0 1.9 2 0 0 2 2 2 0 zinc-ribbon domain SQS_PSY PF00494.14 EIE80439.1 - 2e-37 128.9 0.0 2.5e-37 128.6 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase DPBB_1 PF03330.13 EIE80440.1 - 6e-15 55.0 0.2 6e-15 55.0 0.2 3.1 4 1 0 4 4 4 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EIE80440.1 - 1e-05 25.2 2.3 1e-05 25.2 1.6 2.1 1 1 1 2 2 2 1 Barwin family Tom37_C PF11801.3 EIE80440.1 - 0.016 15.0 0.9 0.026 14.4 0.6 1.3 1 0 0 1 1 1 0 Tom37 C-terminal domain PcfJ PF14284.1 EIE80440.1 - 0.038 13.4 5.5 0.07 12.6 3.8 1.4 1 0 0 1 1 1 0 PcfJ-like protein NifU PF01106.12 EIE80440.1 - 0.084 12.6 0.1 0.24 11.1 0.1 1.8 1 0 0 1 1 1 0 NifU-like domain FAM176 PF14851.1 EIE80440.1 - 0.18 11.4 0.9 0.38 10.4 0.6 1.5 1 0 0 1 1 1 0 FAM176 family PH_10 PF15411.1 EIE80440.1 - 1.6 8.9 10.9 16 5.6 0.1 2.4 2 0 0 2 2 2 0 Pleckstrin homology domain BLVR PF06375.6 EIE80440.1 - 2.7 7.8 13.2 5.6 6.7 9.1 1.6 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) CxxCxxCC PF03692.10 EIE80440.1 - 6.4 7.3 7.9 2.9 8.4 1.9 3.0 1 1 2 3 3 3 0 Putative zinc- or iron-chelating domain Peptidase_S49_N PF08496.5 EIE80440.1 - 7 6.4 8.9 16 5.2 6.2 1.7 1 0 0 1 1 1 0 Peptidase family S49 N-terminal bZIP_2 PF07716.10 EIE80441.1 - 3.5e-09 36.3 12.1 3.5e-09 36.3 8.4 2.3 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 EIE80441.1 - 9.5e-09 35.0 17.0 9.5e-09 35.0 11.8 2.0 1 1 0 1 1 1 1 bZIP transcription factor NAM-associated PF14303.1 EIE80441.1 - 0.035 14.4 11.7 0.047 14.0 8.1 1.1 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain ORF6C PF10552.4 EIE80441.1 - 0.062 13.0 2.7 0.062 13.0 1.3 1.5 1 1 0 1 1 1 0 ORF6C domain bZIP_Maf PF03131.12 EIE80441.1 - 0.064 13.5 13.8 0.066 13.5 8.9 1.5 1 1 0 1 1 1 0 bZIP Maf transcription factor AAA_23 PF13476.1 EIE80441.1 - 1.6 9.0 9.5 2 8.6 6.6 1.1 1 0 0 1 1 1 0 AAA domain LURAP PF14854.1 EIE80442.1 - 0.0096 15.6 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 1 Leucine rich adaptor protein Epimerase PF01370.16 EIE80443.1 - 9.4e-52 175.7 0.0 1.1e-51 175.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 EIE80443.1 - 2.5e-24 84.9 0.1 4.7e-24 84.0 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 EIE80443.1 - 2.1e-17 62.7 0.0 4.8e-17 61.5 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EIE80443.1 - 7.4e-15 54.6 0.2 1.6e-14 53.4 0.1 1.7 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EIE80443.1 - 1.2e-12 48.0 0.0 1.9e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 EIE80443.1 - 1.3e-10 40.6 0.0 2e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 EIE80443.1 - 6.8e-09 35.0 0.0 4.9e-08 32.2 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein KR PF08659.5 EIE80443.1 - 1.4e-08 34.5 0.0 2.6e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EIE80443.1 - 1.3e-06 28.5 0.0 2.7e-06 27.5 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EIE80443.1 - 0.00026 20.3 0.2 0.00062 19.0 0.1 1.6 2 0 0 2 2 2 1 NmrA-like family 3HCDH_N PF02737.13 EIE80443.1 - 0.045 13.3 0.0 0.07 12.7 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 EIE80443.1 - 0.054 12.8 0.1 0.096 12.0 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Arylsulfotran_2 PF14269.1 EIE80443.1 - 0.14 11.3 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Arylsulfotransferase (ASST) JAB PF01398.16 EIE80444.1 - 4.9e-31 106.8 0.1 9.4e-31 105.9 0.1 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 EIE80444.1 - 0.00016 21.1 0.0 0.0003 20.3 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.8 EIE80444.1 - 0.0054 16.2 0.1 0.013 14.9 0.1 2.0 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0172) Cellulase PF00150.13 EIE80445.1 - 1.5e-14 53.9 0.6 2.4e-14 53.1 0.4 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) SecE PF00584.15 EIE80447.1 - 6.7e-13 48.0 0.0 8.3e-13 47.7 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex PAC2 PF09754.4 EIE80448.1 - 0.011 15.5 0.0 0.015 15.2 0.0 1.1 1 0 0 1 1 1 0 PAC2 family DUF1770 PF08589.5 EIE80449.1 - 0.026 15.1 0.0 0.035 14.7 0.0 1.3 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1770) DAHP_synth_1 PF00793.15 EIE80450.1 - 8.2e-80 267.3 0.0 9.3e-80 267.1 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family RNA_pol_A_bac PF01000.21 EIE80451.1 - 4e-29 101.0 0.0 6.1e-29 100.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EIE80451.1 - 2.5e-09 36.1 0.0 2.7e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Glyco_transf_17 PF04724.8 EIE80452.1 - 3.8e-69 233.3 0.2 4.8e-69 233.0 0.1 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 17 DUF1967 PF09269.6 EIE80452.1 - 0.055 13.1 0.1 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1967) Kinesin PF00225.18 EIE80453.1 - 9.1e-112 373.0 0.5 9.1e-112 373.0 0.4 2.6 2 1 0 2 2 2 1 Kinesin motor domain CUT PF02376.10 EIE80454.1 - 0.081 12.7 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 CUT domain YL1 PF05764.8 EIE80454.1 - 1.4 8.4 10.9 2.2 7.8 7.6 1.5 1 0 0 1 1 1 0 YL1 nuclear protein Chitin_synth_2 PF03142.10 EIE80455.1 - 2.6e-78 263.7 3.5 3.1e-78 263.4 2.5 1.1 1 0 0 1 1 1 1 Chitin synthase DEK_C PF08766.6 EIE80455.1 - 4e-06 26.5 0.9 0.00098 18.8 0.8 2.5 2 0 0 2 2 2 2 DEK C terminal domain TIP39 PF14980.1 EIE80455.1 - 0.0085 15.7 0.2 3.3 7.4 0.2 2.3 2 0 0 2 2 2 2 TIP39 peptide Glyco_trans_2_3 PF13632.1 EIE80455.1 - 0.048 13.3 9.0 0.23 11.1 6.2 1.9 1 1 0 1 1 1 0 Glycosyl transferase family group 2 ecTbetaR2 PF08917.5 EIE80455.1 - 0.05 13.3 1.3 2.9 7.6 0.6 2.8 2 1 1 3 3 3 0 Transforming growth factor beta receptor 2 ectodomain Myosin_head PF00063.16 EIE80456.1 - 5.6e-102 341.9 12.9 1.1e-100 337.7 8.9 2.1 1 1 0 1 1 1 1 Myosin head (motor domain) AAA_14 PF13173.1 EIE80456.1 - 0.0016 18.3 0.0 0.0057 16.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EIE80456.1 - 0.0037 16.3 0.1 0.19 10.8 0.0 3.1 3 0 0 3 3 3 1 Zeta toxin AAA_18 PF13238.1 EIE80456.1 - 0.0041 17.4 0.9 0.023 15.0 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 EIE80456.1 - 0.011 15.9 0.0 0.05 13.7 0.0 2.2 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EIE80456.1 - 0.058 13.2 0.0 0.19 11.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EIE80456.1 - 0.08 12.4 0.0 0.21 11.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.1 EIE80456.1 - 0.088 13.6 0.9 0.35 11.6 0.0 2.6 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EIE80456.1 - 0.38 11.0 0.0 0.38 11.0 0.0 3.0 2 1 0 2 2 2 0 ABC transporter AAA_16 PF13191.1 EIE80456.1 - 0.72 9.8 4.1 0.97 9.3 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain Na_Ca_ex PF01699.19 EIE80457.1 - 7.9e-24 83.8 30.7 2e-13 50.1 0.6 3.7 4 0 0 4 4 4 2 Sodium/calcium exchanger protein DUF307 PF03733.8 EIE80457.1 - 4.3e-09 36.6 9.0 4.3e-09 36.6 6.2 4.0 4 1 1 5 5 5 1 Domain of unknown function (DUF307) DUF2347 PF09804.4 EIE80457.1 - 0.05 12.8 0.7 0.09 12.0 0.5 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) DUF3661 PF12400.3 EIE80458.1 - 8.1e-35 119.7 12.2 8.1e-35 119.7 8.4 1.6 2 0 0 2 2 2 1 Vaculolar membrane protein SICA_beta PF12878.2 EIE80459.1 - 0.033 13.9 0.5 0.035 13.9 0.4 1.1 1 0 0 1 1 1 0 SICA extracellular beta domain Pneumo_matrix PF03393.11 EIE80459.1 - 0.54 9.1 3.5 0.58 9.0 2.4 1.0 1 0 0 1 1 1 0 Pneumovirus matrix protein HisKA_3 PF07730.8 EIE80460.1 - 0.014 15.7 0.3 0.046 14.0 0.1 2.0 1 1 1 2 2 2 0 Histidine kinase DUF1993 PF09351.5 EIE80460.1 - 0.052 13.4 1.1 0.068 13.0 0.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1993) PHP PF02811.14 EIE80460.1 - 0.076 12.8 1.2 0.089 12.5 0.8 1.2 1 0 0 1 1 1 0 PHP domain DUF87 PF01935.12 EIE80460.1 - 0.14 11.9 8.1 0.12 12.2 5.0 1.3 1 1 0 1 1 1 0 Domain of unknown function DUF87 MEDS PF14417.1 EIE80460.1 - 0.2 10.6 3.1 0.27 10.2 2.2 1.2 1 0 0 1 1 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain RNA_binding PF01877.12 EIE80460.1 - 0.34 10.9 5.8 0.14 12.1 1.9 2.0 2 1 0 2 2 2 0 RNA binding DUF1054 PF06335.7 EIE80460.1 - 0.35 10.4 7.0 1.8 8.1 0.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1054) Vip3A_N PF12495.3 EIE80460.1 - 0.37 10.4 6.1 1.3 8.6 0.6 2.2 1 1 1 2 2 2 0 Vegetative insecticide protein 3A N terminal APG6 PF04111.7 EIE80460.1 - 0.44 9.5 17.2 0.56 9.1 12.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 AAA_13 PF13166.1 EIE80460.1 - 0.86 7.9 15.0 1.2 7.5 10.4 1.1 1 0 0 1 1 1 0 AAA domain SpoU_sub_bind PF08032.7 EIE80460.1 - 0.93 9.7 4.2 0.47 10.6 1.0 1.8 2 0 0 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding RF-1 PF00472.15 EIE80460.1 - 1.2 8.9 13.3 0.53 10.1 1.6 2.4 1 1 1 2 2 2 0 RF-1 domain Muted PF14942.1 EIE80460.1 - 1.2 8.9 13.3 2.1 8.2 3.7 2.3 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein DUF2508 PF10704.4 EIE80460.1 - 1.2 9.3 13.6 0.069 13.3 1.3 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2508) CorA PF01544.13 EIE80460.1 - 2.1 7.2 8.9 4.4 6.2 6.2 1.5 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein CDC37_N PF03234.9 EIE80460.1 - 3.2 8.0 14.1 1.7 8.9 2.9 2.0 1 1 1 2 2 2 0 Cdc37 N terminal kinase binding DUF724 PF05266.9 EIE80460.1 - 3.4 7.2 16.0 59 3.2 11.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF724) DUF1664 PF07889.7 EIE80460.1 - 4.2 7.1 6.7 5.5 6.8 4.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) 5_3_exonuc PF01367.15 EIE80460.1 - 5.2 7.3 8.9 3.8 7.7 1.5 2.2 1 1 1 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF883 PF05957.8 EIE80460.1 - 6.1 7.3 8.2 2.2 8.7 1.0 2.6 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) GrpE PF01025.14 EIE80460.1 - 6.4 6.2 12.6 7.6 6.0 8.4 1.3 1 1 0 1 1 1 0 GrpE Exonuc_VII_L PF02601.10 EIE80460.1 - 7 5.7 13.4 8.2 5.5 9.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit 60KD_IMP PF02096.15 EIE80460.1 - 7.8 6.0 6.2 8.2 6.0 3.2 1.9 1 1 0 1 1 1 0 60Kd inner membrane protein Cu_amine_oxid PF01179.15 EIE80461.1 - 2.4e-167 556.8 2.2 3.2e-167 556.4 1.5 1.2 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 EIE80461.1 - 3.6e-18 65.4 0.1 8.9e-18 64.2 0.1 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 EIE80461.1 - 1.6e-14 53.7 0.0 3.4e-14 52.6 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain adh_short PF00106.20 EIE80462.1 - 2.2e-22 79.7 0.0 2.7e-22 79.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIE80462.1 - 8.6e-14 51.8 0.1 1.2e-13 51.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIE80462.1 - 1.2e-06 28.2 0.0 1.6e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 EIE80462.1 - 8.4e-05 21.8 0.0 0.0092 15.1 0.0 2.0 2 0 0 2 2 2 2 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 EIE80462.1 - 0.00067 19.7 0.1 0.00096 19.2 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 EIE80462.1 - 0.021 13.7 0.1 0.032 13.1 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain ADH_zinc_N PF00107.21 EIE80462.1 - 0.041 13.4 0.1 0.088 12.3 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Epimerase PF01370.16 EIE80462.1 - 0.044 13.1 0.0 0.056 12.8 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EIE80462.1 - 0.056 12.7 0.3 0.15 11.3 0.0 1.7 2 0 0 2 2 2 0 NmrA-like family Acetyltransf_CG PF14542.1 EIE80464.1 - 0.17 11.7 0.2 11 6.0 0.0 2.2 1 1 1 2 2 2 0 GCN5-related N-acetyl-transferase HSP70 PF00012.15 EIE80465.1 - 3.2e-242 804.7 12.3 3.6e-242 804.5 8.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EIE80465.1 - 2.6e-17 62.4 3.1 2.7e-16 59.1 1.5 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 EIE80465.1 - 0.00023 20.8 0.0 0.00054 19.6 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.5 EIE80465.1 - 0.0052 15.6 1.4 0.091 11.5 0.3 2.5 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain eIF3_N PF09440.5 EIE80465.1 - 0.0079 16.3 3.4 0.0079 16.3 2.3 1.8 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain Asp_decarbox PF02261.11 EIE80465.1 - 0.014 14.9 0.0 0.036 13.6 0.0 1.7 1 0 0 1 1 1 0 Aspartate decarboxylase FtsA PF14450.1 EIE80465.1 - 0.35 10.7 10.1 0.47 10.2 0.1 3.7 3 2 0 3 3 3 0 Cell division protein FtsA DUF4398 PF14346.1 EIE80465.1 - 3 7.9 11.2 2.1 8.4 1.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4398) DAHP_synth_1 PF00793.15 EIE80466.1 - 7e-90 300.4 0.0 1.7e-80 269.5 0.0 2.0 2 0 0 2 2 2 2 DAHP synthetase I family DDE_3 PF13358.1 EIE80467.1 - 5.6e-17 61.8 0.0 2.2e-16 59.9 0.0 1.7 1 1 0 1 1 1 1 DDE superfamily endonuclease Glucosamine_iso PF01182.15 EIE80468.1 - 2.7e-08 33.7 0.0 0.00027 20.6 0.0 2.3 1 1 1 2 2 2 2 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Tom22 PF04281.8 EIE80469.1 - 3.3e-36 123.8 4.7 9.4e-36 122.3 3.2 1.7 1 1 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 ABC2_membrane_2 PF12679.2 EIE80469.1 - 0.1 11.4 0.1 0.14 11.0 0.1 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein BSMAP PF12280.3 EIE80469.1 - 0.11 12.4 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Brain specific membrane anchored protein GvpG PF05120.7 EIE80469.1 - 0.56 10.0 0.1 0.56 10.0 0.1 2.7 3 0 0 3 3 3 0 Gas vesicle protein G ODC_AZ PF02100.12 EIE80470.1 - 2.8e-11 42.8 0.0 3e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme HORMA PF02301.13 EIE80471.1 - 0.21 11.0 2.3 1.8 7.9 1.5 1.9 1 1 1 2 2 2 0 HORMA domain MgsA_C PF12002.3 EIE80472.1 - 7.5e-49 165.6 0.2 1.1e-48 165.1 0.1 1.3 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA PF00004.24 EIE80472.1 - 5.1e-16 59.0 0.0 1.1e-15 57.9 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EIE80472.1 - 1e-10 41.0 0.0 1.4e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EIE80472.1 - 1.7e-07 31.0 0.0 1.2e-06 28.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EIE80472.1 - 1e-06 28.6 0.0 1.6e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 EIE80472.1 - 3.2e-06 26.7 0.0 0.00014 21.3 0.0 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_22 PF13401.1 EIE80472.1 - 6.5e-05 23.0 0.3 0.0066 16.5 0.2 2.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EIE80472.1 - 0.00016 22.5 0.2 0.00058 20.6 0.2 2.3 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EIE80472.1 - 0.00019 20.6 0.1 0.072 12.2 0.0 2.4 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EIE80472.1 - 0.00026 20.6 0.1 0.0026 17.4 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain AAA_18 PF13238.1 EIE80472.1 - 0.00027 21.2 0.0 0.00069 19.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EIE80472.1 - 0.00043 20.3 0.7 0.086 12.8 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain Sigma54_activ_2 PF14532.1 EIE80472.1 - 0.00081 19.4 0.0 0.0017 18.4 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain Viral_helicase1 PF01443.13 EIE80472.1 - 0.0011 18.5 0.0 0.0017 17.8 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_2 PF07724.9 EIE80472.1 - 0.0015 18.4 0.0 0.0026 17.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) ABC_tran PF00005.22 EIE80472.1 - 0.0027 18.0 0.0 0.0048 17.2 0.0 1.7 1 1 0 1 1 1 1 ABC transporter Rad17 PF03215.10 EIE80472.1 - 0.0038 15.9 0.1 0.0089 14.7 0.0 1.5 1 1 1 2 2 2 1 Rad17 cell cycle checkpoint protein ResIII PF04851.10 EIE80472.1 - 0.0047 16.7 0.4 1.2 8.9 0.0 2.4 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit RNA_helicase PF00910.17 EIE80472.1 - 0.0059 16.7 0.0 0.021 14.9 0.0 2.0 2 0 0 2 2 2 1 RNA helicase SKI PF01202.17 EIE80472.1 - 0.0074 16.1 0.1 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 Shikimate kinase Arch_ATPase PF01637.13 EIE80472.1 - 0.017 14.8 0.1 2.4 7.7 0.0 2.4 1 1 1 2 2 2 0 Archaeal ATPase AAA_11 PF13086.1 EIE80472.1 - 0.017 14.7 0.0 0.03 13.9 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_3 PF07726.6 EIE80472.1 - 0.034 13.7 0.0 0.089 12.3 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 EIE80472.1 - 0.04 13.3 0.2 7.3 5.9 0.0 2.6 2 1 1 3 3 3 0 AAA-like domain Zeta_toxin PF06414.7 EIE80472.1 - 0.045 12.8 0.0 0.1 11.7 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.1 EIE80472.1 - 0.055 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain CPT PF07931.7 EIE80472.1 - 0.066 12.8 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_24 PF13479.1 EIE80472.1 - 0.076 12.5 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EIE80472.1 - 0.086 12.4 0.0 0.27 10.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.12 EIE80472.1 - 0.12 11.1 0.1 5.1 5.8 0.0 2.5 1 1 1 2 2 2 0 Parvovirus non-structural protein NS1 NTPase_1 PF03266.10 EIE80472.1 - 0.17 11.5 0.3 1.1 8.8 0.0 2.3 2 1 0 2 2 2 0 NTPase CBFD_NFYB_HMF PF00808.18 EIE80473.1 - 5.4e-15 55.1 0.8 8.1e-15 54.6 0.5 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EIE80473.1 - 4.5e-09 36.2 0.1 6.9e-09 35.7 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 zf-H2C2_2 PF13465.1 EIE80474.1 - 6.6e-14 51.4 21.7 6.5e-07 29.3 3.9 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 EIE80474.1 - 4e-11 42.5 14.5 9.5e-06 25.6 1.0 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIE80474.1 - 5.1e-11 42.0 15.6 1.1e-05 25.3 1.7 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-BED PF02892.10 EIE80474.1 - 0.00014 21.5 5.3 0.002 17.8 0.9 2.3 1 1 1 2 2 2 1 BED zinc finger zf-C2H2_2 PF12756.2 EIE80474.1 - 0.00024 21.1 2.7 0.013 15.6 0.6 2.0 1 1 1 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 EIE80474.1 - 0.0029 17.6 4.8 0.1 12.7 1.1 2.3 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding DUF1644 PF07800.7 EIE80474.1 - 0.0099 15.7 2.9 0.011 15.6 2.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1644) DUF629 PF04780.7 EIE80474.1 - 0.011 14.3 1.6 0.06 11.8 0.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF629) zf-Di19 PF05605.7 EIE80474.1 - 0.031 14.3 6.2 0.11 12.6 4.3 1.8 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-Sec23_Sec24 PF04810.10 EIE80474.1 - 0.038 13.5 0.4 5.6 6.6 0.0 2.3 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger zf-RING_3 PF14369.1 EIE80474.1 - 0.039 13.9 1.2 4.5 7.3 0.0 2.3 2 0 0 2 2 2 0 zinc-finger DUF2225 PF09986.4 EIE80474.1 - 0.045 13.2 1.6 0.5 9.7 1.1 1.9 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-DBF PF07535.7 EIE80474.1 - 0.066 12.8 4.7 0.28 10.8 1.2 2.1 1 1 1 2 2 2 0 DBF zinc finger zf-C2H2_6 PF13912.1 EIE80474.1 - 0.11 12.4 1.6 0.11 12.4 1.1 2.7 2 1 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.2 EIE80474.1 - 0.12 12.6 6.3 0.78 10.0 1.7 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Prok-RING_4 PF14447.1 EIE80474.1 - 0.14 11.7 1.8 0.72 9.4 0.1 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-met2 PF12907.2 EIE80474.1 - 0.28 11.1 2.6 5.2 7.1 0.0 2.2 2 0 0 2 2 2 0 Zinc-binding Zn-ribbon_8 PF09723.5 EIE80474.1 - 0.39 10.7 3.0 4.7 7.2 0.1 2.2 1 1 1 2 2 2 0 Zinc ribbon domain GAGA PF09237.6 EIE80474.1 - 0.6 9.7 10.5 0.31 10.6 2.8 2.1 1 1 1 2 2 2 0 GAGA factor DUF3505 PF12013.3 EIE80474.1 - 0.95 9.7 4.8 0.36 11.0 0.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3505) FYVE PF01363.16 EIE80474.1 - 1.9 8.4 8.4 11 6.0 2.1 2.1 1 1 1 2 2 2 0 FYVE zinc finger zf-H2C2_5 PF13909.1 EIE80474.1 - 9.6 6.6 14.6 9.1 6.7 2.2 3.1 2 2 0 2 2 2 0 C2H2-type zinc-finger domain DUF2669 PF10876.3 EIE80475.1 - 0.14 11.8 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2669) HTH_Tnp_Tc3_2 PF01498.13 EIE80476.1 - 1.6e-16 60.0 1.1 3.5e-16 58.9 0.8 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.1 EIE80476.1 - 2.9e-16 59.5 0.0 5e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 EIE80476.1 - 2.3e-08 34.1 0.4 3.6e-07 30.3 0.0 2.7 3 0 0 3 3 3 1 Winged helix-turn helix HTH_23 PF13384.1 EIE80476.1 - 0.00016 21.2 0.1 0.00061 19.3 0.0 2.0 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.1 EIE80476.1 - 0.0018 18.2 0.0 0.0062 16.5 0.0 2.0 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_17 PF12728.2 EIE80476.1 - 0.0074 16.5 0.6 0.29 11.3 0.0 3.0 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_24 PF13412.1 EIE80476.1 - 0.011 15.1 0.0 0.14 11.5 0.0 2.5 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding HTH_38 PF13936.1 EIE80476.1 - 0.012 15.1 0.0 0.036 13.6 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_7 PF02796.10 EIE80476.1 - 0.046 13.5 0.4 1 9.2 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase SpoIIID PF12116.3 EIE80476.1 - 0.046 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Stage III sporulation protein D HTH_IclR PF09339.5 EIE80476.1 - 0.049 13.2 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain MerR PF00376.18 EIE80476.1 - 0.07 12.6 0.3 7.2 6.2 0.0 3.0 3 0 0 3 3 3 0 MerR family regulatory protein Apc5 PF12862.2 EIE80477.1 - 0.11 12.3 0.1 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 5 SHIPPO-rpt PF07004.7 EIE80480.1 - 0.0033 18.2 0.0 0.013 16.3 0.0 2.1 1 0 0 1 1 1 1 Sperm-tail PG-rich repeat Reo_sigmaC PF04582.7 EIE80480.1 - 0.078 12.1 13.6 0.061 12.4 0.2 3.2 1 1 1 3 3 3 0 Reovirus sigma C capsid protein Spc7 PF08317.6 EIE80480.1 - 6.6 5.2 50.5 3.5 6.1 9.7 3.3 1 1 3 4 4 4 0 Spc7 kinetochore protein PH PF00169.24 EIE80481.1 - 0.00018 21.6 0.4 0.00018 21.6 0.3 2.5 1 1 1 2 2 2 1 PH domain Acetyltransf_1 PF00583.19 EIE80482.1 - 1.3e-12 47.6 0.1 2e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EIE80482.1 - 3.2e-08 33.6 0.0 5.2e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.1 EIE80482.1 - 4e-07 30.0 0.0 5.5e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EIE80482.1 - 2.6e-06 27.6 0.1 3.9e-06 27.0 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EIE80482.1 - 5.1e-06 26.6 0.0 9e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EIE80482.1 - 0.00031 20.6 0.0 0.0015 18.3 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EIE80482.1 - 0.00035 20.3 0.0 0.00088 19.1 0.0 1.7 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 EIE80482.1 - 0.0031 17.2 0.0 0.0066 16.1 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein DUF2714 PF10896.3 EIE80482.1 - 0.024 14.4 2.5 0.046 13.5 1.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2714) DUF2156 PF09924.4 EIE80482.1 - 0.074 11.8 0.0 0.12 11.1 0.0 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2156) Ribosomal_L29 PF00831.18 EIE80483.1 - 2.1e-14 52.9 1.8 2.1e-14 52.9 1.2 2.0 2 1 0 2 2 2 1 Ribosomal L29 protein Ribosomal_S9 PF00380.14 EIE80483.1 - 0.28 11.4 3.2 0.48 10.6 2.2 1.5 1 1 0 1 1 1 0 Ribosomal protein S9/S16 DDE_3 PF13358.1 EIE80486.1 - 2e-28 99.0 0.0 3.6e-28 98.1 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.14 EIE80486.1 - 6.4e-05 22.1 0.0 0.0001 21.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 EIE80486.1 - 0.097 12.8 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix DUF740 PF05340.7 EIE80486.1 - 1.1 7.4 4.1 0.52 8.6 1.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF740) HTH_29 PF13551.1 EIE80487.1 - 7e-05 22.9 0.1 0.00012 22.1 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.1 EIE80487.1 - 0.017 15.1 0.0 0.048 13.6 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain DUF1804 PF08822.6 EIE80487.1 - 0.035 13.8 0.3 0.046 13.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1804) DDE_3 PF13358.1 EIE80487.1 - 0.041 13.6 0.2 0.6 9.8 0.0 2.3 2 1 0 2 2 2 0 DDE superfamily endonuclease DUF2145 PF09916.4 EIE80487.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2145) Ribosomal_S7 PF00177.16 EIE80488.1 - 1.4e-39 134.9 0.3 1.7e-39 134.7 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e HTH_Tnp_Tc3_2 PF01498.13 EIE80489.1 - 1.6e-16 60.0 1.1 3.5e-16 58.9 0.8 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.1 EIE80489.1 - 2.9e-16 59.5 0.0 5e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 EIE80489.1 - 2.3e-08 34.1 0.4 3.6e-07 30.3 0.0 2.7 3 0 0 3 3 3 1 Winged helix-turn helix HTH_23 PF13384.1 EIE80489.1 - 0.00016 21.2 0.1 0.00061 19.3 0.0 2.0 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.1 EIE80489.1 - 0.0018 18.2 0.0 0.0062 16.5 0.0 2.0 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_17 PF12728.2 EIE80489.1 - 0.0074 16.5 0.6 0.29 11.3 0.0 3.0 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_24 PF13412.1 EIE80489.1 - 0.011 15.1 0.0 0.14 11.5 0.0 2.5 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding HTH_38 PF13936.1 EIE80489.1 - 0.012 15.1 0.0 0.036 13.6 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_7 PF02796.10 EIE80489.1 - 0.046 13.5 0.4 1 9.2 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase SpoIIID PF12116.3 EIE80489.1 - 0.046 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Stage III sporulation protein D HTH_IclR PF09339.5 EIE80489.1 - 0.049 13.2 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain MerR PF00376.18 EIE80489.1 - 0.07 12.6 0.3 7.2 6.2 0.0 3.0 3 0 0 3 3 3 0 MerR family regulatory protein DAHP_synth_1 PF00793.15 EIE80490.1 - 3.1e-99 331.0 0.0 3.8e-99 330.7 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family CTK3 PF12243.3 EIE80492.1 - 1.8e-34 118.3 0.2 2.9e-34 117.6 0.1 1.3 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.3 EIE80492.1 - 4.8e-16 58.5 7.2 1.1e-15 57.3 5.0 1.6 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus DnaB_2 PF07261.6 EIE80492.1 - 0.011 15.3 0.3 0.077 12.6 0.0 2.3 2 0 0 2 2 2 0 Replication initiation and membrane attachment CbiX PF01903.12 EIE80492.1 - 0.076 13.1 0.7 0.55 10.3 0.0 2.5 2 2 2 4 4 4 0 CbiX Cauli_VI PF01693.11 EIE80493.1 - 2.9e-22 78.4 2.2 5.7e-22 77.4 1.5 1.5 1 0 0 1 1 1 1 Caulimovirus viroplasmin RNase_H PF00075.19 EIE80493.1 - 0.00019 21.7 0.7 0.00048 20.4 0.1 1.8 2 0 0 2 2 2 1 RNase H MORN PF02493.15 EIE80493.1 - 0.72 9.6 5.9 2.7 7.9 0.3 2.8 2 0 0 2 2 2 0 MORN repeat SET PF00856.23 EIE80494.1 - 7.7e-08 32.8 0.1 3.4e-06 27.4 0.1 2.2 1 1 1 2 2 2 2 SET domain DUF4313 PF14190.1 EIE80495.1 - 0.073 12.7 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4313) Myc_N PF01056.13 EIE80496.1 - 2.4 7.2 7.1 3.6 6.6 4.9 1.3 1 0 0 1 1 1 0 Myc amino-terminal region NTP_transf_2 PF01909.18 EIE80497.1 - 8.2e-13 48.5 0.0 2.4e-12 46.9 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.14 EIE80497.1 - 8e-09 35.3 0.9 2.6e-08 33.7 0.1 2.3 3 0 0 3 3 3 1 Cid1 family poly A polymerase adh_short PF00106.20 EIE80499.1 - 5.6e-20 71.9 0.0 7.4e-20 71.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIE80499.1 - 8.2e-11 42.1 0.0 9.9e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIE80499.1 - 4.6e-05 23.1 0.0 6.2e-05 22.7 0.0 1.3 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.5 EIE80499.1 - 0.00075 18.7 0.0 0.076 12.1 0.0 2.2 2 1 0 2 2 2 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 EIE80499.1 - 0.021 14.8 0.0 0.036 14.0 0.0 1.4 1 1 0 1 1 1 0 NADH(P)-binding Epimerase PF01370.16 EIE80499.1 - 0.05 13.0 0.0 0.068 12.5 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EIE80499.1 - 0.078 12.2 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Dak1_2 PF13684.1 EIE80499.1 - 0.079 11.8 0.1 0.11 11.3 0.1 1.2 1 0 0 1 1 1 0 Dihydroxyacetone kinase family RmlD_sub_bind PF04321.12 EIE80499.1 - 0.14 11.0 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain DUF2277 PF10041.4 EIE80499.1 - 0.17 11.8 0.2 18 5.4 0.0 2.9 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2277) DivIC PF04977.10 EIE80500.1 - 0.0035 16.7 0.9 0.0066 15.9 0.6 1.3 1 0 0 1 1 1 1 Septum formation initiator DUF4164 PF13747.1 EIE80500.1 - 0.016 15.3 1.6 1.1 9.3 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) SlyX PF04102.7 EIE80500.1 - 0.021 15.2 0.2 0.021 15.2 0.1 1.7 2 0 0 2 2 2 0 SlyX Rab5-bind PF09311.6 EIE80500.1 - 0.021 14.7 0.2 0.033 14.0 0.1 1.3 1 0 0 1 1 1 0 Rabaptin-like protein MCPVI PF02993.9 EIE80500.1 - 6 6.9 7.9 8.5 6.4 5.4 1.1 1 0 0 1 1 1 0 Minor capsid protein VI CBM_21 PF03370.8 EIE80502.1 - 1.8e-25 89.1 7.8 4.7e-25 87.7 5.4 1.7 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit CBM_25 PF03423.8 EIE80502.1 - 0.011 15.7 2.0 0.011 15.7 1.4 2.1 2 0 0 2 2 2 0 Carbohydrate binding domain (family 25) bZIP_C PF12498.3 EIE80502.1 - 2.4 9.4 7.1 0.83 10.9 2.6 2.0 2 0 0 2 2 2 0 Basic leucine-zipper C terminal STT3 PF02516.9 EIE80503.1 - 3e-135 451.9 38.3 1.6e-131 439.5 23.9 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit Peptidase_M50 PF02163.17 EIE80503.1 - 0.0096 14.8 4.6 3.9 6.3 2.5 3.2 1 1 1 3 3 3 2 Peptidase family M50 DUF1469 PF07332.6 EIE80503.1 - 9.7 5.9 0.0 9.7 5.9 0.0 4.9 4 2 2 6 6 6 0 Protein of unknown function (DUF1469) adh_short PF00106.20 EIE80504.1 - 1e-19 71.0 0.0 1.4e-19 70.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIE80504.1 - 2.6e-11 43.7 0.0 3.2e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIE80504.1 - 4.5e-05 23.1 0.0 6.9e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 EIE80504.1 - 0.0041 16.2 0.1 0.45 9.5 0.0 2.3 2 1 0 2 2 2 2 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 EIE80504.1 - 0.021 14.8 0.0 0.036 14.0 0.0 1.4 1 1 0 1 1 1 0 NADH(P)-binding Epimerase PF01370.16 EIE80504.1 - 0.038 13.4 0.0 0.06 12.7 0.0 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EIE80504.1 - 0.072 12.3 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family Dak1_2 PF13684.1 EIE80504.1 - 0.081 11.8 0.1 0.12 11.2 0.1 1.2 1 0 0 1 1 1 0 Dihydroxyacetone kinase family DUF2277 PF10041.4 EIE80504.1 - 0.16 11.9 0.2 18 5.4 0.0 2.9 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2277) adh_short PF00106.20 EIE80506.1 - 1e-19 71.0 0.0 1.4e-19 70.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIE80506.1 - 2.6e-11 43.7 0.0 3.2e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIE80506.1 - 4.5e-05 23.1 0.0 6.9e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 EIE80506.1 - 0.0041 16.2 0.1 0.45 9.5 0.0 2.3 2 1 0 2 2 2 2 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 EIE80506.1 - 0.021 14.8 0.0 0.036 14.0 0.0 1.4 1 1 0 1 1 1 0 NADH(P)-binding Epimerase PF01370.16 EIE80506.1 - 0.038 13.4 0.0 0.06 12.7 0.0 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EIE80506.1 - 0.072 12.3 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family Dak1_2 PF13684.1 EIE80506.1 - 0.081 11.8 0.1 0.12 11.2 0.1 1.2 1 0 0 1 1 1 0 Dihydroxyacetone kinase family DUF2277 PF10041.4 EIE80506.1 - 0.16 11.9 0.2 18 5.4 0.0 2.9 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2277) CwfJ_C_1 PF04677.10 EIE80507.1 - 2.1e-32 111.3 0.3 2.1e-32 111.3 0.2 1.6 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 EIE80507.1 - 4.2e-24 84.8 1.2 4.2e-24 84.8 0.8 2.6 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 SNase PF00565.12 EIE80509.1 - 2.4e-62 207.9 3.3 7.8e-21 74.3 0.0 5.2 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.19 EIE80509.1 - 1.6e-30 105.4 0.0 3.8e-30 104.2 0.0 1.6 1 0 0 1 1 1 1 Tudor domain SMN PF06003.7 EIE80509.1 - 0.0049 16.0 0.0 0.0099 15.0 0.0 1.4 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) Dak1_2 PF13684.1 EIE80509.1 - 0.026 13.4 0.4 0.26 10.1 0.0 2.2 2 0 0 2 2 2 0 Dihydroxyacetone kinase family RVT_1 PF00078.22 EIE80511.1 - 1.1e-08 34.6 0.0 1.7e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EIE80512.1 - 8.7e-18 64.5 0.0 3.7e-17 62.5 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 EIE80512.1 - 4e-14 52.4 0.9 1e-13 51.1 0.6 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE80512.1 - 1.4e-06 27.8 1.3 5.6e-06 25.9 0.7 2.2 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.1 EIE80512.1 - 4.8e-05 23.7 0.1 0.00046 20.6 0.0 2.4 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.15 EIE80512.1 - 0.00057 19.7 0.1 0.0021 17.9 0.0 2.0 1 0 0 1 1 1 1 Retroviral aspartyl protease Tudor-knot PF11717.3 EIE80512.1 - 0.019 14.6 0.7 0.054 13.2 0.5 1.8 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain YcgR_2 PF12945.2 EIE80512.1 - 0.028 14.2 0.0 0.42 10.5 0.0 2.5 2 0 0 2 2 2 0 Flagellar protein YcgR gag-asp_proteas PF13975.1 EIE80512.1 - 0.07 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Exo_endo_phos_2 PF14529.1 EIE80513.1 - 4.3e-12 45.6 0.0 7.2e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EIE80513.1 - 2.5e-08 34.1 0.1 3.2e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family CENP-F_leu_zip PF10473.4 EIE80514.1 - 0.0073 16.1 0.2 0.011 15.5 0.2 1.1 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2968 PF11180.3 EIE80514.1 - 0.0079 15.5 0.2 0.013 14.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2968) Rab5-bind PF09311.6 EIE80514.1 - 0.017 15.0 0.1 0.024 14.5 0.1 1.2 1 0 0 1 1 1 0 Rabaptin-like protein Spectrin PF00435.16 EIE80514.1 - 0.072 13.3 0.0 0.1 12.8 0.0 1.2 1 0 0 1 1 1 0 Spectrin repeat HALZ PF02183.13 EIE80514.1 - 0.19 11.4 1.0 0.31 10.7 0.7 1.3 1 0 0 1 1 1 0 Homeobox associated leucine zipper AlaDh_PNT_N PF05222.10 EIE80515.1 - 2.7e-28 98.6 0.0 3.8e-28 98.1 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 EIE80515.1 - 1.4e-16 60.5 0.0 2.3e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Rad1 PF02144.11 EIE80516.1 - 4.6e-21 74.7 0.1 6e-21 74.4 0.1 1.1 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 HMG_box PF00505.14 EIE80517.1 - 2e-13 50.4 0.1 2e-13 50.4 0.1 2.2 3 0 0 3 3 3 1 HMG (high mobility group) box SAM_1 PF00536.25 EIE80517.1 - 3.4e-13 49.5 0.3 8.3e-13 48.3 0.0 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) HMG_box_2 PF09011.5 EIE80517.1 - 5.5e-10 39.4 0.4 5.5e-10 39.4 0.3 2.5 2 1 1 3 3 3 1 HMG-box domain SAM_2 PF07647.12 EIE80517.1 - 3.9e-09 36.2 0.2 1.4e-08 34.4 0.0 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) NCD1 PF04904.8 EIE80517.1 - 0.00032 20.3 0.0 0.00072 19.2 0.0 1.5 1 0 0 1 1 1 1 NAB conserved region 1 (NCD1) RhoGAP PF00620.22 EIE80518.1 - 2.1e-14 53.3 1.7 6.7e-14 51.7 0.3 2.5 3 0 0 3 3 3 1 RhoGAP domain FCH PF00611.18 EIE80518.1 - 0.00059 19.9 0.7 0.048 13.8 0.0 3.0 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain HLH PF00010.21 EIE80519.1 - 4.2e-14 51.9 2.7 1e-13 50.7 1.9 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SLX9 PF15341.1 EIE80519.1 - 0.018 15.4 2.2 0.034 14.5 1.6 1.5 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 UpxZ PF06603.6 EIE80519.1 - 0.079 12.9 0.1 1.4 8.9 0.0 2.5 2 1 0 2 2 2 0 UpxZ family of transcription anti-terminator antagonists DUF3347 PF11827.3 EIE80519.1 - 0.9 9.5 4.7 1.4 8.9 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) zf-C2H2 PF00096.21 EIE80520.1 - 5e-13 48.5 6.4 3.4e-06 27.0 0.5 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIE80520.1 - 2.2e-10 40.1 9.1 2.8e-05 24.1 0.6 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EIE80520.1 - 1.1e-07 31.8 17.4 1.5e-06 28.2 2.1 3.8 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EIE80520.1 - 0.0076 16.3 1.9 0.41 10.8 0.1 2.8 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EIE80520.1 - 0.022 14.6 2.4 0.15 11.9 0.3 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-LYAR PF08790.6 EIE80520.1 - 0.16 11.6 5.1 0.75 9.5 0.2 3.1 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf-TRAF PF02176.13 EIE80520.1 - 0.29 11.5 5.7 0.75 10.2 0.7 2.3 1 1 1 2 2 2 0 TRAF-type zinc finger zf-met PF12874.2 EIE80520.1 - 0.65 10.2 5.2 2.4 8.4 0.2 2.8 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Abi PF02517.11 EIE80521.1 - 4.3 7.5 6.9 4.1 7.5 0.6 2.3 2 1 0 2 2 2 0 CAAX protease self-immunity DUF751 PF05421.6 EIE80521.1 - 6.2 7.1 11.0 0.43 10.8 0.6 2.7 2 2 0 2 2 2 0 Protein of unknown function (DUF751) Peptidase_M24 PF00557.19 EIE80522.1 - 2.2e-28 99.2 0.1 2.8e-28 98.9 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 DnaJ PF00226.26 EIE80523.1 - 5.1e-08 32.5 0.1 8.6e-08 31.8 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 EIE80523.1 - 0.008 15.9 0.1 0.0082 15.9 0.1 1.2 1 1 0 1 1 1 1 Pam16 Proteasome PF00227.21 EIE80524.1 - 2.4e-42 144.3 0.0 3e-42 144.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit DUF1669 PF07894.7 EIE80524.1 - 0.012 14.8 0.1 0.018 14.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1669) CLU PF13236.1 EIE80525.1 - 4.2e-86 287.9 0.2 2.3e-85 285.5 0.0 2.3 3 0 0 3 3 3 1 Clustered mitochondria eIF3_p135 PF12807.2 EIE80525.1 - 3.2e-46 157.3 0.7 1.1e-45 155.6 0.0 2.3 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.1 EIE80525.1 - 5.6e-29 99.8 16.6 8.9e-11 41.5 1.1 3.6 1 1 3 4 4 4 4 Tetratricopeptide repeat CLU_N PF15044.1 EIE80525.1 - 2.3e-23 82.1 0.2 7e-23 80.5 0.1 1.9 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_10 PF13374.1 EIE80525.1 - 4e-17 61.5 3.5 2.4e-06 27.2 0.0 4.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 EIE80525.1 - 6.7e-06 25.6 2.4 0.13 11.9 0.1 3.5 1 1 1 3 3 3 3 TPR repeat DUF727 PF05303.7 EIE80525.1 - 0.0016 18.1 0.0 0.0048 16.6 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF727) TPR_1 PF00515.23 EIE80525.1 - 0.05 13.2 2.1 17 5.1 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 EIE80525.1 - 0.1 12.5 11.2 17 5.6 0.0 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.1 EIE80525.1 - 0.39 10.6 5.2 78 3.4 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat DDE_3 PF13358.1 EIE80526.1 - 0.00013 21.7 0.0 0.00015 21.5 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease Sec7_N PF12783.2 EIE80528.1 - 9.3e-05 21.9 1.5 0.0087 15.4 0.0 3.4 3 1 1 4 4 4 2 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EIE80528.1 - 0.018 14.5 0.3 1.1 8.8 0.0 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1981) PIF1 PF05970.9 EIE80529.1 - 6.8e-11 41.7 0.1 2e-08 33.5 0.0 2.2 1 1 1 2 2 2 2 PIF1-like helicase Herpes_Helicase PF02689.9 EIE80529.1 - 0.00033 18.5 0.0 0.00053 17.8 0.0 1.2 1 0 0 1 1 1 1 Helicase AAA_30 PF13604.1 EIE80529.1 - 0.0019 17.8 0.0 0.0039 16.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 EIE80529.1 - 0.02 14.4 0.1 0.042 13.3 0.0 1.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.1 EIE80529.1 - 0.1 12.7 0.1 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Clat_adaptor_s PF01217.15 EIE80530.1 - 4.4e-06 26.4 0.3 6.7e-06 25.8 0.2 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF4337 PF14235.1 EIE80530.1 - 0.31 10.8 4.1 0.45 10.3 2.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF106 PF01956.11 EIE80530.1 - 5.9 6.3 7.5 9.2 5.7 5.2 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF106 Sec3_C PF09763.4 EIE80531.1 - 7.3e-149 497.0 33.8 9.6e-149 496.6 23.4 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.1 EIE80531.1 - 1.6e-11 43.9 0.2 5.3e-11 42.2 0.1 1.9 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Sec3_C_2 PF15278.1 EIE80531.1 - 0.0071 16.4 1.8 0.22 11.6 0.2 3.6 2 1 0 2 2 2 1 Sec3 exocyst complex subunit zf-C2H2 PF00096.21 EIE80532.1 - 0.00052 20.1 6.4 0.0061 16.8 2.4 2.8 2 0 0 2 2 2 1 Zinc finger, C2H2 type Adeno_E3A PF05248.7 EIE80532.1 - 0.0056 16.7 0.3 0.0092 16.0 0.2 1.4 1 0 0 1 1 1 1 Adenovirus E3A zf-C2H2_4 PF13894.1 EIE80532.1 - 0.032 14.5 3.5 0.032 14.5 2.5 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger Desulfoferrod_N PF06397.7 EIE80532.1 - 0.15 11.5 0.3 0.15 11.5 0.2 1.6 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain NAD_binding_10 PF13460.1 EIE80535.1 - 8.8e-16 58.4 0.0 1.2e-15 58.0 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EIE80535.1 - 2.9e-13 49.6 0.0 8.7e-08 31.6 0.0 2.1 2 0 0 2 2 2 2 NmrA-like family TrkA_N PF02254.13 EIE80535.1 - 0.00012 22.0 0.0 0.00023 21.1 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain Epimerase PF01370.16 EIE80535.1 - 0.0004 19.9 0.0 0.00063 19.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_2 PF03446.10 EIE80535.1 - 0.0026 17.6 0.0 0.0042 16.9 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EIE80535.1 - 0.0052 17.1 0.0 0.018 15.4 0.0 2.0 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.1 EIE80535.1 - 0.0096 16.1 0.0 0.11 12.7 0.0 2.2 2 1 0 2 2 2 1 Putative NAD(P)-binding 3Beta_HSD PF01073.14 EIE80535.1 - 0.038 12.6 0.0 0.086 11.5 0.0 1.6 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EIE80535.1 - 0.067 13.1 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase Semialdhyde_dh PF01118.19 EIE80535.1 - 0.11 12.8 0.0 0.31 11.3 0.0 1.8 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain ApbA PF02558.11 EIE80535.1 - 0.13 11.7 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA PBP1_TM PF14812.1 EIE80536.1 - 0.11 12.8 0.0 0.12 12.7 0.0 1.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ank_2 PF12796.2 EIE80537.1 - 8.5e-24 83.7 0.5 1.2e-12 47.9 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EIE80537.1 - 3.7e-22 76.9 2.4 2.5e-08 33.3 0.1 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.1 EIE80537.1 - 2.3e-19 67.5 1.0 5.5e-06 26.1 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 EIE80537.1 - 1.9e-16 59.6 1.4 4.3e-09 36.3 0.0 3.6 2 1 3 5 5 5 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EIE80537.1 - 2.1e-16 59.9 0.5 4.2e-08 33.4 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) DAGK_prokar PF01219.14 EIE80538.1 - 0.11 12.1 2.0 0.27 10.8 0.1 2.0 1 1 1 2 2 2 0 Prokaryotic diacylglycerol kinase 7tm_3 PF00003.17 EIE80538.1 - 0.8 8.9 11.5 3.3 6.9 8.0 1.8 1 1 1 2 2 2 0 7 transmembrane sweet-taste receptor of 3 GCPR Aldedh PF00171.17 EIE80539.1 - 1e-161 538.4 0.4 1.1e-161 538.2 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pam16 PF03656.8 EIE80540.1 - 1.4e-10 41.0 1.1 1.6e-10 40.8 0.8 1.1 1 0 0 1 1 1 1 Pam16 DUF937 PF06078.6 EIE80540.1 - 0.066 13.4 0.8 0.25 11.5 0.0 1.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF937) Phage_HK97_TLTM PF06120.6 EIE80541.1 - 0.038 13.3 0.2 0.056 12.7 0.1 1.2 1 0 0 1 1 1 0 Tail length tape measure protein DUF2036 PF09724.4 EIE80544.1 - 1.2e-37 129.8 0.5 2.5e-37 128.7 0.4 1.4 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) DNA_pol_E_B PF04042.11 EIE80547.1 - 1.9e-33 115.4 1.6 3.4e-33 114.6 1.1 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Pol_alpha_B_N PF08418.5 EIE80547.1 - 3e-13 49.9 3.3 3.1e-08 33.4 0.0 2.2 1 1 0 2 2 2 2 DNA polymerase alpha subunit B N-terminal ApoC-I PF04691.7 EIE80547.1 - 0.13 11.9 0.1 0.29 10.8 0.1 1.6 1 0 0 1 1 1 0 Apolipoprotein C-I (ApoC-1) Ribosomal_L14 PF00238.14 EIE80549.1 - 5e-19 68.2 0.0 5.3e-19 68.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e DHFR_1 PF00186.14 EIE80550.1 - 3.3e-41 140.5 0.0 4.5e-41 140.1 0.0 1.3 1 0 0 1 1 1 1 Dihydrofolate reductase WD40 PF00400.27 EIE80551.1 - 1.6e-12 46.8 0.3 0.0065 16.3 0.0 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat Lactonase PF10282.4 EIE80551.1 - 6.2e-05 22.2 0.0 0.0001 21.4 0.0 1.3 1 1 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Cytochrom_D1 PF02239.11 EIE80551.1 - 0.1 10.8 0.0 0.19 9.9 0.0 1.4 1 1 0 1 1 1 0 Cytochrome D1 heme domain Homeobox_KN PF05920.6 EIE80552.1 - 4.7e-19 67.8 0.7 1.1e-18 66.6 0.5 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 EIE80552.1 - 5e-06 26.0 2.2 5.9e-06 25.8 0.2 2.1 2 1 0 2 2 2 1 Homeobox domain Arf PF00025.16 EIE80553.1 - 4e-65 218.3 0.0 4.4e-65 218.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EIE80553.1 - 2.6e-08 33.2 0.0 3.4e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EIE80553.1 - 7.4e-08 31.4 0.1 0.00015 20.5 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.18 EIE80553.1 - 1.8e-06 27.8 0.0 5.7e-06 26.2 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EIE80553.1 - 4.8e-06 27.0 0.0 6.6e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 EIE80553.1 - 1.3e-05 24.6 0.0 1.6e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EIE80553.1 - 2.6e-05 23.4 0.0 2.8e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 EIE80553.1 - 0.014 14.8 0.0 0.051 13.0 0.0 1.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.22 EIE80553.1 - 0.053 12.9 0.0 1.6 8.1 0.0 2.0 1 1 0 2 2 2 0 Elongation factor Tu GTP binding domain RXT2_N PF08595.6 EIE80555.1 - 2.8e-12 46.6 8.7 5.7e-11 42.4 0.1 3.4 2 2 1 3 3 3 2 RXT2-like, N-terminal FGGY_N PF00370.16 EIE80556.1 - 1.7e-59 201.0 0.2 1.9e-59 200.9 0.2 1.0 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 EIE80556.1 - 0.044 13.0 0.0 0.057 12.7 0.0 1.4 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family SBDS PF01172.13 EIE80557.1 - 8.3e-17 60.7 0.3 9.1e-17 60.6 0.2 1.0 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein DUF3385 PF11865.3 EIE80558.1 - 0.0063 16.4 0.0 0.019 14.9 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3385) HTH_Tnp_Tc3_2 PF01498.13 EIE80559.1 - 1.3e-07 31.5 2.4 3.3e-07 30.2 0.3 2.4 1 1 1 2 2 2 1 Transposase HTH_23 PF13384.1 EIE80559.1 - 0.0011 18.5 0.0 0.0026 17.3 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_4 PF13613.1 EIE80559.1 - 0.0029 17.1 0.0 0.0055 16.2 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease HTH_30 PF13556.1 EIE80559.1 - 0.026 14.1 0.0 0.06 12.9 0.0 1.6 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain DevR PF01905.11 EIE80559.1 - 0.096 11.5 0.2 0.12 11.2 0.1 1.2 1 0 0 1 1 1 0 CRISPR-associated negative auto-regulator DevR/Csa2 FliL PF03748.9 EIE80559.1 - 0.11 12.5 0.1 0.26 11.3 0.0 1.6 1 1 0 1 1 1 0 Flagellar basal body-associated protein FliL Chromo PF00385.19 EIE80560.1 - 6.8e-10 38.4 0.5 1.5e-09 37.3 0.3 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.21 EIE80560.1 - 7.4e-10 38.9 0.0 1.5e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Tudor-knot PF11717.3 EIE80560.1 - 0.0042 16.7 0.1 0.011 15.3 0.1 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain UCH PF00443.24 EIE80560.1 - 0.041 12.9 0.1 0.061 12.4 0.1 1.6 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Chromo PF00385.19 EIE80561.1 - 5e-12 45.2 0.2 9.6e-12 44.3 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DDE_3 PF13358.1 EIE80562.1 - 7.9e-19 67.8 0.0 1.5e-18 66.9 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE80562.1 - 1.1e-09 38.1 1.1 4e-09 36.4 0.8 2.0 1 0 0 1 1 1 1 Transposase HTH_Tnp_4 PF13613.1 EIE80562.1 - 0.00075 18.9 0.0 0.0014 18.0 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease HTH_23 PF13384.1 EIE80562.1 - 0.0043 16.6 0.0 0.013 15.1 0.0 1.8 1 0 0 1 1 1 1 Homeodomain-like domain FAM70 PF14967.1 EIE80562.1 - 0.036 13.2 0.1 0.055 12.6 0.0 1.2 1 0 0 1 1 1 0 FAM70 protein HTH_Tnp_Tc3_2 PF01498.13 EIE80563.1 - 2.7e-11 43.3 1.0 5.1e-11 42.4 0.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.1 EIE80563.1 - 3.8e-11 42.9 0.0 7.6e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 EIE80563.1 - 0.0045 17.1 0.2 0.01 15.9 0.0 1.7 2 0 0 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.1 EIE80563.1 - 0.016 14.8 0.1 0.042 13.5 0.1 1.7 1 0 0 1 1 1 0 Homeodomain-like domain HTH_30 PF13556.1 EIE80563.1 - 0.14 11.7 0.0 1.4 8.5 0.0 2.2 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain Retrotrans_gag PF03732.12 EIE80564.1 - 2.4e-05 24.3 0.0 5.2e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein rve PF00665.21 EIE80565.1 - 1.1e-18 67.4 0.0 2.5e-18 66.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE80565.1 - 2.1e-16 59.9 0.4 4.8e-16 58.7 0.1 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE80565.1 - 1.6e-13 50.0 1.8 4.4e-13 48.6 1.3 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.21 EIE80566.1 - 1.5e-18 67.0 0.0 2e-17 63.3 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 EIE80566.1 - 1.4e-16 60.5 0.0 2.7e-16 59.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 EIE80566.1 - 3.8e-06 27.3 0.0 1.8e-05 25.1 0.0 2.3 2 0 0 2 2 2 1 Aspartyl protease Retrotrans_gag PF03732.12 EIE80566.1 - 6.7e-06 26.0 1.0 1.7e-05 24.7 0.0 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein UBN2_2 PF14227.1 EIE80566.1 - 3.5e-05 23.3 1.2 0.00089 18.8 0.1 3.6 4 1 0 4 4 4 1 gag-polypeptide of LTR copia-type gag-asp_proteas PF13975.1 EIE80566.1 - 0.0002 21.1 0.0 0.00041 20.1 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease UBN2 PF14223.1 EIE80566.1 - 0.00068 19.4 1.2 0.22 11.3 0.1 2.9 3 0 0 3 3 3 2 gag-polypeptide of LTR copia-type zf-H2C2 PF09337.5 EIE80566.1 - 0.0073 15.6 0.1 0.024 14.0 0.0 2.0 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Asp_protease_2 PF13650.1 EIE80567.1 - 8.6e-08 32.5 0.0 2.1e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 EIE80567.1 - 3.6e-07 30.0 0.1 1.5e-06 28.0 0.0 2.1 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.22 EIE80567.1 - 2.7e-05 23.6 0.1 6.1e-05 22.4 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.1 EIE80567.1 - 0.0004 20.1 0.0 0.00095 18.9 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.12 EIE80567.1 - 0.00046 20.1 3.7 0.0012 18.8 0.0 3.5 4 0 0 4 4 3 1 Retrotransposon gag protein Asp_protease PF09668.5 EIE80567.1 - 0.0055 16.2 0.6 0.012 15.1 0.1 1.8 2 0 0 2 2 2 1 Aspartyl protease Peptidase_M3_N PF08439.5 EIE80567.1 - 0.051 13.6 1.9 0.11 12.5 0.2 2.5 2 0 0 2 2 2 0 Oligopeptidase F DUF3479 PF11965.3 EIE80567.1 - 0.062 13.0 0.9 0.11 12.2 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3479) RVP_2 PF08284.6 EIE80567.1 - 0.092 12.6 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease IncA PF04156.9 EIE80567.1 - 0.21 11.1 3.8 0.61 9.6 2.6 1.7 1 0 0 1 1 1 0 IncA protein V-SNARE PF05008.10 EIE80567.1 - 0.44 10.7 9.2 0.47 10.6 4.5 2.6 2 0 0 2 2 1 0 Vesicle transport v-SNARE protein N-terminus FlxA PF14282.1 EIE80567.1 - 1 9.3 7.7 0.82 9.6 2.6 2.8 2 1 0 2 2 2 0 FlxA-like protein DDE_3 PF13358.1 EIE80568.1 - 9.3e-13 48.1 0.5 1.1e-12 47.9 0.3 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE80568.1 - 0.071 13.2 0.3 0.12 12.4 0.1 1.5 2 0 0 2 2 2 0 Integrase core domain rve PF00665.21 EIE80570.1 - 3.3e-28 98.1 0.1 2.1e-27 95.6 0.0 2.3 3 0 0 3 3 3 1 Integrase core domain rve_3 PF13683.1 EIE80570.1 - 2.3e-05 23.8 0.0 8.9e-05 21.9 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.5 EIE80570.1 - 0.0031 16.8 0.1 0.013 14.8 0.0 2.1 2 0 0 2 2 2 1 His(2)-Cys(2) zinc finger RVT_1 PF00078.22 EIE80571.1 - 4.1e-13 49.1 0.4 7.9e-07 28.6 0.0 2.5 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Spuma_A9PTase PF03539.9 EIE80571.1 - 0.00069 19.5 0.3 0.0023 17.8 0.1 1.9 1 1 1 2 2 2 1 Spumavirus aspartic protease (A9) DUF1759 PF03564.10 EIE80572.1 - 0.002 17.9 0.2 0.0029 17.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) Retrotrans_gag PF03732.12 EIE80572.1 - 0.0022 18.0 0.4 0.0048 16.9 0.0 1.7 2 0 0 2 2 2 1 Retrotransposon gag protein DUF2947 PF11163.3 EIE80572.1 - 0.0085 15.6 0.4 0.015 14.8 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2947) USP7_ICP0_bdg PF12436.3 EIE80573.1 - 0.087 12.0 0.0 0.091 11.9 0.0 1.0 1 0 0 1 1 1 0 ICP0-binding domain of Ubiquitin-specific protease 7 rve PF00665.21 EIE80575.1 - 1.9e-22 79.6 0.0 4.5e-22 78.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE80575.1 - 2.9e-13 49.6 0.1 5.8e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.12 EIE80575.1 - 8.1e-09 35.4 0.1 2.3e-08 34.0 0.1 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein Chromo PF00385.19 EIE80575.1 - 4.2e-08 32.7 0.1 9.7e-08 31.5 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 EIE80575.1 - 0.00047 19.5 1.6 0.0015 17.9 1.1 2.0 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger UBN2 PF14223.1 EIE80575.1 - 0.13 12.0 0.0 0.36 10.6 0.0 1.8 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type HTH_Tnp_Tc3_2 PF01498.13 EIE80576.1 - 7.3e-10 38.7 0.9 1.6e-09 37.6 0.3 1.9 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.1 EIE80576.1 - 1.5e-05 24.4 0.1 0.00012 21.6 0.0 2.4 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.1 EIE80576.1 - 0.023 14.6 0.0 0.064 13.2 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_38 PF13936.1 EIE80576.1 - 0.031 13.8 0.4 0.064 12.8 0.3 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4 PF04545.11 EIE80576.1 - 0.078 12.3 0.1 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 Trp_repressor PF01371.14 EIE80576.1 - 0.11 12.4 0.3 0.18 11.7 0.2 1.3 1 0 0 1 1 1 0 Trp repressor protein DDE_3 PF13358.1 EIE80577.1 - 2.6e-18 66.1 0.1 6.4e-18 64.9 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE80577.1 - 4.5e-09 36.2 0.7 1.9e-08 34.2 0.6 2.0 2 1 0 2 2 2 1 Transposase HTH_Tnp_Tc3_2 PF01498.13 EIE80578.1 - 7.3e-10 38.7 0.9 1.6e-09 37.6 0.3 1.9 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.1 EIE80578.1 - 1.5e-05 24.4 0.1 0.00012 21.6 0.0 2.4 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.1 EIE80578.1 - 0.023 14.6 0.0 0.064 13.2 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_38 PF13936.1 EIE80578.1 - 0.031 13.8 0.4 0.064 12.8 0.3 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4 PF04545.11 EIE80578.1 - 0.078 12.3 0.1 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 Trp_repressor PF01371.14 EIE80578.1 - 0.11 12.4 0.3 0.18 11.7 0.2 1.3 1 0 0 1 1 1 0 Trp repressor protein PMT PF02366.13 EIE80579.1 - 5.2e-80 268.3 22.4 5.2e-80 268.3 15.5 2.5 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EIE80579.1 - 9.7e-34 116.5 2.2 1.4e-33 116.0 1.5 1.2 1 0 0 1 1 1 1 MIR domain G-alpha PF00503.15 EIE80580.1 - 4e-40 137.7 2.7 2.7e-38 131.6 1.9 2.0 1 1 0 1 1 1 1 G-protein alpha subunit DUF4602 PF15375.1 EIE80582.1 - 1.3 9.1 16.5 5.6 7.0 11.5 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4602) KH_1 PF00013.24 EIE80583.1 - 5.5e-06 25.9 0.6 1.3e-05 24.7 0.4 1.6 1 0 0 1 1 1 1 KH domain PRELI PF04707.9 EIE80584.1 - 1.4e-45 154.7 0.1 1.7e-45 154.4 0.1 1.0 1 0 0 1 1 1 1 PRELI-like family Bac_DnaA PF00308.13 EIE80584.1 - 0.015 14.9 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial dnaA protein DUF1688 PF07958.6 EIE80586.1 - 4.3e-120 401.0 0.0 5.2e-120 400.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) MMS19_N PF14500.1 EIE80587.1 - 5.9e-89 297.8 1.4 6.4e-88 294.4 0.0 3.2 3 1 0 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.3 EIE80587.1 - 1.4e-71 241.4 15.7 9.3e-70 235.4 4.2 3.7 2 1 1 4 4 4 2 RNAPII transcription regulator C-terminal HEAT_EZ PF13513.1 EIE80587.1 - 0.1 13.1 5.3 15 6.2 0.0 5.5 8 0 0 8 8 8 0 HEAT-like repeat Sugar_tr PF00083.19 EIE80588.1 - 9e-127 423.3 31.2 1e-126 423.1 21.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIE80588.1 - 3.2e-30 105.0 53.6 1.6e-26 92.8 14.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.11 EIE80588.1 - 3.8 7.0 20.0 0.2 11.1 1.1 3.2 2 1 1 3 3 3 0 Ion channel regulatory protein UNC-93 RhoGAP PF00620.22 EIE80589.1 - 2.4e-09 36.9 0.0 0.00092 18.8 0.0 2.3 1 1 1 2 2 2 2 RhoGAP domain eIF_4G1 PF12152.3 EIE80589.1 - 0.065 13.1 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4G1 Aldedh PF00171.17 EIE80592.1 - 1.3e-121 406.2 0.1 3.3e-121 404.8 0.0 1.6 1 1 0 1 1 1 1 Aldehyde dehydrogenase family XRN_N PF03159.13 EIE80592.1 - 3.8e-94 314.5 0.0 2e-93 312.1 0.0 2.1 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus Chs3p PF12271.3 EIE80593.1 - 5.4e-97 324.3 23.8 2e-79 266.6 12.0 2.0 1 1 1 2 2 2 2 Chitin synthase III catalytic subunit Oligomerisation PF02410.10 EIE80594.1 - 1.2e-23 83.0 0.0 1.9e-23 82.3 0.0 1.3 1 0 0 1 1 1 1 Oligomerisation domain DUF2616 PF11077.3 EIE80596.1 - 0.02 14.3 0.3 0.03 13.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2616) RasGEF PF00617.14 EIE80597.1 - 1.4e-16 60.7 0.5 2.7e-16 59.8 0.4 1.5 1 0 0 1 1 1 1 RasGEF domain TAFH PF07531.9 EIE80597.1 - 0.09 12.4 3.1 1.6 8.3 0.3 2.9 2 1 0 2 2 2 0 NHR1 homology to TAF HTH_Tnp_Tc3_2 PF01498.13 EIE80598.1 - 1.6e-16 60.0 1.1 3.5e-16 58.9 0.8 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.1 EIE80598.1 - 2.9e-16 59.5 0.0 5e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 EIE80598.1 - 2.3e-08 34.1 0.4 3.6e-07 30.3 0.0 2.7 3 0 0 3 3 3 1 Winged helix-turn helix HTH_23 PF13384.1 EIE80598.1 - 0.00016 21.2 0.1 0.00061 19.3 0.0 2.0 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.1 EIE80598.1 - 0.0018 18.2 0.0 0.0062 16.5 0.0 2.0 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_17 PF12728.2 EIE80598.1 - 0.0074 16.5 0.6 0.29 11.3 0.0 3.0 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_24 PF13412.1 EIE80598.1 - 0.011 15.1 0.0 0.14 11.5 0.0 2.5 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding HTH_38 PF13936.1 EIE80598.1 - 0.012 15.1 0.0 0.036 13.6 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_7 PF02796.10 EIE80598.1 - 0.046 13.5 0.4 1 9.2 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase SpoIIID PF12116.3 EIE80598.1 - 0.046 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Stage III sporulation protein D HTH_IclR PF09339.5 EIE80598.1 - 0.049 13.2 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain MerR PF00376.18 EIE80598.1 - 0.07 12.6 0.3 7.2 6.2 0.0 3.0 3 0 0 3 3 3 0 MerR family regulatory protein RabGAP-TBC PF00566.13 EIE80600.1 - 1.5e-39 135.6 9.5 4.3e-32 111.3 0.2 3.3 3 0 0 3 3 3 3 Rab-GTPase-TBC domain EI24 PF07264.6 EIE80601.1 - 0.0011 18.4 10.5 0.0065 15.9 7.3 2.1 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF3671 PF12420.3 EIE80601.1 - 0.41 10.6 0.0 0.41 10.6 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function DUF4598 PF15370.1 EIE80602.1 - 2.4e-20 72.8 6.9 4.2e-20 72.0 4.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4598) Baculo_LEF5 PF04838.7 EIE80602.1 - 0.02 14.6 0.5 0.032 13.9 0.2 1.3 1 1 0 1 1 1 0 Baculoviridae late expression factor 5 Transglut_N PF00868.15 EIE80602.1 - 0.083 12.9 0.2 0.13 12.2 0.1 1.4 1 1 0 1 1 1 0 Transglutaminase family DUF2890 PF11081.3 EIE80602.1 - 0.42 10.6 8.8 0.57 10.2 6.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) CENP-B_dimeris PF09026.5 EIE80602.1 - 7.9 6.7 9.8 0.36 11.0 2.6 2.0 2 1 1 3 3 3 0 Centromere protein B dimerisation domain Med25_VWA PF11265.3 EIE80603.1 - 2.3e-10 39.8 0.6 6.9e-09 35.0 0.0 3.1 3 1 1 4 4 4 2 Mediator complex subunit 25 von Willebrand factor type A Peptidase_M24 PF00557.19 EIE80604.1 - 2.7e-53 180.6 0.0 3.7e-53 180.1 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EIE80604.1 - 2e-20 72.5 0.0 6.1e-19 67.7 0.0 2.2 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain SAPS PF04499.10 EIE80605.1 - 2e-81 274.0 0.9 1.6e-50 172.1 0.1 3.0 2 1 1 3 3 3 2 SIT4 phosphatase-associated protein bZIP_1 PF00170.16 EIE80606.1 - 4.3e-11 42.5 10.7 4.3e-11 42.5 7.4 1.7 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EIE80606.1 - 5.6e-07 29.2 12.2 5.6e-07 29.2 8.4 1.8 2 0 0 2 2 2 1 Basic region leucine zipper Aft1_OSA PF11785.3 EIE80606.1 - 0.00011 22.6 0.5 0.00011 22.6 0.4 2.5 3 0 0 3 3 3 1 Aft1 osmotic stress response (OSM) domain bZIP_Maf PF03131.12 EIE80606.1 - 0.0059 16.8 6.1 0.0059 16.8 4.2 1.7 1 1 1 2 2 2 1 bZIP Maf transcription factor DUF3680 PF12441.3 EIE80606.1 - 0.013 15.3 0.2 0.031 14.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3680) DUF2461 PF09365.5 EIE80606.1 - 0.043 13.2 1.5 0.082 12.2 0.8 1.6 1 1 1 2 2 2 0 Conserved hypothetical protein (DUF2461) HALZ PF02183.13 EIE80606.1 - 0.062 13.0 3.2 0.13 12.0 2.2 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF342 PF03961.8 EIE80606.1 - 0.8 8.0 4.2 0.94 7.8 2.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) IncA PF04156.9 EIE80606.1 - 3 7.4 8.9 3.7 7.0 6.2 1.2 1 0 0 1 1 1 0 IncA protein DivIC PF04977.10 EIE80606.1 - 7.9 6.0 9.9 1.3 8.6 3.2 2.0 2 0 0 2 2 2 0 Septum formation initiator BCDHK_Adom3 PF10436.4 EIE80607.1 - 3.5e-07 29.8 0.5 2.2e-06 27.2 0.3 2.1 1 1 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase Sds3 PF08598.6 EIE80608.1 - 1.3e-09 37.9 19.5 2.4e-09 37.0 13.5 1.4 1 0 0 1 1 1 1 Sds3-like SPX PF03105.14 EIE80608.1 - 0.4 10.4 13.2 0.67 9.6 8.9 1.6 1 1 0 1 1 1 0 SPX domain DUF3573 PF12097.3 EIE80608.1 - 0.85 8.1 2.6 1.4 7.4 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) WWE PF02825.15 EIE80609.1 - 0.0085 15.4 0.1 0.011 15.1 0.0 1.1 1 0 0 1 1 1 1 WWE domain IL1_propep PF02394.11 EIE80610.1 - 0.12 12.8 0.7 0.17 12.3 0.4 1.5 1 1 0 1 1 1 0 Interleukin-1 propeptide DUF3658 PF12395.3 EIE80610.1 - 0.13 11.7 0.8 0.2 11.2 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function Nucleoplasmin PF03066.10 EIE80613.1 - 0.0063 16.0 3.5 0.0076 15.7 2.4 1.3 1 0 0 1 1 1 1 Nucleoplasmin CENP-B_dimeris PF09026.5 EIE80613.1 - 0.013 15.7 5.5 0.023 14.9 3.8 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Fimbrillin_C PF15495.1 EIE80613.1 - 0.056 13.5 0.1 0.11 12.6 0.1 1.4 1 0 0 1 1 1 0 Major fimbrial subunit protein type IV, Fimbrillin, C-terminal CRPV_capsid PF08762.5 EIE80613.1 - 0.067 12.6 0.1 0.088 12.2 0.0 1.2 1 0 0 1 1 1 0 CRPV capsid protein like NOA36 PF06524.7 EIE80613.1 - 1.7 7.8 4.4 2.1 7.5 3.0 1.2 1 0 0 1 1 1 0 NOA36 protein Lectin_leg-like PF03388.8 EIE80614.1 - 7.8e-56 188.7 0.0 9.8e-56 188.4 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family 4HBT_3 PF13622.1 EIE80615.1 - 3e-35 122.1 0.0 3.9e-35 121.8 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 EIE80615.1 - 5e-31 107.0 0.0 1.5e-22 79.5 0.0 3.2 2 1 0 2 2 2 2 Acyl-CoA thioesterase DUF1044 PF06296.7 EIE80615.1 - 0.024 14.4 0.1 0.077 12.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1044) FAD-oxidase_C PF02913.14 EIE80616.1 - 2.9e-64 216.7 0.0 4.6e-64 216.0 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EIE80616.1 - 2.2e-36 124.3 0.0 3.9e-36 123.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain DUF1618 PF07762.9 EIE80616.1 - 0.047 13.8 0.0 0.093 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1618) 14-3-3 PF00244.15 EIE80617.1 - 2e-111 370.7 5.2 2.4e-111 370.5 3.6 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_12 PF13424.1 EIE80617.1 - 0.033 14.1 0.1 14 5.6 0.0 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat KIX PF02172.11 EIE80617.1 - 0.39 10.7 0.1 0.39 10.7 0.1 2.5 3 0 0 3 3 3 0 KIX domain DUF837 PF05769.6 EIE80617.1 - 0.44 10.0 5.5 1.4 8.4 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF837) BTB PF00651.26 EIE80618.1 - 2.5e-07 30.6 0.4 0.0027 17.6 0.0 2.7 1 1 0 2 2 2 2 BTB/POZ domain Glycos_transf_1 PF00534.15 EIE80619.1 - 3.4e-34 117.7 0.0 7e-34 116.7 0.0 1.5 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EIE80619.1 - 1.5e-14 54.2 0.0 2.5e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EIE80619.1 - 1.4e-10 41.2 0.0 2e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 EIE80619.1 - 4.2e-10 39.9 0.0 9.5e-10 38.8 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 EIE80619.1 - 0.00014 22.0 0.0 0.00029 21.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.1 EIE80619.1 - 0.029 14.2 0.0 0.081 12.7 0.0 1.7 2 0 0 2 2 2 0 Glycosyl transferase 4-like CAF1 PF04857.15 EIE80619.1 - 0.084 12.1 0.0 0.089 12.1 0.0 1.2 1 0 0 1 1 1 0 CAF1 family ribonuclease DDE_3 PF13358.1 EIE80620.1 - 5.9e-31 107.1 0.0 1.1e-30 106.2 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_1 PF01527.15 EIE80620.1 - 4.5e-05 23.3 0.2 0.00011 22.1 0.1 1.6 1 0 0 1 1 1 1 Transposase DDE_Tnp_ISAZ013 PF07592.6 EIE80620.1 - 0.0013 17.5 0.1 1.2 7.8 0.0 2.3 2 0 0 2 2 2 2 Rhodopirellula transposase DDE domain HTH_32 PF13565.1 EIE80620.1 - 0.0021 18.7 0.1 0.026 15.3 0.0 2.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.1 EIE80620.1 - 0.0066 16.4 0.0 0.026 14.5 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_psq PF05225.11 EIE80620.1 - 0.011 15.2 0.2 0.066 12.7 0.1 2.1 2 0 0 2 2 2 0 helix-turn-helix, Psq domain BRO1 PF03097.13 EIE80620.1 - 0.09 11.5 0.3 0.13 11.0 0.2 1.2 1 0 0 1 1 1 0 BRO1-like domain CP12 PF02672.10 EIE80620.1 - 0.09 13.2 1.8 0.27 11.7 1.2 1.8 1 0 0 1 1 1 0 CP12 domain YdjO PF14169.1 EIE80620.1 - 0.1 12.0 0.1 0.26 10.7 0.1 1.6 1 0 0 1 1 1 0 Cold-inducible protein YdjO HTH_23 PF13384.1 EIE80620.1 - 0.12 12.0 0.0 0.41 10.3 0.0 1.9 1 0 0 1 1 1 0 Homeodomain-like domain Phage_lysis PF03245.8 EIE80620.1 - 0.31 11.0 2.2 1.1 9.2 0.5 2.1 2 0 0 2 2 2 0 Bacteriophage Rz lysis protein Cactin_mid PF10312.4 EIE80621.1 - 0.073 12.3 1.9 0.38 9.9 1.3 2.0 1 1 0 1 1 1 0 Conserved mid region of cactin DUF1397 PF07165.6 EIE80621.1 - 0.08 12.1 0.6 0.18 10.9 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1397) Chromo PF00385.19 EIE80622.1 - 1e-10 41.0 0.6 3.5e-10 39.3 0.4 2.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Phage_integrase PF00589.17 EIE80623.1 - 5.7e-07 29.3 0.0 9.3e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family DUF3071 PF11268.3 EIE80623.1 - 0.0046 16.7 0.0 0.0085 15.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3071) Phage_int_SAM_1 PF02899.12 EIE80623.1 - 0.048 13.8 0.1 0.19 11.8 0.0 2.1 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain rve PF00665.21 EIE80625.1 - 1.7e-24 86.1 0.0 5.6e-24 84.5 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE80625.1 - 6.8e-17 61.5 0.0 1.3e-16 60.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE80625.1 - 3.7e-10 39.3 0.6 1.1e-09 37.8 0.4 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 EIE80625.1 - 0.00038 19.7 0.1 0.001 18.4 0.1 1.8 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger UBN2_2 PF14227.1 EIE80625.1 - 0.017 14.6 1.1 0.33 10.5 0.0 2.8 3 0 0 3 3 3 0 gag-polypeptide of LTR copia-type rve_3 PF13683.1 EIE80625.1 - 0.026 14.0 0.0 0.086 12.3 0.0 2.0 1 0 0 1 1 1 0 Integrase core domain UBN2 PF14223.1 EIE80625.1 - 0.062 13.0 0.6 0.16 11.7 0.1 1.9 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type GCR1_C PF12550.3 EIE80627.1 - 2.9e-24 84.7 0.1 3.8e-24 84.3 0.1 1.2 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Phage_integrase PF00589.17 EIE80629.1 - 0.00047 19.8 0.0 0.0038 16.9 0.0 2.0 1 1 0 1 1 1 1 Phage integrase family DDE_3 PF13358.1 EIE80631.1 - 9e-21 74.1 0.0 1.8e-20 73.1 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE80631.1 - 2.3e-15 56.4 1.1 9.3e-15 54.4 0.1 2.4 3 0 0 3 3 2 1 Transposase HTH_38 PF13936.1 EIE80631.1 - 1.2e-05 24.7 0.1 3.3e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_29 PF13551.1 EIE80631.1 - 1.3e-05 25.3 0.1 4.4e-05 23.5 0.1 1.9 2 0 0 2 2 1 1 Winged helix-turn helix HTH_23 PF13384.1 EIE80631.1 - 7.6e-05 22.2 0.1 0.0028 17.2 0.0 2.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.1 EIE80631.1 - 0.0011 19.7 2.8 0.24 12.2 0.1 3.7 4 0 0 4 4 3 1 Homeodomain-like domain HTH_28 PF13518.1 EIE80631.1 - 0.0013 18.7 0.0 0.0056 16.6 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.7 EIE80631.1 - 0.0013 18.1 1.7 0.024 14.0 0.0 3.2 4 0 0 4 4 4 1 Sigma-70, region 4 HTH_21 PF13276.1 EIE80631.1 - 0.0015 18.5 0.1 0.14 12.2 0.0 2.8 3 0 0 3 3 3 1 HTH-like domain HTH_7 PF02796.10 EIE80631.1 - 0.0026 17.6 1.3 0.1 12.4 0.0 2.8 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase rve PF00665.21 EIE80631.1 - 0.0062 16.6 0.0 0.015 15.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain LacI PF00356.16 EIE80631.1 - 0.018 14.6 1.7 2.8 7.6 0.2 2.6 3 0 0 3 3 3 0 Bacterial regulatory proteins, lacI family HTH_Tnp_4 PF13613.1 EIE80631.1 - 0.022 14.2 0.1 0.057 12.9 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease CPSase_L_D3 PF02787.14 EIE80631.1 - 0.071 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain HTH_36 PF13730.1 EIE80631.1 - 0.084 13.0 0.4 4.1 7.6 0.0 2.9 3 0 0 3 3 2 0 Helix-turn-helix domain Sigma70_r4 PF04545.11 EIE80631.1 - 0.1 11.9 0.3 0.79 9.0 0.0 2.6 4 0 0 4 4 4 0 Sigma-70, region 4 HTH_Tnp_ISL3 PF13542.1 EIE80631.1 - 0.15 11.2 2.5 8.4 5.6 0.0 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 HTH_17 PF12728.2 EIE80631.1 - 0.2 11.9 2.4 15 5.9 0.1 3.2 3 0 0 3 3 3 0 Helix-turn-helix domain Cript PF10235.4 EIE80632.1 - 0.012 15.9 0.4 0.013 15.7 0.3 1.1 1 0 0 1 1 1 0 Microtubule-associated protein CRIPT rve PF00665.21 EIE80633.1 - 2.3e-19 69.6 0.0 5.3e-19 68.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE80633.1 - 2.8e-17 62.8 0.7 7e-17 61.4 0.2 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE80633.1 - 3.3e-14 52.3 1.1 7.6e-14 51.1 0.7 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain F_actin_bind PF08919.5 EIE80633.1 - 0.014 15.1 0.1 0.074 12.7 0.0 2.3 2 0 0 2 2 2 0 F-actin binding RNase_H PF00075.19 EIE80633.1 - 0.034 14.4 0.0 0.16 12.3 0.0 2.1 2 0 0 2 2 2 0 RNase H SDA1 PF05285.7 EIE80634.1 - 0.0043 16.3 4.1 0.0045 16.3 2.9 1.0 1 0 0 1 1 1 1 SDA1 BCAS3 PF12490.3 EIE80634.1 - 0.068 12.4 2.2 0.083 12.1 1.5 1.2 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 3 DUF1777 PF08648.7 EIE80634.1 - 0.13 11.9 1.1 0.16 11.6 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) RVT_1 PF00078.22 EIE80635.1 - 1.7e-12 47.1 0.1 2e-09 37.1 0.0 2.5 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease PF09668.5 EIE80635.1 - 4e-09 36.0 0.0 7e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 EIE80635.1 - 3.2e-05 24.3 0.0 7.2e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 EIE80635.1 - 4.4e-05 23.3 0.0 0.00019 21.2 0.0 2.1 1 0 0 1 1 1 1 Retroviral aspartyl protease Spuma_A9PTase PF03539.9 EIE80635.1 - 0.0055 16.6 1.2 0.017 15.0 0.1 2.4 2 1 1 3 3 3 1 Spumavirus aspartic protease (A9) RVP_2 PF08284.6 EIE80635.1 - 0.0091 15.9 0.1 0.037 13.9 0.0 2.0 2 1 1 3 3 3 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EIE80635.1 - 0.014 15.1 0.0 0.032 14.0 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease MCR_beta_N PF02783.10 EIE80635.1 - 0.067 12.6 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Methyl-coenzyme M reductase beta subunit, N-terminal domain DUF1759 PF03564.10 EIE80636.1 - 0.00093 19.0 0.4 0.0018 18.0 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) Retrotrans_gag PF03732.12 EIE80636.1 - 0.1 12.6 0.1 0.1 12.6 0.0 2.2 2 0 0 2 2 2 0 Retrotransposon gag protein Sigma70_r1_1 PF03979.9 EIE80636.1 - 0.47 10.4 2.3 0.34 10.8 0.2 1.8 2 0 0 2 2 2 0 Sigma-70 factor, region 1.1 Transposase_21 PF02992.9 EIE80637.1 - 2.1e-21 76.0 0.0 4.1e-21 75.1 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 DUF1258 PF06869.7 EIE80637.1 - 0.0051 15.9 0.0 0.011 14.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) YebO PF13974.1 EIE80638.1 - 0.094 12.5 0.1 0.14 11.9 0.1 1.2 1 0 0 1 1 1 0 YebO-like protein rve PF00665.21 EIE80639.1 - 1.6e-24 86.2 0.0 5.3e-24 84.6 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 EIE80639.1 - 3.5e-10 39.3 0.6 1e-09 37.9 0.4 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVT_1 PF00078.22 EIE80639.1 - 0.00012 21.5 0.1 0.44 9.8 0.0 2.5 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.5 EIE80639.1 - 0.00036 19.8 0.1 0.00099 18.4 0.1 1.8 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger UBN2_2 PF14227.1 EIE80639.1 - 0.012 15.1 0.5 0.32 10.5 0.0 2.8 3 0 0 3 3 3 0 gag-polypeptide of LTR copia-type rve_3 PF13683.1 EIE80639.1 - 0.024 14.1 0.0 0.083 12.4 0.0 2.0 1 0 0 1 1 1 0 Integrase core domain UBN2 PF14223.1 EIE80639.1 - 0.048 13.4 0.1 0.15 11.8 0.1 1.8 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type rve PF00665.21 EIE80640.1 - 1.7e-20 73.3 0.0 5.3e-20 71.7 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE80640.1 - 5.9e-16 58.4 0.2 5.9e-16 58.4 0.2 2.3 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE80640.1 - 3.9e-07 29.6 0.1 1.3e-06 27.9 0.1 2.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.12 EIE80641.1 - 0.00013 21.9 0.1 0.00038 20.4 0.1 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein UBN2 PF14223.1 EIE80641.1 - 0.014 15.1 1.7 0.41 10.4 0.0 2.6 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type IncA PF04156.9 EIE80641.1 - 0.055 13.0 1.7 0.14 11.7 1.2 1.7 1 0 0 1 1 1 0 IncA protein Dynactin_p22 PF07426.6 EIE80642.1 - 0.024 13.9 0.8 0.032 13.5 0.6 1.2 1 0 0 1 1 1 0 Dynactin subunit p22 RRF_GI PF12614.3 EIE80643.1 - 0.021 14.6 0.1 0.021 14.6 0.1 1.1 1 0 0 1 1 1 0 Ribosome recycling factor HTH_Tnp_Tc3_2 PF01498.13 EIE80645.1 - 9.1e-17 60.8 0.3 1.5e-16 60.2 0.2 1.4 1 0 0 1 1 1 1 Transposase HTH_33 PF13592.1 EIE80645.1 - 2.3e-06 27.0 0.0 5.4e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.1 EIE80645.1 - 4.7e-06 27.3 0.1 1.8e-05 25.4 0.0 1.9 2 0 0 2 2 2 1 Homeodomain-like domain HTH_21 PF13276.1 EIE80645.1 - 0.00019 21.3 0.0 0.0016 18.4 0.0 2.2 2 0 0 2 2 2 1 HTH-like domain HTH_29 PF13551.1 EIE80645.1 - 0.00032 20.8 0.3 0.001 19.1 0.0 2.0 2 1 0 2 2 2 1 Winged helix-turn helix DDE_3 PF13358.1 EIE80647.1 - 2.1e-17 63.2 0.0 3e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE80647.1 - 4.8e-06 26.5 0.3 4.4e-05 23.4 0.6 2.0 2 0 0 2 2 2 1 Transposase DUF2695 PF10905.3 EIE80647.1 - 0.059 13.1 1.4 0.98 9.1 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2695) rve PF00665.21 EIE80648.1 - 2.7e-20 72.6 0.0 8.4e-20 71.0 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE80648.1 - 4.2e-11 42.6 0.3 9e-11 41.5 0.2 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE80648.1 - 2.1e-10 40.1 0.4 5.6e-10 38.7 0.3 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Ribonuc_P_40 PF08584.6 EIE80649.1 - 3.8e-52 177.0 1.0 4.3e-52 176.8 0.7 1.0 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit DUF416 PF04222.7 EIE80649.1 - 0.028 13.5 0.0 0.047 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF416) BTG PF07742.7 EIE80650.1 - 5.5e-31 106.5 0.0 7e-31 106.2 0.0 1.1 1 0 0 1 1 1 1 BTG family Inhibitor_I78 PF11720.3 EIE80650.1 - 0.14 11.9 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 Peptidase inhibitor I78 family Avl9 PF09794.4 EIE80651.1 - 1.8e-45 155.0 0.0 2.1e-45 154.8 0.0 1.0 1 0 0 1 1 1 1 Transport protein Avl9 Afi1 PF07792.7 EIE80651.1 - 0.00063 19.7 0.0 0.0015 18.5 0.0 1.9 1 1 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF2347 PF09804.4 EIE80651.1 - 0.058 12.6 0.0 0.068 12.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) Malate_DH PF12434.3 EIE80651.1 - 0.1 12.3 0.1 0.29 10.8 0.0 1.8 2 0 0 2 2 2 0 Malate dehydrogenase enzyme Avl9 PF09794.4 EIE80652.1 - 2.1e-41 141.6 0.0 3.4e-41 141.0 0.0 1.3 1 0 0 1 1 1 1 Transport protein Avl9 SPA PF08616.5 EIE80652.1 - 7.3e-06 25.6 0.0 1.3e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis Tenui_NS3 PF05310.7 EIE80653.1 - 0.082 12.7 0.1 0.24 11.2 0.0 1.7 1 1 1 2 2 2 0 Tenuivirus movement protein Phage_integrase PF00589.17 EIE80655.1 - 0.013 15.2 1.7 0.017 14.7 1.2 1.2 1 0 0 1 1 1 0 Phage integrase family EMP24_GP25L PF01105.19 EIE80655.1 - 0.025 14.2 3.6 0.043 13.5 2.5 1.4 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD RdRP_2 PF00978.16 EIE80655.1 - 0.027 13.1 1.8 0.032 12.9 1.2 1.1 1 0 0 1 1 1 0 RNA dependent RNA polymerase HrcA_DNA-bdg PF03444.10 EIE80655.1 - 0.035 13.5 0.3 0.035 13.5 0.2 1.7 2 0 0 2 2 2 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding ACCA PF03255.9 EIE80655.1 - 0.097 12.2 1.8 0.13 11.7 1.1 1.5 1 1 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF2457 PF10446.4 EIE80655.1 - 0.12 11.0 3.0 0.14 10.9 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) P4Ha_N PF08336.6 EIE80655.1 - 0.12 12.1 4.0 0.19 11.5 2.4 1.6 1 1 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region TipAS PF07739.8 EIE80655.1 - 0.18 12.1 0.8 0.31 11.3 0.6 1.4 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain DUF342 PF03961.8 EIE80655.1 - 0.22 9.9 4.8 0.25 9.7 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) TBPIP PF07106.8 EIE80655.1 - 0.58 9.6 11.6 0.57 9.7 7.5 1.4 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Mito_carr PF00153.22 EIE80656.1 - 1.9e-70 232.6 3.7 8.9e-24 83.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L50 PF10501.4 EIE80657.1 - 0.088 12.7 0.2 0.18 11.8 0.2 1.5 1 0 0 1 1 1 0 Ribosomal subunit 39S Inhibitor_I10 PF12559.3 EIE80657.1 - 0.41 10.9 3.2 0.83 9.9 0.0 2.3 1 1 0 2 2 2 0 Serine endopeptidase inhibitors zf-RVT PF13966.1 EIE80658.1 - 4e-06 27.0 0.5 4e-06 27.0 0.4 1.8 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase Pkinase PF00069.20 EIE80659.1 - 0.21 10.6 5.4 0.19 10.8 0.1 3.1 3 2 0 3 3 3 0 Protein kinase domain Auxin_resp PF06507.8 EIE80661.1 - 0.081 12.7 0.0 0.1 12.4 0.0 1.1 1 0 0 1 1 1 0 Auxin response factor SNF2_N PF00176.18 EIE80662.1 - 3.4e-67 226.3 0.2 5.6e-67 225.6 0.2 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EIE80662.1 - 1.7e-05 24.7 0.0 1.7e-05 24.7 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EIE80662.1 - 5.8e-05 22.6 0.0 0.00015 21.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIE80662.1 - 0.046 13.5 0.0 1 9.2 0.0 2.7 1 1 0 1 1 1 0 Helicase conserved C-terminal domain AMP-binding PF00501.23 EIE80663.1 - 3.6e-84 282.5 0.0 6.8e-84 281.6 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EIE80663.1 - 0.049 14.5 0.0 0.13 13.1 0.0 1.8 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain DUF3349 PF11829.3 EIE80664.1 - 0.17 12.2 1.6 0.32 11.4 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3349) BLVR PF06375.6 EIE80664.1 - 0.87 9.3 7.6 18 5.1 2.6 3.2 3 0 0 3 3 3 0 Bovine leukaemia virus receptor (BLVR) V-ATPase_G PF03179.10 EIE80665.1 - 1.4e-27 96.0 14.8 1.6e-27 95.8 10.2 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit Nop25 PF09805.4 EIE80665.1 - 0.1 12.6 10.4 0.12 12.3 7.2 1.1 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) MFMR PF07777.6 EIE80665.1 - 0.39 10.6 1.6 0.49 10.3 1.1 1.2 1 0 0 1 1 1 0 G-box binding protein MFMR DUF4407 PF14362.1 EIE80665.1 - 0.45 9.4 7.2 0.53 9.1 5.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Vfa1 PF08432.5 EIE80665.1 - 2.7 7.9 8.3 3.2 7.7 5.7 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 ATP-synt_B PF00430.13 EIE80665.1 - 10 5.9 20.0 1.2 8.9 8.2 2.0 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) Ribosomal_L3 PF00297.17 EIE80666.1 - 3e-120 400.5 9.7 3.5e-120 400.3 6.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 FadA PF09403.5 EIE80666.1 - 1.7 8.7 6.6 1.2 9.1 2.2 2.2 1 1 1 2 2 2 0 Adhesion protein FadA DUF2435 PF10363.4 EIE80667.1 - 4.9e-25 87.2 0.1 1.4e-24 85.8 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2435) DUF3679 PF12438.3 EIE80668.1 - 7.5 5.9 5.6 7.9 5.9 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3679) DUF812 PF05667.6 EIE80669.1 - 0.036 12.5 10.0 0.01 14.4 3.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF812) COG5 PF10392.4 EIE80669.1 - 0.053 13.4 4.3 0.23 11.4 0.1 2.4 1 1 1 2 2 2 0 Golgi transport complex subunit 5 IncA PF04156.9 EIE80669.1 - 0.78 9.3 13.1 0.12 12.0 4.6 2.2 2 0 0 2 2 2 0 IncA protein Ribosomal_L15e PF00827.12 EIE80669.1 - 2 7.8 5.3 2.3 7.6 1.2 2.3 2 0 0 2 2 2 0 Ribosomal L15 THOC7 PF05615.8 EIE80669.1 - 3.9 7.7 15.1 6.4 7.0 6.5 3.3 2 2 1 3 3 3 0 Tho complex subunit 7 Atg14 PF10186.4 EIE80669.1 - 9.4 5.0 10.9 3.3 6.5 5.4 1.9 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Mit_ribos_Mrp51 PF11709.3 EIE80670.1 - 2.4e-16 59.8 6.8 1.5e-13 50.6 4.7 3.7 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit LMBR1 PF04791.11 EIE80671.1 - 0.13 10.7 7.1 0.14 10.6 4.4 1.3 1 1 0 1 1 1 0 LMBR1-like membrane protein zf-C2H2 PF00096.21 EIE80672.1 - 2.5e-12 46.3 15.5 3.7e-06 26.9 2.3 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIE80672.1 - 3.8e-10 39.3 12.0 8.3e-05 22.6 1.5 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EIE80672.1 - 2.2e-09 37.1 15.0 1.5e-07 31.3 1.9 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EIE80672.1 - 0.012 15.6 6.1 0.25 11.5 0.2 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Ogr_Delta PF04606.7 EIE80672.1 - 0.013 15.1 0.9 0.62 9.7 0.0 2.6 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger zf-met PF12874.2 EIE80672.1 - 0.032 14.4 6.1 2.1 8.6 0.9 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-BED PF02892.10 EIE80672.1 - 0.088 12.5 6.6 0.24 11.1 0.3 2.5 2 0 0 2 2 2 0 BED zinc finger zf-C2H2_2 PF12756.2 EIE80672.1 - 0.8 9.8 5.8 1.3 9.2 2.0 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 EIE80672.1 - 2.7 8.0 7.3 2 8.4 0.4 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger DDE_3 PF13358.1 EIE80673.1 - 1e-08 35.0 0.0 1.2e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease HLH PF00010.21 EIE80674.1 - 1.9e-12 46.6 0.9 1.9e-12 46.6 0.6 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Mito_carr PF00153.22 EIE80675.1 - 7.3e-08 32.0 0.1 8e-08 31.8 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial carrier protein WD40 PF00400.27 EIE80676.1 - 1.6e-28 97.4 17.3 1.6e-08 34.0 0.1 6.7 5 1 1 6 6 6 5 WD domain, G-beta repeat Peptidase_M20 PF01546.23 EIE80676.1 - 3.3e-27 95.2 0.0 6e-27 94.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EIE80676.1 - 1.3e-10 40.9 0.0 3.1e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Nup160 PF11715.3 EIE80676.1 - 2.2e-06 26.1 4.9 0.00028 19.1 0.0 3.5 3 1 0 4 4 4 2 Nucleoporin Nup120/160 SpoU_sub_bind PF08032.7 EIE80676.1 - 0.12 12.4 0.0 1.6e+02 2.5 0.0 4.2 4 0 0 4 4 4 0 RNA 2'-O ribose methyltransferase substrate binding Pkinase PF00069.20 EIE80677.1 - 2.2e-26 92.5 0.0 4.6e-26 91.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE80677.1 - 8.2e-17 61.1 0.0 1.5e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 EIE80677.1 - 0.0043 16.9 0.0 0.04 13.8 0.0 2.4 2 0 0 2 2 2 1 Ras-binding domain of Byr2 DivIC PF04977.10 EIE80677.1 - 5.5 6.5 9.8 1.3 8.6 0.1 2.5 2 0 0 2 2 2 0 Septum formation initiator GATA PF00320.22 EIE80678.1 - 3e-17 61.6 1.4 6.5e-17 60.5 1.0 1.6 1 0 0 1 1 1 1 GATA zinc finger DZR PF12773.2 EIE80678.1 - 0.015 15.1 0.7 0.2 11.5 0.6 2.6 2 1 1 3 3 3 0 Double zinc ribbon Cupin_8 PF13621.1 EIE80678.1 - 0.039 13.4 0.4 0.054 12.9 0.3 1.2 1 0 0 1 1 1 0 Cupin-like domain eIF-5_eIF-2B PF01873.12 EIE80678.1 - 0.066 12.8 0.3 0.11 12.1 0.2 1.4 1 0 0 1 1 1 0 Domain found in IF2B/IF5 zf-RING_3 PF14369.1 EIE80678.1 - 0.15 12.1 1.1 0.32 11.0 0.8 1.5 1 0 0 1 1 1 0 zinc-finger Carboxyl_trans PF01039.17 EIE80679.1 - 1.5e-188 627.1 0.0 1.8e-188 626.9 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain Peptidase_A22B PF04258.8 EIE80680.1 - 1.5e-36 126.4 4.0 1.9e-36 126.0 2.8 1.1 1 0 0 1 1 1 1 Signal peptide peptidase RRM_1 PF00076.17 EIE80681.1 - 0.00014 21.3 0.1 0.0019 17.8 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE80681.1 - 0.0011 18.7 0.1 0.0025 17.6 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE80681.1 - 0.019 14.9 0.1 0.048 13.6 0.0 1.7 1 1 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Phage_int_SAM_5 PF13102.1 EIE80681.1 - 0.03 14.3 5.3 0.023 14.6 2.2 1.8 2 0 0 2 2 2 0 Phage integrase SAM-like domain ABC2_membrane_3 PF12698.2 EIE80681.1 - 0.95 8.4 5.8 1.3 7.9 4.0 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Ribosomal_L39 PF00832.15 EIE80682.1 - 3.8e-17 61.4 11.8 4.8e-17 61.1 8.2 1.2 1 0 0 1 1 1 1 Ribosomal L39 protein Bac_export_2 PF01312.14 EIE80683.1 - 1.1 8.0 3.1 1.6 7.5 2.1 1.1 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family TRAPPC9-Trs120 PF08626.6 EIE80684.1 - 7e-179 596.6 6.3 8.7e-179 596.3 4.4 1.1 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TRAPPC-Trs85 PF12739.2 EIE80684.1 - 0.00021 20.0 0.0 0.00037 19.2 0.0 1.3 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TPR_12 PF13424.1 EIE80684.1 - 0.01 15.7 0.1 0.029 14.3 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.1 EIE80684.1 - 0.017 14.7 0.1 0.038 13.6 0.1 1.5 1 0 0 1 1 1 0 TPR repeat TPR_1 PF00515.23 EIE80684.1 - 0.14 11.8 0.1 0.34 10.5 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.1 EIE80684.1 - 0.14 12.8 0.0 0.32 11.7 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat RhoGEF PF00621.15 EIE80685.1 - 4.3e-31 108.1 1.2 8.6e-31 107.1 0.8 1.5 1 0 0 1 1 1 1 RhoGEF domain PH_10 PF15411.1 EIE80685.1 - 5.3e-25 87.8 2.2 1.4e-24 86.4 1.5 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PB1 PF00564.19 EIE80685.1 - 7.5e-15 54.3 0.2 6.1e-14 51.4 0.0 2.4 2 0 0 2 2 2 1 PB1 domain PH PF00169.24 EIE80685.1 - 0.00011 22.3 2.1 0.0009 19.4 0.3 2.6 2 0 0 2 2 2 1 PH domain C9orf72-like PF15019.1 EIE80686.1 - 0.096 11.9 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 C9orf72-like protein family PLDc_2 PF13091.1 EIE80687.1 - 3.2e-10 39.8 0.1 0.00031 20.4 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 EIE80687.1 - 0.16 11.8 2.7 1.1 9.2 0.1 2.7 3 0 0 3 3 3 0 Phospholipase D Active site motif Cullin PF00888.17 EIE80688.1 - 1e-194 648.4 16.7 1.4e-194 648.0 11.6 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EIE80688.1 - 4e-26 90.6 5.3 1.4e-25 88.9 3.7 2.0 1 0 0 1 1 1 1 Cullin protein neddylation domain AA_kinase PF00696.23 EIE80690.1 - 9.7e-39 133.3 0.8 1.4e-38 132.8 0.6 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 EIE80690.1 - 1.2e-14 53.7 0.1 3.4e-14 52.3 0.1 1.8 1 0 0 1 1 1 1 PUA domain WD40 PF00400.27 EIE80691.1 - 3.4e-23 80.6 6.9 4.6e-10 38.9 0.0 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat LisH PF08513.6 EIE80691.1 - 0.00042 19.9 0.5 0.00089 18.9 0.3 1.6 1 0 0 1 1 1 1 LisH ADH_zinc_N PF00107.21 EIE80692.1 - 6.6e-16 58.0 0.0 1.2e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIE80692.1 - 5.2e-07 29.4 0.0 1.2e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PerB PF06590.6 EIE80693.1 - 0.098 12.9 0.1 0.12 12.6 0.1 1.2 1 0 0 1 1 1 0 PerB protein Lon_C PF05362.8 EIE80694.1 - 1.6e-71 239.8 0.3 2.8e-71 239.0 0.2 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.24 EIE80694.1 - 1.5e-22 80.1 0.0 6.4e-22 78.1 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.1 EIE80694.1 - 2e-14 53.1 0.2 1.5e-13 50.2 0.0 2.4 2 1 0 2 2 2 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.9 EIE80694.1 - 5e-09 36.0 0.0 2.6e-08 33.6 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EIE80694.1 - 2.9e-07 30.6 0.0 1.1e-06 28.8 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EIE80694.1 - 8.7e-07 29.7 0.8 4.1e-06 27.6 0.0 2.5 3 1 0 3 3 1 1 AAA domain AAA_2 PF07724.9 EIE80694.1 - 4e-06 26.8 0.0 0.00018 21.4 0.0 2.9 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 EIE80694.1 - 8.5e-06 25.6 0.0 8.9e-05 22.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_PrkA PF08298.6 EIE80694.1 - 3.1e-05 22.8 0.0 5.6e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 PrkA AAA domain RuvB_N PF05496.7 EIE80694.1 - 5e-05 22.4 0.0 0.0003 19.9 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus RNA_helicase PF00910.17 EIE80694.1 - 0.00011 22.2 0.0 0.00097 19.2 0.0 2.4 2 0 0 2 2 2 1 RNA helicase AAA_18 PF13238.1 EIE80694.1 - 0.00013 22.2 0.3 0.00096 19.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.6 EIE80694.1 - 0.00016 21.3 0.0 0.00098 18.7 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 EIE80694.1 - 0.00032 21.1 1.1 0.0014 18.9 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.1 EIE80694.1 - 0.0006 19.9 0.0 0.0054 16.8 0.0 2.6 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EIE80694.1 - 0.00095 18.6 0.1 0.0032 16.9 0.0 1.9 2 0 0 2 2 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 EIE80694.1 - 0.0012 18.7 0.0 0.0025 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EIE80694.1 - 0.0013 17.8 0.0 0.0027 16.8 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin NTPase_1 PF03266.10 EIE80694.1 - 0.0021 17.8 0.0 0.0054 16.4 0.0 1.7 1 0 0 1 1 1 1 NTPase NB-ARC PF00931.17 EIE80694.1 - 0.0021 16.9 0.0 0.0048 15.7 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain NACHT PF05729.7 EIE80694.1 - 0.0022 17.6 0.0 0.016 14.8 0.0 2.2 2 0 0 2 2 2 1 NACHT domain DUF258 PF03193.11 EIE80694.1 - 0.0035 16.5 0.0 0.0071 15.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 EIE80694.1 - 0.0065 16.7 1.1 0.051 13.8 0.0 2.6 1 1 1 2 2 2 1 ABC transporter AAA_19 PF13245.1 EIE80694.1 - 0.0071 16.0 0.0 0.018 14.7 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain MobB PF03205.9 EIE80694.1 - 0.0074 15.9 0.0 0.016 14.8 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Birna_VP4 PF01768.11 EIE80694.1 - 0.0082 15.2 0.2 0.018 14.0 0.1 1.5 1 1 0 1 1 1 1 Birnavirus VP4 protein AAA_25 PF13481.1 EIE80694.1 - 0.0082 15.5 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 EIE80694.1 - 0.017 14.7 0.0 0.035 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EIE80694.1 - 0.018 14.9 0.0 0.042 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.5 EIE80694.1 - 0.023 13.9 0.0 0.052 12.7 0.0 1.6 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Baculo_PEP_C PF04513.7 EIE80694.1 - 0.033 14.0 0.4 0.2 11.4 0.1 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ClpB_D2-small PF10431.4 EIE80694.1 - 0.039 13.8 0.0 0.12 12.3 0.0 1.8 1 0 0 1 1 1 0 C-terminal, D2-small domain, of ClpB protein AAA_10 PF12846.2 EIE80694.1 - 0.04 13.3 0.1 0.11 11.8 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain ResIII PF04851.10 EIE80694.1 - 0.049 13.4 0.1 0.42 10.4 0.0 2.4 2 1 0 3 3 2 0 Type III restriction enzyme, res subunit MMR_HSR1 PF01926.18 EIE80694.1 - 0.051 13.5 0.0 0.22 11.4 0.0 2.2 2 0 0 2 2 1 0 50S ribosome-binding GTPase Mg_chelatase PF01078.16 EIE80694.1 - 0.06 12.5 0.0 0.17 11.0 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI SRP54 PF00448.17 EIE80694.1 - 0.11 11.9 0.0 0.28 10.5 0.0 1.7 2 0 0 2 2 1 0 SRP54-type protein, GTPase domain AAA_21 PF13304.1 EIE80694.1 - 0.12 12.3 2.7 0.36 10.7 0.0 2.8 3 0 0 3 3 2 0 AAA domain CbiA PF01656.18 EIE80694.1 - 0.13 11.6 0.4 1.2 8.5 0.0 2.5 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF1191 PF06697.7 EIE80695.1 - 0.0057 15.5 0.0 0.007 15.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) DUF1183 PF06682.7 EIE80695.1 - 0.0078 15.8 1.3 0.012 15.2 0.0 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF1183) TMEM154 PF15102.1 EIE80695.1 - 0.0079 15.9 4.1 0.034 13.8 2.9 1.9 1 1 0 1 1 1 1 TMEM154 protein family ESSS PF10183.4 EIE80695.1 - 0.027 14.8 0.2 0.069 13.5 0.0 1.7 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) UPF0233 PF06781.7 EIE80695.1 - 0.067 12.8 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0233) ASFV_J13L PF05568.6 EIE80695.1 - 0.12 11.9 0.0 0.12 11.9 0.0 2.2 2 0 0 2 2 2 0 African swine fever virus J13L protein Peroxin-3 PF04882.7 EIE80695.1 - 3.2 6.3 6.6 0.99 8.0 0.2 2.0 2 0 0 2 2 2 0 Peroxin-3 ACOX PF01756.14 EIE80696.1 - 7.1e-51 172.2 0.0 2.8e-50 170.3 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 EIE80696.1 - 3.6e-14 53.1 0.1 1.3e-13 51.3 0.0 2.0 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 EIE80696.1 - 5.2e-14 51.4 1.1 9.5e-14 50.6 0.3 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 EIE80696.1 - 7.5e-09 35.8 0.3 2.4e-08 34.2 0.2 1.8 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain UBA_4 PF14555.1 EIE80697.1 - 1.8e-13 49.7 0.1 1.1e-12 47.2 0.1 2.3 2 0 0 2 2 2 1 UBA-like domain UBX PF00789.15 EIE80697.1 - 1.5e-11 44.1 0.1 3.6e-11 42.9 0.1 1.6 1 0 0 1 1 1 1 UBX domain Gp-FAR-1 PF05823.7 EIE80697.1 - 0.041 13.8 0.8 0.069 13.1 0.6 1.3 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) CUE PF02845.11 EIE80697.1 - 0.079 12.4 0.1 0.22 11.0 0.0 1.8 1 0 0 1 1 1 0 CUE domain UIM PF02809.15 EIE80697.1 - 1.6 8.5 6.3 0.18 11.4 0.7 2.3 2 0 0 2 2 2 0 Ubiquitin interaction motif Bromo_TP PF07524.8 EIE80698.1 - 6.2e-10 38.6 0.1 1.1e-09 37.9 0.1 1.4 1 0 0 1 1 1 1 Bromodomain associated Activator_LAG-3 PF11498.3 EIE80698.1 - 0.17 10.6 28.6 0.25 10.0 19.8 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Aldolase_II PF00596.16 EIE80699.1 - 1.8e-44 151.5 0.0 2.2e-44 151.2 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain rve PF00665.21 EIE80705.1 - 8.7e-22 77.4 0.0 4.2e-21 75.2 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.1 EIE80705.1 - 0.0018 17.7 0.0 0.0058 16.1 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVP PF00077.15 EIE80706.1 - 0.03 14.2 0.0 0.057 13.3 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease HTH_Tnp_Tc3_2 PF01498.13 EIE80708.1 - 0.00023 21.1 0.7 0.00032 20.6 0.5 1.2 1 0 0 1 1 1 1 Transposase HTH_Tnp_Tc3_2 PF01498.13 EIE80710.1 - 1.1e-05 25.4 2.3 2.2e-05 24.4 0.7 2.1 1 1 0 2 2 2 1 Transposase RVT_1 PF00078.22 EIE80711.1 - 4.6e-11 42.4 0.0 7.9e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Spuma_A9PTase PF03539.9 EIE80711.1 - 0.0011 18.9 0.4 0.0043 16.9 0.0 2.1 1 1 1 2 2 2 1 Spumavirus aspartic protease (A9) Stap_Strp_toxin PF01123.15 EIE80711.1 - 0.17 12.3 2.2 0.32 11.5 0.9 1.9 1 1 0 1 1 1 0 Staphylococcal/Streptococcal toxin, OB-fold domain Asp_protease PF09668.5 EIE80712.1 - 6.8e-09 35.3 0.1 1.1e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 EIE80712.1 - 3.6e-07 30.5 0.0 8.4e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 EIE80712.1 - 0.00093 19.0 2.2 0.0018 18.1 0.0 2.5 2 0 0 2 2 2 1 Retroviral aspartyl protease RVP_2 PF08284.6 EIE80712.1 - 0.0018 18.1 0.0 0.0035 17.2 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EIE80712.1 - 0.0031 17.2 0.1 0.006 16.3 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease SRCR PF00530.13 EIE80713.1 - 0.076 13.3 1.1 0.12 12.7 0.7 1.4 1 1 0 1 1 1 0 Scavenger receptor cysteine-rich domain Leader_Erm PF08253.6 EIE80714.1 - 0.33 10.4 0.3 0.33 10.4 0.2 2.1 2 0 0 2 2 2 0 Erm Leader peptide Trp_repressor PF01371.14 EIE80715.1 - 0.037 13.9 0.1 0.12 12.3 0.0 1.9 2 0 0 2 2 2 0 Trp repressor protein DDE_3 PF13358.1 EIE80716.1 - 1.5e-19 70.1 0.6 2.4e-19 69.5 0.4 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE80716.1 - 7.2e-07 29.1 0.3 2.5e-06 27.4 0.1 2.1 2 1 0 2 2 2 1 Transposase rve PF00665.21 EIE80716.1 - 0.0015 18.6 0.0 0.0028 17.7 0.0 1.6 1 1 0 1 1 1 1 Integrase core domain HMG_box_2 PF09011.5 EIE80716.1 - 0.016 15.5 0.4 0.044 14.1 0.2 1.8 2 0 0 2 2 2 0 HMG-box domain HMG_box PF00505.14 EIE80716.1 - 0.038 14.2 0.6 0.24 11.6 0.5 2.3 2 0 0 2 2 2 0 HMG (high mobility group) box THP2 PF09432.5 EIE80716.1 - 0.049 13.5 0.8 0.67 9.8 0.0 2.6 3 0 0 3 3 3 0 Tho complex subunit THP2 HTH_21 PF13276.1 EIE80716.1 - 0.12 12.4 0.1 3.4 7.7 0.0 2.8 3 0 0 3 3 3 0 HTH-like domain Viral_DNA_bi PF02236.12 EIE80716.1 - 0.14 12.2 0.3 2.2 8.5 0.0 2.3 2 0 0 2 2 2 0 Viral DNA-binding protein, all alpha domain DDE_3 PF13358.1 EIE80718.1 - 0.0036 17.0 0.0 0.0036 17.0 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease Transposase_21 PF02992.9 EIE80719.1 - 1.1e-22 80.3 0.1 2.3e-22 79.2 0.1 1.5 1 0 0 1 1 1 1 Transposase family tnp2 SHR3_chaperone PF08229.6 EIE80719.1 - 0.016 14.1 0.2 0.04 12.8 0.1 1.6 1 0 0 1 1 1 0 ER membrane protein SH3 3HCDH_N PF02737.13 EIE80719.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Transposase_21 PF02992.9 EIE80722.1 - 7.7e-10 38.2 0.2 1.7e-09 37.1 0.0 1.6 2 0 0 2 2 2 1 Transposase family tnp2 3HCDH_N PF02737.13 EIE80722.1 - 0.0047 16.5 0.0 0.0092 15.6 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Rep_fac_C PF08542.6 EIE80722.1 - 0.068 13.1 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 Replication factor C C-terminal domain RasGAP PF00616.14 EIE80724.1 - 0.11 12.1 0.3 0.13 11.8 0.2 1.1 1 0 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase DDE_3 PF13358.1 EIE80726.1 - 2e-17 63.2 0.8 6.8e-17 61.5 0.6 1.8 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE80726.1 - 7.3e-15 54.7 1.3 4.9e-14 52.1 0.2 2.4 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 EIE80726.1 - 1.5e-08 34.7 0.0 4.9e-08 33.0 0.0 1.9 1 0 0 1 1 1 1 Winged helix-turn helix HTH_11 PF08279.7 EIE80726.1 - 1.1e-07 31.3 0.1 1.9e-05 24.2 0.0 2.6 2 0 0 2 2 2 1 HTH domain HTH_7 PF02796.10 EIE80726.1 - 1.1e-07 31.5 4.4 7e-06 25.8 0.2 3.4 2 1 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_23 PF13384.1 EIE80726.1 - 1.4e-07 30.9 0.2 9.5e-05 21.9 0.0 2.9 3 0 0 3 3 2 1 Homeodomain-like domain HTH_32 PF13565.1 EIE80726.1 - 9.6e-07 29.5 0.4 9.5e-05 23.1 0.0 3.7 3 1 1 4 4 4 1 Homeodomain-like domain HTH_36 PF13730.1 EIE80726.1 - 5.5e-06 26.4 2.2 0.00047 20.2 0.3 3.6 3 1 1 4 4 3 1 Helix-turn-helix domain HTH_24 PF13412.1 EIE80726.1 - 7.5e-05 22.0 0.2 0.0079 15.5 0.1 3.1 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_38 PF13936.1 EIE80726.1 - 7.7e-05 22.1 0.5 0.00075 18.9 0.0 2.6 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_21 PF13276.1 EIE80726.1 - 8.6e-05 22.4 0.0 0.0031 17.4 0.0 3.0 3 0 0 3 3 3 1 HTH-like domain HTH_33 PF13592.1 EIE80726.1 - 0.00017 21.0 0.1 0.00094 18.6 0.0 2.3 2 0 0 2 2 2 1 Winged helix-turn helix HTH_6 PF01418.12 EIE80726.1 - 0.00018 21.1 0.8 0.015 14.9 0.1 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain, rpiR family HTH_28 PF13518.1 EIE80726.1 - 0.00025 20.9 0.0 0.039 13.9 0.0 3.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.1 EIE80726.1 - 0.00029 19.9 0.1 0.12 11.5 0.0 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 LacI PF00356.16 EIE80726.1 - 0.00093 18.7 0.1 1 9.0 0.0 2.5 2 0 0 2 2 2 2 Bacterial regulatory proteins, lacI family TrmB PF01978.14 EIE80726.1 - 0.0014 18.3 0.2 0.019 14.6 0.0 2.6 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB rve PF00665.21 EIE80726.1 - 0.0018 18.3 0.0 0.0079 16.2 0.0 2.2 1 1 0 1 1 1 1 Integrase core domain HTH_IclR PF09339.5 EIE80726.1 - 0.0021 17.5 0.0 0.024 14.2 0.0 2.6 3 0 0 3 3 3 1 IclR helix-turn-helix domain HTH_AsnC-type PF13404.1 EIE80726.1 - 0.0046 16.4 0.0 0.015 14.8 0.0 1.9 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_3 PF01381.17 EIE80726.1 - 0.0057 16.4 0.4 0.095 12.5 0.1 2.3 2 0 0 2 2 2 1 Helix-turn-helix GntR PF00392.16 EIE80726.1 - 0.0075 15.6 0.0 0.95 8.9 0.0 2.6 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family HTH_40 PF14493.1 EIE80726.1 - 0.0076 16.4 0.0 0.017 15.2 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_17 PF12728.2 EIE80726.1 - 0.0079 16.4 0.3 4.8 7.5 0.0 4.0 4 0 0 4 4 3 0 Helix-turn-helix domain KorB PF08535.5 EIE80726.1 - 0.0088 16.1 0.1 0.027 14.6 0.0 1.8 1 0 0 1 1 1 1 KorB domain Fe_dep_repress PF01325.14 EIE80726.1 - 0.013 15.4 1.6 0.57 10.1 0.0 3.1 3 0 0 3 3 3 0 Iron dependent repressor, N-terminal DNA binding domain HMG_box_2 PF09011.5 EIE80726.1 - 0.021 15.2 0.3 0.075 13.4 0.2 2.0 1 0 0 1 1 1 0 HMG-box domain GerE PF00196.14 EIE80726.1 - 0.021 14.1 0.2 0.061 12.6 0.1 1.8 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family Trp_repressor PF01371.14 EIE80726.1 - 0.041 13.8 0.2 0.14 12.0 0.1 1.9 2 0 0 2 2 1 0 Trp repressor protein HTH_Mga PF08280.6 EIE80726.1 - 0.051 13.3 0.1 0.16 11.7 0.0 1.8 2 0 0 2 2 1 0 M protein trans-acting positive regulator (MGA) HTH domain Arg_repressor PF01316.16 EIE80726.1 - 0.057 12.9 0.1 0.2 11.2 0.0 1.9 2 0 0 2 2 1 0 Arginine repressor, DNA binding domain HTH_22 PF13309.1 EIE80726.1 - 0.067 12.9 0.1 0.46 10.2 0.1 2.3 2 0 0 2 2 2 0 HTH domain Phage_terminase PF10668.4 EIE80726.1 - 0.068 12.9 0.1 0.068 12.9 0.1 2.0 2 0 0 2 2 1 0 Phage terminase small subunit HTH_5 PF01022.15 EIE80726.1 - 0.075 12.7 0.0 0.9 9.2 0.0 2.3 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family HMG_box PF00505.14 EIE80726.1 - 0.086 13.1 1.1 0.6 10.4 0.5 2.6 2 0 0 2 2 2 0 HMG (high mobility group) box HTH_10 PF04967.7 EIE80726.1 - 0.089 12.3 0.0 1.5 8.4 0.0 2.4 2 0 0 2 2 2 0 HTH DNA binding domain Sigma70_r4_2 PF08281.7 EIE80726.1 - 0.2 11.1 0.6 2.8 7.4 0.1 2.6 3 0 0 3 3 2 0 Sigma-70, region 4 THP2 PF09432.5 EIE80726.1 - 0.91 9.3 4.1 1.2 9.0 0.0 2.9 5 0 0 5 5 2 0 Tho complex subunit THP2 Chromo PF00385.19 EIE80729.1 - 1.1e-14 53.8 2.2 2.4e-14 52.7 1.5 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF3782 PF12644.2 EIE80729.1 - 0.2 11.4 1.8 0.47 10.2 1.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3782) HTH_Tnp_Tc3_2 PF01498.13 EIE80730.1 - 6.2e-11 42.1 1.6 1.4e-10 41.0 0.6 2.0 2 0 0 2 2 2 1 Transposase HTH_Tnp_4 PF13613.1 EIE80730.1 - 0.00033 20.1 0.0 0.00067 19.1 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease HTH_23 PF13384.1 EIE80730.1 - 0.0022 17.6 0.0 0.0056 16.2 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain RRM_1 PF00076.17 EIE80732.1 - 1.2e-18 66.4 0.0 1.7e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE80732.1 - 1e-13 51.0 0.0 1.5e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE80732.1 - 9.5e-09 34.9 0.0 1.5e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Corona_nucleoca PF00937.13 EIE80732.1 - 0.18 10.7 4.8 0.25 10.2 3.3 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Prenylcys_lyase PF07156.9 EIE80733.1 - 3.4e-46 157.8 0.0 4.3e-46 157.4 0.0 1.0 1 0 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.1 EIE80733.1 - 5e-09 36.0 0.0 1.4e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EIE80733.1 - 4e-06 26.6 0.0 0.0029 17.3 0.0 2.6 2 0 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.19 EIE80733.1 - 8.6e-06 24.8 0.0 0.00013 20.9 0.0 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EIE80733.1 - 0.00031 20.6 0.0 0.034 14.0 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EIE80733.1 - 0.0012 18.0 0.0 0.13 11.3 0.0 2.4 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 EIE80733.1 - 0.0085 16.1 0.0 1.6 8.7 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EIE80733.1 - 0.015 13.9 0.8 0.02 13.5 0.1 1.6 2 0 0 2 2 2 0 Tryptophan halogenase VTC PF09359.5 EIE80734.1 - 1.4e-52 178.5 0.1 2.6e-52 177.5 0.1 1.5 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 EIE80734.1 - 1.7e-17 64.1 11.7 7.1e-08 32.5 2.1 3.8 2 1 1 3 3 3 2 SPX domain DUF202 PF02656.10 EIE80734.1 - 1e-09 38.4 2.4 1e-09 38.4 1.7 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) WD40 PF00400.27 EIE80735.1 - 8e-41 136.5 9.5 7.5e-10 38.3 0.1 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 EIE80735.1 - 7.7e-11 42.0 0.5 9.8e-05 22.1 0.1 3.9 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 EIE80735.1 - 0.00021 19.6 0.6 0.002 16.5 0.1 2.0 1 1 1 2 2 2 1 Cytochrome D1 heme domain Coatomer_WDAD PF04053.9 EIE80735.1 - 0.0024 16.7 0.1 0.024 13.4 0.1 2.3 1 1 2 3 3 3 2 Coatomer WD associated region PAZ PF02170.17 EIE80735.1 - 0.012 14.8 0.0 0.022 14.0 0.0 1.4 1 0 0 1 1 1 0 PAZ domain DUF3312 PF11768.3 EIE80735.1 - 0.098 10.8 0.0 0.97 7.5 0.0 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3312) Erg28 PF03694.8 EIE80736.1 - 1.9e-39 134.0 1.2 2.3e-39 133.8 0.8 1.1 1 0 0 1 1 1 1 Erg28 like protein EOS1 PF12326.3 EIE80736.1 - 0.075 12.6 0.6 0.25 10.9 0.0 1.8 1 1 1 2 2 2 0 N-glycosylation protein PAXIP1_C PF15364.1 EIE80737.1 - 0.028 14.3 2.6 0.047 13.5 1.8 1.3 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein LEA_5 PF00477.12 EIE80737.1 - 0.11 12.8 0.5 0.11 12.8 0.3 1.9 2 0 0 2 2 2 0 Small hydrophilic plant seed protein MIP-T3 PF10243.4 EIE80737.1 - 2.8 6.3 11.7 3.8 5.8 8.1 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 PDZ PF00595.19 EIE80738.1 - 0.11 12.6 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 PDZ domain (Also known as DHR or GLGF) RabGAP-TBC PF00566.13 EIE80740.1 - 1.2e-28 100.1 9.6 2.2e-28 99.1 6.7 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Arginosuc_synth PF00764.14 EIE80741.1 - 5.9e-148 493.0 0.0 6.9e-148 492.8 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.8 EIE80741.1 - 0.0014 17.9 0.0 0.0022 17.2 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.11 EIE80741.1 - 0.04 12.4 0.0 0.057 11.9 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase Asn_synthase PF00733.16 EIE80741.1 - 0.073 12.5 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase Tropomyosin PF00261.15 EIE80742.1 - 0.0021 17.2 3.4 0.0025 16.9 2.4 1.1 1 0 0 1 1 1 1 Tropomyosin DUF641 PF04859.7 EIE80742.1 - 0.0044 16.7 2.5 0.0059 16.3 1.7 1.2 1 0 0 1 1 1 1 Plant protein of unknown function (DUF641) Uso1_p115_C PF04871.8 EIE80742.1 - 0.0049 16.7 2.1 0.0064 16.4 1.4 1.1 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region DUF4515 PF14988.1 EIE80742.1 - 0.0073 15.9 7.1 0.0095 15.6 4.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4515) DUF3450 PF11932.3 EIE80742.1 - 0.012 14.8 5.4 0.014 14.7 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) FliJ PF02050.11 EIE80742.1 - 0.028 14.4 3.3 0.042 13.9 2.3 1.1 1 0 0 1 1 1 0 Flagellar FliJ protein DUF2564 PF10819.3 EIE80742.1 - 0.046 13.8 1.6 0.067 13.3 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2564) Sec20 PF03908.8 EIE80742.1 - 0.25 11.0 4.2 0.59 9.8 2.5 1.8 1 1 1 2 2 2 0 Sec20 Fib_alpha PF08702.5 EIE80742.1 - 0.81 9.8 8.0 1.1 9.3 5.6 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF600 PF04634.7 EIE80742.1 - 0.86 9.6 6.1 0.21 11.6 1.0 1.9 1 1 1 2 2 2 0 Protein of unknown function, DUF600 NPV_P10 PF05531.7 EIE80742.1 - 0.97 9.7 6.1 2.1 8.6 1.0 2.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein SlyX PF04102.7 EIE80742.1 - 1.4 9.3 7.0 0.86 10.0 2.2 2.2 1 1 1 2 2 2 0 SlyX DUF747 PF05346.6 EIE80743.1 - 7.4e-97 324.3 1.3 1.5e-96 323.3 0.9 1.5 1 1 0 1 1 1 1 Eukaryotic membrane protein family DUF2371 PF10177.4 EIE80743.1 - 0.25 11.1 1.0 0.94 9.3 0.0 2.3 3 0 0 3 3 3 0 Uncharacterised conserved protein (DUF2371) RasGEF PF00617.14 EIE80745.1 - 1.5e-32 112.8 0.0 2.6e-32 112.0 0.0 1.3 1 0 0 1 1 1 1 RasGEF domain DSPc PF00782.15 EIE80746.1 - 3e-08 33.3 0.0 3.8e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EIE80746.1 - 2.1e-06 27.2 0.0 2.2e-05 23.8 0.0 1.9 1 1 1 2 2 2 1 Protein-tyrosine phosphatase CDKN3 PF05706.7 EIE80746.1 - 0.021 14.2 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.1 EIE80746.1 - 0.056 13.4 0.0 0.067 13.2 0.0 1.1 1 0 0 1 1 1 0 Inositol hexakisphosphate Malic_M PF03949.10 EIE80747.1 - 8.1e-80 268.0 0.0 1.1e-79 267.6 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 EIE80747.1 - 2.6e-59 199.8 0.0 4.7e-59 199.0 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Bax1-I PF01027.15 EIE80748.1 - 1.7e-33 115.9 21.3 4.9e-31 107.9 9.3 2.0 1 1 1 2 2 2 2 Inhibitor of apoptosis-promoting Bax1 DUF1145 PF06611.7 EIE80748.1 - 0.077 12.6 1.7 0.23 11.1 1.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1145) HSP70 PF00012.15 EIE80749.1 - 4e-106 355.2 3.4 4e-106 355.2 2.3 1.5 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 EIE80749.1 - 4.2e-14 51.8 1.0 4.2e-14 51.8 0.7 1.6 2 0 0 2 2 2 1 MreB/Mbl protein PilM_2 PF11104.3 EIE80749.1 - 1.7e-05 23.8 0.4 5.4e-05 22.2 0.3 1.8 1 1 0 1 1 1 1 Type IV pilus assembly protein PilM; TFIIS_C PF01096.13 EIE80750.1 - 4.2e-19 67.8 6.0 7.5e-19 67.0 4.2 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Zn_Tnp_IS1595 PF12760.2 EIE80750.1 - 0.0058 16.4 4.3 0.015 15.0 3.0 1.7 1 1 0 1 1 1 1 Transposase zinc-ribbon domain Baculo_LEF5_C PF11792.3 EIE80750.1 - 0.0096 15.2 3.6 0.024 14.0 2.5 1.6 1 1 0 1 1 1 1 Baculoviridae late expression factor 5 C-terminal domain PH_10 PF15411.1 EIE80750.1 - 0.061 13.5 0.0 0.07 13.3 0.0 1.2 1 1 0 1 1 1 0 Pleckstrin homology domain PhnA_Zn_Ribbon PF08274.7 EIE80750.1 - 0.49 10.2 4.5 6.4 6.6 3.1 2.2 1 1 0 1 1 1 0 PhnA Zinc-Ribbon Kelch_3 PF13415.1 EIE80751.1 - 4e-20 71.4 0.0 1.9e-08 34.2 0.0 3.5 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_4 PF13418.1 EIE80751.1 - 5.7e-19 67.6 4.5 2.3e-08 33.6 0.0 3.3 2 1 1 3 3 3 2 Galactose oxidase, central domain Kelch_1 PF01344.20 EIE80751.1 - 1.4e-15 56.5 0.7 2.8e-06 26.7 0.1 3.2 3 0 0 3 3 3 3 Kelch motif Kelch_6 PF13964.1 EIE80751.1 - 8.8e-13 47.8 0.8 0.0012 18.9 0.0 3.4 2 1 1 3 3 3 3 Kelch motif Kelch_2 PF07646.10 EIE80751.1 - 5.5e-11 41.7 1.3 0.008 15.9 0.2 3.4 3 0 0 3 3 3 3 Kelch motif Kelch_5 PF13854.1 EIE80751.1 - 8.5e-08 31.9 1.2 0.021 14.7 0.0 3.3 3 0 0 3 3 3 2 Kelch motif Sas10_Utp3 PF04000.10 EIE80752.1 - 1.9e-18 66.4 1.5 4.8e-18 65.1 1.0 1.7 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Phi-29_GP16_7 PF06720.6 EIE80752.1 - 0.011 15.3 0.2 0.03 13.9 0.1 1.9 1 0 0 1 1 1 0 Bacteriophage phi-29 early protein GP16.7 tRNA-synt_2 PF00152.15 EIE80753.1 - 1.3e-82 277.3 0.7 1.3e-82 277.3 0.5 1.4 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EIE80753.1 - 0.00085 19.1 0.6 0.0018 18.0 0.4 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EIE80753.1 - 0.0045 16.2 1.8 1.2 8.3 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) zf-C2H2 PF00096.21 EIE80754.1 - 0.00076 19.6 1.9 0.0013 18.9 1.3 1.4 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIE80754.1 - 0.0038 17.4 1.9 0.0062 16.7 1.3 1.3 1 0 0 1 1 1 1 C2H2-type zinc finger zf-H2C2_5 PF13909.1 EIE80754.1 - 0.0082 16.3 2.4 0.014 15.6 1.6 1.4 1 0 0 1 1 1 1 C2H2-type zinc-finger domain DUF3505 PF12013.3 EIE80754.1 - 0.018 15.2 0.2 0.019 15.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3505) NAD_binding_6 PF08030.7 EIE80755.1 - 2.3e-17 63.3 0.1 6.6e-15 55.3 0.0 2.3 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EIE80755.1 - 2.1e-16 60.1 8.7 2.1e-16 60.1 6.0 2.1 2 1 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EIE80755.1 - 1.9e-07 30.8 0.0 1.7e-06 27.8 0.0 2.2 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 EIE80755.1 - 0.085 13.4 0.0 0.57 10.7 0.0 2.3 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain Nol1_Nop2_Fmu PF01189.12 EIE80756.1 - 3.3e-22 79.1 0.2 6.8e-21 74.8 0.1 2.1 1 1 0 1 1 1 1 NOL1/NOP2/sun family FtsJ PF01728.14 EIE80756.1 - 0.0071 16.3 0.0 0.0099 15.8 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase UPF0004 PF00919.15 EIE80756.1 - 0.04 13.7 0.7 0.18 11.6 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized protein family UPF0004 TPPII_N PF12583.3 EIE80756.1 - 0.14 12.2 5.6 0.42 10.7 0.5 2.9 2 1 0 2 2 2 0 Tripeptidyl peptidase II N terminal AMP-binding PF00501.23 EIE80757.1 - 4.8e-93 311.8 0.0 6e-93 311.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme NT5C PF06941.7 EIE80757.1 - 0.0028 17.1 0.0 0.0056 16.1 0.0 1.4 1 0 0 1 1 1 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) Methyltransf_11 PF08241.7 EIE80758.1 - 4.6e-08 33.4 0.0 1.2e-07 32.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIE80758.1 - 0.00013 21.5 0.0 0.00032 20.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIE80758.1 - 0.00018 21.2 0.0 0.00024 20.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIE80758.1 - 0.00085 18.4 0.0 0.0013 17.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EIE80758.1 - 0.0038 17.6 0.0 0.015 15.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_8 PF05148.10 EIE80758.1 - 0.0068 16.0 0.0 0.0098 15.5 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_25 PF13649.1 EIE80758.1 - 0.013 15.8 0.0 0.049 14.0 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Orthopox_A5L PF06193.6 EIE80758.1 - 0.015 15.1 0.0 0.026 14.4 0.0 1.3 1 0 0 1 1 1 0 Orthopoxvirus A5L protein-like Methyltransf_11 PF08241.7 EIE80759.1 - 4.2e-12 46.3 0.0 8.3e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIE80759.1 - 9e-12 45.0 0.0 1.2e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIE80759.1 - 5.6e-10 38.7 0.0 1.8e-09 37.0 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EIE80759.1 - 8.9e-10 38.3 0.0 1.8e-09 37.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIE80759.1 - 1.8e-08 34.7 0.1 6.6e-08 32.9 0.0 2.0 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIE80759.1 - 2.3e-06 27.9 0.0 1.1e-05 25.6 0.0 2.1 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EIE80759.1 - 4.3e-05 23.2 0.0 8.9e-05 22.2 0.0 1.4 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_18 PF12847.2 EIE80759.1 - 0.00012 22.6 0.0 0.00052 20.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 EIE80759.1 - 0.0003 20.0 0.0 0.00039 19.7 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_4 PF02390.12 EIE80759.1 - 0.00054 19.0 0.0 0.0035 16.4 0.0 2.0 2 0 0 2 2 2 1 Putative methyltransferase CMAS PF02353.15 EIE80759.1 - 0.0012 18.0 0.1 0.0018 17.4 0.0 1.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase MetW PF07021.7 EIE80759.1 - 0.009 15.3 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.9 EIE80759.1 - 0.011 15.1 0.1 0.024 13.9 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_26 PF13659.1 EIE80759.1 - 0.018 15.0 0.0 0.057 13.4 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain FmrO PF07091.6 EIE80759.1 - 0.024 13.6 0.0 0.034 13.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) PCMT PF01135.14 EIE80759.1 - 0.047 13.2 0.0 0.082 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.7 EIE80760.1 - 1.7e-07 31.6 0.0 2.6e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIE80760.1 - 7e-07 28.9 0.1 1.4e-06 27.9 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIE80760.1 - 2.8e-06 27.1 0.0 3.2e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIE80760.1 - 3e-06 27.6 0.2 9e-06 26.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_2 PF00891.13 EIE80760.1 - 4.4e-06 26.0 0.0 4.9e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_25 PF13649.1 EIE80760.1 - 6.2e-05 23.2 0.1 0.00012 22.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIE80760.1 - 0.00016 22.2 0.0 0.00023 21.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EIE80760.1 - 0.00026 20.0 0.0 0.00047 19.2 0.0 1.3 1 1 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 EIE80760.1 - 0.00099 18.5 0.0 0.0012 18.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.7 EIE80760.1 - 0.0022 17.3 0.0 0.0028 17.0 0.0 1.1 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW CMAS PF02353.15 EIE80760.1 - 0.003 16.6 0.0 0.0038 16.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase FmrO PF07091.6 EIE80760.1 - 0.0047 15.9 0.0 0.0048 15.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) Ubie_methyltran PF01209.13 EIE80760.1 - 0.0065 15.5 0.1 0.013 14.6 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EIE80760.1 - 0.025 14.6 0.0 0.04 13.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_9 PF08003.6 EIE80760.1 - 0.029 13.0 0.0 0.038 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) PCMT PF01135.14 EIE80760.1 - 0.046 13.2 0.0 0.063 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Enolase_C PF00113.17 EIE80761.1 - 2.1e-156 519.3 0.1 3.1e-156 518.8 0.1 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 EIE80761.1 - 1.6e-55 186.6 0.2 2.7e-55 185.8 0.1 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MAAL_C PF07476.6 EIE80761.1 - 0.0039 16.1 0.4 0.015 14.2 0.0 2.0 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus MR_MLE_C PF13378.1 EIE80761.1 - 0.012 15.5 0.1 0.039 13.9 0.0 1.9 2 0 0 2 2 2 0 Enolase C-terminal domain-like DNA_ligase_aden PF01653.13 EIE80761.1 - 0.093 11.6 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 NAD-dependent DNA ligase adenylation domain PUA PF01472.15 EIE80762.1 - 2.2e-20 72.1 0.2 3.4e-20 71.5 0.1 1.3 1 0 0 1 1 1 1 PUA domain GHBP PF12772.2 EIE80763.1 - 0.00013 21.5 3.7 0.00022 20.7 2.6 1.4 1 0 0 1 1 1 1 Growth hormone receptor binding DnaJ PF00226.26 EIE80764.1 - 5.5e-20 70.8 1.2 2e-19 69.0 0.8 2.1 1 0 0 1 1 1 1 DnaJ domain Wzy_C PF04932.10 EIE80765.1 - 0.0077 16.0 0.2 0.013 15.2 0.1 1.3 1 0 0 1 1 1 1 O-Antigen ligase BatA PF07584.6 EIE80765.1 - 0.023 14.8 0.5 0.063 13.4 0.3 1.7 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal DUF347 PF03988.7 EIE80765.1 - 0.1 12.5 0.5 0.19 11.6 0.4 1.4 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) OppC_N PF12911.2 EIE80765.1 - 0.13 11.6 1.2 0.33 10.3 0.8 1.7 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C DUF900 PF05990.7 EIE80766.1 - 1.1e-05 24.8 0.0 1.4e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Ser_hydrolase PF06821.8 EIE80766.1 - 0.0029 17.2 0.1 0.0042 16.7 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase Abhydrolase_5 PF12695.2 EIE80766.1 - 0.014 15.1 0.0 0.022 14.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF4102 PF13356.1 EIE80767.1 - 0.092 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4102) TMF_TATA_bd PF12325.3 EIE80769.1 - 3.7e-05 23.4 0.3 4.4e-05 23.2 0.2 1.1 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding Golgin_A5 PF09787.4 EIE80769.1 - 0.00038 19.1 3.0 0.00044 18.9 2.1 1.0 1 0 0 1 1 1 1 Golgin subfamily A member 5 DUF948 PF06103.6 EIE80769.1 - 0.00044 20.0 0.7 0.00056 19.7 0.5 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF948) CENP-F_leu_zip PF10473.4 EIE80769.1 - 0.0038 17.0 0.8 0.0042 16.9 0.5 1.1 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spectrin PF00435.16 EIE80769.1 - 0.0042 17.3 1.9 0.0049 17.1 1.3 1.1 1 0 0 1 1 1 1 Spectrin repeat Herpes_U30 PF04523.8 EIE80769.1 - 0.0078 13.7 1.1 0.0078 13.7 0.8 1.0 1 0 0 1 1 1 1 Herpes virus tegument protein U30 Dak2 PF02734.12 EIE80769.1 - 0.0093 15.6 0.2 0.011 15.4 0.1 1.0 1 0 0 1 1 1 1 DAK2 domain DivIVA PF05103.8 EIE80769.1 - 0.017 15.1 0.5 0.019 14.9 0.3 1.2 1 0 0 1 1 1 0 DivIVA protein DUF3450 PF11932.3 EIE80769.1 - 0.017 14.4 5.6 0.017 14.3 3.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Flagellin_N PF00669.15 EIE80769.1 - 0.021 14.6 4.3 0.025 14.3 3.0 1.1 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region TBPIP PF07106.8 EIE80769.1 - 0.028 13.9 0.3 0.032 13.7 0.2 1.1 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Tektin PF03148.9 EIE80769.1 - 0.032 12.7 2.2 0.039 12.5 1.5 1.1 1 0 0 1 1 1 0 Tektin family Striatin PF08232.7 EIE80769.1 - 0.052 13.8 0.4 0.064 13.5 0.3 1.1 1 0 0 1 1 1 0 Striatin family Mnd1 PF03962.10 EIE80769.1 - 0.055 13.1 0.8 0.056 13.1 0.6 1.1 1 0 0 1 1 1 0 Mnd1 family TPR_MLP1_2 PF07926.7 EIE80769.1 - 0.056 13.1 2.5 0.063 13.0 1.7 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF2203 PF09969.4 EIE80769.1 - 0.079 13.1 0.2 0.1 12.8 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Cast PF10174.4 EIE80769.1 - 0.083 10.9 3.0 0.092 10.7 2.1 1.0 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone HAUS6_N PF14661.1 EIE80769.1 - 0.084 12.2 1.0 0.093 12.0 0.7 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus AATF-Che1 PF13339.1 EIE80769.1 - 0.13 12.4 1.9 0.15 12.1 1.3 1.2 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor TMF_DNA_bd PF12329.3 EIE80769.1 - 0.13 12.0 1.4 0.19 11.5 1.0 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Spc24 PF08286.6 EIE80769.1 - 0.14 11.8 1.1 0.18 11.5 0.8 1.1 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 FliJ PF02050.11 EIE80769.1 - 0.21 11.6 7.6 0.39 10.7 5.3 1.5 1 1 0 1 1 1 0 Flagellar FliJ protein TEX13 PF15186.1 EIE80769.1 - 0.44 10.1 2.6 0.54 9.8 1.8 1.1 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family DivIC PF04977.10 EIE80769.1 - 0.45 10.0 2.7 0.6 9.6 1.9 1.3 1 0 0 1 1 1 0 Septum formation initiator DUF3373 PF11853.3 EIE80769.1 - 0.86 8.0 2.7 1 7.7 1.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) SseC PF04888.7 EIE80769.1 - 5.5 6.2 7.1 6.1 6.0 4.9 1.0 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family TRAM_LAG1_CLN8 PF03798.11 EIE80770.1 - 4.3e-13 49.2 2.2 4.6e-13 49.1 1.5 1.0 1 0 0 1 1 1 1 TLC domain zf-C2H2 PF00096.21 EIE80771.1 - 1.8e-15 56.2 39.7 6.7e-05 22.9 2.2 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIE80771.1 - 4.7e-13 48.4 35.4 0.0006 19.9 2.5 4.5 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EIE80771.1 - 2.1e-08 34.0 3.0 2.1e-08 34.0 2.1 6.1 5 1 0 5 5 5 2 Zinc-finger double domain Ogr_Delta PF04606.7 EIE80771.1 - 0.021 14.5 0.3 1.5 8.5 0.1 2.8 1 1 1 2 2 2 0 Ogr/Delta-like zinc finger zf-C2H2_6 PF13912.1 EIE80771.1 - 0.076 12.9 0.2 0.076 12.9 0.2 4.5 4 1 0 4 4 4 0 C2H2-type zinc finger RPAP2_Rtr1 PF04181.8 EIE80771.1 - 0.22 11.6 5.4 2.3 8.3 0.3 3.2 1 1 2 3 3 3 0 Rtr1/RPAP2 family DUF1644 PF07800.7 EIE80771.1 - 2.3 8.0 13.7 1.6 8.5 3.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1644) IBR PF01485.16 EIE80771.1 - 4.6 7.1 9.9 2.8 7.8 2.1 3.2 1 1 1 2 2 2 0 IBR domain EF-hand_1 PF00036.27 EIE80772.1 - 2.9e-41 135.6 12.7 2.8e-10 38.7 0.5 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EIE80772.1 - 2.1e-36 123.8 5.7 1.2e-20 73.3 0.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EIE80772.1 - 5.9e-32 109.0 13.0 1.1e-15 56.9 0.3 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 EIE80772.1 - 8.9e-31 102.9 6.5 2.7e-09 36.1 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EIE80772.1 - 1.6e-25 87.2 8.8 1.2e-06 27.5 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 EIE80772.1 - 8.1e-14 51.2 0.1 1.1e-06 28.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.4 EIE80772.1 - 3.2e-11 43.2 0.1 2.2e-05 24.4 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EIE80772.1 - 7.1e-09 35.3 2.2 0.00086 19.0 0.1 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EFhand_Ca_insen PF08726.5 EIE80772.1 - 3.9e-06 26.7 0.7 3.9e-06 26.7 0.5 2.3 2 1 0 2 2 2 1 Ca2+ insensitive EF hand UPF0154 PF03672.8 EIE80772.1 - 0.00015 21.2 2.2 0.005 16.4 0.0 3.4 3 1 1 4 4 4 1 Uncharacterised protein family (UPF0154) EF-hand_like PF09279.6 EIE80772.1 - 0.0015 18.5 3.6 0.0052 16.7 0.2 2.7 2 1 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like TerB PF05099.8 EIE80772.1 - 0.0023 17.6 1.8 0.97 9.1 0.0 2.8 1 1 2 3 3 3 2 Tellurite resistance protein TerB DUF1103 PF06513.6 EIE80772.1 - 0.0024 17.3 1.5 0.0029 17.0 1.1 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) Tenui_NCP PF04876.7 EIE80772.1 - 0.0068 15.9 0.6 0.2 11.2 0.0 2.1 1 1 1 2 2 2 1 Tenuivirus major non-capsid protein RNA_pol_Rpb4 PF03874.11 EIE80772.1 - 0.025 14.5 3.6 0.72 9.8 0.2 2.8 3 0 0 3 3 3 0 RNA polymerase Rpb4 DUF2267 PF10025.4 EIE80772.1 - 0.035 14.1 0.0 0.42 10.6 0.0 2.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) DUF853 PF05872.7 EIE80772.1 - 0.052 11.8 0.0 0.11 10.8 0.0 1.5 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Caleosin PF05042.8 EIE80772.1 - 0.094 12.2 0.1 11 5.5 0.0 2.5 1 1 0 2 2 2 0 Caleosin related protein DUF3647 PF12363.3 EIE80772.1 - 0.13 12.4 3.6 11 6.1 0.0 3.0 1 1 2 3 3 3 0 Phage protein DUF3650 PF12368.3 EIE80772.1 - 0.6 9.6 3.8 45 3.6 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3650) EF-hand_10 PF14788.1 EIE80772.1 - 0.68 9.6 5.1 7.8 6.2 0.1 3.4 2 2 2 4 4 4 0 EF hand DUF3018 PF11455.3 EIE80772.1 - 0.79 9.6 4.5 9.7 6.2 0.1 3.2 2 2 1 3 3 3 0 Protein of unknown function (DUF3018) ARD PF03079.9 EIE80773.1 - 7.7e-07 29.1 0.0 8.6e-07 29.0 0.0 1.0 1 0 0 1 1 1 1 ARD/ARD' family LIM PF00412.17 EIE80774.1 - 4.2e-25 87.5 23.9 6.3e-13 48.5 6.5 2.1 2 0 0 2 2 2 2 LIM domain CsbD PF05532.7 EIE80775.1 - 4.4e-16 58.2 12.7 1.7e-12 46.7 1.5 2.0 1 1 1 2 2 2 2 CsbD-like PhaP_Bmeg PF09602.5 EIE80775.1 - 0.0037 17.0 0.5 0.0063 16.3 0.4 1.4 1 1 0 1 1 1 1 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Mito_carr PF00153.22 EIE80776.1 - 2.5e-49 164.9 6.2 5.6e-23 80.4 0.3 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PX PF00787.19 EIE80777.1 - 4e-05 23.3 0.8 7.7e-05 22.4 0.0 1.9 2 0 0 2 2 2 1 PX domain DUF4367 PF14285.1 EIE80777.1 - 0.1 11.9 0.5 0.22 10.8 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4367) ATP-synt_ab PF00006.20 EIE80778.1 - 1.1e-69 234.1 0.0 1.8e-69 233.5 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EIE80778.1 - 6.4e-26 91.0 0.0 1.7e-25 89.7 0.0 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EIE80778.1 - 8.3e-21 73.9 1.3 1.8e-20 72.9 0.4 2.0 1 1 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EIE80778.1 - 2.3e-05 24.1 0.3 9.5e-05 22.2 0.2 2.1 1 1 1 2 2 2 1 HAS barrel domain Actin PF00022.14 EIE80779.1 - 3.2e-121 404.4 0.0 4e-121 404.1 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EIE80779.1 - 0.019 13.6 0.0 0.087 11.4 0.0 1.9 1 1 0 1 1 1 0 MreB/Mbl protein Pkinase PF00069.20 EIE80780.1 - 8.7e-59 198.7 0.0 2.2e-58 197.4 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE80780.1 - 6.4e-25 87.6 0.0 7.5e-24 84.1 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE80780.1 - 0.00035 19.6 0.0 0.5 9.2 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 EIE80780.1 - 0.0087 15.1 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_C13 PF01650.13 EIE80781.1 - 2.2e-44 151.6 2.0 2.7e-44 151.4 1.4 1.0 1 0 0 1 1 1 1 Peptidase C13 family Coatomer_WDAD PF04053.9 EIE80782.1 - 4.6e-141 470.6 0.3 8.4e-141 469.7 0.2 1.4 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.6 EIE80782.1 - 6.4e-112 374.1 0.2 8.3e-112 373.8 0.2 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 EIE80782.1 - 1.6e-54 179.9 11.2 4.4e-11 42.2 0.1 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 EIE80782.1 - 0.023 12.8 8.1 2.3 6.2 0.5 3.9 2 1 1 3 3 3 0 Nucleoporin Nup120/160 HSP70 PF00012.15 EIE80783.1 - 1.6e-273 908.1 8.1 1.9e-273 907.9 5.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EIE80783.1 - 1.6e-15 56.5 0.1 1.4e-14 53.4 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein Hydantoinase_A PF01968.13 EIE80783.1 - 0.0043 16.1 0.1 0.027 13.5 0.1 2.2 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase FGGY_C PF02782.11 EIE80783.1 - 0.0071 15.9 0.0 0.017 14.7 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Prefoldin_2 PF01920.15 EIE80783.1 - 0.024 14.3 5.1 0.1 12.3 3.3 2.2 2 1 0 2 2 2 0 Prefoldin subunit StbA PF06406.6 EIE80783.1 - 0.036 13.0 0.0 0.075 11.9 0.0 1.5 1 0 0 1 1 1 0 StbA protein PolyA_pol PF01743.15 EIE80784.1 - 1.4e-17 64.0 0.1 2.9e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 EIE80784.1 - 3.2e-07 29.7 0.0 7.3e-07 28.6 0.0 1.6 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.1 EIE80784.1 - 0.035 13.9 0.1 0.079 12.7 0.1 1.6 1 1 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative GAGA_bind PF06217.7 EIE80785.1 - 0.016 15.1 3.2 0.018 15.0 2.2 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family Ribosomal_S24e PF01282.14 EIE80786.1 - 3.7e-36 122.7 0.4 5.6e-36 122.2 0.0 1.4 1 1 1 2 2 2 1 Ribosomal protein S24e Ribosomal_S2 PF00318.15 EIE80786.1 - 0.093 11.9 0.5 0.11 11.6 0.4 1.1 1 0 0 1 1 1 0 Ribosomal protein S2 HMA PF00403.21 EIE80787.1 - 0.099 12.8 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 Heavy-metal-associated domain GPW_gp25 PF04965.9 EIE80787.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 Gene 25-like lysozyme Lectin_N PF03954.9 EIE80789.1 - 0.085 12.2 0.1 0.12 11.8 0.1 1.2 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain zf-CCHC_4 PF14392.1 EIE80790.1 - 4 7.1 9.1 4.8 6.9 0.2 2.4 2 0 0 2 2 2 0 Zinc knuckle DUF4611 PF15387.1 EIE80790.1 - 8.6 6.5 11.8 0.28 11.3 1.3 2.7 1 1 0 2 2 2 0 Domain of unknown function (DUF4611) YopR_core PF09025.5 EIE80791.1 - 0.057 13.4 0.0 0.061 13.3 0.0 1.0 1 0 0 1 1 1 0 YopR Core DUF4445 PF14574.1 EIE80792.1 - 0.036 12.3 0.0 0.037 12.2 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4445) SAM_MT PF04445.8 EIE80792.1 - 0.068 12.3 0.0 0.092 11.8 0.0 1.2 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase CLASP_N PF12348.3 EIE80794.1 - 1.5e-23 83.3 0.2 1.9e-23 83.0 0.2 1.1 1 0 0 1 1 1 1 CLASP N terminal TPR_11 PF13414.1 EIE80795.1 - 5.7e-13 48.3 6.2 9.8e-09 34.7 2.1 2.3 1 1 1 2 2 2 2 TPR repeat Lactamase_B PF00753.22 EIE80795.1 - 4.4e-11 42.7 6.5 5e-05 23.0 0.5 2.2 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily TPR_12 PF13424.1 EIE80795.1 - 2e-07 30.8 5.5 0.0003 20.6 2.1 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 EIE80795.1 - 5.5e-06 25.8 7.2 0.01 15.6 0.1 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EIE80795.1 - 8e-05 22.0 3.4 0.0025 17.3 0.1 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 EIE80795.1 - 0.022 14.5 2.4 0.56 10.1 0.0 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF2742 PF10888.3 EIE80795.1 - 0.028 14.3 0.1 0.05 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2742) TPR_8 PF13181.1 EIE80795.1 - 0.031 14.0 0.5 0.031 14.0 0.3 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat FANCI_S2 PF14676.1 EIE80795.1 - 0.044 13.7 0.0 0.069 13.0 0.0 1.2 1 0 0 1 1 1 0 FANCI solenoid 2 TPR_19 PF14559.1 EIE80795.1 - 0.054 13.8 2.2 0.058 13.7 0.3 2.0 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EIE80795.1 - 0.058 13.8 1.0 8.3 7.1 0.0 2.8 1 1 1 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 EIE80795.1 - 1.1 9.4 5.1 7.7 6.7 3.1 2.4 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 eRF1_2 PF03464.10 EIE80796.1 - 6.9e-44 149.4 0.0 1.4e-43 148.4 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 EIE80796.1 - 5.3e-38 129.7 0.1 1.1e-37 128.7 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 EIE80796.1 - 9.6e-24 83.4 0.0 1.6e-23 82.7 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 Ribosomal_L7Ae PF01248.21 EIE80796.1 - 0.13 11.7 0.0 0.36 10.3 0.0 1.7 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family MFS_1 PF07690.11 EIE80797.1 - 7.3e-35 120.3 14.2 8.9e-35 120.0 9.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily RseC_MucC PF04246.7 EIE80797.1 - 9.7 5.7 6.8 7.7 6.0 0.4 2.5 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DASH_Duo1 PF08651.5 EIE80798.1 - 9.8e-14 50.6 2.5 1.3e-13 50.2 1.7 1.2 1 0 0 1 1 1 1 DASH complex subunit Duo1 CbiM PF01891.11 EIE80799.1 - 0.00055 19.5 1.6 0.00055 19.5 1.1 1.6 2 0 0 2 2 2 1 Cobalt uptake substrate-specific transmembrane region Kei1 PF08552.6 EIE80799.1 - 0.0071 16.0 4.0 0.013 15.2 2.8 1.6 1 1 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 Abhydrolase_1 PF00561.15 EIE80799.1 - 0.032 13.7 0.0 0.056 12.9 0.0 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold Asp PF00026.18 EIE80800.1 - 6.5e-44 150.4 0.0 7.6e-44 150.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIE80800.1 - 0.00032 20.7 0.1 0.0011 18.9 0.0 1.8 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EIE80800.1 - 0.0021 18.4 0.0 0.016 15.6 0.0 2.3 2 1 0 2 2 2 1 Aspartyl protease Ribosomal_L34e PF01199.13 EIE80801.1 - 7.4e-41 138.2 6.0 9.2e-41 137.9 4.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L34e GFA PF04828.9 EIE80801.1 - 0.093 12.6 0.7 0.33 10.9 0.0 1.9 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Nodulin-like PF06813.8 EIE80802.1 - 5.4e-07 29.1 3.7 8.5e-07 28.4 2.6 1.3 1 0 0 1 1 1 1 Nodulin-like DEAD PF00270.24 EIE80803.1 - 3.7e-05 23.2 0.0 8.6e-05 22.0 0.0 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase L51_S25_CI-B8 PF05047.11 EIE80806.1 - 2.5e-12 46.3 0.2 3.7e-12 45.7 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Acyltransferase PF01553.16 EIE80807.1 - 1.7e-05 24.2 0.0 4.3e-05 22.9 0.0 1.7 1 1 0 1 1 1 1 Acyltransferase VQ PF05678.9 EIE80808.1 - 0.024 13.6 0.2 0.038 13.0 0.1 1.3 1 0 0 1 1 1 0 VQ motif DUF805 PF05656.9 EIE80808.1 - 0.13 12.1 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF805) rve PF00665.21 EIE80809.1 - 1.7e-25 89.4 0.0 2.6e-25 88.8 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 EIE80809.1 - 0.0021 17.5 0.0 0.0078 15.7 0.0 2.1 1 1 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE80810.1 - 2.7e-16 59.5 0.0 5.2e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 EIE80810.1 - 0.13 12.5 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 RNase H DDE_3 PF13358.1 EIE80811.1 - 4.3e-21 75.2 0.4 5.9e-21 74.7 0.3 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease UBN2 PF14223.1 EIE80812.1 - 0.0083 15.9 0.2 0.021 14.6 0.0 1.8 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 EIE80812.1 - 0.016 14.7 0.0 0.038 13.5 0.0 1.6 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type rve PF00665.21 EIE80815.1 - 1e-20 74.0 0.0 6.2e-20 71.5 0.0 2.2 3 0 0 3 3 3 1 Integrase core domain Chromo PF00385.19 EIE80815.1 - 6.7e-07 28.8 2.1 1.6e-06 27.7 1.4 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve_3 PF13683.1 EIE80815.1 - 0.0066 15.9 0.0 0.022 14.2 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain Tudor-knot PF11717.3 EIE80815.1 - 0.018 14.7 0.7 0.069 12.8 0.5 2.0 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain HTH_23 PF13384.1 EIE80816.1 - 0.025 14.2 0.0 0.051 13.2 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain FNIP_C PF14638.1 EIE80816.1 - 0.099 11.9 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Folliculin-interacting protein C-terminus DDE_3 PF13358.1 EIE80817.1 - 3.2e-20 72.3 0.4 7.9e-20 71.0 0.3 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE80817.1 - 3.7e-10 39.7 0.9 3.7e-10 39.7 0.6 2.3 2 0 0 2 2 2 1 Transposase HTH_38 PF13936.1 EIE80817.1 - 0.00047 19.6 0.1 0.0011 18.4 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain MarR PF01047.17 EIE80817.1 - 0.005 16.5 0.1 0.23 11.1 0.0 2.7 3 0 0 3 3 3 1 MarR family HTH_23 PF13384.1 EIE80817.1 - 0.0053 16.3 0.6 0.019 14.6 0.0 2.1 2 0 0 2 2 2 1 Homeodomain-like domain Sigma54_DBD PF04552.8 EIE80817.1 - 0.064 12.7 0.1 0.22 11.0 0.0 1.9 1 1 1 2 2 2 0 Sigma-54, DNA binding domain TrmB PF01978.14 EIE80817.1 - 0.083 12.6 0.8 1.3 8.7 0.0 2.8 2 1 1 3 3 3 0 Sugar-specific transcriptional regulator TrmB HTH_32 PF13565.1 EIE80817.1 - 0.14 12.9 1.7 41 5.0 0.0 3.5 2 1 1 3 3 3 0 Homeodomain-like domain LacI PF00356.16 EIE80817.1 - 0.17 11.5 0.4 0.6 9.7 0.0 2.1 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family DDE_Tnp_IS1595 PF12762.2 EIE80818.1 - 7.3e-23 81.0 0.9 1.3e-22 80.3 0.4 1.6 2 0 0 2 2 2 1 ISXO2-like transposase domain Exo_endo_phos_2 PF14529.1 EIE80819.1 - 4.2e-19 68.3 0.0 7.5e-19 67.4 0.0 1.4 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EIE80819.1 - 1.2e-05 25.3 0.1 3.9e-05 23.7 0.0 1.8 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Mod_r PF07200.8 EIE80820.1 - 0.00027 20.8 0.1 0.00051 19.9 0.1 1.4 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Matrilin_ccoil PF10393.4 EIE80820.1 - 0.023 14.0 0.2 0.05 12.9 0.2 1.5 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin Reo_sigmaC PF04582.7 EIE80820.1 - 0.068 12.3 1.1 0.1 11.7 0.8 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein TMF_DNA_bd PF12329.3 EIE80820.1 - 0.14 11.9 4.0 1.5 8.6 1.4 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding LacI PF00356.16 EIE80820.1 - 0.36 10.4 2.5 1.2 8.7 0.0 2.7 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family DDE_3 PF13358.1 EIE80821.1 - 1.1e-30 106.3 0.0 1.6e-30 105.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.14 EIE80821.1 - 0.00048 19.3 0.3 0.0022 17.1 0.2 1.9 1 1 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE80821.1 - 0.021 14.9 0.0 0.04 14.0 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain HTH_29 PF13551.1 EIE80822.1 - 8e-06 25.9 0.0 1e-05 25.6 0.0 1.1 1 0 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.1 EIE80822.1 - 8.1e-06 26.5 0.0 1.1e-05 26.1 0.0 1.1 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.1 EIE80822.1 - 6.3e-05 22.8 0.0 9.9e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_psq PF05225.11 EIE80822.1 - 0.00027 20.4 0.0 0.00047 19.6 0.0 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_23 PF13384.1 EIE80822.1 - 0.0024 17.4 0.0 0.0051 16.4 0.0 1.5 2 0 0 2 2 2 1 Homeodomain-like domain DUF1804 PF08822.6 EIE80822.1 - 0.0064 16.2 1.0 0.0086 15.8 0.7 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1804) HTH_1 PF00126.22 EIE80822.1 - 0.019 14.6 0.0 0.044 13.5 0.0 1.6 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family NUMOD1 PF07453.8 EIE80822.1 - 0.029 14.2 0.0 0.054 13.3 0.0 1.4 1 0 0 1 1 1 0 NUMOD1 domain HTH_17 PF12728.2 EIE80822.1 - 0.057 13.6 0.0 0.61 10.3 0.0 2.6 2 1 0 2 2 2 0 Helix-turn-helix domain DUF3486 PF11985.3 EIE80822.1 - 0.062 13.3 0.0 0.081 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3486) CENP-B_N PF04218.8 EIE80822.1 - 0.11 11.8 0.1 0.28 10.6 0.0 1.7 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain Chromo PF00385.19 EIE80823.1 - 8.8e-07 28.5 2.4 1.2e-06 28.0 0.3 2.1 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain ThiS-like PF14453.1 EIE80823.1 - 0.05 13.4 1.1 0.71 9.7 0.3 2.6 2 0 0 2 2 2 0 ThiS-like ubiquitin TNV_CP PF03898.8 EIE80824.1 - 0.083 11.9 0.0 0.083 11.9 0.0 1.1 1 0 0 1 1 1 0 Satellite tobacco necrosis virus coat protein PPR_3 PF13812.1 EIE80825.1 - 2.3e-09 36.8 0.1 0.21 11.9 0.0 5.9 7 0 0 7 7 7 3 Pentatricopeptide repeat domain PPR PF01535.15 EIE80825.1 - 9.3e-07 28.4 3.0 2.7 8.1 0.0 6.0 7 0 0 7 7 7 3 PPR repeat PPR_2 PF13041.1 EIE80825.1 - 4e-06 26.7 5.2 0.18 11.8 0.0 5.2 6 0 0 6 6 6 2 PPR repeat family MNE1 PF13762.1 EIE80825.1 - 0.0015 18.6 0.5 0.045 13.8 0.0 2.9 1 1 1 2 2 2 1 Mitochondrial splicing apparatus component Septin PF00735.13 EIE80826.1 - 1.6e-103 345.6 0.6 2e-103 345.2 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 EIE80826.1 - 0.00025 20.9 0.0 0.00075 19.4 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EIE80826.1 - 0.084 12.6 2.2 1.2 8.9 0.0 2.9 2 1 1 3 3 3 0 Dynamin family FMN_bind PF04205.9 EIE80826.1 - 0.09 12.9 1.9 0.6 10.3 0.0 2.5 2 1 0 2 2 2 0 FMN-binding domain RF-1 PF00472.15 EIE80826.1 - 0.1 12.4 2.8 0.25 11.1 1.9 1.7 1 1 0 1 1 1 0 RF-1 domain Pkinase PF00069.20 EIE80827.1 - 1.1e-52 178.7 0.0 1.2e-50 172.1 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIE80827.1 - 4.9e-27 94.6 0.0 6.3e-27 94.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase YrbL-PhoP_reg PF10707.4 EIE80827.1 - 0.065 12.5 0.0 0.4 9.9 0.0 2.0 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Kinase-like PF14531.1 EIE80827.1 - 0.068 12.1 0.0 0.16 10.8 0.0 1.6 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.9 EIE80827.1 - 0.12 11.4 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family tRNA_m1G_MT PF01746.16 EIE80828.1 - 1e-36 126.2 0.6 1.2e-36 126.0 0.4 1.1 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase NUC173 PF08161.7 EIE80829.1 - 1.2e-59 201.0 8.1 2e-59 200.3 0.0 4.2 5 0 0 5 5 5 2 NUC173 domain DDE_3 PF13358.1 EIE80830.1 - 2.8e-13 49.8 0.0 3.6e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Toprim_N PF08275.6 EIE80830.1 - 0.13 12.1 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 DNA primase catalytic core, N-terminal domain CC PF04942.9 EIE80831.1 - 0.056 13.3 0.6 0.056 13.3 0.4 2.3 2 1 0 2 2 2 0 CC domain Cgr1 PF03879.9 EIE80832.1 - 6.8e-09 35.8 7.7 8.7e-09 35.5 5.3 1.1 1 0 0 1 1 1 1 Cgr1 family Clr2 PF10383.4 EIE80832.1 - 0.086 12.8 0.7 0.098 12.6 0.5 1.1 1 0 0 1 1 1 0 Transcription-silencing protein Clr2 DUF1609 PF07753.6 EIE80832.1 - 0.089 12.1 4.3 0.084 12.1 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1609) DUF572 PF04502.8 EIE80832.1 - 0.79 8.8 8.2 0.89 8.7 5.2 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF572) GTP_EFTU PF00009.22 EIE80833.1 - 9.7e-41 139.2 0.0 1.5e-40 138.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EIE80833.1 - 1.3e-22 79.5 0.0 6.2e-22 77.4 0.0 2.2 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 EIE80833.1 - 2.4e-22 78.5 0.0 2.3e-21 75.4 0.0 2.6 3 0 0 3 3 3 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EIE80833.1 - 4.5e-10 39.5 0.1 1e-09 38.3 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EIE80833.1 - 8.2e-07 28.7 0.0 1.9e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 EIE80833.1 - 4.4e-05 23.3 0.2 0.00011 22.0 0.1 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EIE80833.1 - 0.0001 22.7 0.1 0.00029 21.3 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein Dynamin_N PF00350.18 EIE80833.1 - 0.088 12.6 0.1 2.2 8.1 0.0 2.5 1 1 1 2 2 2 0 Dynamin family Ebp2 PF05890.7 EIE80835.1 - 3.3e-60 203.6 23.1 3.3e-60 203.6 16.0 1.6 2 0 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 Daxx PF03344.10 EIE80835.1 - 8 4.8 25.2 9.9 4.5 17.5 1.1 1 0 0 1 1 1 0 Daxx Family CtsR PF05848.6 EIE80836.1 - 0.054 13.4 0.1 0.075 12.9 0.1 1.2 1 0 0 1 1 1 0 Firmicute transcriptional repressor of class III stress genes (CtsR) TIMELESS PF04821.9 EIE80837.1 - 2.4e-24 86.0 0.0 3.4e-24 85.5 0.0 1.1 1 0 0 1 1 1 1 Timeless protein YusW PF14039.1 EIE80837.1 - 0.0052 17.0 0.0 0.0084 16.3 0.0 1.3 1 0 0 1 1 1 1 YusW-like protein TIMELESS PF04821.9 EIE80838.1 - 0.00013 21.3 0.1 0.00013 21.3 0.1 1.8 2 0 0 2 2 2 1 Timeless protein CBS PF00571.23 EIE80839.1 - 6e-11 41.9 5.4 4.2e-05 23.2 0.1 3.6 3 1 1 4 4 4 3 CBS domain CTK3 PF12243.3 EIE80839.1 - 0.12 11.9 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 Ribosomal_S11 PF00411.14 EIE80840.1 - 1.1e-22 80.2 0.1 1.5e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S11 zf-met PF12874.2 EIE80841.1 - 2.7e-07 30.5 2.9 3.4e-07 30.2 1.2 1.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.4 EIE80841.1 - 0.00027 20.5 0.9 0.00042 19.8 0.6 1.3 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein PRP4 PF08799.6 EIE80841.1 - 0.038 13.2 0.6 0.061 12.6 0.4 1.3 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like PTR2 PF00854.16 EIE80842.1 - 1.6e-48 165.4 7.4 2.4e-47 161.5 5.1 2.1 1 1 0 1 1 1 1 POT family MFS_1 PF07690.11 EIE80842.1 - 0.0022 16.7 12.4 0.0078 14.9 8.6 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Aa_trans PF01490.13 EIE80843.1 - 2.4e-56 190.9 32.8 3.3e-55 187.2 22.8 1.9 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.1 EIE80843.1 - 3.2e-12 45.7 29.4 5e-12 45.0 20.4 1.2 1 0 0 1 1 1 1 Amino acid permease Glyco_hydro_18 PF00704.23 EIE80845.1 - 1.8e-58 198.6 4.9 3.6e-56 191.0 3.4 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 ubiquitin PF00240.18 EIE80846.1 - 5e-35 118.7 1.3 6.5e-35 118.3 0.9 1.1 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.12 EIE80846.1 - 9.8e-31 105.1 11.1 1.6e-30 104.4 7.7 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.3 EIE80846.1 - 2.5e-20 71.9 1.0 4e-20 71.2 0.7 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EIE80846.1 - 2.9e-06 27.4 0.2 1e-05 25.6 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EIE80846.1 - 0.00011 21.9 0.0 0.00016 21.4 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EIE80846.1 - 0.003 17.4 0.1 0.0058 16.4 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EIE80846.1 - 0.0045 17.1 0.1 0.0046 17.1 0.0 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 EIE80846.1 - 0.091 12.8 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2870) Plexin_cytopl PF08337.7 EIE80846.1 - 0.16 10.2 0.7 2.8 6.1 0.3 2.0 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain Fer2_3 PF13085.1 EIE80846.1 - 0.22 11.3 2.0 0.92 9.3 0.9 2.1 1 1 1 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain Clathrin PF00637.15 EIE80847.1 - 5.6e-24 84.3 0.8 5.6e-24 84.3 0.6 2.7 3 0 0 3 3 3 1 Region in Clathrin and VPS WD40 PF00400.27 EIE80847.1 - 2.7e-08 33.3 0.0 4.4e-06 26.3 0.0 3.3 4 0 0 4 4 4 1 WD domain, G-beta repeat Vps39_2 PF10367.4 EIE80847.1 - 0.04 14.1 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.4 EIE80847.1 - 0.065 13.2 2.3 0.27 11.2 0.1 2.7 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 DAO PF01266.19 EIE80848.1 - 5.7e-53 180.0 0.0 7e-53 179.7 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIE80848.1 - 7.9e-05 22.6 0.1 0.00019 21.3 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EIE80848.1 - 0.00051 19.9 1.1 0.006 16.4 0.7 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EIE80848.1 - 0.0012 18.0 0.0 0.0025 16.9 0.0 1.5 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.14 EIE80848.1 - 0.0015 17.6 0.3 0.031 13.3 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 EIE80848.1 - 0.0021 18.1 0.2 0.01 15.9 0.1 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.10 EIE80848.1 - 0.0035 15.5 0.0 0.071 11.2 0.0 2.0 2 0 0 2 2 2 1 Malate:quinone oxidoreductase (Mqo) Lycopene_cycl PF05834.7 EIE80848.1 - 0.0049 15.8 0.1 0.0092 14.9 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EIE80848.1 - 0.0098 14.7 0.4 0.015 14.1 0.3 1.5 1 1 0 1 1 1 1 FAD binding domain Reprolysin_4 PF13583.1 EIE80848.1 - 0.021 14.3 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like NAD_binding_9 PF13454.1 EIE80848.1 - 0.028 14.1 0.1 0.053 13.3 0.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 EIE80848.1 - 0.063 11.8 0.3 0.091 11.3 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_7 PF13241.1 EIE80848.1 - 0.07 13.4 0.1 0.22 11.7 0.0 2.0 1 1 0 1 1 1 0 Putative NAD(P)-binding TrkA_N PF02254.13 EIE80848.1 - 0.078 12.9 0.8 0.16 11.9 0.1 1.8 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox PF00070.22 EIE80848.1 - 0.079 13.3 0.1 0.18 12.1 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Saccharop_dh PF03435.13 EIE80848.1 - 0.1 11.5 0.8 0.22 10.4 0.1 1.9 3 0 0 3 3 3 0 Saccharopine dehydrogenase GATA PF00320.22 EIE80849.1 - 8.5e-32 108.2 20.0 1.6e-16 59.3 1.9 2.5 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 EIE80849.1 - 5e-05 22.5 9.5 0.0061 15.8 0.9 2.9 2 1 1 3 3 3 3 TFIIB zinc-binding ArfGap PF01412.13 EIE80849.1 - 9.4e-05 22.1 5.9 0.015 15.0 0.3 2.3 2 0 0 2 2 2 2 Putative GTPase activating protein for Arf Mito_morph_reg PF14972.1 EIE80849.1 - 0.037 13.4 1.0 0.33 10.3 0.4 2.0 2 0 0 2 2 2 0 Mitochondrial morphogenesis regulator RRN7 PF11781.3 EIE80849.1 - 0.043 13.3 4.6 2.5 7.6 0.2 2.8 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 Zn-ribbon_8 PF09723.5 EIE80849.1 - 0.12 12.3 6.7 3 7.8 0.1 3.3 3 0 0 3 3 3 0 Zinc ribbon domain FYVE PF01363.16 EIE80849.1 - 0.41 10.5 10.1 1.3 8.9 4.4 3.2 2 1 0 2 2 2 0 FYVE zinc finger DUF2318 PF10080.4 EIE80849.1 - 0.84 9.4 9.0 4.6 7.0 0.6 3.8 2 1 1 3 3 3 0 Predicted membrane protein (DUF2318) zf-C2H2_3 PF13878.1 EIE80849.1 - 1 8.9 12.9 3.1 7.4 0.1 4.4 5 0 0 5 5 5 0 zinc-finger of acetyl-transferase ESCO DZR PF12773.2 EIE80849.1 - 1.7 8.4 17.8 25 4.7 9.0 3.6 2 1 0 2 2 2 0 Double zinc ribbon NMD3 PF04981.8 EIE80849.1 - 2 7.4 9.0 0.68 9.0 0.2 2.5 3 0 0 3 3 3 0 NMD3 family eIF-5_eIF-2B PF01873.12 EIE80849.1 - 3.2 7.4 11.5 1.7 8.3 0.3 2.7 3 0 0 3 3 3 0 Domain found in IF2B/IF5 zf-ribbon_3 PF13248.1 EIE80849.1 - 6.1 6.1 18.3 1.1 8.5 0.6 3.6 3 2 1 4 4 4 0 zinc-ribbon domain COX5B PF01215.14 EIE80849.1 - 7.8 6.1 8.6 6.2 6.5 0.2 3.6 2 2 1 3 3 3 0 Cytochrome c oxidase subunit Vb Prim_Zn_Ribbon PF08273.7 EIE80849.1 - 8.3 6.5 11.4 19 5.4 1.7 3.0 2 2 0 2 2 2 0 Zinc-binding domain of primase-helicase zf-C2H2 PF00096.21 EIE80850.1 - 4.4e-15 55.0 16.6 0.00012 22.1 0.7 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type Myb_DNA-binding PF00249.26 EIE80850.1 - 1.7e-14 53.5 1.2 6.5e-14 51.7 0.6 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain zf-H2C2_2 PF13465.1 EIE80850.1 - 6.1e-14 51.5 14.5 1.3e-06 28.3 0.4 4.0 4 0 0 4 4 4 2 Zinc-finger double domain Myb_DNA-bind_6 PF13921.1 EIE80850.1 - 1.3e-12 47.6 2.2 3e-12 46.4 0.5 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain zf-C2H2_4 PF13894.1 EIE80850.1 - 2.1e-09 37.0 16.6 0.0076 16.5 0.5 4.0 4 0 0 4 4 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EIE80850.1 - 0.0004 20.1 8.5 0.017 15.0 0.7 3.4 3 0 0 3 3 3 1 C2H2-type zinc finger SLIDE PF09111.5 EIE80850.1 - 0.029 14.0 0.1 0.075 12.7 0.0 1.7 1 0 0 1 1 1 0 SLIDE CHDCT2 PF08074.6 EIE80850.1 - 0.036 13.7 0.7 0.32 10.7 0.0 2.6 2 0 0 2 2 2 0 CHDCT2 (NUC038) domain Zn_Tnp_IS1595 PF12760.2 EIE80850.1 - 0.087 12.6 12.1 0.029 14.1 3.1 3.4 3 1 1 4 4 4 0 Transposase zinc-ribbon domain zf-C2H2_jaz PF12171.3 EIE80850.1 - 0.18 11.9 10.7 2.2 8.5 0.1 4.4 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.5 EIE80850.1 - 0.22 11.5 6.3 5.4 7.0 0.8 3.0 1 1 2 3 3 3 0 Zinc ribbon domain Zn_Tnp_IS1 PF03811.8 EIE80850.1 - 1.4 8.4 4.6 3.7 7.1 3.2 1.8 1 0 0 1 1 1 0 InsA N-terminal domain zf-met PF12874.2 EIE80850.1 - 1.6 9.0 16.4 3.7 7.8 0.2 4.5 4 0 0 4 4 4 0 Zinc-finger of C2H2 type C1_4 PF07975.7 EIE80850.1 - 3 7.9 6.4 2.4 8.2 2.1 2.4 1 1 0 1 1 1 0 TFIIH C1-like domain DUF605 PF04652.11 EIE80850.1 - 6.2 6.1 40.1 0.84 8.9 20.6 2.1 2 0 0 2 2 2 0 Vta1 like Cullin PF00888.17 EIE80851.1 - 1.2e-124 417.0 25.1 1.5e-124 416.7 17.4 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EIE80851.1 - 7.3e-06 25.7 0.7 2.5e-05 24.0 0.5 2.0 1 0 0 1 1 1 1 Cullin protein neddylation domain Glyco_hydro_20 PF00728.17 EIE80852.1 - 1.5e-91 307.2 0.1 2.6e-91 306.4 0.1 1.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 EIE80852.1 - 4.1e-19 69.5 0.0 9.1e-19 68.3 0.0 1.6 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 EIE80852.1 - 1.4e-07 32.1 0.0 4.4e-07 30.4 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 GHL6 PF14871.1 EIE80852.1 - 0.017 15.1 0.0 0.047 13.7 0.0 1.7 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase 6 DUF4434 PF14488.1 EIE80852.1 - 0.027 14.2 0.3 12 5.5 0.0 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4434) DUF2187 PF09953.4 EIE80852.1 - 0.058 13.1 0.1 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2187) DTW PF03942.10 EIE80853.1 - 6.2e-09 35.3 0.0 6.9e-09 35.2 0.0 1.0 1 0 0 1 1 1 1 DTW domain CybS PF05328.7 EIE80854.1 - 3.2e-35 120.6 0.0 4.4e-35 120.2 0.0 1.2 1 0 0 1 1 1 1 CybS GST_C PF00043.20 EIE80855.1 - 3.3e-09 36.6 0.1 5.9e-09 35.8 0.1 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EIE80855.1 - 2.9e-08 33.8 0.0 5.3e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIE80855.1 - 4.5e-08 32.8 0.0 6.3e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EIE80855.1 - 1.4e-06 28.3 0.0 2.6e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EIE80855.1 - 0.00026 21.3 0.0 0.00041 20.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EIE80855.1 - 0.00081 19.3 0.0 0.0015 18.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Inhibitor_G39P PF11417.3 EIE80855.1 - 0.11 12.4 0.4 0.57 10.1 0.0 2.2 2 0 0 2 2 2 0 Loader and inhibitor of phage G40P Na_Ca_ex PF01699.19 EIE80856.1 - 1.8e-39 134.5 39.4 5.1e-22 77.9 7.3 3.0 2 1 1 3 3 3 2 Sodium/calcium exchanger protein GAGA_bind PF06217.7 EIE80857.1 - 0.015 15.2 0.7 0.018 15.0 0.5 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family Sec23_trunk PF04811.10 EIE80858.1 - 4.5e-64 216.1 0.0 7.5e-64 215.3 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EIE80858.1 - 4.1e-21 74.3 0.0 7.7e-21 73.4 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EIE80858.1 - 3.5e-17 62.6 0.0 1.3e-16 60.8 0.0 2.1 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EIE80858.1 - 6.6e-15 54.3 6.0 1.4e-14 53.3 4.2 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EIE80858.1 - 2.2e-12 46.5 0.0 4.2e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat Pkinase PF00069.20 EIE80859.1 - 3.3e-11 42.8 0.0 6.9e-11 41.7 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE80859.1 - 0.00025 20.2 0.0 0.00047 19.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HrpB7 PF09486.5 EIE80859.1 - 0.11 12.4 2.3 0.45 10.4 1.0 2.1 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) DUF3450 PF11932.3 EIE80859.1 - 0.56 9.4 5.4 0.95 8.6 3.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Zn_clus PF00172.13 EIE80860.1 - 1.2e-14 53.9 24.4 4.3e-10 39.3 4.6 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Na_trans_assoc PF06512.8 EIE80860.1 - 0.032 14.2 0.4 0.065 13.2 0.2 1.4 1 0 0 1 1 1 0 Sodium ion transport-associated HMG_box PF00505.14 EIE80861.1 - 5.9e-10 39.2 0.3 5.9e-10 39.2 0.2 2.6 3 1 0 3 3 3 1 HMG (high mobility group) box Secretogranin_V PF05281.6 EIE80861.1 - 3.2 7.0 13.2 1.2 8.4 2.1 2.2 2 0 0 2 2 2 0 Neuroendocrine protein 7B2 precursor (Secretogranin V) Astro_capsid PF03115.9 EIE80861.1 - 3.4 5.8 11.6 4 5.5 8.0 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Pkinase PF00069.20 EIE80862.1 - 5.9e-22 78.0 0.0 9.5e-22 77.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kelch_3 PF13415.1 EIE80862.1 - 4.7e-16 58.4 15.0 2.5e-07 30.6 0.3 4.7 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_5 PF13854.1 EIE80862.1 - 3.5e-15 55.5 7.1 5.1e-07 29.5 0.1 4.5 4 0 0 4 4 4 4 Kelch motif Kelch_4 PF13418.1 EIE80862.1 - 7.8e-13 47.9 14.2 3.1e-07 30.0 0.5 4.5 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_6 PF13964.1 EIE80862.1 - 1.1e-10 41.2 12.9 1.2e-05 25.2 0.4 4.7 4 0 0 4 4 4 4 Kelch motif Kelch_2 PF07646.10 EIE80862.1 - 1.1e-10 40.8 8.8 1.7e-05 24.4 0.6 4.3 4 0 0 4 4 4 3 Kelch motif Kelch_1 PF01344.20 EIE80862.1 - 4.2e-09 35.7 17.2 0.0033 16.9 1.7 4.5 4 0 0 4 4 4 3 Kelch motif Pkinase_Tyr PF07714.12 EIE80862.1 - 7.6e-05 21.9 0.1 0.00011 21.3 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase TMEM51 PF15345.1 EIE80862.1 - 0.00058 19.6 0.0 0.0013 18.4 0.0 1.6 1 0 0 1 1 1 1 Transmembrane protein 51 EphA2_TM PF14575.1 EIE80862.1 - 0.0027 18.0 0.0 0.0059 16.9 0.0 1.6 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Kinase-like PF14531.1 EIE80862.1 - 0.013 14.4 0.0 0.021 13.7 0.0 1.2 1 0 0 1 1 1 0 Kinase-like RRM_1 PF00076.17 EIE80863.1 - 9.5e-33 111.6 5.5 1.4e-16 59.8 0.5 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE80863.1 - 1.5e-27 95.3 0.6 6.1e-14 51.7 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE80863.1 - 1e-15 57.2 0.5 2.2e-07 30.5 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Myc_N PF01056.13 EIE80863.1 - 0.009 15.2 5.9 0.009 15.2 4.1 1.7 2 0 0 2 2 2 1 Myc amino-terminal region DUF3721 PF12518.3 EIE80863.1 - 0.41 10.2 1.5 0.88 9.2 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function PX PF00787.19 EIE80864.1 - 6.3e-24 83.9 0.8 1.8e-23 82.5 0.5 1.8 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 EIE80864.1 - 3.1e-10 39.7 5.9 4.1e-06 26.2 0.4 2.8 3 0 0 3 3 3 2 Vps5 C terminal like BAR_3_WASP_bdg PF10456.4 EIE80864.1 - 0.0016 17.7 2.2 0.0033 16.7 0.3 2.3 2 1 0 2 2 2 1 WASP-binding domain of Sorting nexin protein BAR PF03114.13 EIE80864.1 - 0.015 14.8 4.8 1.1 8.7 0.4 2.4 2 0 0 2 2 2 0 BAR domain Peptidase_C10 PF01640.12 EIE80864.1 - 0.03 14.0 0.1 0.061 13.0 0.1 1.5 1 0 0 1 1 1 0 Peptidase C10 family DUF2535 PF10751.4 EIE80864.1 - 0.074 13.2 3.0 0.9 9.7 0.0 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF2535) OmpH PF03938.9 EIE80864.1 - 0.28 11.1 4.2 3.1 7.7 0.0 2.5 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF1451 PF07295.6 EIE80864.1 - 0.41 10.4 5.1 0.99 9.1 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1451) Lipoprotein_X PF03305.8 EIE80867.1 - 0.088 12.1 0.1 0.092 12.1 0.1 1.2 1 0 0 1 1 1 0 Mycoplasma MG185/MG260 protein TEA PF01285.13 EIE80868.1 - 0.0066 15.6 0.3 0.01 15.0 0.2 1.5 1 1 0 1 1 1 1 TEA/ATTS domain family Solute_trans_a PF03619.11 EIE80869.1 - 1e-29 103.7 11.6 4.7e-18 65.4 4.4 2.1 1 1 1 2 2 2 2 Organic solute transporter Ostalpha AAA_23 PF13476.1 EIE80869.1 - 0.02 15.2 0.4 0.028 14.7 0.3 1.1 1 0 0 1 1 1 0 AAA domain DUF3112 PF11309.3 EIE80869.1 - 0.84 9.4 11.4 1.9 8.2 0.2 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3112) DUF2673 PF10880.3 EIE80870.1 - 0.068 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2673) DUF336 PF03928.9 EIE80871.1 - 4.7e-25 87.9 0.0 5.4e-25 87.7 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF336) Cas_Cmr5 PF09701.5 EIE80871.1 - 0.11 12.6 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cmr5) AA_permease_2 PF13520.1 EIE80873.1 - 1e-60 205.5 42.3 1.3e-60 205.1 29.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EIE80873.1 - 3e-33 114.8 37.4 3.7e-33 114.6 25.9 1.0 1 0 0 1 1 1 1 Amino acid permease Peptidase_M56 PF05569.6 EIE80873.1 - 0.66 8.8 6.5 0.1 11.5 1.3 1.9 2 1 0 2 2 2 0 BlaR1 peptidase M56 Nup88 PF10168.4 EIE80874.1 - 1.4e-17 62.8 7.4 1.5e-08 32.9 4.2 2.3 2 1 0 2 2 2 2 Nuclear pore component Sbi-IV PF11621.3 EIE80874.1 - 0.014 15.5 0.8 0.39 10.8 0.0 2.6 2 0 0 2 2 2 0 C3 binding domain 4 of IgG-bind protein SBI OmpH PF03938.9 EIE80874.1 - 2.1 8.2 8.3 4.5 7.1 5.7 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) GDI PF00996.13 EIE80875.1 - 6.6e-192 637.6 0.1 7.7e-192 637.4 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Metallophos PF00149.23 EIE80876.1 - 1.1e-07 31.4 4.9 2e-07 30.6 3.4 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase EF-hand_4 PF12763.2 EIE80877.1 - 1.2e-25 89.2 0.2 2.3e-12 46.5 0.0 3.2 3 0 0 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 EIE80877.1 - 5e-07 29.7 0.0 0.00048 20.1 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EIE80877.1 - 3.9e-06 25.7 0.0 0.00067 18.7 0.0 2.7 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 EIE80877.1 - 0.00067 19.3 0.1 0.37 10.8 0.0 3.3 3 0 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.1 EIE80877.1 - 0.0018 17.8 0.0 1.7 8.3 0.0 2.7 2 1 0 2 2 2 2 EF-hand domain pair DUF489 PF04356.7 EIE80877.1 - 0.071 12.6 17.8 0.75 9.3 8.6 3.0 3 1 1 4 4 4 0 Protein of unknown function (DUF489) V_ATPase_I PF01496.14 EIE80877.1 - 0.85 7.3 19.3 1.4 6.7 13.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Reo_sigmaC PF04582.7 EIE80877.1 - 1.4 8.0 7.4 1.9 7.5 4.6 1.5 1 1 0 1 1 1 0 Reovirus sigma C capsid protein CorA PF01544.13 EIE80877.1 - 1.4 7.8 7.6 2.9 6.8 5.3 1.5 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Pox_A_type_inc PF04508.7 EIE80877.1 - 1.8 8.5 6.6 0.3 10.9 0.5 2.9 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat AAA_13 PF13166.1 EIE80877.1 - 3.5 5.9 30.9 5 5.4 21.4 1.1 1 0 0 1 1 1 0 AAA domain DUF1409 PF07197.7 EIE80877.1 - 3.7 7.6 11.7 2.6 8.1 3.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1409) Adaptin_N PF01602.15 EIE80878.1 - 1.5e-117 393.1 4.6 2e-117 392.7 3.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 EIE80878.1 - 1.7e-57 193.5 3.3 3.5e-57 192.4 2.3 1.6 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 EIE80878.1 - 2.5e-16 59.7 1.6 0.0025 18.0 0.0 5.7 4 1 1 6 6 6 4 HEAT repeats HEAT_EZ PF13513.1 EIE80878.1 - 0.00027 21.3 1.1 0.099 13.1 0.1 4.0 3 0 0 3 3 3 1 HEAT-like repeat HEAT PF02985.17 EIE80878.1 - 0.0062 16.5 9.7 5.3 7.3 0.0 6.2 8 0 0 8 8 8 2 HEAT repeat DUF3730 PF12530.3 EIE80878.1 - 0.049 13.5 2.9 3.8 7.3 0.1 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF3730) HEAT_PBS PF03130.11 EIE80878.1 - 0.66 10.6 3.5 37 5.1 0.0 4.1 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat zf-CCHC PF00098.18 EIE80879.1 - 2.8e-08 33.3 32.4 0.0005 19.8 1.2 4.3 3 1 1 4 4 4 4 Zinc knuckle Sigma70_r1_2 PF00140.15 EIE80879.1 - 0.11 12.2 0.3 0.11 12.2 0.2 2.3 2 0 0 2 2 2 0 Sigma-70 factor, region 1.2 GPI-anchored PF10342.4 EIE80880.1 - 3.2e-08 33.9 3.2 4.1e-08 33.5 2.2 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Bestrophin PF01062.16 EIE80881.1 - 8.6e-58 195.5 0.1 5.1e-35 120.8 0.0 2.2 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel GPI-anchored PF10342.4 EIE80882.1 - 6e-14 52.2 4.1 6e-14 52.2 2.9 1.9 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family RAP1 PF07218.6 EIE80882.1 - 3.6 5.5 13.8 4.3 5.2 9.6 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PAH PF02671.16 EIE80884.1 - 4e-47 157.5 5.4 3.7e-18 64.8 0.6 3.9 4 0 0 4 4 4 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 EIE80884.1 - 4.9e-36 122.5 0.7 2e-35 120.5 0.5 2.1 1 0 0 1 1 1 1 Sin3 family co-repressor Aminotran_1_2 PF00155.16 EIE80885.1 - 2.6e-36 125.3 0.0 1.7e-19 70.0 0.0 2.0 2 0 0 2 2 2 2 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EIE80885.1 - 0.018 13.3 0.0 0.029 12.6 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme WD40 PF00400.27 EIE80887.1 - 9.4e-18 63.3 11.1 3.8e-06 26.5 0.0 4.9 6 0 0 6 6 6 3 WD domain, G-beta repeat eIF2A PF08662.6 EIE80887.1 - 0.012 15.3 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 EIE80887.1 - 0.04 13.6 0.1 0.88 9.3 0.0 2.7 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 EIE80887.1 - 0.057 11.7 0.0 0.21 9.8 0.0 1.7 1 1 1 2 2 2 0 Cytochrome D1 heme domain Pkinase PF00069.20 EIE80888.1 - 6e-63 212.4 0.0 4.9e-39 134.0 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIE80888.1 - 8e-30 103.7 0.0 1.4e-22 80.0 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.19 EIE80888.1 - 8.2e-16 58.0 1.0 2.8e-15 56.2 0.5 2.1 2 0 0 2 2 2 1 Response regulator receiver domain PAS_9 PF13426.1 EIE80888.1 - 6.8e-05 23.1 0.0 0.00033 20.9 0.0 2.3 1 0 0 1 1 1 1 PAS domain Kinase-like PF14531.1 EIE80888.1 - 0.00021 20.3 0.0 0.0017 17.3 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EIE80888.1 - 0.00071 19.3 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family PAS PF00989.19 EIE80888.1 - 0.0022 17.7 0.0 0.0083 15.9 0.0 2.0 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.6 EIE80888.1 - 0.0089 16.1 0.0 0.025 14.6 0.0 1.8 1 0 0 1 1 1 1 PAS fold DUF1206 PF06724.6 EIE80890.1 - 9.2e-24 82.9 17.5 1.2e-10 40.9 1.5 3.2 3 0 0 3 3 3 3 Domain of Unknown Function (DUF1206) DUF2975 PF11188.3 EIE80890.1 - 0.08 12.6 4.0 0.11 12.1 1.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2975) DUF1471 PF07338.8 EIE80890.1 - 0.1 12.2 0.4 0.51 10.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1471) PQQ_2 PF13360.1 EIE80891.1 - 1.1e-18 67.5 0.0 1.1e-13 51.2 0.0 2.2 2 0 0 2 2 2 2 PQQ-like domain PQQ PF01011.16 EIE80891.1 - 1.5e-14 52.7 3.4 6.9e-05 22.1 0.0 4.4 4 0 0 4 4 4 4 PQQ enzyme repeat PQQ_3 PF13570.1 EIE80891.1 - 7.6e-11 41.9 4.2 0.0068 16.6 0.0 5.3 5 1 0 5 5 5 2 PQQ-like domain US22 PF02393.11 EIE80891.1 - 0.099 12.6 0.0 0.31 11.0 0.0 1.7 2 0 0 2 2 2 0 US22 like HMA PF00403.21 EIE80892.1 - 1.5e-54 181.9 0.3 1.5e-12 47.4 0.0 5.9 6 0 0 6 6 6 5 Heavy-metal-associated domain E1-E2_ATPase PF00122.15 EIE80892.1 - 9.2e-53 178.6 1.2 9.2e-53 178.6 0.8 3.0 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EIE80892.1 - 5e-37 128.3 0.0 2.7e-36 126.0 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EIE80892.1 - 7.4e-16 58.8 0.0 3.3e-15 56.7 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EIE80892.1 - 0.00013 21.6 1.0 0.0014 18.2 0.1 2.7 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Tox-PL-2 PF15643.1 EIE80892.1 - 0.00043 20.2 5.3 0.99 9.4 0.0 5.1 5 0 0 5 5 5 2 Papain fold toxin 2 Hairy_orange PF07527.8 EIE80892.1 - 0.045 13.5 0.1 0.21 11.3 0.0 2.2 2 0 0 2 2 2 0 Hairy Orange zinc_ribbon_6 PF14599.1 EIE80892.1 - 8.6 6.2 15.4 0.92 9.3 0.2 4.0 5 0 0 5 5 5 0 Zinc-ribbon DUF4460 PF14687.1 EIE80894.1 - 0.055 13.2 0.1 0.059 13.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4460) HTH_23 PF13384.1 EIE80897.1 - 0.0019 17.7 0.0 0.0025 17.4 0.0 1.2 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Crp_2 PF13545.1 EIE80897.1 - 0.013 15.2 0.0 0.035 13.8 0.0 1.6 1 1 1 2 2 2 0 Crp-like helix-turn-helix domain DUF4031 PF13223.1 EIE80897.1 - 0.032 14.3 0.0 0.034 14.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4031) DDE_3 PF13358.1 EIE80898.1 - 2.2e-08 33.9 0.1 3e-08 33.5 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease PSK_trans_fac PF07704.6 EIE80898.1 - 0.035 14.7 2.7 0.15 12.7 1.6 1.9 1 1 1 2 2 2 0 Rv0623-like transcription factor 2H-phosphodiest PF08975.5 EIE80898.1 - 0.083 12.6 0.1 0.13 12.0 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1868) DUF892 PF05974.7 EIE80898.1 - 0.097 12.4 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF892) DUF4164 PF13747.1 EIE80898.1 - 0.098 12.8 3.2 0.2 11.8 2.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) FliJ PF02050.11 EIE80898.1 - 0.15 12.1 2.5 0.21 11.6 0.8 1.8 2 1 0 2 2 2 0 Flagellar FliJ protein DUF544 PF04424.8 EIE80899.1 - 0.036 13.8 0.1 0.072 12.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF544) DUF2004 PF09406.5 EIE80904.1 - 0.099 12.7 1.2 0.14 12.2 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2004) FANCI_HD2 PF14680.1 EIE80908.1 - 0.015 14.4 0.6 0.028 13.5 0.4 1.4 1 0 0 1 1 1 0 FANCI helical domain 2 DUF3819 PF12842.2 EIE80909.1 - 8.5e-11 41.7 5.6 1.4e-10 41.0 3.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) DDE_3 PF13358.1 EIE80911.1 - 1.5e-07 31.2 0.1 1.9e-07 30.8 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4164 PF13747.1 EIE80911.1 - 0.056 13.5 2.5 0.077 13.1 1.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) PSK_trans_fac PF07704.6 EIE80911.1 - 0.071 13.7 2.7 0.2 12.3 1.8 1.8 1 1 1 2 2 2 0 Rv0623-like transcription factor 2H-phosphodiest PF08975.5 EIE80911.1 - 0.11 12.2 0.1 0.17 11.6 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1868) Retrotrans_gag PF03732.12 EIE80912.1 - 0.0013 18.7 0.0 0.0013 18.7 0.0 3.6 5 1 0 5 5 5 1 Retrotransposon gag protein FlxA PF14282.1 EIE80912.1 - 0.076 12.9 5.4 1.1 9.2 3.8 2.6 1 1 0 1 1 1 0 FlxA-like protein IncA PF04156.9 EIE80912.1 - 0.081 12.5 4.3 0.17 11.4 3.0 1.5 1 0 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 EIE80912.1 - 9.7 3.8 7.7 17 3.0 5.2 1.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DDE_Tnp_IS1595 PF12762.2 EIE80913.1 - 1.7e-05 24.7 0.0 2.5e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 ISXO2-like transposase domain rve PF00665.21 EIE80914.1 - 2.2e-17 63.2 0.0 4.9e-17 62.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE80914.1 - 3.1e-17 62.6 0.2 7.5e-17 61.4 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE80914.1 - 3.3e-09 36.2 0.5 7.3e-09 35.1 0.3 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.1 EIE80914.1 - 2.5e-07 31.1 0.1 6.4e-07 29.7 0.1 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 EIE80914.1 - 8.5e-06 25.6 0.1 6.4e-05 22.8 0.0 2.5 2 0 0 2 2 2 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EIE80914.1 - 0.00022 20.9 0.0 0.00048 19.8 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Tudor-knot PF11717.3 EIE80914.1 - 0.017 14.8 0.1 0.053 13.2 0.1 1.8 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain Asp_protease PF09668.5 EIE80914.1 - 0.019 14.5 0.2 0.16 11.5 0.1 2.2 2 0 0 2 2 2 0 Aspartyl protease AIP3 PF03915.8 EIE80915.1 - 0.0058 15.5 1.7 0.0095 14.8 1.1 1.3 1 0 0 1 1 1 1 Actin interacting protein 3 zf-Sec23_Sec24 PF04810.10 EIE80915.1 - 0.063 12.8 1.5 0.15 11.6 0.1 2.2 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger AHS2 PF02626.10 EIE80915.1 - 0.11 11.7 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Allophanate hydrolase subunit 2 Sgf11 PF08209.6 EIE80915.1 - 0.34 10.2 3.3 1.8 7.9 0.1 2.4 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Docking PF08990.6 EIE80915.1 - 0.6 9.4 3.6 2.9 7.1 0.7 2.5 2 0 0 2 2 2 0 Erythronolide synthase docking RVT_1 PF00078.22 EIE80916.1 - 7.4e-18 64.6 0.0 9.8e-18 64.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_3 PF13358.1 EIE80917.1 - 2.7e-16 59.6 0.1 4.9e-16 58.7 0.0 1.5 2 0 0 2 2 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE80917.1 - 1.9e-12 47.0 0.6 1.9e-12 47.0 0.4 2.7 4 0 0 4 4 2 1 Transposase HTH_29 PF13551.1 EIE80917.1 - 1.2e-06 28.6 0.4 1.2e-06 28.6 0.3 2.0 3 0 0 3 3 1 1 Winged helix-turn helix HTH_38 PF13936.1 EIE80917.1 - 2.4e-06 26.9 0.0 6.3e-06 25.6 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.1 EIE80917.1 - 1.7e-05 24.3 0.0 0.00042 19.8 0.0 2.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.1 EIE80917.1 - 2.5e-05 25.0 3.6 0.02 15.7 0.1 3.7 4 0 0 4 4 3 1 Homeodomain-like domain Sigma70_r4_2 PF08281.7 EIE80917.1 - 0.00013 21.3 3.1 0.0029 17.0 0.0 2.9 3 0 0 3 3 3 1 Sigma-70, region 4 HTH_28 PF13518.1 EIE80917.1 - 0.00015 21.6 0.1 0.00089 19.2 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_21 PF13276.1 EIE80917.1 - 0.00078 19.4 0.0 0.076 13.0 0.0 2.5 2 0 0 2 2 2 1 HTH-like domain LacI PF00356.16 EIE80917.1 - 0.004 16.7 1.1 1.3 8.6 0.1 2.8 3 0 0 3 3 3 1 Bacterial regulatory proteins, lacI family HTH_7 PF02796.10 EIE80917.1 - 0.0044 16.8 1.3 0.048 13.5 0.1 2.7 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase Sigma70_r4 PF04545.11 EIE80917.1 - 0.013 14.8 0.6 0.059 12.6 0.0 2.4 3 0 0 3 3 3 0 Sigma-70, region 4 HTH_Tnp_ISL3 PF13542.1 EIE80917.1 - 0.015 14.4 0.2 5 6.3 0.0 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 UPF0122 PF04297.9 EIE80917.1 - 0.021 14.8 0.0 0.051 13.5 0.0 1.6 1 0 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like HTH_Tnp_4 PF13613.1 EIE80917.1 - 0.026 14.0 0.5 0.06 12.8 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix of DDE superfamily endonuclease CPSase_L_D3 PF02787.14 EIE80917.1 - 0.032 13.9 0.0 0.097 12.4 0.0 1.8 2 0 0 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain DUF2857 PF11198.3 EIE80917.1 - 0.069 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2857) HTH_36 PF13730.1 EIE80917.1 - 0.16 12.1 0.5 4.5 7.4 0.0 3.0 3 0 0 3 3 2 0 Helix-turn-helix domain HTH_17 PF12728.2 EIE80917.1 - 0.38 11.0 3.8 8.2 6.7 0.1 2.8 3 0 0 3 3 2 0 Helix-turn-helix domain DDE_3 PF13358.1 EIE80918.1 - 3.4e-12 46.3 0.3 4.4e-12 45.9 0.2 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE80918.1 - 0.14 12.3 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Integrase core domain Chromo PF00385.19 EIE80919.1 - 5.4e-09 35.5 0.3 5.4e-09 35.5 0.2 2.4 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain DUF2870 PF11069.3 EIE80919.1 - 0.073 13.1 1.6 0.1 12.6 0.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2870) BRE1 PF08647.6 EIE80919.1 - 0.72 9.8 12.2 0.96 9.4 7.2 2.1 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase RVT_1 PF00078.22 EIE80920.1 - 1.5e-11 44.0 0.4 1.2e-10 41.1 0.3 2.2 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP PF00077.15 EIE80920.1 - 0.0003 20.6 0.4 0.0018 18.1 0.1 2.4 1 1 1 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 EIE80920.1 - 0.00098 19.5 0.1 0.0019 18.6 0.1 1.5 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.12 EIE80921.1 - 0.008 16.2 0.5 0.054 13.5 0.0 2.4 2 1 0 3 3 3 1 Retrotransposon gag protein HTH_Tnp_Tc3_2 PF01498.13 EIE80923.1 - 8.7e-06 25.7 2.2 2.1e-05 24.4 1.5 1.7 1 1 0 1 1 1 1 Transposase HTH_Tnp_4 PF13613.1 EIE80923.1 - 0.062 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease Chromo PF00385.19 EIE80924.1 - 3.3e-12 45.8 0.7 7e-12 44.8 0.5 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.21 EIE80925.1 - 6.5e-21 74.6 0.0 1.6e-20 73.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE80925.1 - 5.7e-15 55.2 0.1 1.2e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.12 EIE80925.1 - 7.7e-09 35.5 0.1 2.2e-08 34.0 0.1 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein Chromo PF00385.19 EIE80925.1 - 7.5e-05 22.3 0.0 0.00018 21.1 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 EIE80925.1 - 0.17 11.3 2.7 0.21 11.0 0.8 2.1 1 1 0 1 1 1 0 His(2)-Cys(2) zinc finger Transposase_21 PF02992.9 EIE80926.1 - 1.5e-23 83.0 1.2 2.7e-23 82.2 0.1 1.8 2 0 0 2 2 2 1 Transposase family tnp2 HTH_Tnp_Tc3_2 PF01498.13 EIE80927.1 - 5.2e-11 42.4 0.6 7.1e-11 42.0 0.4 1.2 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.1 EIE80927.1 - 0.0037 17.0 0.0 0.0054 16.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EIE80929.1 - 1.4e-17 63.7 0.0 2.4e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Ku_PK_bind PF08785.6 EIE80929.1 - 0.0022 17.8 0.0 0.0039 17.0 0.0 1.4 1 0 0 1 1 1 1 Ku C terminal domain like rve PF00665.21 EIE80929.1 - 0.01 15.9 0.0 0.014 15.4 0.0 1.3 1 0 0 1 1 1 0 Integrase core domain PAH PF02671.16 EIE80929.1 - 0.084 12.5 0.1 1.5 8.4 0.0 2.4 2 1 0 2 2 2 0 Paired amphipathic helix repeat DUF1018 PF06252.7 EIE80929.1 - 0.087 13.3 0.1 0.26 11.8 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1018) TC1 PF15063.1 EIE80929.1 - 0.12 11.9 0.1 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Thyroid cancer protein 1 DDE_3 PF13358.1 EIE80930.1 - 2.2e-22 79.4 0.1 4.4e-22 78.3 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE80930.1 - 9.4e-15 54.4 0.8 6.6e-14 51.7 0.1 2.6 3 0 0 3 3 3 1 Transposase HTH_29 PF13551.1 EIE80930.1 - 6.1e-05 23.1 0.1 0.00028 21.0 0.0 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_38 PF13936.1 EIE80930.1 - 0.00044 19.7 0.0 0.001 18.5 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_32 PF13565.1 EIE80930.1 - 0.0013 19.4 2.4 0.11 13.3 0.1 3.7 3 1 1 4 4 4 1 Homeodomain-like domain rve PF00665.21 EIE80930.1 - 0.0024 17.9 0.0 0.0065 16.5 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain HTH_23 PF13384.1 EIE80930.1 - 0.0035 16.9 0.0 0.061 12.9 0.0 2.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_21 PF13276.1 EIE80930.1 - 0.0048 16.8 0.1 0.28 11.2 0.0 2.8 3 0 0 3 3 3 1 HTH-like domain HTH_7 PF02796.10 EIE80930.1 - 0.017 14.9 1.1 0.24 11.2 0.0 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain of resolvase HTH_Tnp_4 PF13613.1 EIE80930.1 - 0.022 14.2 0.7 0.041 13.4 0.1 1.7 2 0 0 2 2 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_28 PF13518.1 EIE80930.1 - 0.025 14.5 0.0 0.13 12.3 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain LacI PF00356.16 EIE80930.1 - 0.13 11.9 0.7 1.9 8.1 0.1 2.5 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family CPSase_L_D3 PF02787.14 EIE80930.1 - 0.15 11.8 0.0 0.38 10.5 0.0 1.7 1 0 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain HTH_Tnp_ISL3 PF13542.1 EIE80930.1 - 1.7 7.9 3.8 17 4.6 0.1 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 rve PF00665.21 EIE80931.1 - 9e-26 90.3 0.0 2.2e-25 89.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 EIE80931.1 - 1.4e-05 24.5 0.3 4.5e-05 22.8 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.5 EIE80931.1 - 0.0015 17.9 0.1 0.0044 16.4 0.1 1.8 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger HTH_Tnp_Tc3_2 PF01498.13 EIE80932.1 - 6e-08 32.6 0.6 1.4e-07 31.4 0.4 1.7 1 1 0 1 1 1 1 Transposase DDE_3 PF13358.1 EIE80932.1 - 0.0077 15.9 0.0 0.018 14.7 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE80933.1 - 3.2e-09 36.6 1.7 3e-08 33.5 0.6 2.2 2 0 0 2 2 2 1 Transposase HTH_IclR PF09339.5 EIE80933.1 - 7.6e-05 22.2 0.0 0.00016 21.2 0.0 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_11 PF08279.7 EIE80933.1 - 0.00032 20.2 0.0 0.00071 19.1 0.0 1.5 1 0 0 1 1 1 1 HTH domain HTH_7 PF02796.10 EIE80933.1 - 0.00052 19.8 0.1 0.021 14.6 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_38 PF13936.1 EIE80933.1 - 0.003 17.0 0.0 0.0061 16.0 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.1 EIE80933.1 - 0.004 16.7 0.0 0.0097 15.5 0.0 1.6 2 0 0 2 2 2 1 Homeodomain-like domain HTH_17 PF12728.2 EIE80933.1 - 0.0056 16.9 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain UPF0122 PF04297.9 EIE80933.1 - 0.0059 16.6 0.0 0.01 15.8 0.0 1.3 1 0 0 1 1 1 1 Putative helix-turn-helix protein, YlxM / p13 like HTH_29 PF13551.1 EIE80933.1 - 0.0093 16.1 0.0 0.044 13.9 0.0 1.9 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.1 EIE80933.1 - 0.011 16.5 0.5 7.3 7.4 0.0 2.5 2 1 1 3 3 3 0 Homeodomain-like domain HTH_AsnC-type PF13404.1 EIE80933.1 - 0.012 15.1 0.0 0.022 14.2 0.0 1.4 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_36 PF13730.1 EIE80933.1 - 0.019 15.0 0.0 0.22 11.6 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain MarR_2 PF12802.2 EIE80933.1 - 0.023 14.3 0.0 0.042 13.5 0.0 1.4 1 0 0 1 1 1 0 MarR family HTH_24 PF13412.1 EIE80933.1 - 0.028 13.8 0.0 0.059 12.7 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Sigma70_r4 PF04545.11 EIE80933.1 - 0.031 13.5 0.0 0.057 12.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 Terminase_5 PF06056.7 EIE80933.1 - 0.037 13.5 0.0 0.089 12.3 0.0 1.6 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) GerE PF00196.14 EIE80933.1 - 0.046 13.0 0.0 0.084 12.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family HTH_6 PF01418.12 EIE80933.1 - 0.072 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family Sigma70_r4_2 PF08281.7 EIE80933.1 - 0.077 12.4 0.0 0.2 11.1 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_Tnp_4 PF13613.1 EIE80933.1 - 0.078 12.5 0.1 0.19 11.2 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix of DDE superfamily endonuclease TetR_N PF00440.18 EIE80933.1 - 0.13 11.8 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family HTH_22 PF13309.1 EIE80933.1 - 0.14 11.9 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 HTH domain HTH_40 PF14493.1 EIE80933.1 - 0.15 12.3 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain SYCE1 PF15233.1 EIE80934.1 - 0.0064 16.4 0.3 0.01 15.7 0.2 1.2 1 0 0 1 1 1 1 Synaptonemal complex central element protein 1 TMF_TATA_bd PF12325.3 EIE80934.1 - 0.023 14.4 0.9 0.041 13.6 0.6 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Cluap1 PF10234.4 EIE80934.1 - 0.03 13.5 0.2 0.042 13.0 0.1 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 TBPIP PF07106.8 EIE80934.1 - 0.036 13.6 0.1 0.057 12.9 0.1 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF972 PF06156.8 EIE80934.1 - 0.037 14.3 0.3 0.062 13.6 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF3450 PF11932.3 EIE80934.1 - 0.056 12.7 0.3 0.085 12.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF869 PF05911.6 EIE80934.1 - 0.059 11.6 1.2 0.075 11.2 0.9 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) DUF177 PF02620.12 EIE80934.1 - 0.14 12.2 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized ACR, COG1399 DDE_3 PF13358.1 EIE80935.1 - 3.6e-15 55.9 0.2 7.8e-15 54.9 0.1 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE80935.1 - 5.6e-10 39.1 0.4 1.7e-09 37.6 0.3 1.8 1 0 0 1 1 1 1 Transposase Serglycin PF04360.7 EIE80935.1 - 3.9 7.1 35.7 0.74 9.5 6.9 2.3 1 1 1 2 2 2 0 Serglycin Chromo PF00385.19 EIE80936.1 - 5.1e-09 35.6 3.0 6e-09 35.4 0.1 2.5 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain TcdB_N PF12918.2 EIE80936.1 - 0.11 12.6 0.1 0.11 12.6 0.0 2.4 2 0 0 2 2 2 0 TcdB toxin N-terminal helical domain BRE1 PF08647.6 EIE80936.1 - 4.9 7.1 12.3 6.3 6.8 7.3 2.1 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase FCH PF00611.18 EIE80937.1 - 2.1e-09 37.4 0.2 2.1e-09 37.4 0.1 4.0 4 1 1 5 5 4 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.1 EIE80937.1 - 0.00026 20.5 0.2 0.0006 19.3 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EIE80937.1 - 0.005 16.1 1.2 0.0074 15.6 0.1 1.8 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 EIE80937.1 - 0.035 13.6 0.0 0.11 11.9 0.0 1.9 1 0 0 1 1 1 0 Variant SH3 domain SOBP PF15279.1 EIE80937.1 - 0.86 9.9 37.1 0.094 13.0 22.7 1.6 2 0 0 2 2 2 0 Sine oculis-binding protein Sec5 PF15469.1 EIE80938.1 - 1.1e-51 175.1 6.1 1.1e-51 175.1 4.2 2.5 2 0 0 2 2 2 1 Exocyst complex component Sec5 YEATS PF03366.11 EIE80938.1 - 2.8e-34 116.6 0.9 6.4e-34 115.5 0.6 1.7 1 0 0 1 1 1 1 YEATS family Vps51 PF08700.6 EIE80938.1 - 1.2e-07 31.5 1.4 1.2e-07 31.5 0.9 3.6 3 0 0 3 3 3 1 Vps51/Vps67 Epimerase PF01370.16 EIE80939.1 - 1.6e-70 237.2 0.0 2.1e-70 236.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EIE80939.1 - 1.8e-09 36.9 0.0 2.9e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EIE80939.1 - 5e-05 22.3 0.0 9.1e-05 21.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 EIE80939.1 - 0.00013 21.3 0.0 0.00022 20.5 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EIE80939.1 - 0.0036 17.3 0.0 0.0073 16.3 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EIE80939.1 - 0.0073 16.2 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase_Csub PF13950.1 EIE80939.1 - 0.017 15.0 0.0 0.033 14.1 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose 4-epimerase C-term subunit NAD_binding_4 PF07993.7 EIE80939.1 - 0.036 12.9 0.0 0.06 12.2 0.0 1.5 1 1 0 1 1 1 0 Male sterility protein HMG_box PF00505.14 EIE80940.1 - 1.6e-24 85.9 5.7 1.6e-24 85.9 4.0 2.5 2 1 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EIE80940.1 - 5.2e-13 49.1 4.5 5.2e-13 49.1 3.1 2.4 2 1 0 2 2 2 1 HMG-box domain CHDNT PF08073.7 EIE80940.1 - 0.055 13.1 0.1 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 CHDNT (NUC034) domain RR_TM4-6 PF06459.7 EIE80940.1 - 1.5 8.6 17.5 2.4 8.0 12.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 eIF3_p135 PF12807.2 EIE80940.1 - 1.7 8.5 12.8 0.065 13.1 3.1 2.2 1 1 1 2 2 2 0 Translation initiation factor eIF3 subunit 135 HMG_box_5 PF14887.1 EIE80940.1 - 2.8 7.8 17.2 1.5 8.6 8.8 2.6 1 1 2 3 3 3 0 HMG (high mobility group) box 5 CT47 PF15623.1 EIE80940.1 - 4.7 6.8 17.5 5.7 6.5 12.2 1.1 1 0 0 1 1 1 0 Cancer/testis gene family 47 CRAL_TRIO PF00650.15 EIE80941.1 - 2.3e-33 114.9 0.2 3.7e-33 114.2 0.1 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EIE80941.1 - 7.5e-07 29.1 0.2 7.5e-07 29.1 0.2 2.3 2 1 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EIE80941.1 - 0.00022 21.1 0.1 0.00042 20.2 0.1 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF2294 PF10057.4 EIE80941.1 - 0.57 9.8 3.7 2.1 8.0 0.1 2.7 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2294) Ribonuc_red_sm PF00268.16 EIE80942.1 - 2.2e-118 394.3 4.3 2.7e-118 394.0 3.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain tRNA-synt_1e PF01406.14 EIE80943.1 - 7.9e-133 442.2 5.7 4e-132 439.9 4.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 EIE80943.1 - 3.8e-12 45.5 1.7 3.3e-07 29.3 0.2 3.2 3 0 0 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EIE80943.1 - 2.9e-06 25.5 0.0 3.2e-05 22.1 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1f PF01921.13 EIE80943.1 - 1.9e-05 23.5 0.1 0.0034 16.1 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (K) DALR_2 PF09190.6 EIE80943.1 - 0.0036 17.5 0.1 0.016 15.4 0.1 2.2 1 0 0 1 1 1 1 DALR domain DUF2884 PF11101.3 EIE80943.1 - 0.12 11.7 0.1 0.12 11.7 0.1 3.3 3 1 1 5 5 5 0 Protein of unknown function (DUF2884) Colicin_D PF11429.3 EIE80943.1 - 0.62 10.2 4.2 2.3 8.4 0.0 3.4 3 0 0 3 3 3 0 Colicin D IncA PF04156.9 EIE80945.1 - 0.37 10.3 6.2 0.91 9.0 4.3 1.8 1 1 0 1 1 1 0 IncA protein RCC1 PF00415.13 EIE80946.1 - 2.3e-68 226.2 1.7 2.6e-09 37.1 0.0 7.4 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EIE80946.1 - 8.4e-30 101.7 24.9 4.3e-07 29.3 0.1 8.1 8 1 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat CBM_X PF06204.6 EIE80946.1 - 0.07 12.6 2.0 48 3.5 0.0 4.6 5 0 0 5 5 5 0 Putative carbohydrate binding domain Ofd1_CTDD PF10637.4 EIE80947.1 - 1.9e-78 263.2 0.0 3.3e-72 242.8 0.0 2.1 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 EIE80947.1 - 2.6e-16 59.9 0.0 4.7e-16 59.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MCR_alpha_N PF02745.10 EIE80947.1 - 0.0076 15.4 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 Methyl-coenzyme M reductase alpha subunit, N-terminal domain DNA_repr_REX1B PF14966.1 EIE80948.1 - 1.5e-20 73.3 9.7 3.8e-19 68.8 2.9 2.0 1 1 1 2 2 2 2 DNA repair REX1-B DUF2358 PF10184.4 EIE80948.1 - 3.2e-06 27.0 1.5 6.7e-06 26.0 1.0 1.7 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) DUF1351 PF07083.6 EIE80948.1 - 0.007 16.0 6.1 0.024 14.2 0.7 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF1351) NAAA-beta PF15508.1 EIE80948.1 - 0.0078 16.5 0.7 5 7.5 0.0 2.5 1 1 0 2 2 2 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase DUF3083 PF11281.3 EIE80948.1 - 0.023 13.8 7.0 0.038 13.1 4.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3083) MRP-S27 PF10037.4 EIE80948.1 - 0.043 12.7 6.0 0.05 12.5 4.2 1.0 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 DUF330 PF03886.8 EIE80948.1 - 0.045 13.1 0.1 0.053 12.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF330) DUF3878 PF12994.2 EIE80948.1 - 0.049 12.7 6.3 0.035 13.2 2.4 1.8 1 1 1 2 2 2 0 Domain of unknown function, E. rectale Gene description (DUF3878) DUF4303 PF14136.1 EIE80948.1 - 0.06 12.9 3.3 0.077 12.6 1.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4303) DUF399 PF04187.8 EIE80948.1 - 0.071 12.5 2.2 0.21 11.0 1.5 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF399 Ubiq_cyt_C_chap PF03981.7 EIE80948.1 - 0.11 12.3 0.3 0.18 11.6 0.2 1.4 1 0 0 1 1 1 0 Ubiquinol-cytochrome C chaperone Peptidase_S64 PF08192.6 EIE80948.1 - 0.12 10.7 3.5 0.12 10.6 2.5 1.1 1 0 0 1 1 1 0 Peptidase family S64 Ribosomal_S30AE PF02482.14 EIE80948.1 - 0.14 12.5 4.9 0.16 12.4 2.7 1.6 2 0 0 2 2 1 0 Sigma 54 modulation protein / S30EA ribosomal protein PNK3P PF08645.6 EIE80948.1 - 0.15 11.4 1.2 0.21 10.9 0.8 1.4 1 0 0 1 1 1 0 Polynucleotide kinase 3 phosphatase HisKA_3 PF07730.8 EIE80948.1 - 0.28 11.5 2.7 0.45 10.9 0.4 2.1 1 1 1 2 2 2 0 Histidine kinase DUF2422 PF10337.4 EIE80948.1 - 0.29 9.8 2.4 0.35 9.6 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) Cauli_AT PF03233.8 EIE80948.1 - 0.33 10.6 7.8 0.16 11.6 3.5 1.8 1 1 1 2 2 2 0 Aphid transmission protein DUF2229 PF09989.4 EIE80948.1 - 0.34 10.3 4.4 0.32 10.4 2.4 1.3 1 1 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) DUF445 PF04286.7 EIE80948.1 - 0.48 9.9 9.0 0.58 9.6 6.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Pex19 PF04614.7 EIE80948.1 - 0.58 9.7 10.1 16 4.9 7.0 2.0 1 1 0 1 1 1 0 Pex19 protein family FlgN PF05130.7 EIE80948.1 - 0.7 10.1 8.7 0.25 11.6 2.2 2.1 2 0 0 2 2 2 0 FlgN protein U1snRNP70_N PF12220.3 EIE80948.1 - 0.84 10.0 10.6 0.52 10.6 1.9 2.6 1 1 1 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Tweety PF04906.8 EIE80948.1 - 1.4 7.2 5.8 1.4 7.2 3.4 1.3 1 1 0 1 1 1 0 Tweety V-ATPase_C PF03223.10 EIE80948.1 - 1.5 7.6 7.2 0.69 8.7 3.2 1.7 1 1 0 1 1 1 0 V-ATPase subunit C H-kinase_dim PF02895.9 EIE80948.1 - 1.6 9.1 8.3 15 5.9 5.8 2.7 1 1 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain 7tm_6 PF02949.15 EIE80948.1 - 1.9 7.2 4.5 0.58 8.9 1.1 1.7 2 0 0 2 2 2 0 7tm Odorant receptor CDC37_N PF03234.9 EIE80948.1 - 2 8.7 10.9 3.2 8.0 7.6 1.3 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding V_ATPase_I PF01496.14 EIE80948.1 - 2.2 6.0 8.5 2.4 5.9 5.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Baculo_PEP_C PF04513.7 EIE80948.1 - 3.2 7.5 7.8 4 7.2 3.1 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin-6_N PF09177.6 EIE80948.1 - 3.6 8.0 8.8 58 4.1 5.0 2.6 1 1 0 1 1 1 0 Syntaxin 6, N-terminal DUF2746 PF10874.3 EIE80948.1 - 3.7 7.8 9.0 7.9 6.7 0.5 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2746) IncA PF04156.9 EIE80948.1 - 4.1 6.9 15.8 11 5.5 10.9 1.7 1 1 0 1 1 1 0 IncA protein AAA_11 PF13086.1 EIE80948.1 - 4.7 6.7 8.0 5.6 6.4 5.5 1.2 1 1 0 1 1 1 0 AAA domain TP6A_N PF04406.9 EIE80948.1 - 4.9 6.8 7.2 2.3 7.9 0.3 2.6 3 0 0 3 3 3 0 Type IIB DNA topoisomerase bZIP_1 PF00170.16 EIE80948.1 - 5.2 7.0 10.7 2.9 7.9 0.3 3.0 3 0 0 3 3 3 0 bZIP transcription factor Arch_ATPase PF01637.13 EIE80948.1 - 7.8 6.1 8.9 25 4.4 6.2 1.9 1 1 0 1 1 1 0 Archaeal ATPase ABC_tran PF00005.22 EIE80949.1 - 6.5e-46 156.0 0.3 1.4e-21 77.1 0.0 2.8 3 0 0 3 3 2 2 ABC transporter ABC_tran_2 PF12848.2 EIE80949.1 - 9.7e-19 67.0 6.9 9.7e-19 67.0 4.8 2.7 4 0 0 4 4 1 1 ABC transporter AAA_21 PF13304.1 EIE80949.1 - 2.3e-18 67.1 7.0 0.00071 19.6 0.1 4.3 3 1 1 4 4 4 4 AAA domain SMC_N PF02463.14 EIE80949.1 - 2.2e-10 40.1 0.3 0.02 14.0 0.3 4.4 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EIE80949.1 - 2.3e-08 33.4 4.7 0.00055 19.4 0.0 2.9 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EIE80949.1 - 9.3e-08 32.9 0.2 0.024 15.4 0.0 3.4 2 1 1 3 3 3 2 AAA domain Dynamin_N PF00350.18 EIE80949.1 - 3.3e-07 30.2 0.3 0.0052 16.6 0.0 3.8 2 1 1 3 3 3 1 Dynamin family AAA_23 PF13476.1 EIE80949.1 - 1.1e-06 29.1 6.1 0.039 14.2 0.0 3.6 4 0 0 4 4 3 2 AAA domain AAA_22 PF13401.1 EIE80949.1 - 2.1e-06 27.8 0.1 0.021 14.9 0.0 3.2 2 2 0 2 2 2 2 AAA domain NACHT PF05729.7 EIE80949.1 - 6.4e-06 25.9 0.0 0.021 14.4 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_15 PF13175.1 EIE80949.1 - 8e-06 25.1 1.5 0.65 8.9 0.0 4.3 4 1 0 4 4 4 1 AAA ATPase domain Miro PF08477.8 EIE80949.1 - 8.9e-06 26.1 0.0 0.085 13.3 0.0 3.1 3 0 0 3 3 2 2 Miro-like protein DUF258 PF03193.11 EIE80949.1 - 9.3e-06 24.9 0.0 0.0092 15.1 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 EIE80949.1 - 1.2e-05 25.3 0.1 0.096 12.6 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.1 EIE80949.1 - 2.1e-05 24.4 0.0 0.28 11.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 EIE80949.1 - 9.2e-05 22.2 0.1 0.055 13.4 0.0 2.9 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.18 EIE80949.1 - 0.0001 22.2 0.1 0.72 9.8 0.0 3.4 2 1 0 2 2 2 2 50S ribosome-binding GTPase MobB PF03205.9 EIE80949.1 - 0.00016 21.4 0.0 0.11 12.1 0.0 2.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 EIE80949.1 - 0.00019 21.7 1.1 0.63 10.3 0.0 3.2 3 1 0 3 3 2 2 AAA domain AAA_25 PF13481.1 EIE80949.1 - 0.00031 20.2 0.0 0.9 8.8 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.1 EIE80949.1 - 0.00039 20.3 0.0 1.3 8.9 0.0 3.9 3 1 0 3 3 3 1 AAA domain RNA_helicase PF00910.17 EIE80949.1 - 0.00053 20.1 0.3 1.1 9.4 0.0 3.1 3 0 0 3 3 3 1 RNA helicase AAA_10 PF12846.2 EIE80949.1 - 0.00058 19.3 1.1 0.59 9.5 0.0 3.2 4 0 0 4 4 4 1 AAA-like domain DUF87 PF01935.12 EIE80949.1 - 0.00076 19.3 0.5 1.5 8.5 0.0 3.2 3 0 0 3 3 3 1 Domain of unknown function DUF87 AAA_28 PF13521.1 EIE80949.1 - 0.00085 19.3 0.0 1.2 9.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EIE80949.1 - 0.008 16.3 0.0 1.2 9.3 0.0 3.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DAP3 PF10236.4 EIE80949.1 - 0.0097 14.8 1.9 13 4.5 0.0 3.3 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 FtsK_SpoIIIE PF01580.13 EIE80949.1 - 0.011 15.2 0.0 0.87 9.0 0.0 2.7 3 0 0 3 3 2 0 FtsK/SpoIIIE family PduV-EutP PF10662.4 EIE80949.1 - 0.014 14.8 0.3 2.6 7.5 0.0 3.1 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation ArgK PF03308.11 EIE80949.1 - 0.016 13.9 0.2 3.5 6.3 0.0 2.7 3 0 0 3 3 3 0 ArgK protein T2SE PF00437.15 EIE80949.1 - 0.016 14.0 0.0 0.32 9.8 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_24 PF13479.1 EIE80949.1 - 0.019 14.5 0.6 1.3 8.5 0.0 3.0 3 0 0 3 3 2 0 AAA domain Pox_A32 PF04665.7 EIE80949.1 - 0.02 14.2 0.0 5.6 6.1 0.0 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_30 PF13604.1 EIE80949.1 - 0.023 14.3 0.0 1.2 8.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EIE80949.1 - 0.023 13.5 0.0 6.5 5.5 0.0 2.8 2 1 0 2 2 2 0 NB-ARC domain AAA_5 PF07728.9 EIE80949.1 - 0.024 14.3 0.0 5.4 6.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) SRP54 PF00448.17 EIE80949.1 - 0.026 13.9 0.9 5.1 6.4 0.0 2.9 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain cobW PF02492.14 EIE80949.1 - 0.033 13.6 0.1 6.6 6.1 0.0 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.7 EIE80949.1 - 0.033 13.2 0.0 0.28 10.2 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin Septin PF00735.13 EIE80949.1 - 0.037 13.0 0.0 8.1 5.3 0.0 2.5 2 0 0 2 2 2 0 Septin EIIA-man PF03610.11 EIE80949.1 - 0.04 13.9 1.3 0.14 12.2 0.1 2.2 2 0 0 2 2 2 0 PTS system fructose IIA component DUF948 PF06103.6 EIE80949.1 - 0.062 13.1 0.0 0.21 11.4 0.0 1.9 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) UPF0079 PF02367.12 EIE80949.1 - 0.078 12.6 0.4 3.8 7.1 0.0 3.4 3 1 1 4 4 4 0 Uncharacterised P-loop hydrolase UPF0079 MutS_V PF00488.16 EIE80949.1 - 0.083 12.2 0.0 8.8 5.6 0.0 2.8 3 0 0 3 3 2 0 MutS domain V Lipocalin_5 PF13924.1 EIE80949.1 - 0.12 12.0 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Lipocalin-like domain ATP_bind_1 PF03029.12 EIE80949.1 - 0.22 11.0 2.4 10 5.5 0.1 2.9 3 1 1 4 4 2 0 Conserved hypothetical ATP binding protein AAA_13 PF13166.1 EIE80949.1 - 0.34 9.3 7.9 3.5 5.9 0.4 3.6 3 1 1 4 4 4 0 AAA domain DUF3987 PF13148.1 EIE80949.1 - 1.4 7.4 4.4 3.6 6.0 0.3 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3987) Aconitase PF00330.15 EIE80950.1 - 4e-75 253.0 0.5 4.4e-73 246.3 0.4 3.1 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EIE80950.1 - 2.5e-23 82.6 0.0 4.9e-23 81.6 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.8 EIE80950.1 - 0.016 13.7 0.0 0.026 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) RRM_1 PF00076.17 EIE80951.1 - 3.3e-17 61.8 0.0 6.5e-17 60.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE80951.1 - 7.1e-13 48.3 0.0 1.4e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE80951.1 - 4e-12 45.7 0.0 9.6e-12 44.5 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ParD PF09386.5 EIE80951.1 - 0.0033 17.5 0.3 0.014 15.4 0.0 2.0 2 0 0 2 2 2 1 Antitoxin ParD Involucrin2 PF06994.6 EIE80951.1 - 2.4 8.1 14.5 5.8 6.9 2.0 2.6 2 0 0 2 2 2 0 Involucrin Dynactin_p22 PF07426.6 EIE80952.1 - 0.24 10.6 4.1 0.39 9.9 2.8 1.4 1 0 0 1 1 1 0 Dynactin subunit p22 Carn_acyltransf PF00755.15 EIE80953.1 - 3.5e-189 629.7 0.2 4e-189 629.5 0.1 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Mito_carr PF00153.22 EIE80954.1 - 7e-70 230.8 4.7 4.2e-23 80.8 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein G-gamma PF00631.17 EIE80956.1 - 1.4e-21 75.9 0.0 1.8e-21 75.6 0.0 1.1 1 0 0 1 1 1 1 GGL domain SpoIIP PF07454.6 EIE80956.1 - 0.13 11.3 0.1 0.14 11.2 0.0 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) NDUF_B4 PF07225.7 EIE80957.1 - 0.0048 16.6 0.0 0.0056 16.4 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) C2 PF00168.25 EIE80958.1 - 4.1e-09 36.1 0.6 6.6e-09 35.5 0.0 1.7 2 0 0 2 2 2 1 C2 domain DUF1510 PF07423.6 EIE80958.1 - 1.8e-06 27.4 12.1 2.8e-06 26.8 8.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) CBM_5_12 PF02839.9 EIE80958.1 - 2.1e-06 27.2 1.8 4.1e-06 26.2 1.3 1.5 1 0 0 1 1 1 1 Carbohydrate binding domain IncA PF04156.9 EIE80958.1 - 2.9e-05 23.7 4.0 4.4e-05 23.1 2.8 1.2 1 0 0 1 1 1 1 IncA protein HemX PF04375.9 EIE80958.1 - 0.04 12.5 0.7 0.056 12.0 0.5 1.2 1 0 0 1 1 1 0 HemX Zip PF02535.17 EIE80958.1 - 0.046 12.7 4.5 0.069 12.1 3.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Hid1 PF12722.2 EIE80958.1 - 0.45 8.1 5.8 0.57 7.7 4.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ycf1 PF05758.7 EIE80958.1 - 1 7.0 14.5 1.3 6.6 10.1 1.1 1 0 0 1 1 1 0 Ycf1 MIP-T3 PF10243.4 EIE80958.1 - 2.5 6.4 28.8 3.4 6.0 20.0 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Aconitase PF00330.15 EIE80959.1 - 2.1e-191 636.4 0.0 2.5e-191 636.1 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EIE80959.1 - 4.7e-46 156.1 0.0 9.2e-46 155.1 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain DDE_3 PF13358.1 EIE80960.1 - 1.5e-08 34.5 0.0 2.2e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 EIE80960.1 - 0.0065 15.9 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 helix-turn-helix, Psq domain CENP-B_N PF04218.8 EIE80960.1 - 0.015 14.7 0.1 0.041 13.2 0.0 1.8 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain MTS PF05175.9 EIE80960.1 - 0.023 14.0 0.0 0.033 13.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain HTH_28 PF13518.1 EIE80960.1 - 0.13 12.2 0.0 0.77 9.8 0.0 2.2 3 0 0 3 3 3 0 Helix-turn-helix domain zf-B_box PF00643.19 EIE80962.1 - 0.1 12.5 1.6 0.19 11.6 1.1 1.5 1 0 0 1 1 1 0 B-box zinc finger DUF4448 PF14610.1 EIE80963.1 - 0.00044 19.7 2.0 0.00077 19.0 1.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF2613 PF11021.3 EIE80963.1 - 0.0042 16.7 0.2 0.011 15.4 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2613) DUF912 PF06024.7 EIE80963.1 - 0.011 15.7 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Herpes_gE PF02480.11 EIE80963.1 - 0.025 12.8 0.1 0.033 12.4 0.1 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E MFS_1 PF07690.11 EIE80963.1 - 0.035 12.8 0.0 0.052 12.2 0.0 1.2 1 0 0 1 1 1 0 Major Facilitator Superfamily TMEM154 PF15102.1 EIE80963.1 - 0.079 12.6 0.1 0.16 11.6 0.1 1.5 1 0 0 1 1 1 0 TMEM154 protein family Rifin_STEVOR PF02009.11 EIE80963.1 - 0.13 11.8 0.1 0.27 10.8 0.0 1.6 2 0 0 2 2 2 0 Rifin/stevor family Endosulfine PF04667.12 EIE80964.1 - 1.8e-20 72.7 0.0 2e-20 72.5 0.0 1.2 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Lig_chan PF00060.21 EIE80965.1 - 4.4 7.0 6.8 15 5.2 1.0 2.3 2 0 0 2 2 2 0 Ligand-gated ion channel bZIP_2 PF07716.10 EIE80967.1 - 4.9e-11 42.2 5.6 4.9e-11 42.2 3.9 2.2 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 EIE80967.1 - 3.1e-10 39.8 13.3 6.7e-09 35.5 4.7 2.2 1 1 1 2 2 2 2 bZIP transcription factor bZIP_Maf PF03131.12 EIE80967.1 - 0.0011 19.2 4.9 0.0011 19.2 3.4 2.0 1 1 1 2 2 2 1 bZIP Maf transcription factor Tropomyosin PF00261.15 EIE80967.1 - 0.0023 17.0 6.8 0.0032 16.5 4.7 1.2 1 0 0 1 1 1 1 Tropomyosin HAP1_N PF04849.8 EIE80967.1 - 0.011 14.6 7.4 0.017 14.1 5.1 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region Striatin PF08232.7 EIE80967.1 - 0.014 15.7 3.1 0.014 15.7 2.1 1.9 1 1 1 2 2 2 0 Striatin family DivIC PF04977.10 EIE80967.1 - 0.015 14.7 1.9 0.03 13.8 1.3 1.4 1 0 0 1 1 1 0 Septum formation initiator ADIP PF11559.3 EIE80967.1 - 0.03 14.2 7.3 0.047 13.6 5.1 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Spc7 PF08317.6 EIE80967.1 - 0.065 11.8 3.4 0.088 11.4 2.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein CtIP_N PF10482.4 EIE80967.1 - 0.11 12.2 4.9 0.12 12.1 2.5 1.6 1 1 1 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain IncA PF04156.9 EIE80967.1 - 0.11 12.0 4.3 0.16 11.5 3.0 1.2 1 0 0 1 1 1 0 IncA protein Prefoldin_2 PF01920.15 EIE80967.1 - 0.17 11.6 5.6 2.9 7.6 0.3 2.3 1 1 1 2 2 2 0 Prefoldin subunit IFP_35_N PF07334.8 EIE80967.1 - 0.51 10.3 3.1 6.6 6.7 0.4 2.6 1 1 1 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus APG6 PF04111.7 EIE80967.1 - 1 8.3 7.0 1.3 8.0 4.9 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 BRI3BP PF14965.1 EIE80967.1 - 1.1 8.6 2.8 6.7 6.0 0.1 2.1 2 0 0 2 2 2 0 Negative regulator of p53/TP53 V_ATPase_I PF01496.14 EIE80967.1 - 1.2 6.9 4.0 1.5 6.5 2.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Sugarporin_N PF11471.3 EIE80967.1 - 1.7 8.3 8.5 0.47 10.1 2.1 2.3 1 1 0 2 2 2 0 Maltoporin periplasmic N-terminal extension PspB PF06667.7 EIE80967.1 - 2.6 8.0 4.4 22 5.0 0.2 2.4 1 1 1 2 2 2 0 Phage shock protein B M PF02370.11 EIE80967.1 - 5.8 7.6 6.0 24 5.7 0.2 3.4 2 1 1 3 3 3 0 M protein repeat Methyltransf_23 PF13489.1 EIE80968.1 - 1.7e-14 53.8 0.0 3.3e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIE80968.1 - 2.9e-12 46.9 0.0 7.4e-12 45.5 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIE80968.1 - 2.2e-10 40.3 0.0 1e-05 25.1 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.1 EIE80968.1 - 1.3e-09 38.3 0.0 4.2e-09 36.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIE80968.1 - 4.9e-08 33.5 0.0 2e-07 31.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIE80968.1 - 5.1e-06 26.8 0.0 1.2e-05 25.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EIE80968.1 - 6.7e-06 25.2 0.0 1.8e-05 23.9 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase CheR PF01739.13 EIE80968.1 - 3.4e-05 23.2 0.0 0.00031 20.0 0.0 2.0 2 0 0 2 2 2 1 CheR methyltransferase, SAM binding domain FtsJ PF01728.14 EIE80968.1 - 0.00051 20.0 0.0 0.0013 18.7 0.0 1.7 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 EIE80968.1 - 0.00068 19.6 0.0 0.0016 18.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 EIE80968.1 - 0.0036 16.5 0.0 0.025 13.7 0.0 2.0 1 1 0 1 1 1 1 Tellurite resistance protein TehB MTS PF05175.9 EIE80968.1 - 0.0036 16.6 0.0 0.0052 16.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 EIE80968.1 - 0.004 16.3 0.0 0.042 12.9 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.6 EIE80968.1 - 0.026 13.2 0.0 0.034 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) DUF938 PF06080.7 EIE80968.1 - 0.056 12.9 0.0 0.14 11.6 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_2 PF00891.13 EIE80968.1 - 0.09 11.9 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase CMAS PF02353.15 EIE80968.1 - 0.14 11.1 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_29 PF03141.11 EIE80968.1 - 0.15 10.3 0.0 3.8 5.7 0.0 2.1 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase WD40 PF00400.27 EIE80971.1 - 3.2e-41 137.7 7.0 7.2e-13 47.8 0.4 3.6 3 1 0 3 3 3 3 WD domain, G-beta repeat eIF2A PF08662.6 EIE80971.1 - 0.007 16.0 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A NHL PF01436.16 EIE80971.1 - 0.018 14.9 0.0 3.4 7.7 0.0 2.3 2 0 0 2 2 2 0 NHL repeat LisH PF08513.6 EIE80971.1 - 0.036 13.8 0.1 0.071 12.9 0.0 1.5 1 0 0 1 1 1 0 LisH Transketolase_N PF00456.16 EIE80972.1 - 1.3e-152 507.4 0.0 2e-152 506.7 0.0 1.3 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 EIE80972.1 - 1.3e-42 145.3 0.0 2.4e-42 144.4 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EIE80972.1 - 2.4e-08 33.9 0.0 8.2e-08 32.2 0.0 1.9 2 0 0 2 2 2 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 EIE80972.1 - 6e-06 25.3 0.0 1.4e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase IF2_N PF04760.10 EIE80972.1 - 0.096 12.3 0.5 1 9.0 0.0 2.8 3 0 0 3 3 3 0 Translation initiation factor IF-2, N-terminal region Scm3 PF10384.4 EIE80972.1 - 0.11 12.0 0.8 0.24 10.9 0.5 1.6 1 0 0 1 1 1 0 Centromere protein Scm3 Phage_DsbA PF11126.3 EIE80972.1 - 0.15 12.1 3.1 0.3 11.1 2.2 1.5 1 0 0 1 1 1 0 Transcriptional regulator DsbA Pkinase PF00069.20 EIE80973.1 - 1.5e-41 142.2 0.1 4e-20 72.0 0.0 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIE80973.1 - 8.8e-19 67.5 0.0 1.5e-10 40.5 0.1 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EIE80973.1 - 0.0023 16.9 0.0 0.0048 15.9 0.0 1.4 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EIE80973.1 - 0.013 15.2 0.3 0.044 13.5 0.1 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family RmlD_sub_bind PF04321.12 EIE80974.1 - 0.04 12.8 0.5 0.054 12.3 0.1 1.4 1 1 1 2 2 2 0 RmlD substrate binding domain bHLH-MYC_N PF14215.1 EIE80974.1 - 0.079 13.1 0.3 0.11 12.7 0.2 1.3 1 1 0 1 1 1 0 bHLH-MYC and R2R3-MYB transcription factors N-terminal HEAT PF02985.17 EIE80975.1 - 4.8e-41 135.1 25.7 0.0029 17.5 0.0 13.0 13 0 0 13 13 13 11 HEAT repeat HEAT_2 PF13646.1 EIE80975.1 - 1.5e-28 98.8 11.2 9.2e-07 29.0 0.0 6.3 4 1 2 6 6 6 6 HEAT repeats Vac14_Fab1_bd PF12755.2 EIE80975.1 - 3.8e-08 33.6 0.8 0.86 10.0 0.0 5.9 2 1 4 7 7 7 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 EIE80975.1 - 4.7e-08 33.2 11.7 0.0033 17.8 0.1 9.4 7 3 5 12 12 12 2 HEAT-like repeat DUF2435 PF10363.4 EIE80975.1 - 0.0015 18.3 2.7 2.6 8.0 0.0 4.3 4 1 1 5 5 5 1 Protein of unknown function (DUF2435) Arm PF00514.18 EIE80975.1 - 0.0033 17.2 3.8 34 4.4 0.0 6.5 6 1 1 7 7 7 0 Armadillo/beta-catenin-like repeat Cnd1 PF12717.2 EIE80975.1 - 0.0034 17.2 4.0 0.75 9.6 0.1 4.6 2 2 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 DNA_alkylation PF08713.6 EIE80975.1 - 0.012 15.0 0.5 1.3 8.4 0.0 3.1 2 2 1 3 3 3 0 DNA alkylation repair enzyme RasGAP PF00616.14 EIE80976.1 - 9.3e-42 142.9 0.3 9.3e-42 142.9 0.2 2.3 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 EIE80976.1 - 2.5e-33 114.7 4.2 2.5e-33 114.7 2.9 2.9 3 0 0 3 3 3 1 RasGAP C-terminus IQ PF00612.22 EIE80976.1 - 0.014 15.0 6.5 0.27 10.9 1.0 3.3 3 0 0 3 3 3 0 IQ calmodulin-binding motif Pkinase PF00069.20 EIE80977.1 - 1.7e-54 184.7 0.1 2.1e-54 184.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE80977.1 - 2.7e-25 88.9 0.0 3.7e-25 88.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EIE80977.1 - 0.043 12.8 0.0 0.096 11.7 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIE80977.1 - 0.048 13.3 0.1 0.17 11.6 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family VitK2_biosynth PF02621.9 EIE80977.1 - 0.069 12.3 0.0 0.099 11.8 0.0 1.2 1 0 0 1 1 1 0 Menaquinone biosynthesis zf-Nse PF11789.3 EIE80977.1 - 0.096 12.2 0.1 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Sel1 PF08238.7 EIE80978.1 - 4.3e-48 160.6 24.7 3.3e-08 33.9 0.0 7.4 7 0 0 7 7 7 7 Sel1 repeat TPR_11 PF13414.1 EIE80978.1 - 0.027 14.1 4.4 0.47 10.1 0.1 4.1 2 1 2 4 4 4 0 TPR repeat TPR_6 PF13174.1 EIE80978.1 - 1.5 9.4 9.9 13 6.5 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF2052 PF09747.4 EIE80980.1 - 6.4e-31 107.6 31.5 2.6e-30 105.7 22.5 1.5 2 0 0 2 2 2 1 Coiled-coil domain containing protein (DUF2052) HSF_DNA-bind PF00447.12 EIE80982.1 - 4.5e-08 33.2 0.9 4.5e-08 33.2 0.6 1.9 2 0 0 2 2 2 1 HSF-type DNA-binding Lzipper-MIP1 PF14389.1 EIE80982.1 - 0.018 15.1 2.1 0.038 14.1 1.4 1.5 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 Cortex-I_coil PF09304.5 EIE80982.1 - 0.074 13.1 4.8 0.12 12.3 3.3 1.3 1 0 0 1 1 1 0 Cortexillin I, coiled coil DUF972 PF06156.8 EIE80982.1 - 0.41 11.0 6.2 1 9.7 2.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Ribosomal_S14 PF00253.16 EIE80983.1 - 4.5e-21 73.9 0.1 1.1e-20 72.7 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e Lung_7-TM_R PF06814.8 EIE80985.1 - 3.3e-60 203.5 22.9 4.1e-60 203.2 15.9 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor zf-C2H2 PF00096.21 EIE80986.1 - 3.3e-09 36.5 8.0 0.00025 21.2 0.5 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIE80986.1 - 4.6e-09 36.1 18.4 3.5e-07 30.1 0.4 4.2 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 EIE80986.1 - 0.0067 16.6 13.5 0.016 15.4 0.3 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-BED PF02892.10 EIE80986.1 - 0.12 12.1 6.5 2.3 8.0 1.1 2.4 2 0 0 2 2 2 0 BED zinc finger zf-met PF12874.2 EIE80986.1 - 0.14 12.4 0.2 0.14 12.4 0.2 2.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.1 EIE80986.1 - 0.28 11.4 3.6 15 6.0 0.1 3.3 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.1 EIE80986.1 - 0.86 9.5 4.9 9.9 6.2 0.2 3.2 2 0 0 2 2 2 0 C2H2-type zinc finger Zn_Tnp_IS1595 PF12760.2 EIE80986.1 - 3.2 7.6 5.5 16 5.3 0.4 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain GCR1_C PF12550.3 EIE80987.1 - 5.1e-26 90.3 0.7 5.1e-25 87.1 0.2 2.6 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes Pkinase PF00069.20 EIE80988.1 - 6.3e-71 238.5 0.0 8.3e-71 238.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE80988.1 - 9.7e-32 110.0 0.0 2.7e-31 108.5 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EIE80988.1 - 0.008 15.9 0.4 0.022 14.4 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EIE80988.1 - 0.013 14.5 0.0 0.023 13.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EIE80988.1 - 0.065 12.1 0.0 0.22 10.4 0.0 1.9 2 0 0 2 2 2 0 Kinase-like HLH PF00010.21 EIE80989.1 - 1.5e-17 63.0 0.6 1.5e-17 63.0 0.4 2.2 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Glyco_transf_49 PF13896.1 EIE80991.1 - 5.8e-38 130.7 3.6 1.8e-29 102.8 1.1 2.1 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glyco_tranf_2_2 PF10111.4 EIE80991.1 - 0.00065 18.8 0.4 0.0037 16.3 0.1 2.2 2 1 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.1 EIE80991.1 - 0.032 14.5 1.3 0.086 13.1 0.1 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 2 SAM_decarbox PF01536.11 EIE80992.1 - 6.3e-100 334.0 0.8 9.4e-59 198.7 0.0 2.7 2 1 0 2 2 2 2 Adenosylmethionine decarboxylase WD40 PF00400.27 EIE80993.1 - 1.2e-24 85.2 14.6 2.2e-07 30.4 0.4 7.5 7 1 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 EIE80993.1 - 0.00066 17.9 1.1 0.01 14.0 0.2 2.6 2 1 1 4 4 4 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EIE80993.1 - 0.00069 18.4 0.7 0.13 10.9 0.0 2.7 2 1 1 3 3 3 2 Nup133 N terminal like Hira PF07569.6 EIE80993.1 - 0.0029 16.8 0.1 1.4 8.1 0.0 3.4 3 0 0 3 3 3 1 TUP1-like enhancer of split Nbas_N PF15492.1 EIE80993.1 - 0.003 16.6 0.3 1.2 8.1 0.0 2.9 2 1 0 2 2 2 2 Neuroblastoma-amplified sequence, N terminal PQQ_2 PF13360.1 EIE80993.1 - 0.084 12.3 0.1 12 5.2 0.0 3.2 2 2 0 2 2 2 0 PQQ-like domain Pkinase PF00069.20 EIE80994.1 - 1.8e-68 230.5 0.0 1e-67 228.0 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE80994.1 - 5.6e-38 130.5 0.0 2.3e-37 128.4 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase KA1 PF02149.14 EIE80994.1 - 2.3e-06 26.9 0.1 4.6e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 APH PF01636.18 EIE80994.1 - 4e-06 26.7 0.0 0.021 14.5 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EIE80994.1 - 4.1e-06 25.9 0.0 6.6e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EIE80994.1 - 0.00011 21.3 0.0 0.00019 20.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EIE80994.1 - 0.028 13.7 0.0 0.072 12.4 0.0 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL EcKinase PF02958.15 EIE80994.1 - 0.053 12.6 0.5 0.36 9.9 0.0 2.1 2 0 0 2 2 2 0 Ecdysteroid kinase Myosin_head PF00063.16 EIE80995.1 - 1.1e-248 826.7 3.3 1.1e-248 826.7 2.3 2.2 2 0 0 2 2 2 1 Myosin head (motor domain) DIL PF01843.14 EIE80995.1 - 1.2e-31 108.7 1.8 1.2e-31 108.7 1.3 2.3 2 0 0 2 2 2 1 DIL domain IQ PF00612.22 EIE80995.1 - 5.2e-13 47.3 40.8 2.3e-05 23.6 1.2 7.1 7 0 0 7 7 7 5 IQ calmodulin-binding motif AAA_22 PF13401.1 EIE80995.1 - 0.015 15.4 2.8 0.041 14.0 0.0 3.1 2 1 1 3 3 3 0 AAA domain Pox_A_type_inc PF04508.7 EIE80995.1 - 0.032 14.0 0.4 6 6.9 0.0 3.6 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat AAA_19 PF13245.1 EIE80995.1 - 0.054 13.2 0.0 0.19 11.4 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain AAA_16 PF13191.1 EIE80995.1 - 0.27 11.2 4.4 0.39 10.6 0.0 3.2 3 1 0 3 3 3 0 AAA ATPase domain Pkinase PF00069.20 EIE81001.1 - 7.1e-55 185.9 0.2 9.4e-55 185.5 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE81001.1 - 9.8e-28 96.9 0.1 2e-27 95.9 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE81001.1 - 0.00017 20.6 0.0 0.00028 19.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EIE81001.1 - 0.00028 20.2 1.0 0.00053 19.3 0.7 1.5 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 EIE81001.1 - 0.0013 17.8 0.2 0.0022 17.0 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIE81001.1 - 0.038 13.7 0.0 0.29 10.8 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family ATP-synt_ab PF00006.20 EIE81002.1 - 1.3e-69 234.0 0.0 2.1e-69 233.3 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EIE81002.1 - 7.1e-26 90.9 0.0 1.8e-25 89.5 0.0 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EIE81002.1 - 1.9e-20 72.8 0.6 1.9e-20 72.8 0.4 1.9 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EIE81002.1 - 2.7e-05 23.9 0.3 0.00011 22.0 0.2 2.0 1 1 0 1 1 1 1 HAS barrel domain Cid2 PF09774.4 EIE81003.1 - 0.027 14.5 0.0 0.027 14.5 0.0 1.1 1 0 0 1 1 1 0 Caffeine-induced death protein 2 JAB PF01398.16 EIE81004.1 - 9.4e-11 41.4 0.0 3.3e-10 39.7 0.0 1.9 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Aa_trans PF01490.13 EIE81005.1 - 7.5e-63 212.4 29.0 7.5e-63 212.4 20.1 1.6 2 0 0 2 2 2 1 Transmembrane amino acid transporter protein MutS_III PF05192.13 EIE81008.1 - 0.025 14.3 12.9 0.57 9.9 2.9 2.2 1 1 1 2 2 2 0 MutS domain III Utp12 PF04003.7 EIE81008.1 - 0.035 14.0 5.8 4.3 7.2 0.2 3.7 2 1 1 3 3 3 0 Dip2/Utp12 Family DUF3499 PF12005.3 EIE81008.1 - 0.46 10.6 4.9 1.5 9.0 0.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3499) VPS9 PF02204.13 EIE81008.1 - 3.4 7.7 10.0 12 6.0 1.6 3.2 3 1 0 3 3 3 0 Vacuolar sorting protein 9 (VPS9) domain DUF627 PF04781.7 EIE81008.1 - 3.6 7.2 11.0 0.19 11.3 1.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF627) RGS PF00615.14 EIE81008.1 - 3.7 7.6 21.3 1 9.4 5.0 3.3 1 1 2 3 3 3 0 Regulator of G protein signaling domain DUF2252 PF10009.4 EIE81008.1 - 4.8 5.9 10.8 1.7 7.4 4.4 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2252) Hid1 PF12722.2 EIE81009.1 - 0.0025 15.5 28.3 0.003 15.3 19.6 1.3 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein CENP-T PF15511.1 EIE81009.1 - 0.021 14.1 28.0 0.028 13.7 19.4 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Ndc1_Nup PF09531.5 EIE81009.1 - 4.7 5.5 14.7 6.1 5.1 10.2 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Bap31 PF05529.7 EIE81010.1 - 0.12 11.8 1.6 0.16 11.3 1.1 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Seryl_tRNA_N PF02403.17 EIE81010.1 - 0.24 11.4 3.9 0.32 11.0 2.2 1.5 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain AMP-binding PF00501.23 EIE81011.1 - 4.4e-91 305.3 0.0 5.6e-91 305.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EIE81011.1 - 9.9e-12 45.6 0.1 2.2e-11 44.5 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain TPT PF03151.11 EIE81012.1 - 7.9e-15 54.8 3.8 7.9e-15 54.8 2.6 2.8 1 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EIE81012.1 - 1.4e-12 47.2 20.7 1.5e-12 47.0 14.4 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 EIE81012.1 - 0.00011 22.2 5.4 0.00011 22.2 3.7 2.3 2 0 0 2 2 2 1 EamA-like transporter family Nuc_sug_transp PF04142.10 EIE81012.1 - 0.00071 18.7 2.9 0.0012 18.0 2.0 1.4 1 0 0 1 1 1 1 Nucleotide-sugar transporter PHO4 PF01384.15 EIE81012.1 - 0.042 12.5 10.3 0.028 13.0 2.0 2.3 2 0 0 2 2 2 0 Phosphate transporter family Multi_Drug_Res PF00893.14 EIE81012.1 - 1.9 9.0 20.1 0.098 13.1 4.3 3.1 3 0 0 3 3 3 0 Small Multidrug Resistance protein SNO PF01174.14 EIE81013.1 - 4.4e-55 186.2 0.1 5e-55 186.0 0.0 1.0 1 0 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.9 EIE81013.1 - 1.6e-10 40.7 0.1 2.4e-10 40.2 0.0 1.5 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.23 EIE81013.1 - 5.1e-07 29.3 0.2 1.1e-06 28.2 0.1 1.5 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_S51 PF03575.12 EIE81013.1 - 0.00016 21.4 0.0 0.00023 20.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S51 DJ-1_PfpI PF01965.19 EIE81013.1 - 0.00026 20.4 0.0 0.00043 19.7 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 EIE81013.1 - 0.01 15.1 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 0 Putative amidotransferase DEAD PF00270.24 EIE81014.1 - 7e-44 149.2 0.5 1.4e-43 148.2 0.1 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIE81014.1 - 2.4e-29 101.0 0.1 5.4e-29 99.8 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EIE81014.1 - 0.0022 18.1 0.1 0.0064 16.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EIE81014.1 - 0.016 14.9 1.0 0.035 13.8 0.2 1.9 2 0 0 2 2 2 0 Part of AAA domain ResIII PF04851.10 EIE81014.1 - 0.033 14.0 0.0 0.16 11.8 0.0 2.0 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_30 PF13604.1 EIE81014.1 - 0.044 13.3 0.1 0.13 11.8 0.1 1.8 1 1 0 1 1 1 0 AAA domain Helicase_C_2 PF13307.1 EIE81014.1 - 0.049 13.5 0.0 0.087 12.7 0.0 1.4 1 0 0 1 1 1 0 Helicase C-terminal domain PhoH PF02562.11 EIE81014.1 - 0.08 12.1 0.6 0.37 9.9 0.1 2.0 2 0 0 2 2 2 0 PhoH-like protein CMS1 PF14617.1 EIE81014.1 - 0.098 11.7 0.1 0.46 9.5 0.0 2.0 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Ribosomal_L14 PF00238.14 EIE81015.1 - 1.4e-34 118.4 0.0 1.6e-34 118.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e PALP PF00291.20 EIE81016.1 - 1.5e-67 228.0 0.2 1.8e-67 227.7 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Rpr2 PF04032.11 EIE81017.1 - 5e-06 26.2 3.2 7e-06 25.8 2.2 1.2 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain DUF1660 PF07874.6 EIE81017.1 - 0.36 11.1 0.2 0.36 11.1 0.1 2.0 1 1 1 2 2 2 0 Prophage protein (DUF1660) A_deaminase PF00962.17 EIE81018.1 - 0.00062 18.7 0.0 0.0014 17.5 0.0 1.5 1 0 0 1 1 1 1 Adenosine/AMP deaminase VRP3 PF03536.10 EIE81021.1 - 0.0039 16.3 0.3 0.004 16.3 0.2 1.0 1 0 0 1 1 1 1 Salmonella virulence-associated 28kDa protein Sec8_exocyst PF04048.9 EIE81021.1 - 0.064 12.8 0.3 0.26 10.9 0.2 1.7 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain SATase_N PF06426.9 EIE81021.1 - 0.065 13.4 0.1 0.099 12.9 0.1 1.4 1 1 0 1 1 1 0 Serine acetyltransferase, N-terminal MIF PF01187.13 EIE81021.1 - 0.081 13.0 0.1 0.091 12.8 0.0 1.2 1 0 0 1 1 1 0 Macrophage migration inhibitory factor (MIF) Sugar_tr PF00083.19 EIE81022.1 - 2.5e-119 398.8 20.4 2.8e-119 398.6 14.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIE81022.1 - 3.8e-23 81.7 52.8 1.3e-20 73.3 20.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Topo_Zn_Ribbon PF08272.6 EIE81022.1 - 0.063 12.6 0.1 0.15 11.4 0.1 1.6 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like PC_rep PF01851.17 EIE81023.1 - 3e-29 99.5 22.1 1.8e-06 27.8 0.2 9.0 9 0 0 9 9 9 7 Proteasome/cyclosome repeat Ribosomal_L16 PF00252.13 EIE81024.1 - 1e-33 115.8 0.1 1.3e-33 115.6 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Peroxin-13_N PF04088.8 EIE81025.1 - 1.9e-38 131.9 0.2 2.5e-38 131.5 0.1 1.1 1 0 0 1 1 1 1 Peroxin 13, N-terminal region RRM_1 PF00076.17 EIE81026.1 - 1.6e-26 91.7 0.0 2.8e-14 52.4 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PUF PF00806.14 EIE81026.1 - 1.3e-23 81.1 1.5 4.3e-05 22.7 0.2 6.7 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_6 PF14259.1 EIE81026.1 - 1.8e-21 75.9 0.0 1.7e-10 40.6 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE81026.1 - 2.9e-18 65.4 0.1 7.4e-08 32.1 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EIE81026.1 - 9.2e-05 22.2 0.0 0.27 11.1 0.0 2.6 2 0 0 2 2 2 2 RNA binding motif Limkain-b1 PF11608.3 EIE81026.1 - 0.0017 18.0 0.1 0.027 14.2 0.0 2.4 2 0 0 2 2 2 1 Limkain b1 Pkinase PF00069.20 EIE81027.1 - 1.8e-30 105.9 1.4 8.2e-19 67.7 0.1 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIE81027.1 - 1.1e-13 50.8 0.1 3.8e-08 32.7 0.0 2.0 1 1 1 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EIE81027.1 - 1.1e-05 25.2 0.0 1.5e-05 24.8 0.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EIE81027.1 - 0.0004 19.3 0.1 0.00048 19.0 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.9 EIE81027.1 - 0.00056 19.0 0.4 0.00096 18.2 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EIE81027.1 - 0.00072 18.6 0.0 0.00086 18.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.15 EIE81027.1 - 0.0037 16.8 0.1 0.0039 16.7 0.1 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 EIE81027.1 - 0.01 15.1 0.3 0.018 14.3 0.2 1.4 1 1 0 1 1 1 0 RIO1 family Pox_ser-thr_kin PF05445.6 EIE81027.1 - 0.011 14.5 0.4 0.025 13.3 0.1 1.4 1 1 0 1 1 1 0 Poxvirus serine/threonine protein kinase WaaY PF06176.6 EIE81027.1 - 0.021 14.0 0.5 0.031 13.4 0.3 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) EcKinase PF02958.15 EIE81027.1 - 0.029 13.5 0.0 0.037 13.1 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Abhydrolase_1 PF00561.15 EIE81029.1 - 5.3e-42 143.9 0.0 9.3e-42 143.1 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EIE81029.1 - 9.4e-13 48.5 0.0 1.7e-12 47.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIE81029.1 - 0.0047 16.6 0.0 0.058 13.1 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S8 PF00082.17 EIE81030.1 - 4.3e-48 163.8 1.7 6.7e-48 163.2 1.2 1.3 1 0 0 1 1 1 1 Subtilase family PA PF02225.17 EIE81030.1 - 3.3e-16 58.8 0.0 9.1e-16 57.4 0.0 1.8 1 0 0 1 1 1 1 PA domain DUF1034 PF06280.7 EIE81030.1 - 2.5e-14 53.6 0.1 5.1e-14 52.6 0.1 1.6 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) DoxA PF07680.6 EIE81030.1 - 0.067 12.8 0.0 0.26 10.9 0.0 2.0 2 0 0 2 2 2 0 TQO small subunit DoxA Rhodanese PF00581.15 EIE81031.1 - 1.8e-14 54.0 0.0 2.7e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain GATA PF00320.22 EIE81032.1 - 5.8e-32 108.7 12.7 2.1e-17 62.1 1.8 2.5 2 0 0 2 2 2 2 GATA zinc finger DUF1752 PF08550.5 EIE81032.1 - 3.8e-07 29.5 0.7 8.5e-07 28.4 0.5 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) RRN7 PF11781.3 EIE81032.1 - 0.0061 16.0 3.4 0.61 9.6 0.0 2.9 2 1 0 2 2 2 2 RNA polymerase I-specific transcription initiation factor Rrn7 Zn-ribbon_8 PF09723.5 EIE81032.1 - 0.056 13.4 3.1 6.6 6.7 0.3 2.8 2 1 0 2 2 2 0 Zinc ribbon domain DZR PF12773.2 EIE81032.1 - 0.093 12.5 7.8 4.4 7.2 5.5 2.7 1 1 1 2 2 2 0 Double zinc ribbon TF_Zn_Ribbon PF08271.7 EIE81032.1 - 0.096 12.0 6.0 1.8 7.9 0.6 2.6 2 1 0 2 2 2 0 TFIIB zinc-binding eIF-5_eIF-2B PF01873.12 EIE81032.1 - 0.16 11.6 3.7 3.6 7.2 0.1 2.4 2 0 0 2 2 2 0 Domain found in IF2B/IF5 FYVE PF01363.16 EIE81032.1 - 0.49 10.3 4.1 2.2 8.2 2.8 2.2 1 1 0 1 1 1 0 FYVE zinc finger zf-ribbon_3 PF13248.1 EIE81032.1 - 0.55 9.5 10.8 1.3 8.3 0.3 2.9 2 1 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.2 EIE81032.1 - 1.5 8.6 8.0 0.46 10.3 0.2 2.8 2 1 1 3 3 3 0 Transposase zinc-ribbon domain Sugar_tr PF00083.19 EIE81033.1 - 4.7e-115 384.7 19.3 5.3e-115 384.5 13.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIE81033.1 - 6.7e-20 71.0 52.1 4.5e-18 65.0 17.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF441 PF04284.8 EIE81033.1 - 0.0011 18.9 0.3 0.0033 17.3 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF441) 3Beta_HSD PF01073.14 EIE81035.1 - 8.8e-70 234.5 0.0 1.1e-69 234.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EIE81035.1 - 1e-30 106.9 0.0 1.3e-30 106.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIE81035.1 - 5.5e-15 55.8 0.0 7.4e-15 55.4 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 EIE81035.1 - 3.9e-14 52.2 0.0 4.8e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 EIE81035.1 - 1.6e-13 50.1 0.0 1.2e-12 47.3 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 EIE81035.1 - 8.9e-08 31.3 0.0 3.8e-07 29.3 0.0 2.0 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.5 EIE81035.1 - 0.0015 18.2 0.0 0.068 12.8 0.0 2.3 1 1 0 1 1 1 1 KR domain adh_short PF00106.20 EIE81035.1 - 0.029 14.3 0.1 0.45 10.4 0.1 2.3 1 1 0 1 1 1 0 short chain dehydrogenase Metallophos PF00149.23 EIE81037.1 - 7.1e-13 48.4 4.6 1.2e-12 47.6 3.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase MFS_1 PF07690.11 EIE81038.1 - 5.2e-15 55.0 21.3 5.2e-15 55.0 14.8 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF347 PF03988.7 EIE81038.1 - 1.7 8.5 6.5 6.2 6.7 0.1 4.2 4 0 0 4 4 4 0 Repeat of Unknown Function (DUF347) DUF983 PF06170.7 EIE81038.1 - 3.8 7.6 10.0 4.3 7.5 0.3 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF983) DNA_pol_A_exo1 PF01612.15 EIE81039.1 - 1.3e-22 80.1 0.0 2e-22 79.5 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease Actin PF00022.14 EIE81040.1 - 1e-25 90.0 0.0 1.9e-25 89.1 0.0 1.4 1 0 0 1 1 1 1 Actin YlbD_coat PF14071.1 EIE81040.1 - 0.13 12.3 0.2 0.13 12.3 0.2 3.3 4 1 0 4 4 4 0 Putative coat protein HHV6-IE PF03753.8 EIE81040.1 - 0.62 7.4 9.5 0.76 7.1 6.6 1.1 1 0 0 1 1 1 0 Human herpesvirus 6 immediate early protein bZIP_1 PF00170.16 EIE81041.1 - 1.6e-11 43.9 7.6 1.6e-11 43.9 5.3 1.9 2 0 0 2 2 2 1 bZIP transcription factor Aft1_OSA PF11785.3 EIE81041.1 - 1.1e-06 29.0 0.3 2.9e-06 27.7 0.1 1.8 2 0 0 2 2 2 1 Aft1 osmotic stress response (OSM) domain bZIP_2 PF07716.10 EIE81041.1 - 9.6e-06 25.3 8.8 9.6e-06 25.3 6.1 2.1 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 EIE81041.1 - 0.0038 17.4 10.2 0.0038 17.4 7.1 2.0 1 1 1 2 2 2 1 bZIP Maf transcription factor FA_desaturase PF00487.19 EIE81042.1 - 8e-51 172.9 26.5 8e-51 172.9 18.4 1.4 2 0 0 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.23 EIE81042.1 - 2.2e-15 56.1 0.0 5.8e-15 54.8 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain MFS_1 PF07690.11 EIE81042.1 - 0.48 9.0 10.2 0.2 10.3 1.6 2.1 2 0 0 2 2 2 0 Major Facilitator Superfamily TFIID_30kDa PF03540.8 EIE81043.1 - 3.2e-28 97.2 0.3 4.4e-28 96.8 0.2 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Bromo_TP PF07524.8 EIE81043.1 - 0.035 13.8 0.0 0.26 11.0 0.0 2.0 1 1 0 1 1 1 0 Bromodomain associated Antistasin PF02822.9 EIE81044.1 - 3.6 7.9 7.1 4.9 7.5 4.9 1.2 1 0 0 1 1 1 0 Antistasin family Peptidase_M50 PF02163.17 EIE81045.1 - 2.5e-06 26.5 0.1 1.3e-05 24.2 0.0 2.0 1 1 0 1 1 1 1 Peptidase family M50 cNMP_binding PF00027.24 EIE81046.1 - 9.5e-41 137.5 0.0 2.5e-19 68.8 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.12 EIE81046.1 - 2.9e-07 29.8 1.3 5.9e-07 28.8 0.9 1.5 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit DUF2708 PF10917.3 EIE81047.1 - 0.78 9.5 5.2 5.5 6.8 3.6 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2708) Gelsolin PF00626.17 EIE81049.1 - 7.7e-13 47.9 0.1 8.7e-08 31.7 0.0 3.1 3 0 0 3 3 3 2 Gelsolin repeat DUF1752 PF08550.5 EIE81050.1 - 1.7e-07 30.7 5.0 3.5e-07 29.6 3.5 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Saw1 PF11561.3 EIE81050.1 - 0.21 10.9 2.0 0.38 10.1 1.4 1.6 1 1 0 1 1 1 0 Single strand annealing-weakened 1 Cyclin PF08613.6 EIE81051.1 - 7.1e-15 55.7 0.3 1.4e-14 54.7 0.0 1.7 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 EIE81051.1 - 6.2e-06 25.7 0.1 6.2e-06 25.7 0.1 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain CDP-OH_P_transf PF01066.16 EIE81052.1 - 4.5e-17 62.2 5.0 4.5e-17 62.2 3.5 2.8 2 2 0 2 2 2 1 CDP-alcohol phosphatidyltransferase RasGAP_C PF03836.10 EIE81053.1 - 1e-36 125.7 0.6 1.4e-36 125.3 0.4 1.2 1 0 0 1 1 1 1 RasGAP C-terminus HAT PF02184.11 EIE81054.1 - 2.8e-25 87.7 66.8 6.8e-15 54.5 3.1 12.0 13 1 0 13 13 13 6 HAT (Half-A-TPR) repeat TPR_14 PF13428.1 EIE81054.1 - 1.1e-23 81.5 11.0 0.0019 18.6 0.0 9.8 7 2 5 12 12 10 5 Tetratricopeptide repeat TPR_16 PF13432.1 EIE81054.1 - 1.6e-13 50.9 6.8 0.19 12.4 0.0 7.4 5 2 2 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.1 EIE81054.1 - 1.2e-12 47.9 0.4 0.13 12.6 0.0 6.4 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.1 EIE81054.1 - 1.2e-08 34.4 1.0 0.012 15.7 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 EIE81054.1 - 1.7e-06 27.4 15.4 11 6.1 0.0 9.1 9 1 1 10 10 10 2 Tetratricopeptide repeat TPR_12 PF13424.1 EIE81054.1 - 5e-06 26.3 11.5 0.032 14.1 0.1 6.9 8 1 1 9 9 8 1 Tetratricopeptide repeat TPR_11 PF13414.1 EIE81054.1 - 0.00012 21.6 8.8 0.73 9.5 0.0 6.5 6 3 2 9 9 9 1 TPR repeat TPR_7 PF13176.1 EIE81054.1 - 0.021 14.5 10.5 33 4.6 0.1 6.6 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_6 PF13174.1 EIE81054.1 - 0.078 13.4 18.7 0.96 10.0 0.0 8.2 11 0 0 11 11 9 0 Tetratricopeptide repeat U3_assoc_6 PF08640.6 EIE81054.1 - 6.7 6.5 31.4 0.081 12.6 0.8 7.1 6 4 3 9 9 8 0 U3 small nucleolar RNA-associated protein 6 Anp1 PF03452.9 EIE81055.1 - 5.1e-78 261.9 0.0 6.3e-78 261.6 0.0 1.1 1 0 0 1 1 1 1 Anp1 SWIRM PF04433.12 EIE81056.1 - 2.1e-09 37.3 0.0 3.8e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 SWIRM domain ATG22 PF11700.3 EIE81057.1 - 1.2e-86 291.1 24.8 1.4e-86 290.9 17.2 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 EIE81057.1 - 3.8e-06 25.8 45.7 2.2e-05 23.3 8.4 2.9 1 1 2 3 3 3 3 Major Facilitator Superfamily PX PF00787.19 EIE81058.1 - 4.9e-20 71.4 0.4 4.9e-20 71.4 0.3 2.2 2 1 0 2 2 2 1 PX domain Vps5 PF09325.5 EIE81058.1 - 9.9e-16 57.7 15.0 4.9e-15 55.4 10.4 1.9 1 1 0 1 1 1 1 Vps5 C terminal like BAR PF03114.13 EIE81058.1 - 0.018 14.5 12.7 0.034 13.6 8.8 1.5 1 1 0 1 1 1 0 BAR domain PilJ PF13675.1 EIE81058.1 - 0.06 13.6 0.3 0.29 11.4 0.1 2.2 2 1 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF1517 PF07466.6 EIE81058.1 - 0.13 11.2 0.7 0.19 10.7 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) RabGAP-TBC PF00566.13 EIE81059.1 - 3.3e-46 157.4 5.8 6.4e-46 156.5 4.0 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF2616 PF11077.3 EIE81060.1 - 0.0041 16.6 1.0 0.0065 15.9 0.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2616) Prok-RING_1 PF14446.1 EIE81060.1 - 0.027 14.2 6.0 0.027 14.2 4.2 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Baculo_IE-1 PF05290.6 EIE81060.1 - 0.03 14.0 3.4 0.037 13.7 2.4 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-C3HC4_3 PF13920.1 EIE81060.1 - 0.45 10.2 12.6 1.2 8.8 8.8 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIE81060.1 - 0.46 10.5 10.6 0.55 10.3 6.7 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIE81060.1 - 0.55 10.1 14.4 1 9.2 10.0 1.5 1 1 0 1 1 1 0 Ring finger domain zf-RING_4 PF14570.1 EIE81060.1 - 4.4 6.9 10.7 22 4.7 7.4 2.2 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.1 EIE81060.1 - 5.5 6.8 13.7 12 5.7 9.3 1.8 1 1 0 1 1 1 0 zinc-RING finger domain PHD PF00628.24 EIE81060.1 - 6.3 6.5 13.2 14 5.4 9.1 1.6 1 1 0 1 1 1 0 PHD-finger Pkinase PF00069.20 EIE81061.1 - 1.4e-59 201.3 0.0 1.8e-59 200.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE81061.1 - 1.1e-24 86.8 0.0 1.7e-24 86.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIE81061.1 - 0.00015 21.5 0.0 0.00029 20.6 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EIE81061.1 - 0.073 11.8 0.4 0.1 11.3 0.3 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.9 EIE81061.1 - 0.074 12.1 0.2 0.42 9.6 0.2 1.9 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ammonium_transp PF00909.16 EIE81062.1 - 7.2e-112 373.7 20.9 8.1e-112 373.6 14.5 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Tmemb_185A PF10269.4 EIE81064.1 - 5.7e-14 52.3 29.8 1e-06 28.5 7.9 2.8 1 1 2 3 3 3 3 Transmembrane Fragile-X-F protein DUF2207 PF09972.4 EIE81064.1 - 0.046 12.3 0.3 0.046 12.3 0.2 3.1 2 1 1 3 3 3 0 Predicted membrane protein (DUF2207) DUF350 PF03994.9 EIE81065.1 - 0.02 14.6 0.3 0.054 13.2 0.1 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF350) Saccharop_dh PF03435.13 EIE81066.1 - 3.4e-23 82.2 0.0 4.6e-23 81.8 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 EIE81066.1 - 0.017 15.0 0.1 0.1 12.6 0.1 2.1 1 1 0 1 1 1 0 NADH(P)-binding Proteasome PF00227.21 EIE81067.1 - 8.8e-27 93.6 0.0 1.1e-26 93.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit AA_permease PF00324.16 EIE81068.1 - 6.3e-140 466.6 42.4 7.8e-140 466.3 29.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EIE81068.1 - 5e-47 160.4 46.0 6.1e-47 160.1 31.9 1.1 1 0 0 1 1 1 1 Amino acid permease Peptidase_M1 PF01433.15 EIE81069.1 - 2.4e-55 188.2 6.1 3.2e-34 118.6 0.0 2.9 1 1 1 2 2 2 2 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 EIE81069.1 - 2.3e-25 88.8 0.1 7.6e-25 87.1 0.0 1.8 2 0 0 2 2 2 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 EIE81069.1 - 5.6e-12 45.8 0.0 1.1e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily ATG13 PF10033.4 EIE81070.1 - 5.3e-10 39.1 1.7 8.5e-10 38.4 0.0 2.3 2 0 0 2 2 2 1 Autophagy-related protein 13 FGase PF05013.7 EIE81071.1 - 7e-10 39.1 0.1 0.0022 17.8 0.0 3.2 2 1 1 3 3 3 3 N-formylglutamate amidohydrolase TGT PF01702.13 EIE81072.1 - 8.4e-58 195.4 0.0 1e-57 195.1 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase DUF829 PF05705.9 EIE81072.1 - 0.0053 16.4 0.0 0.98 9.0 0.0 2.1 2 0 0 2 2 2 2 Eukaryotic protein of unknown function (DUF829) Pkinase PF00069.20 EIE81073.1 - 1e-72 244.4 0.1 1e-72 244.4 0.1 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE81073.1 - 1.1e-50 172.1 0.2 1.1e-50 172.1 0.1 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.23 EIE81073.1 - 7.1e-20 71.1 0.0 1.9e-19 69.7 0.0 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain PH PF00169.24 EIE81073.1 - 1.1e-12 48.0 0.3 2.6e-12 46.8 0.2 1.6 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.1 EIE81073.1 - 7.6e-06 25.0 5.7 0.0001 21.3 3.5 2.6 2 1 0 2 2 2 1 Kinase-like PH_11 PF15413.1 EIE81073.1 - 5.9e-05 23.2 3.7 0.0028 17.8 0.3 2.9 2 1 0 2 2 2 1 Pleckstrin homology domain DUF1777 PF08648.7 EIE81073.1 - 0.01 15.6 12.0 0.016 14.9 8.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) APH PF01636.18 EIE81073.1 - 0.012 15.3 2.2 0.081 12.6 0.2 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family PH_9 PF15410.1 EIE81073.1 - 0.025 14.7 0.1 13 5.9 0.0 2.8 1 1 1 2 2 2 0 Pleckstrin homology domain Peptidase_C58 PF03543.9 EIE81073.1 - 0.032 13.7 3.6 0.066 12.6 2.5 1.5 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen Pkinase PF00069.20 EIE81074.1 - 1.1e-32 113.1 0.0 1.4e-32 112.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE81074.1 - 7.2e-21 74.4 0.0 9.5e-21 74.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3128 PF11326.3 EIE81074.1 - 0.14 12.3 0.2 0.3 11.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3128) Kelch_4 PF13418.1 EIE81075.1 - 8.3e-21 73.4 3.5 5.2e-09 35.7 0.0 5.0 4 1 0 4 4 4 3 Galactose oxidase, central domain Kelch_3 PF13415.1 EIE81075.1 - 1.2e-19 69.9 1.3 9.1e-09 35.2 0.0 5.6 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.10 EIE81075.1 - 2.4e-16 58.7 1.3 1.4e-05 24.6 0.1 4.6 4 0 0 4 4 4 3 Kelch motif Kelch_5 PF13854.1 EIE81075.1 - 6.6e-16 57.8 4.2 0.0001 22.1 0.0 4.2 4 0 0 4 4 4 3 Kelch motif Kelch_1 PF01344.20 EIE81075.1 - 1.3e-15 56.6 4.6 1.5e-05 24.4 0.8 4.6 5 0 0 5 5 5 3 Kelch motif BTB PF00651.26 EIE81075.1 - 2.7e-15 56.3 0.6 6.8e-15 55.0 0.2 1.9 2 1 0 2 2 2 1 BTB/POZ domain Kelch_6 PF13964.1 EIE81075.1 - 1.7e-14 53.2 7.6 0.00089 19.3 0.2 4.9 4 0 0 4 4 4 4 Kelch motif Transcrip_reg PF01709.15 EIE81076.1 - 3.9e-73 245.4 5.9 4.4e-73 245.2 4.1 1.0 1 0 0 1 1 1 1 Transcriptional regulator Desmo_N PF06771.6 EIE81076.1 - 0.27 11.1 2.2 0.61 10.0 0.5 2.2 2 1 0 2 2 2 0 Viral Desmoplakin N-terminus RRM_1 PF00076.17 EIE81077.1 - 1.3e-15 56.8 0.1 1.9e-15 56.2 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE81077.1 - 5.5e-11 42.2 0.1 9.4e-11 41.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE81077.1 - 7.5e-07 28.8 0.0 1.3e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.18 EIE81077.1 - 0.0051 16.6 4.3 0.13 12.1 0.1 2.4 2 0 0 2 2 2 2 Zinc knuckle OB_RNB PF08206.6 EIE81077.1 - 0.011 15.1 0.4 0.036 13.5 0.3 1.9 1 0 0 1 1 1 0 Ribonuclease B OB domain Nup35_RRM_2 PF14605.1 EIE81077.1 - 0.092 12.5 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Zip PF02535.17 EIE81078.1 - 1.6e-12 47.0 21.5 1.1e-07 31.1 14.9 2.7 1 1 0 1 1 1 1 ZIP Zinc transporter DUF3147 PF11345.3 EIE81078.1 - 0.00018 21.4 1.9 0.00061 19.7 1.2 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3147) Glycophorin_A PF01102.13 EIE81078.1 - 0.1 12.3 0.2 0.59 9.9 0.0 2.0 2 0 0 2 2 2 0 Glycophorin A ABC2_membrane_5 PF13346.1 EIE81078.1 - 9.4 5.4 19.7 15 4.8 2.1 2.6 1 1 1 2 2 2 0 ABC-2 family transporter protein Pkinase PF00069.20 EIE81079.1 - 3.2e-72 242.7 0.0 4.7e-72 242.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE81079.1 - 3.9e-37 127.7 0.0 9.5e-37 126.4 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIE81079.1 - 6.6e-07 29.2 0.1 0.015 14.9 0.0 2.5 1 1 0 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 EIE81079.1 - 0.003 17.1 0.1 0.0053 16.3 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.1 EIE81079.1 - 0.0037 16.2 0.0 0.014 14.3 0.0 1.8 2 0 0 2 2 2 1 Kinase-like DUF2420 PF10336.4 EIE81081.1 - 0.084 12.4 0.5 0.13 11.8 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2420) DBD_Tnp_Mut PF03108.10 EIE81081.1 - 0.34 10.5 2.2 3.1 7.4 0.1 2.3 1 1 1 2 2 2 0 MuDR family transposase DUF953 PF06110.6 EIE81083.1 - 1.3e-21 76.2 0.0 3.1e-21 75.0 0.0 1.7 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Filament PF00038.16 EIE81083.1 - 0.011 15.2 51.3 0.12 11.7 5.5 3.0 1 1 1 2 2 2 0 Intermediate filament protein Cast PF10174.4 EIE81083.1 - 0.018 13.1 51.6 0.12 10.4 35.5 1.8 1 1 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone Reo_sigmaC PF04582.7 EIE81083.1 - 0.034 13.3 12.4 2.1 7.4 0.2 3.1 1 1 1 3 3 3 0 Reovirus sigma C capsid protein ATG16 PF08614.6 EIE81083.1 - 0.39 10.5 50.9 0.24 11.2 2.4 3.9 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) Baculo_PEP_C PF04513.7 EIE81083.1 - 1.4 8.7 24.9 0.85 9.4 1.0 4.2 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Mnd1 PF03962.10 EIE81083.1 - 2.9 7.5 47.4 0.68 9.5 6.9 3.5 1 1 2 3 3 3 0 Mnd1 family Fib_alpha PF08702.5 EIE81083.1 - 3.1 7.9 42.3 1.1 9.3 8.7 4.1 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family Tektin PF03148.9 EIE81083.1 - 4 5.8 42.6 0.65 8.4 7.1 3.7 2 1 2 4 4 4 0 Tektin family Jnk-SapK_ap_N PF09744.4 EIE81083.1 - 7.6 6.5 46.9 0.94 9.4 9.3 3.4 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 CENP-F_leu_zip PF10473.4 EIE81086.1 - 0.005 16.7 1.4 0.0097 15.7 1.0 1.4 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Golgin_A5 PF09787.4 EIE81086.1 - 0.0058 15.2 2.1 0.0069 14.9 1.1 1.3 1 1 0 1 1 1 1 Golgin subfamily A member 5 DivIVA PF05103.8 EIE81086.1 - 0.0084 16.1 1.9 0.014 15.4 1.3 1.3 1 0 0 1 1 1 1 DivIVA protein DUF3450 PF11932.3 EIE81086.1 - 0.018 14.2 2.9 0.033 13.4 2.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Herpes_UL6 PF01763.11 EIE81086.1 - 0.028 12.6 2.1 0.033 12.3 1.5 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like CCDC144C PF14915.1 EIE81086.1 - 0.034 13.0 3.3 0.045 12.6 2.3 1.2 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region IncA PF04156.9 EIE81086.1 - 0.04 13.4 1.1 0.083 12.4 0.7 1.5 1 0 0 1 1 1 0 IncA protein Apc4 PF12896.2 EIE81086.1 - 0.13 11.5 0.8 0.19 11.0 0.3 1.4 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 4 TMF_TATA_bd PF12325.3 EIE81086.1 - 0.14 11.8 1.8 0.23 11.2 0.8 1.7 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DivIC PF04977.10 EIE81086.1 - 0.15 11.5 1.0 0.38 10.2 0.7 1.7 1 0 0 1 1 1 0 Septum formation initiator TBPIP PF07106.8 EIE81086.1 - 0.16 11.4 2.6 0.21 11.1 1.0 1.6 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) CCDC155 PF14662.1 EIE81086.1 - 0.18 11.3 3.8 0.058 12.9 0.7 1.7 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 Filament PF00038.16 EIE81086.1 - 0.32 10.3 3.9 0.29 10.5 1.8 1.4 1 1 0 1 1 1 0 Intermediate filament protein Spc24 PF08286.6 EIE81086.1 - 0.36 10.5 2.8 0.56 9.9 2.0 1.6 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 Cast PF10174.4 EIE81086.1 - 0.61 8.0 5.5 0.29 9.1 2.3 1.3 1 1 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone GET2 PF08690.5 EIE81086.1 - 0.72 9.0 4.3 0.88 8.7 2.9 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 FliJ PF02050.11 EIE81086.1 - 3.5 7.7 10.0 0.12 12.4 2.3 1.8 2 0 0 2 2 2 0 Flagellar FliJ protein Tim17 PF02466.14 EIE81087.1 - 2.1e-14 53.6 16.2 9.2e-11 41.8 3.5 2.2 1 1 1 2 2 2 2 Tim17/Tim22/Tim23/Pmp24 family DUF2104 PF09877.4 EIE81087.1 - 0.051 13.5 0.0 0.061 13.2 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2104) DUF543 PF04418.7 EIE81087.1 - 0.087 12.7 0.0 0.087 12.7 0.0 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF543) Gly-zipper_Omp PF13488.1 EIE81087.1 - 1.6 8.4 10.7 3.3 7.4 4.1 2.2 2 0 0 2 2 2 0 Glycine zipper Bacteriocin_IIc PF10439.4 EIE81087.1 - 3.4 7.8 13.1 2.2 8.4 0.2 2.2 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Pex24p PF06398.6 EIE81088.1 - 8.5e-26 90.5 4.0 1.2e-25 90.0 2.8 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin C1_1 PF00130.17 EIE81088.1 - 1.8e-11 43.5 10.9 4.2e-11 42.3 7.5 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) 7tm_1 PF00001.16 EIE81088.1 - 0.0086 15.2 0.1 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) PHD PF00628.24 EIE81088.1 - 0.059 13.0 6.5 0.15 11.7 4.5 1.8 1 0 0 1 1 1 0 PHD-finger TMEM154 PF15102.1 EIE81088.1 - 0.089 12.5 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family Methyltransf_16 PF10294.4 EIE81089.1 - 1.1e-23 83.5 0.0 1.5e-23 83.1 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_12 PF08242.7 EIE81089.1 - 0.025 15.0 0.0 0.046 14.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 EIE81089.1 - 0.096 12.2 0.0 0.28 10.7 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_18 PF12847.2 EIE81089.1 - 0.12 12.9 0.0 0.32 11.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Mito_carr PF00153.22 EIE81090.1 - 5.1e-58 192.7 0.3 8.1e-27 92.7 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_6 PF13405.1 EIE81090.1 - 0.0014 18.3 0.0 0.0042 16.8 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.27 EIE81090.1 - 0.0018 17.4 0.1 0.011 14.9 0.0 2.3 2 0 0 2 2 2 1 EF hand LETM1 PF07766.8 EIE81090.1 - 0.056 12.4 0.3 0.08 11.9 0.2 1.1 1 0 0 1 1 1 0 LETM1-like protein EF-hand_5 PF13202.1 EIE81090.1 - 0.14 11.5 0.4 0.33 10.3 0.3 1.6 1 0 0 1 1 1 0 EF hand Pkinase PF00069.20 EIE81091.1 - 2.7e-39 134.8 0.0 4.2e-39 134.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE81091.1 - 2.9e-13 49.5 0.0 4.2e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIE81091.1 - 5.9e-06 26.1 0.1 0.0053 16.5 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family MFS_1 PF07690.11 EIE81092.1 - 0.0085 14.8 13.3 0.6 8.7 10.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF872 PF05915.7 EIE81092.1 - 0.011 15.5 0.0 0.029 14.2 0.0 1.7 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) G6PD_C PF02781.11 EIE81093.1 - 2.8e-119 397.3 0.0 4.8e-119 396.5 0.0 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain Mitofilin PF09731.4 EIE81093.1 - 7e-89 299.0 43.2 1.7e-81 274.6 25.5 2.8 1 1 1 2 2 2 2 Mitochondrial inner membrane protein G6PD_N PF00479.17 EIE81093.1 - 6.4e-58 196.0 0.3 6.4e-58 196.0 0.2 3.3 3 2 0 3 3 3 1 Glucose-6-phosphate dehydrogenase, NAD binding domain PAS PF00989.19 EIE81095.1 - 1.9e-11 43.7 0.0 4.9e-07 29.5 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_3 PF08447.6 EIE81095.1 - 1e-09 38.3 0.0 9.2e-09 35.2 0.0 2.2 2 0 0 2 2 2 1 PAS fold PAS_11 PF14598.1 EIE81095.1 - 4e-09 36.4 0.0 1.6e-07 31.2 0.0 2.4 2 0 0 2 2 2 1 PAS domain PAS_9 PF13426.1 EIE81095.1 - 9.8e-09 35.5 0.0 0.00087 19.6 0.0 2.6 2 1 0 3 3 3 2 PAS domain PAS_4 PF08448.5 EIE81095.1 - 0.0048 16.9 0.0 1 9.4 0.0 2.3 2 0 0 2 2 2 2 PAS fold zf-H2C2_2 PF13465.1 EIE81096.1 - 4.4e-09 36.1 18.4 1.2e-06 28.4 1.2 3.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 EIE81096.1 - 1.3e-06 28.4 19.6 0.00034 20.7 1.6 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIE81096.1 - 0.0002 21.4 13.5 0.04 14.2 1.4 3.0 3 0 0 3 3 2 2 C2H2-type zinc finger zf-met PF12874.2 EIE81096.1 - 0.023 14.9 7.1 0.037 14.2 1.0 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Na_trans_assoc PF06512.8 EIE81096.1 - 0.17 11.8 3.5 0.21 11.5 2.5 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated DUF605 PF04652.11 EIE81096.1 - 0.69 9.2 10.4 0.75 9.1 7.2 1.1 1 0 0 1 1 1 0 Vta1 like ORC6 PF05460.8 EIE81096.1 - 0.7 8.9 9.6 0.76 8.8 6.7 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Herpes_DNAp_acc PF04929.7 EIE81096.1 - 0.71 8.7 6.0 0.94 8.3 4.2 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor zf-C2H2_jaz PF12171.3 EIE81096.1 - 0.9 9.7 7.0 0.3 11.2 0.9 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 EIE81096.1 - 2.1 8.1 6.4 5.6 6.8 0.8 2.5 2 0 0 2 2 2 0 BED zinc finger zf-Di19 PF05605.7 EIE81096.1 - 4.8 7.3 7.1 0.58 10.3 1.9 1.8 2 0 0 2 2 1 0 Drought induced 19 protein (Di19), zinc-binding p450 PF00067.17 EIE81097.1 - 2.3e-78 263.7 0.0 2.8e-78 263.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1777 PF08648.7 EIE81099.1 - 0.043 13.5 29.9 0.045 13.4 20.4 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1777) THRAP3_BCLAF1 PF15440.1 EIE81099.1 - 0.11 11.1 19.5 0.13 10.8 13.5 1.1 1 0 0 1 1 1 0 THRAP3/BCLAF1 family Transposase_24 PF03004.9 EIE81099.1 - 1.4 8.7 6.4 1.1 9.1 3.4 1.6 1 1 0 1 1 1 0 Plant transposase (Ptta/En/Spm family) DUF566 PF04484.7 EIE81099.1 - 3.2 7.1 7.8 3.4 7.0 5.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) Dynamin_M PF01031.15 EIE81100.1 - 6.3e-104 346.9 0.0 1e-103 346.1 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 EIE81100.1 - 5.3e-49 166.2 0.8 7.7e-49 165.7 0.0 1.7 2 0 0 2 2 2 1 Dynamin family GED PF02212.13 EIE81100.1 - 1e-31 108.6 3.3 5.8e-30 103.0 1.3 2.7 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EIE81100.1 - 0.018 15.0 0.1 0.056 13.4 0.1 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase zf-CCHC_4 PF14392.1 EIE81100.1 - 0.12 12.0 0.0 0.3 10.8 0.0 1.6 1 0 0 1 1 1 0 Zinc knuckle Ricin_B_lectin PF00652.17 EIE81101.1 - 8.6e-58 193.7 20.3 1.7e-08 34.5 0.0 15.5 9 4 5 14 14 14 13 Ricin-type beta-trefoil lectin domain HAD_2 PF13419.1 EIE81101.1 - 4e-07 30.4 0.1 1.3e-06 28.7 0.1 2.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase SBF PF01758.11 EIE81102.1 - 2e-51 174.0 10.4 2e-51 174.0 7.2 2.1 3 0 0 3 3 3 1 Sodium Bile acid symporter family Ytp1 PF10355.4 EIE81103.1 - 1.1e-13 50.9 6.6 5.5e-13 48.7 2.7 2.9 3 1 0 3 3 3 1 Protein of unknown function (Ytp1) YtpI PF14007.1 EIE81103.1 - 0.024 14.5 1.0 0.21 11.5 0.4 2.5 2 0 0 2 2 2 0 YtpI-like protein NDUF_C2 PF06374.6 EIE81103.1 - 0.032 14.2 0.1 9.6 6.2 0.1 2.5 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) SPC12 PF06645.8 EIE81103.1 - 0.12 12.2 1.0 0.57 10.0 0.7 2.1 1 0 0 1 1 1 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Ni_hydr_CYTB PF01292.15 EIE81103.1 - 0.24 10.7 0.0 0.24 10.7 0.0 2.9 1 1 0 2 2 2 0 Prokaryotic cytochrome b561 YfhO PF09586.5 EIE81103.1 - 2.6 5.9 6.4 5.7 4.8 4.4 1.6 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Asp PF00026.18 EIE81105.1 - 2.9e-55 187.7 0.0 3.4e-55 187.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIE81105.1 - 1.4e-06 28.3 0.1 0.00012 22.0 0.1 3.1 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EIE81105.1 - 0.0067 16.8 0.1 7.8 7.0 0.1 3.1 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 EIE81105.1 - 0.07 12.6 0.1 0.42 10.1 0.1 2.2 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal GATA PF00320.22 EIE81106.1 - 7.2e-17 60.4 2.4 1.4e-16 59.5 1.7 1.5 1 0 0 1 1 1 1 GATA zinc finger zf-RING_3 PF14369.1 EIE81106.1 - 0.0027 17.6 1.0 0.0075 16.2 0.7 1.7 1 0 0 1 1 1 1 zinc-finger RRN7 PF11781.3 EIE81106.1 - 0.0051 16.2 1.3 0.0093 15.4 0.9 1.4 1 0 0 1 1 1 1 RNA polymerase I-specific transcription initiation factor Rrn7 TF_Zn_Ribbon PF08271.7 EIE81106.1 - 0.0057 15.9 1.4 0.012 14.9 0.9 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding zf-Sec23_Sec24 PF04810.10 EIE81106.1 - 0.07 12.7 2.1 0.087 12.3 0.7 1.8 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Peptidase_S10 PF00450.17 EIE81107.1 - 1.5e-58 198.9 2.2 2.1e-58 198.4 1.5 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase HD PF01966.17 EIE81108.1 - 4.8e-07 29.8 0.0 2.3e-06 27.6 0.0 2.2 2 1 0 2 2 2 1 HD domain DUF962 PF06127.6 EIE81108.1 - 1 9.3 4.1 5 7.0 0.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF962) HSF_DNA-bind PF00447.12 EIE81109.1 - 1.6e-37 127.8 3.1 4.1e-37 126.5 2.2 1.7 1 0 0 1 1 1 1 HSF-type DNA-binding LSM PF01423.17 EIE81110.1 - 1.4e-15 56.5 0.0 2.1e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EIE81110.1 - 0.034 14.0 0.0 0.053 13.4 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain Response_reg PF00072.19 EIE81111.1 - 1.9e-14 53.6 1.0 1.2e-13 51.0 0.7 2.1 1 1 0 1 1 1 1 Response regulator receiver domain Peptidase_U57 PF05582.7 EIE81111.1 - 0.0011 18.0 0.9 0.0013 17.7 0.7 1.2 1 0 0 1 1 1 1 YabG peptidase U57 DAD PF02109.11 EIE81112.1 - 1.2e-45 154.1 1.4 1.4e-45 153.9 0.9 1.0 1 0 0 1 1 1 1 DAD family ATP_synt_I PF03899.10 EIE81112.1 - 0.014 15.5 0.9 0.019 15.1 0.6 1.3 1 0 0 1 1 1 0 ATP synthase I chain 7TM_GPCR_Srx PF10328.4 EIE81112.1 - 0.035 13.1 0.1 0.035 13.1 0.1 1.7 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx DUF4389 PF14333.1 EIE81112.1 - 0.081 12.6 0.3 0.14 11.9 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4389) ADH_N PF08240.7 EIE81113.1 - 3e-22 78.4 2.2 4.6e-22 77.8 1.5 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIE81113.1 - 1.5e-20 73.0 0.0 2.9e-20 72.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIE81113.1 - 0.00014 22.7 0.0 0.0003 21.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EIE81113.1 - 0.0053 15.9 0.0 0.0084 15.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EIE81113.1 - 0.052 13.1 0.0 0.093 12.2 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain XdhC_C PF13478.1 EIE81113.1 - 0.069 13.4 0.0 0.33 11.2 0.0 1.9 2 0 0 2 2 2 0 XdhC Rossmann domain ThiF PF00899.16 EIE81113.1 - 0.68 9.7 2.4 1.1 9.0 1.1 1.7 2 0 0 2 2 2 0 ThiF family Fer4_4 PF12800.2 EIE81113.1 - 7.6 7.1 6.6 3.5 8.1 0.9 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain MatE PF01554.13 EIE81115.1 - 2.9e-45 153.7 19.2 1.1e-24 86.8 2.7 3.0 4 0 0 4 4 4 2 MatE Polysacc_synt_C PF14667.1 EIE81115.1 - 1.5e-08 34.6 14.3 1.5e-08 34.6 9.9 3.8 3 1 1 4 4 4 2 Polysaccharide biosynthesis C-terminal domain Phage_Gp23 PF10669.4 EIE81115.1 - 0.063 13.3 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) IGR PF09597.5 EIE81116.1 - 2.4e-06 27.3 0.0 3.3e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 IGR protein motif Rieske PF00355.21 EIE81117.1 - 1.2e-06 28.0 0.1 2.3e-06 27.1 0.1 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain DNA_pol_viral_N PF00242.12 EIE81117.1 - 0.0075 15.3 7.2 0.0096 14.9 5.0 1.1 1 0 0 1 1 1 1 DNA polymerase (viral) N-terminal domain Tmemb_cc2 PF10267.4 EIE81117.1 - 0.021 13.4 8.7 0.029 12.9 6.0 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Na_trans_assoc PF06512.8 EIE81117.1 - 0.085 12.8 6.9 0.13 12.2 4.8 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated Presenilin PF01080.12 EIE81117.1 - 8.7 5.0 6.3 12 4.5 4.4 1.3 1 0 0 1 1 1 0 Presenilin DDE_3 PF13358.1 EIE81118.1 - 3.1e-20 72.4 0.0 1.5e-19 70.1 0.0 2.0 1 1 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE81118.1 - 0.037 14.1 0.0 0.076 13.1 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain DDE_1 PF03184.14 EIE81119.1 - 1.3e-25 89.8 0.5 2.9e-25 88.7 0.4 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_3 PF13358.1 EIE81119.1 - 0.0027 17.4 0.0 0.0062 16.2 0.0 1.7 1 1 0 1 1 1 1 DDE superfamily endonuclease Thy1 PF02511.10 EIE81121.1 - 0.035 13.4 0.6 0.073 12.4 0.4 1.6 1 1 0 1 1 1 0 Thymidylate synthase complementing protein Baculo_VP1054 PF05789.6 EIE81121.1 - 0.13 11.4 0.6 0.21 10.7 0.4 1.3 1 0 0 1 1 1 0 Baculovirus VP1054 protein Cyclin_C PF02984.14 EIE81124.1 - 0.014 15.2 0.3 0.016 15.1 0.2 1.1 1 0 0 1 1 1 0 Cyclin, C-terminal domain HHH_2 PF12826.2 EIE81124.1 - 0.13 12.1 0.1 0.17 11.7 0.1 1.3 1 1 0 1 1 1 0 Helix-hairpin-helix motif Chordopox_G3 PF06129.7 EIE81125.1 - 0.15 12.2 0.3 0.64 10.1 0.0 2.0 2 0 0 2 2 2 0 Chordopoxvirus G3 protein Fib_alpha PF08702.5 EIE81126.1 - 0.043 13.9 0.4 0.063 13.3 0.3 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family OPT PF03169.10 EIE81127.1 - 0.0052 15.2 1.0 0.0062 15.0 0.7 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4231 PF14015.1 EIE81127.1 - 0.031 14.2 0.8 0.044 13.7 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) ABC2_membrane_2 PF12679.2 EIE81127.1 - 0.058 12.2 0.3 0.074 11.9 0.2 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF3754 PF12576.3 EIE81127.1 - 0.079 12.5 0.6 0.14 11.8 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3754) MRP-L28 PF09812.4 EIE81128.1 - 2.4e-17 63.2 2.6 2.7e-17 63.0 1.8 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 Med12-LCEWAV PF12145.3 EIE81128.1 - 0.0068 14.9 0.1 0.0078 14.7 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic Mediator 12 subunit domain DUF241 PF03087.9 EIE81128.1 - 0.058 12.8 2.0 0.067 12.6 1.4 1.2 1 0 0 1 1 1 0 Arabidopsis protein of unknown function Sec63 PF02889.11 EIE81129.1 - 2.1e-94 316.2 0.4 3.3e-94 315.6 0.3 1.3 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.24 EIE81129.1 - 1.1e-42 145.3 0.0 8.9e-29 100.1 0.2 3.6 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.10 EIE81129.1 - 4.3e-12 46.2 4.3 2.6e-08 33.9 0.0 3.7 3 1 0 3 3 3 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EIE81129.1 - 1.2e-07 31.4 0.0 7.1e-07 29.0 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 EIE81129.1 - 1.1e-06 28.2 0.0 0.04 13.6 0.0 2.6 2 0 0 2 2 2 2 Part of AAA domain AAA_22 PF13401.1 EIE81129.1 - 8.6e-05 22.6 2.3 0.063 13.4 0.2 3.9 3 2 0 3 3 3 2 AAA domain AAA_30 PF13604.1 EIE81129.1 - 0.00016 21.3 0.0 0.37 10.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 EIE81129.1 - 0.0009 18.7 0.0 4.3 6.7 0.0 4.4 4 0 0 4 4 4 1 IstB-like ATP binding protein ATP-synt_F PF01990.12 EIE81130.1 - 0.074 13.4 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 ATP synthase (F/14-kDa) subunit Gp_dh_C PF02800.15 EIE81131.1 - 1.8e-73 245.1 0.0 2.8e-73 244.5 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 EIE81131.1 - 7.5e-59 198.0 0.1 1.6e-58 196.9 0.0 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain ADH_zinc_N PF00107.21 EIE81131.1 - 0.012 15.1 0.0 0.024 14.2 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DUF2436 PF10365.4 EIE81131.1 - 0.031 13.9 0.2 0.059 12.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2436) Ferrochelatase PF00762.14 EIE81132.1 - 3.1e-108 361.4 0.0 3.6e-108 361.2 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase CbiX PF01903.12 EIE81132.1 - 0.00068 19.7 0.0 1.5 8.9 0.0 3.3 3 0 0 3 3 3 1 CbiX LLC1 PF14945.1 EIE81132.1 - 0.067 13.5 0.2 0.84 9.9 0.0 2.3 2 0 0 2 2 2 0 Normal lung function maintenance, Low in Lung Cancer 1 protein DUF1752 PF08550.5 EIE81133.1 - 6.5e-13 48.0 0.5 1.1e-12 47.2 0.3 1.4 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Polysacc_deac_1 PF01522.16 EIE81134.1 - 2.1e-30 104.8 0.0 3.3e-30 104.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase NPR2 PF06218.6 EIE81135.1 - 5.2e-40 137.4 1.4 6.4e-40 137.1 0.9 1.0 1 0 0 1 1 1 1 Nitrogen permease regulator 2 Afi1 PF07792.7 EIE81135.1 - 0.00032 20.7 0.1 0.00055 19.9 0.0 1.4 2 0 0 2 2 2 1 Docking domain of Afi1 for Arf3 in vesicle trafficking RPAP1_C PF08620.5 EIE81137.1 - 2.1e-23 81.9 0.0 2.6e-22 78.4 0.0 2.5 2 0 0 2 2 2 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 EIE81137.1 - 8.8e-07 28.4 5.2 2.5e-06 26.9 3.6 1.8 1 0 0 1 1 1 1 RPAP1-like, N-terminal RhoGAP PF00620.22 EIE81138.1 - 1.1e-22 80.3 0.1 4.5e-22 78.2 0.1 2.1 2 0 0 2 2 2 1 RhoGAP domain DnaG_DnaB_bind PF08278.6 EIE81139.1 - 0.052 13.7 0.1 0.052 13.7 0.1 1.0 1 0 0 1 1 1 0 DNA primase DnaG DnaB-binding GFO_IDH_MocA PF01408.17 EIE81141.1 - 2.4e-25 89.3 0.3 4.8e-25 88.4 0.2 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.12 EIE81141.1 - 0.0013 19.1 0.1 0.004 17.5 0.0 1.9 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA_C PF02894.12 EIE81141.1 - 0.0084 15.8 0.2 0.018 14.8 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain Shikimate_DH PF01488.15 EIE81141.1 - 0.013 15.6 0.5 0.59 10.2 0.1 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_3 PF03447.11 EIE81141.1 - 0.12 12.7 0.3 0.27 11.6 0.1 1.7 2 0 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain RhoGEF PF00621.15 EIE81142.1 - 1.3e-19 70.7 5.6 7.3e-15 55.3 0.2 3.0 2 1 1 3 3 3 2 RhoGEF domain PH PF00169.24 EIE81142.1 - 0.00012 22.1 2.5 0.00088 19.4 0.3 2.8 1 1 1 2 2 2 1 PH domain Cullin_binding PF03556.10 EIE81142.1 - 0.023 14.8 0.8 0.069 13.2 0.1 2.2 2 1 0 2 2 2 0 Cullin binding Glyco_hydro_28 PF00295.12 EIE81144.1 - 1.7e-56 191.5 12.7 2.4e-56 191.0 8.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Proteasome PF00227.21 EIE81145.1 - 3.2e-52 176.5 0.7 3.7e-52 176.3 0.5 1.0 1 0 0 1 1 1 1 Proteasome subunit WD40 PF00400.27 EIE81146.1 - 2.5e-11 43.0 0.9 3.2e-08 33.1 0.0 4.5 4 1 0 4 4 4 1 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EIE81146.1 - 0.012 14.3 0.1 0.05 12.3 0.0 1.9 1 1 0 1 1 1 0 Nup133 N terminal like CMAS PF02353.15 EIE81147.1 - 1.6e-65 220.8 1.8 2e-65 220.6 1.3 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.7 EIE81147.1 - 1.6e-10 41.3 0.0 3.3e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIE81147.1 - 3e-09 36.7 0.1 6.5e-09 35.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIE81147.1 - 2.7e-07 30.2 0.0 4.6e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EIE81147.1 - 4.3e-07 29.4 0.0 6.8e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 EIE81147.1 - 5.8e-07 29.9 0.0 1.1e-06 29.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIE81147.1 - 9.8e-07 29.0 0.0 2e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIE81147.1 - 3.6e-05 24.3 0.0 6.8e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIE81147.1 - 0.00021 21.3 0.0 0.00049 20.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 EIE81147.1 - 0.00036 19.9 0.0 0.00063 19.1 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 PCMT PF01135.14 EIE81147.1 - 0.0042 16.6 0.0 0.0069 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.8 EIE81147.1 - 0.0077 15.3 0.0 0.013 14.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 EIE81147.1 - 0.02 13.9 0.0 0.035 13.2 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Mito_carr PF00153.22 EIE81148.1 - 4.6e-58 192.9 5.3 2.9e-19 68.5 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein PrcB_C PF14343.1 EIE81148.1 - 0.015 14.9 0.1 0.55 9.9 0.1 2.4 2 0 0 2 2 2 0 PrcB C-terminal peroxidase PF00141.18 EIE81149.1 - 2e-45 155.0 0.0 2.9e-45 154.5 0.0 1.2 1 0 0 1 1 1 1 Peroxidase MotB_plug PF13677.1 EIE81149.1 - 0.018 14.3 0.8 0.33 10.3 0.1 2.3 2 0 0 2 2 2 0 Membrane MotB of proton-channel complex MotA/MotB Sel1 PF08238.7 EIE81150.1 - 1.5e-133 432.3 98.1 1.3e-08 35.1 0.1 32.4 34 0 0 34 34 34 24 Sel1 repeat TPR_11 PF13414.1 EIE81150.1 - 0.0094 15.5 88.7 0.74 9.5 0.2 15.7 12 4 5 17 17 17 8 TPR repeat TPR_16 PF13432.1 EIE81150.1 - 0.22 12.2 96.8 0.24 12.1 2.1 17.5 13 6 7 21 21 21 0 Tetratricopeptide repeat TPR_12 PF13424.1 EIE81150.1 - 0.73 9.8 69.7 0.84 9.6 1.3 14.9 13 5 2 15 15 15 0 Tetratricopeptide repeat TPR_14 PF13428.1 EIE81150.1 - 0.89 10.3 57.1 2.3 9.1 0.1 13.9 12 3 2 14 14 14 0 Tetratricopeptide repeat Oxysterol_BP PF01237.13 EIE81151.1 - 2.5e-81 272.9 0.2 2.5e-81 272.9 0.2 2.0 2 0 0 2 2 2 1 Oxysterol-binding protein RRM_1 PF00076.17 EIE81152.1 - 1.5e-33 114.2 0.3 3.1e-17 61.9 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE81152.1 - 5.2e-28 96.8 0.0 2.4e-13 49.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE81152.1 - 5.8e-13 48.4 0.6 2.6e-07 30.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EIE81152.1 - 0.00013 21.6 0.3 0.011 15.4 0.0 2.4 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif TFIIF_alpha PF05793.7 EIE81152.1 - 0.17 10.2 34.4 0.55 8.5 21.5 2.3 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Hid1 PF12722.2 EIE81152.1 - 1.5 6.4 9.2 1.7 6.2 6.4 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein IclR PF01614.13 EIE81152.1 - 3.2 7.4 5.1 6.7 6.4 3.5 1.6 1 0 0 1 1 1 0 Bacterial transcriptional regulator RVT_1 PF00078.22 EIE81153.1 - 5.7e-16 58.5 0.1 1.1e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PRP1_N PF06424.7 EIE81155.1 - 0.65 10.3 13.9 0.67 10.2 0.4 2.9 3 0 0 3 3 3 0 PRP1 splicing factor, N-terminal Phage_integrase PF00589.17 EIE81156.1 - 3.1e-07 30.2 0.3 8.9e-07 28.7 0.1 1.8 2 0 0 2 2 2 1 Phage integrase family DUF2981 PF11200.3 EIE81157.1 - 0.11 11.5 0.1 0.12 11.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) SAC3_GANP PF03399.11 EIE81159.1 - 2.8e-49 167.4 2.2 4.1e-49 166.9 1.5 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family rve PF00665.21 EIE81160.1 - 2.7e-23 82.3 0.0 6.8e-23 81.0 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE81160.1 - 8.1e-16 58.0 0.3 1.9e-15 56.7 0.2 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE81160.1 - 3.9e-11 42.4 1.1 8.8e-11 41.3 0.7 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.12 EIE81160.1 - 0.00046 20.2 0.9 0.0022 18.0 0.6 2.2 1 0 0 1 1 1 1 Retrotransposon gag protein zf-H2C2 PF09337.5 EIE81160.1 - 0.0013 18.1 0.1 0.0038 16.6 0.1 1.9 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger UBN2_2 PF14227.1 EIE81160.1 - 0.0038 16.7 2.3 0.045 13.2 0.0 3.2 3 0 0 3 3 3 1 gag-polypeptide of LTR copia-type rve_3 PF13683.1 EIE81160.1 - 0.0068 15.9 0.2 0.046 13.2 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain UBN2 PF14223.1 EIE81160.1 - 0.047 13.4 0.3 0.2 11.4 0.1 2.2 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type Cpn60_TCP1 PF00118.19 EIE81161.1 - 1.9e-144 481.8 15.6 2.2e-144 481.7 10.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sua5_yciO_yrdC PF01300.13 EIE81161.1 - 0.016 14.4 0.2 0.089 12.0 0.0 2.1 2 0 0 2 2 2 0 Telomere recombination DUF3722 PF12519.3 EIE81162.1 - 1.1e-22 80.5 0.2 3.1e-18 65.9 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3722) GnsAB PF08178.6 EIE81162.1 - 0.12 12.0 0.0 1.6 8.4 0.0 2.0 2 0 0 2 2 2 0 GnsA/GnsB family ABC_membrane PF00664.18 EIE81163.1 - 1.2e-96 323.3 29.9 4.1e-51 174.0 11.2 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EIE81163.1 - 1.4e-71 239.1 0.7 1.8e-35 122.1 0.0 4.0 4 0 0 4 4 4 2 ABC transporter SMC_N PF02463.14 EIE81163.1 - 8.4e-16 57.8 0.0 9e-08 31.6 0.0 3.9 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.4 EIE81163.1 - 1.3e-09 37.1 0.4 0.00027 19.6 0.0 2.7 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_21 PF13304.1 EIE81163.1 - 1.3e-09 38.4 0.0 0.42 10.5 0.0 4.7 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.1 EIE81163.1 - 1.7e-09 37.9 1.9 0.0024 17.8 0.1 3.2 2 2 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 EIE81163.1 - 1.5e-08 34.8 1.3 0.0044 17.1 0.1 4.2 3 2 0 3 3 2 2 AAA domain AAA_29 PF13555.1 EIE81163.1 - 1.1e-07 31.2 0.2 0.017 14.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EIE81163.1 - 3.9e-07 29.4 0.0 0.03 13.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA PF00004.24 EIE81163.1 - 8.8e-07 29.1 0.3 1 9.5 0.0 4.3 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EIE81163.1 - 3.2e-06 27.9 0.0 0.21 12.3 0.0 3.3 3 0 0 3 3 2 2 AAA domain AAA_30 PF13604.1 EIE81163.1 - 2.6e-05 23.8 0.5 1.8 8.0 0.2 4.0 3 1 0 3 3 3 2 AAA domain AAA_33 PF13671.1 EIE81163.1 - 5.1e-05 23.1 0.0 0.5 10.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 EIE81163.1 - 7e-05 22.6 2.7 0.13 12.1 0.2 3.8 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.1 EIE81163.1 - 0.00035 20.0 0.1 1.8 7.9 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_10 PF12846.2 EIE81163.1 - 0.00037 20.0 2.0 0.58 9.5 0.1 3.4 3 0 0 3 3 3 1 AAA-like domain MobB PF03205.9 EIE81163.1 - 0.00074 19.2 0.1 1.4 8.6 0.0 2.8 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 EIE81163.1 - 0.002 17.2 0.1 0.3 10.1 0.0 2.7 3 0 0 3 3 2 1 Zeta toxin SRP54 PF00448.17 EIE81163.1 - 0.0022 17.4 0.0 0.23 10.8 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Rad17 PF03215.10 EIE81163.1 - 0.0024 16.6 0.1 0.11 11.1 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein RNA_helicase PF00910.17 EIE81163.1 - 0.005 16.9 0.0 3.9 7.7 0.0 3.1 2 0 0 2 2 2 1 RNA helicase AAA_5 PF07728.9 EIE81163.1 - 0.006 16.3 0.2 8.5 6.1 0.0 3.5 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) G-alpha PF00503.15 EIE81163.1 - 0.0072 15.0 6.1 0.13 10.8 0.0 2.8 3 0 0 3 3 2 2 G-protein alpha subunit AAA_28 PF13521.1 EIE81163.1 - 0.0083 16.1 0.0 2 8.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EIE81163.1 - 0.0092 16.2 0.0 6.7 7.0 0.0 3.0 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EIE81163.1 - 0.011 15.6 0.0 3.3 7.6 0.0 3.4 4 0 0 4 4 3 0 AAA domain AAA_19 PF13245.1 EIE81163.1 - 0.016 14.9 1.2 2.5 7.9 0.0 3.3 3 0 0 3 3 3 0 Part of AAA domain Chitin_synth_1 PF01644.12 EIE81163.1 - 0.042 13.6 5.0 8.8 6.0 0.1 4.0 4 0 0 4 4 4 0 Chitin synthase NACHT PF05729.7 EIE81163.1 - 0.042 13.5 0.1 13 5.4 0.0 2.9 2 0 0 2 2 2 0 NACHT domain MMR_HSR1 PF01926.18 EIE81163.1 - 0.065 13.1 0.9 8.7 6.3 0.0 3.4 3 1 0 3 3 3 0 50S ribosome-binding GTPase GMC_oxred_N PF00732.14 EIE81163.1 - 0.071 12.2 0.1 0.61 9.1 0.0 2.2 2 0 0 2 2 2 0 GMC oxidoreductase IF-2B PF01008.12 EIE81164.1 - 1.5e-74 250.4 3.1 1.8e-74 250.2 2.2 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family Peripla_BP_1 PF00532.16 EIE81164.1 - 0.016 14.4 0.6 0.83 8.8 0.0 2.5 2 1 0 2 2 2 0 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_4 PF13407.1 EIE81164.1 - 0.017 14.4 1.8 0.031 13.6 0.5 2.2 1 1 0 1 1 1 0 Periplasmic binding protein domain Ribosomal_S28e PF01200.13 EIE81165.1 - 5.7e-34 115.6 2.6 6.2e-34 115.5 1.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e PDEase_I PF00233.14 EIE81166.1 - 3.5e-39 134.9 7.9 1.1e-37 130.0 5.5 2.1 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.17 EIE81166.1 - 6.9e-06 26.0 1.3 1.6e-05 24.9 0.1 2.2 2 0 0 2 2 2 1 HD domain Asp PF00026.18 EIE81167.1 - 4.8e-40 137.7 0.0 6.1e-40 137.4 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIE81167.1 - 2e-08 34.3 0.0 1.5e-07 31.4 0.0 1.9 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal DUF106 PF01956.11 EIE81168.1 - 4.4e-55 185.7 1.6 6.7e-55 185.1 1.1 1.3 1 0 0 1 1 1 1 Integral membrane protein DUF106 TP6A_N PF04406.9 EIE81169.1 - 2.4e-10 39.9 0.2 5e-10 38.9 0.1 1.5 1 0 0 1 1 1 1 Type IIB DNA topoisomerase MitMem_reg PF13012.1 EIE81170.1 - 6e-41 139.1 1.3 8.8e-41 138.6 0.4 1.7 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.16 EIE81170.1 - 6.4e-30 103.2 0.0 1.3e-29 102.2 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Ribosomal_L7Ae PF01248.21 EIE81170.1 - 1.9e-09 36.9 0.2 4.4e-09 35.7 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family FANCL_C PF11793.3 EIE81170.1 - 0.038 13.9 0.3 0.32 10.9 0.2 2.2 2 0 0 2 2 2 0 FANCL C-terminal domain UQ_con PF00179.21 EIE81171.1 - 6.6e-49 164.9 0.0 7.8e-49 164.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EIE81171.1 - 1.7e-06 27.8 0.0 2.1e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EIE81171.1 - 0.0072 16.2 0.2 0.011 15.6 0.1 1.6 1 1 0 1 1 1 1 RWD domain UEV PF05743.8 EIE81171.1 - 0.045 13.4 0.0 0.071 12.7 0.0 1.3 1 0 0 1 1 1 0 UEV domain DUF1615 PF07759.7 EIE81172.1 - 0.049 12.3 0.1 0.1 11.3 0.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1615) HAP1_N PF04849.8 EIE81173.1 - 0.011 14.7 1.0 0.013 14.4 0.7 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region DUF3416 PF11896.3 EIE81173.1 - 0.014 15.3 0.4 0.016 15.1 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3416) ArdA PF07275.6 EIE81173.1 - 0.021 15.0 0.4 0.025 14.8 0.2 1.0 1 0 0 1 1 1 0 Antirestriction protein (ArdA) Baculo_PEP_C PF04513.7 EIE81173.1 - 0.033 13.9 0.3 0.043 13.6 0.2 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Synaphin PF05835.7 EIE81173.1 - 0.068 13.3 1.3 0.096 12.8 0.8 1.3 1 1 0 1 1 1 0 Synaphin protein DUF3391 PF11871.3 EIE81173.1 - 0.08 13.1 1.3 0.1 12.7 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) DUF1319 PF07028.6 EIE81173.1 - 0.081 13.1 1.3 0.11 12.6 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1319) Synaptonemal_3 PF15191.1 EIE81173.1 - 0.082 12.6 0.2 0.14 11.8 0.2 1.4 1 0 0 1 1 1 0 Synaptonemal complex central element protein 3 CENP-F_leu_zip PF10473.4 EIE81173.1 - 0.087 12.6 6.5 0.054 13.3 1.4 1.9 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Sec2p PF06428.6 EIE81173.1 - 0.31 10.9 3.1 0.37 10.6 1.0 1.8 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p DUF2175 PF09943.4 EIE81173.1 - 0.48 10.5 2.0 1.1 9.3 1.3 1.6 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) Nucleoporin2 PF04096.9 EIE81174.1 - 5.2e-46 155.9 0.0 7.8e-46 155.3 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 EIE81174.1 - 4.4e-10 39.7 320.8 0.022 14.9 31.9 8.2 2 2 3 5 5 5 3 Nucleoporin FG repeat region CPSase_L_D2 PF02786.12 EIE81176.1 - 2.7e-107 356.8 0.1 2.7e-83 278.4 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 EIE81176.1 - 1.4e-38 131.4 0.0 1.3e-18 67.1 0.0 2.8 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain CPSase_L_D3 PF02787.14 EIE81176.1 - 9e-37 125.5 0.0 2e-36 124.4 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 EIE81176.1 - 1.3e-32 113.0 0.2 5.1e-17 62.1 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 EIE81176.1 - 1.9e-19 69.5 0.0 3.1e-07 29.4 0.0 4.4 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EIE81176.1 - 5.6e-15 55.1 0.0 1.2e-06 27.9 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EIE81176.1 - 6.4e-12 45.2 0.2 0.00013 21.4 0.0 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.6 EIE81176.1 - 3.3e-08 33.2 0.0 4e-05 23.1 0.0 2.6 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_5 PF13549.1 EIE81176.1 - 3.5e-05 23.1 0.0 0.0021 17.3 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.14 EIE81176.1 - 0.0042 16.6 0.1 3.5 7.1 0.0 2.7 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain TrkA_N PF02254.13 EIE81176.1 - 0.0083 16.1 0.0 0.47 10.4 0.0 3.3 3 0 0 3 3 3 1 TrkA-N domain MGS PF02142.17 EIE81176.1 - 0.017 15.0 0.0 0.12 12.3 0.0 2.4 2 1 1 3 3 3 0 MGS-like domain ATP-grasp_2 PF08442.5 EIE81176.1 - 0.06 12.7 0.0 0.65 9.3 0.0 2.4 2 0 0 2 2 2 0 ATP-grasp domain EMP24_GP25L PF01105.19 EIE81177.1 - 1.3e-15 57.6 1.1 3.7e-14 52.8 0.7 2.1 1 1 0 1 1 1 1 emp24/gp25L/p24 family/GOLD eIF-3c_N PF05470.7 EIE81178.1 - 3e-181 603.5 30.6 4.1e-180 599.8 21.2 2.1 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 EIE81178.1 - 2.1e-15 56.9 0.1 8.3e-15 54.9 0.0 2.2 2 0 0 2 2 2 1 PCI domain DUF3441 PF11923.3 EIE81179.1 - 4.4e-30 103.5 0.1 4.4e-30 103.5 0.1 3.7 2 1 1 3 3 3 1 Domain of unknown function (DUF3441) FbpA PF05833.6 EIE81179.1 - 6.1e-28 97.5 30.9 7.4e-28 97.2 19.9 3.6 2 2 1 3 3 3 2 Fibronectin-binding protein A N-terminus (FbpA) DUF814 PF05670.8 EIE81179.1 - 5.6e-24 83.8 0.0 1.7e-23 82.2 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF814) Aconitase PF00330.15 EIE81180.1 - 4.4e-177 589.2 0.2 1.1e-176 587.9 0.2 1.6 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EIE81180.1 - 5.7e-45 152.6 0.0 1.1e-44 151.7 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Peptidase_C12 PF01088.16 EIE81182.1 - 2.5e-05 23.5 0.0 7.1e-05 22.0 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Alg6_Alg8 PF03155.10 EIE81183.1 - 1.1e-141 472.8 27.6 1.4e-141 472.5 19.1 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family ketoacyl-synt PF00109.21 EIE81183.1 - 2.4e-14 53.4 0.0 3e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EIE81184.1 - 5.1e-37 126.3 0.2 8.4e-37 125.6 0.2 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.21 EIE81184.1 - 1.6e-29 103.2 3.6 2.1e-29 102.7 0.7 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Thiolase_N PF00108.18 EIE81184.1 - 2.6e-05 23.3 0.0 5.2e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EIE81184.1 - 0.0017 17.7 2.3 0.014 14.8 0.1 2.8 2 1 1 3 3 3 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 EIE81184.1 - 0.038 13.6 0.2 1.2 8.8 0.0 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III STAS PF01740.16 EIE81184.1 - 0.11 11.8 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 STAS domain NIPSNAP PF07978.8 EIE81185.1 - 1.6e-13 50.4 0.1 9.1e-10 38.4 0.0 2.2 2 0 0 2 2 2 2 NIPSNAP Dna2 PF08696.6 EIE81185.1 - 0.1 11.8 0.4 2.9 7.1 0.1 2.1 1 1 1 2 2 2 0 DNA replication factor Dna2 DUF3336 PF11815.3 EIE81186.1 - 6.7e-21 74.3 0.4 1.3e-20 73.3 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EIE81186.1 - 1.3e-19 70.9 0.0 3.3e-19 69.6 0.0 1.7 1 1 0 1 1 1 1 Patatin-like phospholipase Ank_2 PF12796.2 EIE81187.1 - 5.4e-28 97.1 0.5 1.2e-13 51.1 0.2 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EIE81187.1 - 1e-23 81.8 5.7 7.4e-08 31.8 0.0 6.2 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.1 EIE81187.1 - 8e-19 65.8 4.3 1.8e-05 24.5 0.0 5.9 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 EIE81187.1 - 2.1e-16 59.9 1.4 5.7e-06 26.7 0.0 4.2 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EIE81187.1 - 3.4e-14 52.5 8.2 8.5e-05 22.6 0.0 5.3 1 1 4 5 5 5 4 Ankyrin repeats (many copies) DUF1436 PF07262.6 EIE81187.1 - 0.0037 16.7 0.4 3 7.3 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1436) SR-25 PF10500.4 EIE81187.1 - 8.4 5.7 10.1 0.19 11.1 2.1 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Pkinase PF00069.20 EIE81190.1 - 2.8e-52 177.4 0.2 9.4e-52 175.7 0.2 2.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE81190.1 - 8.6e-33 113.4 0.1 1.6e-32 112.5 0.1 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE81190.1 - 1.5e-05 24.1 0.0 2.9e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EIE81190.1 - 0.00097 18.2 0.4 0.002 17.2 0.3 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIE81190.1 - 0.078 12.7 0.9 1.8 8.2 0.5 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pro_isomerase PF00160.16 EIE81191.1 - 2.1e-18 66.9 0.0 2.7e-18 66.6 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PLDc_N PF13396.1 EIE81191.1 - 9.2e-11 41.2 4.6 1.5e-10 40.5 3.2 1.4 1 0 0 1 1 1 1 Phospholipase_D-nuclease N-terminal NfeD PF01957.13 EIE81191.1 - 0.057 13.5 0.4 0.081 13.0 0.3 1.2 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding DUF4234 PF14018.1 EIE81191.1 - 0.37 10.5 1.9 0.71 9.6 1.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4234) IF4E PF01652.13 EIE81193.1 - 1.6e-57 193.6 0.3 1.8e-57 193.4 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E WD40 PF00400.27 EIE81194.1 - 6.1e-42 140.0 12.1 3.4e-08 33.0 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat eIF2A PF08662.6 EIE81194.1 - 1.9e-06 27.7 0.7 3.7e-05 23.5 0.1 2.5 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A HIRA_B PF09453.5 EIE81194.1 - 0.00013 21.4 0.5 0.00038 19.9 0.3 1.9 1 0 0 1 1 1 1 HIRA B motif PSII_BNR PF14870.1 EIE81194.1 - 0.01 14.8 0.3 0.021 13.8 0.1 1.6 2 0 0 2 2 2 0 Photosynthesis system II assembly factor YCF48 AP2 PF00847.15 EIE81194.1 - 0.048 13.8 0.5 5 7.3 0.0 2.6 2 0 0 2 2 2 0 AP2 domain PD40 PF07676.7 EIE81194.1 - 0.053 13.2 0.1 4.9 6.9 0.0 3.7 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Coatomer_WDAD PF04053.9 EIE81194.1 - 0.097 11.4 0.4 0.42 9.3 0.1 2.0 2 1 0 2 2 2 0 Coatomer WD associated region MAPEG PF01124.13 EIE81195.1 - 1.6e-06 27.7 1.8 3e-06 26.8 1.2 1.5 1 1 0 1 1 1 1 MAPEG family DUF1180 PF06679.7 EIE81195.1 - 0.035 13.9 0.0 0.052 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) CAP_N PF01213.14 EIE81195.1 - 0.053 12.8 2.4 0.071 12.3 1.6 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal START PF01852.14 EIE81196.1 - 1.8e-13 50.2 0.0 2.1e-13 50.0 0.0 1.0 1 0 0 1 1 1 1 START domain SNF2_N PF00176.18 EIE81197.1 - 6.3e-76 255.0 0.2 9e-76 254.5 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EIE81197.1 - 1.7e-14 53.3 0.0 9.4e-14 51.0 0.0 2.3 3 0 0 3 3 2 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.1 EIE81197.1 - 1.6e-07 30.8 8.3 3.9e-07 29.6 5.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.24 EIE81197.1 - 1.6e-07 30.9 0.0 4.2e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4_2 PF13923.1 EIE81197.1 - 6.1e-07 29.3 10.9 6.1e-07 29.3 7.5 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIE81197.1 - 5.7e-06 25.8 10.6 1.2e-05 24.8 7.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIE81197.1 - 3.4e-05 23.5 10.7 9.1e-05 22.2 7.4 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 EIE81197.1 - 0.00013 21.7 10.5 0.00032 20.5 7.3 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.1 EIE81197.1 - 0.00063 19.2 4.5 0.0022 17.5 3.1 1.9 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.1 EIE81197.1 - 0.00091 18.9 4.3 0.0025 17.5 3.0 1.8 1 0 0 1 1 1 1 RING-type zinc-finger HDA2-3 PF11496.3 EIE81197.1 - 0.0013 17.6 2.0 0.0062 15.3 0.1 2.6 3 1 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 zf-RING_5 PF14634.1 EIE81197.1 - 0.0018 17.9 9.1 0.0043 16.7 6.3 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 EIE81197.1 - 0.43 10.2 10.7 1 9.0 7.4 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Chromo PF00385.19 EIE81198.1 - 1e-09 37.9 0.4 2.1e-09 36.8 0.3 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.21 EIE81198.1 - 1.5e-08 34.7 0.0 2.8e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Tudor-knot PF11717.3 EIE81198.1 - 0.015 14.9 0.9 0.028 14.1 0.1 1.9 2 0 0 2 2 2 0 RNA binding activity-knot of a chromodomain SRP72 PF08492.7 EIE81198.1 - 0.7 10.3 6.6 0.49 10.8 1.9 2.3 2 0 0 2 2 2 0 SRP72 RNA-binding domain DDE_3 PF13358.1 EIE81199.1 - 5e-17 62.0 0.0 7.2e-17 61.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE81199.1 - 1e-09 38.3 2.1 5e-09 36.0 0.9 2.2 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.1 EIE81199.1 - 0.00043 19.8 0.0 0.0011 18.5 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_11 PF08279.7 EIE81199.1 - 0.00068 19.2 0.0 0.0019 17.8 0.0 1.7 1 0 0 1 1 1 1 HTH domain HTH_IclR PF09339.5 EIE81199.1 - 0.00075 19.0 0.0 0.0015 18.0 0.0 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_32 PF13565.1 EIE81199.1 - 0.0046 17.7 0.8 3.2 8.6 0.0 2.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_38 PF13936.1 EIE81199.1 - 0.0073 15.8 0.0 0.016 14.7 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_36 PF13730.1 EIE81199.1 - 0.0082 16.2 0.4 0.25 11.5 0.0 2.9 3 0 0 3 3 3 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.7 EIE81199.1 - 0.011 15.1 0.0 0.03 13.7 0.0 1.7 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_AsnC-type PF13404.1 EIE81199.1 - 0.015 14.8 0.0 0.032 13.7 0.0 1.5 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_Tnp_4 PF13613.1 EIE81199.1 - 0.02 14.4 0.0 0.3 10.6 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix of DDE superfamily endonuclease HTH_7 PF02796.10 EIE81199.1 - 0.025 14.4 0.0 0.061 13.1 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_29 PF13551.1 EIE81199.1 - 0.034 14.2 0.1 0.22 11.6 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn helix UPF0122 PF04297.9 EIE81199.1 - 0.04 13.9 0.2 0.11 12.5 0.0 1.7 2 0 0 2 2 2 0 Putative helix-turn-helix protein, YlxM / p13 like Sigma70_r4 PF04545.11 EIE81199.1 - 0.041 13.2 0.0 0.087 12.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_24 PF13412.1 EIE81199.1 - 0.042 13.2 0.0 0.095 12.1 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_17 PF12728.2 EIE81199.1 - 0.058 13.6 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain GerE PF00196.14 EIE81199.1 - 0.098 11.9 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family HTH_38 PF13936.1 EIE81200.1 - 3.9e-05 23.1 0.1 9.3e-05 21.9 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.1 EIE81200.1 - 0.00095 18.7 0.6 0.0012 18.4 0.0 1.5 2 0 0 2 2 1 1 Homeodomain-like domain Sigma54_DBD PF04552.8 EIE81200.1 - 0.0091 15.5 0.1 0.019 14.4 0.0 1.6 1 1 1 2 2 2 1 Sigma-54, DNA binding domain MarR PF01047.17 EIE81200.1 - 0.01 15.5 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 0 MarR family GcrA PF07750.6 EIE81200.1 - 0.013 15.6 0.1 0.014 15.5 0.0 1.1 1 0 0 1 1 1 0 GcrA cell cycle regulator Fe_dep_repress PF01325.14 EIE81200.1 - 0.018 14.9 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain Phage_CII PF05269.6 EIE81200.1 - 0.027 14.4 0.0 0.033 14.1 0.0 1.3 1 1 0 1 1 1 0 Bacteriophage CII protein CENP-B_N PF04218.8 EIE81200.1 - 0.027 13.8 0.0 0.055 12.8 0.0 1.5 2 0 0 2 2 1 0 CENP-B N-terminal DNA-binding domain HTH_Tnp_4 PF13613.1 EIE81200.1 - 0.031 13.8 0.1 0.047 13.2 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_28 PF13518.1 EIE81200.1 - 0.032 14.2 0.2 0.053 13.5 0.0 1.5 2 0 0 2 2 1 0 Helix-turn-helix domain HTH_6 PF01418.12 EIE81200.1 - 0.036 13.7 0.0 0.055 13.2 0.0 1.5 1 1 0 1 1 1 0 Helix-turn-helix domain, rpiR family TetR_N PF00440.18 EIE81200.1 - 0.037 13.6 0.1 0.066 12.8 0.1 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family LacI PF00356.16 EIE81200.1 - 0.041 13.4 0.0 0.073 12.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family Sigma70_r4_2 PF08281.7 EIE81200.1 - 0.045 13.2 0.1 0.072 12.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_5 PF01022.15 EIE81200.1 - 0.047 13.3 0.0 0.077 12.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_Tnp_1 PF01527.15 EIE81200.1 - 0.048 13.6 0.2 0.07 13.0 0.1 1.5 1 1 0 1 1 1 0 Transposase TrmB PF01978.14 EIE81200.1 - 0.049 13.3 0.0 0.082 12.6 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_3 PF01381.17 EIE81200.1 - 0.056 13.2 0.1 0.092 12.6 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix Terminase_5 PF06056.7 EIE81200.1 - 0.057 12.9 0.1 0.1 12.1 0.0 1.6 1 1 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) HTH_Tnp_IS630 PF01710.11 EIE81200.1 - 0.07 12.8 0.1 0.08 12.6 0.1 1.1 1 0 0 1 1 1 0 Transposase GerE PF00196.14 EIE81200.1 - 0.11 11.8 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family HTH_11 PF08279.7 EIE81200.1 - 0.12 12.0 0.1 0.19 11.4 0.0 1.5 1 1 0 1 1 1 0 HTH domain HTH_AsnC-type PF13404.1 EIE81200.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_10 PF04967.7 EIE81200.1 - 0.13 11.8 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 HTH DNA binding domain HTH_IclR PF09339.5 EIE81200.1 - 0.14 11.7 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 IclR helix-turn-helix domain DUF3862 PF12978.2 EIE81201.1 - 0.047 13.3 0.2 0.066 12.8 0.2 1.1 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3862) Lipoprotein_5 PF01298.13 EIE81201.1 - 0.055 12.4 0.0 0.059 12.3 0.0 1.0 1 0 0 1 1 1 0 Transferrin binding protein-like solute binding protein DUF3708 PF12501.3 EIE81201.1 - 0.064 13.0 2.0 0.087 12.6 1.4 1.1 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter APC_CDC26 PF10471.4 EIE81201.1 - 0.52 11.0 8.0 0.94 10.2 5.5 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 Transposase_21 PF02992.9 EIE81203.1 - 2.5e-21 75.8 0.0 5.1e-21 74.8 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 DUF1258 PF06869.7 EIE81203.1 - 0.0031 16.6 0.0 0.0054 15.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) DUF1203 PF06718.6 EIE81205.1 - 0.082 12.7 0.0 0.2 11.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1203) Transposase_21 PF02992.9 EIE81206.1 - 1.4e-21 76.5 0.5 3.4e-21 75.4 0.0 1.7 2 0 0 2 2 2 1 Transposase family tnp2 DUF1258 PF06869.7 EIE81206.1 - 0.004 16.2 0.0 0.0077 15.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) 3HCDH_N PF02737.13 EIE81206.1 - 0.013 15.1 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Rep_fac_C PF08542.6 EIE81206.1 - 0.1 12.5 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 Replication factor C C-terminal domain Epsilon_antitox PF08998.6 EIE81206.1 - 0.39 10.7 4.4 0.39 10.7 0.3 2.5 3 0 0 3 3 3 0 Bacterial epsilon antitoxin DUF1759 PF03564.10 EIE81207.1 - 0.00049 19.9 0.2 0.0011 18.8 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) Asp_protease PF09668.5 EIE81208.1 - 1.5e-09 37.4 0.0 2.7e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 EIE81208.1 - 4.6e-06 27.0 0.0 9.5e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 EIE81208.1 - 6.3e-06 26.0 0.1 3.1e-05 23.8 0.1 2.2 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.6 EIE81208.1 - 0.00021 21.2 0.0 0.00054 19.9 0.0 1.6 2 0 0 2 2 2 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EIE81208.1 - 0.00075 19.2 0.0 0.0016 18.1 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DDE_3 PF13358.1 EIE81210.1 - 2.8e-20 72.5 0.1 5.3e-20 71.6 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE81210.1 - 6e-16 58.2 1.7 2.1e-15 56.4 0.3 2.4 3 0 0 3 3 2 1 Transposase HTH_29 PF13551.1 EIE81210.1 - 1.9e-06 27.9 0.3 6.3e-06 26.3 0.2 1.9 2 0 0 2 2 1 1 Winged helix-turn helix HTH_38 PF13936.1 EIE81210.1 - 9.1e-06 25.1 0.1 2.6e-05 23.6 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_32 PF13565.1 EIE81210.1 - 3.3e-05 24.5 2.3 0.015 16.0 0.1 3.7 4 0 0 4 4 3 1 Homeodomain-like domain HTH_23 PF13384.1 EIE81210.1 - 5.3e-05 22.7 0.1 0.0022 17.5 0.0 2.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.1 EIE81210.1 - 0.00093 19.1 0.0 0.0044 16.9 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.7 EIE81210.1 - 0.0011 18.3 0.5 0.019 14.3 0.0 2.5 3 0 0 3 3 3 1 Sigma-70, region 4 HTH_7 PF02796.10 EIE81210.1 - 0.0014 18.4 1.1 0.084 12.7 0.0 2.8 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase HTH_21 PF13276.1 EIE81210.1 - 0.0018 18.2 0.8 0.11 12.5 0.0 2.7 3 0 0 3 3 2 1 HTH-like domain rve PF00665.21 EIE81210.1 - 0.0042 17.1 0.0 0.014 15.5 0.0 2.0 2 1 0 2 2 2 1 Integrase core domain LacI PF00356.16 EIE81210.1 - 0.011 15.2 1.7 2.3 7.8 0.2 2.7 3 0 0 3 3 3 0 Bacterial regulatory proteins, lacI family HTH_Tnp_4 PF13613.1 EIE81210.1 - 0.017 14.6 0.1 0.046 13.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_36 PF13730.1 EIE81210.1 - 0.042 13.9 0.3 3.3 7.9 0.0 3.0 3 0 0 3 3 3 0 Helix-turn-helix domain CPSase_L_D3 PF02787.14 EIE81210.1 - 0.044 13.5 0.0 0.11 12.2 0.0 1.7 2 0 0 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain HTH_Tnp_ISL3 PF13542.1 EIE81210.1 - 0.1 11.8 2.5 6.9 5.9 0.0 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 UPF0122 PF04297.9 EIE81210.1 - 0.12 12.4 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like Sigma70_r4 PF04545.11 EIE81210.1 - 0.16 11.3 0.4 0.63 9.3 0.0 2.2 3 0 0 3 3 3 0 Sigma-70, region 4 HTH_17 PF12728.2 EIE81210.1 - 0.44 10.8 2.8 12 6.2 0.1 2.7 3 0 0 3 3 2 0 Helix-turn-helix domain DDE_3 PF13358.1 EIE81211.1 - 1e-18 67.4 0.1 3.5e-18 65.7 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE81211.1 - 1.2e-10 41.3 0.3 2.5e-10 40.2 0.2 1.6 1 0 0 1 1 1 1 Transposase rve PF00665.21 EIE81213.1 - 3.7e-17 62.5 0.0 3.2e-16 59.5 0.0 2.4 3 0 0 3 3 3 1 Integrase core domain Chromo PF00385.19 EIE81213.1 - 4.4e-06 26.2 0.2 1.1e-05 25.0 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain YcgR_2 PF12945.2 EIE81213.1 - 0.004 17.0 0.0 0.0086 15.9 0.0 1.6 1 0 0 1 1 1 1 Flagellar protein YcgR Tudor-knot PF11717.3 EIE81213.1 - 0.028 14.1 0.5 0.06 13.0 0.3 1.5 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain RVT_1 PF00078.22 EIE81214.1 - 2.8e-12 46.4 0.5 7e-12 45.1 0.3 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP PF00077.15 EIE81214.1 - 5.9e-08 32.5 0.4 2.2e-07 30.7 0.1 2.2 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 EIE81214.1 - 4.5e-06 27.0 0.7 1.3e-05 25.5 0.2 2.0 2 0 0 2 2 2 1 Aspartyl protease DDE_3 PF13358.1 EIE81215.1 - 2.3e-15 56.6 0.0 2.8e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EIE81216.1 - 1.8e-18 66.6 0.1 3.4e-18 65.7 0.1 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE81216.1 - 1.6e-09 37.7 1.1 4e-09 36.4 0.8 1.7 1 0 0 1 1 1 1 Transposase HTH_Tnp_4 PF13613.1 EIE81216.1 - 0.0051 16.3 0.0 0.01 15.3 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease FAM70 PF14967.1 EIE81216.1 - 0.074 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 FAM70 protein HTH_23 PF13384.1 EIE81216.1 - 0.082 12.5 0.0 0.22 11.2 0.0 1.7 1 0 0 1 1 1 0 Homeodomain-like domain DDE_3 PF13358.1 EIE81217.1 - 7.8e-15 54.8 0.3 9.5e-15 54.6 0.2 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE81217.1 - 0.00068 19.7 0.2 0.0026 17.8 0.0 1.9 1 1 1 2 2 2 1 Integrase core domain HTH_Tnp_Tc3_2 PF01498.13 EIE81218.1 - 8.5e-07 28.9 1.2 6e-06 26.2 0.1 2.3 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.1 EIE81218.1 - 0.0016 18.0 0.1 0.006 16.1 0.1 2.0 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.1 EIE81218.1 - 0.006 15.7 0.2 0.013 14.6 0.2 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_32 PF13565.1 EIE81218.1 - 0.022 15.5 0.6 21 5.9 0.1 3.1 1 1 2 3 3 3 0 Homeodomain-like domain HTH_11 PF08279.7 EIE81218.1 - 0.032 13.8 0.0 0.074 12.7 0.0 1.6 1 0 0 1 1 1 0 HTH domain HTH_28 PF13518.1 EIE81218.1 - 0.045 13.7 0.0 0.097 12.6 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4_2 PF08281.7 EIE81218.1 - 0.1 12.0 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_29 PF13551.1 EIE81218.1 - 0.12 12.5 0.1 0.34 11.0 0.1 1.9 1 1 1 2 2 2 0 Winged helix-turn helix HTH_36 PF13730.1 EIE81218.1 - 1.4 9.1 3.8 2.4 8.3 0.0 2.7 2 1 0 2 2 2 0 Helix-turn-helix domain Mod_r PF07200.8 EIE81219.1 - 0.00027 20.8 0.1 0.00051 19.9 0.1 1.4 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Matrilin_ccoil PF10393.4 EIE81219.1 - 0.023 14.0 0.2 0.05 12.9 0.2 1.5 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin Reo_sigmaC PF04582.7 EIE81219.1 - 0.068 12.3 1.1 0.1 11.7 0.8 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein TMF_DNA_bd PF12329.3 EIE81219.1 - 0.14 11.9 4.0 1.5 8.6 1.4 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding RVT_1 PF00078.22 EIE81220.1 - 1.1e-28 100.1 0.0 1.7e-28 99.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EIE81220.1 - 1.6e-18 66.4 0.0 3.4e-18 65.3 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EIE81220.1 - 5e-05 23.3 0.0 0.00018 21.5 0.0 2.0 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Mod_r PF07200.8 EIE81221.1 - 0.023 14.5 0.1 0.043 13.7 0.1 1.4 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Med9 PF07544.8 EIE81221.1 - 0.053 13.2 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Matrilin_ccoil PF10393.4 EIE81221.1 - 0.066 12.5 0.3 0.14 11.5 0.2 1.5 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin Reo_sigmaC PF04582.7 EIE81221.1 - 0.074 12.2 0.4 0.11 11.5 0.3 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF904 PF06005.7 EIE81221.1 - 0.18 12.1 2.2 0.6 10.4 1.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF904) DivIC PF04977.10 EIE81221.1 - 0.2 11.1 0.8 0.41 10.1 0.5 1.5 1 0 0 1 1 1 0 Septum formation initiator RVT_1 PF00078.22 EIE81222.1 - 7.2e-29 100.6 0.0 1.1e-28 100.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EIE81222.1 - 1.5e-18 66.5 0.0 3.1e-18 65.4 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EIE81222.1 - 5.3e-05 23.2 0.0 0.00017 21.6 0.0 1.8 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DDE_Tnp_IS1595 PF12762.2 EIE81223.1 - 1e-21 77.3 0.5 1.9e-21 76.4 0.3 1.4 1 0 0 1 1 1 1 ISXO2-like transposase domain DDE_Tnp_IS1595 PF12762.2 EIE81224.1 - 6.7e-07 29.2 0.1 7.5e-07 29.1 0.1 1.0 1 0 0 1 1 1 1 ISXO2-like transposase domain MRP-L27 PF09809.4 EIE81224.1 - 0.11 12.1 0.1 0.14 11.7 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L27 DDE_Tnp_IS1595 PF12762.2 EIE81225.1 - 1e-17 64.3 0.0 1.4e-17 63.9 0.0 1.1 1 0 0 1 1 1 1 ISXO2-like transposase domain DDE_Tnp_IS66 PF03050.9 EIE81225.1 - 0.15 11.2 0.0 0.17 11.0 0.0 1.1 1 0 0 1 1 1 0 Transposase IS66 family HTH_Tnp_Tc3_2 PF01498.13 EIE81227.1 - 2.8e-08 33.7 0.2 2.8e-08 33.7 0.1 2.1 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 EIE81227.1 - 0.029 14.5 1.2 0.08 13.0 0.8 1.8 1 1 0 1 1 1 0 Winged helix-turn helix HTH_12 PF08461.5 EIE81227.1 - 0.055 13.1 0.1 0.16 11.7 0.1 1.7 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain HTH_21 PF13276.1 EIE81227.1 - 0.058 13.4 1.1 0.5 10.4 0.0 2.3 2 0 0 2 2 2 0 HTH-like domain HTH_Tnp_ISL3 PF13542.1 EIE81227.1 - 0.077 12.1 0.6 0.51 9.5 0.1 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_32 PF13565.1 EIE81227.1 - 0.12 13.1 1.5 0.26 12.1 0.5 1.9 2 0 0 2 2 2 0 Homeodomain-like domain DDE_3 PF13358.1 EIE81228.1 - 3.1e-13 49.6 0.2 4.1e-13 49.3 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE81228.1 - 0.029 14.4 0.0 0.042 13.9 0.0 1.3 1 0 0 1 1 1 0 Integrase core domain DUF1033 PF06279.6 EIE81228.1 - 0.049 13.4 0.8 0.077 12.8 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1033) Myb_DNA-bind_5 PF13873.1 EIE81228.1 - 0.13 12.1 0.5 11 6.0 0.2 2.5 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain DDE_3 PF13358.1 EIE81229.1 - 3.5e-20 72.2 0.1 7.2e-20 71.2 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE81229.1 - 2e-07 30.9 1.4 2e-07 30.9 1.0 2.3 1 1 1 2 2 2 1 Transposase rve PF00665.21 EIE81229.1 - 0.037 14.1 0.1 0.089 12.8 0.0 1.9 1 1 0 1 1 1 0 Integrase core domain HTH_12 PF08461.5 EIE81229.1 - 0.086 12.5 0.1 0.28 10.9 0.0 1.8 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain HTH_29 PF13551.1 EIE81229.1 - 0.21 11.7 2.9 0.19 11.8 0.8 1.9 2 0 0 2 2 2 0 Winged helix-turn helix DUF1033 PF06279.6 EIE81229.1 - 0.36 10.6 0.0 0.36 10.6 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1033) NFRKB_winged PF14465.1 EIE81229.1 - 0.37 10.6 3.4 5.5 6.8 0.4 2.9 2 1 0 2 2 2 0 NFRKB Winged Helix-like HTH_32 PF13565.1 EIE81229.1 - 0.96 10.2 7.5 0.19 12.5 1.1 2.7 4 0 0 4 4 4 0 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.1 EIE81229.1 - 1.6 7.9 3.7 1.1 8.5 0.1 2.4 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 DDE_3 PF13358.1 EIE81230.1 - 2.7e-15 56.3 0.1 3.6e-15 55.9 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Cas_Csx9 PF09658.5 EIE81230.1 - 0.15 10.8 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csx9) HTH_Tnp_Tc3_2 PF01498.13 EIE81231.1 - 1e-06 28.6 0.4 1e-06 28.6 0.3 1.9 2 0 0 2 2 2 1 Transposase Sigma70_r1_2 PF00140.15 EIE81231.1 - 0.027 14.1 0.0 0.05 13.2 0.0 1.4 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 Trp_repressor PF01371.14 EIE81231.1 - 0.12 12.3 0.1 0.22 11.4 0.1 1.5 1 0 0 1 1 1 0 Trp repressor protein Plant_tran PF04827.9 EIE81232.1 - 6.5e-103 342.4 0.0 1.1e-102 341.7 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_4 PF13359.1 EIE81232.1 - 1e-15 57.7 0.0 1.6e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Myb_DNA-bind_4 PF13837.1 EIE81233.1 - 2.8e-05 24.1 0.6 3.4e-05 23.8 0.4 1.1 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 EIE81233.1 - 0.00066 19.5 1.8 0.0012 18.6 1.2 1.5 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.2 EIE81233.1 - 0.0011 19.6 0.1 0.0012 19.3 0.1 1.1 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DDE_3 PF13358.1 EIE81234.1 - 7.1e-10 38.7 0.0 1.9e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE81234.1 - 1.4e-07 31.4 1.5 3.1e-07 30.3 1.0 1.7 1 0 0 1 1 1 1 Transposase FAM70 PF14967.1 EIE81234.1 - 0.03 13.5 0.0 0.046 12.9 0.0 1.2 1 0 0 1 1 1 0 FAM70 protein DDE_3 PF13358.1 EIE81235.1 - 3.9e-16 59.1 0.0 5.3e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE81235.1 - 0.041 13.9 1.2 0.14 12.2 0.5 2.2 3 0 0 3 3 3 0 Transposase DDE_3 PF13358.1 EIE81240.1 - 7.3e-25 87.4 0.0 9.3e-25 87.0 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE81240.1 - 0.00019 21.5 0.0 0.00036 20.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain DDE_3 PF13358.1 EIE81241.1 - 3.2e-05 23.7 0.0 5.1e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE81241.1 - 0.00051 20.0 1.1 0.0015 18.5 0.2 2.1 2 0 0 2 2 2 1 Transposase HTH_Tnp_Tc3_2 PF01498.13 EIE81244.1 - 6.1e-06 26.1 0.2 1.3e-05 25.1 0.1 1.6 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.1 EIE81245.1 - 1.5e-09 37.7 0.3 1.8e-09 37.5 0.2 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease NUDIX_4 PF14815.1 EIE81245.1 - 0.11 11.8 0.7 0.16 11.4 0.5 1.3 1 0 0 1 1 1 0 NUDIX domain TBPIP PF07106.8 EIE81246.1 - 0.021 14.3 1.7 0.71 9.4 1.1 2.5 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) FtsK_SpoIIIE PF01580.13 EIE81246.1 - 0.063 12.7 0.1 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family TMF_DNA_bd PF12329.3 EIE81246.1 - 0.072 12.8 2.6 0.28 11.0 1.8 2.0 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding YPEB PF14620.1 EIE81246.1 - 0.079 11.9 2.6 0.12 11.4 1.8 1.2 1 0 0 1 1 1 0 YpeB sporulation CENP-F_leu_zip PF10473.4 EIE81246.1 - 0.11 12.2 4.2 0.22 11.3 0.9 2.5 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2296 PF10058.4 EIE81246.1 - 0.15 11.8 1.5 0.36 10.6 1.0 1.6 1 0 0 1 1 1 0 Predicted integral membrane metal-binding protein (DUF2296) DUF2730 PF10805.3 EIE81246.1 - 0.16 11.7 1.1 0.8 9.4 0.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) TMF_TATA_bd PF12325.3 EIE81246.1 - 0.2 11.4 5.4 0.11 12.2 0.8 2.4 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding IncA PF04156.9 EIE81246.1 - 0.5 9.9 5.7 0.39 10.2 2.3 2.1 2 1 0 2 2 2 0 IncA protein BRICHOS PF04089.9 EIE81246.1 - 0.77 9.6 4.7 0.17 11.7 0.2 2.3 3 1 0 3 3 3 0 BRICHOS domain Ima1_N PF09779.4 EIE81246.1 - 0.9 10.0 5.6 9.7 6.7 3.9 2.7 1 1 0 1 1 1 0 Ima1 N-terminal domain DUF4407 PF14362.1 EIE81246.1 - 1 8.2 5.0 2 7.2 3.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TEX13 PF15186.1 EIE81246.1 - 4.4 6.8 8.2 0.13 11.8 0.7 2.1 3 0 0 3 3 3 0 Testis-expressed sequence 13 protein family ADK_lid PF05191.9 EIE81246.1 - 7 6.4 6.5 9.4 6.0 0.3 2.2 1 1 1 2 2 2 0 Adenylate kinase, active site lid Exo_endo_phos_2 PF14529.1 EIE81247.1 - 2e-14 53.2 0.0 6.3e-14 51.6 0.0 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EIE81247.1 - 4.8e-06 26.7 0.0 1.7e-05 24.8 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family FlxA PF14282.1 EIE81247.1 - 0.34 10.8 4.7 0.63 10.0 3.3 1.4 1 0 0 1 1 1 0 FlxA-like protein RVT_1 PF00078.22 EIE81248.1 - 6.4e-26 91.0 0.0 1.5e-25 89.7 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_3 PF13358.1 EIE81248.1 - 2.7e-18 66.1 0.0 5.7e-18 65.0 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE81248.1 - 4e-05 23.5 0.7 0.0001 22.3 0.5 1.7 1 0 0 1 1 1 1 Transposase Transposase_21 PF02992.9 EIE81249.1 - 1.8e-21 76.2 0.4 4e-21 75.1 0.0 1.7 2 0 0 2 2 2 1 Transposase family tnp2 DUF1258 PF06869.7 EIE81249.1 - 0.0029 16.7 0.0 0.0056 15.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) 3HCDH_N PF02737.13 EIE81249.1 - 0.016 14.9 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Rep_fac_C PF08542.6 EIE81249.1 - 0.12 12.3 0.0 0.32 11.0 0.0 1.7 1 0 0 1 1 1 0 Replication factor C C-terminal domain Epsilon_antitox PF08998.6 EIE81249.1 - 0.99 9.4 5.1 0.48 10.4 0.3 2.4 2 0 0 2 2 2 0 Bacterial epsilon antitoxin DUF4557 PF15101.1 EIE81250.1 - 6.7 6.4 8.3 11 5.8 5.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) VIT1 PF01988.14 EIE81250.1 - 6.7 6.1 5.7 12 5.2 4.0 1.5 1 1 0 1 1 1 0 VIT family Leader_Erm PF08253.6 EIE81251.1 - 0.33 10.4 0.3 0.33 10.4 0.2 2.1 2 0 0 2 2 2 0 Erm Leader peptide Mto2_bdg PF12808.2 EIE81252.1 - 0.39 10.8 6.6 4.6 7.4 0.2 3.4 3 0 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Transposase_21 PF02992.9 EIE81253.1 - 7.4e-23 80.8 0.1 7.4e-23 80.8 0.1 1.7 2 0 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.1 EIE81253.1 - 1.5e-05 24.4 0.6 3.3e-05 23.3 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) DDE_3 PF13358.1 EIE81254.1 - 1.1e-17 64.1 0.1 2.4e-17 63.0 0.1 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE81254.1 - 6.2e-05 22.9 2.0 0.00012 22.0 1.4 1.5 1 0 0 1 1 1 1 Transposase FAM70 PF14967.1 EIE81254.1 - 0.038 13.2 0.0 0.059 12.5 0.0 1.2 1 0 0 1 1 1 0 FAM70 protein rve PF00665.21 EIE81255.1 - 7.4e-22 77.7 0.0 2.2e-21 76.1 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE81255.1 - 7.3e-16 58.1 0.1 2.2e-15 56.6 0.1 1.9 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE81255.1 - 5.6e-11 41.9 0.3 1.2e-10 40.8 0.2 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.1 EIE81255.1 - 2e-08 34.6 0.0 5e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.12 EIE81255.1 - 5.1e-07 29.6 0.0 1.2e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein gag-asp_proteas PF13975.1 EIE81255.1 - 5.6e-07 29.2 0.0 1.7e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.5 EIE81255.1 - 8e-06 25.4 0.0 1.9e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Viral_NABP PF05515.6 EIE81255.1 - 0.0057 16.9 2.2 0.015 15.5 1.5 1.7 1 0 0 1 1 1 1 Viral nucleic acid binding DDE_3 PF13358.1 EIE81256.1 - 6.1e-18 64.9 0.0 1.4e-17 63.8 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE81256.1 - 3.3e-08 33.4 0.5 1.9e-07 31.0 0.6 2.0 2 0 0 2 2 2 1 Transposase RVT_1 PF00078.22 EIE81257.1 - 1.9e-07 30.6 0.0 8.5e-07 28.5 0.0 1.7 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) A_thal_3526 PF09713.5 EIE81257.1 - 0.087 12.9 0.0 0.21 11.7 0.0 1.6 2 0 0 2 2 2 0 Plant protein 1589 of unknown function (A_thal_3526) rve PF00665.21 EIE81258.1 - 1.9e-19 69.9 0.0 6.5e-19 68.2 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE81258.1 - 3.5e-11 42.8 1.5 1.2e-10 41.1 0.3 2.4 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE81258.1 - 1.3e-07 31.1 0.1 1.3e-07 31.1 0.1 3.4 3 0 0 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain RVP PF00077.15 EIE81258.1 - 0.00057 19.7 0.1 0.0024 17.7 0.1 2.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 EIE81258.1 - 0.035 14.6 0.0 0.093 13.2 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease DUF2501 PF10696.4 EIE81259.1 - 0.043 13.8 0.0 0.087 12.8 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2501) DUF2781 PF10914.3 EIE81260.1 - 9.4e-28 96.8 15.5 4.4e-27 94.7 10.7 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2781) RabGAP-TBC PF00566.13 EIE81261.1 - 2.1e-56 190.7 0.1 2.1e-56 190.7 0.1 2.2 2 1 1 3 3 3 1 Rab-GTPase-TBC domain DUF1311 PF07007.7 EIE81261.1 - 0.016 15.2 11.3 0.1 12.7 4.4 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF1311) DUF2431 PF10354.4 EIE81261.1 - 0.045 13.7 1.6 0.082 12.8 1.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2431) WXG100 PF06013.7 EIE81261.1 - 0.12 12.3 8.8 0.3 11.0 0.7 3.1 1 1 2 3 3 3 0 Proteins of 100 residues with WXG DUF1818 PF08848.6 EIE81261.1 - 0.35 10.9 5.8 0.18 11.9 1.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1818) FCH PF00611.18 EIE81261.1 - 0.88 9.7 9.7 0.24 11.6 1.9 2.9 3 0 0 3 3 3 0 Fes/CIP4, and EFC/F-BAR homology domain DUF972 PF06156.8 EIE81261.1 - 1.7 8.9 16.9 0.42 10.9 1.3 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF972) DUF3287 PF11690.3 EIE81261.1 - 1.9 8.6 10.3 2.8 8.0 1.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3287) DUF4140 PF13600.1 EIE81261.1 - 3 8.3 8.9 3.2 8.2 2.0 2.5 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF904 PF06005.7 EIE81261.1 - 3.3 8.0 17.6 0.15 12.3 4.1 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF904) APG6 PF04111.7 EIE81261.1 - 7.5 5.5 20.3 23 3.8 14.0 1.8 1 1 0 1 1 1 0 Autophagy protein Apg6 GCV_T PF01571.16 EIE81262.1 - 7.8e-53 178.9 1.0 1.2e-33 116.2 0.1 2.0 1 1 1 2 2 2 2 Aminomethyltransferase folate-binding domain SoxG PF04268.7 EIE81262.1 - 0.099 12.4 0.0 6.7 6.5 0.0 2.1 1 1 1 2 2 2 0 Sarcosine oxidase, gamma subunit family Hexokinase_2 PF03727.11 EIE81263.1 - 5.5e-72 241.8 0.0 9.8e-72 241.0 0.0 1.4 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EIE81263.1 - 4.7e-55 186.1 0.1 8.3e-55 185.3 0.1 1.4 1 0 0 1 1 1 1 Hexokinase Oxysterol_BP PF01237.13 EIE81264.1 - 7.1e-49 166.1 0.0 8.3e-49 165.9 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein Troponin PF00992.15 EIE81265.1 - 0.027 14.5 2.4 0.029 14.4 1.7 1.0 1 0 0 1 1 1 0 Troponin ING PF12998.2 EIE81265.1 - 0.11 12.7 2.9 0.13 12.5 2.0 1.1 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding CCDC144C PF14915.1 EIE81265.1 - 0.15 10.9 8.5 0.16 10.8 5.9 1.0 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region DUF2764 PF10962.3 EIE81265.1 - 0.32 10.2 3.2 0.31 10.2 2.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2764) GET2 PF08690.5 EIE81265.1 - 1.4 8.0 6.8 1.5 8.0 4.7 1.0 1 0 0 1 1 1 0 GET complex subunit GET2 ATP_sub_h PF10775.4 EIE81266.1 - 1.8e-17 62.7 1.0 2.5e-17 62.3 0.7 1.2 1 0 0 1 1 1 1 ATP synthase complex subunit h ATP-synt_F6 PF05511.6 EIE81266.1 - 0.0065 16.3 0.1 0.0084 15.9 0.1 1.4 1 1 0 1 1 1 1 Mitochondrial ATP synthase coupling factor 6 SNF5 PF04855.7 EIE81266.1 - 0.095 12.1 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 SNF5 / SMARCB1 / INI1 Pec_lyase_N PF04431.8 EIE81266.1 - 0.12 12.4 0.2 17 5.5 0.0 2.2 2 0 0 2 2 2 0 Pectate lyase, N terminus FAD_binding_3 PF01494.14 EIE81267.1 - 1.9e-19 69.9 0.2 1.7e-08 33.9 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain DAO PF01266.19 EIE81267.1 - 1.2e-06 27.7 0.0 9.9e-05 21.3 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EIE81267.1 - 2.2e-05 24.7 0.0 0.011 16.1 0.0 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIE81267.1 - 3.6e-05 23.7 0.0 9.7e-05 22.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EIE81267.1 - 0.00068 18.6 0.1 0.002 17.0 0.0 1.7 1 1 0 1 1 1 1 Lycopene cyclase protein Amino_oxidase PF01593.19 EIE81267.1 - 0.0009 18.4 0.0 0.49 9.4 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.19 EIE81267.1 - 0.0028 16.5 0.0 0.0052 15.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.9 EIE81267.1 - 0.0042 15.7 0.1 0.35 9.4 0.0 2.2 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox_3 PF13738.1 EIE81267.1 - 0.011 15.8 0.3 0.076 13.0 0.1 2.3 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EIE81267.1 - 0.013 15.3 0.0 0.027 14.3 0.0 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EIE81267.1 - 0.04 13.6 0.4 2.7 7.7 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.12 EIE81267.1 - 0.082 11.9 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.16 EIE81267.1 - 0.1 12.1 0.0 0.21 11.1 0.0 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 EIE81267.1 - 0.11 12.5 0.0 0.33 10.9 0.0 1.9 1 0 0 1 1 1 0 TrkA-N domain CPSase_L_chain PF00289.17 EIE81267.1 - 0.11 12.5 0.0 2.1 8.4 0.0 2.4 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, N-terminal domain Ribosomal_L37ae PF01780.14 EIE81268.1 - 9.3e-41 137.6 10.8 1e-40 137.4 7.5 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.2 EIE81268.1 - 0.00069 19.3 2.2 0.001 18.8 1.5 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain A2L_zn_ribbon PF08792.5 EIE81268.1 - 0.0047 16.3 3.3 0.84 9.1 0.1 2.2 2 0 0 2 2 2 2 A2L zinc ribbon domain zf-FCS PF06467.9 EIE81268.1 - 0.027 14.0 2.2 0.75 9.4 0.1 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-H2C2_2 PF13465.1 EIE81268.1 - 0.08 13.2 1.4 2.5 8.5 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger double domain zf-BED PF02892.10 EIE81268.1 - 0.1 12.3 5.5 0.12 12.1 0.4 2.3 1 1 1 2 2 2 0 BED zinc finger Zn-ribbon_8 PF09723.5 EIE81268.1 - 0.17 11.8 1.7 0.9 9.5 0.1 2.2 2 0 0 2 2 2 0 Zinc ribbon domain Elf1 PF05129.8 EIE81268.1 - 0.27 10.9 2.7 0.5 10.0 1.9 1.5 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like zf-C2H2 PF00096.21 EIE81268.1 - 1.8 9.0 4.1 18 5.8 0.3 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type Tropomyosin_1 PF12718.2 EIE81269.1 - 4.5e-30 104.3 43.0 1.2e-29 102.9 29.8 1.6 1 1 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 EIE81269.1 - 1.5e-06 27.5 42.8 0.0028 16.7 20.1 2.1 1 1 1 2 2 2 2 Tropomyosin GAS PF13851.1 EIE81269.1 - 0.0022 17.2 35.7 0.0029 16.8 24.7 1.3 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding IncA PF04156.9 EIE81269.1 - 0.011 15.2 41.9 0.031 13.8 15.5 2.0 1 1 1 2 2 2 0 IncA protein ADIP PF11559.3 EIE81269.1 - 0.017 15.0 34.3 0.088 12.7 5.1 2.8 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding PspA_IM30 PF04012.7 EIE81269.1 - 0.028 13.7 33.6 0.068 12.5 23.3 1.8 1 1 0 1 1 1 0 PspA/IM30 family Myosin_tail_1 PF01576.14 EIE81269.1 - 0.029 12.1 41.1 0.038 11.7 28.5 1.2 1 0 0 1 1 1 0 Myosin tail APG6 PF04111.7 EIE81269.1 - 0.04 12.9 40.1 0.21 10.5 8.1 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 CENP-F_leu_zip PF10473.4 EIE81269.1 - 0.045 13.6 41.8 0.19 11.6 12.4 2.8 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HOOK PF05622.7 EIE81269.1 - 0.061 11.1 34.4 0.067 11.0 23.9 1.0 1 0 0 1 1 1 0 HOOK protein ATG16 PF08614.6 EIE81269.1 - 0.071 12.9 34.1 0.6 9.9 12.8 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) KLRAQ PF10205.4 EIE81269.1 - 0.084 12.9 26.6 0.12 12.4 5.0 2.2 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein BRE1 PF08647.6 EIE81269.1 - 0.21 11.5 35.9 0.56 10.2 10.5 2.3 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase Laminin_II PF06009.7 EIE81269.1 - 0.23 11.1 25.2 0.56 9.9 8.0 2.6 1 1 1 2 2 2 0 Laminin Domain II TPR_MLP1_2 PF07926.7 EIE81269.1 - 0.26 11.0 38.6 2.6 7.7 26.5 2.3 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein MAD PF05557.8 EIE81269.1 - 0.26 9.3 37.0 0.37 8.8 25.7 1.2 1 0 0 1 1 1 0 Mitotic checkpoint protein Reo_sigmaC PF04582.7 EIE81269.1 - 0.3 10.2 4.9 0.58 9.2 2.7 1.7 1 1 1 2 2 2 0 Reovirus sigma C capsid protein AAA_13 PF13166.1 EIE81269.1 - 0.44 8.9 31.3 0.65 8.3 21.7 1.3 1 0 0 1 1 1 0 AAA domain DUF904 PF06005.7 EIE81269.1 - 0.45 10.8 42.5 0.09 13.0 6.8 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF904) DUF869 PF05911.6 EIE81269.1 - 0.51 8.5 33.2 0.23 9.6 19.3 1.9 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) DUF3450 PF11932.3 EIE81269.1 - 0.55 9.4 28.1 0.92 8.7 8.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) CtIP_N PF10482.4 EIE81269.1 - 0.69 9.7 26.7 0.19 11.4 6.9 2.5 1 1 1 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain TMF_DNA_bd PF12329.3 EIE81269.1 - 0.96 9.2 50.1 4.3 7.2 9.3 3.5 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding Exonuc_VII_L PF02601.10 EIE81269.1 - 1 8.4 20.8 1.4 8.0 14.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Striatin PF08232.7 EIE81269.1 - 1.1 9.5 27.4 1.6 9.0 9.2 2.2 1 1 1 2 2 2 0 Striatin family Lectin_N PF03954.9 EIE81269.1 - 1.7 8.0 11.7 0.19 11.1 3.4 2.4 1 1 2 3 3 3 0 Hepatic lectin, N-terminal domain Nup54 PF13874.1 EIE81269.1 - 2.7 7.6 25.6 2.9 7.5 9.1 2.2 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 DUF4200 PF13863.1 EIE81269.1 - 3.3 7.6 42.6 12 5.8 19.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF3584 PF12128.3 EIE81269.1 - 3.8 4.7 33.9 4.6 4.4 23.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF2968 PF11180.3 EIE81269.1 - 4 6.7 25.6 1.1 8.6 4.6 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF2968) Spc7 PF08317.6 EIE81269.1 - 4.1 5.9 35.2 7.1 5.1 8.1 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein YvrJ PF12841.2 EIE81269.1 - 4.6 6.6 11.9 4.5 6.6 0.3 4.0 3 1 0 4 4 4 0 YvrJ protein family WXG100 PF06013.7 EIE81269.1 - 4.6 7.3 16.1 2.3 8.2 0.9 3.9 2 2 1 3 3 3 0 Proteins of 100 residues with WXG DUF1202 PF06717.6 EIE81269.1 - 4.8 6.3 16.6 18 4.4 11.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1202) V_ATPase_I PF01496.14 EIE81269.1 - 6.4 4.4 28.6 1.1 7.0 10.0 2.0 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family DUF972 PF06156.8 EIE81269.1 - 7.2 7.0 30.3 5.2 7.4 7.4 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF972) DUF2911 PF11138.3 EIE81269.1 - 7.4 6.1 7.0 1.6 8.3 1.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2911) Adeno_PIX PF03955.9 EIE81269.1 - 7.4 7.1 18.4 11 6.6 1.5 2.9 1 1 2 3 3 3 0 Adenovirus hexon-associated protein (IX) DUF1664 PF07889.7 EIE81269.1 - 7.9 6.2 20.8 6.3 6.6 3.7 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.5 EIE81269.1 - 9.3 6.3 21.9 2.6 8.1 7.3 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family EMP24_GP25L PF01105.19 EIE81270.1 - 4.4e-37 127.5 0.3 5.1e-37 127.3 0.2 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD eIF-5a PF01287.15 EIE81271.1 - 0.063 13.2 0.2 0.083 12.8 0.2 1.2 1 0 0 1 1 1 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold DDE_3 PF13358.1 EIE81272.1 - 2.6e-21 75.9 0.1 3.1e-21 75.6 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Carboxyl_trans PF01039.17 EIE81272.1 - 0.099 10.9 0.1 0.12 10.7 0.1 1.0 1 0 0 1 1 1 0 Carboxyl transferase domain Peptidase_M24 PF00557.19 EIE81273.1 - 1.4e-55 188.0 0.0 1.8e-55 187.7 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EIE81273.1 - 3.9e-10 39.2 0.0 6.5e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain CodY PF06018.9 EIE81273.1 - 0.11 11.8 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 CodY GAF-like domain Hid1 PF12722.2 EIE81275.1 - 9.6e-28 96.3 8.5 7.6e-17 60.3 0.3 2.6 1 1 1 2 2 2 2 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 EIE81275.1 - 5.8e-15 54.4 0.0 6.6e-15 54.2 0.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein G-gamma PF00631.17 EIE81275.1 - 0.07 12.8 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 GGL domain Pkinase PF00069.20 EIE81276.1 - 1e-62 211.6 0.0 7.2e-40 136.7 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIE81276.1 - 7.6e-30 103.8 0.0 1.2e-22 80.2 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.19 EIE81276.1 - 1.4e-16 60.4 0.3 3e-16 59.4 0.2 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.1 EIE81276.1 - 0.00017 20.6 0.0 0.0038 16.2 0.0 2.7 3 0 0 3 3 3 1 Kinase-like APH PF01636.18 EIE81276.1 - 0.0034 17.1 0.2 0.0077 15.9 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family PAS_3 PF08447.6 EIE81276.1 - 0.018 15.1 0.0 0.053 13.6 0.0 1.8 1 0 0 1 1 1 0 PAS fold PAS_9 PF13426.1 EIE81276.1 - 0.056 13.8 0.1 0.26 11.6 0.0 2.1 2 0 0 2 2 2 0 PAS domain Ribosomal_L21p PF00829.16 EIE81276.1 - 7.1 6.8 5.4 9.6 6.4 0.1 3.5 4 0 0 4 4 4 0 Ribosomal prokaryotic L21 protein C2 PF00168.25 EIE81277.1 - 1.5e-07 31.1 0.0 2.4e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 C2 domain Peptidase_S8 PF00082.17 EIE81279.1 - 4.9e-45 153.8 13.2 7.1e-45 153.3 9.2 1.2 1 0 0 1 1 1 1 Subtilase family DUF1811 PF08838.5 EIE81279.1 - 0.11 12.4 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1811) Pkinase PF00069.20 EIE81280.1 - 2.5e-43 148.0 0.0 3.4e-27 95.2 0.0 2.6 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIE81280.1 - 6.6e-24 84.3 0.0 2.2e-13 49.8 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EIE81280.1 - 0.0045 15.9 0.0 0.0079 15.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like MFS_1 PF07690.11 EIE81285.1 - 7.2e-22 77.5 45.4 3e-20 72.2 30.3 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Tim44 PF04280.10 EIE81286.1 - 1.1e-32 112.9 0.1 1.1e-32 112.9 0.0 2.2 2 1 0 2 2 2 1 Tim44-like domain Rapamycin_bind PF08771.6 EIE81286.1 - 0.21 11.6 5.8 0.91 9.6 0.9 2.7 1 1 1 2 2 2 0 Rapamycin binding domain PAPS_reduct PF01507.14 EIE81286.1 - 0.44 10.3 6.1 0.059 13.1 1.4 1.6 2 0 0 2 2 2 0 Phosphoadenosine phosphosulfate reductase family CHAD PF05235.9 EIE81286.1 - 0.89 9.0 7.4 2.6 7.5 5.1 1.8 1 1 0 1 1 1 0 CHAD domain Pyr_redox PF00070.22 EIE81287.1 - 2.1e-16 60.1 0.0 6.8e-11 42.4 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EIE81287.1 - 8.4e-14 51.9 0.3 3.6e-11 43.3 0.2 4.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase RGS PF00615.14 EIE81287.1 - 8.3e-13 48.4 0.4 1.8e-12 47.4 0.3 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain DAO PF01266.19 EIE81287.1 - 7.6e-09 34.9 0.0 0.055 12.3 0.0 4.3 3 1 1 4 4 4 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIE81287.1 - 1.4e-07 31.4 0.0 0.013 15.5 0.0 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EIE81287.1 - 7.9e-07 29.3 0.1 0.041 13.9 0.0 3.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EIE81287.1 - 9.4e-05 22.3 0.0 0.057 13.4 0.0 2.7 2 0 0 2 2 2 1 TrkA-N domain Lycopene_cycl PF05834.7 EIE81287.1 - 0.0001 21.3 0.0 0.23 10.3 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_9 PF13454.1 EIE81287.1 - 0.00015 21.5 0.1 7.5 6.3 0.0 3.9 2 2 2 4 4 4 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 EIE81287.1 - 0.0005 19.2 0.0 0.62 9.0 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain RGS-like PF09128.6 EIE81287.1 - 0.00093 18.7 0.3 0.0016 17.9 0.2 1.3 1 0 0 1 1 1 1 Regulator of G protein signalling-like domain K_oxygenase PF13434.1 EIE81287.1 - 0.0011 18.0 0.0 0.19 10.6 0.0 2.6 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.9 EIE81287.1 - 0.009 14.6 0.0 0.053 12.1 0.0 2.0 2 0 0 2 2 2 1 Tryptophan halogenase AlaDh_PNT_C PF01262.16 EIE81287.1 - 0.017 14.6 0.0 0.44 10.0 0.0 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.9 EIE81287.1 - 0.022 14.1 0.2 1.2 8.5 0.0 2.4 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.1 EIE81287.1 - 0.032 14.4 0.0 3 8.1 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding ThiF PF00899.16 EIE81287.1 - 0.12 12.1 0.0 3.7 7.3 0.0 2.5 2 0 0 2 2 2 0 ThiF family E1-E2_ATPase PF00122.15 EIE81288.1 - 1.8e-58 197.2 0.7 1.8e-58 197.2 0.5 3.5 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 EIE81288.1 - 2.3e-21 77.2 0.0 8.7e-21 75.3 0.0 2.1 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EIE81288.1 - 2.7e-12 47.2 0.0 5.5e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EIE81288.1 - 4.3e-12 45.3 0.7 9e-12 44.2 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EIE81288.1 - 0.00023 20.8 1.6 0.00041 19.9 0.1 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EIE81288.1 - 0.012 15.5 0.0 0.025 14.5 0.0 1.5 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit SWIRM PF04433.12 EIE81289.1 - 5.1e-21 74.5 0.0 1.7e-20 72.9 0.0 2.0 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 EIE81289.1 - 6.7e-12 45.2 3.7 1.1e-11 44.5 0.6 2.9 3 0 0 3 3 3 1 Myb-like DNA-binding domain JAB PF01398.16 EIE81289.1 - 2.8e-11 43.1 0.0 2.8e-11 43.1 0.0 3.1 3 2 0 3 3 3 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 EIE81289.1 - 3.1e-07 29.9 0.7 2.1e-06 27.2 0.1 2.4 1 1 1 2 2 2 1 Prokaryotic homologs of the JAB domain Myb_DNA-bind_6 PF13921.1 EIE81289.1 - 1.4e-06 28.3 0.7 1.4e-06 28.3 0.5 3.1 3 0 0 3 3 3 1 Myb-like DNA-binding domain Pkinase PF00069.20 EIE81290.1 - 1.6e-76 256.9 0.0 1.8e-76 256.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE81290.1 - 7.2e-36 123.5 0.0 9.4e-36 123.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE81290.1 - 0.00076 18.5 0.1 0.0017 17.4 0.0 1.6 1 1 1 2 2 2 1 Kinase-like Pkinase PF00069.20 EIE81291.1 - 1.8e-48 164.9 0.0 2.3e-48 164.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE81291.1 - 1.7e-21 76.5 0.0 1.9e-21 76.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE81291.1 - 1.8e-08 33.7 0.0 3.4e-08 32.7 0.0 1.4 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EIE81291.1 - 0.035 13.8 0.1 1.8 8.2 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EIE81291.1 - 0.1 11.4 0.1 0.18 10.5 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 NTR2 PF15458.1 EIE81292.1 - 3.9e-38 131.1 9.7 3.9e-38 131.1 6.7 3.9 4 1 0 4 4 4 1 Nineteen complex-related protein 2 GCFC PF07842.7 EIE81292.1 - 8.5e-12 44.9 0.6 2.8e-11 43.3 0.4 1.9 1 1 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein XAP5 PF04921.9 EIE81292.1 - 0.00029 20.5 2.2 0.00029 20.5 1.5 3.2 3 1 0 3 3 3 1 XAP5, circadian clock regulator Tho2 PF11262.3 EIE81293.1 - 5.2e-59 199.7 2.4 5.2e-59 199.7 1.7 2.0 2 0 0 2 2 2 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 EIE81293.1 - 3.8e-16 58.6 0.0 1.5e-15 56.6 0.0 2.1 2 0 0 2 2 2 1 Transcription- and export-related complex subunit Glyco_hydro_16 PF00722.16 EIE81294.1 - 3.6e-21 75.2 1.9 1.1e-20 73.7 1.3 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 lci PF12197.3 EIE81294.1 - 0.0096 15.4 1.4 1 9.0 0.1 3.0 3 0 0 3 3 3 2 Bacillus cereus group antimicrobial protein Cyclin PF08613.6 EIE81295.1 - 1.6e-08 35.1 0.3 1.6e-08 35.1 0.2 1.8 2 0 0 2 2 2 1 Cyclin DUF4037 PF13228.1 EIE81295.1 - 0.014 15.6 0.6 0.026 14.7 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4037) Dna2 PF08696.6 EIE81297.1 - 3e-56 190.0 0.2 5.1e-56 189.2 0.1 1.3 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_11 PF13086.1 EIE81297.1 - 2.6e-14 53.4 0.0 5.7e-14 52.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.1 EIE81297.1 - 8.3e-11 41.6 0.0 1.8e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EIE81297.1 - 1.9e-09 37.1 0.1 6.8e-09 35.3 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain PDDEXK_1 PF12705.2 EIE81297.1 - 1.7e-08 34.1 0.0 4.3e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily AAA_30 PF13604.1 EIE81297.1 - 1.9e-08 34.1 0.0 7.5e-08 32.1 0.0 2.0 1 1 1 2 2 2 1 AAA domain Cas_Cas4 PF01930.12 EIE81297.1 - 6.5e-05 22.9 0.0 0.00024 21.0 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function DUF83 UvrD-helicase PF00580.16 EIE81297.1 - 0.00092 18.5 0.0 0.002 17.4 0.0 1.6 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain SRP54 PF00448.17 EIE81297.1 - 0.003 17.0 0.2 0.0063 15.9 0.2 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain PIF1 PF05970.9 EIE81297.1 - 0.0072 15.3 0.0 0.26 10.1 0.0 2.3 1 1 1 2 2 2 1 PIF1-like helicase AAA_25 PF13481.1 EIE81297.1 - 0.0076 15.6 0.0 0.02 14.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF87 PF01935.12 EIE81297.1 - 0.017 14.9 0.5 0.065 13.0 0.4 2.0 1 0 0 1 1 1 0 Domain of unknown function DUF87 MobB PF03205.9 EIE81297.1 - 0.021 14.5 0.0 0.052 13.2 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ResIII PF04851.10 EIE81297.1 - 0.021 14.6 0.1 0.048 13.5 0.1 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_16 PF13191.1 EIE81297.1 - 0.024 14.5 0.5 0.24 11.3 0.0 2.9 4 0 0 4 4 4 0 AAA ATPase domain Helicase_RecD PF05127.9 EIE81297.1 - 0.036 13.7 0.1 0.097 12.3 0.0 1.8 2 0 0 2 2 2 0 Helicase AAA PF00004.24 EIE81297.1 - 0.054 13.7 0.0 0.17 12.1 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.18 EIE81297.1 - 0.08 12.3 0.0 0.2 11.0 0.0 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_10 PF12846.2 EIE81297.1 - 0.081 12.3 0.1 0.66 9.3 0.0 2.4 2 1 0 2 2 2 0 AAA-like domain AAA_17 PF13207.1 EIE81297.1 - 0.12 13.2 0.1 0.84 10.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.15 EIE81298.1 - 1.9e-101 339.6 0.9 2.1e-101 339.4 0.6 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EIE81298.1 - 2.6e-10 39.8 0.2 6.8e-10 38.4 0.1 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family zf-CHC2 PF01807.15 EIE81298.1 - 0.0022 17.4 0.1 0.034 13.7 0.0 2.2 2 0 0 2 2 2 1 CHC2 zinc finger VPS9 PF02204.13 EIE81299.1 - 3.1e-16 59.2 0.0 8.9e-16 57.8 0.0 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_2 PF12796.2 EIE81299.1 - 3.6e-15 56.0 0.0 8.5e-07 29.2 0.0 3.6 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EIE81299.1 - 1.3e-11 43.5 0.8 0.18 12.1 0.0 6.2 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.1 EIE81299.1 - 2.5e-10 40.2 4.0 0.46 10.8 0.0 5.2 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 EIE81299.1 - 2.8e-10 40.4 2.5 0.00049 20.5 0.0 4.3 4 1 0 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.25 EIE81299.1 - 3.1e-09 36.1 2.0 0.0081 15.9 0.0 4.8 5 0 0 5 5 5 3 Ankyrin repeat PX PF00787.19 EIE81299.1 - 0.0001 22.0 0.4 0.00027 20.7 0.1 1.9 2 0 0 2 2 2 1 PX domain DUF4315 PF14193.1 EIE81299.1 - 0.057 13.3 0.2 0.13 12.1 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4315) Pkinase PF00069.20 EIE81300.1 - 3e-19 69.1 0.0 4.7e-19 68.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE81300.1 - 4.4e-09 35.7 0.0 7.7e-09 35.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase zf-Tim10_DDP PF02953.10 EIE81301.1 - 5.1e-24 83.3 0.3 6.5e-24 83.0 0.2 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF3398 PF11878.3 EIE81301.1 - 0.028 14.2 0.1 0.038 13.8 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3398) DUF89 PF01937.14 EIE81302.1 - 0.11 11.2 0.5 7.7 5.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF89 DUF2009 PF09418.5 EIE81303.1 - 4.2e-190 632.4 1.0 5.4e-190 632.0 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) zf-B_box PF00643.19 EIE81303.1 - 1.9e-05 24.4 8.9 4.6e-05 23.2 6.1 1.6 1 0 0 1 1 1 1 B-box zinc finger IBR PF01485.16 EIE81303.1 - 0.29 11.0 9.5 1.3 8.9 6.6 2.0 1 1 0 1 1 1 0 IBR domain NOB1_Zn_bind PF08772.6 EIE81303.1 - 1.2 9.0 5.7 4.8 7.0 4.0 2.0 1 1 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like Cript PF10235.4 EIE81303.1 - 6 7.3 8.0 1.7 9.0 3.0 2.0 2 0 0 2 2 2 0 Microtubule-associated protein CRIPT p450 PF00067.17 EIE81304.1 - 4e-74 249.8 0.4 5e-74 249.5 0.3 1.0 1 0 0 1 1 1 1 Cytochrome P450 Chorismate_bind PF00425.13 EIE81305.1 - 2.2e-85 286.1 0.0 3.6e-85 285.3 0.0 1.4 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.23 EIE81305.1 - 1.2e-27 96.5 0.3 6.3e-17 61.6 0.0 2.3 1 1 1 2 2 2 2 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 EIE81305.1 - 1.9e-20 73.2 0.1 6e-20 71.6 0.1 1.9 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 EIE81305.1 - 2.2e-05 24.0 0.1 5.3e-05 22.7 0.0 1.6 1 1 0 1 1 1 1 Peptidase C26 CTD_bind PF04818.8 EIE81306.1 - 0.0062 16.7 0.0 0.012 15.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II-binding domain. Glyco_hydro_28 PF00295.12 EIE81307.1 - 8.3e-68 228.7 15.0 1.1e-67 228.3 10.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 CarbpepA_inh PF02977.10 EIE81307.1 - 6.8 6.3 7.5 1.7 8.3 0.3 2.7 2 0 0 2 2 2 0 Carboxypeptidase A inhibitor Acetyltransf_3 PF13302.1 EIE81308.1 - 6e-23 81.5 0.0 9.6e-23 80.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EIE81308.1 - 0.00011 22.1 0.0 0.00024 21.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EIE81308.1 - 0.00014 21.8 0.0 0.00025 21.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 EIE81308.1 - 0.00025 20.9 0.0 0.00053 19.8 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FAR1 PF03101.10 EIE81309.1 - 1.3e-05 25.6 0.3 3.3e-05 24.3 0.2 1.7 1 0 0 1 1 1 1 FAR1 DNA-binding domain HSF_DNA-bind PF00447.12 EIE81310.1 - 0.02 15.0 0.1 0.02 15.0 0.1 2.0 3 0 0 3 3 3 0 HSF-type DNA-binding CAP_GLY PF01302.20 EIE81311.1 - 1.4e-15 56.7 0.1 1.8e-15 56.3 0.1 1.2 1 0 0 1 1 1 1 CAP-Gly domain Cse1 PF08506.5 EIE81312.1 - 2.1e-127 424.7 5.7 4.1e-127 423.7 4.0 1.5 1 0 0 1 1 1 1 Cse1 CAS_CSE1 PF03378.10 EIE81312.1 - 6.8e-80 268.4 3.3 1.1e-35 122.7 1.0 3.6 2 1 2 4 4 4 3 CAS/CSE protein, C-terminus Arm PF00514.18 EIE81312.1 - 0.1 12.4 0.0 14 5.7 0.0 3.4 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat DAO PF01266.19 EIE81314.1 - 7.6e-46 156.6 0.0 2.6e-44 151.5 0.0 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIE81314.1 - 1.7e-07 31.1 0.0 3.9e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EIE81314.1 - 1.3e-06 28.4 0.0 0.00036 20.4 0.0 3.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EIE81314.1 - 0.0002 20.3 0.0 0.0025 16.7 0.0 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_9 PF13454.1 EIE81314.1 - 0.0034 17.1 0.0 0.32 10.7 0.0 2.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 EIE81314.1 - 0.0036 17.6 0.0 0.044 14.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EIE81314.1 - 0.0069 15.4 0.0 0.015 14.3 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Het-C PF07217.6 EIE81314.1 - 0.068 11.3 0.0 0.11 10.7 0.0 1.2 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C Pyr_redox_3 PF13738.1 EIE81314.1 - 0.12 12.4 0.0 4.5 7.2 0.0 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_hydro_28 PF00295.12 EIE81315.1 - 1.3e-55 188.6 22.0 2.4e-55 187.7 15.2 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Rota_NS35 PF02509.9 EIE81315.1 - 0.0074 15.0 0.0 0.013 14.2 0.0 1.3 1 0 0 1 1 1 1 Rotavirus non-structural protein 35 Glyco_hydro_28 PF00295.12 EIE81316.1 - 2.2e-67 227.3 17.2 2.8e-67 226.9 11.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 PNP_UDP_1 PF01048.15 EIE81317.1 - 1.8e-26 92.5 0.8 2.8e-20 72.2 0.1 2.0 1 1 1 2 2 2 2 Phosphorylase superfamily PPP5 PF08321.7 EIE81317.1 - 0.036 14.0 0.0 0.063 13.3 0.0 1.3 1 0 0 1 1 1 0 PPP5 TPR repeat region zf-CCHC PF00098.18 EIE81319.1 - 7.4e-10 38.2 8.5 0.00032 20.4 2.9 2.6 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.1 EIE81319.1 - 0.024 14.1 4.0 0.03 13.7 0.8 2.4 1 1 1 2 2 2 0 Zinc knuckle TNFR_c6 PF00020.13 EIE81319.1 - 0.026 14.5 2.6 0.026 14.5 1.8 2.0 3 0 0 3 3 3 0 TNFR/NGFR cysteine-rich region RseA_C PF03873.8 EIE81319.1 - 0.074 12.9 0.1 0.18 11.7 0.1 1.6 1 0 0 1 1 1 0 Anti sigma-E protein RseA, C-terminal domain zf-CCHC_4 PF14392.1 EIE81319.1 - 0.086 12.5 9.7 0.15 11.7 0.3 2.5 2 0 0 2 2 2 0 Zinc knuckle zinc-ribbons_6 PF07191.7 EIE81319.1 - 1.2 9.0 6.7 2.4 7.9 4.7 1.5 1 0 0 1 1 1 0 zinc-ribbons zf-C2H2_4 PF13894.1 EIE81321.1 - 8.3e-06 25.7 3.7 0.014 15.7 0.2 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EIE81321.1 - 0.17 11.9 4.9 4.9 7.3 0.3 3.4 4 0 0 4 4 4 0 C2H2 type zinc-finger (2 copies) DDE_3 PF13358.1 EIE81322.1 - 1.1e-28 99.8 0.0 2e-28 98.9 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 EIE81322.1 - 8.9e-10 38.7 0.2 2.6e-09 37.2 0.0 1.8 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.1 EIE81322.1 - 7e-08 33.1 0.3 1.8e-07 31.8 0.0 1.9 2 0 0 2 2 1 1 Homeodomain-like domain HTH_28 PF13518.1 EIE81322.1 - 2e-07 30.8 5.7 1.7e-06 27.8 0.6 3.1 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_23 PF13384.1 EIE81322.1 - 2.2e-07 30.2 0.4 8.5e-05 22.0 0.1 2.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_17 PF12728.2 EIE81322.1 - 0.00054 20.1 0.2 0.57 10.4 0.1 2.6 2 0 0 2 2 2 2 Helix-turn-helix domain Terminase_5 PF06056.7 EIE81322.1 - 0.0024 17.4 0.1 0.018 14.5 0.0 2.4 2 1 0 2 2 2 1 Putative ATPase subunit of terminase (gpP-like) HTH_Tnp_1 PF01527.15 EIE81322.1 - 0.0051 16.7 1.6 0.0072 16.2 0.2 1.9 2 0 0 2 2 2 1 Transposase rve PF00665.21 EIE81322.1 - 0.0065 16.5 0.0 0.065 13.3 0.0 2.4 2 1 1 3 3 3 1 Integrase core domain LZ_Tnp_IS481 PF13011.1 EIE81322.1 - 0.027 14.8 0.4 0.093 13.0 0.2 1.9 2 0 0 2 2 1 0 leucine-zipper of insertion element IS481 DUF746 PF05344.6 EIE81322.1 - 0.036 13.5 0.0 0.077 12.5 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF746) HTH_Tnp_ISL3 PF13542.1 EIE81322.1 - 0.045 12.9 0.4 0.11 11.7 0.3 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_30 PF13556.1 EIE81322.1 - 0.21 11.1 1.0 0.48 10.0 0.2 1.9 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain DUF2428 PF10350.4 EIE81323.1 - 0.059 12.3 0.1 0.076 12.0 0.1 1.1 1 0 0 1 1 1 0 Putative death-receptor fusion protein (DUF2428) FoP_duplication PF13865.1 EIE81324.1 - 4.9e-11 42.9 10.1 4.9e-11 42.9 7.0 1.7 1 1 1 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 FRG1 PF06229.7 EIE81324.1 - 0.22 10.9 7.7 0.26 10.7 5.3 1.1 1 0 0 1 1 1 0 FRG1-like family Dynactin_p62 PF05502.8 EIE81324.1 - 0.32 9.7 8.5 0.34 9.6 5.9 1.0 1 0 0 1 1 1 0 Dynactin p62 family Bud13 PF09736.4 EIE81324.1 - 0.51 10.5 12.4 0.66 10.2 8.6 1.4 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex DUF3926 PF13080.1 EIE81324.1 - 0.55 9.8 0.1 0.55 9.8 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3926) VSG_B PF13206.1 EIE81324.1 - 1.6 7.7 14.5 1.9 7.5 10.0 1.0 1 0 0 1 1 1 0 Trypanosomal VSG domain Peptidase_M24 PF00557.19 EIE81325.1 - 3.6e-19 69.1 0.0 5.5e-19 68.5 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 EIE81325.1 - 0.0096 16.4 0.0 0.056 13.9 0.0 2.1 2 1 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Alginate_lyase PF05426.7 EIE81326.1 - 1.7e-09 37.4 0.1 4.9e-09 35.9 0.1 1.7 1 1 0 1 1 1 1 Alginate lyase Vfa1 PF08432.5 EIE81327.1 - 3.1e-25 89.2 13.9 3.6e-25 89.0 9.7 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 DDHD PF02862.12 EIE81327.1 - 0.021 14.6 7.9 0.028 14.2 5.5 1.3 1 0 0 1 1 1 0 DDHD domain Tim54 PF11711.3 EIE81327.1 - 0.022 13.3 10.1 0.028 13.0 7.0 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 O-FucT PF10250.4 EIE81327.1 - 0.034 13.2 4.7 0.054 12.6 3.3 1.3 1 0 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase SprA-related PF12118.3 EIE81327.1 - 0.043 13.1 8.7 0.047 13.0 6.0 1.1 1 0 0 1 1 1 0 SprA-related family Merozoite_SPAM PF07133.6 EIE81327.1 - 0.08 12.8 19.4 0.11 12.4 13.4 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Prog_receptor PF02161.10 EIE81327.1 - 0.2 10.4 3.6 0.22 10.3 2.5 1.1 1 0 0 1 1 1 0 Progesterone receptor Spore_coat_CotO PF14153.1 EIE81327.1 - 0.23 10.8 21.7 0.3 10.5 15.0 1.1 1 0 0 1 1 1 0 Spore coat protein CotO FAM176 PF14851.1 EIE81327.1 - 0.42 10.2 8.4 0.61 9.7 5.8 1.3 1 0 0 1 1 1 0 FAM176 family Ycf1 PF05758.7 EIE81327.1 - 0.58 7.8 13.2 0.66 7.6 9.1 1.1 1 0 0 1 1 1 0 Ycf1 DHHW PF14286.1 EIE81327.1 - 0.6 9.3 5.9 0.74 9.0 4.1 1.1 1 0 0 1 1 1 0 DHHW protein TraH_2 PF06871.6 EIE81327.1 - 0.83 9.0 4.0 1.1 8.6 2.8 1.1 1 0 0 1 1 1 0 TraH_2 Cytomega_UL84 PF06284.6 EIE81327.1 - 0.88 7.9 7.6 1.2 7.4 5.2 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein GOLD_2 PF13897.1 EIE81327.1 - 0.98 9.6 4.5 1.4 9.1 3.1 1.3 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking SID-1_RNA_chan PF13965.1 EIE81327.1 - 1.3 7.1 4.9 1.7 6.7 3.4 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 YqfQ PF14181.1 EIE81327.1 - 1.3 9.0 18.4 0.073 13.1 8.9 1.7 2 0 0 2 2 2 0 YqfQ-like protein RNA_pol_Rpc4 PF05132.9 EIE81327.1 - 2.9 7.9 12.4 1.1 9.2 6.3 2.0 2 0 0 2 2 2 0 RNA polymerase III RPC4 CDC45 PF02724.9 EIE81327.1 - 3.3 5.6 14.0 3.8 5.4 9.7 1.0 1 0 0 1 1 1 0 CDC45-like protein Peptidase_C58 PF03543.9 EIE81330.1 - 0.012 15.1 0.1 1.7 8.0 0.0 2.3 2 0 0 2 2 2 0 Yersinia/Haemophilus virulence surface antigen Npa1 PF11707.3 EIE81331.1 - 3.2e-69 233.4 1.9 3.2e-69 233.4 1.3 2.8 3 0 0 3 3 3 1 Ribosome 60S biogenesis N-terminal Creb_binding PF09030.5 EIE81331.1 - 0.051 13.7 0.0 0.18 12.0 0.0 1.9 1 0 0 1 1 1 0 Creb binding RRM_1 PF00076.17 EIE81332.1 - 3.2e-23 81.1 0.0 6.1e-11 41.7 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE81332.1 - 2.4e-16 59.4 0.0 1.2e-07 31.5 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE81332.1 - 7.2e-14 51.3 0.1 3.8e-06 26.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PUF PF00806.14 EIE81332.1 - 1.3e-12 46.4 3.3 0.012 15.0 0.0 6.4 6 0 0 6 6 6 3 Pumilio-family RNA binding repeat RRM_3 PF08777.6 EIE81332.1 - 0.043 13.6 0.0 1.9 8.4 0.0 2.5 2 0 0 2 2 2 0 RNA binding motif Pinin_SDK_memA PF04696.8 EIE81333.1 - 7.6e-25 87.0 18.1 7.6e-25 87.0 12.5 1.7 2 0 0 2 2 2 1 pinin/SDK/memA/ protein conserved region DUF262 PF03235.9 EIE81333.1 - 0.55 10.1 9.6 0.73 9.7 6.6 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF262 hDGE_amylase PF14701.1 EIE81333.1 - 2.8 6.7 11.2 2.6 6.8 6.9 1.4 1 1 1 2 2 2 0 glucanotransferase domain of human glycogen debranching enzyme UPF0242 PF06785.6 EIE81333.1 - 8.7 4.9 14.6 6.6 5.2 9.3 1.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) Ank_2 PF12796.2 EIE81334.1 - 7.9e-18 64.5 1.3 2.6e-12 46.8 0.1 2.9 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EIE81334.1 - 3.1e-13 49.8 0.5 1.1e-10 41.6 0.0 3.6 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.25 EIE81334.1 - 2.4e-12 45.9 5.6 3.8e-07 29.5 0.0 4.7 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.1 EIE81334.1 - 1.1e-09 37.5 2.3 8.3e-05 22.4 0.0 5.1 5 0 0 5 5 5 1 Ankyrin repeat Ank_5 PF13857.1 EIE81334.1 - 1.5e-09 37.7 0.2 3.4e-06 27.1 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Filament PF00038.16 EIE81334.1 - 0.0068 15.9 16.2 0.09 12.2 4.1 2.2 2 0 0 2 2 2 2 Intermediate filament protein KilA-N PF04383.8 EIE81334.1 - 0.0084 15.7 0.1 0.094 12.3 0.1 2.5 1 1 0 1 1 1 1 KilA-N domain Asp-B-Hydro_N PF05279.6 EIE81334.1 - 0.076 12.8 8.8 0.12 12.1 6.1 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF484 PF04340.7 EIE81334.1 - 1.8 8.0 8.0 1.9 7.9 0.6 2.3 1 1 1 2 2 2 0 Protein of unknown function, DUF484 FlaC_arch PF05377.6 EIE81334.1 - 2.5 8.0 7.9 17 5.4 2.3 3.0 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.7 EIE81334.1 - 6.2 6.6 9.0 0.38 10.5 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) V_ATPase_I PF01496.14 EIE81334.1 - 6.5 4.4 9.9 3.4 5.4 5.6 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF342 PF03961.8 EIE81334.1 - 9.8 4.4 10.3 17 3.6 7.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Hydrolase_6 PF13344.1 EIE81335.1 - 9.1e-30 102.5 0.0 3.9e-29 100.5 0.0 2.1 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase EF-hand_7 PF13499.1 EIE81335.1 - 5.2e-17 61.7 0.4 8.2e-11 41.8 0.0 2.7 3 0 0 3 3 2 2 EF-hand domain pair Hydrolase_like PF13242.1 EIE81335.1 - 9.2e-15 54.1 0.0 2e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EIE81335.1 - 1.4e-12 48.4 0.0 3.5e-12 47.2 0.0 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase EF-hand_1 PF00036.27 EIE81335.1 - 2.7e-12 45.0 0.3 4.3e-05 22.5 0.0 4.1 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 EIE81335.1 - 3.7e-11 41.9 0.7 2.7e-05 23.6 0.0 3.6 3 1 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 EIE81335.1 - 2.5e-10 39.7 0.2 4.2e-08 32.6 0.1 3.3 2 1 1 3 3 3 2 EF-hand domain pair HAD_2 PF13419.1 EIE81335.1 - 4.4e-08 33.5 0.1 0.0024 18.1 0.0 3.2 3 1 0 3 3 2 2 Haloacid dehalogenase-like hydrolase EF-hand_5 PF13202.1 EIE81335.1 - 0.00095 18.4 1.1 0.0088 15.3 0.0 3.1 4 0 0 4 4 4 1 EF hand EF-hand_9 PF14658.1 EIE81335.1 - 0.0077 16.1 0.0 1.6 8.6 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain Hydrolase_3 PF08282.7 EIE81335.1 - 0.011 15.2 0.0 2.4 7.6 0.0 2.4 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Ribosomal_L7Ae PF01248.21 EIE81335.1 - 0.11 12.0 0.0 0.85 9.1 0.0 2.3 2 0 0 2 2 2 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNA_pol_Rpb4 PF03874.11 EIE81335.1 - 0.19 11.7 1.0 8.6 6.3 0.1 3.3 4 0 0 4 4 4 0 RNA polymerase Rpb4 HSP70 PF00012.15 EIE81336.1 - 0.00078 17.4 0.0 0.002 16.1 0.0 1.5 1 1 0 1 1 1 1 Hsp70 protein HSP70 PF00012.15 EIE81337.1 - 2.9e-07 28.8 0.0 0.00051 18.0 0.0 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 EIE81337.1 - 0.00011 20.8 0.0 0.02 13.5 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein BcrAD_BadFG PF01869.15 EIE81337.1 - 0.06 12.6 0.0 0.09 12.0 0.0 1.2 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family EMP24_GP25L PF01105.19 EIE81338.1 - 8.1e-22 77.8 0.6 1e-21 77.4 0.4 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Y_Y_Y PF07495.8 EIE81338.1 - 0.038 13.7 0.1 16 5.3 0.0 2.8 2 1 1 3 3 3 0 Y_Y_Y domain Sugar_tr PF00083.19 EIE81339.1 - 6.8e-118 394.0 18.8 7.7e-118 393.9 13.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIE81339.1 - 9.8e-24 83.7 22.1 1.5e-23 83.1 11.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EIE81339.1 - 6.1e-05 21.4 2.2 6.1e-05 21.4 1.5 2.0 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Lig_chan PF00060.21 EIE81339.1 - 7.2 6.3 5.8 1.1 8.9 0.8 2.1 2 0 0 2 2 2 0 Ligand-gated ion channel ADH_N PF08240.7 EIE81340.1 - 3.4e-24 84.6 4.6 5.4e-24 84.0 3.2 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIE81340.1 - 5e-18 64.8 0.0 7.2e-18 64.3 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EIE81340.1 - 0.0011 18.1 0.0 0.0019 17.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lipase_3 PF01764.20 EIE81342.1 - 1.6e-38 131.5 0.1 2.2e-38 131.0 0.1 1.2 1 0 0 1 1 1 1 Lipase (class 3) Esterase PF00756.15 EIE81342.1 - 0.012 15.0 0.0 0.019 14.4 0.0 1.2 1 0 0 1 1 1 0 Putative esterase DUF2974 PF11187.3 EIE81342.1 - 0.015 14.6 0.2 0.052 12.9 0.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) PGAP1 PF07819.8 EIE81342.1 - 0.017 14.7 0.5 0.046 13.2 0.1 2.0 2 1 0 2 2 2 0 PGAP1-like protein Cutinase PF01083.17 EIE81342.1 - 0.02 14.6 0.0 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 Cutinase Abhydrolase_6 PF12697.2 EIE81342.1 - 0.068 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF605 PF04652.11 EIE81342.1 - 0.87 8.9 6.9 1.2 8.4 4.8 1.1 1 0 0 1 1 1 0 Vta1 like HMG_box PF00505.14 EIE81343.1 - 5.8e-32 109.7 21.3 2.3e-18 66.2 2.0 3.7 4 0 0 4 4 4 2 HMG (high mobility group) box HMG_box_2 PF09011.5 EIE81343.1 - 9.4e-30 102.7 12.9 5e-16 58.8 0.5 2.8 2 1 1 3 3 3 2 HMG-box domain HMG_box_5 PF14887.1 EIE81343.1 - 0.00017 21.3 4.1 0.00061 19.5 0.3 2.4 2 0 0 2 2 2 1 HMG (high mobility group) box 5 CHDNT PF08073.7 EIE81343.1 - 0.0059 16.2 0.2 0.013 15.1 0.1 1.6 1 0 0 1 1 1 1 CHDNT (NUC034) domain Peptidase_M61 PF05299.7 EIE81343.1 - 0.18 11.7 1.7 0.34 10.8 0.0 2.2 2 1 0 2 2 2 0 M61 glycyl aminopeptidase DUF1014 PF06244.7 EIE81343.1 - 0.19 11.9 13.1 1.5 9.0 3.0 3.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1014) DUF1289 PF06945.8 EIE81343.1 - 3.5 7.1 6.6 22 4.6 1.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1289) Septin PF00735.13 EIE81344.1 - 1e-97 326.5 2.0 1e-96 323.3 1.4 2.0 1 1 0 1 1 1 1 Septin GTP_EFTU PF00009.22 EIE81344.1 - 0.0058 16.0 0.1 0.12 11.7 0.0 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EIE81344.1 - 0.14 11.9 1.0 0.48 10.2 0.0 2.1 2 0 0 2 2 2 0 Dynamin family cNMP_binding PF00027.24 EIE81345.1 - 2.3e-44 149.1 0.1 2.9e-21 75.0 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Methyltransf_16 PF10294.4 EIE81345.1 - 6.8e-30 103.7 0.3 2.6e-29 101.8 0.0 2.1 2 1 1 3 3 3 1 Putative methyltransferase RIIa PF02197.12 EIE81345.1 - 4.8e-08 32.3 0.3 1.8e-07 30.4 0.2 2.1 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Methyltransf_18 PF12847.2 EIE81345.1 - 2.6e-06 27.9 0.0 7.6e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIE81345.1 - 0.00035 20.9 0.1 0.0046 17.3 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIE81345.1 - 0.002 17.7 0.0 0.0046 16.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EIE81345.1 - 0.0022 17.3 0.0 0.0049 16.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EIE81345.1 - 0.0095 16.2 0.0 0.044 14.1 0.0 2.2 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIE81345.1 - 0.025 14.2 0.0 0.052 13.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 EIE81345.1 - 0.082 12.9 0.0 0.31 11.0 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain FRD2 PF03197.8 EIE81345.1 - 0.11 12.9 4.8 1.1 9.8 0.8 2.5 2 0 0 2 2 2 0 Bacteriophage FRD2 protein RRN9 PF10680.4 EIE81346.1 - 0.076 12.7 0.1 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor WD40 PF00400.27 EIE81346.1 - 0.15 11.9 2.1 0.21 11.5 0.1 2.3 3 0 0 3 3 3 0 WD domain, G-beta repeat Peptidase_M48 PF01435.13 EIE81350.1 - 2.9e-54 184.0 0.0 3.9e-54 183.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.6 EIE81350.1 - 7.4e-06 25.1 0.9 4.4e-05 22.6 1.0 2.0 2 0 0 2 2 2 1 BlaR1 peptidase M56 SprT-like PF10263.4 EIE81350.1 - 0.071 12.7 0.1 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 SprT-like family 2TM PF13239.1 EIE81350.1 - 0.67 10.0 9.1 0.25 11.4 1.4 2.8 2 0 0 2 2 2 0 2TM domain zf-H2C2_2 PF13465.1 EIE81351.1 - 3e-20 71.4 28.2 8.3e-08 32.1 0.5 5.4 6 0 0 6 6 6 3 Zinc-finger double domain zf-C2H2 PF00096.21 EIE81351.1 - 1.1e-18 66.3 23.1 0.00013 22.1 0.8 4.9 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIE81351.1 - 1.8e-12 46.6 19.2 0.016 15.4 1.8 4.6 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EIE81351.1 - 6.2e-05 23.0 7.6 2.3 8.4 1.5 4.9 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding OAF PF14941.1 EIE81351.1 - 0.074 12.1 1.0 0.11 11.5 0.7 1.2 1 0 0 1 1 1 0 Transcriptional regulator, Out at first Ogr_Delta PF04606.7 EIE81351.1 - 0.29 10.8 4.7 4.2 7.0 0.2 3.2 1 1 2 3 3 3 0 Ogr/Delta-like zinc finger zf-met PF12874.2 EIE81351.1 - 0.65 10.2 13.7 2.7 8.3 0.5 5.2 5 0 0 5 5 5 0 Zinc-finger of C2H2 type zf-TRAF PF02176.13 EIE81351.1 - 2.6 8.5 9.0 12 6.3 0.3 2.6 1 1 2 3 3 3 0 TRAF-type zinc finger zf-H2C2_5 PF13909.1 EIE81351.1 - 2.9 8.2 16.2 0.52 10.6 1.8 4.6 5 0 0 5 5 5 0 C2H2-type zinc-finger domain Lipase_3 PF01764.20 EIE81352.1 - 5e-37 126.6 0.1 6.9e-37 126.1 0.1 1.2 1 0 0 1 1 1 1 Lipase (class 3) Esterase PF00756.15 EIE81352.1 - 0.0028 17.1 0.0 0.0043 16.4 0.0 1.2 1 0 0 1 1 1 1 Putative esterase DUF2974 PF11187.3 EIE81352.1 - 0.02 14.2 0.4 0.074 12.3 0.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.2 EIE81352.1 - 0.056 13.3 0.0 0.14 12.0 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family PGAP1 PF07819.8 EIE81352.1 - 0.084 12.4 0.1 0.19 11.3 0.1 1.5 1 1 0 1 1 1 0 PGAP1-like protein Glyco_hydro_114 PF03537.8 EIE81352.1 - 0.15 11.8 0.2 24 4.7 0.0 3.0 2 1 0 2 2 2 0 Glycoside-hydrolase family GH114 RRM_1 PF00076.17 EIE81353.1 - 8.3e-34 115.0 0.0 2.4e-16 59.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE81353.1 - 1.7e-28 98.3 0.0 1.3e-15 57.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE81353.1 - 1.4e-15 56.8 0.0 6.5e-10 38.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EIE81353.1 - 1.5e-06 27.8 0.0 0.012 15.4 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif MIP-T3 PF10243.4 EIE81353.1 - 0.0013 17.3 63.4 0.0017 16.9 43.9 1.2 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Shadoo PF14999.1 EIE81353.1 - 1.7 8.4 23.3 21 4.9 15.2 3.0 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective DUF904 PF06005.7 EIE81355.1 - 0.061 13.6 0.1 0.061 13.6 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF904) WEMBL PF05701.6 EIE81355.1 - 0.072 11.5 9.2 0.1 11.0 6.4 1.2 1 0 0 1 1 1 0 Weak chloroplast movement under blue light TPD52 PF04201.10 EIE81355.1 - 0.093 12.4 4.9 0.15 11.7 3.4 1.5 1 1 0 1 1 1 0 Tumour protein D52 family DUF948 PF06103.6 EIE81355.1 - 0.12 12.2 1.7 6.6 6.6 0.1 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF4349 PF14257.1 EIE81355.1 - 0.14 11.3 3.1 0.08 12.1 0.7 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) Latarcin PF10279.4 EIE81355.1 - 0.17 12.0 6.1 4.1 7.6 0.1 2.3 1 1 1 2 2 2 0 Latarcin precursor DUF4164 PF13747.1 EIE81355.1 - 0.53 10.4 5.6 1 9.5 1.6 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) DUF1664 PF07889.7 EIE81355.1 - 1.3 8.7 7.0 2.6 7.8 1.0 3.0 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) Syntaxin-6_N PF09177.6 EIE81355.1 - 1.4 9.3 6.4 3.5 8.0 1.0 2.6 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF2203 PF09969.4 EIE81355.1 - 1.9 8.7 6.0 63 3.8 4.1 2.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Ribonuc_L-PSP PF01042.16 EIE81356.1 - 1.6e-46 156.9 0.2 1.8e-46 156.8 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP WD40 PF00400.27 EIE81357.1 - 2.7e-54 179.1 22.2 4.3e-09 35.8 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EIE81357.1 - 4.8e-05 23.1 0.0 0.064 12.9 0.0 2.6 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Memo PF01875.12 EIE81358.1 - 5.8e-46 156.5 0.4 3.1e-23 82.0 0.0 3.2 1 1 1 2 2 2 2 Memo-like protein Peptidase_S8 PF00082.17 EIE81358.1 - 9.5e-25 87.2 0.7 1.5e-24 86.6 0.5 1.3 1 0 0 1 1 1 1 Subtilase family Ecl1 PF12855.2 EIE81359.1 - 1.2e-09 37.2 7.7 3.1e-09 35.9 5.5 1.6 2 0 0 2 2 2 1 Life-span regulatory factor DUF2116 PF09889.4 EIE81359.1 - 0.019 14.7 0.8 0.025 14.3 0.5 1.2 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Calcipressin PF04847.7 EIE81359.1 - 0.038 13.5 0.1 0.047 13.2 0.0 1.1 1 0 0 1 1 1 0 Calcipressin Omega-toxin PF06357.6 EIE81359.1 - 0.097 12.2 3.9 0.24 10.9 1.1 2.1 2 0 0 2 2 2 0 Omega-atracotoxin PLATZ PF04640.9 EIE81359.1 - 0.25 11.5 4.9 0.44 10.7 3.4 1.3 1 0 0 1 1 1 0 PLATZ transcription factor DUF3079 PF11278.3 EIE81359.1 - 0.48 10.0 4.4 0.79 9.3 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3079) NAC PF01849.13 EIE81360.1 - 1e-20 73.0 0.1 2.5e-20 71.7 0.0 1.7 2 0 0 2 2 2 1 NAC domain DDE_1 PF03184.14 EIE81367.1 - 0.0098 15.0 0.0 0.031 13.4 0.0 1.8 1 0 0 1 1 1 1 DDE superfamily endonuclease RRM_6 PF14259.1 EIE81370.1 - 6.9e-08 32.3 0.0 8.3e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EIE81370.1 - 7.7e-08 31.8 0.0 9.1e-08 31.6 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE81370.1 - 0.00027 20.7 0.0 0.00039 20.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 EIE81371.1 - 1.1e-35 120.1 7.5 1.4e-08 34.2 0.0 7.2 7 1 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 EIE81371.1 - 5.1e-07 28.2 1.9 0.14 10.2 0.1 4.6 2 2 1 4 4 4 3 Nucleoporin Nup120/160 eIF2A PF08662.6 EIE81371.1 - 0.0024 17.5 0.6 0.047 13.3 0.0 2.7 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 EIE81371.1 - 0.018 13.8 0.0 0.28 9.8 0.0 2.5 1 1 1 2 2 2 0 Nup133 N terminal like Hira PF07569.6 EIE81371.1 - 0.12 11.6 0.3 20 4.2 0.0 3.3 3 1 1 4 4 4 0 TUP1-like enhancer of split Mito_carr PF00153.22 EIE81372.1 - 1.3e-69 229.9 1.0 9e-24 83.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein 60KD_IMP PF02096.15 EIE81372.1 - 0.0098 15.5 0.3 0.018 14.6 0.0 1.9 2 0 0 2 2 2 1 60Kd inner membrane protein LAGLIDADG_2 PF03161.8 EIE81372.1 - 0.042 13.7 0.1 0.12 12.2 0.0 1.6 1 1 0 2 2 2 0 LAGLIDADG DNA endonuclease family Reo_P9 PF06043.6 EIE81372.1 - 0.054 12.5 0.1 0.12 11.3 0.0 1.6 2 0 0 2 2 2 0 Reovirus P9-like family Pkinase PF00069.20 EIE81373.1 - 3.8e-66 222.9 0.0 6.3e-66 222.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE81373.1 - 4.6e-36 124.2 0.0 8.4e-36 123.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.17 EIE81373.1 - 5.1e-17 61.3 26.9 1.4e-09 37.4 8.1 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) HR1 PF02185.11 EIE81373.1 - 9.9e-11 41.2 8.2 1.7e-05 24.4 0.2 2.5 2 0 0 2 2 2 2 Hr1 repeat Pkinase_C PF00433.19 EIE81373.1 - 2.7e-10 40.6 2.2 3.9e-10 40.1 0.4 2.2 2 0 0 2 2 2 1 Protein kinase C terminal domain PAT1 PF09770.4 EIE81373.1 - 0.046 11.9 53.8 0.0071 14.6 34.0 1.8 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 C1_2 PF03107.11 EIE81373.1 - 0.39 10.8 21.0 0.98 9.5 7.3 2.8 2 0 0 2 2 2 0 C1 domain FYVE_2 PF02318.11 EIE81373.1 - 5.1 7.0 21.6 1.9 8.3 6.4 2.7 1 1 0 2 2 2 0 FYVE-type zinc finger C1_3 PF07649.7 EIE81373.1 - 8.1 6.5 18.2 7.4 6.6 0.7 2.8 2 0 0 2 2 2 0 C1-like domain UCR_UQCRX_QCR9 PF05365.7 EIE81374.1 - 4.8e-27 93.3 1.8 5.3e-27 93.2 1.2 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like DUF4203 PF13886.1 EIE81374.1 - 0.041 13.3 0.0 0.041 13.3 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4203) Polysacc_deac_1 PF01522.16 EIE81375.1 - 4e-08 32.9 0.0 1.1e-07 31.5 0.0 1.7 1 1 0 1 1 1 1 Polysaccharide deacetylase G-alpha PF00503.15 EIE81376.1 - 6.4e-64 216.0 0.1 7e-64 215.9 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EIE81376.1 - 1.3e-09 37.4 0.2 2.7e-09 36.5 0.1 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family DUF2985 PF11204.3 EIE81376.1 - 0.072 12.8 0.1 0.16 11.7 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2985) Ima1_N PF09779.4 EIE81377.1 - 7e-16 58.9 0.5 1e-15 58.4 0.4 1.2 1 0 0 1 1 1 1 Ima1 N-terminal domain zf-ribbon_3 PF13248.1 EIE81377.1 - 0.019 14.1 0.4 5.6 6.3 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-FPG_IleRS PF06827.9 EIE81377.1 - 0.049 13.2 0.4 9.4 5.9 0.0 2.5 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS zf-RanBP PF00641.13 EIE81377.1 - 0.07 12.2 1.3 0.07 12.2 0.9 2.0 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Zn_Tnp_IS1595 PF12760.2 EIE81377.1 - 0.083 12.7 1.2 0.083 12.7 0.8 1.8 2 0 0 2 2 2 0 Transposase zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 EIE81377.1 - 0.084 12.5 0.4 0.084 12.5 0.3 1.8 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Nudix_N_2 PF14803.1 EIE81377.1 - 0.1 12.2 1.9 0.14 11.9 0.2 1.9 2 0 0 2 2 2 0 Nudix N-terminal DZR PF12773.2 EIE81377.1 - 0.19 11.5 4.6 5.1 7.0 3.2 2.4 1 1 0 1 1 1 0 Double zinc ribbon zf-BED PF02892.10 EIE81377.1 - 0.23 11.2 4.3 4.3 7.1 0.1 2.3 1 1 1 2 2 2 0 BED zinc finger DUF1660 PF07874.6 EIE81377.1 - 0.59 10.4 4.3 3.3 8.0 0.1 2.4 1 1 0 2 2 2 0 Prophage protein (DUF1660) Prim_Zn_Ribbon PF08273.7 EIE81377.1 - 0.86 9.7 4.8 3.3 7.8 3.3 2.0 1 1 0 1 1 1 0 Zinc-binding domain of primase-helicase PHD_2 PF13831.1 EIE81377.1 - 3.1 7.1 8.5 0.99 8.7 0.3 2.9 3 0 0 3 3 3 0 PHD-finger Lipase_3 PF01764.20 EIE81378.1 - 1.8e-19 69.7 0.3 8e-19 67.6 0.2 1.9 1 1 0 1 1 1 1 Lipase (class 3) DDT PF02791.12 EIE81379.1 - 4e-08 32.8 0.1 6.9e-08 32.1 0.1 1.4 1 0 0 1 1 1 1 DDT domain WHIM3 PF15614.1 EIE81379.1 - 1.2e-05 24.9 0.0 0.00012 21.7 0.3 2.3 2 1 0 2 2 2 1 WSTF, HB1, Itc1p, MBD9 motif 3 WHIM1 PF15612.1 EIE81379.1 - 0.00026 20.7 0.3 0.0051 16.6 0.0 2.9 2 0 0 2 2 2 1 WSTF, HB1, Itc1p, MBD9 motif 1 WHIM2 PF15613.1 EIE81379.1 - 0.018 14.9 0.2 0.057 13.3 0.1 1.9 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 2 CCDC71L PF15374.1 EIE81379.1 - 0.3 10.3 19.8 0.19 11.0 7.3 2.7 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 71L SURF6 PF04935.7 EIE81380.1 - 1.6e-33 115.7 62.2 1.6e-33 115.7 43.1 2.7 2 1 0 2 2 2 1 Surfeit locus protein 6 RRP14 PF15459.1 EIE81380.1 - 2.1e-19 69.3 6.6 2.1e-19 69.3 4.5 6.9 5 2 1 6 6 6 1 60S ribosome biogenesis protein Rrp14 NUDIX PF00293.23 EIE81380.1 - 2.9e-06 26.9 0.0 5.8e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain HH_signal PF01085.13 EIE81381.1 - 0.067 12.7 0.0 0.067 12.7 0.0 1.0 1 0 0 1 1 1 0 Hedgehog amino-terminal signalling domain AA_permease PF00324.16 EIE81382.1 - 3.4e-105 352.1 40.2 2.8e-102 342.5 27.9 2.5 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EIE81382.1 - 6.7e-34 117.1 44.5 1.5e-32 112.6 30.8 2.1 1 1 0 1 1 1 1 Amino acid permease DUF3593 PF12159.3 EIE81382.1 - 0.0034 17.1 3.2 0.015 15.0 0.0 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3593) DUF2254 PF10011.4 EIE81382.1 - 0.69 8.3 3.8 3.5 6.0 0.2 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2254) PPP4R2 PF09184.6 EIE81384.1 - 2.9e-18 66.4 12.8 5.6e-18 65.4 8.9 1.5 1 1 0 1 1 1 1 PPP4R2 USP8_dimer PF08969.6 EIE81384.1 - 0.2 11.6 4.9 0.11 12.3 0.6 2.5 2 1 1 3 3 3 0 USP8 dimerisation domain TP53IP5 PF15331.1 EIE81384.1 - 0.76 9.6 5.7 1.3 8.8 3.9 1.4 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 zf-H2C2 PF09337.5 EIE81385.1 - 0.00045 19.5 0.0 0.00089 18.6 0.0 1.5 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Glyco_hydro_9 PF00759.14 EIE81385.1 - 0.2 10.4 5.3 0.32 9.8 3.7 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 BRCT PF00533.21 EIE81386.1 - 4.2e-06 26.8 0.2 8.7e-06 25.8 0.2 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain zf-RanBP PF00641.13 EIE81386.1 - 0.018 14.1 1.3 0.018 14.1 0.9 3.0 2 1 0 3 3 3 0 Zn-finger in Ran binding protein and others DUF1160 PF06648.6 EIE81386.1 - 0.031 14.0 0.1 0.067 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1160) zf-rbx1 PF12678.2 EIE81386.1 - 0.71 10.0 9.3 6.6 6.9 0.2 2.6 2 0 0 2 2 2 0 RING-H2 zinc finger zf-4CXXC_R1 PF10497.4 EIE81386.1 - 2.1 8.4 7.9 0.17 12.0 0.2 2.5 3 0 0 3 3 3 0 Zinc-finger domain of monoamine-oxidase A repressor R1 DZR PF12773.2 EIE81386.1 - 9 6.2 13.1 11 5.9 0.4 2.5 2 0 0 2 2 2 0 Double zinc ribbon CPSase_L_D2 PF02786.12 EIE81387.1 - 9.6e-113 374.6 0.1 4.4e-84 280.9 0.0 2.5 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.17 EIE81387.1 - 1.5e-47 160.3 0.0 3.2e-47 159.2 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 EIE81387.1 - 1.6e-47 161.4 0.0 3e-47 160.5 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I OTCace_N PF02729.16 EIE81387.1 - 4.8e-44 149.4 0.0 1e-43 148.4 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.14 EIE81387.1 - 1.1e-41 141.4 0.0 3.4e-41 139.8 0.0 1.9 2 0 0 2 2 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_L_chain PF00289.17 EIE81387.1 - 1.4e-41 140.9 0.0 8.5e-22 77.3 0.0 3.1 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain OTCace PF00185.19 EIE81387.1 - 1e-37 129.4 0.1 3.4e-37 127.7 0.0 2.0 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ATP-grasp_4 PF13535.1 EIE81387.1 - 1.8e-33 115.8 0.2 1.4e-22 80.3 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 EIE81387.1 - 2.2e-22 79.2 0.0 1.2e-11 43.9 0.0 3.6 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon MGS PF02142.17 EIE81387.1 - 4.8e-20 71.2 0.0 4.1e-19 68.3 0.0 2.7 3 0 0 3 3 3 1 MGS-like domain Dala_Dala_lig_C PF07478.8 EIE81387.1 - 3.3e-15 56.0 0.6 5.4e-08 32.4 0.0 2.9 2 1 1 3 3 3 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EIE81387.1 - 5.1e-14 51.9 0.1 2.6e-07 30.1 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_3 PF02655.9 EIE81387.1 - 4.5e-06 26.6 0.3 0.13 12.0 0.0 3.0 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.8 EIE81387.1 - 2.1e-05 24.0 0.1 0.00041 19.8 0.1 2.4 1 1 0 1 1 1 1 Peptidase C26 NmrA PF05368.8 EIE81387.1 - 0.0048 16.1 0.0 0.012 14.9 0.0 1.6 1 0 0 1 1 1 1 NmrA-like family zf-C2H2_4 PF13894.1 EIE81389.1 - 0.00027 21.0 12.0 0.025 14.8 0.2 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EIE81389.1 - 0.0031 17.7 19.2 0.012 15.8 0.6 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type SH3_9 PF14604.1 EIE81390.1 - 1.1e-10 40.9 0.0 1.7e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EIE81390.1 - 4.3e-05 22.8 0.0 7.1e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 SH3 domain DUF3824 PF12868.2 EIE81390.1 - 0.00013 22.9 3.8 0.00013 22.9 2.7 2.4 2 0 0 2 2 2 1 Domain of unknwon function (DUF3824) SH3_2 PF07653.12 EIE81390.1 - 0.0043 16.4 0.0 0.0088 15.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Amnionless PF14828.1 EIE81390.1 - 0.012 14.0 0.7 0.015 13.8 0.0 1.4 2 0 0 2 2 2 0 Amnionless Macoilin PF09726.4 EIE81390.1 - 0.14 10.3 23.9 0.2 9.8 16.6 1.2 1 0 0 1 1 1 0 Transmembrane protein Rifin_STEVOR PF02009.11 EIE81390.1 - 0.3 10.6 10.6 0.9 9.1 7.3 1.7 1 1 0 1 1 1 0 Rifin/stevor family SKG6 PF08693.5 EIE81390.1 - 0.89 8.9 7.5 0.092 12.0 1.6 2.2 2 0 0 2 2 2 0 Transmembrane alpha-helix domain CD99L2 PF12301.3 EIE81390.1 - 1 9.0 12.6 2.6 7.7 8.4 2.0 1 1 0 1 1 1 0 CD99 antigen like protein 2 RCR PF12273.3 EIE81390.1 - 1.2 9.7 15.7 0.85 10.1 4.8 2.7 2 1 1 3 3 3 0 Chitin synthesis regulation, resistance to Congo red Plasmodium_Vir PF05795.6 EIE81390.1 - 1.9 7.5 20.8 14 4.7 14.4 2.0 1 1 0 1 1 1 0 Plasmodium vivax Vir protein Clr2 PF10383.4 EIE81391.1 - 0.076 13.0 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Transcription-silencing protein Clr2 F-box-like PF12937.2 EIE81392.1 - 0.00028 20.5 0.2 0.00059 19.5 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIE81392.1 - 0.0039 16.7 2.4 0.014 15.0 1.6 1.9 1 1 0 1 1 1 1 F-box domain Abhydrolase_6 PF12697.2 EIE81393.1 - 6.6e-18 65.4 0.0 1e-17 64.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIE81393.1 - 1.3e-08 34.6 0.0 4.2e-08 33.0 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIE81393.1 - 3.1e-06 26.9 0.0 2.8e-05 23.9 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioredoxin PF00085.15 EIE81394.1 - 0.0023 17.5 0.1 0.0032 17.1 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin PHD PF00628.24 EIE81395.1 - 9.2e-10 38.0 8.2 1.5e-09 37.4 5.7 1.3 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 EIE81395.1 - 0.0026 17.8 0.8 0.0043 17.1 0.6 1.3 1 0 0 1 1 1 1 PHD-like zinc-binding domain PHD_2 PF13831.1 EIE81395.1 - 0.012 14.8 3.3 0.027 13.7 2.3 1.7 1 0 0 1 1 1 0 PHD-finger zf-HC5HC2H_2 PF13832.1 EIE81395.1 - 0.036 14.0 0.6 0.055 13.4 0.4 1.3 1 0 0 1 1 1 0 PHD-zinc-finger like domain Glyco_hydro_15 PF00723.16 EIE81396.1 - 4e-71 239.9 0.0 5e-71 239.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 KilA-N PF04383.8 EIE81396.1 - 0.02 14.4 0.0 0.071 12.7 0.0 1.9 2 0 0 2 2 2 0 KilA-N domain Fasciclin PF02469.17 EIE81397.1 - 1.3e-12 47.8 0.2 2.3e-12 47.0 0.2 1.4 1 0 0 1 1 1 1 Fasciclin domain ECH PF00378.15 EIE81398.1 - 7.5e-76 254.4 1.3 8.8e-76 254.2 0.9 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 EIE81398.1 - 0.00027 20.7 0.2 0.0081 15.9 0.0 2.4 2 1 0 2 2 2 1 Peptidase family S49 DUF1640 PF07798.6 EIE81399.1 - 5.5e-51 173.1 10.8 6.1e-51 172.9 7.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) TPR_MLP1_2 PF07926.7 EIE81399.1 - 0.0033 17.1 5.3 0.0033 17.1 3.7 2.1 1 1 0 2 2 2 1 TPR/MLP1/MLP2-like protein DivIC PF04977.10 EIE81399.1 - 0.011 15.1 17.4 0.24 10.9 0.5 3.2 2 1 1 3 3 3 0 Septum formation initiator CENP-Q PF13094.1 EIE81399.1 - 0.035 14.1 8.8 0.052 13.5 6.1 1.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit ADIP PF11559.3 EIE81399.1 - 0.1 12.5 12.4 0.72 9.7 1.6 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF1664 PF07889.7 EIE81399.1 - 0.17 11.6 8.2 1.6 8.5 1.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) YfhO PF09586.5 EIE81399.1 - 0.18 9.7 1.1 0.28 9.1 0.8 1.2 1 0 0 1 1 1 0 Bacterial membrane protein YfhO RasGAP PF00616.14 EIE81399.1 - 0.2 11.3 4.1 0.14 11.7 1.8 1.4 1 1 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase FlaC_arch PF05377.6 EIE81399.1 - 0.2 11.5 10.9 1.1 9.2 1.3 2.8 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) DNA_topoisoIV PF00521.15 EIE81399.1 - 0.3 9.9 10.1 0.37 9.5 7.0 1.1 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A DUF1184 PF06683.6 EIE81399.1 - 0.34 10.4 3.3 0.084 12.5 0.3 1.5 2 0 0 2 2 1 0 Protein of unknown function (DUF1184) DUF342 PF03961.8 EIE81399.1 - 0.41 8.9 15.0 3.8 5.8 10.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF342) Syntaxin-6_N PF09177.6 EIE81399.1 - 0.44 10.9 10.5 1.8 8.9 2.3 2.5 1 1 1 2 2 2 0 Syntaxin 6, N-terminal HALZ PF02183.13 EIE81399.1 - 0.46 10.2 12.1 4.1 7.2 1.3 3.2 2 1 0 2 2 2 0 Homeobox associated leucine zipper USP8_interact PF08941.5 EIE81399.1 - 0.51 9.6 6.2 1 8.6 0.5 2.2 2 0 0 2 2 2 0 USP8 interacting COG5 PF10392.4 EIE81399.1 - 0.55 10.1 11.9 8 6.4 1.0 3.1 1 1 1 2 2 2 0 Golgi transport complex subunit 5 TBPIP PF07106.8 EIE81399.1 - 0.63 9.5 16.3 0.17 11.3 3.9 2.2 1 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Prefoldin_2 PF01920.15 EIE81399.1 - 0.84 9.4 19.6 1.3 8.7 3.4 2.9 2 1 0 2 2 2 0 Prefoldin subunit DUF2408 PF10303.4 EIE81399.1 - 1.2 9.2 11.2 8.5 6.5 7.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) Matrilin_ccoil PF10393.4 EIE81399.1 - 1.3 8.4 4.5 0.92 8.9 1.1 2.3 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF972 PF06156.8 EIE81399.1 - 1.3 9.3 12.1 1.1 9.6 2.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) AAA_13 PF13166.1 EIE81399.1 - 1.4 7.2 15.6 0.16 10.3 4.3 2.0 1 1 0 2 2 2 0 AAA domain IncA PF04156.9 EIE81399.1 - 1.5 8.3 16.7 7.5 6.1 11.6 1.9 1 1 0 1 1 1 0 IncA protein ZapA PF05164.8 EIE81399.1 - 1.7 8.6 8.8 2.7 8.0 0.4 2.6 2 1 0 2 2 2 0 Cell division protein ZapA FlxA PF14282.1 EIE81399.1 - 1.8 8.5 13.4 5.5 6.9 1.1 2.2 2 0 0 2 2 2 0 FlxA-like protein UPF0449 PF15136.1 EIE81399.1 - 2.1 8.6 10.6 5.3 7.3 1.9 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 GreA_GreB_N PF03449.10 EIE81399.1 - 2.1 8.4 14.0 20 5.3 6.4 3.2 1 1 1 2 2 2 0 Transcription elongation factor, N-terminal Ax_dynein_light PF10211.4 EIE81399.1 - 2.6 7.8 17.5 1.4 8.6 3.7 2.1 1 1 1 2 2 2 0 Axonemal dynein light chain DUF2730 PF10805.3 EIE81399.1 - 3.3 7.4 10.5 1.1 9.0 1.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) DegQ PF08181.6 EIE81399.1 - 3.6 7.3 11.6 12 5.7 0.4 3.4 3 0 0 3 3 3 0 DegQ (SacQ) family DUF1451 PF07295.6 EIE81399.1 - 4.3 7.1 7.8 7.5 6.3 5.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1451) DUF4337 PF14235.1 EIE81399.1 - 4.3 7.1 9.5 4.5 7.0 0.9 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4337) CENP-H PF05837.7 EIE81399.1 - 5.5 7.2 12.9 13 6.0 4.0 2.5 2 1 0 2 2 2 0 Centromere protein H (CENP-H) PCRF PF03462.13 EIE81399.1 - 5.8 6.6 8.7 1.7 8.3 0.4 2.9 2 1 1 3 3 3 0 PCRF domain Spc7 PF08317.6 EIE81399.1 - 9 4.8 17.4 27 3.2 2.7 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein MARVEL PF01284.18 EIE81400.1 - 7.8e-11 41.9 3.0 1.3e-10 41.3 2.1 1.3 1 0 0 1 1 1 1 Membrane-associating domain Mem_trans PF03547.13 EIE81400.1 - 0.0039 15.5 0.0 0.0051 15.1 0.0 1.1 1 0 0 1 1 1 1 Membrane transport protein Gln-synt_C PF00120.19 EIE81401.1 - 9.5e-64 215.0 0.0 1.2e-63 214.6 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain MFS_1 PF07690.11 EIE81402.1 - 3.6e-38 131.1 20.3 5.1e-38 130.6 14.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily ESSS PF10183.4 EIE81402.1 - 0.0098 16.2 0.3 0.033 14.6 0.2 1.9 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) CS PF04969.11 EIE81403.1 - 3.9e-09 36.9 0.2 1.9e-08 34.7 0.0 2.3 2 0 0 2 2 2 1 CS domain CoA_transf_3 PF02515.12 EIE81404.1 - 8.4e-69 230.6 0.0 1.1e-68 230.3 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III Kelch_5 PF13854.1 EIE81405.1 - 1.5e-19 69.5 1.6 2.9e-05 23.8 0.0 4.3 5 0 0 5 5 5 3 Kelch motif Kelch_6 PF13964.1 EIE81405.1 - 4e-15 55.2 1.4 6.9e-05 22.8 0.0 4.1 3 1 1 4 4 4 3 Kelch motif Kelch_3 PF13415.1 EIE81405.1 - 4.3e-15 55.3 1.7 7.9e-10 38.6 0.0 4.6 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_4 PF13418.1 EIE81405.1 - 6.6e-15 54.6 0.9 3.4e-06 26.7 0.0 4.0 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_1 PF01344.20 EIE81405.1 - 1.8e-11 43.4 0.1 0.0014 18.1 0.0 3.5 3 0 0 3 3 3 3 Kelch motif Kelch_2 PF07646.10 EIE81405.1 - 4.2e-10 38.9 0.6 0.029 14.1 0.0 4.0 4 0 0 4 4 4 3 Kelch motif BTB PF00651.26 EIE81405.1 - 7.5e-05 22.6 0.0 0.00014 21.7 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Cyt-b5 PF00173.23 EIE81406.1 - 2e-25 88.3 0.1 2.5e-25 88.0 0.1 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ALMT PF11744.3 EIE81408.1 - 4.9e-22 78.1 9.3 5e-22 78.1 5.7 1.5 1 1 0 1 1 1 1 Aluminium activated malate transporter FUSC_2 PF13515.1 EIE81408.1 - 1.3e-11 44.5 15.1 2.5e-11 43.6 10.4 1.5 1 0 0 1 1 1 1 Fusaric acid resistance protein-like FUSC PF04632.7 EIE81408.1 - 1.6e-06 26.8 10.1 2.3e-06 26.3 7.0 1.2 1 0 0 1 1 1 1 Fusaric acid resistance protein family DUF2678 PF10856.3 EIE81408.1 - 0.17 11.5 3.2 0.35 10.6 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2678) FUSC-like PF12805.2 EIE81408.1 - 0.35 9.7 2.5 0.41 9.5 0.4 2.3 1 1 0 1 1 1 0 FUSC-like inner membrane protein yccS DUF2422 PF10337.4 EIE81408.1 - 5.8 5.5 20.2 1.1 7.9 3.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2422) Rhodanese PF00581.15 EIE81409.1 - 4.6e-27 94.6 0.0 3.3e-12 46.7 0.0 2.6 2 1 1 3 3 3 3 Rhodanese-like domain PTS_IIB PF02302.12 EIE81409.1 - 0.05 14.0 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 PTS system, Lactose/Cellobiose specific IIB subunit Ribosomal_L7Ae PF01248.21 EIE81410.1 - 2.7e-26 90.8 0.0 3.3e-26 90.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 EIE81410.1 - 0.0039 17.0 0.0 0.0044 16.8 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.1 EIE81410.1 - 0.024 14.4 0.0 0.03 14.0 0.0 1.2 1 0 0 1 1 1 0 PELOTA RNA binding domain Dicty_REP PF05086.7 EIE81411.1 - 7.4 4.1 8.6 9.5 3.8 5.9 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF4625 PF15418.1 EIE81412.1 - 0.0041 17.2 0.1 0.0058 16.7 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4625) EVI2A PF05399.6 EIE81412.1 - 0.14 11.3 9.1 0.29 10.3 6.3 1.6 1 1 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) ETC_C1_NDUFA5 PF04716.9 EIE81413.1 - 3.2e-24 84.1 1.3 6.7e-24 83.1 0.9 1.5 1 0 0 1 1 1 1 ETC complex I subunit conserved region Metallophos_2 PF12850.2 EIE81414.1 - 1.3e-12 47.8 0.0 1.5e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EIE81414.1 - 0.087 12.2 0.3 0.12 11.8 0.2 1.2 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase Topoisom_bac PF01131.15 EIE81415.1 - 8.6e-80 268.5 0.0 6.6e-59 199.7 0.0 2.5 1 1 1 2 2 2 2 DNA topoisomerase Toprim PF01751.17 EIE81415.1 - 8.7e-14 51.3 0.0 2.1e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 Toprim domain SRF-TF PF00319.13 EIE81416.1 - 1.6e-22 78.4 0.2 2.6e-22 77.8 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Med15 PF09606.5 EIE81416.1 - 1.5 6.9 37.0 1.8 6.6 25.7 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DIL PF01843.14 EIE81417.1 - 1.5e-20 73.0 6.0 1.5e-20 73.0 4.2 2.3 2 0 0 2 2 2 1 DIL domain Ank PF00023.25 EIE81417.1 - 1.1e-07 31.2 0.0 3e-07 29.9 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.2 EIE81417.1 - 4.7e-06 26.8 0.0 1.2e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EIE81417.1 - 2.6e-05 24.0 0.1 0.00013 21.8 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 EIE81417.1 - 0.0022 18.1 0.0 0.0043 17.2 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 EIE81417.1 - 0.0079 16.6 0.0 0.019 15.4 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 EIE81418.1 - 6.3e-41 138.0 9.0 1.7e-13 50.6 0.0 4.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.25 EIE81418.1 - 2.8e-33 112.0 1.1 2.4e-07 30.2 0.0 4.7 4 0 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.2 EIE81418.1 - 4.7e-32 110.1 1.8 1.5e-17 63.6 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EIE81418.1 - 1.3e-28 98.3 4.2 1.6e-09 37.7 0.1 5.0 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIE81418.1 - 9.4e-24 81.1 2.4 1.4e-05 24.8 0.0 4.8 4 0 0 4 4 4 4 Ankyrin repeat FYVE PF01363.16 EIE81418.1 - 1.1e-17 63.6 8.7 2e-17 62.8 6.1 1.4 1 0 0 1 1 1 1 FYVE zinc finger SSP160 PF06933.6 EIE81418.1 - 2.9 5.7 15.2 4.1 5.2 10.6 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 zf-RING_5 PF14634.1 EIE81420.1 - 0.012 15.2 2.6 0.022 14.4 1.8 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Pkinase PF00069.20 EIE81422.1 - 7.9e-07 28.4 0.1 1.2e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain AlcCBM31 PF11606.3 EIE81422.1 - 0.008 16.1 0.0 0.012 15.5 0.0 1.4 1 1 0 1 1 1 1 Family 31 carbohydrate binding protein Pkinase_Tyr PF07714.12 EIE81422.1 - 0.0086 15.1 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EIE81423.1 - 5e-32 111.0 0.1 1.8e-31 109.2 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE81423.1 - 1.9e-11 43.5 0.0 4.8e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE81423.1 - 0.022 13.7 0.1 0.043 12.7 0.1 1.5 1 1 0 1 1 1 0 Kinase-like Tyrosinase PF00264.15 EIE81423.1 - 2.2 8.4 6.4 0.48 10.5 1.5 1.8 1 1 1 2 2 2 0 Common central domain of tyrosinase Glyco_hydro_15 PF00723.16 EIE81424.1 - 4.8e-05 22.1 0.0 4.9e-05 22.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 ING PF12998.2 EIE81425.1 - 1.5e-14 54.1 7.4 2.1e-14 53.6 5.1 1.2 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 EIE81425.1 - 1.5e-08 34.2 8.4 2.4e-08 33.5 5.9 1.3 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 EIE81425.1 - 0.031 14.3 0.3 0.072 13.2 0.2 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain ECR1_N PF14382.1 EIE81425.1 - 0.069 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Exosome complex exonuclease RRP4 N-terminal region PHD_2 PF13831.1 EIE81425.1 - 0.17 11.2 4.6 0.44 9.8 3.2 1.8 1 0 0 1 1 1 0 PHD-finger FCH PF00611.18 EIE81425.1 - 0.48 10.6 5.0 2.7 8.2 0.3 3.0 3 0 0 3 3 3 0 Fes/CIP4, and EFC/F-BAR homology domain DUF919 PF06034.6 EIE81425.1 - 1.8 8.2 5.6 5.1 6.8 0.4 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) DnaJ PF00226.26 EIE81426.1 - 6.6e-27 93.0 4.7 1.5e-26 91.8 3.2 1.6 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EIE81426.1 - 1.9e-22 78.9 0.3 1.9e-21 75.7 0.0 2.2 2 0 0 2 2 2 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EIE81426.1 - 5.1e-09 36.0 20.9 9e-09 35.2 14.5 1.4 1 0 0 1 1 1 1 DnaJ central domain zf-C3HC4_3 PF13920.1 EIE81426.1 - 2.3 7.9 7.0 1.3 8.7 2.7 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Peptidase_S8 PF00082.17 EIE81427.1 - 1.3e-42 145.9 6.0 4.8e-42 144.0 3.2 2.2 1 1 1 2 2 2 1 Subtilase family P_proprotein PF01483.15 EIE81427.1 - 9.5e-27 92.6 0.3 2.1e-26 91.5 0.2 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain Pex14_N PF04695.8 EIE81427.1 - 0.075 13.0 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region zf-RVT PF13966.1 EIE81428.1 - 4.7e-07 30.0 1.1 8.6e-05 22.7 0.6 2.8 2 0 0 2 2 2 2 zinc-binding in reverse transcriptase TFIID-18kDa PF02269.11 EIE81428.1 - 0.048 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit RVT_3 PF13456.1 EIE81428.1 - 0.081 12.7 0.1 0.19 11.5 0.1 1.6 1 0 0 1 1 1 0 Reverse transcriptase-like DDE_3 PF13358.1 EIE81429.1 - 0.00013 21.7 0.0 0.00024 20.8 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease 4F5 PF04419.9 EIE81430.1 - 1.9e-07 31.6 15.1 1.9e-06 28.4 10.4 2.0 1 1 0 1 1 1 1 4F5 protein family DUF2514 PF10721.4 EIE81430.1 - 0.12 12.0 4.7 0.12 12.0 3.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Rrp15p PF07890.7 EIE81430.1 - 0.35 10.9 4.3 0.36 10.8 2.9 1.0 1 0 0 1 1 1 0 Rrp15p Pkinase PF00069.20 EIE81431.1 - 7.4e-56 189.1 0.0 1.4e-55 188.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE81431.1 - 1.4e-24 86.5 0.0 4.1e-24 85.0 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE81431.1 - 5.2e-05 22.3 0.0 0.0085 15.0 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 EIE81431.1 - 0.0064 15.5 0.0 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIE81431.1 - 0.08 12.6 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF995 PF06191.7 EIE81431.1 - 0.086 12.2 0.1 0.14 11.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF995) ATP-synt_C PF00137.16 EIE81432.1 - 1.8e-30 104.6 30.8 8.2e-19 67.2 7.8 2.1 2 0 0 2 2 2 2 ATP synthase subunit C TCR_zetazeta PF11628.3 EIE81432.1 - 0.52 9.8 5.7 1.1 8.8 0.7 2.4 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 zeta chain PT-VENN PF04829.8 EIE81432.1 - 2.2 7.8 4.2 3 7.4 2.1 1.8 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif Aa_trans PF01490.13 EIE81433.1 - 4.2e-30 104.5 11.9 5e-30 104.2 8.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.1 EIE81433.1 - 8e-08 31.2 19.5 1.1e-07 30.8 13.5 1.2 1 0 0 1 1 1 1 Amino acid permease Spore_permease PF03845.8 EIE81433.1 - 2.5e-05 23.0 11.9 6.7e-05 21.6 8.2 1.6 1 1 0 1 1 1 1 Spore germination protein DUF373 PF04123.8 EIE81433.1 - 0.57 9.1 5.9 1.4 7.8 3.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF373) IF3_N PF05198.11 EIE81434.1 - 5.4 7.0 8.7 12 5.8 2.4 2.5 2 0 0 2 2 2 0 Translation initiation factor IF-3, N-terminal domain Brix PF04427.13 EIE81435.1 - 4.4e-26 91.7 0.8 2.2e-22 79.6 0.2 2.2 1 1 1 2 2 2 2 Brix domain PfkB PF00294.19 EIE81436.1 - 2.6e-58 197.5 0.3 3.1e-58 197.2 0.2 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Peripla_BP_2 PF01497.13 EIE81436.1 - 0.051 12.6 0.0 0.094 11.8 0.0 1.4 1 0 0 1 1 1 0 Periplasmic binding protein HMA PF00403.21 EIE81437.1 - 1.3e-54 182.1 5.5 8.8e-13 48.1 0.1 4.7 4 0 0 4 4 4 4 Heavy-metal-associated domain E1-E2_ATPase PF00122.15 EIE81437.1 - 6.1e-48 162.8 0.9 6.1e-48 162.8 0.6 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EIE81437.1 - 4.3e-41 141.6 0.1 7e-41 140.9 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EIE81437.1 - 9.1e-16 58.5 0.0 2.4e-15 57.2 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EIE81437.1 - 2.3e-06 27.3 2.0 0.0078 15.8 1.1 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase SH3_9 PF14604.1 EIE81438.1 - 3.5e-34 116.1 4.9 1.2e-14 53.6 0.2 3.3 3 0 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.23 EIE81438.1 - 9.6e-32 108.1 6.6 1.3e-11 43.7 0.4 3.4 3 0 0 3 3 3 3 SH3 domain SH3_2 PF07653.12 EIE81438.1 - 1.1e-28 98.5 1.2 2.3e-10 39.7 0.0 3.3 3 0 0 3 3 3 3 Variant SH3 domain Exotox-A_target PF09102.5 EIE81438.1 - 0.11 12.0 0.2 0.26 10.7 0.2 1.5 1 0 0 1 1 1 0 Exotoxin A, targeting GPP34 PF05719.6 EIE81439.1 - 2.7e-61 207.2 0.0 3.4e-61 206.8 0.0 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) MIR PF02815.14 EIE81440.1 - 8.5e-13 48.2 0.8 1.2e-12 47.7 0.6 1.2 1 0 0 1 1 1 1 MIR domain ERG2_Sigma1R PF04622.7 EIE81441.1 - 1.6e-78 262.9 0.1 1.7e-78 262.8 0.1 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein SPATIAL PF15256.1 EIE81442.1 - 0.0075 16.3 1.2 0.013 15.6 0.6 1.6 1 1 0 1 1 1 1 SPATIAL ECH_C PF13766.1 EIE81443.1 - 5.2e-33 113.6 1.8 2.8e-32 111.3 0.0 2.6 3 0 0 3 3 3 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 EIE81443.1 - 3.6e-28 98.3 1.9 9.3e-28 96.9 0.0 2.3 2 1 0 2 2 2 1 Enoyl-CoA hydratase/isomerase family DUF448 PF04296.8 EIE81444.1 - 0.021 14.4 0.0 0.032 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF448) DUF940 PF06082.6 EIE81445.1 - 0.24 9.8 1.3 0.25 9.8 0.9 1.0 1 0 0 1 1 1 0 Bacterial putative lipoprotein (DUF940) DHHW PF14286.1 EIE81445.1 - 0.53 9.5 2.8 0.61 9.3 1.9 1.0 1 0 0 1 1 1 0 DHHW protein RRP7 PF12923.2 EIE81445.1 - 4.8 7.2 8.8 91 3.0 6.1 2.0 1 1 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) Tubulin PF00091.20 EIE81446.1 - 2.1e-71 240.2 0.0 3.7e-71 239.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EIE81446.1 - 1.4e-47 160.8 0.0 2.1e-47 160.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EIE81446.1 - 1.2e-05 25.3 0.6 1.9e-05 24.6 0.0 1.7 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Prenyltrans PF00432.16 EIE81447.1 - 2.1e-13 49.6 9.8 0.00073 19.0 0.0 5.3 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EIE81447.1 - 1.8e-11 44.4 0.0 9.8e-08 32.3 0.0 3.0 2 1 1 3 3 3 2 Prenyltransferase-like DNA_mis_repair PF01119.14 EIE81448.1 - 3.5e-26 91.0 0.0 1.4e-25 89.0 0.0 2.1 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain MutL_C PF08676.6 EIE81448.1 - 8.4e-19 67.5 0.1 2.8e-18 65.9 0.1 1.9 1 0 0 1 1 1 1 MutL C terminal dimerisation domain HATPase_c_3 PF13589.1 EIE81449.1 - 2.1e-11 43.6 0.2 2.4e-11 43.4 0.1 1.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EIE81449.1 - 1.5e-09 37.5 0.1 1.8e-09 37.2 0.1 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 EIE81449.1 - 0.014 15.1 0.1 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain PX PF00787.19 EIE81451.1 - 3.3e-11 42.9 5.4 6.4e-11 42.0 3.7 1.5 1 0 0 1 1 1 1 PX domain PB1 PF00564.19 EIE81451.1 - 0.0012 18.5 0.1 0.0054 16.3 0.0 2.1 2 0 0 2 2 2 1 PB1 domain HIT PF01230.18 EIE81451.1 - 0.017 15.6 0.6 8.2 7.0 0.1 2.6 2 0 0 2 2 2 0 HIT domain SET PF00856.23 EIE81452.1 - 8.5e-06 26.1 0.0 3.6e-05 24.1 0.0 2.2 1 1 0 1 1 1 1 SET domain RXT2_N PF08595.6 EIE81452.1 - 0.42 10.3 4.5 15 5.3 1.3 2.5 2 0 0 2 2 2 0 RXT2-like, N-terminal DUF4611 PF15387.1 EIE81452.1 - 1.3 9.2 9.7 0.17 12.0 1.9 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) ZZ PF00569.12 EIE81453.1 - 9e-16 57.1 38.7 8.3e-08 31.6 5.0 3.5 3 0 0 3 3 3 3 Zinc finger, ZZ type DUF445 PF04286.7 EIE81453.1 - 2 7.8 12.4 0.11 12.0 4.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF445) DKCLD PF08068.7 EIE81454.1 - 6.6e-31 106.0 0.2 7.6e-30 102.6 0.1 2.4 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.13 EIE81454.1 - 9.6e-24 84.2 0.2 6.6e-21 75.0 0.1 3.5 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 EIE81454.1 - 1.2e-19 69.7 1.5 2.4e-19 68.8 1.1 1.5 1 0 0 1 1 1 1 PUA domain RNA_polI_A34 PF08208.6 EIE81454.1 - 0.25 10.9 22.1 0.39 10.3 15.3 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Coatomer_WDAD PF04053.9 EIE81455.1 - 2.5e-171 570.3 0.0 8.1e-170 565.3 0.0 2.3 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.27 EIE81455.1 - 3.3e-54 178.9 1.5 2e-11 43.3 0.0 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat BBS2_Mid PF14783.1 EIE81455.1 - 6e-05 22.7 0.0 3.4 7.4 0.0 5.0 5 1 1 6 6 6 2 Ciliary BBSome complex subunit 2, middle region TPR_8 PF13181.1 EIE81455.1 - 0.092 12.5 0.0 1 9.3 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Clathrin PF00637.15 EIE81455.1 - 0.1 12.2 0.2 5.9 6.4 0.0 2.3 1 1 1 2 2 2 0 Region in Clathrin and VPS NAD_binding_1 PF00175.16 EIE81456.1 - 1.9e-28 99.2 0.0 3.4e-28 98.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EIE81456.1 - 9.9e-24 83.3 0.0 1.4e-23 82.8 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EIE81456.1 - 2.3e-08 34.0 0.0 3.9e-07 30.0 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EIE81456.1 - 0.00011 22.1 0.0 0.00058 19.8 0.0 1.9 2 0 0 2 2 2 1 Siderophore-interacting FAD-binding domain Velvet PF11754.3 EIE81458.1 - 1.6e-08 34.4 0.1 5.9e-08 32.5 0.1 2.0 1 1 0 1 1 1 1 Velvet factor E1_DerP2_DerF2 PF02221.10 EIE81459.1 - 7.4e-21 74.7 0.1 9.3e-21 74.4 0.1 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 EIE81459.1 - 0.0002 21.3 0.0 0.00025 21.0 0.0 1.3 1 0 0 1 1 1 1 ML-like domain Alph_Pro_TM PF09608.5 EIE81459.1 - 0.033 13.7 0.0 0.054 13.0 0.0 1.3 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) TPR_19 PF14559.1 EIE81461.1 - 1.1e-13 51.3 5.7 8.6e-09 35.6 0.3 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 EIE81461.1 - 1.1e-10 41.0 1.3 1.8e-06 27.5 0.1 1.9 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 EIE81461.1 - 1.1e-09 37.5 0.8 5.4e-05 22.7 0.0 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EIE81461.1 - 4.7e-08 32.3 0.1 0.0012 18.3 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EIE81461.1 - 8.6e-08 32.1 0.3 4.5e-05 23.7 0.0 2.5 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 EIE81461.1 - 2.6e-07 30.2 0.3 0.0015 18.6 0.1 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 EIE81461.1 - 1.1e-05 25.9 0.6 2.6e-05 24.7 0.1 1.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 EIE81461.1 - 0.00012 21.6 0.4 0.0025 17.4 0.0 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 EIE81461.1 - 0.00016 21.9 0.2 0.0006 20.0 0.0 2.1 2 1 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 EIE81461.1 - 0.00086 19.4 0.1 0.0014 18.7 0.1 1.4 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EIE81461.1 - 0.0027 17.5 0.0 0.0036 17.1 0.0 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.1 EIE81461.1 - 0.004 16.8 0.0 0.051 13.3 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_20 PF14561.1 EIE81461.1 - 0.0081 16.2 1.5 0.021 14.9 0.7 1.8 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.1 EIE81461.1 - 0.0097 15.8 1.6 0.014 15.2 0.2 1.9 2 1 0 2 2 1 1 Tetratricopeptide repeat TPR_15 PF13429.1 EIE81461.1 - 0.015 14.3 0.3 0.02 13.9 0.2 1.3 1 1 0 1 1 1 0 Tetratricopeptide repeat NARP1 PF12569.3 EIE81461.1 - 0.02 13.6 2.2 0.02 13.6 1.5 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Clathrin PF00637.15 EIE81461.1 - 0.046 13.3 0.5 0.13 11.8 0.2 1.7 1 1 1 2 2 2 0 Region in Clathrin and VPS TPR_21 PF09976.4 EIE81461.1 - 0.13 12.1 2.3 0.16 11.8 1.6 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat CDC37_N PF03234.9 EIE81461.1 - 0.16 12.2 4.0 0.18 12.1 2.8 1.0 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding RRM_3 PF08777.6 EIE81461.1 - 0.19 11.5 1.8 0.21 11.4 0.8 1.4 1 1 0 1 1 1 0 RNA binding motif FliT PF05400.8 EIE81461.1 - 0.75 10.2 6.0 1.7 9.0 4.1 1.6 1 1 0 1 1 1 0 Flagellar protein FliT Chitin_synth_2 PF03142.10 EIE81462.1 - 5.1e-271 899.6 0.0 5.1e-271 899.6 0.0 1.3 2 0 0 2 2 2 1 Chitin synthase Glyco_tranf_2_3 PF13641.1 EIE81462.1 - 9.7e-19 68.0 0.0 4.7e-16 59.2 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EIE81462.1 - 1.1e-16 61.0 4.7 4e-16 59.2 2.9 2.3 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.1 EIE81462.1 - 8.8e-06 25.1 0.1 0.0023 17.2 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EIE81462.1 - 0.00029 20.5 0.0 0.0092 15.6 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 E1-E2_ATPase PF00122.15 EIE81463.1 - 1.4e-56 191.0 8.7 1.1e-55 188.2 4.9 2.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EIE81463.1 - 1.6e-28 100.6 0.2 3e-28 99.6 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EIE81463.1 - 1e-14 55.1 0.0 2.2e-14 54.0 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EIE81463.1 - 1.2e-13 50.2 0.0 4.7e-13 48.3 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase_C PF00689.16 EIE81463.1 - 0.0012 18.3 7.4 0.0012 18.3 5.1 2.6 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase_3 PF08282.7 EIE81463.1 - 0.012 15.1 0.1 0.034 13.7 0.0 1.7 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EIE81463.1 - 0.068 13.1 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit Perilipin PF03036.11 EIE81464.1 - 2.4e-13 49.6 18.6 2.6e-08 33.1 0.3 2.6 1 1 1 2 2 2 2 Perilipin family Apolipoprotein PF01442.13 EIE81464.1 - 0.00048 19.7 13.8 0.081 12.4 0.1 2.8 2 1 0 2 2 2 2 Apolipoprotein A1/A4/E domain Selenoprotein_S PF06936.6 EIE81464.1 - 0.083 12.4 0.7 0.24 10.8 0.5 1.8 1 0 0 1 1 1 0 Selenoprotein S (SelS) GLTSCR1 PF15249.1 EIE81464.1 - 0.57 10.2 4.2 5.2 7.2 0.1 3.2 3 1 0 3 3 3 0 Glioma tumor suppressor candidate region ATP-synt PF00231.14 EIE81465.1 - 8.8e-70 235.3 11.3 1e-69 235.1 7.9 1.0 1 0 0 1 1 1 1 ATP synthase HDA2-3 PF11496.3 EIE81467.1 - 0.023 13.5 0.1 5.9 5.6 0.0 2.3 2 0 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 CwfJ_C_1 PF04677.10 EIE81468.1 - 1.2e-29 102.4 0.1 4.8e-29 100.4 0.1 1.9 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 EIE81468.1 - 1.1e-24 86.7 0.5 6.6e-23 81.0 0.1 2.6 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 zf-CCHC_2 PF13696.1 EIE81468.1 - 2.2e-11 43.0 15.6 1e-07 31.2 2.1 2.9 2 1 1 3 3 3 2 Zinc knuckle zf-CCHC PF00098.18 EIE81468.1 - 2e-08 33.7 13.3 0.00014 21.6 0.7 3.3 3 0 0 3 3 3 2 Zinc knuckle zf-CCHC_4 PF14392.1 EIE81468.1 - 0.053 13.1 3.7 3.7 7.3 0.1 2.6 2 0 0 2 2 2 0 Zinc knuckle HIT PF01230.18 EIE81468.1 - 0.076 13.5 0.0 0.19 12.2 0.0 1.6 1 0 0 1 1 1 0 HIT domain zf-CCHC_3 PF13917.1 EIE81468.1 - 0.22 11.2 5.2 52 3.6 3.6 2.5 1 1 0 1 1 1 0 Zinc knuckle zf-HIT PF04438.11 EIE81468.1 - 0.23 11.1 6.5 1.8 8.2 0.4 2.6 2 0 0 2 2 2 0 HIT zinc finger CPSF_A PF03178.10 EIE81469.1 - 9e-93 310.8 0.0 1.8e-91 306.6 0.0 2.3 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.4 EIE81469.1 - 3.7e-72 243.0 0.0 6e-72 242.3 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Coatomer_WDAD PF04053.9 EIE81469.1 - 0.26 10.0 0.0 0.73 8.5 0.0 1.6 2 0 0 2 2 2 0 Coatomer WD associated region UQ_con PF00179.21 EIE81470.1 - 1.3e-49 167.2 0.0 1.4e-49 167.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme CRC_subunit PF08624.5 EIE81471.1 - 2.9e-39 134.1 0.4 1e-38 132.3 0.0 1.9 2 0 0 2 2 2 1 Chromatin remodelling complex Rsc7/Swp82 subunit Ribosomal_S27 PF01599.14 EIE81472.1 - 5.4e-29 99.7 2.8 1.1e-28 98.8 2.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S27a ubiquitin PF00240.18 EIE81472.1 - 5.2e-16 57.7 0.0 1.2e-15 56.6 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.3 EIE81472.1 - 5.1e-07 29.2 0.0 9.7e-07 28.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like IBR PF01485.16 EIE81472.1 - 0.012 15.4 0.8 0.019 14.8 0.5 1.4 1 0 0 1 1 1 0 IBR domain Telomere_Sde2 PF13019.1 EIE81472.1 - 0.024 14.3 0.3 0.035 13.7 0.1 1.5 1 1 0 1 1 1 0 Telomere stability and silencing Dishevelled PF02377.10 EIE81473.1 - 0.026 14.7 1.2 0.038 14.1 0.8 1.2 1 0 0 1 1 1 0 Dishevelled specific domain CBP4 PF07960.6 EIE81473.1 - 0.045 13.3 1.1 0.074 12.6 0.8 1.5 1 1 0 1 1 1 0 CBP4 Rho_Binding PF08912.6 EIE81473.1 - 0.12 12.6 6.1 0.18 12.1 4.2 1.2 1 0 0 1 1 1 0 Rho Binding MgtE PF01769.11 EIE81474.1 - 6.7e-40 136.4 24.1 7.3e-21 74.8 2.9 3.4 3 1 1 4 4 4 2 Divalent cation transporter ArfGap PF01412.13 EIE81475.1 - 3.1e-42 143.0 1.3 3.1e-42 143.0 0.9 1.7 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf Cytochrome_CBB3 PF13442.1 EIE81475.1 - 0.0059 16.7 0.3 0.21 11.7 0.2 2.3 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III LGFP PF08310.6 EIE81475.1 - 0.035 13.7 0.2 0.064 12.8 0.2 1.4 1 0 0 1 1 1 0 LGFP repeat SQS_PSY PF00494.14 EIE81476.1 - 2.2e-42 145.1 0.0 3e-42 144.7 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase DUF4468 PF14730.1 EIE81477.1 - 0.0058 16.3 0.3 0.0091 15.6 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4468) with TBP-like fold DUF4625 PF15418.1 EIE81477.1 - 0.043 13.9 0.0 0.066 13.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4625) FimP PF09766.4 EIE81478.1 - 4.7e-29 101.5 12.0 6.6e-29 101.0 8.3 1.1 1 0 0 1 1 1 1 Fms-interacting protein DUF904 PF06005.7 EIE81478.1 - 0.63 10.3 10.1 0.12 12.6 1.7 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF904) Peptidase_M28 PF04389.12 EIE81479.1 - 1.1e-31 109.9 0.0 1.8e-31 109.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EIE81479.1 - 3.1e-06 26.8 0.0 4.9e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Nicastrin PF05450.10 EIE81479.1 - 1.5e-05 24.3 0.1 0.0052 16.0 0.0 2.5 2 0 0 2 2 2 2 Nicastrin Rep_3 PF01051.16 EIE81479.1 - 0.0019 17.8 0.4 0.0044 16.6 0.1 1.7 2 0 0 2 2 2 1 Initiator Replication protein HMG_box PF00505.14 EIE81481.1 - 1.5e-13 50.7 0.2 1.8e-13 50.5 0.1 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EIE81481.1 - 2.4e-10 40.6 0.0 3e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.1 EIE81481.1 - 5.3e-05 22.9 0.5 6.7e-05 22.6 0.4 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box 5 Pectate_lyase PF03211.8 EIE81482.1 - 0.024 14.0 0.6 0.037 13.4 0.4 1.2 1 0 0 1 1 1 0 Pectate lyase TMEM171 PF15471.1 EIE81482.1 - 0.073 11.8 0.3 0.095 11.4 0.2 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 PBP1_TM PF14812.1 EIE81482.1 - 3.3 8.0 6.5 8.6 6.7 4.5 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ldh_1_N PF00056.18 EIE81483.1 - 3.7e-33 114.3 2.9 5.8e-33 113.6 2.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 EIE81483.1 - 3.7e-29 101.6 0.1 8.1e-29 100.5 0.0 1.5 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain UDPG_MGDP_dh_N PF03721.9 EIE81483.1 - 3.7e-05 23.1 1.6 0.00047 19.5 1.0 2.2 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DAO PF01266.19 EIE81483.1 - 0.00078 18.4 0.1 0.0012 17.8 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Shikimate_DH PF01488.15 EIE81483.1 - 0.0011 19.0 0.6 0.0021 18.1 0.4 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase OCD_Mu_crystall PF02423.10 EIE81483.1 - 0.0034 16.1 0.9 0.0054 15.5 0.7 1.3 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family 3HCDH_N PF02737.13 EIE81483.1 - 0.0055 16.3 0.6 0.011 15.4 0.4 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.16 EIE81483.1 - 0.0061 16.3 0.1 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 ThiF family Pyr_redox PF00070.22 EIE81483.1 - 0.023 15.0 0.1 0.069 13.5 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EIE81483.1 - 0.032 14.2 0.2 0.063 13.2 0.2 1.6 1 0 0 1 1 1 0 TrkA-N domain CoA_binding PF02629.14 EIE81483.1 - 0.038 14.4 0.4 0.15 12.5 0.2 2.0 2 1 0 2 2 2 0 CoA binding domain NAD_Gly3P_dh_N PF01210.18 EIE81483.1 - 0.043 13.5 0.2 0.7 9.6 0.0 2.4 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox_3 PF13738.1 EIE81483.1 - 0.056 13.5 0.4 0.1 12.6 0.3 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 EIE81483.1 - 0.068 12.6 1.0 0.15 11.4 0.7 1.7 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.12 EIE81483.1 - 0.07 13.5 3.7 0.072 13.5 1.1 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent KH_1 PF00013.24 EIE81485.1 - 2.4e-43 145.5 10.4 7.6e-17 60.7 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EIE81485.1 - 1.1e-34 117.4 14.9 2.5e-12 46.1 1.5 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 EIE81485.1 - 4.1e-12 45.4 7.1 0.00026 20.4 0.2 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 EIE81485.1 - 1.1e-07 31.3 7.9 0.00073 19.1 0.2 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 EIE81485.1 - 0.0026 17.5 6.0 2 8.2 0.3 3.4 3 0 0 3 3 3 2 NusA-like KH domain DUF1264 PF06884.6 EIE81487.1 - 3e-63 212.2 0.0 3.6e-63 212.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) APG6 PF04111.7 EIE81488.1 - 0.0047 16.0 0.3 0.0093 15.0 0.2 1.4 1 0 0 1 1 1 1 Autophagy protein Apg6 MAGSP PF03082.9 EIE81488.1 - 0.019 14.3 1.7 0.029 13.7 1.1 1.4 1 1 0 1 1 1 0 Male accessory gland secretory protein SseC PF04888.7 EIE81488.1 - 0.045 13.0 0.3 0.054 12.8 0.2 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family DivIC PF04977.10 EIE81488.1 - 0.064 12.7 3.1 0.13 11.7 2.1 1.5 1 0 0 1 1 1 0 Septum formation initiator TMF_TATA_bd PF12325.3 EIE81488.1 - 0.093 12.4 2.6 0.39 10.4 0.3 2.8 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding V_ATPase_I PF01496.14 EIE81488.1 - 0.12 10.2 0.5 0.15 9.9 0.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FYVE_2 PF02318.11 EIE81488.1 - 0.17 11.7 2.3 0.58 10.0 1.6 1.9 1 0 0 1 1 1 0 FYVE-type zinc finger DUF2681 PF10883.3 EIE81488.1 - 0.17 12.0 3.3 0.43 10.8 2.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Sed5p PF11416.3 EIE81488.1 - 0.19 11.2 2.8 9.1 5.8 0.3 2.7 2 0 0 2 2 2 0 Integral membrane protein Sed5p WD40 PF00400.27 EIE81490.1 - 2e-48 160.6 12.8 1.7e-09 37.1 0.1 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 EIE81490.1 - 9.1e-11 40.5 2.1 0.0018 16.4 0.0 4.2 2 1 2 4 4 4 4 Nucleoporin Nup120/160 F-box-like PF12937.2 EIE81490.1 - 9.3e-06 25.2 0.2 1.7e-05 24.4 0.2 1.4 1 0 0 1 1 1 1 F-box-like BBS2_Mid PF14783.1 EIE81490.1 - 7.3e-05 22.5 0.3 2.4 7.9 0.0 3.7 1 1 1 3 3 3 1 Ciliary BBSome complex subunit 2, middle region F-box PF00646.28 EIE81490.1 - 0.0011 18.5 0.4 0.0019 17.7 0.2 1.3 1 0 0 1 1 1 1 F-box domain PQQ_3 PF13570.1 EIE81490.1 - 0.0024 18.1 0.0 1.2 9.5 0.0 3.7 4 0 0 4 4 4 1 PQQ-like domain DUF1513 PF07433.6 EIE81490.1 - 0.0041 16.0 0.1 0.16 10.8 0.0 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF1513) PQQ_2 PF13360.1 EIE81490.1 - 0.006 16.0 0.2 0.62 9.4 0.2 2.5 1 1 0 1 1 1 1 PQQ-like domain Nucleoporin_N PF08801.6 EIE81490.1 - 0.015 14.0 3.5 1.2 7.8 0.0 3.6 2 2 2 4 4 4 0 Nup133 N terminal like DUF4451 PF14616.1 EIE81491.1 - 1.5e-27 95.8 11.5 4.3e-27 94.3 8.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4451) zf-A20 PF01754.11 EIE81491.1 - 3.6 7.2 5.1 1.2 8.7 0.5 2.3 2 0 0 2 2 2 0 A20-like zinc finger Methyltransf_23 PF13489.1 EIE81493.1 - 9.9e-12 44.8 0.0 1.8e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIE81493.1 - 3.7e-11 43.3 0.0 7e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EIE81493.1 - 4.8e-08 32.2 0.0 4.1e-06 25.9 0.0 2.9 3 0 0 3 3 3 1 Putative methyltransferase Methyltransf_25 PF13649.1 EIE81493.1 - 2.8e-07 30.8 0.0 5.8e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIE81493.1 - 4.8e-07 29.4 0.0 1.2e-06 28.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIE81493.1 - 5.6e-07 29.9 0.0 1.2e-06 28.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIE81493.1 - 2.1e-06 28.3 0.0 1.5e-05 25.4 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIE81493.1 - 3.3e-05 23.1 0.0 6.7e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.14 EIE81493.1 - 0.015 15.3 0.0 0.04 13.8 0.0 1.7 2 0 0 2 2 2 0 FtsJ-like methyltransferase Methyltransf_8 PF05148.10 EIE81493.1 - 0.015 14.9 0.0 0.051 13.1 0.0 1.8 1 1 0 1 1 1 0 Hypothetical methyltransferase RrnaAD PF00398.15 EIE81493.1 - 0.029 13.3 0.0 0.068 12.1 0.0 1.6 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase Methyltransf_9 PF08003.6 EIE81493.1 - 0.038 12.6 0.0 0.069 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) MSP7_C PF12948.2 EIE81493.1 - 0.062 13.5 0.7 0.19 11.9 0.5 1.7 1 0 0 1 1 1 0 MSP7-like protein C-terminal domain CMAS PF02353.15 EIE81493.1 - 0.067 12.2 0.0 0.17 10.9 0.0 1.6 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase PCMT PF01135.14 EIE81493.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 EIE81493.1 - 0.16 11.9 0.0 1.4 8.9 0.0 2.3 2 1 0 2 2 1 0 Methyltransferase domain GST_N_3 PF13417.1 EIE81494.1 - 2.3e-12 46.9 0.0 4.9e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIE81494.1 - 2.4e-07 30.6 0.0 4.8e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EIE81494.1 - 3.7e-07 30.0 0.1 9.7e-06 25.4 0.0 2.7 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EIE81494.1 - 5.5e-07 29.3 0.0 1.6e-06 27.8 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EIE81494.1 - 3.3e-05 23.9 0.0 6.9e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EIE81494.1 - 0.0037 17.7 0.0 0.011 16.1 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Ribosomal_S17e PF00833.13 EIE81495.1 - 4.3e-59 197.6 0.3 4.9e-59 197.4 0.2 1.0 1 0 0 1 1 1 1 Ribosomal S17 Cupin_8 PF13621.1 EIE81496.1 - 2.4e-58 197.6 0.3 4.4e-58 196.7 0.2 1.5 1 0 0 1 1 1 1 Cupin-like domain ABC1 PF03109.11 EIE81496.1 - 7.2e-22 77.5 0.0 1.4e-19 70.1 0.0 2.5 1 1 0 1 1 1 1 ABC1 family RIO1 PF01163.17 EIE81496.1 - 0.00012 21.5 0.0 0.00028 20.2 0.0 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EIE81496.1 - 0.023 14.4 0.8 0.19 11.4 0.5 2.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family JmjC PF02373.17 EIE81496.1 - 0.04 14.1 0.2 4.4 7.5 0.0 3.3 3 0 0 3 3 3 0 JmjC domain, hydroxylase DUF3489 PF11994.3 EIE81496.1 - 0.05 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3489) GATA PF00320.22 EIE81497.1 - 1.6e-17 62.5 3.9 2.7e-17 61.7 2.7 1.4 1 0 0 1 1 1 1 GATA zinc finger DZR PF12773.2 EIE81497.1 - 4 7.3 7.5 9.7 6.1 1.9 2.2 1 1 1 2 2 2 0 Double zinc ribbon Peptidase_A22B PF04258.8 EIE81498.1 - 1.6e-77 260.8 14.5 2.1e-77 260.5 10.0 1.1 1 0 0 1 1 1 1 Signal peptide peptidase DUF1119 PF06550.6 EIE81498.1 - 1.1e-05 24.7 1.7 1.1e-05 24.7 1.2 1.9 3 0 0 3 3 3 1 Protein of unknown function (DUF1119) Zip PF02535.17 EIE81498.1 - 0.03 13.3 0.0 0.064 12.2 0.0 1.6 1 0 0 1 1 1 0 ZIP Zinc transporter AAA_11 PF13086.1 EIE81498.1 - 0.23 10.9 3.4 0.38 10.2 2.3 1.3 1 0 0 1 1 1 0 AAA domain OAD_gamma PF04277.8 EIE81498.1 - 0.3 11.4 3.2 4.1 7.8 1.9 2.5 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Pex24p PF06398.6 EIE81498.1 - 0.66 8.7 5.6 0.1 11.3 0.4 2.0 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin EF-hand_4 PF12763.2 EIE81499.1 - 3.5e-33 113.4 0.1 1.1e-13 50.8 0.0 4.1 4 0 0 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 EIE81499.1 - 4.8e-08 33.0 0.0 0.02 15.0 0.0 3.9 2 1 0 2 2 2 2 EF-hand domain pair UBA PF00627.26 EIE81499.1 - 7.7e-06 25.6 0.0 1.8e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain RGS PF00615.14 EIE81500.1 - 3.5e-28 98.0 0.2 1.1e-27 96.4 0.0 2.0 2 0 0 2 2 2 1 Regulator of G protein signaling domain DEP PF00610.16 EIE81500.1 - 9.2e-11 41.3 0.0 7.8e-05 22.3 0.0 3.0 2 1 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Glyco_hydro_20 PF00728.17 EIE81502.1 - 5.9e-94 315.0 0.1 7.5e-94 314.7 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 EIE81502.1 - 1e-19 71.4 0.1 2.1e-19 70.4 0.0 1.5 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 EIE81502.1 - 3e-08 34.2 0.3 4.7e-08 33.6 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 DUF2508 PF10704.4 EIE81503.1 - 0.12 12.6 0.1 0.15 12.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2508) DTW PF03942.10 EIE81504.1 - 2.4e-27 95.4 0.0 4.4e-27 94.6 0.0 1.4 1 1 0 1 1 1 1 DTW domain zf-B_box PF00643.19 EIE81504.1 - 0.41 10.5 4.4 0.8 9.6 3.1 1.5 1 0 0 1 1 1 0 B-box zinc finger CBM_21 PF03370.8 EIE81505.1 - 4.3e-25 87.8 2.8 7.9e-25 87.0 2.0 1.4 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit CBM_25 PF03423.8 EIE81505.1 - 0.0017 18.3 0.2 0.0042 17.1 0.1 1.7 1 0 0 1 1 1 1 Carbohydrate binding domain (family 25) ECIST_Cterm PF14784.1 EIE81505.1 - 0.051 13.5 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 C-terminal domain of the ECSIT protein G6B PF15096.1 EIE81506.1 - 0.047 13.1 0.1 0.096 12.1 0.0 1.6 1 0 0 1 1 1 0 G6B family Homeobox_KN PF05920.6 EIE81507.1 - 1.6e-18 66.0 0.2 3.1e-18 65.2 0.1 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 EIE81507.1 - 3.4e-07 29.7 0.2 8.9e-07 28.4 0.1 1.7 1 0 0 1 1 1 1 Homeobox domain Myc_N PF01056.13 EIE81507.1 - 0.0026 16.9 0.7 0.0039 16.3 0.5 1.3 1 0 0 1 1 1 1 Myc amino-terminal region Homez PF11569.3 EIE81507.1 - 0.0062 15.5 0.0 0.012 14.6 0.0 1.5 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Tom37_C PF11801.3 EIE81507.1 - 0.01 15.7 0.5 0.01 15.7 0.3 1.4 2 0 0 2 2 2 0 Tom37 C-terminal domain PBP1_TM PF14812.1 EIE81507.1 - 0.84 9.9 4.9 0.28 11.4 0.9 2.1 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NT5C PF06941.7 EIE81508.1 - 1.3e-12 47.6 2.9 1.6e-11 44.0 2.0 2.0 1 1 0 1 1 1 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) HAD_2 PF13419.1 EIE81508.1 - 0.0023 18.1 0.2 0.0048 17.1 0.1 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase DUF929 PF06053.6 EIE81508.1 - 0.01 14.9 0.0 0.015 14.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF929) DUF3657 PF12394.3 EIE81508.1 - 0.033 14.2 1.2 0.14 12.2 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3657) TMP-TENI PF02581.12 EIE81508.1 - 0.046 12.8 0.0 0.072 12.1 0.0 1.3 1 0 0 1 1 1 0 Thiamine monophosphate synthase/TENI Hydrolase PF00702.21 EIE81508.1 - 0.089 13.1 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Pkinase PF00069.20 EIE81509.1 - 1.2e-73 247.5 0.0 2.3e-73 246.5 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE81509.1 - 4.8e-39 134.0 0.0 8.2e-39 133.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE81509.1 - 1.5e-05 24.1 0.0 2.9e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EIE81509.1 - 0.00061 19.5 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EIE81509.1 - 0.0049 16.2 0.1 0.01 15.1 0.1 1.5 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 EIE81509.1 - 0.032 13.3 2.2 0.059 12.4 0.3 2.2 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF883 PF05957.8 EIE81510.1 - 0.045 14.1 5.6 0.17 12.3 0.3 3.0 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) MgsA_C PF12002.3 EIE81510.1 - 0.064 12.9 0.5 0.22 11.1 0.0 1.9 2 0 0 2 2 2 0 MgsA AAA+ ATPase C terminal CsgE PF10627.4 EIE81510.1 - 0.075 12.8 0.1 0.21 11.4 0.1 1.7 1 0 0 1 1 1 0 Curli assembly protein CsgE Tape_meas_lam_C PF09718.5 EIE81510.1 - 1.4 8.8 6.9 1.3 8.9 1.5 2.7 3 0 0 3 3 3 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Pyr_redox_2 PF07992.9 EIE81511.1 - 3.5e-26 92.3 0.0 1.9e-25 89.9 0.0 2.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EIE81511.1 - 3.8e-12 46.4 2.0 1.1e-11 44.9 0.1 2.7 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EIE81511.1 - 8.3e-07 29.2 0.0 0.01 15.9 0.0 2.7 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIE81511.1 - 0.11 10.9 1.3 0.72 8.2 0.0 2.3 1 1 1 2 2 2 0 HI0933-like protein NAD_binding_9 PF13454.1 EIE81511.1 - 0.19 11.4 0.9 33 4.2 0.6 3.3 2 1 0 2 2 2 0 FAD-NAD(P)-binding Pex19 PF04614.7 EIE81512.1 - 3.8e-61 206.8 25.3 3.8e-61 206.8 17.5 2.0 1 1 1 2 2 2 1 Pex19 protein family SpoVAD PF07451.6 EIE81512.1 - 0.019 13.4 0.9 0.034 12.6 0.6 1.4 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) DUF2428 PF10350.4 EIE81512.1 - 0.022 13.8 0.2 0.088 11.8 0.0 1.9 2 0 0 2 2 2 0 Putative death-receptor fusion protein (DUF2428) DUF445 PF04286.7 EIE81512.1 - 0.032 13.7 11.7 0.21 11.0 4.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF445) GlutR_dimer PF00745.15 EIE81512.1 - 0.071 13.0 7.5 1.3 8.9 0.1 4.0 2 1 1 4 4 4 0 Glutamyl-tRNAGlu reductase, dimerisation domain Host_attach PF10116.4 EIE81512.1 - 0.43 10.8 6.5 0.43 10.8 0.5 2.9 2 1 1 3 3 3 0 Protein required for attachment to host cells DUF4061 PF13270.1 EIE81512.1 - 0.56 10.3 9.4 0.12 12.5 0.9 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4061) SPX PF03105.14 EIE81512.1 - 2.4 7.8 13.8 7.1 6.3 9.5 1.6 1 1 0 1 1 1 0 SPX domain COG2 PF06148.6 EIE81512.1 - 6.9 6.5 8.5 2.5 7.9 0.3 3.0 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1617 PF07761.7 EIE81515.1 - 0.041 13.9 1.9 0.06 13.3 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1617) ABC_tran_2 PF12848.2 EIE81515.1 - 0.073 12.9 1.3 3 7.7 0.4 2.5 1 1 1 2 2 2 0 ABC transporter Phage_Mu_Gam PF07352.7 EIE81515.1 - 1.1 8.7 6.0 1.2 8.6 2.7 2.3 1 1 0 1 1 1 0 Bacteriophage Mu Gam like protein Ribosomal_L30 PF00327.15 EIE81516.1 - 4.3e-19 67.8 0.9 9.8e-19 66.6 0.6 1.7 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.7 EIE81516.1 - 5.3e-17 61.5 17.9 2.6e-16 59.4 5.0 2.4 2 0 0 2 2 2 2 Ribosomal L30 N-terminal domain ChlI PF13541.1 EIE81518.1 - 0.096 12.2 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Subunit ChlI of Mg-chelatase SLA_LP_auto_ag PF05889.8 EIE81518.1 - 0.11 10.9 0.0 0.16 10.4 0.0 1.2 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) UPF0122 PF04297.9 EIE81518.1 - 0.21 11.6 1.9 1.4 8.9 0.1 2.6 3 0 0 3 3 3 0 Putative helix-turn-helix protein, YlxM / p13 like Chlam_vir PF05475.6 EIE81518.1 - 0.29 10.1 2.5 0.31 10.0 1.1 1.4 1 1 0 1 1 1 0 Chlamydia virulence protein PGP3-D HEAT_2 PF13646.1 EIE81520.1 - 3.7e-09 36.7 6.4 0.71 10.1 0.1 7.8 8 1 1 9 9 9 3 HEAT repeats HEAT PF02985.17 EIE81520.1 - 3.7e-09 35.8 10.9 0.74 10.0 0.0 10.9 12 0 0 12 12 12 2 HEAT repeat Vac14_Fab1_bd PF12755.2 EIE81520.1 - 0.0034 17.7 0.0 1.8 9.0 0.0 3.9 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 EIE81520.1 - 0.018 15.5 4.1 22 5.6 0.1 6.5 6 1 2 8 8 8 0 HEAT-like repeat GATA PF00320.22 EIE81521.1 - 1.8 7.9 22.5 0.12 11.7 7.2 3.4 2 1 0 2 2 2 0 GATA zinc finger Pik1 PF11522.3 EIE81522.1 - 3.5e-09 36.2 0.0 2.4e-08 33.6 0.0 2.5 2 0 0 2 2 2 1 Yeast phosphatidylinositol-4-OH kinase Pik1 PI3Ka PF00613.15 EIE81522.1 - 1.4e-05 24.3 0.1 3.2e-05 23.1 0.1 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) SH3_9 PF14604.1 EIE81523.1 - 2e-07 30.4 0.0 4.5e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EIE81523.1 - 2.1e-07 30.2 0.1 4e-07 29.3 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EIE81523.1 - 6.2e-05 22.4 0.1 0.00013 21.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SPT16 PF08644.6 EIE81524.1 - 3.6e-53 179.4 1.8 1.3e-52 177.6 0.0 2.8 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 EIE81524.1 - 1e-40 138.9 0.9 1e-40 138.9 0.6 2.3 2 0 0 2 2 2 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.19 EIE81524.1 - 8.3e-27 94.1 0.0 1.8e-26 92.9 0.0 1.6 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.7 EIE81524.1 - 3e-21 75.1 0.1 1.1e-20 73.3 0.1 2.1 1 0 0 1 1 1 1 Histone chaperone Rttp106-like DHC_N1 PF08385.7 EIE81525.1 - 1.3e-188 628.0 14.8 1.3e-188 628.0 10.2 3.7 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 Dynein_heavy PF03028.10 EIE81525.1 - 1.1e-180 602.2 0.3 1.9e-178 594.8 0.2 2.6 1 1 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor DHC_N2 PF08393.8 EIE81525.1 - 1e-135 452.4 8.6 1e-135 452.4 6.0 5.5 7 0 0 7 7 6 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 EIE81525.1 - 4e-83 278.4 0.0 1.3e-82 276.8 0.0 1.9 2 0 0 2 2 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 EIE81525.1 - 3.1e-47 160.8 0.1 8.1e-46 156.1 0.0 2.9 2 1 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.2 EIE81525.1 - 2.2e-46 157.5 0.1 8.6e-46 155.6 0.1 2.1 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 MT PF12777.2 EIE81525.1 - 2e-41 141.8 6.9 8.4e-41 139.8 4.8 2.1 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 EIE81525.1 - 2.3e-28 98.6 0.0 1e-11 44.7 0.0 6.2 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) AAA_7 PF12775.2 EIE81525.1 - 1.4e-16 60.4 0.0 3.7e-16 59.0 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region D3 AAA_22 PF13401.1 EIE81525.1 - 2.4e-14 53.6 0.0 0.02 15.0 0.0 5.4 4 0 0 4 4 4 3 AAA domain AAA PF00004.24 EIE81525.1 - 4.4e-12 46.3 0.0 0.016 15.4 0.0 5.0 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EIE81525.1 - 1.4e-11 44.4 0.1 0.011 15.5 0.0 5.5 5 0 0 5 5 5 3 AAA domain AAA_16 PF13191.1 EIE81525.1 - 1.2e-09 38.4 0.1 0.079 12.9 0.1 5.9 4 1 1 5 5 5 2 AAA ATPase domain AAA_17 PF13207.1 EIE81525.1 - 1.8e-09 38.4 1.8 0.16 12.7 0.0 6.6 5 0 0 5 5 5 2 AAA domain T2SE PF00437.15 EIE81525.1 - 5.5e-07 28.7 0.1 0.073 11.9 0.0 4.3 4 0 0 4 4 3 2 Type II/IV secretion system protein AAA_29 PF13555.1 EIE81525.1 - 3.3e-06 26.5 0.0 0.5 9.9 0.0 3.6 3 0 0 3 3 3 2 P-loop containing region of AAA domain Mg_chelatase PF01078.16 EIE81525.1 - 8.3e-06 25.1 0.4 0.81 8.8 0.0 3.7 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 EIE81525.1 - 8.5e-06 26.1 0.1 0.36 11.1 0.0 4.5 3 0 0 3 3 3 1 ABC transporter AAA_19 PF13245.1 EIE81525.1 - 1.4e-05 24.7 0.2 1.2 8.9 0.0 4.5 4 0 0 4 4 4 1 Part of AAA domain AAA_18 PF13238.1 EIE81525.1 - 2.2e-05 24.7 9.7 0.11 12.7 0.0 6.1 6 0 0 6 6 5 1 AAA domain FtsK_SpoIIIE PF01580.13 EIE81525.1 - 8.1e-05 22.1 0.0 5.5 6.3 0.0 4.4 3 0 0 3 3 3 0 FtsK/SpoIIIE family IstB_IS21 PF01695.12 EIE81525.1 - 0.00019 20.9 0.5 0.22 10.9 0.0 4.2 4 0 0 4 4 4 1 IstB-like ATP binding protein DUF258 PF03193.11 EIE81525.1 - 0.0014 17.7 0.0 4 6.5 0.0 3.7 3 0 0 3 3 3 1 Protein of unknown function, DUF258 RNA_helicase PF00910.17 EIE81525.1 - 0.0015 18.6 0.0 3.3 7.9 0.0 4.8 4 0 0 4 4 4 1 RNA helicase AAA_25 PF13481.1 EIE81525.1 - 0.002 17.5 0.1 1.3 8.4 0.0 4.3 4 0 0 4 4 3 1 AAA domain MobB PF03205.9 EIE81525.1 - 0.032 13.9 0.3 19 4.9 0.0 3.6 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 EIE81525.1 - 1.5 8.1 14.4 3.6 6.9 0.0 5.5 7 0 0 7 7 7 0 AAA-like domain Fib_alpha PF08702.5 EIE81526.1 - 2 8.5 88.6 0.58 10.2 8.3 5.2 1 1 5 6 6 6 0 Fibrinogen alpha/beta chain family Reo_sigmaC PF04582.7 EIE81526.1 - 3.6 6.6 24.0 0.35 10.0 2.5 4.4 2 1 3 5 5 5 0 Reovirus sigma C capsid protein PK PF00224.16 EIE81527.1 - 4.6e-152 505.6 1.1 5.7e-152 505.3 0.7 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 EIE81527.1 - 1.2e-29 102.2 0.0 2.4e-29 101.2 0.0 1.5 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 EIE81527.1 - 0.0022 16.9 0.2 0.0065 15.3 0.1 1.7 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family CNF1 PF05785.7 EIE81527.1 - 0.08 11.8 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Rho-activating domain of cytotoxic necrotizing factor DDE_3 PF13358.1 EIE81528.1 - 3.6e-30 104.6 0.0 6.9e-30 103.7 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 EIE81528.1 - 7.9e-10 38.8 0.2 2.5e-09 37.2 0.0 1.9 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.1 EIE81528.1 - 4.1e-08 33.9 0.3 1.1e-07 32.5 0.0 1.9 2 0 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.1 EIE81528.1 - 2.9e-07 29.9 0.3 0.00013 21.5 0.0 2.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.1 EIE81528.1 - 4.6e-07 29.7 6.0 4.2e-06 26.6 0.7 3.1 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_17 PF12728.2 EIE81528.1 - 0.00012 22.2 0.3 0.14 12.4 0.2 2.6 2 0 0 2 2 2 2 Helix-turn-helix domain rve PF00665.21 EIE81528.1 - 0.00045 20.3 0.0 0.0039 17.2 0.0 2.4 2 1 1 3 3 3 1 Integrase core domain Terminase_5 PF06056.7 EIE81528.1 - 0.0013 18.2 0.2 0.011 15.2 0.0 2.5 2 1 0 2 2 2 1 Putative ATPase subunit of terminase (gpP-like) HTH_Tnp_1 PF01527.15 EIE81528.1 - 0.0055 16.6 1.7 0.0079 16.1 0.2 2.0 2 0 0 2 2 2 1 Transposase LZ_Tnp_IS481 PF13011.1 EIE81528.1 - 0.024 14.9 0.3 0.09 13.1 0.2 2.0 2 0 0 2 2 1 0 leucine-zipper of insertion element IS481 HTH_Tnp_ISL3 PF13542.1 EIE81528.1 - 0.04 13.1 0.4 0.096 11.8 0.3 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 DUF746 PF05344.6 EIE81528.1 - 0.044 13.3 0.0 0.089 12.3 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF746) Sigma70_r4_2 PF08281.7 EIE81528.1 - 0.077 12.4 0.2 0.38 10.2 0.0 2.1 2 0 0 2 2 2 0 Sigma-70, region 4 ApoO PF09769.4 EIE81529.1 - 0.055 13.1 0.0 0.25 11.0 0.0 2.0 2 0 0 2 2 2 0 Apolipoprotein O DUF1199 PF06712.6 EIE81529.1 - 0.13 12.0 2.0 7.8 6.3 0.6 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1199) DDE_3 PF13358.1 EIE81530.1 - 3.6e-30 104.6 0.0 6.9e-30 103.7 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 EIE81530.1 - 7.9e-10 38.8 0.2 2.5e-09 37.2 0.0 1.9 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.1 EIE81530.1 - 4.1e-08 33.9 0.3 1.1e-07 32.5 0.0 1.9 2 0 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.1 EIE81530.1 - 2.9e-07 29.9 0.3 0.00013 21.5 0.0 2.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.1 EIE81530.1 - 4.6e-07 29.7 6.0 4.2e-06 26.6 0.7 3.1 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_17 PF12728.2 EIE81530.1 - 0.00012 22.2 0.3 0.14 12.4 0.2 2.6 2 0 0 2 2 2 2 Helix-turn-helix domain rve PF00665.21 EIE81530.1 - 0.00045 20.3 0.0 0.0039 17.2 0.0 2.4 2 1 1 3 3 3 1 Integrase core domain Terminase_5 PF06056.7 EIE81530.1 - 0.0013 18.2 0.2 0.011 15.2 0.0 2.5 2 1 0 2 2 2 1 Putative ATPase subunit of terminase (gpP-like) HTH_Tnp_1 PF01527.15 EIE81530.1 - 0.0055 16.6 1.7 0.0079 16.1 0.2 2.0 2 0 0 2 2 2 1 Transposase LZ_Tnp_IS481 PF13011.1 EIE81530.1 - 0.024 14.9 0.3 0.09 13.1 0.2 2.0 2 0 0 2 2 1 0 leucine-zipper of insertion element IS481 HTH_Tnp_ISL3 PF13542.1 EIE81530.1 - 0.04 13.1 0.4 0.096 11.8 0.3 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 DUF746 PF05344.6 EIE81530.1 - 0.044 13.3 0.0 0.089 12.3 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF746) Sigma70_r4_2 PF08281.7 EIE81530.1 - 0.077 12.4 0.2 0.38 10.2 0.0 2.1 2 0 0 2 2 2 0 Sigma-70, region 4 GATA PF00320.22 EIE81533.1 - 4.7e-26 89.8 18.3 2.8e-14 52.1 3.3 2.7 2 0 0 2 2 2 2 GATA zinc finger DUF1752 PF08550.5 EIE81533.1 - 2.5e-11 42.9 1.4 1.5e-10 40.4 0.5 2.4 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1752) TF_Zn_Ribbon PF08271.7 EIE81533.1 - 0.13 11.5 0.2 0.13 11.5 0.1 2.6 2 1 0 2 2 2 0 TFIIB zinc-binding Zn-ribbon_8 PF09723.5 EIE81533.1 - 0.2 11.6 2.0 2.2 8.2 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain DZR PF12773.2 EIE81533.1 - 1.6 8.6 10.6 11 5.8 0.9 3.3 2 1 1 3 3 3 0 Double zinc ribbon zf-B_box PF00643.19 EIE81533.1 - 5.4 6.9 8.6 1e+02 2.9 0.1 4.1 4 0 0 4 4 4 0 B-box zinc finger EF-hand_1 PF00036.27 EIE81534.1 - 3.6e-20 69.6 2.9 2e-09 36.0 0.1 2.2 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 EIE81534.1 - 1.1e-18 67.1 1.3 1.3e-18 66.8 0.9 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 EIE81534.1 - 1.1e-17 62.4 3.2 1.4e-08 33.6 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 EIE81534.1 - 2.8e-14 51.6 1.8 2.3e-08 33.2 0.0 3.0 2 1 1 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 EIE81534.1 - 2.6e-13 49.3 6.1 3e-09 36.3 0.7 2.1 1 1 1 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EIE81534.1 - 1.9e-08 34.3 0.2 2.1e-08 34.1 0.2 1.0 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EIE81534.1 - 0.0015 18.2 0.7 0.0026 17.4 0.4 1.4 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand SRI PF08236.6 EIE81534.1 - 0.018 14.9 0.2 0.022 14.7 0.1 1.3 1 0 0 1 1 1 0 SRI (Set2 Rpb1 interacting) domain DUF1007 PF06226.8 EIE81534.1 - 0.022 14.5 0.4 0.29 10.8 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1007) UPF0154 PF03672.8 EIE81534.1 - 0.027 14.0 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) TerB PF05099.8 EIE81534.1 - 0.037 13.7 0.1 0.098 12.3 0.0 1.6 1 1 1 2 2 2 0 Tellurite resistance protein TerB GAD PF02938.9 EIE81534.1 - 0.039 14.1 0.2 0.049 13.7 0.1 1.1 1 0 0 1 1 1 0 GAD domain DUF1044 PF06296.7 EIE81534.1 - 0.049 13.4 0.2 0.061 13.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1044) FKBP_N PF01346.13 EIE81534.1 - 0.11 12.5 1.2 0.22 11.5 0.8 1.7 1 1 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase DUF533 PF04391.7 EIE81534.1 - 0.19 11.0 0.5 0.34 10.2 0.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF533) RasGEF_N PF00618.15 EIE81537.1 - 1.1e-08 35.0 0.1 1.2e-08 34.9 0.0 1.1 1 0 0 1 1 1 1 RasGEF N-terminal motif Rav1p_C PF12234.3 EIE81537.1 - 0.068 11.3 0.1 0.08 11.0 0.0 1.0 1 0 0 1 1 1 0 RAVE protein 1 C terminal RasGEF_N_2 PF14663.1 EIE81537.1 - 0.076 12.9 0.1 0.091 12.6 0.1 1.1 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain DUF684 PF05075.9 EIE81537.1 - 0.11 11.0 0.0 0.12 10.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF684) NAD_kinase PF01513.16 EIE81539.1 - 1.6e-59 201.0 0.0 1.1e-40 139.2 0.0 2.2 2 0 0 2 2 2 2 ATP-NAD kinase Ras PF00071.17 EIE81540.1 - 1.1e-62 210.1 0.2 1.4e-62 209.8 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIE81540.1 - 2.5e-22 79.6 0.1 3.6e-22 79.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIE81540.1 - 2.4e-13 49.7 0.1 3.3e-13 49.2 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EIE81540.1 - 3.6e-07 30.1 0.1 5.9e-07 29.4 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EIE81540.1 - 5.8e-06 26.4 0.0 2e-05 24.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain GTP_EFTU PF00009.22 EIE81540.1 - 4.6e-05 22.9 0.1 0.00015 21.2 0.1 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EIE81540.1 - 4.8e-05 22.6 0.1 7e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_14 PF13173.1 EIE81540.1 - 0.0007 19.4 0.1 0.0015 18.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.1 EIE81540.1 - 0.00088 18.4 0.0 0.0011 18.1 0.0 1.2 1 1 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.5 EIE81540.1 - 0.001 18.2 0.0 0.0017 17.6 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit DUF258 PF03193.11 EIE81540.1 - 0.0042 16.2 0.0 0.011 14.9 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_24 PF13479.1 EIE81540.1 - 0.0046 16.5 0.1 0.012 15.1 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_32 PF13654.1 EIE81540.1 - 0.011 14.3 0.1 0.11 11.0 0.0 2.0 1 1 1 2 2 2 0 AAA domain PduV-EutP PF10662.4 EIE81540.1 - 0.021 14.3 0.0 0.049 13.1 0.0 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.13 EIE81540.1 - 0.025 13.8 0.1 0.092 12.0 0.0 1.8 2 0 0 2 2 2 0 Ferrous iron transport protein B ABC_tran PF00005.22 EIE81540.1 - 0.036 14.3 0.1 0.054 13.7 0.0 1.5 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 EIE81540.1 - 0.052 13.5 0.2 0.095 12.6 0.2 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.1 EIE81540.1 - 0.084 12.8 0.1 0.36 10.7 0.1 2.2 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EIE81540.1 - 0.095 12.4 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Steroid_dh PF02544.11 EIE81541.1 - 6.2e-41 139.6 2.9 1.3e-40 138.6 2.0 1.5 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 EIE81541.1 - 3.5e-10 39.5 0.3 3.5e-10 39.5 0.2 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) PEMT PF04191.8 EIE81541.1 - 0.00076 19.5 0.1 0.0019 18.2 0.1 1.8 1 0 0 1 1 1 1 Phospholipid methyltransferase LRR_6 PF13516.1 EIE81542.1 - 6.7e-15 53.4 20.5 0.28 11.3 0.0 9.5 10 0 0 10 10 10 5 Leucine Rich repeat F-box-like PF12937.2 EIE81542.1 - 5.9e-13 48.3 0.1 1.9e-12 46.7 0.1 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIE81542.1 - 8.7e-08 31.6 1.7 4.3e-07 29.4 0.6 2.6 2 0 0 2 2 2 1 F-box domain LRR_1 PF00560.28 EIE81542.1 - 2.7e-07 29.6 19.8 4.3 7.7 0.0 9.7 9 1 0 9 9 9 3 Leucine Rich Repeat LRR_8 PF13855.1 EIE81542.1 - 2.9e-05 23.7 17.6 0.01 15.5 0.2 5.5 3 2 2 6 6 6 4 Leucine rich repeat LRR_7 PF13504.1 EIE81542.1 - 0.021 14.9 24.2 46 4.8 0.0 9.3 10 0 0 10 10 10 0 Leucine rich repeat Ras PF00071.17 EIE81543.1 - 4.8e-61 204.8 0.1 6e-61 204.5 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIE81543.1 - 3.2e-17 63.1 0.0 4.5e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIE81543.1 - 4.3e-13 48.8 0.0 5.3e-13 48.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EIE81543.1 - 7.4e-06 25.5 0.0 1e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EIE81543.1 - 0.029 13.5 0.0 0.032 13.3 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region FeoB_N PF02421.13 EIE81543.1 - 0.13 11.4 0.0 0.3 10.3 0.0 1.5 2 0 0 2 2 2 0 Ferrous iron transport protein B DUF972 PF06156.8 EIE81544.1 - 0.0031 17.8 2.2 0.0073 16.6 1.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF972) Shugoshin_N PF07558.6 EIE81544.1 - 0.019 14.6 5.2 0.052 13.2 3.6 1.8 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region CCDC155 PF14662.1 EIE81544.1 - 0.022 14.3 1.8 0.022 14.3 1.3 1.8 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 DivIVA PF05103.8 EIE81544.1 - 0.032 14.2 2.5 0.065 13.2 1.7 1.5 1 0 0 1 1 1 0 DivIVA protein bZIP_1 PF00170.16 EIE81544.1 - 0.24 11.3 7.1 0.76 9.7 4.4 2.3 1 1 1 2 2 2 0 bZIP transcription factor DivIC PF04977.10 EIE81544.1 - 0.56 9.7 5.0 2.2 7.8 3.5 2.0 1 1 0 1 1 1 0 Septum formation initiator DUF2536 PF10750.4 EIE81544.1 - 7.1 6.2 8.0 3.6 7.2 2.6 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2536) GCV_H PF01597.14 EIE81545.1 - 9.8e-43 144.7 0.5 1.2e-42 144.4 0.4 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein RnfC_N PF13375.1 EIE81545.1 - 0.0017 18.0 0.3 0.0024 17.5 0.2 1.2 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain Biotin_lipoyl PF00364.17 EIE81545.1 - 0.0059 16.2 0.2 0.021 14.4 0.1 1.8 1 1 1 2 2 2 1 Biotin-requiring enzyme DUF2118 PF09891.4 EIE81545.1 - 0.046 13.4 0.1 0.078 12.6 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) RNase_T PF00929.19 EIE81547.1 - 8.9e-14 52.1 0.0 1.1e-13 51.8 0.0 1.1 1 0 0 1 1 1 1 Exonuclease HobA PF12163.3 EIE81547.1 - 0.027 13.7 0.1 0.033 13.4 0.1 1.1 1 0 0 1 1 1 0 DNA replication regulator DUF2666 PF10869.3 EIE81547.1 - 0.13 12.2 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2666) Ank_2 PF12796.2 EIE81548.1 - 1.7e-21 76.3 0.3 7.3e-10 39.0 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EIE81548.1 - 7.7e-18 63.3 0.4 0.00062 19.4 0.0 5.6 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.1 EIE81548.1 - 1.1e-17 64.0 0.2 9.1e-08 32.4 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EIE81548.1 - 1.2e-16 60.3 0.4 0.0017 18.4 0.0 4.9 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIE81548.1 - 2.7e-16 58.0 0.2 0.0081 16.3 0.0 5.7 6 0 0 6 6 6 4 Ankyrin repeat DUF3510 PF12022.3 EIE81548.1 - 0.046 13.8 2.0 0.085 12.9 0.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3510) Prefoldin_2 PF01920.15 EIE81549.1 - 6.8e-21 74.0 4.4 7.9e-21 73.8 3.0 1.0 1 0 0 1 1 1 1 Prefoldin subunit Myosin_tail_1 PF01576.14 EIE81549.1 - 0.023 12.4 5.9 0.54 7.9 0.2 2.0 2 0 0 2 2 2 0 Myosin tail LCD1 PF09798.4 EIE81549.1 - 0.2 9.5 3.8 0.21 9.5 2.6 1.0 1 0 0 1 1 1 0 DNA damage checkpoint protein Mnd1 PF03962.10 EIE81549.1 - 0.45 10.1 6.8 0.86 9.2 4.7 1.4 1 1 0 1 1 1 0 Mnd1 family DivIC PF04977.10 EIE81549.1 - 1.1 8.8 4.8 1.9 8.0 0.7 2.2 2 0 0 2 2 2 0 Septum formation initiator YlqD PF11068.3 EIE81549.1 - 7.5 6.5 9.9 1 9.3 0.3 2.1 1 1 0 2 2 2 0 YlqD protein Pectinesterase PF01095.14 EIE81550.1 - 3.8e-44 150.4 5.4 7.7e-44 149.4 3.8 1.4 1 1 0 1 1 1 1 Pectinesterase Ferritin_2 PF13668.1 EIE81550.1 - 0.054 13.4 0.0 0.075 12.9 0.0 1.4 1 0 0 1 1 1 0 Ferritin-like domain DUF3419 PF11899.3 EIE81552.1 - 9.1e-128 426.1 0.2 1.2e-127 425.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.1 EIE81552.1 - 9.1e-08 31.9 0.0 3.8e-07 29.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIE81552.1 - 2.9e-07 30.1 0.0 1.6e-05 24.5 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIE81552.1 - 0.00012 22.5 0.0 0.0078 16.6 0.0 2.8 3 0 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIE81552.1 - 0.00019 20.6 0.0 0.0043 16.2 0.0 2.3 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EIE81552.1 - 0.0028 18.0 0.0 0.0094 16.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIE81552.1 - 0.12 12.7 0.0 0.45 10.9 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Homeobox PF00046.24 EIE81553.1 - 5.4e-08 32.3 2.8 1.6e-07 30.8 1.9 1.9 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EIE81553.1 - 0.00014 21.4 0.8 0.0005 19.7 0.2 2.3 2 0 0 2 2 2 1 Homeobox KN domain CDC45 PF02724.9 EIE81553.1 - 1.3 7.0 12.1 1.8 6.5 8.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Aa_trans PF01490.13 EIE81554.1 - 4.7e-86 288.8 39.9 5.6e-86 288.5 27.7 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Adeno_E3_CR2 PF02439.10 EIE81555.1 - 0.0011 18.5 3.3 0.0014 18.1 2.3 1.1 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 TMEM154 PF15102.1 EIE81555.1 - 0.0017 18.0 1.8 0.035 13.7 0.0 2.5 2 1 0 2 2 2 1 TMEM154 protein family CD34_antigen PF06365.7 EIE81555.1 - 0.0045 16.6 0.0 0.0045 16.6 0.0 2.8 3 0 0 3 3 3 1 CD34/Podocalyxin family EphA2_TM PF14575.1 EIE81555.1 - 0.0076 16.6 0.1 0.0076 16.6 0.1 2.8 2 1 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain Rifin_STEVOR PF02009.11 EIE81555.1 - 0.017 14.7 1.6 0.098 12.2 1.1 1.9 1 1 0 1 1 1 0 Rifin/stevor family TMEM190 PF15431.1 EIE81555.1 - 0.035 14.0 0.0 0.076 12.9 0.0 1.5 1 0 0 1 1 1 0 Transmembrane protein 190 Sigma_reg_N PF13800.1 EIE81555.1 - 0.086 12.8 0.1 0.086 12.8 0.0 2.5 2 0 0 2 2 2 0 Sigma factor regulator N-terminal Macoilin PF09726.4 EIE81555.1 - 0.27 9.4 25.0 0.3 9.3 17.4 1.2 1 0 0 1 1 1 0 Transmembrane protein Vpu PF00558.14 EIE81555.1 - 0.37 10.3 1.7 0.46 10.0 0.0 2.0 2 0 0 2 2 2 0 Vpu protein OPT PF03169.10 EIE81556.1 - 3.6e-175 583.9 42.9 4.1e-175 583.7 29.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Peptidase_S9 PF00326.16 EIE81558.1 - 1.8e-41 141.7 0.0 2.7e-41 141.1 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S9_N PF02897.10 EIE81558.1 - 2.2e-36 125.3 1.6 2.7e-36 125.0 1.1 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Abhydrolase_6 PF12697.2 EIE81558.1 - 0.0001 22.2 0.0 0.00014 21.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIE81558.1 - 0.026 14.0 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 EIE81558.1 - 0.038 13.5 0.0 0.068 12.7 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.15 EIE81558.1 - 0.085 12.2 0.0 0.97 8.8 0.0 2.2 1 1 0 1 1 1 0 Putative esterase zf-C2H2 PF00096.21 EIE81559.1 - 3.2e-08 33.4 9.8 1.2e-05 25.3 2.1 4.2 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIE81559.1 - 1.8e-06 27.9 7.6 6.7e-06 26.1 0.8 4.6 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EIE81559.1 - 2.2e-05 24.4 8.5 4.1e-05 23.6 1.4 4.1 4 0 0 4 4 4 2 C2H2-type zinc finger zf-met PF12874.2 EIE81559.1 - 0.00015 21.8 2.5 0.0009 19.3 0.4 3.0 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EIE81559.1 - 0.0015 18.6 4.0 0.0016 18.4 0.2 3.0 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EIE81559.1 - 3.4 7.6 6.7 2.8 7.9 0.3 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger Clat_adaptor_s PF01217.15 EIE81560.1 - 1e-21 77.1 5.8 2.1e-21 76.0 4.0 1.5 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Vps5 PF09325.5 EIE81561.1 - 5.2e-76 255.0 16.6 5.2e-76 255.0 11.5 2.1 2 0 0 2 2 2 1 Vps5 C terminal like PX PF00787.19 EIE81561.1 - 2.2e-26 91.8 1.6 2.2e-24 85.4 0.0 3.0 3 0 0 3 3 3 1 PX domain BAR_3_WASP_bdg PF10456.4 EIE81561.1 - 3.7e-05 23.0 11.7 0.0058 15.9 4.6 2.3 1 1 1 2 2 2 2 WASP-binding domain of Sorting nexin protein FlaC_arch PF05377.6 EIE81561.1 - 0.053 13.4 7.5 0.18 11.7 1.4 3.7 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Arfaptin PF06456.8 EIE81561.1 - 0.094 12.0 11.0 4 6.7 7.5 2.7 1 1 0 1 1 1 0 Arfaptin-like domain DUF3086 PF11285.3 EIE81561.1 - 0.38 9.5 12.8 0.02 13.6 3.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3086) HBS1_N PF08938.5 EIE81561.1 - 0.59 10.2 8.3 0.038 14.1 1.2 2.5 2 1 0 2 2 2 0 HBS1 N-terminus Cob_adeno_trans PF01923.13 EIE81561.1 - 6.6 6.5 10.3 0.47 10.2 1.9 2.5 2 1 1 3 3 3 0 Cobalamin adenosyltransferase Tubulin PF00091.20 EIE81562.1 - 9.1e-74 247.9 0.0 1.5e-73 247.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EIE81562.1 - 4.1e-48 162.5 0.0 7e-48 161.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EIE81562.1 - 7.3e-07 29.2 0.5 1.5e-06 28.2 0.0 1.8 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Ribosomal_60s PF00428.14 EIE81564.1 - 1.1e-25 89.8 12.2 1.3e-25 89.6 8.5 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF4611 PF15387.1 EIE81564.1 - 0.022 14.8 3.6 0.1 12.7 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Aldedh PF00171.17 EIE81564.1 - 0.023 13.0 0.1 0.028 12.7 0.1 1.1 1 0 0 1 1 1 0 Aldehyde dehydrogenase family TFIID_30kDa PF03540.8 EIE81564.1 - 0.076 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID 23-30kDa subunit Myb_DNA-bind_4 PF13837.1 EIE81565.1 - 4.2e-10 39.6 5.0 7.3e-10 38.8 3.5 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 EIE81565.1 - 2e-05 24.3 3.6 2e-05 24.3 2.5 1.8 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.2 EIE81565.1 - 6e-05 23.5 0.9 0.00017 22.1 0.6 1.8 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.4 EIE81565.1 - 0.0075 16.4 7.5 0.016 15.3 5.2 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Scm3 PF10384.4 EIE81565.1 - 0.0096 15.3 0.4 0.027 13.9 0.3 1.7 1 0 0 1 1 1 1 Centromere protein Scm3 Myb_DNA-bind_6 PF13921.1 EIE81565.1 - 0.02 14.9 0.7 0.046 13.8 0.5 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain Cep57_MT_bd PF06657.8 EIE81565.1 - 0.021 14.7 2.6 0.039 13.8 0.2 2.5 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 UBX PF00789.15 EIE81566.1 - 1.6e-15 56.9 0.0 2.6e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 UBX domain CAF-1_p150 PF11600.3 EIE81566.1 - 0.00031 20.1 6.6 0.00051 19.4 4.6 1.3 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Raftlin PF15250.1 EIE81566.1 - 0.014 13.9 0.2 0.018 13.5 0.1 1.1 1 0 0 1 1 1 0 Raftlin SPATIAL PF15256.1 EIE81566.1 - 0.077 13.0 1.7 0.12 12.4 1.1 1.2 1 0 0 1 1 1 0 SPATIAL Atrophin-1 PF03154.10 EIE81566.1 - 0.51 8.4 6.2 0.56 8.2 4.3 1.1 1 0 0 1 1 1 0 Atrophin-1 family Tom37_C PF11801.3 EIE81567.1 - 9.9e-17 61.3 3.4 9.9e-17 61.3 2.4 2.4 2 1 0 2 2 2 1 Tom37 C-terminal domain GST_C_3 PF14497.1 EIE81567.1 - 6.7e-08 32.9 0.0 1.7e-07 31.6 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EIE81567.1 - 3.7e-07 29.9 0.0 9.4e-07 28.6 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EIE81567.1 - 0.0024 17.8 0.2 0.0076 16.2 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.4 EIE81567.1 - 0.0028 17.8 0.0 0.012 15.8 0.0 2.1 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein Glyco_hydro_28 PF00295.12 EIE81568.1 - 6.9e-71 238.8 26.7 8.8e-71 238.5 18.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 DUF867 PF05908.6 EIE81568.1 - 0.035 13.1 0.1 0.066 12.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF867) DUF290 PF01060.18 EIE81568.1 - 0.043 13.8 0.9 3 7.9 0.1 2.8 2 0 0 2 2 2 0 Transthyretin-like family DUF4519 PF15012.1 EIE81569.1 - 0.11 12.4 1.3 0.23 11.3 0.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) Phytoreo_S7 PF07236.6 EIE81569.1 - 0.26 9.5 0.8 0.34 9.1 0.6 1.1 1 0 0 1 1 1 0 Phytoreovirus S7 protein DUF3402 PF11882.3 EIE81569.1 - 0.63 9.0 7.4 0.85 8.6 5.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) Asp-B-Hydro_N PF05279.6 EIE81569.1 - 0.94 9.2 7.5 1.3 8.8 5.2 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Exonuc_VII_L PF02601.10 EIE81569.1 - 1.2 8.2 4.9 1.7 7.7 3.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Herpes_DNAp_acc PF04929.7 EIE81569.1 - 4.8 6.0 7.1 8 5.3 5.0 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor PAT1 PF09770.4 EIE81569.1 - 8.4 4.4 27.2 9.9 4.2 18.9 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Fungal_trans PF04082.13 EIE81570.1 - 2.2e-39 134.9 0.4 4.8e-39 133.8 0.3 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2162 PF09930.4 EIE81571.1 - 0.14 11.3 0.1 0.17 11.0 0.0 1.1 1 0 0 1 1 1 0 Predicted transporter (DUF2162) UAA PF08449.6 EIE81572.1 - 4e-05 22.6 3.0 5.2e-05 22.3 2.1 1.1 1 0 0 1 1 1 1 UAA transporter family DUF2391 PF09622.5 EIE81572.1 - 0.036 13.2 0.2 0.044 12.9 0.2 1.2 1 0 0 1 1 1 0 Putative integral membrane protein (DUF2391) Astro_capsid PF03115.9 EIE81573.1 - 0.098 10.9 6.3 0.11 10.6 4.4 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor AAA_23 PF13476.1 EIE81573.1 - 0.12 12.7 15.2 0.15 12.3 10.5 1.1 1 0 0 1 1 1 0 AAA domain FHIPEP PF00771.15 EIE81573.1 - 0.13 10.6 3.5 0.15 10.4 2.4 1.2 1 0 0 1 1 1 0 FHIPEP family Asp-B-Hydro_N PF05279.6 EIE81573.1 - 0.19 11.5 15.5 0.23 11.2 10.7 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region SprA-related PF12118.3 EIE81573.1 - 1 8.6 11.5 1.1 8.4 8.0 1.1 1 0 0 1 1 1 0 SprA-related family Herpes_UL25 PF01499.11 EIE81573.1 - 1.1 7.4 6.3 1.5 6.9 4.3 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family RR_TM4-6 PF06459.7 EIE81573.1 - 1.1 9.0 14.9 1.5 8.6 10.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ATP-synt_10 PF05176.9 EIE81573.1 - 7.2 5.7 11.0 3.8 6.6 5.8 1.9 1 1 1 2 2 2 0 ATP10 protein AIP3 PF03915.8 EIE81574.1 - 7.1e-96 321.6 42.8 7.1e-96 321.6 29.7 1.9 3 0 0 3 3 3 1 Actin interacting protein 3 zf-C2H2_4 PF13894.1 EIE81575.1 - 3.8e-09 36.2 4.7 8.1e-05 22.6 0.2 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EIE81575.1 - 7.5e-09 35.4 8.5 0.00024 21.2 1.0 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIE81575.1 - 0.00038 20.5 10.3 0.00045 20.3 1.2 3.5 3 1 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 EIE81575.1 - 0.0012 18.6 1.3 0.057 13.3 0.1 2.7 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EIE81575.1 - 0.0017 18.4 0.1 0.0053 16.8 0.1 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EIE81575.1 - 0.0032 17.6 0.1 0.015 15.4 0.0 2.1 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.1 EIE81575.1 - 0.056 13.1 1.3 0.18 11.5 0.1 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Amelin PF05111.7 EIE81575.1 - 0.35 9.5 6.4 0.47 9.1 4.5 1.1 1 0 0 1 1 1 0 Ameloblastin precursor (Amelin) Ureidogly_hydro PF04115.7 EIE81576.1 - 3.3e-51 172.9 0.0 4.4e-51 172.4 0.0 1.1 1 0 0 1 1 1 1 Ureidoglycolate hydrolase Allantoicase PF03561.10 EIE81576.1 - 1.9e-07 30.6 0.0 3.3e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Allantoicase repeat Ribosomal_L11_N PF03946.9 EIE81577.1 - 2.2e-18 65.4 0.1 4.6e-18 64.4 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 EIE81577.1 - 1.7e-12 47.2 0.1 2.9e-12 46.5 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain IF2_N PF04760.10 EIE81577.1 - 0.055 13.1 0.1 0.4 10.3 0.0 2.3 1 1 1 2 2 2 0 Translation initiation factor IF-2, N-terminal region Nop PF01798.13 EIE81578.1 - 6.3e-60 200.8 0.0 1.3e-59 199.8 0.0 1.5 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EIE81578.1 - 5e-27 93.4 1.6 1e-26 92.4 1.1 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EIE81578.1 - 3.2e-24 84.8 1.2 3.2e-24 84.8 0.8 2.7 3 0 0 3 3 2 1 NOP5NT (NUC127) domain RNA_polI_A34 PF08208.6 EIE81578.1 - 0.022 14.4 30.8 0.037 13.7 21.4 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 RNase_H2-Ydr279 PF09468.5 EIE81578.1 - 0.038 13.1 17.9 0.079 12.1 12.4 1.6 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) DDHD PF02862.12 EIE81578.1 - 0.23 11.2 5.5 0.39 10.4 3.8 1.4 1 0 0 1 1 1 0 DDHD domain B12-binding_2 PF02607.12 EIE81578.1 - 0.48 10.4 3.9 1.8 8.6 0.1 3.1 3 0 0 3 3 3 0 B12 binding domain GAGA_bind PF06217.7 EIE81578.1 - 0.67 9.8 10.4 1.1 9.1 7.2 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family Med19 PF10278.4 EIE81578.1 - 1.6 8.4 23.0 4.4 6.9 15.8 1.9 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 CDC45 PF02724.9 EIE81578.1 - 4 5.3 16.5 5.6 4.8 11.4 1.2 1 0 0 1 1 1 0 CDC45-like protein YqfQ PF14181.1 EIE81578.1 - 4.7 7.2 23.3 13 5.8 16.1 1.8 1 0 0 1 1 1 0 YqfQ-like protein CAF-1_p150 PF11600.3 EIE81579.1 - 0.033 13.5 28.1 0.043 13.1 19.5 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal 14-3-3 PF00244.15 EIE81580.1 - 0.059 12.4 0.1 0.064 12.3 0.1 1.1 1 0 0 1 1 1 0 14-3-3 protein YolD PF08863.5 EIE81581.1 - 0.054 13.3 1.9 0.086 12.7 1.3 1.2 1 0 0 1 1 1 0 YolD-like protein BLVR PF06375.6 EIE81581.1 - 2.4 7.9 7.5 3.9 7.2 5.2 1.3 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) EamA PF00892.15 EIE81582.1 - 2.4e-18 66.3 28.8 6e-11 42.4 4.4 2.4 2 1 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 EIE81582.1 - 0.0017 18.4 26.4 0.01 16.0 4.8 3.4 3 2 1 4 4 4 2 Multidrug resistance efflux transporter DUF1129 PF06570.6 EIE81582.1 - 1.2 8.3 12.2 0.23 10.7 2.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) YtpI PF14007.1 EIE81582.1 - 2 8.3 8.4 0.68 9.8 0.4 3.1 3 0 0 3 3 3 0 YtpI-like protein tRNA-synt_2b PF00587.20 EIE81583.1 - 8.8e-30 103.5 0.1 2.5e-29 102.0 0.0 1.8 2 1 1 3 3 3 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EIE81583.1 - 5.6e-09 35.9 5.1 1.1e-08 35.1 3.5 1.5 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain 4HB_MCP_1 PF12729.2 EIE81583.1 - 0.22 10.8 3.2 0.49 9.7 2.2 1.5 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction DUF342 PF03961.8 EIE81583.1 - 0.28 9.5 2.1 0.41 9.0 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF2203 PF09969.4 EIE81583.1 - 1 9.5 4.2 5.1 7.3 0.9 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF4404 PF14357.1 EIE81585.1 - 0.074 13.4 3.6 0.17 12.2 0.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) DDE_3 PF13358.1 EIE81586.1 - 0.05 13.3 0.3 0.082 12.6 0.2 1.4 1 1 0 1 1 1 0 DDE superfamily endonuclease Metalloenzyme PF01676.13 EIE81587.1 - 1.2e-80 270.4 0.1 1.4e-80 270.2 0.1 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.8 EIE81587.1 - 5.7e-75 251.4 0.0 7.8e-75 251.0 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Phosphodiest PF01663.17 EIE81587.1 - 1.1e-06 28.2 0.0 1.8e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EIE81587.1 - 0.00022 20.5 0.0 0.00064 18.9 0.0 1.9 2 0 0 2 2 2 1 Sulfatase PglZ PF08665.7 EIE81587.1 - 0.07 12.7 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 PglZ domain Alk_phosphatase PF00245.15 EIE81587.1 - 0.081 11.5 0.0 0.75 8.4 0.0 2.0 2 0 0 2 2 2 0 Alkaline phosphatase Sel1 PF08238.7 EIE81590.1 - 2.6e-36 123.2 68.8 1.4e-05 25.5 0.2 18.9 21 0 0 21 21 21 11 Sel1 repeat TPR_16 PF13432.1 EIE81590.1 - 0.018 15.7 23.1 18 6.1 0.0 8.8 8 1 1 9 9 9 0 Tetratricopeptide repeat TPR_1 PF00515.23 EIE81590.1 - 0.05 13.2 0.0 0.05 13.2 0.0 10.5 14 0 0 14 14 14 0 Tetratricopeptide repeat TPR_11 PF13414.1 EIE81590.1 - 0.12 12.0 53.4 0.56 9.8 0.1 11.2 10 3 1 11 11 11 0 TPR repeat TPR_2 PF07719.12 EIE81590.1 - 0.78 9.8 0.0 0.78 9.8 0.0 12.3 13 0 0 13 13 13 0 Tetratricopeptide repeat COQ9 PF08511.6 EIE81591.1 - 0.13 11.7 0.1 0.16 11.4 0.1 1.3 1 1 0 1 1 1 0 COQ9 Pkinase PF00069.20 EIE81592.1 - 5.6e-17 61.7 0.5 3.5e-13 49.2 0.0 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIE81592.1 - 3.9e-05 22.8 0.0 0.029 13.4 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EIE81592.1 - 0.022 14.4 0.0 0.039 13.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 EIE81592.1 - 0.037 13.5 0.1 0.059 12.9 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase TPR_11 PF13414.1 EIE81594.1 - 2.5e-18 65.4 1.8 2.6e-14 52.6 0.2 2.3 1 1 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 EIE81594.1 - 1.6e-12 46.4 3.9 0.00014 21.2 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EIE81594.1 - 5.4e-10 38.4 0.8 0.00068 19.3 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EIE81594.1 - 6e-05 23.2 0.3 0.00076 19.7 0.1 2.6 4 0 0 4 4 3 1 Tetratricopeptide repeat Apc3 PF12895.2 EIE81594.1 - 0.00018 21.5 4.8 0.00035 20.6 3.3 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EIE81594.1 - 0.00098 19.0 0.4 3 7.8 0.5 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 EIE81594.1 - 0.003 17.6 0.3 0.017 15.2 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EIE81594.1 - 0.0064 16.3 0.2 3.1 7.7 0.0 2.7 1 1 1 2 2 2 2 Fis1 C-terminal tetratricopeptide repeat DUF3808 PF10300.4 EIE81594.1 - 0.017 13.7 0.7 0.026 13.0 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) TPR_7 PF13176.1 EIE81594.1 - 0.032 14.0 0.5 6.4 6.8 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EIE81594.1 - 0.1 13.3 0.0 0.62 10.8 0.0 2.2 2 1 0 2 2 2 0 Tetratricopeptide repeat Spc7_N PF15402.1 EIE81594.1 - 0.37 8.7 5.8 0.53 8.2 4.0 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 AAA_12 PF13087.1 EIE81596.1 - 0.0024 17.2 0.3 0.0051 16.1 0.2 1.6 1 1 0 1 1 1 1 AAA domain Astro_capsid_p PF12226.3 EIE81597.1 - 0.095 11.9 0.2 0.14 11.4 0.2 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein UPF0370 PF13980.1 EIE81597.1 - 3.4 7.5 8.3 0.32 10.8 1.8 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0370) DUF962 PF06127.6 EIE81597.1 - 5.1 7.0 8.8 5 7.0 0.6 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF962) Septin PF00735.13 EIE81598.1 - 3.4e-81 272.3 6.4 2.9e-76 256.1 4.5 3.0 1 1 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EIE81598.1 - 4.1e-07 29.9 0.0 6.4e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 EIE81598.1 - 4.4e-05 22.6 0.0 8.5e-05 21.7 0.0 1.5 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.18 EIE81598.1 - 4.8e-05 23.2 0.7 0.084 12.6 0.2 2.4 1 1 1 2 2 2 2 Dynamin family AAA_16 PF13191.1 EIE81598.1 - 0.00017 21.6 0.0 0.00024 21.1 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 EIE81598.1 - 0.00021 20.5 0.7 0.00062 18.9 0.5 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 EIE81598.1 - 0.0004 19.9 0.0 0.00061 19.3 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_17 PF13207.1 EIE81598.1 - 0.00057 20.6 0.4 0.012 16.4 0.3 2.2 1 1 0 1 1 1 1 AAA domain Miro PF08477.8 EIE81598.1 - 0.00076 19.9 0.1 0.0017 18.8 0.0 1.7 1 1 0 1 1 1 1 Miro-like protein AAA_10 PF12846.2 EIE81598.1 - 0.00089 18.7 0.3 0.0013 18.2 0.2 1.5 1 1 0 1 1 1 1 AAA-like domain GTP_EFTU PF00009.22 EIE81598.1 - 0.0019 17.6 1.3 0.67 9.3 0.1 3.0 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain T2SE PF00437.15 EIE81598.1 - 0.0026 16.6 0.1 0.0054 15.6 0.1 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein PduV-EutP PF10662.4 EIE81598.1 - 0.0047 16.4 0.0 0.0089 15.5 0.0 1.5 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation DUF87 PF01935.12 EIE81598.1 - 0.0069 16.2 0.1 0.015 15.1 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF87 AAA_22 PF13401.1 EIE81598.1 - 0.01 15.9 0.0 0.023 14.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EIE81598.1 - 0.025 14.8 0.5 0.046 14.0 0.3 1.5 1 1 0 1 1 1 0 ABC transporter IIGP PF05049.8 EIE81598.1 - 0.028 13.2 0.1 0.054 12.3 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_18 PF13238.1 EIE81598.1 - 0.028 14.7 0.3 0.053 13.8 0.2 1.7 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EIE81598.1 - 0.041 13.7 0.1 0.15 11.9 0.1 2.2 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EIE81598.1 - 0.045 13.2 0.0 0.093 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_32 PF13654.1 EIE81598.1 - 0.06 12.0 0.0 0.14 10.7 0.0 1.5 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 EIE81598.1 - 0.076 11.9 0.0 0.19 10.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DUF1542 PF07564.6 EIE81598.1 - 0.082 12.9 0.1 0.22 11.5 0.0 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) MobB PF03205.9 EIE81598.1 - 0.11 12.2 0.1 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Sigma54_activat PF00158.21 EIE81598.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.17 EIE81598.1 - 0.13 12.4 0.1 0.25 11.5 0.0 1.7 1 1 0 1 1 1 0 RNA helicase RabGAP-TBC PF00566.13 EIE81599.1 - 7.3e-24 84.4 0.9 1.3e-23 83.5 0.7 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Glyco_transf_49 PF13896.1 EIE81600.1 - 1.4e-36 126.2 1.2 4.1e-29 101.6 0.2 2.0 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glyco_tranf_2_2 PF10111.4 EIE81600.1 - 0.0012 18.0 0.1 0.0019 17.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Condensin2nSMC PF12422.3 EIE81601.1 - 0.037 13.7 0.3 0.12 12.1 0.1 1.9 1 1 1 2 2 2 0 Condensin II non structural maintenance of chromosomes subunit zf-Nse PF11789.3 EIE81603.1 - 0.16 11.5 1.7 0.82 9.2 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit DUF3038 PF11237.3 EIE81604.1 - 9.1 6.0 13.8 0.34 10.7 3.1 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF3038) MIP-T3 PF10243.4 EIE81606.1 - 1.4 7.2 51.7 0.0069 14.9 23.0 2.1 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 CDC27 PF09507.5 EIE81606.1 - 6.5 5.8 56.0 4.1 6.5 7.2 2.2 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 MFS_1 PF07690.11 EIE81608.1 - 1.3e-28 99.7 26.6 1.6e-28 99.4 18.4 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIE81608.1 - 8.5e-05 21.3 20.6 0.0021 16.6 1.7 3.0 1 1 1 3 3 3 3 Sugar (and other) transporter MFS_1_like PF12832.2 EIE81608.1 - 0.00063 19.4 3.1 0.00063 19.4 2.2 2.1 3 0 0 3 3 3 1 MFS_1 like family MscS_TM PF12794.2 EIE81608.1 - 0.0038 15.8 0.9 0.0077 14.8 0.4 1.6 1 1 0 1 1 1 1 Mechanosensitive ion channel inner membrane domain 1 MFS_2 PF13347.1 EIE81608.1 - 0.013 13.8 0.6 0.013 13.8 0.4 3.0 1 1 1 3 3 3 0 MFS/sugar transport protein DUF4257 PF14074.1 EIE81608.1 - 0.26 10.9 2.4 0.72 9.5 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4257) GPI-anchored PF10342.4 EIE81609.1 - 1.7e-13 50.8 0.1 1.7e-13 50.8 0.1 2.1 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Pex14_N PF04695.8 EIE81609.1 - 1.7 8.7 9.0 2.7 8.0 6.2 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4203 PF13886.1 EIE81611.1 - 1.5e-23 83.3 34.8 2.2e-23 82.8 24.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) SH3_1 PF00018.23 EIE81612.1 - 5.8e-37 124.8 7.0 4e-14 51.7 0.1 3.5 3 0 0 3 3 3 3 SH3 domain SHD1 PF03983.7 EIE81612.1 - 1.6e-30 104.5 0.0 3.6e-30 103.4 0.0 1.6 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_9 PF14604.1 EIE81612.1 - 4.9e-28 96.4 3.4 9.2e-10 37.9 0.0 3.5 3 0 0 3 3 3 3 Variant SH3 domain SH3_2 PF07653.12 EIE81612.1 - 1.8e-24 84.9 0.0 1.3e-09 37.3 0.0 3.4 3 0 0 3 3 3 3 Variant SH3 domain Pro_isomerase PF00160.16 EIE81613.1 - 2.6e-46 157.6 0.4 2.9e-46 157.4 0.3 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pkinase PF00069.20 EIE81615.1 - 1.4e-32 112.8 0.1 4.5e-17 62.0 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIE81615.1 - 2.2e-11 43.3 0.1 1e-07 31.3 0.1 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase Rad51 PF08423.6 EIE81616.1 - 6.1e-130 431.6 0.1 7.3e-130 431.4 0.1 1.0 1 0 0 1 1 1 1 Rad51 HHH_5 PF14520.1 EIE81616.1 - 2.7e-12 46.6 1.8 6.6e-12 45.4 0.2 2.3 1 1 1 2 2 2 1 Helix-hairpin-helix domain AAA_25 PF13481.1 EIE81616.1 - 2.8e-12 46.4 0.0 3.7e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 EIE81616.1 - 5.6e-11 42.0 0.1 8.5e-11 41.4 0.1 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 EIE81616.1 - 6.8e-05 22.0 0.5 0.00018 20.7 0.4 1.7 1 1 0 1 1 1 1 KaiC AAA_22 PF13401.1 EIE81616.1 - 0.027 14.6 0.0 0.049 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain DnaB_C PF03796.10 EIE81616.1 - 0.04 12.7 0.1 0.084 11.7 0.1 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain RGP PF03214.8 EIE81616.1 - 0.12 11.0 0.0 0.2 10.3 0.0 1.2 1 0 0 1 1 1 0 Reversibly glycosylated polypeptide PAXNEB PF05625.6 EIE81616.1 - 0.22 10.3 2.2 0.53 9.0 1.2 1.7 1 1 1 2 2 2 0 PAXNEB protein AAA_2 PF07724.9 EIE81617.1 - 4.5e-41 140.6 0.2 1.1e-40 139.3 0.2 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) UbiA PF01040.13 EIE81617.1 - 5.3e-35 120.8 14.9 7.8e-35 120.3 10.3 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family Ank PF00023.25 EIE81617.1 - 4.9e-14 51.3 0.1 5.5e-06 25.9 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 EIE81617.1 - 7e-13 48.7 0.0 5.7e-06 26.5 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EIE81617.1 - 8e-11 42.1 0.1 2.3e-07 31.1 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIE81617.1 - 1.4e-10 40.3 0.1 2.2e-05 24.2 0.0 3.3 3 0 0 3 3 2 2 Ankyrin repeat Ank_5 PF13857.1 EIE81617.1 - 6.4e-10 38.9 0.2 0.0016 18.6 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) ClpB_D2-small PF10431.4 EIE81617.1 - 1.2e-09 37.9 0.4 3.2e-09 36.5 0.0 2.0 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 EIE81617.1 - 3.1e-09 36.6 0.0 1.4e-08 34.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.24 EIE81617.1 - 1.3e-08 35.0 0.0 2.8e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EIE81617.1 - 2.2e-07 30.1 0.0 1.2e-06 27.7 0.0 2.2 3 0 0 3 3 3 1 Zeta toxin Sigma54_activat PF00158.21 EIE81617.1 - 2e-06 27.4 0.0 3.9e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_17 PF13207.1 EIE81617.1 - 5.6e-05 23.9 0.2 0.00027 21.7 0.0 2.3 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.1 EIE81617.1 - 5.7e-05 23.2 0.0 0.00032 20.8 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EIE81617.1 - 0.00058 20.1 0.2 0.0091 16.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain Torsin PF06309.6 EIE81617.1 - 0.0012 18.6 0.0 0.0031 17.3 0.0 1.6 1 0 0 1 1 1 1 Torsin AAA_33 PF13671.1 EIE81617.1 - 0.0015 18.4 0.1 0.0049 16.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.6 EIE81617.1 - 0.0018 17.8 0.0 0.011 15.3 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EIE81617.1 - 0.0039 17.2 0.0 0.011 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.12 EIE81617.1 - 0.0084 15.5 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein ABC_tran PF00005.22 EIE81617.1 - 0.012 15.9 0.0 0.041 14.1 0.0 1.9 2 0 0 2 2 1 0 ABC transporter RNA_helicase PF00910.17 EIE81617.1 - 0.03 14.5 0.0 0.088 12.9 0.0 1.8 1 0 0 1 1 1 0 RNA helicase DUF258 PF03193.11 EIE81617.1 - 0.047 12.8 0.0 0.098 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Mg_chelatase PF01078.16 EIE81617.1 - 0.19 10.8 0.1 4.6 6.3 0.1 2.9 1 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI Cullin_binding PF03556.10 EIE81618.1 - 8e-27 93.7 1.3 5.1e-25 87.8 0.1 2.1 2 0 0 2 2 2 2 Cullin binding EF-hand_7 PF13499.1 EIE81618.1 - 0.033 14.3 0.4 1.5 8.9 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain pair Cas_Csx9 PF09658.5 EIE81618.1 - 0.068 11.9 1.9 0.086 11.6 0.1 1.8 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csx9) FA_hydroxylase PF04116.8 EIE81619.1 - 1.9e-12 47.5 8.4 1.9e-12 47.5 5.9 2.2 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily MBA1 PF07961.6 EIE81621.1 - 0.033 13.0 0.0 0.043 12.6 0.0 1.2 1 0 0 1 1 1 0 MBA1-like protein Ribonuc_red_sm PF00268.16 EIE81621.1 - 0.063 12.2 0.1 0.085 11.8 0.0 1.3 1 0 0 1 1 1 0 Ribonucleotide reductase, small chain YyzF PF14116.1 EIE81621.1 - 0.099 12.6 1.4 0.29 11.0 0.3 2.1 2 0 0 2 2 2 0 YyzF-like protein YWFCY PF14293.1 EIE81622.1 - 0.11 12.4 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 YWFCY protein PUF PF00806.14 EIE81624.1 - 2e-45 149.7 15.0 4.2e-07 29.0 0.1 7.3 7 0 0 7 7 7 6 Pumilio-family RNA binding repeat Takusan PF04822.8 EIE81624.1 - 0.15 11.8 2.5 0.19 11.5 0.1 2.5 2 0 0 2 2 2 0 Takusan ATP-synt_C PF00137.16 EIE81625.1 - 6.2e-10 38.8 15.7 4.4e-08 32.9 2.4 3.4 3 1 1 4 4 4 2 ATP synthase subunit C TCR_zetazeta PF11628.3 EIE81625.1 - 0.0067 15.8 0.2 0.017 14.5 0.1 1.7 1 0 0 1 1 1 1 T-cell surface glycoprotein CD3 zeta chain DUF4079 PF13301.1 EIE81625.1 - 0.22 11.4 5.5 0.067 13.2 1.4 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF4079) Glyoxalase PF00903.20 EIE81626.1 - 3.7e-20 72.1 0.3 1.8e-14 53.8 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 EIE81626.1 - 7.3e-12 45.2 0.0 4.8e-06 26.5 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EIE81626.1 - 1e-09 38.9 0.0 2.1e-05 25.0 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_5 PF14696.1 EIE81626.1 - 4.1e-09 36.4 0.1 8.1e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.1 EIE81626.1 - 3.8e-05 23.6 0.1 0.0011 18.9 0.0 2.7 3 1 0 3 3 3 1 Glyoxalase-like domain Ribosomal_L35Ae PF01247.13 EIE81627.1 - 3.9e-42 141.9 1.5 4.3e-42 141.7 1.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 EIE81627.1 - 0.0029 17.4 0.1 0.34 10.8 0.0 2.1 2 0 0 2 2 2 2 RimM N-terminal domain Pkinase PF00069.20 EIE81628.1 - 2.7e-60 203.7 0.0 3.1e-60 203.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE81628.1 - 6.1e-40 136.9 0.0 7.3e-40 136.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE81628.1 - 1.2e-05 24.3 0.0 3.6e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EIE81628.1 - 0.007 16.1 0.2 0.013 15.2 0.1 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EIE81628.1 - 0.0093 15.0 2.1 0.0093 15.0 1.5 1.6 1 1 1 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EIE81628.1 - 0.013 15.0 0.3 0.024 14.2 0.2 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.17 EIE81628.1 - 0.031 13.6 0.0 0.052 12.8 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Whi5 PF08528.6 EIE81629.1 - 0.00085 18.8 0.0 0.0016 17.9 0.0 1.5 1 0 0 1 1 1 1 Whi5 like UQ_con PF00179.21 EIE81631.1 - 4.4e-14 52.0 2.3 5e-07 29.2 0.3 2.1 1 1 1 2 2 2 2 Ubiquitin-conjugating enzyme Pkip-1 PF06878.6 EIE81631.1 - 0.08 12.8 0.0 0.095 12.5 0.0 1.1 1 0 0 1 1 1 0 Pkip-1 protein RWD PF05773.17 EIE81631.1 - 0.1 12.5 0.1 0.13 12.1 0.1 1.4 1 1 0 1 1 1 0 RWD domain ACR_tran PF00873.14 EIE81632.1 - 0.56 7.5 2.7 0.7 7.2 1.9 1.1 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family DUF218 PF02698.12 EIE81636.1 - 2.8e-05 23.6 0.0 4.9e-05 22.8 0.0 1.4 1 1 0 1 1 1 1 DUF218 domain Serinc PF03348.10 EIE81637.1 - 3.5e-154 513.6 8.3 4.2e-154 513.3 5.8 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) FA_desaturase PF00487.19 EIE81637.1 - 0.00065 19.2 8.6 0.0062 16.0 4.1 2.5 2 0 0 2 2 2 2 Fatty acid desaturase G-gamma PF00631.17 EIE81638.1 - 2.5e-17 62.3 0.0 3.2e-17 62.0 0.0 1.1 1 0 0 1 1 1 1 GGL domain DJ-1_PfpI PF01965.19 EIE81639.1 - 7.3e-30 103.3 0.6 9.1e-30 103.0 0.4 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 EIE81639.1 - 2.4e-14 52.9 0.0 2.9e-14 52.6 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase GATase PF00117.23 EIE81639.1 - 0.053 12.9 0.0 0.064 12.6 0.0 1.3 1 0 0 1 1 1 0 Glutamine amidotransferase class-I PCMT PF01135.14 EIE81640.1 - 1.3e-71 240.4 0.0 1.5e-71 240.2 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 EIE81640.1 - 2.4e-08 33.6 0.0 2.7e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIE81640.1 - 5.2e-08 33.4 0.0 7.9e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIE81640.1 - 3.6e-05 23.5 0.0 5.1e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EIE81640.1 - 3.8e-05 23.3 0.0 5e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EIE81640.1 - 0.00015 21.1 0.0 0.00022 20.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 EIE81640.1 - 0.00024 20.3 0.0 0.00032 19.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 EIE81640.1 - 0.00039 19.5 0.0 0.00049 19.2 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family RrnaAD PF00398.15 EIE81640.1 - 0.00065 18.8 0.0 0.00079 18.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_11 PF08241.7 EIE81640.1 - 0.0009 19.6 0.0 0.0015 18.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIE81640.1 - 0.001 19.0 0.0 0.0026 17.8 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_3 PF01596.12 EIE81640.1 - 0.0016 17.5 0.0 0.0021 17.1 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase CMAS PF02353.15 EIE81640.1 - 0.0027 16.8 0.0 0.0037 16.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.12 EIE81640.1 - 0.024 13.7 0.0 0.032 13.2 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Fibrillarin PF01269.12 EIE81640.1 - 0.03 13.2 0.0 0.062 12.2 0.0 1.4 2 0 0 2 2 2 0 Fibrillarin Methyltransf_25 PF13649.1 EIE81640.1 - 0.039 14.3 0.0 0.057 13.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain GCD14 PF08704.5 EIE81640.1 - 0.052 13.0 0.0 0.065 12.7 0.0 1.1 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Methyltransf_12 PF08242.7 EIE81640.1 - 0.12 12.9 0.0 0.17 12.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.4 EIE81640.1 - 0.13 11.6 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_9 PF08003.6 EIE81640.1 - 0.13 10.9 0.0 0.19 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) DUF2093 PF09866.4 EIE81644.1 - 0.008 15.3 1.0 3.2 7.0 0.1 2.4 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2093) TPR_MLP1_2 PF07926.7 EIE81645.1 - 0.0069 16.1 0.8 0.012 15.3 0.6 1.4 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein Pox_A_type_inc PF04508.7 EIE81645.1 - 0.27 11.1 0.1 0.27 11.1 0.1 2.7 3 1 0 3 3 3 0 Viral A-type inclusion protein repeat ADIP PF11559.3 EIE81645.1 - 1.9 8.3 8.4 5.7 6.8 0.2 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Mod_r PF07200.8 EIE81645.1 - 3.9 7.3 7.1 20 5.0 0.2 3.0 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein FlgN PF05130.7 EIE81645.1 - 5.1 7.3 9.6 4 7.6 0.4 2.2 2 0 0 2 2 2 0 FlgN protein YihI PF04220.7 EIE81647.1 - 0.032 13.5 5.6 0.79 9.0 3.6 2.6 1 1 1 2 2 2 0 Der GTPase activator (YihI) Terminase_4 PF05119.7 EIE81647.1 - 0.048 13.8 0.1 0.17 12.0 0.1 2.0 1 0 0 1 1 1 0 Phage terminase, small subunit 2-oxoacid_dh PF00198.18 EIE81648.1 - 6e-86 287.4 0.0 8.2e-86 287.0 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) E3_binding PF02817.12 EIE81648.1 - 1.6e-18 65.9 0.3 5.1e-18 64.4 0.2 1.9 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl PF00364.17 EIE81648.1 - 3.2e-18 65.1 1.8 5.2e-18 64.4 0.4 2.0 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 EIE81648.1 - 0.004 16.7 0.2 0.21 11.2 0.0 2.5 2 0 0 2 2 2 1 Biotin-lipoyl like DUF2611 PF11022.3 EIE81650.1 - 1.9e-24 85.5 0.1 2.1e-24 85.3 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2611) DUF3789 PF12664.2 EIE81651.1 - 0.081 12.2 0.7 0.16 11.2 0.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3789) DUF3808 PF10300.4 EIE81652.1 - 3.3e-25 88.5 1.9 5.6e-25 87.8 1.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TRAPPC-Trs85 PF12739.2 EIE81652.1 - 0.0035 16.0 0.2 0.0048 15.5 0.1 1.1 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TPR_12 PF13424.1 EIE81652.1 - 0.014 15.3 2.0 0.45 10.4 0.0 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 EIE81652.1 - 0.014 15.2 5.1 27 4.9 0.2 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 EIE81652.1 - 0.068 12.8 1.4 2.9 7.6 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 EIE81652.1 - 0.13 12.7 0.6 19 5.9 0.2 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3808 PF10300.4 EIE81653.1 - 2.8e-14 52.5 0.0 2.8e-14 52.5 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3808) SAB PF04382.8 EIE81653.1 - 0.31 10.7 8.5 0.39 10.4 0.1 3.5 3 0 0 3 3 3 0 SAB domain BUD22 PF09073.5 EIE81653.1 - 1.9 7.4 38.3 4.9 6.1 26.5 1.7 1 0 0 1 1 1 0 BUD22 VIT1 PF01988.14 EIE81653.1 - 5.8 6.3 6.0 1.3 8.5 0.1 2.4 2 0 0 2 2 2 0 VIT family Pyr_redox_2 PF07992.9 EIE81654.1 - 1.4e-12 47.8 0.0 2.8e-12 46.9 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EIE81654.1 - 3.6e-10 40.1 0.3 3.1e-08 33.9 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EIE81654.1 - 7.5e-06 26.1 2.1 0.34 10.9 0.0 3.3 1 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EIE81654.1 - 0.00018 20.5 1.0 1.5 7.6 0.0 3.2 2 1 1 3 3 3 2 Lycopene cyclase protein NAD_binding_9 PF13454.1 EIE81654.1 - 0.00022 21.0 1.2 20 4.9 0.0 4.5 3 2 1 5 5 5 0 FAD-NAD(P)-binding HI0933_like PF03486.9 EIE81654.1 - 0.0041 15.6 1.0 0.55 8.6 0.1 2.5 2 0 0 2 2 2 2 HI0933-like protein K_oxygenase PF13434.1 EIE81654.1 - 0.013 14.4 0.0 0.082 11.8 0.0 2.0 1 1 1 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.9 EIE81654.1 - 0.097 11.2 3.0 5.3 5.5 0.1 3.0 3 1 0 3 3 3 0 Tryptophan halogenase GIDA PF01134.17 EIE81654.1 - 0.12 11.2 0.1 16 4.1 0.0 3.3 4 0 0 4 4 4 0 Glucose inhibited division protein A NAD_binding_7 PF13241.1 EIE81654.1 - 0.16 12.2 2.6 0.15 12.3 0.2 2.1 2 1 0 2 2 2 0 Putative NAD(P)-binding DAO PF01266.19 EIE81654.1 - 0.16 10.8 2.8 44 2.8 0.0 3.5 3 1 1 4 4 4 0 FAD dependent oxidoreductase START PF01852.14 EIE81655.1 - 2.3e-05 23.8 0.1 0.0085 15.4 0.0 2.2 1 1 1 2 2 2 2 START domain Shikimate_DH PF01488.15 EIE81655.1 - 0.064 13.3 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Ribosomal_L18p PF00861.17 EIE81656.1 - 4.5e-44 149.4 0.0 9.3e-44 148.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 EIE81656.1 - 2.5e-30 104.8 2.8 2.5e-30 104.8 2.0 1.7 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region NDK PF00334.14 EIE81657.1 - 5.1e-19 68.4 1.0 2.1e-18 66.4 0.0 2.6 2 1 1 3 3 3 1 Nucleoside diphosphate kinase HSCB_C PF07743.8 EIE81658.1 - 3.5e-15 56.2 8.4 3.8e-15 56.0 5.8 1.0 1 0 0 1 1 1 1 HSCB C-terminal oligomerisation domain DUF4570 PF15134.1 EIE81658.1 - 0.016 15.0 1.1 0.017 14.9 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) Gag_p24 PF00607.15 EIE81658.1 - 0.039 13.4 0.3 0.039 13.4 0.2 1.1 1 0 0 1 1 1 0 gag gene protein p24 (core nucleocapsid protein) ACCA PF03255.9 EIE81658.1 - 0.047 13.2 0.9 0.051 13.1 0.6 1.1 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF288 PF03385.12 EIE81658.1 - 0.072 11.5 0.1 0.069 11.6 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function, DUF288 Arc PF03869.9 EIE81658.1 - 0.28 10.8 1.1 8.1 6.1 0.8 2.2 1 1 0 1 1 1 0 Arc-like DNA binding domain cwf21 PF08312.7 EIE81658.1 - 0.55 10.1 7.0 0.74 9.7 4.9 1.4 1 1 0 1 1 1 0 cwf21 domain MFS_1 PF07690.11 EIE81659.1 - 5.6e-27 94.3 3.4 6.9e-27 94.0 2.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 EIE81659.1 - 0.00045 18.7 0.6 0.0021 16.5 0.0 1.8 2 0 0 2 2 2 1 MFS/sugar transport protein Sugar_tr PF00083.19 EIE81659.1 - 0.0012 17.5 2.3 0.018 13.6 0.0 2.8 2 1 0 2 2 2 1 Sugar (and other) transporter TauE PF01925.14 EIE81659.1 - 0.016 14.6 8.6 0.089 12.2 0.5 2.7 2 1 1 3 3 3 0 Sulfite exporter TauE/SafE tRNA-synt_2c PF01411.14 EIE81660.1 - 7e-156 519.7 0.0 5.1e-149 497.0 0.0 2.1 1 1 1 2 2 2 2 tRNA synthetases class II (A) tRNA_SAD PF07973.9 EIE81660.1 - 3.7e-13 49.1 0.1 1.2e-12 47.4 0.1 2.0 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 EIE81660.1 - 0.005 16.5 0.1 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 DHHA1 domain DUF2188 PF09954.4 EIE81660.1 - 0.06 13.2 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2188) zf-C2H2_4 PF13894.1 EIE81661.1 - 3e-06 27.1 8.6 0.0047 17.1 0.3 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EIE81661.1 - 8.2e-06 25.8 9.9 2e-05 24.6 1.1 3.7 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 EIE81661.1 - 3.5e-05 23.8 14.4 0.0011 19.1 0.6 3.5 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EIE81661.1 - 0.3 11.0 4.6 0.11 12.4 0.8 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger DUF3505 PF12013.3 EIE81661.1 - 0.53 10.5 6.9 4 7.7 0.1 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF3505) zf-TRAF PF02176.13 EIE81661.1 - 6.3 7.2 6.2 0.65 10.4 0.8 2.0 2 0 0 2 2 2 0 TRAF-type zinc finger zf-RING_2 PF13639.1 EIE81665.1 - 2.8e-09 36.6 11.7 4.4e-09 36.0 8.1 1.3 1 0 0 1 1 1 1 Ring finger domain FHA PF00498.21 EIE81665.1 - 1.9e-05 24.7 0.1 7.4e-05 22.7 0.1 2.0 1 1 0 1 1 1 1 FHA domain zf-rbx1 PF12678.2 EIE81665.1 - 0.00044 20.3 6.0 0.00092 19.2 4.1 1.5 1 1 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EIE81665.1 - 0.0029 17.4 2.6 0.0048 16.6 1.8 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 EIE81665.1 - 0.0034 17.0 9.8 0.0063 16.2 6.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EIE81665.1 - 0.0052 16.4 8.5 0.01 15.5 5.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIE81665.1 - 0.0058 16.2 10.6 0.01 15.4 7.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIE81665.1 - 0.014 15.4 12.7 0.025 14.6 8.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.7 EIE81665.1 - 0.084 12.0 0.2 0.12 11.6 0.1 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger PHD PF00628.24 EIE81665.1 - 0.31 10.7 6.7 0.55 9.9 4.7 1.4 1 0 0 1 1 1 0 PHD-finger NDT80_PhoG PF05224.7 EIE81666.1 - 1.3e-39 136.1 0.2 4.6e-39 134.3 0.2 2.0 1 1 0 1 1 1 1 NDT80 / PhoG like DNA-binding family SWIRM PF04433.12 EIE81667.1 - 8.7e-19 67.4 0.2 3.4e-18 65.5 0.1 2.1 2 0 0 2 2 2 1 SWIRM domain JAB PF01398.16 EIE81667.1 - 1.4e-13 50.5 0.0 4e-13 49.1 0.0 1.8 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 EIE81667.1 - 5.5e-08 32.3 0.0 1.4e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Myb_DNA-binding PF00249.26 EIE81667.1 - 0.0092 16.0 0.0 0.025 14.6 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EIE81667.1 - 0.067 13.3 0.1 0.25 11.4 0.0 2.0 1 0 0 1 1 1 0 Myb-like DNA-binding domain HTH_28 PF13518.1 EIE81668.1 - 0.031 14.2 0.0 0.054 13.5 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain SBDS_C PF09377.5 EIE81670.1 - 0.084 12.5 0.0 0.19 11.4 0.0 1.6 1 1 0 1 1 1 0 SBDS protein C-terminal domain eIF2A PF08662.6 EIE81671.1 - 0.011 15.4 0.0 0.04 13.6 0.0 1.7 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A FliC PF12445.3 EIE81673.1 - 9.2 6.4 7.0 44 4.1 5.0 1.9 1 1 1 2 2 2 0 Flagellin protein bZIP_1 PF00170.16 EIE81674.1 - 1.3e-11 44.2 3.5 2.2e-11 43.5 2.5 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EIE81674.1 - 1.3e-09 37.7 5.5 2.4e-09 36.8 3.8 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EIE81674.1 - 0.0017 18.6 7.2 0.0029 17.8 4.8 1.6 1 1 0 1 1 1 1 bZIP Maf transcription factor bZIP_1 PF00170.16 EIE81675.1 - 6.2e-08 32.4 14.4 4.9e-07 29.6 9.9 2.1 1 1 0 1 1 1 1 bZIP transcription factor DegS PF05384.6 EIE81675.1 - 0.0012 18.0 5.1 0.0021 17.3 3.6 1.3 1 0 0 1 1 1 1 Sensor protein DegS FlaC_arch PF05377.6 EIE81675.1 - 0.0066 16.3 3.6 0.0092 15.8 1.8 1.8 2 0 0 2 2 1 1 Flagella accessory protein C (FlaC) Golgin_A5 PF09787.4 EIE81675.1 - 0.015 13.8 6.3 0.019 13.5 4.4 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 bZIP_2 PF07716.10 EIE81675.1 - 0.015 15.0 20.8 0.19 11.5 4.9 2.5 1 1 1 2 2 2 0 Basic region leucine zipper IncA PF04156.9 EIE81675.1 - 0.019 14.6 7.3 0.026 14.1 5.0 1.2 1 0 0 1 1 1 0 IncA protein KLRAQ PF10205.4 EIE81675.1 - 0.021 14.8 8.8 0.033 14.1 6.1 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein Adeno_PIX PF03955.9 EIE81675.1 - 0.033 14.7 1.2 0.067 13.7 0.8 1.5 1 0 0 1 1 1 0 Adenovirus hexon-associated protein (IX) Herpes_UL6 PF01763.11 EIE81675.1 - 0.034 12.3 2.7 0.04 12.0 1.9 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like Spc24 PF08286.6 EIE81675.1 - 0.043 13.5 4.6 0.083 12.5 3.2 1.5 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 TMF_TATA_bd PF12325.3 EIE81675.1 - 0.061 13.0 6.5 0.091 12.4 4.5 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Atg14 PF10186.4 EIE81675.1 - 0.066 12.1 8.2 0.089 11.7 5.7 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF972 PF06156.8 EIE81675.1 - 0.09 13.1 4.2 0.14 12.5 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF2730 PF10805.3 EIE81675.1 - 0.11 12.2 1.3 0.19 11.4 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) bZIP_Maf PF03131.12 EIE81675.1 - 0.14 12.4 13.1 0.32 11.3 9.1 1.6 1 1 0 1 1 1 0 bZIP Maf transcription factor Reo_sigmaC PF04582.7 EIE81675.1 - 0.15 11.1 0.2 0.19 10.9 0.1 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein TetR_C_4 PF08359.6 EIE81675.1 - 0.16 11.8 1.0 0.26 11.2 0.7 1.3 1 0 0 1 1 1 0 YsiA-like protein, C-terminal region DUF465 PF04325.8 EIE81675.1 - 0.17 11.6 3.1 0.32 10.7 2.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF465) GAS PF13851.1 EIE81675.1 - 0.17 11.0 9.1 0.25 10.4 6.3 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding V_ATPase_I PF01496.14 EIE81675.1 - 0.24 9.2 4.4 0.29 8.9 3.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6 PF04111.7 EIE81675.1 - 0.24 10.3 7.0 0.31 10.0 4.9 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DivIC PF04977.10 EIE81675.1 - 0.26 10.7 8.4 0.32 10.5 5.0 1.8 1 1 0 1 1 1 0 Septum formation initiator CENP-H PF05837.7 EIE81675.1 - 0.31 11.2 7.0 0.36 11.0 4.4 1.5 1 1 0 1 1 1 0 Centromere protein H (CENP-H) Phage_GP20 PF06810.6 EIE81675.1 - 0.4 10.0 7.6 0.4 10.1 4.6 1.5 1 1 0 1 1 1 0 Phage minor structural protein GP20 SPT16 PF08644.6 EIE81675.1 - 0.46 10.3 3.4 0.73 9.6 2.3 1.3 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) HAUS6_N PF14661.1 EIE81675.1 - 0.49 9.7 6.1 0.63 9.3 4.3 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus NYD-SP28_assoc PF14775.1 EIE81675.1 - 0.72 9.5 5.2 1.4 8.6 3.6 1.5 1 0 0 1 1 1 0 Sperm tail C-terminal domain PspB PF06667.7 EIE81675.1 - 1.5 8.8 3.5 3.3 7.6 2.4 1.7 1 1 0 1 1 1 0 Phage shock protein B Mnd1 PF03962.10 EIE81675.1 - 2.5 7.7 8.4 5.2 6.6 5.8 1.5 1 1 0 1 1 1 0 Mnd1 family DUF4407 PF14362.1 EIE81675.1 - 7.7 5.3 7.7 10 4.9 5.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GalKase_gal_bdg PF10509.4 EIE81676.1 - 1.6e-22 78.5 0.1 3.2e-22 77.5 0.1 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.21 EIE81676.1 - 8.4e-15 54.5 3.5 4.9e-14 52.1 1.9 2.5 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EIE81676.1 - 1.1e-14 54.3 0.0 2.6e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal Sigma70_r4 PF04545.11 EIE81676.1 - 0.00013 21.2 0.1 0.0014 17.9 0.0 2.3 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_23 PF13384.1 EIE81676.1 - 0.0095 15.5 0.0 0.02 14.5 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain RPEL PF02755.10 EIE81677.1 - 8.6e-24 82.1 18.5 2.6e-08 32.9 0.2 4.3 4 0 0 4 4 4 4 RPEL repeat DnaI_N PF07319.6 EIE81677.1 - 0.043 14.0 0.7 0.13 12.5 0.1 2.0 1 1 1 2 2 2 0 Primosomal protein DnaI N-terminus Sigma70_r3 PF04539.11 EIE81677.1 - 0.73 9.7 4.0 0.58 10.0 0.1 2.6 2 1 0 3 3 3 0 Sigma-70 region 3 Ribosomal_S21 PF01165.15 EIE81678.1 - 6.1e-12 44.8 2.6 1.1e-11 43.9 1.3 1.8 2 0 0 2 2 2 1 Ribosomal protein S21 Exostosin PF03016.10 EIE81679.1 - 9.7e-41 139.7 0.3 1.4e-40 139.2 0.2 1.2 1 0 0 1 1 1 1 Exostosin family Amidohydro_4 PF13147.1 EIE81679.1 - 4.6e-23 82.6 0.1 1.6e-22 80.8 0.1 1.8 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EIE81679.1 - 1e-20 74.6 0.0 6.6e-20 72.0 0.0 2.0 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 EIE81679.1 - 1.8e-05 24.1 0.4 0.00094 18.4 0.0 2.8 2 1 1 3 3 3 1 Amidohydrolase family Amidohydro_5 PF13594.1 EIE81679.1 - 0.00017 21.3 0.2 0.0005 19.8 0.1 1.9 1 0 0 1 1 1 1 Amidohydrolase Ribosomal_L16 PF00252.13 EIE81680.1 - 1e-33 115.8 0.1 1.3e-33 115.6 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e GHL13 PF14883.1 EIE81682.1 - 0.039 13.0 4.3 0.056 12.5 0.0 2.5 3 0 0 3 3 3 0 Hypothetical glycosyl hydrolase family 13 SRP54_N PF02881.14 EIE81682.1 - 0.16 12.0 2.3 1 9.5 0.0 3.4 5 0 0 5 5 5 0 SRP54-type protein, helical bundle domain Hydantoinase_B PF02538.9 EIE81682.1 - 0.2 9.8 1.1 0.27 9.4 0.7 1.1 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase FUSC PF04632.7 EIE81682.1 - 4.8 5.4 6.6 6.3 5.0 4.5 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family PIP49_C PF12260.3 EIE81683.1 - 0.12 11.8 2.9 0.15 11.4 2.0 1.2 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 CFEM PF05730.6 EIE81683.1 - 1.7 8.5 9.5 4.7 7.0 6.5 1.9 1 1 0 1 1 1 0 CFEM domain Ribosomal_L15e PF00827.12 EIE81685.1 - 7.4e-90 299.6 12.3 8.5e-90 299.4 8.5 1.0 1 0 0 1 1 1 1 Ribosomal L15 STE2 PF02116.10 EIE81687.1 - 0.0091 15.0 0.6 0.01 14.8 0.4 1.0 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR LRR_8 PF13855.1 EIE81688.1 - 1.3e-07 31.2 1.8 0.0056 16.4 0.3 3.5 1 1 3 4 4 4 3 Leucine rich repeat LRR_6 PF13516.1 EIE81688.1 - 7.9e-07 28.5 3.4 0.32 11.1 0.0 5.7 5 1 1 6 6 6 2 Leucine Rich repeat LRR_1 PF00560.28 EIE81688.1 - 2.2e-06 26.8 1.1 1.4 9.2 0.2 5.1 4 2 0 4 4 4 2 Leucine Rich Repeat LRR_4 PF12799.2 EIE81688.1 - 2.5e-06 26.9 0.0 0.31 10.7 0.0 4.4 2 2 3 5 5 5 3 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EIE81688.1 - 5.6e-05 22.7 4.3 24 5.7 0.0 6.3 6 1 1 7 7 7 1 Leucine rich repeat Chromate_transp PF02417.10 EIE81689.1 - 0.01 15.4 1.7 0.016 14.7 1.2 1.2 1 0 0 1 1 1 0 Chromate transporter FtsX PF02687.16 EIE81689.1 - 0.015 15.0 0.9 0.22 11.2 1.1 1.9 2 0 0 2 2 2 0 FtsX-like permease family Acyl_transf_3 PF01757.17 EIE81689.1 - 0.037 12.8 0.3 0.053 12.3 0.2 1.2 1 0 0 1 1 1 0 Acyltransferase family DUF588 PF04535.7 EIE81689.1 - 0.068 12.7 0.5 0.13 11.8 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF588) DctQ PF04290.7 EIE81689.1 - 0.073 12.8 1.4 2.4 7.9 0.9 2.1 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component DUF2975 PF11188.3 EIE81689.1 - 0.11 12.1 4.4 0.54 9.9 1.4 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF2975) DUF3995 PF13160.1 EIE81689.1 - 0.25 11.4 2.5 0.45 10.5 0.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3995) DUF4149 PF13664.1 EIE81689.1 - 0.26 11.3 2.4 0.31 11.1 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) DUF4131 PF13567.1 EIE81689.1 - 0.29 10.5 3.1 0.21 11.0 0.5 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) DUF4233 PF14017.1 EIE81689.1 - 0.34 10.8 2.4 0.95 9.4 1.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4233) MARVEL PF01284.18 EIE81689.1 - 0.74 9.6 4.2 2.8 7.7 3.1 1.7 1 1 0 1 1 1 0 Membrane-associating domain Claudin_2 PF13903.1 EIE81689.1 - 2 8.0 5.4 16 5.1 4.3 1.8 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction KilA-N PF04383.8 EIE81690.1 - 0.00059 19.4 0.0 0.002 17.7 0.0 1.9 1 1 0 1 1 1 1 KilA-N domain Arb2 PF09757.4 EIE81691.1 - 4e-18 65.4 0.0 6.7e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 Arb2 domain CsbD PF05532.7 EIE81692.1 - 0.00059 19.4 0.0 0.16 11.6 0.0 2.3 2 0 0 2 2 2 2 CsbD-like THOC7 PF05615.8 EIE81692.1 - 0.094 12.9 0.1 0.094 12.9 0.1 1.4 2 0 0 2 2 2 0 Tho complex subunit 7 Ribosomal_L4 PF00573.17 EIE81693.1 - 8.3e-45 152.5 0.9 8.3e-45 152.5 0.6 1.5 2 0 0 2 2 2 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 EIE81693.1 - 1.3e-29 101.9 2.5 1.3e-29 101.9 1.7 2.3 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain C2 PF00168.25 EIE81694.1 - 6.1e-51 170.2 4.4 1e-18 66.9 0.0 6.1 5 1 1 6 6 6 4 C2 domain WD40 PF00400.27 EIE81695.1 - 8.1e-56 184.0 18.8 2.7e-09 36.5 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EIE81695.1 - 0.00042 20.0 0.0 0.66 9.6 0.0 2.6 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EIE81695.1 - 0.043 11.9 0.3 3.6 5.6 0.0 2.4 3 0 0 3 3 3 0 Nucleoporin Nup120/160 DUF4449 PF14613.1 EIE81696.1 - 5e-09 36.2 1.8 5e-09 36.2 1.2 3.1 3 1 0 3 3 3 1 Protein of unknown function (DUF4449) PRD PF00874.15 EIE81696.1 - 0.0055 16.7 0.2 0.036 14.1 0.0 2.4 2 0 0 2 2 2 1 PRD domain DUF1374 PF07118.6 EIE81696.1 - 0.043 13.9 2.1 0.11 12.5 1.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1374) DSHCT PF08148.7 EIE81696.1 - 0.12 11.6 3.5 0.18 11.0 0.2 2.8 3 1 0 3 3 3 0 DSHCT (NUC185) domain Oxidored_FMN PF00724.15 EIE81697.1 - 2.6e-66 223.9 0.0 3.7e-66 223.4 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Fasciclin PF02469.17 EIE81697.1 - 1.5e-22 79.9 14.9 1.5e-14 54.1 2.4 4.5 5 0 0 5 5 5 4 Fasciclin domain SET_assoc PF11767.3 EIE81697.1 - 0.13 11.5 0.0 0.29 10.4 0.0 1.6 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated PEX11 PF05648.9 EIE81698.1 - 1.4e-18 66.9 1.4 2.7e-18 66.0 1.0 1.4 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) phiKZ_IP PF12699.2 EIE81698.1 - 0.13 11.1 1.6 1.2 7.9 0.0 2.1 2 0 0 2 2 2 0 phiKZ-like phage internal head proteins Sigma54_DBD PF04552.8 EIE81701.1 - 0.05 13.1 0.1 0.25 10.8 0.0 1.9 1 1 1 2 2 2 0 Sigma-54, DNA binding domain HTH_38 PF13936.1 EIE81701.1 - 0.073 12.6 0.1 0.16 11.5 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain ETS_PEA3_N PF04621.8 EIE81702.1 - 0.14 11.3 0.9 0.18 11.0 0.6 1.1 1 0 0 1 1 1 0 PEA3 subfamily ETS-domain transcription factor N terminal domain rve PF00665.21 EIE81704.1 - 6.1e-28 97.3 0.0 1.2e-27 96.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 EIE81704.1 - 1.6e-05 24.3 0.0 4.1e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.5 EIE81704.1 - 0.0014 17.9 0.4 0.0033 16.7 0.3 1.6 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger RVT_1 PF00078.22 EIE81705.1 - 3e-27 95.3 0.2 5.8e-27 94.4 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_Tnp_IS1595 PF12762.2 EIE81706.1 - 3.1e-18 66.0 2.1 2.2e-12 47.0 0.1 3.1 2 1 0 2 2 2 2 ISXO2-like transposase domain Retrotrans_gag PF03732.12 EIE81707.1 - 0.0075 16.3 0.0 0.0075 16.3 0.0 3.1 2 1 0 2 2 2 1 Retrotransposon gag protein HTH_Tnp_Tc3_2 PF01498.13 EIE81708.1 - 4.5e-10 39.4 1.2 6e-10 39.0 0.9 1.1 1 0 0 1 1 1 1 Transposase HALZ PF02183.13 EIE81709.1 - 0.00067 19.3 1.0 0.0015 18.1 0.4 1.8 1 1 0 1 1 1 1 Homeobox associated leucine zipper TPR_MLP1_2 PF07926.7 EIE81709.1 - 0.00068 19.3 0.7 0.001 18.8 0.5 1.2 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.7 EIE81709.1 - 0.0055 15.9 4.5 0.0079 15.4 3.1 1.2 1 0 0 1 1 1 1 Reovirus sigma C capsid protein CCDC155 PF14662.1 EIE81709.1 - 0.0064 16.1 1.2 0.0096 15.5 0.8 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 ADIP PF11559.3 EIE81709.1 - 0.008 16.0 2.3 0.016 15.1 1.6 1.5 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding DUF904 PF06005.7 EIE81709.1 - 0.011 16.0 2.5 0.022 15.0 1.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DUF972 PF06156.8 EIE81709.1 - 0.02 15.2 0.3 0.038 14.3 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) GAS PF13851.1 EIE81709.1 - 0.038 13.1 1.0 0.058 12.5 0.7 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Phage_GP20 PF06810.6 EIE81709.1 - 0.044 13.2 0.7 0.074 12.4 0.5 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 DivIC PF04977.10 EIE81709.1 - 0.052 13.0 1.3 0.1 12.0 0.5 1.7 1 1 0 1 1 1 0 Septum formation initiator Baculo_PEP_C PF04513.7 EIE81709.1 - 0.081 12.7 7.6 0.15 11.9 5.3 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF869 PF05911.6 EIE81709.1 - 0.083 11.1 2.8 0.13 10.5 1.9 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) DivIVA PF05103.8 EIE81709.1 - 0.11 12.5 1.5 0.22 11.6 0.1 2.0 1 1 1 2 2 2 0 DivIVA protein DUF2205 PF10224.4 EIE81709.1 - 0.22 11.1 1.8 0.37 10.4 1.2 1.3 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) bZIP_2 PF07716.10 EIE81709.1 - 0.22 11.3 3.3 3.7 7.4 0.1 2.5 1 1 1 2 2 2 0 Basic region leucine zipper DUF342 PF03961.8 EIE81709.1 - 0.22 9.8 0.3 0.31 9.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Exo_endo_phos_2 PF14529.1 EIE81710.1 - 8.2e-14 51.2 0.0 1.1e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EIE81710.1 - 0.029 14.3 0.1 0.042 13.7 0.1 1.2 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family rve PF00665.21 EIE81711.1 - 1.9e-22 79.6 0.0 4.7e-22 78.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE81711.1 - 1.5e-15 57.1 0.1 2.9e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.12 EIE81711.1 - 8.5e-09 35.3 0.1 2.4e-08 33.9 0.1 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein Chromo PF00385.19 EIE81711.1 - 4.4e-08 32.6 0.1 1e-07 31.5 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.1 EIE81711.1 - 5.3e-05 23.6 0.0 0.00012 22.4 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.5 EIE81711.1 - 0.00044 19.5 1.6 0.0015 17.8 1.1 2.0 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Asp_protease PF09668.5 EIE81711.1 - 0.0082 15.7 0.0 0.019 14.5 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EIE81711.1 - 0.023 14.4 0.0 0.058 13.2 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease UBN2 PF14223.1 EIE81711.1 - 0.14 11.9 0.0 0.37 10.5 0.0 1.8 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type HTH_Tnp_Tc3_2 PF01498.13 EIE81712.1 - 6.1e-09 35.8 0.5 8.4e-09 35.3 0.3 1.2 1 0 0 1 1 1 1 Transposase Atg8 PF02991.11 EIE81712.1 - 0.12 12.3 0.1 0.18 11.8 0.1 1.3 1 0 0 1 1 1 0 Autophagy protein Atg8 ubiquitin like DDE_3 PF13358.1 EIE81713.1 - 1.9e-08 34.1 0.0 5.8e-08 32.5 0.0 1.8 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_28 PF13518.1 EIE81713.1 - 0.00049 20.0 1.1 0.0097 15.8 0.0 3.2 4 0 0 4 4 4 1 Helix-turn-helix domain HTH_23 PF13384.1 EIE81713.1 - 0.0058 16.2 0.0 0.021 14.4 0.0 2.0 2 0 0 2 2 2 1 Homeodomain-like domain HTH_psq PF05225.11 EIE81713.1 - 0.041 13.4 0.0 0.31 10.6 0.0 2.2 2 0 0 2 2 2 0 helix-turn-helix, Psq domain Imm40 PF15582.1 EIE81717.1 - 0.035 12.8 0.1 0.043 12.5 0.1 1.1 1 0 0 1 1 1 0 Immunity protein 40 SRR PF07709.6 EIE81717.1 - 1.4 9.4 3.7 54 4.6 0.0 3.3 3 0 0 3 3 3 0 Seven Residue Repeat DDE_3 PF13358.1 EIE81718.1 - 4.7e-21 75.0 0.0 9.9e-21 74.0 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE81718.1 - 5.8e-15 55.1 1.7 1.8e-14 53.5 0.3 2.4 3 0 0 3 3 3 1 Transposase HTH_38 PF13936.1 EIE81718.1 - 1.6e-05 24.3 0.0 3.6e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.1 EIE81718.1 - 0.00042 19.8 0.0 0.0031 17.1 0.0 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.1 EIE81718.1 - 0.00083 19.4 0.3 0.014 15.5 0.2 2.7 2 1 0 2 2 1 1 Winged helix-turn helix HTH_28 PF13518.1 EIE81718.1 - 0.0018 18.2 0.0 0.0062 16.5 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.7 EIE81718.1 - 0.0035 16.7 0.5 0.027 13.9 0.0 2.6 3 0 0 3 3 3 1 Sigma-70, region 4 rve PF00665.21 EIE81718.1 - 0.0038 17.3 0.0 0.01 15.9 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain HTH_7 PF02796.10 EIE81718.1 - 0.0078 16.0 0.4 0.11 12.3 0.0 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_Tnp_4 PF13613.1 EIE81718.1 - 0.027 14.0 0.1 0.062 12.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_21 PF13276.1 EIE81718.1 - 0.034 14.1 0.1 3 7.9 0.0 2.9 3 0 0 3 3 3 0 HTH-like domain CPSase_L_D3 PF02787.14 EIE81718.1 - 0.053 13.2 0.1 0.16 11.7 0.0 1.8 2 0 0 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain HTH_32 PF13565.1 EIE81718.1 - 0.1 13.4 3.6 17 6.2 0.1 4.1 3 1 1 4 4 3 0 Homeodomain-like domain LacI PF00356.16 EIE81718.1 - 0.62 9.7 3.5 15 5.2 0.0 2.9 4 0 0 4 4 4 0 Bacterial regulatory proteins, lacI family rve PF00665.21 EIE81720.1 - 1.9e-24 86.0 0.0 5.6e-24 84.5 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE81720.1 - 6.6e-17 61.5 0.0 1.3e-16 60.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE81720.1 - 9.1e-11 41.2 0.6 2.6e-10 39.8 0.4 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 EIE81720.1 - 0.00036 19.8 0.1 0.001 18.4 0.1 1.9 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger UBN2_2 PF14227.1 EIE81720.1 - 0.018 14.6 1.1 0.33 10.5 0.0 2.8 3 0 0 3 3 3 0 gag-polypeptide of LTR copia-type rve_3 PF13683.1 EIE81720.1 - 0.027 14.0 0.0 0.087 12.3 0.0 1.9 1 0 0 1 1 1 0 Integrase core domain UBN2 PF14223.1 EIE81720.1 - 0.063 13.0 0.6 0.16 11.7 0.1 1.9 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type HTH_23 PF13384.1 EIE81721.1 - 3.4e-06 26.5 0.0 3.6e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Homeodomain-like domain HTH_7 PF02796.10 EIE81721.1 - 0.00039 20.2 0.1 0.00064 19.5 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase GcrA PF07750.6 EIE81721.1 - 0.017 15.2 0.0 0.017 15.2 0.0 1.1 1 0 0 1 1 1 0 GcrA cell cycle regulator DUF433 PF04255.9 EIE81721.1 - 0.021 14.2 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF433) HTH_28 PF13518.1 EIE81721.1 - 0.036 14.0 0.0 0.091 12.7 0.0 1.7 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_38 PF13936.1 EIE81721.1 - 0.094 12.2 0.1 0.21 11.1 0.1 1.6 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.1 EIE81721.1 - 0.11 12.6 0.0 0.12 12.5 0.0 1.1 1 0 0 1 1 1 0 Winged helix-turn helix HTH_24 PF13412.1 EIE81721.1 - 0.11 11.8 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding rve PF00665.21 EIE81722.1 - 3.5e-17 62.6 0.0 7.6e-17 61.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE81722.1 - 5.1e-17 61.9 0.2 1.2e-16 60.7 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE81722.1 - 4.4e-09 35.8 0.5 1.1e-08 34.6 0.3 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.1 EIE81722.1 - 3.2e-07 30.7 0.1 8e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 EIE81722.1 - 1.4e-06 28.1 0.1 1.2e-05 25.1 0.0 2.7 2 0 0 2 2 2 1 Retroviral aspartyl protease Retrotrans_gag PF03732.12 EIE81722.1 - 0.00038 20.4 0.1 0.005 16.8 0.0 3.0 3 0 0 3 3 3 1 Retrotransposon gag protein gag-asp_proteas PF13975.1 EIE81722.1 - 0.00052 19.7 0.0 0.0012 18.6 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.5 EIE81722.1 - 0.025 14.1 1.1 0.12 11.9 0.1 2.4 3 0 0 3 3 3 0 Aspartyl protease Tudor-knot PF11717.3 EIE81722.1 - 0.058 13.1 2.9 0.079 12.6 0.1 2.6 2 0 0 2 2 2 0 RNA binding activity-knot of a chromodomain PMC2NT PF08066.7 EIE81722.1 - 0.13 12.5 3.0 11 6.4 0.0 3.3 3 0 0 3 3 3 0 PMC2NT (NUC016) domain rve PF00665.21 EIE81723.1 - 3.1e-17 62.8 0.0 6.7e-17 61.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE81723.1 - 4.3e-17 62.1 0.2 1e-16 60.9 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE81723.1 - 4.1e-09 35.9 0.5 9.5e-09 34.8 0.3 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.1 EIE81723.1 - 2.8e-07 30.9 0.1 7.1e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 EIE81723.1 - 1.3e-06 28.2 0.1 1.1e-05 25.2 0.0 2.6 2 0 0 2 2 2 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EIE81723.1 - 0.00048 19.9 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.12 EIE81723.1 - 0.0012 18.8 0.2 0.013 15.5 0.0 2.9 3 0 0 3 3 3 1 Retrotransposon gag protein Tudor-knot PF11717.3 EIE81723.1 - 0.02 14.5 0.1 0.07 12.8 0.1 1.9 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain Asp_protease PF09668.5 EIE81723.1 - 0.024 14.2 1.3 0.11 12.0 0.1 2.5 3 0 0 3 3 3 0 Aspartyl protease Peptidase_M3_N PF08439.5 EIE81723.1 - 0.11 12.5 1.7 0.19 11.7 0.2 2.2 2 0 0 2 2 2 0 Oligopeptidase F DUF4498 PF14926.1 EIE81724.1 - 0.013 14.6 0.2 0.013 14.6 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4498) Transposase_21 PF02992.9 EIE81725.1 - 6.6e-23 80.9 0.1 6.6e-23 80.9 0.1 1.6 2 0 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.1 EIE81725.1 - 0.0002 20.7 0.3 0.00043 19.7 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) DUF2847 PF11009.3 EIE81727.1 - 0.069 12.7 0.1 0.069 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) HTH_Tnp_Tc3_2 PF01498.13 EIE81728.1 - 2e-09 37.3 0.6 5e-09 36.0 0.5 1.6 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.1 EIE81728.1 - 0.02 14.6 0.0 0.037 13.7 0.0 1.5 1 0 0 1 1 1 0 DDE superfamily endonuclease DDE_3 PF13358.1 EIE81729.1 - 2.5e-17 63.0 0.0 6.6e-17 61.6 0.0 1.8 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE81729.1 - 8.2e-09 35.4 1.1 2e-08 34.1 0.7 1.8 1 1 0 1 1 1 1 Transposase HTH_Tnp_Tc3_2 PF01498.13 EIE81730.1 - 3.5e-08 33.3 0.3 3.5e-08 33.3 0.2 2.1 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 EIE81730.1 - 0.00034 20.7 1.9 0.00073 19.6 1.3 1.6 1 1 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_ISL3 PF13542.1 EIE81730.1 - 0.0059 15.7 1.8 0.02 14.0 0.5 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_32 PF13565.1 EIE81730.1 - 0.054 14.2 2.8 0.066 14.0 0.9 2.0 2 0 0 2 2 2 0 Homeodomain-like domain HTH_12 PF08461.5 EIE81730.1 - 0.062 13.0 0.1 0.19 11.4 0.1 1.8 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain DUF4330 PF14221.1 EIE81730.1 - 0.12 12.2 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4330) HTH_23 PF13384.1 EIE81730.1 - 0.12 12.0 2.9 1.7 8.3 0.2 2.5 2 0 0 2 2 2 0 Homeodomain-like domain HTH_21 PF13276.1 EIE81730.1 - 0.18 11.7 3.2 0.61 10.1 0.1 2.3 2 0 0 2 2 2 0 HTH-like domain Retrotrans_gag PF03732.12 EIE81732.1 - 0.062 13.3 0.1 0.062 13.3 0.0 2.1 2 0 0 2 2 2 0 Retrotransposon gag protein Cut8_M PF14483.1 EIE81733.1 - 0.047 13.4 0.1 0.22 11.3 0.0 2.1 2 0 0 2 2 2 0 Cut8 dimerisation domain GCR1_C PF12550.3 EIE81734.1 - 1.5e-24 85.6 0.9 1.5e-23 82.4 0.3 2.7 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes DDE_3 PF13358.1 EIE81736.1 - 5.4e-21 74.8 0.0 1.1e-20 73.8 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE81736.1 - 1.1e-15 57.4 1.9 2.8e-15 56.1 0.3 2.3 3 0 0 3 3 2 1 Transposase HTH_29 PF13551.1 EIE81736.1 - 2.7e-06 27.5 0.2 8.6e-06 25.8 0.2 1.9 2 0 0 2 2 1 1 Winged helix-turn helix HTH_38 PF13936.1 EIE81736.1 - 1.2e-05 24.7 0.1 3.3e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.1 EIE81736.1 - 7.6e-05 22.2 0.1 0.0028 17.2 0.0 2.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.1 EIE81736.1 - 8.8e-05 23.2 2.8 0.02 15.6 0.1 3.7 4 0 0 4 4 3 1 Homeodomain-like domain Sigma70_r4_2 PF08281.7 EIE81736.1 - 0.00054 19.3 0.6 0.024 14.0 0.0 3.2 4 0 0 4 4 4 1 Sigma-70, region 4 HTH_28 PF13518.1 EIE81736.1 - 0.0013 18.7 0.0 0.0056 16.6 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_21 PF13276.1 EIE81736.1 - 0.0014 18.5 0.1 0.13 12.2 0.0 2.8 3 0 0 3 3 3 1 HTH-like domain HTH_7 PF02796.10 EIE81736.1 - 0.0022 17.7 1.1 0.1 12.4 0.0 2.8 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase rve PF00665.21 EIE81736.1 - 0.0045 17.0 0.0 0.014 15.4 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain LacI PF00356.16 EIE81736.1 - 0.018 14.6 1.7 2.8 7.6 0.2 2.7 3 0 0 3 3 3 0 Bacterial regulatory proteins, lacI family HTH_Tnp_4 PF13613.1 EIE81736.1 - 0.022 14.2 0.1 0.057 12.9 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease CPSase_L_D3 PF02787.14 EIE81736.1 - 0.058 13.1 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain HTH_36 PF13730.1 EIE81736.1 - 0.074 13.1 0.4 4.1 7.6 0.0 2.9 3 0 0 3 3 2 0 Helix-turn-helix domain Sigma70_r4 PF04545.11 EIE81736.1 - 0.1 11.9 0.2 0.79 9.0 0.0 2.6 4 0 0 4 4 4 0 Sigma-70, region 4 HTH_Tnp_ISL3 PF13542.1 EIE81736.1 - 0.15 11.2 2.5 8.4 5.6 0.0 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 HTH_17 PF12728.2 EIE81736.1 - 0.2 11.9 2.4 15 5.9 0.1 3.2 3 0 0 3 3 3 0 Helix-turn-helix domain rve PF00665.21 EIE81737.1 - 3.4e-42 143.3 0.0 6.5e-22 77.8 0.0 3.9 4 0 0 4 4 4 2 Integrase core domain RVT_1 PF00078.22 EIE81737.1 - 3.8e-34 117.9 0.5 2.9e-16 59.4 0.1 2.6 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE81737.1 - 6.6e-21 73.7 3.8 1.6e-10 40.5 0.1 2.8 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.1 EIE81737.1 - 1.5e-14 54.2 0.2 2.9e-06 27.7 0.0 3.0 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.1 EIE81737.1 - 9.8e-10 38.1 0.0 0.0012 18.6 0.0 2.5 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.12 EIE81737.1 - 1.1e-09 38.2 6.7 5.4e-05 23.1 0.0 4.5 5 0 0 5 5 5 2 Retrotransposon gag protein RVP PF00077.15 EIE81737.1 - 2.5e-08 33.7 1.7 4e-05 23.4 0.1 3.4 3 0 0 3 3 3 2 Retroviral aspartyl protease Asp_protease PF09668.5 EIE81737.1 - 0.00061 19.3 0.8 0.68 9.5 0.1 3.2 3 0 0 3 3 3 2 Aspartyl protease zf-H2C2 PF09337.5 EIE81737.1 - 0.019 14.3 1.0 0.062 12.7 0.0 2.5 2 0 0 2 2 2 0 His(2)-Cys(2) zinc finger RVP_2 PF08284.6 EIE81737.1 - 0.067 13.1 0.7 3 7.7 0.0 2.6 2 0 0 2 2 2 0 Retroviral aspartyl protease Tudor-knot PF11717.3 EIE81737.1 - 0.15 11.7 8.8 0.18 11.5 0.1 3.3 3 0 0 3 3 3 0 RNA binding activity-knot of a chromodomain IncA PF04156.9 EIE81737.1 - 8.9 5.8 6.2 24 4.4 4.3 1.7 1 0 0 1 1 1 0 IncA protein FHA PF00498.21 EIE81739.1 - 1.8e-11 43.9 0.5 4.2e-11 42.7 0.1 1.8 2 0 0 2 2 2 1 FHA domain Peptidase_S9 PF00326.16 EIE81743.1 - 9.2e-13 47.9 0.2 1.9e-12 46.8 0.1 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family DPPIV_N PF00930.16 EIE81743.1 - 0.0054 15.3 0.0 0.0075 14.8 0.0 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region PP2C PF00481.16 EIE81744.1 - 3.4e-53 180.6 0.0 5.8e-53 179.8 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.2 EIE81744.1 - 1.2e-43 146.1 71.0 7e-06 25.5 0.1 12.8 5 3 9 15 15 15 13 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EIE81744.1 - 6.3e-36 121.9 63.4 4.1e-08 32.8 2.5 10.3 3 3 10 13 13 13 11 Leucine rich repeat Guanylate_cyc PF00211.15 EIE81744.1 - 4.4e-30 104.3 0.0 1e-29 103.1 0.0 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.28 EIE81744.1 - 1.4e-25 85.3 54.2 0.0085 15.9 0.5 18.1 18 1 1 19 19 19 9 Leucine Rich Repeat LRR_7 PF13504.1 EIE81744.1 - 1.3e-12 45.7 55.2 0.18 12.1 0.7 17.3 17 0 0 17 17 17 2 Leucine rich repeat LRR_6 PF13516.1 EIE81744.1 - 0.00053 19.7 58.7 0.48 10.6 0.2 15.1 16 1 0 16 16 16 3 Leucine Rich repeat LRR_9 PF14580.1 EIE81744.1 - 0.00056 19.5 10.4 0.0073 15.8 0.1 3.8 2 1 1 3 3 3 2 Leucine-rich repeat RA PF00788.18 EIE81744.1 - 0.0018 18.7 0.4 0.019 15.4 0.0 2.6 2 1 1 3 3 3 1 Ras association (RalGDS/AF-6) domain PP2C_2 PF13672.1 EIE81744.1 - 0.07 12.5 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein phosphatase 2C TauD PF02668.11 EIE81745.1 - 9.4e-56 189.3 0.4 1.1e-55 189.0 0.3 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Kinesin PF00225.18 EIE81747.1 - 5.3e-89 298.2 11.3 4.5e-56 189.9 1.0 2.9 2 1 1 3 3 3 2 Kinesin motor domain DUF3694 PF12473.3 EIE81747.1 - 4.7e-32 110.5 0.0 1.5e-31 108.9 0.0 1.9 1 0 0 1 1 1 1 Kinesin protein KIF1B PF12423.3 EIE81747.1 - 5e-08 32.8 0.2 1.2e-07 31.5 0.1 1.7 1 0 0 1 1 1 1 Kinesin protein 1B FHA PF00498.21 EIE81747.1 - 2.7e-06 27.4 0.1 2e-05 24.5 0.1 2.5 2 0 0 2 2 2 1 FHA domain tRNA-synt_1c PF00749.16 EIE81750.1 - 2.2e-109 364.9 0.1 3.8e-109 364.1 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain DUF4042 PF13251.1 EIE81750.1 - 0.075 12.4 0.1 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4042) CAP_N PF01213.14 EIE81751.1 - 9.3e-87 291.2 13.5 1.9e-86 290.1 9.3 1.5 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 EIE81751.1 - 1.4e-56 190.2 10.0 2e-56 189.7 6.9 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 EIE81751.1 - 7.7e-05 22.0 4.1 0.00049 19.4 2.6 2.2 1 1 1 2 2 2 2 Tubulin binding cofactor C Mito_fiss_reg PF05308.6 EIE81751.1 - 3.3 7.0 14.6 12 5.2 10.1 2.0 1 1 0 1 1 1 0 Mitochondrial fission regulator ELO PF01151.13 EIE81752.1 - 1.2e-68 231.1 11.8 1.5e-68 230.8 8.2 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family FecCD PF01032.13 EIE81752.1 - 0.031 13.0 0.8 0.65 8.7 0.0 2.0 2 0 0 2 2 2 0 FecCD transport family Sec2p PF06428.6 EIE81754.1 - 0.006 16.3 1.4 0.0083 15.9 0.9 1.1 1 0 0 1 1 1 1 GDP/GTP exchange factor Sec2p DUF812 PF05667.6 EIE81754.1 - 0.0062 15.1 2.4 0.0074 14.8 1.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF812) ANTH PF07651.11 EIE81754.1 - 0.016 13.9 0.1 0.025 13.2 0.1 1.3 1 0 0 1 1 1 0 ANTH domain Bap31 PF05529.7 EIE81754.1 - 0.028 13.8 3.3 0.059 12.8 2.3 1.5 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Lin-8 PF03353.10 EIE81754.1 - 0.031 13.5 1.0 0.038 13.2 0.7 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist ABC_tran_2 PF12848.2 EIE81754.1 - 0.035 13.9 3.0 0.071 12.9 2.1 1.5 1 0 0 1 1 1 0 ABC transporter PEP-utilisers_N PF05524.8 EIE81754.1 - 0.043 13.6 0.8 0.058 13.1 0.6 1.2 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal XhlA PF10779.4 EIE81754.1 - 0.05 13.5 0.8 0.089 12.7 0.6 1.4 1 0 0 1 1 1 0 Haemolysin XhlA PDCD2_C PF04194.8 EIE81754.1 - 0.09 12.3 1.5 0.11 12.0 1.0 1.1 1 0 0 1 1 1 0 Programmed cell death protein 2, C-terminal putative domain CHD5 PF04420.9 EIE81754.1 - 0.11 12.0 3.8 0.11 12.1 1.4 1.8 1 1 1 2 2 2 0 CHD5-like protein Fib_alpha PF08702.5 EIE81754.1 - 0.13 12.3 2.1 0.17 12.0 1.5 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family COG5 PF10392.4 EIE81754.1 - 0.14 12.1 1.9 0.22 11.4 1.3 1.3 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Uds1 PF15456.1 EIE81754.1 - 0.23 11.4 4.7 0.38 10.7 3.3 1.3 1 0 0 1 1 1 0 Up-regulated During Septation bZIP_2 PF07716.10 EIE81754.1 - 0.32 10.8 3.5 0.67 9.8 2.4 1.6 1 0 0 1 1 1 0 Basic region leucine zipper TORC_N PF12884.2 EIE81754.1 - 0.53 10.8 4.8 0.39 11.2 0.9 2.0 1 1 1 2 2 2 0 Transducer of regulated CREB activity, N terminus FlxA PF14282.1 EIE81754.1 - 0.72 9.8 11.7 0.78 9.7 7.4 1.5 1 1 0 1 1 1 0 FlxA-like protein SlyX PF04102.7 EIE81754.1 - 1.9 8.8 4.5 5.1 7.5 1.2 2.2 1 1 1 2 2 2 0 SlyX CTP_transf_2 PF01467.21 EIE81755.1 - 3.9e-07 30.2 0.0 4.2e-07 30.1 0.0 1.0 1 0 0 1 1 1 1 Cytidylyltransferase PNRC PF15365.1 EIE81756.1 - 5.9e-09 35.7 2.9 5.9e-09 35.7 2.0 2.8 2 2 1 3 3 3 1 Proline-rich nuclear receptor coactivator DUF3959 PF13105.1 EIE81756.1 - 1.4 8.2 5.5 1.8 7.8 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) DUF4551 PF15087.1 EIE81756.1 - 1.8 6.8 7.2 2.2 6.5 5.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) MutS_V PF00488.16 EIE81757.1 - 2.6e-72 243.0 0.2 5.2e-72 242.0 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EIE81757.1 - 6.2e-42 143.6 1.2 3.4e-41 141.3 0.6 2.1 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.12 EIE81757.1 - 1.1e-10 41.7 0.0 3.5e-10 40.0 0.0 1.9 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 EIE81757.1 - 4.8e-07 29.8 0.8 1.8e-06 27.9 0.5 2.0 1 0 0 1 1 1 1 MutS family domain IV AAA_29 PF13555.1 EIE81757.1 - 0.12 11.9 0.0 0.42 10.1 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain bZIP_1 PF00170.16 EIE81758.1 - 5.1e-09 35.9 10.2 5.1e-09 35.9 7.1 1.7 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EIE81758.1 - 5.1e-07 29.4 13.0 5.1e-07 29.4 9.0 1.7 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 EIE81758.1 - 0.00032 20.9 7.1 0.00059 20.0 4.9 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor DUF342 PF03961.8 EIE81758.1 - 0.14 10.5 3.6 0.17 10.2 2.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) IncA PF04156.9 EIE81758.1 - 2.4 7.7 7.8 3.3 7.2 5.4 1.2 1 0 0 1 1 1 0 IncA protein TSC22 PF01166.13 EIE81758.1 - 4.7 7.2 6.9 1.1 9.2 1.8 2.2 2 1 0 2 2 2 0 TSC-22/dip/bun family MRF_C1 PF13887.1 EIE81759.1 - 0.049 12.6 0.0 0.067 12.2 0.0 1.2 1 0 0 1 1 1 0 Myelin gene regulatory factor -C-terminal domain 1 G10 PF01125.12 EIE81760.1 - 4.2e-59 198.2 1.8 6.9e-59 197.5 1.3 1.3 1 0 0 1 1 1 1 G10 protein Med6 PF04934.9 EIE81762.1 - 1.8e-38 131.2 0.3 2.1e-38 131.0 0.2 1.0 1 0 0 1 1 1 1 MED6 mediator sub complex component Pho88 PF10032.4 EIE81763.1 - 6.3e-25 87.5 0.1 6.8e-25 87.4 0.1 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) HTH_29 PF13551.1 EIE81764.1 - 2.7e-08 33.9 0.0 7.7e-08 32.4 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.1 EIE81764.1 - 7.6e-06 25.8 1.6 8.3e-05 22.5 0.0 3.0 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_Tnp_1 PF01527.15 EIE81764.1 - 1.8e-05 24.5 0.6 0.0013 18.6 0.1 2.6 2 1 0 2 2 2 1 Transposase HTH_32 PF13565.1 EIE81764.1 - 6e-05 23.7 0.3 0.00027 21.6 0.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.1 EIE81764.1 - 0.0014 18.2 0.7 0.026 14.1 0.0 3.0 2 1 1 3 3 3 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.13 EIE81764.1 - 0.01 15.8 0.2 0.02 14.9 0.1 1.5 1 0 0 1 1 1 0 Transposase Terminase_5 PF06056.7 EIE81764.1 - 0.044 13.3 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) HTH_17 PF12728.2 EIE81764.1 - 0.053 13.7 0.0 2.2 8.5 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain TylF PF05711.6 EIE81764.1 - 0.083 11.9 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Macrocin-O-methyltransferase (TylF) RNase_T PF00929.19 EIE81764.1 - 0.1 12.8 0.1 0.23 11.7 0.0 1.6 1 1 1 2 2 2 0 Exonuclease HTH_30 PF13556.1 EIE81764.1 - 0.1 12.1 0.1 0.24 11.0 0.1 1.6 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain zf-MYND PF01753.13 EIE81765.1 - 0.00019 21.2 14.0 0.00019 21.2 9.7 2.7 2 0 0 2 2 2 1 MYND finger SET PF00856.23 EIE81765.1 - 0.0037 17.5 0.2 0.0082 16.4 0.1 1.7 1 1 0 1 1 1 1 SET domain YyzF PF14116.1 EIE81765.1 - 0.1 12.5 3.1 5.6 6.9 0.1 2.8 2 0 0 2 2 2 0 YyzF-like protein CtIP_N PF10482.4 EIE81765.1 - 2.7 7.7 7.4 0.8 9.4 0.8 2.6 3 0 0 3 3 3 0 Tumour-suppressor protein CtIP N-terminal domain ABC_tran PF00005.22 EIE81766.1 - 5.5e-45 153.0 0.1 1e-22 80.9 0.0 3.9 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EIE81766.1 - 4.9e-15 56.2 0.5 0.0058 16.6 0.4 4.7 2 2 1 4 4 4 3 AAA domain SMC_N PF02463.14 EIE81766.1 - 1.7e-13 50.3 0.0 0.011 14.9 0.0 4.5 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EIE81766.1 - 1.1e-08 35.9 0.4 0.00076 20.2 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_28 PF13521.1 EIE81766.1 - 4.6e-08 33.1 0.1 0.017 15.0 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 EIE81766.1 - 5.3e-08 33.0 0.0 0.017 15.2 0.0 4.5 5 0 0 5 5 5 2 AAA domain AAA_29 PF13555.1 EIE81766.1 - 8.4e-08 31.6 0.0 0.011 15.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA PF00004.24 EIE81766.1 - 5e-07 29.9 0.1 0.049 13.8 0.0 4.3 4 0 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 EIE81766.1 - 5.6e-07 28.8 0.0 0.0025 17.0 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Miro PF08477.8 EIE81766.1 - 1.8e-06 28.4 0.0 0.1 13.0 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein MMR_HSR1 PF01926.18 EIE81766.1 - 2.2e-06 27.6 0.0 0.02 14.8 0.0 3.1 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_15 PF13175.1 EIE81766.1 - 3.3e-06 26.4 1.2 0.69 8.9 0.0 4.2 4 0 0 4 4 4 2 AAA ATPase domain SbcCD_C PF13558.1 EIE81766.1 - 6.5e-06 25.9 0.0 0.0094 15.8 0.0 3.1 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.17 EIE81766.1 - 1e-05 25.6 0.0 0.26 11.4 0.0 2.7 2 0 0 2 2 2 2 RNA helicase ArgK PF03308.11 EIE81766.1 - 1.2e-05 24.2 0.1 0.052 12.3 0.0 2.5 2 0 0 2 2 2 2 ArgK protein NACHT PF05729.7 EIE81766.1 - 1.7e-05 24.5 1.4 0.048 13.3 0.0 3.4 3 1 0 3 3 3 2 NACHT domain Chromo PF00385.19 EIE81766.1 - 1.7e-05 24.3 0.2 5.6e-05 22.7 0.1 2.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain MobB PF03205.9 EIE81766.1 - 2.1e-05 24.2 0.0 0.13 11.9 0.0 3.0 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 EIE81766.1 - 3.7e-05 24.0 0.1 0.11 12.7 0.1 3.0 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EIE81766.1 - 4.6e-05 23.4 0.2 0.08 12.9 0.0 3.2 3 1 0 3 3 2 1 AAA ATPase domain AAA_33 PF13671.1 EIE81766.1 - 6.5e-05 22.8 0.0 0.33 10.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 EIE81766.1 - 7.4e-05 22.3 0.0 0.52 9.7 0.0 3.4 4 1 0 4 4 3 2 AAA-like domain DUF815 PF05673.8 EIE81766.1 - 9.1e-05 21.5 0.0 0.19 10.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_14 PF13173.1 EIE81766.1 - 0.00012 22.0 0.0 0.13 12.1 0.0 3.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 EIE81766.1 - 0.00034 20.2 0.1 2.2 7.8 0.0 3.7 3 0 0 3 3 3 1 AAA domain PduV-EutP PF10662.4 EIE81766.1 - 0.00047 19.6 0.0 0.73 9.3 0.0 2.9 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Zeta_toxin PF06414.7 EIE81766.1 - 0.00082 18.5 0.6 3.3 6.7 0.0 3.5 3 0 0 3 3 3 1 Zeta toxin ATP-synt_ab PF00006.20 EIE81766.1 - 0.00096 18.7 0.1 0.23 10.9 0.0 2.7 3 0 0 3 3 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_13 PF13166.1 EIE81766.1 - 0.0019 16.7 0.3 3.4 6.0 0.0 3.5 4 0 0 4 4 4 1 AAA domain Arch_ATPase PF01637.13 EIE81766.1 - 0.0024 17.6 1.5 0.84 9.2 0.0 3.3 3 0 0 3 3 2 1 Archaeal ATPase Dynamin_N PF00350.18 EIE81766.1 - 0.0025 17.6 0.2 0.5 10.1 0.0 2.9 3 0 0 3 3 2 1 Dynamin family HEAT PF02985.17 EIE81766.1 - 0.0046 16.9 0.1 10 6.4 0.0 3.9 3 0 0 3 3 3 0 HEAT repeat AAA_25 PF13481.1 EIE81766.1 - 0.0085 15.5 0.0 5.4 6.3 0.0 3.5 4 0 0 4 4 4 0 AAA domain AAA_23 PF13476.1 EIE81766.1 - 0.013 15.8 15.5 0.12 12.6 0.6 3.8 5 1 0 5 5 3 0 AAA domain Viral_helicase1 PF01443.13 EIE81766.1 - 0.014 14.9 0.0 0.41 10.1 0.0 2.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_5 PF07728.9 EIE81766.1 - 0.016 14.9 0.1 9.9 5.8 0.0 3.8 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) MutS_V PF00488.16 EIE81766.1 - 0.025 13.9 0.1 5.2 6.4 0.0 2.3 2 0 0 2 2 2 0 MutS domain V NUC173 PF08161.7 EIE81766.1 - 0.028 13.7 0.1 0.11 11.7 0.0 2.0 1 1 0 1 1 1 0 NUC173 domain PRK PF00485.13 EIE81766.1 - 0.039 13.4 0.0 2.8 7.4 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family FtsK_SpoIIIE PF01580.13 EIE81766.1 - 0.043 13.2 0.0 23 4.3 0.0 3.3 3 0 0 3 3 3 0 FtsK/SpoIIIE family DUF87 PF01935.12 EIE81766.1 - 0.045 13.5 6.5 0.56 9.9 0.0 3.6 4 0 0 4 4 3 0 Domain of unknown function DUF87 HEAT_EZ PF13513.1 EIE81766.1 - 0.14 12.6 3.6 27 5.3 0.0 4.3 4 1 0 4 4 3 0 HEAT-like repeat DUF2393 PF09624.5 EIE81767.1 - 0.044 13.3 0.0 0.051 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2393) zf-C2H2 PF00096.21 EIE81768.1 - 5.5e-10 38.9 22.0 9e-05 22.5 0.2 4.8 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIE81768.1 - 4.1e-08 33.1 20.2 5.8e-05 23.1 0.5 3.9 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EIE81768.1 - 0.00092 19.3 19.6 0.0049 17.1 0.1 4.2 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EIE81768.1 - 0.086 13.0 4.9 13 6.0 1.4 3.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding PBP1_TM PF14812.1 EIE81768.1 - 5.3 7.4 12.3 1.2 9.4 0.9 2.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CUE PF02845.11 EIE81769.1 - 6e-10 38.4 0.4 1.3e-09 37.3 0.3 1.6 1 0 0 1 1 1 1 CUE domain Syntaxin-6_N PF09177.6 EIE81770.1 - 1.3e-18 67.1 2.1 3.1e-18 65.9 0.7 1.9 1 1 1 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.14 EIE81770.1 - 5.7e-11 41.9 2.8 5.7e-11 41.9 1.9 2.6 3 0 0 3 3 3 1 SNARE domain UPF0184 PF03670.8 EIE81770.1 - 0.029 14.5 6.8 0.81 9.8 0.6 2.8 2 2 0 2 2 2 0 Uncharacterised protein family (UPF0184) AAA_13 PF13166.1 EIE81770.1 - 0.066 11.6 2.2 0.11 10.9 1.5 1.3 1 1 0 1 1 1 0 AAA domain Snapin_Pallidin PF14712.1 EIE81770.1 - 0.075 13.3 2.8 2.6 8.4 0.1 2.4 1 1 1 2 2 2 0 Snapin/Pallidin Allexi_40kDa PF05549.6 EIE81770.1 - 0.17 11.1 1.4 0.23 10.6 0.5 1.5 1 1 1 2 2 2 0 Allexivirus 40kDa protein Uso1_p115_C PF04871.8 EIE81770.1 - 0.18 11.7 2.3 0.93 9.4 1.6 2.1 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region CENP-Q PF13094.1 EIE81770.1 - 0.29 11.1 4.8 0.9 9.5 3.3 1.8 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit TBPIP PF07106.8 EIE81770.1 - 0.41 10.1 3.3 0.35 10.3 0.6 1.8 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) NPV_P10 PF05531.7 EIE81770.1 - 0.89 9.8 5.1 23 5.3 3.0 2.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein HLH PF00010.21 EIE81773.1 - 3.5e-09 36.2 3.8 1.3e-08 34.3 2.6 2.1 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF3474 PF11960.3 EIE81773.1 - 1.2 9.1 6.0 2 8.4 4.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3474) VPS11_C PF12451.3 EIE81773.1 - 4.2 7.3 9.8 0.18 11.6 1.6 2.6 2 0 0 2 2 2 0 Vacuolar protein sorting protein 11 C terminal TrbI_Ftype PF09677.5 EIE81773.1 - 4.7 7.1 5.4 0.44 10.4 0.4 1.8 2 0 0 2 2 2 0 Type-F conjugative transfer system protein (TrbI_Ftype) Dmrt1 PF12374.3 EIE81773.1 - 8.4 6.8 10.0 1 9.7 1.3 2.4 1 1 1 2 2 2 0 Double-sex mab3 related transcription factor 1 SNF2_N PF00176.18 EIE81774.1 - 4.4e-75 252.2 0.6 4.4e-75 252.2 0.4 2.2 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EIE81774.1 - 8.2e-16 57.6 0.0 3e-15 55.8 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HSA PF07529.8 EIE81774.1 - 2.2e-08 33.7 3.7 2.2e-08 33.7 2.5 3.2 1 1 1 2 2 2 1 HSA DEAD PF00270.24 EIE81774.1 - 1.2e-05 24.8 0.0 6.6e-05 22.4 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase PHD PF00628.24 EIE81775.1 - 1.7e-09 37.1 12.9 7.8e-09 35.0 7.2 2.4 2 0 0 2 2 2 1 PHD-finger zf-C2H2_jaz PF12171.3 EIE81775.1 - 0.0022 18.1 0.1 0.0052 16.8 0.1 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 EIE81775.1 - 0.016 15.5 3.2 0.016 15.5 2.2 3.1 3 0 0 3 3 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EIE81775.1 - 0.065 13.6 4.0 0.065 13.6 2.8 2.9 3 0 0 3 3 3 0 Zinc finger, C2H2 type zinc_ribbon_4 PF13717.1 EIE81775.1 - 0.41 10.3 7.7 3.6 7.3 0.3 3.6 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EIE81775.1 - 0.49 10.0 7.8 3.1 7.4 0.3 3.6 3 0 0 3 3 3 0 zinc-ribbon domain PHD_2 PF13831.1 EIE81775.1 - 0.53 9.6 9.3 0.51 9.7 4.0 2.3 2 0 0 2 2 2 0 PHD-finger zf-RING_2 PF13639.1 EIE81775.1 - 0.7 9.7 16.6 0.22 11.3 7.4 2.2 2 0 0 2 2 2 0 Ring finger domain C1_3 PF07649.7 EIE81775.1 - 1.7 8.7 9.1 4.2 7.4 0.9 3.3 3 0 0 3 3 3 0 C1-like domain Tnp_zf-ribbon_2 PF13842.1 EIE81775.1 - 2 8.9 15.9 1.7e+02 2.7 1.1 3.3 1 1 1 2 2 1 0 DDE_Tnp_1-like zinc-ribbon zf-RING-like PF08746.6 EIE81775.1 - 9.1 6.3 17.2 1 9.4 8.0 2.2 1 1 1 2 2 2 0 RING-like domain LAG1-DNAbind PF09271.6 EIE81776.1 - 6.7e-36 123.8 0.4 1.6e-35 122.6 0.3 1.7 1 0 0 1 1 1 1 LAG1, DNA binding BTD PF09270.5 EIE81776.1 - 1.8e-22 79.8 0.2 2e-18 66.6 0.0 3.3 2 1 0 2 2 2 2 Beta-trefoil DNA-binding domain TIG PF01833.19 EIE81776.1 - 4.9e-06 26.4 0.3 1.8e-05 24.6 0.2 2.0 1 0 0 1 1 1 1 IPT/TIG domain DUF2003 PF09404.5 EIE81777.1 - 3.8e-27 94.7 0.7 1.1e-25 89.9 0.5 2.2 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF2003) Sulfate_transp PF00916.15 EIE81778.1 - 1.1e-47 162.4 2.2 1.6e-47 161.8 1.5 1.3 1 0 0 1 1 1 1 Sulfate transporter family STAS PF01740.16 EIE81778.1 - 1.7e-14 53.2 0.0 3.2e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 STAS domain Xan_ur_permease PF00860.15 EIE81778.1 - 4.8e-05 22.0 3.7 4.8e-05 22.0 2.6 1.8 2 0 0 2 2 2 1 Permease family STAS_2 PF13466.1 EIE81778.1 - 0.015 15.3 0.5 0.042 13.8 0.0 1.9 2 0 0 2 2 2 0 STAS domain TMEM61 PF15105.1 EIE81779.1 - 0.18 11.2 1.0 0.27 10.7 0.7 1.2 1 0 0 1 1 1 0 TMEM61 protein family Aa_trans PF01490.13 EIE81780.1 - 6.5e-53 179.6 27.7 1.4e-39 135.8 11.1 2.0 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein MIG-14_Wnt-bd PF06664.7 EIE81780.1 - 2.3 6.9 11.8 0.05 12.4 1.8 2.4 2 1 1 3 3 3 0 Wnt-binding factor required for Wnt secretion DUF1230 PF06799.6 EIE81780.1 - 2.4 8.0 5.7 5.2 6.9 0.0 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF1230) WD40 PF00400.27 EIE81782.1 - 5.6e-44 146.5 19.4 1.1e-08 34.6 0.4 6.7 6 1 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 EIE81782.1 - 1.9e-10 39.5 5.9 0.0074 14.4 0.0 4.3 2 1 2 4 4 4 4 Nucleoporin Nup120/160 F-box-like PF12937.2 EIE81782.1 - 4.4e-08 32.7 0.3 9.2e-08 31.6 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIE81782.1 - 1.7e-07 30.7 0.1 3.8e-07 29.5 0.1 1.7 1 0 0 1 1 1 1 F-box domain PQQ_2 PF13360.1 EIE81782.1 - 0.0012 18.3 0.1 0.43 9.9 0.0 2.5 2 1 0 2 2 2 1 PQQ-like domain HSP70 PF00012.15 EIE81783.1 - 5.2e-166 553.0 3.6 8.2e-166 552.4 2.5 1.3 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EIE81783.1 - 1.5e-12 46.7 0.2 2.7e-11 42.6 0.0 2.2 2 0 0 2 2 2 1 MreB/Mbl protein Imm6 PF14434.1 EIE81783.1 - 0.026 14.2 0.1 0.97 9.1 0.0 2.5 2 0 0 2 2 2 0 Immunity protein Imm6 FtsA PF14450.1 EIE81783.1 - 0.034 13.9 3.1 5.8 6.7 0.1 3.4 2 1 0 2 2 2 0 Cell division protein FtsA Amidohydro_1 PF01979.15 EIE81784.1 - 5.1e-60 203.8 3.6 8.2e-60 203.1 2.5 1.4 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.15 EIE81784.1 - 2.6e-54 182.5 2.0 5e-54 181.5 1.4 1.5 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.15 EIE81784.1 - 9.1e-42 140.9 0.0 1.7e-41 140.0 0.0 1.5 1 0 0 1 1 1 1 Urease beta subunit Urease_gamma PF00547.13 EIE81784.1 - 2.7e-18 65.8 0.1 7.5e-18 64.3 0.1 1.8 1 0 0 1 1 1 1 Urease, gamma subunit Amidohydro_5 PF13594.1 EIE81784.1 - 0.00019 21.1 2.4 0.0007 19.3 1.6 2.0 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EIE81784.1 - 0.0017 17.6 0.9 0.006 15.8 0.2 2.1 2 1 0 2 2 2 1 Amidohydrolase family Sipho_Gp157 PF05565.6 EIE81785.1 - 0.012 15.1 6.1 0.013 15.0 4.3 1.1 1 0 0 1 1 1 0 Siphovirus Gp157 DUF770 PF05591.7 EIE81785.1 - 0.052 13.1 0.7 0.068 12.7 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF770) Lipoprotein_20 PF13942.1 EIE81785.1 - 0.058 12.9 0.2 0.066 12.7 0.2 1.1 1 0 0 1 1 1 0 YfhG lipoprotein Cauli_AT PF03233.8 EIE81785.1 - 0.068 12.8 2.8 0.078 12.6 1.9 1.1 1 0 0 1 1 1 0 Aphid transmission protein eIF3_p135 PF12807.2 EIE81785.1 - 0.068 13.1 1.0 0.073 13.0 0.7 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit 135 TMF_DNA_bd PF12329.3 EIE81785.1 - 0.078 12.7 5.3 0.13 12.1 3.7 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Phage_GP20 PF06810.6 EIE81785.1 - 0.28 10.6 6.6 0.84 9.0 2.9 2.0 1 1 1 2 2 2 0 Phage minor structural protein GP20 AF1Q PF15017.1 EIE81787.1 - 2.9 7.8 8.0 2.3 8.1 4.4 1.7 2 0 0 2 2 2 0 Drug resistance and apoptosis regulator CP2 PF04516.10 EIE81789.1 - 1.3e-36 125.8 0.2 1.3e-36 125.8 0.1 1.8 2 1 0 2 2 2 1 CP2 transcription factor p450 PF00067.17 EIE81790.1 - 4.4e-62 210.0 0.1 2.8e-34 118.4 0.1 2.0 2 0 0 2 2 2 2 Cytochrome P450 Inositol_P PF00459.20 EIE81791.1 - 9.5e-60 202.1 1.0 9.5e-60 202.1 0.7 3.9 3 2 1 4 4 4 1 Inositol monophosphatase family RRM_5 PF13893.1 EIE81791.1 - 1.4e-05 24.8 0.0 3.9e-05 23.3 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SAP PF02037.22 EIE81791.1 - 6.1e-05 22.4 0.9 0.00017 20.9 0.1 2.3 3 0 0 3 3 3 1 SAP domain RRM_1 PF00076.17 EIE81791.1 - 0.0025 17.3 0.0 0.0088 15.6 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Complex1_30kDa PF00329.14 EIE81792.1 - 2.6e-35 120.7 0.0 3.8e-35 120.2 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit DUF3355 PF11835.3 EIE81792.1 - 0.083 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3355) HlyIII PF03006.15 EIE81793.1 - 2e-16 60.1 2.7 2.9e-16 59.5 1.9 1.3 1 0 0 1 1 1 1 Haemolysin-III related DDE_3 PF13358.1 EIE81794.1 - 3.7e-29 101.3 0.0 5.6e-29 100.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.14 EIE81794.1 - 0.0014 17.8 0.0 0.027 13.6 0.0 2.0 1 1 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE81797.1 - 1.2e-23 83.4 0.0 3e-23 82.1 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE81797.1 - 1.4e-15 57.2 0.3 3.9e-15 55.8 0.2 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE81797.1 - 3.9e-11 42.4 1.1 9.3e-11 41.2 0.7 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.12 EIE81797.1 - 0.00052 20.0 1.2 0.0026 17.7 0.8 2.3 1 0 0 1 1 1 1 Retrotransposon gag protein zf-H2C2 PF09337.5 EIE81797.1 - 0.0014 17.9 0.1 0.004 16.5 0.1 1.9 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger UBN2_2 PF14227.1 EIE81797.1 - 0.0021 17.6 1.8 0.03 13.8 0.0 3.1 3 0 0 3 3 3 1 gag-polypeptide of LTR copia-type rve_3 PF13683.1 EIE81797.1 - 0.0071 15.8 0.2 0.048 13.1 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain UBN2 PF14223.1 EIE81797.1 - 0.051 13.3 0.2 0.21 11.3 0.1 2.1 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type Y_phosphatase PF00102.22 EIE81798.1 - 1.5e-67 227.4 2.8 1.5e-67 227.4 1.9 1.9 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Rhodanese PF00581.15 EIE81798.1 - 2.5e-12 47.1 0.1 6e-11 42.6 0.0 2.4 2 0 0 2 2 2 1 Rhodanese-like domain Gastrin PF00918.12 EIE81798.1 - 0.028 15.2 1.4 0.57 10.9 0.0 2.7 2 0 0 2 2 2 0 Gastrin/cholecystokinin family DSPc PF00782.15 EIE81798.1 - 0.042 13.4 0.0 0.12 11.9 0.0 1.7 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EIE81798.1 - 0.15 12.3 1.6 0.33 11.1 0.1 2.3 3 0 0 3 3 3 0 Tyrosine phosphatase family NmrA PF05368.8 EIE81799.1 - 2.2e-07 30.3 0.2 3.1e-07 29.9 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EIE81799.1 - 0.002 18.1 0.0 0.0029 17.6 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding GHL6 PF14871.1 EIE81799.1 - 0.036 14.0 0.8 2.2 8.3 0.1 2.4 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase 6 Ribosomal_S8 PF00410.14 EIE81800.1 - 3.4e-29 101.2 0.0 4.7e-29 100.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 plasmid_Toxin PF12703.2 EIE81801.1 - 0.052 13.3 0.0 4.7 7.0 0.0 2.2 2 0 0 2 2 2 0 Toxin of toxin-antitoxin type 1 system PX PF00787.19 EIE81804.1 - 4.5e-07 29.6 0.0 4.5e-07 29.6 0.0 2.1 3 0 0 3 3 3 1 PX domain DivIC PF04977.10 EIE81804.1 - 0.0063 15.9 3.4 0.057 12.9 1.6 2.3 2 0 0 2 2 2 1 Septum formation initiator Myosin_tail_1 PF01576.14 EIE81804.1 - 0.084 10.5 2.0 1.1 6.9 0.5 2.0 2 0 0 2 2 2 0 Myosin tail bZIP_1 PF00170.16 EIE81804.1 - 0.087 12.7 2.2 0.19 11.6 1.5 1.6 1 0 0 1 1 1 0 bZIP transcription factor HALZ PF02183.13 EIE81804.1 - 0.15 11.7 1.4 0.38 10.4 1.0 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper NYD-SP28_assoc PF14775.1 EIE81804.1 - 0.35 10.5 2.5 0.8 9.4 1.7 1.6 1 0 0 1 1 1 0 Sperm tail C-terminal domain bZIP_2 PF07716.10 EIE81804.1 - 0.89 9.4 3.3 0.78 9.6 1.3 1.6 2 0 0 2 2 2 0 Basic region leucine zipper RhoGAP PF00620.22 EIE81805.1 - 2.7e-27 95.2 0.3 4.6e-27 94.5 0.2 1.3 1 0 0 1 1 1 1 RhoGAP domain Nop52 PF05997.7 EIE81805.1 - 0.01 15.3 0.1 0.018 14.5 0.1 1.4 1 0 0 1 1 1 0 Nucleolar protein,Nop52 Pkinase PF00069.20 EIE81806.1 - 1.2e-52 178.6 0.1 2.1e-52 177.8 0.1 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE81806.1 - 1.6e-23 83.1 0.0 2.4e-23 82.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIE81806.1 - 0.00014 21.6 0.0 0.0008 19.2 0.0 1.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family RIO1 PF01163.17 EIE81806.1 - 0.005 16.2 0.7 0.0097 15.2 0.5 1.5 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.15 EIE81806.1 - 0.015 14.9 0.7 0.16 11.4 0.0 2.3 2 0 0 2 2 2 0 Choline/ethanolamine kinase Kdo PF06293.9 EIE81806.1 - 0.081 11.9 2.0 0.23 10.4 0.0 2.1 1 1 1 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family HhH-GPD PF00730.20 EIE81807.1 - 1.1e-20 73.9 0.5 2.3e-20 72.8 0.0 1.9 3 0 0 3 3 3 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EIE81807.1 - 3.2e-07 29.6 0.0 9.1e-07 28.2 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.4 EIE81807.1 - 8.7e-05 22.5 5.3 0.00014 21.9 3.7 1.3 1 0 0 1 1 1 1 Iron-sulfur binding domain of endonuclease III DDE_Tnp_1_6 PF13751.1 EIE81807.1 - 0.0093 15.9 0.4 0.0093 15.9 0.3 1.9 2 0 0 2 2 2 1 Transposase DDE domain LMBR1 PF04791.11 EIE81808.1 - 0.0069 15.0 2.6 0.0077 14.8 1.8 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein Parvo_coat PF00740.13 EIE81808.1 - 0.82 8.5 10.1 1 8.2 7.0 1.0 1 0 0 1 1 1 0 Parvovirus coat protein VP2 PPP4R2 PF09184.6 EIE81808.1 - 2.3 7.6 19.8 3.1 7.2 13.7 1.1 1 0 0 1 1 1 0 PPP4R2 Mid2 PF04478.7 EIE81809.1 - 0.0016 17.8 0.1 0.0035 16.7 0.0 1.6 1 1 0 1 1 1 1 Mid2 like cell wall stress sensor Herpes_UL37_2 PF07413.6 EIE81809.1 - 0.019 13.8 0.0 0.026 13.3 0.0 1.2 1 0 0 1 1 1 0 Betaherpesvirus immediate-early glycoprotein UL37 Herpes_gE PF02480.11 EIE81809.1 - 0.026 12.8 0.0 0.036 12.3 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E SKG6 PF08693.5 EIE81809.1 - 0.35 10.2 1.5 1.3 8.4 0.0 2.2 2 0 0 2 2 2 0 Transmembrane alpha-helix domain AAA PF00004.24 EIE81811.1 - 4.5e-67 224.2 0.7 8.7e-45 152.1 0.0 4.3 3 1 0 3 3 3 3 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EIE81811.1 - 1.4e-13 50.4 0.0 6.5e-07 28.6 0.0 2.7 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EIE81811.1 - 8.5e-11 42.1 0.2 2e-05 24.7 0.1 4.3 2 2 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EIE81811.1 - 7.2e-10 38.7 0.8 5.3e-05 22.9 0.1 3.0 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EIE81811.1 - 8e-10 39.0 0.2 7e-05 22.8 0.0 3.2 2 2 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 EIE81811.1 - 4.4e-09 37.2 0.0 7e-05 23.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 EIE81811.1 - 1.9e-07 30.6 0.1 0.013 14.9 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_33 PF13671.1 EIE81811.1 - 3.3e-07 30.2 0.0 0.001 18.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.9 EIE81811.1 - 1.3e-06 28.3 0.0 0.00062 19.7 0.0 3.0 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) Zeta_toxin PF06414.7 EIE81811.1 - 2.2e-06 26.9 0.0 0.017 14.2 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_19 PF13245.1 EIE81811.1 - 3.5e-06 26.6 1.3 0.0021 17.7 0.1 3.5 4 0 0 4 4 3 1 Part of AAA domain TIP49 PF06068.8 EIE81811.1 - 3.9e-06 25.8 0.5 0.043 12.5 0.1 3.2 4 1 0 4 4 4 2 TIP49 C-terminus Mg_chelatase PF01078.16 EIE81811.1 - 6.4e-06 25.4 0.8 0.066 12.3 0.0 2.9 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 EIE81811.1 - 1.4e-05 24.5 0.8 0.49 9.7 0.0 3.5 3 1 0 3 3 3 2 AAA domain Sigma54_activ_2 PF14532.1 EIE81811.1 - 2.7e-05 24.2 0.0 0.15 12.1 0.0 2.8 2 1 0 2 2 2 2 Sigma-54 interaction domain RNA_helicase PF00910.17 EIE81811.1 - 4.8e-05 23.4 0.0 0.54 10.4 0.0 3.4 3 0 0 3 3 3 2 RNA helicase AAA_14 PF13173.1 EIE81811.1 - 0.0001 22.1 0.0 0.0014 18.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EIE81811.1 - 0.00011 22.4 0.1 0.012 15.8 0.0 2.7 2 1 0 2 2 2 1 AAA domain KaiC PF06745.8 EIE81811.1 - 0.00023 20.3 1.7 1.6 7.8 0.0 3.9 2 1 2 4 4 4 2 KaiC AAA_28 PF13521.1 EIE81811.1 - 0.00029 20.8 0.0 0.34 10.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.21 EIE81811.1 - 0.00052 19.5 0.0 3.1 7.2 0.0 3.4 3 0 0 3 3 3 1 Sigma-54 interaction domain NACHT PF05729.7 EIE81811.1 - 0.0015 18.2 0.2 1.6 8.3 0.0 3.3 3 0 0 3 3 3 1 NACHT domain PhoH PF02562.11 EIE81811.1 - 0.0016 17.6 0.2 0.36 10.0 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein Rad17 PF03215.10 EIE81811.1 - 0.0016 17.1 0.1 0.088 11.4 0.0 2.7 2 1 1 3 3 3 1 Rad17 cell cycle checkpoint protein ResIII PF04851.10 EIE81811.1 - 0.0016 18.2 0.0 0.018 14.8 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_3 PF07726.6 EIE81811.1 - 0.0032 17.0 0.0 0.88 9.1 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EIE81811.1 - 0.0051 16.5 0.1 2.4 7.7 0.0 3.1 2 1 1 3 3 3 1 Archaeal ATPase AAA_11 PF13086.1 EIE81811.1 - 0.011 15.3 0.0 0.16 11.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 EIE81811.1 - 0.022 14.3 0.0 1.4 8.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.20 EIE81811.1 - 0.023 14.2 0.0 1.4 8.3 0.0 2.5 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain UPF0079 PF02367.12 EIE81811.1 - 0.031 13.8 0.0 8.7 5.9 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 NTPase_1 PF03266.10 EIE81811.1 - 0.036 13.7 0.8 17 5.0 0.0 3.8 3 1 1 4 4 4 0 NTPase ABC_tran PF00005.22 EIE81811.1 - 0.062 13.5 0.0 12 6.2 0.0 2.7 2 0 0 2 2 2 0 ABC transporter Parvo_NS1 PF01057.12 EIE81811.1 - 0.081 11.7 0.0 1.7 7.4 0.0 2.1 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_30 PF13604.1 EIE81811.1 - 0.089 12.3 0.0 1.3 8.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain WD40 PF00400.27 EIE81812.1 - 4.2e-06 26.4 0.1 1.9e-05 24.3 0.0 2.1 2 0 0 2 2 2 1 WD domain, G-beta repeat Nup160 PF11715.3 EIE81812.1 - 0.053 11.6 0.1 0.07 11.2 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 WD40 PF00400.27 EIE81813.1 - 2.4e-06 27.2 0.1 1.6e-05 24.5 0.0 2.3 2 0 0 2 2 2 1 WD domain, G-beta repeat CH PF00307.26 EIE81814.1 - 3.4e-77 255.4 0.1 1.9e-18 66.4 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EIE81814.1 - 5.3e-14 51.6 0.0 5.5e-05 22.7 0.0 4.3 4 0 0 4 4 4 4 CAMSAP CH domain NAD_Gly3P_dh_N PF01210.18 EIE81815.1 - 0.024 14.3 0.0 0.031 14.0 0.0 1.2 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ThiF PF00899.16 EIE81816.1 - 1.9e-34 118.3 0.2 4.6e-34 117.1 0.0 1.6 2 0 0 2 2 2 1 ThiF family MoeZ_MoeB PF05237.8 EIE81816.1 - 4.1e-10 39.1 3.7 5.5e-05 22.6 0.5 2.4 1 1 1 2 2 2 2 MoeZ/MoeB domain Rhodanese PF00581.15 EIE81816.1 - 8.7e-06 26.0 0.0 1.8e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Tropomyosin_1 PF12718.2 EIE81816.1 - 0.11 12.3 3.8 0.092 12.5 0.6 2.0 2 0 0 2 2 2 0 Tropomyosin like Med10 PF09748.4 EIE81817.1 - 2.8e-18 65.9 0.1 3e-18 65.8 0.1 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex MEDS PF14417.1 EIE81817.1 - 0.05 12.6 0.0 0.054 12.5 0.0 1.0 1 0 0 1 1 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain DUF3993 PF13158.1 EIE81817.1 - 0.12 12.1 0.6 0.15 11.8 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3993) ERM PF00769.14 EIE81818.1 - 0.0049 16.4 1.9 0.006 16.1 1.3 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family HTH_16 PF12645.2 EIE81818.1 - 0.04 13.8 0.0 0.082 12.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain DUF4370 PF14290.1 EIE81818.1 - 0.054 12.9 1.0 0.26 10.7 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4370) DSBA PF01323.15 EIE81818.1 - 0.072 12.6 0.1 0.088 12.3 0.1 1.1 1 0 0 1 1 1 0 DSBA-like thioredoxin domain IncA PF04156.9 EIE81818.1 - 0.11 12.1 0.5 0.17 11.4 0.3 1.4 1 1 0 1 1 1 0 IncA protein Phage_DsbA PF11126.3 EIE81818.1 - 0.78 9.8 4.0 0.51 10.4 0.8 2.1 2 1 0 2 2 2 0 Transcriptional regulator DsbA CTP_transf_1 PF01148.15 EIE81819.1 - 9.4e-09 35.3 4.2 1.4e-08 34.7 2.9 1.3 1 1 0 1 1 1 1 Cytidylyltransferase family AMP-binding PF00501.23 EIE81820.1 - 1.7e-96 323.2 0.0 2e-96 322.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EIE81820.1 - 6.1e-19 68.7 0.2 3.2e-18 66.4 0.0 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain 2-oxoacid_dh PF00198.18 EIE81822.1 - 9.1e-81 270.5 0.3 1.3e-80 270.0 0.2 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EIE81822.1 - 3.2e-17 61.9 1.3 6e-17 61.0 0.9 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme GCV_H PF01597.14 EIE81822.1 - 9.6e-05 22.0 0.5 0.00028 20.5 0.3 1.8 1 0 0 1 1 1 1 Glycine cleavage H-protein RnfC_N PF13375.1 EIE81822.1 - 0.024 14.3 0.2 0.066 12.9 0.2 1.8 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain Biotin_lipoyl_2 PF13533.1 EIE81822.1 - 0.085 12.5 0.7 0.76 9.4 0.1 2.4 1 1 1 2 2 2 0 Biotin-lipoyl like MIP-T3 PF10243.4 EIE81822.1 - 0.11 10.9 16.7 0.16 10.4 11.6 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 RLL PF10036.4 EIE81822.1 - 0.24 10.8 5.2 0.42 9.9 3.6 1.3 1 0 0 1 1 1 0 Putative carnitine deficiency-associated protein RR_TM4-6 PF06459.7 EIE81822.1 - 2.8 7.7 12.0 3.8 7.3 8.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CD20 PF04103.10 EIE81823.1 - 0.033 14.1 0.0 0.036 13.9 0.0 1.0 1 0 0 1 1 1 0 CD20-like family Toxin_37 PF11415.3 EIE81823.1 - 0.25 10.9 5.9 1.9 8.1 0.8 2.2 2 0 0 2 2 2 0 Antifungal peptide termicin DUF2413 PF10310.4 EIE81824.1 - 1.8e-33 116.0 12.4 1.2e-32 113.3 5.5 1.9 1 1 1 2 2 2 2 Protein of unknown function (DUF2413) GNAT_acetyltr_2 PF13718.1 EIE81825.1 - 1.7e-81 272.2 0.0 3.2e-81 271.3 0.0 1.5 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 EIE81825.1 - 5.2e-66 221.6 0.0 1.3e-65 220.3 0.0 1.8 1 0 0 1 1 1 1 Helicase DUF1726 PF08351.6 EIE81825.1 - 3.4e-40 135.6 0.3 1.4e-39 133.6 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 EIE81825.1 - 7.2e-34 115.9 0.1 2.3e-33 114.2 0.1 1.9 1 0 0 1 1 1 1 Possible tRNA binding domain Acetyltransf_7 PF13508.1 EIE81825.1 - 0.0039 17.3 0.0 0.022 14.8 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain DEAD PF00270.24 EIE81825.1 - 0.045 13.2 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 DEAD/DEAH box helicase WD40 PF00400.27 EIE81827.1 - 3.1e-35 118.8 9.3 8.8e-07 28.5 0.0 6.3 6 1 0 6 6 6 5 WD domain, G-beta repeat V_ATPase_I PF01496.14 EIE81827.1 - 0.08 10.7 5.2 0.11 10.3 3.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Adaptin_binding PF10199.4 EIE81827.1 - 0.75 10.0 12.5 1.4 9.2 8.7 1.4 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 TFIIA PF03153.8 EIE81827.1 - 9.9 5.9 24.9 0.59 9.9 13.3 1.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit AT_hook PF02178.14 EIE81828.1 - 0.0025 17.2 72.3 0.014 15.0 1.6 8.0 8 0 0 8 8 8 6 AT hook motif Usp PF00582.21 EIE81828.1 - 0.067 13.3 0.8 0.067 13.3 0.6 2.1 2 0 0 2 2 2 0 Universal stress protein family CD20 PF04103.10 EIE81829.1 - 0.033 14.1 0.0 0.036 13.9 0.0 1.0 1 0 0 1 1 1 0 CD20-like family Toxin_37 PF11415.3 EIE81829.1 - 0.25 10.9 5.9 1.9 8.1 0.8 2.2 2 0 0 2 2 2 0 Antifungal peptide termicin bZIP_2 PF07716.10 EIE81830.1 - 4.8e-09 35.8 13.7 4.8e-09 35.8 9.5 3.2 3 0 0 3 3 3 1 Basic region leucine zipper bZIP_1 PF00170.16 EIE81830.1 - 8.9e-06 25.5 22.9 2.5e-05 24.1 9.0 3.1 1 1 2 3 3 3 1 bZIP transcription factor Mnd1 PF03962.10 EIE81830.1 - 0.0031 17.2 11.9 0.0036 16.9 7.7 1.4 1 1 1 2 2 2 1 Mnd1 family Tropomyosin_1 PF12718.2 EIE81830.1 - 0.27 11.0 15.9 0.27 11.0 10.3 1.6 1 1 0 1 1 1 0 Tropomyosin like DUF3552 PF12072.3 EIE81830.1 - 0.46 9.6 18.2 0.45 9.6 11.7 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) Peptidase_C6 PF00851.13 EIE81830.1 - 0.68 8.4 5.4 0.79 8.2 3.7 1.0 1 0 0 1 1 1 0 Helper component proteinase NEMO PF11577.3 EIE81830.1 - 1.6 8.5 14.7 0.066 12.9 2.8 2.8 1 1 2 3 3 3 0 NF-kappa-B essential modulator NEMO FlxA PF14282.1 EIE81830.1 - 4.2 7.3 10.5 3.4 7.6 6.2 1.7 1 1 0 1 1 1 0 FlxA-like protein Prefoldin_2 PF01920.15 EIE81830.1 - 4.6 7.0 15.5 0.52 10.1 1.1 2.5 3 0 0 3 3 3 0 Prefoldin subunit IncA PF04156.9 EIE81830.1 - 5.5 6.5 20.1 20 4.7 13.9 1.9 1 1 0 1 1 1 0 IncA protein Ax_dynein_light PF10211.4 EIE81830.1 - 6.3 6.5 17.7 0.65 9.8 3.9 2.1 2 0 0 2 2 2 0 Axonemal dynein light chain PspB PF06667.7 EIE81830.1 - 7.4 6.5 7.0 3.4 7.6 1.3 2.7 1 1 2 3 3 3 0 Phage shock protein B HAUS6_N PF14661.1 EIE81830.1 - 8.6 5.6 14.2 2.1 7.6 1.9 2.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus bZIP_Maf PF03131.12 EIE81830.1 - 9.2 6.6 17.6 0.85 9.9 7.0 2.4 1 1 0 2 2 2 0 bZIP Maf transcription factor DUF904 PF06005.7 EIE81830.1 - 9.8 6.5 16.7 46 4.4 6.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF904) RRM_1 PF00076.17 EIE81831.1 - 6.5e-25 86.5 0.0 3.7e-14 52.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PUF PF00806.14 EIE81831.1 - 1.9e-17 61.6 0.1 3.6e-07 29.2 0.0 6.0 5 0 0 5 5 5 3 Pumilio-family RNA binding repeat RRM_5 PF13893.1 EIE81831.1 - 3e-16 59.0 0.2 1.2e-09 37.8 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE81831.1 - 1.4e-15 57.0 0.1 5.1e-09 35.9 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EIE81831.1 - 0.084 12.6 0.0 14 5.5 0.0 2.5 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif CD20 PF04103.10 EIE81832.1 - 0.057 13.3 0.1 0.062 13.2 0.1 1.0 1 0 0 1 1 1 0 CD20-like family zf-Tim10_DDP PF02953.10 EIE81832.1 - 6.9 6.0 8.0 32 3.8 5.5 1.8 1 1 1 2 2 2 0 Tim10/DDP family zinc finger WD40 PF00400.27 EIE81833.1 - 1.5e-22 78.5 0.3 1.1e-06 28.2 0.0 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EIE81833.1 - 0.068 12.6 0.0 0.18 11.3 0.0 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Urocanase PF01175.13 EIE81834.1 - 0.058 11.4 0.0 0.066 11.2 0.0 1.0 1 0 0 1 1 1 0 Urocanase DUF912 PF06024.7 EIE81836.1 - 0.048 13.7 0.2 0.63 10.1 0.2 2.7 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) CotH PF08757.6 EIE81837.1 - 3.9e-43 147.9 0.9 5.8e-43 147.3 0.6 1.1 1 0 0 1 1 1 1 CotH protein Hemerythrin PF01814.18 EIE81837.1 - 0.1 12.7 0.1 0.2 11.8 0.1 1.4 1 0 0 1 1 1 0 Hemerythrin HHE cation binding domain DUF1700 PF08006.6 EIE81838.1 - 0.11 11.7 4.7 0.13 11.5 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) AA_permease_C PF13906.1 EIE81838.1 - 2.7 7.9 12.0 0.41 10.5 5.3 1.8 1 1 1 2 2 2 0 C-terminus of AA_permease Hydrolase_like2 PF13246.1 EIE81839.1 - 5.9e-15 54.9 0.1 1e-13 51.0 0.0 2.4 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase PF00702.21 EIE81839.1 - 2e-13 51.2 0.2 5.1e-11 43.3 0.1 3.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EIE81839.1 - 3.7e-13 50.0 0.4 2.6e-12 47.3 0.3 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EIE81839.1 - 0.00092 18.8 0.4 0.015 14.8 0.0 2.8 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EIE81839.1 - 0.04 14.1 0.0 0.16 12.1 0.0 2.0 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EIE81840.1 - 2e-13 49.9 3.3 3.8e-13 49.0 0.1 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Pneumo_phosprot PF02478.11 EIE81840.1 - 0.025 14.1 2.8 0.052 13.0 2.0 1.5 1 0 0 1 1 1 0 Pneumovirus phosphoprotein SUKH_6 PF14568.1 EIE81840.1 - 0.55 10.7 4.2 0.6 10.5 0.2 2.7 2 2 1 4 4 4 0 SMI1-KNR4 cell-wall HTH_10 PF04967.7 EIE81842.1 - 0.1 12.1 0.1 0.26 10.8 0.0 1.7 1 0 0 1 1 1 0 HTH DNA binding domain Nramp PF01566.13 EIE81843.1 - 1.7e-95 319.8 23.4 1e-81 274.5 9.8 2.0 1 1 1 2 2 2 2 Natural resistance-associated macrophage protein DUF177 PF02620.12 EIE81844.1 - 0.086 12.8 0.1 0.13 12.3 0.0 1.3 1 1 0 1 1 1 0 Uncharacterized ACR, COG1399 DEAD PF00270.24 EIE81845.1 - 6.5e-42 142.8 0.2 6.5e-42 142.8 0.2 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIE81845.1 - 2.3e-23 81.8 0.1 2.3e-23 81.8 0.1 2.3 2 1 1 3 3 3 1 Helicase conserved C-terminal domain UvrD-helicase PF00580.16 EIE81845.1 - 0.019 14.2 5.0 0.37 10.0 0.1 2.2 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain CMS1 PF14617.1 EIE81845.1 - 0.032 13.2 0.1 0.032 13.2 0.1 2.3 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit GRP PF07172.6 EIE81845.1 - 0.53 10.7 6.4 0.96 9.9 4.4 1.4 1 0 0 1 1 1 0 Glycine rich protein family DUF4557 PF15101.1 EIE81845.1 - 2 8.1 12.3 3.7 7.3 8.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Suf PF05843.9 EIE81845.1 - 2.1 8.0 9.9 4.8 6.8 6.8 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) AA_permease_2 PF13520.1 EIE81847.1 - 1.1e-36 126.3 35.4 1.4e-36 126.0 24.5 1.1 1 0 0 1 1 1 1 Amino acid permease Pex24p PF06398.6 EIE81847.1 - 7 5.3 6.7 0.8 8.4 0.3 2.2 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin AA_permease_2 PF13520.1 EIE81848.1 - 6.8e-16 57.8 25.2 7.6e-16 57.6 17.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EIE81848.1 - 2.5e-05 22.8 16.2 2.5e-05 22.8 11.2 1.5 1 1 1 2 2 2 1 Amino acid permease Tim17 PF02466.14 EIE81849.1 - 4.4e-12 46.1 10.7 6.3e-12 45.6 7.4 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Bacteriocin_IIc PF10439.4 EIE81849.1 - 0.38 10.9 11.7 0.32 11.1 1.5 2.2 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Complex1_49kDa PF00346.14 EIE81850.1 - 2.6e-128 426.7 0.0 3.5e-128 426.3 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.14 EIE81850.1 - 0.01 14.6 0.0 0.02 13.6 0.0 1.5 2 0 0 2 2 2 0 Nickel-dependent hydrogenase STE PF02200.11 EIE81851.1 - 5.7e-55 184.1 0.1 1.1e-54 183.2 0.1 1.5 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.21 EIE81851.1 - 0.00015 21.8 3.2 0.00065 19.8 2.2 2.2 1 0 0 1 1 1 1 Zinc finger, C2H2 type Sin3_corepress PF08295.7 EIE81851.1 - 0.024 14.3 0.1 0.057 13.1 0.1 1.6 1 0 0 1 1 1 0 Sin3 family co-repressor zf-C2H2_4 PF13894.1 EIE81851.1 - 0.75 10.2 8.5 0.077 13.3 1.4 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger Pkinase PF00069.20 EIE81852.1 - 8.1e-72 241.4 0.2 8.1e-72 241.4 0.2 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE81852.1 - 2e-52 177.8 0.2 3.5e-52 177.0 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 EIE81852.1 - 7.1e-20 71.1 0.0 2.6e-19 69.3 0.0 2.1 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.1 EIE81852.1 - 3.4e-06 26.2 0.0 1.4e-05 24.2 0.0 1.9 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 EIE81852.1 - 0.00042 20.1 0.0 0.23 11.1 0.0 2.7 2 1 1 3 3 3 2 Phosphotransferase enzyme family Glyco_hydro_47 PF01532.15 EIE81853.1 - 6.8e-101 338.1 0.1 8.8e-101 337.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 4HBT_3 PF13622.1 EIE81854.1 - 0.12 12.1 4.4 0.14 11.8 3.0 1.1 1 0 0 1 1 1 0 Thioesterase-like superfamily DUF605 PF04652.11 EIE81854.1 - 0.16 11.3 13.6 0.21 10.9 9.4 1.1 1 0 0 1 1 1 0 Vta1 like Carboxyl_trans PF01039.17 EIE81855.1 - 3.9e-77 259.6 0.0 4.6e-77 259.4 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain AP_endonuc_2 PF01261.19 EIE81855.1 - 0.091 12.0 0.0 0.21 10.8 0.0 1.5 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel VP9 PF09625.5 EIE81855.1 - 0.17 11.7 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 VP9 protein RRM_1 PF00076.17 EIE81856.1 - 3.5e-27 93.8 0.0 8.2e-14 50.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE81856.1 - 1.4e-19 69.8 0.0 9.5e-10 38.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE81856.1 - 1.3e-05 24.9 0.0 0.026 14.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 EIE81857.1 - 2.4e-29 100.1 11.9 2.9e-10 39.6 0.1 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat PQQ_3 PF13570.1 EIE81857.1 - 0.16 12.3 0.0 7.8 6.9 0.0 2.9 2 0 0 2 2 2 0 PQQ-like domain ABC_membrane PF00664.18 EIE81858.1 - 1.6e-96 322.9 36.1 2.8e-55 187.6 10.9 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EIE81858.1 - 2.8e-71 238.1 0.1 1.2e-35 122.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EIE81858.1 - 6.3e-14 51.7 1.1 1.9e-05 23.9 0.0 4.2 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EIE81858.1 - 4.1e-10 40.1 0.9 0.41 10.5 0.0 5.6 6 0 0 6 6 5 2 AAA domain ABC_ATPase PF09818.4 EIE81858.1 - 1.7e-09 36.7 0.7 0.0014 17.3 0.0 3.3 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_29 PF13555.1 EIE81858.1 - 2.3e-07 30.2 0.3 0.025 14.0 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 EIE81858.1 - 2.6e-07 30.8 3.7 0.011 15.8 0.2 4.3 2 2 0 2 2 2 2 AAA domain DUF258 PF03193.11 EIE81858.1 - 4e-07 29.3 0.0 0.0066 15.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 EIE81858.1 - 7.2e-06 26.8 0.1 0.27 12.0 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 EIE81858.1 - 9.6e-06 25.6 5.1 0.038 13.9 0.3 3.5 2 2 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.1 EIE81858.1 - 2.1e-05 24.2 0.3 0.66 9.5 0.0 4.1 2 2 0 2 2 2 2 AAA domain AAA PF00004.24 EIE81858.1 - 4.4e-05 23.6 5.6 0.74 10.0 1.0 4.3 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EIE81858.1 - 0.00012 21.9 0.5 0.45 10.3 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_10 PF12846.2 EIE81858.1 - 0.00014 21.4 1.1 1.1 8.5 0.0 4.0 4 1 1 5 5 5 2 AAA-like domain SbcCD_C PF13558.1 EIE81858.1 - 0.00022 21.0 6.2 0.19 11.6 0.2 4.0 3 2 0 3 3 2 2 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 EIE81858.1 - 0.00048 20.5 6.9 3.2 8.0 1.2 3.4 3 0 0 3 3 3 1 AAA domain G-alpha PF00503.15 EIE81858.1 - 0.00061 18.5 0.0 0.39 9.3 0.0 2.4 2 0 0 2 2 2 2 G-protein alpha subunit SRP54 PF00448.17 EIE81858.1 - 0.00066 19.1 0.0 0.043 13.2 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_14 PF13173.1 EIE81858.1 - 0.0013 18.6 0.0 1.5 8.7 0.0 4.1 4 0 0 4 4 4 1 AAA domain Zeta_toxin PF06414.7 EIE81858.1 - 0.0013 17.9 0.1 2 7.4 0.0 3.3 3 0 0 3 3 3 1 Zeta toxin RNA_helicase PF00910.17 EIE81858.1 - 0.0017 18.5 0.3 4.3 7.5 0.0 4.0 4 0 0 4 4 3 1 RNA helicase MobB PF03205.9 EIE81858.1 - 0.002 17.8 3.1 1.2 8.8 0.0 3.1 3 1 0 3 3 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 EIE81858.1 - 0.0025 17.5 0.6 0.83 9.4 0.0 3.2 3 0 0 3 3 2 1 Part of AAA domain Rad17 PF03215.10 EIE81858.1 - 0.0039 15.9 0.1 0.063 11.9 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_5 PF07728.9 EIE81858.1 - 0.0055 16.4 0.0 2.8 7.6 0.0 3.4 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EIE81858.1 - 0.0076 15.6 0.9 16 4.8 0.0 3.6 4 0 0 4 4 3 0 AAA domain AAA_18 PF13238.1 EIE81858.1 - 0.014 15.7 0.2 7.2 6.9 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.1 EIE81858.1 - 0.016 15.1 0.1 2.6 7.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain LKAAEAR PF15478.1 EIE81858.1 - 0.026 14.7 0.9 0.052 13.8 0.6 1.4 1 0 0 1 1 1 0 Family of unknown function with LKAAEAR motif NACHT PF05729.7 EIE81858.1 - 0.044 13.4 0.2 11 5.6 0.0 3.3 3 0 0 3 3 2 0 NACHT domain Nuc_deoxyrib_tr PF05014.10 EIE81858.1 - 0.082 12.7 0.3 18 5.2 0.0 2.7 2 0 0 2 2 2 0 Nucleoside 2-deoxyribosyltransferase MMR_HSR1 PF01926.18 EIE81858.1 - 0.24 11.3 3.4 8.4 6.3 0.0 3.6 3 1 0 3 3 2 0 50S ribosome-binding GTPase Ion_trans_2 PF07885.11 EIE81859.1 - 5.2e-12 45.3 0.4 5.5e-12 45.2 0.3 1.0 1 0 0 1 1 1 1 Ion channel SHP PF03579.8 EIE81859.1 - 0.013 14.7 0.1 0.018 14.3 0.1 1.1 1 0 0 1 1 1 0 Small hydrophobic protein BK_channel_a PF03493.13 EIE81860.1 - 8.9e-14 51.2 0.0 9.5e-14 51.1 0.0 1.0 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Mob_synth_C PF06463.8 EIE81862.1 - 1.4e-39 134.6 0.0 1.9e-39 134.2 0.0 1.1 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.16 EIE81862.1 - 5.4e-10 39.6 0.0 1.3e-09 38.4 0.0 1.7 2 0 0 2 2 2 1 Radical SAM superfamily CBM_19 PF03427.8 EIE81862.1 - 0.044 13.5 0.1 0.071 12.8 0.1 1.2 1 0 0 1 1 1 0 Carbohydrate binding domain (family 19) Post_transc_reg PF13797.1 EIE81862.1 - 0.051 13.1 0.0 4.1 7.0 0.0 3.0 3 0 0 3 3 3 0 Post-transcriptional regulator Sod_Fe_C PF02777.13 EIE81862.1 - 0.14 12.0 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 Iron/manganese superoxide dismutases, C-terminal domain RicinB_lectin_2 PF14200.1 EIE81863.1 - 1.3e-15 57.6 0.0 1.1e-10 41.8 0.0 2.0 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 EIE81863.1 - 8.9e-14 51.5 0.0 2e-13 50.4 0.0 1.6 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain MFS_1 PF07690.11 EIE81865.1 - 3.9e-22 78.4 41.9 7.4e-13 47.9 15.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIE81865.1 - 2.2e-06 26.5 29.7 8.2e-05 21.3 13.3 3.4 1 1 1 2 2 2 2 Sugar (and other) transporter ATG22 PF11700.3 EIE81865.1 - 3.9e-05 22.3 1.4 3.9e-05 22.3 0.9 3.1 3 1 0 3 3 3 1 Vacuole effluxer Atg22 like HemY_N PF07219.8 EIE81865.1 - 0.015 14.8 3.3 0.025 14.1 0.3 2.6 2 0 0 2 2 2 0 HemY protein N-terminus NOG1 PF06858.9 EIE81865.1 - 0.12 12.2 1.2 0.26 11.1 0.8 1.5 1 0 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) Orbi_NS3 PF01616.11 EIE81865.1 - 0.18 10.7 0.2 0.41 9.5 0.1 1.5 1 0 0 1 1 1 0 Orbivirus NS3 DUF678 PF05077.7 EIE81866.1 - 0.0015 18.5 0.5 0.0028 17.5 0.2 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF678) RhoGEF PF00621.15 EIE81868.1 - 3e-35 121.7 2.9 3e-35 121.7 2.0 1.8 2 0 0 2 2 2 1 RhoGEF domain Sel1 PF08238.7 EIE81870.1 - 2.4e-127 412.5 57.7 3.6e-12 46.4 0.5 13.2 13 0 0 13 13 13 12 Sel1 repeat TPR_6 PF13174.1 EIE81870.1 - 1.5e-06 28.2 17.3 0.55 10.8 0.1 8.8 10 1 1 11 11 11 2 Tetratricopeptide repeat TPR_17 PF13431.1 EIE81870.1 - 0.0004 20.3 17.8 16 6.0 0.1 9.7 9 1 2 11 11 11 1 Tetratricopeptide repeat TPR_11 PF13414.1 EIE81870.1 - 0.021 14.4 39.3 1.4 8.5 0.5 8.2 3 2 7 10 10 10 0 TPR repeat PPR PF01535.15 EIE81870.1 - 0.27 11.2 3.9 2.4 8.3 0.0 4.1 5 0 0 5 5 5 0 PPR repeat Papo_T_antigen PF02380.10 EIE81870.1 - 1.4 8.8 7.1 4.8 7.1 0.0 4.4 4 0 0 4 4 4 0 T-antigen specific domain NHR2 PF08788.6 EIE81870.1 - 1.6 8.2 4.7 13 5.3 0.0 4.0 4 0 0 4 4 4 0 NHR2 domain like CPSase_L_D2 PF02786.12 EIE81871.1 - 3.9e-76 255.0 0.1 9.3e-76 253.8 0.0 1.7 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 EIE81871.1 - 2e-42 143.7 0.1 8e-42 141.8 0.0 2.1 2 0 0 2 2 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EIE81871.1 - 8.5e-36 122.1 0.0 1.9e-35 121.0 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 EIE81871.1 - 3.5e-16 58.6 0.9 1.5e-15 56.5 0.9 2.0 2 0 0 2 2 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 EIE81871.1 - 5e-14 52.4 0.1 1.1e-13 51.3 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EIE81871.1 - 2e-13 49.7 0.1 3.7e-13 48.9 0.1 1.3 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EIE81871.1 - 1.5e-10 40.8 0.1 3.3e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EIE81871.1 - 2.3e-06 27.0 0.2 4.6e-06 26.0 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 EIE81871.1 - 8.7e-06 25.3 0.1 0.0039 16.8 0.0 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_3 PF13437.1 EIE81871.1 - 8.1e-05 22.9 0.3 0.46 10.8 0.0 3.1 3 0 0 3 3 3 2 HlyD family secretion protein RimK PF08443.6 EIE81871.1 - 9.9e-05 21.8 0.1 0.00029 20.3 0.0 1.7 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 EIE81871.1 - 0.00026 20.9 0.1 0.0008 19.2 0.1 1.9 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.14 EIE81871.1 - 0.00052 19.6 0.1 0.001 18.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DUF3182 PF11379.3 EIE81871.1 - 0.12 11.0 0.0 0.21 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3182) Mso1_Sec1_bdg PF14475.1 EIE81873.1 - 6.5e-07 28.6 0.1 1.7e-06 27.3 0.1 1.7 1 0 0 1 1 1 1 Sec1-binding region of Mso1 APO_RNA-bind PF05634.6 EIE81873.1 - 0.07 12.3 0.1 0.07 12.3 0.0 1.8 2 0 0 2 2 2 0 APO RNA-binding NR_Repeat PF14046.1 EIE81873.1 - 0.88 9.3 0.0 0.88 9.3 0.0 3.2 4 0 0 4 4 4 0 Nuclear receptor repeat UDPGT PF00201.13 EIE81874.1 - 2.4e-26 92.3 0.1 4.6e-24 84.8 0.0 2.5 1 1 0 2 2 2 2 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 EIE81874.1 - 4.3e-07 29.7 0.0 9.4e-07 28.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 EIE81874.1 - 1.8e-05 24.1 0.0 0.0018 17.5 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 1 tRNA-synt_1c PF00749.16 EIE81874.1 - 0.1 11.2 0.0 0.16 10.5 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain dsDNA_bind PF01984.15 EIE81875.1 - 2.8e-07 30.4 4.7 3.4e-07 30.1 2.8 1.4 1 1 0 1 1 1 1 Double-stranded DNA-binding domain EF-1_beta_acid PF10587.4 EIE81875.1 - 0.024 14.7 2.6 0.024 14.7 1.8 2.8 3 0 0 3 3 3 0 Eukaryotic elongation factor 1 beta central acidic region Gryzun PF07919.7 EIE81876.1 - 3.8e-56 190.5 0.8 5.6e-56 189.9 0.5 1.3 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.3 EIE81876.1 - 3.7e-49 167.4 0.1 3.5e-48 164.2 0.1 2.1 1 1 0 1 1 1 1 Foie gras liver health family 1 Gryzun-like PF12742.2 EIE81876.1 - 9.5e-07 28.5 0.0 2.1e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking Apc3 PF12895.2 EIE81876.1 - 0.01 15.9 0.1 0.01 15.9 0.1 3.4 4 1 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EIE81876.1 - 0.038 13.9 0.1 0.16 11.9 0.1 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.1 EIE81876.1 - 0.065 13.0 0.4 1.2 9.1 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TRAPPC10 PF12584.3 EIE81876.1 - 0.11 11.9 0.0 0.27 10.7 0.0 1.6 1 0 0 1 1 1 0 Trafficking protein particle complex subunit 10, TRAPPC10 TPR_1 PF00515.23 EIE81876.1 - 0.16 11.6 2.4 0.24 11.0 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 EIE81876.1 - 0.67 10.0 4.6 0.6 10.1 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat HNH PF01844.18 EIE81877.1 - 9.8e-06 25.3 0.1 9.8e-06 25.3 0.1 2.2 3 0 0 3 3 3 1 HNH endonuclease DZR PF12773.2 EIE81877.1 - 0.0011 18.7 0.3 0.0018 18.0 0.2 1.3 1 0 0 1 1 1 1 Double zinc ribbon HNH_4 PF13395.1 EIE81877.1 - 0.0011 18.4 0.2 0.0024 17.4 0.1 1.5 1 0 0 1 1 1 1 HNH endonuclease VTC PF09359.5 EIE81878.1 - 7.8e-23 80.8 0.4 1.7e-22 79.7 0.1 1.7 2 0 0 2 2 2 1 VTC domain SPX PF03105.14 EIE81878.1 - 5.9e-22 78.7 9.4 1.2e-08 35.0 0.5 3.2 1 1 2 3 3 3 3 SPX domain VTC PF09359.5 EIE81879.1 - 5e-37 127.4 0.2 2.3e-36 125.3 0.0 1.8 2 0 0 2 2 2 1 VTC domain DUF2933 PF11666.3 EIE81879.1 - 0.6 9.6 4.4 1.4 8.5 3.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2933) JAB PF01398.16 EIE81880.1 - 2.2e-35 120.8 0.0 4.7e-35 119.7 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EIE81880.1 - 2e-29 102.0 4.4 3.5e-29 101.1 2.6 1.7 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 EIE81880.1 - 6.4e-08 32.1 0.0 1.1e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Vfa1 PF08432.5 EIE81881.1 - 0.015 15.3 11.3 0.015 15.3 7.8 4.3 1 1 2 3 3 3 0 AAA-ATPase Vps4-associated protein 1 ParBc PF02195.13 EIE81882.1 - 6.4e-10 39.0 0.0 8.6e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 ParB-like nuclease domain YHS PF04945.8 EIE81882.1 - 0.12 12.2 0.1 0.25 11.2 0.1 1.6 1 0 0 1 1 1 0 YHS domain ACOX PF01756.14 EIE81884.1 - 4.2e-24 84.9 0.0 7.5e-24 84.1 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_1 PF00441.19 EIE81884.1 - 0.016 15.3 0.1 0.094 12.8 0.1 2.0 1 1 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain C2 PF00168.25 EIE81885.1 - 1.4e-79 261.9 0.6 4.5e-17 61.6 0.0 6.1 6 0 0 6 6 6 5 C2 domain NT-C2 PF10358.4 EIE81885.1 - 0.02 14.4 0.4 0.32 10.4 0.0 2.9 3 0 0 3 3 3 0 N-terminal C2 in EEIG1 and EHBP1 proteins GPDPase_memb PF10110.4 EIE81885.1 - 0.068 12.5 0.2 0.12 11.7 0.2 1.3 1 0 0 1 1 1 0 Membrane domain of glycerophosphoryl diester phosphodiesterase Pkinase PF00069.20 EIE81887.1 - 6.9e-73 244.9 0.0 1.4e-72 244.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE81887.1 - 4.4e-49 166.8 0.3 9.7e-49 165.7 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.23 EIE81887.1 - 9e-23 80.4 0.0 2.9e-20 72.4 0.0 3.1 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.1 EIE81887.1 - 4.9e-06 25.7 0.0 1e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Kinase-like DSHCT PF08148.7 EIE81887.1 - 0.0052 16.0 0.1 0.012 14.8 0.0 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain APH PF01636.18 EIE81887.1 - 0.046 13.4 0.0 1.2 8.8 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family FAM183 PF14886.1 EIE81887.1 - 7.2 7.1 13.9 14 6.2 3.9 2.9 3 0 0 3 3 3 0 FAM183A and FAM183B related Dzip-like_N PF13815.1 EIE81888.1 - 0.072 12.8 1.4 0.076 12.8 1.0 1.1 1 0 0 1 1 1 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal CAP_GLY PF01302.20 EIE81889.1 - 6.2e-16 57.8 0.1 1.1e-15 57.1 0.1 1.4 1 0 0 1 1 1 1 CAP-Gly domain BTB PF00651.26 EIE81889.1 - 1.6e-13 50.6 0.7 4e-13 49.3 0.5 1.7 1 0 0 1 1 1 1 BTB/POZ domain DUF3342 PF11822.3 EIE81889.1 - 0.02 14.0 0.4 0.058 12.5 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3342) Exo_endo_phos PF03372.18 EIE81891.1 - 1.1e-14 55.0 4.8 2.2e-14 54.0 3.3 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EIE81891.1 - 6.6e-11 41.8 1.8 1.7e-10 40.5 1.2 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase zf-CCHC PF00098.18 EIE81891.1 - 0.0018 18.1 1.9 0.0036 17.1 1.3 1.5 1 0 0 1 1 1 1 Zinc knuckle HECT PF00632.20 EIE81892.1 - 1.7e-91 306.6 0.0 3.7e-91 305.5 0.0 1.6 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF913 PF06025.7 EIE81892.1 - 1.2e-70 238.2 4.1 7.5e-63 212.5 0.9 5.7 6 1 1 7 7 7 2 Domain of Unknown Function (DUF913) DUF908 PF06012.7 EIE81892.1 - 3.2e-19 69.4 0.1 3.2e-19 69.4 0.1 2.7 2 0 0 2 2 2 1 Domain of Unknown Function (DUF908) DUF4414 PF14377.1 EIE81892.1 - 3.5e-18 65.4 3.5 3.5e-18 65.4 2.4 3.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4414) UBA PF00627.26 EIE81892.1 - 3.5e-09 36.2 2.2 1.1e-08 34.6 0.2 2.6 2 0 0 2 2 2 1 UBA/TS-N domain TFIIA PF03153.8 EIE81894.1 - 4.7e-66 224.2 13.4 5.4e-66 224.0 9.3 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Zip PF02535.17 EIE81894.1 - 0.18 10.7 1.5 0.26 10.2 1.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter PP_M1 PF03012.9 EIE81894.1 - 2.3 7.4 10.9 0.11 11.7 0.4 2.4 2 0 0 2 2 2 0 Phosphoprotein CBFD_NFYB_HMF PF00808.18 EIE81896.1 - 3e-30 104.0 0.9 3.9e-30 103.7 0.6 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EIE81896.1 - 2.7e-07 30.5 0.1 4e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.11 EIE81896.1 - 0.00079 19.1 0.0 0.00091 18.9 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.8 EIE81896.1 - 0.0095 15.6 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated PurA PF04845.8 EIE81896.1 - 0.013 14.6 0.1 0.029 13.5 0.1 1.5 1 1 1 2 2 2 0 PurA ssDNA and RNA-binding protein TFIID_20kDa PF03847.8 EIE81896.1 - 0.073 13.3 0.1 0.26 11.5 0.0 1.8 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A CENP-X PF09415.5 EIE81896.1 - 0.099 12.4 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 CENP-S associating Centromere protein X DUF1180 PF06679.7 EIE81897.1 - 0.28 11.0 0.0 0.28 11.0 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1180) TMEM51 PF15345.1 EIE81897.1 - 2.9 7.5 9.0 4.8 6.8 6.2 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 Ycf1 PF05758.7 EIE81897.1 - 5.4 4.5 17.0 6.1 4.4 11.8 1.1 1 0 0 1 1 1 0 Ycf1 DUF2040 PF09745.4 EIE81898.1 - 0.02 14.7 0.2 0.044 13.6 0.0 1.6 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 55 (DUF2040) Na_H_Exchanger PF00999.16 EIE81900.1 - 2.6e-50 171.0 31.4 3.3e-50 170.7 21.8 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Pyr_redox_2 PF07992.9 EIE81901.1 - 3.6e-16 59.6 0.1 4.6e-16 59.2 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EIE81901.1 - 1.7e-13 50.7 0.1 4e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EIE81901.1 - 4.6e-06 26.8 0.0 9.6e-05 22.5 0.0 2.0 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 EIE81901.1 - 0.0088 16.2 0.2 0.052 13.7 0.0 2.2 2 1 0 2 2 2 1 Putative NAD(P)-binding K_oxygenase PF13434.1 EIE81901.1 - 0.031 13.2 0.1 1.2 7.9 0.0 2.1 1 1 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.17 EIE81901.1 - 0.043 12.6 0.1 6.9 5.4 0.0 3.0 3 0 0 3 3 3 0 Glucose inhibited division protein A YvrJ PF12841.2 EIE81902.1 - 0.12 11.6 1.8 2.9 7.2 0.3 2.6 2 1 0 2 2 2 0 YvrJ protein family Sel1 PF08238.7 EIE81905.1 - 2.2e-40 136.1 24.6 1.8e-09 37.9 0.1 8.1 8 0 0 8 8 8 7 Sel1 repeat TPR_6 PF13174.1 EIE81905.1 - 0.08 13.4 0.3 0.08 13.4 0.2 5.1 5 2 1 6 6 6 0 Tetratricopeptide repeat MIT PF04212.13 EIE81905.1 - 0.18 11.6 11.0 3.9 7.4 0.0 5.0 4 1 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_11 PF13414.1 EIE81905.1 - 2 8.1 13.7 2.7 7.7 2.5 4.5 3 1 1 4 4 4 0 TPR repeat TPR_1 PF00515.23 EIE81905.1 - 3.4 7.4 14.0 5.3 6.8 0.1 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat GATA PF00320.22 EIE81906.1 - 0.037 13.3 0.9 0.037 13.3 0.6 2.6 3 0 0 3 3 3 0 GATA zinc finger zf-UBP PF02148.14 EIE81906.1 - 2.1 8.4 7.3 17 5.5 5.0 2.3 1 1 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein RabGAP-TBC PF00566.13 EIE81907.1 - 1.6e-35 122.5 0.1 1.2e-18 67.3 0.0 2.7 1 1 1 2 2 2 2 Rab-GTPase-TBC domain CENP-F_leu_zip PF10473.4 EIE81907.1 - 0.0038 17.0 18.3 0.0038 17.0 12.7 4.0 4 0 0 4 4 4 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2205 PF10224.4 EIE81907.1 - 8.9 5.9 13.9 0.33 10.5 3.5 3.2 3 1 0 3 3 3 0 Predicted coiled-coil protein (DUF2205) Velvet PF11754.3 EIE81908.1 - 1.2e-44 152.4 0.2 4e-23 82.0 0.1 2.1 1 1 1 2 2 2 2 Velvet factor tRNA-synt_2b PF00587.20 EIE81909.1 - 3.1e-41 140.8 0.1 6e-41 139.8 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EIE81909.1 - 8.9e-18 64.0 0.1 1.9e-17 63.0 0.1 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.9 EIE81909.1 - 1.8e-14 53.3 0.0 3.8e-14 52.2 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.16 EIE81909.1 - 3.8e-13 49.0 0.0 1.7e-12 46.9 0.0 2.2 2 0 0 2 2 2 1 TGS domain SRF-TF PF00319.13 EIE81910.1 - 1.5e-22 78.5 0.1 2.2e-22 78.0 0.0 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) SAP PF02037.22 EIE81911.1 - 1.4e-10 40.3 0.2 2.3e-10 39.6 0.1 1.3 1 0 0 1 1 1 1 SAP domain FAD_binding_3 PF01494.14 EIE81912.1 - 1.2e-11 44.2 0.1 1.3e-10 40.8 0.1 2.0 1 1 0 1 1 1 1 FAD binding domain SE PF08491.5 EIE81912.1 - 0.00027 19.8 0.0 0.0058 15.5 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase HBS1_N PF08938.5 EIE81912.1 - 0.17 12.0 0.5 3.2 7.9 0.1 2.7 2 1 0 2 2 2 0 HBS1 N-terminus Myb_DNA-binding PF00249.26 EIE81913.1 - 4.9e-15 55.3 1.8 1.2e-14 54.1 1.3 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EIE81913.1 - 1.4e-11 44.3 0.9 1.4e-11 44.3 0.7 2.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain Calcipressin PF04847.7 EIE81916.1 - 4.9e-20 71.8 0.2 5.7e-20 71.6 0.2 1.1 1 0 0 1 1 1 1 Calcipressin Tenui_PVC2 PF06656.6 EIE81916.1 - 0.16 9.7 0.0 0.19 9.4 0.0 1.1 1 0 0 1 1 1 0 Tenuivirus PVC2 protein MAS20 PF02064.10 EIE81917.1 - 1e-23 83.5 0.7 6.8e-23 80.8 0.5 1.9 1 1 0 1 1 1 1 MAS20 protein import receptor DUF2962 PF11176.3 EIE81917.1 - 0.029 13.9 1.7 0.043 13.3 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2962) TPR_1 PF00515.23 EIE81917.1 - 0.05 13.2 0.2 0.15 11.7 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF4652 PF15525.1 EIE81917.1 - 0.2 11.0 1.5 0.27 10.6 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4652) DUF3292 PF11696.3 EIE81918.1 - 0.57 7.9 4.9 0.6 7.9 3.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) DUF1752 PF08550.5 EIE81919.1 - 0.0083 15.6 1.9 0.02 14.4 1.3 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) LAM_C PF12544.3 EIE81919.1 - 0.095 12.7 0.2 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 Lysine-2,3-aminomutase Got1 PF04178.7 EIE81920.1 - 3.8e-20 72.1 12.3 4.1e-20 72.0 8.5 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family DUF973 PF06157.6 EIE81920.1 - 0.87 8.5 12.1 2.2 7.1 8.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF973) GAS2 PF02187.12 EIE81921.1 - 3.4e-08 33.1 0.1 9.4e-08 31.7 0.0 1.8 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Sec7 PF01369.15 EIE81922.1 - 1.1e-08 35.0 0.1 2.3e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Sec7 domain Phage_terminase PF10668.4 EIE81922.1 - 0.075 12.8 0.2 0.35 10.6 0.0 2.2 2 0 0 2 2 2 0 Phage terminase small subunit NPL4 PF05021.10 EIE81923.1 - 4.2e-113 377.5 0.0 5.3e-113 377.2 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 EIE81923.1 - 1.4e-39 135.0 2.7 3.1e-30 104.7 0.3 3.0 1 1 2 3 3 3 2 NPL4 family, putative zinc binding region UN_NPL4 PF11543.3 EIE81923.1 - 2.7e-09 37.1 0.0 6.5e-09 35.9 0.0 1.7 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 STAT1_TAZ2bind PF12162.3 EIE81923.1 - 0.008 15.5 0.0 0.017 14.5 0.0 1.6 1 0 0 1 1 1 1 STAT1 TAZ2 binding domain zf-RanBP PF00641.13 EIE81923.1 - 0.02 13.9 3.4 0.04 13.0 2.3 1.5 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others Lipoprotein_9 PF03180.9 EIE81923.1 - 0.061 12.2 0.3 0.4 9.5 0.0 2.3 3 0 0 3 3 3 0 NLPA lipoprotein DZR PF12773.2 EIE81923.1 - 1.6 8.6 6.6 0.13 12.1 0.6 2.1 2 0 0 2 2 2 0 Double zinc ribbon DUF1887 PF09002.6 EIE81924.1 - 0.073 11.4 0.2 0.079 11.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1887) adh_short PF00106.20 EIE81925.1 - 0.00074 19.4 0.0 0.00095 19.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Not1 PF04054.10 EIE81926.1 - 4.2e-111 371.4 0.5 4.2e-111 371.4 0.4 2.4 2 1 0 2 2 2 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 EIE81926.1 - 1.6e-36 125.2 0.6 1.6e-36 125.2 0.4 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) Med15 PF09606.5 EIE81926.1 - 0.0041 15.3 36.7 0.0064 14.7 25.4 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Spt20 PF12090.3 EIE81926.1 - 0.4 10.0 14.2 0.15 11.4 5.5 2.5 2 0 0 2 2 2 0 Spt20 family BAF1_ABF1 PF04684.8 EIE81926.1 - 1.9 7.2 19.0 3.2 6.4 13.2 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Suf PF05843.9 EIE81926.1 - 9.4 5.8 17.0 0.53 9.9 7.0 2.3 3 0 0 3 3 3 0 Suppressor of forked protein (Suf) UPF0020 PF01170.13 EIE81927.1 - 5.9e-27 94.4 0.0 8.9e-27 93.8 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 EIE81927.1 - 4e-11 42.9 0.0 5.9e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EIE81927.1 - 1.5e-09 37.5 0.0 2.1e-08 33.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_4 PF02390.12 EIE81927.1 - 2.2e-09 36.6 0.0 4.4e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.1 EIE81927.1 - 7e-08 32.2 0.0 1.5e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIE81927.1 - 2.8e-07 29.8 0.0 4.4e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family THUMP PF02926.12 EIE81927.1 - 0.0003 20.6 0.0 0.0005 19.9 0.0 1.4 1 0 0 1 1 1 1 THUMP domain Methyltransf_11 PF08241.7 EIE81927.1 - 0.00031 21.1 0.0 0.00091 19.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIE81927.1 - 0.0039 17.7 0.0 0.0082 16.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EIE81927.1 - 0.0065 15.5 0.0 0.012 14.6 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.1 EIE81927.1 - 0.011 16.1 0.0 0.02 15.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain N6_Mtase PF02384.11 EIE81927.1 - 0.015 14.4 0.0 0.05 12.6 0.0 1.8 1 1 0 1 1 1 0 N-6 DNA Methylase N6_N4_Mtase PF01555.13 EIE81927.1 - 0.097 12.1 0.7 4.1 6.8 0.1 2.4 2 1 0 2 2 2 0 DNA methylase HABP4_PAI-RBP1 PF04774.10 EIE81928.1 - 0.003 18.0 0.0 0.0036 17.7 0.0 1.1 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family ATP-synt_D PF01813.12 EIE81929.1 - 0.0093 15.5 0.1 0.0093 15.5 0.1 1.0 1 0 0 1 1 1 1 ATP synthase subunit D PhaP_Bmeg PF09602.5 EIE81929.1 - 0.077 12.8 0.1 0.085 12.6 0.1 1.1 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) KNOX2 PF03791.8 EIE81929.1 - 0.13 11.5 0.2 0.18 11.0 0.1 1.3 1 0 0 1 1 1 0 KNOX2 domain FUSC_2 PF13515.1 EIE81930.1 - 1.1e-19 70.6 6.8 1.1e-19 70.6 4.7 3.0 2 2 1 3 3 3 1 Fusaric acid resistance protein-like FUSC PF04632.7 EIE81930.1 - 4.8e-13 48.4 9.5 5.1e-10 38.4 3.8 2.5 2 1 0 2 2 2 2 Fusaric acid resistance protein family ALMT PF11744.3 EIE81930.1 - 1.4e-09 37.1 13.2 4.5e-09 35.4 1.0 2.6 2 1 0 2 2 2 2 Aluminium activated malate transporter DUF2421 PF10334.4 EIE81930.1 - 1.5e-09 37.8 1.5 8.7e-09 35.3 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) DUF939 PF06081.6 EIE81930.1 - 0.029 14.2 7.4 0.015 15.1 1.7 2.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF939) Aldedh PF00171.17 EIE81931.1 - 1e-17 63.6 5.6 2.3e-14 52.6 1.3 2.4 1 1 0 2 2 2 2 Aldehyde dehydrogenase family Cu-oxidase_3 PF07732.10 EIE81932.1 - 2.5e-31 107.8 0.6 6.4e-31 106.5 0.4 1.7 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase PF00394.17 EIE81932.1 - 4e-25 88.5 0.2 1.1e-24 87.0 0.0 1.8 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EIE81932.1 - 5.5e-22 77.7 8.2 3.1e-20 72.0 0.4 3.2 2 1 0 2 2 2 2 Multicopper oxidase Cupredoxin_1 PF13473.1 EIE81932.1 - 0.026 14.3 0.0 11 5.9 0.0 2.5 2 0 0 2 2 2 0 Cupredoxin-like domain Bap31 PF05529.7 EIE81933.1 - 1.6e-53 180.9 8.3 2e-53 180.7 5.7 1.1 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like Phage_GP20 PF06810.6 EIE81933.1 - 0.0026 17.2 12.8 0.0053 16.2 8.8 1.5 1 0 0 1 1 1 1 Phage minor structural protein GP20 DUF1843 PF08898.5 EIE81933.1 - 0.069 13.1 0.4 0.069 13.1 0.3 2.3 3 1 0 3 3 3 0 Domain of unknown function (DUF1843) HALZ PF02183.13 EIE81933.1 - 0.071 12.8 8.0 0.056 13.1 1.7 2.6 1 1 1 2 2 2 0 Homeobox associated leucine zipper NPV_P10 PF05531.7 EIE81933.1 - 0.21 11.8 3.2 0.28 11.4 1.8 1.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF342 PF03961.8 EIE81933.1 - 0.77 8.1 7.4 1 7.7 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DivIC PF04977.10 EIE81933.1 - 1.7 8.2 17.1 0.28 10.6 3.8 3.3 2 1 1 3 3 3 0 Septum formation initiator DUF724 PF05266.9 EIE81933.1 - 3.9 7.0 11.2 2 7.9 6.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF724) TPR_MLP1_2 PF07926.7 EIE81933.1 - 5.6 6.7 18.4 5.7 6.6 10.3 2.4 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Phage_Gp23 PF10669.4 EIE81933.1 - 9.8 6.3 9.6 8.6 6.5 2.1 2.9 2 1 1 3 3 3 0 Protein gp23 (Bacteriophage A118) Mod_r PF07200.8 EIE81934.1 - 0.0015 18.4 1.7 0.0017 18.3 1.2 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Pkinase PF00069.20 EIE81935.1 - 3.4e-38 131.2 0.1 3.1e-21 75.6 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIE81935.1 - 3.2e-15 55.9 0.0 1e-08 34.5 0.0 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase PACT_coil_coil PF10495.4 EIE81935.1 - 0.049 13.5 0.0 0.17 11.8 0.0 1.8 2 0 0 2 2 2 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein zf-UBR PF02207.15 EIE81936.1 - 3.9e-16 58.5 7.7 3.9e-16 58.5 5.3 3.4 3 1 1 4 4 4 1 Putative zinc finger in N-recognin (UBR box) Pkinase PF00069.20 EIE81937.1 - 4.4e-22 78.4 0.0 8e-22 77.6 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE81937.1 - 0.0007 18.7 0.0 0.00098 18.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF4407 PF14362.1 EIE81938.1 - 4.7 6.0 9.9 0.094 11.6 1.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Ribosomal_S2 PF00318.15 EIE81939.1 - 1.7e-53 181.0 0.0 1.7e-29 102.5 0.0 2.2 2 0 0 2 2 2 2 Ribosomal protein S2 zf-H2C2_2 PF13465.1 EIE81943.1 - 1.2e-24 85.3 24.2 5.3e-08 32.7 0.2 5.6 6 0 0 6 6 6 3 Zinc-finger double domain zf-C2H2 PF00096.21 EIE81943.1 - 4.5e-22 76.9 30.4 5.3e-06 26.4 0.9 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIE81943.1 - 5.4e-12 45.1 34.8 0.00089 19.4 0.7 4.8 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EIE81943.1 - 0.0002 21.4 11.2 2.2 8.5 0.1 4.6 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EIE81943.1 - 0.00097 18.9 16.4 0.32 10.9 0.3 4.4 4 0 0 4 4 4 2 C2H2-type zinc finger zf-met PF12874.2 EIE81943.1 - 0.0042 17.2 10.5 3.2 8.0 0.1 4.8 4 1 0 4 4 4 2 Zinc-finger of C2H2 type zf-TRAF PF02176.13 EIE81943.1 - 0.032 14.6 16.8 0.29 11.5 2.2 3.3 2 1 1 3 3 3 0 TRAF-type zinc finger Ogr_Delta PF04606.7 EIE81943.1 - 0.073 12.7 9.7 2.7 7.7 0.3 3.8 1 1 3 4 4 4 0 Ogr/Delta-like zinc finger TRH PF05438.7 EIE81943.1 - 0.21 10.9 5.4 0.73 9.1 3.7 1.8 1 1 0 1 1 1 0 Thyrotropin-releasing hormone (TRH) zf-CGNR PF11706.3 EIE81943.1 - 7.2 6.2 14.4 2.8 7.5 2.3 3.8 3 1 0 3 3 3 0 CGNR zinc finger tRNA-synt_1g PF09334.6 EIE81944.1 - 3e-145 483.7 0.1 4.2e-145 483.2 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EIE81944.1 - 7.6e-09 34.1 0.3 4.6e-06 24.9 0.0 3.1 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) Med27 PF11571.3 EIE81944.1 - 0.3 11.2 3.6 8.6 6.5 0.1 3.6 2 1 1 3 3 3 0 Mediator complex subunit 27 L51_S25_CI-B8 PF05047.11 EIE81945.1 - 8.6e-11 41.4 0.0 1.2e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain NGP1NT PF08153.7 EIE81946.1 - 2.6e-51 172.9 0.2 2.6e-51 172.9 0.2 2.1 2 0 0 2 2 2 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 EIE81946.1 - 7.6e-19 67.7 0.4 2.9e-14 52.9 0.0 3.1 3 1 0 3 3 3 2 50S ribosome-binding GTPase FeoB_N PF02421.13 EIE81946.1 - 0.00039 19.7 0.1 0.0029 16.9 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B Arf PF00025.16 EIE81946.1 - 0.00071 18.8 0.1 0.2 10.8 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family GTP_EFTU PF00009.22 EIE81946.1 - 0.0011 18.4 0.0 0.14 11.5 0.0 3.3 2 1 0 3 3 3 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EIE81946.1 - 0.0066 15.6 0.0 0.015 14.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EIE81946.1 - 0.21 11.3 18.5 0.34 10.7 0.1 5.3 3 2 0 3 3 3 0 Dynamin family CENP-T PF15511.1 EIE81946.1 - 2.9 7.0 19.5 5.2 6.2 13.5 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T IBV_3C PF03620.8 EIE81947.1 - 0.0048 16.7 0.0 0.0087 15.9 0.0 1.4 1 0 0 1 1 1 1 IBV 3C protein DUF4207 PF13904.1 EIE81947.1 - 0.84 8.9 3.8 1.4 8.2 2.6 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4207) Pkinase PF00069.20 EIE81948.1 - 2.2e-43 148.2 0.0 4.3e-43 147.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE81948.1 - 4.5e-29 101.2 0.0 7.8e-29 100.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 EIE81948.1 - 7e-24 83.7 0.2 1.7e-23 82.5 0.2 1.7 1 0 0 1 1 1 1 Ras-binding domain of Byr2 RA PF00788.18 EIE81948.1 - 2.2e-09 37.6 0.0 4.5e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Kinase-like PF14531.1 EIE81948.1 - 2.2e-05 23.5 0.0 0.001 18.0 0.0 2.2 2 0 0 2 2 2 1 Kinase-like SAM_1 PF00536.25 EIE81948.1 - 0.0009 19.3 0.0 0.0022 18.1 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EIE81948.1 - 0.0023 17.7 0.0 0.0056 16.4 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF2870 PF11069.3 EIE81948.1 - 0.06 13.3 0.1 0.52 10.3 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2870) APH PF01636.18 EIE81948.1 - 0.17 11.5 0.1 2 8.0 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Sec1 PF00995.18 EIE81949.1 - 4.9e-82 276.3 0.1 5.4e-82 276.2 0.1 1.0 1 0 0 1 1 1 1 Sec1 family Not3 PF04065.10 EIE81949.1 - 0.072 12.3 0.6 0.86 8.8 0.2 2.4 2 1 0 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component MAP65_ASE1 PF03999.7 EIE81950.1 - 5.3e-17 61.6 34.3 9.2e-15 54.2 23.9 2.5 1 1 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) MMS1_N PF10433.4 EIE81951.1 - 8.5e-34 116.5 3.0 1.4e-33 115.8 2.1 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 EIE81951.1 - 5.7e-32 111.0 0.2 1e-27 97.0 0.1 2.7 2 0 0 2 2 2 2 CPSF A subunit region Recep_L_domain PF01030.19 EIE81952.1 - 0.0004 20.3 2.7 0.47 10.4 0.0 4.0 2 2 0 2 2 2 2 Receptor L domain DUF3971 PF13116.1 EIE81952.1 - 0.032 13.6 1.0 0.52 9.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function SPX PF03105.14 EIE81953.1 - 5.9e-41 141.0 7.4 1e-40 140.2 5.2 1.4 1 1 0 1 1 1 1 SPX domain Na_sulph_symp PF00939.14 EIE81953.1 - 5.6e-31 107.9 29.9 7.7e-31 107.4 20.7 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 EIE81953.1 - 5.6e-14 51.4 37.7 1.1e-10 40.7 15.2 2.5 1 1 2 3 3 3 2 Citrate transporter zf-C2H2 PF00096.21 EIE81955.1 - 0.0043 17.2 3.0 0.0077 16.5 2.1 1.4 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIE81955.1 - 0.028 14.7 1.1 0.062 13.6 0.5 1.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EIE81955.1 - 0.29 11.0 1.5 0.53 10.2 1.0 1.3 1 0 0 1 1 1 0 C2H2-type zinc finger ADK PF00406.17 EIE81956.1 - 4e-06 26.7 0.0 4.5e-06 26.6 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase TnpV PF14198.1 EIE81958.1 - 0.11 12.3 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Transposon-encoded protein TnpV Perilipin PF03036.11 EIE81959.1 - 2.6e-05 23.2 9.0 8.2e-05 21.6 0.0 2.9 1 1 1 2 2 2 1 Perilipin family Seadorna_VP6 PF07407.6 EIE81959.1 - 0.15 10.7 3.1 0.23 10.1 2.2 1.2 1 0 0 1 1 1 0 Seadornavirus VP6 protein zf-CpG_bind_C PF12269.3 EIE81959.1 - 0.48 9.8 5.8 1 8.7 4.0 1.5 1 0 0 1 1 1 0 CpG binding protein zinc finger C terminal domain Rtt102p PF09510.5 EIE81959.1 - 1.6 8.6 9.9 6.7 6.7 2.3 2.3 2 0 0 2 2 2 0 Rtt102p-like transcription regulator protein zf-C2H2 PF00096.21 EIE81960.1 - 0.00081 19.5 0.7 0.00081 19.5 0.5 4.5 5 1 0 5 5 5 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIE81960.1 - 0.014 15.7 0.5 0.014 15.7 0.3 4.7 6 0 0 6 6 6 0 C2H2-type zinc finger DUF4187 PF13821.1 EIE81960.1 - 0.65 9.6 7.7 0.76 9.4 3.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) DUF4283 PF14111.1 EIE81961.1 - 0.026 13.5 0.0 0.036 13.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4283) PS_Dcarbxylase PF02666.10 EIE81962.1 - 2e-54 184.0 0.0 5.4e-54 182.5 0.0 1.7 2 0 0 2 2 2 1 Phosphatidylserine decarboxylase Bap31 PF05529.7 EIE81963.1 - 1.2e-39 135.7 0.2 1.3e-39 135.6 0.2 1.0 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like WD40 PF00400.27 EIE81964.1 - 3.3e-69 226.5 30.6 1e-11 44.2 0.4 7.9 7 1 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.2 EIE81964.1 - 5.7e-15 54.7 0.0 1.4e-14 53.5 0.0 1.7 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 EIE81964.1 - 1.6e-14 52.9 15.2 0.0049 15.0 0.1 6.2 2 2 2 5 5 5 5 Nucleoporin Nup120/160 F-box PF00646.28 EIE81964.1 - 8.3e-09 34.8 0.0 1.7e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 F-box domain Nucleoporin_N PF08801.6 EIE81964.1 - 8.2e-06 24.8 1.8 0.06 12.0 0.0 4.1 2 1 1 4 4 4 1 Nup133 N terminal like BBS2_Mid PF14783.1 EIE81964.1 - 0.00026 20.7 0.0 4.6 7.0 0.0 4.0 3 1 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region PRANC PF09372.5 EIE81964.1 - 0.021 14.7 0.0 0.041 13.8 0.0 1.5 1 0 0 1 1 1 0 PRANC domain bZIP_2 PF07716.10 EIE81965.1 - 3.7e-10 39.4 9.8 5.9e-10 38.8 6.8 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 EIE81965.1 - 0.0041 17.0 9.9 0.0068 16.3 6.8 1.3 1 0 0 1 1 1 1 bZIP transcription factor DUF2762 PF10960.3 EIE81965.1 - 0.19 11.4 1.8 0.34 10.6 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2762) Calcipressin PF04847.7 EIE81965.1 - 0.49 9.9 5.3 0.97 8.9 3.7 1.6 1 1 0 1 1 1 0 Calcipressin Ribosomal_L32p PF01783.18 EIE81965.1 - 4.2 7.6 6.2 9.5 6.4 4.2 1.7 1 1 0 1 1 1 0 Ribosomal L32p protein family Pkinase PF00069.20 EIE81966.1 - 6.3e-61 205.7 0.0 8e-61 205.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE81966.1 - 3.6e-31 108.1 0.0 4.6e-31 107.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE81966.1 - 0.00094 18.2 0.0 0.0025 16.8 0.0 1.7 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 EIE81966.1 - 0.018 14.8 0.0 0.67 9.6 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 EIE81966.1 - 0.1 12.1 0.4 0.35 10.4 0.0 1.9 2 1 0 2 2 2 0 Choline/ethanolamine kinase Kdo PF06293.9 EIE81966.1 - 0.11 11.4 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Mon1 PF03164.9 EIE81968.1 - 2.6e-93 312.9 1.2 3.5e-93 312.4 0.9 1.1 1 0 0 1 1 1 1 Trafficking protein Mon1 SBDS_C PF09377.5 EIE81969.1 - 2.2e-30 104.9 0.8 2.6e-30 104.7 0.6 1.1 1 0 0 1 1 1 1 SBDS protein C-terminal domain DUF3734 PF12536.3 EIE81969.1 - 0.037 14.1 0.3 0.076 13.1 0.0 1.6 2 0 0 2 2 2 0 Patatin phospholipase HTH_22 PF13309.1 EIE81969.1 - 0.054 13.2 1.2 0.057 13.1 0.1 1.6 2 0 0 2 2 2 0 HTH domain UCH PF00443.24 EIE81970.1 - 6.8e-53 179.4 0.0 1.1e-52 178.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EIE81970.1 - 3.9e-11 42.9 0.0 2.1e-10 40.5 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Zn_protease PF05618.6 EIE81971.1 - 0.046 13.4 0.6 0.058 13.0 0.4 1.1 1 0 0 1 1 1 0 Putative ATP-dependant zinc protease SseC PF04888.7 EIE81971.1 - 0.22 10.8 1.7 0.29 10.4 1.1 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Ribosomal_S18 PF01084.15 EIE81971.1 - 2.4 8.0 7.3 7.5 6.5 4.4 2.3 2 1 0 2 2 2 0 Ribosomal protein S18 MFS_1 PF07690.11 EIE81972.1 - 3.2e-16 59.0 3.6 3.4e-16 58.9 2.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIE81972.1 - 1.8e-07 30.0 0.6 2.1e-07 29.8 0.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter DUF308 PF03729.8 EIE81972.1 - 7.4 6.6 11.2 4.3 7.3 0.3 2.4 2 1 0 2 2 2 0 Short repeat of unknown function (DUF308) RRM_1 PF00076.17 EIE81973.1 - 2.4e-14 52.7 0.0 4.7e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SH3_9 PF14604.1 EIE81973.1 - 6e-11 41.7 0.1 1.1e-10 40.9 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EIE81973.1 - 7.1e-10 38.1 0.0 1.2e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 SH3 domain RRM_6 PF14259.1 EIE81973.1 - 2e-07 30.8 0.0 4.1e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) SH3_2 PF07653.12 EIE81973.1 - 2.7e-07 29.9 0.0 4.8e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain FoP_duplication PF13865.1 EIE81973.1 - 2.6e-06 27.7 0.4 2.6e-06 27.7 0.3 2.8 3 0 0 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 RRM_5 PF13893.1 EIE81973.1 - 2.3e-05 24.1 0.0 6.1e-05 22.7 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PAT1 PF09770.4 EIE81973.1 - 0.074 11.2 40.2 0.1 10.7 27.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ribosomal_L9_N PF01281.14 EIE81974.1 - 1.8e-13 49.5 0.0 3.6e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain Ribosomal_L9_C PF03948.9 EIE81974.1 - 1.6e-12 47.2 0.9 1.6e-12 47.2 0.6 1.6 2 0 0 2 2 2 1 Ribosomal protein L9, C-terminal domain PqqD PF05402.7 EIE81974.1 - 0.0018 18.2 0.2 0.056 13.4 0.0 2.7 3 0 0 3 3 3 1 Coenzyme PQQ synthesis protein D (PqqD) EMP24_GP25L PF01105.19 EIE81974.1 - 0.036 13.7 0.0 0.073 12.7 0.0 1.5 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF3782 PF12644.2 EIE81974.1 - 0.56 10.0 5.9 15 5.4 3.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3782) CK_II_beta PF01214.13 EIE81976.1 - 1.6e-77 259.2 0.1 1.9e-77 258.9 0.1 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Glyco_hydro_100 PF12899.2 EIE81976.1 - 0.043 12.2 0.0 0.06 11.7 0.0 1.1 1 0 0 1 1 1 0 Alkaline and neutral invertase MAPKK1_Int PF08923.5 EIE81977.1 - 6.7e-29 99.9 0.2 7.8e-29 99.7 0.2 1.0 1 0 0 1 1 1 1 Mitogen-activated protein kinase kinase 1 interacting Ricin_B_lectin PF00652.17 EIE81978.1 - 8.2e-05 22.6 0.0 0.2 11.6 0.0 2.6 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 EIE81978.1 - 0.013 15.9 0.0 0.81 10.0 0.0 2.5 1 1 1 2 2 2 0 Ricin-type beta-trefoil lectin domain-like Vint PF14623.1 EIE81978.1 - 0.089 12.2 0.1 0.27 10.6 0.0 1.8 2 1 1 3 3 3 0 Hint-domain Adap_comp_sub PF00928.16 EIE81979.1 - 0.0038 16.3 0.0 0.0042 16.2 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family YbbR PF07949.7 EIE81979.1 - 0.087 12.9 0.1 0.2 11.7 0.1 1.6 1 1 0 1 1 1 0 YbbR-like protein CAF1 PF04857.15 EIE81980.1 - 1.5e-40 139.1 0.1 8.8e-39 133.3 0.1 2.4 1 1 0 1 1 1 1 CAF1 family ribonuclease TFIIA PF03153.8 EIE81980.1 - 3.2e-05 24.0 3.1 3.2e-05 24.0 2.2 1.5 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit RNA_pol_3_Rpc31 PF11705.3 EIE81980.1 - 0.029 14.3 23.9 0.086 12.7 16.6 1.7 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 BTV_NS2 PF04514.7 EIE81980.1 - 0.045 12.6 7.5 0.093 11.5 5.2 1.4 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 RXT2_N PF08595.6 EIE81980.1 - 0.054 13.2 5.6 0.19 11.4 3.9 2.0 1 0 0 1 1 1 0 RXT2-like, N-terminal CDC45 PF02724.9 EIE81980.1 - 0.24 9.4 11.3 0.46 8.4 7.8 1.4 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.8 EIE81980.1 - 0.4 8.4 21.4 0.61 7.7 14.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi TRAP_alpha PF03896.11 EIE81980.1 - 0.86 8.5 9.6 1.8 7.4 6.7 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Nop14 PF04147.7 EIE81980.1 - 0.97 7.2 16.8 1.9 6.3 11.6 1.4 1 0 0 1 1 1 0 Nop14-like family CENP-B_dimeris PF09026.5 EIE81980.1 - 1.1 9.4 16.5 3.3 8.0 11.4 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Daxx PF03344.10 EIE81980.1 - 3.7 5.9 16.1 7.4 4.9 11.2 1.4 1 0 0 1 1 1 0 Daxx Family FYDLN_acid PF09538.5 EIE81980.1 - 7.6 7.1 21.5 0.05 14.1 8.4 2.1 3 0 0 3 3 2 0 Protein of unknown function (FYDLN_acid) Clathrin PF00637.15 EIE81981.1 - 8.1e-22 77.3 11.3 9.1e-17 60.9 1.7 3.2 3 0 0 3 3 3 2 Region in Clathrin and VPS Vps8 PF12816.2 EIE81981.1 - 0.00091 18.5 2.6 0.12 11.5 0.3 2.4 2 0 0 2 2 2 2 Golgi CORVET complex core vacuolar protein 8 DUF4346 PF14251.1 EIE81981.1 - 0.016 14.9 0.1 0.044 13.5 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4346) Phage_GP20 PF06810.6 EIE81981.1 - 0.028 13.8 5.5 1.3 8.4 1.0 2.5 2 0 0 2 2 2 0 Phage minor structural protein GP20 TPR_11 PF13414.1 EIE81981.1 - 0.082 12.5 3.6 0.13 11.9 0.0 3.1 4 0 0 4 4 4 0 TPR repeat TPR_2 PF07719.12 EIE81981.1 - 1.6 8.8 6.6 22 5.2 0.1 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat 2OG-FeII_Oxy_2 PF13532.1 EIE81982.1 - 1.1e-11 45.0 0.0 1.1e-11 44.8 0.0 1.0 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EIE81982.1 - 9.1e-05 22.6 0.0 0.00011 22.4 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Phosphorylase PF00343.15 EIE81983.1 - 2.7e-281 934.6 0.1 3.6e-281 934.2 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate phosphorylase Citrate_synt PF00285.16 EIE81984.1 - 1.1e-104 350.0 0.0 1.3e-104 349.7 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase Eclosion PF04736.7 EIE81984.1 - 0.11 11.8 0.0 0.29 10.6 0.0 1.6 2 0 0 2 2 2 0 Eclosion hormone SH3_2 PF07653.12 EIE81985.1 - 1e-11 44.1 0.0 1.9e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EIE81985.1 - 1e-11 44.1 0.1 1.5e-11 43.6 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EIE81985.1 - 1.9e-10 39.9 0.1 2.9e-10 39.3 0.1 1.3 1 0 0 1 1 1 1 SH3 domain Peptidase_M17 PF00883.16 EIE81986.1 - 2.3e-117 391.3 0.0 3e-117 390.9 0.0 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.12 EIE81986.1 - 0.0053 16.5 0.1 0.0096 15.6 0.1 1.4 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain DUF260 PF03195.9 EIE81986.1 - 0.079 13.2 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF260 Peptidase_C97 PF05903.9 EIE81988.1 - 1.2e-26 93.2 0.0 1.5e-26 92.9 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain PP1_inhibitor PF05361.7 EIE81988.1 - 0.063 12.9 0.1 0.18 11.5 0.0 1.6 2 0 0 2 2 2 0 PKC-activated protein phosphatase-1 inhibitor LRAT PF04970.8 EIE81988.1 - 0.15 12.0 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Lecithin retinol acyltransferase HSF_DNA-bind PF00447.12 EIE81989.1 - 5.2e-30 103.6 0.7 1e-29 102.7 0.5 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding ATG16 PF08614.6 EIE81989.1 - 0.041 13.7 2.2 0.057 13.2 1.5 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Pro_isomerase PF00160.16 EIE81990.1 - 1.9e-47 161.3 0.2 2.1e-47 161.1 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Attractin PF08037.6 EIE81992.1 - 0.034 13.9 0.5 0.077 12.7 0.4 1.7 1 0 0 1 1 1 0 Attractin family Lipase_GDSL PF00657.17 EIE81994.1 - 3.6e-11 43.3 0.9 2.8e-10 40.4 0.6 2.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EIE81994.1 - 2.6e-06 27.6 0.0 1.3e-05 25.4 0.0 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family PYRIN PF02758.11 EIE81995.1 - 0.12 12.0 0.3 4.3 7.0 0.2 2.6 1 1 0 1 1 1 0 PAAD/DAPIN/Pyrin domain CAF1A PF12253.3 EIE81996.1 - 3.6e-24 84.6 3.4 9.3e-24 83.3 2.4 1.7 1 0 0 1 1 1 1 Chromatin assembly factor 1 subunit A YafO_toxin PF13957.1 EIE81996.1 - 0.076 12.8 0.0 0.22 11.3 0.0 1.7 1 1 0 1 1 1 0 Toxin YafO, type II toxin-antitoxin system ANTH PF07651.11 EIE81997.1 - 0.0057 15.3 0.1 0.0085 14.8 0.1 1.3 1 0 0 1 1 1 1 ANTH domain DUF3402 PF11882.3 EIE81998.1 - 7.6e-11 41.6 2.3 1.2e-10 41.0 1.6 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3402) AMPKBI PF04739.10 EIE81998.1 - 0.096 12.5 0.6 0.22 11.4 0.0 1.9 2 1 0 2 2 2 0 5'-AMP-activated protein kinase beta subunit, interation domain Abhydro_lipase PF04083.11 EIE82001.1 - 8e-18 63.5 0.1 1.8e-17 62.4 0.1 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 EIE82001.1 - 1e-16 61.2 0.2 1.5e-16 60.7 0.2 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EIE82001.1 - 7.3e-08 32.5 0.1 1.2e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIE82001.1 - 1.6e-06 27.8 0.0 6.7e-06 25.9 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EIE82001.1 - 0.096 12.1 0.0 2.2 7.6 0.0 2.4 2 1 0 2 2 2 0 Serine hydrolase (FSH1) FKBP_C PF00254.23 EIE82004.1 - 1.1e-20 73.3 0.0 1.6e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase NOGCT PF08155.6 EIE82005.1 - 1.1e-29 101.8 1.3 3.3e-29 100.3 0.9 1.9 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.9 EIE82005.1 - 1.5e-29 101.6 0.4 3.4e-29 100.5 0.3 1.7 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.18 EIE82005.1 - 1.3e-18 67.0 0.0 3e-18 65.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EIE82005.1 - 5.7e-10 38.6 0.0 1.3e-09 37.5 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 EIE82005.1 - 9.8e-07 29.2 0.0 7.3e-06 26.4 0.0 2.5 3 0 0 3 3 3 1 Miro-like protein GTP_EFTU PF00009.22 EIE82005.1 - 0.00051 19.5 0.9 0.013 14.9 0.6 2.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AIG1 PF04548.11 EIE82005.1 - 0.00089 18.4 0.0 0.0019 17.3 0.0 1.6 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.18 EIE82005.1 - 0.0014 18.5 0.4 1.1 9.1 0.0 3.3 2 1 1 3 3 3 2 Dynamin family DUF258 PF03193.11 EIE82005.1 - 0.0085 15.2 0.0 0.064 12.4 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EIE82005.1 - 0.011 15.8 0.0 0.053 13.6 0.0 2.2 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.15 EIE82005.1 - 0.016 13.8 0.0 0.016 13.8 0.0 2.7 3 1 1 5 5 5 0 G-protein alpha subunit PRKCSH-like PF12999.2 EIE82006.1 - 9.6e-33 113.2 10.4 1.6e-32 112.4 7.2 1.3 1 0 0 1 1 1 1 Glucosidase II beta subunit-like DUF641 PF04859.7 EIE82006.1 - 0.4 10.4 3.3 0.63 9.7 2.3 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) DIM PF08194.7 EIE82006.1 - 0.63 10.0 2.8 1.3 9.0 2.0 1.5 1 0 0 1 1 1 0 DIM protein FH2 PF02181.18 EIE82009.1 - 2.5e-50 171.4 8.0 1.1e-34 120.0 0.0 2.6 2 1 1 3 3 3 2 Formin Homology 2 Domain Drf_GBD PF06371.8 EIE82009.1 - 7.1e-36 123.3 1.2 7.1e-36 123.3 0.9 3.2 2 1 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 EIE82009.1 - 3.3e-10 39.7 0.1 3.3e-10 39.7 0.1 3.0 3 0 0 3 3 3 1 Diaphanous FH3 Domain HTH_23 PF13384.1 EIE82010.1 - 0.00028 20.4 0.0 0.0003 20.3 0.0 1.2 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.1 EIE82010.1 - 0.0041 17.0 0.0 0.0047 16.8 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.1 EIE82010.1 - 0.0061 16.7 0.0 0.007 16.4 0.0 1.1 1 0 0 1 1 1 1 Winged helix-turn helix HTH_Crp_2 PF13545.1 EIE82010.1 - 0.018 14.8 0.0 0.02 14.6 0.0 1.3 1 1 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_7 PF02796.10 EIE82010.1 - 0.02 14.7 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_38 PF13936.1 EIE82010.1 - 0.062 12.8 0.0 0.078 12.5 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain FtsK_SpoIIIE PF01580.13 EIE82011.1 - 0.0061 16.0 0.1 0.0091 15.4 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family SseC PF04888.7 EIE82011.1 - 0.0095 15.3 0.1 0.015 14.6 0.1 1.3 1 0 0 1 1 1 1 Secretion system effector C (SseC) like family Macoilin PF09726.4 EIE82011.1 - 0.026 12.8 5.8 0.033 12.4 4.0 1.1 1 0 0 1 1 1 0 Transmembrane protein Striatin PF08232.7 EIE82011.1 - 0.056 13.7 5.1 0.14 12.4 3.6 1.7 1 0 0 1 1 1 0 Striatin family Phlebovirus_NSM PF07246.6 EIE82011.1 - 0.11 11.6 3.1 0.1 11.7 0.4 1.9 1 1 1 2 2 2 0 Phlebovirus nonstructural protein NS-M DUF641 PF04859.7 EIE82011.1 - 0.29 10.8 6.1 0.041 13.6 0.8 2.0 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) DivIC PF04977.10 EIE82011.1 - 1.1 8.7 9.8 0.18 11.3 2.6 2.4 2 0 0 2 2 2 0 Septum formation initiator DUF2681 PF10883.3 EIE82011.1 - 2 8.6 8.7 0.1 12.8 1.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) TMF_TATA_bd PF12325.3 EIE82011.1 - 2.5 7.8 9.1 0.22 11.2 0.7 3.0 3 1 0 3 3 3 0 TATA element modulatory factor 1 TATA binding Atg14 PF10186.4 EIE82011.1 - 4.4 6.1 13.9 5.8 5.7 8.5 2.1 2 1 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF2203 PF09969.4 EIE82011.1 - 7.7 6.7 6.6 26 5.0 3.6 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DDE_3 PF13358.1 EIE82012.1 - 6.7e-13 48.6 0.0 1.3e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE82012.1 - 2.3e-11 43.6 1.1 3.8e-11 42.8 0.2 1.8 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 EIE82012.1 - 0.014 15.5 0.4 0.031 14.4 0.0 1.8 2 0 0 2 2 2 0 Winged helix-turn helix HTH_23 PF13384.1 EIE82012.1 - 0.017 14.7 0.1 0.042 13.4 0.1 1.7 1 0 0 1 1 1 0 Homeodomain-like domain HTH_30 PF13556.1 EIE82012.1 - 0.05 13.1 0.0 0.51 9.9 0.0 2.2 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain DDE_3 PF13358.1 EIE82014.1 - 3.5e-20 72.2 0.1 7.2e-20 71.2 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE82014.1 - 2e-07 30.9 1.4 2e-07 30.9 1.0 2.3 1 1 1 2 2 2 1 Transposase rve PF00665.21 EIE82014.1 - 0.037 14.1 0.1 0.089 12.8 0.0 1.9 1 1 0 1 1 1 0 Integrase core domain HTH_12 PF08461.5 EIE82014.1 - 0.086 12.5 0.1 0.28 10.9 0.0 1.8 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain HTH_29 PF13551.1 EIE82014.1 - 0.21 11.7 2.9 0.19 11.8 0.8 1.9 2 0 0 2 2 2 0 Winged helix-turn helix DUF1033 PF06279.6 EIE82014.1 - 0.36 10.6 0.0 0.36 10.6 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1033) NFRKB_winged PF14465.1 EIE82014.1 - 0.37 10.6 3.4 5.5 6.8 0.4 2.9 2 1 0 2 2 2 0 NFRKB Winged Helix-like HTH_32 PF13565.1 EIE82014.1 - 0.96 10.2 7.5 0.19 12.5 1.1 2.7 4 0 0 4 4 4 0 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.1 EIE82014.1 - 1.6 7.9 3.7 1.1 8.5 0.1 2.4 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 DDE_3 PF13358.1 EIE82016.1 - 4.7e-14 52.3 0.0 7.1e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE82017.1 - 1.6e-18 66.5 0.6 1.6e-18 66.5 0.4 2.1 2 1 0 2 2 2 1 Transposase HTH_29 PF13551.1 EIE82017.1 - 3.8e-07 30.2 0.9 8.4e-07 29.1 0.6 1.5 1 1 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.1 EIE82017.1 - 0.00017 22.3 4.4 0.00024 21.8 0.2 2.8 2 2 1 3 3 3 1 Homeodomain-like domain HTH_23 PF13384.1 EIE82017.1 - 0.009 15.6 1.9 0.1 12.2 0.0 2.9 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.1 EIE82017.1 - 0.068 13.2 0.1 0.24 11.4 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain DDE_3 PF13358.1 EIE82018.1 - 3.6e-12 46.2 0.2 4.7e-12 45.8 0.2 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF3863 PF12979.2 EIE82018.1 - 0.11 11.1 0.1 0.13 10.8 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3863) rve PF00665.21 EIE82018.1 - 0.13 12.3 0.0 0.29 11.2 0.0 1.6 2 0 0 2 2 2 0 Integrase core domain HTH_Tnp_4 PF13613.1 EIE82019.1 - 0.0001 21.7 0.0 0.00017 21.0 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease HTH_23 PF13384.1 EIE82019.1 - 0.00057 19.4 0.1 0.0011 18.5 0.0 1.6 2 0 0 2 2 2 1 Homeodomain-like domain HTH_30 PF13556.1 EIE82019.1 - 0.04 13.5 0.0 0.095 12.3 0.0 1.6 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain RecX PF02631.11 EIE82019.1 - 0.096 12.9 0.1 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 RecX family rve PF00665.21 EIE82020.1 - 3.7e-27 94.8 0.0 1.3e-26 93.0 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.1 EIE82020.1 - 1.3e-05 24.6 0.1 5.1e-05 22.7 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.5 EIE82020.1 - 0.0027 17.0 0.1 0.013 14.9 0.0 2.2 2 0 0 2 2 2 1 His(2)-Cys(2) zinc finger Viral_helicase1 PF01443.13 EIE82021.1 - 0.19 11.1 4.7 0.27 10.7 3.2 1.1 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AIF-MLS PF14962.1 EIE82021.1 - 0.89 9.1 7.1 1.1 8.8 4.9 1.2 1 0 0 1 1 1 0 Mitochondria Localisation Sequence DUF2149 PF09919.4 EIE82021.1 - 9.4 6.4 6.0 5.3 7.1 0.6 2.3 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2149) Asp_protease_2 PF13650.1 EIE82022.1 - 2.4e-06 27.9 0.1 5.7e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 EIE82022.1 - 7.4e-06 25.8 0.0 1.9e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EIE82022.1 - 4.6e-05 23.1 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.5 EIE82022.1 - 0.018 14.5 0.0 0.062 12.8 0.0 1.9 1 0 0 1 1 1 0 Aspartyl protease RVT_1 PF00078.22 EIE82024.1 - 1e-21 77.2 0.1 1.8e-21 76.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.12 EIE82024.1 - 8.8e-08 32.1 0.2 2.1e-07 30.9 0.2 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein Asp_protease_2 PF13650.1 EIE82024.1 - 1.1e-07 32.2 0.1 3.8e-07 30.5 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EIE82024.1 - 7.9e-06 25.6 0.1 2.2e-05 24.1 0.1 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.18 EIE82024.1 - 0.00094 19.0 1.0 0.0018 18.1 0.7 1.5 1 0 0 1 1 1 1 Zinc knuckle Autophagy_N PF03986.8 EIE82024.1 - 0.025 14.3 0.3 0.053 13.2 0.2 1.5 1 0 0 1 1 1 0 Autophagocytosis associated protein (Atg3), N-terminal domain RVP PF00077.15 EIE82024.1 - 0.12 12.2 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease LAT PF15234.1 EIE82024.1 - 1.2 8.5 7.0 3 7.2 1.3 2.3 2 0 0 2 2 2 0 Linker for activation of T-cells Med15 PF09606.5 EIE82025.1 - 0.028 12.6 12.5 0.04 12.1 8.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal FlgM PF04316.8 EIE82025.1 - 2.2 8.2 5.1 13 5.8 2.9 2.3 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM Transposase_21 PF02992.9 EIE82026.1 - 6.2e-22 77.7 0.0 1.3e-21 76.7 0.0 1.5 1 0 0 1 1 1 1 Transposase family tnp2 DUF1258 PF06869.7 EIE82026.1 - 0.0025 16.9 0.0 0.0041 16.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) PC4 PF02229.11 EIE82029.1 - 0.096 11.9 0.0 0.2 10.9 0.0 1.6 1 0 0 1 1 1 0 Transcriptional Coactivator p15 (PC4) HTH_Tnp_Tc3_2 PF01498.13 EIE82030.1 - 3e-08 33.6 0.6 5.7e-08 32.7 0.4 1.4 1 0 0 1 1 1 1 Transposase HTH_Tnp_Tc3_2 PF01498.13 EIE82031.1 - 1e-07 31.8 0.2 5.8e-07 29.4 0.0 2.1 2 0 0 2 2 2 1 Transposase rve PF00665.21 EIE82032.1 - 6.3e-19 68.2 0.0 1.5e-18 66.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE82032.1 - 3.7e-17 62.4 0.4 1.1e-16 60.8 0.1 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Cass2 PF14526.1 EIE82032.1 - 0.097 12.6 0.6 2.7 8.0 0.0 3.3 3 1 1 4 4 4 0 Integron-associated effector binding protein DDE_3 PF13358.1 EIE82035.1 - 4.7e-20 71.8 0.1 8.5e-20 70.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE82035.1 - 2.4e-08 33.9 2.9 3.1e-08 33.5 0.3 2.3 1 1 1 2 2 2 1 Transposase rve PF00665.21 EIE82035.1 - 0.043 13.9 0.1 0.11 12.5 0.0 1.8 2 0 0 2 2 2 0 Integrase core domain HTH_12 PF08461.5 EIE82035.1 - 0.11 12.2 0.1 0.34 10.6 0.0 1.8 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain HTH_29 PF13551.1 EIE82035.1 - 0.22 11.6 2.9 0.23 11.6 0.8 2.0 2 1 0 2 2 2 0 Winged helix-turn helix HTH_32 PF13565.1 EIE82035.1 - 0.95 10.3 6.3 0.27 12.0 0.6 2.7 4 0 0 4 4 4 0 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.1 EIE82035.1 - 1.8 7.8 3.8 1.1 8.5 0.1 2.4 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 RVT_1 PF00078.22 EIE82036.1 - 5.7e-12 45.4 0.2 1e-11 44.6 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.12 EIE82038.1 - 0.00053 20.0 0.8 0.0012 18.8 0.1 1.9 2 0 0 2 2 2 1 Retrotransposon gag protein SseC PF04888.7 EIE82039.1 - 1.4 8.2 12.4 1.8 7.7 3.7 2.3 1 1 1 2 2 2 0 Secretion system effector C (SseC) like family UPF0014 PF03649.8 EIE82040.1 - 3.3e-43 147.6 14.9 4.2e-43 147.3 10.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0014) FtsX PF02687.16 EIE82040.1 - 0.00032 20.4 6.5 0.00032 20.4 4.5 3.0 1 1 1 2 2 2 1 FtsX-like permease family Cyto_ox_2 PF02322.10 EIE82040.1 - 0.31 10.1 9.2 0.86 8.7 1.8 2.3 2 0 0 2 2 2 0 Cytochrome oxidase subunit II IIGP PF05049.8 EIE82041.1 - 1.3e-23 83.4 0.0 1.9e-23 82.8 0.0 1.2 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) MMR_HSR1 PF01926.18 EIE82041.1 - 1.8e-10 40.8 0.0 2.4e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EIE82041.1 - 8.7e-08 32.6 0.0 1.5e-07 31.8 0.0 1.4 1 1 0 1 1 1 1 Miro-like protein Dynamin_N PF00350.18 EIE82041.1 - 2e-05 24.5 0.5 0.0029 17.4 0.6 2.1 1 1 1 2 2 2 1 Dynamin family DUF258 PF03193.11 EIE82041.1 - 5.8e-05 22.3 0.0 8.1e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 EIE82041.1 - 0.0002 20.6 0.0 0.00031 20.0 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EIE82041.1 - 0.00023 20.6 0.0 0.06 12.7 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 EIE82041.1 - 0.00028 21.1 0.0 0.00041 20.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_28 PF13521.1 EIE82041.1 - 0.0007 19.5 0.0 0.0017 18.3 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EIE82041.1 - 0.0011 19.0 0.0 0.0016 18.4 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 EIE82041.1 - 0.0016 17.8 0.1 0.0033 16.9 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Gtr1_RagA PF04670.7 EIE82041.1 - 0.0018 17.4 0.0 0.0022 17.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AIG1 PF04548.11 EIE82041.1 - 0.004 16.2 0.0 0.005 15.9 0.0 1.2 1 0 0 1 1 1 1 AIG1 family DUF815 PF05673.8 EIE82041.1 - 0.004 16.1 0.0 0.0054 15.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 EIE82041.1 - 0.0043 17.8 0.2 0.0069 17.2 0.2 1.5 1 1 0 1 1 1 1 AAA domain TrwB_AAD_bind PF10412.4 EIE82041.1 - 0.0069 15.0 0.0 0.009 14.6 0.0 1.1 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain SMC_N PF02463.14 EIE82041.1 - 0.0091 15.2 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain cobW PF02492.14 EIE82041.1 - 0.014 14.8 0.0 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_21 PF13304.1 EIE82041.1 - 0.015 15.2 0.0 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EIE82041.1 - 0.02 14.3 0.0 0.031 13.7 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family MobB PF03205.9 EIE82041.1 - 0.022 14.4 0.0 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 EIE82041.1 - 0.025 14.7 0.0 0.055 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Ras PF00071.17 EIE82041.1 - 0.027 13.8 0.0 0.048 13.0 0.0 1.6 1 1 0 1 1 1 0 Ras family AAA_10 PF12846.2 EIE82041.1 - 0.027 13.9 0.0 0.036 13.4 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain T2SE PF00437.15 EIE82041.1 - 0.029 13.2 0.0 0.035 12.9 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein Septin PF00735.13 EIE82041.1 - 0.029 13.3 0.0 0.04 12.9 0.0 1.1 1 0 0 1 1 1 0 Septin Guanylate_kin PF00625.16 EIE82041.1 - 0.052 12.9 0.0 0.15 11.4 0.0 1.7 2 0 0 2 2 2 0 Guanylate kinase DUF87 PF01935.12 EIE82041.1 - 0.059 13.1 0.1 0.092 12.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF87 IstB_IS21 PF01695.12 EIE82041.1 - 0.064 12.6 0.0 0.098 12.0 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein GBP PF02263.14 EIE82041.1 - 0.097 11.7 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain AAA_23 PF13476.1 EIE82041.1 - 0.11 12.7 0.1 0.18 12.1 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EIE82041.1 - 0.16 12.2 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain HEAT PF02985.17 EIE82043.1 - 0.0011 18.8 0.1 0.025 14.6 0.0 2.6 2 0 0 2 2 2 1 HEAT repeat DUF1494 PF07379.6 EIE82043.1 - 0.044 13.6 0.2 0.089 12.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1494) Cas_Cas5d PF09704.5 EIE82043.1 - 0.072 12.7 0.0 0.2 11.2 0.0 1.5 1 1 0 1 1 1 0 CRISPR-associated protein (Cas_Cas5) zf-TFIIB PF13453.1 EIE82043.1 - 0.51 9.5 4.9 0.19 10.9 0.6 2.2 2 0 0 2 2 2 0 Transcription factor zinc-finger HLH PF00010.21 EIE82047.1 - 1.7e-17 62.8 1.7 3.7e-17 61.7 0.1 2.5 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF4524 PF15025.1 EIE82047.1 - 0.0087 15.5 0.5 0.083 12.3 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4524) Atrophin-1 PF03154.10 EIE82047.1 - 0.21 9.7 4.3 0.32 9.1 3.0 1.2 1 0 0 1 1 1 0 Atrophin-1 family MIR PF02815.14 EIE82048.1 - 3e-18 66.0 0.2 5.7e-14 52.0 0.1 2.2 1 1 1 2 2 2 2 MIR domain Ins145_P3_rec PF08709.6 EIE82048.1 - 9.6e-09 34.5 0.0 2.3e-07 30.0 0.0 2.1 2 0 0 2 2 2 2 Inositol 1,4,5-trisphosphate/ryanodine receptor MFS_1 PF07690.11 EIE82049.1 - 2.9e-28 98.5 26.4 1.6e-23 82.9 9.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIE82049.1 - 1.1e-05 24.1 34.0 0.00014 20.6 7.3 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter YrhC PF14143.1 EIE82049.1 - 0.41 10.6 5.1 0.11 12.4 0.5 2.3 3 0 0 3 3 3 0 YrhC-like protein DUF962 PF06127.6 EIE82049.1 - 6.1 6.8 6.9 0.46 10.3 0.6 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF962) Pkinase PF00069.20 EIE82050.1 - 5.7e-17 61.7 0.6 1.5e-16 60.3 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE82050.1 - 0.015 14.4 0.0 0.074 12.1 0.0 2.0 1 1 0 1 1 1 0 Protein tyrosine kinase GAS PF13851.1 EIE82051.1 - 0.0042 16.2 25.4 0.0042 16.2 17.6 2.0 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding DUF3870 PF12986.2 EIE82051.1 - 0.037 14.2 1.1 0.095 12.9 0.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3870) ERM PF00769.14 EIE82051.1 - 0.11 11.9 31.1 0.044 13.3 3.5 2.7 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF727 PF05303.7 EIE82051.1 - 0.11 12.2 1.8 0.66 9.7 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF727) DUF948 PF06103.6 EIE82051.1 - 0.66 9.8 17.0 8.7 6.2 3.6 4.3 1 1 2 4 4 4 0 Bacterial protein of unknown function (DUF948) Tropomyosin_1 PF12718.2 EIE82051.1 - 1.2 9.0 31.8 2.7 7.8 10.8 3.4 1 1 2 3 3 3 0 Tropomyosin like FlaC_arch PF05377.6 EIE82051.1 - 1.3 8.9 8.7 15 5.5 0.5 3.7 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) HsbA PF12296.3 EIE82051.1 - 1.6 8.5 7.8 1.7 8.5 2.1 2.3 2 0 0 2 2 2 0 Hydrophobic surface binding protein A Reo_sigmaC PF04582.7 EIE82051.1 - 2.1 7.4 6.6 0.63 9.1 2.0 1.8 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF1759 PF03564.10 EIE82051.1 - 2.2 8.0 12.7 0.48 10.2 1.0 3.1 2 2 1 3 3 3 0 Protein of unknown function (DUF1759) Relaxase PF03432.9 EIE82051.1 - 2.5 7.4 15.0 0.64 9.3 8.0 1.6 1 1 1 2 2 2 0 Relaxase/Mobilisation nuclease domain DUF3573 PF12097.3 EIE82051.1 - 4.8 5.6 10.5 0.28 9.7 3.8 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3573) APG6 PF04111.7 EIE82051.1 - 5.4 5.9 32.2 1.4 7.8 16.3 2.5 1 1 2 3 3 3 0 Autophagy protein Apg6 FliD_N PF02465.13 EIE82051.1 - 7.3 7.0 15.2 4.5 7.7 2.6 3.5 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 N-terminus DUF2570 PF10828.3 EIE82051.1 - 7.3 6.2 18.4 2.7 7.6 5.4 2.9 1 1 0 2 2 2 0 Protein of unknown function (DUF2570) UPF0014 PF03649.8 EIE82052.1 - 8.5e-20 70.9 4.7 1e-19 70.7 3.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0014) TFR_dimer PF04253.10 EIE82054.1 - 5.3e-22 77.7 0.0 8.7e-22 77.0 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 EIE82054.1 - 7.3e-21 74.7 0.0 1.3e-20 73.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EIE82054.1 - 1.7e-05 24.4 0.0 3.4e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.23 EIE82054.1 - 0.0012 18.4 0.0 0.0025 17.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Cast PF10174.4 EIE82054.1 - 0.1 10.6 0.0 0.14 10.1 0.0 1.1 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone CNH PF00780.17 EIE82055.1 - 1.1e-13 51.3 0.7 1.7e-13 50.6 0.1 1.6 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.1 EIE82055.1 - 1.9e-13 50.5 3.1 4.8e-13 49.2 0.3 2.6 2 1 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 EIE82055.1 - 0.014 15.5 0.0 0.17 12.1 0.0 2.5 2 1 0 2 2 2 0 PH domain DDDD PF10161.4 EIE82055.1 - 0.098 12.2 0.0 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 Putative mitochondrial precursor protein RhoGEF PF00621.15 EIE82056.1 - 2.9e-21 76.1 1.9 5.4e-21 75.2 1.3 1.4 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.16 EIE82056.1 - 0.00014 21.5 0.1 0.00029 20.4 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) SPX PF03105.14 EIE82058.1 - 0.00098 18.9 0.0 0.0012 18.7 0.0 1.1 1 0 0 1 1 1 1 SPX domain Peptidase_M13_N PF05649.8 EIE82059.1 - 2.1e-30 106.0 0.0 1.2e-14 54.2 0.0 2.2 1 1 1 2 2 2 2 Peptidase family M13 Peptidase_M13 PF01431.16 EIE82059.1 - 1.5e-05 24.2 0.4 0.00016 20.9 0.3 2.3 1 1 0 1 1 1 1 Peptidase family M13 BAR PF03114.13 EIE82060.1 - 6.8e-36 123.9 8.4 1e-35 123.3 5.8 1.3 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.1 EIE82060.1 - 5.5e-16 57.8 0.1 1e-15 57.0 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EIE82060.1 - 4.7e-15 54.7 0.3 9.8e-15 53.6 0.2 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EIE82060.1 - 4.7e-14 51.6 0.1 1.1e-13 50.4 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain DUF605 PF04652.11 EIE82060.1 - 0.11 11.8 16.6 0.17 11.2 11.5 1.4 1 0 0 1 1 1 0 Vta1 like Menin PF05053.8 EIE82060.1 - 0.35 8.9 9.7 0.54 8.3 6.7 1.2 1 0 0 1 1 1 0 Menin WD40 PF00400.27 EIE82062.1 - 8.3e-37 123.7 23.6 1.1e-05 25.1 0.0 11.0 11 0 0 11 11 11 8 WD domain, G-beta repeat eIF2A PF08662.6 EIE82062.1 - 0.0033 17.1 0.0 0.021 14.5 0.0 2.3 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A DUF3639 PF12341.3 EIE82062.1 - 1.1 9.2 4.0 0.7 9.9 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3639) Glyco_transf_8 PF01501.15 EIE82063.1 - 5.5e-30 104.5 3.5 6.8e-30 104.2 2.4 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 EIE82063.1 - 0.0083 15.4 0.1 0.027 13.8 0.0 1.8 2 0 0 2 2 2 1 Mannosyltransferase putative DUF2012 PF09430.5 EIE82064.1 - 2.4e-26 91.9 0.0 3.3e-26 91.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) CarboxypepD_reg PF13620.1 EIE82064.1 - 6.2e-07 29.3 0.0 9.7e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain fn3_3 PF14686.1 EIE82064.1 - 0.00024 21.1 0.0 0.00043 20.3 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II DUF4480 PF13715.1 EIE82064.1 - 0.0025 17.8 0.1 0.0048 16.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4480) Cna_B PF05738.8 EIE82064.1 - 0.018 14.7 0.0 0.042 13.6 0.0 1.6 1 1 0 1 1 1 0 Cna protein B-type domain Y_Y_Y PF07495.8 EIE82064.1 - 0.071 12.8 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 Y_Y_Y domain TauD PF02668.11 EIE82065.1 - 1e-58 199.0 0.5 1.4e-58 198.6 0.4 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.7 EIE82065.1 - 0.00012 22.4 0.0 0.00061 20.1 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF971) CsiD PF08943.5 EIE82065.1 - 0.0076 15.1 0.1 0.011 14.6 0.1 1.2 1 0 0 1 1 1 1 CsiD DUF692 PF05114.8 EIE82065.1 - 0.083 11.7 0.0 0.15 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF692) Cyclin PF08613.6 EIE82066.1 - 1.2e-35 123.1 0.1 1.7e-35 122.6 0.1 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EIE82066.1 - 0.043 13.3 0.0 0.077 12.5 0.0 1.4 1 1 0 1 1 1 0 Cyclin, N-terminal domain DUF1987 PF09345.5 EIE82066.1 - 0.11 12.2 0.2 0.27 11.0 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1987) zf-C2H2_4 PF13894.1 EIE82068.1 - 0.034 14.4 0.4 0.11 12.9 0.1 1.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EIE82068.1 - 0.092 12.9 1.3 0.092 12.9 0.9 1.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding YokU PF14122.1 EIE82068.1 - 0.097 12.4 0.1 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 YokU-like protein zf-C2H2 PF00096.21 EIE82068.1 - 0.11 12.8 1.6 0.33 11.3 0.4 2.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EIE82068.1 - 0.26 11.2 0.7 0.26 11.2 0.5 1.7 2 0 0 2 2 2 0 C2H2-type zinc finger XRN_N PF03159.13 EIE82069.1 - 1.6e-104 348.4 0.0 3e-104 347.5 0.0 1.5 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus zf-CCHC PF00098.18 EIE82069.1 - 0.021 14.7 1.1 0.041 13.8 0.8 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 EIE82069.1 - 0.064 12.9 0.7 0.17 11.5 0.5 1.8 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.22 EIE82070.1 - 5.9e-27 94.4 0.0 1.4e-26 93.2 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EIE82070.1 - 7.1e-18 64.3 2.2 2.7e-17 62.4 1.5 2.1 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EIE82070.1 - 1.2e-07 31.9 0.1 2.8e-07 30.7 0.1 1.7 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Lar_restr_allev PF14354.1 EIE82070.1 - 0.018 15.3 1.5 0.039 14.2 0.4 2.1 2 0 0 2 2 2 0 Restriction alleviation protein Lar Zn_Tnp_IS1595 PF12760.2 EIE82070.1 - 0.19 11.5 2.4 0.61 9.9 1.6 1.9 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.5 EIE82070.1 - 0.56 10.2 2.4 23 5.0 0.1 2.7 2 0 0 2 2 2 0 Zinc ribbon domain DDE_3 PF13358.1 EIE82071.1 - 7.8e-33 113.2 0.0 1.7e-32 112.1 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 EIE82071.1 - 9e-10 38.6 0.0 2e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.1 EIE82071.1 - 2.1e-08 34.0 0.0 1.2e-07 31.5 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.1 EIE82071.1 - 1.1e-07 31.2 0.0 1.3e-05 24.6 0.0 2.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_17 PF12728.2 EIE82071.1 - 6.1e-06 26.3 0.0 0.0017 18.5 0.0 2.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_32 PF13565.1 EIE82071.1 - 1.4e-05 25.8 0.0 5e-05 24.0 0.0 2.1 1 0 0 1 1 1 1 Homeodomain-like domain DDE_1 PF03184.14 EIE82071.1 - 0.0001 21.4 1.2 0.0032 16.6 0.8 2.5 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_1 PF01527.15 EIE82071.1 - 0.00055 19.8 0.2 0.0027 17.6 0.0 2.2 2 0 0 2 2 2 1 Transposase LZ_Tnp_IS481 PF13011.1 EIE82071.1 - 0.001 19.3 0.0 0.0027 17.9 0.0 1.7 1 0 0 1 1 1 1 leucine-zipper of insertion element IS481 rve PF00665.21 EIE82071.1 - 0.0027 17.7 0.1 0.023 14.8 0.0 2.5 3 0 0 3 3 3 1 Integrase core domain HTH_38 PF13936.1 EIE82071.1 - 0.0084 15.6 0.0 0.3 10.6 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain Terminase_1 PF03354.10 EIE82071.1 - 0.036 12.4 0.0 0.058 11.8 0.0 1.2 1 0 0 1 1 1 0 Phage Terminase HTH_30 PF13556.1 EIE82071.1 - 0.072 12.6 0.2 0.25 10.9 0.0 2.0 3 0 0 3 3 2 0 PucR C-terminal helix-turn-helix domain HTH_Tnp_IS630 PF01710.11 EIE82071.1 - 0.2 11.3 3.2 1 9.0 0.1 3.0 2 1 1 3 3 3 0 Transposase zf-C2H2_4 PF13894.1 EIE82072.1 - 0.0016 18.5 0.6 0.0056 16.9 0.4 2.0 1 0 0 1 1 1 1 C2H2-type zinc finger EF-hand_6 PF13405.1 EIE82073.1 - 0.089 12.7 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 EF-hand domain INTS2 PF14750.1 EIE82074.1 - 0.0021 15.6 0.1 0.0025 15.4 0.1 1.0 1 0 0 1 1 1 1 Integrator complex subunit 2 RVT_1 PF00078.22 EIE82075.1 - 1.9e-26 92.7 0.0 3.1e-26 92.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2360 PF10152.4 EIE82076.1 - 0.019 15.2 0.9 0.019 15.2 0.6 2.0 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Herpes_BLRF2 PF05812.7 EIE82076.1 - 0.032 14.0 0.2 2.2 8.1 0.0 2.6 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein MULE PF10551.4 EIE82077.1 - 2.5e-08 33.9 0.0 6.1e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain INTS2 PF14750.1 EIE82080.1 - 0.0021 15.6 0.1 0.0025 15.4 0.1 1.0 1 0 0 1 1 1 1 Integrator complex subunit 2 Gly_transf_sug PF04488.10 EIE82084.1 - 1.4e-07 31.8 0.0 2.6e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 EIE82084.1 - 0.0015 17.7 0.8 0.0023 17.1 0.6 1.3 1 1 0 1 1 1 1 Capsular polysaccharide synthesis protein TINF2_N PF14973.1 EIE82085.1 - 0.017 15.2 0.4 0.079 13.0 0.2 1.9 2 0 0 2 2 2 0 TERF1-interacting nuclear factor 2 N-terminus Glyco_hydro_63 PF03200.11 EIE82088.1 - 1.7e-59 201.5 0.8 1.9e-59 201.3 0.5 1.0 1 0 0 1 1 1 1 Mannosyl oligosaccharide glucosidase FtsJ PF01728.14 EIE82089.1 - 9.3e-50 169.1 0.0 1.3e-49 168.6 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase 2-Hacid_dh_C PF02826.14 EIE82089.1 - 9.1e-40 135.6 0.0 1.7e-20 72.9 0.0 2.3 1 1 1 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EIE82089.1 - 9.1e-17 60.7 0.0 1.4e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Methyltransf_31 PF13847.1 EIE82089.1 - 0.00013 21.6 0.0 0.00083 18.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Shikimate_DH PF01488.15 EIE82089.1 - 0.001 19.1 0.0 0.027 14.5 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.10 EIE82089.1 - 0.0011 18.8 0.1 0.032 14.0 0.0 2.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EIE82089.1 - 0.0031 17.9 0.1 0.01 16.2 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Methyltransf_26 PF13659.1 EIE82089.1 - 0.015 15.3 0.0 0.035 14.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain IlvN PF07991.7 EIE82089.1 - 0.018 14.4 0.0 0.034 13.5 0.0 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain ThiF PF00899.16 EIE82089.1 - 0.035 13.9 0.1 0.35 10.6 0.1 2.4 2 0 0 2 2 2 0 ThiF family NAD_binding_7 PF13241.1 EIE82089.1 - 0.08 13.2 0.0 0.27 11.5 0.0 1.9 1 0 0 1 1 1 0 Putative NAD(P)-binding Methyltransf_23 PF13489.1 EIE82089.1 - 0.095 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 EIE82089.1 - 0.13 12.8 0.1 0.67 10.5 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain TRAP-delta PF05404.7 EIE82090.1 - 0.016 14.6 0.0 0.023 14.1 0.0 1.4 1 1 0 1 1 1 0 Translocon-associated protein, delta subunit precursor (TRAP-delta) Peptidase_M41 PF01434.13 EIE82091.1 - 3e-76 255.6 2.9 5.2e-76 254.8 2.0 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EIE82091.1 - 8.9e-43 145.6 0.0 2.6e-42 144.1 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EIE82091.1 - 1e-06 28.9 0.2 0.015 15.4 0.0 3.8 3 1 0 4 4 3 1 AAA domain AAA_5 PF07728.9 EIE82091.1 - 3.6e-06 26.7 0.0 8.9e-06 25.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 EIE82091.1 - 1.2e-05 24.1 0.1 3.7e-05 22.6 0.0 1.8 2 0 0 2 2 2 1 TIP49 C-terminus AAA_17 PF13207.1 EIE82091.1 - 1.3e-05 25.9 0.0 5.8e-05 23.8 0.0 2.2 2 1 0 2 2 1 1 AAA domain AAA_19 PF13245.1 EIE82091.1 - 6.6e-05 22.5 0.1 0.00026 20.6 0.0 2.1 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 EIE82091.1 - 0.00013 21.9 1.4 0.0013 18.7 0.2 2.9 2 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 EIE82091.1 - 0.00013 21.0 0.0 0.00044 19.3 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 EIE82091.1 - 0.00019 21.3 0.1 0.0022 17.9 0.0 2.7 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 EIE82091.1 - 0.0012 18.7 0.0 0.012 15.5 0.0 2.5 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.12 EIE82091.1 - 0.0019 17.6 0.1 0.0048 16.3 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.1 EIE82091.1 - 0.0025 17.2 1.5 0.16 11.3 0.2 2.9 2 1 1 3 3 2 1 AAA domain DUF815 PF05673.8 EIE82091.1 - 0.0027 16.6 0.0 0.0062 15.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_28 PF13521.1 EIE82091.1 - 0.0077 16.2 0.0 0.022 14.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EIE82091.1 - 0.011 16.0 0.0 0.042 14.1 0.0 2.2 2 0 0 2 2 1 0 AAA domain Mg_chelatase PF01078.16 EIE82091.1 - 0.015 14.5 0.2 0.043 12.9 0.2 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 EIE82091.1 - 0.015 14.4 0.5 0.036 13.1 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.1 EIE82091.1 - 0.021 14.7 0.0 0.065 13.1 0.0 2.0 1 1 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 EIE82091.1 - 0.026 14.5 0.1 0.17 11.9 0.0 2.4 3 0 0 3 3 2 0 Sigma-54 interaction domain Sigma54_activat PF00158.21 EIE82091.1 - 0.03 13.7 0.4 0.29 10.6 0.0 2.7 4 0 0 4 4 3 0 Sigma-54 interaction domain KaiC PF06745.8 EIE82091.1 - 0.043 12.9 3.1 0.33 10.0 0.0 3.3 4 0 0 4 4 4 0 KaiC NACHT PF05729.7 EIE82091.1 - 0.22 11.1 1.1 0.89 9.1 0.0 2.3 3 0 0 3 3 2 0 NACHT domain Spore_II_R PF09551.5 EIE82091.1 - 0.29 11.1 1.8 16 5.5 0.5 2.6 2 0 0 2 2 2 0 Stage II sporulation protein R (spore_II_R) ABC_tran PF00005.22 EIE82091.1 - 0.53 10.5 2.7 3.3 8.0 0.1 3.2 4 0 0 4 4 3 0 ABC transporter ERK-JNK_inhib PF15002.1 EIE82092.1 - 0.021 14.1 0.0 0.025 13.9 0.0 1.0 1 0 0 1 1 1 0 ERK and JNK pathways, inhibitor DUF883 PF05957.8 EIE82093.1 - 0.0066 16.8 10.4 0.036 14.4 1.7 2.5 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF883) YtxH PF12732.2 EIE82093.1 - 0.036 14.4 17.1 1.3e+02 3.0 11.8 2.6 1 1 0 1 1 1 0 YtxH-like protein DUF1664 PF07889.7 EIE82093.1 - 0.19 11.5 4.9 1.9 8.2 3.4 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Perilipin PF03036.11 EIE82093.1 - 0.88 8.3 5.2 2.4 6.8 0.9 2.1 1 1 1 2 2 2 0 Perilipin family Atg14 PF10186.4 EIE82093.1 - 0.97 8.3 4.5 1.3 7.9 3.1 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF2959 PF11172.3 EIE82093.1 - 2 8.1 7.5 2.7 7.7 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2959) Vfa1 PF08432.5 EIE82093.1 - 5.7 6.9 11.8 9.7 6.1 8.2 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 HATPase_c PF02518.21 EIE82094.1 - 8.9e-25 86.5 0.2 1.8e-24 85.5 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EIE82094.1 - 5.8e-21 74.2 0.1 1.6e-20 72.8 0.1 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.1 EIE82094.1 - 4.8e-19 68.6 0.0 5e-12 46.1 0.0 2.9 3 0 0 3 3 3 2 PAS domain PAS_3 PF08447.6 EIE82094.1 - 4.4e-18 65.1 0.2 9.7e-12 44.8 0.1 2.5 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.5 EIE82094.1 - 4.5e-16 58.8 0.0 1.7e-09 37.6 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS PF00989.19 EIE82094.1 - 1.8e-12 47.0 0.0 5.4e-07 29.3 0.0 2.7 2 0 0 2 2 2 2 PAS fold PAS_8 PF13188.1 EIE82094.1 - 0.0046 16.7 0.0 0.03 14.1 0.0 2.3 2 0 0 2 2 2 1 PAS domain PsbX PF06596.6 EIE82095.1 - 6.2 6.5 10.7 28 4.5 7.4 1.8 1 1 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) PsaN PF05479.6 EIE82095.1 - 7.8 6.4 6.4 7.4 6.5 4.4 1.0 1 0 0 1 1 1 0 Photosystem I reaction centre subunit N (PSAN or PSI-N) KH_1 PF00013.24 EIE82096.1 - 2.3e-41 139.2 4.0 2.5e-14 52.6 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EIE82096.1 - 2.6e-30 103.5 5.3 5.7e-10 38.6 0.2 3.5 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 EIE82096.1 - 5.1e-13 48.3 0.9 0.0018 17.8 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 EIE82096.1 - 8.9e-07 28.4 3.4 0.72 9.5 0.0 3.8 3 0 0 3 3 3 3 KH domain PPV_E2_C PF00511.12 EIE82097.1 - 0.069 13.1 0.0 0.77 9.7 0.0 2.0 2 0 0 2 2 2 0 E2 (early) protein, C terminal DUF1840 PF08895.6 EIE82097.1 - 0.087 12.8 0.0 0.1 12.6 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) DUF2661 PF10860.3 EIE82098.1 - 0.073 13.2 0.1 0.092 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2661) SPAN PF02510.9 EIE82098.1 - 0.51 9.3 2.3 0.58 9.1 1.6 1.1 1 0 0 1 1 1 0 Surface presentation of antigens protein DDE_3 PF13358.1 EIE82101.1 - 2.9e-06 27.1 0.0 7.2e-06 25.8 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease BBIP10 PF14777.1 EIE82102.1 - 0.35 10.2 1.9 1.2 8.5 0.0 2.5 3 0 0 3 3 3 0 Cilia BBSome complex subunit 10 SET PF00856.23 EIE82103.1 - 1.1e-09 38.8 0.0 1.5e-09 38.3 0.0 1.2 1 0 0 1 1 1 1 SET domain HARE-HTH PF05066.8 EIE82104.1 - 0.0002 21.6 0.0 0.00066 19.9 0.0 1.9 1 0 0 1 1 1 1 HB1, ASXL, restriction endonuclease HTH domain zf-Tim10_DDP PF02953.10 EIE82105.1 - 1.4e-16 59.5 0.7 1.8e-16 59.1 0.5 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Cyclin PF08613.6 EIE82106.1 - 9.8e-35 120.1 0.3 1.8e-34 119.3 0.2 1.5 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EIE82106.1 - 2.1e-08 33.7 0.5 4.9e-08 32.5 0.2 1.7 1 1 0 1 1 1 1 Cyclin, N-terminal domain WGG PF10273.4 EIE82106.1 - 0.0079 16.2 0.2 0.018 15.1 0.1 1.6 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 HTH_29 PF13551.1 EIE82107.1 - 4.9e-10 39.5 0.0 3.7e-09 36.7 0.0 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.1 EIE82107.1 - 2e-07 31.7 0.1 9e-07 29.6 0.0 2.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_23 PF13384.1 EIE82107.1 - 5.2e-07 29.1 0.8 2.5e-05 23.7 0.0 2.8 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.1 EIE82107.1 - 9.6e-07 28.7 1.4 2.4e-05 24.2 0.0 2.9 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_Tnp_1 PF01527.15 EIE82107.1 - 0.00013 21.8 1.2 0.00046 20.0 0.1 2.1 2 0 0 2 2 2 1 Transposase HTH_17 PF12728.2 EIE82107.1 - 0.00076 19.6 0.2 0.13 12.5 0.0 2.5 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.1 EIE82107.1 - 0.0016 17.5 0.1 0.0031 16.6 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_30 PF13556.1 EIE82107.1 - 0.0033 16.9 0.4 0.011 15.3 0.1 2.0 2 0 0 2 2 2 1 PucR C-terminal helix-turn-helix domain DUF1804 PF08822.6 EIE82107.1 - 0.04 13.6 0.1 0.13 11.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1804) Terminase_5 PF06056.7 EIE82107.1 - 0.058 12.9 0.6 0.28 10.7 0.0 2.3 2 1 1 3 3 3 0 Putative ATPase subunit of terminase (gpP-like) BPL_N PF09825.4 EIE82107.1 - 0.068 11.9 0.0 0.089 11.5 0.0 1.3 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal DUF746 PF05344.6 EIE82107.1 - 0.14 11.6 0.0 0.31 10.6 0.0 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF746) DDE_3 PF13358.1 EIE82108.1 - 5.8e-18 65.0 1.2 8.9e-18 64.4 0.2 1.8 1 1 2 3 3 3 1 DDE superfamily endonuclease rve PF00665.21 EIE82108.1 - 0.0014 18.7 0.0 0.002 18.2 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain DDE_3 PF13358.1 EIE82110.1 - 2.4e-26 92.2 0.0 8.6e-26 90.4 0.0 2.0 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 EIE82110.1 - 1.9e-09 37.6 0.0 1.1e-08 35.1 0.0 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.1 EIE82110.1 - 5e-07 30.4 0.1 2.4e-06 28.2 0.0 2.3 3 0 0 3 3 1 1 Homeodomain-like domain HTH_23 PF13384.1 EIE82110.1 - 2.9e-06 26.7 1.2 5.7e-05 22.6 0.0 2.8 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.1 EIE82110.1 - 3.2e-05 23.8 4.6 5.7e-05 23.0 0.0 3.1 4 0 0 4 4 4 1 Helix-turn-helix domain HTH_Tnp_1 PF01527.15 EIE82110.1 - 0.0005 19.9 1.2 0.0011 18.8 0.1 2.0 2 0 0 2 2 2 1 Transposase HTH_17 PF12728.2 EIE82110.1 - 0.0026 17.9 0.0 0.28 11.4 0.0 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.1 EIE82110.1 - 0.0032 16.5 0.1 0.0064 15.6 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 rve PF00665.21 EIE82110.1 - 0.0039 17.2 0.0 0.015 15.4 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain HTH_30 PF13556.1 EIE82110.1 - 0.0088 15.6 0.4 0.023 14.3 0.1 1.8 2 0 0 2 2 2 1 PucR C-terminal helix-turn-helix domain Thioredoxin_2 PF13098.1 EIE82110.1 - 0.097 12.8 0.1 0.63 10.2 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin-like domain DUF1804 PF08822.6 EIE82110.1 - 0.11 12.2 0.0 0.3 10.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1804) Hydrolase_like PF13242.1 EIE82111.1 - 7.6e-13 47.9 0.0 1.5e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.1 EIE82111.1 - 2.8e-11 43.2 0.0 5.1e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EIE82111.1 - 2.8e-07 30.9 0.0 0.00016 21.9 0.0 2.4 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EIE82111.1 - 0.00033 21.1 0.0 0.0068 16.8 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.5 EIE82111.1 - 0.0032 16.8 0.0 0.18 11.1 0.0 2.2 2 0 0 2 2 2 1 Mitochondrial PGP phosphatase DUF2599 PF10783.4 EIE82111.1 - 0.085 13.5 0.0 0.28 11.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2599) Macoilin PF09726.4 EIE82112.1 - 3.2 5.9 7.3 3.6 5.7 5.1 1.0 1 0 0 1 1 1 0 Transmembrane protein Arrestin_C PF02752.17 EIE82113.1 - 7.8e-05 22.8 0.2 8.9e-05 22.6 0.1 1.1 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Pkinase PF00069.20 EIE82114.1 - 5.2e-42 143.8 0.0 5.6e-37 127.2 0.0 2.5 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIE82114.1 - 8.6e-16 57.7 0.0 1.6e-13 50.3 0.0 2.4 1 1 1 2 2 2 2 Protein tyrosine kinase PAS_9 PF13426.1 EIE82114.1 - 1e-13 51.5 0.0 0.00038 20.7 0.0 3.8 3 1 0 3 3 3 3 PAS domain PAS PF00989.19 EIE82114.1 - 1.6e-09 37.4 0.0 0.00022 20.9 0.0 4.2 4 0 0 4 4 4 2 PAS fold Kinase-like PF14531.1 EIE82114.1 - 0.00011 21.3 0.0 0.00022 20.2 0.0 1.5 1 1 0 1 1 1 1 Kinase-like PAS_4 PF08448.5 EIE82114.1 - 0.00031 20.7 0.0 0.01 15.8 0.0 2.8 3 0 0 3 3 3 1 PAS fold APH PF01636.18 EIE82114.1 - 0.0016 18.1 0.0 0.0028 17.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family PAS_7 PF12860.2 EIE82114.1 - 0.0046 16.9 0.0 0.7 9.9 0.0 3.4 3 0 0 3 3 3 1 PAS fold PAS_8 PF13188.1 EIE82114.1 - 0.0066 16.2 0.0 0.84 9.5 0.0 3.1 3 0 0 3 3 3 1 PAS domain Kdo PF06293.9 EIE82114.1 - 0.029 13.4 0.1 0.062 12.3 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EIE82114.1 - 0.048 13.0 0.2 0.14 11.5 0.0 1.8 2 0 0 2 2 2 0 RIO1 family Polysacc_deac_1 PF01522.16 EIE82115.1 - 1e-27 96.2 0.0 1.4e-27 95.7 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 EIE82115.1 - 1.9e-09 36.9 0.1 3.5e-09 36.0 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 57 DUF2334 PF10096.4 EIE82115.1 - 0.03 13.7 0.2 0.038 13.4 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) DUF1847 PF08901.6 EIE82115.1 - 0.085 12.3 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1847) RXT2_N PF08595.6 EIE82115.1 - 0.17 11.7 3.0 1.3 8.8 0.1 2.2 2 0 0 2 2 2 0 RXT2-like, N-terminal DUF1870 PF08965.5 EIE82116.1 - 0.0074 15.9 0.8 0.0074 15.9 0.5 2.4 2 1 1 3 3 3 1 Domain of unknown function (DUF1870) HALZ PF02183.13 EIE82116.1 - 0.013 15.1 1.3 0.013 15.1 0.9 6.3 5 1 1 6 6 6 0 Homeobox associated leucine zipper Viral_P18 PF04521.8 EIE82116.1 - 0.016 14.6 2.2 0.016 14.6 1.5 4.4 3 2 2 5 5 5 0 ssRNA positive strand viral 18kD cysteine rich protein DivIC PF04977.10 EIE82116.1 - 0.035 13.5 0.6 0.035 13.5 0.4 6.7 3 2 2 6 6 6 0 Septum formation initiator EphA2_TM PF14575.1 EIE82117.1 - 0.35 11.2 2.2 4.3 7.8 0.2 3.0 3 1 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain DNA_repr_REX1B PF14966.1 EIE82118.1 - 2.5e-05 24.5 4.1 3.4e-05 24.1 2.8 1.2 1 0 0 1 1 1 1 DNA repair REX1-B SpecificRecomb PF10136.4 EIE82118.1 - 0.064 11.2 1.3 0.071 11.1 0.9 1.0 1 0 0 1 1 1 0 Site-specific recombinase Ku_C PF03730.9 EIE82118.1 - 0.48 10.9 6.4 0.39 11.2 2.5 1.9 2 0 0 2 2 2 0 Ku70/Ku80 C-terminal arm Snapin_Pallidin PF14712.1 EIE82118.1 - 4.1 7.7 7.9 0.57 10.5 1.8 2.0 2 0 0 2 2 2 0 Snapin/Pallidin Thioredoxin PF00085.15 EIE82119.1 - 4.4e-12 45.6 0.1 3.3e-11 42.7 0.1 2.3 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EIE82119.1 - 0.041 13.9 0.1 0.67 10.1 0.1 2.2 1 1 1 2 2 2 0 Thioredoxin-like Ribosomal_S2 PF00318.15 EIE82120.1 - 7.4e-43 146.2 0.3 2.6e-22 79.0 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 TRM13 PF05206.9 EIE82121.1 - 7.4e-84 281.0 3.6 9.9e-84 280.6 2.5 1.2 1 0 0 1 1 1 1 Methyltransferase TRM13 zf-U11-48K PF05253.7 EIE82121.1 - 9.5e-09 34.7 1.1 2.1e-08 33.7 0.8 1.6 1 0 0 1 1 1 1 U11-48K-like CHHC zinc finger Methyltransf_32 PF13679.1 EIE82121.1 - 0.0039 16.8 4.2 0.012 15.3 2.8 2.0 1 1 0 1 1 1 1 Methyltransferase domain CAF1-p150_N PF15557.1 EIE82121.1 - 0.026 13.8 0.1 0.055 12.7 0.0 1.5 1 0 0 1 1 1 0 CAF1 complex subunit p150, region binding to PCNA zf-TRAF PF02176.13 EIE82121.1 - 0.44 10.9 7.7 0.12 12.7 1.2 2.9 2 1 1 3 3 3 0 TRAF-type zinc finger DEAD PF00270.24 EIE82122.1 - 4.2e-45 153.2 0.0 1.4e-44 151.5 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIE82122.1 - 1.8e-25 88.6 0.0 4.4e-25 87.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIE82122.1 - 0.0022 17.8 0.0 0.015 15.1 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DAO PF01266.19 EIE82123.1 - 9.4e-19 67.5 0.0 8.7e-10 38.0 0.0 2.3 1 1 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIE82123.1 - 0.00093 19.1 0.1 0.0027 17.6 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EIE82123.1 - 0.012 15.6 0.0 0.049 13.6 0.0 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Ldh_1_N PF00056.18 EIE82123.1 - 0.014 15.2 0.1 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Pyr_redox PF00070.22 EIE82123.1 - 0.016 15.6 0.6 0.037 14.4 0.4 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EIE82123.1 - 0.022 14.6 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EIE82123.1 - 0.024 13.6 0.0 0.033 13.2 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain TrkA_N PF02254.13 EIE82123.1 - 0.064 13.2 0.8 0.18 11.8 0.6 1.7 2 0 0 2 2 2 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.9 EIE82123.1 - 0.17 11.2 0.6 0.36 10.1 0.4 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Polysacc_deac_1 PF01522.16 EIE82124.1 - 4.4e-11 42.4 0.3 9.7e-11 41.3 0.1 1.7 2 0 0 2 2 2 1 Polysaccharide deacetylase muHD PF10291.4 EIE82124.1 - 0.028 13.5 0.0 0.065 12.4 0.0 1.5 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain YtxC PF08812.6 EIE82124.1 - 0.032 13.7 0.1 0.069 12.6 0.0 1.5 1 0 0 1 1 1 0 YtxC-like family p450 PF00067.17 EIE82125.1 - 2.9e-74 250.2 0.1 9.7e-73 245.2 0.1 2.0 1 1 0 1 1 1 1 Cytochrome P450 PI3_PI4_kinase PF00454.22 EIE82128.1 - 1.8e-48 165.1 0.2 3.8e-48 163.9 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 EIE82128.1 - 1.1e-27 97.0 10.5 2.3e-27 95.9 7.3 1.6 1 0 0 1 1 1 1 FAT domain UME PF08064.8 EIE82128.1 - 6.3e-09 35.7 0.3 6.3e-09 35.7 0.2 3.4 3 0 0 3 3 3 1 UME (NUC010) domain FATC PF02260.15 EIE82128.1 - 1.5e-08 33.8 0.0 7.1e-08 31.7 0.0 2.1 2 0 0 2 2 2 1 FATC domain DUF2404 PF10296.4 EIE82129.1 - 3.8e-22 78.2 0.0 6.1e-22 77.5 0.0 1.3 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) Beta_elim_lyase PF01212.16 EIE82130.1 - 1.9e-69 233.9 0.0 2.8e-69 233.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 EIE82130.1 - 2.4e-07 30.0 0.0 5.5e-07 28.8 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EIE82130.1 - 0.0014 17.4 0.0 0.0022 16.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EIE82130.1 - 0.023 13.7 0.0 0.042 12.8 0.0 1.5 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Septin PF00735.13 EIE82130.1 - 0.084 11.8 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Septin MFS_1 PF07690.11 EIE82132.1 - 2.5e-39 135.0 81.3 1.2e-30 106.4 37.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIE82132.1 - 2.8e-06 26.2 17.3 2.8e-06 26.2 12.0 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.2 EIE82132.1 - 0.0019 17.9 2.0 0.0068 16.1 0.5 2.7 2 0 0 2 2 2 1 MFS_1 like family DUF2614 PF11023.3 EIE82132.1 - 2.2 8.0 11.3 1.2 8.8 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2614) HTH_Tnp_Tc3_2 PF01498.13 EIE82133.1 - 0.0034 17.4 0.7 0.0047 16.9 0.5 1.2 1 0 0 1 1 1 1 Transposase RhoGEF PF00621.15 EIE82134.1 - 2e-42 145.0 2.6 3.5e-42 144.3 1.8 1.4 1 0 0 1 1 1 1 RhoGEF domain PH_10 PF15411.1 EIE82134.1 - 3.9e-31 107.6 1.4 8.4e-31 106.5 1.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain CDC24 PF06395.6 EIE82134.1 - 2.2e-30 104.5 0.2 5.7e-30 103.2 0.1 1.7 1 0 0 1 1 1 1 CDC24 Calponin PB1 PF00564.19 EIE82134.1 - 3.7e-14 52.1 0.0 1.1e-13 50.6 0.0 1.9 1 0 0 1 1 1 1 PB1 domain PH PF00169.24 EIE82134.1 - 0.00043 20.4 1.4 0.0012 19.0 1.0 1.8 1 0 0 1 1 1 1 PH domain CH PF00307.26 EIE82134.1 - 0.0022 18.0 1.7 0.0097 15.9 0.2 2.6 2 0 0 2 2 2 1 Calponin homology (CH) domain SMN PF06003.7 EIE82134.1 - 0.034 13.2 4.2 0.067 12.2 2.9 1.4 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Ribosomal_S17 PF00366.15 EIE82135.1 - 1.2e-29 102.1 1.3 1.9e-29 101.5 0.9 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 CDC48_2 PF02933.12 EIE82135.1 - 0.0022 17.6 0.2 0.0055 16.3 0.0 1.7 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AATF-Che1 PF13339.1 EIE82136.1 - 0.016 15.3 1.7 0.022 14.8 1.2 1.2 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor GAS2 PF02187.12 EIE82137.1 - 7.7e-09 35.2 0.1 3e-08 33.3 0.0 2.1 2 0 0 2 2 2 1 Growth-Arrest-Specific Protein 2 Domain NAD_binding_1 PF00175.16 EIE82137.1 - 5.4 7.6 10.7 1.2 9.7 0.0 4.8 4 0 0 4 4 4 0 Oxidoreductase NAD-binding domain Lactamase_B PF00753.22 EIE82138.1 - 2e-16 60.2 0.1 2.4e-16 59.9 0.1 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.1 EIE82138.1 - 1.2e-05 25.0 0.0 1.5e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.2 EIE82138.1 - 0.00041 19.9 0.3 0.00068 19.2 0.2 1.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Gag_p30 PF02093.11 EIE82139.1 - 0.0074 15.5 0.1 0.0091 15.2 0.0 1.1 1 0 0 1 1 1 1 Gag P30 core shell protein Arginase PF00491.16 EIE82140.1 - 2.5e-69 233.6 0.1 2.9e-69 233.4 0.1 1.0 1 0 0 1 1 1 1 Arginase family DUF1057 PF06342.7 EIE82140.1 - 0.086 11.6 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Velvet PF11754.3 EIE82142.1 - 9.6e-13 48.1 0.5 1.2e-11 44.6 0.3 2.6 1 1 0 1 1 1 1 Velvet factor RVT_1 PF00078.22 EIE82143.1 - 1.3e-35 122.7 0.0 2.4e-35 121.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.1 EIE82143.1 - 0.00033 20.8 1.7 0.00097 19.4 1.2 1.8 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Exo_endo_phos_2 PF14529.1 EIE82143.1 - 0.033 13.7 0.1 0.033 13.7 0.1 2.5 3 0 0 3 3 3 0 Endonuclease-reverse transcriptase DUF4106 PF13388.1 EIE82143.1 - 0.32 9.9 0.1 0.5 9.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Mucin PF01456.12 EIE82144.1 - 1.5 8.5 16.3 0.48 10.1 1.9 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein BAG PF02179.11 EIE82145.1 - 5.5e-09 36.0 0.7 5.5e-09 36.0 0.5 2.5 3 0 0 3 3 3 1 BAG domain Gyro_capsid PF04162.7 EIE82145.1 - 1.1 7.4 5.5 1.6 6.9 3.8 1.2 1 0 0 1 1 1 0 Gyrovirus capsid protein (VP1) DUF4047 PF13256.1 EIE82146.1 - 0.012 15.5 0.6 0.014 15.3 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) Sds3 PF08598.6 EIE82146.1 - 2.3 7.7 5.0 12 5.3 3.5 1.9 1 1 0 1 1 1 0 Sds3-like WD40 PF00400.27 EIE82147.1 - 2.4e-39 131.8 16.9 1.9e-10 40.2 0.0 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 EIE82147.1 - 3.2e-05 23.7 0.2 0.036 13.7 0.2 2.8 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 EIE82147.1 - 0.02 13.6 1.0 5.1 5.7 0.3 2.8 1 1 2 3 3 3 0 Nup133 N terminal like PP2C PF00481.16 EIE82148.1 - 2.1e-80 269.8 0.1 2.6e-80 269.4 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C TBX PF12598.3 EIE82148.1 - 0.061 13.7 5.2 1.3 9.4 3.8 2.4 2 0 0 2 2 2 0 T-box transcription factor Gti1_Pac2 PF09729.4 EIE82149.1 - 6.3e-22 78.2 3.4 6.8e-13 48.8 0.4 2.2 1 1 1 2 2 2 2 Gti1/Pac2 family Ceramidase PF05875.7 EIE82150.1 - 4.5e-29 101.3 17.8 7.7e-29 100.6 12.3 1.4 1 1 0 1 1 1 1 Ceramidase PP2C PF00481.16 EIE82151.1 - 1.8e-39 135.6 0.0 2.5e-39 135.2 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 EIE82152.1 - 0.011 15.1 0.0 0.012 14.9 0.0 1.0 1 0 0 1 1 1 0 Protein phosphatase 2C DUF3488 PF11992.3 EIE82153.1 - 0.00078 18.1 2.9 0.0011 17.7 2.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3488) DPM3 PF08285.6 EIE82153.1 - 0.17 11.7 0.2 0.17 11.7 0.2 2.8 1 1 2 3 3 3 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) PPR_2 PF13041.1 EIE82154.1 - 5.2e-34 115.9 5.3 1.7e-11 43.8 0.7 6.3 3 2 3 6 6 6 5 PPR repeat family PPR_3 PF13812.1 EIE82154.1 - 7e-27 91.4 0.0 2.8e-05 24.0 0.0 7.3 8 0 0 8 8 8 5 Pentatricopeptide repeat domain PPR PF01535.15 EIE82154.1 - 1.3e-26 90.7 1.3 1.4e-05 24.7 0.0 7.0 7 0 0 7 7 7 4 PPR repeat PPR_1 PF12854.2 EIE82154.1 - 3e-20 71.3 0.0 4.8e-07 29.1 0.0 6.8 7 0 0 7 7 7 2 PPR repeat ECSIT PF06239.6 EIE82154.1 - 7.8e-05 21.6 0.4 0.35 9.7 0.0 3.3 2 1 0 2 2 2 2 Evolutionarily conserved signalling intermediate in Toll pathway ATP13 PF12921.2 EIE82154.1 - 0.028 13.7 0.0 3.5 7.0 0.0 3.1 2 1 1 3 3 3 0 Mitochondrial ATPase expression DUF3366 PF11846.3 EIE82154.1 - 0.058 13.2 0.0 7.4 6.4 0.0 3.0 1 1 1 3 3 3 0 Domain of unknown function (DUF3366) Clr5 PF14420.1 EIE82154.1 - 0.1 12.5 0.5 0.52 10.2 0.0 2.4 3 0 0 3 3 3 0 Clr5 domain DUF262 PF03235.9 EIE82154.1 - 0.46 10.4 5.8 0.33 10.8 1.7 2.3 1 1 2 3 3 3 0 Protein of unknown function DUF262 Ricin_B_lectin PF00652.17 EIE82155.1 - 0.0086 16.1 0.3 0.01 15.8 0.2 1.1 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 EIE82155.1 - 0.014 15.7 0.2 0.018 15.4 0.2 1.1 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain-like DUF2621 PF11084.3 EIE82155.1 - 0.43 10.2 4.6 0.5 10.0 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2621) DUF1443 PF07280.6 EIE82155.1 - 4.7 6.8 5.6 21 4.7 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1443) Pkinase PF00069.20 EIE82156.1 - 0.058 12.5 0.0 0.058 12.5 0.0 1.0 1 0 0 1 1 1 0 Protein kinase domain NMT_C PF02799.10 EIE82157.1 - 5.3e-79 264.0 2.0 5.5e-79 263.9 0.5 1.6 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.14 EIE82157.1 - 1.4e-75 252.3 0.1 2.8e-75 251.4 0.0 1.5 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.1 EIE82157.1 - 0.027 14.3 0.1 0.078 12.8 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EIE82157.1 - 0.039 14.1 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Rotamase PF00639.16 EIE82157.1 - 0.28 11.9 1.7 0.71 10.6 1.2 1.7 1 0 0 1 1 1 0 PPIC-type PPIASE domain IucA_IucC PF04183.7 EIE82159.1 - 1.1e-18 67.4 0.0 2e-18 66.6 0.0 1.4 1 1 0 1 1 1 1 IucA / IucC family FhuF PF06276.7 EIE82159.1 - 2.9e-14 53.3 0.0 5.3e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 Ferric iron reductase FhuF-like transporter DUF1404 PF07185.6 EIE82160.1 - 0.019 14.5 0.0 0.022 14.3 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1404) Trp_oprn_chp PF09534.5 EIE82160.1 - 0.55 9.8 5.6 9.4 5.7 3.9 2.0 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Asp PF00026.18 EIE82161.1 - 2e-109 365.7 1.1 2.4e-109 365.4 0.7 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIE82161.1 - 1.5e-07 31.5 0.1 5.7e-07 29.6 0.0 1.9 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EIE82161.1 - 6.3e-06 25.8 0.1 6.8e-05 22.4 0.0 2.4 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 EIE82161.1 - 0.016 15.7 0.2 1.9 9.0 0.0 2.9 2 1 0 2 2 2 0 Aspartyl protease Adeno_E3 PF06040.6 EIE82161.1 - 0.036 14.0 0.0 0.15 11.9 0.0 2.1 3 0 0 3 3 3 0 Adenovirus E3 protein SNF2_N PF00176.18 EIE82162.1 - 7.2e-11 41.4 0.5 7.2e-11 41.4 0.3 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EIE82163.1 - 2.9e-05 23.8 0.1 5.7e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Carboxyl_trans PF01039.17 EIE82164.1 - 4.5e-109 365.0 0.9 6.2e-62 209.5 0.0 2.0 1 1 1 2 2 2 2 Carboxyl transferase domain DUF1212 PF06738.7 EIE82165.1 - 2.2e-34 118.6 13.7 3.6e-30 104.8 0.2 2.5 2 1 0 2 2 2 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 EIE82165.1 - 7.7e-13 48.5 26.7 7.7e-13 48.5 9.8 2.6 2 1 0 2 2 2 2 Protein of unknown function (DUF3815) CheC PF04509.7 EIE82165.1 - 0.48 10.2 5.4 0.1 12.3 0.5 2.2 2 0 0 2 2 2 0 CheC-like family MFS_1 PF07690.11 EIE82166.1 - 3.1e-05 22.8 7.0 0.00056 18.7 4.8 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3825 PF12873.2 EIE82166.1 - 0.11 11.6 0.0 0.18 10.9 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3825) PGG PF13962.1 EIE82166.1 - 0.12 12.0 2.6 0.46 10.1 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function MFS_2 PF13347.1 EIE82166.1 - 0.79 8.0 14.6 10 4.3 10.1 2.6 1 1 0 1 1 1 0 MFS/sugar transport protein Gti1_Pac2 PF09729.4 EIE82167.1 - 3.9e-57 192.7 0.8 3.9e-57 192.7 0.6 3.4 2 2 0 2 2 2 1 Gti1/Pac2 family Cpn60_TCP1 PF00118.19 EIE82168.1 - 1.7e-119 399.5 5.3 2e-119 399.4 3.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family zf-C2H2_4 PF13894.1 EIE82169.1 - 0.00016 21.7 14.4 0.035 14.4 0.5 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EIE82169.1 - 0.0011 19.0 0.7 1.1 9.5 0.0 2.9 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 EIE82169.1 - 0.0095 16.2 7.5 0.037 14.3 0.9 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIE82169.1 - 0.083 13.2 0.7 0.083 13.2 0.5 3.8 4 0 0 4 4 4 0 Zinc-finger double domain CHORD PF04968.7 EIE82169.1 - 0.91 9.8 5.2 0.86 9.9 1.8 2.2 2 0 0 2 2 2 0 CHORD OAF PF14941.1 EIE82169.1 - 1.3 8.1 4.5 1.1 8.3 0.4 2.1 1 1 1 2 2 2 0 Transcriptional regulator, Out at first RasGEF PF00617.14 EIE82170.1 - 3.3e-43 147.6 0.1 6.3e-43 146.6 0.1 1.5 1 0 0 1 1 1 1 RasGEF domain MscS_porin PF12795.2 EIE82170.1 - 0.0047 16.2 0.5 0.011 15.1 0.4 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain PCAF_N PF06466.6 EIE82170.1 - 0.0085 15.4 0.1 0.11 11.8 0.0 2.2 2 0 0 2 2 2 1 PCAF (P300/CBP-associated factor) N-terminal domain MIT PF04212.13 EIE82170.1 - 0.084 12.7 0.4 0.53 10.2 0.0 2.3 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain ATP-gua_Ptrans PF00217.14 EIE82170.1 - 1.8 7.7 5.1 2.1 7.6 0.2 2.6 3 0 0 3 3 3 0 ATP:guanido phosphotransferase, C-terminal catalytic domain 14-3-3 PF00244.15 EIE82171.1 - 1.7e-115 384.0 7.8 2e-115 383.8 5.4 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF837 PF05769.6 EIE82171.1 - 0.45 10.0 4.6 2.5 7.6 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF837) UAF_Rrn10 PF05234.6 EIE82172.1 - 0.0057 16.6 0.1 0.011 15.7 0.1 1.5 1 0 0 1 1 1 1 UAF complex subunit Rrn10 MRC1 PF09444.5 EIE82174.1 - 3.3e-10 40.4 0.3 3.3e-10 40.4 0.2 2.6 2 1 0 2 2 2 1 MRC1-like domain RAP1 PF07218.6 EIE82174.1 - 0.024 12.7 0.7 0.029 12.4 0.5 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) YfhD PF14151.1 EIE82174.1 - 0.041 13.9 1.1 0.16 12.1 0.8 2.0 1 0 0 1 1 1 0 YfhD-like protein AAA PF00004.24 EIE82175.1 - 7.2e-38 129.7 0.0 1.7e-37 128.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EIE82175.1 - 7.8e-08 32.5 0.3 9.6e-05 22.5 0.1 3.3 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.1 EIE82175.1 - 1.3e-06 28.3 0.0 4.3e-06 26.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EIE82175.1 - 2.3e-06 27.3 0.1 1.3e-05 24.9 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EIE82175.1 - 3.8e-06 27.0 0.7 0.00022 21.2 0.0 2.6 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.9 EIE82175.1 - 5.5e-06 26.4 0.0 7.9e-05 22.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 EIE82175.1 - 5.6e-06 25.5 0.0 1.2e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EIE82175.1 - 4.4e-05 24.2 0.0 0.00013 22.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EIE82175.1 - 6.5e-05 22.8 0.0 0.00011 22.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EIE82175.1 - 0.00047 19.3 0.2 0.0013 17.8 0.1 1.7 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 EIE82175.1 - 0.00049 19.5 0.0 0.00084 18.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 EIE82175.1 - 0.00049 19.2 0.0 0.00086 18.4 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_25 PF13481.1 EIE82175.1 - 0.00062 19.2 0.3 0.026 13.9 0.2 2.2 1 1 1 2 2 2 1 AAA domain RNA_helicase PF00910.17 EIE82175.1 - 0.00087 19.4 0.0 0.0018 18.4 0.0 1.6 1 1 0 1 1 1 1 RNA helicase AAA_28 PF13521.1 EIE82175.1 - 0.0012 18.8 0.0 0.0024 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EIE82175.1 - 0.0014 18.3 0.0 0.0085 15.7 0.0 2.2 1 1 1 2 2 2 1 NACHT domain AAA_18 PF13238.1 EIE82175.1 - 0.0016 18.7 0.0 0.0039 17.4 0.0 1.8 2 0 0 2 2 1 1 AAA domain ABC_tran PF00005.22 EIE82175.1 - 0.0021 18.3 0.0 0.005 17.1 0.0 1.7 1 1 0 1 1 1 1 ABC transporter Sigma54_activ_2 PF14532.1 EIE82175.1 - 0.0028 17.6 0.0 0.0064 16.5 0.0 1.7 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_24 PF13479.1 EIE82175.1 - 0.0056 16.2 0.1 0.012 15.2 0.1 1.6 1 1 0 1 1 1 1 AAA domain Guanylate_kin PF00625.16 EIE82175.1 - 0.0057 16.1 0.1 0.11 11.9 0.0 2.8 2 1 1 3 3 3 1 Guanylate kinase TIP49 PF06068.8 EIE82175.1 - 0.0069 15.1 0.0 0.012 14.4 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_10 PF12846.2 EIE82175.1 - 0.0086 15.5 0.1 1.1 8.6 0.0 2.6 1 1 1 2 2 2 1 AAA-like domain Bac_DnaA PF00308.13 EIE82175.1 - 0.0092 15.6 0.0 0.018 14.7 0.0 1.4 1 1 0 1 1 1 1 Bacterial dnaA protein Viral_helicase1 PF01443.13 EIE82175.1 - 0.012 15.1 0.0 0.021 14.3 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF815 PF05673.8 EIE82175.1 - 0.013 14.4 0.0 0.021 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Arch_ATPase PF01637.13 EIE82175.1 - 0.013 15.1 0.0 0.07 12.8 0.0 1.9 1 1 1 2 2 2 0 Archaeal ATPase UPF0079 PF02367.12 EIE82175.1 - 0.014 14.9 0.1 0.11 12.1 0.0 2.2 2 1 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Rad17 PF03215.10 EIE82175.1 - 0.016 13.9 0.0 0.025 13.2 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein KaiC PF06745.8 EIE82175.1 - 0.02 14.0 0.0 0.36 9.9 0.0 2.3 1 1 1 2 2 2 0 KaiC AAA_19 PF13245.1 EIE82175.1 - 0.02 14.6 0.1 0.05 13.3 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain Sigma54_activat PF00158.21 EIE82175.1 - 0.026 13.9 0.0 0.058 12.8 0.0 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_21 PF13304.1 EIE82175.1 - 0.03 14.2 0.3 7 6.5 0.0 2.5 2 1 1 3 3 2 0 AAA domain AAA_3 PF07726.6 EIE82175.1 - 0.03 13.9 0.0 0.12 11.9 0.0 2.0 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.12 EIE82175.1 - 0.045 12.6 0.0 0.067 12.0 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 tRNA_lig_kinase PF08303.6 EIE82175.1 - 0.071 12.9 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 tRNA ligase kinase domain NB-ARC PF00931.17 EIE82175.1 - 0.1 11.4 0.0 0.18 10.6 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain PhoH PF02562.11 EIE82175.1 - 0.11 11.7 0.2 0.33 10.1 0.1 1.9 1 1 0 1 1 1 0 PhoH-like protein SKI PF01202.17 EIE82175.1 - 0.12 12.2 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Shikimate kinase GTP_EFTU PF00009.22 EIE82176.1 - 1.6e-17 63.5 0.0 2.3e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EIE82176.1 - 6.8e-16 58.2 1.4 2.5e-15 56.4 0.1 2.5 3 0 0 3 3 3 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EIE82176.1 - 3.8e-09 36.5 3.0 9.7e-09 35.2 1.5 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 EIE82176.1 - 0.00032 20.2 0.1 0.00075 19.0 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 4 PduV-EutP PF10662.4 EIE82176.1 - 0.099 12.1 0.1 7.9 5.9 0.1 2.5 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF1641 PF07849.6 EIE82178.1 - 0.037 13.6 0.1 0.098 12.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1641) Tbf5 PF06331.7 EIE82178.1 - 0.05 13.3 0.4 0.098 12.4 0.2 1.5 1 1 0 1 1 1 0 Transcription factor TFIIH complex subunit Tfb5 DUF3484 PF11983.3 EIE82178.1 - 0.59 11.0 5.8 2.6 8.9 4.0 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF3484) DUF3449 PF11931.3 EIE82178.1 - 0.82 9.1 6.1 5.7 6.4 4.2 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF3449) DrrA_P4M PF14860.1 EIE82178.1 - 0.99 9.1 6.4 1.5 8.6 4.0 1.6 1 1 0 1 1 1 0 DrrA phosphatidylinositol 4-phosphate binding domain Gar1 PF04410.9 EIE82179.1 - 2.2e-29 101.9 0.5 2.2e-29 101.9 0.4 2.3 2 1 0 2 2 2 1 Gar1/Naf1 RNA binding region CENP-B_dimeris PF09026.5 EIE82179.1 - 0.09 13.0 5.3 0.18 12.0 3.7 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nop14 PF04147.7 EIE82179.1 - 0.17 9.8 9.2 0.2 9.5 6.4 1.1 1 0 0 1 1 1 0 Nop14-like family Retinal PF15449.1 EIE82179.1 - 3.9 4.9 7.1 5 4.6 4.9 1.0 1 0 0 1 1 1 0 Retinal protein Glyco_hydro_68 PF02435.11 EIE82180.1 - 0.091 11.4 0.0 0.093 11.4 0.0 1.0 1 0 0 1 1 1 0 Levansucrase/Invertase Tyr-DNA_phospho PF06087.7 EIE82181.1 - 1.4e-46 159.1 0.0 2.2e-46 158.4 0.0 1.2 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 EIE82181.1 - 0.026 14.2 0.0 0.19 11.4 0.0 2.1 2 0 0 2 2 2 0 PLD-like domain hDGE_amylase PF14701.1 EIE82182.1 - 2.7e-156 520.7 0.0 3.7e-156 520.2 0.0 1.2 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 EIE82182.1 - 1.1e-117 392.9 0.0 1.6e-117 392.3 0.0 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 EIE82182.1 - 1e-70 237.9 0.0 1.5e-70 237.3 0.0 1.3 1 0 0 1 1 1 1 central domain of human glycogen debranching enzyme hGDE_N PF14699.1 EIE82182.1 - 7.8e-13 48.0 0.0 1.9e-12 46.8 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme DUF4038 PF13204.1 EIE82182.1 - 0.04 13.2 0.0 0.08 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4038) Polysacc_lyase PF14099.1 EIE82183.1 - 3.3e-05 23.6 4.9 4.5e-05 23.2 2.5 1.8 1 1 0 1 1 1 1 Polysaccharide lyase Laminin_G_3 PF13385.1 EIE82183.1 - 0.0044 17.2 0.3 0.0044 17.2 0.2 1.8 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily DUF2208 PF09973.4 EIE82183.1 - 0.1 11.7 0.9 0.21 10.8 0.2 1.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) Myotub-related PF06602.9 EIE82185.1 - 1.9e-117 392.0 6.8 1e-62 212.0 2.9 2.1 1 1 1 2 2 2 2 Myotubularin-like phosphatase domain GRAM PF02893.15 EIE82185.1 - 0.0031 16.9 0.0 0.012 15.1 0.0 2.0 2 0 0 2 2 2 1 GRAM domain Y_phosphatase3 PF13350.1 EIE82185.1 - 0.0042 17.3 0.0 0.014 15.6 0.0 1.9 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 EIE82185.1 - 0.0045 16.3 0.1 0.015 14.6 0.0 1.9 2 0 0 2 2 2 1 Protein-tyrosine phosphatase DSPc PF00782.15 EIE82185.1 - 0.084 12.4 0.2 0.18 11.3 0.2 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Mannosyl_trans PF05007.8 EIE82187.1 - 6.4e-66 222.6 19.2 1.7e-65 221.2 10.8 2.5 2 1 0 2 2 2 1 Mannosyltransferase (PIG-M) WD40 PF00400.27 EIE82188.1 - 1.7e-52 173.5 20.7 8.6e-11 41.2 0.1 8.3 7 1 0 7 7 7 7 WD domain, G-beta repeat F-box PF00646.28 EIE82188.1 - 9.4e-10 37.9 2.2 2e-09 36.8 1.5 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EIE82188.1 - 1.5e-07 31.0 1.6 2.8e-07 30.1 1.1 1.5 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 EIE82188.1 - 3.6e-07 28.7 8.7 0.016 13.3 0.4 5.1 1 1 4 5 5 5 3 Nucleoporin Nup120/160 PQQ_2 PF13360.1 EIE82188.1 - 0.00016 21.2 1.0 0.67 9.3 0.0 3.6 2 1 0 2 2 2 2 PQQ-like domain Nucleoporin_N PF08801.6 EIE82188.1 - 0.00043 19.1 3.2 2.6 6.6 0.2 4.6 1 1 1 3 3 3 2 Nup133 N terminal like MBOAT_2 PF13813.1 EIE82189.1 - 5.6e-08 32.7 0.3 6.4e-08 32.5 0.2 1.1 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family p450 PF00067.17 EIE82190.1 - 9.7e-84 281.5 0.0 1.1e-83 281.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MU117 PF15474.1 EIE82191.1 - 0.048 14.1 0.4 0.069 13.6 0.3 1.3 1 0 0 1 1 1 0 Meiotically up-regulated gene family Glyco_hydro_46 PF01374.13 EIE82192.1 - 4.7e-24 85.1 0.2 5.6e-24 84.8 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 46 Aldo_ket_red PF00248.16 EIE82193.1 - 3e-45 154.2 0.0 3.7e-45 153.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family KilA-N PF04383.8 EIE82194.1 - 0.00024 20.7 0.0 0.00031 20.3 0.0 1.1 1 0 0 1 1 1 1 KilA-N domain Peptidase_C65 PF10275.4 EIE82197.1 - 0.0011 18.4 4.6 0.0089 15.4 0.3 2.5 2 0 0 2 2 2 2 Peptidase C65 Otubain DUF1216 PF06746.6 EIE82197.1 - 0.19 11.5 6.6 0.073 12.8 1.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1216) Ribosomal_S15 PF00312.17 EIE82198.1 - 2.6e-24 84.7 2.3 4.8e-24 83.9 1.6 1.4 1 0 0 1 1 1 1 Ribosomal protein S15 GAS PF13851.1 EIE82198.1 - 0.043 13.0 0.8 0.043 13.0 0.6 2.1 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding DnaI_N PF07319.6 EIE82198.1 - 0.063 13.5 0.9 15 5.8 0.1 2.6 2 0 0 2 2 2 0 Primosomal protein DnaI N-terminus CENP-H PF05837.7 EIE82198.1 - 0.26 11.4 3.9 1.6 8.9 0.1 2.9 3 0 0 3 3 3 0 Centromere protein H (CENP-H) DUF948 PF06103.6 EIE82199.1 - 0.00032 20.5 1.5 0.00048 19.9 1.0 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF948) TMF_TATA_bd PF12325.3 EIE82199.1 - 0.00047 19.8 0.5 0.00057 19.5 0.3 1.1 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding GOLGA2L5 PF15070.1 EIE82199.1 - 0.00093 17.8 3.2 0.0011 17.5 2.2 1.0 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 EzrA PF06160.7 EIE82199.1 - 0.0031 15.7 0.5 0.0036 15.5 0.4 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Herpes_U30 PF04523.8 EIE82199.1 - 0.0031 15.0 0.8 0.0033 14.9 0.6 1.0 1 0 0 1 1 1 1 Herpes virus tegument protein U30 TelA PF05816.6 EIE82199.1 - 0.0044 15.7 0.5 0.0051 15.5 0.3 1.1 1 0 0 1 1 1 1 Toxic anion resistance protein (TelA) Lebercilin PF15619.1 EIE82199.1 - 0.0065 15.9 0.4 0.007 15.8 0.3 1.1 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease Tektin PF03148.9 EIE82199.1 - 0.0074 14.8 1.4 0.009 14.5 1.0 1.1 1 0 0 1 1 1 1 Tektin family Bacillus_HBL PF05791.6 EIE82199.1 - 0.009 15.4 1.8 0.011 15.0 1.3 1.2 1 0 0 1 1 1 1 Bacillus haemolytic enterotoxin (HBL) CENP-F_leu_zip PF10473.4 EIE82199.1 - 0.01 15.7 1.0 0.012 15.4 0.7 1.1 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BLOC1_2 PF10046.4 EIE82199.1 - 0.011 15.8 1.3 0.017 15.2 0.9 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 YlqD PF11068.3 EIE82199.1 - 0.012 15.6 1.8 0.013 15.4 1.3 1.2 1 0 0 1 1 1 0 YlqD protein NAS PF03059.11 EIE82199.1 - 0.013 14.7 0.1 0.014 14.6 0.0 1.1 1 0 0 1 1 1 0 Nicotianamine synthase protein DivIVA PF05103.8 EIE82199.1 - 0.014 15.4 0.4 0.018 15.1 0.3 1.2 1 0 0 1 1 1 0 DivIVA protein IFT57 PF10498.4 EIE82199.1 - 0.021 13.5 1.0 0.022 13.5 0.7 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 AAA_32 PF13654.1 EIE82199.1 - 0.022 13.4 0.1 0.022 13.4 0.1 1.0 1 0 0 1 1 1 0 AAA domain Flagellin_N PF00669.15 EIE82199.1 - 0.024 14.4 0.5 0.036 13.8 0.4 1.2 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region FliJ PF02050.11 EIE82199.1 - 0.027 14.5 2.5 0.042 13.8 1.7 1.4 1 0 0 1 1 1 0 Flagellar FliJ protein TBPIP PF07106.8 EIE82199.1 - 0.039 13.5 1.1 0.049 13.1 0.8 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) V_ATPase_I PF01496.14 EIE82199.1 - 0.041 11.7 0.8 0.041 11.7 0.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3450 PF11932.3 EIE82199.1 - 0.048 12.9 4.8 0.061 12.5 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) GrpE PF01025.14 EIE82199.1 - 0.051 13.1 0.9 0.068 12.7 0.6 1.2 1 0 0 1 1 1 0 GrpE Filament PF00038.16 EIE82199.1 - 0.055 12.9 3.0 0.066 12.6 2.1 1.1 1 0 0 1 1 1 0 Intermediate filament protein tRNA-synt_His PF13393.1 EIE82199.1 - 0.063 12.3 0.2 0.071 12.1 0.1 1.1 1 0 0 1 1 1 0 Histidyl-tRNA synthetase Dak2 PF02734.12 EIE82199.1 - 0.064 12.9 0.1 0.081 12.5 0.0 1.1 1 0 0 1 1 1 0 DAK2 domain Prefoldin PF02996.12 EIE82199.1 - 0.066 12.8 1.6 0.1 12.2 1.1 1.2 1 0 0 1 1 1 0 Prefoldin subunit DUF4201 PF13870.1 EIE82199.1 - 0.068 12.5 2.6 0.083 12.3 1.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) DUF2316 PF10078.4 EIE82199.1 - 0.068 13.1 0.4 0.089 12.7 0.3 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2316) Spc7 PF08317.6 EIE82199.1 - 0.07 11.7 2.0 0.084 11.5 1.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DegS PF05384.6 EIE82199.1 - 0.08 12.1 0.7 0.15 11.2 0.5 1.4 1 1 0 1 1 1 0 Sensor protein DegS Phage_tail_S PF05069.8 EIE82199.1 - 0.082 12.6 0.6 0.1 12.3 0.4 1.2 1 0 0 1 1 1 0 Phage virion morphogenesis family WEMBL PF05701.6 EIE82199.1 - 0.091 11.2 0.4 0.1 11.0 0.3 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light COG2 PF06148.6 EIE82199.1 - 0.097 12.5 0.3 0.13 12.1 0.2 1.2 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF641 PF04859.7 EIE82199.1 - 0.19 11.4 2.2 0.26 11.0 1.5 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) DivIC PF04977.10 EIE82199.1 - 0.24 10.9 3.9 0.66 9.4 2.7 1.7 1 1 0 1 1 1 0 Septum formation initiator DUF1631 PF07793.6 EIE82199.1 - 0.29 9.2 3.6 0.32 9.0 2.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) WXG100 PF06013.7 EIE82199.1 - 0.33 10.9 3.7 0.8 9.7 2.0 1.9 1 1 1 2 2 2 0 Proteins of 100 residues with WXG DUF4175 PF13779.1 EIE82199.1 - 0.44 8.1 5.6 0.45 8.1 3.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) H-kinase_dim PF02895.9 EIE82199.1 - 0.54 10.6 2.8 1.5 9.1 1.9 1.8 1 1 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain SseC PF04888.7 EIE82199.1 - 0.54 9.5 3.5 0.67 9.2 2.4 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Cast PF10174.4 EIE82199.1 - 0.55 8.2 6.0 0.63 8.0 4.1 1.1 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone NPV_P10 PF05531.7 EIE82199.1 - 0.61 10.3 5.1 0.93 9.7 3.5 1.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein NTR2 PF15458.1 EIE82199.1 - 1.5 8.0 5.3 1.8 7.7 3.7 1.2 1 0 0 1 1 1 0 Nineteen complex-related protein 2 Baculo_PEP_C PF04513.7 EIE82199.1 - 1.5 8.6 6.0 2.3 8.0 4.1 1.4 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus ADIP PF11559.3 EIE82199.1 - 2.3 8.0 8.1 3 7.7 5.6 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding UBX PF00789.15 EIE82201.1 - 0.00018 21.4 0.1 0.00043 20.2 0.0 1.7 1 1 0 1 1 1 1 UBX domain BTV_NS2 PF04514.7 EIE82201.1 - 0.0071 15.2 8.6 0.0083 15.0 5.9 1.0 1 0 0 1 1 1 1 Bluetongue virus non-structural protein NS2 ORC3_N PF07034.6 EIE82201.1 - 0.33 9.8 2.4 0.43 9.4 1.7 1.1 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 3 N-terminus Med19 PF10278.4 EIE82201.1 - 1.1 8.9 9.7 1.3 8.6 6.7 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 DDHD PF02862.12 EIE82201.1 - 2 8.1 6.1 2.6 7.7 4.2 1.1 1 0 0 1 1 1 0 DDHD domain PBP_sp32 PF07222.7 EIE82201.1 - 3.4 6.7 15.0 4.4 6.4 10.4 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Borrelia_P83 PF05262.6 EIE82201.1 - 5 5.2 11.8 5.3 5.1 8.2 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein YqfQ PF14181.1 EIE82201.1 - 8.8 6.3 7.3 12 5.9 5.0 1.3 1 0 0 1 1 1 0 YqfQ-like protein PRTP PF01366.13 EIE82201.1 - 9.6 4.0 7.5 12 3.7 5.2 1.0 1 0 0 1 1 1 0 Herpesvirus processing and transport protein LSM PF01423.17 EIE82202.1 - 7.1e-17 60.7 0.7 1.1e-16 60.1 0.5 1.3 1 0 0 1 1 1 1 LSM domain CHCH PF06747.8 EIE82203.1 - 9.8e-10 38.0 2.9 9.8e-10 38.0 2.0 2.5 2 1 0 2 2 2 2 CHCH domain Pet191_N PF10203.4 EIE82203.1 - 0.7 9.9 9.2 0.78 9.8 4.2 2.5 1 1 1 3 3 3 0 Cytochrome c oxidase assembly protein PET191 Colipase-like PF15083.1 EIE82203.1 - 1.5 8.7 7.3 2.4 8.1 4.3 1.7 1 1 0 1 1 1 0 Colipase-like Cmc1 PF08583.5 EIE82203.1 - 8.7 6.2 12.2 3.1 7.6 1.8 2.5 1 1 2 3 3 3 0 Cytochrome c oxidase biogenesis protein Cmc1 like COX6B PF02297.12 EIE82203.1 - 8.9 6.4 11.2 4.7e+02 0.8 7.8 2.2 1 1 0 1 1 1 0 Cytochrome oxidase c subunit VIb Ras PF00071.17 EIE82204.1 - 3.4e-40 137.0 0.1 4.5e-40 136.7 0.1 1.1 1 0 0 1 1 1 1 Ras family Arf PF00025.16 EIE82204.1 - 4.3e-10 39.1 0.2 5.1e-10 38.8 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 EIE82204.1 - 5.8e-10 39.7 0.1 1.5e-09 38.3 0.0 1.7 2 1 0 2 2 2 1 Miro-like protein GTP_EFTU PF00009.22 EIE82204.1 - 8.8e-06 25.2 0.0 1.1e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EIE82204.1 - 0.023 13.8 0.0 0.03 13.4 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region FeoB_N PF02421.13 EIE82204.1 - 0.047 12.9 0.1 0.068 12.4 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B ATP_bind_1 PF03029.12 EIE82204.1 - 0.055 12.9 0.0 0.073 12.5 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Botulinum_HA-17 PF05588.6 EIE82205.1 - 0.014 15.3 0.0 0.014 15.2 0.0 1.0 1 0 0 1 1 1 0 Clostridium botulinum HA-17 protein DUF2024 PF09630.5 EIE82205.1 - 0.13 11.9 0.0 0.16 11.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2024) DUF866 PF05907.8 EIE82206.1 - 0.039 13.4 1.4 0.06 12.8 1.0 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) Sterol-sensing PF12349.3 EIE82207.1 - 1.5e-26 92.7 3.7 4.3e-26 91.2 2.6 1.8 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation WD40 PF00400.27 EIE82207.1 - 4.6e-16 57.9 10.8 3.6e-06 26.6 0.3 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat Patched PF02460.13 EIE82207.1 - 2.5e-12 45.5 3.6 7.4e-12 44.0 0.6 2.1 2 0 0 2 2 2 1 Patched family Nup160 PF11715.3 EIE82207.1 - 0.00025 19.3 0.5 0.85 7.6 0.0 3.9 1 1 1 4 4 4 2 Nucleoporin Nup120/160 Y_phosphatase PF00102.22 EIE82209.1 - 4e-05 23.0 0.0 4.9e-05 22.7 0.0 1.3 1 1 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 EIE82209.1 - 0.012 15.1 0.0 0.042 13.4 0.0 1.9 1 1 0 1 1 1 0 Dual specificity phosphatase, catalytic domain DUF1977 PF09320.6 EIE82210.1 - 1e-13 51.4 0.7 1e-13 51.4 0.5 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1977) DnaJ PF00226.26 EIE82210.1 - 6.4e-06 25.8 2.3 7.3e-06 25.6 0.3 2.1 2 0 0 2 2 2 1 DnaJ domain TPR_2 PF07719.12 EIE82210.1 - 0.095 12.6 3.4 0.1 12.5 0.0 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat Fibrillarin PF01269.12 EIE82211.1 - 1.6e-111 370.7 0.1 2.3e-111 370.2 0.0 1.1 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 EIE82211.1 - 3.5e-05 23.4 0.0 5.5e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.1 EIE82211.1 - 0.00037 20.1 0.0 0.00059 19.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EIE82211.1 - 0.02 14.3 0.0 0.03 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Trehalase PF01204.13 EIE82212.1 - 2.5e-123 412.4 15.4 4.6e-122 408.2 10.7 1.9 1 1 0 1 1 1 1 Trehalase Bul1_C PF04426.7 EIE82212.1 - 0.03 13.5 0.5 0.066 12.3 0.3 1.5 1 0 0 1 1 1 0 Bul1 C terminus Arrestin_N PF00339.24 EIE82215.1 - 2.4e-07 30.7 0.7 0.0041 16.9 0.0 3.9 3 1 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Methyltransf_3 PF01596.12 EIE82218.1 - 1.3e-43 148.4 0.0 2.1e-43 147.7 0.0 1.3 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 EIE82218.1 - 1.2e-09 38.9 0.0 1.6e-09 38.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIE82218.1 - 5.1e-08 33.4 0.0 6.7e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIE82218.1 - 2e-05 24.2 0.0 2.5e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EIE82218.1 - 3.4e-05 23.4 0.0 4.5e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 EIE82218.1 - 0.00017 21.5 0.0 0.00024 21.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CmcI PF04989.7 EIE82218.1 - 0.0015 17.9 0.0 0.0016 17.7 0.0 1.1 1 0 0 1 1 1 1 Cephalosporin hydroxylase Methyltransf_16 PF10294.4 EIE82218.1 - 0.016 14.6 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase PrmA PF06325.8 EIE82218.1 - 0.062 12.4 0.0 0.081 12.0 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF2716 PF10898.3 EIE82218.1 - 0.09 12.7 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2716) DUF3712 PF12505.3 EIE82219.1 - 6.2e-12 45.6 0.0 2.2e-11 43.8 0.0 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3712) LEA_2 PF03168.8 EIE82219.1 - 0.00045 20.5 1.8 0.0016 18.7 0.0 2.7 3 0 0 3 3 3 1 Late embryogenesis abundant protein WD40 PF00400.27 EIE82221.1 - 2.5e-19 68.3 13.6 0.00016 21.4 0.6 6.0 5 0 0 5 5 5 5 WD domain, G-beta repeat Ribosomal_S26e PF01283.14 EIE82222.1 - 1.2e-51 173.6 9.0 1.4e-51 173.5 6.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Fer4_10 PF13237.1 EIE82222.1 - 0.19 11.5 3.7 0.66 9.8 0.9 2.0 1 1 1 2 2 2 0 4Fe-4S dicluster domain Zn_ribbon_2 PF12674.2 EIE82222.1 - 0.24 11.7 2.2 1.2 9.4 0.1 2.1 1 1 1 2 2 2 0 Putative zinc ribbon domain Fer4_2 PF12797.2 EIE82222.1 - 0.37 10.8 3.3 0.72 9.8 0.6 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_7 PF12838.2 EIE82222.1 - 0.43 11.0 3.9 3.6 8.0 1.3 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_8 PF13183.1 EIE82222.1 - 0.63 10.1 3.7 1.8 8.6 2.5 1.8 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4 PF00037.22 EIE82222.1 - 1.1 8.9 4.7 0.76 9.4 0.7 2.1 2 0 0 2 2 2 0 4Fe-4S binding domain KAR9 PF08580.5 EIE82225.1 - 1.2e-05 23.8 18.9 1.2e-05 23.8 13.1 2.9 2 1 0 2 2 2 1 Yeast cortical protein KAR9 GAS2 PF02187.12 EIE82225.1 - 8.3e-05 22.2 0.2 0.00029 20.5 0.0 2.0 2 0 0 2 2 2 1 Growth-Arrest-Specific Protein 2 Domain DUF1664 PF07889.7 EIE82225.1 - 0.67 9.7 9.1 0.27 11.0 2.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) CPSase_L_D2 PF02786.12 EIE82226.1 - 1.2e-80 269.7 0.3 2.2e-80 268.9 0.2 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 EIE82226.1 - 1.3e-68 230.2 0.0 2.7e-68 229.2 0.0 1.5 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 EIE82226.1 - 3.5e-35 120.4 0.0 9.2e-35 119.0 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EIE82226.1 - 1.9e-31 108.1 0.0 5.6e-31 106.6 0.0 1.9 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 EIE82226.1 - 1.1e-29 103.7 0.3 2.8e-29 102.4 0.0 1.9 2 0 0 2 2 2 1 HMGL-like ATPgrasp_Ter PF15632.1 EIE82226.1 - 6.8e-19 67.7 0.4 3.6e-18 65.3 0.0 2.3 2 1 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl PF00364.17 EIE82226.1 - 1.2e-18 66.5 1.9 3.9e-18 64.8 1.3 2.0 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 EIE82226.1 - 1.2e-17 64.2 0.1 2.4e-17 63.2 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 EIE82226.1 - 5e-15 54.9 0.8 1.1e-07 31.4 0.0 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.8 EIE82226.1 - 3.5e-11 42.8 0.0 7e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus HlyD PF00529.15 EIE82226.1 - 3.7e-08 33.0 0.4 0.0004 19.7 0.0 2.3 1 1 1 2 2 2 2 HlyD family secretion protein HlyD_3 PF13437.1 EIE82226.1 - 4.7e-08 33.3 1.5 0.012 15.9 0.0 3.2 3 0 0 3 3 3 2 HlyD family secretion protein ATP-grasp PF02222.17 EIE82226.1 - 7.3e-08 31.9 0.0 1.5e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 EIE82226.1 - 2e-07 30.6 0.2 7.1e-07 28.8 0.1 1.9 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 EIE82226.1 - 0.00015 21.6 0.0 0.00038 20.3 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain HlyD_2 PF12700.2 EIE82226.1 - 0.00016 20.9 0.2 0.12 11.5 0.0 2.3 1 1 1 2 2 2 2 HlyD family secretion protein NQRA PF05896.6 EIE82226.1 - 0.0071 15.5 0.2 0.014 14.6 0.1 1.4 1 0 0 1 1 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) DUF2118 PF09891.4 EIE82226.1 - 0.016 14.8 0.2 0.045 13.4 0.1 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) GCV_H PF01597.14 EIE82226.1 - 0.067 12.8 0.2 0.19 11.3 0.2 1.8 1 0 0 1 1 1 0 Glycine cleavage H-protein UDPGT PF00201.13 EIE82227.1 - 5.4e-20 71.4 0.0 7.8e-20 70.8 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 EIE82227.1 - 5.3e-05 22.9 0.0 9.5e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 EIE82227.1 - 0.0006 19.1 0.0 0.015 14.4 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 1 tRNA_int_end_N2 PF12928.2 EIE82228.1 - 6.1e-08 32.0 0.0 1e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.9 EIE82228.1 - 1.8e-05 24.2 0.0 3.4e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain DUF294 PF03445.8 EIE82228.1 - 0.032 13.8 0.0 0.055 13.0 0.0 1.3 1 0 0 1 1 1 0 Putative nucleotidyltransferase DUF294 MatE PF01554.13 EIE82229.1 - 3.1e-59 199.2 23.8 2.4e-30 105.3 4.9 2.4 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 EIE82229.1 - 6.8e-07 29.1 30.2 9.9e-06 25.4 4.6 3.8 3 1 1 4 4 4 2 Polysaccharide biosynthesis C-terminal domain Methyltransf_31 PF13847.1 EIE82230.1 - 2e-14 53.4 0.0 3.9e-14 52.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIE82230.1 - 7e-14 52.0 0.0 1.5e-13 51.0 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIE82230.1 - 2.7e-11 44.0 0.0 1.1e-10 42.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIE82230.1 - 5.2e-11 42.5 0.0 9.7e-11 41.6 0.0 1.4 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIE82230.1 - 5.2e-10 38.8 0.0 9.8e-10 37.9 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EIE82230.1 - 5.2e-09 36.3 0.0 8.7e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EIE82230.1 - 6.9e-07 28.5 0.0 7.4e-06 25.1 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_12 PF08242.7 EIE82230.1 - 1.4e-05 25.4 0.0 2.4e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EIE82230.1 - 0.00038 20.1 0.0 0.00073 19.2 0.0 1.5 1 1 0 1 1 1 1 Hypothetical methyltransferase TehB PF03848.9 EIE82230.1 - 0.00058 19.0 0.0 0.0014 17.8 0.0 1.6 2 0 0 2 2 2 1 Tellurite resistance protein TehB Methyltransf_26 PF13659.1 EIE82230.1 - 0.0011 18.9 0.0 0.0024 17.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EIE82230.1 - 0.0022 17.3 0.0 0.0052 16.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain MetW PF07021.7 EIE82230.1 - 0.0023 17.3 0.0 0.0035 16.7 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PCMT PF01135.14 EIE82230.1 - 0.0031 17.0 0.0 0.0056 16.2 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_9 PF08003.6 EIE82230.1 - 0.0032 16.1 0.0 0.0056 15.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) FtsJ PF01728.14 EIE82230.1 - 0.01 15.8 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase CMAS PF02353.15 EIE82230.1 - 0.015 14.3 0.5 0.031 13.3 0.0 1.8 2 1 0 2 2 2 0 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.1 EIE82230.1 - 0.051 13.2 0.0 0.079 12.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.13 EIE82230.1 - 0.082 12.0 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase IF-2B PF01008.12 EIE82231.1 - 6.9e-58 195.8 0.0 8.2e-58 195.6 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Skp1_POZ PF03931.10 EIE82232.1 - 2.5e-13 49.9 0.0 5.1e-13 48.9 0.0 1.5 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain Pyrid_oxidase_2 PF13883.1 EIE82233.1 - 2e-15 56.9 0.0 2.4e-15 56.6 0.0 1.0 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase TPMT PF05724.6 EIE82233.1 - 0.092 12.1 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Laminin_II PF06009.7 EIE82234.1 - 0.028 14.1 0.2 0.033 13.9 0.1 1.1 1 0 0 1 1 1 0 Laminin Domain II Aha1_N PF09229.6 EIE82235.1 - 8.1e-36 122.8 1.8 1.4e-35 122.0 1.2 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 EIE82235.1 - 1e-17 64.3 1.5 2.4e-17 63.1 1.0 1.7 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.4 EIE82235.1 - 0.013 15.6 0.9 0.031 14.4 0.6 1.7 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport p450 PF00067.17 EIE82236.1 - 4e-81 272.8 0.0 4.9e-81 272.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PMBR PF09373.5 EIE82236.1 - 0.089 12.7 0.1 0.3 11.1 0.0 1.9 1 0 0 1 1 1 0 Pseudomurein-binding repeat E2_bind PF08825.5 EIE82236.1 - 0.17 11.6 1.0 2.6 7.8 0.1 2.4 2 0 0 2 2 2 0 E2 binding domain p450 PF00067.17 EIE82237.1 - 6.2e-66 222.8 0.1 2.4e-64 217.5 0.1 2.0 1 1 0 1 1 1 1 Cytochrome P450 UPF0052 PF01933.13 EIE82240.1 - 4.2e-51 174.0 0.0 5.3e-51 173.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 NMT1 PF09084.6 EIE82241.1 - 2.6e-71 239.6 0.0 3.2e-71 239.3 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like Phosphonate-bd PF12974.2 EIE82241.1 - 2.7e-05 23.6 0.0 4.6e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1_2 PF13379.1 EIE82241.1 - 0.0031 16.9 0.1 1.1 8.6 0.0 2.9 2 1 1 3 3 3 2 NMT1-like family PBP_like PF12727.2 EIE82241.1 - 0.012 14.5 0.0 1.2 8.0 0.0 2.2 2 0 0 2 2 2 0 PBP superfamily domain UPF0370 PF13980.1 EIE82242.1 - 0.1 12.4 0.0 0.26 11.1 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) Pkinase PF00069.20 EIE82243.1 - 1.8e-55 187.9 0.0 2.5e-55 187.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE82243.1 - 1.7e-40 138.7 0.0 4.2e-39 134.1 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE82243.1 - 0.0024 16.8 0.0 0.039 12.9 0.0 2.1 1 1 0 1 1 1 1 Kinase-like DUF2419 PF10343.4 EIE82244.1 - 2.6e-27 95.8 0.3 1.4e-26 93.3 0.2 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF2419) CBFD_NFYB_HMF PF00808.18 EIE82245.1 - 6.9e-20 70.8 0.7 1.2e-19 70.0 0.0 1.8 3 0 0 3 3 3 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EIE82245.1 - 1.7e-08 34.4 0.1 3.1e-08 33.6 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 DrrA_P4M PF14860.1 EIE82245.1 - 0.065 12.9 3.9 0.083 12.6 2.7 1.3 1 0 0 1 1 1 0 DrrA phosphatidylinositol 4-phosphate binding domain MiaE_2 PF13794.1 EIE82245.1 - 0.09 12.2 0.1 0.11 11.9 0.1 1.2 1 0 0 1 1 1 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like RNase_H2-Ydr279 PF09468.5 EIE82245.1 - 0.093 11.9 4.1 0.12 11.5 2.9 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) PHD PF00628.24 EIE82246.1 - 1.2e-08 34.5 11.9 1.2e-08 34.5 8.3 1.6 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.1 EIE82246.1 - 0.0014 17.8 6.2 0.0024 17.1 4.3 1.4 1 0 0 1 1 1 1 PHD-finger DTHCT PF08070.6 EIE82246.1 - 0.025 15.1 3.5 0.056 14.0 0.3 2.2 2 0 0 2 2 2 0 DTHCT (NUC029) region Sox_C_TAD PF12067.3 EIE82246.1 - 0.046 13.8 1.4 0.063 13.4 0.2 1.7 2 0 0 2 2 2 0 Sox C-terminal transactivation domain zf-CW PF07496.10 EIE82246.1 - 0.088 12.5 4.1 0.26 11.0 2.8 1.8 1 0 0 1 1 1 0 CW-type Zinc Finger FXR1P_C PF12235.3 EIE82246.1 - 0.097 12.7 7.4 3.1 7.8 2.0 2.2 2 0 0 2 2 2 0 Fragile X-related 1 protein C terminal BTD PF09270.5 EIE82248.1 - 1.2e-24 86.8 0.1 5e-24 84.8 0.1 2.1 2 0 0 2 2 2 1 Beta-trefoil DNA-binding domain LAG1-DNAbind PF09271.6 EIE82248.1 - 3.9e-21 75.9 7.7 4.8e-12 46.5 0.2 3.0 2 1 1 3 3 3 2 LAG1, DNA binding PrkA PF06798.7 EIE82248.1 - 0.057 12.7 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 PrkA serine protein kinase C-terminal domain dCMP_cyt_deam_1 PF00383.17 EIE82249.1 - 2.1e-25 88.3 0.6 2.5e-25 88.0 0.4 1.0 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.1 EIE82249.1 - 8.6e-05 22.2 0.2 0.00014 21.5 0.1 1.4 1 1 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.1 EIE82249.1 - 0.017 14.9 2.1 0.31 10.9 0.2 2.1 1 1 1 2 2 2 0 Bd3614-like deaminase PP2C PF00481.16 EIE82250.1 - 1.1e-80 270.7 0.0 1.3e-80 270.4 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EIE82250.1 - 7.2e-06 25.8 0.0 0.04 13.6 0.0 2.2 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 EIE82250.1 - 0.00047 19.6 0.0 0.00094 18.6 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C Cupin_8 PF13621.1 EIE82251.1 - 7.1e-11 42.0 2.6 2e-10 40.6 0.0 2.3 2 0 0 2 2 2 1 Cupin-like domain JmjC PF02373.17 EIE82251.1 - 2.1e-09 37.6 0.1 6.1e-08 32.8 0.1 2.8 1 1 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.24 EIE82251.1 - 2.1e-08 33.6 8.7 2.1e-08 33.6 6.0 1.9 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.1 EIE82251.1 - 0.059 12.6 6.6 0.032 13.5 2.8 1.9 2 0 0 2 2 2 0 PHD-finger Pox_Ag35 PF03286.9 EIE82251.1 - 0.072 12.6 14.9 0.13 11.8 10.3 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Acyl-CoA_dh_1 PF00441.19 EIE82252.1 - 5.2e-19 68.8 0.0 1e-18 67.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EIE82252.1 - 6.8e-09 35.1 0.3 1.1e-08 34.4 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EIE82252.1 - 1.7e-06 28.2 0.0 0.0002 21.5 0.0 2.3 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain DUF883 PF05957.8 EIE82254.1 - 0.00092 19.5 31.7 0.19 12.1 10.7 3.8 1 1 2 3 3 3 3 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.13 EIE82254.1 - 0.002 17.6 14.2 0.0038 16.7 4.7 2.1 1 1 0 2 2 2 2 Apolipoprotein A1/A4/E domain Ribosomal_L22 PF00237.14 EIE82254.1 - 0.062 13.2 10.8 0.66 9.9 0.5 3.0 2 1 0 2 2 2 0 Ribosomal protein L22p/L17e YtxH PF12732.2 EIE82254.1 - 1.7 9.0 34.4 3.5 8.0 4.5 4.1 1 1 1 2 2 2 0 YtxH-like protein XOO_2897-deam PF14440.1 EIE82254.1 - 1.8 8.3 5.8 0.17 11.5 0.4 2.0 2 1 0 2 2 2 0 Xanthomonas XOO_2897-like deaminase Spo7 PF03907.8 EIE82255.1 - 3.1e-20 72.6 7.9 2.2e-18 66.6 1.8 2.0 1 1 1 2 2 2 2 Spo7-like protein Tmemb_18A PF09771.4 EIE82255.1 - 7.5e-05 22.7 0.0 0.00011 22.2 0.0 1.2 1 0 0 1 1 1 1 Transmembrane protein 188 DUF3410 PF11890.3 EIE82255.1 - 0.042 13.5 0.1 0.066 12.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3410) DUF1674 PF07896.7 EIE82256.1 - 1.4e-15 57.2 0.8 1.8e-15 56.8 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1674) CutA1 PF03091.10 EIE82257.1 - 0.035 13.7 0.0 0.035 13.7 0.0 1.1 1 0 0 1 1 1 0 CutA1 divalent ion tolerance protein CD47 PF04549.9 EIE82259.1 - 0.01 15.8 5.1 0.015 15.3 3.5 1.3 1 1 0 1 1 1 0 CD47 transmembrane region DUF962 PF06127.6 EIE82260.1 - 7.2e-23 80.3 2.1 1e-22 79.8 1.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF962) Prenyltrans PF00432.16 EIE82261.1 - 1e-61 204.0 8.3 3.6e-17 61.6 0.0 5.8 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EIE82261.1 - 4.1e-55 185.0 0.1 1.8e-19 70.2 0.0 3.6 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 EIE82261.1 - 5.7e-16 58.4 0.1 3.9e-12 46.1 0.0 3.4 1 1 2 3 3 3 2 Prenyltransferase-like A2M_comp PF07678.9 EIE82261.1 - 0.0003 20.1 0.1 0.36 10.0 0.0 3.4 3 1 1 4 4 4 2 A-macroglobulin complement component BAG PF02179.11 EIE82261.1 - 0.018 15.1 0.0 1.4 9.1 0.0 2.4 1 1 1 2 2 2 0 BAG domain RRM_1 PF00076.17 EIE82262.1 - 3.8e-14 52.0 0.0 4.7e-10 38.9 0.0 3.2 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) La PF05383.12 EIE82262.1 - 8e-11 41.5 0.1 2.8e-10 39.8 0.0 2.0 2 0 0 2 2 2 1 La domain RRM_6 PF14259.1 EIE82262.1 - 6.7e-06 26.0 0.0 4.5e-05 23.3 0.0 2.4 2 1 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE82262.1 - 0.00011 21.9 0.0 0.00029 20.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NUFIP2 PF15293.1 EIE82262.1 - 0.0099 14.6 0.6 0.013 14.2 0.4 1.1 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 2 AIF_C PF14721.1 EIE82262.1 - 0.35 11.1 4.0 0.16 12.2 1.1 1.6 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term CBFD_NFYB_HMF PF00808.18 EIE82263.1 - 5.3e-15 55.2 0.8 8.7e-15 54.5 0.5 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EIE82263.1 - 4.3e-09 36.3 0.1 7.5e-09 35.5 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 APC_CDC26 PF10471.4 EIE82263.1 - 2.8 8.7 21.4 0.26 12.0 11.0 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 zf-H2C2_2 PF13465.1 EIE82264.1 - 5.9e-14 51.5 17.2 1.1e-07 31.7 3.2 3.2 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 EIE82264.1 - 3.7e-12 45.8 9.3 5.5e-06 26.4 1.6 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIE82264.1 - 4.7e-11 42.2 9.5 1.2e-05 25.2 0.9 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-BED PF02892.10 EIE82264.1 - 0.018 14.7 3.4 0.031 14.0 1.9 1.7 1 1 1 2 2 2 0 BED zinc finger zf-RING_3 PF14369.1 EIE82264.1 - 0.047 13.7 1.8 2 8.4 0.0 2.7 3 0 0 3 3 3 0 zinc-finger zf-C2H2_2 PF12756.2 EIE82264.1 - 0.053 13.6 0.4 1.2 9.3 0.1 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 EIE82264.1 - 0.069 13.3 0.2 0.79 9.9 0.0 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-CHCC PF10276.4 EIE82264.1 - 0.27 11.0 2.9 0.33 10.8 0.7 1.9 1 1 1 2 2 2 0 Zinc-finger domain zf-Di19 PF05605.7 EIE82264.1 - 1.1 9.3 4.3 2.4 8.3 3.0 1.6 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding TPK_B1_binding PF04265.9 EIE82265.1 - 1.4e-18 66.3 0.0 2.4e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain TPK_catalytic PF04263.11 EIE82265.1 - 2.7e-18 65.7 0.0 4.7e-18 64.9 0.0 1.4 1 1 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain SHIPPO-rpt PF07004.7 EIE82266.1 - 0.0033 18.2 0.0 0.011 16.6 0.0 1.9 1 0 0 1 1 1 1 Sperm-tail PG-rich repeat TPR_MLP1_2 PF07926.7 EIE82266.1 - 0.0061 16.3 18.5 0.0061 16.3 12.9 3.8 1 1 3 4 4 4 1 TPR/MLP1/MLP2-like protein His_binding PF02098.11 EIE82266.1 - 5.8 6.7 11.1 2.3 8.0 1.2 2.7 2 1 1 3 3 3 0 Tick histamine binding protein Rgp1 PF08737.5 EIE82267.1 - 9.7e-28 97.3 0.0 1.1e-27 97.1 0.0 1.0 1 0 0 1 1 1 1 Rgp1 Rgp1 PF08737.5 EIE82268.1 - 8.7e-13 48.1 3.1 1.2e-06 27.8 0.1 3.0 2 1 1 3 3 3 2 Rgp1 4HBT_3 PF13622.1 EIE82268.1 - 0.0059 16.3 1.7 0.0064 16.2 1.1 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF974 PF06159.8 EIE82268.1 - 0.026 13.9 0.1 0.033 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF974) Big_5 PF13205.1 EIE82268.1 - 1.5 9.5 10.5 17 6.0 7.3 2.1 1 1 0 1 1 1 0 Bacterial Ig-like domain Pro_isomerase PF00160.16 EIE82269.1 - 4.2e-41 140.7 0.0 6.8e-41 140.0 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 EIE82269.1 - 3.3e-17 61.8 0.0 5.8e-17 61.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE82269.1 - 8.7e-14 51.2 0.0 1.7e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE82269.1 - 2.5e-09 36.8 0.0 5.9e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) VRR_NUC PF08774.6 EIE82270.1 - 0.0073 16.3 0.0 0.019 14.9 0.0 1.8 1 1 0 1 1 1 1 VRR-NUC domain PIF1 PF05970.9 EIE82272.1 - 2.5e-59 201.0 0.0 2.9e-59 200.8 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase P22_CoatProtein PF11651.3 EIE82272.1 - 0.05 12.1 0.0 0.066 11.7 0.0 1.1 1 0 0 1 1 1 0 P22 coat protein - gene protein 5 Ribosomal_L29 PF00831.18 EIE82273.1 - 3e-14 52.4 2.0 3e-14 52.4 1.4 2.1 2 1 0 2 2 2 1 Ribosomal L29 protein Ribosomal_S9 PF00380.14 EIE82273.1 - 0.043 14.0 3.4 0.072 13.3 2.3 1.5 1 1 0 1 1 1 0 Ribosomal protein S9/S16 GD_AH_C PF04295.8 EIE82273.1 - 0.11 11.0 0.8 0.14 10.7 0.6 1.1 1 0 0 1 1 1 0 D-galactarate dehydratase / Altronate hydrolase, C terminus CENP-B_N PF04218.8 EIE82273.1 - 2.7 7.4 5.3 6.7 6.2 0.0 2.9 3 0 0 3 3 3 0 CENP-B N-terminal DNA-binding domain CHAD PF05235.9 EIE82275.1 - 0.019 14.5 0.8 0.028 13.9 0.5 1.3 1 0 0 1 1 1 0 CHAD domain ChpXY PF10216.4 EIE82275.1 - 0.11 11.3 0.4 0.22 10.3 0.2 1.5 1 0 0 1 1 1 0 CO2 hydration protein (ChpXY) Ribosomal_S7 PF00177.16 EIE82276.1 - 1.6e-39 134.8 0.4 1.9e-39 134.5 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e DAHP_synth_1 PF00793.15 EIE82277.1 - 1.5e-100 335.3 0.0 1.8e-100 335.1 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family DUF3018 PF11455.3 EIE82277.1 - 0.097 12.6 0.2 0.33 10.9 0.0 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3018) MMR_HSR1 PF01926.18 EIE82278.1 - 2e-20 72.8 0.6 7.2e-15 54.9 0.0 2.3 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 EIE82278.1 - 6.5e-10 38.5 0.4 3.6e-06 26.3 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B GTP_EFTU PF00009.22 EIE82278.1 - 2.6e-07 30.2 0.2 4.3e-05 23.0 0.0 2.9 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EIE82278.1 - 1e-05 25.4 2.6 0.021 14.6 0.4 3.3 2 1 1 3 3 3 2 Dynamin family Gtr1_RagA PF04670.7 EIE82278.1 - 0.0045 16.1 0.3 0.13 11.3 0.1 2.2 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region DUF258 PF03193.11 EIE82278.1 - 0.01 15.0 0.2 0.034 13.3 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AIG1 PF04548.11 EIE82278.1 - 0.02 13.9 0.5 0.12 11.4 0.1 2.1 2 0 0 2 2 2 0 AIG1 family cobW PF02492.14 EIE82278.1 - 0.033 13.6 0.5 0.28 10.6 0.0 2.7 1 1 3 4 4 4 0 CobW/HypB/UreG, nucleotide-binding domain Miro PF08477.8 EIE82278.1 - 0.033 14.6 0.6 2 8.8 0.0 2.7 3 0 0 3 3 3 0 Miro-like protein Arf PF00025.16 EIE82278.1 - 0.041 13.1 0.4 3.7 6.7 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family SOBP PF15279.1 EIE82280.1 - 5.9 7.1 7.6 8.8 6.6 5.2 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein PIN_2 PF10130.4 EIE82281.1 - 1.3 9.0 4.4 2 8.4 0.0 2.0 2 0 0 2 2 2 0 PIN domain EBV-NA3 PF05009.7 EIE82281.1 - 1.4 8.0 4.1 1.5 7.9 2.8 1.2 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) FYDLN_acid PF09538.5 EIE82281.1 - 2.7 8.6 10.9 3.5 8.2 7.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) DUF2457 PF10446.4 EIE82281.1 - 7.6 5.1 14.1 8.4 4.9 9.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Pox_I3 PF04661.7 EIE82281.1 - 8.8 5.0 7.0 11 4.7 4.8 1.1 1 0 0 1 1 1 0 Poxvirus I3 ssDNA-binding protein LRR_4 PF12799.2 EIE82282.1 - 2.2e-26 90.9 32.8 8.9e-08 31.5 0.5 5.5 3 2 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EIE82282.1 - 7.1e-14 51.3 27.0 1.2e-06 28.1 0.7 3.6 2 1 1 3 3 3 3 Leucine rich repeat LRR_9 PF14580.1 EIE82282.1 - 1.4e-13 50.8 10.0 6.5e-09 35.5 0.9 2.9 1 1 0 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.28 EIE82282.1 - 5.6e-11 40.8 21.3 0.9 9.8 0.0 8.4 8 0 0 8 8 8 5 Leucine Rich Repeat LRR_7 PF13504.1 EIE82282.1 - 3.6e-06 26.2 19.7 16 6.2 0.0 8.7 9 1 0 9 9 9 1 Leucine rich repeat ASFV_J13L PF05568.6 EIE82282.1 - 0.43 10.0 5.8 0.8 9.2 4.0 1.5 1 0 0 1 1 1 0 African swine fever virus J13L protein LRR_6 PF13516.1 EIE82282.1 - 1.3 9.3 33.7 14 6.1 0.5 8.0 4 2 3 7 7 7 0 Leucine Rich repeat RNA_pol_3_Rpc31 PF11705.3 EIE82283.1 - 1.4e-35 123.3 17.2 1.8e-35 122.9 11.9 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 BUD22 PF09073.5 EIE82283.1 - 0.0048 16.0 11.8 0.0053 15.8 8.2 1.1 1 0 0 1 1 1 1 BUD22 V-SNARE PF05008.10 EIE82283.1 - 0.02 15.0 1.8 0.042 14.0 1.3 1.4 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus DUF2670 PF10875.3 EIE82283.1 - 0.088 12.8 0.4 0.12 12.3 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2670) Pox_Ag35 PF03286.9 EIE82283.1 - 0.38 10.2 13.6 7.3 6.0 0.2 2.1 1 1 1 2 2 2 0 Pox virus Ag35 surface protein DUF4407 PF14362.1 EIE82283.1 - 1.6 7.6 7.3 2 7.3 5.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2457 PF10446.4 EIE82286.1 - 0.058 12.1 29.6 0.062 12.0 20.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Cwf_Cwc_15 PF04889.7 EIE82286.1 - 3.9 7.1 21.7 4.3 6.9 15.0 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TLP-20 PF06088.6 EIE82286.1 - 4 7.0 9.8 4.9 6.8 6.8 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) NOA36 PF06524.7 EIE82286.1 - 4.3 6.5 18.1 4.3 6.5 12.5 1.1 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.9 EIE82286.1 - 5.1 5.0 19.2 5 5.0 13.3 1.0 1 0 0 1 1 1 0 CDC45-like protein Mak16 PF04874.9 EIE82286.1 - 5.2 7.2 22.3 5.8 7.0 15.4 1.1 1 0 0 1 1 1 0 Mak16 protein C-terminal region S-antigen PF05756.6 EIE82286.1 - 5.3 7.1 11.8 6.1 6.8 8.2 1.3 1 0 0 1 1 1 0 S-antigen protein DUF1510 PF07423.6 EIE82286.1 - 6.8 5.9 13.9 6.7 6.0 9.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Paf1 PF03985.8 EIE82286.1 - 7.1 5.2 16.8 7.6 5.1 11.6 1.0 1 0 0 1 1 1 0 Paf1 BTV_NS2 PF04514.7 EIE82286.1 - 8.4 5.1 15.1 9.2 5.0 10.5 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 FYDLN_acid PF09538.5 EIE82286.1 - 8.6 6.9 23.5 9.1 6.9 16.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Nop14 PF04147.7 EIE82286.1 - 9.9 3.9 26.1 9.6 3.9 18.1 1.0 1 0 0 1 1 1 0 Nop14-like family SSrecog PF03531.9 EIE82287.1 - 6e-73 244.8 1.3 9.8e-73 244.1 0.4 1.7 2 0 0 2 2 2 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 EIE82287.1 - 4e-32 110.0 0.2 4.8e-30 103.3 0.0 2.6 2 0 0 2 2 2 2 Histone chaperone Rttp106-like PH PF00169.24 EIE82288.1 - 0.001 19.2 0.0 0.0025 17.9 0.0 1.7 1 0 0 1 1 1 1 PH domain RhoGEF PF00621.15 EIE82288.1 - 0.034 14.0 0.2 0.13 12.1 0.0 2.0 1 1 1 2 2 2 0 RhoGEF domain Gon7 PF08738.5 EIE82290.1 - 0.03 14.3 0.9 0.059 13.3 0.6 1.4 1 0 0 1 1 1 0 Gon7 family BTV_NS2 PF04514.7 EIE82290.1 - 2 7.2 5.2 3.3 6.5 3.6 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 WWE PF02825.15 EIE82291.1 - 0.11 11.8 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 WWE domain Zn_clus PF00172.13 EIE82292.1 - 0.00028 20.7 17.4 0.00042 20.1 12.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RTA1 PF04479.8 EIE82294.1 - 1.2e-25 90.3 12.1 1.3e-25 90.1 7.8 1.4 1 1 0 1 1 1 1 RTA1 like protein DUF1381 PF07129.6 EIE82294.1 - 0.11 11.8 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1381) Asp PF00026.18 EIE82295.1 - 3.1e-91 305.9 9.0 3.1e-91 305.9 6.2 1.5 2 0 0 2 2 2 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIE82295.1 - 3.3e-08 33.6 2.1 1.2e-06 28.5 0.6 3.2 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EIE82295.1 - 4.4e-05 23.9 1.0 0.091 13.2 0.1 2.9 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 EIE82295.1 - 0.00035 20.1 0.5 0.009 15.5 0.3 2.5 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal SR-25 PF10500.4 EIE82295.1 - 0.22 10.9 9.3 0.44 9.9 6.5 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF755 PF05501.6 EIE82295.1 - 0.25 11.4 6.9 0.51 10.4 4.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Asp PF00026.18 EIE82296.1 - 3.1e-91 305.9 9.0 3.1e-91 305.9 6.2 1.5 2 0 0 2 2 2 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIE82296.1 - 3.3e-08 33.6 2.1 1.2e-06 28.5 0.6 3.2 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EIE82296.1 - 4.4e-05 23.9 1.0 0.091 13.2 0.1 2.9 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 EIE82296.1 - 0.00035 20.1 0.5 0.009 15.5 0.3 2.5 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal SR-25 PF10500.4 EIE82296.1 - 0.22 10.9 9.3 0.44 9.9 6.5 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF755 PF05501.6 EIE82296.1 - 0.25 11.4 6.9 0.51 10.4 4.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Ribosomal_S24e PF01282.14 EIE82297.1 - 3.7e-36 122.7 0.4 5.6e-36 122.2 0.0 1.4 1 1 1 2 2 2 1 Ribosomal protein S24e Ribosomal_S2 PF00318.15 EIE82297.1 - 0.093 11.9 0.5 0.11 11.6 0.4 1.1 1 0 0 1 1 1 0 Ribosomal protein S2 Zip PF02535.17 EIE82298.1 - 3.5e-58 197.1 18.5 1e-55 188.9 12.8 2.2 1 1 0 1 1 1 1 ZIP Zinc transporter FtsX PF02687.16 EIE82298.1 - 0.013 15.2 0.5 0.013 15.2 0.4 3.0 2 1 1 3 3 3 0 FtsX-like permease family DUF1869 PF08956.5 EIE82299.1 - 0.22 11.1 1.0 0.37 10.4 0.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1869) Acetyltransf_7 PF13508.1 EIE82300.1 - 3.7e-11 43.0 0.0 1e-10 41.5 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EIE82300.1 - 1.8e-09 37.5 0.0 3.9e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EIE82300.1 - 4.9e-07 29.4 0.0 1.1e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 EIE82300.1 - 2.2e-05 24.3 0.0 4e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EIE82300.1 - 0.00035 20.6 0.0 0.00061 19.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EIE82300.1 - 0.021 14.9 0.0 0.027 14.6 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EIE82300.1 - 0.093 12.6 0.1 0.27 11.1 0.0 1.7 1 1 1 2 2 2 0 GCN5-related N-acetyl-transferase DZR PF12773.2 EIE82301.1 - 0.44 10.4 3.5 0.98 9.2 2.4 1.6 1 0 0 1 1 1 0 Double zinc ribbon LIM PF00412.17 EIE82302.1 - 0.02 14.9 0.1 0.041 13.9 0.1 1.6 1 0 0 1 1 1 0 LIM domain bZIP_1 PF00170.16 EIE82303.1 - 2.3e-06 27.4 13.6 4.8e-06 26.4 9.4 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EIE82303.1 - 4.1e-06 26.4 18.4 5.7e-06 26.0 11.1 2.1 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_Maf PF03131.12 EIE82303.1 - 0.0011 19.2 10.8 0.0017 18.6 7.5 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor PRP1_N PF06424.7 EIE82303.1 - 0.033 14.5 3.9 0.059 13.6 2.7 1.4 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal FTA2 PF13095.1 EIE82303.1 - 0.053 13.1 0.5 0.094 12.3 0.3 1.4 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 IncA PF04156.9 EIE82303.1 - 0.058 12.9 5.4 0.088 12.3 3.8 1.3 1 0 0 1 1 1 0 IncA protein HAUS6_N PF14661.1 EIE82303.1 - 0.077 12.3 6.5 0.11 11.8 4.5 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF972 PF06156.8 EIE82303.1 - 0.13 12.6 10.6 0.23 11.8 4.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF3186 PF11382.3 EIE82303.1 - 0.49 9.4 3.3 0.21 10.6 0.4 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3186) EMP24_GP25L PF01105.19 EIE82303.1 - 0.51 10.0 4.5 0.69 9.6 3.1 1.2 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF342 PF03961.8 EIE82303.1 - 0.57 8.5 5.2 0.69 8.2 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF4407 PF14362.1 EIE82303.1 - 0.84 8.5 3.9 1.1 8.1 2.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) OmpH PF03938.9 EIE82303.1 - 0.89 9.4 8.3 1.4 8.8 5.7 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) APG6 PF04111.7 EIE82303.1 - 0.94 8.4 9.0 1.2 8.1 6.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DivIC PF04977.10 EIE82303.1 - 0.96 8.9 10.1 5.4 6.5 7.0 2.1 1 1 0 1 1 1 0 Septum formation initiator GBP_C PF02841.9 EIE82303.1 - 1.3 8.1 11.7 1.7 7.7 8.1 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Proteasome PF00227.21 EIE82304.1 - 3e-45 153.8 0.2 1.9e-42 144.7 0.1 2.1 1 1 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EIE82304.1 - 1.6e-11 43.3 0.0 2.7e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF1669 PF07894.7 EIE82304.1 - 0.026 13.7 0.1 0.038 13.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1669) DnaJ PF00226.26 EIE82305.1 - 1.4e-08 34.3 0.1 2.3e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 EIE82305.1 - 0.0057 16.4 0.0 0.0059 16.3 0.0 1.2 1 0 0 1 1 1 1 Pam16 DUF3967 PF13152.1 EIE82305.1 - 0.045 13.4 0.3 0.49 10.0 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3967) Peptidase_M24 PF00557.19 EIE82306.1 - 2.6e-28 99.0 0.4 3.3e-28 98.6 0.3 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Myb_DNA-bind_6 PF13921.1 EIE82307.1 - 0.015 15.3 0.2 0.049 13.7 0.1 2.0 1 0 0 1 1 1 0 Myb-like DNA-binding domain BAF1_ABF1 PF04684.8 EIE82307.1 - 0.03 13.1 7.4 0.039 12.7 5.1 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF4551 PF15087.1 EIE82307.1 - 0.1 10.9 14.4 0.13 10.6 10.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF3276 PF11680.3 EIE82307.1 - 0.29 10.9 10.7 0.45 10.3 1.4 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3276) Lin-8 PF03353.10 EIE82307.1 - 0.51 9.5 17.2 0.77 8.9 11.9 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist CDK2AP PF09806.4 EIE82307.1 - 0.63 10.2 14.4 0.13 12.4 7.6 1.5 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein DUF3371 PF11851.3 EIE82307.1 - 0.71 10.5 16.5 0.036 14.7 7.2 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF3371) PHD_3 PF13922.1 EIE82307.1 - 4.1 7.7 10.2 12 6.2 7.1 1.8 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx HMG_box PF00505.14 EIE82308.1 - 2.4e-15 56.5 2.2 2.4e-15 56.5 1.5 2.4 3 0 0 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EIE82308.1 - 1.5e-10 41.2 3.1 1.5e-10 41.2 2.2 2.9 2 1 1 3 3 3 1 HMG-box domain DUF1919 PF08942.5 EIE82308.1 - 0.029 13.7 0.2 0.029 13.7 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1919) Vma12 PF11712.3 EIE82308.1 - 3.4 7.3 11.1 15 5.2 7.7 2.2 1 1 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase FCH PF00611.18 EIE82309.1 - 6.3e-10 39.1 1.3 4.6e-09 36.3 0.0 2.7 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain YebO PF13974.1 EIE82309.1 - 0.037 13.7 1.6 0.12 12.1 1.1 1.8 1 0 0 1 1 1 0 YebO-like protein FliJ PF02050.11 EIE82309.1 - 0.047 13.7 2.2 0.14 12.1 1.5 1.7 1 0 0 1 1 1 0 Flagellar FliJ protein MCC-bdg_PDZ PF10506.4 EIE82309.1 - 0.094 12.5 0.2 0.27 11.0 0.2 1.8 1 0 0 1 1 1 0 PDZ domain of MCC-2 bdg protein for Usher syndrome HLH PF00010.21 EIE82310.1 - 3.3e-13 49.0 2.9 7.5e-13 47.9 2.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Vma12 PF11712.3 EIE82310.1 - 0.0074 15.9 0.5 0.0074 15.9 0.3 1.9 2 1 0 2 2 2 1 Endoplasmic reticulum-based factor for assembly of V-ATPase Pyrophosphatase PF00719.14 EIE82310.1 - 0.033 13.6 1.5 0.049 13.0 0.1 1.9 2 1 0 2 2 2 0 Inorganic pyrophosphatase Tropomyosin_1 PF12718.2 EIE82310.1 - 0.41 10.4 8.5 6.3 6.6 6.0 2.0 1 1 0 1 1 1 0 Tropomyosin like SLX9 PF15341.1 EIE82310.1 - 0.48 10.8 4.5 0.71 10.3 3.1 1.3 1 1 0 1 1 1 0 Ribosome biogenesis protein SLX9 DUF2654 PF10849.3 EIE82310.1 - 1.3 8.8 8.3 2.2 8.0 1.7 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2654) DUF4200 PF13863.1 EIE82310.1 - 1.4 8.9 13.4 3.6 7.5 2.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Myc-LZ PF02344.10 EIE82310.1 - 3.5 7.3 8.9 2.6 7.7 0.6 2.9 3 0 0 3 3 3 0 Myc leucine zipper domain zf-C2H2 PF00096.21 EIE82311.1 - 3.7e-11 42.6 9.1 6.3e-06 26.2 0.7 3.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIE82311.1 - 5.5e-10 38.8 7.9 3.8e-05 23.7 0.7 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EIE82311.1 - 8.8e-07 28.9 22.6 9.8e-07 28.7 1.7 3.8 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EIE82311.1 - 0.012 15.7 3.2 1.5 9.0 0.2 3.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EIE82311.1 - 0.12 12.3 3.1 0.73 9.8 0.6 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-TRAF PF02176.13 EIE82311.1 - 0.43 10.9 5.2 0.39 11.1 0.2 2.4 1 1 1 2 2 2 0 TRAF-type zinc finger zf-met PF12874.2 EIE82311.1 - 0.51 10.6 6.8 2.2 8.5 0.5 3.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type DUF4393 PF14337.1 EIE82314.1 - 0.012 15.0 0.1 0.035 13.5 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4393) Dopey_N PF04118.9 EIE82315.1 - 6.4e-36 123.6 0.0 1.2e-35 122.7 0.0 1.5 1 0 0 1 1 1 1 Dopey, N-terminal NOB1_Zn_bind PF08772.6 EIE82315.1 - 1.7e-29 101.4 3.6 4.3e-29 100.1 2.5 1.7 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like DZR PF12773.2 EIE82315.1 - 0.007 16.1 0.9 0.016 15.0 0.6 1.5 1 0 0 1 1 1 1 Double zinc ribbon PIN PF01850.16 EIE82315.1 - 0.028 14.7 0.0 0.076 13.3 0.0 1.8 1 0 0 1 1 1 0 PIN domain Rpr2 PF04032.11 EIE82315.1 - 0.042 13.7 1.6 0.08 12.8 0.3 2.1 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain AF1Q PF15017.1 EIE82315.1 - 0.067 13.1 14.2 0.41 10.5 9.9 2.3 1 1 0 1 1 1 0 Drug resistance and apoptosis regulator zf-ribbon_3 PF13248.1 EIE82315.1 - 0.074 12.2 2.5 0.19 10.9 1.7 1.7 1 0 0 1 1 1 0 zinc-ribbon domain DUF1936 PF09151.5 EIE82315.1 - 0.11 11.9 0.1 0.28 10.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1936) LysM PF01476.15 EIE82316.1 - 5.1e-10 39.0 0.1 1.1e-09 38.0 0.1 1.6 1 0 0 1 1 1 1 LysM domain DDE_3 PF13358.1 EIE82318.1 - 1.1e-17 64.1 0.0 2.9e-17 62.7 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE82318.1 - 2e-08 34.1 0.5 7.1e-08 32.3 0.4 2.0 2 1 0 2 2 2 1 Transposase DDE_3 PF13358.1 EIE82319.1 - 3.8e-16 59.1 0.0 8.9e-16 57.9 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE82319.1 - 1.6e-08 34.5 2.3 3.6e-08 33.3 0.2 2.5 2 1 1 3 3 3 1 Transposase HTH_23 PF13384.1 EIE82319.1 - 0.00033 20.2 0.0 0.00078 19.0 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_7 PF02796.10 EIE82319.1 - 0.02 14.7 0.0 0.051 13.4 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase NUDIX_4 PF14815.1 EIE82319.1 - 0.029 13.8 0.3 0.06 12.7 0.2 1.5 1 0 0 1 1 1 0 NUDIX domain Imm35 PF15581.1 EIE82319.1 - 0.11 12.4 0.0 0.38 10.7 0.0 1.9 1 0 0 1 1 1 0 Immunity protein 35 rve PF00665.21 EIE82323.1 - 3.5e-20 72.2 0.0 1.5e-19 70.3 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 EIE82323.1 - 1.3e-10 41.0 0.3 4.1e-10 39.3 0.2 1.9 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE82323.1 - 4.3e-07 29.5 2.4 9.9e-07 28.3 1.6 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.1 EIE82323.1 - 9.1e-07 29.3 0.2 7.4e-06 26.3 0.1 2.3 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.15 EIE82323.1 - 1.4e-05 24.9 0.0 3.8e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EIE82323.1 - 2.3e-05 24.1 0.0 5.2e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Tudor-knot PF11717.3 EIE82323.1 - 0.0063 16.1 0.9 0.021 14.5 0.6 1.9 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Asp_protease PF09668.5 EIE82323.1 - 0.042 13.4 0.0 0.13 11.8 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease DDE_3 PF13358.1 EIE82324.1 - 3.1e-13 49.6 0.2 4.1e-13 49.3 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE82324.1 - 0.029 14.4 0.0 0.042 13.9 0.0 1.3 1 0 0 1 1 1 0 Integrase core domain DUF1033 PF06279.6 EIE82324.1 - 0.049 13.4 0.8 0.077 12.8 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1033) Myb_DNA-bind_5 PF13873.1 EIE82324.1 - 0.13 12.1 0.5 11 6.0 0.2 2.5 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain HTH_Tnp_Tc3_2 PF01498.13 EIE82325.1 - 2e-10 40.6 1.1 3.7e-10 39.7 0.8 1.5 1 0 0 1 1 1 1 Transposase DUF2828 PF11443.3 EIE82325.1 - 0.02 13.0 0.3 0.02 13.1 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) HTH_Tnp_4 PF13613.1 EIE82325.1 - 0.023 14.2 0.0 0.052 13.0 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease DDE_3 PF13358.1 EIE82326.1 - 3.1e-21 75.6 0.1 5.4e-21 74.8 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE82326.1 - 5.6e-16 58.3 0.5 3.5e-15 55.8 0.2 2.4 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 EIE82326.1 - 2.8e-08 33.8 0.2 9e-08 32.2 0.2 1.8 2 0 0 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.1 EIE82326.1 - 0.00014 21.3 0.1 0.001 18.6 0.0 2.5 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.1 EIE82326.1 - 0.0012 18.7 0.0 0.0074 16.2 0.0 2.5 3 0 0 3 3 3 1 Helix-turn-helix domain rve PF00665.21 EIE82326.1 - 0.0034 17.4 0.0 0.015 15.3 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain ATC_hydrolase PF14196.1 EIE82326.1 - 0.0045 17.4 0.0 6.1 7.2 0.0 2.6 3 0 0 3 3 3 2 L-2-amino-thiazoline-4-carboxylic acid hydrolase HTH_40 PF14493.1 EIE82326.1 - 0.02 15.0 0.1 1.1 9.4 0.0 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_7 PF02796.10 EIE82326.1 - 0.023 14.5 0.1 0.081 12.8 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase Ku_PK_bind PF08785.6 EIE82326.1 - 0.051 13.4 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 Ku C terminal domain like HTH_17 PF12728.2 EIE82326.1 - 0.098 12.9 0.2 2.4 8.4 0.0 3.0 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_IclR PF09339.5 EIE82326.1 - 0.11 12.0 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.13 EIE82327.1 - 2.9e-07 30.4 0.8 8.1e-07 29.0 0.1 1.9 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 EIE82327.1 - 0.0093 16.0 0.1 0.02 15.0 0.0 1.6 2 0 0 2 2 2 1 Winged helix-turn helix rve PF00665.21 EIE82330.1 - 1e-17 64.3 0.0 3.7e-17 62.5 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 EIE82330.1 - 3.9e-14 52.5 0.9 1e-13 51.1 0.6 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE82330.1 - 2.2e-06 27.2 1.1 5.6e-06 25.9 0.7 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.1 EIE82330.1 - 4.8e-05 23.7 0.1 0.00046 20.6 0.0 2.4 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.15 EIE82330.1 - 0.00055 19.8 0.1 0.0021 17.9 0.0 2.1 1 0 0 1 1 1 1 Retroviral aspartyl protease Tudor-knot PF11717.3 EIE82330.1 - 0.02 14.6 0.7 0.054 13.2 0.5 1.8 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain YcgR_2 PF12945.2 EIE82330.1 - 0.02 14.7 0.0 0.42 10.5 0.0 2.6 2 0 0 2 2 2 0 Flagellar protein YcgR gag-asp_proteas PF13975.1 EIE82330.1 - 0.071 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.12 EIE82331.1 - 1.7e-05 24.8 2.3 0.00019 21.4 0.0 3.0 3 0 0 3 3 3 1 Retrotransposon gag protein Peptidase_M3_N PF08439.5 EIE82331.1 - 0.012 15.6 1.9 0.037 14.0 0.2 2.5 2 0 0 2 2 2 0 Oligopeptidase F DUF3479 PF11965.3 EIE82331.1 - 0.046 13.5 0.1 0.093 12.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3479) HTH_Tnp_Tc3_2 PF01498.13 EIE82332.1 - 4.8e-07 29.7 0.7 8.8e-07 28.9 0.1 1.7 2 0 0 2 2 2 1 Transposase HTH_Tnp_Tc3_2 PF01498.13 EIE82333.1 - 2e-10 40.5 1.1 3.8e-10 39.6 0.8 1.5 1 0 0 1 1 1 1 Transposase DUF2828 PF11443.3 EIE82333.1 - 0.021 13.0 0.3 0.021 13.0 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) HTH_Tnp_4 PF13613.1 EIE82333.1 - 0.024 14.1 0.0 0.053 13.0 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE82335.1 - 2e-10 40.5 1.1 3.8e-10 39.6 0.8 1.5 1 0 0 1 1 1 1 Transposase DUF2828 PF11443.3 EIE82335.1 - 0.021 13.0 0.3 0.021 13.0 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) HTH_Tnp_4 PF13613.1 EIE82335.1 - 0.024 14.1 0.0 0.053 13.0 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE82336.1 - 3.1e-07 30.3 1.9 5.2e-07 29.6 1.1 1.7 1 1 0 1 1 1 1 Transposase DDE_3 PF13358.1 EIE82336.1 - 0.0043 16.8 0.0 0.0092 15.7 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1049 PF06305.6 EIE82340.1 - 0.075 12.5 0.0 0.21 11.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) COG7 PF10191.4 EIE82341.1 - 0.019 12.8 0.1 0.022 12.6 0.1 1.1 1 0 0 1 1 1 0 Golgi complex component 7 (COG7) adh_short_C2 PF13561.1 EIE82342.1 - 1.9e-26 93.2 0.0 2.3e-26 93.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EIE82342.1 - 3.1e-18 66.2 0.1 4.5e-18 65.7 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIE82342.1 - 7.6e-07 28.9 0.0 1e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Sterol_MT_C PF08498.5 EIE82342.1 - 0.025 14.5 0.1 0.051 13.5 0.1 1.5 1 0 0 1 1 1 0 Sterol methyltransferase C-terminal COPI_assoc PF08507.5 EIE82343.1 - 0.012 15.3 0.5 0.13 11.9 0.7 1.9 1 1 1 2 2 2 0 COPI associated protein DUF3953 PF13129.1 EIE82343.1 - 0.33 10.6 2.8 0.68 9.6 1.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3953) Fasciclin PF02469.17 EIE82345.1 - 7.6e-20 71.2 15.3 9.6e-15 54.7 1.4 3.2 2 1 0 2 2 2 2 Fasciclin domain DUF4449 PF14613.1 EIE82346.1 - 2.3e-09 37.3 1.6 2.3e-09 37.3 1.1 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF4449) DnaG_DnaB_bind PF08278.6 EIE82346.1 - 0.05 13.8 0.6 0.05 13.8 0.4 3.9 3 1 1 4 4 4 0 DNA primase DnaG DnaB-binding Ribosomal_L4 PF00573.17 EIE82347.1 - 1.5e-44 151.7 1.2 1.5e-44 151.7 0.9 1.7 2 0 0 2 2 2 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 EIE82347.1 - 3.7e-29 100.4 4.1 3.7e-29 100.4 2.8 2.4 2 1 1 3 3 3 1 60S ribosomal protein L4 C-terminal domain Thymidylate_kin PF02223.12 EIE82348.1 - 1.5e-07 30.9 0.0 1.7e-07 30.7 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase MobB PF03205.9 EIE82348.1 - 0.001 18.7 0.0 0.0012 18.5 0.0 1.0 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 EIE82348.1 - 0.0011 19.1 0.0 0.0011 19.1 0.0 1.0 1 0 0 1 1 1 1 AAA domain ArgK PF03308.11 EIE82348.1 - 0.0019 17.0 0.0 0.002 16.9 0.0 1.0 1 0 0 1 1 1 1 ArgK protein PPK2 PF03976.9 EIE82348.1 - 0.0057 15.9 0.0 0.006 15.8 0.0 1.0 1 0 0 1 1 1 1 Polyphosphate kinase 2 (PPK2) APS_kinase PF01583.15 EIE82348.1 - 0.0089 15.6 0.0 0.01 15.5 0.0 1.0 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_14 PF13173.1 EIE82348.1 - 0.016 15.1 0.0 0.016 15.0 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EIE82348.1 - 0.021 15.1 0.0 0.021 15.1 0.0 1.0 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.5 EIE82348.1 - 0.041 13.0 0.0 0.046 12.9 0.0 1.0 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_35 PF14516.1 EIE82348.1 - 0.047 12.3 0.0 0.047 12.3 0.0 1.0 1 0 0 1 1 1 0 AAA-like domain AAA_28 PF13521.1 EIE82348.1 - 0.058 13.3 0.0 0.063 13.2 0.0 1.0 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EIE82348.1 - 0.072 12.8 0.0 0.078 12.6 0.0 1.0 1 0 0 1 1 1 0 NTPase DLIC PF05783.6 EIE82349.1 - 3.3e-70 237.0 4.7 1.4e-62 211.9 3.2 4.3 2 1 0 2 2 2 2 Dynein light intermediate chain (DLIC) ABC_tran PF00005.22 EIE82349.1 - 0.00016 22.0 0.0 0.00084 19.6 0.0 2.2 2 1 0 2 2 2 1 ABC transporter Miro PF08477.8 EIE82349.1 - 0.00044 20.7 0.1 0.011 16.2 0.0 2.8 2 1 1 3 3 3 1 Miro-like protein GTP_EFTU PF00009.22 EIE82349.1 - 0.0014 18.1 0.0 0.55 9.6 0.0 2.5 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 EIE82349.1 - 0.0028 17.1 0.1 0.0078 15.7 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain Sigma54_activ_2 PF14532.1 EIE82349.1 - 0.0065 16.5 0.0 0.026 14.5 0.0 2.0 2 0 0 2 2 1 1 Sigma-54 interaction domain AAA_18 PF13238.1 EIE82349.1 - 0.0082 16.4 0.0 0.051 13.8 0.0 2.5 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.1 EIE82349.1 - 0.0099 15.8 0.0 0.069 13.1 0.0 2.3 3 0 0 3 3 3 1 AAA ATPase domain DUF815 PF05673.8 EIE82349.1 - 0.023 13.6 0.0 0.044 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Septin PF00735.13 EIE82349.1 - 0.039 12.9 0.0 0.15 11.0 0.0 1.9 2 0 0 2 2 2 0 Septin AAA_22 PF13401.1 EIE82349.1 - 0.043 13.9 0.0 0.13 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 EIE82349.1 - 0.05 13.5 0.0 0.2 11.6 0.0 2.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF258 PF03193.11 EIE82349.1 - 0.06 12.5 0.0 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ATP_bind_1 PF03029.12 EIE82349.1 - 0.084 12.4 0.0 9.6 5.6 0.0 2.6 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_10 PF12846.2 EIE82349.1 - 0.1 12.0 0.1 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain FtsK_SpoIIIE PF01580.13 EIE82349.1 - 0.1 12.0 0.2 0.21 11.0 0.1 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family KilA-N PF04383.8 EIE82350.1 - 0.0014 18.2 0.0 0.026 14.1 0.0 2.1 1 1 0 1 1 1 1 KilA-N domain E1-E2_ATPase PF00122.15 EIE82351.1 - 3.2e-64 216.0 6.6 6.4e-64 215.1 1.8 2.5 1 1 1 2 2 2 2 E1-E2 ATPase Cation_ATPase_C PF00689.16 EIE82351.1 - 3.2e-47 160.3 10.7 4.9e-47 159.7 6.3 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EIE82351.1 - 1.4e-34 120.3 0.0 1.3e-33 117.2 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EIE82351.1 - 2.6e-20 71.6 0.0 7.2e-20 70.2 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 EIE82351.1 - 1.4e-19 69.8 0.1 3.1e-19 68.7 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EIE82351.1 - 4e-18 66.2 0.0 9.9e-18 64.9 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EIE82351.1 - 1.1e-08 35.0 2.1 1.1e-06 28.4 1.1 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EIE82351.1 - 0.0044 17.2 0.1 0.012 15.8 0.0 1.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase PADR1 PF08063.7 EIE82351.1 - 0.11 11.9 0.0 0.24 10.8 0.0 1.5 1 0 0 1 1 1 0 PADR1 (NUC008) domain HEAT_EZ PF13513.1 EIE82352.1 - 5e-24 84.1 0.1 5.7e-08 33.0 0.0 7.0 7 1 1 8 8 8 4 HEAT-like repeat HEAT PF02985.17 EIE82352.1 - 1.2e-15 56.0 0.2 0.007 16.3 0.0 7.0 6 0 0 6 6 6 3 HEAT repeat HEAT_2 PF13646.1 EIE82352.1 - 2.1e-13 50.3 0.0 1.8e-05 24.9 0.0 4.4 3 2 1 4 4 4 3 HEAT repeats Vac14_Fab1_bd PF12755.2 EIE82352.1 - 1.3e-06 28.7 0.1 2 8.8 0.0 5.2 5 1 0 6 6 6 2 Vacuolar 14 Fab1-binding region Arm PF00514.18 EIE82352.1 - 3.3e-06 26.7 2.3 0.77 9.6 0.0 5.6 5 1 0 5 5 5 2 Armadillo/beta-catenin-like repeat Cnd1 PF12717.2 EIE82352.1 - 0.00033 20.5 0.8 0.16 11.7 0.0 3.6 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.15 EIE82352.1 - 0.02 13.2 0.1 18 3.5 0.0 3.6 3 2 0 3 3 3 0 Adaptin N terminal region HEAT_PBS PF03130.11 EIE82352.1 - 0.027 14.9 0.4 2.8 8.6 0.0 4.5 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat XPC-binding PF09280.6 EIE82352.1 - 0.068 12.6 0.0 96 2.5 0.0 4.2 3 0 0 3 3 3 0 XPC-binding domain MMS19_C PF12460.3 EIE82352.1 - 0.16 10.6 6.6 4.6 5.8 0.1 4.3 5 0 0 5 5 5 0 RNAPII transcription regulator C-terminal HTH_29 PF13551.1 EIE82353.1 - 0.0033 17.5 0.0 0.0038 17.3 0.0 1.1 1 0 0 1 1 1 1 Winged helix-turn helix HTH_30 PF13556.1 EIE82353.1 - 0.052 13.1 0.0 0.081 12.5 0.0 1.4 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain Ribosomal_L15e PF00827.12 EIE82356.1 - 7.4e-90 299.6 12.3 8.5e-90 299.4 8.5 1.0 1 0 0 1 1 1 1 Ribosomal L15 ECH PF00378.15 EIE82357.1 - 1.5e-19 70.1 0.0 1.9e-19 69.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Orthopox_A43R PF06517.6 EIE82358.1 - 0.053 13.0 0.4 0.058 12.9 0.3 1.1 1 0 0 1 1 1 0 Orthopoxvirus A43R protein DUF2435 PF10363.4 EIE82358.1 - 0.11 12.4 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2435) CFEM PF05730.6 EIE82358.1 - 0.19 11.5 4.1 0.39 10.5 2.6 1.8 1 1 1 2 2 2 0 CFEM domain ASFV_J13L PF05568.6 EIE82359.1 - 0.0072 15.8 0.1 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 African swine fever virus J13L protein COG2 PF06148.6 EIE82359.1 - 0.19 11.5 10.2 0.026 14.3 3.1 2.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 HisKA_2 PF07568.7 EIE82359.1 - 0.23 11.3 3.1 0.47 10.3 0.2 2.9 3 1 0 3 3 3 0 Histidine kinase GAS PF13851.1 EIE82359.1 - 0.26 10.4 26.7 0.35 10.0 13.2 3.0 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Ribosomal_L16 PF00252.13 EIE82360.1 - 1.6e-19 69.9 0.2 1.9e-19 69.7 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e RTBV_P46 PF06216.6 EIE82360.1 - 0.071 11.9 0.0 0.081 11.7 0.0 1.1 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein DUF759 PF05537.6 EIE82363.1 - 0.0099 14.6 0.8 0.016 13.9 0.5 1.3 1 0 0 1 1 1 1 Borrelia burgdorferi protein of unknown function (DUF759) Phage_int_SAM_3 PF14659.1 EIE82363.1 - 1.3 9.3 5.2 6.3 7.1 0.0 3.4 3 0 0 3 3 3 0 Phage integrase, N-terminal SAM-like domain DEAD PF00270.24 EIE82365.1 - 0.00026 20.5 0.0 0.00034 20.1 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EIE82365.1 - 0.0072 16.1 0.0 0.0091 15.8 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C2H2_4 PF13894.1 EIE82366.1 - 0.022 15.0 4.4 0.045 14.0 3.0 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-UBP PF02148.14 EIE82366.1 - 0.025 14.6 0.6 0.029 14.4 0.4 1.3 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein zf-BED PF02892.10 EIE82366.1 - 0.038 13.7 0.2 0.058 13.1 0.2 1.3 1 0 0 1 1 1 0 BED zinc finger zf-met PF12874.2 EIE82366.1 - 0.54 10.5 6.2 3.5 7.9 4.3 2.1 1 1 0 1 1 1 0 Zinc-finger of C2H2 type SprA-related PF12118.3 EIE82367.1 - 0.18 11.1 36.0 0.24 10.7 24.9 1.1 1 0 0 1 1 1 0 SprA-related family Raftlin PF15250.1 EIE82367.1 - 0.68 8.3 19.3 0.87 8.0 13.4 1.2 1 0 0 1 1 1 0 Raftlin GAGA_bind PF06217.7 EIE82367.1 - 0.75 9.7 21.9 0.92 9.4 15.2 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family DUF4045 PF13254.1 EIE82367.1 - 2.2 7.4 26.0 2.7 7.1 18.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF262 PF03235.9 EIE82367.1 - 2.5 7.9 16.6 3.5 7.5 11.5 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF262 SID-1_RNA_chan PF13965.1 EIE82367.1 - 5.9 4.9 13.7 7.9 4.5 9.5 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Rgp1 PF08737.5 EIE82367.1 - 6.3 5.7 20.8 7.7 5.4 14.5 1.2 1 0 0 1 1 1 0 Rgp1 DUF2201_N PF13203.1 EIE82367.1 - 9.5 5.2 18.1 12 4.9 12.5 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain PLRV_ORF5 PF01690.12 EIE82367.1 - 9.6 5.2 27.5 12 4.9 19.1 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein bZIP_1 PF00170.16 EIE82368.1 - 1.3e-11 44.3 4.0 2.3e-11 43.5 2.8 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EIE82368.1 - 6.6e-11 41.8 4.8 1.2e-10 41.0 3.3 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EIE82368.1 - 0.002 18.3 5.5 0.0038 17.4 3.8 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor Aldedh PF00171.17 EIE82369.1 - 1.1e-116 389.8 0.2 1.7e-116 389.2 0.1 1.2 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Peptidase_C97 PF05903.9 EIE82371.1 - 1.3e-10 41.2 0.1 3.2e-10 39.9 0.1 1.7 2 0 0 2 2 2 1 PPPDE putative peptidase domain Thioredoxin PF00085.15 EIE82371.1 - 2.5e-06 27.1 0.0 3.6e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Fungal_trans PF04082.13 EIE82372.1 - 9.6e-10 37.7 1.6 1.2e-09 37.4 0.0 2.0 2 1 0 2 2 2 1 Fungal specific transcription factor domain 2-oxoacid_dh PF00198.18 EIE82374.1 - 9.2e-87 290.1 0.1 1.3e-86 289.6 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EIE82374.1 - 2.9e-18 65.2 0.7 6.8e-18 64.0 0.5 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 EIE82374.1 - 0.0016 18.0 0.3 0.23 11.1 0.0 2.7 2 0 0 2 2 2 2 Biotin-lipoyl like YtkA PF13115.1 EIE82374.1 - 0.21 11.9 3.4 0.29 11.4 0.1 2.5 2 0 0 2 2 2 0 YtkA-like DUF2611 PF11022.3 EIE82375.1 - 3.6e-24 84.6 0.1 3.9e-24 84.5 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2611) DPBB_1 PF03330.13 EIE82376.1 - 7.1e-12 45.1 0.4 1.3e-11 44.3 0.3 1.5 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EIE82376.1 - 1.1e-06 28.3 0.4 1.4e-06 28.0 0.2 1.2 1 0 0 1 1 1 1 Barwin family Motile_Sperm PF00635.21 EIE82377.1 - 9.8e-08 31.6 0.0 1.8e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Cas_Csy2 PF09614.5 EIE82377.1 - 0.037 13.2 0.1 0.056 12.6 0.1 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy2) PMM PF03332.8 EIE82378.1 - 2.8e-110 367.1 0.4 3.2e-110 366.9 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 EIE82378.1 - 3e-06 27.0 0.0 1.9e-05 24.4 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EIE82378.1 - 0.00037 19.8 0.0 0.093 12.0 0.0 2.0 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase TMPIT PF07851.8 EIE82378.1 - 0.11 11.5 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein Ribosomal_L18p PF00861.17 EIE82379.1 - 2.5e-32 111.5 0.5 3.9e-32 110.9 0.0 1.5 2 0 0 2 2 2 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 EIE82379.1 - 1.1e-30 106.0 2.8 1.5e-30 105.5 1.9 1.2 1 0 0 1 1 1 1 Ribosomal L18 C-terminal region SSF PF00474.12 EIE82380.1 - 2.4e-21 75.8 35.4 4.1e-21 75.1 24.6 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family RhoGEF PF00621.15 EIE82381.1 - 1.5e-43 148.7 3.5 3.6e-43 147.5 2.4 1.7 1 0 0 1 1 1 1 RhoGEF domain CDC24 PF06395.6 EIE82381.1 - 6.9e-29 99.7 0.1 2e-28 98.2 0.0 1.9 2 0 0 2 2 2 1 CDC24 Calponin PH_10 PF15411.1 EIE82381.1 - 1.2e-25 89.9 1.5 4.9e-25 87.9 0.6 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain PB1 PF00564.19 EIE82381.1 - 3e-15 55.6 0.2 3.5e-14 52.2 0.0 2.5 2 0 0 2 2 2 1 PB1 domain CH PF00307.26 EIE82381.1 - 0.095 12.7 0.9 0.35 10.9 0.1 2.4 2 0 0 2 2 2 0 Calponin homology (CH) domain MFS_1 PF07690.11 EIE82382.1 - 2e-47 161.6 19.6 2.6e-47 161.2 13.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIE82382.1 - 5.2e-13 48.3 11.4 9.9e-13 47.4 4.7 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.1 EIE82382.1 - 1.1e-08 33.9 11.2 0.00012 20.6 7.9 2.1 1 1 1 2 2 2 2 MFS/sugar transport protein MFS_3 PF05977.8 EIE82382.1 - 7.2e-07 27.6 4.0 9.2e-07 27.3 2.8 1.1 1 0 0 1 1 1 1 Transmembrane secretion effector DUF2104 PF09877.4 EIE82382.1 - 0.18 11.8 4.4 1.6 8.7 0.1 3.3 3 1 0 3 3 3 0 Predicted membrane protein (DUF2104) PI3Ka PF00613.15 EIE82383.1 - 3.1e-61 205.7 0.4 5.3e-61 205.0 0.3 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 EIE82383.1 - 1.8e-49 168.3 0.1 4.9e-48 163.6 0.0 2.8 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase DUF4135 PF13575.1 EIE82383.1 - 0.0022 17.0 0.0 0.011 14.7 0.0 2.0 2 1 0 2 2 2 1 Domain of unknown function (DUF4135) FlgM PF04316.8 EIE82383.1 - 0.005 16.7 0.7 0.013 15.4 0.5 1.7 1 0 0 1 1 1 1 Anti-sigma-28 factor, FlgM LON PF02190.11 EIE82384.1 - 4.3e-15 55.9 0.0 7.2e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain WD40 PF00400.27 EIE82385.1 - 1.2e-23 82.0 11.1 3.8e-06 26.5 0.0 8.6 9 0 0 9 9 9 5 WD domain, G-beta repeat Nup160 PF11715.3 EIE82385.1 - 0.00017 19.9 0.0 0.027 12.5 0.0 2.4 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Lactonase PF10282.4 EIE82385.1 - 0.005 15.9 0.0 1.4 7.8 0.0 2.7 2 0 0 2 2 2 2 Lactonase, 7-bladed beta-propeller DUF2992 PF11208.3 EIE82385.1 - 0.013 15.4 2.8 0.21 11.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2992) PRCC PF10253.4 EIE82386.1 - 5.4e-16 59.8 5.5 5.4e-16 59.8 3.8 3.0 1 1 1 3 3 3 1 Mitotic checkpoint regulator, MAD2B-interacting FHA PF00498.21 EIE82387.1 - 1.9e-14 53.5 0.1 3.8e-14 52.5 0.0 1.6 2 0 0 2 2 2 1 FHA domain zf-RING_2 PF13639.1 EIE82387.1 - 2.6e-09 36.7 11.7 5.4e-09 35.7 8.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EIE82387.1 - 0.00022 21.2 5.6 0.00022 21.2 3.9 1.9 2 0 0 2 2 2 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EIE82387.1 - 0.001 18.8 1.6 0.0019 18.0 1.1 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 EIE82387.1 - 0.0014 18.3 8.9 0.0041 16.8 6.2 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EIE82387.1 - 0.003 17.1 7.9 0.0068 16.0 5.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIE82387.1 - 0.005 16.4 10.6 0.012 15.2 7.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIE82387.1 - 0.013 15.5 12.7 0.03 14.3 8.8 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.7 EIE82387.1 - 0.074 12.2 0.5 0.12 11.5 0.4 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger PHD PF00628.24 EIE82387.1 - 0.3 10.8 6.7 0.67 9.7 4.7 1.6 1 0 0 1 1 1 0 PHD-finger Nol1_Nop2_Fmu PF01189.12 EIE82388.1 - 2.5e-37 128.8 0.0 5.5e-31 108.0 0.0 2.6 3 0 0 3 3 3 2 NOL1/NOP2/sun family FtsJ PF01728.14 EIE82388.1 - 0.043 13.8 0.0 0.12 12.3 0.0 1.8 1 0 0 1 1 1 0 FtsJ-like methyltransferase JmjN PF02375.12 EIE82388.1 - 0.81 9.2 4.8 0.48 9.9 1.0 2.1 2 0 0 2 2 2 0 jmjN domain SNF2_N PF00176.18 EIE82389.1 - 1.4e-46 158.6 0.1 2.3e-45 154.7 0.1 2.1 1 1 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EIE82389.1 - 1.4e-08 34.8 0.0 4e-08 33.3 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EIE82389.1 - 2.6e-06 27.2 0.0 6.6e-06 25.8 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EIE82389.1 - 5.9e-05 22.6 0.0 0.00023 20.7 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Lipoprotein_21 PF14041.1 EIE82389.1 - 0.17 11.8 0.0 0.39 10.6 0.0 1.5 1 0 0 1 1 1 0 LppP/LprE lipoprotein Pkinase PF00069.20 EIE82390.1 - 6.5e-50 169.7 0.0 1.4e-49 168.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE82390.1 - 2.5e-28 98.8 0.0 4.1e-28 98.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EIE82390.1 - 2.1e-06 26.9 0.0 4.5e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIE82390.1 - 5.9e-05 22.9 0.0 0.00017 21.4 0.0 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EIE82390.1 - 0.00058 18.9 0.0 0.00095 18.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like WaaY PF06176.6 EIE82390.1 - 0.0037 16.5 0.1 0.0065 15.7 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) YrbL-PhoP_reg PF10707.4 EIE82390.1 - 0.0046 16.3 0.0 0.01 15.2 0.0 1.5 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL EcKinase PF02958.15 EIE82390.1 - 0.014 14.5 0.0 0.028 13.5 0.0 1.5 1 0 0 1 1 1 0 Ecdysteroid kinase RIO1 PF01163.17 EIE82390.1 - 0.02 14.2 0.1 0.043 13.1 0.1 1.5 1 0 0 1 1 1 0 RIO1 family DDE_3 PF13358.1 EIE82392.1 - 3.1e-07 30.2 0.1 3.1e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE82393.1 - 2.3e-23 82.5 0.0 2.5e-22 79.2 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 EIE82393.1 - 2.2e-16 59.8 0.0 4.4e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE82393.1 - 2.7e-11 42.9 0.2 6.5e-11 41.7 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.1 EIE82393.1 - 3.3e-06 27.4 0.0 1.5e-05 25.3 0.0 2.3 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.12 EIE82393.1 - 8.6e-06 25.7 1.0 2.1e-05 24.4 0.0 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein UBN2_2 PF14227.1 EIE82393.1 - 3.6e-05 23.2 0.5 0.0011 18.5 0.1 3.5 4 1 0 4 4 4 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EIE82393.1 - 0.0007 19.3 0.7 0.26 11.0 0.1 2.9 3 0 0 3 3 3 2 gag-polypeptide of LTR copia-type gag-asp_proteas PF13975.1 EIE82393.1 - 0.0011 18.7 0.0 0.0022 17.7 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.5 EIE82393.1 - 0.0087 15.4 0.1 0.029 13.7 0.0 2.0 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger HTH_Tnp_Tc3_2 PF01498.13 EIE82394.1 - 2e-14 53.4 0.4 2.3e-14 53.2 0.3 1.1 1 0 0 1 1 1 1 Transposase DUF2026 PF09641.5 EIE82396.1 - 0.0075 15.6 0.1 0.013 14.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2026) DUF305 PF03713.8 EIE82396.1 - 0.023 14.4 1.7 0.035 13.9 0.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF305) DUF1631 PF07793.6 EIE82396.1 - 0.078 11.1 4.5 0.14 10.2 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) Chromo PF00385.19 EIE82397.1 - 4.3e-10 39.1 0.2 7.2e-10 38.3 0.1 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain HTH_Tnp_Tc3_2 PF01498.13 EIE82398.1 - 1.5e-07 31.3 0.7 1.5e-07 31.3 0.5 2.0 3 0 0 3 3 3 1 Transposase Retrotrans_gag PF03732.12 EIE82399.1 - 9.8e-10 38.3 0.1 2.2e-09 37.2 0.1 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein UBN2 PF14223.1 EIE82399.1 - 0.011 15.4 0.0 0.037 13.8 0.0 1.9 1 1 0 1 1 1 0 gag-polypeptide of LTR copia-type rve PF00665.21 EIE82400.1 - 1.6e-20 73.3 0.0 5.3e-20 71.7 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE82400.1 - 4.3e-11 42.5 0.4 1e-10 41.3 0.3 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE82400.1 - 1.4e-10 40.6 0.4 3.7e-10 39.3 0.3 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Transposase_21 PF02992.9 EIE82401.1 - 2.8e-08 33.1 1.5 7.8e-08 31.6 0.0 2.3 2 1 1 3 3 3 1 Transposase family tnp2 Mto2_bdg PF12808.2 EIE82402.1 - 0.87 9.7 7.7 4.6 7.4 0.2 3.4 3 0 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region NurA PF09376.5 EIE82404.1 - 0.034 13.6 0.5 0.039 13.4 0.3 1.2 1 0 0 1 1 1 0 NurA domain DUF4119 PF13494.1 EIE82404.1 - 0.15 12.0 2.2 0.29 11.1 0.7 2.0 1 1 1 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF4119) DDE_Tnp_IS1595 PF12762.2 EIE82405.1 - 1.1e-22 80.4 0.8 2e-22 79.6 0.3 1.6 2 0 0 2 2 2 1 ISXO2-like transposase domain HTH_Tnp_Tc3_2 PF01498.13 EIE82406.1 - 1.5e-08 34.5 0.4 1.5e-08 34.5 0.3 2.2 1 1 1 2 2 2 1 Transposase DDE_3 PF13358.1 EIE82406.1 - 1.2e-06 28.3 0.0 2.2e-06 27.4 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_29 PF13551.1 EIE82406.1 - 0.00079 19.5 1.7 0.0022 18.1 1.1 1.8 1 1 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_ISL3 PF13542.1 EIE82406.1 - 0.028 13.5 0.6 0.028 13.5 0.4 2.4 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 HTH_32 PF13565.1 EIE82406.1 - 0.073 13.8 0.8 0.18 12.6 0.5 1.7 1 0 0 1 1 1 0 Homeodomain-like domain HTH_12 PF08461.5 EIE82406.1 - 0.1 12.3 0.1 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain HTH_21 PF13276.1 EIE82406.1 - 0.14 12.2 1.7 0.93 9.5 0.0 2.4 2 0 0 2 2 2 0 HTH-like domain HTH_23 PF13384.1 EIE82406.1 - 0.25 11.0 2.9 2.7 7.7 0.2 2.5 2 0 0 2 2 2 0 Homeodomain-like domain DDE_3 PF13358.1 EIE82407.1 - 1e-19 70.7 0.2 1.9e-19 69.8 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE82407.1 - 2.6e-13 49.8 1.5 6.8e-13 48.4 0.8 1.9 2 0 0 2 2 2 1 Transposase Ku_PK_bind PF08785.6 EIE82407.1 - 0.005 16.7 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 Ku C terminal domain like rve PF00665.21 EIE82407.1 - 0.008 16.2 0.0 0.029 14.4 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain CG-1 PF03859.11 EIE82407.1 - 0.048 13.1 0.3 0.11 12.0 0.1 1.8 2 0 0 2 2 2 0 CG-1 domain Transposase_21 PF02992.9 EIE82408.1 - 1.3e-21 76.6 0.0 2.2e-21 76.0 0.0 1.2 1 0 0 1 1 1 1 Transposase family tnp2 DUF1258 PF06869.7 EIE82408.1 - 0.0026 16.8 0.0 0.0042 16.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) DDE_3 PF13358.1 EIE82409.1 - 1.3e-06 28.2 0.0 2.2e-06 27.4 0.0 1.4 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE82409.1 - 0.013 15.5 0.2 0.032 14.2 0.1 1.6 1 0 0 1 1 1 0 Transposase DUF1203 PF06718.6 EIE82410.1 - 0.083 12.7 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1203) Med15 PF09606.5 EIE82410.1 - 0.64 8.1 21.2 0.9 7.6 14.7 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DDE_Tnp_IS1595 PF12762.2 EIE82412.1 - 1e-11 44.8 0.0 9.1e-06 25.5 0.0 2.7 2 1 0 2 2 2 2 ISXO2-like transposase domain Rep_2 PF01719.12 EIE82413.1 - 0.061 12.8 2.0 0.1 12.0 1.4 1.3 1 0 0 1 1 1 0 Plasmid replication protein DUF4304 PF14137.1 EIE82413.1 - 0.16 12.0 1.4 0.25 11.4 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4304) DDE_3 PF13358.1 EIE82414.1 - 9.3e-10 38.4 2.1 3.4e-09 36.5 0.5 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE82415.1 - 1.7e-13 50.4 1.2 2.8e-13 49.7 0.8 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.1 EIE82415.1 - 0.0025 17.5 0.0 0.0047 16.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EIE82416.1 - 1e-15 57.7 0.0 2.1e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE82416.1 - 2e-09 37.3 0.6 1.1e-08 35.0 0.1 2.4 1 1 1 2 2 2 1 Transposase NUDIX_4 PF14815.1 EIE82416.1 - 0.014 14.7 0.3 0.027 13.9 0.2 1.5 1 0 0 1 1 1 0 NUDIX domain HTH_23 PF13384.1 EIE82416.1 - 0.044 13.4 0.0 0.099 12.3 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain GcrA PF07750.6 EIE82416.1 - 0.063 13.4 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 GcrA cell cycle regulator HTH_7 PF02796.10 EIE82416.1 - 0.066 13.0 0.1 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase Leader_Erm PF08253.6 EIE82417.1 - 0.33 10.4 0.3 0.33 10.4 0.2 2.1 2 0 0 2 2 2 0 Erm Leader peptide rve PF00665.21 EIE82418.1 - 3.7e-17 62.5 0.0 1.1e-16 60.9 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE82418.1 - 6.6e-12 45.2 0.3 1.8e-11 43.7 0.2 1.9 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 EIE82418.1 - 0.0042 17.5 0.0 0.02 15.3 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.1 EIE82418.1 - 0.017 14.9 0.0 0.034 13.9 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF2759 PF10958.3 EIE82418.1 - 0.33 10.5 1.1 0.8 9.3 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2759) HTH_Tnp_Tc3_2 PF01498.13 EIE82419.1 - 1.1e-09 38.1 1.1 2.7e-09 36.9 0.8 1.7 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.1 EIE82419.1 - 1.4e-08 34.5 0.0 2.8e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease FAM70 PF14967.1 EIE82419.1 - 0.014 14.6 0.0 0.02 14.0 0.0 1.2 1 0 0 1 1 1 0 FAM70 protein HTH_Tnp_4 PF13613.1 EIE82419.1 - 0.051 13.1 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease Lzipper-MIP1 PF14389.1 EIE82420.1 - 0.017 15.2 2.4 0.035 14.2 1.3 1.7 1 1 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 V_ATPase_I PF01496.14 EIE82420.1 - 0.067 11.0 1.3 0.069 11.0 0.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 EIE82420.1 - 0.19 11.2 1.9 0.25 10.9 1.3 1.3 1 0 0 1 1 1 0 IncA protein Phage_Mu_Gam PF07352.7 EIE82420.1 - 0.55 9.7 8.0 0.066 12.7 2.4 1.7 2 1 0 2 2 2 0 Bacteriophage Mu Gam like protein DUF972 PF06156.8 EIE82420.1 - 0.6 10.4 4.9 0.12 12.7 0.4 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF972) DDE_Tnp_IS1595 PF12762.2 EIE82422.1 - 7e-15 55.1 0.0 5.6e-09 35.9 0.0 2.7 1 1 1 2 2 2 2 ISXO2-like transposase domain DUF4218 PF13960.1 EIE82423.1 - 8.1e-06 25.3 0.2 1.4e-05 24.5 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) HTH_Tnp_Tc3_2 PF01498.13 EIE82424.1 - 7.7e-16 57.9 0.1 1.5e-15 56.9 0.1 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.1 EIE82424.1 - 4.6e-08 32.9 0.1 7e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_33 PF13592.1 EIE82424.1 - 1.8e-06 27.3 0.2 5.3e-06 25.8 0.0 1.9 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.1 EIE82424.1 - 1e-05 26.2 0.0 0.00032 21.4 0.0 2.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_21 PF13276.1 EIE82424.1 - 0.0009 19.2 0.0 0.0031 17.4 0.0 1.9 2 0 0 2 2 2 1 HTH-like domain HTH_29 PF13551.1 EIE82424.1 - 0.0013 18.8 0.0 0.0034 17.5 0.0 1.8 1 0 0 1 1 1 1 Winged helix-turn helix Acetyltransf_2 PF00797.12 EIE82424.1 - 0.045 13.3 0.2 8.5 5.8 0.1 2.5 2 1 1 3 3 3 0 N-acetyltransferase Transposase_21 PF02992.9 EIE82425.1 - 3.9e-23 81.7 0.1 3.9e-23 81.7 0.1 1.7 2 0 0 2 2 2 1 Transposase family tnp2 DDE_3 PF13358.1 EIE82427.1 - 7.7e-14 51.6 0.0 1.2e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE82427.1 - 0.00017 21.5 1.7 0.00086 19.3 0.1 2.4 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.1 EIE82427.1 - 0.0039 16.7 0.8 0.021 14.4 0.0 2.6 3 0 0 3 3 3 1 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.1 EIE82427.1 - 0.0071 15.5 0.2 0.019 14.1 0.2 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_28 PF13518.1 EIE82427.1 - 0.014 15.4 0.0 0.042 13.8 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_11 PF08279.7 EIE82427.1 - 0.087 12.4 0.1 0.23 11.1 0.1 1.7 1 0 0 1 1 1 0 HTH domain HTH_36 PF13730.1 EIE82427.1 - 0.42 10.7 2.9 1 9.5 0.1 2.7 2 1 1 3 3 3 0 Helix-turn-helix domain DDE_3 PF13358.1 EIE82428.1 - 1.3e-16 60.6 0.0 3.7e-16 59.2 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE82428.1 - 8.9e-09 35.2 0.7 2.5e-08 33.8 0.5 1.7 2 1 0 2 2 2 1 Transposase DDE_Tnp_IS1595 PF12762.2 EIE82429.1 - 1.4e-14 54.1 0.0 6.2e-09 35.8 0.0 2.8 2 1 0 2 2 2 2 ISXO2-like transposase domain HTH_38 PF13936.1 EIE82430.1 - 0.00011 21.7 0.0 0.00014 21.3 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.1 EIE82430.1 - 0.00024 20.6 0.0 0.00032 20.2 0.0 1.2 1 0 0 1 1 1 1 Homeodomain-like domain MarR PF01047.17 EIE82430.1 - 0.015 14.9 0.0 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 MarR family TetR_N PF00440.18 EIE82430.1 - 0.02 14.5 0.3 0.094 12.3 0.1 1.9 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family Fe_dep_repress PF01325.14 EIE82430.1 - 0.021 14.7 0.0 0.028 14.3 0.0 1.3 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain Sigma54_DBD PF04552.8 EIE82430.1 - 0.022 14.2 0.0 0.028 13.9 0.0 1.2 1 0 0 1 1 1 0 Sigma-54, DNA binding domain HTH_6 PF01418.12 EIE82430.1 - 0.038 13.7 0.0 0.056 13.1 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family HTH_Tnp_4 PF13613.1 EIE82430.1 - 0.053 13.0 0.1 0.088 12.3 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_28 PF13518.1 EIE82430.1 - 0.057 13.4 0.0 0.072 13.1 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain CENP-B_N PF04218.8 EIE82430.1 - 0.059 12.8 0.0 0.088 12.2 0.0 1.2 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain TrmB PF01978.14 EIE82430.1 - 0.063 12.9 0.0 0.094 12.4 0.0 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_5 PF01022.15 EIE82430.1 - 0.068 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family LacI PF00356.16 EIE82430.1 - 0.071 12.7 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family Phage_CII PF05269.6 EIE82430.1 - 0.071 13.1 0.0 0.098 12.6 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage CII protein Sigma70_r4_2 PF08281.7 EIE82430.1 - 0.073 12.5 0.1 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_3 PF01381.17 EIE82430.1 - 0.096 12.5 0.1 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix HTH_Tnp_1 PF01527.15 EIE82430.1 - 0.1 12.5 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Transposase HTH_29 PF13551.1 EIE82430.1 - 0.12 12.5 0.0 0.14 12.3 0.0 1.1 1 0 0 1 1 1 0 Winged helix-turn helix Terminase_5 PF06056.7 EIE82430.1 - 0.15 11.6 0.7 0.19 11.3 0.0 1.5 2 0 0 2 2 1 0 Putative ATPase subunit of terminase (gpP-like) DDE_3 PF13358.1 EIE82431.1 - 3.1e-11 43.2 3.2 4e-11 42.8 1.4 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_3 PF13358.1 EIE82432.1 - 5.2e-16 58.7 0.0 9.7e-16 57.8 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE82432.1 - 1.8e-11 43.9 0.4 5.4e-11 42.3 0.1 1.9 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 EIE82432.1 - 0.0042 17.2 0.2 0.0097 16.0 0.0 1.7 2 0 0 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.1 EIE82432.1 - 0.014 15.0 0.1 0.035 13.7 0.1 1.7 1 0 0 1 1 1 0 Homeodomain-like domain Exo_endo_phos_2 PF14529.1 EIE82433.1 - 9.6e-10 38.1 0.0 1.9e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EIE82433.1 - 9e-06 25.7 0.4 1.5e-05 25.0 0.3 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Dict-STAT-coil PF09267.5 EIE82433.1 - 0.00047 20.3 0.3 0.00082 19.5 0.2 1.3 1 0 0 1 1 1 1 Dictyostelium STAT, coiled coil zf-CCHC PF00098.18 EIE82434.1 - 1.8e-05 24.4 14.5 0.00026 20.7 1.9 3.5 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_6 PF15288.1 EIE82434.1 - 5.8e-05 22.6 3.9 0.058 13.0 0.7 2.7 2 0 0 2 2 2 2 Zinc knuckle NMD3 PF04981.8 EIE82434.1 - 0.051 12.6 2.7 0.062 12.4 0.5 1.8 2 0 0 2 2 2 0 NMD3 family zf-CCHC_4 PF14392.1 EIE82434.1 - 1.5 8.5 15.0 3 7.5 0.8 3.3 3 0 0 3 3 3 0 Zinc knuckle zf-C2H2_2 PF12756.2 EIE82435.1 - 0.0014 18.7 0.1 0.0016 18.5 0.1 1.1 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) DDE_3 PF13358.1 EIE82436.1 - 1.3e-22 80.1 0.6 2.4e-21 75.9 0.0 3.0 3 1 0 3 3 3 1 DDE superfamily endonuclease rve PF00665.21 EIE82436.1 - 0.0025 17.8 0.0 0.0088 16.1 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain ATP-grasp PF02222.17 EIE82436.1 - 0.097 12.0 0.1 0.23 10.7 0.0 1.6 2 0 0 2 2 2 0 ATP-grasp domain APC2 PF08672.6 EIE82436.1 - 0.15 12.3 0.6 7.1 6.9 0.2 2.4 2 0 0 2 2 2 0 Anaphase promoting complex (APC) subunit 2 Iso_dh PF00180.15 EIE82437.1 - 6.2e-100 334.5 0.0 7.2e-100 334.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase NUDIX PF00293.23 EIE82438.1 - 1.8e-13 50.3 0.0 2.2e-11 43.5 0.0 2.1 1 1 0 1 1 1 1 NUDIX domain Nipped-B_C PF12830.2 EIE82438.1 - 0.057 13.0 0.0 0.07 12.7 0.0 1.2 1 0 0 1 1 1 0 Sister chromatid cohesion C-terminus PMT PF02366.13 EIE82439.1 - 6.1e-51 173.1 26.4 2.8e-41 141.5 0.4 2.9 2 1 1 3 3 3 2 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EIE82439.1 - 2.8e-26 92.2 0.1 5.6e-26 91.2 0.1 1.5 1 0 0 1 1 1 1 MIR domain UBX PF00789.15 EIE82440.1 - 7.6e-19 67.5 0.0 3.4e-18 65.4 0.0 2.1 2 0 0 2 2 2 1 UBX domain Asp-B-Hydro_N PF05279.6 EIE82440.1 - 4.8 6.9 20.7 8.6 6.1 14.3 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region CAF-1_p150 PF11600.3 EIE82440.1 - 9.9 5.4 35.7 0.27 10.5 20.2 1.7 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal HTH_37 PF13744.1 EIE82441.1 - 0.086 12.6 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain RbcS PF12338.3 EIE82444.1 - 0.2 11.4 0.8 0.59 9.9 0.5 1.9 1 0 0 1 1 1 0 Ribulose-1,5-bisphosphate carboxylase small subunit Nramp PF01566.13 EIE82446.1 - 2.7e-10 39.6 1.9 3.2e-10 39.3 1.3 1.0 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein ArfGap PF01412.13 EIE82448.1 - 7.3e-05 22.5 0.8 0.00014 21.6 0.1 1.8 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf Lamp PF01299.12 EIE82448.1 - 0.36 9.9 4.3 0.61 9.1 3.0 1.3 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) zf-met2 PF12907.2 EIE82450.1 - 0.14 12.1 0.3 0.2 11.6 0.2 1.2 1 0 0 1 1 1 0 Zinc-binding Methyltransf_11 PF08241.7 EIE82451.1 - 7.2e-08 32.8 0.0 2.6e-07 31.0 0.0 1.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIE82451.1 - 0.0057 16.2 0.0 0.01 15.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIE82451.1 - 0.016 14.9 0.0 0.34 10.6 0.0 2.1 1 1 0 2 2 2 0 Methyltransferase domain Pkinase PF00069.20 EIE82455.1 - 7.6e-61 205.5 0.4 8.8e-61 205.3 0.3 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE82455.1 - 1.5e-20 73.3 0.0 2.1e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIE82455.1 - 1.4e-05 24.9 0.0 7.3e-05 22.6 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EIE82455.1 - 0.0044 16.6 0.0 0.0087 15.6 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 EIE82455.1 - 0.058 12.4 0.2 0.11 11.5 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EIE82455.1 - 0.071 12.4 0.4 0.18 11.1 0.3 1.5 1 1 0 1 1 1 0 RIO1 family CNH PF00780.17 EIE82456.1 - 1.1e-59 202.1 0.5 1e-57 195.6 0.0 3.1 3 0 0 3 3 3 1 CNH domain PH_5 PF15405.1 EIE82456.1 - 8.2e-39 132.6 0.1 3.1e-38 130.7 0.1 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 EIE82456.1 - 3.6e-35 121.4 0.1 8.9e-35 120.1 0.1 1.7 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.16 EIE82456.1 - 4.4e-13 48.7 0.0 1.1e-12 47.4 0.0 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Asparaginase PF00710.15 EIE82458.1 - 1.7e-118 395.0 0.0 2.2e-118 394.6 0.0 1.1 1 0 0 1 1 1 1 Asparaginase Ank_2 PF12796.2 EIE82458.1 - 5.5e-23 81.1 0.1 6.3e-16 58.5 0.1 2.6 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EIE82458.1 - 1.3e-15 57.4 1.2 1.3e-07 31.9 0.0 4.3 1 1 4 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.25 EIE82458.1 - 1.4e-15 56.1 2.8 1.1e-07 31.3 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 EIE82458.1 - 9.3e-15 54.3 0.7 4.3e-09 36.3 0.0 4.4 2 2 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIE82458.1 - 5e-11 41.7 3.6 0.00031 20.6 0.0 5.4 6 0 0 6 6 6 3 Ankyrin repeat zf-DNL PF05180.7 EIE82458.1 - 0.13 12.0 0.1 0.29 10.8 0.1 1.5 1 0 0 1 1 1 0 DNL zinc finger Med15_fungi PF05397.7 EIE82459.1 - 3.5e-25 88.2 0.7 3.5e-25 88.2 0.5 9.1 7 2 2 9 9 9 1 Mediator complex subunit 15 SRF-TF PF00319.13 EIE82460.1 - 2.1e-08 33.2 0.0 3.6e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Tcf25 PF04910.9 EIE82462.1 - 0.092 11.6 0.0 0.12 11.3 0.0 1.2 1 1 0 1 1 1 0 Transcriptional repressor TCF25 Cyt-b5 PF00173.23 EIE82469.1 - 7.5e-25 86.5 0.2 9.1e-25 86.2 0.1 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain PsbY PF06298.6 EIE82469.1 - 0.036 13.5 0.6 0.058 12.9 0.5 1.4 1 0 0 1 1 1 0 Photosystem II protein Y (PsbY) DUF1767 PF08585.7 EIE82471.1 - 0.00081 19.6 0.0 0.0029 17.8 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1767) zf-trcl PF13451.1 EIE82472.1 - 0.095 12.3 4.9 0.09 12.4 2.3 1.8 1 1 0 1 1 1 0 Probable zinc-binding domain zf-DBF PF07535.7 EIE82472.1 - 1.6 8.4 6.1 0.18 11.4 0.3 2.1 2 0 0 2 2 2 0 DBF zinc finger PH PF00169.24 EIE82473.1 - 0.0022 18.1 0.0 0.0092 16.1 0.0 2.1 1 0 0 1 1 1 1 PH domain PAN_4 PF14295.1 EIE82473.1 - 0.7 9.6 2.9 1.6 8.4 2.0 1.7 1 0 0 1 1 1 0 PAN domain DUF3250 PF11618.3 EIE82474.1 - 1.9e-05 24.7 0.0 5.9e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3250) DUF1771 PF08590.5 EIE82474.1 - 0.006 16.5 1.2 0.006 16.5 0.8 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF1771) RRM_1 PF00076.17 EIE82475.1 - 5.6e-08 32.3 0.0 1.1e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE82475.1 - 3.1e-06 27.0 0.0 6.2e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE82475.1 - 0.039 13.8 0.0 0.14 12.0 0.0 1.9 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ELMO_CED12 PF04727.8 EIE82478.1 - 1.5e-35 122.2 1.9 3.4e-35 121.0 1.3 1.6 1 0 0 1 1 1 1 ELMO/CED-12 family DUF3361 PF11841.3 EIE82478.1 - 1.5e-14 53.9 0.1 1.9e-13 50.4 0.1 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF3361) AdoHcyase PF05221.12 EIE82479.1 - 6.7e-140 464.6 0.0 7.7e-140 464.4 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 EIE82479.1 - 2.4e-87 290.8 3.3 3.5e-87 290.3 2.3 1.2 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 EIE82479.1 - 8.2e-10 38.1 0.1 1.7e-09 37.1 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 EIE82479.1 - 6.9e-06 25.5 0.2 1.1e-05 24.8 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 EIE82479.1 - 0.002 18.0 0.1 0.0042 17.0 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain TMEM107 PF14995.1 EIE82479.1 - 0.013 15.6 0.0 0.022 14.8 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein DUF4448 PF14610.1 EIE82479.1 - 0.14 11.6 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Ribosomal_S13 PF00416.17 EIE82480.1 - 3.8e-38 130.2 1.7 4.6e-38 129.9 1.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 EIE82480.1 - 0.0011 17.5 0.0 0.0013 17.4 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) DUF1822 PF08852.6 EIE82480.1 - 0.091 11.5 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1822) DUF1713 PF08213.6 EIE82481.1 - 7.9e-15 54.1 18.8 7.9e-15 54.1 13.1 1.5 2 0 0 2 2 2 1 Mitochondrial domain of unknown function (DUF1713) Glyco_hydro_47 PF01532.15 EIE82482.1 - 5.3e-112 374.7 1.1 5.9e-112 374.6 0.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF1680 PF07944.7 EIE82482.1 - 0.014 13.7 0.2 0.39 8.9 0.0 2.5 2 1 1 3 3 3 0 Putative glycosyl hydrolase of unknown function (DUF1680) FG-GAP PF01839.18 EIE82483.1 - 4.5e-15 54.8 1.0 2.3e-06 27.1 0.0 3.8 3 0 0 3 3 3 2 FG-GAP repeat VCBS PF13517.1 EIE82483.1 - 3.8e-11 43.1 1.3 2.1e-08 34.3 0.0 2.9 2 1 1 3 3 3 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP_2 PF14312.1 EIE82483.1 - 0.038 13.9 0.0 7.3 6.6 0.0 3.6 4 0 0 4 4 4 0 FG-GAP repeat TSP_3 PF02412.13 EIE82483.1 - 0.55 9.7 2.8 4.3 6.8 0.1 2.5 2 0 0 2 2 2 0 Thrombospondin type 3 repeat zf-H2C2_2 PF13465.1 EIE82484.1 - 8.5e-08 32.1 1.0 8.5e-08 32.1 0.7 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 EIE82484.1 - 2e-07 30.9 7.1 0.00046 20.3 1.2 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIE82484.1 - 5.8e-05 23.1 5.8 0.013 15.8 0.9 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EIE82484.1 - 0.0035 17.1 0.6 0.021 14.7 0.0 2.5 3 0 0 3 3 3 1 C2H2-type zinc finger DUF2635 PF10948.3 EIE82485.1 - 0.12 11.7 0.1 0.17 11.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2635) Myb_DNA-bind_6 PF13921.1 EIE82487.1 - 0.00018 21.5 0.5 0.0015 18.5 0.3 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain HTH_23 PF13384.1 EIE82487.1 - 0.00093 18.7 0.0 0.0025 17.3 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain Rap1_C PF11626.3 EIE82487.1 - 0.012 15.5 0.4 0.028 14.2 0.1 1.8 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-binding PF00249.26 EIE82487.1 - 0.017 15.1 1.5 0.058 13.4 1.0 2.0 1 1 0 1 1 1 0 Myb-like DNA-binding domain HTH_Crp_2 PF13545.1 EIE82487.1 - 0.11 12.3 0.0 0.95 9.3 0.0 2.4 3 0 0 3 3 3 0 Crp-like helix-turn-helix domain Bud13 PF09736.4 EIE82487.1 - 0.16 12.2 4.7 0.24 11.6 3.2 1.2 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Complex1_LYR PF05347.10 EIE82488.1 - 7.9e-11 41.5 2.5 1.3e-10 40.9 1.7 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EIE82488.1 - 1.9e-08 34.3 1.6 2.6e-08 33.9 1.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like mIF3 PF14877.1 EIE82488.1 - 0.056 12.7 0.6 0.067 12.5 0.4 1.2 1 0 0 1 1 1 0 Mitochondrial translation initiation factor Cupin_4 PF08007.7 EIE82488.1 - 0.078 12.1 0.2 0.096 11.9 0.1 1.1 1 0 0 1 1 1 0 Cupin superfamily protein MMTV_SAg PF01054.12 EIE82490.1 - 0.073 11.9 0.0 0.077 11.8 0.0 1.1 1 0 0 1 1 1 0 Mouse mammary tumour virus superantigen Pox_I3 PF04661.7 EIE82490.1 - 0.078 11.7 0.0 0.09 11.5 0.0 1.1 1 0 0 1 1 1 0 Poxvirus I3 ssDNA-binding protein DUF676 PF05057.9 EIE82491.1 - 1.3e-12 47.5 0.1 3.4e-06 26.5 0.0 2.4 1 1 1 2 2 2 2 Putative serine esterase (DUF676) PCI_Csn8 PF10075.4 EIE82492.1 - 1.7e-27 95.9 0.8 2.7e-27 95.2 0.5 1.3 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 EIE82492.1 - 7.8e-19 68.0 2.8 2.6e-18 66.3 2.0 1.7 1 1 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family DUF4487 PF14868.1 EIE82492.1 - 0.011 14.4 0.3 0.015 14.0 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4487) PCI PF01399.22 EIE82492.1 - 0.038 14.3 0.1 0.15 12.4 0.0 2.0 2 0 0 2 2 2 0 PCI domain DUF3355 PF11835.3 EIE82493.1 - 0.21 11.4 2.4 0.42 10.3 1.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3355) RGS PF00615.14 EIE82496.1 - 4.6e-24 84.7 0.6 1.1e-23 83.5 0.1 2.0 2 0 0 2 2 2 1 Regulator of G protein signaling domain DEP PF00610.16 EIE82496.1 - 0.006 16.3 0.1 0.013 15.1 0.1 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) L27 PF02828.11 EIE82496.1 - 0.014 15.0 0.1 0.063 12.9 0.0 2.1 2 0 0 2 2 2 0 L27 domain DJ-1_PfpI PF01965.19 EIE82497.1 - 5.4e-21 74.5 0.0 1.1e-20 73.5 0.0 1.5 1 1 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 EIE82497.1 - 0.0004 19.8 0.0 0.0014 18.1 0.0 2.0 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family EF-hand_4 PF12763.2 EIE82498.1 - 2.6e-40 136.3 0.0 2.4e-15 56.1 0.0 4.6 4 0 0 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 EIE82498.1 - 2.7e-08 33.8 3.4 0.011 15.8 0.0 4.1 4 1 0 4 4 3 2 EF-hand domain pair EF-hand_1 PF00036.27 EIE82498.1 - 4.5e-07 28.7 5.0 0.67 9.3 0.0 5.7 7 0 0 7 7 7 3 EF hand UBA PF00627.26 EIE82498.1 - 6e-06 25.9 0.1 1.4e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_8 PF13833.1 EIE82498.1 - 0.00081 18.9 0.0 0.45 10.1 0.0 3.7 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.1 EIE82498.1 - 0.0018 18.0 4.2 26 5.0 0.0 5.9 6 0 0 6 6 6 0 EF-hand domain Myosin_tail_1 PF01576.14 EIE82498.1 - 0.12 10.0 31.0 0.19 9.4 21.5 1.2 1 0 0 1 1 1 0 Myosin tail CENP-F_leu_zip PF10473.4 EIE82498.1 - 0.87 9.4 29.1 3.3 7.5 9.4 2.5 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tropomyosin_1 PF12718.2 EIE82498.1 - 1.2 8.9 28.1 1.1 9.0 11.8 2.7 1 1 1 2 2 2 0 Tropomyosin like Sec8_exocyst PF04048.9 EIE82498.1 - 1.5 8.4 15.3 0.41 10.2 1.2 2.5 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain Tup_N PF08581.5 EIE82498.1 - 2.1 8.6 16.0 6.7 6.9 3.8 3.2 2 1 0 2 2 2 0 Tup N-terminal Reo_sigmaC PF04582.7 EIE82498.1 - 2.6 7.1 14.4 0.31 10.1 3.7 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein IncA PF04156.9 EIE82498.1 - 3.5 7.1 25.6 0.42 10.1 12.9 2.4 1 1 1 2 2 2 0 IncA protein DUF4407 PF14362.1 EIE82498.1 - 5 5.9 20.5 14 4.5 14.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DDE_3 PF13358.1 EIE82499.1 - 5.9e-14 52.0 0.3 2.3e-13 50.0 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease DUF1219 PF06755.7 EIE82499.1 - 0.13 11.7 0.0 0.63 9.5 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1219) DDE_3 PF13358.1 EIE82500.1 - 6.9e-18 64.7 0.0 4.9e-10 39.3 0.0 3.0 3 0 0 3 3 3 2 DDE superfamily endonuclease HTH_28 PF13518.1 EIE82500.1 - 0.00017 21.5 1.1 0.00028 20.8 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.1 EIE82500.1 - 0.00088 18.8 0.9 0.0014 18.2 0.0 1.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.1 EIE82500.1 - 0.0042 17.2 0.0 0.0088 16.1 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_1 PF01527.15 EIE82500.1 - 0.043 13.7 0.6 0.075 12.9 0.1 1.7 1 1 0 1 1 1 0 Transposase HTH_17 PF12728.2 EIE82500.1 - 0.11 12.7 0.0 0.27 11.5 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain RabGAP-TBC PF00566.13 EIE82502.1 - 2e-49 167.9 0.1 3.6e-49 167.1 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_6 PF13405.1 EIE82502.1 - 0.0062 16.3 0.7 0.035 13.9 0.2 2.4 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.27 EIE82502.1 - 0.059 12.7 3.0 0.045 13.0 0.6 2.1 2 0 0 2 2 2 0 EF hand BTB_2 PF02214.17 EIE82503.1 - 5e-16 58.6 0.7 9e-16 57.8 0.1 1.7 2 0 0 2 2 2 1 BTB/POZ domain BTB PF00651.26 EIE82503.1 - 0.0017 18.3 0.0 0.0033 17.3 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain ABC_tran PF00005.22 EIE82504.1 - 3e-45 153.8 0.0 6.3e-23 81.5 0.0 3.9 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EIE82504.1 - 7.3e-15 55.6 0.5 0.00086 19.3 0.0 4.4 2 2 1 3 3 3 3 AAA domain SMC_N PF02463.14 EIE82504.1 - 1.9e-13 50.1 0.0 0.012 14.8 0.0 4.4 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EIE82504.1 - 1.3e-08 35.7 0.3 0.001 19.9 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_28 PF13521.1 EIE82504.1 - 4.4e-08 33.2 0.1 0.017 15.0 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EIE82504.1 - 8.1e-08 31.6 0.0 0.011 15.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 EIE82504.1 - 2.5e-07 30.9 0.0 0.017 15.2 0.0 4.0 5 0 0 5 5 4 2 AAA domain DUF258 PF03193.11 EIE82504.1 - 3.9e-07 29.3 0.0 0.0015 17.7 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA PF00004.24 EIE82504.1 - 4.6e-07 30.1 0.1 0.049 13.8 0.0 4.2 4 0 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 EIE82504.1 - 1.8e-06 27.9 0.0 0.015 15.2 0.0 3.1 2 0 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 EIE82504.1 - 1.9e-06 28.3 0.0 0.12 12.9 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein AAA_15 PF13175.1 EIE82504.1 - 2.7e-06 26.7 0.0 0.47 9.4 0.0 3.6 3 0 0 3 3 3 2 AAA ATPase domain SbcCD_C PF13558.1 EIE82504.1 - 4e-06 26.6 0.0 0.0094 15.8 0.0 3.5 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit NACHT PF05729.7 EIE82504.1 - 6.2e-06 25.9 0.2 0.048 13.3 0.0 3.5 4 0 0 4 4 3 2 NACHT domain ArgK PF03308.11 EIE82504.1 - 1.1e-05 24.4 0.1 0.048 12.4 0.0 2.5 2 0 0 2 2 2 2 ArgK protein RNA_helicase PF00910.17 EIE82504.1 - 1.5e-05 25.0 0.0 0.26 11.4 0.0 2.9 2 0 0 2 2 2 2 RNA helicase MobB PF03205.9 EIE82504.1 - 1.9e-05 24.3 0.0 0.14 11.8 0.0 3.1 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B Chromo PF00385.19 EIE82504.1 - 4e-05 23.1 2.1 5.6e-05 22.7 0.1 2.2 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_16 PF13191.1 EIE82504.1 - 4.5e-05 23.5 0.6 0.059 13.3 0.0 3.2 3 1 0 3 3 2 1 AAA ATPase domain AAA_18 PF13238.1 EIE82504.1 - 4.8e-05 23.6 0.1 0.14 12.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EIE82504.1 - 7.5e-05 22.6 0.0 0.38 10.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain DUF815 PF05673.8 EIE82504.1 - 8.2e-05 21.6 0.0 0.18 10.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_10 PF12846.2 EIE82504.1 - 0.00012 21.6 0.0 0.51 9.7 0.0 3.2 4 0 0 4 4 3 2 AAA-like domain AAA_14 PF13173.1 EIE82504.1 - 0.00014 21.7 0.0 0.13 12.1 0.0 3.1 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 EIE82504.1 - 0.00027 20.5 0.1 1.7 8.1 0.0 3.7 3 0 0 3 3 3 1 AAA domain AAA_23 PF13476.1 EIE82504.1 - 0.00033 21.0 9.5 0.14 12.5 0.6 3.5 3 1 0 3 3 3 2 AAA domain PduV-EutP PF10662.4 EIE82504.1 - 0.00043 19.7 0.0 0.64 9.4 0.0 2.9 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Zeta_toxin PF06414.7 EIE82504.1 - 0.00066 18.8 0.6 2.6 7.0 0.0 3.4 3 0 0 3 3 3 1 Zeta toxin HEAT_2 PF13646.1 EIE82504.1 - 0.0009 19.4 3.5 5.5 7.3 0.7 3.9 1 1 4 5 5 5 0 HEAT repeats ATP-synt_ab PF00006.20 EIE82504.1 - 0.00098 18.6 0.0 0.23 10.9 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain Arch_ATPase PF01637.13 EIE82504.1 - 0.0018 18.0 0.0 0.83 9.2 0.0 3.0 2 0 0 2 2 2 1 Archaeal ATPase AAA_13 PF13166.1 EIE82504.1 - 0.0022 16.5 0.5 3.4 6.0 0.0 3.5 4 0 0 4 4 4 1 AAA domain Dynamin_N PF00350.18 EIE82504.1 - 0.0024 17.7 0.1 0.5 10.1 0.0 2.9 3 0 0 3 3 2 1 Dynamin family AAA_5 PF07728.9 EIE82504.1 - 0.0081 15.8 0.1 5.6 6.6 0.0 3.8 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EIE82504.1 - 0.0087 15.4 0.0 5.4 6.3 0.0 3.4 4 0 0 4 4 4 0 AAA domain DUF87 PF01935.12 EIE82504.1 - 0.012 15.4 4.0 0.61 9.8 0.0 3.5 4 0 0 4 4 2 0 Domain of unknown function DUF87 Viral_helicase1 PF01443.13 EIE82504.1 - 0.017 14.6 0.0 0.41 10.1 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase PRK PF00485.13 EIE82504.1 - 0.024 14.2 0.0 2.8 7.4 0.0 2.9 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family MutS_V PF00488.16 EIE82504.1 - 0.025 13.9 0.1 5.1 6.4 0.0 2.3 2 0 0 2 2 2 0 MutS domain V FtsK_SpoIIIE PF01580.13 EIE82504.1 - 0.039 13.4 0.0 23 4.3 0.0 3.4 3 0 0 3 3 3 0 FtsK/SpoIIIE family Vac14_Fab1_bd PF12755.2 EIE82504.1 - 0.072 13.4 0.0 12 6.4 0.0 2.7 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region HEAT PF02985.17 EIE82504.1 - 0.87 9.8 7.5 3.3 8.0 0.0 4.3 5 0 0 5 5 2 0 HEAT repeat HSP70 PF00012.15 EIE82505.1 - 1.3e-263 875.4 13.5 1.5e-263 875.2 9.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EIE82505.1 - 3.6e-14 52.0 4.9 3.1e-12 45.7 1.0 2.6 2 1 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 EIE82505.1 - 0.0011 18.6 0.0 0.0024 17.5 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 EIE82505.1 - 0.0012 18.7 8.2 0.69 9.7 0.0 4.5 3 2 0 3 3 3 2 Cell division protein FtsA Phage_GP20 PF06810.6 EIE82505.1 - 0.0054 16.1 6.5 0.0054 16.1 4.5 1.9 2 0 0 2 2 2 1 Phage minor structural protein GP20 Hydantoinase_A PF01968.13 EIE82505.1 - 0.078 12.0 0.1 0.078 12.0 0.1 2.8 4 0 0 4 4 4 0 Hydantoinase/oxoprolinase HR1 PF02185.11 EIE82505.1 - 0.84 9.4 6.7 0.45 10.2 2.6 2.1 2 0 0 2 2 2 0 Hr1 repeat CR6_interact PF10147.4 EIE82506.1 - 0.00036 19.9 5.4 0.00065 19.0 3.7 1.4 1 0 0 1 1 1 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 DIOX_N PF14226.1 EIE82507.1 - 3.2e-19 69.5 0.1 5.4e-19 68.8 0.1 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EIE82507.1 - 6.4e-19 68.0 0.0 1.3e-18 67.1 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CAT_RBD PF03123.10 EIE82507.1 - 0.098 12.3 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 CAT RNA binding domain Mem_trans PF03547.13 EIE82508.1 - 1.6e-44 151.7 13.1 2e-44 151.4 9.1 1.1 1 0 0 1 1 1 1 Membrane transport protein Dynein_light PF01221.13 EIE82508.1 - 1.4e-31 108.3 1.5 3e-31 107.2 1.0 1.5 1 0 0 1 1 1 1 Dynein light chain type 1 DSPc PF00782.15 EIE82509.1 - 7.1e-16 57.9 0.0 1.2e-10 41.0 0.0 2.8 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain BCL9 PF11502.3 EIE82509.1 - 0.037 13.5 0.0 0.078 12.5 0.0 1.5 1 0 0 1 1 1 0 B-cell lymphoma 9 protein Homeobox_KN PF05920.6 EIE82511.1 - 1.5e-18 66.2 1.1 1.5e-18 66.2 0.7 2.1 2 0 0 2 2 2 1 Homeobox KN domain Homeobox PF00046.24 EIE82511.1 - 7.3e-09 35.1 0.2 3.1e-08 33.1 0.3 2.0 2 0 0 2 2 2 1 Homeobox domain NUDIX PF00293.23 EIE82512.1 - 1.5e-07 31.1 0.0 2.8e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain MIP-T3 PF10243.4 EIE82512.1 - 0.024 13.1 70.5 0.031 12.7 48.9 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 PLRV_ORF5 PF01690.12 EIE82512.1 - 0.84 8.7 31.6 1.1 8.3 21.9 1.3 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DDE_3 PF13358.1 EIE82513.1 - 5.9e-17 61.7 0.1 1.3e-16 60.6 0.1 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 EIE82513.1 - 1.6e-09 37.8 0.0 4.1e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.1 EIE82513.1 - 1.3e-06 29.1 0.4 2e-05 25.2 0.0 2.9 3 1 0 3 3 3 1 Homeodomain-like domain HTH_23 PF13384.1 EIE82513.1 - 2.6e-05 23.6 0.0 7.4e-05 22.2 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.1 EIE82513.1 - 3.3e-05 23.7 0.0 8.9e-05 22.4 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_1 PF01527.15 EIE82513.1 - 0.00051 19.9 0.6 0.0013 18.6 0.1 2.0 2 1 0 2 2 1 1 Transposase TrmB PF01978.14 EIE82513.1 - 0.002 17.7 0.1 0.0047 16.5 0.0 1.6 1 1 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_psq PF05225.11 EIE82513.1 - 0.017 14.6 0.0 0.048 13.2 0.0 1.7 1 0 0 1 1 1 0 helix-turn-helix, Psq domain HTH_17 PF12728.2 EIE82513.1 - 0.024 14.8 0.1 0.12 12.6 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.13 EIE82513.1 - 0.03 14.3 0.2 0.3 11.1 0.0 2.7 3 0 0 3 3 3 0 Transposase HTH_IclR PF09339.5 EIE82513.1 - 0.06 12.9 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_3 PF01381.17 EIE82513.1 - 0.15 11.9 0.2 0.38 10.6 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix MbeB_N PF04837.7 EIE82513.1 - 0.32 11.1 1.8 0.95 9.6 1.2 1.8 1 0 0 1 1 1 0 MbeB-like, N-term conserved region UDPG_MGDP_dh_N PF03721.9 EIE82514.1 - 1.2e-61 207.3 0.1 3.5e-61 205.8 0.0 1.8 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.10 EIE82514.1 - 1.5e-35 121.5 0.7 3.4e-34 117.1 0.2 2.7 3 0 0 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.14 EIE82514.1 - 6e-31 106.5 0.0 1.6e-30 105.1 0.0 1.8 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_Gly3P_dh_N PF01210.18 EIE82514.1 - 2e-05 24.3 0.2 0.058 13.1 0.0 2.6 2 0 0 2 2 2 2 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.10 EIE82514.1 - 0.00045 20.0 0.1 0.065 13.0 0.0 2.9 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AAA-ATPase_like PF09820.4 EIE82514.1 - 0.0023 17.1 0.5 0.0038 16.4 0.3 1.2 1 0 0 1 1 1 1 Predicted AAA-ATPase Ldh_1_N PF00056.18 EIE82514.1 - 0.011 15.6 0.2 6.6 6.5 0.0 2.9 2 1 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 EIE82514.1 - 0.022 14.4 0.4 0.58 9.7 0.0 2.8 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 EIE82514.1 - 0.1 11.5 0.1 0.27 10.1 0.0 1.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase DUF4608 PF15381.1 EIE82514.1 - 0.16 12.1 1.0 0.34 11.0 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4608) PP2C PF00481.16 EIE82515.1 - 4e-06 26.4 0.0 4.5e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EIE82515.1 - 0.002 17.5 0.0 0.002 17.5 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EIE82515.1 - 0.071 12.8 0.0 0.086 12.5 0.0 1.0 1 0 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) DUF479 PF04336.7 EIE82516.1 - 0.028 14.5 0.2 0.7 10.0 0.0 3.0 3 1 0 3 3 3 0 Protein of unknown function, DUF479 SRP_SPB PF02978.14 EIE82516.1 - 0.031 14.5 0.0 0.084 13.1 0.0 1.8 2 0 0 2 2 2 0 Signal peptide binding domain Gar1 PF04410.9 EIE82517.1 - 2.5e-40 137.4 5.4 2.5e-40 137.4 3.7 2.3 1 1 1 2 2 2 1 Gar1/Naf1 RNA binding region DUF3997 PF13162.1 EIE82517.1 - 0.12 12.2 0.1 0.16 11.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3997) Ribosomal_S6 PF01250.12 EIE82519.1 - 1.9e-15 56.4 0.0 2.3e-15 56.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 MYT1 PF08474.6 EIE82520.1 - 2.1 7.7 7.9 0.17 11.3 0.5 2.0 1 1 1 2 2 2 0 Myelin transcription factor 1 Ribosomal_L32e PF01655.13 EIE82521.1 - 2.3e-47 159.5 1.5 2.8e-47 159.3 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 Mito_carr PF00153.22 EIE82522.1 - 3.8e-27 93.8 7.9 2.4e-11 43.1 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Cyclin PF08613.6 EIE82523.1 - 2.1e-20 73.6 0.3 2.6e-20 73.3 0.2 1.2 1 0 0 1 1 1 1 Cyclin WD40 PF00400.27 EIE82524.1 - 5.3e-27 92.6 0.6 1.3e-11 43.9 0.0 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat eIF2A PF08662.6 EIE82524.1 - 5e-05 23.0 0.0 0.33 10.6 0.0 2.3 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A bZIP_1 PF00170.16 EIE82524.1 - 0.00072 19.4 1.1 0.0013 18.6 0.8 1.4 1 0 0 1 1 1 1 bZIP transcription factor DUF972 PF06156.8 EIE82524.1 - 0.007 16.7 0.0 0.11 12.8 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF972) Nup160 PF11715.3 EIE82524.1 - 0.016 13.3 0.1 3 5.8 0.0 2.4 1 1 0 2 2 2 0 Nucleoporin Nup120/160 DivIC PF04977.10 EIE82524.1 - 0.02 14.3 1.7 0.037 13.5 1.2 1.3 1 0 0 1 1 1 0 Septum formation initiator MIF PF01187.13 EIE82526.1 - 1.8e-17 63.4 0.0 2e-17 63.3 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Tautomerase PF01361.16 EIE82526.1 - 0.0019 17.7 0.0 0.85 9.2 0.0 2.1 2 0 0 2 2 2 2 Tautomerase enzyme NMU PF02070.10 EIE82526.1 - 0.11 12.0 0.1 0.27 10.8 0.1 1.6 1 0 0 1 1 1 0 Neuromedin U DPBB_1 PF03330.13 EIE82527.1 - 7.3e-13 48.3 1.8 1e-12 47.8 0.0 2.0 2 0 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Ribosomal_L35Ae PF01247.13 EIE82527.1 - 0.062 13.0 0.0 0.062 13.0 0.0 2.2 2 0 0 2 2 2 0 Ribosomal protein L35Ae Rpn3_C PF08375.6 EIE82527.1 - 0.17 12.2 1.2 0.27 11.6 0.9 1.2 1 0 0 1 1 1 0 Proteasome regulatory subunit C-terminal DUF3464 PF11947.3 EIE82527.1 - 2.6 7.5 7.5 3.4 7.1 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) BK_channel_a PF03493.13 EIE82529.1 - 0.037 13.9 0.2 0.085 12.8 0.1 1.5 1 0 0 1 1 1 0 Calcium-activated BK potassium channel alpha subunit Spc97_Spc98 PF04130.8 EIE82530.1 - 2.8e-25 88.6 15.5 4.8e-25 87.8 10.7 1.4 1 1 0 1 1 1 1 Spc97 / Spc98 family BPS PF08947.5 EIE82530.1 - 0.13 11.8 0.3 0.3 10.7 0.2 1.6 1 0 0 1 1 1 0 BPS (Between PH and SH2) DUF2413 PF10310.4 EIE82531.1 - 9.4e-28 97.1 0.0 1.3e-27 96.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2413) Tim17 PF02466.14 EIE82532.1 - 4.7e-06 26.6 0.3 1.3e-05 25.1 0.0 1.9 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family MAT1 PF06391.8 EIE82532.1 - 0.03 13.8 0.0 0.045 13.3 0.0 1.2 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 FGase PF05013.7 EIE82532.1 - 0.065 13.1 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 N-formylglutamate amidohydrolase Fork_head PF00250.13 EIE82533.1 - 1.3e-33 114.8 0.3 2.2e-33 114.1 0.2 1.3 1 0 0 1 1 1 1 Fork head domain YABBY PF04690.8 EIE82533.1 - 0.0074 16.5 0.5 0.014 15.6 0.4 1.5 1 0 0 1 1 1 1 YABBY protein Mg_trans_NIPA PF05653.9 EIE82534.1 - 9.1e-81 271.1 21.3 4e-79 265.6 14.8 2.0 1 1 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 EIE82534.1 - 2.9e-06 27.4 6.2 2.9e-06 27.4 4.3 2.9 2 1 0 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 EIE82534.1 - 1.5e-05 25.0 7.0 1.5e-05 25.0 4.9 3.0 3 1 0 3 3 3 1 EamA-like transporter family DUF914 PF06027.7 EIE82534.1 - 1.7 7.3 19.2 10 4.8 13.3 1.9 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF914) DUF2301 PF10063.4 EIE82534.1 - 3.6 7.7 17.2 0.46 10.6 4.8 2.4 1 1 0 2 2 2 0 Uncharacterized integral membrane protein (DUF2301) PH PF00169.24 EIE82535.1 - 2.3e-07 30.9 2.4 5.9e-07 29.6 0.0 2.6 2 1 0 2 2 2 1 PH domain Cofilin_ADF PF00241.15 EIE82535.1 - 0.0002 21.2 0.1 0.00066 19.5 0.0 1.9 2 0 0 2 2 2 1 Cofilin/tropomyosin-type actin-binding protein PH_11 PF15413.1 EIE82535.1 - 0.0026 17.9 0.2 0.023 14.9 0.0 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain CDK5_activator PF03261.10 EIE82535.1 - 2 7.6 13.1 0.56 9.4 6.8 1.6 1 1 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein DDE_3 PF13358.1 EIE82536.1 - 9.1e-27 93.6 0.0 3.8e-26 91.5 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_29 PF13551.1 EIE82536.1 - 1.1e-07 31.9 0.0 5.4e-07 29.7 0.0 2.0 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.1 EIE82536.1 - 1.4e-06 29.0 0.0 5.2e-06 27.1 0.0 2.1 2 0 0 2 2 1 1 Homeodomain-like domain HTH_23 PF13384.1 EIE82536.1 - 6.7e-06 25.5 0.9 0.00021 20.8 0.0 2.9 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.1 EIE82536.1 - 9e-05 22.3 1.3 0.0014 18.5 0.0 3.0 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_17 PF12728.2 EIE82536.1 - 0.00062 19.9 0.0 0.11 12.8 0.0 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_1 PF01527.15 EIE82536.1 - 0.0019 18.1 0.9 0.0057 16.5 0.1 2.0 2 0 0 2 2 2 1 Transposase rve PF00665.21 EIE82536.1 - 0.0024 17.9 0.0 0.012 15.6 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain HTH_Tnp_ISL3 PF13542.1 EIE82536.1 - 0.0054 15.8 0.1 0.01 15.0 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_30 PF13556.1 EIE82536.1 - 0.008 15.7 0.5 0.022 14.3 0.1 1.9 2 0 0 2 2 2 1 PucR C-terminal helix-turn-helix domain DUF1804 PF08822.6 EIE82536.1 - 0.059 13.1 0.0 0.2 11.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1804) Thioredoxin_2 PF13098.1 EIE82536.1 - 0.12 12.6 0.1 0.78 9.9 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin-like domain NADase_NGA PF07461.6 EIE82537.1 - 0.15 10.7 0.0 0.19 10.3 0.0 1.1 1 0 0 1 1 1 0 Nicotine adenine dinucleotide glycohydrolase (NADase) DDE_3 PF13358.1 EIE82539.1 - 1.4e-29 102.7 0.0 5.1e-29 100.9 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_29 PF13551.1 EIE82539.1 - 1.3e-07 31.7 0.0 6.6e-07 29.4 0.0 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.1 EIE82539.1 - 1.9e-06 28.5 0.0 6.3e-06 26.9 0.0 2.0 2 0 0 2 2 1 1 Homeodomain-like domain HTH_23 PF13384.1 EIE82539.1 - 1.1e-05 24.8 1.1 0.00024 20.6 0.0 2.9 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.1 EIE82539.1 - 0.00015 21.7 1.3 0.0017 18.3 0.0 2.8 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_17 PF12728.2 EIE82539.1 - 0.00083 19.5 0.0 0.12 12.5 0.0 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain rve PF00665.21 EIE82539.1 - 0.0015 18.6 0.0 0.0066 16.5 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain HTH_Tnp_1 PF01527.15 EIE82539.1 - 0.0023 17.8 0.9 0.0067 16.3 0.1 2.0 2 0 0 2 2 2 1 Transposase HTH_Tnp_ISL3 PF13542.1 EIE82539.1 - 0.0059 15.7 0.1 0.012 14.8 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_30 PF13556.1 EIE82539.1 - 0.01 15.4 0.5 0.025 14.1 0.1 1.9 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain DDE_1 PF03184.14 EIE82539.1 - 0.017 14.2 0.1 0.33 10.0 0.0 2.4 2 0 0 2 2 2 0 DDE superfamily endonuclease DUF1804 PF08822.6 EIE82539.1 - 0.062 13.0 0.1 0.23 11.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1804) zf-RVT PF13966.1 EIE82540.1 - 6e-06 26.4 2.0 1.1e-05 25.6 0.7 2.0 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase TP_methylase PF00590.15 EIE82541.1 - 1.6e-43 148.8 0.0 2.3e-43 148.3 0.0 1.2 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.1 EIE82541.1 - 8.3e-28 96.6 0.1 2.8e-27 94.9 0.0 1.9 2 0 0 2 2 2 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 EIE82541.1 - 2.4e-13 49.1 0.6 4.8e-13 48.2 0.4 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 EIE82541.1 - 3e-10 38.8 0.0 5.8e-10 37.9 0.0 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central DUF2761 PF10959.3 EIE82541.1 - 0.16 11.6 0.0 0.34 10.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2761) AA_kinase PF00696.23 EIE82543.1 - 2.4e-25 89.4 0.0 4.4e-25 88.6 0.0 1.5 1 0 0 1 1 1 1 Amino acid kinase family ACT_7 PF13840.1 EIE82543.1 - 3.6e-10 39.2 2.3 1.8e-08 33.7 0.5 2.6 2 0 0 2 2 2 2 ACT domain ACT PF01842.20 EIE82543.1 - 5e-10 38.6 0.3 5.3e-07 28.9 0.0 2.6 2 0 0 2 2 2 2 ACT domain Histone PF00125.19 EIE82544.1 - 9.3e-32 108.9 0.4 1.4e-31 108.3 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EIE82544.1 - 7.3e-06 26.0 0.0 1.1e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EIE82544.1 - 0.0015 18.5 0.1 0.0029 17.6 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EIE82544.1 - 0.0035 17.0 0.1 0.0064 16.1 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated CENP-T PF15511.1 EIE82544.1 - 0.14 11.3 1.3 0.29 10.3 0.9 1.6 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T Asp PF00026.18 EIE82545.1 - 2.8e-36 125.3 0.4 1.4e-17 63.9 0.1 2.2 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIE82545.1 - 0.0003 20.7 4.2 0.00057 19.8 0.0 2.8 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal RRM_1 PF00076.17 EIE82546.1 - 2.6e-55 183.9 1.3 5.4e-20 70.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE82546.1 - 2.5e-43 145.9 1.7 1.4e-14 53.8 0.1 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE82546.1 - 3.6e-30 103.5 0.5 2.1e-09 37.0 0.1 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EIE82546.1 - 0.0041 16.8 0.2 2.4 8.0 0.0 3.2 3 1 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Cas_Cas2CT1978 PF09707.5 EIE82546.1 - 0.032 14.1 0.2 3.1 7.8 0.0 2.7 3 0 0 3 3 3 0 CRISPR-associated protein (Cas_Cas2CT1978) OB_RNB PF08206.6 EIE82546.1 - 0.071 12.6 0.2 14 5.2 0.0 2.7 2 0 0 2 2 2 0 Ribonuclease B OB domain RRM_3 PF08777.6 EIE82546.1 - 0.14 12.0 0.2 13 5.6 0.0 3.1 3 0 0 3 3 3 0 RNA binding motif RNase_PH PF01138.16 EIE82547.1 - 3.6e-09 37.0 0.0 3.9e-09 36.9 0.0 1.0 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Kinesin PF00225.18 EIE82549.1 - 6.4e-71 238.7 4.2 5e-39 133.9 0.0 2.5 2 1 1 3 3 3 2 Kinesin motor domain CYSTM PF12734.2 EIE82550.1 - 2e-07 30.9 9.2 2e-07 30.9 6.4 3.1 2 1 0 2 2 2 1 Cysteine-rich TM module stress tolerance Pkinase PF00069.20 EIE82551.1 - 5.3e-60 202.7 0.0 6.7e-60 202.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE82551.1 - 8.1e-39 133.2 0.0 1.2e-38 132.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EIE82551.1 - 4e-06 26.2 0.4 1e-05 24.9 0.3 1.6 1 1 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 EIE82551.1 - 6.1e-05 22.1 0.0 0.00012 21.1 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 EIE82551.1 - 0.00071 19.3 0.1 0.0013 18.4 0.1 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EIE82551.1 - 0.1 12.1 0.4 0.24 10.9 0.2 1.6 1 1 0 1 1 1 0 Choline/ethanolamine kinase CUE PF02845.11 EIE82552.1 - 5e-05 22.6 0.2 0.15 11.5 0.0 3.8 3 0 0 3 3 3 3 CUE domain Kinesin PF00225.18 EIE82554.1 - 3.3e-90 302.1 0.9 3.3e-90 302.1 0.7 2.2 2 0 0 2 2 2 1 Kinesin motor domain SH3_1 PF00018.23 EIE82555.1 - 9.3e-15 53.7 0.1 1.7e-14 52.9 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EIE82555.1 - 5.9e-13 48.1 0.2 1.3e-12 47.1 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EIE82555.1 - 1.1e-11 43.9 0.0 1.7e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.21 EIE82555.1 - 0.01 15.7 0.3 0.01 15.7 0.2 1.9 2 0 0 2 2 2 0 WW domain RasGEF PF00617.14 EIE82556.1 - 8.9e-58 195.1 3.7 8.9e-58 195.1 2.6 2.0 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 EIE82556.1 - 1.2e-28 99.2 0.6 1.2e-28 99.2 0.4 2.5 2 0 0 2 2 2 1 RasGEF N-terminal motif WD40 PF00400.27 EIE82557.1 - 3e-17 61.7 1.3 1.6e-05 24.6 0.0 5.0 4 1 0 4 4 4 3 WD domain, G-beta repeat MMS1_N PF10433.4 EIE82557.1 - 0.003 15.7 0.0 0.024 12.8 0.0 2.0 1 1 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term eIF2A PF08662.6 EIE82557.1 - 0.042 13.5 0.1 0.23 11.1 0.0 2.3 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A ETS_PEA3_N PF04621.8 EIE82558.1 - 0.014 14.6 6.1 0.015 14.5 4.2 1.1 1 0 0 1 1 1 0 PEA3 subfamily ETS-domain transcription factor N terminal domain Pal1 PF08316.6 EIE82558.1 - 0.23 11.9 4.3 0.3 11.5 3.0 1.2 1 0 0 1 1 1 0 Pal1 cell morphology protein CPSF100_C PF13299.1 EIE82558.1 - 0.66 10.1 4.1 0.84 9.8 2.8 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Bax1-I PF01027.15 EIE82559.1 - 0.085 12.4 0.0 0.085 12.4 0.0 1.0 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 bZIP_2 PF07716.10 EIE82560.1 - 4.1e-06 26.5 10.0 4.1e-06 26.5 7.0 2.8 2 1 0 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.16 EIE82560.1 - 0.00025 20.9 18.2 0.0017 18.2 6.1 2.4 2 0 0 2 2 2 2 bZIP transcription factor ABC_tran_2 PF12848.2 EIE82560.1 - 0.083 12.7 0.3 0.083 12.7 0.2 2.3 2 0 0 2 2 2 0 ABC transporter TSC22 PF01166.13 EIE82560.1 - 0.27 11.2 3.8 0.78 9.7 0.5 2.7 1 1 0 2 2 2 0 TSC-22/dip/bun family DDRGK PF09756.4 EIE82560.1 - 4.3 6.7 12.2 10 5.4 8.4 1.5 1 1 0 1 1 1 0 DDRGK domain PUF PF00806.14 EIE82561.1 - 3e-24 83.0 0.1 2.2e-07 29.9 0.0 5.9 5 0 0 5 5 5 4 Pumilio-family RNA binding repeat RRM_1 PF00076.17 EIE82561.1 - 7.9e-13 47.8 0.0 2.4e-11 43.0 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE82561.1 - 1.9e-09 37.2 0.1 1.6e-07 31.0 0.0 2.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE82561.1 - 9.9e-08 31.8 0.0 4.5e-07 29.7 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DDE_3 PF13358.1 EIE82562.1 - 4.4e-19 68.6 0.2 2.4e-13 50.0 0.0 2.4 2 1 1 3 3 3 2 DDE superfamily endonuclease DUF4043 PF13252.1 EIE82562.1 - 0.0036 16.3 0.1 1 8.2 0.1 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF4043) HTH_32 PF13565.1 EIE82562.1 - 0.084 13.6 0.0 0.17 12.6 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain Yippee-Mis18 PF03226.9 EIE82563.1 - 5.1e-22 77.7 0.3 6.4e-22 77.4 0.2 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.3 EIE82563.1 - 0.13 12.0 0.4 0.23 11.3 0.3 1.4 1 1 0 1 1 1 0 C-terminal domain of RIG-I Evr1_Alr PF04777.8 EIE82563.1 - 0.14 12.0 0.2 0.2 11.5 0.1 1.5 1 1 0 1 1 1 0 Erv1 / Alr family EIIBC-GUT_N PF03612.9 EIE82567.1 - 0.023 14.3 0.0 0.03 13.9 0.0 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus HTH_Tnp_Tc3_2 PF01498.13 EIE82568.1 - 4.3e-09 36.2 0.5 5.3e-09 36.0 0.4 1.2 1 0 0 1 1 1 1 Transposase GRIN_C PF15235.1 EIE82568.1 - 0.35 10.9 2.4 0.49 10.4 1.7 1.4 1 1 0 1 1 1 0 G protein-regulated inducer of neurite outgrowth C-terminus DUF2414 PF10309.4 EIE82568.1 - 0.64 9.7 3.8 1.1 8.9 2.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2414) YchF-GTPase_C PF06071.8 EIE82570.1 - 1.1e-38 130.8 0.8 2.6e-38 129.6 0.3 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 EIE82570.1 - 1.1e-19 70.5 0.0 2e-19 69.6 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EIE82570.1 - 6.3e-08 32.0 0.0 1.2e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_17 PF13207.1 EIE82570.1 - 0.00085 20.1 0.0 0.0051 17.6 0.0 2.4 1 1 0 1 1 1 1 AAA domain MobB PF03205.9 EIE82570.1 - 0.006 16.2 0.0 1 9.0 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 EIE82570.1 - 0.0061 16.3 0.0 1.5 8.6 0.0 2.6 2 1 1 3 3 3 1 Dynamin family AAA_10 PF12846.2 EIE82570.1 - 0.0091 15.4 0.0 0.11 11.8 0.0 2.1 1 1 0 1 1 1 1 AAA-like domain ArgK PF03308.11 EIE82570.1 - 0.01 14.6 0.3 0.023 13.4 0.0 1.7 2 0 0 2 2 2 0 ArgK protein TGS PF02824.16 EIE82570.1 - 0.029 14.1 0.0 0.062 13.1 0.0 1.5 1 0 0 1 1 1 0 TGS domain EF-hand_1 PF00036.27 EIE82571.1 - 6.6e-25 84.4 8.2 7.3e-07 28.0 0.1 5.9 6 1 0 6 6 6 4 EF hand EF-hand_7 PF13499.1 EIE82571.1 - 1.8e-24 85.6 1.4 9.3e-10 38.5 0.0 3.3 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 EIE82571.1 - 7.3e-22 75.2 4.6 0.00011 21.8 0.0 4.9 5 0 0 5 5 5 4 EF-hand domain EF-hand_5 PF13202.1 EIE82571.1 - 2.5e-19 67.6 4.0 0.00082 18.6 0.0 4.6 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 EIE82571.1 - 5.6e-19 67.5 8.2 6.1e-11 41.7 0.0 4.5 3 2 2 5 5 5 5 EF-hand domain pair EF-hand_9 PF14658.1 EIE82571.1 - 0.0014 18.4 0.1 0.15 12.0 0.0 3.1 3 1 0 3 3 3 1 EF-hand domain Toprim_2 PF13155.1 EIE82571.1 - 0.036 14.4 0.4 2.3 8.5 0.0 2.8 2 1 2 4 4 4 0 Toprim-like EF-hand_4 PF12763.2 EIE82571.1 - 0.096 12.4 2.8 0.27 10.9 0.2 2.5 1 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand MOZ_SAS PF01853.13 EIE82572.1 - 6e-80 266.9 1.9 6e-80 266.9 1.3 1.7 2 0 0 2 2 2 1 MOZ/SAS family PHD PF00628.24 EIE82572.1 - 2.5e-12 46.2 22.0 2.8e-10 39.7 7.2 3.4 2 1 1 3 3 3 2 PHD-finger He_PIG_assoc PF10632.4 EIE82572.1 - 0.096 12.0 0.1 0.24 10.7 0.1 1.6 1 0 0 1 1 1 0 He_PIG associated, NEW1 domain of bacterial glycohydrolase LexA_DNA_bind PF01726.11 EIE82572.1 - 0.13 11.8 0.0 0.33 10.5 0.0 1.7 1 0 0 1 1 1 0 LexA DNA binding domain MatE PF01554.13 EIE82573.1 - 5.4e-46 156.1 27.6 2.5e-26 92.2 6.8 2.2 2 0 0 2 2 2 2 MatE PRK PF00485.13 EIE82575.1 - 3.2e-48 163.8 0.0 4e-48 163.5 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.1 EIE82575.1 - 3.5e-26 91.6 0.0 2.6e-14 52.9 0.0 2.3 1 1 1 2 2 2 2 Uracil phosphoribosyltransferase AAA_18 PF13238.1 EIE82575.1 - 1.2e-05 25.5 0.0 2.1e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EIE82575.1 - 0.00013 21.8 0.0 0.00028 20.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain CPT PF07931.7 EIE82575.1 - 0.00018 21.1 0.0 0.00034 20.2 0.0 1.6 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_17 PF13207.1 EIE82575.1 - 0.00025 21.8 0.0 0.00062 20.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain CoaE PF01121.15 EIE82575.1 - 0.056 12.8 0.0 2.8 7.2 0.0 2.2 2 0 0 2 2 2 0 Dephospho-CoA kinase IFT46_B_C PF12317.3 EIE82575.1 - 0.086 12.1 0.1 0.25 10.6 0.1 1.7 1 1 1 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal SH3BGR PF04908.10 EIE82576.1 - 6.6e-15 54.8 0.2 6.6e-15 54.8 0.2 3.5 3 0 0 3 3 3 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.19 EIE82576.1 - 4.8e-07 29.6 0.2 4.4e-06 26.5 0.0 2.7 2 0 0 2 2 2 1 Glutaredoxin DUF3450 PF11932.3 EIE82576.1 - 0.0028 16.9 21.0 0.0028 16.9 14.6 4.1 1 1 4 5 5 5 1 Protein of unknown function (DUF3450) AAA_23 PF13476.1 EIE82576.1 - 0.0035 17.6 8.8 0.0035 17.6 6.1 4.8 3 1 0 3 3 3 1 AAA domain DUF1574 PF07611.6 EIE82576.1 - 0.01 14.7 0.0 0.01 14.7 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1574) HtrL_YibB PF09612.5 EIE82576.1 - 0.06 12.6 0.3 0.15 11.3 0.2 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (HtrL_YibB) Kinase-like PF14531.1 EIE82577.1 - 0.13 11.1 0.0 0.15 11.0 0.0 1.0 1 0 0 1 1 1 0 Kinase-like Daxx PF03344.10 EIE82578.1 - 0.034 12.6 8.9 0.038 12.4 6.2 1.1 1 0 0 1 1 1 0 Daxx Family Myc_N PF01056.13 EIE82578.1 - 0.12 11.5 7.9 1.5 7.9 2.9 2.2 2 0 0 2 2 2 0 Myc amino-terminal region Spt5_N PF11942.3 EIE82578.1 - 1.2 9.7 14.3 1.2 9.7 0.5 2.5 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal DUF3682 PF12446.3 EIE82578.1 - 3 8.1 15.3 7.5 6.8 2.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3682) Nucleoplasmin PF03066.10 EIE82578.1 - 6.2 6.3 10.7 1.1 8.7 1.5 2.4 2 0 0 2 2 2 0 Nucleoplasmin DUF3347 PF11827.3 EIE82578.1 - 8.1 6.4 8.7 12 5.8 6.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3347) DnaJ-X PF14308.1 EIE82580.1 - 9.2e-29 100.1 4.3 8e-28 97.1 2.9 2.2 2 1 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.26 EIE82580.1 - 3.8e-18 64.9 4.0 2.1e-17 62.6 0.5 2.7 2 0 0 2 2 2 1 DnaJ domain DUF3682 PF12446.3 EIE82580.1 - 0.039 14.2 1.2 0.1 12.8 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) PRAP PF15314.1 EIE82580.1 - 0.54 10.5 0.1 0.54 10.5 0.0 2.5 3 1 0 3 3 3 0 Proline-rich acidic protein 1, pregnancy-specific uterine DUF3450 PF11932.3 EIE82580.1 - 0.6 9.3 6.9 12 5.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) TipAS PF07739.8 EIE82580.1 - 1.8 8.8 8.3 11 6.3 0.1 2.9 2 1 0 2 2 2 0 TipAS antibiotic-recognition domain Phage_int_SAM_5 PF13102.1 EIE82580.1 - 3.2 7.7 9.8 0.48 10.4 1.4 2.5 3 0 0 3 3 3 0 Phage integrase SAM-like domain E1_dh PF00676.15 EIE82582.1 - 2.5e-46 157.7 0.0 5.4e-46 156.6 0.0 1.6 2 0 0 2 2 2 1 Dehydrogenase E1 component Transket_pyr PF02779.19 EIE82582.1 - 3.9e-46 156.7 0.0 5.5e-46 156.2 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain FAD_binding_2 PF00890.19 EIE82583.1 - 3.7e-125 418.0 4.8 5.1e-125 417.5 3.3 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 EIE82583.1 - 3e-48 162.9 0.5 4.4e-48 162.3 0.3 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 EIE82583.1 - 1.3e-07 31.7 0.0 2.6e-05 24.2 0.0 2.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EIE82583.1 - 5.7e-06 25.5 0.2 0.0076 15.3 0.0 2.4 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.17 EIE82583.1 - 1.7e-05 23.8 1.8 0.011 14.6 1.6 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A DAO PF01266.19 EIE82583.1 - 6.7e-05 21.9 0.1 0.00071 18.5 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EIE82583.1 - 0.0042 16.1 0.2 0.0074 15.3 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EIE82583.1 - 0.03 12.8 2.0 0.42 9.0 0.6 3.0 4 0 0 4 4 4 0 HI0933-like protein Pyr_redox_3 PF13738.1 EIE82583.1 - 0.25 11.4 4.0 2.6 8.0 1.5 3.1 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase ubiquitin PF00240.18 EIE82584.1 - 1.3e-26 91.8 0.0 1.4e-26 91.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EIE82584.1 - 5.3e-17 61.2 0.0 5.8e-17 61.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EIE82584.1 - 4.2e-05 23.7 0.0 0.00011 22.4 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-like domain CTDII PF01556.13 EIE82584.1 - 0.14 12.0 0.5 0.18 11.7 0.3 1.3 1 1 0 1 1 1 0 DnaJ C terminal domain Cu-oxidase PF00394.17 EIE82585.1 - 5.4e-35 120.6 0.1 4.3e-34 117.7 0.0 2.2 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 EIE82585.1 - 1e-31 109.1 0.1 3.4e-31 107.4 0.1 2.0 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EIE82585.1 - 1.1e-18 67.0 7.4 2.7e-15 56.0 2.2 4.1 2 2 0 2 2 2 2 Multicopper oxidase DUF3425 PF11905.3 EIE82586.1 - 4e-15 55.9 9.7 2.8e-13 49.9 5.7 3.0 2 1 0 2 2 2 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 EIE82586.1 - 6.3e-10 38.8 5.5 1.3e-09 37.8 3.8 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EIE82586.1 - 0.0034 17.1 12.5 0.01 15.6 8.7 1.7 1 0 0 1 1 1 1 Basic region leucine zipper UPF0242 PF06785.6 EIE82586.1 - 0.57 8.7 5.9 0.33 9.5 1.8 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) HLH PF00010.21 EIE82587.1 - 1.4e-13 50.2 0.5 5.9e-13 48.3 0.1 2.2 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain CBP4 PF07960.6 EIE82587.1 - 0.014 15.0 1.5 0.024 14.2 1.1 1.4 1 0 0 1 1 1 0 CBP4 DUF3800 PF12686.2 EIE82587.1 - 0.02 14.5 1.9 0.1 12.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3800) PPV_E1_N PF00524.13 EIE82587.1 - 0.1 12.8 3.5 7.1 6.8 0.2 2.4 2 1 0 2 2 2 0 E1 Protein, N terminal domain SlyX PF04102.7 EIE82587.1 - 0.28 11.5 2.5 2.5 8.5 0.1 2.7 2 0 0 2 2 2 0 SlyX SR-25 PF10500.4 EIE82587.1 - 0.34 10.3 10.4 0.3 10.5 5.4 2.0 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein Transposase_21 PF02992.9 EIE82589.1 - 2.3e-23 82.4 0.1 2.3e-23 82.4 0.0 1.6 2 0 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.1 EIE82589.1 - 1.3e-05 24.6 0.3 2.5e-05 23.7 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) DDE_3 PF13358.1 EIE82590.1 - 2.6e-19 69.4 0.3 1.8e-18 66.6 0.0 2.4 3 0 0 3 3 3 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE82590.1 - 8.5e-12 44.9 0.9 1.9e-11 43.8 0.7 1.7 1 0 0 1 1 1 1 Transposase AftA_C PF12249.3 EIE82591.1 - 0.08 12.3 0.1 0.083 12.3 0.1 1.1 1 0 0 1 1 1 0 Arabinofuranosyltransferase A C terminal zf-CCHC PF00098.18 EIE82592.1 - 0.0078 16.1 4.7 0.0078 16.1 3.2 3.6 3 0 0 3 3 3 2 Zinc knuckle zf-CCHC_6 PF15288.1 EIE82592.1 - 0.0081 15.8 1.6 0.0081 15.8 1.1 1.9 2 0 0 2 2 2 1 Zinc knuckle DDE_3 PF13358.1 EIE82593.1 - 7.1e-18 64.7 0.4 1e-17 64.2 0.3 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE82594.1 - 6.9e-06 26.0 0.8 2e-05 24.5 0.1 2.0 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.1 EIE82594.1 - 6.7e-05 22.6 0.0 0.00011 21.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Exo_endo_phos PF03372.18 EIE82595.1 - 6.9e-06 26.1 0.1 9.9e-06 25.6 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EIE82595.1 - 1.2e-05 24.8 0.0 2.3e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase DDE_3 PF13358.1 EIE82596.1 - 3.6e-12 46.2 0.2 4.7e-12 45.8 0.2 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EIE82597.1 - 8e-13 48.3 0.0 1.3e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF2567 PF10821.3 EIE82597.1 - 0.15 11.6 0.0 0.2 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2567) DDE_3 PF13358.1 EIE82598.1 - 5.4e-21 74.8 0.0 1.1e-20 73.8 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE82598.1 - 1.1e-15 57.4 1.9 2.8e-15 56.1 0.3 2.3 3 0 0 3 3 2 1 Transposase HTH_29 PF13551.1 EIE82598.1 - 2.7e-06 27.5 0.2 8.6e-06 25.8 0.2 1.9 2 0 0 2 2 1 1 Winged helix-turn helix HTH_38 PF13936.1 EIE82598.1 - 1.2e-05 24.7 0.1 3.3e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.1 EIE82598.1 - 7.6e-05 22.2 0.1 0.0028 17.2 0.0 2.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.1 EIE82598.1 - 8.8e-05 23.2 2.8 0.02 15.6 0.1 3.7 4 0 0 4 4 3 1 Homeodomain-like domain Sigma70_r4_2 PF08281.7 EIE82598.1 - 0.00054 19.3 0.6 0.024 14.0 0.0 3.2 4 0 0 4 4 4 1 Sigma-70, region 4 HTH_28 PF13518.1 EIE82598.1 - 0.0013 18.7 0.0 0.0056 16.6 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_21 PF13276.1 EIE82598.1 - 0.0014 18.5 0.1 0.13 12.2 0.0 2.8 3 0 0 3 3 3 1 HTH-like domain HTH_7 PF02796.10 EIE82598.1 - 0.0022 17.7 1.1 0.1 12.4 0.0 2.8 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase rve PF00665.21 EIE82598.1 - 0.0045 17.0 0.0 0.014 15.4 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain LacI PF00356.16 EIE82598.1 - 0.018 14.6 1.7 2.8 7.6 0.2 2.7 3 0 0 3 3 3 0 Bacterial regulatory proteins, lacI family HTH_Tnp_4 PF13613.1 EIE82598.1 - 0.022 14.2 0.1 0.057 12.9 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease CPSase_L_D3 PF02787.14 EIE82598.1 - 0.058 13.1 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain HTH_36 PF13730.1 EIE82598.1 - 0.074 13.1 0.4 4.1 7.6 0.0 2.9 3 0 0 3 3 2 0 Helix-turn-helix domain Sigma70_r4 PF04545.11 EIE82598.1 - 0.1 11.9 0.2 0.79 9.0 0.0 2.6 4 0 0 4 4 4 0 Sigma-70, region 4 HTH_Tnp_ISL3 PF13542.1 EIE82598.1 - 0.15 11.2 2.5 8.4 5.6 0.0 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 HTH_17 PF12728.2 EIE82598.1 - 0.2 11.9 2.4 15 5.9 0.1 3.2 3 0 0 3 3 3 0 Helix-turn-helix domain rve PF00665.21 EIE82600.1 - 1.9e-22 79.6 0.0 4.5e-22 78.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE82600.1 - 1.4e-15 57.2 0.1 2.8e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.12 EIE82600.1 - 8.2e-09 35.4 0.1 2.3e-08 34.0 0.1 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein Chromo PF00385.19 EIE82600.1 - 4.2e-08 32.7 0.1 9.7e-08 31.5 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 EIE82600.1 - 0.00047 19.5 1.6 0.0015 17.9 1.1 1.9 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger UBN2 PF14223.1 EIE82600.1 - 0.13 12.0 0.0 0.36 10.6 0.0 1.8 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Med15 PF09606.5 EIE82601.1 - 0.028 12.6 12.5 0.04 12.1 8.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal FlgM PF04316.8 EIE82601.1 - 2.2 8.2 5.1 13 5.8 2.9 2.3 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM Transposase_21 PF02992.9 EIE82602.1 - 6.8e-22 77.6 0.0 1.5e-21 76.5 0.0 1.5 1 0 0 1 1 1 1 Transposase family tnp2 DUF1258 PF06869.7 EIE82602.1 - 0.0025 16.9 0.0 0.0041 16.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) HTH_Tnp_Tc3_2 PF01498.13 EIE82604.1 - 2.1e-08 34.1 2.9 4.6e-08 33.0 0.4 2.1 1 1 1 2 2 2 1 Transposase Cas_Csd1 PF09709.5 EIE82605.1 - 0.034 12.4 0.2 0.041 12.1 0.1 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csd1) rve PF00665.21 EIE82606.1 - 1.1e-24 86.8 0.0 3.5e-24 85.1 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE82606.1 - 6.2e-17 61.6 0.0 1.3e-16 60.5 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE82606.1 - 7.3e-11 41.5 0.6 2.6e-10 39.8 0.4 2.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 EIE82606.1 - 0.00037 19.8 0.1 0.001 18.3 0.1 1.8 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger UBN2_2 PF14227.1 EIE82606.1 - 0.0094 15.4 0.4 0.29 10.7 0.0 2.8 3 0 0 3 3 3 1 gag-polypeptide of LTR copia-type rve_3 PF13683.1 EIE82606.1 - 0.031 13.8 0.0 0.087 12.3 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain UBN2 PF14223.1 EIE82606.1 - 0.07 12.9 0.2 0.26 11.1 0.0 2.0 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type RVT_1 PF00078.22 EIE82608.1 - 4.8e-24 84.9 0.8 1.1e-23 83.7 0.5 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP PF00077.15 EIE82608.1 - 1e-06 28.5 0.0 2.2e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EIE82608.1 - 7.5e-06 25.6 0.0 1.8e-05 24.4 0.0 1.7 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EIE82608.1 - 1.6e-05 25.3 0.0 3.1e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.18 EIE82608.1 - 0.0028 17.5 1.3 0.0028 17.5 0.9 2.3 2 0 0 2 2 2 1 Zinc knuckle RVP_2 PF08284.6 EIE82608.1 - 0.0041 17.0 0.0 0.0088 15.9 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 EIE82608.1 - 0.053 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC_2 PF13696.1 EIE82608.1 - 0.54 9.8 4.7 0.16 11.5 0.4 2.2 2 0 0 2 2 2 0 Zinc knuckle Retrotrans_gag PF03732.12 EIE82611.1 - 1.1e-18 67.1 2.3 1.6e-18 66.5 0.4 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.18 EIE82611.1 - 0.046 13.6 1.0 0.071 13.0 0.7 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.1 EIE82611.1 - 0.15 11.5 0.6 0.3 10.6 0.4 1.4 1 0 0 1 1 1 0 Zinc knuckle Leader_Erm PF08253.6 EIE82612.1 - 0.33 10.4 0.3 0.33 10.4 0.2 2.1 2 0 0 2 2 2 0 Erm Leader peptide GCR1_C PF12550.3 EIE82613.1 - 5.1e-26 90.3 0.7 5.1e-25 87.1 0.2 2.6 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes Zwint PF15556.1 EIE82614.1 - 0.067 12.4 0.1 0.091 12.0 0.0 1.1 1 0 0 1 1 1 0 ZW10 interactor HAD PF12710.2 EIE82617.1 - 3.9e-11 43.4 0.1 5.2e-11 43.0 0.1 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EIE82617.1 - 5.2e-05 23.5 0.5 0.00018 21.7 0.3 1.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase UMPH-1 PF05822.7 EIE82617.1 - 0.00063 19.1 0.1 0.0044 16.3 0.0 1.9 1 1 0 2 2 2 1 Pyrimidine 5'-nucleotidase (UMPH-1) Hydrolase PF00702.21 EIE82617.1 - 0.06 13.7 0.1 0.21 11.9 0.0 1.9 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase CGI-121 PF08617.5 EIE82618.1 - 1.4e-36 125.6 5.5 1.5e-36 125.4 3.8 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 GHL13 PF14883.1 EIE82618.1 - 0.0057 15.8 0.1 0.0058 15.8 0.1 1.2 1 0 0 1 1 1 1 Hypothetical glycosyl hydrolase family 13 FAM131 PF15010.1 EIE82618.1 - 0.1 12.3 0.0 0.12 12.1 0.0 1.0 1 0 0 1 1 1 0 Putative cell signalling PRP21_like_P PF12230.3 EIE82619.1 - 1.1e-65 221.4 8.0 1.1e-65 221.4 5.5 1.6 2 0 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 EIE82619.1 - 4.4e-18 64.6 0.7 7.6e-18 63.9 0.1 1.7 2 0 0 2 2 2 1 Surp module ubiquitin PF00240.18 EIE82619.1 - 3.8e-07 29.3 0.0 6e-06 25.5 0.0 2.4 2 0 0 2 2 2 1 Ubiquitin family Ubiquitin_2 PF14560.1 EIE82619.1 - 0.033 14.4 0.2 0.17 12.1 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain UPF0547 PF10571.4 EIE82619.1 - 0.16 11.7 0.2 0.25 11.0 0.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 SMN PF06003.7 EIE82619.1 - 1.4 7.9 10.0 0.14 11.2 3.6 1.8 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) Med2 PF11214.3 EIE82619.1 - 1.9 8.5 6.9 0.78 9.8 0.8 2.5 2 0 0 2 2 2 0 Mediator complex subunit 2 BPL_N PF09825.4 EIE82620.1 - 3.2e-54 184.1 0.0 4.4e-54 183.6 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.14 EIE82620.1 - 1.5e-11 44.3 0.0 4.7e-11 42.7 0.0 1.8 2 0 0 2 2 2 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.12 EIE82620.1 - 6.5e-06 25.7 0.0 1.3e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain Heme_oxygenase PF01126.15 EIE82621.1 - 3.8e-56 189.9 1.5 5.1e-56 189.5 1.0 1.2 1 0 0 1 1 1 1 Heme oxygenase DUF4407 PF14362.1 EIE82622.1 - 0.2 10.5 0.1 0.2 10.5 0.1 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) AATF-Che1 PF13339.1 EIE82623.1 - 2.6e-29 102.0 0.5 2.6e-29 102.0 0.3 3.5 3 2 0 3 3 3 1 Apoptosis antagonizing transcription factor TRAUB PF08164.7 EIE82623.1 - 2.4e-11 43.5 1.9 2.4e-11 43.5 1.3 2.5 2 0 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal EXS PF03124.9 EIE82624.1 - 0.016 14.2 0.2 0.023 13.7 0.2 1.3 1 0 0 1 1 1 0 EXS family SPX PF03105.14 EIE82625.1 - 2e-40 139.3 10.9 3.6e-20 72.8 0.7 2.2 1 1 1 2 2 2 2 SPX domain EXS PF03124.9 EIE82625.1 - 2.5e-19 69.5 6.0 3.8e-19 68.9 4.1 1.1 1 0 0 1 1 1 1 EXS family CrtC PF07143.6 EIE82625.1 - 0.018 14.3 0.1 0.029 13.6 0.0 1.2 1 0 0 1 1 1 0 Hydroxyneurosporene synthase (CrtC) Pox_A14 PF05767.7 EIE82625.1 - 0.25 11.2 1.5 0.63 10.0 0.3 2.1 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 SH PF01445.12 EIE82625.1 - 0.27 10.9 4.4 0.12 11.9 0.3 2.4 2 1 0 2 2 2 0 Viral small hydrophobic protein RNB PF00773.14 EIE82626.1 - 0.015 14.6 0.1 0.026 13.8 0.0 1.3 1 0 0 1 1 1 0 RNB domain RNB PF00773.14 EIE82627.1 - 3.7e-23 82.3 3.9 1.4e-16 60.6 0.0 2.6 3 0 0 3 3 3 2 RNB domain TMV_coat PF00721.16 EIE82629.1 - 0.063 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Virus coat protein (TMV like) DUF1729 PF08354.5 EIE82630.1 - 0.045 13.5 0.4 0.058 13.2 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1729) HLH PF00010.21 EIE82631.1 - 6.4e-17 60.9 4.4 1.4e-16 59.9 3.1 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF1640 PF07798.6 EIE82632.1 - 2.4e-48 164.5 6.7 2.6e-48 164.3 4.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) TPR_MLP1_2 PF07926.7 EIE82632.1 - 0.024 14.3 7.6 0.028 14.1 1.1 2.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein HALZ PF02183.13 EIE82632.1 - 0.048 13.3 1.8 0.33 10.6 0.3 2.8 3 1 0 3 3 3 0 Homeobox associated leucine zipper DUF342 PF03961.8 EIE82632.1 - 0.051 11.9 2.9 0.059 11.7 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF4407 PF14362.1 EIE82632.1 - 0.099 11.5 2.0 0.1 11.5 1.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF972 PF06156.8 EIE82632.1 - 0.23 11.8 5.3 1.6 9.1 2.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) FlaC_arch PF05377.6 EIE82632.1 - 0.26 11.2 4.9 11 5.9 0.7 2.8 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF4200 PF13863.1 EIE82632.1 - 0.29 11.1 9.9 0.43 10.5 6.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) DUF3166 PF11365.3 EIE82632.1 - 0.32 11.4 3.3 0.77 10.2 2.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3166) TBPIP PF07106.8 EIE82632.1 - 0.52 9.8 6.5 0.87 9.1 4.5 1.4 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Phage_GP20 PF06810.6 EIE82632.1 - 0.57 9.6 5.0 1 8.8 3.4 1.4 1 1 0 1 1 1 0 Phage minor structural protein GP20 DivIC PF04977.10 EIE82632.1 - 0.63 9.5 6.9 0.79 9.2 1.9 2.3 1 1 1 2 2 2 0 Septum formation initiator GreA_GreB_N PF03449.10 EIE82632.1 - 0.78 9.8 5.9 2.3 8.3 3.5 2.1 1 1 0 1 1 1 0 Transcription elongation factor, N-terminal DUF883 PF05957.8 EIE82632.1 - 1.8 8.9 4.7 5.6 7.4 3.2 2.0 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) bZIP_2 PF07716.10 EIE82632.1 - 3.5 7.5 7.3 17 5.3 2.2 3.0 2 1 1 3 3 3 0 Basic region leucine zipper zf-CCCH PF00642.19 EIE82633.1 - 4.8e-06 26.1 2.5 4.8e-06 26.1 1.8 1.7 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-U1 PF06220.7 EIE82633.1 - 1.5e-05 24.4 9.3 1.5e-05 24.4 6.4 2.5 2 1 0 2 2 2 1 U1 zinc finger Opi1 PF08618.5 EIE82634.1 - 2.4e-50 171.7 10.7 1.7e-36 126.1 3.5 3.2 1 1 2 3 3 3 3 Transcription factor Opi1 Perilipin PF03036.11 EIE82634.1 - 4.9e-05 22.3 0.4 0.00031 19.7 0.0 2.4 2 1 0 2 2 2 1 Perilipin family Golgin_A5 PF09787.4 EIE82634.1 - 0.035 12.6 3.7 0.057 11.9 2.5 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 REF PF05755.7 EIE82634.1 - 0.079 12.7 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Rubber elongation factor protein (REF) Exo_endo_phos PF03372.18 EIE82635.1 - 2.4e-13 50.5 0.4 3.8e-13 49.9 0.3 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RGS PF00615.14 EIE82636.1 - 5.1e-12 45.9 0.3 5.5e-11 42.5 0.2 2.3 1 1 0 1 1 1 1 Regulator of G protein signaling domain Pol_alpha_B_N PF08418.5 EIE82636.1 - 0.053 13.0 0.2 0.093 12.2 0.1 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Neurensin PF14927.1 EIE82636.1 - 0.13 11.6 0.2 0.24 10.7 0.1 1.3 1 0 0 1 1 1 0 Neurensin F-box-like PF12937.2 EIE82637.1 - 0.0011 18.7 0.5 0.0025 17.5 0.0 1.9 2 0 0 2 2 2 1 F-box-like PRANC PF09372.5 EIE82637.1 - 0.1 12.5 0.5 0.21 11.5 0.1 1.7 2 0 0 2 2 2 0 PRANC domain Ecl1 PF12855.2 EIE82638.1 - 9.4e-08 31.2 10.8 1.3e-07 30.7 7.5 1.3 1 0 0 1 1 1 1 Life-span regulatory factor DUF3079 PF11278.3 EIE82638.1 - 0.17 11.4 5.8 0.28 10.7 4.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3079) ICAM_N PF03921.9 EIE82638.1 - 0.76 9.2 4.0 1.9 7.9 2.8 1.7 1 1 0 1 1 1 0 Intercellular adhesion molecule (ICAM), N-terminal domain DUF2116 PF09889.4 EIE82638.1 - 1.4 8.7 6.0 1.9 8.3 4.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) ADH_zinc_N PF00107.21 EIE82640.1 - 5.8e-25 87.3 0.0 1e-24 86.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIE82640.1 - 4.5e-06 27.5 0.0 8e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase bPH_3 PF14470.1 EIE82641.1 - 0.048 13.9 0.1 0.049 13.8 0.1 1.1 1 0 0 1 1 1 0 Bacterial PH domain WD40 PF00400.27 EIE82642.1 - 5e-22 76.9 2.6 2.8e-06 27.0 0.0 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat PD40 PF07676.7 EIE82642.1 - 0.03 14.0 0.3 0.15 11.7 0.0 2.2 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat DNA_ligase_A_M PF01068.16 EIE82643.1 - 1e-57 194.7 0.9 1e-57 194.7 0.6 2.2 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EIE82643.1 - 6.2e-46 156.4 3.4 1.5e-43 148.6 2.3 2.6 1 1 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EIE82643.1 - 1.7e-26 92.4 0.0 7.9e-26 90.3 0.0 2.2 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region DNA_ligase_OB_2 PF14743.1 EIE82643.1 - 0.0098 15.5 0.1 3.5 7.3 0.0 2.5 2 0 0 2 2 2 2 DNA ligase OB-like domain EF_assoc_2 PF08356.7 EIE82644.1 - 3.6e-32 109.9 0.0 7.6e-32 108.9 0.0 1.6 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.7 EIE82644.1 - 1.2e-31 107.7 1.8 2.2e-31 106.9 1.2 1.4 1 0 0 1 1 1 1 EF hand associated Miro PF08477.8 EIE82644.1 - 7.1e-27 94.2 0.0 1.3e-14 54.6 0.0 2.4 2 0 0 2 2 2 2 Miro-like protein Ras PF00071.17 EIE82644.1 - 2.2e-13 49.9 0.0 2e-07 30.5 0.0 2.3 2 0 0 2 2 2 2 Ras family EF-hand_1 PF00036.27 EIE82644.1 - 1.5e-07 30.1 4.0 0.0032 16.6 0.3 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 EIE82644.1 - 1.8e-07 30.4 2.0 0.0013 18.4 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 EIE82644.1 - 1.6e-06 28.1 1.3 0.073 13.2 0.0 2.9 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 EIE82644.1 - 1.8e-05 23.8 7.9 0.0011 18.1 0.8 2.6 2 0 0 2 2 2 2 EF hand MMR_HSR1 PF01926.18 EIE82644.1 - 6.1e-05 22.9 0.0 0.0011 18.9 0.0 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EIE82644.1 - 0.00035 20.7 0.0 0.014 15.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain EF-hand_8 PF13833.1 EIE82644.1 - 0.00036 20.0 1.0 0.64 9.6 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_10 PF14788.1 EIE82644.1 - 0.00065 19.3 2.8 0.0094 15.5 0.2 2.4 2 0 0 2 2 2 1 EF hand Dynamin_N PF00350.18 EIE82644.1 - 0.0054 16.5 0.0 0.019 14.8 0.0 1.9 2 0 0 2 2 2 1 Dynamin family AAA PF00004.24 EIE82644.1 - 0.0057 16.8 0.0 0.011 15.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EIE82644.1 - 0.0074 16.2 0.0 0.018 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.1 EIE82644.1 - 0.032 13.8 0.0 0.058 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 EIE82644.1 - 0.035 13.6 0.0 0.057 12.9 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase SPARC_Ca_bdg PF10591.4 EIE82644.1 - 0.068 13.1 0.1 1.6 8.8 0.0 2.5 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Arch_ATPase PF01637.13 EIE82644.1 - 0.069 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_17 PF13207.1 EIE82644.1 - 0.075 13.8 0.0 0.23 12.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EIE82644.1 - 0.077 12.9 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EIE82644.1 - 0.098 12.3 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain UQ_con PF00179.21 EIE82645.1 - 3.2e-37 127.0 0.1 4.2e-37 126.6 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme NST1 PF13945.1 EIE82646.1 - 5.9e-46 156.9 9.6 5.9e-46 156.9 6.6 4.2 2 1 2 4 4 4 1 Salt tolerance down-regulator ABC1 PF03109.11 EIE82647.1 - 7.8e-32 109.7 0.1 1.1e-31 109.2 0.0 1.3 1 0 0 1 1 1 1 ABC1 family IKI3 PF04762.7 EIE82648.1 - 3e-274 912.3 0.0 4e-274 911.8 0.0 1.2 1 0 0 1 1 1 1 IKI3 family RNA_pol_Rpb1_1 PF04997.7 EIE82649.1 - 8.5e-114 380.3 0.0 1.1e-113 379.9 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 EIE82649.1 - 1.5e-71 239.6 0.0 2.2e-71 239.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EIE82649.1 - 6.1e-43 146.2 0.0 1.3e-42 145.2 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_R PF05001.8 EIE82650.1 - 1e-25 87.5 345.1 0.056 13.5 10.5 17.8 5 2 19 26 26 26 24 RNA polymerase Rpb1 C-terminal repeat Peptidase_C14 PF00656.17 EIE82651.1 - 1.1e-43 149.7 0.4 1.8e-43 149.0 0.3 1.2 1 0 0 1 1 1 1 Caspase domain UCR_hinge PF02320.11 EIE82652.1 - 3.5e-20 71.6 6.2 5.9e-20 70.9 4.3 1.4 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein Sigma70_ner PF04546.8 EIE82652.1 - 0.0016 18.1 3.2 0.0018 17.9 2.2 1.0 1 0 0 1 1 1 1 Sigma-70, non-essential region DUF3391 PF11871.3 EIE82652.1 - 0.023 14.9 1.1 0.028 14.6 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) Vicilin_N PF04702.7 EIE82652.1 - 0.075 12.6 8.3 0.097 12.2 5.8 1.1 1 0 0 1 1 1 0 Vicilin N terminal region zf-TAZ PF02135.11 EIE82652.1 - 0.11 12.5 3.0 0.13 12.2 2.1 1.2 1 0 0 1 1 1 0 TAZ zinc finger DUF3484 PF11983.3 EIE82652.1 - 0.25 12.1 3.8 0.4 11.5 2.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3484) DUF2052 PF09747.4 EIE82652.1 - 0.78 9.6 7.1 0.95 9.3 4.9 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Adeno_terminal PF02459.10 EIE82652.1 - 0.99 7.4 8.5 1.1 7.3 5.9 1.0 1 0 0 1 1 1 0 Adenoviral DNA terminal protein FYRN PF05964.9 EIE82654.1 - 1.1e-20 72.8 0.2 2.7e-20 71.5 0.2 1.7 1 0 0 1 1 1 1 F/Y-rich N-terminus FYRC PF05965.9 EIE82654.1 - 1e-15 57.2 0.0 2.5e-15 56.0 0.0 1.7 1 0 0 1 1 1 1 F/Y rich C-terminus DcpS_C PF11969.3 EIE82656.1 - 2.9e-28 98.4 0.0 1.2e-27 96.3 0.0 1.9 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.7 EIE82656.1 - 3.1e-23 82.2 0.2 6.2e-23 81.3 0.1 1.5 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal Pkinase PF00069.20 EIE82657.1 - 1.2e-74 250.7 0.0 2.1e-74 249.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE82657.1 - 1.7e-39 135.4 0.0 2.7e-39 134.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIE82657.1 - 3.2e-06 27.0 0.1 0.0011 18.7 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 EIE82657.1 - 0.041 13.4 1.3 0.048 13.2 0.1 1.7 2 0 0 2 2 2 0 Choline/ethanolamine kinase Kdo PF06293.9 EIE82657.1 - 0.095 11.7 0.1 0.16 10.9 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family WHIM2 PF15613.1 EIE82658.1 - 0.06 13.3 0.1 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 2 Phage_GP20 PF06810.6 EIE82658.1 - 0.87 9.0 9.7 0.25 10.7 4.6 1.7 2 0 0 2 2 2 0 Phage minor structural protein GP20 AnfG_VnfG PF03139.10 EIE82658.1 - 3.7 7.3 7.9 1.3 8.8 0.4 3.0 3 0 0 3 3 3 0 Vanadium/alternative nitrogenase delta subunit SH3_9 PF14604.1 EIE82659.1 - 5.3e-34 115.5 0.3 8.1e-19 66.9 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 EIE82659.1 - 2e-29 100.6 0.2 2.4e-17 62.0 0.1 2.5 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 EIE82659.1 - 2e-24 84.7 0.1 9.9e-16 56.9 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain FCH PF00611.18 EIE82659.1 - 2.8e-18 65.8 0.5 2.8e-18 65.8 0.3 1.9 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain C1_1 PF00130.17 EIE82659.1 - 2.4e-12 46.3 7.8 4.3e-12 45.5 5.4 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Antitoxin-MazE PF04014.13 EIE82659.1 - 0.012 15.3 0.6 2.5 7.9 0.0 2.5 2 0 0 2 2 2 0 Antidote-toxin recognition MazE Peptidase_S46 PF10459.4 EIE82659.1 - 4.9 5.4 11.6 1.4 7.1 1.3 2.1 1 1 1 2 2 2 0 Peptidase S46 MOSC_N PF03476.11 EIE82661.1 - 8.6e-27 93.2 0.0 1.4e-26 92.5 0.0 1.3 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 EIE82661.1 - 8.8e-18 64.0 0.0 1.8e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 MOSC domain FA_hydroxylase PF04116.8 EIE82662.1 - 6.3e-11 42.6 23.3 6.3e-11 42.6 16.1 2.4 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF4172 PF13776.1 EIE82662.1 - 0.038 14.0 0.0 0.068 13.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4172) DUF3796 PF12676.2 EIE82662.1 - 0.071 13.3 10.1 0.52 10.5 1.4 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3796) Ubie_methyltran PF01209.13 EIE82663.1 - 2.5e-83 278.7 0.1 3e-83 278.4 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EIE82663.1 - 5.2e-15 55.3 0.0 1e-14 54.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIE82663.1 - 9e-14 51.7 0.0 1.7e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIE82663.1 - 6.6e-11 42.1 0.0 1e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIE82663.1 - 2.8e-10 40.5 0.2 1.5e-09 38.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIE82663.1 - 3.9e-09 36.7 0.1 9.5e-09 35.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIE82663.1 - 1.2e-07 32.2 0.0 2.4e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIE82663.1 - 8e-05 22.6 0.0 0.00022 21.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EIE82663.1 - 0.0027 17.3 0.0 0.0073 15.9 0.0 1.7 2 0 0 2 2 2 1 Hypothetical methyltransferase Methyltransf_28 PF02636.12 EIE82663.1 - 0.003 17.0 0.0 0.0045 16.4 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.9 EIE82663.1 - 0.006 15.9 0.1 0.026 13.8 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase small domain Methyltransf_11 PF08241.7 EIE82664.1 - 1.8e-11 44.3 0.0 2.7e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIE82664.1 - 2.1e-10 40.4 0.1 3.7e-10 39.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIE82664.1 - 5.1e-09 36.4 0.0 8.7e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIE82664.1 - 1.7e-07 31.1 0.0 2.1e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIE82664.1 - 5.3e-07 30.0 0.0 1.3e-06 28.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIE82664.1 - 2.2e-05 23.6 0.0 4.4e-05 22.7 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EIE82664.1 - 0.00013 22.5 0.0 0.0002 21.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 EIE82664.1 - 0.00048 19.5 0.0 0.00067 19.0 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_8 PF05148.10 EIE82664.1 - 0.00062 19.4 0.1 0.002 17.8 0.1 1.7 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_4 PF02390.12 EIE82664.1 - 0.0012 17.9 0.0 0.0018 17.3 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_2 PF00891.13 EIE82664.1 - 0.0064 15.7 0.0 0.0068 15.6 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase MTS PF05175.9 EIE82664.1 - 0.067 12.5 0.0 0.098 12.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_26 PF13659.1 EIE82664.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Ski_Sno PF02437.12 EIE82665.1 - 0.031 13.8 0.0 0.058 12.9 0.0 1.5 1 0 0 1 1 1 0 SKI/SNO/DAC family SWIM PF04434.12 EIE82665.1 - 0.039 13.4 3.6 0.076 12.5 2.5 1.5 1 0 0 1 1 1 0 SWIM zinc finger Pox_MCEL PF03291.11 EIE82665.1 - 0.064 12.1 0.2 0.084 11.7 0.1 1.1 1 0 0 1 1 1 0 mRNA capping enzyme LEA_2 PF03168.8 EIE82667.1 - 0.0071 16.7 0.2 0.011 16.1 0.1 1.3 1 0 0 1 1 1 1 Late embryogenesis abundant protein Bac_export_3 PF01313.14 EIE82667.1 - 0.097 12.3 2.4 0.17 11.5 1.7 1.3 1 0 0 1 1 1 0 Bacterial export proteins, family 3 DUF4389 PF14333.1 EIE82667.1 - 1.1 9.0 3.4 1.8 8.3 2.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4389) Fungal_trans PF04082.13 EIE82668.1 - 1.7e-23 82.8 2.0 1.7e-23 82.8 1.4 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Aminotran_4 PF01063.14 EIE82669.1 - 7.9e-30 104.0 0.0 1e-29 103.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV MinE PF03776.9 EIE82669.1 - 0.15 11.5 0.1 0.38 10.2 0.0 1.6 2 0 0 2 2 2 0 Septum formation topological specificity factor MinE WD40 PF00400.27 EIE82670.1 - 2.3e-19 68.4 1.3 0.00025 20.8 0.0 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat eIF2A PF08662.6 EIE82670.1 - 0.0014 18.3 0.1 0.0034 17.1 0.0 1.7 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A zf-C2H2 PF00096.21 EIE82671.1 - 3.7e-07 30.0 24.5 6.7e-05 23.0 0.2 4.9 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIE82671.1 - 6.2e-07 29.4 18.3 6.8e-05 22.9 0.8 4.2 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EIE82671.1 - 0.0021 18.2 0.1 0.0021 18.2 0.1 4.9 5 0 0 5 5 5 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EIE82671.1 - 0.073 12.9 0.4 5.9 6.9 0.0 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger HAD PF12710.2 EIE82672.1 - 9.8e-19 68.2 0.1 3.7e-18 66.3 0.0 2.0 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EIE82672.1 - 8.4e-15 55.7 0.3 7.5e-13 49.3 0.2 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EIE82672.1 - 9.3e-14 51.1 0.0 2.7e-13 49.6 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EIE82672.1 - 0.00028 20.5 0.1 0.0038 16.8 0.0 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Glucosamine_iso PF01182.15 EIE82673.1 - 2.1e-22 79.8 0.0 3.3e-22 79.1 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Pox_ser-thr_kin PF05445.6 EIE82673.1 - 0.087 11.5 0.1 0.17 10.6 0.1 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase WD40 PF00400.27 EIE82674.1 - 5.6e-63 206.7 14.6 8.9e-10 38.0 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat HA2 PF04408.18 EIE82675.1 - 1.3e-14 54.0 0.0 1.4e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 Helicase associated domain (HA2) Epimerase PF01370.16 EIE82677.1 - 1.8e-52 178.1 0.0 2.6e-52 177.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EIE82677.1 - 6.8e-07 28.4 0.0 2.1e-05 23.5 0.0 2.1 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EIE82677.1 - 7.5e-06 25.0 0.3 0.00058 18.8 0.3 2.9 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EIE82677.1 - 0.014 14.1 0.0 0.038 12.6 0.0 1.8 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family RNR_N PF08343.5 EIE82677.1 - 0.016 15.0 0.0 0.049 13.4 0.0 1.9 1 0 0 1 1 1 0 Ribonucleotide reductase N-terminal NAD_binding_4 PF07993.7 EIE82677.1 - 0.1 11.4 0.2 1.1 8.1 0.0 2.0 2 0 0 2 2 2 0 Male sterility protein Glyco_transf_20 PF00982.16 EIE82678.1 - 3.9e-159 530.1 0.1 5.4e-159 529.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EIE82678.1 - 1.2e-75 253.4 0.0 2.1e-75 252.6 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Nicastrin PF05450.10 EIE82678.1 - 4.4e-27 94.8 0.4 3.2e-26 92.0 0.3 2.4 1 1 0 1 1 1 1 Nicastrin RRM_6 PF14259.1 EIE82679.1 - 4.7e-23 80.9 0.1 2.2e-11 43.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EIE82679.1 - 2.5e-20 71.8 0.5 4.1e-12 45.5 0.1 4.4 4 1 3 7 7 7 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE82679.1 - 5.7e-09 35.6 0.0 0.00085 19.1 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Abhydrolase_3 PF07859.8 EIE82680.1 - 4.1e-23 82.0 0.1 1.4e-22 80.3 0.0 1.8 1 1 1 2 2 2 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EIE82680.1 - 2.1e-07 29.9 0.0 1e-05 24.3 0.0 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF2424) Peptidase_S9 PF00326.16 EIE82680.1 - 0.0031 16.7 0.0 0.0057 15.9 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF2974 PF11187.3 EIE82680.1 - 0.023 14.0 0.0 0.047 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) APG6 PF04111.7 EIE82681.1 - 1.9e-129 431.2 10.1 2.7e-129 430.7 7.0 1.2 1 0 0 1 1 1 1 Autophagy protein Apg6 BH3 PF15285.1 EIE82681.1 - 3e-06 26.6 0.1 6.3e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Beclin-1 BH3 domain, Bcl-2-interacting TBPIP PF07106.8 EIE82681.1 - 0.033 13.7 15.3 0.067 12.7 10.6 1.5 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) V_ATPase_I PF01496.14 EIE82681.1 - 0.065 11.0 7.9 0.09 10.6 5.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Seryl_tRNA_N PF02403.17 EIE82681.1 - 0.24 11.4 12.2 0.81 9.7 8.4 2.0 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DNA_topoisoIV PF00521.15 EIE82681.1 - 0.31 9.8 9.9 0.48 9.2 6.9 1.2 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A zf-P11 PF03854.9 EIE82681.1 - 1.1 8.8 5.7 5.1 6.6 0.1 2.9 3 0 0 3 3 3 0 P-11 zinc finger DUF342 PF03961.8 EIE82681.1 - 1.7 6.9 15.0 1.2 7.5 9.1 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF342) DUF4407 PF14362.1 EIE82681.1 - 1.7 7.5 5.2 3 6.7 3.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4337 PF14235.1 EIE82681.1 - 6.4 6.5 12.2 6.3 6.6 6.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) DUF641 PF04859.7 EIE82681.1 - 6.8 6.4 13.0 5.6 6.7 7.4 2.0 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) AAA_23 PF13476.1 EIE82681.1 - 7.7 6.7 19.1 22 5.2 13.2 1.8 1 1 0 1 1 1 0 AAA domain EAP30 PF04157.11 EIE82682.1 - 1.5e-29 102.8 0.1 1.3e-28 99.7 0.0 1.8 1 1 1 2 2 2 1 EAP30/Vps36 family EF-hand_8 PF13833.1 EIE82682.1 - 0.043 13.4 0.1 0.14 11.7 0.0 1.9 2 0 0 2 2 2 0 EF-hand domain pair DUF3541 PF12060.3 EIE82682.1 - 0.089 12.0 0.1 1.5 8.1 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3541) Mem_trans PF03547.13 EIE82683.1 - 1.1e-37 129.2 13.8 5.4e-36 123.6 9.6 2.0 1 1 0 1 1 1 1 Membrane transport protein TPR_14 PF13428.1 EIE82685.1 - 2.6e-10 39.9 12.7 0.53 11.0 0.0 9.5 5 3 5 10 10 10 2 Tetratricopeptide repeat TPR_12 PF13424.1 EIE82685.1 - 3.6e-07 30.0 14.3 1.6 8.7 0.0 7.5 8 1 0 9 9 9 3 Tetratricopeptide repeat TPR_16 PF13432.1 EIE82685.1 - 3.9e-06 27.3 11.6 0.017 15.8 0.0 5.9 4 2 2 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.1 EIE82685.1 - 7.4e-06 25.5 14.2 0.065 12.8 0.0 7.5 6 4 3 9 9 9 2 TPR repeat NRDE-2 PF08424.5 EIE82685.1 - 5.3e-05 22.2 15.9 0.00021 20.3 3.8 4.4 1 1 3 4 4 4 2 NRDE-2, necessary for RNA interference SNAP PF14938.1 EIE82685.1 - 8.4e-05 21.8 2.8 0.0068 15.5 0.2 4.1 3 2 1 4 4 4 2 Soluble NSF attachment protein, SNAP TPR_19 PF14559.1 EIE82685.1 - 0.0013 19.0 9.0 1.8 8.9 0.0 6.0 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_2 PF07719.12 EIE82685.1 - 0.0053 16.5 17.6 7 6.8 0.0 8.8 11 0 0 11 11 11 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 EIE82685.1 - 0.41 10.4 19.7 2 8.2 0.6 6.1 5 3 0 5 5 5 0 Mad3/BUB1 homology region 1 HAT PF02184.11 EIE82685.1 - 2.3 8.0 11.0 5.4 6.8 0.1 5.8 7 0 0 7 7 7 0 HAT (Half-A-TPR) repeat TPR_8 PF13181.1 EIE82685.1 - 6.1 6.8 14.0 0.79 9.6 0.1 5.9 8 0 0 8 8 6 0 Tetratricopeptide repeat Ribosomal_S28e PF01200.13 EIE82688.1 - 5.7e-34 115.6 2.6 6.2e-34 115.5 1.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e ANTAR PF03861.9 EIE82689.1 - 0.004 16.7 0.1 0.0053 16.3 0.0 1.2 1 0 0 1 1 1 1 ANTAR domain MRP-S23 PF10484.4 EIE82689.1 - 0.062 13.1 0.1 0.067 13.1 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal protein S23 TAF8_C PF10406.4 EIE82689.1 - 0.072 13.1 0.2 0.11 12.5 0.2 1.3 1 0 0 1 1 1 0 Transcription factor TFIID complex subunit 8 C-term DENN PF02141.16 EIE82690.1 - 1.6e-06 27.9 0.1 2.8e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain Avl9 PF09794.4 EIE82690.1 - 0.0029 16.1 0.0 0.0046 15.4 0.0 1.3 1 0 0 1 1 1 1 Transport protein Avl9 SPA PF08616.5 EIE82690.1 - 0.0035 17.0 0.0 0.0069 16.0 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis DUF4243 PF14027.1 EIE82692.1 - 8.2e-60 202.9 0.1 2.3e-59 201.5 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF4243) Ribosomal_L18e PF00828.14 EIE82693.1 - 8e-25 87.6 0.2 1.2e-24 87.0 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 NNMT_PNMT_TEMT PF01234.12 EIE82693.1 - 0.051 12.5 0.0 0.076 11.9 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family SHMT PF00464.14 EIE82694.1 - 1.1e-203 676.0 0.0 1.3e-203 675.8 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Lipase_3 PF01764.20 EIE82695.1 - 6.8e-05 22.5 0.0 0.00018 21.1 0.0 1.7 2 0 0 2 2 2 1 Lipase (class 3) GLTP PF08718.6 EIE82696.1 - 7.7e-35 120.1 0.2 6.6e-18 65.1 0.0 2.3 1 1 1 2 2 2 2 Glycolipid transfer protein (GLTP) GatB_Yqey PF02637.13 EIE82696.1 - 0.019 14.7 0.0 0.31 10.7 0.0 2.1 2 0 0 2 2 2 0 GatB domain Alba PF01918.16 EIE82697.1 - 0.0021 17.5 0.2 0.0022 17.5 0.1 1.1 1 0 0 1 1 1 1 Alba ABC2_membrane PF01061.19 EIE82698.1 - 2.7e-34 118.2 14.3 2.7e-34 118.2 9.9 1.8 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 EIE82698.1 - 4.2e-26 91.8 0.0 6.7e-26 91.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EIE82698.1 - 6.3e-06 26.3 1.7 0.17 11.8 0.0 3.3 4 0 0 4 4 4 2 AAA domain DUF258 PF03193.11 EIE82698.1 - 5.5e-05 22.4 0.0 0.0001 21.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SMC_N PF02463.14 EIE82698.1 - 0.0013 18.0 0.0 0.013 14.7 0.0 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 EIE82698.1 - 0.0015 17.9 0.0 0.086 12.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EIE82698.1 - 0.0028 17.6 0.0 0.0045 16.9 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 EIE82698.1 - 0.0041 16.6 0.0 0.0086 15.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.2 EIE82698.1 - 0.005 15.9 24.6 0.06 12.3 15.8 2.7 2 1 0 2 2 2 1 ABC-2 family transporter protein AAA_22 PF13401.1 EIE82698.1 - 0.0082 16.2 0.0 0.017 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain SbcCD_C PF13558.1 EIE82698.1 - 0.0096 15.8 0.0 0.047 13.6 0.0 2.2 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_17 PF13207.1 EIE82698.1 - 0.059 14.1 0.0 0.13 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 EIE82698.1 - 0.066 11.8 0.0 0.11 11.1 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_18 PF13238.1 EIE82698.1 - 0.11 12.8 0.0 0.48 10.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 EIE82698.1 - 0.15 11.7 0.1 0.43 10.2 0.0 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EIE82698.1 - 0.16 11.8 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 EIE82698.1 - 0.19 10.4 0.1 0.3 9.8 0.0 1.2 1 0 0 1 1 1 0 ArgK protein Pkinase PF00069.20 EIE82699.1 - 1e-61 208.4 0.0 1.2e-61 208.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE82699.1 - 4.1e-23 81.7 0.0 6.5e-23 81.1 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE82699.1 - 9.8e-05 21.4 0.0 0.0032 16.4 0.0 2.3 2 0 0 2 2 2 1 Kinase-like AMMECR1 PF01871.12 EIE82699.1 - 0.012 14.7 0.0 0.43 9.6 0.0 2.2 2 0 0 2 2 2 0 AMMECR1 DUF1679 PF07914.6 EIE82699.1 - 0.063 11.8 0.7 0.12 11.0 0.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1679) APH PF01636.18 EIE82699.1 - 0.12 12.1 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family LRR_4 PF12799.2 EIE82700.1 - 1.8e-37 126.3 30.2 6.4e-06 25.6 2.8 9.1 6 2 2 9 9 9 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EIE82700.1 - 6.1e-30 102.7 45.0 5.2e-09 35.7 0.0 6.8 2 2 7 9 9 9 9 Leucine rich repeat LRR_1 PF00560.28 EIE82700.1 - 7e-24 80.1 28.0 0.058 13.4 0.4 13.8 14 1 1 15 15 15 8 Leucine Rich Repeat LRR_7 PF13504.1 EIE82700.1 - 2.2e-21 72.1 19.4 0.33 11.3 0.0 14.0 16 0 0 16 16 16 5 Leucine rich repeat LRR_6 PF13516.1 EIE82700.1 - 2.7e-17 60.8 21.4 0.1 12.7 0.0 12.6 11 1 1 12 12 12 3 Leucine Rich repeat LRR_9 PF14580.1 EIE82700.1 - 5.2e-05 22.8 8.9 0.023 14.2 0.5 3.8 2 2 1 3 3 3 2 Leucine-rich repeat DUF4662 PF15578.1 EIE82700.1 - 0.04 13.5 0.2 0.078 12.5 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4662) LRR_3 PF07725.7 EIE82700.1 - 0.6 9.9 11.3 1.9 8.3 0.2 4.5 4 0 0 4 4 4 0 Leucine Rich Repeat DUF2457 PF10446.4 EIE82701.1 - 3.9 6.0 7.8 5.1 5.7 5.2 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2457) DUF2348 PF09807.4 EIE82702.1 - 8.4e-11 41.4 0.1 8.4e-11 41.4 0.1 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2348) Elong_Iki1 PF10483.4 EIE82702.1 - 0.015 14.6 0.0 0.017 14.4 0.0 1.0 1 0 0 1 1 1 0 Elongator subunit Iki1 CI-B14_5a PF07347.7 EIE82703.1 - 0.0019 17.8 0.1 0.0032 17.1 0.1 1.4 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) DUF2363 PF10155.4 EIE82704.1 - 9.7e-14 51.3 1.9 1.5e-13 50.7 0.7 1.6 1 1 1 2 2 2 1 Uncharacterized conserved protein (DUF2363) NUDIX PF00293.23 EIE82706.1 - 7e-31 106.6 0.0 9e-31 106.3 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain Nup96 PF12110.3 EIE82707.1 - 0.12 11.4 0.0 9.6 5.2 0.0 2.1 2 0 0 2 2 2 0 Nuclear protein 96 Mito_carr PF00153.22 EIE82708.1 - 7e-70 230.8 3.4 9.8e-24 82.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein RNA12 PF10443.4 EIE82709.1 - 1.2e-91 307.4 3.1 1.3e-90 304.0 2.1 2.1 1 1 0 1 1 1 1 RNA12 protein RRM_1 PF00076.17 EIE82709.1 - 3.1e-05 23.4 0.0 9e-05 22.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE82709.1 - 0.00022 21.1 0.0 0.00064 19.6 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE82709.1 - 0.00032 20.4 0.0 0.00093 18.9 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.20 EIE82710.1 - 7.3e-10 38.4 0.7 2e-09 36.9 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE82710.1 - 0.0014 17.7 0.2 0.019 14.0 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Sugar_tr PF00083.19 EIE82711.1 - 1.3e-42 145.9 24.2 2.4e-25 89.0 4.0 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EIE82711.1 - 1e-15 57.3 37.0 4.1e-09 35.6 10.0 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily VD10_N PF08476.5 EIE82711.1 - 0.19 11.1 0.5 1.6 8.3 0.2 2.3 2 0 0 2 2 2 0 Viral D10 N-terminal HTH_IclR PF09339.5 EIE82712.1 - 0.018 14.5 0.0 0.023 14.2 0.0 1.1 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_28 PF13518.1 EIE82712.1 - 0.034 14.1 0.0 0.039 13.9 0.0 1.1 1 0 0 1 1 1 0 Helix-turn-helix domain MCPsignal PF00015.16 EIE82712.1 - 0.035 13.6 0.2 0.037 13.5 0.1 1.0 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain HTH_23 PF13384.1 EIE82712.1 - 0.072 12.7 0.0 0.088 12.4 0.0 1.1 1 0 0 1 1 1 0 Homeodomain-like domain SpoIIID PF12116.3 EIE82712.1 - 0.11 12.4 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 Stage III sporulation protein D Arrestin_C PF02752.17 EIE82715.1 - 5.7e-12 45.9 1.1 5.7e-12 45.9 0.8 2.3 3 0 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EIE82715.1 - 3.8e-09 36.5 2.2 1.9e-07 30.9 0.0 2.8 2 1 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 EIE82715.1 - 0.023 14.1 0.1 0.057 12.9 0.1 1.6 1 1 0 1 1 1 0 Arrestin_N terminal like DUF1473 PF07341.6 EIE82717.1 - 0.038 13.5 0.5 0.047 13.2 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1473) YscO PF07321.7 EIE82717.1 - 0.13 12.0 4.6 0.17 11.7 3.2 1.3 1 0 0 1 1 1 0 Type III secretion protein YscO zf-CCHC_4 PF14392.1 EIE82718.1 - 0.004 16.7 6.3 0.4 10.3 0.6 2.6 2 0 0 2 2 2 2 Zinc knuckle zinc-ribbons_6 PF07191.7 EIE82718.1 - 0.25 11.1 5.5 0.97 9.2 1.2 2.2 1 1 1 2 2 2 0 zinc-ribbons MFS_1 PF07690.11 EIE82719.1 - 5.2e-28 97.7 46.3 4.3e-21 75.0 14.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIE82719.1 - 8.4e-05 21.3 35.4 0.001 17.7 9.8 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.2 EIE82719.1 - 0.011 15.4 2.0 0.021 14.6 0.2 2.4 2 0 0 2 2 2 0 MFS_1 like family TauD PF02668.11 EIE82721.1 - 6.8e-57 193.0 1.1 8.3e-57 192.7 0.8 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DDE_3 PF13358.1 EIE82722.1 - 9.4e-10 38.4 0.0 9.4e-10 38.4 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF2363 PF10155.4 EIE82723.1 - 6.2e-14 52.0 2.0 9.2e-14 51.4 0.7 1.6 1 1 1 2 2 2 1 Uncharacterized conserved protein (DUF2363) DNA_ligase_A_M PF01068.16 EIE82724.1 - 6.4e-24 84.4 1.0 1e-23 83.7 0.7 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_OB_2 PF14743.1 EIE82724.1 - 9.5e-07 28.3 0.0 1.8e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 DNA ligase OB-like domain mRNA_cap_enzyme PF01331.14 EIE82724.1 - 5.8e-06 26.1 1.1 6.2e-05 22.7 0.7 2.5 1 1 0 1 1 1 1 mRNA capping enzyme, catalytic domain DNA_ligase_A_N PF04675.9 EIE82724.1 - 0.017 14.9 0.0 0.059 13.1 0.0 1.9 2 0 0 2 2 2 0 DNA ligase N terminus PQ-loop PF04193.9 EIE82725.1 - 4e-14 51.8 0.9 4e-14 51.8 0.7 3.3 4 0 0 4 4 4 1 PQ loop repeat ER_lumen_recept PF00810.13 EIE82725.1 - 0.07 13.6 6.4 0.03 14.7 2.6 1.8 1 1 1 2 2 2 0 ER lumen protein retaining receptor CCDC14 PF15254.1 EIE82727.1 - 0.00031 19.2 0.3 0.00035 19.1 0.2 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 14 MscS_porin PF12795.2 EIE82727.1 - 0.0099 15.2 6.6 0.011 15.0 4.6 1.0 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain Flg_hook PF02120.11 EIE82727.1 - 0.018 14.7 4.8 0.024 14.2 3.3 1.2 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK CENP-F_leu_zip PF10473.4 EIE82727.1 - 0.018 14.8 1.0 0.021 14.6 0.7 1.1 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Mnd1 PF03962.10 EIE82727.1 - 0.039 13.6 0.3 0.046 13.3 0.2 1.1 1 0 0 1 1 1 0 Mnd1 family IncA PF04156.9 EIE82727.1 - 0.079 12.5 2.5 0.084 12.4 1.7 1.1 1 0 0 1 1 1 0 IncA protein Cas_Cas02710 PF09670.5 EIE82727.1 - 0.08 11.5 0.1 0.089 11.4 0.1 1.0 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas02710) DUF972 PF06156.8 EIE82727.1 - 0.084 13.2 0.2 0.14 12.5 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Dict-STAT-coil PF09267.5 EIE82727.1 - 0.12 12.5 4.2 0.14 12.3 2.9 1.1 1 0 0 1 1 1 0 Dictyostelium STAT, coiled coil TBPIP PF07106.8 EIE82727.1 - 0.15 11.6 0.8 0.16 11.4 0.5 1.1 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) ACOX PF01756.14 EIE82728.1 - 3.3e-42 143.9 0.0 6.5e-42 143.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 EIE82728.1 - 5.1e-26 91.4 2.6 1.1e-25 90.3 1.8 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 EIE82728.1 - 1.2e-10 40.6 0.1 2.9e-10 39.5 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 EIE82728.1 - 1.8e-05 24.9 0.0 0.00017 21.7 0.0 2.5 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain RTP801_C PF07809.6 EIE82729.1 - 0.012 15.2 0.1 0.013 15.2 0.0 1.1 1 0 0 1 1 1 0 RTP801 C-terminal region DUF2828 PF11443.3 EIE82730.1 - 9.6e-135 449.7 2.8 1.2e-134 449.4 1.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) DUF2552 PF10827.3 EIE82730.1 - 0.029 14.3 0.0 0.3 11.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2552) CENP-B_dimeris PF09026.5 EIE82730.1 - 3.1 8.1 9.3 9.4 6.5 6.5 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain B-block_TFIIIC PF04182.7 EIE82731.1 - 6.7e-12 45.0 2.1 2.1e-10 40.3 0.2 3.2 3 0 0 3 3 3 1 B-block binding subunit of TFIIIC Myb_DNA-bind_6 PF13921.1 EIE82731.1 - 1.9e-05 24.6 1.6 0.00026 21.0 0.7 3.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EIE82731.1 - 0.0055 16.7 0.3 0.021 14.8 0.2 2.1 1 0 0 1 1 1 1 Myb-like DNA-binding domain HTH_27 PF13463.1 EIE82731.1 - 0.052 13.8 0.2 0.68 10.3 0.0 3.1 4 0 0 4 4 4 0 Winged helix DNA-binding domain Fungal_trans PF04082.13 EIE82732.1 - 5.7e-19 67.9 0.1 1.9e-18 66.3 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain YyzF PF14116.1 EIE82732.1 - 0.13 12.2 0.2 0.35 10.8 0.1 1.7 1 0 0 1 1 1 0 YyzF-like protein HTH_Tnp_Tc3_2 PF01498.13 EIE82733.1 - 1.3e-09 37.9 0.1 2.1e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Transposase Complex1_LYR PF05347.10 EIE82734.1 - 1.9e-10 40.4 1.2 2.3e-10 40.0 0.8 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EIE82734.1 - 1.7e-09 37.7 0.6 2.1e-09 37.4 0.4 1.2 1 0 0 1 1 1 1 Complex1_LYR-like WD40 PF00400.27 EIE82735.1 - 1.3e-07 31.1 4.5 0.034 14.0 0.0 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat DUF2183 PF09949.4 EIE82736.1 - 1.7e-19 69.5 0.6 2.3e-18 65.9 0.1 2.4 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) eRF1_2 PF03464.10 EIE82736.1 - 0.077 13.3 0.1 0.17 12.2 0.0 1.6 2 0 0 2 2 2 0 eRF1 domain 2 SAE2 PF08573.5 EIE82737.1 - 9.1e-05 23.0 2.5 9.1e-05 23.0 1.7 4.2 2 2 0 2 2 2 1 DNA repair protein endonuclease SAE2/CtIP C-terminus CTP_transf_2 PF01467.21 EIE82737.1 - 0.069 13.2 3.6 0.12 12.4 2.5 1.4 1 0 0 1 1 1 0 Cytidylyltransferase Otopetrin PF03189.8 EIE82737.1 - 6.7 5.5 10.4 14 4.5 7.3 1.6 1 1 0 1 1 1 0 Otopetrin Atg14 PF10186.4 EIE82737.1 - 7 5.4 26.9 9.9 4.9 18.0 1.7 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 eIF3_N PF09440.5 EIE82738.1 - 0.068 13.3 0.2 0.068 13.3 0.2 1.5 2 0 0 2 2 2 0 eIF3 subunit 6 N terminal domain GTP_cyclohydro2 PF00925.15 EIE82739.1 - 2.2e-65 219.0 0.3 7.8e-60 200.9 0.2 2.2 2 0 0 2 2 2 2 GTP cyclohydrolase II GN3L_Grn1 PF08701.6 EIE82740.1 - 2.1e-20 72.4 25.0 2.1e-20 72.4 17.3 1.8 1 1 0 1 1 1 1 GNL3L/Grn1 putative GTPase Ebola_NP PF05505.7 EIE82740.1 - 0.6 8.0 7.6 0.63 8.0 5.3 1.0 1 0 0 1 1 1 0 Ebola nucleoprotein DUF4407 PF14362.1 EIE82740.1 - 6.2 5.6 8.9 9.5 5.0 6.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Phytochelatin PF05023.9 EIE82741.1 - 7.8e-65 217.8 0.0 3.5e-37 127.4 0.0 2.3 1 1 1 2 2 2 2 Phytochelatin synthase Peptidase_C39_2 PF13529.1 EIE82741.1 - 0.008 16.5 0.0 0.11 12.9 0.0 2.4 2 0 0 2 2 2 1 Peptidase_C39 like family DUF2613 PF11021.3 EIE82745.1 - 0.56 9.9 3.4 0.28 10.9 1.2 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) CYSTM PF12734.2 EIE82746.1 - 1.1e-07 31.7 20.7 1.1e-07 31.7 14.4 4.9 1 1 1 2 2 2 1 Cysteine-rich TM module stress tolerance Fer2_4 PF13510.1 EIE82747.1 - 0.049 13.4 0.0 0.063 13.0 0.0 1.2 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Velvet PF11754.3 EIE82748.1 - 9.5e-50 169.0 0.1 2.3e-49 167.7 0.0 1.6 1 0 0 1 1 1 1 Velvet factor Glyco_transf_49 PF13896.1 EIE82748.1 - 3.8e-23 82.0 0.1 1.6e-14 53.7 0.0 2.4 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan SCAMP PF04144.8 EIE82748.1 - 0.11 12.3 0.3 0.37 10.6 0.0 1.9 2 0 0 2 2 2 0 SCAMP family RabGAP-TBC PF00566.13 EIE82749.1 - 2.1e-33 115.5 0.4 2.1e-33 115.5 0.3 2.4 3 0 0 3 3 3 1 Rab-GTPase-TBC domain START PF01852.14 EIE82750.1 - 9.9e-11 41.3 0.1 3e-10 39.7 0.0 1.7 2 0 0 2 2 2 1 START domain PHD PF00628.24 EIE82753.1 - 4.1e-11 42.4 7.1 8.4e-11 41.3 4.9 1.6 1 0 0 1 1 1 1 PHD-finger zf-CpG_bind_C PF12269.3 EIE82753.1 - 2.5e-05 23.8 6.4 0.00015 21.3 4.1 2.2 1 1 1 2 2 2 1 CpG binding protein zinc finger C terminal domain zf-RING_2 PF13639.1 EIE82753.1 - 0.28 11.0 3.2 1.1 9.1 1.2 2.3 2 0 0 2 2 2 0 Ring finger domain Kinesin PF00225.18 EIE82754.1 - 3.9e-23 81.6 0.6 3.9e-23 81.6 0.4 2.4 2 1 0 2 2 1 1 Kinesin motor domain Myosin_tail_1 PF01576.14 EIE82754.1 - 2.6e-05 22.2 22.1 3.7e-05 21.6 15.3 1.1 1 0 0 1 1 1 1 Myosin tail IncA PF04156.9 EIE82754.1 - 2.6e-05 23.8 21.0 0.049 13.2 12.6 2.5 1 1 1 2 2 2 2 IncA protein Macoilin PF09726.4 EIE82754.1 - 0.00016 20.1 12.0 0.00016 20.1 8.3 2.1 1 1 1 2 2 2 1 Transmembrane protein DUF745 PF05335.8 EIE82754.1 - 0.00072 19.1 11.9 0.069 12.6 0.8 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF745) GAS PF13851.1 EIE82754.1 - 0.0017 17.6 13.9 0.0017 17.6 9.6 2.5 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.4 EIE82754.1 - 0.0029 17.4 26.6 0.11 12.3 11.9 2.6 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF869 PF05911.6 EIE82754.1 - 0.0063 14.8 17.8 0.0081 14.4 12.3 1.1 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) TPR_MLP1_2 PF07926.7 EIE82754.1 - 0.0068 16.1 13.7 0.0068 16.1 9.5 2.9 1 1 2 3 3 3 1 TPR/MLP1/MLP2-like protein Spc7 PF08317.6 EIE82754.1 - 0.0075 14.9 4.2 0.0075 14.9 2.9 2.2 1 1 1 2 2 2 1 Spc7 kinetochore protein Laminin_II PF06009.7 EIE82754.1 - 0.017 14.8 3.7 0.017 14.8 2.6 2.6 1 1 0 2 2 2 0 Laminin Domain II Reo_sigmaC PF04582.7 EIE82754.1 - 0.019 14.1 7.9 0.67 9.0 0.6 2.3 1 1 1 2 2 2 0 Reovirus sigma C capsid protein V_ATPase_I PF01496.14 EIE82754.1 - 0.034 12.0 21.2 0.0056 14.6 6.9 2.1 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Baculo_PEP_C PF04513.7 EIE82754.1 - 0.065 13.0 7.0 0.16 11.7 0.5 2.7 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Filament PF00038.16 EIE82754.1 - 0.081 12.3 22.6 0.061 12.7 10.6 2.2 1 1 1 2 2 2 0 Intermediate filament protein Tropomyosin PF00261.15 EIE82754.1 - 0.18 10.8 25.4 0.043 12.8 7.6 2.3 1 1 1 2 2 2 0 Tropomyosin PEP-utilisers_N PF05524.8 EIE82754.1 - 0.25 11.1 7.5 0.085 12.6 1.5 2.4 1 1 0 2 2 2 0 PEP-utilising enzyme, N-terminal NPV_P10 PF05531.7 EIE82754.1 - 0.28 11.4 7.5 4.8 7.5 0.4 3.5 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein Nup54 PF13874.1 EIE82754.1 - 0.32 10.6 12.2 0.039 13.6 4.2 2.6 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 TMF_DNA_bd PF12329.3 EIE82754.1 - 0.34 10.7 23.5 0.16 11.7 6.4 4.2 2 2 0 3 3 3 0 TATA element modulatory factor 1 DNA binding ATG16 PF08614.6 EIE82754.1 - 0.54 10.0 22.8 0.12 12.1 6.0 2.8 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) CALCOCO1 PF07888.6 EIE82754.1 - 0.66 8.1 18.8 0.94 7.6 13.0 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like HalX PF08663.5 EIE82754.1 - 0.73 9.8 12.0 0.6 10.1 0.1 4.1 2 1 1 4 4 3 0 HalX domain DUF972 PF06156.8 EIE82754.1 - 0.84 10.0 20.9 15 5.9 0.0 4.5 2 1 1 3 3 3 0 Protein of unknown function (DUF972) Lectin_N PF03954.9 EIE82754.1 - 1.8 7.9 10.2 0.44 9.9 0.4 3.1 1 1 2 3 3 3 0 Hepatic lectin, N-terminal domain DUF4201 PF13870.1 EIE82754.1 - 2.2 7.6 23.8 9.4 5.6 7.4 3.4 1 1 1 3 3 3 0 Domain of unknown function (DUF4201) Occludin_ELL PF07303.8 EIE82754.1 - 2.3 8.9 16.6 8 7.2 2.6 4.0 1 1 3 4 4 4 0 Occludin homology domain DUF4200 PF13863.1 EIE82754.1 - 3 7.8 24.6 1.2 9.1 7.6 3.2 1 1 1 3 3 3 0 Domain of unknown function (DUF4200) Seryl_tRNA_N PF02403.17 EIE82754.1 - 4.6 7.2 20.7 0.53 10.3 2.1 3.6 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain ADIP PF11559.3 EIE82754.1 - 4.7 7.1 25.1 0.036 13.9 1.8 3.5 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Peptidase_S64 PF08192.6 EIE82754.1 - 5.3 5.2 14.5 1.4 7.1 7.3 1.7 1 1 1 2 2 2 0 Peptidase family S64 APG6 PF04111.7 EIE82754.1 - 6.4 5.7 27.1 0.75 8.7 10.2 2.3 1 1 1 2 2 2 0 Autophagy protein Apg6 Atg14 PF10186.4 EIE82754.1 - 9.7 5.0 18.0 2.5 6.9 7.8 2.2 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Thg1C PF14413.1 EIE82755.1 - 3e-48 162.4 0.3 4e-48 162.0 0.2 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.7 EIE82755.1 - 1.5e-25 89.3 0.4 2.2e-25 88.8 0.3 1.3 1 0 0 1 1 1 1 tRNAHis guanylyltransferase DUF1912 PF08930.5 EIE82755.1 - 0.087 12.9 0.1 0.7 10.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1912) Nop10p PF04135.7 EIE82756.1 - 7.9e-23 79.9 0.7 9.6e-23 79.6 0.5 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family GATA PF00320.22 EIE82757.1 - 5.1e-17 60.9 4.3 1.2e-16 59.7 3.0 1.7 1 0 0 1 1 1 1 GATA zinc finger RRN7 PF11781.3 EIE82757.1 - 0.00019 20.8 0.6 0.00019 20.8 0.4 1.9 2 0 0 2 2 2 1 RNA polymerase I-specific transcription initiation factor Rrn7 TF_Zn_Ribbon PF08271.7 EIE82757.1 - 0.005 16.1 10.4 0.0072 15.6 0.4 2.6 3 0 0 3 3 3 2 TFIIB zinc-binding Cas_CXXC_CXXC PF09706.5 EIE82757.1 - 0.0076 16.3 2.3 0.0076 16.3 1.6 2.3 2 0 0 2 2 2 1 CRISPR-associated protein (Cas_CXXC_CXXC) DUF2365 PF10157.4 EIE82757.1 - 0.009 15.9 1.1 0.014 15.2 0.7 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2365) IncA PF04156.9 EIE82757.1 - 0.018 14.6 2.5 0.035 13.7 1.7 1.5 1 0 0 1 1 1 0 IncA protein eIF-5_eIF-2B PF01873.12 EIE82757.1 - 0.024 14.3 7.3 0.22 11.1 4.8 2.4 1 1 1 2 2 2 0 Domain found in IF2B/IF5 Chloroplast_duf PF14476.1 EIE82757.1 - 0.07 11.9 0.1 0.098 11.4 0.1 1.2 1 0 0 1 1 1 0 Petal formation-expressed COX5B PF01215.14 EIE82757.1 - 0.11 12.1 2.1 0.13 11.9 0.2 2.1 2 1 0 3 3 3 0 Cytochrome c oxidase subunit Vb DUF2205 PF10224.4 EIE82757.1 - 0.15 11.6 4.7 0.12 11.9 1.2 2.2 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) DZR PF12773.2 EIE82757.1 - 0.78 9.6 13.6 40 4.1 2.7 3.1 1 1 1 2 2 2 0 Double zinc ribbon AATF-Che1 PF13339.1 EIE82757.1 - 1.4 9.1 10.4 0.16 12.1 2.1 2.5 2 1 1 3 3 3 0 Apoptosis antagonizing transcription factor DnaJ_CXXCXGXG PF00684.14 EIE82757.1 - 7.1 6.7 12.9 29 4.8 8.2 2.4 1 1 1 2 2 2 0 DnaJ central domain PP2C PF00481.16 EIE82758.1 - 7.5e-55 186.0 1.2 7.9e-55 185.9 0.0 1.6 2 0 0 2 2 2 1 Protein phosphatase 2C LRR_4 PF12799.2 EIE82758.1 - 1.5e-43 145.7 70.1 1.6e-05 24.3 0.3 12.6 5 3 7 13 13 13 13 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EIE82758.1 - 1.6e-34 117.4 54.5 1.1e-06 28.3 0.3 8.3 3 2 4 8 8 8 8 Leucine rich repeat Guanylate_cyc PF00211.15 EIE82758.1 - 2.1e-30 105.4 0.0 3.8e-30 104.6 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.28 EIE82758.1 - 1.7e-21 72.9 59.1 0.084 12.9 2.2 17.9 17 1 1 18 18 18 8 Leucine Rich Repeat LRR_7 PF13504.1 EIE82758.1 - 3.3e-11 41.4 54.8 0.24 11.7 1.3 17.1 17 0 0 17 17 17 3 Leucine rich repeat LRR_9 PF14580.1 EIE82758.1 - 5.7e-05 22.7 9.2 0.00053 19.6 0.0 3.5 2 1 1 3 3 3 2 Leucine-rich repeat LRR_6 PF13516.1 EIE82758.1 - 0.03 14.3 51.2 3.3 8.0 0.6 13.8 15 0 0 15 15 15 0 Leucine Rich repeat RA PF00788.18 EIE82758.1 - 0.047 14.1 0.0 0.14 12.6 0.0 1.7 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain vATP-synt_AC39 PF01992.11 EIE82759.1 - 2.4e-104 349.1 0.0 2.7e-104 348.9 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit DUF496 PF04363.7 EIE82759.1 - 0.13 12.0 0.5 2.7 7.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF496) Pkinase PF00069.20 EIE82760.1 - 1.4e-56 191.5 0.0 1.9e-54 184.5 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE82760.1 - 9.8e-43 146.0 0.0 7.4e-42 143.1 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE82760.1 - 1.3e-09 37.4 0.0 3.2e-09 36.1 0.0 1.6 2 0 0 2 2 2 1 Kinase-like zf-CCCH PF00642.19 EIE82761.1 - 1.3e-19 69.4 16.9 1.1e-10 40.9 2.0 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) W2 PF02020.13 EIE82761.1 - 1.3e-09 37.8 5.0 1.3e-09 37.8 3.5 2.3 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon NUDIX PF00293.23 EIE82761.1 - 3.1e-08 33.3 0.0 6.5e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain zf-CCCH_2 PF14608.1 EIE82761.1 - 2 8.5 12.4 5.2 7.2 1.0 2.6 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type RasGEF PF00617.14 EIE82762.1 - 2.8e-19 69.5 0.9 5.3e-19 68.6 0.3 1.7 2 0 0 2 2 2 1 RasGEF domain Fungal_trans PF04082.13 EIE82765.1 - 9.2e-25 86.9 1.6 1.5e-24 86.2 1.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain BTB PF00651.26 EIE82766.1 - 3.1e-12 46.4 0.3 6.3e-12 45.4 0.2 1.5 1 0 0 1 1 1 1 BTB/POZ domain Clathrin PF00637.15 EIE82767.1 - 7.2e-209 683.7 42.7 1.9e-36 124.8 0.0 7.5 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.1 EIE82767.1 - 9.3e-31 105.5 0.2 4.8e-30 103.2 0.2 2.4 1 0 0 1 1 1 1 Clathrin-H-link Clathrin_propel PF01394.15 EIE82767.1 - 8.8e-26 88.4 2.2 0.00039 20.5 0.0 7.4 7 0 0 7 7 7 5 Clathrin propeller repeat Clathrin-link PF09268.5 EIE82767.1 - 1.4e-09 36.7 0.2 3.4e-09 35.5 0.1 1.7 1 0 0 1 1 1 1 Clathrin, heavy-chain linker Coatomer_WDAD PF04053.9 EIE82767.1 - 7.7e-08 31.5 5.1 7.9e-05 21.6 0.0 3.9 4 0 0 4 4 4 2 Coatomer WD associated region TPR_12 PF13424.1 EIE82767.1 - 2.1e-05 24.3 9.0 1.5 8.7 0.0 7.1 7 1 0 7 7 7 1 Tetratricopeptide repeat TPR_1 PF00515.23 EIE82767.1 - 7.2e-05 22.2 6.6 1.8 8.3 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 EIE82767.1 - 0.0001 22.6 2.3 31 5.5 0.0 7.6 10 0 0 10 10 8 0 Tetratricopeptide repeat TPR_2 PF07719.12 EIE82767.1 - 0.00013 21.5 2.4 1.8 8.7 0.0 5.7 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 EIE82767.1 - 0.01 15.4 7.5 25 4.6 0.1 6.4 7 1 0 7 7 7 0 TPR repeat TPR_7 PF13176.1 EIE82767.1 - 0.11 12.3 10.8 5.4 7.0 0.0 7.1 7 1 1 8 8 8 0 Tetratricopeptide repeat Hormone_3 PF00159.13 EIE82768.1 - 2.7 8.0 0.1 2.7 8.0 0.0 3.1 3 1 1 4 4 4 0 Pancreatic hormone peptide Peptidase_C12 PF01088.16 EIE82769.1 - 3.2e-45 153.9 1.8 1.4e-41 142.0 0.3 2.0 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase, family 1 R3H PF01424.17 EIE82770.1 - 1.3e-11 43.9 0.1 1.8e-11 43.5 0.1 1.2 1 0 0 1 1 1 1 R3H domain Mso1_Sec1_bdg PF14475.1 EIE82771.1 - 9.4e-07 28.1 0.1 2.7e-06 26.6 0.1 1.8 1 0 0 1 1 1 1 Sec1-binding region of Mso1 BRCT_assoc PF12820.2 EIE82771.1 - 0.015 15.0 0.6 0.034 13.8 0.4 1.6 1 0 0 1 1 1 0 Serine-rich domain associated with BRCT VTC PF09359.5 EIE82772.1 - 6.4e-86 287.8 2.4 1.1e-85 287.0 1.7 1.4 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 EIE82772.1 - 2.6e-11 43.8 18.4 7.3e-06 25.9 0.3 4.0 3 1 2 5 5 5 3 SPX domain DUF202 PF02656.10 EIE82772.1 - 2.2e-06 27.7 1.9 4.7e-06 26.7 1.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF202) VTC PF09359.5 EIE82773.1 - 1.2e-73 247.5 2.5 1.2e-73 247.5 1.7 2.2 2 1 0 2 2 2 1 VTC domain SPX PF03105.14 EIE82773.1 - 1e-15 58.3 16.9 4.5e-09 36.4 0.4 4.0 2 2 1 3 3 3 2 SPX domain DUF202 PF02656.10 EIE82773.1 - 2.3e-09 37.3 3.2 4e-09 36.5 2.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF202) JAB PF01398.16 EIE82774.1 - 5e-31 106.7 0.0 1.1e-30 105.6 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EIE82774.1 - 3e-29 101.4 2.9 5.5e-29 100.5 2.0 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 EIE82774.1 - 3e-07 29.9 0.0 4.8e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Mito_carr PF00153.22 EIE82775.1 - 1.4e-05 24.6 0.1 1.5e-05 24.6 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial carrier protein RA PF00788.18 EIE82776.1 - 3.9e-13 49.6 0.2 2.9e-08 34.0 0.0 3.1 2 1 0 2 2 2 2 Ras association (RalGDS/AF-6) domain DUF3453 PF11935.3 EIE82777.1 - 0.034 13.5 0.7 1.3 8.3 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3453) zf-C2H2 PF00096.21 EIE82777.1 - 0.49 10.8 3.2 3.5 8.1 0.4 3.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type ABC_tran PF00005.22 EIE82778.1 - 3.1e-45 153.8 0.0 6.3e-23 81.5 0.0 3.9 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EIE82778.1 - 4.4e-14 53.1 3.9 0.00087 19.3 0.0 4.8 3 2 1 4 4 3 3 AAA domain SMC_N PF02463.14 EIE82778.1 - 2.5e-13 49.7 0.0 0.012 14.8 0.0 4.4 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EIE82778.1 - 1.4e-08 35.6 0.2 0.001 19.8 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_28 PF13521.1 EIE82778.1 - 7.2e-08 32.5 0.1 0.028 14.3 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EIE82778.1 - 8.2e-08 31.6 0.0 0.011 15.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 EIE82778.1 - 1.7e-07 31.4 0.0 0.019 15.0 0.0 4.2 5 0 0 5 5 4 2 AAA domain DUF258 PF03193.11 EIE82778.1 - 4e-07 29.3 0.0 0.0015 17.7 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA PF00004.24 EIE82778.1 - 8e-07 29.3 0.4 0.047 13.8 0.0 4.2 5 0 0 5 5 3 2 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 EIE82778.1 - 2e-06 27.7 0.0 0.016 15.1 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 EIE82778.1 - 2.4e-06 28.0 0.0 0.12 12.9 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_15 PF13175.1 EIE82778.1 - 2.4e-06 26.8 0.0 0.5 9.3 0.0 3.8 3 0 0 3 3 3 2 AAA ATPase domain NACHT PF05729.7 EIE82778.1 - 4.9e-06 26.2 0.0 0.045 13.4 0.0 3.5 3 0 0 3 3 3 2 NACHT domain SbcCD_C PF13558.1 EIE82778.1 - 7.2e-06 25.8 0.0 0.0094 15.8 0.0 3.0 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 EIE82778.1 - 7.6e-06 26.2 0.8 0.14 12.4 0.0 3.7 3 0 0 3 3 3 2 AAA domain ArgK PF03308.11 EIE82778.1 - 1.1e-05 24.3 0.1 0.048 12.4 0.0 2.5 2 0 0 2 2 2 2 ArgK protein RNA_helicase PF00910.17 EIE82778.1 - 1.7e-05 24.9 0.0 0.26 11.4 0.0 2.8 2 0 0 2 2 2 2 RNA helicase MobB PF03205.9 EIE82778.1 - 2.6e-05 23.9 0.0 0.14 11.8 0.0 2.8 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B Chromo PF00385.19 EIE82778.1 - 2.8e-05 23.6 2.0 5.6e-05 22.7 0.1 2.5 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain HEAT_2 PF13646.1 EIE82778.1 - 3.2e-05 24.1 0.3 1.4 9.2 0.1 3.9 1 1 2 3 3 3 1 HEAT repeats AAA_16 PF13191.1 EIE82778.1 - 3.5e-05 23.8 0.2 0.06 13.3 0.0 3.1 3 1 0 3 3 2 1 AAA ATPase domain AAA_33 PF13671.1 EIE82778.1 - 6.7e-05 22.7 0.0 0.39 10.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF815 PF05673.8 EIE82778.1 - 9.7e-05 21.4 0.0 0.2 10.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Zeta_toxin PF06414.7 EIE82778.1 - 0.00015 20.9 0.3 2.6 7.0 0.0 4.1 4 0 0 4 4 4 1 Zeta toxin AAA_14 PF13173.1 EIE82778.1 - 0.00018 21.4 0.0 0.17 11.8 0.0 3.1 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EIE82778.1 - 0.00018 21.0 0.0 0.51 9.7 0.0 2.9 3 0 0 3 3 2 2 AAA-like domain AAA_30 PF13604.1 EIE82778.1 - 0.00029 20.4 0.1 1.7 8.1 0.0 3.6 3 0 0 3 3 3 1 AAA domain PduV-EutP PF10662.4 EIE82778.1 - 0.00046 19.7 0.0 0.64 9.4 0.0 2.8 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation HEAT PF02985.17 EIE82778.1 - 0.00071 19.4 0.2 1.9 8.7 0.0 4.1 3 0 0 3 3 3 1 HEAT repeat Arch_ATPase PF01637.13 EIE82778.1 - 0.00081 19.1 0.6 0.87 9.2 0.0 3.7 3 0 0 3 3 3 1 Archaeal ATPase ATP-synt_ab PF00006.20 EIE82778.1 - 0.00098 18.6 0.0 0.22 10.9 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_25 PF13481.1 EIE82778.1 - 0.0015 17.9 0.2 5.4 6.3 0.0 4.1 5 0 0 5 5 5 0 AAA domain AAA_23 PF13476.1 EIE82778.1 - 0.0016 18.7 11.9 0.14 12.4 0.6 3.6 4 1 0 4 4 3 2 AAA domain Dynamin_N PF00350.18 EIE82778.1 - 0.0025 17.6 0.1 0.51 10.1 0.0 2.9 3 0 0 3 3 2 1 Dynamin family CLASP_N PF12348.3 EIE82778.1 - 0.0073 15.6 0.3 0.015 14.7 0.2 1.5 1 0 0 1 1 1 1 CLASP N terminal AAA_5 PF07728.9 EIE82778.1 - 0.0086 15.8 0.1 5.6 6.6 0.0 3.8 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) DUF87 PF01935.12 EIE82778.1 - 0.012 15.4 5.2 0.61 9.8 0.0 4.0 6 0 0 6 6 4 0 Domain of unknown function DUF87 PRK PF00485.13 EIE82778.1 - 0.014 14.9 0.0 2.4 7.6 0.0 3.1 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family Viral_helicase1 PF01443.13 EIE82778.1 - 0.018 14.5 0.0 0.43 10.0 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase MutS_V PF00488.16 EIE82778.1 - 0.026 13.9 0.1 5.2 6.4 0.0 2.3 2 0 0 2 2 2 0 MutS domain V FtsK_SpoIIIE PF01580.13 EIE82778.1 - 0.092 12.2 0.1 24 4.3 0.0 3.1 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_13 PF13166.1 EIE82778.1 - 0.26 9.6 8.4 3.4 6.0 0.0 4.0 5 0 0 5 5 5 0 AAA domain zf-CCHC PF00098.18 EIE82779.1 - 1.3e-06 28.0 11.8 0.0035 17.1 0.2 2.4 2 0 0 2 2 2 2 Zinc knuckle zinc-ribbons_6 PF07191.7 EIE82779.1 - 0.00051 19.7 1.1 0.0024 17.6 0.4 2.0 2 0 0 2 2 2 1 zinc-ribbons zf-CCHC_4 PF14392.1 EIE82779.1 - 0.92 9.2 8.6 9.7 5.9 0.1 2.4 2 0 0 2 2 2 0 Zinc knuckle RVT_1 PF00078.22 EIE82780.1 - 1.8e-24 86.3 0.1 4e-24 85.1 0.0 1.6 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MRP-L27 PF09809.4 EIE82786.1 - 0.15 11.7 0.7 0.17 11.5 0.5 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L27 adh_short PF00106.20 EIE82787.1 - 2.3e-06 27.6 0.2 0.0053 16.6 0.1 2.6 2 1 0 2 2 2 2 short chain dehydrogenase KH_1 PF00013.24 EIE82789.1 - 4.4e-66 218.4 21.8 6.7e-11 41.6 0.5 9.4 9 0 0 9 9 9 8 KH domain KH_3 PF13014.1 EIE82789.1 - 1.4e-48 161.8 20.4 2.9e-09 36.3 0.0 9.3 9 0 0 9 9 9 7 KH domain KH_2 PF07650.12 EIE82789.1 - 1.1e-05 24.8 14.6 0.07 12.6 0.2 6.2 5 1 0 5 5 5 2 KH domain PhoPQ_related PF10142.4 EIE82789.1 - 0.035 12.5 1.2 0.61 8.5 0.0 2.7 2 1 0 3 3 3 0 PhoPQ-activated pathogenicity-related protein BMC PF00936.14 EIE82789.1 - 0.34 10.6 5.7 3.5 7.3 0.0 4.3 6 0 0 6 6 6 0 BMC domain DUF4458 PF14660.1 EIE82791.1 - 0.015 15.2 0.2 0.015 15.2 0.1 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4458) GPI-anchored PF10342.4 EIE82791.1 - 7.1 7.1 8.8 0.62 10.5 1.3 2.3 2 1 0 2 2 2 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF2812 PF11193.3 EIE82793.1 - 1.3 9.1 6.2 56 3.9 0.0 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2812) Ras PF00071.17 EIE82794.1 - 8.3e-58 194.3 0.1 9.8e-58 194.1 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIE82794.1 - 3e-20 72.8 0.1 6e-20 71.9 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EIE82794.1 - 6e-07 28.8 0.0 6.9e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EIE82794.1 - 8.8e-06 25.2 0.0 2e-05 24.0 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EIE82794.1 - 0.0037 17.1 0.0 0.0053 16.6 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Metallophos PF00149.23 EIE82795.1 - 9e-06 25.2 0.1 1.5e-05 24.5 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pkinase PF00069.20 EIE82796.1 - 8.9e-16 57.8 0.0 1.3e-09 37.6 0.1 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIE82796.1 - 8.1e-08 31.6 0.0 8.4e-05 21.7 0.1 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 EIE82796.1 - 0.0017 17.4 0.0 0.0024 16.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EIE82796.1 - 0.0089 15.0 0.3 1.2 8.0 0.1 2.1 2 0 0 2 2 2 2 Kinase-like UCH PF00443.24 EIE82797.1 - 4.6e-33 114.4 6.0 4.6e-33 114.4 4.2 2.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EIE82797.1 - 9.5e-12 44.9 1.0 9.5e-12 44.9 0.7 3.2 2 2 1 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase UQ_con PF00179.21 EIE82798.1 - 7.5e-16 57.8 0.0 8e-16 57.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EIE82798.1 - 0.013 15.3 0.0 0.015 15.1 0.0 1.2 1 0 0 1 1 1 0 RWD domain UEV PF05743.8 EIE82798.1 - 0.051 13.2 0.0 0.063 12.9 0.0 1.2 1 0 0 1 1 1 0 UEV domain IF4E PF01652.13 EIE82799.1 - 1.4e-56 190.5 0.7 1.7e-56 190.2 0.5 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E WD40 PF00400.27 EIE82800.1 - 1.6e-31 107.0 5.7 9.5e-09 34.8 0.1 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat Gmad1 PF10647.4 EIE82800.1 - 2.2e-05 23.9 0.2 3.5e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 Lipoprotein LpqB beta-propeller domain Cir_Bir_Yir PF06022.6 EIE82802.1 - 0.058 12.6 0.7 0.094 11.9 0.2 1.5 1 1 1 2 2 2 0 Plasmodium variant antigen protein Cir/Yir/Bir DDE_3 PF13358.1 EIE82803.1 - 6.6e-05 22.6 0.0 7.4e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 EIE82804.1 - 1.9e-10 40.8 0.0 3.1e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EIE82804.1 - 1.7e-08 33.8 0.1 2.6e-06 26.8 0.0 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.1 EIE82804.1 - 1.8e-08 34.2 0.0 1.5e-07 31.2 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_17 PF12728.2 EIE82804.1 - 4.9e-07 29.8 0.0 0.00025 21.2 0.0 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_32 PF13565.1 EIE82804.1 - 5.7e-05 23.8 0.0 0.00018 22.2 0.0 1.9 1 1 1 2 2 2 1 Homeodomain-like domain HTH_Tnp_1 PF01527.15 EIE82804.1 - 6.7e-05 22.7 0.0 0.00041 20.2 0.0 2.0 2 0 0 2 2 2 1 Transposase LZ_Tnp_IS481 PF13011.1 EIE82804.1 - 0.0015 18.8 0.0 0.011 16.0 0.0 2.0 2 0 0 2 2 2 1 leucine-zipper of insertion element IS481 Sigma70_r4_2 PF08281.7 EIE82804.1 - 0.0034 16.7 0.0 0.089 12.2 0.0 2.2 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_30 PF13556.1 EIE82804.1 - 0.0044 16.5 0.3 0.099 12.2 0.0 2.3 2 0 0 2 2 2 1 PucR C-terminal helix-turn-helix domain HTH_3 PF01381.17 EIE82804.1 - 0.007 16.1 0.0 4.5 7.1 0.0 2.3 2 0 0 2 2 2 2 Helix-turn-helix HTH_38 PF13936.1 EIE82804.1 - 0.017 14.6 0.1 0.21 11.1 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.1 EIE82804.1 - 0.018 14.1 0.1 0.095 11.8 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_Tnp_IS630 PF01710.11 EIE82804.1 - 0.019 14.6 0.2 5 6.8 0.0 2.4 1 1 1 2 2 2 0 Transposase HTH_36 PF13730.1 EIE82804.1 - 0.024 14.7 0.0 10 6.3 0.0 2.5 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.13 EIE82804.1 - 0.043 13.8 0.1 0.096 12.7 0.0 1.7 1 0 0 1 1 1 0 Transposase ANT PF03374.9 EIE82804.1 - 0.049 13.6 0.0 1.3 9.0 0.0 2.2 2 0 0 2 2 2 0 Phage antirepressor protein KilAC domain DUF3791 PF12668.2 EIE82804.1 - 0.065 12.8 0.0 0.24 11.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3791) HTH_8 PF02954.14 EIE82804.1 - 0.084 12.4 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family Kelch_5 PF13854.1 EIE82805.1 - 1.1e-15 57.1 0.2 4.2e-07 29.7 0.0 3.6 3 0 0 3 3 3 3 Kelch motif Kelch_3 PF13415.1 EIE82805.1 - 3.1e-14 52.6 10.8 9.3e-05 22.4 0.0 4.9 4 1 1 5 5 5 3 Galactose oxidase, central domain Kelch_4 PF13418.1 EIE82805.1 - 1.8e-12 46.8 8.3 3.8e-07 29.7 0.0 4.6 5 1 0 5 5 5 2 Galactose oxidase, central domain Kelch_6 PF13964.1 EIE82805.1 - 2.1e-09 37.1 7.8 0.00042 20.3 0.0 4.7 2 1 2 4 4 4 3 Kelch motif Kelch_2 PF07646.10 EIE82805.1 - 4.9e-06 26.0 3.7 0.021 14.5 0.0 4.2 4 1 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 EIE82805.1 - 0.019 14.5 7.1 0.19 11.2 0.0 3.5 4 0 0 4 4 4 0 Kelch motif RRM_1 PF00076.17 EIE82806.1 - 1.9e-19 69.0 0.1 2.7e-19 68.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE82806.1 - 2e-13 50.1 0.1 3.1e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE82806.1 - 5.3e-11 42.2 0.0 8.1e-11 41.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AMP-binding PF00501.23 EIE82807.1 - 2.3e-77 260.1 0.8 9.9e-75 251.4 0.5 2.2 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EIE82807.1 - 1.2e-16 61.3 0.9 9.6e-16 58.4 0.1 2.8 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain E1-E2_ATPase PF00122.15 EIE82808.1 - 2.6e-28 98.6 0.5 4.4e-28 97.8 0.3 1.4 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 EIE82808.1 - 6.5e-22 78.6 0.0 1.2e-21 77.7 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EIE82808.1 - 8.5e-16 59.0 0.0 4.1e-14 53.4 0.0 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EIE82808.1 - 4.5e-05 23.3 0.0 0.00014 21.7 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EIE82808.1 - 0.011 15.2 0.2 4.7 6.7 0.0 2.4 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase HSF_DNA-bind PF00447.12 EIE82809.1 - 5.2e-05 23.3 0.3 0.0016 18.5 0.2 2.5 1 1 0 1 1 1 1 HSF-type DNA-binding WD40 PF00400.27 EIE82810.1 - 2e-12 46.4 0.0 1.7e-06 27.6 0.0 3.3 3 0 0 3 3 3 3 WD domain, G-beta repeat CRT10 PF08728.5 EIE82810.1 - 4.8e-09 34.7 0.1 2.1e-08 32.6 0.0 1.8 1 1 0 1 1 1 1 CRT10 HA2 PF04408.18 EIE82811.1 - 9.1e-22 77.0 0.0 3.1e-21 75.2 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EIE82811.1 - 6.6e-15 54.9 0.0 6e-14 51.8 0.0 2.6 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EIE82811.1 - 2.4e-14 52.9 0.2 6.4e-14 51.5 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RWD PF05773.17 EIE82811.1 - 2.7e-12 46.5 0.7 8.2e-12 45.0 0.5 1.9 1 0 0 1 1 1 1 RWD domain DEAD PF00270.24 EIE82811.1 - 8.6e-08 31.8 0.3 2.2e-07 30.5 0.2 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase UBA PF00627.26 EIE82811.1 - 8.8e-08 31.7 0.0 0.00029 20.5 0.0 3.0 2 0 0 2 2 2 2 UBA/TS-N domain CHCH PF06747.8 EIE82811.1 - 2.7e-07 30.3 4.0 5.9e-07 29.2 2.8 1.6 1 0 0 1 1 1 1 CHCH domain AAA_22 PF13401.1 EIE82811.1 - 1.4e-05 25.2 1.7 5.2e-05 23.3 0.1 2.8 3 0 0 3 3 3 1 AAA domain DND1_DSRM PF14709.1 EIE82811.1 - 0.0011 19.2 0.2 0.005 17.0 0.1 2.2 1 1 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 T2SE PF00437.15 EIE82811.1 - 0.002 17.0 0.0 0.0051 15.7 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein Ecl1 PF12855.2 EIE82812.1 - 8.3e-10 37.7 4.1 1.4e-09 37.1 2.8 1.4 1 0 0 1 1 1 1 Life-span regulatory factor DUF329 PF03884.9 EIE82812.1 - 0.35 10.4 1.8 0.47 10.0 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF329) zf-MYND PF01753.13 EIE82812.1 - 0.83 9.5 3.4 0.41 10.5 0.6 1.8 2 0 0 2 2 2 0 MYND finger DEAD PF00270.24 EIE82813.1 - 6.2e-43 146.2 0.3 1e-42 145.4 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIE82813.1 - 7.3e-24 83.4 0.1 1.7e-23 82.2 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.1 EIE82813.1 - 0.0096 15.0 0.1 0.024 13.7 0.0 1.6 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit UvrD-helicase PF00580.16 EIE82813.1 - 0.04 13.2 1.6 0.12 11.6 0.0 2.0 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain LRR_9 PF14580.1 EIE82815.1 - 2.4e-61 206.3 2.7 2.6e-61 206.2 1.9 1.0 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.2 EIE82815.1 - 8e-10 38.1 16.9 0.00016 21.2 3.6 3.6 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EIE82815.1 - 1.8e-06 27.5 17.1 0.0012 18.5 2.5 2.9 3 1 0 3 3 3 2 Leucine rich repeat LON PF02190.11 EIE82816.1 - 8.7e-21 74.5 0.0 1.2e-20 74.0 0.0 1.2 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain zf-C3HC4_2 PF13923.1 EIE82816.1 - 0.00011 22.1 14.8 0.00011 22.1 10.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EIE82816.1 - 0.00015 21.5 12.0 0.00015 21.5 8.3 2.9 4 0 0 4 4 4 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EIE82816.1 - 0.00022 20.9 14.7 0.00022 20.9 10.2 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EIE82816.1 - 0.00061 19.4 11.3 0.00061 19.4 7.9 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIE82816.1 - 0.0029 17.2 14.9 0.0029 17.2 10.3 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIE82816.1 - 0.013 15.3 14.0 0.013 15.3 9.7 2.5 2 0 0 2 2 2 0 Ring finger domain zf-RING_UBOX PF13445.1 EIE82816.1 - 0.37 10.5 9.5 1.2 8.9 6.6 2.0 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_6 PF14835.1 EIE82816.1 - 5.9 6.7 11.3 3.4 7.5 5.9 2.0 2 0 0 2 2 2 0 zf-RING of BARD1-type protein XPG_I_2 PF12813.2 EIE82817.1 - 2.1e-17 63.4 0.0 3.9e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing XPG_N PF00752.12 EIE82817.1 - 4.8e-08 33.1 0.0 1e-07 32.1 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 EIE82817.1 - 0.033 14.2 0.0 0.067 13.2 0.0 1.6 1 0 0 1 1 1 0 XPG I-region Serinc PF03348.10 EIE82818.1 - 3.7e-116 388.3 23.9 2.2e-104 349.5 10.6 2.0 1 1 0 2 2 2 2 Serine incorporator (Serinc) MsyB PF13984.1 EIE82819.1 - 0.045 13.7 1.3 0.86 9.6 0.1 2.6 2 1 0 2 2 2 0 MsyB protein DUF1191 PF06697.7 EIE82819.1 - 0.12 11.1 0.0 0.26 10.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) HSP70 PF00012.15 EIE82820.1 - 1.4e-167 558.3 3.1 1.9e-167 557.8 2.1 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EIE82820.1 - 2.5e-12 46.0 0.4 1.9e-11 43.1 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein Thi4 PF01946.12 EIE82820.1 - 0.03 13.4 0.0 0.055 12.5 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Ketoacyl-synt_C PF02801.17 EIE82820.1 - 0.031 14.1 0.0 0.097 12.5 0.0 1.8 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain FtsA PF14450.1 EIE82820.1 - 0.14 11.9 4.8 11 5.8 0.5 3.5 2 1 0 2 2 2 0 Cell division protein FtsA CP2 PF04516.10 EIE82821.1 - 2.2e-54 184.0 0.2 3.3e-54 183.4 0.1 1.4 1 0 0 1 1 1 1 CP2 transcription factor DUF2207 PF09972.4 EIE82823.1 - 0.051 12.1 1.7 0.058 11.9 1.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Ribosomal_L28e PF01778.12 EIE82823.1 - 0.26 11.7 3.0 0.41 11.0 2.1 1.2 1 0 0 1 1 1 0 Ribosomal L28e protein family Sdh_cyt PF01127.17 EIE82823.1 - 9.6 6.0 12.5 0.062 13.1 3.0 1.6 2 0 0 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit GTP_EFTU PF00009.22 EIE82824.1 - 4.3e-54 182.8 0.1 7.2e-54 182.0 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EIE82824.1 - 7.4e-37 125.5 0.0 2.1e-36 124.1 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.1 EIE82824.1 - 3.7e-30 103.5 0.0 1e-29 102.2 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 EIE82824.1 - 1.3e-26 92.2 0.1 3.7e-26 90.8 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EIE82824.1 - 3e-11 43.2 0.2 1.1e-10 41.4 0.1 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 AIG1 PF04548.11 EIE82824.1 - 0.0057 15.7 0.1 0.011 14.8 0.0 1.4 1 0 0 1 1 1 1 AIG1 family FeoB_N PF02421.13 EIE82824.1 - 0.062 12.5 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B MMR_HSR1 PF01926.18 EIE82824.1 - 0.081 12.8 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase HTH_23 PF13384.1 EIE82825.1 - 0.0098 15.5 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.1 EIE82825.1 - 0.015 15.2 0.0 0.016 15.1 0.0 1.1 1 0 0 1 1 1 0 Helix-turn-helix domain DUF382 PF04037.8 EIE82827.1 - 0.12 12.1 0.2 0.71 9.7 0.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF382) FLO_LFY PF01698.11 EIE82827.1 - 1.6 7.5 7.8 1.8 7.3 5.4 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein ANTH PF07651.11 EIE82829.1 - 4.7e-23 81.2 3.1 6.2e-11 41.5 0.2 3.0 1 1 2 3 3 3 3 ANTH domain ENTH PF01417.15 EIE82829.1 - 1.1e-07 31.7 0.7 2.3e-07 30.6 0.3 1.7 2 0 0 2 2 2 1 ENTH domain YgaB PF14182.1 EIE82829.1 - 0.056 13.6 0.6 0.81 9.9 0.1 2.5 2 0 0 2 2 2 0 YgaB-like protein HLH PF00010.21 EIE82830.1 - 8e-14 51.0 0.6 8e-14 51.0 0.4 1.7 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Phi_1 PF04674.7 EIE82831.1 - 9.2e-29 100.4 1.1 1.4e-28 99.8 0.8 1.2 1 0 0 1 1 1 1 Phosphate-induced protein 1 conserved region DUF2129 PF09902.4 EIE82831.1 - 0.042 13.6 0.0 0.078 12.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2129) DUF1356 PF07092.7 EIE82832.1 - 0.021 13.9 0.1 0.045 12.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1356) DUF912 PF06024.7 EIE82832.1 - 0.023 14.7 3.7 0.9 9.6 0.0 3.0 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Sec62 PF03839.11 EIE82832.1 - 0.34 10.3 3.2 4.7 6.5 2.2 2.3 2 0 0 2 2 2 0 Translocation protein Sec62 CotH PF08757.6 EIE82833.1 - 1.7e-42 145.8 3.7 3e-42 145.0 2.5 1.4 1 0 0 1 1 1 1 CotH protein Arf PF00025.16 EIE82834.1 - 7.5e-50 168.5 2.8 1.8e-28 98.9 0.1 2.0 1 1 1 2 2 2 2 ADP-ribosylation factor family SRPRB PF09439.5 EIE82834.1 - 9e-07 28.2 1.1 0.00077 18.7 0.1 2.1 1 1 1 2 2 2 2 Signal recognition particle receptor beta subunit Ras PF00071.17 EIE82834.1 - 9.8e-06 25.0 0.2 0.061 12.7 0.1 2.0 1 1 1 2 2 2 2 Ras family MMR_HSR1 PF01926.18 EIE82834.1 - 0.00078 19.3 0.9 0.0017 18.3 0.6 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EIE82834.1 - 0.0014 19.1 0.4 0.017 15.6 0.3 2.0 1 1 0 1 1 1 1 Miro-like protein ABC_tran PF00005.22 EIE82834.1 - 0.0018 18.5 0.1 0.0026 18.0 0.1 1.2 1 0 0 1 1 1 1 ABC transporter AAA_14 PF13173.1 EIE82834.1 - 0.0055 16.5 0.2 0.011 15.5 0.2 1.5 1 1 0 1 1 1 1 AAA domain G-alpha PF00503.15 EIE82834.1 - 0.0088 14.7 0.8 0.67 8.5 0.0 2.0 1 1 1 2 2 2 2 G-protein alpha subunit GTP_EFTU PF00009.22 EIE82834.1 - 0.0099 15.3 0.3 2.4 7.5 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain cobW PF02492.14 EIE82834.1 - 0.024 14.0 2.3 1 8.7 0.1 2.1 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Pox_polyA_pol_C PF12629.2 EIE82834.1 - 0.071 12.8 0.3 0.098 12.3 0.2 1.2 1 0 0 1 1 1 0 Poxvirus poly(A) polymerase C-terminal domain G-7-MTase PF12803.2 EIE82834.1 - 0.072 12.2 0.0 0.08 12.0 0.0 1.1 1 0 0 1 1 1 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) Gtr1_RagA PF04670.7 EIE82834.1 - 0.076 12.1 0.3 0.12 11.4 0.2 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region FtsK_SpoIIIE PF01580.13 EIE82834.1 - 0.1 12.0 0.1 0.22 10.9 0.1 1.4 1 1 0 1 1 1 0 FtsK/SpoIIIE family 6PF2K PF01591.13 EIE82834.1 - 0.13 11.3 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase FeoB_N PF02421.13 EIE82834.1 - 0.26 10.5 2.3 2.2 7.5 0.1 2.1 1 1 1 2 2 2 0 Ferrous iron transport protein B E1-E2_ATPase PF00122.15 EIE82835.1 - 5.3e-17 61.6 5.9 3.4e-16 59.0 0.0 3.2 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 EIE82835.1 - 3.1e-14 52.7 0.0 2.4e-13 49.8 0.0 2.4 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase PF00702.21 EIE82835.1 - 7.2e-12 46.1 0.3 3.6e-10 40.6 0.2 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EIE82835.1 - 1.2e-11 45.1 0.3 5.4e-11 43.0 0.2 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EIE82835.1 - 0.00092 18.8 0.4 0.0064 16.0 0.1 2.5 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase PE PF00934.15 EIE82836.1 - 0.62 10.1 9.6 0.85 9.7 6.6 1.2 1 0 0 1 1 1 0 PE family ATC_hydrolase PF14196.1 EIE82836.1 - 3.8 7.9 5.5 4.4 7.7 3.8 1.1 1 0 0 1 1 1 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase Metaviral_G PF09595.5 EIE82836.1 - 6 6.4 8.9 7.4 6.1 6.2 1.1 1 0 0 1 1 1 0 Metaviral_G glycoprotein CENP-X PF09415.5 EIE82837.1 - 3.5e-14 52.3 0.6 4.2e-14 52.1 0.4 1.1 1 0 0 1 1 1 1 CENP-S associating Centromere protein X HMG_box PF00505.14 EIE82838.1 - 2.4e-14 53.3 0.8 2.4e-14 53.3 0.6 2.0 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EIE82838.1 - 1.3e-09 38.2 1.1 1.3e-09 38.2 0.7 1.9 2 0 0 2 2 2 1 HMG-box domain SAM_1 PF00536.25 EIE82838.1 - 0.00044 20.3 0.3 0.0011 19.1 0.0 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Fork_head PF00250.13 EIE82838.1 - 0.15 12.1 3.0 0.14 12.2 0.9 1.8 2 0 0 2 2 2 0 Fork head domain Ribosomal_S25 PF03297.10 EIE82839.1 - 9.1e-42 141.3 2.6 9.8e-42 141.2 1.8 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_24 PF13412.1 EIE82839.1 - 0.0068 15.7 0.5 0.01 15.2 0.3 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding BioT2 PF15368.1 EIE82839.1 - 0.025 14.3 0.3 0.027 14.2 0.2 1.2 1 0 0 1 1 1 0 Spermatogenesis family BioT2 MarR_2 PF12802.2 EIE82839.1 - 0.045 13.4 0.0 0.058 13.0 0.0 1.2 1 0 0 1 1 1 0 MarR family RNA_pol_Rpc34 PF05158.7 EIE82839.1 - 0.1 11.7 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase Rpc34 subunit BK_channel_a PF03493.13 EIE82840.1 - 1.5e-16 60.1 0.2 2.8e-10 40.0 0.0 3.5 2 1 1 3 3 3 3 Calcium-activated BK potassium channel alpha subunit TrkA_N PF02254.13 EIE82840.1 - 0.037 14.0 0.0 0.075 13.0 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Glyco_hydro_28 PF00295.12 EIE82843.1 - 7.5e-68 228.8 25.6 9.7e-68 228.5 17.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pkinase PF00069.20 EIE82845.1 - 5e-72 242.1 0.0 9.4e-72 241.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE82845.1 - 7.2e-49 166.1 0.0 1.3e-48 165.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 EIE82845.1 - 3.3e-21 75.4 0.0 3.3e-21 75.4 0.0 3.0 4 0 0 4 4 4 1 P21-Rho-binding domain Kinase-like PF14531.1 EIE82845.1 - 9.3e-07 28.0 0.0 1.6e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like DSHCT PF08148.7 EIE82845.1 - 0.007 15.6 0.1 0.017 14.3 0.0 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain APH PF01636.18 EIE82845.1 - 0.063 12.9 0.0 1.1 8.9 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Inhibitor_I10 PF12559.3 EIE82846.1 - 1.5 9.1 5.4 0.78 10.0 0.1 2.4 1 1 0 2 2 2 0 Serine endopeptidase inhibitors RVT_1 PF00078.22 EIE82847.1 - 6.3e-23 81.2 0.1 7.8e-23 80.9 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RhoGAP PF00620.22 EIE82848.1 - 5.2e-31 107.3 0.5 7.8e-31 106.7 0.3 1.3 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO_2 PF13716.1 EIE82848.1 - 2.1e-23 82.9 0.4 2.1e-23 82.9 0.3 1.9 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.15 EIE82848.1 - 0.00012 21.6 0.6 0.00061 19.3 0.1 2.3 3 0 0 3 3 3 1 CRAL/TRIO domain POC1 PF10450.4 EIE82848.1 - 0.02 13.6 0.1 0.054 12.2 0.0 1.7 1 1 1 2 2 2 0 POC1 chaperone MFS_1 PF07690.11 EIE82850.1 - 7.3e-24 84.1 37.5 1.4e-23 83.1 24.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIE82850.1 - 0.00014 20.5 10.8 0.00014 20.5 7.5 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter Flavi_NS4A PF01350.12 EIE82850.1 - 4.3 6.8 9.8 2.1 7.9 4.5 2.2 2 0 0 2 2 2 0 Flavivirus non-structural protein NS4A bZIP_1 PF00170.16 EIE82852.1 - 1.5e-08 34.4 11.9 2.8e-08 33.6 8.3 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EIE82852.1 - 2.7e-07 30.3 12.6 4.2e-07 29.6 8.8 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EIE82852.1 - 0.012 15.8 8.8 0.024 14.9 6.1 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor DivIC PF04977.10 EIE82852.1 - 0.72 9.3 3.5 1.3 8.5 2.4 1.5 1 0 0 1 1 1 0 Septum formation initiator tRNA-synt_2c PF01411.14 EIE82853.1 - 1.2e-211 703.8 0.0 1.7e-211 703.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 EIE82853.1 - 9.2e-19 67.0 0.6 2.1e-18 65.9 0.4 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 EIE82853.1 - 5.9e-09 35.4 1.8 1.7e-08 33.9 1.2 1.9 1 0 0 1 1 1 1 DHHA1 domain G10 PF01125.12 EIE82854.1 - 4.4e-59 198.2 1.8 6.1e-59 197.7 1.3 1.2 1 0 0 1 1 1 1 G10 protein Mito_carr PF00153.22 EIE82855.1 - 6.8e-52 173.1 7.3 1.5e-19 69.4 0.4 3.7 2 2 1 3 3 3 3 Mitochondrial carrier protein DUF771 PF05595.6 EIE82855.1 - 0.0063 16.4 0.5 1.1 9.2 0.1 2.4 1 1 0 2 2 2 2 Domain of unknown function (DUF771) MIP-T3 PF10243.4 EIE82856.1 - 3.4e-05 22.5 67.5 3.6e-05 22.4 46.8 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Daxx PF03344.10 EIE82856.1 - 0.0023 16.5 40.7 0.0028 16.2 28.2 1.0 1 0 0 1 1 1 1 Daxx Family Utp14 PF04615.8 EIE82856.1 - 0.01 14.0 54.5 0.011 13.8 37.8 1.0 1 0 0 1 1 1 0 Utp14 protein PAP2 PF01569.16 EIE82856.1 - 0.054 13.1 0.0 0.063 12.9 0.0 1.1 1 0 0 1 1 1 0 PAP2 superfamily PLRV_ORF5 PF01690.12 EIE82856.1 - 1.3 8.0 32.9 1.5 7.9 22.8 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Mitofilin PF09731.4 EIE82856.1 - 2.5 6.6 45.1 2.9 6.4 31.3 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein LMBR1 PF04791.11 EIE82856.1 - 3.5 6.1 17.4 3.8 5.9 12.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein CDC45 PF02724.9 EIE82856.1 - 6.4 4.6 46.6 9.5 4.1 32.3 1.2 1 0 0 1 1 1 0 CDC45-like protein ParBc PF02195.13 EIE82857.1 - 4.2e-12 45.9 0.0 5.3e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 ParB-like nuclease domain Lipase_GDSL_2 PF13472.1 EIE82858.1 - 1e-06 29.0 0.0 1.4e-06 28.5 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EIE82858.1 - 2.3e-05 24.3 0.0 3.2e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase ACOX PF01756.14 EIE82859.1 - 7.5e-31 106.9 0.0 2.2e-30 105.4 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 EIE82859.1 - 9.4e-16 58.2 0.4 9.4e-16 58.2 0.3 1.9 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 EIE82859.1 - 2.4e-11 42.9 0.9 4.6e-11 42.0 0.7 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain LAM_C PF12544.3 EIE82859.1 - 0.11 12.6 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 Lysine-2,3-aminomutase Lactate_perm PF02652.9 EIE82860.1 - 2e-91 307.0 20.5 2.2e-89 300.3 14.2 2.0 1 1 0 1 1 1 1 L-lactate permease DUF4199 PF13858.1 EIE82860.1 - 1.2 9.0 18.1 1.3 8.8 2.6 4.0 4 1 1 5 5 5 0 Protein of unknown function (DUF4199) zf-CCHC PF00098.18 EIE82861.1 - 6e-07 29.0 9.7 0.00014 21.5 0.6 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 EIE82861.1 - 0.00075 19.1 2.9 0.15 11.7 0.2 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.1 EIE82861.1 - 0.0099 15.3 4.6 0.016 14.7 0.7 2.3 1 1 1 2 2 2 1 Zinc knuckle zf-CCHC_6 PF15288.1 EIE82861.1 - 0.017 14.7 8.9 0.14 11.8 1.0 2.7 1 1 1 2 2 2 0 Zinc knuckle Cmc1 PF08583.5 EIE82861.1 - 0.62 9.8 3.4 1.1 9.0 2.4 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like RVT_1 PF00078.22 EIE82862.1 - 4e-34 117.8 0.1 4.7e-33 114.3 0.0 2.3 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1212 PF06738.7 EIE82863.1 - 0.059 12.8 0.7 0.075 12.4 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1212) Imm8 PF15560.1 EIE82865.1 - 0.16 11.6 0.9 6 6.5 0.2 2.0 1 1 1 2 2 2 0 Immunity protein 8 Hist_deacetyl PF00850.14 EIE82866.1 - 2.9e-64 217.3 0.0 3.6e-64 217.0 0.0 1.0 1 0 0 1 1 1 1 Histone deacetylase domain Cu-oxidase_2 PF07731.9 EIE82867.1 - 1.1e-12 47.5 3.9 1.4e-10 40.7 2.7 2.1 1 1 0 1 1 1 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 EIE82867.1 - 5.7e-05 22.8 1.0 0.00019 21.1 0.7 1.8 1 1 0 1 1 1 1 Multicopper oxidase CTP_transf_2 PF01467.21 EIE82868.1 - 9.8e-23 80.9 0.0 1.2e-22 80.6 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase DUF1237 PF06824.6 EIE82869.1 - 7.3e-106 354.2 0.4 2.6e-72 243.7 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF1237) DEAD PF00270.24 EIE82870.1 - 9.8e-46 155.3 0.2 3.3e-45 153.6 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIE82870.1 - 1.7e-21 75.8 0.0 4e-21 74.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EIE82870.1 - 2.5e-20 71.7 0.4 4.8e-20 70.8 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Daxx PF03344.10 EIE82870.1 - 0.076 11.5 22.9 0.13 10.6 15.8 1.3 1 0 0 1 1 1 0 Daxx Family DUF1908 PF08926.6 EIE82871.1 - 0.057 12.1 0.1 0.063 12.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1908) L27_N PF09060.5 EIE82871.1 - 0.083 12.7 1.0 0.3 10.9 0.0 2.2 3 0 0 3 3 3 0 L27_N DDE_3 PF13358.1 EIE82872.1 - 5.2e-14 52.2 0.3 7.3e-14 51.7 0.2 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Racemase_4 PF13615.1 EIE82873.1 - 1.1e-18 67.3 0.3 2.5e-18 66.2 0.2 1.6 1 0 0 1 1 1 1 Putative alanine racemase MCM_bind PF09739.4 EIE82873.1 - 2.1e-12 46.6 0.1 5.8e-12 45.2 0.1 1.8 1 0 0 1 1 1 1 Mini-chromosome maintenance replisome factor MCM PF00493.18 EIE82873.1 - 0.0084 14.9 1.2 0.023 13.5 0.1 2.1 3 0 0 3 3 3 1 MCM2/3/5 family Pkinase PF00069.20 EIE82874.1 - 5.6e-68 228.8 0.0 6.8e-68 228.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE82874.1 - 3.9e-47 160.5 0.0 5.5e-47 160.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE82874.1 - 8.9e-06 24.8 0.0 1.3e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EIE82874.1 - 0.0058 16.3 0.0 0.037 13.7 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EIE82874.1 - 0.018 14.1 0.2 0.05 12.6 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 EIE82874.1 - 0.02 13.7 0.2 0.031 13.0 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 PBD PF00786.23 EIE82874.1 - 0.023 15.0 0.1 0.052 13.9 0.0 1.6 1 0 0 1 1 1 0 P21-Rho-binding domain DUF2764 PF10962.3 EIE82874.1 - 0.098 11.8 0.0 0.21 10.8 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2764) HTH_Tnp_Tc3_2 PF01498.13 EIE82875.1 - 6.4e-09 35.7 2.6 8.4e-09 35.3 1.8 1.2 1 0 0 1 1 1 1 Transposase DUF273 PF03314.9 EIE82875.1 - 0.035 13.4 0.1 0.036 13.3 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function, DUF273 Ricin_B_lectin PF00652.17 EIE82876.1 - 0.00053 20.0 4.0 0.0094 15.9 2.4 2.4 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 EIE82876.1 - 0.0091 16.3 3.1 0.36 11.2 1.1 2.1 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like PPO1_DWL PF12142.3 EIE82876.1 - 0.055 12.9 0.6 0.11 12.0 0.4 1.4 1 0 0 1 1 1 0 Polyphenol oxidase middle domain CotH PF08757.6 EIE82877.1 - 4.5e-40 137.8 0.4 7.8e-40 137.0 0.2 1.3 1 0 0 1 1 1 1 CotH protein UPF0158 PF03682.8 EIE82877.1 - 0.026 14.1 0.2 5.3 6.6 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0158) DUF1308 PF07000.6 EIE82878.1 - 4e-40 137.5 0.0 6e-40 136.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1308) RELT PF12606.3 EIE82878.1 - 0.11 11.6 0.5 0.3 10.2 0.4 1.7 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 Aa_trans PF01490.13 EIE82880.1 - 2.2e-64 217.4 25.3 2.5e-64 217.2 17.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2975 PF11188.3 EIE82881.1 - 0.12 12.0 3.9 0.063 12.9 1.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2975) FA_hydroxylase PF04116.8 EIE82882.1 - 6.3e-15 55.5 21.8 6.3e-15 55.5 15.1 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DASH_Ask1 PF08655.5 EIE82882.1 - 0.046 13.5 0.2 0.52 10.1 0.1 2.3 2 0 0 2 2 2 0 DASH complex subunit Ask1 DUF4146 PF13652.1 EIE82883.1 - 0.023 14.4 0.2 0.032 14.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4146) HTH_21 PF13276.1 EIE82883.1 - 0.53 10.3 4.1 8.4 6.4 0.3 2.3 2 0 0 2 2 2 0 HTH-like domain Y_phosphatase PF00102.22 EIE82884.1 - 1.6e-25 89.8 0.5 5.7e-25 88.0 0.0 2.1 2 1 0 2 2 2 1 Protein-tyrosine phosphatase Rhodanese PF00581.15 EIE82884.1 - 1.8e-11 44.3 0.0 3.9e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain DUF2404 PF10296.4 EIE82885.1 - 4.2e-06 26.8 0.1 0.0001 22.3 0.0 2.4 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) NmrA PF05368.8 EIE82886.1 - 2.2e-10 40.2 0.5 2.9e-10 39.7 0.4 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EIE82886.1 - 2.3e-07 31.0 0.0 5.4e-07 29.7 0.0 1.5 2 0 0 2 2 2 1 NADH(P)-binding Glutaredoxin PF00462.19 EIE82886.1 - 0.073 13.0 0.4 4.7 7.2 0.1 2.8 2 0 0 2 2 2 0 Glutaredoxin RmlD_sub_bind PF04321.12 EIE82886.1 - 0.11 11.3 0.1 0.7 8.7 0.0 2.0 2 0 0 2 2 2 0 RmlD substrate binding domain ORF6N PF10543.4 EIE82886.1 - 0.55 10.3 6.8 1.8 8.6 0.1 3.7 3 1 1 4 4 4 0 ORF6N domain Ribosomal_S8 PF00410.14 EIE82887.1 - 8.2e-21 74.1 0.0 1e-20 73.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 MCPsignal PF00015.16 EIE82889.1 - 6.6e-05 22.5 23.3 0.00019 21.0 16.1 1.6 1 1 0 1 1 1 1 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF948 PF06103.6 EIE82889.1 - 7.8e-05 22.4 30.4 0.0027 17.5 14.0 2.1 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF948) Prominin PF05478.6 EIE82889.1 - 0.00013 19.6 17.3 0.00018 19.1 12.0 1.2 1 0 0 1 1 1 1 Prominin TMPIT PF07851.8 EIE82889.1 - 0.0002 20.5 16.2 0.00024 20.2 11.3 1.1 1 0 0 1 1 1 1 TMPIT-like protein Acyl-CoA_dh_C PF12806.2 EIE82889.1 - 0.00022 21.0 5.9 0.0081 16.0 0.9 2.2 1 1 1 2 2 2 2 Acetyl-CoA dehydrogenase C-terminal like Sigma70_ner PF04546.8 EIE82889.1 - 0.00032 20.3 22.4 0.017 14.7 6.9 2.1 1 1 1 2 2 2 2 Sigma-70, non-essential region HisKA_3 PF07730.8 EIE82889.1 - 0.00038 20.7 5.1 1.4 9.2 3.5 3.0 1 1 0 1 1 1 0 Histidine kinase UPF0118 PF01594.11 EIE82889.1 - 0.00043 19.3 7.8 0.0005 19.1 3.2 2.0 1 1 1 2 2 2 1 Domain of unknown function DUF20 DASH_Duo1 PF08651.5 EIE82889.1 - 0.00045 19.7 15.2 0.08 12.5 4.8 2.6 1 1 2 3 3 3 3 DASH complex subunit Duo1 Fib_alpha PF08702.5 EIE82889.1 - 0.00055 20.0 23.7 0.0095 16.0 16.5 2.0 1 1 0 1 1 1 1 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.7 EIE82889.1 - 0.00063 19.5 11.1 0.0059 16.4 7.7 1.9 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus TMP_2 PF06791.8 EIE82889.1 - 0.00066 19.3 10.4 0.00081 19.0 7.2 1.2 1 0 0 1 1 1 1 Prophage tail length tape measure protein ISG65-75 PF11727.3 EIE82889.1 - 0.0007 18.7 16.6 0.00083 18.5 11.5 1.1 1 0 0 1 1 1 1 Invariant surface glycoprotein APG6 PF04111.7 EIE82889.1 - 0.00071 18.7 8.9 0.00081 18.5 6.2 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 AAA_13 PF13166.1 EIE82889.1 - 0.00085 17.9 12.4 0.001 17.6 8.6 1.0 1 0 0 1 1 1 1 AAA domain Dor1 PF04124.7 EIE82889.1 - 0.00089 17.8 3.0 0.0012 17.3 2.1 1.2 1 0 0 1 1 1 1 Dor1-like family Laminin_II PF06009.7 EIE82889.1 - 0.001 18.8 25.3 0.0032 17.2 17.6 1.7 1 1 0 1 1 1 1 Laminin Domain II Herpes_UL92 PF03048.9 EIE82889.1 - 0.001 18.6 15.8 0.0012 18.5 10.9 1.0 1 0 0 1 1 1 1 UL92 family EzrA PF06160.7 EIE82889.1 - 0.0011 17.2 17.8 0.0014 16.9 12.3 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Myosin_tail_1 PF01576.14 EIE82889.1 - 0.0011 16.7 12.2 0.0014 16.5 8.4 1.0 1 0 0 1 1 1 1 Myosin tail RmuC PF02646.11 EIE82889.1 - 0.0014 17.5 23.6 0.0058 15.5 12.3 2.0 1 1 1 2 2 2 1 RmuC family Reo_sigmaC PF04582.7 EIE82889.1 - 0.0014 17.8 3.7 0.0018 17.4 2.6 1.2 1 0 0 1 1 1 1 Reovirus sigma C capsid protein Herpes_U30 PF04523.8 EIE82889.1 - 0.0018 15.8 5.9 0.002 15.6 4.1 1.0 1 0 0 1 1 1 1 Herpes virus tegument protein U30 phiKZ_IP PF12699.2 EIE82889.1 - 0.0019 17.1 18.5 0.024 13.5 6.1 2.1 1 1 1 2 2 2 2 phiKZ-like phage internal head proteins Tape_meas_lam_C PF09718.5 EIE82889.1 - 0.0021 17.9 0.5 0.21 11.5 0.4 2.8 1 1 0 1 1 1 1 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Laminin_I PF06008.9 EIE82889.1 - 0.0021 17.4 18.5 0.0056 16.0 12.8 1.8 1 1 0 1 1 1 1 Laminin Domain I BLOC1_2 PF10046.4 EIE82889.1 - 0.0022 18.1 19.5 0.028 14.5 13.5 2.2 1 1 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF745 PF05335.8 EIE82889.1 - 0.0026 17.3 25.2 0.0034 16.9 17.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF745) DUF2203 PF09969.4 EIE82889.1 - 0.0028 17.8 17.2 0.0068 16.6 7.6 2.0 1 1 1 2 2 2 1 Uncharacterized conserved protein (DUF2203) GAS PF13851.1 EIE82889.1 - 0.003 16.8 19.1 0.0035 16.5 13.3 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding DUF3829 PF12889.2 EIE82889.1 - 0.0031 16.7 11.8 0.0091 15.2 8.2 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3829) Syntaxin PF00804.20 EIE82889.1 - 0.0032 17.6 15.6 0.0065 16.6 10.8 1.5 1 1 0 1 1 1 1 Syntaxin DHC_N2 PF08393.8 EIE82889.1 - 0.0033 16.0 23.0 0.016 13.6 14.9 1.9 1 1 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 Glutaredoxin2_C PF04399.8 EIE82889.1 - 0.0036 16.8 4.2 0.15 11.6 1.3 2.5 1 1 0 1 1 1 1 Glutaredoxin 2, C terminal domain Vps53_N PF04100.7 EIE82889.1 - 0.0038 16.0 17.0 0.0048 15.7 11.8 1.1 1 0 0 1 1 1 1 Vps53-like, N-terminal ScpA_ScpB PF02616.9 EIE82889.1 - 0.004 16.7 18.6 0.0048 16.5 12.9 1.1 1 0 0 1 1 1 1 ScpA/B protein IFT57 PF10498.4 EIE82889.1 - 0.0044 15.8 22.6 0.0053 15.5 15.7 1.1 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 DUF2935 PF11155.3 EIE82889.1 - 0.0045 17.0 13.2 0.13 12.3 9.1 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF2935) Spc7 PF08317.6 EIE82889.1 - 0.005 15.5 16.5 0.0063 15.2 11.4 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Mnd1 PF03962.10 EIE82889.1 - 0.0054 16.4 15.7 0.0067 16.1 10.9 1.0 1 0 0 1 1 1 1 Mnd1 family MutS_III PF05192.13 EIE82889.1 - 0.0056 16.4 1.0 0.0067 16.2 0.7 1.0 1 0 0 1 1 1 1 MutS domain III DUF972 PF06156.8 EIE82889.1 - 0.0068 16.7 20.0 1.7 9.0 13.9 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Tweety PF04906.8 EIE82889.1 - 0.0068 14.8 16.1 0.009 14.4 11.1 1.2 1 0 0 1 1 1 1 Tweety AAA_27 PF13514.1 EIE82889.1 - 0.007 14.1 7.2 0.0079 13.9 5.0 1.0 1 0 0 1 1 1 1 AAA domain Med4 PF10018.4 EIE82889.1 - 0.0072 15.7 13.5 0.04 13.3 9.4 1.9 1 1 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 PPE PF00823.14 EIE82889.1 - 0.0076 16.0 0.1 0.011 15.6 0.1 1.2 1 0 0 1 1 1 1 PPE family Syntaxin_2 PF14523.1 EIE82889.1 - 0.0088 16.0 20.3 0.02 14.9 14.1 1.6 1 1 0 1 1 1 1 Syntaxin-like protein FH2 PF02181.18 EIE82889.1 - 0.0098 14.8 19.3 0.018 13.9 13.4 1.4 1 1 0 1 1 1 1 Formin Homology 2 Domain V-SNARE PF05008.10 EIE82889.1 - 0.012 15.7 15.9 1.2 9.3 11.1 2.3 1 1 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus PhageMin_Tail PF10145.4 EIE82889.1 - 0.012 15.2 4.3 0.017 14.7 3.0 1.2 1 0 0 1 1 1 0 Phage-related minor tail protein DUF677 PF05055.7 EIE82889.1 - 0.013 14.2 24.3 0.015 14.0 16.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF677) DUF1351 PF07083.6 EIE82889.1 - 0.013 15.1 17.1 0.019 14.5 11.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1351) ALIX_LYPXL_bnd PF13949.1 EIE82889.1 - 0.013 14.4 15.6 0.021 13.7 10.8 1.4 1 1 0 1 1 1 0 ALIX V-shaped domain binding to HIV DHC_N1 PF08385.7 EIE82889.1 - 0.013 13.8 12.5 0.017 13.5 8.7 1.2 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 1 FlgN PF05130.7 EIE82889.1 - 0.014 15.6 4.4 0.033 14.4 3.1 1.7 1 1 0 1 1 1 0 FlgN protein ApoO PF09769.4 EIE82889.1 - 0.014 15.1 14.8 0.046 13.4 5.7 2.0 1 1 1 2 2 2 0 Apolipoprotein O DUF883 PF05957.8 EIE82889.1 - 0.018 15.3 13.3 0.072 13.4 6.1 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DASH_Dad3 PF08656.5 EIE82889.1 - 0.019 14.6 9.3 17 5.1 6.4 2.4 1 1 0 1 1 1 0 DASH complex subunit Dad3 YlqD PF11068.3 EIE82889.1 - 0.021 14.8 32.8 2.4 8.1 22.8 2.0 1 1 0 1 1 1 0 YlqD protein NAAA-beta PF15508.1 EIE82889.1 - 0.021 15.1 16.1 2e+02 2.4 11.1 2.7 1 1 0 1 1 1 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase DivIVA PF05103.8 EIE82889.1 - 0.022 14.8 19.1 0.029 14.4 13.2 1.1 1 0 0 1 1 1 0 DivIVA protein AF0941-like PF14591.1 EIE82889.1 - 0.027 14.5 16.5 0.05 13.6 11.4 1.5 1 1 0 1 1 1 0 AF0941-like YkyA PF10368.4 EIE82889.1 - 0.028 13.7 22.0 0.078 12.3 15.3 1.6 1 1 0 1 1 1 0 Putative cell-wall binding lipoprotein DUF869 PF05911.6 EIE82889.1 - 0.028 12.6 17.3 0.034 12.4 12.0 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) WXG100 PF06013.7 EIE82889.1 - 0.031 14.2 14.0 26 4.8 9.7 3.1 1 1 0 1 1 1 0 Proteins of 100 residues with WXG Adenylsucc_synt PF00709.16 EIE82889.1 - 0.032 12.9 10.7 0.044 12.4 7.4 1.2 1 0 0 1 1 1 0 Adenylosuccinate synthetase DUF746 PF05344.6 EIE82889.1 - 0.032 13.7 7.9 2.3 7.8 0.4 3.3 1 1 2 3 3 3 0 Domain of Unknown Function (DUF746) BMFP PF04380.8 EIE82889.1 - 0.032 14.3 18.3 0.36 10.9 3.0 3.0 1 1 2 3 3 3 0 Membrane fusogenic activity Peptidase_C6 PF00851.13 EIE82889.1 - 0.033 12.8 14.7 0.039 12.5 10.2 1.0 1 0 0 1 1 1 0 Helper component proteinase FliD_C PF07195.7 EIE82889.1 - 0.033 13.4 11.5 0.038 13.2 8.0 1.0 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus zf-C4H2 PF10146.4 EIE82889.1 - 0.035 14.1 10.8 0.038 13.9 7.5 1.0 1 0 0 1 1 1 0 Zinc finger-containing protein DUF1664 PF07889.7 EIE82889.1 - 0.037 13.8 26.1 0.58 9.9 18.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) SPOB_a PF14689.1 EIE82889.1 - 0.039 13.5 21.5 4.1 7.0 1.0 4.2 1 1 1 2 2 1 0 Sensor_kinase_SpoOB-type, alpha-helical domain Phage_GP20 PF06810.6 EIE82889.1 - 0.04 13.3 23.3 0.4 10.1 5.9 2.0 1 1 1 2 2 2 0 Phage minor structural protein GP20 Seryl_tRNA_N PF02403.17 EIE82889.1 - 0.041 13.9 19.7 0.11 12.4 13.6 1.6 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF2400 PF09674.5 EIE82889.1 - 0.044 13.4 7.1 0.064 12.9 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) CorA PF01544.13 EIE82889.1 - 0.046 12.7 0.3 0.053 12.5 0.2 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein HAUS-augmin3 PF14932.1 EIE82889.1 - 0.049 12.8 14.9 0.059 12.5 10.4 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Dak2 PF02734.12 EIE82889.1 - 0.05 13.2 8.0 0.068 12.8 5.6 1.2 1 0 0 1 1 1 0 DAK2 domain DUF3540 PF12059.3 EIE82889.1 - 0.052 13.1 24.2 0.19 11.3 8.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3540) Peptidase_M9_N PF08453.5 EIE82889.1 - 0.053 12.8 10.7 1.1 8.5 0.3 2.0 1 1 1 2 2 2 0 Peptidase family M9 N-terminal YjcZ PF13990.1 EIE82889.1 - 0.058 12.5 12.2 0.094 11.8 8.5 1.3 1 0 0 1 1 1 0 YjcZ-like protein PhoU_div PF01865.11 EIE82889.1 - 0.059 12.5 13.7 0.26 10.4 9.5 1.9 1 1 0 1 1 1 0 Protein of unknown function DUF47 DUF2317 PF10079.4 EIE82889.1 - 0.062 11.9 14.9 0.068 11.7 10.3 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) Ferritin PF00210.19 EIE82889.1 - 0.066 12.9 6.0 2.8 7.6 4.2 2.1 1 1 0 1 1 1 0 Ferritin-like domain EST1_DNA_bind PF10373.4 EIE82889.1 - 0.068 12.3 0.5 0.077 12.1 0.3 1.1 1 0 0 1 1 1 0 Est1 DNA/RNA binding domain Allexi_40kDa PF05549.6 EIE82889.1 - 0.079 12.2 8.8 0.097 11.9 6.1 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein IncA PF04156.9 EIE82889.1 - 0.082 12.4 9.3 0.11 12.0 6.4 1.2 1 0 0 1 1 1 0 IncA protein AIP3 PF03915.8 EIE82889.1 - 0.082 11.7 18.5 0.12 11.2 12.9 1.3 1 0 0 1 1 1 0 Actin interacting protein 3 COG5 PF10392.4 EIE82889.1 - 0.099 12.6 12.8 0.27 11.2 8.8 1.7 1 1 0 1 1 1 0 Golgi transport complex subunit 5 CHASE3 PF05227.8 EIE82889.1 - 0.1 12.2 10.0 0.18 11.4 6.9 1.4 1 1 0 1 1 1 0 CHASE3 domain Borrelia_lipo_1 PF05714.6 EIE82889.1 - 0.1 11.6 8.7 0.15 11.1 6.1 1.2 1 0 0 1 1 1 0 Borrelia burgdorferi virulent strain associated lipoprotein DUF1395 PF07160.7 EIE82889.1 - 0.11 11.9 16.1 0.16 11.4 11.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1395) Filament PF00038.16 EIE82889.1 - 0.11 11.9 14.4 0.14 11.6 10.0 1.0 1 0 0 1 1 1 0 Intermediate filament protein APG17 PF04108.7 EIE82889.1 - 0.11 11.2 19.0 0.29 9.8 13.2 1.6 1 1 0 1 1 1 0 Autophagy protein Apg17 DUF816 PF05674.7 EIE82889.1 - 0.12 12.1 13.3 0.16 11.6 9.3 1.1 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF816) DUF2130 PF09903.4 EIE82889.1 - 0.12 11.0 15.3 0.19 10.4 10.6 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2130) Syntaxin-6_N PF09177.6 EIE82889.1 - 0.13 12.7 13.6 0.19 12.1 9.4 1.3 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Spectrin PF00435.16 EIE82889.1 - 0.13 12.5 15.6 0.3 11.3 10.8 1.6 1 1 0 1 1 1 0 Spectrin repeat DUF935 PF06074.7 EIE82889.1 - 0.13 10.9 2.8 0.33 9.6 1.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF935) ALMT PF11744.3 EIE82889.1 - 0.13 10.8 15.7 0.2 10.2 10.9 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF3450 PF11932.3 EIE82889.1 - 0.14 11.3 23.9 0.19 10.9 16.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Flagellin_N PF00669.15 EIE82889.1 - 0.15 11.8 5.4 0.2 11.4 3.7 1.2 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region Lipoprotein_7 PF01540.11 EIE82889.1 - 0.17 10.9 11.5 0.21 10.6 8.0 1.1 1 0 0 1 1 1 0 Adhesin lipoprotein MitMem_reg PF13012.1 EIE82889.1 - 0.18 11.9 16.5 2.2 8.4 11.5 2.0 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function HD_5 PF13487.1 EIE82889.1 - 0.18 11.8 2.7 11 6.1 0.8 2.8 1 1 1 2 2 2 0 HD domain PMEI PF04043.10 EIE82889.1 - 0.19 11.6 1.1 0.49 10.2 0.8 1.7 1 1 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor COG2 PF06148.6 EIE82889.1 - 0.19 11.5 26.3 38 4.1 18.2 2.5 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF479 PF04336.7 EIE82889.1 - 0.21 11.7 6.4 6.8 6.8 4.4 2.4 1 1 0 1 1 1 0 Protein of unknown function, DUF479 Strumpellin PF10266.4 EIE82889.1 - 0.21 8.9 16.7 0.27 8.5 11.6 1.2 1 0 0 1 1 1 0 Hereditary spastic paraplegia protein strumpellin Hpt PF01627.18 EIE82889.1 - 0.25 11.3 0.9 4.7 7.2 0.6 2.4 1 1 0 1 1 1 0 Hpt domain TerB PF05099.8 EIE82889.1 - 0.25 11.0 4.9 2.3 7.9 0.5 2.1 1 1 1 2 2 2 0 Tellurite resistance protein TerB SEN1_N PF12726.2 EIE82889.1 - 0.25 9.3 4.4 0.31 9.0 3.1 1.1 1 0 0 1 1 1 0 SEN1 N terminal Acetyltransf_11 PF13720.1 EIE82889.1 - 0.26 11.5 6.4 20 5.4 4.4 2.4 1 1 0 1 1 1 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 TMF_DNA_bd PF12329.3 EIE82889.1 - 0.26 11.0 18.0 1.6 8.6 3.1 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding V_ATPase_I PF01496.14 EIE82889.1 - 0.26 9.0 18.4 0.31 8.8 12.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TipAS PF07739.8 EIE82889.1 - 0.27 11.5 10.2 0.66 10.3 7.1 1.7 1 1 0 1 1 1 0 TipAS antibiotic-recognition domain Atg14 PF10186.4 EIE82889.1 - 0.27 10.1 16.7 0.31 9.9 11.6 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 PLU-1 PF08429.6 EIE82889.1 - 0.28 10.0 16.0 0.52 9.1 11.1 1.4 1 1 0 1 1 1 0 PLU-1-like protein CK2S PF15011.1 EIE82889.1 - 0.29 10.9 23.5 3.8e+02 0.7 16.3 2.8 1 1 0 1 1 1 0 Casein Kinase 2 substrate Trehalase PF01204.13 EIE82889.1 - 0.29 9.7 11.0 0.35 9.4 7.6 1.1 1 0 0 1 1 1 0 Trehalase DUF3508 PF12018.3 EIE82889.1 - 0.31 9.9 14.9 0.38 9.7 10.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3508) DUF19 PF01579.13 EIE82889.1 - 0.31 10.9 9.0 2.4 8.1 6.2 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF19) IFT46_B_C PF12317.3 EIE82889.1 - 0.32 10.3 10.7 0.45 9.8 7.4 1.3 1 0 0 1 1 1 0 Intraflagellar transport complex B protein 46 C terminal DUF3584 PF12128.3 EIE82889.1 - 0.32 8.2 21.3 0.35 8.1 14.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Sec34 PF04136.10 EIE82889.1 - 0.32 10.6 8.9 0.8 9.3 6.2 1.7 1 1 0 1 1 1 0 Sec34-like family DUF2383 PF09537.5 EIE82889.1 - 0.34 11.1 3.7 0.56 10.4 2.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF2383) CAP_N PF01213.14 EIE82889.1 - 0.34 10.1 13.7 0.43 9.8 9.5 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal TMCO5 PF14992.1 EIE82889.1 - 0.34 9.9 18.3 0.37 9.8 12.7 1.0 1 0 0 1 1 1 0 TMCO5 family DUF2232 PF09991.4 EIE82889.1 - 0.35 9.8 21.4 6.7e+02 -1.0 14.9 2.3 1 1 0 1 1 0 0 Predicted membrane protein (DUF2232) PHA_synth_III_E PF09712.5 EIE82889.1 - 0.37 10.1 10.8 0.73 9.1 7.5 1.5 1 1 0 1 1 1 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) LXG PF04740.7 EIE82889.1 - 0.37 10.5 19.3 6 6.6 9.5 2.7 1 1 1 2 2 2 0 LXG domain of WXG superfamily Vac_Fusion PF02346.11 EIE82889.1 - 0.38 10.2 15.9 20 4.6 3.1 3.5 1 1 1 2 2 2 0 Chordopoxvirus fusion protein Peptidase_S64 PF08192.6 EIE82889.1 - 0.38 9.0 11.8 0.45 8.7 8.2 1.1 1 0 0 1 1 1 0 Peptidase family S64 DUF4404 PF14357.1 EIE82889.1 - 0.39 11.1 5.2 1.3 9.4 3.6 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4404) Peptidase_M75 PF09375.5 EIE82889.1 - 0.4 9.9 6.3 5.9 6.1 4.4 2.1 1 1 0 1 1 1 0 Imelysin CDC37_N PF03234.9 EIE82889.1 - 0.4 10.9 15.6 0.54 10.5 10.8 1.1 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding BicD PF09730.4 EIE82889.1 - 0.41 8.9 15.8 0.53 8.5 11.0 1.2 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D Peptidase_C65 PF10275.4 EIE82889.1 - 0.43 9.9 14.0 5.2 6.3 9.7 1.9 1 1 0 1 1 1 0 Peptidase C65 Otubain AKNA PF12443.3 EIE82889.1 - 0.43 10.6 23.6 0.28 11.2 3.3 2.9 1 1 1 2 2 2 0 AT-hook-containing transcription factor Globin PF00042.17 EIE82889.1 - 0.44 10.9 16.4 8.8 6.7 1.9 2.9 1 1 1 2 2 2 0 Globin DUF2450 PF10475.4 EIE82889.1 - 0.44 9.3 21.0 0.54 9.0 14.5 1.1 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) Het-C PF07217.6 EIE82889.1 - 0.44 8.6 12.2 0.51 8.4 8.4 1.0 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C DUF1451 PF07295.6 EIE82889.1 - 0.46 10.2 14.7 30 4.3 10.2 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1451) Sec23_helical PF04815.10 EIE82889.1 - 0.46 9.9 8.1 0.52 9.7 1.0 2.3 1 1 1 2 2 2 0 Sec23/Sec24 helical domain P4Ha_N PF08336.6 EIE82889.1 - 0.46 10.2 13.7 8.6 6.1 9.5 2.2 1 1 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DXP_synthase_N PF13292.1 EIE82889.1 - 0.48 9.3 14.9 21 3.8 10.3 2.1 1 1 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase Choline_kinase PF01633.15 EIE82889.1 - 0.49 9.9 7.8 0.57 9.7 5.4 1.1 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF4298 PF14131.1 EIE82889.1 - 0.52 10.2 7.5 4.3 7.2 1.3 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4298) Dynamitin PF04912.9 EIE82889.1 - 0.55 8.9 20.0 0.67 8.7 13.9 1.1 1 0 0 1 1 1 0 Dynamitin Mod_r PF07200.8 EIE82889.1 - 0.56 10.1 20.2 1.6 8.5 14.0 1.7 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Abi_C PF14355.1 EIE82889.1 - 0.57 10.1 9.2 2.6e+02 1.6 6.3 2.7 1 1 0 1 1 1 0 Abortive infection C-terminus Sec8_exocyst PF04048.9 EIE82889.1 - 0.6 9.7 20.7 3.1 7.4 14.4 1.9 1 1 0 1 1 1 0 Sec8 exocyst complex component specific domain Lipoprotein_6 PF01441.14 EIE82889.1 - 0.62 9.8 20.0 0.89 9.3 13.9 1.2 1 0 0 1 1 1 0 Lipoprotein DUF148 PF02520.12 EIE82889.1 - 0.67 9.7 25.4 1.3 8.8 17.6 1.4 1 1 0 1 1 1 0 Domain of unknown function DUF148 SNARE PF05739.14 EIE82889.1 - 0.68 9.6 22.4 9.9 5.9 11.9 2.6 1 1 1 2 2 2 0 SNARE domain PEP-utilisers_N PF05524.8 EIE82889.1 - 0.71 9.6 4.8 1.8 8.4 3.3 1.7 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal Serine_rich PF08824.5 EIE82889.1 - 0.73 9.5 13.6 3.7 7.2 9.4 2.0 1 1 0 1 1 1 0 Serine rich protein interaction domain DegS PF05384.6 EIE82889.1 - 0.74 9.0 24.7 0.52 9.5 9.3 2.1 1 1 1 2 2 2 0 Sensor protein DegS GLE1 PF07817.8 EIE82889.1 - 0.74 8.6 22.5 1 8.2 15.6 1.2 1 0 0 1 1 1 0 GLE1-like protein Lyase_8_N PF08124.6 EIE82889.1 - 0.76 8.5 9.9 1.7 7.4 6.9 1.5 1 1 0 1 1 1 0 Polysaccharide lyase family 8, N terminal alpha-helical domain DUF1759 PF03564.10 EIE82889.1 - 0.79 9.5 13.8 2.5e+02 1.4 9.5 2.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1759) Flu_NS2 PF00601.14 EIE82889.1 - 0.79 9.9 10.1 3.4 7.9 7.0 1.9 1 1 0 1 1 1 0 Influenza non-structural protein (NS2) DUF4132 PF13569.1 EIE82889.1 - 0.81 9.1 21.8 7 6.1 6.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4132) Z1 PF10593.4 EIE82889.1 - 0.81 8.8 11.2 1.3 8.1 7.7 1.4 1 0 0 1 1 1 0 Z1 domain 2OG-FeII_Oxy_2 PF13532.1 EIE82889.1 - 0.82 9.4 4.7 1 9.1 3.3 1.1 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily YscO PF07321.7 EIE82889.1 - 0.82 9.4 23.6 1.8 8.3 8.9 2.0 1 1 1 2 2 2 0 Type III secretion protein YscO Vps5 PF09325.5 EIE82889.1 - 0.83 8.8 16.9 10 5.2 11.6 2.3 1 1 0 1 1 1 0 Vps5 C terminal like DUF651 PF04895.7 EIE82889.1 - 0.85 9.2 15.6 2.4 7.7 4.5 2.1 1 1 1 2 2 2 0 Archaeal protein of unknown function (DUF651) CENP-Q PF13094.1 EIE82889.1 - 0.85 9.6 10.7 1.7 8.6 7.4 1.5 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit T4SS PF07996.6 EIE82889.1 - 0.9 9.3 35.5 1.5e+04 -10.4 24.6 3.1 1 1 0 1 1 0 0 Type IV secretion system proteins DUF885 PF05960.6 EIE82889.1 - 0.91 8.5 6.1 1.2 8.2 4.2 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) HsbA PF12296.3 EIE82889.1 - 0.92 9.3 12.3 4.9 7.0 8.6 2.1 1 1 0 1 1 1 0 Hydrophobic surface binding protein A DUF3418 PF11898.3 EIE82889.1 - 0.96 7.7 19.2 1.9 6.7 13.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3418) DUF1993 PF09351.5 EIE82889.1 - 0.97 9.3 17.6 23 4.8 12.2 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF1993) YtxH PF12732.2 EIE82889.1 - 0.98 9.8 21.4 8.8e+03 -2.9 14.8 2.4 1 1 0 1 1 0 0 YtxH-like protein DUF3708 PF12501.3 EIE82889.1 - 1 9.1 10.9 1.6 8.5 7.5 1.3 1 1 0 1 1 1 0 Phosphate ATP-binding cassette transporter FCH PF00611.18 EIE82889.1 - 1.1 9.5 14.4 46 4.3 10.0 3.1 1 1 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain Hormone_1 PF00103.15 EIE82889.1 - 1.1 8.5 9.5 2.5 7.3 6.6 1.6 1 1 0 1 1 1 0 Somatotropin hormone family Orbi_VP5 PF00901.12 EIE82889.1 - 1.1 7.4 18.2 1.3 7.1 12.6 1.1 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 OEP PF02321.13 EIE82889.1 - 1.1 8.8 14.3 0.56 9.7 3.6 2.0 1 1 1 2 2 2 0 Outer membrane efflux protein PilJ PF13675.1 EIE82889.1 - 1.1 9.6 7.0 5.2 7.4 4.8 2.0 1 1 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term EAP30 PF04157.11 EIE82889.1 - 1.1 8.3 14.7 18 4.3 10.1 2.2 1 1 0 1 1 1 0 EAP30/Vps36 family ATP-synt_B PF00430.13 EIE82889.1 - 1.1 9.0 17.7 2.3 8.0 12.3 1.5 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) DUF2365 PF10157.4 EIE82889.1 - 1.1 9.0 15.3 82 3.0 5.8 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2365) DUF357 PF04010.8 EIE82889.1 - 1.1 8.9 3.1 41 3.9 2.2 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF357) MKT1_C PF12246.3 EIE82889.1 - 1.1 8.1 8.4 6.7 5.6 5.8 1.9 1 1 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication Nup88 PF10168.4 EIE82889.1 - 1.1 6.9 23.9 1.3 6.7 16.6 1.0 1 0 0 1 1 1 0 Nuclear pore component CmcH_NodU PF02543.10 EIE82889.1 - 1.2 8.1 7.9 1.3 8.1 5.4 1.0 1 0 0 1 1 1 0 Carbamoyltransferase SpecificRecomb PF10136.4 EIE82889.1 - 1.3 6.9 11.9 1.8 6.5 8.3 1.2 1 0 0 1 1 1 0 Site-specific recombinase WES_acyltransf PF03007.11 EIE82889.1 - 1.3 8.5 10.8 34 3.8 7.5 2.1 1 1 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain Sulfatase_C PF14707.1 EIE82889.1 - 1.3 9.2 21.3 1.5e+04 -3.8 14.8 3.0 1 1 0 1 1 0 0 C-terminal region of aryl-sulfatase DUF4239 PF14023.1 EIE82889.1 - 1.4 8.2 15.6 7.6 5.8 10.8 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF4239) bZIP_1 PF00170.16 EIE82889.1 - 1.4 8.9 13.1 1.6e+03 -0.9 9.1 2.8 1 1 0 1 1 0 0 bZIP transcription factor TPR_MLP1_2 PF07926.7 EIE82889.1 - 1.4 8.6 18.0 6.1 6.5 12.5 1.8 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein RP-C_C PF11800.3 EIE82889.1 - 1.4 8.5 7.6 3.2 7.4 5.3 1.6 1 1 0 1 1 1 0 Replication protein C C-terminal region PilO PF04350.8 EIE82889.1 - 1.5 8.7 21.7 1.3 8.9 7.3 2.1 1 1 1 2 2 2 0 Pilus assembly protein, PilO ADIP PF11559.3 EIE82889.1 - 1.5 8.7 19.2 2.2 8.1 13.3 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF911 PF06023.7 EIE82889.1 - 1.5 7.9 12.9 1.7 7.7 8.9 1.0 1 0 0 1 1 1 0 Archaeal protein of unknown function (DUF911) hDGE_amylase PF14701.1 EIE82889.1 - 1.5 7.6 12.3 1.8 7.3 8.5 1.1 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme Tropomyosin_1 PF12718.2 EIE82889.1 - 1.5 8.6 14.1 2.9 7.7 9.8 1.5 1 1 0 1 1 1 0 Tropomyosin like PRD PF00874.15 EIE82889.1 - 1.5 8.9 4.2 21 5.3 2.9 2.3 1 1 0 1 1 1 0 PRD domain Phage_GPO PF05929.6 EIE82889.1 - 1.6 7.9 15.5 1.9 7.6 10.7 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase GlnE PF03710.10 EIE82889.1 - 1.6 7.9 9.0 3.1 6.9 6.2 1.5 1 1 0 1 1 1 0 Glutamate-ammonia ligase adenylyltransferase Cauli_AT PF03233.8 EIE82889.1 - 1.6 8.3 26.4 59 3.3 18.3 2.2 1 1 0 1 1 1 0 Aphid transmission protein Dynein_heavy PF03028.10 EIE82889.1 - 1.6 6.6 12.6 1.8 6.5 8.8 1.0 1 0 0 1 1 1 0 Dynein heavy chain and region D6 of dynein motor Bac_GDH PF05088.7 EIE82889.1 - 1.7 5.9 19.3 6 4.1 13.3 1.7 1 1 0 1 1 1 0 Bacterial NAD-glutamate dehydrogenase DUF3810 PF12725.2 EIE82889.1 - 1.8 7.4 13.2 3.9 6.2 9.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) ERp29 PF07749.7 EIE82889.1 - 1.8 9.2 19.8 2.2e+02 2.5 13.7 2.6 1 1 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain His_Phos_2 PF00328.17 EIE82889.1 - 1.8 7.8 7.0 2.3 7.4 4.9 1.2 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) DUF812 PF05667.6 EIE82889.1 - 1.8 6.9 24.7 3.5 6.0 17.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Apc4 PF12896.2 EIE82889.1 - 1.9 7.7 12.5 1.4e+02 1.6 8.7 2.5 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 4 Peptidase_M26_C PF07580.9 EIE82889.1 - 1.9 6.6 14.7 2.3 6.3 10.2 1.1 1 0 0 1 1 1 0 M26 IgA1-specific Metallo-endopeptidase C-terminal region DUF607 PF04678.8 EIE82889.1 - 1.9 8.3 13.1 2.5 8.0 9.1 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF607 Hom_end_hint PF05203.11 EIE82889.1 - 2 8.1 14.0 2.3 7.9 9.7 1.1 1 0 0 1 1 1 0 Hom_end-associated Hint YicC_N PF03755.8 EIE82889.1 - 2 8.3 11.4 3.6 7.4 7.9 1.4 1 1 0 1 1 1 0 YicC-like family, N-terminal region Striatin PF08232.7 EIE82889.1 - 2.1 8.6 16.9 2.9 8.1 11.7 1.2 1 0 0 1 1 1 0 Striatin family DUF4359 PF14271.1 EIE82889.1 - 2.1 8.7 17.0 0.69 10.3 5.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4359) Vps51 PF08700.6 EIE82889.1 - 2.2 8.1 14.7 1.8e+02 2.0 10.2 2.9 1 1 0 1 1 1 0 Vps51/Vps67 Adeno_PIX PF03955.9 EIE82889.1 - 2.2 8.8 13.0 1.5e+02 2.9 9.0 2.1 1 1 0 1 1 1 0 Adenovirus hexon-associated protein (IX) MIS13 PF08202.6 EIE82889.1 - 2.3 7.2 14.8 3.1 6.7 10.3 1.2 1 0 0 1 1 1 0 Mis12-Mtw1 protein family GatB_Yqey PF02637.13 EIE82889.1 - 2.3 7.9 21.0 17 5.1 14.5 2.0 1 1 0 1 1 1 0 GatB domain Snf7 PF03357.16 EIE82889.1 - 2.3 7.5 32.3 35 3.7 22.8 1.9 1 1 0 1 1 1 0 Snf7 Tektin PF03148.9 EIE82889.1 - 2.3 6.6 17.7 5.4 5.4 2.3 1.8 1 1 1 2 2 2 0 Tektin family DUF2972 PF11186.3 EIE82889.1 - 2.4 8.0 13.6 3 7.6 9.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2972) FliJ PF02050.11 EIE82889.1 - 2.4 8.2 28.5 2.5 8.1 8.1 2.2 1 1 1 2 2 2 0 Flagellar FliJ protein ApoL PF05461.6 EIE82889.1 - 2.5 7.2 20.3 4.4 6.4 14.1 1.4 1 1 0 1 1 1 0 Apolipoprotein L DUF4446 PF14584.1 EIE82889.1 - 2.5 7.9 17.8 25 4.6 12.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF4446) Lebercilin PF15619.1 EIE82889.1 - 2.5 7.4 20.6 5.2 6.4 14.3 1.4 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease FANCI_S3 PF14677.1 EIE82889.1 - 2.5 7.4 17.4 3 7.1 12.0 1.0 1 0 0 1 1 1 0 FANCI solenoid 3 PSD4 PF07631.6 EIE82889.1 - 2.5 8.4 6.5 3.9 7.8 4.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1592) FtsQ PF03799.10 EIE82889.1 - 2.6 8.2 9.7 3.8e+02 1.2 6.7 2.7 1 1 0 1 1 1 0 Cell division protein FtsQ DUF2428 PF10350.4 EIE82889.1 - 2.7 6.9 10.6 3.9 6.4 7.3 1.3 1 0 0 1 1 1 0 Putative death-receptor fusion protein (DUF2428) Taxilin PF09728.4 EIE82889.1 - 2.7 6.9 28.9 12 4.8 20.0 1.8 1 1 0 1 1 1 0 Myosin-like coiled-coil protein ArsA_ATPase PF02374.10 EIE82889.1 - 2.7 6.9 17.4 18 4.2 12.1 1.9 1 1 0 1 1 1 0 Anion-transporting ATPase Y_phosphatase3 PF13350.1 EIE82889.1 - 2.8 8.1 6.1 5.7 7.1 4.2 1.6 1 1 0 1 1 1 0 Tyrosine phosphatase family DASH_Dad2 PF08654.5 EIE82889.1 - 3 7.9 15.5 21 5.1 1.1 2.4 1 1 1 2 2 2 0 DASH complex subunit Dad2 CDO_I PF05995.7 EIE82889.1 - 3 6.9 16.2 4.2e+02 -0.1 11.2 2.1 1 1 0 1 1 1 0 Cysteine dioxygenase type I UPF0147 PF03685.8 EIE82889.1 - 3.1 7.7 14.8 2 8.3 3.2 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0147) Ran-binding PF05508.6 EIE82889.1 - 3.2 6.5 16.6 9.3 5.0 11.5 1.7 1 1 0 1 1 1 0 RanGTP-binding protein Terpene_synth PF01397.16 EIE82889.1 - 3.4 7.0 19.8 5.3 6.3 5.7 2.5 1 1 1 2 2 2 0 Terpene synthase, N-terminal domain DUF1465 PF07323.7 EIE82889.1 - 3.4 7.2 8.7 5.5 6.5 6.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1465) DUF4400 PF14348.1 EIE82889.1 - 3.5 6.9 6.3 4.6 6.5 4.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4400) IFT20 PF14931.1 EIE82889.1 - 3.5 7.5 23.2 34 4.3 4.6 2.9 1 1 1 2 2 2 0 Intraflagellar transport complex B, subunit 20 DUF241 PF03087.9 EIE82889.1 - 3.5 7.0 22.8 4.6 6.6 15.8 1.1 1 0 0 1 1 1 0 Arabidopsis protein of unknown function DDE_Tnp_IS66 PF03050.9 EIE82889.1 - 3.6 6.7 9.0 7.6 5.6 6.2 1.6 1 1 0 1 1 1 0 Transposase IS66 family Phycobilisome PF00502.14 EIE82889.1 - 3.7 7.3 13.8 1.2 8.8 3.1 2.1 1 1 1 2 2 2 0 Phycobilisome protein COMP PF11598.3 EIE82889.1 - 3.7 7.7 25.8 1.5e+04 -6.5 17.9 3.5 1 1 0 1 1 0 0 Cartilage oligomeric matrix protein CPG4 PF15481.1 EIE82889.1 - 3.8 7.9 9.9 6.8 7.1 6.8 1.5 1 1 0 1 1 1 0 Chondroitin proteoglycan 4 Reticulon PF02453.12 EIE82889.1 - 3.9 7.0 15.0 5.4e+02 0.0 10.4 2.4 1 1 0 1 1 0 0 Reticulon DUF773 PF05600.7 EIE82889.1 - 4 6.0 22.6 5.3 5.6 15.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF773) 5_3_exonuc PF01367.15 EIE82889.1 - 4.1 7.7 10.3 27 5.0 7.1 2.0 1 1 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold YkuI_C PF10388.4 EIE82889.1 - 4.1 7.0 18.6 7.5 6.1 6.0 2.1 1 1 1 2 2 2 0 EAL-domain associated signalling protein domain YtzH PF14165.1 EIE82889.1 - 4.3 7.6 21.0 2.6e+03 -1.4 14.6 2.8 1 1 0 1 1 0 0 YtzH-like protein COG6 PF06419.6 EIE82889.1 - 4.3 5.3 23.9 31 2.5 16.6 1.9 1 1 0 1 1 1 0 Conserved oligomeric complex COG6 DUF4618 PF15397.1 EIE82889.1 - 4.4 6.5 29.5 48 3.1 20.5 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) DUF4208 PF13907.1 EIE82889.1 - 4.4 7.5 18.8 7.7e+02 0.3 13.0 2.3 1 1 0 1 1 0 0 Domain of unknown function (DUF4208) Utp12 PF04003.7 EIE82889.1 - 4.4 7.2 13.4 52 3.7 9.2 2.4 1 1 0 1 1 1 0 Dip2/Utp12 Family CRISPR_Cse1 PF09481.5 EIE82889.1 - 4.8 5.8 8.5 14 4.3 5.9 1.7 1 1 0 1 1 1 0 CRISPR-associated protein Cse1 (CRISPR_cse1) DUF4600 PF15372.1 EIE82889.1 - 5 7.3 21.2 48 4.1 14.7 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4600) Baculo_IE-1 PF05290.6 EIE82889.1 - 5.1 6.8 20.0 3e+02 1.1 13.9 2.1 1 1 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Filo_VP35 PF02097.10 EIE82889.1 - 5.1 6.1 18.1 9.3 5.3 12.5 1.4 1 1 0 1 1 1 0 Filoviridae VP35 Cytochrom_C_2 PF01322.15 EIE82889.1 - 5.2 7.6 12.9 40 4.7 9.0 2.1 1 1 0 1 1 1 0 Cytochrome C' SLT_2 PF13406.1 EIE82889.1 - 5.2 5.8 11.0 6.2 5.6 7.6 1.1 1 0 0 1 1 1 0 Transglycosylase SLT domain Transposase_22 PF02994.9 EIE82889.1 - 5.3 5.4 21.0 8.7 4.7 14.6 1.3 1 0 0 1 1 1 0 L1 transposable element GCIP PF13324.1 EIE82889.1 - 5.3 6.1 27.3 2.3e+02 0.8 18.9 2.5 1 1 0 1 1 1 0 Grap2 and cyclin-D-interacting Bacillus_HBL PF05791.6 EIE82889.1 - 5.5 6.3 17.9 20 4.4 12.4 1.8 1 1 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) PspA_IM30 PF04012.7 EIE82889.1 - 5.7 6.2 30.0 3.6 6.8 11.2 2.0 1 1 1 2 2 2 0 PspA/IM30 family DUF932 PF06067.6 EIE82889.1 - 5.7 6.1 15.6 24 4.1 2.6 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF932) Muted PF14942.1 EIE82889.1 - 5.8 6.7 19.1 11 5.8 13.2 1.4 1 1 0 1 1 1 0 Organelle biogenesis, Muted-like protein FlpD PF02662.11 EIE82889.1 - 5.8 6.6 11.5 2.1e+02 1.6 8.0 2.5 1 1 0 1 1 1 0 Methyl-viologen-reducing hydrogenase, delta subunit Retrotrans_gag PF03732.12 EIE82889.1 - 6 7.0 7.6 45 4.2 5.3 2.0 1 1 0 1 1 1 0 Retrotransposon gag protein Aminotran_1_2 PF00155.16 EIE82889.1 - 6.2 5.6 11.2 32 3.3 7.7 1.9 1 1 0 1 1 1 0 Aminotransferase class I and II C9orf72-like PF15019.1 EIE82889.1 - 6.2 5.9 20.8 0.8 8.9 6.2 2.0 1 1 1 2 2 2 0 C9orf72-like protein family DUF3323 PF11796.3 EIE82889.1 - 6.5 6.0 9.8 15 4.8 6.8 1.5 1 1 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) Imm5 PF14423.1 EIE82889.1 - 6.5 6.3 9.6 6.9 6.2 6.6 1.1 1 0 0 1 1 1 0 Immunity protein Imm5 phage_tail_N PF08400.5 EIE82889.1 - 6.8 6.4 17.4 23 4.6 1.6 3.1 1 1 1 2 2 1 0 Prophage tail fibre N-terminal ENTH PF01417.15 EIE82889.1 - 7 6.5 14.9 46 3.8 10.3 1.9 1 1 0 1 1 1 0 ENTH domain RRF_GI PF12614.3 EIE82889.1 - 7.2 6.4 15.4 12 5.7 10.7 1.4 1 1 0 1 1 1 0 Ribosome recycling factor DUF1484 PF07363.6 EIE82889.1 - 7.2 7.0 18.4 4.3e+03 -2.0 12.8 2.3 1 1 0 1 1 0 0 Protein of unknown function (DUF1484) FTCD_C PF04961.7 EIE82889.1 - 7.3 5.9 11.2 14 5.0 7.7 1.4 1 1 0 1 1 1 0 Formiminotransferase-cyclodeaminase FAD-SLDH PF12318.3 EIE82889.1 - 7.4 6.2 10.8 11 5.6 3.7 2.0 1 1 1 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase DUF2422 PF10337.4 EIE82889.1 - 7.8 5.1 13.7 14 4.3 9.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2422) Sin3_corepress PF08295.7 EIE82889.1 - 7.9 6.3 9.4 32 4.3 1.1 3.1 1 1 2 3 3 3 0 Sin3 family co-repressor Telomere_reg-2 PF10193.4 EIE82889.1 - 8 6.7 12.5 10 6.4 8.7 1.1 1 0 0 1 1 1 0 Telomere length regulation protein SH3BP5 PF05276.9 EIE82889.1 - 8 5.6 20.0 10 5.3 13.9 1.1 1 0 0 1 1 1 0 SH3 domain-binding protein 5 (SH3BP5) IDO PF01231.13 EIE82889.1 - 8.3 4.7 14.5 3e+02 -0.4 10.0 2.0 1 1 0 1 1 1 0 Indoleamine 2,3-dioxygenase Gp58 PF07902.6 EIE82889.1 - 8.3 4.4 17.7 9.3 4.3 12.2 1.0 1 0 0 1 1 1 0 gp58-like protein DUF3414 PF11894.3 EIE82889.1 - 8.9 3.0 12.9 11 2.7 9.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3414) DUF1342 PF07072.6 EIE82889.1 - 9.3 5.8 15.9 3.2e+02 0.8 11.1 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1342) MMPL PF03176.10 EIE82889.1 - 9.8 4.7 15.6 16 4.0 10.9 1.4 1 1 0 1 1 1 0 MMPL family PSD2 PF07624.6 EIE82889.1 - 9.9 5.8 10.0 7.8 6.2 0.8 3.1 1 1 2 3 3 2 0 Protein of unknown function (DUF1585) Ax_dynein_light PF10211.4 EIE82889.1 - 10 5.9 18.0 23 4.7 12.4 1.6 1 1 0 1 1 1 0 Axonemal dynein light chain Mastoparan PF08249.6 EIE82890.1 - 0.78 10.4 2.7 2.1 9.0 1.9 1.8 1 0 0 1 1 1 0 Mastoparan protein HTH_29 PF13551.1 EIE82891.1 - 0.0012 18.9 0.0 0.0034 17.5 0.0 1.8 1 1 1 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.1 EIE82891.1 - 0.012 16.4 0.0 0.027 15.2 0.0 1.7 2 0 0 2 2 2 0 Homeodomain-like domain HTH_7 PF02796.10 EIE82891.1 - 0.016 15.0 0.1 0.11 12.3 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HCNGP PF07818.8 EIE82891.1 - 0.042 13.8 0.2 0.09 12.8 0.1 1.5 1 0 0 1 1 1 0 HCNGP-like protein Glucan_synthase PF02364.10 EIE82892.1 - 1.1e-133 446.9 0.4 1.2e-133 446.8 0.3 1.0 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 EIE82893.1 - 9e-32 109.4 0.2 2.1e-31 108.2 0.1 1.7 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Bot1p PF12298.3 EIE82897.1 - 1.3e-12 48.0 8.9 8.2e-07 29.1 0.3 2.7 2 1 1 3 3 3 2 Eukaryotic mitochondrial regulator protein Actin PF00022.14 EIE82898.1 - 4.3e-116 387.5 0.0 4.9e-116 387.3 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EIE82898.1 - 6.3e-06 25.0 0.0 1.9e-05 23.4 0.0 1.8 1 1 0 1 1 1 1 MreB/Mbl protein PilM_2 PF11104.3 EIE82898.1 - 0.17 10.7 0.0 0.3 9.9 0.0 1.3 1 0 0 1 1 1 0 Type IV pilus assembly protein PilM; Put_Phosphatase PF06888.7 EIE82899.1 - 2.9e-47 160.8 0.3 3.6e-47 160.5 0.2 1.0 1 0 0 1 1 1 1 Putative Phosphatase HAD PF12710.2 EIE82899.1 - 0.00027 21.1 0.0 0.00039 20.6 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EIE82899.1 - 0.0016 18.0 0.2 0.86 9.1 0.0 2.3 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.7 EIE82899.1 - 0.0026 17.1 0.2 0.0049 16.2 0.1 1.5 2 0 0 2 2 2 1 Pyrimidine 5'-nucleotidase (UMPH-1) Hydrolase PF00702.21 EIE82899.1 - 0.0051 17.2 0.0 0.0077 16.6 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EIE82899.1 - 0.032 14.4 0.0 0.076 13.2 0.0 1.8 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase CH PF00307.26 EIE82900.1 - 6.4e-77 254.5 0.0 1.4e-18 66.9 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EIE82900.1 - 6.4e-13 48.1 0.0 0.00029 20.4 0.0 4.3 4 0 0 4 4 4 2 CAMSAP CH domain EF-hand_7 PF13499.1 EIE82900.1 - 4.1e-09 36.4 1.2 3.1e-08 33.6 0.6 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EIE82900.1 - 4e-08 31.9 2.2 0.00041 19.4 0.2 3.7 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.1 EIE82900.1 - 7.5e-06 25.0 1.6 0.0015 17.7 0.1 2.9 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 EIE82900.1 - 4.3e-05 23.0 0.8 0.0012 18.5 0.2 2.9 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.1 EIE82900.1 - 0.0038 16.8 0.6 0.65 9.6 0.2 2.7 2 0 0 2 2 2 1 EF-hand domain pair Porin_OmpG PF09381.5 EIE82900.1 - 0.11 11.6 0.2 0.17 10.9 0.2 1.2 1 0 0 1 1 1 0 Outer membrane protein G (OmpG) CotH PF08757.6 EIE82902.1 - 6.9e-40 137.2 1.0 1.1e-39 136.5 0.7 1.3 1 0 0 1 1 1 1 CotH protein Ricin_B_lectin PF00652.17 EIE82903.1 - 0.00037 20.5 4.1 0.0027 17.7 2.5 2.3 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 EIE82903.1 - 0.0054 17.0 3.5 0.11 12.9 1.2 2.0 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like PPO1_DWL PF12142.3 EIE82903.1 - 0.05 13.1 0.6 0.11 12.0 0.4 1.5 1 0 0 1 1 1 0 Polyphenol oxidase middle domain 2-oxoacid_dh PF00198.18 EIE82905.1 - 7.5e-79 264.2 0.2 9.5e-79 263.9 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EIE82905.1 - 5.4e-15 54.7 0.6 9.7e-15 53.9 0.5 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme GCV_H PF01597.14 EIE82905.1 - 8.7e-05 22.2 0.5 0.00021 20.9 0.3 1.6 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl_2 PF13533.1 EIE82905.1 - 0.013 15.0 1.1 0.09 12.4 0.1 2.3 1 1 1 2 2 2 0 Biotin-lipoyl like MIP-T3 PF10243.4 EIE82905.1 - 0.018 13.5 17.1 0.024 13.1 11.9 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 RnfC_N PF13375.1 EIE82905.1 - 0.021 14.5 0.3 0.053 13.2 0.2 1.6 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain RLL PF10036.4 EIE82905.1 - 0.14 11.5 6.7 0.21 10.9 4.7 1.2 1 0 0 1 1 1 0 Putative carnitine deficiency-associated protein Cytomega_UL84 PF06284.6 EIE82905.1 - 0.27 9.6 1.9 0.98 7.7 0.0 2.1 2 0 0 2 2 2 0 Cytomegalovirus UL84 protein RR_TM4-6 PF06459.7 EIE82905.1 - 0.55 10.0 13.4 0.75 9.6 9.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GAGA_bind PF06217.7 EIE82905.1 - 2 8.3 6.9 2.8 7.8 4.8 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family SpoIIIAH PF12685.2 EIE82905.1 - 9.1 5.7 15.1 9.2 5.7 6.7 2.2 2 0 0 2 2 2 0 SpoIIIAH-like protein Glyco_hydro_18 PF00704.23 EIE82906.1 - 1.8e-73 247.9 9.4 1.8e-73 247.9 6.5 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 CBM_5_12 PF02839.9 EIE82906.1 - 3e-13 49.0 11.0 1.2e-12 47.1 7.6 2.2 1 0 0 1 1 1 1 Carbohydrate binding domain Gon7 PF08738.5 EIE82907.1 - 4e-05 23.5 4.2 0.00014 21.8 2.9 2.1 1 1 0 1 1 1 1 Gon7 family DUF4611 PF15387.1 EIE82907.1 - 0.02 14.9 9.7 0.024 14.7 6.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4611) CBP4 PF07960.6 EIE82907.1 - 0.27 10.8 4.7 0.35 10.4 3.2 1.1 1 0 0 1 1 1 0 CBP4 PI3K_1B_p101 PF10486.4 EIE82907.1 - 0.58 7.6 3.1 0.57 7.6 2.1 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Sigma70_ner PF04546.8 EIE82907.1 - 2.9 7.4 10.6 3.3 7.2 7.3 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region GST_N_3 PF13417.1 EIE82908.1 - 2.8e-13 49.9 0.1 7.3e-13 48.5 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIE82908.1 - 6e-10 38.9 0.1 1.2e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EIE82908.1 - 1.2e-05 25.2 0.0 2e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EIE82908.1 - 0.00048 19.9 0.0 0.00085 19.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EIE82908.1 - 0.0015 18.9 0.0 0.0068 16.8 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain INTS5_N PF14837.1 EIE82908.1 - 0.0021 17.4 0.0 0.0031 16.9 0.0 1.2 1 0 0 1 1 1 1 Integrator complex subunit 5 N-terminus DUF3414 PF11894.3 EIE82910.1 - 1.5e-184 615.5 51.2 2.4e-184 614.9 35.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) Suf PF05843.9 EIE82910.1 - 0.00076 19.2 11.4 0.0022 17.7 7.9 1.7 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) Band_3_cyto PF07565.8 EIE82910.1 - 0.0019 17.7 8.6 0.0069 15.9 5.9 1.9 1 0 0 1 1 1 1 Band 3 cytoplasmic domain DUF4557 PF15101.1 EIE82910.1 - 0.0023 17.8 19.8 0.0061 16.4 13.7 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4557) DDHD PF02862.12 EIE82910.1 - 0.0055 16.5 10.6 0.016 14.9 7.3 1.8 1 0 0 1 1 1 1 DDHD domain Neur_chan_memb PF02932.11 EIE82910.1 - 0.011 15.5 1.2 0.024 14.5 0.8 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Pex14_N PF04695.8 EIE82910.1 - 0.026 14.5 18.6 0.065 13.2 12.9 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region YbgT_YccB PF08173.6 EIE82910.1 - 0.39 10.5 1.1 2.6 7.9 0.1 2.5 2 0 0 2 2 2 0 Membrane bound YbgT-like protein Peptidase_S49_N PF08496.5 EIE82910.1 - 1.1 9.0 14.7 4.8 6.9 10.2 2.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF4175 PF13779.1 EIE82910.1 - 1.3 6.6 43.1 2 6.0 29.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF940 PF06082.6 EIE82910.1 - 1.7 7.0 11.7 2.7 6.4 8.1 1.2 1 0 0 1 1 1 0 Bacterial putative lipoprotein (DUF940) PAT1 PF09770.4 EIE82910.1 - 1.9 6.6 38.8 3.2 5.8 26.9 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Gti1_Pac2 PF09729.4 EIE82910.1 - 2.1 8.1 13.7 29 4.4 7.1 3.2 3 0 0 3 3 3 0 Gti1/Pac2 family AUX_IAA PF02309.11 EIE82910.1 - 2.4 7.8 14.0 5.5 6.6 9.7 1.5 1 0 0 1 1 1 0 AUX/IAA family RP-C_C PF11800.3 EIE82910.1 - 2.5 7.7 16.2 0.55 9.9 8.4 1.9 2 0 0 2 2 2 0 Replication protein C C-terminal region TFIIA PF03153.8 EIE82910.1 - 3.6 7.3 30.4 6.5 6.5 21.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4407 PF14362.1 EIE82910.1 - 6 5.7 17.9 10 4.9 12.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Gag_spuma PF03276.9 EIE82910.1 - 7.2 4.8 32.5 11 4.1 22.5 1.2 1 0 0 1 1 1 0 Spumavirus gag protein FLO_LFY PF01698.11 EIE82910.1 - 8.4 5.1 15.0 14 4.3 10.4 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein SprA-related PF12118.3 EIE82910.1 - 8.8 5.5 43.2 15 4.7 30.0 1.2 1 0 0 1 1 1 0 SprA-related family Tim17 PF02466.14 EIE82911.1 - 5e-12 45.9 10.5 6.5e-12 45.6 7.3 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Bacteriocin_IIc PF10439.4 EIE82911.1 - 0.4 10.8 12.1 0.32 11.1 1.5 2.2 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide SF3b1 PF08920.5 EIE82912.1 - 1.2e-39 135.6 3.8 1.2e-39 135.6 2.6 2.4 1 1 1 2 2 2 2 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 EIE82912.1 - 1.6e-14 53.9 4.4 0.0055 16.9 0.0 7.2 5 2 2 7 7 7 3 HEAT repeats HEAT PF02985.17 EIE82912.1 - 1.3e-12 46.6 4.6 0.26 11.4 0.0 8.9 9 0 0 9 9 9 3 HEAT repeat HEAT_EZ PF13513.1 EIE82912.1 - 4.3e-10 39.7 1.9 1.8 9.1 0.0 8.1 7 2 1 9 9 9 3 HEAT-like repeat Adaptin_N PF01602.15 EIE82912.1 - 5e-06 25.1 2.5 0.013 13.8 0.1 3.0 2 1 0 2 2 2 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.2 EIE82912.1 - 0.00026 21.3 4.3 0.9 9.9 0.0 4.5 6 0 0 6 6 6 2 Vacuolar 14 Fab1-binding region Arm PF00514.18 EIE82912.1 - 0.0071 16.1 4.2 9 6.2 0.0 5.4 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat NodA PF02474.10 EIE82912.1 - 0.056 12.7 0.1 0.14 11.4 0.0 1.6 1 0 0 1 1 1 0 Nodulation protein A (NodA) Dopey_N PF04118.9 EIE82912.1 - 0.058 12.1 1.3 4.9 5.8 0.0 3.4 3 0 0 3 3 3 0 Dopey, N-terminal DUF1675 PF07897.6 EIE82912.1 - 3.4 7.4 8.3 6 6.6 5.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Complex1_49kDa PF00346.14 EIE82913.1 - 2.8e-128 426.6 0.0 3.7e-128 426.2 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.14 EIE82913.1 - 0.011 14.6 0.0 0.021 13.6 0.0 1.5 2 0 0 2 2 2 0 Nickel-dependent hydrogenase ACOX PF01756.14 EIE82914.1 - 3.3e-50 170.0 0.0 6.5e-50 169.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.14 EIE82914.1 - 4.5e-15 54.8 1.6 8.3e-15 54.0 0.4 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 EIE82914.1 - 1.2e-08 35.1 1.8 2.3e-07 31.0 0.7 2.8 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.1 EIE82914.1 - 0.0016 18.7 0.0 0.0048 17.1 0.0 1.9 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal FGGY_C PF02782.11 EIE82919.1 - 1.9e-45 154.9 0.0 2.9e-45 154.3 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EIE82919.1 - 1e-24 87.1 0.1 2.9e-24 85.7 0.0 1.8 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain RhoGEF PF00621.15 EIE82920.1 - 1.1e-36 126.3 6.0 1.2e-36 126.2 4.1 1.0 1 0 0 1 1 1 1 RhoGEF domain TMA7 PF09072.5 EIE82922.1 - 3.6e-27 94.6 20.7 3.9e-27 94.4 14.4 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 Pet20 PF08692.5 EIE82922.1 - 0.18 11.7 0.7 0.2 11.6 0.5 1.1 1 0 0 1 1 1 0 Mitochondrial protein Pet20 Sel1 PF08238.7 EIE82923.1 - 1e-147 477.3 55.5 7.8e-14 51.7 0.8 15.3 15 1 0 15 15 15 15 Sel1 repeat TPR_6 PF13174.1 EIE82923.1 - 1.2e-07 31.7 14.2 4.5 7.9 0.0 8.8 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_17 PF13431.1 EIE82923.1 - 0.00048 20.1 10.6 2.7 8.4 0.1 8.2 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_11 PF13414.1 EIE82923.1 - 0.0082 15.7 35.0 0.13 11.9 1.5 8.9 4 2 5 9 9 9 2 TPR repeat TPR_14 PF13428.1 EIE82923.1 - 1.4 9.7 10.0 32 5.5 0.0 6.7 7 2 2 9 9 9 0 Tetratricopeptide repeat PPR PF01535.15 EIE82923.1 - 1.6 8.9 7.4 2.7 8.1 0.1 4.8 6 0 0 6 6 6 0 PPR repeat DUF3021 PF11457.3 EIE82924.1 - 0.018 14.9 0.4 0.12 12.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3021) DUF4318 PF14201.1 EIE82924.1 - 0.029 14.2 0.0 0.068 13.0 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4318) DUF2367 PF10164.4 EIE82924.1 - 0.1 12.4 0.0 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2367) Fumerase_C PF05683.7 EIE82924.1 - 0.14 11.2 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Fumarase C-terminus MRP-S26 PF14943.1 EIE82925.1 - 0.007 15.9 3.2 0.007 15.9 2.2 2.3 2 0 0 2 2 2 1 Mitochondrial ribosome subunit S26 DUF2269 PF10027.4 EIE82925.1 - 0.042 13.6 0.1 0.062 13.0 0.1 1.2 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2269) PalH PF08733.5 EIE82925.1 - 0.11 11.3 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 PalH/RIM21 VSG_B PF13206.1 EIE82925.1 - 3.4 6.6 6.1 0.17 10.9 0.3 1.7 2 0 0 2 2 2 0 Trypanosomal VSG domain zf-C2H2 PF00096.21 EIE82927.1 - 2.3e-08 33.8 31.4 1.1e-05 25.4 1.1 4.7 6 0 0 6 6 6 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIE82927.1 - 6e-08 32.6 22.4 2.8e-05 24.1 2.9 4.4 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EIE82927.1 - 8.9e-07 28.8 28.0 0.0082 16.4 0.5 4.6 6 0 0 6 6 6 3 C2H2-type zinc finger zf-C2HC_2 PF13913.1 EIE82927.1 - 0.0086 15.7 1.5 0.033 13.8 1.0 2.1 1 0 0 1 1 1 1 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.3 EIE82927.1 - 0.015 15.4 4.3 2.3 8.4 0.0 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.13 EIE82927.1 - 0.015 15.6 8.2 1.8 9.0 0.0 3.3 2 1 2 4 4 4 0 TRAF-type zinc finger zf-BED PF02892.10 EIE82927.1 - 1.7 8.5 9.2 19 5.1 0.1 2.9 2 1 0 2 2 2 0 BED zinc finger NUC153 PF08159.7 EIE82929.1 - 1.5e-11 43.6 0.6 2.8e-11 42.8 0.4 1.5 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.27 EIE82929.1 - 0.023 14.5 0.1 2.7 8.0 0.0 4.0 5 0 0 5 5 5 0 WD domain, G-beta repeat AbfB PF05270.8 EIE82929.1 - 0.082 12.6 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Alpha-L-arabinofuranosidase B (ABFB) AhpC-TSA PF00578.16 EIE82930.1 - 9.8e-11 41.4 0.0 1.5e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EIE82930.1 - 0.0019 17.7 0.0 0.0024 17.4 0.0 1.2 1 0 0 1 1 1 1 Redoxin BTD PF09270.5 EIE82931.1 - 1e-22 80.5 0.1 2.8e-19 69.4 0.1 3.3 2 1 0 2 2 2 2 Beta-trefoil DNA-binding domain LAG1-DNAbind PF09271.6 EIE82931.1 - 1.2e-14 54.9 1.9 3.8e-14 53.3 1.2 2.0 1 1 0 1 1 1 1 LAG1, DNA binding TIG PF01833.19 EIE82931.1 - 1.8e-06 27.8 1.2 6.6e-05 22.8 0.0 3.1 3 1 0 3 3 3 1 IPT/TIG domain PHD PF00628.24 EIE82932.1 - 8.2e-10 38.2 9.4 8.2e-10 38.2 6.5 2.8 3 0 0 3 3 3 1 PHD-finger zf-C2H2_jaz PF12171.3 EIE82932.1 - 0.0023 18.0 1.2 0.009 16.1 0.8 2.1 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding PHD_2 PF13831.1 EIE82932.1 - 0.012 14.8 6.0 0.036 13.3 2.1 2.5 2 0 0 2 2 2 0 PHD-finger zf-FPG_IleRS PF06827.9 EIE82932.1 - 0.015 14.9 1.3 0.048 13.3 0.2 2.5 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS zf-RING-like PF08746.6 EIE82932.1 - 2.5 8.1 16.0 0.08 12.9 6.3 2.1 2 1 0 2 2 2 0 RING-like domain HLH PF00010.21 EIE82933.1 - 4.1e-13 48.8 0.4 9e-13 47.7 0.3 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Cytadhesin_P30 PF07271.6 EIE82933.1 - 0.18 11.0 10.3 0.25 10.5 7.1 1.2 1 0 0 1 1 1 0 Cytadhesin P30/P32 RR_TM4-6 PF06459.7 EIE82933.1 - 0.25 11.2 16.7 0.36 10.6 11.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Pneumo_att_G PF05539.6 EIE82933.1 - 0.61 9.3 9.1 0.82 8.9 6.3 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Auxin_repressed PF05564.7 EIE82933.1 - 2.5 8.7 8.1 4.8 7.8 4.0 2.2 1 1 1 2 2 2 0 Dormancy/auxin associated protein Asp-B-Hydro_N PF05279.6 EIE82933.1 - 4.4 7.0 12.3 5.5 6.7 8.5 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region PseudoU_synth_2 PF00849.17 EIE82934.1 - 4.6e-17 62.3 0.0 5.7e-17 62.0 0.0 1.1 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.20 EIE82934.1 - 0.011 15.1 0.0 0.021 14.2 0.0 1.5 1 0 0 1 1 1 0 S4 domain RRM_1 PF00076.17 EIE82935.1 - 3.3e-27 93.9 0.0 1.2e-12 47.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE82935.1 - 6.8e-21 74.0 0.0 2.6e-10 40.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE82935.1 - 0.00017 21.4 0.0 0.56 10.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3899 PF13038.1 EIE82936.1 - 0.087 12.9 1.1 0.19 11.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) Histone_HNS PF00816.16 EIE82936.1 - 0.37 11.3 6.7 0.55 10.7 0.1 2.7 3 0 0 3 3 3 0 H-NS histone family Glyco_hydro_47 PF01532.15 EIE82937.1 - 5.6e-108 361.4 0.1 2.4e-61 207.7 0.0 3.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 47 STE PF02200.11 EIE82938.1 - 3e-57 191.4 0.3 3.1e-56 188.2 0.1 2.3 2 0 0 2 2 2 1 STE like transcription factor zf-C2H2 PF00096.21 EIE82938.1 - 0.00075 19.6 0.8 0.0024 18.1 0.6 2.0 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EIE82938.1 - 0.0087 15.9 1.4 0.019 14.8 1.0 1.6 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EIE82938.1 - 0.016 15.3 0.4 0.037 14.1 0.3 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Amino_oxidase PF01593.19 EIE82939.1 - 1.3e-39 136.5 0.0 8.6e-21 74.5 0.0 3.0 2 1 1 3 3 3 3 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EIE82939.1 - 2.6e-09 36.9 0.2 9e-09 35.2 0.1 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EIE82939.1 - 5.2e-05 23.3 0.1 0.00013 22.1 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EIE82939.1 - 0.0032 17.3 0.0 0.005 16.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EIE82939.1 - 0.018 14.1 0.0 0.031 13.3 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Malic_M PF03949.10 EIE82939.1 - 0.034 13.7 0.0 0.29 10.6 0.0 2.1 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain DAO PF01266.19 EIE82939.1 - 0.046 12.6 0.1 0.083 11.7 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 EIE82939.1 - 0.062 13.7 0.1 0.24 11.8 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIE82939.1 - 0.14 10.5 0.5 0.36 9.2 0.1 1.8 2 0 0 2 2 2 0 HI0933-like protein BCDHK_Adom3 PF10436.4 EIE82940.1 - 9.6e-61 204.0 0.0 1.4e-60 203.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EIE82940.1 - 1.2e-12 47.5 0.0 2.7e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EIE82940.1 - 1.2e-05 24.9 0.0 2.2e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Usp PF00582.21 EIE82942.1 - 0.077 13.1 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 Universal stress protein family Pkinase PF00069.20 EIE82943.1 - 4.3e-38 130.9 0.0 5.3e-38 130.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE82943.1 - 6.3e-21 74.6 0.0 1.1e-20 73.8 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EIE82943.1 - 0.00067 19.0 0.0 0.0057 16.0 0.0 2.0 2 0 0 2 2 2 1 RIO1 family Kinase-like PF14531.1 EIE82943.1 - 0.058 12.3 0.0 0.13 11.1 0.0 1.5 1 1 0 1 1 1 0 Kinase-like YrbL-PhoP_reg PF10707.4 EIE82943.1 - 0.13 11.6 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Atrophin-1 PF03154.10 EIE82944.1 - 5.9 4.8 13.3 7.5 4.5 9.2 1.0 1 0 0 1 1 1 0 Atrophin-1 family Med3 PF11593.3 EIE82944.1 - 8.1 5.5 18.1 12 5.0 12.6 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Vps8 PF12816.2 EIE82946.1 - 3.9e-62 208.9 0.6 6.9e-61 204.9 0.0 3.1 4 0 0 4 4 4 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.15 EIE82946.1 - 2.1e-08 33.8 5.2 0.0014 18.2 0.0 4.6 3 1 0 3 3 3 2 Region in Clathrin and VPS zf-RING_5 PF14634.1 EIE82946.1 - 0.00067 19.3 1.5 0.0015 18.2 1.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 EIE82946.1 - 0.0011 19.0 0.6 0.003 17.6 0.4 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EIE82946.1 - 0.0026 17.5 5.7 0.01 15.6 4.0 2.1 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EIE82946.1 - 0.015 15.3 1.2 0.015 15.3 0.8 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EIE82946.1 - 0.017 14.7 3.6 0.049 13.3 2.5 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Pkinase PF00069.20 EIE82947.1 - 9.5e-67 224.8 0.0 3.6e-66 222.9 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE82947.1 - 3e-48 164.1 0.0 7e-48 162.9 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE82947.1 - 9.1e-08 31.4 0.0 7.3e-05 21.8 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Ras_bdg_2 PF14847.1 EIE82947.1 - 8.3e-07 28.9 0.0 2.3e-06 27.4 0.0 1.8 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_1 PF00536.25 EIE82947.1 - 8.9e-05 22.5 0.0 0.00019 21.5 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EIE82947.1 - 0.00057 19.6 0.0 0.0012 18.6 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Kdo PF06293.9 EIE82947.1 - 0.046 12.7 0.0 0.16 10.9 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Septin PF00735.13 EIE82948.1 - 1.5e-107 358.8 0.0 1.5e-107 358.8 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 EIE82948.1 - 1e-05 25.4 0.0 2.4e-05 24.2 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EIE82948.1 - 0.0049 16.0 0.1 0.017 14.2 0.1 1.9 1 1 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EIE82948.1 - 0.01 15.2 0.1 0.031 13.7 0.0 1.8 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_17 PF13207.1 EIE82948.1 - 0.012 16.3 3.9 0.084 13.7 2.7 2.5 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 EIE82948.1 - 0.014 15.2 4.2 3.2 7.5 0.0 3.1 2 1 1 3 3 3 0 Dynamin family AIG1 PF04548.11 EIE82948.1 - 0.041 12.9 0.0 0.12 11.4 0.0 1.9 2 0 0 2 2 2 0 AIG1 family Miro PF08477.8 EIE82948.1 - 0.064 13.7 0.1 0.2 12.1 0.0 1.9 2 0 0 2 2 2 0 Miro-like protein DUF2971 PF11185.3 EIE82948.1 - 0.18 12.5 2.1 1.4 9.6 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2971) RRM_6 PF14259.1 EIE82949.1 - 1.1e-25 89.3 0.4 2.1e-07 30.8 0.0 4.2 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EIE82949.1 - 1.3e-23 82.4 1.6 5.8e-10 38.6 0.1 3.8 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE82949.1 - 5.8e-15 54.8 3.6 0.00014 21.6 0.0 4.2 5 0 0 5 5 5 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EIE82949.1 - 0.0058 16.4 0.4 0.035 13.9 0.1 2.2 2 0 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.1 EIE82949.1 - 0.017 14.8 0.1 0.23 11.2 0.0 2.7 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif Baculo_LEF-10 PF07206.6 EIE82949.1 - 0.12 12.0 0.1 11 5.7 0.0 2.9 2 1 1 3 3 3 0 Baculovirus late expression factor 10 (LEF-10) Carn_acyltransf PF00755.15 EIE82950.1 - 6e-179 595.9 0.1 7e-179 595.7 0.1 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase DUF3808 PF10300.4 EIE82952.1 - 5.1e-39 134.1 5.3 9.9e-25 87.0 1.6 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3808) TPR_12 PF13424.1 EIE82952.1 - 0.11 12.4 0.3 11 5.9 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat GATA PF00320.22 EIE82954.1 - 2.2e-32 110.0 19.7 2.5e-16 58.6 3.5 2.7 2 0 0 2 2 2 2 GATA zinc finger RRN7 PF11781.3 EIE82954.1 - 1.5e-05 24.4 5.7 0.0069 15.8 0.4 2.5 2 0 0 2 2 2 2 RNA polymerase I-specific transcription initiation factor Rrn7 TF_Zn_Ribbon PF08271.7 EIE82954.1 - 0.0003 20.0 14.4 0.0052 16.0 0.5 3.2 3 0 0 3 3 3 2 TFIIB zinc-binding Zn-ribbon_8 PF09723.5 EIE82954.1 - 0.11 12.4 4.6 6.6 6.7 0.1 3.1 3 0 0 3 3 3 0 Zinc ribbon domain eIF-5_eIF-2B PF01873.12 EIE82954.1 - 0.77 9.4 9.7 0.69 9.5 0.4 3.1 3 0 0 3 3 3 0 Domain found in IF2B/IF5 zf-CHY PF05495.7 EIE82954.1 - 0.93 9.6 9.2 0.66 10.1 2.3 2.6 2 0 0 2 2 2 0 CHY zinc finger NinF PF05810.7 EIE82954.1 - 1.1 9.1 4.3 16 5.3 0.6 3.3 2 0 0 2 2 2 0 NinF protein OrfB_Zn_ribbon PF07282.6 EIE82954.1 - 2 8.1 14.7 0.54 9.9 0.4 3.2 3 1 1 4 4 4 0 Putative transposase DNA-binding domain FBPase PF00316.15 EIE82955.1 - 6.7e-126 419.5 0.0 7.6e-126 419.3 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase DDHD PF02862.12 EIE82956.1 - 3.1e-24 86.0 0.1 1e-23 84.3 0.0 1.9 2 1 0 2 2 2 1 DDHD domain CHB_HEX PF03173.8 EIE82956.1 - 0.016 14.6 0.0 1.9 7.9 0.0 2.4 2 0 0 2 2 2 0 Putative carbohydrate binding domain RVT_1 PF00078.22 EIE82958.1 - 6.9e-09 35.3 0.0 1.2e-08 34.6 0.0 1.4 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_2 PF07727.9 EIE82958.1 - 0.062 12.2 0.0 0.072 12.0 0.0 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EIE82959.1 - 1.1e-12 48.0 0.0 1.6e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain zf-C2H2_2 PF12756.2 EIE82960.1 - 4.2e-06 26.7 1.2 7.9e-06 25.9 0.9 1.4 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 EIE82960.1 - 0.0068 16.6 12.1 0.4 11.1 1.2 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIE82960.1 - 0.28 11.6 15.8 0.12 12.7 2.3 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-Di19 PF05605.7 EIE82960.1 - 0.86 9.7 8.9 0.72 10.0 2.9 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding RVP PF00077.15 EIE82961.1 - 0.0009 19.1 0.3 0.0041 17.0 0.1 2.2 1 1 1 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 EIE82961.1 - 0.0019 18.6 0.1 0.0042 17.5 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.12 EIE82961.1 - 0.022 14.8 0.4 0.12 12.4 0.0 2.4 3 0 0 3 3 3 0 Retrotransposon gag protein Chromo PF00385.19 EIE82962.1 - 6.4e-09 35.3 3.0 6.9e-09 35.2 0.1 2.4 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain BRE1 PF08647.6 EIE82962.1 - 5.7 6.9 12.3 7.5 6.6 7.3 2.1 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Chromo PF00385.19 EIE82963.1 - 1.4e-09 37.4 0.5 3.1e-09 36.3 0.3 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 EIE82963.1 - 0.011 15.4 1.2 0.021 14.5 0.1 2.1 2 0 0 2 2 2 0 RNA binding activity-knot of a chromodomain RVT_1 PF00078.22 EIE82964.1 - 0.0081 15.5 1.3 0.1 11.9 0.9 2.0 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ANP PF00212.13 EIE82964.1 - 0.17 11.9 1.2 0.33 11.0 0.0 1.9 2 0 0 2 2 2 0 Atrial natriuretic peptide rve PF00665.21 EIE82965.1 - 9.3e-14 51.5 0.0 1.4e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Prothymosin PF03247.9 EIE82965.1 - 0.18 11.9 1.7 0.29 11.2 1.2 1.2 1 0 0 1 1 1 0 Prothymosin/parathymosin family MRL1 PF13003.2 EIE82966.1 - 0.0057 16.4 0.1 0.0072 16.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L1 bHLH-MYC_N PF14215.1 EIE82967.1 - 0.058 13.5 0.2 0.079 13.1 0.1 1.4 1 0 0 1 1 1 0 bHLH-MYC and R2R3-MYB transcription factors N-terminal NurA PF09376.5 EIE82967.1 - 0.15 11.5 0.2 0.17 11.3 0.2 1.2 1 0 0 1 1 1 0 NurA domain DUF4119 PF13494.1 EIE82967.1 - 0.2 11.6 3.7 0.082 12.8 0.7 1.8 2 0 0 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF4119) PRKCSH PF07915.8 EIE82967.1 - 5.6 7.8 8.8 2.1 9.2 1.0 2.4 1 1 1 2 2 2 0 Glucosidase II beta subunit-like protein DDE_3 PF13358.1 EIE82968.1 - 9.5e-19 67.5 0.1 1.8e-18 66.7 0.1 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE82968.1 - 1.2e-06 28.4 0.5 1.2e-06 28.4 0.3 2.4 1 1 1 2 2 2 1 Transposase HTH_29 PF13551.1 EIE82968.1 - 0.0012 18.9 1.6 0.0034 17.4 1.1 1.9 1 1 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_ISL3 PF13542.1 EIE82968.1 - 0.039 13.1 0.6 0.039 13.1 0.4 2.4 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 HTH_32 PF13565.1 EIE82968.1 - 0.046 14.5 0.7 0.28 12.0 0.5 2.4 2 0 0 2 2 2 0 Homeodomain-like domain rve PF00665.21 EIE82968.1 - 0.06 13.4 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain HTH_12 PF08461.5 EIE82968.1 - 0.11 12.2 0.0 0.35 10.6 0.0 1.8 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain DUF1033 PF06279.6 EIE82968.1 - 0.22 11.3 0.0 0.22 11.3 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1033) HTH_23 PF13384.1 EIE82968.1 - 0.44 10.2 2.9 3.8 7.2 0.2 2.6 2 0 0 2 2 2 0 Homeodomain-like domain HTH_21 PF13276.1 EIE82968.1 - 0.93 9.5 4.3 1.5 8.8 0.0 2.8 3 0 0 3 3 3 0 HTH-like domain DDE_Tnp_IS1595 PF12762.2 EIE82969.1 - 2.9e-06 27.1 0.1 5.3e-06 26.3 0.1 1.4 1 0 0 1 1 1 1 ISXO2-like transposase domain NOA36 PF06524.7 EIE82970.1 - 1.8 7.7 7.8 3.5 6.7 5.4 1.5 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.7 EIE82970.1 - 2 8.0 15.7 0.1 12.2 6.1 1.9 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Daxx PF03344.10 EIE82970.1 - 8.3 4.7 19.4 8.2 4.7 13.5 1.2 1 1 0 1 1 1 0 Daxx Family DDE_Tnp_IS1595 PF12762.2 EIE82971.1 - 8e-23 80.9 0.6 1.5e-22 80.0 0.2 1.6 2 0 0 2 2 2 1 ISXO2-like transposase domain Asp_protease_2 PF13650.1 EIE82972.1 - 2.3e-05 24.7 0.0 4.9e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EIE82972.1 - 6.2e-05 22.7 0.0 0.00012 21.8 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.5 EIE82972.1 - 0.00025 20.6 0.1 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 EIE82972.1 - 0.018 14.9 0.1 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease DDE_Tnp_IS1595 PF12762.2 EIE82973.1 - 8e-23 80.9 0.6 1.5e-22 80.0 0.2 1.6 2 0 0 2 2 2 1 ISXO2-like transposase domain DDE_3 PF13358.1 EIE82976.1 - 3.6e-12 46.2 0.2 4.7e-12 45.8 0.2 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease RVT_1 PF00078.22 EIE82977.1 - 1.9e-23 82.9 0.6 4.3e-23 81.8 0.4 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP PF00077.15 EIE82977.1 - 5e-07 29.5 0.0 1.2e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EIE82977.1 - 5.5e-06 26.0 0.0 1.3e-05 24.8 0.0 1.7 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EIE82977.1 - 8.4e-06 26.2 0.0 1.6e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.6 EIE82977.1 - 0.0018 18.2 0.0 0.0039 17.1 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 EIE82977.1 - 0.057 12.9 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease DDE_3 PF13358.1 EIE82978.1 - 1.5e-17 63.7 0.4 5e-17 62.0 0.0 2.0 3 0 0 3 3 3 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE82978.1 - 1.8e-10 40.7 0.4 4.2e-10 39.5 0.2 1.7 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.1 EIE82978.1 - 0.042 13.9 0.0 0.12 12.5 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn helix Retrotrans_gag PF03732.12 EIE82979.1 - 8e-16 57.8 0.5 1.3e-15 57.1 0.4 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein DDE_3 PF13358.1 EIE82980.1 - 1.5e-18 66.9 0.0 2.3e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE82980.1 - 7.4e-06 25.9 0.6 2.9e-05 24.0 0.7 1.8 2 0 0 2 2 2 1 Transposase Transposase_21 PF02992.9 EIE82981.1 - 5.8e-23 81.1 0.1 5.8e-23 81.1 0.1 1.7 2 0 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.1 EIE82981.1 - 3.9e-05 23.0 0.3 8.6e-05 21.9 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Lzipper-MIP1 PF14389.1 EIE82982.1 - 0.0047 17.0 0.4 0.013 15.6 0.3 1.7 1 0 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 ChaB PF06150.7 EIE82982.1 - 0.078 12.7 0.1 0.25 11.1 0.1 1.8 1 0 0 1 1 1 0 ChaB DUF4367 PF14285.1 EIE82982.1 - 0.14 11.4 3.9 0.23 10.7 2.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4367) IncA PF04156.9 EIE82982.1 - 0.19 11.3 1.5 0.31 10.6 1.0 1.4 1 0 0 1 1 1 0 IncA protein DUF4404 PF14357.1 EIE82982.1 - 0.21 12.0 2.2 9.3 6.7 0.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) HTH_Tnp_Tc3_2 PF01498.13 EIE82983.1 - 4.7e-19 68.2 0.8 4.7e-19 68.2 0.6 2.2 3 0 0 3 3 3 1 Transposase DDE_3 PF13358.1 EIE82983.1 - 6.8e-18 64.8 0.4 1.7e-17 63.4 0.2 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_29 PF13551.1 EIE82983.1 - 5.3e-07 29.7 0.9 1.5e-06 28.3 0.3 2.0 2 0 0 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.1 EIE82983.1 - 8.7e-05 22.0 0.5 0.0049 16.4 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_32 PF13565.1 EIE82983.1 - 0.0027 18.4 6.6 0.0061 17.3 0.0 4.0 4 1 1 5 5 5 1 Homeodomain-like domain HTH_28 PF13518.1 EIE82983.1 - 0.021 14.7 0.0 0.074 13.0 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain Ku_PK_bind PF08785.6 EIE82983.1 - 0.067 13.0 0.0 0.19 11.6 0.0 1.8 1 0 0 1 1 1 0 Ku C terminal domain like Trp_repressor PF01371.14 EIE82983.1 - 0.083 12.8 0.1 0.65 9.9 0.0 2.2 2 0 0 2 2 2 0 Trp repressor protein HTH_40 PF14493.1 EIE82983.1 - 0.089 13.0 0.6 0.95 9.7 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain DDE_3 PF13358.1 EIE82984.1 - 2e-13 50.3 0.0 3.1e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EIE82985.1 - 8.5e-15 54.7 0.1 1.5e-14 53.9 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE82985.1 - 3.7e-14 52.5 0.3 1.1e-13 50.9 0.2 1.9 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.1 EIE82985.1 - 2e-05 24.7 0.3 4.2e-05 23.6 0.2 1.6 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EIE82985.1 - 0.00031 20.2 0.1 0.0026 17.3 0.0 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_7 PF02796.10 EIE82985.1 - 0.00041 20.1 0.4 0.07 12.9 0.1 2.8 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase Transposase_21 PF02992.9 EIE82986.1 - 2.3e-22 79.2 0.0 3.5e-22 78.6 0.0 1.2 1 0 0 1 1 1 1 Transposase family tnp2 DUF1258 PF06869.7 EIE82986.1 - 0.0021 17.1 0.0 0.0034 16.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) FKBP_N PF01346.13 EIE82987.1 - 0.012 15.6 1.5 0.012 15.6 1.1 2.3 3 0 0 3 3 3 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase LAG1-DNAbind PF09271.6 EIE82987.1 - 0.07 13.6 0.3 0.07 13.6 0.2 1.6 2 0 0 2 2 2 0 LAG1, DNA binding YebO PF13974.1 EIE82987.1 - 0.9 9.3 7.5 9.7 6.0 0.0 2.5 2 0 0 2 2 2 0 YebO-like protein HTH_37 PF13744.1 EIE82987.1 - 1.6 8.6 6.6 20 5.1 3.3 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain Transposase_21 PF02992.9 EIE82988.1 - 7.9e-22 77.4 0.0 1.5e-21 76.5 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 DUF1258 PF06869.7 EIE82988.1 - 0.0033 16.5 0.6 0.0048 16.0 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1258) RVT_1 PF00078.22 EIE82990.1 - 8.7e-22 77.5 0.1 1.5e-21 76.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.12 EIE82990.1 - 7.4e-08 32.3 0.2 1.8e-07 31.1 0.2 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein Asp_protease_2 PF13650.1 EIE82990.1 - 8.7e-08 32.5 0.1 3.3e-07 30.7 0.1 2.0 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EIE82990.1 - 6.6e-06 25.8 0.1 1.9e-05 24.3 0.1 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.18 EIE82990.1 - 0.00084 19.1 1.0 0.0015 18.3 0.7 1.5 1 0 0 1 1 1 1 Zinc knuckle Autophagy_N PF03986.8 EIE82990.1 - 0.022 14.5 0.3 0.045 13.5 0.2 1.4 1 0 0 1 1 1 0 Autophagocytosis associated protein (Atg3), N-terminal domain RVP PF00077.15 EIE82990.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Med15 PF09606.5 EIE82991.1 - 0.028 12.6 12.5 0.04 12.1 8.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal FlgM PF04316.8 EIE82991.1 - 0.51 10.3 5.1 13 5.8 2.9 2.4 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM Transposase_21 PF02992.9 EIE82993.1 - 4.2e-22 78.3 0.0 9.1e-22 77.2 0.0 1.5 1 0 0 1 1 1 1 Transposase family tnp2 DUF1258 PF06869.7 EIE82993.1 - 0.0017 17.5 0.0 0.0027 16.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) PIF1 PF05970.9 EIE82995.1 - 5.3e-81 272.3 0.0 7.5e-81 271.8 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.1 EIE82995.1 - 1.1e-65 220.7 0.0 2.9e-65 219.4 0.0 1.7 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.1 EIE82995.1 - 8.5e-06 25.4 0.0 3e-05 23.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 EIE82995.1 - 0.00029 20.7 0.0 0.00081 19.2 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EIE82995.1 - 0.00045 19.9 0.0 0.00092 18.9 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 EIE82995.1 - 0.0048 16.6 0.0 0.016 14.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EIE82995.1 - 0.03 14.3 0.0 0.17 11.8 0.0 2.2 3 0 0 3 3 3 0 AAA ATPase domain TrwB_AAD_bind PF10412.4 EIE82995.1 - 0.033 12.8 0.0 0.055 12.0 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain T2SE PF00437.15 EIE82995.1 - 0.034 13.0 0.0 0.058 12.2 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.11 EIE82995.1 - 0.055 12.7 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein DAP3 PF10236.4 EIE82995.1 - 0.068 12.0 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_10 PF12846.2 EIE82995.1 - 0.12 11.8 0.1 1.2 8.4 0.0 2.4 2 1 0 2 2 2 0 AAA-like domain GFA PF04828.9 EIE82996.1 - 0.0092 15.9 0.8 0.0092 15.9 0.5 2.0 1 1 1 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.2 EIE82996.1 - 0.014 15.2 7.7 0.18 11.6 5.3 2.2 1 1 0 1 1 1 0 Double zinc ribbon A2L_zn_ribbon PF08792.5 EIE82996.1 - 0.022 14.2 2.9 14 5.2 0.0 3.1 3 0 0 3 3 3 0 A2L zinc ribbon domain zf-C4pol PF14260.1 EIE82996.1 - 0.033 14.1 4.5 0.45 10.5 3.1 2.0 1 1 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta zf-piccolo PF05715.8 EIE82996.1 - 0.33 10.9 3.5 1.1 9.3 0.9 2.2 2 0 0 2 2 2 0 Piccolo Zn-finger HypA PF01155.14 EIE82996.1 - 0.37 10.4 4.9 1.7 8.3 1.4 2.0 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family RRN7 PF11781.3 EIE82996.1 - 0.71 9.4 7.9 5.8 6.5 0.3 3.2 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-ribbon_3 PF13248.1 EIE82996.1 - 1.4 8.2 8.1 0.57 9.4 1.9 2.5 1 1 1 2 2 2 0 zinc-ribbon domain Spt4 PF06093.8 EIE82996.1 - 2 8.3 5.4 2 8.3 1.0 2.1 1 1 1 2 2 2 0 Spt4/RpoE2 zinc finger DUF2039 PF10217.4 EIE82996.1 - 2.3 8.3 6.8 18 5.4 0.1 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2039) zinc_ribbon_2 PF13240.1 EIE82996.1 - 3.5 7.2 8.4 3.8 7.1 0.1 2.8 2 1 0 2 2 2 0 zinc-ribbon domain DDE_3 PF13358.1 EIE82997.1 - 1.6e-17 63.6 0.1 2.7e-17 62.8 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE82997.1 - 1.1e-10 41.3 0.8 2.2e-10 40.4 0.3 1.7 2 0 0 2 2 2 1 Transposase HTH_Tnp_Tc3_2 PF01498.13 EIE82999.1 - 5.2e-16 58.4 1.4 3e-15 56.0 0.2 2.2 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 EIE82999.1 - 3e-05 24.1 1.3 4.4e-05 23.5 0.1 1.8 2 0 0 2 2 2 1 Winged helix-turn helix HTH_38 PF13936.1 EIE82999.1 - 3.3e-05 23.3 0.0 0.00051 19.5 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.1 EIE82999.1 - 0.00046 19.7 0.0 0.02 14.5 0.0 2.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.1 EIE82999.1 - 0.001 19.8 5.1 0.14 13.0 0.1 3.1 2 1 1 3 3 3 1 Homeodomain-like domain HTH_21 PF13276.1 EIE82999.1 - 0.0012 18.7 0.0 0.17 11.9 0.0 2.5 2 0 0 2 2 2 1 HTH-like domain HTH_28 PF13518.1 EIE82999.1 - 0.0029 17.5 0.0 0.017 15.1 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_7 PF02796.10 EIE82999.1 - 0.003 17.3 1.1 0.3 10.9 0.1 2.7 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase ABC_ATPase PF09818.4 EIE82999.1 - 0.056 12.0 0.0 0.069 11.7 0.0 1.1 1 0 0 1 1 1 0 Predicted ATPase of the ABC class DUF2857 PF11198.3 EIE82999.1 - 0.057 12.9 0.0 0.091 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2857) CPSase_L_D3 PF02787.14 EIE82999.1 - 0.086 12.6 0.0 0.34 10.6 0.0 1.8 2 0 0 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain Sigma70_r4_2 PF08281.7 EIE82999.1 - 0.19 11.1 0.8 1.2 8.6 0.0 2.5 3 1 0 3 3 3 0 Sigma-70, region 4 DDE_3 PF13358.1 EIE83000.1 - 3e-17 62.7 0.1 5.9e-17 61.7 0.1 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE83000.1 - 9.8e-12 44.7 2.1 1.2e-11 44.5 0.3 2.0 3 0 0 3 3 3 1 Transposase HTH_29 PF13551.1 EIE83000.1 - 0.0041 17.2 0.3 0.013 15.6 0.0 1.9 2 0 0 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.1 EIE83000.1 - 0.008 15.8 0.0 0.02 14.5 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain DDE_3 PF13358.1 EIE83001.1 - 8.4e-15 54.7 0.5 1.4e-14 54.0 0.3 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE83001.1 - 0.024 14.7 0.0 0.038 14.1 0.0 1.3 1 0 0 1 1 1 0 Integrase core domain zf-trcl PF13451.1 EIE83001.1 - 0.096 12.3 0.5 0.25 11.0 0.3 1.7 1 0 0 1 1 1 0 Probable zinc-binding domain DDE_3 PF13358.1 EIE83002.1 - 1.2e-14 54.2 0.1 2.4e-14 53.2 0.1 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE83002.1 - 8.3e-14 51.4 1.3 1.5e-13 50.5 0.2 2.1 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 EIE83002.1 - 2.8e-05 24.2 0.3 5.7e-05 23.2 0.2 1.6 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EIE83002.1 - 0.00053 19.5 0.4 0.0032 17.0 0.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_7 PF02796.10 EIE83002.1 - 0.00056 19.7 0.6 0.071 12.9 0.1 2.8 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase Leader_Erm PF08253.6 EIE83003.1 - 0.33 10.4 0.3 0.33 10.4 0.2 2.1 2 0 0 2 2 2 0 Erm Leader peptide DivIVA PF05103.8 EIE83004.1 - 0.00012 22.1 0.4 0.00016 21.7 0.3 1.1 1 0 0 1 1 1 1 DivIVA protein DivIC PF04977.10 EIE83004.1 - 0.00018 20.8 1.6 0.00026 20.3 0.9 1.4 2 0 0 2 2 2 1 Septum formation initiator bZIP_1 PF00170.16 EIE83004.1 - 0.0041 17.0 1.5 0.0069 16.3 1.0 1.3 1 0 0 1 1 1 1 bZIP transcription factor ADIP PF11559.3 EIE83004.1 - 0.0056 16.6 0.9 0.0072 16.2 0.6 1.2 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding DUF972 PF06156.8 EIE83004.1 - 0.0067 16.7 0.4 0.0077 16.5 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF972) DASH_Spc34 PF08657.5 EIE83004.1 - 0.0077 15.9 0.3 0.0094 15.6 0.2 1.1 1 0 0 1 1 1 1 DASH complex subunit Spc34 MAD PF05557.8 EIE83004.1 - 0.011 13.8 0.4 0.014 13.5 0.3 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein Herpes_UL6 PF01763.11 EIE83004.1 - 0.014 13.5 0.3 0.017 13.3 0.2 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like bZIP_2 PF07716.10 EIE83004.1 - 0.019 14.7 4.0 0.021 14.6 2.2 1.5 1 1 0 1 1 1 0 Basic region leucine zipper ATG16 PF08614.6 EIE83004.1 - 0.02 14.7 0.2 0.025 14.4 0.2 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) BCAS2 PF05700.6 EIE83004.1 - 0.022 14.2 0.1 0.03 13.7 0.1 1.3 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) Ax_dynein_light PF10211.4 EIE83004.1 - 0.027 14.2 0.2 0.032 14.0 0.1 1.2 1 0 0 1 1 1 0 Axonemal dynein light chain TACC PF05010.9 EIE83004.1 - 0.05 13.3 0.2 0.052 13.2 0.2 1.1 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) XhlA PF10779.4 EIE83004.1 - 0.052 13.4 2.3 0.075 12.9 1.6 1.2 1 0 0 1 1 1 0 Haemolysin XhlA TMF_DNA_bd PF12329.3 EIE83004.1 - 0.053 13.3 4.4 0.082 12.7 3.1 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding IncA PF04156.9 EIE83004.1 - 0.053 13.1 0.2 0.063 12.8 0.1 1.1 1 0 0 1 1 1 0 IncA protein Alpha-2-MRAP_C PF06401.6 EIE83004.1 - 0.054 13.3 0.1 0.065 13.0 0.0 1.1 1 0 0 1 1 1 0 Alpha-2-macroglobulin RAP, C-terminal domain DUF904 PF06005.7 EIE83004.1 - 0.054 13.7 0.8 0.065 13.5 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF904) BLOC1_2 PF10046.4 EIE83004.1 - 0.066 13.3 0.8 0.099 12.7 0.6 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Shugoshin_N PF07558.6 EIE83004.1 - 0.071 12.8 1.4 0.17 11.5 0.7 1.8 1 1 1 2 2 2 0 Shugoshin N-terminal coiled-coil region DUF4446 PF14584.1 EIE83004.1 - 0.11 12.3 0.6 0.13 12.1 0.2 1.3 2 0 0 2 2 1 0 Protein of unknown function (DUF4446) DUF4140 PF13600.1 EIE83004.1 - 0.12 12.8 0.7 0.16 12.4 0.5 1.1 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF2630 PF10944.3 EIE83004.1 - 0.15 12.1 1.8 0.24 11.5 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2630) NEMO PF11577.3 EIE83004.1 - 0.17 11.6 1.7 0.27 11.0 1.1 1.3 1 0 0 1 1 1 0 NF-kappa-B essential modulator NEMO DUF3972 PF13118.1 EIE83004.1 - 0.23 11.5 2.6 0.24 11.4 1.2 1.4 2 0 0 2 2 1 0 Protein of unknown function (DUF3972) HTH_Tnp_Tc3_2 PF01498.13 EIE83005.1 - 6e-07 29.4 0.4 4.1e-06 26.7 0.1 2.2 2 0 0 2 2 2 1 Transposase HTH_Tnp_ISL3 PF13542.1 EIE83005.1 - 0.0013 17.8 0.1 0.0042 16.2 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_23 PF13384.1 EIE83005.1 - 0.0034 17.0 0.0 0.044 13.4 0.0 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.1 EIE83005.1 - 0.015 16.0 0.5 7.3 7.4 0.0 2.8 1 1 2 3 3 3 0 Homeodomain-like domain HTH_28 PF13518.1 EIE83005.1 - 0.043 13.8 0.0 0.11 12.4 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_IclR PF09339.5 EIE83005.1 - 0.059 12.9 0.1 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_Tnp_1 PF01527.15 EIE83005.1 - 0.076 12.9 0.0 11 6.0 0.0 2.5 2 0 0 2 2 2 0 Transposase DUF4218 PF13960.1 EIE83007.1 - 6.5e-07 28.8 0.0 1.2e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) HTH_Tnp_Tc3_2 PF01498.13 EIE83008.1 - 1.1e-07 31.8 0.1 1.2e-07 31.6 0.1 1.1 1 0 0 1 1 1 1 Transposase Transposase_21 PF02992.9 EIE83009.1 - 6.6e-19 67.9 1.0 7.1e-19 67.8 0.0 1.5 2 0 0 2 2 2 1 Transposase family tnp2 Rpr2 PF04032.11 EIE83009.1 - 0.059 13.2 1.3 2.8 7.8 0.1 2.7 1 1 1 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Leader_Erm PF08253.6 EIE83010.1 - 0.33 10.4 0.3 0.33 10.4 0.2 2.0 2 0 0 2 2 2 0 Erm Leader peptide DUF569 PF04601.8 EIE83011.1 - 0.0046 16.4 0.1 0.017 14.5 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF569) DUF569 PF04601.8 EIE83014.1 - 0.02 14.2 0.0 0.023 14.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF569) HTH_12 PF08461.5 EIE83014.1 - 0.022 14.4 0.0 0.046 13.4 0.0 1.5 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain Med15 PF09606.5 EIE83015.1 - 0.042 12.0 13.1 0.062 11.4 9.1 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal FlgM PF04316.8 EIE83015.1 - 2.3 8.2 5.1 13 5.8 2.9 2.2 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM Transposase_21 PF02992.9 EIE83016.1 - 2.4e-21 75.8 0.0 5.8e-21 74.6 0.0 1.6 1 0 0 1 1 1 1 Transposase family tnp2 DUF1258 PF06869.7 EIE83016.1 - 0.0023 17.0 0.0 0.0038 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) DDE_3 PF13358.1 EIE83018.1 - 4.3e-21 75.2 0.4 5.9e-21 74.7 0.3 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EIE83020.1 - 3.2e-12 46.4 0.2 4.3e-12 46.0 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1759 PF03564.10 EIE83021.1 - 0.00052 19.8 0.4 0.00052 19.8 0.3 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1759) HTH_Tnp_Tc3_2 PF01498.13 EIE83022.1 - 0.00061 19.7 0.2 0.00088 19.2 0.1 1.3 1 0 0 1 1 1 1 Transposase rve PF00665.21 EIE83023.1 - 1.6e-20 73.3 0.0 5.1e-20 71.7 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE83023.1 - 9.9e-11 41.3 0.2 2.3e-10 40.1 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE83023.1 - 1.4e-10 40.6 0.4 3.6e-10 39.3 0.3 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.12 EIE83024.1 - 6.5e-05 22.9 0.8 0.00014 21.8 0.1 1.9 2 0 0 2 2 2 1 Retrotransposon gag protein UBN2_2 PF14227.1 EIE83024.1 - 0.059 12.9 0.2 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Chromate_transp PF02417.10 EIE83025.1 - 0.12 12.0 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 Chromate transporter MRL1 PF13003.2 EIE83028.1 - 0.0057 16.4 0.1 0.0072 16.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L1 V_ATPase_I PF01496.14 EIE83029.1 - 0.17 9.7 0.1 0.26 9.1 0.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF904 PF06005.7 EIE83029.1 - 0.37 11.1 3.0 2.2 8.6 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF904) bZIP_1 PF00170.16 EIE83029.1 - 0.82 9.6 4.7 0.25 11.3 0.5 2.1 2 0 0 2 2 2 0 bZIP transcription factor HALZ PF02183.13 EIE83029.1 - 1.4 8.6 5.2 0.33 10.6 1.2 1.8 2 0 0 2 2 2 0 Homeobox associated leucine zipper RVT_1 PF00078.22 EIE83030.1 - 5.2e-22 78.2 0.0 8.2e-22 77.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EIE83030.1 - 2.5e-05 23.8 0.0 7e-05 22.4 0.0 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase TPR_MLP1_2 PF07926.7 EIE83031.1 - 0.00012 21.8 0.1 0.00016 21.3 0.1 1.2 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein Paramyx_P_V_C PF03210.8 EIE83031.1 - 0.0045 16.8 0.1 0.008 16.0 0.1 1.5 1 0 0 1 1 1 1 Paramyxovirus P/V phosphoprotein C-terminal DUF972 PF06156.8 EIE83031.1 - 0.049 13.9 0.3 0.08 13.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Phage_GP20 PF06810.6 EIE83031.1 - 0.072 12.5 0.1 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 Reo_sigmaC PF04582.7 EIE83031.1 - 0.12 11.5 4.6 0.16 11.0 3.2 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DivIC PF04977.10 EIE83031.1 - 0.12 11.9 0.2 0.21 11.0 0.1 1.4 1 0 0 1 1 1 0 Septum formation initiator DUF4200 PF13863.1 EIE83031.1 - 0.16 11.9 0.1 0.25 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) bZIP_2 PF07716.10 EIE83031.1 - 0.2 11.4 2.7 1.6 8.6 0.1 2.4 1 1 1 2 2 2 0 Basic region leucine zipper RHIM PF12721.2 EIE83031.1 - 3.5 8.1 7.5 0.44 11.0 1.6 2.2 2 0 0 2 2 2 0 RIP homotypic interaction motif Transposase_21 PF02992.9 EIE83032.1 - 1.3e-16 60.3 0.0 2.2e-16 59.6 0.0 1.4 2 0 0 2 2 2 1 Transposase family tnp2 DUF1258 PF06869.7 EIE83032.1 - 0.0012 18.0 0.0 0.0016 17.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) Med15 PF09606.5 EIE83033.1 - 0.0094 14.2 16.3 0.013 13.6 11.3 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal STIL_N PF15253.1 EIE83033.1 - 0.017 13.8 3.7 0.62 8.7 0.0 2.3 2 0 0 2 2 2 0 SCL-interrupting locus protein N-terminus TFIIA PF03153.8 EIE83033.1 - 0.042 13.7 7.1 0.053 13.4 4.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FlgM PF04316.8 EIE83033.1 - 2.1 8.3 7.5 46 4.0 4.6 2.4 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM DDE_3 PF13358.1 EIE83034.1 - 8.9e-12 44.9 0.1 1.4e-11 44.3 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE83034.1 - 2e-09 37.3 1.0 4.4e-09 36.2 0.4 1.8 2 0 0 2 2 2 1 Transposase rve PF00665.21 EIE83035.1 - 5.6e-24 84.5 0.0 2.1e-23 82.6 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.19 EIE83035.1 - 1.7e-07 30.8 0.4 2.6e-06 26.9 0.0 3.0 3 0 0 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.12 EIE83035.1 - 1.9e-06 27.8 3.8 2.2e-06 27.6 0.1 3.0 2 0 0 2 2 2 1 Retrotransposon gag protein rve_3 PF13683.1 EIE83035.1 - 0.0058 16.1 0.1 0.024 14.1 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain Rtf2 PF04641.7 EIE83038.1 - 4.7e-66 222.6 8.5 6.3e-66 222.2 5.9 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.3 EIE83038.1 - 0.0067 15.9 0.1 0.27 10.7 0.0 2.5 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit YhfH PF14149.1 EIE83038.1 - 0.041 13.6 0.3 0.12 12.1 0.2 1.8 1 0 0 1 1 1 0 YhfH-like protein NARP1 PF12569.3 EIE83038.1 - 0.1 11.3 11.5 0.15 10.8 8.0 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 OmpH PF03938.9 EIE83038.1 - 1.1 9.1 10.6 4.3 7.2 7.3 1.8 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Chitin_synth_2 PF03142.10 EIE83041.1 - 1.3e-86 291.1 5.1 1.5e-86 290.9 3.6 1.0 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 EIE83041.1 - 3.6e-05 23.5 7.4 9.4e-05 22.2 5.2 1.7 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EIE83041.1 - 0.014 15.2 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 DnaJ PF00226.26 EIE83042.1 - 1.4e-22 79.2 1.8 1.4e-22 79.2 1.3 2.4 2 0 0 2 2 2 1 DnaJ domain DUF3395 PF11875.3 EIE83042.1 - 3.6e-18 65.6 4.2 3.6e-18 65.6 2.9 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF3395) MutS_IV PF05190.13 EIE83044.1 - 0.085 13.0 0.1 0.14 12.3 0.1 1.4 1 0 0 1 1 1 0 MutS family domain IV HMG_box PF00505.14 EIE83046.1 - 2.8e-26 91.5 2.7 4.9e-26 90.7 1.8 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EIE83046.1 - 4.5e-19 68.5 2.3 4.5e-19 68.5 1.6 1.5 1 1 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.1 EIE83046.1 - 0.00019 21.1 1.5 0.00019 21.1 1.0 1.9 2 0 0 2 2 2 1 HMG (high mobility group) box 5 CHDNT PF08073.7 EIE83046.1 - 0.002 17.8 0.0 0.0036 16.9 0.0 1.4 1 0 0 1 1 1 1 CHDNT (NUC034) domain DUF1014 PF06244.7 EIE83046.1 - 0.087 13.0 2.3 0.099 12.8 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1014) Btz PF09405.5 EIE83046.1 - 0.18 11.8 6.4 0.3 11.1 4.4 1.4 1 1 0 1 1 1 0 CASC3/Barentsz eIF4AIII binding Apc1 PF12859.2 EIE83047.1 - 4e-12 46.2 0.1 1.1e-11 44.8 0.0 1.9 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.17 EIE83047.1 - 7.1e-11 41.7 4.6 0.033 14.4 0.0 6.0 5 0 0 5 5 5 4 Proteasome/cyclosome repeat DehI PF10778.4 EIE83047.1 - 0.071 12.6 0.1 27 4.2 0.0 3.3 3 0 0 3 3 3 0 Halocarboxylic acid dehydrogenase DehI Cytochrom_C1 PF02167.10 EIE83048.1 - 1.8e-09 37.5 0.0 4.4e-09 36.3 0.0 1.6 1 1 1 2 2 2 1 Cytochrome C1 family Strep_his_triad PF04270.8 EIE83048.1 - 0.005 16.5 1.1 0.011 15.4 0.3 1.8 2 0 0 2 2 2 1 Streptococcal histidine triad protein RNA_pol_N PF01194.12 EIE83049.1 - 3.9e-31 106.8 0.3 4.5e-31 106.6 0.2 1.0 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit WD40 PF00400.27 EIE83050.1 - 2.6e-05 23.9 0.3 0.0022 17.7 0.1 2.1 2 0 0 2 2 2 2 WD domain, G-beta repeat DUF663 PF04950.7 EIE83051.1 - 1.5e-59 201.4 0.0 3.5e-59 200.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EIE83051.1 - 4.1e-24 83.9 0.0 1.3e-23 82.2 0.0 1.9 2 0 0 2 2 2 1 AARP2CN (NUC121) domain Biopterin_H PF00351.16 EIE83052.1 - 1.2e-163 543.5 0.1 1.5e-163 543.2 0.1 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase ACT PF01842.20 EIE83052.1 - 0.005 16.2 0.0 0.01 15.2 0.0 1.5 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.1 EIE83052.1 - 0.027 14.7 0.2 0.062 13.6 0.0 1.7 2 0 0 2 2 2 0 ACT domain CCDC32 PF14989.1 EIE83054.1 - 0.0058 16.4 0.4 0.01 15.6 0.3 1.4 1 1 0 1 1 1 1 Coiled-coil domain containing 32 DUF4468 PF14730.1 EIE83054.1 - 0.046 13.4 0.8 0.08 12.6 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4468) with TBP-like fold Syntaxin PF00804.20 EIE83054.1 - 0.06 13.5 0.5 1.2 9.3 0.0 2.2 2 0 0 2 2 2 0 Syntaxin VWD PF00094.20 EIE83056.1 - 0.16 12.1 4.0 0.05 13.7 0.5 1.8 2 0 0 2 2 2 0 von Willebrand factor type D domain IncA PF04156.9 EIE83056.1 - 2.5 7.6 13.9 0.28 10.7 5.7 2.0 2 0 0 2 2 2 0 IncA protein DUF342 PF03961.8 EIE83056.1 - 3.3 6.0 17.2 0.21 9.9 8.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF342) ADH_N PF08240.7 EIE83057.1 - 2.8e-25 88.1 4.9 4.4e-25 87.5 3.4 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIE83057.1 - 8.5e-18 64.1 0.0 1.2e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EIE83057.1 - 0.00017 20.7 0.0 0.00032 19.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain KOW PF00467.24 EIE83058.1 - 9.3e-11 41.0 2.7 9.3e-11 41.0 1.9 1.7 2 0 0 2 2 2 1 KOW motif DUF1442 PF07279.6 EIE83058.1 - 0.052 12.6 1.0 0.065 12.3 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1442) AA_permease_2 PF13520.1 EIE83060.1 - 7.3e-28 97.2 18.6 1.3e-27 96.4 12.9 1.4 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EIE83060.1 - 3.4e-13 48.7 11.4 4.9e-13 48.2 7.9 1.1 1 0 0 1 1 1 1 Amino acid permease Na_Ca_ex PF01699.19 EIE83060.1 - 8.7 5.9 16.6 20 4.8 7.9 2.9 2 1 1 3 3 3 0 Sodium/calcium exchanger protein Metallophos PF00149.23 EIE83062.1 - 2.3e-22 79.4 1.3 4.6e-22 78.4 0.9 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.1 EIE83062.1 - 2.6e-08 33.8 0.2 1.3e-07 31.5 0.0 2.2 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C Metallophos_2 PF12850.2 EIE83062.1 - 0.00055 19.8 0.7 0.0013 18.6 0.5 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PhoD PF09423.5 EIE83062.1 - 0.0009 17.9 1.0 0.0013 17.3 0.7 1.2 1 0 0 1 1 1 1 PhoD-like phosphatase Adaptin_N PF01602.15 EIE83063.1 - 5e-80 269.3 9.8 4.5e-79 266.1 6.8 2.0 1 1 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 EIE83063.1 - 2.6e-07 30.8 0.0 0.0009 19.4 0.0 4.1 3 2 2 5 5 5 3 HEAT repeats Cnd1 PF12717.2 EIE83063.1 - 2.8e-07 30.5 1.2 2e-05 24.4 0.0 3.1 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 EIE83063.1 - 2.2e-05 24.1 0.7 1.1 9.4 0.0 5.4 5 0 0 5 5 5 1 HEAT repeat BLVR PF06375.6 EIE83063.1 - 2.7e-05 24.0 0.6 2.7e-05 24.0 0.4 4.3 1 1 3 4 4 4 2 Bovine leukaemia virus receptor (BLVR) MFS_1 PF07690.11 EIE83064.1 - 1.6e-07 30.4 15.7 3.2e-07 29.4 11.0 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily HMG_box PF00505.14 EIE83064.1 - 0.048 13.9 0.6 0.092 13.0 0.4 1.4 1 0 0 1 1 1 0 HMG (high mobility group) box HMG_box_2 PF09011.5 EIE83064.1 - 0.079 13.3 0.5 0.15 12.4 0.4 1.4 1 0 0 1 1 1 0 HMG-box domain FA_FANCE PF11510.3 EIE83065.1 - 4e-12 45.8 5.9 7e-10 38.4 1.2 2.3 2 1 0 2 2 2 2 Fanconi Anaemia group E protein FANCE SAP18 PF06487.7 EIE83065.1 - 0.07 12.9 0.1 0.23 11.2 0.0 1.9 2 0 0 2 2 2 0 Sin3 associated polypeptide p18 (SAP18) UPF0139 PF03669.8 EIE83066.1 - 1.3e-10 40.6 0.1 1.7e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) Paf1 PF03985.8 EIE83067.1 - 1.3e-38 132.8 0.0 1.5e-38 132.7 0.0 1.0 1 0 0 1 1 1 1 Paf1 GLYCAM-1 PF05242.6 EIE83067.1 - 0.096 12.6 0.2 0.15 12.0 0.1 1.3 1 0 0 1 1 1 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) ACOX PF01756.14 EIE83068.1 - 8.2e-40 136.1 0.3 5.8e-39 133.4 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 EIE83068.1 - 1e-26 93.6 0.2 2.1e-26 92.6 0.1 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 EIE83068.1 - 3.3e-10 39.3 0.4 8.1e-10 38.0 0.1 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 EIE83068.1 - 1.7e-05 24.9 0.4 0.00038 20.5 0.0 2.6 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EIE83068.1 - 0.0016 18.9 0.1 0.023 15.2 0.0 2.8 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain p450 PF00067.17 EIE83069.1 - 1.8e-63 214.6 3.6 5.3e-63 213.1 2.5 1.6 1 1 0 1 1 1 1 Cytochrome P450 Sec2p PF06428.6 EIE83070.1 - 0.00064 19.5 5.8 0.00064 19.5 4.0 2.5 3 0 0 3 3 3 1 GDP/GTP exchange factor Sec2p GPI-anchored PF10342.4 EIE83071.1 - 1.4e-15 57.5 2.3 1.4e-15 57.5 1.6 1.8 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4614 PF15391.1 EIE83071.1 - 0.19 11.4 7.0 0.28 10.9 4.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) PAP1 PF08601.5 EIE83071.1 - 0.48 10.0 12.7 0.53 9.9 8.8 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Pex14_N PF04695.8 EIE83071.1 - 1.3 9.0 10.7 2.9 7.9 7.4 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Macoilin PF09726.4 EIE83071.1 - 3.4 5.8 16.1 3.8 5.6 11.1 1.0 1 0 0 1 1 1 0 Transmembrane protein Pol_alpha_B_N PF08418.5 EIE83071.1 - 8.6 5.8 13.6 13 5.2 9.4 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal DNA_pol_A_exo1 PF01612.15 EIE83072.1 - 1e-10 41.3 0.2 2e-10 40.3 0.2 1.5 1 0 0 1 1 1 1 3'-5' exonuclease Methyltransf_11 PF08241.7 EIE83073.1 - 5.2e-10 39.6 0.0 1.9e-09 37.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIE83073.1 - 1.1e-06 28.4 0.0 3.3e-06 26.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIE83073.1 - 3.1e-06 26.8 0.0 9.6e-06 25.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIE83073.1 - 0.00018 21.9 0.0 0.012 16.1 0.0 3.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_8 PF05148.10 EIE83073.1 - 0.00035 20.2 0.2 0.00074 19.2 0.1 1.5 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_18 PF12847.2 EIE83073.1 - 0.00049 20.6 0.0 0.0025 18.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIE83073.1 - 0.00073 18.7 0.0 0.004 16.2 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EIE83073.1 - 0.0033 17.7 0.0 0.01 16.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.11 EIE83073.1 - 0.0063 14.9 0.0 0.03 12.6 0.0 1.8 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_4 PF02390.12 EIE83073.1 - 0.0063 15.5 0.0 0.014 14.4 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase DUF3010 PF11215.3 EIE83074.1 - 1.1 9.2 4.7 4.1 7.3 0.0 3.3 2 1 0 3 3 3 0 Protein of unknown function (DUF3010) Sugar_tr PF00083.19 EIE83075.1 - 1.3e-81 274.4 25.5 1.7e-81 274.0 17.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIE83075.1 - 1.3e-27 96.4 60.7 1.2e-25 89.9 21.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EIE83075.1 - 0.0077 14.6 37.0 0.015 13.7 7.3 3.4 2 2 1 3 3 3 2 MFS/sugar transport protein PIGA PF08288.7 EIE83077.1 - 6.5e-33 112.9 1.3 2.8e-32 110.9 0.9 2.0 1 1 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 EIE83077.1 - 1.7e-26 92.6 0.0 3e-26 91.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EIE83077.1 - 2.1e-12 47.0 0.9 3.7e-12 46.3 0.6 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 EIE83077.1 - 9.6e-12 45.3 0.0 1.1e-10 41.8 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.1 EIE83077.1 - 1.7e-11 44.3 0.0 3.1e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 WD40 PF00400.27 EIE83078.1 - 8.1e-29 98.4 2.6 4.7e-06 26.2 0.0 4.4 4 0 0 4 4 4 4 WD domain, G-beta repeat LisH PF08513.6 EIE83078.1 - 8.4e-05 22.1 0.1 0.00026 20.6 0.0 1.9 1 0 0 1 1 1 1 LisH ASF1_hist_chap PF04729.8 EIE83079.1 - 7.4e-67 223.7 0.8 8.6e-67 223.5 0.6 1.0 1 0 0 1 1 1 1 ASF1 like histone chaperone UPF0172 PF03665.8 EIE83079.1 - 0.09 12.2 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) SopA PF13981.1 EIE83080.1 - 0.063 13.2 1.5 0.14 12.2 1.0 1.5 1 0 0 1 1 1 0 SopA-like central domain CCDC-167 PF15188.1 EIE83080.1 - 0.49 10.3 4.8 1.2 9.0 2.2 2.3 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 Uds1 PF15456.1 EIE83080.1 - 0.51 10.3 6.5 0.24 11.3 0.8 2.3 1 1 1 2 2 2 0 Up-regulated During Septation MxiH PF09392.5 EIE83080.1 - 0.78 10.3 5.2 1 9.9 1.9 2.1 2 0 0 2 2 2 0 Type III secretion needle MxiH like Fib_alpha PF08702.5 EIE83080.1 - 0.81 9.8 12.2 0.19 11.8 2.9 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF848 PF05852.6 EIE83080.1 - 5.5 6.8 10.5 2.6 7.8 2.6 2.2 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Thi4 PF01946.12 EIE83081.1 - 1.8e-101 338.0 0.2 2.1e-101 337.8 0.1 1.0 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 EIE83081.1 - 7.9e-12 44.7 0.1 4e-08 32.5 0.1 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EIE83081.1 - 3.9e-07 29.2 0.3 0.00014 20.8 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 EIE83081.1 - 7.7e-07 28.3 0.3 5.5e-06 25.5 0.1 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EIE83081.1 - 6e-06 26.2 0.0 1.5e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EIE83081.1 - 9.6e-06 25.6 0.1 1.5e-05 25.0 0.1 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EIE83081.1 - 0.00011 21.3 0.0 0.00018 20.7 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EIE83081.1 - 0.00015 21.5 0.1 0.0016 18.2 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding GIDA PF01134.17 EIE83081.1 - 0.00025 20.0 0.0 0.26 10.1 0.0 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A HI0933_like PF03486.9 EIE83081.1 - 0.0037 15.7 2.0 0.0075 14.7 0.0 2.2 3 0 0 3 3 3 1 HI0933-like protein GMC_oxred_N PF00732.14 EIE83081.1 - 0.0052 15.9 0.0 1.6 7.7 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase Pyr_redox_3 PF13738.1 EIE83081.1 - 0.017 15.2 0.0 0.032 14.2 0.0 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EIE83081.1 - 0.17 10.8 0.0 0.33 9.8 0.0 1.5 1 1 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) ABC2_membrane PF01061.19 EIE83083.1 - 4.2e-80 267.8 74.7 1.9e-43 148.0 16.2 3.4 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.22 EIE83083.1 - 2.9e-38 131.2 0.0 1.2e-20 74.1 0.0 2.8 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EIE83083.1 - 2.5e-31 107.3 3.0 7.7e-21 73.6 0.0 3.2 2 0 0 2 2 2 2 CDR ABC transporter HTH_Tnp_Tc3_2 PF01498.13 EIE83083.1 - 1.3e-15 57.1 1.1 2.9e-15 56.0 0.8 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.1 EIE83083.1 - 1.8e-15 56.9 0.0 7.3e-15 54.9 0.0 2.1 2 0 0 2 2 2 1 DDE superfamily endonuclease ABC_trans_N PF14510.1 EIE83083.1 - 5.7e-11 42.3 0.0 1.3e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal ABC2_membrane_3 PF12698.2 EIE83083.1 - 1.5e-08 34.1 21.3 1.5e-08 34.1 14.7 3.3 2 2 0 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.1 EIE83083.1 - 1.3e-05 25.2 2.0 0.18 11.7 0.0 3.5 4 0 0 4 4 4 2 AAA domain DUF258 PF03193.11 EIE83083.1 - 0.00014 21.0 0.1 0.0027 16.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 EIE83083.1 - 0.00016 21.1 0.0 0.011 15.1 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 EIE83083.1 - 0.00041 20.4 0.0 0.079 13.0 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EIE83083.1 - 0.00053 19.4 0.3 0.011 15.2 0.1 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_33 PF13671.1 EIE83083.1 - 0.00059 19.7 0.0 0.06 13.2 0.0 2.9 2 1 0 2 2 2 1 AAA domain cobW PF02492.14 EIE83083.1 - 0.0016 17.8 0.0 0.005 16.2 0.0 1.8 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.1 EIE83083.1 - 0.01 15.8 0.6 0.48 10.3 0.1 2.8 2 1 0 2 2 2 0 AAA ATPase domain AAA_17 PF13207.1 EIE83083.1 - 0.023 15.5 0.2 0.78 10.5 0.0 3.5 3 0 0 3 3 2 0 AAA domain SbcCD_C PF13558.1 EIE83083.1 - 0.046 13.6 0.0 0.28 11.1 0.0 2.3 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 EIE83083.1 - 0.052 13.8 0.8 0.24 11.7 0.0 2.6 3 0 0 3 3 1 0 AAA domain UPF0079 PF02367.12 EIE83083.1 - 0.068 12.7 0.6 1.3 8.6 0.2 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_19 PF13245.1 EIE83083.1 - 0.39 10.4 1.3 6.4 6.6 0.4 2.4 2 0 0 2 2 2 0 Part of AAA domain AAA_23 PF13476.1 EIE83083.1 - 0.8 9.9 5.7 0.72 10.1 0.1 3.1 3 0 0 3 3 3 0 AAA domain Cir_Bir_Yir PF06022.6 EIE83083.1 - 1.1 8.4 4.7 4 6.5 1.4 2.8 3 0 0 3 3 3 0 Plasmodium variant antigen protein Cir/Yir/Bir NUDIX_2 PF13869.1 EIE83084.1 - 1.2e-76 256.2 0.3 1.4e-76 256.0 0.2 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase Alpha-E PF04168.7 EIE83085.1 - 0.0075 15.6 0.1 0.01 15.2 0.1 1.2 1 0 0 1 1 1 1 A predicted alpha-helical domain with a conserved ER motif. Chloroplast_duf PF14476.1 EIE83085.1 - 0.042 12.6 2.6 0.058 12.1 1.8 1.3 1 0 0 1 1 1 0 Petal formation-expressed Herpes_UL92 PF03048.9 EIE83085.1 - 0.089 12.3 3.5 0.18 11.3 0.4 2.2 1 1 2 3 3 3 0 UL92 family ApoO PF09769.4 EIE83085.1 - 0.15 11.7 3.6 0.39 10.4 2.4 1.8 1 1 0 1 1 1 0 Apolipoprotein O Fucose_iso_N2 PF07882.7 EIE83085.1 - 0.3 10.7 3.4 0.38 10.3 0.8 1.9 1 1 1 2 2 2 0 L-fucose isomerase, second N-terminal domain Apolipoprotein PF01442.13 EIE83085.1 - 0.37 10.2 10.0 0.31 10.5 6.0 1.5 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain FUN14 PF04930.10 EIE83085.1 - 0.63 10.3 2.3 1.3 9.3 0.1 2.3 2 1 0 2 2 2 0 FUN14 family SlyX PF04102.7 EIE83085.1 - 1.5 9.2 5.5 0.39 11.1 0.3 2.7 3 1 0 3 3 3 0 SlyX DivIVA PF05103.8 EIE83085.1 - 2 8.4 15.5 0.23 11.5 2.9 2.3 1 1 1 2 2 2 0 DivIVA protein Baculo_p24 PF05073.7 EIE83085.1 - 2.6 7.5 5.8 1.2 8.6 1.3 2.0 1 1 1 2 2 2 0 Baculovirus P24 capsid protein COG2 PF06148.6 EIE83085.1 - 2.7 7.8 7.9 6.3 6.6 0.2 2.8 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Ribosomal_60s PF00428.14 EIE83085.1 - 4.1 7.8 11.3 3.5 8.0 5.7 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein FAD_binding_1 PF00667.15 EIE83086.1 - 5.8e-38 130.5 0.0 7.8e-38 130.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EIE83086.1 - 1.2e-17 64.2 0.0 8.7e-08 32.2 0.0 3.1 3 1 1 4 4 4 2 Flavodoxin NAD_binding_1 PF00175.16 EIE83086.1 - 1.2e-13 51.5 0.0 4.5e-13 49.7 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EIE83086.1 - 0.025 14.7 0.0 0.072 13.2 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain Rbsn PF11464.3 EIE83087.1 - 4.1e-09 35.8 0.1 8.8e-09 34.8 0.1 1.6 1 0 0 1 1 1 1 Rabenosyn Rab binding domain zf-C2H2_4 PF13894.1 EIE83087.1 - 0.00058 20.0 1.2 0.032 14.5 0.1 2.9 2 0 0 2 2 2 1 C2H2-type zinc finger zf-Di19 PF05605.7 EIE83087.1 - 0.0028 17.7 4.4 0.023 14.8 0.1 2.8 3 0 0 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding UPF0547 PF10571.4 EIE83087.1 - 0.0049 16.5 2.1 1.6 8.4 0.1 2.4 2 0 0 2 2 2 2 Uncharacterised protein family UPF0547 Seryl_tRNA_N PF02403.17 EIE83087.1 - 0.052 13.5 0.4 0.2 11.6 0.1 2.1 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain zf-met PF12874.2 EIE83087.1 - 0.066 13.4 0.1 0.19 11.9 0.1 1.8 1 0 0 1 1 1 0 Zinc-finger of C2H2 type Lectin_C PF00059.16 EIE83087.1 - 0.068 13.8 3.0 0.14 12.7 0.4 2.2 2 0 0 2 2 2 0 Lectin C-type domain zf-C2H2 PF00096.21 EIE83087.1 - 0.13 12.6 2.1 1.2 9.5 0.1 2.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-ribbon_3 PF13248.1 EIE83087.1 - 0.36 10.0 2.2 18 4.6 0.0 2.3 2 0 0 2 2 2 0 zinc-ribbon domain FYVE PF01363.16 EIE83087.1 - 0.81 9.6 4.8 5.1 7.0 0.2 2.9 3 0 0 3 3 3 0 FYVE zinc finger zf-RING_4 PF14570.1 EIE83088.1 - 0.31 10.6 3.5 2.9 7.5 0.3 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DUF3795 PF12675.2 EIE83088.1 - 0.47 10.6 4.6 0.91 9.7 3.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3795) Allantoicase PF03561.10 EIE83089.1 - 5e-86 285.7 0.0 2e-47 160.4 0.0 2.0 2 0 0 2 2 2 2 Allantoicase repeat CorA PF01544.13 EIE83090.1 - 9.4e-24 83.9 0.1 1.3e-23 83.5 0.1 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein MIS13 PF08202.6 EIE83090.1 - 0.095 11.7 0.0 0.62 9.0 0.0 2.0 2 0 0 2 2 2 0 Mis12-Mtw1 protein family FSH1 PF03959.8 EIE83092.1 - 1.8e-44 151.7 0.1 1.4e-33 116.1 0.0 2.0 1 1 1 2 2 2 2 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 EIE83092.1 - 0.0024 17.6 0.0 0.0037 17.0 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EIE83092.1 - 0.056 12.8 0.0 0.19 11.1 0.0 1.8 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DLH PF01738.13 EIE83092.1 - 0.14 11.3 0.0 0.2 10.9 0.0 1.3 1 1 0 1 1 1 0 Dienelactone hydrolase family Zn_clus PF00172.13 EIE83093.1 - 0.00016 21.5 15.0 0.00027 20.7 10.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_60s PF00428.14 EIE83093.1 - 0.048 14.0 1.2 0.048 14.0 0.8 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein BAF1_ABF1 PF04684.8 EIE83093.1 - 0.097 11.5 35.9 0.15 10.8 15.5 2.1 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Spore_coat_CotO PF14153.1 EIE83093.1 - 0.46 9.9 18.9 1.5 8.2 9.3 2.3 2 0 0 2 2 2 0 Spore coat protein CotO Ribosomal_L16 PF00252.13 EIE83094.1 - 7.7e-45 151.9 0.9 9.3e-45 151.6 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e HLH PF00010.21 EIE83096.1 - 1.5e-13 50.1 0.6 1.5e-13 50.1 0.4 1.7 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF484 PF04340.7 EIE83096.1 - 0.16 11.3 0.6 0.27 10.6 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function, DUF484 6PF2K PF01591.13 EIE83097.1 - 2.5e-65 219.6 0.1 3.2e-65 219.3 0.1 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EIE83097.1 - 6.7e-31 107.5 0.0 1.2e-30 106.6 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EIE83097.1 - 0.11 12.3 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Esterase_phd PF10503.4 EIE83098.1 - 0.078 12.2 3.7 0.099 11.8 2.6 1.0 1 0 0 1 1 1 0 Esterase PHB depolymerase Mucin PF01456.12 EIE83098.1 - 0.89 9.3 16.4 1.6 8.4 11.4 1.5 1 1 0 1 1 1 0 Mucin-like glycoprotein NDUF_B7 PF05676.8 EIE83099.1 - 2e-31 107.1 3.3 2.3e-31 106.9 2.3 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.5 EIE83099.1 - 0.0026 17.4 3.9 0.0034 17.1 2.6 1.3 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Endonuclease_5 PF04493.9 EIE83100.1 - 6.7e-46 156.2 0.0 7.8e-46 156.0 0.0 1.1 1 0 0 1 1 1 1 Endonuclease V DUF99 PF01949.11 EIE83100.1 - 0.005 15.9 0.0 0.0065 15.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF99 LIM_bind PF01803.11 EIE83101.1 - 1.8e-31 109.0 0.1 1.8e-31 109.0 0.1 5.7 3 2 1 4 4 4 1 LIM-domain binding protein PAT1 PF09770.4 EIE83101.1 - 3.3 5.8 119.3 0.77 7.9 16.4 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 RNase_PH PF01138.16 EIE83106.1 - 9.3e-36 123.0 0.1 1.5e-35 122.3 0.1 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EIE83106.1 - 0.0024 17.7 0.5 0.0043 16.9 0.3 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 His_Phos_1 PF00300.17 EIE83107.1 - 0.062 13.3 0.0 0.07 13.2 0.0 1.1 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) bZIP_2 PF07716.10 EIE83109.1 - 8.3e-13 47.9 16.7 8.3e-13 47.9 11.6 2.5 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 EIE83109.1 - 4e-11 42.7 14.7 4e-11 42.7 10.2 2.2 3 0 0 3 3 3 1 bZIP transcription factor bZIP_Maf PF03131.12 EIE83109.1 - 4.8e-05 23.5 12.6 4.8e-05 23.5 8.8 3.8 3 1 1 4 4 4 1 bZIP Maf transcription factor RRM_1 PF00076.17 EIE83110.1 - 2.4e-09 36.6 0.1 5.8e-09 35.4 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE83110.1 - 1.3e-08 34.6 0.1 2.6e-08 33.7 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE83110.1 - 5.1e-06 26.2 0.2 1.2e-05 25.0 0.2 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pilin_PilX PF11530.3 EIE83110.1 - 0.052 13.2 0.2 1.4 8.5 0.1 2.4 2 0 0 2 2 2 0 Minor type IV pilin, PilX Sod_Cu PF00080.15 EIE83111.1 - 1.7e-49 167.6 3.1 1.9e-49 167.4 2.1 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Mito_carr PF00153.22 EIE83112.1 - 2.1e-42 142.7 2.8 2.4e-23 81.6 0.1 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein DUF4508 PF14969.1 EIE83114.1 - 0.0063 16.4 0.2 0.016 15.2 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4508) adh_short PF00106.20 EIE83115.1 - 3.8e-25 88.7 0.3 4.8e-25 88.4 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIE83115.1 - 8.5e-24 84.6 0.0 1e-23 84.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIE83115.1 - 4.4e-09 36.2 0.1 6.3e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EIE83115.1 - 0.0024 16.8 0.2 0.0028 16.5 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 EIE83115.1 - 0.074 12.8 0.1 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EIE83115.1 - 0.099 12.0 0.3 0.13 11.7 0.2 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF2062 PF09835.4 EIE83116.1 - 4.8 6.7 5.8 1.9 8.1 0.6 2.2 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2062) Pkinase PF00069.20 EIE83117.1 - 2.9e-69 233.0 0.0 3.8e-69 232.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE83117.1 - 3.3e-27 95.1 0.0 1.3e-26 93.2 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE83117.1 - 1.1e-10 40.9 0.4 0.00098 18.1 0.0 3.1 2 1 0 3 3 3 3 Kinase-like YrbL-PhoP_reg PF10707.4 EIE83117.1 - 0.0071 15.7 0.1 0.53 9.5 0.0 2.2 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL APH PF01636.18 EIE83117.1 - 0.029 14.0 0.0 4.6 6.9 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 EIE83117.1 - 0.079 12.0 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Suc_Fer-like PF06999.7 EIE83118.1 - 3.2e-51 174.5 0.0 3.7e-51 174.3 0.0 1.0 1 0 0 1 1 1 1 Sucrase/ferredoxin-like NadA PF02445.11 EIE83118.1 - 0.038 12.8 0.0 0.065 12.0 0.0 1.3 1 0 0 1 1 1 0 Quinolinate synthetase A protein DUF460 PF04312.8 EIE83118.1 - 0.12 11.9 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF460) F-box-like PF12937.2 EIE83119.1 - 0.0011 18.6 0.8 0.0026 17.4 0.5 1.6 1 0 0 1 1 1 1 F-box-like HMD PF03201.11 EIE83122.1 - 0.032 14.1 0.0 0.056 13.3 0.0 1.4 1 0 0 1 1 1 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase Trigger_C PF05698.9 EIE83122.1 - 0.068 13.0 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Bacterial trigger factor protein (TF) C-terminus WD40 PF00400.27 EIE83123.1 - 8.6e-68 221.9 29.0 1.3e-11 43.9 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EIE83123.1 - 0.00039 19.8 0.0 1.4 8.4 0.0 4.3 5 0 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.6 EIE83123.1 - 0.0028 16.4 3.6 1.9 7.1 0.1 3.6 1 1 2 3 3 3 2 Nup133 N terminal like DUF4082 PF13313.1 EIE83123.1 - 0.038 13.4 2.1 9.7 5.6 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4082) Coatomer_WDAD PF04053.9 EIE83123.1 - 0.04 12.7 5.1 0.39 9.4 1.1 3.1 2 1 1 3 3 3 0 Coatomer WD associated region IKI3 PF04762.7 EIE83123.1 - 0.34 8.6 9.0 1.3 6.7 0.3 2.6 1 1 1 2 2 2 0 IKI3 family DUF2140 PF09911.4 EIE83124.1 - 0.1 11.7 0.2 0.14 11.3 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) DnaJ PF00226.26 EIE83126.1 - 7.5e-05 22.3 0.9 0.00087 18.9 0.0 2.8 2 0 0 2 2 2 1 DnaJ domain DUF3703 PF12487.3 EIE83126.1 - 0.062 12.9 0.0 0.17 11.5 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3703) CAF-1_p150 PF11600.3 EIE83126.1 - 3.9 6.7 36.0 0.5 9.7 15.0 2.3 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Adeno_E3_14_5 PF04834.7 EIE83127.1 - 5.3 7.5 9.0 5.8 7.4 0.3 2.9 2 1 1 3 3 3 0 Early E3 14.5 kDa protein IPK PF03770.11 EIE83128.1 - 0.16 11.5 0.8 0.65 9.5 0.0 1.9 2 0 0 2 2 2 0 Inositol polyphosphate kinase RVT_1 PF00078.22 EIE83129.1 - 1.3e-21 77.0 0.0 2.7e-21 75.9 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Mito_carr PF00153.22 EIE83130.1 - 4.7e-14 51.8 3.2 5.9e-10 38.7 0.5 2.9 2 1 0 2 2 2 2 Mitochondrial carrier protein NAD_binding_2 PF03446.10 EIE83131.1 - 9.7e-38 129.5 0.0 1.4e-37 129.0 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EIE83131.1 - 5.7e-33 113.5 0.0 9.3e-33 112.8 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase PDH PF02153.12 EIE83131.1 - 0.0071 15.2 0.0 0.009 14.9 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase UDPG_MGDP_dh_N PF03721.9 EIE83131.1 - 0.015 14.6 0.6 0.1 11.9 0.2 2.1 1 1 1 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Ribosomal_S7 PF00177.16 EIE83132.1 - 6.5e-36 123.1 3.4 8.1e-36 122.8 2.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e HGTP_anticodon2 PF12745.2 EIE83132.1 - 0.0026 16.9 0.5 0.0033 16.6 0.4 1.1 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs SPOC PF07744.8 EIE83133.1 - 5.2 7.5 9.9 47 4.5 2.4 3.8 2 1 1 3 3 3 0 SPOC domain HIT PF01230.18 EIE83134.1 - 3.8e-07 30.5 0.1 7.8e-07 29.5 0.0 1.5 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.3 EIE83134.1 - 0.043 14.0 0.0 0.069 13.3 0.0 1.4 1 0 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding Sugar_tr PF00083.19 EIE83135.1 - 4.9e-83 279.2 38.4 1.1e-79 268.1 26.6 2.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIE83135.1 - 1.6e-14 53.3 32.4 1e-09 37.6 3.0 3.4 2 1 1 3 3 3 3 Major Facilitator Superfamily Herpes_UL45 PF05473.7 EIE83135.1 - 0.016 14.6 0.1 0.039 13.3 0.1 1.7 1 0 0 1 1 1 0 UL45 protein NTP_transferase PF00483.18 EIE83136.1 - 1.9e-09 37.2 0.0 2.3e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase HTH_45 PF14947.1 EIE83137.1 - 0.015 15.0 0.0 0.038 13.8 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix HHH_8 PF14716.1 EIE83137.1 - 0.028 14.6 0.0 0.16 12.1 0.0 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix domain HTH_27 PF13463.1 EIE83137.1 - 0.14 12.5 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 Winged helix DNA-binding domain DUF1759 PF03564.10 EIE83138.1 - 7.3e-05 22.6 0.2 0.00011 21.9 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) Retrotrans_gag PF03732.12 EIE83138.1 - 0.0023 17.9 0.0 0.0047 16.9 0.0 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein TIP49 PF06068.8 EIE83140.1 - 6.8e-184 611.1 4.6 8e-184 610.9 3.2 1.0 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 EIE83140.1 - 1.2e-08 34.2 4.4 2.5e-05 23.4 0.0 3.2 2 1 1 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 EIE83140.1 - 1.7e-08 34.7 4.0 4.1e-05 23.8 0.0 3.6 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) DnaB_C PF03796.10 EIE83140.1 - 1.9e-06 26.9 0.2 3.4e-06 26.1 0.1 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_22 PF13401.1 EIE83140.1 - 4.3e-05 23.6 2.0 0.26 11.4 0.0 3.5 2 1 1 3 3 3 2 AAA domain AAA_5 PF07728.9 EIE83140.1 - 6.7e-05 22.6 0.4 0.12 12.0 0.0 3.2 2 2 1 3 3 3 2 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EIE83140.1 - 8.5e-05 21.8 1.9 0.0067 15.6 0.6 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 EIE83140.1 - 0.00026 20.8 0.3 1 9.2 0.0 3.3 3 1 0 3 3 3 2 AAA domain AAA_25 PF13481.1 EIE83140.1 - 0.00036 20.0 0.0 0.0018 17.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EIE83140.1 - 0.0011 19.0 0.0 0.0084 16.1 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain Sigma54_activat PF00158.21 EIE83140.1 - 0.0018 17.7 1.0 3.8 6.9 0.0 3.4 3 0 0 3 3 3 2 Sigma-54 interaction domain AAA_19 PF13245.1 EIE83140.1 - 0.0031 17.2 0.1 0.012 15.3 0.1 2.0 1 0 0 1 1 1 1 Part of AAA domain Parvo_NS1 PF01057.12 EIE83140.1 - 0.034 12.9 0.1 0.065 12.0 0.1 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_11 PF13086.1 EIE83140.1 - 0.055 13.0 1.0 0.069 12.7 0.1 1.6 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.1 EIE83140.1 - 0.088 12.7 0.0 0.088 12.7 0.0 2.0 2 0 0 2 2 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EIE83140.1 - 0.089 12.2 1.9 2.3 7.6 0.1 3.0 3 0 0 3 3 3 0 FtsK/SpoIIIE family PRK PF00485.13 EIE83141.1 - 1e-05 25.2 0.0 8.6e-05 22.1 0.0 2.1 1 1 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_23 PF13476.1 EIE83141.1 - 2e-05 24.9 0.4 4.9e-05 23.7 0.3 1.7 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EIE83141.1 - 4.3e-05 24.3 0.1 0.00021 22.0 0.1 2.3 1 1 0 1 1 1 1 AAA domain MobB PF03205.9 EIE83141.1 - 4.6e-05 23.1 0.0 0.0013 18.4 0.0 2.3 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 EIE83141.1 - 0.00018 21.8 0.2 0.002 18.4 0.0 2.5 3 0 0 3 3 3 1 AAA domain ATP_bind_1 PF03029.12 EIE83141.1 - 0.00071 19.1 0.1 0.0022 17.6 0.0 1.8 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein SRP54 PF00448.17 EIE83141.1 - 0.00083 18.8 0.0 0.0014 18.1 0.0 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_22 PF13401.1 EIE83141.1 - 0.0014 18.7 0.0 0.003 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EIE83141.1 - 0.0037 16.7 0.0 0.0089 15.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.14 EIE83141.1 - 0.0045 16.2 0.0 0.0097 15.1 0.0 1.5 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.7 EIE83141.1 - 0.0073 15.4 0.0 0.013 14.5 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin KAP_NTPase PF07693.9 EIE83141.1 - 0.0076 15.2 0.0 0.056 12.4 0.0 2.1 3 0 0 3 3 3 1 KAP family P-loop domain AstA PF04958.7 EIE83141.1 - 0.013 13.9 0.4 0.26 9.6 0.2 2.1 2 0 0 2 2 2 0 Arginine N-succinyltransferase beta subunit ArgK PF03308.11 EIE83141.1 - 0.016 14.0 0.0 0.025 13.3 0.0 1.2 1 0 0 1 1 1 0 ArgK protein AAA_14 PF13173.1 EIE83141.1 - 0.016 15.1 0.0 0.016 15.1 0.0 2.5 3 1 0 3 3 3 0 AAA domain AAA_16 PF13191.1 EIE83141.1 - 0.02 14.8 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.17 EIE83141.1 - 0.021 13.6 1.4 0.3 9.8 0.0 2.5 3 0 0 3 3 3 0 NB-ARC domain AAA_28 PF13521.1 EIE83141.1 - 0.03 14.2 0.0 0.067 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EIE83141.1 - 0.03 14.6 0.0 0.064 13.5 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.1 EIE83141.1 - 0.035 13.9 0.0 0.065 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EIE83141.1 - 0.045 13.5 0.0 0.086 12.6 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain cobW PF02492.14 EIE83141.1 - 0.062 12.7 0.0 0.097 12.1 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF2414 PF10309.4 EIE83141.1 - 0.098 12.3 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2414) NACHT PF05729.7 EIE83141.1 - 0.098 12.3 0.1 0.41 10.2 0.0 2.1 3 0 0 3 3 3 0 NACHT domain NTPase_1 PF03266.10 EIE83141.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 NTPase PQ-loop PF04193.9 EIE83142.1 - 2.9e-26 90.7 15.1 2.4e-13 49.3 0.1 3.5 3 1 1 4 4 4 2 PQ loop repeat MtN3_slv PF03083.11 EIE83142.1 - 0.24 11.2 8.1 1.6 8.6 0.4 2.7 2 1 0 2 2 2 0 Sugar efflux transporter for intercellular exchange Glyco_trans_2_3 PF13632.1 EIE83143.1 - 4.7e-17 62.3 0.8 7.8e-17 61.6 0.5 1.4 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 EIE83143.1 - 0.039 13.6 0.0 0.12 12.0 0.0 1.9 1 1 0 1 1 1 0 Glycosyl transferase family 2 EII-GUT PF03608.8 EIE83143.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 PTS system enzyme II sorbitol-specific factor Pkinase PF00069.20 EIE83144.1 - 1.2e-20 73.7 0.0 1.5e-20 73.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE83144.1 - 4.7e-08 32.4 0.0 5.3e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE83144.1 - 0.00044 19.2 0.0 0.00059 18.8 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EIE83144.1 - 0.017 14.8 0.1 0.033 13.8 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family GAS PF13851.1 EIE83145.1 - 0.027 13.6 26.2 0.13 11.4 12.2 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Phage_lysis PF03245.8 EIE83145.1 - 0.058 13.3 14.0 0.77 9.7 5.0 2.5 2 1 0 2 2 2 0 Bacteriophage Rz lysis protein Tht1 PF04163.7 EIE83145.1 - 0.068 11.5 8.9 0.074 11.4 6.2 1.1 1 0 0 1 1 1 0 Tht1-like nuclear fusion protein eIF3_N PF09440.5 EIE83145.1 - 0.1 12.7 11.4 0.095 12.8 6.4 2.1 1 1 0 2 2 2 0 eIF3 subunit 6 N terminal domain GTPase_Cys_C PF12631.2 EIE83145.1 - 0.24 11.8 3.5 0.27 11.6 0.4 2.5 2 2 0 2 2 2 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE Fzo_mitofusin PF04799.8 EIE83145.1 - 0.28 10.5 15.0 0.042 13.2 5.5 2.3 2 1 0 2 2 2 0 fzo-like conserved region TPR_MLP1_2 PF07926.7 EIE83145.1 - 0.45 10.2 23.7 6.9 6.4 13.3 2.7 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein PilJ PF13675.1 EIE83145.1 - 0.86 9.9 5.0 3.4 8.0 0.7 2.7 1 1 2 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term DivIC PF04977.10 EIE83145.1 - 0.94 9.0 19.1 5.1 6.6 0.1 3.5 2 1 1 3 3 3 0 Septum formation initiator ATG16 PF08614.6 EIE83145.1 - 0.96 9.2 24.8 3.9 7.2 6.9 2.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Spc7 PF08317.6 EIE83145.1 - 1.2 7.7 24.6 4.6 5.8 17.1 1.8 1 1 0 1 1 1 0 Spc7 kinetochore protein HisKA PF00512.20 EIE83145.1 - 1.9 8.5 4.9 3.4 7.7 0.1 3.0 3 1 0 3 3 3 0 His Kinase A (phospho-acceptor) domain CHD5 PF04420.9 EIE83145.1 - 2.2 7.9 12.8 0.65 9.6 5.6 2.1 1 1 1 2 2 2 0 CHD5-like protein SlyX PF04102.7 EIE83145.1 - 2.5 8.5 14.2 15 6.0 4.1 3.9 2 2 2 4 4 4 0 SlyX Glyco_hydro_63 PF03200.11 EIE83145.1 - 2.5 5.8 12.2 2.9 5.6 8.4 1.2 1 0 0 1 1 1 0 Mannosyl oligosaccharide glucosidase PEP-utilisers_N PF05524.8 EIE83145.1 - 3 7.6 11.0 0.91 9.3 2.2 2.9 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal DUF1843 PF08898.5 EIE83145.1 - 3.7 7.6 10.3 2.9 8.0 1.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF1843) DUF3450 PF11932.3 EIE83145.1 - 3.8 6.6 17.5 7.7 5.6 0.1 2.8 1 1 1 3 3 3 0 Protein of unknown function (DUF3450) CENP-F_leu_zip PF10473.4 EIE83145.1 - 9.3 6.1 27.2 3.4 7.5 15.6 2.0 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 EIE83145.1 - 9.4 5.7 22.2 2.8 7.4 12.0 2.0 1 1 1 2 2 2 0 IncA protein LCAT PF02450.10 EIE83146.1 - 1.1e-83 281.3 0.2 8.6e-83 278.4 0.1 2.0 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase Lipase_2 PF01674.13 EIE83146.1 - 0.007 15.6 0.1 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 2) Abhydrolase_5 PF12695.2 EIE83146.1 - 0.03 14.0 0.0 0.059 13.1 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family GAS2 PF02187.12 EIE83148.1 - 9e-05 22.1 0.0 0.00087 19.0 0.0 2.6 2 0 0 2 2 2 1 Growth-Arrest-Specific Protein 2 Domain Spectrin PF00435.16 EIE83148.1 - 0.00017 21.8 8.9 0.025 14.8 0.4 3.7 3 0 0 3 3 3 2 Spectrin repeat KAR9 PF08580.5 EIE83148.1 - 0.00054 18.3 50.7 0.01 14.1 24.5 3.2 2 1 0 2 2 2 2 Yeast cortical protein KAR9 DUF3658 PF12395.3 EIE83148.1 - 1.5 8.3 10.1 12 5.5 0.2 3.8 4 0 0 4 4 4 0 Protein of unknown function RVT_1 PF00078.22 EIE83149.1 - 5.9e-27 94.4 0.0 1.4e-26 93.2 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EIE83149.1 - 7.1e-18 64.3 2.2 2.7e-17 62.4 1.5 2.1 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EIE83149.1 - 1.2e-07 31.9 0.1 2.8e-07 30.7 0.1 1.7 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Lar_restr_allev PF14354.1 EIE83149.1 - 0.018 15.3 1.5 0.039 14.2 0.4 2.1 2 0 0 2 2 2 0 Restriction alleviation protein Lar Zn_Tnp_IS1595 PF12760.2 EIE83149.1 - 0.19 11.5 2.4 0.61 9.9 1.6 1.9 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.5 EIE83149.1 - 0.56 10.2 2.4 23 5.0 0.1 2.7 2 0 0 2 2 2 0 Zinc ribbon domain DDE_3 PF13358.1 EIE83151.1 - 1.3e-28 99.6 0.0 2.2e-28 98.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.14 EIE83151.1 - 0.00012 21.2 0.5 0.0011 18.2 0.4 2.1 1 1 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE83151.1 - 0.017 15.2 0.0 0.036 14.1 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain DUF2837 PF10997.3 EIE83152.1 - 0.2 10.7 3.8 0.25 10.4 2.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2837) HTH_Tnp_Tc3_2 PF01498.13 EIE83154.1 - 2.4e-08 33.8 0.3 2.4e-08 33.8 0.2 1.9 2 0 0 2 2 2 1 Transposase HTH_12 PF08461.5 EIE83154.1 - 0.053 13.2 0.1 0.14 11.8 0.1 1.7 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain HTH_21 PF13276.1 EIE83154.1 - 0.058 13.4 1.2 0.49 10.4 0.0 2.2 2 0 0 2 2 2 0 HTH-like domain HTH_Tnp_ISL3 PF13542.1 EIE83154.1 - 0.067 12.3 0.6 0.46 9.6 0.1 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_29 PF13551.1 EIE83154.1 - 0.15 12.1 2.1 4.4 7.4 0.1 2.3 1 1 1 2 2 2 0 Winged helix-turn helix DDE_3 PF13358.1 EIE83155.1 - 1.3e-19 70.4 0.0 2.3e-19 69.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE83155.1 - 4.1e-10 39.5 1.1 1.6e-09 37.6 0.7 2.1 1 0 0 1 1 1 1 Transposase HTH_Tnp_4 PF13613.1 EIE83155.1 - 0.00076 18.9 0.0 0.0014 18.0 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease HTH_23 PF13384.1 EIE83155.1 - 0.0051 16.4 0.0 0.013 15.1 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain FAM70 PF14967.1 EIE83155.1 - 0.04 13.1 0.0 0.06 12.5 0.0 1.2 1 0 0 1 1 1 0 FAM70 protein TPR_MLP1_2 PF07926.7 EIE83156.1 - 0.00012 21.8 0.3 0.00019 21.1 0.2 1.2 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein Phage_GP20 PF06810.6 EIE83156.1 - 0.0002 20.8 0.1 0.0003 20.2 0.1 1.2 1 0 0 1 1 1 1 Phage minor structural protein GP20 SlyX PF04102.7 EIE83156.1 - 0.0051 17.1 0.2 0.012 15.9 0.2 1.6 1 0 0 1 1 1 1 SlyX Med4 PF10018.4 EIE83156.1 - 0.013 14.9 0.1 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF972 PF06156.8 EIE83156.1 - 0.014 15.7 0.3 0.022 15.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Cluap1 PF10234.4 EIE83156.1 - 0.021 14.0 0.2 0.03 13.5 0.2 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 HALZ PF02183.13 EIE83156.1 - 0.028 14.1 1.1 0.071 12.8 0.8 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper Rogdi_lz PF10259.4 EIE83156.1 - 0.034 13.2 1.1 0.055 12.5 0.8 1.3 1 0 0 1 1 1 0 Rogdi leucine zipper containing protein MAD PF05557.8 EIE83156.1 - 0.044 11.8 0.9 0.062 11.3 0.6 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein DivIVA PF05103.8 EIE83156.1 - 0.052 13.6 0.1 0.087 12.8 0.1 1.3 1 0 0 1 1 1 0 DivIVA protein DivIC PF04977.10 EIE83156.1 - 0.059 12.8 0.1 0.11 11.9 0.1 1.5 1 0 0 1 1 1 0 Septum formation initiator Baculo_PEP_C PF04513.7 EIE83156.1 - 0.1 12.4 8.7 0.17 11.6 6.0 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 EIE83156.1 - 0.13 11.3 2.8 0.19 10.8 1.9 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Birna_RdRp PF04197.7 EIE83156.1 - 0.14 10.1 0.7 0.19 9.7 0.5 1.1 1 0 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) RVT_1 PF00078.22 EIE83157.1 - 5.6e-26 91.2 0.0 9.1e-26 90.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EIE83157.1 - 1.5e-12 47.1 0.0 4.5e-12 45.6 0.0 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase TPR_MLP1_2 PF07926.7 EIE83158.1 - 2.9e-06 27.0 1.6 4.7e-06 26.3 1.1 1.2 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein DivIVA PF05103.8 EIE83158.1 - 0.0023 17.9 0.1 0.0046 17.0 0.0 1.4 1 0 0 1 1 1 1 DivIVA protein Reo_sigmaC PF04582.7 EIE83158.1 - 0.0039 16.4 4.4 0.0056 15.9 3.1 1.2 1 0 0 1 1 1 1 Reovirus sigma C capsid protein DUF972 PF06156.8 EIE83158.1 - 0.0072 16.6 0.5 0.012 15.9 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF972) Phage_GP20 PF06810.6 EIE83158.1 - 0.0079 15.6 1.1 0.013 14.9 0.8 1.2 1 0 0 1 1 1 1 Phage minor structural protein GP20 Rogdi_lz PF10259.4 EIE83158.1 - 0.013 14.6 2.2 0.019 14.0 1.5 1.2 1 0 0 1 1 1 0 Rogdi leucine zipper containing protein DUF1875 PF08961.5 EIE83158.1 - 0.013 14.8 0.1 0.02 14.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1875) SlyX PF04102.7 EIE83158.1 - 0.015 15.6 0.7 0.05 13.9 0.5 1.9 1 1 0 1 1 1 0 SlyX HALZ PF02183.13 EIE83158.1 - 0.016 14.9 0.3 0.036 13.7 0.2 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper Med4 PF10018.4 EIE83158.1 - 0.018 14.4 0.3 0.026 13.9 0.2 1.2 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 CENP-F_leu_zip PF10473.4 EIE83158.1 - 0.019 14.8 0.1 0.034 13.9 0.1 1.5 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Mod_r PF07200.8 EIE83158.1 - 0.03 14.2 0.7 0.057 13.3 0.5 1.4 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Allexi_40kDa PF05549.6 EIE83158.1 - 0.04 13.2 2.4 0.054 12.7 1.7 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein RasGAP_C PF03836.10 EIE83158.1 - 0.04 13.5 0.2 0.06 13.0 0.2 1.2 1 0 0 1 1 1 0 RasGAP C-terminus MAD PF05557.8 EIE83158.1 - 0.069 11.2 0.9 0.093 10.8 0.6 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein Seryl_tRNA_N PF02403.17 EIE83158.1 - 0.097 12.6 0.6 0.18 11.7 0.4 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DivIC PF04977.10 EIE83158.1 - 0.12 11.8 2.0 0.22 11.0 0.9 1.8 1 1 0 1 1 1 0 Septum formation initiator Meiotic_rec114 PF03525.9 EIE83158.1 - 0.12 10.8 6.6 0.16 10.4 4.6 1.1 1 0 0 1 1 1 0 Meiotic recombination protein rec114 DUF2365 PF10157.4 EIE83158.1 - 0.18 11.6 1.5 0.53 10.1 0.6 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2365) TBPIP PF07106.8 EIE83158.1 - 0.21 11.0 1.3 0.33 10.4 0.9 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Retrotrans_gag PF03732.12 EIE83159.1 - 3.1e-08 33.5 2.6 6.2e-08 32.6 0.2 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein DDE_Tnp_IS1595 PF12762.2 EIE83161.1 - 3.1e-23 82.3 0.4 3.9e-23 81.9 0.3 1.1 1 0 0 1 1 1 1 ISXO2-like transposase domain DDE_Tnp_IS66 PF03050.9 EIE83161.1 - 0.029 13.5 0.1 0.039 13.1 0.1 1.1 1 0 0 1 1 1 0 Transposase IS66 family DDE_3 PF13358.1 EIE83162.1 - 1.2e-15 57.4 0.0 1.9e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE83162.1 - 3e-10 40.0 0.3 5.7e-10 39.1 0.2 1.5 1 0 0 1 1 1 1 Transposase SIS PF01380.17 EIE83163.1 - 0.071 12.7 0.1 0.1 12.1 0.1 1.2 1 0 0 1 1 1 0 SIS domain RVT_1 PF00078.22 EIE83164.1 - 1.3e-26 93.2 0.0 2.4e-26 92.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EIE83164.1 - 7.1e-15 54.6 0.0 1.8e-14 53.3 0.0 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EIE83164.1 - 4.6e-06 26.7 0.1 1.1e-05 25.5 0.1 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF972 PF06156.8 EIE83164.1 - 0.00017 21.8 1.5 0.00031 21.0 1.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF972) TSC22 PF01166.13 EIE83164.1 - 0.00031 20.6 0.9 0.00067 19.5 0.6 1.5 1 0 0 1 1 1 1 TSC-22/dip/bun family DUF904 PF06005.7 EIE83164.1 - 0.039 14.2 1.9 0.08 13.2 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DivIC PF04977.10 EIE83164.1 - 0.45 10.0 0.8 0.85 9.1 0.5 1.3 1 0 0 1 1 1 0 Septum formation initiator DUF4200 PF13863.1 EIE83164.1 - 2.3 8.1 4.5 3.6 7.5 3.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) RVT_1 PF00078.22 EIE83165.1 - 6.9e-30 104.0 0.2 1.5e-29 102.9 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease PF09668.5 EIE83165.1 - 5e-09 35.7 0.0 9.3e-09 34.9 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 EIE83165.1 - 3.1e-07 30.8 0.0 7.5e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 EIE83165.1 - 0.00039 20.2 2.1 0.00067 19.5 0.0 2.5 2 0 0 2 2 2 1 Retroviral aspartyl protease RVP_2 PF08284.6 EIE83165.1 - 0.00039 20.3 0.0 0.0009 19.1 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EIE83165.1 - 0.007 16.1 0.1 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1651 PF07864.6 EIE83166.1 - 0.62 10.2 3.5 0.9 9.6 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1651) OmpH PF03938.9 EIE83166.1 - 1.2 9.0 8.5 1.3 8.9 3.8 2.5 3 1 1 4 4 4 0 Outer membrane protein (OmpH-like) DDE_3 PF13358.1 EIE83168.1 - 4.9e-15 55.5 3.6 2.1e-11 43.7 2.2 2.4 1 1 1 2 2 2 2 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE83168.1 - 2e-06 27.7 1.7 8.8e-06 25.6 0.2 2.5 3 0 0 3 3 3 1 Transposase HTH_28 PF13518.1 EIE83168.1 - 0.0011 18.9 0.0 0.0034 17.3 0.0 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain rve PF00665.21 EIE83168.1 - 0.0055 16.8 0.6 0.017 15.1 0.1 2.1 2 1 1 3 3 3 1 Integrase core domain HTH_23 PF13384.1 EIE83168.1 - 0.031 13.9 0.7 0.13 11.9 0.0 2.4 3 0 0 3 3 3 0 Homeodomain-like domain HTH_32 PF13565.1 EIE83168.1 - 0.035 14.9 3.9 5.3 7.9 0.0 3.8 2 1 2 4 4 4 0 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.1 EIE83168.1 - 0.076 12.1 0.1 0.21 10.7 0.1 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 DUF1593 PF07632.6 EIE83169.1 - 0.13 11.5 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1593) DDE_3 PF13358.1 EIE83170.1 - 7.4e-21 74.4 0.0 1.5e-20 73.4 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE83170.1 - 2.7e-15 56.1 2.0 6.8e-15 54.8 0.3 2.3 3 0 0 3 3 2 1 Transposase HTH_29 PF13551.1 EIE83170.1 - 2.2e-06 27.7 0.2 7.1e-06 26.1 0.2 1.9 2 0 0 2 2 1 1 Winged helix-turn helix HTH_38 PF13936.1 EIE83170.1 - 1.2e-05 24.7 0.1 3.3e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_32 PF13565.1 EIE83170.1 - 5.5e-05 23.8 2.9 0.012 16.3 0.1 3.7 4 0 0 4 4 3 1 Homeodomain-like domain HTH_23 PF13384.1 EIE83170.1 - 7.5e-05 22.2 0.1 0.0028 17.2 0.0 2.7 2 0 0 2 2 2 1 Homeodomain-like domain Sigma70_r4_2 PF08281.7 EIE83170.1 - 0.00038 19.8 0.7 0.024 14.0 0.0 3.2 4 0 0 4 4 4 1 Sigma-70, region 4 HTH_28 PF13518.1 EIE83170.1 - 0.0013 18.7 0.0 0.0056 16.6 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_21 PF13276.1 EIE83170.1 - 0.0014 18.6 0.1 0.13 12.2 0.0 2.8 3 0 0 3 3 3 1 HTH-like domain HTH_7 PF02796.10 EIE83170.1 - 0.002 17.9 1.0 0.1 12.4 0.0 2.8 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase rve PF00665.21 EIE83170.1 - 0.0047 17.0 0.0 0.014 15.4 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain LacI PF00356.16 EIE83170.1 - 0.018 14.6 1.7 2.8 7.6 0.2 2.7 3 0 0 3 3 3 0 Bacterial regulatory proteins, lacI family HTH_Tnp_4 PF13613.1 EIE83170.1 - 0.022 14.2 0.1 0.057 12.9 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_36 PF13730.1 EIE83170.1 - 0.054 13.6 0.4 4.1 7.6 0.0 3.0 3 0 0 3 3 2 0 Helix-turn-helix domain CPSase_L_D3 PF02787.14 EIE83170.1 - 0.058 13.1 0.0 0.14 11.8 0.0 1.7 2 0 0 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain Sigma70_r4 PF04545.11 EIE83170.1 - 0.093 12.0 0.2 0.79 9.0 0.0 2.6 4 0 0 4 4 4 0 Sigma-70, region 4 DUF2642 PF10842.3 EIE83170.1 - 0.098 12.1 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2642) HTH_Tnp_ISL3 PF13542.1 EIE83170.1 - 0.17 11.0 2.8 8.4 5.6 0.0 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 HTH_17 PF12728.2 EIE83170.1 - 0.2 11.9 2.4 15 5.9 0.1 3.2 3 0 0 3 3 3 0 Helix-turn-helix domain DDE_3 PF13358.1 EIE83171.1 - 0.00061 19.5 0.0 0.002 17.8 0.0 1.8 2 1 0 2 2 2 1 DDE superfamily endonuclease HTH_30 PF13556.1 EIE83171.1 - 0.023 14.2 0.1 0.58 9.7 0.0 2.3 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain HTH_Tnp_4 PF13613.1 EIE83171.1 - 0.077 12.5 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE83172.1 - 9.3e-15 54.4 0.1 1.5e-14 53.7 0.1 1.4 1 0 0 1 1 1 1 Transposase FNIP_M PF14637.1 EIE83173.1 - 3.9e-57 193.5 5.9 3.9e-57 193.5 4.1 2.2 2 1 0 2 2 2 1 Folliculin-interacting protein middle domain FNIP_C PF14638.1 EIE83173.1 - 3.3e-10 39.6 0.1 6.8e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 Folliculin-interacting protein C-terminus FNIP_N PF14636.1 EIE83173.1 - 4.6e-09 36.8 0.2 4.6e-09 36.8 0.1 2.2 2 0 0 2 2 2 1 Folliculin-interacting protein N-terminus SlyX PF04102.7 EIE83174.1 - 0.00049 20.4 1.1 0.00058 20.1 0.7 1.0 1 0 0 1 1 1 1 SlyX DivIC PF04977.10 EIE83174.1 - 0.0014 18.0 2.2 0.0019 17.6 1.5 1.1 1 0 0 1 1 1 1 Septum formation initiator TMF_TATA_bd PF12325.3 EIE83174.1 - 0.0027 17.4 0.2 0.0027 17.4 0.1 1.1 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding Rab5-bind PF09311.6 EIE83174.1 - 0.0062 16.4 0.5 0.0062 16.4 0.3 1.1 1 0 0 1 1 1 1 Rabaptin-like protein FlgN PF05130.7 EIE83174.1 - 0.0081 16.4 1.9 0.009 16.2 1.3 1.0 1 0 0 1 1 1 1 FlgN protein PspA_IM30 PF04012.7 EIE83174.1 - 0.013 14.9 1.0 0.014 14.7 0.7 1.0 1 0 0 1 1 1 0 PspA/IM30 family FlxA PF14282.1 EIE83174.1 - 0.013 15.3 0.7 0.015 15.2 0.5 1.1 1 0 0 1 1 1 0 FlxA-like protein CASP_C PF08172.7 EIE83174.1 - 0.024 13.6 0.0 0.025 13.6 0.0 1.0 1 0 0 1 1 1 0 CASP C terminal Mod_r PF07200.8 EIE83174.1 - 0.03 14.2 0.4 0.03 14.2 0.3 1.0 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein DUF3422 PF11902.3 EIE83174.1 - 0.033 13.0 0.6 0.036 12.9 0.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3422) M_domain PF12938.2 EIE83174.1 - 0.034 13.9 0.3 0.034 13.9 0.2 1.0 1 0 0 1 1 1 0 M domain of GW182 CENP-H PF05837.7 EIE83174.1 - 0.043 14.0 0.4 0.049 13.8 0.3 1.0 1 0 0 1 1 1 0 Centromere protein H (CENP-H) TMF_DNA_bd PF12329.3 EIE83174.1 - 0.045 13.5 1.4 0.052 13.3 1.0 1.1 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding WEMBL PF05701.6 EIE83174.1 - 0.047 12.1 0.7 0.051 12.0 0.5 1.0 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Tektin PF03148.9 EIE83174.1 - 0.048 12.1 0.8 0.055 12.0 0.5 1.0 1 0 0 1 1 1 0 Tektin family Atg14 PF10186.4 EIE83174.1 - 0.051 12.5 0.3 0.052 12.4 0.2 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Phage_lysis PF03245.8 EIE83174.1 - 0.052 13.5 1.1 0.065 13.2 0.7 1.1 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein IncA PF04156.9 EIE83174.1 - 0.061 12.9 1.5 0.071 12.6 1.0 1.0 1 0 0 1 1 1 0 IncA protein DUF904 PF06005.7 EIE83174.1 - 0.064 13.5 0.8 0.069 13.4 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF904) Spc24 PF08286.6 EIE83174.1 - 0.064 12.9 0.4 0.07 12.8 0.3 1.0 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 TPR_MLP1_2 PF07926.7 EIE83174.1 - 0.065 12.9 2.3 0.081 12.6 1.6 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein bZIP_2 PF07716.10 EIE83174.1 - 0.079 12.7 3.2 0.1 12.4 2.2 1.2 1 0 0 1 1 1 0 Basic region leucine zipper DUF972 PF06156.8 EIE83174.1 - 0.083 13.2 0.2 0.084 13.2 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Nup54 PF13874.1 EIE83174.1 - 0.083 12.5 0.6 0.092 12.4 0.4 1.1 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 ADIP PF11559.3 EIE83174.1 - 0.088 12.7 1.6 0.089 12.6 1.1 1.0 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Filament PF00038.16 EIE83174.1 - 0.097 12.1 0.3 0.1 12.0 0.2 1.0 1 0 0 1 1 1 0 Intermediate filament protein Spc7 PF08317.6 EIE83174.1 - 0.1 11.2 0.3 0.11 11.0 0.2 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF948 PF06103.6 EIE83174.1 - 0.11 12.4 1.0 0.12 12.2 0.7 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) YlqD PF11068.3 EIE83174.1 - 0.11 12.5 0.6 0.12 12.4 0.4 1.0 1 0 0 1 1 1 0 YlqD protein SseC PF04888.7 EIE83174.1 - 0.21 10.8 1.4 0.23 10.7 1.0 1.0 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family NYD-SP28_assoc PF14775.1 EIE83174.1 - 0.25 11.0 3.0 0.32 10.7 2.1 1.2 1 0 0 1 1 1 0 Sperm tail C-terminal domain DASH_Hsk3 PF08227.6 EIE83174.1 - 3.8 7.7 9.5 2.4 8.4 3.5 2.0 1 1 1 2 2 2 0 DASH complex subunit Hsk3 like DUF1524 PF07510.6 EIE83176.1 - 0.1 12.4 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1524) NIF PF03031.13 EIE83177.1 - 6e-44 149.4 0.2 7.4e-44 149.2 0.2 1.0 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Ubiq_cyt_C_chap PF03981.7 EIE83178.1 - 3.2e-15 56.2 0.1 6.5e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone Ribosomal_L3 PF00297.17 EIE83179.1 - 4.5e-120 399.9 9.7 5.4e-120 399.6 6.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 FadA PF09403.5 EIE83179.1 - 2.1 8.3 6.4 1.4 8.9 2.2 2.1 1 1 1 2 2 2 0 Adhesion protein FadA Ribosomal_60s PF00428.14 EIE83181.1 - 5.4e-25 87.6 8.8 6.5e-25 87.3 6.1 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Ribosomal_S13 PF00416.17 EIE83182.1 - 3.8e-38 130.2 1.7 4.6e-38 129.9 1.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 EIE83182.1 - 0.0011 17.5 0.0 0.0013 17.4 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) DUF1822 PF08852.6 EIE83182.1 - 0.091 11.5 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1822) MutS_II PF05188.12 EIE83183.1 - 0.091 12.8 0.3 0.091 12.8 0.2 3.0 1 1 2 3 3 3 0 MutS domain II DEC-1_N PF04625.8 EIE83183.1 - 0.87 8.1 8.9 0.03 12.9 2.0 1.7 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region Reo_sigmaC PF04582.7 EIE83183.1 - 0.98 8.5 5.3 1.5 7.8 0.9 2.3 1 1 1 3 3 3 0 Reovirus sigma C capsid protein WD40 PF00400.27 EIE83184.1 - 1.2e-41 139.1 8.7 2.8e-09 36.5 0.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EIE83184.1 - 4.7e-26 90.4 0.2 1.1e-25 89.3 0.1 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Nucleoporin_N PF08801.6 EIE83184.1 - 0.047 12.4 0.1 0.095 11.4 0.1 1.6 1 1 0 1 1 1 0 Nup133 N terminal like Lectin_leg-like PF03388.8 EIE83185.1 - 8.3e-68 227.9 0.0 1.1e-67 227.5 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.14 EIE83185.1 - 0.00014 21.3 0.0 0.064 12.6 0.0 2.3 2 0 0 2 2 2 2 Legume lectin domain YhhN PF07947.9 EIE83185.1 - 0.07 12.4 0.3 0.12 11.6 0.2 1.4 1 0 0 1 1 1 0 YhhN-like protein BT1 PF03092.11 EIE83185.1 - 0.072 11.7 0.0 0.11 11.1 0.0 1.2 1 0 0 1 1 1 0 BT1 family Ribosomal_S21e PF01249.13 EIE83186.1 - 1.2e-39 134.0 0.0 1.3e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e SH3_1 PF00018.23 EIE83187.1 - 1.5e-05 24.2 0.1 2.5e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EIE83187.1 - 0.0015 18.0 0.1 0.0024 17.4 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Adeno_E3_14_5 PF04834.7 EIE83187.1 - 1.2 9.6 4.5 2.6 8.5 0.6 2.4 2 1 0 2 2 2 0 Early E3 14.5 kDa protein DUF1722 PF08349.6 EIE83188.1 - 0.081 12.7 0.1 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1722) Peroxin-3 PF04882.7 EIE83189.1 - 2.3e-100 336.3 7.8 2.7e-100 336.1 5.4 1.0 1 0 0 1 1 1 1 Peroxin-3 DUF3933 PF13069.1 EIE83189.1 - 0.28 10.8 1.9 17 5.1 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3933) AAA PF00004.24 EIE83190.1 - 1.1e-97 323.3 0.0 1e-47 161.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 EIE83190.1 - 7.4e-20 70.6 1.5 3.2e-19 68.6 0.7 2.3 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.7 EIE83190.1 - 1.8e-14 53.3 0.0 2.7e-05 23.3 0.0 3.5 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 EIE83190.1 - 3.2e-13 49.9 0.0 2.6e-07 30.7 0.0 3.1 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 EIE83190.1 - 9.2e-13 48.2 0.0 3.6e-06 26.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EIE83190.1 - 2.3e-12 46.8 0.3 8.8e-06 25.4 0.0 4.0 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EIE83190.1 - 2.5e-12 47.6 0.1 0.0001 23.1 0.0 3.3 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EIE83190.1 - 1.1e-11 45.0 0.1 0.0019 18.3 0.0 4.3 2 2 2 4 4 3 2 AAA domain AAA_16 PF13191.1 EIE83190.1 - 3.6e-10 40.1 0.0 0.0023 17.9 0.0 3.5 3 2 1 4 4 3 2 AAA ATPase domain CDC48_2 PF02933.12 EIE83190.1 - 1.3e-09 37.5 0.0 2.7e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 TIP49 PF06068.8 EIE83190.1 - 2e-09 36.6 0.7 0.00062 18.5 0.0 3.0 3 0 0 3 3 3 2 TIP49 C-terminus IstB_IS21 PF01695.12 EIE83190.1 - 2.4e-08 33.6 0.0 0.003 16.9 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein Zeta_toxin PF06414.7 EIE83190.1 - 5.3e-08 32.1 0.0 0.01 14.9 0.0 2.7 3 0 0 3 3 2 2 Zeta toxin AAA_19 PF13245.1 EIE83190.1 - 8e-08 31.9 0.8 0.0095 15.6 0.0 2.9 2 0 0 2 2 2 2 Part of AAA domain AAA_18 PF13238.1 EIE83190.1 - 2e-07 31.3 0.0 0.034 14.4 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EIE83190.1 - 2.2e-07 30.4 3.6 0.019 14.3 0.0 4.2 2 2 2 4 4 4 2 AAA domain Mg_chelatase PF01078.16 EIE83190.1 - 2.7e-07 29.9 0.2 0.022 13.8 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 EIE83190.1 - 3e-07 30.4 0.0 0.0084 16.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.22 EIE83190.1 - 1.8e-06 28.2 0.0 0.028 14.7 0.0 3.8 3 1 0 3 3 2 2 ABC transporter RNA_helicase PF00910.17 EIE83190.1 - 1.9e-06 27.9 0.0 0.016 15.3 0.0 2.9 2 0 0 2 2 2 2 RNA helicase AAA_28 PF13521.1 EIE83190.1 - 2.5e-06 27.5 0.0 0.11 12.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain ResIII PF04851.10 EIE83190.1 - 3.3e-06 27.0 0.0 0.0064 16.3 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Sigma54_activat PF00158.21 EIE83190.1 - 4.9e-06 26.1 0.0 0.17 11.3 0.0 3.3 2 1 0 2 2 2 2 Sigma-54 interaction domain Parvo_NS1 PF01057.12 EIE83190.1 - 5.3e-06 25.5 0.2 0.0094 14.8 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 DUF815 PF05673.8 EIE83190.1 - 1.8e-05 23.8 0.0 0.0049 15.8 0.0 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF815) KaiC PF06745.8 EIE83190.1 - 2.1e-05 23.7 1.0 0.93 8.5 0.0 3.4 2 1 1 3 3 3 2 KaiC Vps4_C PF09336.5 EIE83190.1 - 2.4e-05 24.1 0.0 0.00027 20.7 0.0 2.6 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain PhoH PF02562.11 EIE83190.1 - 3.1e-05 23.2 0.2 0.21 10.7 0.0 2.6 2 0 0 2 2 2 2 PhoH-like protein AAA_24 PF13479.1 EIE83190.1 - 5.5e-05 22.8 0.1 0.11 12.0 0.0 3.1 3 0 0 3 3 3 1 AAA domain Sigma54_activ_2 PF14532.1 EIE83190.1 - 6.4e-05 23.0 0.0 0.31 11.1 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain Arch_ATPase PF01637.13 EIE83190.1 - 7.2e-05 22.5 0.0 2.2 7.9 0.1 3.4 2 1 1 3 3 3 2 Archaeal ATPase Bac_DnaA PF00308.13 EIE83190.1 - 0.00011 21.9 0.0 0.61 9.6 0.0 2.6 2 0 0 2 2 2 2 Bacterial dnaA protein AAA_11 PF13086.1 EIE83190.1 - 0.00016 21.3 0.0 0.29 10.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.4 EIE83190.1 - 0.00022 20.3 0.0 0.37 9.7 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_3 PF07726.6 EIE83190.1 - 0.00023 20.7 0.0 0.6 9.7 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EIE83190.1 - 0.00034 20.2 0.1 0.51 9.9 0.0 3.5 3 0 0 3 3 3 1 NACHT domain NB-ARC PF00931.17 EIE83190.1 - 0.0014 17.5 0.0 0.27 10.0 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain NTPase_1 PF03266.10 EIE83190.1 - 0.0032 17.1 0.9 1.2 8.8 0.0 3.8 4 0 0 4 4 3 1 NTPase AAA_30 PF13604.1 EIE83190.1 - 0.0038 16.8 0.0 1.4 8.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 EIE83190.1 - 0.0054 16.2 0.0 0.23 10.9 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase T2SE PF00437.15 EIE83190.1 - 0.0097 14.8 0.0 0.62 8.9 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein SKI PF01202.17 EIE83190.1 - 0.02 14.7 0.0 7.7 6.3 0.0 2.7 2 0 0 2 2 2 0 Shikimate kinase ATP-synt_ab PF00006.20 EIE83190.1 - 0.029 13.8 0.0 7.4 6.0 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Cytidylate_kin2 PF13189.1 EIE83190.1 - 0.03 14.2 0.0 0.71 9.7 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase-like family AAA_10 PF12846.2 EIE83190.1 - 0.03 13.7 1.4 5.2 6.4 0.0 3.8 3 1 1 4 4 4 0 AAA-like domain UPF0079 PF02367.12 EIE83190.1 - 0.067 12.8 0.1 3.8 7.1 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 KTI12 PF08433.5 EIE83190.1 - 0.069 12.3 0.0 7.6 5.6 0.0 2.5 2 0 0 2 2 2 0 Chromatin associated protein KTI12 IPT PF01745.11 EIE83190.1 - 0.095 11.8 0.1 4.8 6.2 0.0 2.2 2 0 0 2 2 2 0 Isopentenyl transferase Zot PF05707.7 EIE83190.1 - 0.1 12.0 0.1 16 4.9 0.0 3.2 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) MobB PF03205.9 EIE83190.1 - 0.26 10.9 2.2 9.4 5.9 0.0 3.8 4 0 0 4 4 4 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 EIE83190.1 - 0.42 10.9 2.6 4 7.7 0.0 2.9 3 1 0 3 3 2 0 AAA domain Peptidase_C48 PF02902.14 EIE83191.1 - 5.7e-08 32.6 0.1 1.1e-07 31.7 0.1 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Ribosomal_L50 PF10501.4 EIE83192.1 - 5.2e-15 55.3 5.4 7.1e-15 54.9 3.8 1.3 1 0 0 1 1 1 1 Ribosomal subunit 39S NdhM PF10664.4 EIE83192.1 - 0.0068 16.2 0.6 0.01 15.7 0.4 1.4 1 0 0 1 1 1 1 Cyanobacterial and plastid NDH-1 subunit M Apc13p PF05839.6 EIE83192.1 - 0.056 13.4 0.9 0.11 12.4 0.7 1.6 1 1 0 1 1 1 0 Apc13p protein DUF4466 PF14725.1 EIE83192.1 - 0.091 12.0 0.4 0.11 11.8 0.2 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4466) K-box PF01486.12 EIE83192.1 - 0.25 11.1 2.5 0.42 10.4 1.7 1.4 1 0 0 1 1 1 0 K-box region Ribosomal_S13_N PF08069.7 EIE83193.1 - 2.3e-31 107.4 0.2 5.1e-31 106.2 0.1 1.6 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 EIE83193.1 - 4.2e-25 87.3 0.3 8e-25 86.4 0.1 1.5 2 0 0 2 2 2 1 Ribosomal protein S15 Arm PF00514.18 EIE83194.1 - 1.9e-46 154.3 23.0 2.7e-09 36.4 0.2 9.4 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EIE83194.1 - 7.1e-18 64.6 9.4 0.00023 21.3 0.4 6.6 1 1 6 7 7 7 7 HEAT repeats HEAT PF02985.17 EIE83194.1 - 8.3e-12 44.1 9.8 0.33 11.1 0.0 7.7 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.1 EIE83194.1 - 5.2e-11 42.6 11.0 0.02 15.4 0.0 6.3 4 1 2 6 6 6 4 HEAT-like repeat Adaptin_N PF01602.15 EIE83194.1 - 2.8e-09 35.8 8.0 1.3e-08 33.6 5.6 2.0 1 1 0 1 1 1 1 Adaptin N terminal region Arm_2 PF04826.8 EIE83194.1 - 8.2e-06 25.1 5.4 0.0012 18.0 0.4 2.8 1 1 2 3 3 3 3 Armadillo-like V-ATPase_H_C PF11698.3 EIE83194.1 - 0.0099 15.7 5.8 7.5 6.4 0.1 4.4 4 1 1 5 5 5 2 V-ATPase subunit H CTNNBL PF08216.6 EIE83194.1 - 0.014 14.9 2.9 1.8 8.1 0.2 3.8 3 0 0 3 3 3 0 Catenin-beta-like, Arm-motif containing nuclear Vac14_Fab1_bd PF12755.2 EIE83194.1 - 0.31 11.4 3.0 32 4.9 0.0 3.7 4 1 1 5 5 5 0 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 EIE83194.1 - 4.1 7.2 8.8 22 4.8 0.1 4.3 4 2 1 5 5 5 0 non-SMC mitotic condensation complex subunit 1 Ytp1 PF10355.4 EIE83195.1 - 2.8e-53 180.8 14.1 5.9e-53 179.8 9.8 1.4 1 1 0 1 1 1 1 Protein of unknown function (Ytp1) DUF1201 PF06716.6 EIE83195.1 - 0.00064 19.4 2.2 0.00075 19.2 0.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1201) Cytochrom_B561 PF03188.11 EIE83195.1 - 0.016 15.0 0.5 0.016 15.0 0.3 3.5 3 1 0 3 3 3 0 Eukaryotic cytochrome b561 PIRT PF15099.1 EIE83195.1 - 0.31 10.2 5.9 0.22 10.7 0.3 2.6 2 1 1 3 3 3 0 Phosphoinositide-interacting protein family ATP_synt_H PF05493.8 EIE83195.1 - 0.91 9.6 4.3 0.26 11.3 0.2 2.2 2 0 0 2 2 2 0 ATP synthase subunit H DivIC PF04977.10 EIE83199.1 - 0.0022 17.4 0.1 0.004 16.6 0.1 1.4 1 0 0 1 1 1 1 Septum formation initiator SlyX PF04102.7 EIE83199.1 - 0.017 15.4 0.3 0.055 13.8 0.2 1.9 1 0 0 1 1 1 0 SlyX Rab5-bind PF09311.6 EIE83199.1 - 0.045 13.6 0.4 0.081 12.8 0.3 1.4 1 0 0 1 1 1 0 Rabaptin-like protein DUF4140 PF13600.1 EIE83199.1 - 0.051 14.0 0.3 0.13 12.7 0.2 1.6 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) TMF_DNA_bd PF12329.3 EIE83199.1 - 0.062 13.1 0.5 0.11 12.2 0.3 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding TMF_TATA_bd PF12325.3 EIE83199.1 - 0.083 12.6 0.1 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF4164 PF13747.1 EIE83199.1 - 0.11 12.6 1.5 2.9 8.0 0.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) MCPVI PF02993.9 EIE83199.1 - 5.6 7.0 7.8 7.5 6.6 5.4 1.1 1 0 0 1 1 1 0 Minor capsid protein VI DMRL_synthase PF00885.14 EIE83201.1 - 2.1e-44 150.6 0.3 3e-29 101.5 0.1 2.0 2 0 0 2 2 2 2 6,7-dimethyl-8-ribityllumazine synthase Spo0A_C PF08769.6 EIE83201.1 - 0.09 12.6 0.1 7.2 6.5 0.0 2.3 2 0 0 2 2 2 0 Sporulation initiation factor Spo0A C terminal RNA_pol_N PF01194.12 EIE83204.1 - 8.1e-31 105.8 0.3 9.4e-31 105.6 0.2 1.0 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit KOW PF00467.24 EIE83205.1 - 7e-11 41.3 2.4 7e-11 41.3 1.7 1.7 2 1 0 2 2 2 1 KOW motif DUF1442 PF07279.6 EIE83205.1 - 0.013 14.6 1.1 0.016 14.2 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1442) 6PF2K PF01591.13 EIE83207.1 - 8.6e-76 253.8 0.1 1.1e-75 253.5 0.1 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EIE83207.1 - 6.6e-19 68.5 0.1 3.1e-17 63.1 0.0 2.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EIE83207.1 - 2.8e-05 24.0 0.0 5.4e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EIE83207.1 - 0.0052 17.5 0.2 0.025 15.3 0.1 2.3 2 1 0 2 2 2 1 AAA domain FAR1 PF03101.10 EIE83208.1 - 3e-06 27.6 0.4 3e-06 27.6 0.3 2.1 2 0 0 2 2 2 1 FAR1 DNA-binding domain DBD_Tnp_Mut PF03108.10 EIE83208.1 - 7.3e-06 25.4 1.7 0.012 15.1 0.0 2.4 2 0 0 2 2 2 2 MuDR family transposase AFT PF08731.6 EIE83208.1 - 8 6.6 11.5 0.27 11.4 1.3 2.4 2 1 0 2 2 2 0 Transcription factor AFT HLH PF00010.21 EIE83209.1 - 8.3e-10 38.2 0.8 2.6e-09 36.6 0.5 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Ribosomal_L16 PF00252.13 EIE83210.1 - 6.9e-45 152.0 0.9 8.3e-45 151.8 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Zn_clus PF00172.13 EIE83211.1 - 0.00014 21.6 15.0 0.00024 20.9 10.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain YjgP_YjgQ PF03739.9 EIE83211.1 - 2.8 6.6 7.4 4.8 5.8 5.2 1.3 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family Pox_Ag35 PF03286.9 EIE83211.1 - 3.3 7.2 14.0 0.086 12.3 4.8 2.0 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Na_trans_assoc PF06512.8 EIE83211.1 - 5.9 6.7 15.2 3.7 7.4 8.5 2.0 2 0 0 2 2 2 0 Sodium ion transport-associated FSH1 PF03959.8 EIE83213.1 - 7.3e-34 117.0 0.0 8e-34 116.9 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 EIE83213.1 - 0.00025 20.8 0.0 0.00029 20.5 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EIE83213.1 - 0.0095 15.3 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase BAAT_C PF08840.6 EIE83213.1 - 0.13 12.0 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal GCR1_C PF12550.3 EIE83214.1 - 5.1e-26 90.3 0.7 5.1e-25 87.1 0.2 2.6 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes DUF3357 PF11837.3 EIE83215.1 - 0.14 12.0 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) PDEase_I PF00233.14 EIE83217.1 - 1.1e-51 175.9 0.4 3.1e-46 158.0 0.0 2.2 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase Mss4 PF04421.8 EIE83218.1 - 3e-17 62.2 0.1 3e-17 62.2 0.1 2.3 2 1 1 3 3 3 1 Mss4 protein SMN PF06003.7 EIE83218.1 - 0.0089 15.1 1.6 0.0089 15.1 1.1 2.5 1 1 2 3 3 3 1 Survival motor neuron protein (SMN) Pex14_N PF04695.8 EIE83218.1 - 0.1 12.6 3.4 0.25 11.3 2.3 1.7 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Apolipoprotein PF01442.13 EIE83219.1 - 0.0003 20.3 51.2 0.0032 16.9 12.1 4.1 1 1 2 3 3 3 2 Apolipoprotein A1/A4/E domain LEA_4 PF02987.11 EIE83219.1 - 0.0011 18.7 6.6 0.0011 18.7 4.6 6.1 4 1 0 5 5 5 2 Late embryogenesis abundant protein DUF883 PF05957.8 EIE83219.1 - 0.015 15.6 11.2 0.015 15.6 7.8 6.4 3 2 3 6 6 6 0 Bacterial protein of unknown function (DUF883) Baculo_PEP_C PF04513.7 EIE83219.1 - 0.6 9.9 19.8 0.82 9.4 0.4 4.0 3 2 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus zf-RVT PF13966.1 EIE83220.1 - 0.0096 16.2 0.1 0.013 15.7 0.1 1.3 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase PMSI1 PF15322.1 EIE83222.1 - 2.4 7.1 5.2 2.8 6.9 3.6 1.1 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative NUDIX_2 PF13869.1 EIE83223.1 - 1.2e-61 207.3 0.2 1.3e-61 207.2 0.2 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase NDUF_B7 PF05676.8 EIE83225.1 - 5.8e-31 105.7 3.2 6.6e-31 105.5 2.2 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.5 EIE83225.1 - 0.0019 17.9 3.4 0.0024 17.5 2.3 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like DUF3684 PF12449.3 EIE83226.1 - 2.5e-269 896.2 14.8 2.5e-267 889.6 2.6 3.0 3 1 0 3 3 3 2 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.1 EIE83226.1 - 0.00055 19.6 0.0 0.0015 18.1 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CUE PF02845.11 EIE83226.1 - 0.032 13.7 0.1 0.069 12.6 0.0 1.5 1 0 0 1 1 1 0 CUE domain Glyco_tranf_2_3 PF13641.1 EIE83227.1 - 2.3e-19 70.0 0.2 3e-13 50.1 0.4 2.1 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Chitin_synth_2 PF03142.10 EIE83227.1 - 3.6e-12 45.4 7.1 5.4e-08 31.6 4.9 3.5 2 1 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 EIE83227.1 - 1.1e-09 38.3 10.0 4.5e-09 36.2 7.0 2.2 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 EIE83227.1 - 4.3e-08 33.0 0.0 0.012 15.3 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EIE83227.1 - 4.9e-06 25.9 0.1 8.6e-06 25.1 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 LIM_bind PF01803.11 EIE83228.1 - 1.7e-24 86.2 0.0 1.7e-24 86.2 0.0 5.5 3 2 1 4 4 4 1 LIM-domain binding protein Mem_trans PF03547.13 EIE83228.1 - 0.023 13.0 3.6 0.023 13.0 2.5 1.4 1 0 0 1 1 1 0 Membrane transport protein SGT1 PF07093.6 EIE83228.1 - 0.16 10.3 28.0 0.31 9.3 19.4 1.4 1 0 0 1 1 1 0 SGT1 protein GAGA_bind PF06217.7 EIE83228.1 - 2.7 7.8 38.0 0.63 9.9 21.7 2.1 2 0 0 2 2 2 0 GAGA binding protein-like family DUF572 PF04502.8 EIE83228.1 - 2.8 7.0 35.2 0.35 10.0 20.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF572) FAM176 PF14851.1 EIE83228.1 - 5.9 6.5 10.7 18 4.9 7.4 2.0 1 0 0 1 1 1 0 FAM176 family NMDAR2_C PF10565.4 EIE83229.1 - 0.011 14.4 0.3 0.015 14.0 0.2 1.1 1 0 0 1 1 1 0 N-methyl D-aspartate receptor 2B3 C-terminus Syntaxin_2 PF14523.1 EIE83229.1 - 0.015 15.2 9.0 0.015 15.2 6.3 2.0 2 0 0 2 2 2 0 Syntaxin-like protein HAP1_N PF04849.8 EIE83229.1 - 0.32 9.8 19.9 2 7.2 14.0 1.8 1 1 0 1 1 1 0 HAP1 N-terminal conserved region DUF948 PF06103.6 EIE83229.1 - 1.3 8.9 5.7 2.4 8.1 2.2 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) FAM72 PF14976.1 EIE83230.1 - 2.3e-21 76.1 2.6 2.3e-21 76.1 1.8 1.6 2 0 0 2 2 2 1 FAM72 protein zf-DHHC PF01529.15 EIE83230.1 - 0.0077 15.6 0.2 0.0077 15.6 0.2 2.5 3 0 0 3 3 3 2 DHHC palmitoyltransferase Ndr PF03096.9 EIE83231.1 - 0.11 10.9 0.9 0.11 10.9 0.6 1.0 1 0 0 1 1 1 0 Ndr family COG5 PF10392.4 EIE83233.1 - 2.8e-16 59.6 10.6 3.2e-16 59.4 0.2 3.5 4 0 0 4 4 4 2 Golgi transport complex subunit 5 Taeniidae_ag PF05596.6 EIE83233.1 - 0.26 11.1 1.8 3.2 7.6 0.0 3.4 3 0 0 3 3 3 0 Taeniidae antigen RRM_1 PF00076.17 EIE83234.1 - 6.9e-10 38.4 0.3 1.7e-09 37.1 0.2 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE83234.1 - 4.3e-09 36.2 0.1 1e-08 35.0 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE83234.1 - 1.5e-05 24.7 0.5 3.4e-05 23.6 0.3 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Shikimate_DH PF01488.15 EIE83234.1 - 0.037 14.1 0.0 0.09 12.8 0.0 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase PAT1 PF09770.4 EIE83234.1 - 8.2 4.5 47.7 0.81 7.8 23.3 2.4 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Kunitz_BPTI PF00014.18 EIE83235.1 - 0.012 15.7 0.3 0.014 15.5 0.2 1.2 1 0 0 1 1 1 0 Kunitz/Bovine pancreatic trypsin inhibitor domain Sod_Cu PF00080.15 EIE83236.1 - 4.7e-50 169.4 3.2 5.5e-50 169.2 2.2 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) CHRD PF07452.7 EIE83236.1 - 0.17 12.5 0.7 3.4 8.2 0.1 2.1 1 1 1 2 2 2 0 CHRD domain DUF4508 PF14969.1 EIE83238.1 - 0.0047 16.9 0.3 0.0098 15.8 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4508) Bap31 PF05529.7 EIE83238.1 - 0.36 10.2 6.9 3.6 7.0 0.5 2.3 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like adh_short PF00106.20 EIE83239.1 - 1.1e-24 87.2 0.2 1.4e-24 86.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIE83239.1 - 4.4e-24 85.5 0.0 5.3e-24 85.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIE83239.1 - 3.4e-09 36.6 0.0 4.9e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EIE83239.1 - 0.004 16.1 0.1 0.0047 15.8 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 EIE83239.1 - 0.1 12.3 0.1 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase PH PF00169.24 EIE83240.1 - 2.5e-05 24.4 0.0 6.9e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 PH domain CDP-OH_P_transf PF01066.16 EIE83241.1 - 3e-13 49.9 4.1 3.9e-13 49.5 2.8 1.2 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Pkinase PF00069.20 EIE83242.1 - 2.4e-06 26.9 0.0 3.3e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.20 EIE83243.1 - 3.6e-36 124.6 0.0 5.1e-36 124.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE83243.1 - 3.1e-14 52.6 0.0 3.9e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.1 EIE83243.1 - 0.012 15.2 0.1 0.028 14.0 0.1 1.5 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF4604 PF15377.1 EIE83244.1 - 6.5e-18 65.4 25.9 7.6e-18 65.2 18.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) DUF740 PF05340.7 EIE83244.1 - 3.1 6.0 15.4 3.6 5.8 10.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF740) GAGA_bind PF06217.7 EIE83244.1 - 4.9 7.0 9.3 5.4 6.8 6.4 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family DUF4288 PF14119.1 EIE83245.1 - 0.081 13.0 0.0 0.083 13.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4288) DUF4238 PF14022.1 EIE83245.1 - 0.12 11.5 0.2 0.14 11.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4238) PPR_2 PF13041.1 EIE83246.1 - 3.8e-58 193.2 32.8 1.4e-11 44.1 0.0 10.5 3 2 8 11 11 11 10 PPR repeat family PPR PF01535.15 EIE83246.1 - 9.8e-39 128.6 22.4 8.6e-05 22.2 0.0 12.1 12 0 0 12 12 12 8 PPR repeat PPR_1 PF12854.2 EIE83246.1 - 3.8e-37 125.4 11.6 1.5e-06 27.5 0.1 10.2 10 0 0 10 10 10 9 PPR repeat PPR_3 PF13812.1 EIE83246.1 - 2.7e-29 98.9 0.9 0.028 14.7 0.0 11.1 11 0 0 11 11 11 6 Pentatricopeptide repeat domain Glyco_transf_22 PF03901.12 EIE83248.1 - 4.9e-29 101.5 10.5 6.5e-29 101.1 7.2 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family VOMI PF03762.12 EIE83251.1 - 0.05 13.5 0.1 2.1 8.2 0.1 2.1 1 1 0 1 1 1 0 Vitelline membrane outer layer protein I (VOMI) LRR_6 PF13516.1 EIE83252.1 - 1.5e-05 24.6 7.5 1.3 9.2 0.0 6.4 8 0 0 8 8 8 3 Leucine Rich repeat LRR_8 PF13855.1 EIE83252.1 - 0.00021 21.0 6.8 0.19 11.4 0.4 3.7 2 1 1 3 3 3 3 Leucine rich repeat LRR_7 PF13504.1 EIE83252.1 - 0.0062 16.5 1.7 1.1e+02 3.7 0.0 5.4 5 0 0 5 5 5 0 Leucine rich repeat RAI16-like PF10257.4 EIE83253.1 - 2.7e-50 171.2 0.1 4.6e-50 170.5 0.1 1.4 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein PRiA4_ORF3 PF07929.6 EIE83253.1 - 0.083 12.2 0.3 0.18 11.2 0.2 1.5 1 0 0 1 1 1 0 Plasmid pRiA4b ORF-3-like protein SpoU_methylase PF00588.14 EIE83254.1 - 2.7e-33 114.8 0.1 8.5e-33 113.2 0.0 1.8 2 0 0 2 2 2 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.7 EIE83254.1 - 1.8e-13 50.4 0.1 4.3e-13 49.2 0.0 1.7 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding AAA_14 PF13173.1 EIE83254.1 - 0.042 13.7 0.0 0.3 10.9 0.0 2.0 1 1 1 2 2 2 0 AAA domain Septin PF00735.13 EIE83255.1 - 4e-114 380.3 1.0 5.8e-114 379.8 0.7 1.2 1 0 0 1 1 1 1 Septin GTP_EFTU PF00009.22 EIE83255.1 - 7.7e-08 31.9 0.1 9.3e-07 28.4 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EIE83255.1 - 3.7e-07 30.0 0.1 9.2e-07 28.8 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EIE83255.1 - 7.1e-07 28.5 0.0 1.9e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Ras PF00071.17 EIE83255.1 - 0.00025 20.4 1.6 0.00067 19.0 0.5 2.1 2 1 0 2 2 2 1 Ras family Gtr1_RagA PF04670.7 EIE83255.1 - 0.00035 19.7 0.0 0.00087 18.4 0.0 1.7 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EIE83255.1 - 0.00067 20.1 0.0 0.0019 18.7 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein Pox_A32 PF04665.7 EIE83255.1 - 0.0013 18.0 1.1 0.006 15.8 0.1 2.1 2 0 0 2 2 2 1 Poxvirus A32 protein AAA_22 PF13401.1 EIE83255.1 - 0.0018 18.4 0.8 0.0046 17.0 0.0 2.1 2 1 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 EIE83255.1 - 0.0038 16.7 0.1 0.0095 15.4 0.1 1.6 1 0 0 1 1 1 1 FtsK/SpoIIIE family IIGP PF05049.8 EIE83255.1 - 0.0046 15.8 0.0 0.0081 15.0 0.0 1.3 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) T2SE PF00437.15 EIE83255.1 - 0.01 14.7 0.2 0.018 13.9 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AIG1 PF04548.11 EIE83255.1 - 0.014 14.5 0.1 0.014 14.5 0.1 1.8 2 0 0 2 2 2 0 AIG1 family RNA_helicase PF00910.17 EIE83255.1 - 0.014 15.5 0.2 0.058 13.5 0.1 2.1 1 1 1 2 2 2 0 RNA helicase Sigma54_activat PF00158.21 EIE83255.1 - 0.021 14.2 0.1 0.038 13.4 0.1 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_33 PF13671.1 EIE83255.1 - 0.027 14.3 0.3 0.16 11.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EIE83255.1 - 0.028 14.7 1.1 0.22 11.8 0.0 2.4 2 0 0 2 2 2 0 ABC transporter AAA_10 PF12846.2 EIE83255.1 - 0.036 13.4 0.0 0.067 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain AAA_24 PF13479.1 EIE83255.1 - 0.044 13.3 0.4 0.077 12.5 0.3 1.7 1 1 0 1 1 1 0 AAA domain MobB PF03205.9 EIE83255.1 - 0.075 12.7 0.1 0.15 11.7 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Fzo_mitofusin PF04799.8 EIE83255.1 - 0.085 12.2 1.1 0.21 10.9 0.8 1.6 1 0 0 1 1 1 0 fzo-like conserved region AAA_29 PF13555.1 EIE83255.1 - 0.088 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain IstB_IS21 PF01695.12 EIE83255.1 - 0.095 12.1 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein ATP_bind_1 PF03029.12 EIE83255.1 - 0.1 12.1 2.2 1.4 8.3 0.3 2.9 2 2 2 4 4 4 0 Conserved hypothetical ATP binding protein NACHT PF05729.7 EIE83255.1 - 0.11 12.2 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.1 EIE83255.1 - 0.16 11.8 0.8 0.33 10.8 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain DUF3987 PF13148.1 EIE83255.1 - 0.2 10.1 3.5 0.25 9.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Dynamin_N PF00350.18 EIE83255.1 - 0.22 11.3 9.2 0.31 10.8 0.1 3.2 3 1 1 4 4 4 0 Dynamin family DivIC PF04977.10 EIE83255.1 - 0.34 10.4 5.0 1.1 8.8 0.4 2.5 2 0 0 2 2 2 0 Septum formation initiator PP-binding PF00550.20 EIE83256.1 - 4.7e-14 52.4 0.1 5.9e-14 52.0 0.1 1.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 EIE83256.1 - 5e-07 29.6 0.2 6.1e-07 29.3 0.2 1.2 1 0 0 1 1 1 1 Acyl-carrier DUF1493 PF07377.7 EIE83256.1 - 0.042 13.9 0.1 0.055 13.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) HLH PF00010.21 EIE83257.1 - 1.6e-11 43.7 1.9 1.8e-11 43.5 0.2 2.0 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain Vps16_C PF04840.7 EIE83259.1 - 8.2e-81 271.4 4.7 1.4e-79 267.3 2.0 2.3 1 1 1 2 2 2 2 Vps16, C-terminal region Vps16_N PF04841.8 EIE83259.1 - 3.3e-68 230.1 0.0 4.6e-68 229.6 0.0 1.2 1 0 0 1 1 1 1 Vps16, N-terminal region ODR4-like PF14778.1 EIE83259.1 - 0.0037 16.0 0.2 0.0071 15.0 0.1 1.4 1 0 0 1 1 1 1 Olfactory receptor 4-like DUF1476 PF07345.6 EIE83259.1 - 0.018 15.2 2.8 0.14 12.4 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1476) PRANC PF09372.5 EIE83260.1 - 0.029 14.3 1.9 0.14 12.1 1.0 1.9 1 1 1 2 2 2 0 PRANC domain T4SS PF07996.6 EIE83261.1 - 0.061 13.1 0.4 0.07 12.9 0.3 1.2 1 0 0 1 1 1 0 Type IV secretion system proteins DivIC PF04977.10 EIE83262.1 - 0.29 10.6 4.5 0.83 9.1 3.1 1.9 1 1 0 1 1 1 0 Septum formation initiator Chromo PF00385.19 EIE83264.1 - 2.1e-10 40.1 0.7 3.8e-10 39.2 0.5 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Cor1 PF04803.7 EIE83265.1 - 0.08 12.7 1.7 0.2 11.3 1.2 1.6 1 0 0 1 1 1 0 Cor1/Xlr/Xmr conserved region Chromo PF00385.19 EIE83266.1 - 9.5e-07 28.4 0.1 1.8e-06 27.5 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain YcgR_2 PF12945.2 EIE83266.1 - 0.0045 16.8 0.0 0.01 15.7 0.0 1.6 1 1 0 1 1 1 1 Flagellar protein YcgR Tudor-knot PF11717.3 EIE83266.1 - 0.03 14.0 0.6 0.071 12.8 0.4 1.6 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain rve PF00665.21 EIE83266.1 - 0.093 12.8 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Integrase core domain Retrotrans_gag PF03732.12 EIE83267.1 - 2.4e-05 24.3 0.1 6.2e-05 22.9 0.0 1.8 2 0 0 2 2 2 1 Retrotransposon gag protein FYDLN_acid PF09538.5 EIE83267.1 - 1.7 9.2 5.1 0.46 11.0 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (FYDLN_acid) rve PF00665.21 EIE83269.1 - 6.1e-19 68.2 0.0 1.6e-18 66.9 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 EIE83269.1 - 9.6e-14 50.8 1.8 2.9e-13 49.2 1.3 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Transposase_21 PF02992.9 EIE83271.1 - 2.9e-23 82.1 0.1 5.7e-23 81.1 0.1 1.4 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 EIE83271.1 - 3.9e-05 23.0 0.3 8.6e-05 21.9 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Lzipper-MIP1 PF14389.1 EIE83272.1 - 0.005 16.9 0.4 0.013 15.5 0.3 1.7 1 0 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 ChaB PF06150.7 EIE83272.1 - 0.069 12.9 0.6 0.25 11.1 0.1 2.2 2 0 0 2 2 2 0 ChaB IncA PF04156.9 EIE83272.1 - 0.17 11.4 1.2 0.28 10.7 0.9 1.4 1 0 0 1 1 1 0 IncA protein SRR PF07709.6 EIE83272.1 - 0.23 11.7 4.4 5.5 7.6 0.0 3.5 3 0 0 3 3 3 0 Seven Residue Repeat Transposase_21 PF02992.9 EIE83273.1 - 7.1e-22 77.6 0.0 1.3e-21 76.7 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 DUF1258 PF06869.7 EIE83273.1 - 0.0033 16.5 0.7 0.0044 16.1 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1258) DDE_3 PF13358.1 EIE83274.1 - 5.9e-15 55.2 0.1 1.1e-14 54.3 0.0 1.5 1 1 1 2 2 2 1 DDE superfamily endonuclease NDUF_B6 PF09782.4 EIE83274.1 - 0.08 12.7 0.6 0.2 11.5 0.2 1.6 1 1 1 2 2 2 0 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit Transposase_21 PF02992.9 EIE83275.1 - 1e-17 63.9 0.1 1.7e-17 63.2 0.0 1.4 2 0 0 2 2 2 1 Transposase family tnp2 DUF1258 PF06869.7 EIE83275.1 - 0.00099 18.2 0.0 0.0014 17.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) Med15 PF09606.5 EIE83276.1 - 0.023 12.9 10.8 0.032 12.4 7.5 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal FlgM PF04316.8 EIE83276.1 - 0.88 9.5 3.7 5.1 7.1 2.0 2.2 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM rve PF00665.21 EIE83277.1 - 8.7e-18 64.5 0.0 3.7e-17 62.5 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 EIE83277.1 - 4e-14 52.4 0.9 1e-13 51.1 0.6 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE83277.1 - 1.4e-06 27.8 1.3 5.6e-06 25.9 0.7 2.2 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.1 EIE83277.1 - 4.8e-05 23.7 0.1 0.00046 20.6 0.0 2.4 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.15 EIE83277.1 - 0.00057 19.7 0.1 0.0021 17.9 0.0 2.0 1 0 0 1 1 1 1 Retroviral aspartyl protease Tudor-knot PF11717.3 EIE83277.1 - 0.019 14.6 0.7 0.054 13.2 0.5 1.8 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain YcgR_2 PF12945.2 EIE83277.1 - 0.028 14.2 0.0 0.42 10.5 0.0 2.5 2 0 0 2 2 2 0 Flagellar protein YcgR gag-asp_proteas PF13975.1 EIE83277.1 - 0.07 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease HTH_Tnp_Tc3_2 PF01498.13 EIE83279.1 - 6.3e-11 42.1 0.9 6.3e-11 42.1 0.6 1.8 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.1 EIE83279.1 - 0.0025 17.3 0.3 0.0074 15.9 0.0 1.9 2 0 0 2 2 2 1 Homeodomain-like domain HTH_30 PF13556.1 EIE83279.1 - 0.012 15.2 0.0 0.12 12.0 0.0 2.1 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain HTH_29 PF13551.1 EIE83279.1 - 0.013 15.5 0.3 0.031 14.4 0.0 1.7 2 0 0 2 2 2 0 Winged helix-turn helix DDE_3 PF13358.1 EIE83279.1 - 0.014 15.1 0.0 0.029 14.1 0.0 1.6 1 0 0 1 1 1 0 DDE superfamily endonuclease FNIP_C PF14638.1 EIE83279.1 - 0.068 12.5 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Folliculin-interacting protein C-terminus RecX PF02631.11 EIE83279.1 - 0.072 13.2 0.1 0.11 12.6 0.1 1.3 1 0 0 1 1 1 0 RecX family CENP-F_leu_zip PF10473.4 EIE83280.1 - 0.0037 17.1 0.6 0.0037 17.1 0.4 1.5 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2968 PF11180.3 EIE83280.1 - 0.0057 16.0 0.5 0.0057 16.0 0.4 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2968) Spectrin PF00435.16 EIE83280.1 - 0.021 15.1 0.6 0.076 13.3 0.0 2.0 2 0 0 2 2 2 0 Spectrin repeat Pyridox_oxase_2 PF12766.2 EIE83280.1 - 0.06 13.6 0.1 0.14 12.4 0.1 1.7 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase DUF904 PF06005.7 EIE83280.1 - 0.84 9.9 7.1 0.33 11.2 1.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF904) RVT_1 PF00078.22 EIE83283.1 - 8.5e-31 106.9 0.0 1.5e-29 102.9 0.0 2.2 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 EIE83284.1 - 1.1e-08 35.3 0.1 1.1e-07 32.2 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.1 EIE83284.1 - 2.4e-06 27.2 0.1 5.3e-06 26.1 0.1 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 EIE83284.1 - 0.065 13.1 0.0 0.19 11.6 0.0 1.8 1 0 0 1 1 1 0 Retroviral aspartyl protease Retrotrans_gag PF03732.12 EIE83287.1 - 0.00035 20.5 0.0 0.00061 19.8 0.0 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein FYDLN_acid PF09538.5 EIE83287.1 - 0.079 13.5 0.2 0.16 12.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) rve PF00665.21 EIE83288.1 - 1.1e-18 67.4 0.0 2.5e-18 66.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE83288.1 - 2.1e-16 59.9 0.4 4.8e-16 58.7 0.1 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE83288.1 - 8.8e-14 50.9 2.2 2.4e-13 49.5 1.5 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DDE_3 PF13358.1 EIE83289.1 - 6.5e-18 64.8 0.3 2.9e-17 62.7 0.0 2.2 3 0 0 3 3 3 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE83289.1 - 2.1e-11 43.7 0.3 7.9e-11 41.8 0.3 2.0 2 0 0 2 2 2 1 Transposase HTH_Tnp_Tc3_2 PF01498.13 EIE83290.1 - 5.7e-10 39.1 2.4 3.8e-09 36.4 0.9 2.4 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.1 EIE83290.1 - 6.6e-10 38.9 0.2 3.3e-07 30.1 0.3 2.3 1 1 1 2 2 2 2 DDE superfamily endonuclease HTH_11 PF08279.7 EIE83290.1 - 0.00055 19.5 0.0 0.0014 18.2 0.0 1.6 1 0 0 1 1 1 1 HTH domain HTH_IclR PF09339.5 EIE83290.1 - 0.00059 19.3 0.0 0.0012 18.4 0.0 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_23 PF13384.1 EIE83290.1 - 0.00075 19.0 1.9 0.0008 18.9 0.0 1.9 2 0 0 2 2 2 1 Homeodomain-like domain HTH_7 PF02796.10 EIE83290.1 - 0.0019 18.0 0.2 0.046 13.5 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_32 PF13565.1 EIE83290.1 - 0.0025 18.5 0.7 2.4 9.0 0.0 2.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.1 EIE83290.1 - 0.0044 17.1 0.1 0.031 14.4 0.0 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_38 PF13936.1 EIE83290.1 - 0.0058 16.1 0.0 0.012 15.0 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_36 PF13730.1 EIE83290.1 - 0.0066 16.5 0.3 0.19 11.8 0.0 3.0 3 0 0 3 3 3 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.7 EIE83290.1 - 0.012 15.0 0.0 0.024 14.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_AsnC-type PF13404.1 EIE83290.1 - 0.012 15.1 0.0 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_17 PF12728.2 EIE83290.1 - 0.026 14.7 0.0 0.056 13.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain UPF0122 PF04297.9 EIE83290.1 - 0.029 14.3 0.1 0.069 13.1 0.0 1.6 1 0 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like HTH_24 PF13412.1 EIE83290.1 - 0.031 13.6 0.0 0.073 12.4 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Sigma70_r4 PF04545.11 EIE83290.1 - 0.036 13.3 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 Terminase_5 PF06056.7 EIE83290.1 - 0.041 13.4 0.0 0.091 12.3 0.0 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) GerE PF00196.14 EIE83290.1 - 0.07 12.4 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family HTH_Tnp_4 PF13613.1 EIE83290.1 - 0.11 12.0 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_6 PF01418.12 EIE83290.1 - 0.15 11.7 0.0 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family DUF2652 PF10851.3 EIE83292.1 - 0.14 12.1 0.0 0.16 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2652) NAP PF00956.13 EIE83294.1 - 4e-84 281.5 10.3 4e-84 281.5 7.1 2.0 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Nucleoplasmin PF03066.10 EIE83294.1 - 4.8 6.6 35.2 1.5 8.3 2.7 3.2 3 0 0 3 3 3 0 Nucleoplasmin ATP-synt_C PF00137.16 EIE83295.1 - 1.7e-28 98.3 32.3 6.6e-16 57.9 7.0 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Asp PF00026.18 EIE83296.1 - 5.6e-49 167.0 2.1 1.1e-48 166.1 1.5 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIE83296.1 - 2.5e-06 27.5 2.6 8.6e-06 25.8 1.8 2.0 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Arm PF00514.18 EIE83297.1 - 2.2e-27 93.8 9.8 1.3e-06 28.0 0.3 8.1 8 0 0 8 8 8 6 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EIE83297.1 - 1.9e-13 50.4 2.5 0.00023 21.3 0.0 4.9 2 2 1 3 3 3 3 HEAT repeats HEAT PF02985.17 EIE83297.1 - 8.9e-10 37.8 7.8 0.0051 16.7 0.1 6.7 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.1 EIE83297.1 - 1.6e-07 31.6 3.0 1.7 9.2 0.1 5.6 4 2 1 5 5 5 3 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EIE83297.1 - 3.2e-05 24.2 2.0 0.15 12.4 0.1 3.3 3 0 0 3 3 3 2 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 EIE83297.1 - 0.00083 17.7 10.4 0.0011 17.3 1.5 3.0 1 1 2 3 3 3 1 Adaptin N terminal region Vps39_1 PF10366.4 EIE83297.1 - 0.041 13.8 0.6 0.24 11.4 0.1 2.3 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 DUF3361 PF11841.3 EIE83297.1 - 0.059 13.0 4.0 2.9 7.5 0.0 3.7 3 1 2 5 5 5 0 Domain of unknown function (DUF3361) S10_plectin PF03501.10 EIE83298.1 - 1.4e-42 143.4 0.0 1.6e-42 143.2 0.0 1.1 1 0 0 1 1 1 1 Plectin/S10 domain TrmB PF01978.14 EIE83298.1 - 0.1 12.2 0.0 0.28 10.9 0.0 1.6 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB DUF2250 PF10007.4 EIE83298.1 - 0.17 11.8 1.0 13 5.8 0.3 2.3 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) ABC_membrane_2 PF06472.10 EIE83299.1 - 0.0021 17.2 1.0 0.09 11.8 0.0 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region 2 Mer2 PF09074.5 EIE83299.1 - 0.0074 16.2 8.4 0.0074 16.2 5.8 3.4 2 1 1 3 3 3 1 Mer2 Ribosomal_L16 PF00252.13 EIE83300.1 - 9.6e-34 116.0 0.1 1.2e-33 115.7 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Velvet PF11754.3 EIE83301.1 - 2.9e-17 62.9 1.8 3.8e-10 39.7 0.3 2.1 1 1 1 2 2 2 2 Velvet factor Rad60-SLD PF11976.3 EIE83301.1 - 0.035 13.7 0.0 0.066 12.9 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2415 PF10313.4 EIE83302.1 - 8.9e-16 57.2 0.3 2.5e-13 49.4 0.1 2.6 2 0 0 2 2 2 2 Uncharacterised protein domain (DUF2415) WD40 PF00400.27 EIE83302.1 - 1.2e-09 37.7 3.8 0.00014 21.5 0.2 4.8 6 0 0 6 6 6 2 WD domain, G-beta repeat Lgl_C PF08596.5 EIE83302.1 - 0.0012 17.3 0.0 0.0058 15.1 0.0 1.9 2 0 0 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal Coatomer_WDAD PF04053.9 EIE83302.1 - 0.023 13.5 0.0 0.032 13.0 0.0 1.2 1 0 0 1 1 1 0 Coatomer WD associated region BBS2_Mid PF14783.1 EIE83302.1 - 0.041 13.6 0.1 5.9 6.7 0.0 2.6 2 1 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Ribosomal_S4e PF00900.15 EIE83303.1 - 3.5e-33 113.1 2.1 7e-33 112.1 0.6 2.1 2 0 0 2 2 2 1 Ribosomal family S4e RS4NT PF08071.7 EIE83303.1 - 1.5e-19 69.5 5.5 1.4e-18 66.3 4.6 2.0 2 0 0 2 2 2 1 RS4NT (NUC023) domain S4 PF01479.20 EIE83303.1 - 3.3e-06 26.4 0.0 7.1e-06 25.3 0.0 1.6 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 EIE83303.1 - 0.00043 19.8 2.2 0.00043 19.8 1.5 3.5 4 0 0 4 4 4 1 KOW motif Pkinase PF00069.20 EIE83304.1 - 7.3e-63 212.1 0.0 1e-62 211.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE83304.1 - 9.5e-47 159.2 0.0 1.4e-46 158.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE83304.1 - 6e-05 22.1 0.0 0.00014 20.9 0.0 1.6 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EIE83304.1 - 0.24 11.1 0.0 0.43 10.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF2410 PF10307.4 EIE83305.1 - 1.5e-39 135.4 0.0 3.5e-39 134.2 0.0 1.6 1 1 0 1 1 1 1 Hypothetical protein (DUF2410) AA_permease_2 PF13520.1 EIE83306.1 - 5.6e-53 180.0 52.4 7.2e-53 179.6 36.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EIE83306.1 - 1.9e-36 125.4 45.7 2.6e-36 124.9 31.7 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.1 EIE83306.1 - 3e-07 30.2 6.6 3e-07 30.2 4.5 4.2 3 0 0 3 3 3 1 C-terminus of AA_permease adh_short PF00106.20 EIE83307.1 - 6.4e-07 29.4 0.5 0.00036 20.4 0.3 2.1 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.5 EIE83307.1 - 0.065 12.9 0.2 0.074 12.7 0.1 1.2 1 1 0 1 1 1 0 KR domain Glyco_hydro_9 PF00759.14 EIE83308.1 - 9.6e-23 80.7 0.3 1.4e-11 44.0 0.5 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 9 Glyco_hydro_9 PF00759.14 EIE83309.1 - 2.1e-16 59.8 0.0 2.7e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 ABC2_membrane_3 PF12698.2 EIE83309.1 - 0.045 12.7 0.2 0.057 12.4 0.1 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein CcmH PF03918.9 EIE83309.1 - 0.062 12.2 0.0 0.096 11.6 0.0 1.3 1 0 0 1 1 1 0 Cytochrome C biogenesis protein Aminotran_1_2 PF00155.16 EIE83310.1 - 1e-84 284.5 0.0 1.2e-84 284.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II E1_dh PF00676.15 EIE83311.1 - 9.1e-94 313.5 0.0 1.3e-93 313.0 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Acyl-CoA_dh_1 PF00441.19 EIE83311.1 - 7.5e-40 136.4 0.2 1.2e-39 135.7 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.23 EIE83311.1 - 3.8e-23 81.0 0.1 1e-22 79.6 0.1 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.14 EIE83311.1 - 6.8e-21 73.5 0.2 1.3e-20 72.6 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EIE83311.1 - 5.8e-17 62.2 0.0 2.6e-16 60.1 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Transketolase_N PF00456.16 EIE83311.1 - 1.1e-06 27.7 0.2 2.3e-06 26.6 0.2 1.5 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Acyl-CoA_dh_2 PF08028.6 EIE83311.1 - 1.6e-05 25.1 0.0 4.6e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DXP_synthase_N PF13292.1 EIE83311.1 - 0.037 12.9 0.0 0.14 11.1 0.0 1.8 1 1 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase PPO1_DWL PF12142.3 EIE83311.1 - 0.089 12.3 3.5 0.069 12.6 0.6 2.1 2 0 0 2 2 2 0 Polyphenol oxidase middle domain Ank_2 PF12796.2 EIE83312.1 - 1.8e-15 57.0 0.5 3.9e-15 55.9 0.3 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) ArfGap PF01412.13 EIE83312.1 - 1.6e-13 50.4 0.8 5.8e-08 32.5 0.2 2.8 1 1 1 2 2 2 2 Putative GTPase activating protein for Arf Ank_4 PF13637.1 EIE83312.1 - 3.6e-12 46.4 0.2 1.8e-07 31.4 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) PH PF00169.24 EIE83312.1 - 7.3e-10 38.9 0.2 1.4e-09 38.1 0.1 1.5 1 0 0 1 1 1 1 PH domain Ank PF00023.25 EIE83312.1 - 3.7e-09 35.9 1.9 0.00023 20.7 0.3 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 EIE83312.1 - 1.3e-08 34.2 0.4 0.00033 20.6 0.1 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EIE83312.1 - 7.1e-07 29.2 0.7 4.5e-06 26.7 0.1 2.7 1 1 2 3 3 3 2 Ankyrin repeats (many copies) PH_8 PF15409.1 EIE83312.1 - 0.00049 20.1 0.1 0.0012 18.8 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 EIE83312.1 - 0.011 16.0 2.6 0.35 11.1 0.7 3.2 2 1 0 2 2 2 0 Pleckstrin homology domain Arf PF00025.16 EIE83313.1 - 5.2e-65 217.9 0.3 6.2e-65 217.6 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EIE83313.1 - 5.7e-11 41.9 0.2 6.9e-11 41.6 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EIE83313.1 - 7.5e-10 38.4 0.1 9.5e-10 38.0 0.1 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EIE83313.1 - 2.9e-09 36.4 0.3 4.4e-09 35.8 0.2 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EIE83313.1 - 2.9e-08 34.2 0.1 4.2e-08 33.7 0.1 1.3 1 0 0 1 1 1 1 Miro-like protein G-alpha PF00503.15 EIE83313.1 - 1.5e-07 30.4 0.8 0.0019 16.9 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.18 EIE83313.1 - 0.0002 21.2 0.2 0.00044 20.2 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EIE83313.1 - 0.00033 20.1 0.3 0.0069 15.8 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 EIE83313.1 - 0.0097 16.2 0.7 0.034 14.4 0.5 1.8 1 1 0 1 1 1 1 ABC transporter ArgK PF03308.11 EIE83313.1 - 0.0098 14.6 0.9 0.48 9.1 0.2 2.7 2 1 0 2 2 2 1 ArgK protein cobW PF02492.14 EIE83313.1 - 0.012 15.0 1.4 2.1 7.7 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 EIE83313.1 - 0.032 13.8 0.8 6.1 6.4 0.0 2.1 1 1 0 2 2 2 0 NACHT domain AAA_18 PF13238.1 EIE83313.1 - 0.1 12.9 0.6 0.15 12.3 0.4 1.4 1 1 0 1 1 1 0 AAA domain Methyltransf_11 PF08241.7 EIE83314.1 - 2.6e-09 37.4 0.0 1.8e-08 34.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIE83314.1 - 3.3e-09 36.6 0.0 4.6e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIE83314.1 - 9.6e-09 34.9 0.0 3.8e-07 29.8 0.0 2.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIE83314.1 - 0.00062 20.0 0.0 0.083 13.2 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIE83314.1 - 0.0022 18.5 0.0 0.0066 17.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain PK PF00224.16 EIE83315.1 - 7.7e-166 550.9 3.6 9.6e-166 550.6 2.5 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 EIE83315.1 - 1.7e-31 108.2 0.1 1.1e-30 105.5 0.0 2.4 3 0 0 3 3 3 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 EIE83315.1 - 4.1e-06 25.8 0.2 7.8e-06 24.9 0.1 1.5 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.20 EIE83315.1 - 0.016 14.1 0.6 0.11 11.4 0.0 2.1 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain AAA_19 PF13245.1 EIE83315.1 - 0.12 12.1 1.6 0.29 10.9 0.1 2.4 3 0 0 3 3 3 0 Part of AAA domain Ribosomal_L36e PF01158.13 EIE83316.1 - 1.3e-38 130.8 5.7 1.5e-38 130.7 3.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e LemA PF04011.7 EIE83316.1 - 0.0011 18.1 0.1 0.0011 18.0 0.1 1.1 1 0 0 1 1 1 1 LemA family 4HB_MCP_1 PF12729.2 EIE83316.1 - 0.015 14.6 0.1 0.018 14.4 0.0 1.1 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction priB_priC PF07445.7 EIE83316.1 - 0.016 14.6 0.1 0.018 14.4 0.1 1.1 1 0 0 1 1 1 0 Primosomal replication protein priB and priC PINIT PF14324.1 EIE83317.1 - 2.7e-10 40.5 0.6 4.4e-10 39.8 0.1 1.5 2 0 0 2 2 2 1 PINIT domain WD40 PF00400.27 EIE83318.1 - 3.6e-56 185.1 20.3 2.6e-09 36.6 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Sugar_tr PF00083.19 EIE83319.1 - 7.1e-109 364.3 32.2 8e-80 268.6 16.0 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EIE83319.1 - 5.7e-26 91.0 37.7 4.1e-24 84.9 17.3 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily PSI PF01437.20 EIE83319.1 - 0.00085 19.4 4.7 0.0016 18.5 3.2 1.4 1 0 0 1 1 1 1 Plexin repeat AMMECR1 PF01871.12 EIE83322.1 - 2.4e-43 147.2 0.0 4.6e-43 146.3 0.0 1.4 1 0 0 1 1 1 1 AMMECR1 BSD PF03909.12 EIE83322.1 - 0.00042 19.9 1.3 0.00042 19.9 0.9 3.5 3 0 0 3 3 3 1 BSD domain Mut7-C PF01927.11 EIE83322.1 - 0.0049 16.8 1.1 0.01 15.8 0.7 1.5 1 0 0 1 1 1 1 Mut7-C RNAse domain DUF572 PF04502.8 EIE83322.1 - 0.22 10.6 21.8 0.31 10.1 15.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF1681 PF07933.9 EIE83323.1 - 3.1e-14 52.8 0.1 3.1e-14 52.8 0.1 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1681) CotH PF08757.6 EIE83324.1 - 9.5e-33 113.7 5.8 1.7e-32 112.9 4.0 1.3 1 0 0 1 1 1 1 CotH protein RNA_pol_Rpb2_6 PF00562.23 EIE83325.1 - 6.4e-116 387.2 1.6 8.5e-116 386.8 1.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EIE83325.1 - 2.2e-30 105.1 0.0 3.2e-30 104.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.11 EIE83325.1 - 5.5e-24 83.7 0.0 1.3e-23 82.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.7 EIE83325.1 - 3.6e-23 81.2 0.0 6.9e-23 80.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.15 EIE83325.1 - 3.3e-21 75.3 0.0 7.2e-21 74.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.9 EIE83325.1 - 7.3e-20 71.1 0.0 1.3e-19 70.3 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_5 PF04567.12 EIE83325.1 - 0.00074 19.4 0.0 0.0017 18.2 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Sin_N PF04801.8 EIE83326.1 - 1.3e-23 83.5 2.5 2.4e-23 82.6 1.7 1.4 1 1 0 1 1 1 1 Sin-like protein conserved region ATP-synt_E PF05680.7 EIE83326.1 - 7.6 6.5 11.8 3.7 7.5 4.4 2.2 2 0 0 2 2 2 0 ATP synthase E chain Gp_dh_C PF02800.15 EIE83328.1 - 1.7e-74 248.5 0.0 2.5e-74 247.9 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 EIE83328.1 - 3.3e-59 199.1 0.7 7.4e-59 198.0 0.1 1.9 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 EIE83328.1 - 0.032 14.1 0.3 0.3 11.0 0.0 2.4 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Thiolase_C PF02803.13 EIE83329.1 - 3.9e-12 45.6 0.0 2.7e-11 42.9 0.0 2.3 2 0 0 2 2 2 1 Thiolase, C-terminal domain Thiolase_N PF00108.18 EIE83329.1 - 7.2e-10 38.2 0.4 2.9e-09 36.3 0.1 1.9 2 1 0 3 3 3 1 Thiolase, N-terminal domain ketoacyl-synt PF00109.21 EIE83329.1 - 3.3e-05 23.4 3.9 0.00031 20.3 2.1 2.6 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EIE83329.1 - 0.00022 21.0 0.0 0.13 12.1 0.0 3.3 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain ACP_syn_III PF08545.5 EIE83329.1 - 0.00026 20.6 1.1 0.011 15.4 0.2 3.0 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III HMG_CoA_synt_N PF01154.12 EIE83329.1 - 0.0022 17.5 0.1 0.0042 16.6 0.1 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal SpoVAD PF07451.6 EIE83329.1 - 0.0048 15.3 0.4 0.53 8.6 0.1 2.2 2 0 0 2 2 2 2 Stage V sporulation protein AD (SpoVAD) CHAP PF05257.11 EIE83329.1 - 0.022 14.4 0.1 0.74 9.4 0.0 2.5 2 0 0 2 2 2 0 CHAP domain DUF3808 PF10300.4 EIE83330.1 - 7.4e-75 252.2 7.0 7.4e-51 173.1 1.6 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3808) TPR_12 PF13424.1 EIE83330.1 - 0.0025 17.6 0.2 0.0025 17.6 0.1 3.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 EIE83330.1 - 0.014 15.1 1.1 0.078 12.7 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Kin17_mid PF10357.4 EIE83332.1 - 3.7e-46 155.8 0.7 5.7e-46 155.2 0.5 1.3 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.3 EIE83332.1 - 0.00056 19.9 7.2 0.0012 18.9 5.0 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EIE83332.1 - 0.0033 17.5 5.2 0.0067 16.5 3.6 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EIE83332.1 - 0.0036 17.3 1.3 0.0036 17.3 0.9 1.8 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) DUF427 PF04248.7 EIE83332.1 - 0.013 15.1 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF427) MC1 PF05854.6 EIE83332.1 - 0.019 14.8 1.0 2 8.4 0.0 2.6 2 1 0 2 2 2 0 Non-histone chromosomal protein MC1 Homoserine_dh PF00742.14 EIE83333.1 - 7.4e-36 123.4 0.0 3.5e-35 121.2 0.0 1.9 1 1 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 EIE83333.1 - 3.5e-16 59.6 0.0 6e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 EIE83333.1 - 0.00035 20.8 0.0 0.0009 19.5 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 EIE83333.1 - 0.031 14.1 0.0 0.085 12.7 0.0 1.7 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus F420_oxidored PF03807.12 EIE83333.1 - 0.038 14.4 0.1 0.13 12.6 0.1 1.9 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NIF PF03031.13 EIE83334.1 - 5e-38 130.2 1.0 2.7e-36 124.6 0.7 2.2 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase FMN_dh PF01070.13 EIE83335.1 - 1.3e-106 356.5 0.5 6.8e-69 232.3 0.1 2.1 1 1 1 2 2 2 2 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EIE83335.1 - 5e-26 90.3 0.0 1e-25 89.2 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 EIE83335.1 - 1.6e-08 33.8 0.0 2.9e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 EIE83335.1 - 0.00039 19.4 0.1 0.00085 18.3 0.1 1.4 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 EIE83335.1 - 0.078 12.1 0.1 0.11 11.5 0.1 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase DUF2063 PF09836.4 EIE83335.1 - 0.089 12.7 0.0 0.31 11.0 0.0 1.9 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2063) ThiG PF05690.9 EIE83335.1 - 0.12 11.3 0.1 6.8 5.6 0.0 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG PGK PF00162.14 EIE83336.1 - 8.5e-152 505.1 0.2 9.6e-152 504.9 0.2 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase Transposase_21 PF02992.9 EIE83337.1 - 5.5e-22 77.9 0.1 5.5e-22 77.9 0.1 1.6 2 0 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.1 EIE83337.1 - 9.3e-05 21.8 0.1 0.00021 20.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Lzipper-MIP1 PF14389.1 EIE83338.1 - 0.00068 19.6 0.3 0.0019 18.2 0.2 1.7 1 0 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 IncA PF04156.9 EIE83338.1 - 0.02 14.4 2.1 0.026 14.1 1.5 1.3 1 0 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 EIE83338.1 - 0.04 11.7 3.4 0.047 11.5 2.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family UPF0242 PF06785.6 EIE83338.1 - 0.06 12.0 3.4 0.071 11.7 1.9 1.2 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) DUF1451 PF07295.6 EIE83338.1 - 0.17 11.6 4.2 0.36 10.5 2.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1451) DUF1002 PF06207.6 EIE83338.1 - 0.8 8.9 6.9 0.094 12.0 1.4 1.8 1 1 0 2 2 2 0 Protein of unknown function (DUF1002) DivIC PF04977.10 EIE83338.1 - 1.8 8.0 8.2 1.2 8.6 1.0 2.4 2 0 0 2 2 2 0 Septum formation initiator DUF972 PF06156.8 EIE83338.1 - 7.1 7.0 10.1 1.1 9.6 3.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Fib_alpha PF08702.5 EIE83338.1 - 9.4 6.3 8.0 2.1 8.4 2.5 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Rod_C PF10493.4 EIE83339.1 - 0.019 13.2 0.1 0.027 12.8 0.0 1.1 1 0 0 1 1 1 0 Rough deal protein C-terminal region Ras PF00071.17 EIE83340.1 - 7.7e-19 67.6 0.0 9.1e-19 67.4 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIE83340.1 - 1.8e-07 31.6 0.1 3.8e-07 30.6 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EIE83340.1 - 0.0067 15.6 0.1 0.0079 15.4 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family PNK3P PF08645.6 EIE83340.1 - 0.057 12.8 0.0 0.073 12.5 0.0 1.1 1 0 0 1 1 1 0 Polynucleotide kinase 3 phosphatase DUF3126 PF11324.3 EIE83341.1 - 0.051 13.2 0.0 0.088 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3126) TBCA PF02970.11 EIE83342.1 - 0.055 13.5 2.3 0.71 9.9 0.1 2.8 1 1 1 2 2 2 0 Tubulin binding cofactor A DUF739 PF05339.6 EIE83343.1 - 0.05 13.4 0.2 0.13 12.1 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF739) TFIIF_alpha PF05793.7 EIE83344.1 - 0.013 13.8 43.2 0.016 13.6 30.0 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Raftlin PF15250.1 EIE83344.1 - 3.5 6.0 8.4 4 5.8 5.8 1.3 1 0 0 1 1 1 0 Raftlin MIP-T3 PF10243.4 EIE83344.1 - 8 4.8 35.3 9.8 4.5 24.5 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 YTH PF04146.10 EIE83345.1 - 6.3e-15 55.0 1.3 6.3e-15 55.0 0.9 1.9 2 0 0 2 2 2 1 YT521-B-like domain Smg4_UPF3 PF03467.10 EIE83345.1 - 0.011 15.7 0.6 0.039 13.9 0.4 1.9 1 0 0 1 1 1 0 Smg-4/UPF3 family MFS_1 PF07690.11 EIE83346.1 - 1.1e-17 63.7 53.7 1.6e-13 50.1 19.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EIE83346.1 - 1.1e-08 33.9 13.9 1.1e-08 33.9 9.6 1.8 2 0 0 2 2 2 1 MFS/sugar transport protein Sugar_tr PF00083.19 EIE83346.1 - 9.1e-05 21.2 26.6 0.02 13.4 11.1 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter DUF2427 PF10348.4 EIE83346.1 - 0.026 14.1 4.1 0.045 13.3 1.8 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF2427) EcsB PF05975.7 EIE83346.1 - 0.43 8.9 9.0 0.19 10.1 1.7 2.3 1 1 1 2 2 2 0 Bacterial ABC transporter protein EcsB Endonuclease_NS PF01223.18 EIE83347.1 - 8.3e-30 103.9 0.0 9.3e-30 103.8 0.0 1.0 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease DUF603 PF04645.7 EIE83349.1 - 0.013 15.4 0.4 0.015 15.2 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF603 DASH_Dam1 PF08653.5 EIE83349.1 - 0.058 13.1 2.5 0.15 11.8 0.8 1.9 1 1 1 2 2 2 0 DASH complex subunit Dam1 zf-RVT PF13966.1 EIE83350.1 - 0.004 17.4 1.8 0.0061 16.8 0.7 1.8 1 1 0 1 1 1 1 zinc-binding in reverse transcriptase RVT_1 PF00078.22 EIE83351.1 - 1.8e-31 109.1 0.2 3.2e-31 108.3 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EIE83351.1 - 1.1e-08 34.7 0.0 5.8e-08 32.3 0.0 2.2 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EIE83351.1 - 0.00014 21.9 0.3 0.00023 21.1 0.2 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Dict-STAT-coil PF09267.5 EIE83351.1 - 0.0028 17.8 0.4 0.0061 16.7 0.3 1.5 1 0 0 1 1 1 1 Dictyostelium STAT, coiled coil zf-CCHC_6 PF15288.1 EIE83352.1 - 2.1e-05 24.0 3.1 0.054 13.1 0.7 2.7 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC PF00098.18 EIE83352.1 - 4.1e-05 23.3 14.9 0.00024 20.8 1.9 3.5 3 0 0 3 3 3 2 Zinc knuckle NMD3 PF04981.8 EIE83352.1 - 0.019 14.0 2.2 0.02 14.0 0.3 1.8 2 0 0 2 2 2 0 NMD3 family zf-CCHC_4 PF14392.1 EIE83352.1 - 3.4 7.4 14.8 2.8 7.6 0.8 3.2 3 0 0 3 3 3 0 Zinc knuckle zf-CCHC PF00098.18 EIE83353.1 - 1.8e-10 40.2 8.0 1.2e-05 24.9 0.3 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 EIE83353.1 - 0.0031 17.1 6.6 0.047 13.3 0.3 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.1 EIE83353.1 - 1.3 8.5 4.5 0.75 9.3 0.3 2.3 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC_6 PF15288.1 EIE83353.1 - 1.6 8.4 8.2 0.078 12.6 1.2 2.1 1 1 1 2 2 2 0 Zinc knuckle zf-RVT PF13966.1 EIE83354.1 - 4e-07 30.2 6.0 4e-07 30.2 4.2 2.3 2 1 0 2 2 2 1 zinc-binding in reverse transcriptase RVT_1 PF00078.22 EIE83355.1 - 1.2e-06 28.0 0.0 2.3e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PIF1 PF05970.9 EIE83357.1 - 4.6e-77 259.4 0.0 1.3e-56 192.1 0.0 2.2 1 1 1 2 2 2 2 PIF1-like helicase Herpes_Helicase PF02689.9 EIE83357.1 - 1.5e-06 26.3 0.1 3.2e-06 25.2 0.0 1.5 2 0 0 2 2 2 1 Helicase ResIII PF04851.10 EIE83357.1 - 3.3e-05 23.8 0.0 6.6e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 EIE83357.1 - 0.00077 19.0 0.0 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EIE83357.1 - 0.0016 18.1 0.0 0.0032 17.1 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 EIE83357.1 - 0.0025 17.5 0.0 0.0082 15.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) UvrD_C_2 PF13538.1 EIE83357.1 - 0.0037 17.3 0.0 0.0083 16.2 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain DAP3 PF10236.4 EIE83357.1 - 0.0061 15.5 0.0 0.011 14.7 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 TrwB_AAD_bind PF10412.4 EIE83357.1 - 0.013 14.1 0.0 0.023 13.3 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain PhoH PF02562.11 EIE83357.1 - 0.025 13.8 0.0 0.04 13.1 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein T2SE PF00437.15 EIE83357.1 - 0.056 12.3 0.0 0.091 11.6 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.1 EIE83357.1 - 0.063 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EIE83357.1 - 0.068 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.17 EIE83357.1 - 0.072 13.2 0.3 0.53 10.4 0.0 2.3 1 1 1 2 2 2 0 RNA helicase Helitron_like_N PF14214.1 EIE83359.1 - 3e-30 105.3 0.4 5e-30 104.6 0.3 1.3 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus DinB_2 PF12867.2 EIE83360.1 - 0.038 14.3 0.9 1 9.7 0.1 2.2 1 1 1 2 2 2 0 DinB superfamily DUF977 PF06163.6 EIE83362.1 - 0.096 12.4 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF977) CTP_transf_3 PF02348.14 EIE83363.1 - 0.09 12.3 1.3 0.13 11.8 0.9 1.3 1 0 0 1 1 1 0 Cytidylyltransferase DDE_3 PF13358.1 EIE83364.1 - 4.4e-21 75.1 0.0 6.1e-21 74.7 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.14 EIE83364.1 - 0.0059 15.7 0.0 0.023 13.8 0.0 1.9 1 1 0 1 1 1 1 DDE superfamily endonuclease ADH_N PF08240.7 EIE83365.1 - 3.1e-25 88.0 0.8 3.1e-25 88.0 0.6 1.9 2 0 0 2 2 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIE83365.1 - 9.4e-19 67.2 0.1 1.7e-18 66.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_7 PF13241.1 EIE83365.1 - 0.00081 19.6 0.0 0.0014 18.8 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding HI0933_like PF03486.9 EIE83365.1 - 0.001 17.6 0.1 0.0014 17.1 0.1 1.1 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 EIE83365.1 - 0.0011 19.3 0.2 0.0022 18.3 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_18 PF12847.2 EIE83365.1 - 0.0019 18.7 0.0 0.0046 17.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain DAO PF01266.19 EIE83365.1 - 0.004 16.1 0.1 0.0062 15.4 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase ADH_zinc_N_2 PF13602.1 EIE83365.1 - 0.0046 17.8 0.0 0.012 16.5 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.14 EIE83365.1 - 0.013 14.5 0.2 0.019 14.0 0.1 1.1 1 0 0 1 1 1 0 FAD binding domain NAD_binding_8 PF13450.1 EIE83365.1 - 0.035 14.1 0.2 0.11 12.4 0.0 1.9 2 0 0 2 2 1 0 NAD(P)-binding Rossmann-like domain XdhC_C PF13478.1 EIE83365.1 - 0.036 14.3 0.0 0.077 13.3 0.0 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain 2-Hacid_dh_C PF02826.14 EIE83365.1 - 0.05 12.7 0.1 0.091 11.9 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 EIE83365.1 - 0.058 13.0 0.1 0.12 12.0 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 EIE83365.1 - 0.068 13.1 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_2 PF07992.9 EIE83365.1 - 0.09 12.6 0.2 0.15 11.9 0.2 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Saccharop_dh PF03435.13 EIE83365.1 - 0.1 11.5 0.1 0.18 10.7 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase RrnaAD PF00398.15 EIE83365.1 - 0.14 11.1 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Ribosomal_L30 PF00327.15 EIE83366.1 - 1.9e-11 43.3 0.1 2.5e-11 42.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e FTHFS PF01268.14 EIE83367.1 - 1.9e-264 877.8 0.1 2.7e-264 877.3 0.0 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 EIE83367.1 - 1.8e-67 225.4 2.1 1.8e-67 225.4 1.5 1.9 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 EIE83367.1 - 2.4e-38 130.7 4.3 5.3e-38 129.6 3.0 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Adaptin_N PF01602.15 EIE83368.1 - 3.3e-137 458.0 3.8 3.8e-137 457.7 2.6 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 EIE83368.1 - 7.2e-08 32.7 0.2 1.9e-07 31.3 0.1 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.1 EIE83368.1 - 0.00028 21.1 0.4 0.26 11.6 0.1 4.5 3 3 1 4 4 4 1 HEAT repeats SPG48 PF14764.1 EIE83368.1 - 0.001 17.6 0.1 0.0068 14.9 0.0 2.1 2 0 0 2 2 2 1 AP-5 complex subunit, vesicle trafficking RIX1 PF08167.7 EIE83368.1 - 0.0023 17.6 0.1 0.05 13.2 0.0 2.9 1 1 1 3 3 3 1 rRNA processing/ribosome biogenesis Cnd1 PF12717.2 EIE83368.1 - 0.0061 16.4 4.2 0.48 10.2 0.1 3.3 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 ARS2 PF04959.8 EIE83368.1 - 0.035 14.2 0.0 0.074 13.2 0.0 1.5 1 0 0 1 1 1 0 Arsenite-resistance protein 2 TIP120 PF08623.5 EIE83368.1 - 0.056 13.0 0.4 0.19 11.3 0.1 2.1 2 0 0 2 2 2 0 TATA-binding protein interacting (TIP20) PNPase PF03726.9 EIE83368.1 - 0.096 12.9 0.0 4.1 7.7 0.0 2.6 2 0 0 2 2 2 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain LSM PF01423.17 EIE83370.1 - 1.2e-17 63.2 0.1 1.4e-17 62.9 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EIE83370.1 - 0.00018 21.3 0.1 0.00022 21.0 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain F_bP_aldolase PF01116.15 EIE83371.1 - 1.6e-99 332.6 0.0 1.8e-99 332.4 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II CPSase_L_D2 PF02786.12 EIE83371.1 - 0.1 11.8 0.6 0.7 9.1 0.4 2.0 1 1 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain Frag1 PF10277.4 EIE83373.1 - 2e-08 34.0 5.6 2.7e-06 27.0 0.3 4.9 4 2 1 5 5 5 3 Frag1/DRAM/Sfk1 family PAS_3 PF08447.6 EIE83374.1 - 0.33 11.0 1.6 5.9 7.0 0.6 2.0 1 1 1 2 2 2 0 PAS fold Zn_clus PF00172.13 EIE83376.1 - 1.5e-05 24.7 11.6 1.5e-05 24.7 8.0 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.19 EIE83376.1 - 0.00013 21.7 0.0 0.00024 20.8 0.0 1.5 1 0 0 1 1 1 1 PAS fold RE_NgoBV PF09564.5 EIE83376.1 - 0.13 11.4 0.0 0.25 10.5 0.0 1.4 1 0 0 1 1 1 0 NgoBV restriction endonuclease Collagen PF01391.13 EIE83377.1 - 0.022 14.2 20.5 0.082 12.4 14.2 1.9 1 1 0 1 1 1 0 Collagen triple helix repeat (20 copies) SNURF PF07192.6 EIE83377.1 - 0.76 9.6 7.0 44 4.0 0.0 4.6 1 1 4 5 5 5 0 SNURF/RPN4 protein Bromo_TP PF07524.8 EIE83377.1 - 7 6.4 16.6 6 6.6 0.2 4.9 5 0 0 5 5 5 0 Bromodomain associated Pyridox_oxidase PF01243.15 EIE83377.1 - 7.8 6.5 24.6 3.5 7.6 0.3 5.8 2 1 4 6 6 6 0 Pyridoxamine 5'-phosphate oxidase GATA PF00320.22 EIE83378.1 - 1.1e-16 59.8 4.3 1.8e-16 59.1 3.0 1.4 1 0 0 1 1 1 1 GATA zinc finger Cytochrom_c3_2 PF14537.1 EIE83378.1 - 0.075 13.3 3.4 1.4 9.2 2.3 2.4 1 1 0 1 1 1 0 Cytochrome c3 Cytochrome_C7 PF14522.1 EIE83378.1 - 0.25 10.9 2.9 0.86 9.2 0.4 2.3 2 0 0 2 2 2 0 Cytochrome c7 DDE_3 PF13358.1 EIE83379.1 - 2.3e-13 50.0 0.0 2.8e-13 49.8 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease EST1 PF10374.4 EIE83380.1 - 0.071 13.0 0.2 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 Telomerase activating protein Est1 F-box-like PF12937.2 EIE83381.1 - 6.4e-05 22.5 0.4 0.00012 21.6 0.3 1.5 1 0 0 1 1 1 1 F-box-like Fumarate_red_D PF02313.12 EIE83381.1 - 0.021 14.6 3.2 1.2 9.0 0.3 2.5 2 0 0 2 2 2 0 Fumarate reductase subunit D F-box PF00646.28 EIE83381.1 - 0.034 13.8 1.9 0.069 12.8 0.1 2.2 2 0 0 2 2 2 0 F-box domain RRM_1 PF00076.17 EIE83383.1 - 3.8e-14 52.0 0.0 1e-13 50.7 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE83383.1 - 2.9e-10 39.9 0.0 6.1e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE83383.1 - 1.4e-08 34.4 0.1 2.8e-08 33.4 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EST1 PF10374.4 EIE83383.1 - 1 9.3 5.0 14 5.7 3.3 2.9 1 1 0 1 1 1 0 Telomerase activating protein Est1 HC2 PF07382.6 EIE83383.1 - 1.2 8.9 32.1 0.17 11.7 17.0 2.2 2 0 0 2 2 2 0 Histone H1-like nucleoprotein HC2 Glyco_hydro_47 PF01532.15 EIE83384.1 - 4.8e-100 335.3 0.0 6.1e-100 334.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Methyltransf_11 PF08241.7 EIE83385.1 - 4.5e-06 27.0 0.0 7.8e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIE83385.1 - 0.0017 18.0 0.0 0.0031 17.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIE83385.1 - 0.01 16.4 0.0 0.028 14.9 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain CheR PF01739.13 EIE83385.1 - 0.066 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_12 PF08242.7 EIE83385.1 - 0.071 13.5 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Peroxin-22 PF12827.2 EIE83385.1 - 2.8 7.6 5.3 11 5.7 0.1 2.6 3 1 0 3 3 3 0 Peroxisomal biogenesis protein family PRELI PF04707.9 EIE83386.1 - 5.5e-27 94.2 0.3 6e-27 94.1 0.2 1.0 1 0 0 1 1 1 1 PRELI-like family M20_dimer PF07687.9 EIE83387.1 - 2.6e-09 36.8 0.0 6.1e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain SMP PF04927.7 EIE83388.1 - 0.0021 17.9 0.4 0.0028 17.5 0.2 1.2 1 0 0 1 1 1 1 Seed maturation protein TEX19 PF15553.1 EIE83389.1 - 0.027 14.3 2.9 0.026 14.4 1.2 1.6 1 1 0 1 1 1 0 Testis-expressed protein 19 Mod_r PF07200.8 EIE83389.1 - 0.29 11.0 27.0 0.059 13.2 5.3 3.8 1 1 2 4 4 4 0 Modifier of rudimentary (Mod(r)) protein bZIP_1 PF00170.16 EIE83389.1 - 0.39 10.7 22.6 0.3 11.0 1.5 4.7 4 1 1 5 5 5 0 bZIP transcription factor Img2 PF05046.9 EIE83391.1 - 6.4e-22 77.5 0.0 8e-22 77.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) SUI1 PF01253.17 EIE83391.1 - 0.00041 20.1 0.0 0.00048 19.8 0.0 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 Tic22 PF04278.7 EIE83391.1 - 0.061 12.5 0.0 0.072 12.3 0.0 1.0 1 0 0 1 1 1 0 Tic22-like family Usp PF00582.21 EIE83392.1 - 3.1e-12 46.8 0.2 6.4e-12 45.8 0.0 1.5 2 0 0 2 2 2 1 Universal stress protein family Chitin_synth_1 PF01644.12 EIE83394.1 - 3.1e-82 274.2 0.0 4.7e-82 273.6 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EIE83394.1 - 8.3e-32 108.7 0.1 2.7e-31 107.0 0.2 1.8 2 0 0 2 2 2 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EIE83394.1 - 6.1e-19 67.8 3.6 2.7e-17 62.3 0.0 2.2 1 1 0 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.1 EIE83394.1 - 1.9e-08 34.2 3.0 7.3e-08 32.3 2.1 2.0 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EIE83394.1 - 8.4e-06 25.7 0.0 1.7e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 DUF998 PF06197.8 EIE83394.1 - 0.0047 16.2 4.1 0.01 15.1 2.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF998) E1-E2_ATPase PF00122.15 EIE83395.1 - 3.9e-59 199.4 1.0 3.9e-59 199.4 0.7 3.0 4 1 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.21 EIE83395.1 - 1.8e-21 77.5 0.0 4.3e-21 76.3 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EIE83395.1 - 3.7e-14 51.9 0.0 9.6e-14 50.5 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EIE83395.1 - 2.3e-12 47.4 0.1 6.6e-12 45.9 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EIE83395.1 - 1.4e-05 24.8 1.1 2.4e-05 24.0 0.2 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Phospholamban PF04272.9 EIE83395.1 - 4.9 6.6 7.1 1.3 8.4 1.6 2.6 2 0 0 2 2 2 0 Phospholamban DUF2419 PF10343.4 EIE83396.1 - 6.4e-120 399.7 0.1 7.4e-120 399.5 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2419) Lon_C PF05362.8 EIE83397.1 - 2.7e-71 239.1 0.0 5.1e-71 238.2 0.0 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 EIE83397.1 - 1.9e-38 132.1 0.5 1.9e-38 132.1 0.3 2.3 3 1 0 3 3 3 1 ATP-dependent protease La (LON) domain AAA PF00004.24 EIE83397.1 - 1.4e-15 57.6 0.0 4.1e-15 56.1 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.1 EIE83397.1 - 5.1e-07 29.2 0.0 1e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.9 EIE83397.1 - 1.6e-06 27.9 0.0 3.6e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_PrkA PF08298.6 EIE83397.1 - 3.3e-05 22.7 0.0 6.7e-05 21.7 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain RuvB_N PF05496.7 EIE83397.1 - 3.8e-05 22.8 0.2 0.00033 19.7 0.0 2.7 3 1 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EIE83397.1 - 4.4e-05 23.6 0.2 0.0011 19.1 0.1 2.8 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EIE83397.1 - 0.00018 21.7 2.4 0.004 17.4 0.0 3.5 3 1 0 3 3 3 1 AAA domain AAA_17 PF13207.1 EIE83397.1 - 0.00019 22.2 0.3 0.001 19.8 0.0 2.5 3 0 0 3 3 1 1 AAA domain AAA_16 PF13191.1 EIE83397.1 - 0.00055 19.9 0.2 0.0047 16.9 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain NTPase_1 PF03266.10 EIE83397.1 - 0.00055 19.6 0.5 0.11 12.1 0.0 2.9 2 1 1 3 3 2 1 NTPase AAA_2 PF07724.9 EIE83397.1 - 0.00087 19.2 0.0 0.0031 17.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 EIE83397.1 - 0.0013 18.5 0.1 0.0045 16.8 0.0 2.0 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.17 EIE83397.1 - 0.014 15.5 0.0 0.041 14.0 0.0 1.8 1 0 0 1 1 1 0 RNA helicase SKI PF01202.17 EIE83397.1 - 0.02 14.7 0.0 0.053 13.3 0.0 1.8 1 0 0 1 1 1 0 Shikimate kinase UPF0079 PF02367.12 EIE83397.1 - 0.026 14.1 0.0 0.058 13.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_19 PF13245.1 EIE83397.1 - 0.042 13.5 0.1 0.11 12.3 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_3 PF07726.6 EIE83397.1 - 0.071 12.7 0.0 0.23 11.0 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 EIE83397.1 - 0.1 11.9 0.0 0.23 10.8 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF258 PF03193.11 EIE83397.1 - 0.11 11.6 0.0 0.28 10.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 EIE83397.1 - 0.13 11.6 0.0 0.3 10.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Bap31 PF05529.7 EIE83398.1 - 0.12 11.7 2.4 0.11 11.8 0.6 1.7 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like Seryl_tRNA_N PF02403.17 EIE83398.1 - 0.42 10.6 4.9 0.12 12.4 1.0 1.8 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DDE_3 PF13358.1 EIE83399.1 - 3.4e-11 43.0 0.4 3.8e-11 42.9 0.3 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE83401.1 - 1.3e-19 70.4 0.0 8.2e-19 67.8 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 EIE83401.1 - 2.3e-11 43.4 1.3 9.4e-11 41.4 0.3 2.5 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP PF00077.15 EIE83401.1 - 0.0057 16.5 0.2 0.025 14.5 0.0 2.2 2 0 0 2 2 2 1 Retroviral aspartyl protease DUF2361 PF10153.4 EIE83401.1 - 0.018 15.2 0.6 0.018 15.2 0.4 2.2 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2361) Asp_protease_2 PF13650.1 EIE83401.1 - 0.1 13.1 0.1 0.43 11.0 0.0 2.1 2 0 0 2 2 2 0 Aspartyl protease rve PF00665.21 EIE83402.1 - 3.5e-25 88.4 0.0 7.3e-25 87.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 EIE83402.1 - 1.3e-09 37.6 0.8 2.8e-09 36.5 0.5 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve_3 PF13683.1 EIE83402.1 - 0.0054 16.2 0.0 0.015 14.8 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE83403.1 - 2e-18 66.5 0.5 1.4e-08 34.3 0.2 2.4 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease PF09668.5 EIE83403.1 - 8.2e-10 38.3 0.0 1.6e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 EIE83403.1 - 5.3e-06 26.8 0.0 1.3e-05 25.5 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 EIE83403.1 - 4.4e-05 23.3 0.0 0.00015 21.6 0.0 2.0 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.6 EIE83403.1 - 0.00068 19.5 0.0 0.0013 18.6 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EIE83403.1 - 0.0047 16.7 0.1 0.0097 15.7 0.1 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease rve PF00665.21 EIE83404.1 - 1.8e-27 95.8 0.0 6.2e-27 94.0 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.1 EIE83404.1 - 1.9e-05 24.0 0.0 4.3e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.12 EIE83406.1 - 6.6e-05 22.9 0.9 0.00014 21.8 0.1 1.9 2 0 0 2 2 2 1 Retrotransposon gag protein HTH_Tnp_Tc3_2 PF01498.13 EIE83407.1 - 5.2e-17 61.6 0.5 5.2e-17 61.6 0.3 2.0 2 1 1 3 3 3 1 Transposase HTH_29 PF13551.1 EIE83407.1 - 2.3e-05 24.4 0.3 4.5e-05 23.5 0.2 1.5 1 1 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.1 EIE83407.1 - 0.0048 17.6 0.5 0.034 14.9 0.0 2.4 1 1 2 3 3 3 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.13 EIE83408.1 - 1.2e-07 31.7 0.2 4.5e-07 29.8 0.0 2.0 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.1 EIE83408.1 - 0.13 11.9 0.0 0.28 10.8 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain PIF1 PF05970.9 EIE83409.1 - 3.7e-16 59.0 0.2 4.5e-16 58.7 0.1 1.1 1 0 0 1 1 1 1 PIF1-like helicase UvrD_C_2 PF13538.1 EIE83409.1 - 0.029 14.4 0.0 0.039 14.0 0.0 1.3 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.9 EIE83409.1 - 0.072 10.8 0.0 0.084 10.6 0.0 1.0 1 0 0 1 1 1 0 Helicase DDE_3 PF13358.1 EIE83410.1 - 9.6e-20 70.8 0.2 1.7e-19 70.0 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE83410.1 - 3.2e-10 39.9 0.1 8.4e-10 38.5 0.1 1.8 1 0 0 1 1 1 1 Transposase rve PF00665.21 EIE83410.1 - 0.039 14.0 0.0 0.11 12.6 0.0 1.9 1 1 0 1 1 1 0 Integrase core domain HMG_box_2 PF09011.5 EIE83410.1 - 0.068 13.5 2.2 0.082 13.2 0.3 2.0 2 0 0 2 2 2 0 HMG-box domain HMG_box PF00505.14 EIE83410.1 - 0.071 13.3 1.2 0.33 11.2 0.6 2.3 2 1 0 2 2 2 0 HMG (high mobility group) box HTH_21 PF13276.1 EIE83410.1 - 0.083 12.9 0.1 1.5 8.9 0.0 2.5 2 0 0 2 2 2 0 HTH-like domain Leader_Erm PF08253.6 EIE83411.1 - 0.33 10.4 0.3 0.33 10.4 0.2 2.1 2 0 0 2 2 2 0 Erm Leader peptide Ribosom_S12_S23 PF00164.20 EIE83412.1 - 1.3e-51 173.1 2.3 1.5e-51 172.9 1.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 UreE_N PF02814.10 EIE83412.1 - 0.1 12.1 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 UreE urease accessory protein, N-terminal domain DUF2834 PF11196.3 EIE83414.1 - 0.018 15.1 0.0 0.033 14.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2834) RRM_1 PF00076.17 EIE83415.1 - 1.2e-06 28.0 0.0 2.4e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE83415.1 - 1.1e-05 25.2 0.0 2.1e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE83415.1 - 0.0056 16.4 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spo7_2_N PF15407.1 EIE83415.1 - 0.018 14.5 0.0 0.064 12.7 0.0 2.0 1 0 0 1 1 1 0 Sporulation protein family 7 Peptidase_S49_N PF08496.5 EIE83415.1 - 9.8 5.9 8.0 7.2 6.3 2.1 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Histone PF00125.19 EIE83416.1 - 1.4e-31 108.4 0.4 2.1e-31 107.8 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EIE83416.1 - 1.2e-05 25.3 0.0 1.8e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EIE83416.1 - 0.0061 16.6 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 EIE83416.1 - 0.014 14.6 1.1 0.023 13.9 0.8 1.5 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 EIE83416.1 - 0.019 14.6 0.1 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.19 EIE83417.1 - 4.4e-15 55.5 0.2 5.3e-15 55.3 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EIE83417.1 - 2.1e-05 24.5 0.1 3.5e-05 23.9 0.1 1.5 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 EIE83417.1 - 4.5e-05 23.3 0.1 6.3e-05 22.8 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 EIE83417.1 - 0.00013 21.9 0.1 0.00023 21.1 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 EIE83417.1 - 0.012 14.9 0.0 0.012 14.9 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 EIE83417.1 - 0.043 13.5 0.0 0.068 12.9 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.8 EIE83417.1 - 0.11 12.7 0.1 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Histone PF00125.19 EIE83418.1 - 1.2e-25 89.4 0.0 1.5e-25 89.0 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EIE83418.1 - 2.4e-05 24.3 0.0 3.2e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EIE83419.1 - 5e-24 84.2 0.5 7.4e-24 83.6 0.4 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EIE83419.1 - 6.3e-07 29.3 0.0 1.7e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 EIE83419.1 - 0.00017 21.7 0.0 0.0003 20.9 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF2950 PF11453.3 EIE83419.1 - 0.11 11.4 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2950) DUF1312 PF07009.6 EIE83420.1 - 0.06 13.1 0.0 0.064 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1312) Glyco_hydro_28 PF00295.12 EIE83421.1 - 2.2e-70 237.1 21.9 2.8e-70 236.8 15.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 DUF867 PF05908.6 EIE83421.1 - 0.075 12.1 0.1 0.13 11.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF867) Zn_clus PF00172.13 EIE83422.1 - 0.0045 16.8 15.2 0.0065 16.3 10.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AT_hook PF02178.14 EIE83422.1 - 0.14 11.9 2.8 0.25 11.1 2.0 1.5 1 0 0 1 1 1 0 AT hook motif FHA PF00498.21 EIE83423.1 - 0.00072 19.6 0.1 0.0024 17.9 0.1 2.0 1 0 0 1 1 1 1 FHA domain Fork_head PF00250.13 EIE83423.1 - 0.0016 18.4 0.0 0.0045 17.0 0.0 1.7 1 1 0 1 1 1 1 Fork head domain Peptidase_M10_C PF08548.6 EIE83423.1 - 0.0041 16.7 0.1 0.0061 16.1 0.1 1.2 1 0 0 1 1 1 1 Peptidase M10 serralysin C terminal Inositol_P PF00459.20 EIE83423.1 - 0.46 9.7 3.7 0.7 9.1 2.6 1.3 1 0 0 1 1 1 0 Inositol monophosphatase family His_Phos_2 PF00328.17 EIE83424.1 - 2.7e-06 26.9 0.0 3.1e-06 26.7 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) SlyX PF04102.7 EIE83424.1 - 0.02 15.2 0.1 1.7 9.0 0.0 2.3 2 0 0 2 2 2 0 SlyX RestrictionSfiI PF11487.3 EIE83424.1 - 0.026 13.7 0.0 0.032 13.3 0.0 1.1 1 0 0 1 1 1 0 Type II restriction enzyme SfiI NUC130_3NT PF08158.7 EIE83424.1 - 0.14 12.5 0.1 0.28 11.4 0.1 1.5 1 0 0 1 1 1 0 NUC130/3NT domain DUF676 PF05057.9 EIE83425.1 - 0.14 11.3 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Kinesin PF00225.18 EIE83426.1 - 3.6e-73 246.1 0.1 3.6e-73 246.1 0.1 2.3 2 0 0 2 2 2 1 Kinesin motor domain DegQ PF08181.6 EIE83426.1 - 0.023 14.4 0.6 0.023 14.4 0.4 2.6 2 0 0 2 2 2 0 DegQ (SacQ) family DUF3605 PF12239.3 EIE83427.1 - 1.7e-15 57.1 2.8 1.4e-13 50.9 1.9 2.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3605) Baculo_IE-1 PF05290.6 EIE83428.1 - 0.008 15.9 1.9 0.011 15.4 1.3 1.2 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-C3HC4 PF00097.20 EIE83428.1 - 0.013 15.1 3.1 0.022 14.4 2.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIE83428.1 - 0.015 15.1 5.5 0.031 14.1 3.8 1.5 1 0 0 1 1 1 0 Ring finger domain HAUS2 PF15003.1 EIE83428.1 - 0.056 12.5 0.4 0.066 12.2 0.3 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 2 Pou PF00157.12 EIE83428.1 - 0.11 12.1 0.1 0.4 10.3 0.0 1.8 1 1 1 2 2 2 0 Pou domain - N-terminal to homeobox domain zf-C3HC4_2 PF13923.1 EIE83428.1 - 0.13 12.2 5.2 0.24 11.4 3.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EIE83428.1 - 0.29 10.8 3.9 0.48 10.1 2.7 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) SMN PF06003.7 EIE83428.1 - 0.39 9.7 4.4 0.78 8.7 3.0 1.5 1 1 0 1 1 1 0 Survival motor neuron protein (SMN) Cwf_Cwc_15 PF04889.7 EIE83429.1 - 4 7.0 8.2 0.43 10.2 2.3 1.7 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein AMP-binding PF00501.23 EIE83430.1 - 1.3e-99 333.4 0.0 2.4e-98 329.3 0.0 2.0 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 EIE83430.1 - 2.4e-19 70.0 0.7 5.5e-19 68.8 0.1 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF3712 PF12505.3 EIE83431.1 - 3.9e-71 236.8 33.7 1.6e-25 89.5 1.6 6.9 7 0 0 7 7 7 4 Protein of unknown function (DUF3712) LEA_2 PF03168.8 EIE83431.1 - 8.6e-08 32.4 19.3 0.037 14.4 0.1 7.4 9 0 0 9 9 9 4 Late embryogenesis abundant protein Sigma_reg_N PF13800.1 EIE83431.1 - 0.014 15.4 1.1 0.044 13.8 0.8 1.9 1 0 0 1 1 1 0 Sigma factor regulator N-terminal YukC PF10140.4 EIE83431.1 - 0.19 10.2 0.2 0.33 9.4 0.1 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Tmemb_9 PF05434.6 EIE83431.1 - 1.1 8.9 1.1 2.2 8.0 0.8 1.4 1 0 0 1 1 1 0 TMEM9 UPF0220 PF05255.6 EIE83432.1 - 9.1e-41 138.8 4.0 1.1e-40 138.6 2.7 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) RasGAP PF00616.14 EIE83433.1 - 3.9e-53 180.0 0.1 3.9e-53 180.0 0.0 2.6 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 EIE83433.1 - 2.6e-29 101.7 5.7 2.6e-29 101.7 3.9 2.3 3 0 0 3 3 3 1 RasGAP C-terminus DUF972 PF06156.8 EIE83433.1 - 4.1 7.8 7.4 3.6 7.9 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF972) Pkinase PF00069.20 EIE83436.1 - 7.1e-59 199.0 0.0 8.7e-59 198.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE83436.1 - 1.7e-31 109.2 0.0 2e-31 109.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIE83436.1 - 0.00046 20.0 0.0 0.00067 19.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EIE83436.1 - 0.002 17.0 0.0 0.0029 16.4 0.0 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Kdo PF06293.9 EIE83436.1 - 0.033 13.2 0.0 0.14 11.1 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Apc4_WD40 PF12894.2 EIE83436.1 - 0.064 12.7 0.0 0.17 11.4 0.0 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Kinase-like PF14531.1 EIE83436.1 - 0.11 11.4 0.0 0.18 10.7 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Pkinase PF00069.20 EIE83440.1 - 1.1e-60 205.0 0.0 6.6e-60 202.4 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE83440.1 - 1.5e-34 119.2 0.0 2.2e-34 118.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE83440.1 - 2.8e-05 23.2 0.1 7e-05 21.9 0.1 1.5 1 1 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EIE83440.1 - 0.024 13.5 0.0 0.041 12.7 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.9 EIE83440.1 - 0.055 12.5 0.0 0.097 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIE83440.1 - 0.12 12.1 0.0 0.26 10.9 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Sugar_tr PF00083.19 EIE83441.1 - 1.2e-100 337.3 23.2 7.3e-51 173.1 5.6 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EIE83441.1 - 4.6e-27 94.6 49.4 4.4e-24 84.8 12.0 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4341 PF14241.1 EIE83441.1 - 0.5 10.1 13.8 0.1 12.3 5.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4341) Ribosomal_L5_C PF00673.16 EIE83442.1 - 2.2e-22 78.5 0.0 3.2e-22 78.0 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 EIE83442.1 - 1.7e-19 69.3 0.1 5.2e-19 67.7 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L5 LSM PF01423.17 EIE83443.1 - 3e-17 61.9 0.3 4.4e-17 61.3 0.2 1.2 1 0 0 1 1 1 1 LSM domain TBCA PF02970.11 EIE83445.1 - 6.8e-30 102.9 10.3 8.2e-30 102.7 7.1 1.1 1 0 0 1 1 1 1 Tubulin binding cofactor A Spc7 PF08317.6 EIE83445.1 - 0.0031 16.2 4.2 0.0031 16.2 2.9 1.6 1 1 0 1 1 1 1 Spc7 kinetochore protein OmdA PF13376.1 EIE83445.1 - 0.0077 15.8 1.2 0.075 12.7 0.1 2.2 2 0 0 2 2 2 1 Bacteriocin-protection, YdeI or OmpD-Associated Mnd1 PF03962.10 EIE83445.1 - 0.0097 15.5 8.3 0.01 15.4 5.8 1.0 1 0 0 1 1 1 1 Mnd1 family YfbU PF03887.9 EIE83445.1 - 0.014 14.9 0.1 0.025 14.1 0.1 1.3 1 0 0 1 1 1 0 YfbU domain PMEI PF04043.10 EIE83445.1 - 0.071 13.0 0.5 0.086 12.7 0.3 1.1 1 0 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor FliE PF02049.13 EIE83445.1 - 0.12 12.4 3.2 0.13 12.3 1.0 1.8 1 1 1 2 2 2 0 Flagellar hook-basal body complex protein FliE Prok-TraM PF09228.5 EIE83445.1 - 0.14 12.2 0.8 0.14 12.2 0.5 2.1 2 1 0 2 2 2 0 Prokaryotic Transcriptional repressor TraM DUF4239 PF14023.1 EIE83445.1 - 0.24 10.7 1.6 0.33 10.3 1.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4239) Peptidase_C6 PF00851.13 EIE83445.1 - 0.24 9.9 4.4 0.29 9.7 3.1 1.0 1 0 0 1 1 1 0 Helper component proteinase DUF4164 PF13747.1 EIE83445.1 - 0.54 10.4 6.4 0.32 11.1 0.6 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) DUF342 PF03961.8 EIE83445.1 - 0.87 7.9 6.7 1 7.7 4.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF1311 PF07007.7 EIE83445.1 - 1.2 9.2 6.0 0.52 10.4 1.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1311) HSCB_C PF07743.8 EIE83445.1 - 1.3 9.5 6.2 1.1 9.7 0.7 2.2 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain Val_tRNA-synt_C PF10458.4 EIE83445.1 - 1.4 9.0 7.5 8.9 6.4 0.3 3.0 2 1 1 3 3 3 0 Valyl tRNA synthetase tRNA binding arm Syntaxin PF00804.20 EIE83445.1 - 1.7 8.8 9.1 7.3 6.8 6.3 1.8 1 1 0 1 1 1 0 Syntaxin GreA_GreB_N PF03449.10 EIE83445.1 - 2.5 8.2 7.5 0.41 10.7 1.0 2.2 1 1 0 2 2 2 0 Transcription elongation factor, N-terminal APG6 PF04111.7 EIE83445.1 - 4.5 6.2 7.9 5.4 5.9 5.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 TMPIT PF07851.8 EIE83445.1 - 5 6.0 6.1 6.2 5.7 4.2 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF2458 PF10454.4 EIE83445.1 - 5.4 6.8 9.3 13 5.6 6.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2458) Spectrin PF00435.16 EIE83445.1 - 5.8 7.2 9.5 11 6.3 4.6 2.1 1 1 1 2 2 2 0 Spectrin repeat Spc24 PF08286.6 EIE83445.1 - 6.8 6.4 8.4 2 8.1 2.0 2.0 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 IncA PF04156.9 EIE83445.1 - 8.2 5.9 7.7 9.8 5.7 5.3 1.2 1 0 0 1 1 1 0 IncA protein CIA30 PF08547.7 EIE83446.1 - 3.6e-43 147.1 0.0 4.2e-43 146.9 0.0 1.0 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) CBM_11 PF03425.8 EIE83446.1 - 0.033 13.8 0.2 0.046 13.4 0.1 1.4 1 1 0 1 1 1 0 Carbohydrate binding domain (family 11) HbrB PF08539.6 EIE83447.1 - 9.2e-20 71.0 2.9 2.2e-10 40.6 0.9 2.8 2 1 1 3 3 3 2 HbrB-like ESAG1 PF03238.8 EIE83447.1 - 0.079 12.2 0.1 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 ESAG protein Glyco_hydro_18 PF00704.23 EIE83448.1 - 4.1e-16 59.3 1.4 5.5e-15 55.6 0.0 2.2 1 1 0 2 2 2 1 Glycosyl hydrolases family 18 CBM_5_12 PF02839.9 EIE83448.1 - 6.2e-08 32.0 23.1 3.3e-07 29.7 7.1 3.2 3 0 0 3 3 3 2 Carbohydrate binding domain MIF4G PF02854.14 EIE83449.1 - 2.4e-28 99.0 5.4 8e-28 97.2 3.7 2.0 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.12 EIE83449.1 - 1.1e-22 79.8 0.1 4.7e-22 77.8 0.1 2.2 1 0 0 1 1 1 1 MA3 domain Homeobox PF00046.24 EIE83450.1 - 4.9e-06 26.0 0.0 1.3e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EIE83450.1 - 1.3e-05 24.8 0.1 3.5e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 Homeobox KN domain SPOUT_MTase PF02590.12 EIE83451.1 - 0.12 12.0 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 Predicted SPOUT methyltransferase Methyltransf_23 PF13489.1 EIE83452.1 - 9e-15 54.7 0.0 1.5e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIE83452.1 - 3.9e-14 52.9 0.0 1.2e-13 51.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIE83452.1 - 9.8e-12 45.2 0.0 3e-11 43.6 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIE83452.1 - 9.7e-11 41.4 0.1 3.4e-10 39.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIE83452.1 - 3.6e-09 37.1 0.0 7.2e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIE83452.1 - 4e-09 36.7 0.0 9.7e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 EIE83452.1 - 2.5e-07 29.9 0.0 0.0031 16.5 0.0 2.5 1 1 1 2 2 2 2 NNMT/PNMT/TEMT family MTS PF05175.9 EIE83452.1 - 3.6e-05 23.2 0.0 7.6e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EIE83452.1 - 5.3e-05 23.2 0.0 0.00011 22.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DUF3419 PF11899.3 EIE83452.1 - 5.7e-05 22.0 0.0 9.1e-05 21.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Ubie_methyltran PF01209.13 EIE83452.1 - 0.00011 21.4 0.0 0.00019 20.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family TPMT PF05724.6 EIE83452.1 - 0.00032 20.1 0.0 0.00069 19.1 0.0 1.5 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) TehB PF03848.9 EIE83452.1 - 0.00035 19.7 0.0 0.00077 18.6 0.0 1.6 2 0 0 2 2 2 1 Tellurite resistance protein TehB CheR PF01739.13 EIE83452.1 - 0.0017 17.7 0.0 0.15 11.3 0.0 2.6 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain Methyltransf_24 PF13578.1 EIE83452.1 - 0.0023 18.7 0.0 0.007 17.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain NodS PF05401.6 EIE83452.1 - 0.0032 16.8 0.0 0.0061 15.9 0.0 1.4 1 0 0 1 1 1 1 Nodulation protein S (NodS) DUF1363 PF07101.6 EIE83452.1 - 0.0044 17.0 0.0 0.0075 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1363) CMAS PF02353.15 EIE83452.1 - 0.016 14.2 0.0 0.036 13.1 0.0 1.5 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_8 PF05148.10 EIE83452.1 - 0.023 14.3 0.0 0.06 12.9 0.0 1.8 2 0 0 2 2 2 0 Hypothetical methyltransferase Ribosomal_S4 PF00163.14 EIE83453.1 - 4.2e-28 97.5 1.0 7.6e-28 96.7 0.7 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 EIE83453.1 - 3.1e-13 48.9 1.4 3.1e-13 48.9 1.0 2.4 3 0 0 3 3 3 1 S4 domain Ribosomal_L21e PF01157.13 EIE83454.1 - 4.8e-43 144.9 4.7 6.7e-43 144.5 3.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L21e DUF1989 PF09347.5 EIE83454.1 - 0.0038 16.6 0.0 0.0051 16.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) Surface_Ag_2 PF01617.12 EIE83454.1 - 0.064 12.4 0.2 0.074 12.2 0.1 1.2 1 0 0 1 1 1 0 Surface antigen LRS4 PF10422.4 EIE83454.1 - 0.086 12.1 0.0 0.1 11.9 0.0 1.1 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 MIF4G PF02854.14 EIE83455.1 - 1.2e-29 103.2 0.2 4.3e-29 101.4 0.0 1.9 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.12 EIE83455.1 - 1.8e-22 79.1 0.0 4.2e-22 77.9 0.0 1.6 1 0 0 1 1 1 1 MA3 domain Catalase PF00199.14 EIE83456.1 - 0.017 13.8 0.0 0.019 13.6 0.0 1.0 1 0 0 1 1 1 0 Catalase DUF605 PF04652.11 EIE83457.1 - 4.2 6.6 7.1 4.3 6.6 4.9 1.2 1 0 0 1 1 1 0 Vta1 like FGGY_N PF00370.16 EIE83458.1 - 8.5e-48 162.8 0.5 7e-45 153.2 0.1 2.2 1 1 1 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 EIE83458.1 - 6.3e-38 130.3 0.5 4.5e-19 68.8 0.1 2.3 1 1 1 2 2 2 2 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.15 EIE83458.1 - 0.055 12.7 0.0 0.11 11.8 0.0 1.5 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family DUF1295 PF06966.7 EIE83459.1 - 1.4e-38 132.5 6.9 1.8e-38 132.1 4.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.9 EIE83459.1 - 0.011 15.9 0.6 0.046 13.9 0.0 2.4 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF3894 PF13033.1 EIE83459.1 - 0.27 11.2 5.4 4.9 7.2 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3894) Ribosomal_L1 PF00687.16 EIE83460.1 - 1.5e-41 142.1 10.5 1.5e-41 142.1 7.3 2.0 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family Phosphodiest PF01663.17 EIE83461.1 - 1.4e-10 41.0 1.0 5.5e-09 35.8 0.0 2.3 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 EIE83461.1 - 0.00078 18.9 0.0 0.0092 15.3 0.0 2.1 1 1 1 2 2 2 2 Metalloenzyme superfamily Chitin_synth_1 PF01644.12 EIE83461.1 - 0.069 12.9 0.1 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 Chitin synthase GTP_EFTU_D3 PF03143.12 EIE83462.1 - 0.066 13.3 0.2 0.074 13.2 0.1 1.0 1 0 0 1 1 1 0 Elongation factor Tu C-terminal domain zf-H2C2_2 PF13465.1 EIE83463.1 - 4.4e-08 33.0 15.0 1.3e-05 25.2 3.3 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 EIE83463.1 - 8.9e-07 28.9 17.2 0.0024 18.1 1.1 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIE83463.1 - 2.7e-05 24.1 13.9 0.014 15.6 1.6 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 EIE83463.1 - 0.8 9.9 6.4 8.2 6.7 1.3 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.1 EIE83463.1 - 1.1 9.0 16.4 0.13 11.9 0.6 2.7 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.2 EIE83463.1 - 8.8 6.5 14.0 1.5 9.0 1.7 2.9 2 2 1 3 3 3 0 C2H2 type zinc-finger (2 copies) Homeobox PF00046.24 EIE83465.1 - 2.7e-16 58.9 3.9 6.3e-16 57.7 2.7 1.6 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EIE83465.1 - 9.1e-05 22.0 0.2 0.00029 20.4 0.1 1.9 1 0 0 1 1 1 1 Homeobox KN domain GHBP PF12772.2 EIE83465.1 - 0.027 13.8 5.5 0.032 13.6 3.8 1.1 1 0 0 1 1 1 0 Growth hormone receptor binding Homez PF11569.3 EIE83465.1 - 0.091 11.8 1.1 0.23 10.5 0.1 2.1 2 1 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez Strabismus PF06638.6 EIE83465.1 - 0.13 10.5 3.3 0.16 10.2 2.3 1.1 1 0 0 1 1 1 0 Strabismus protein SPATIAL PF15256.1 EIE83465.1 - 0.53 10.3 10.6 0.6 10.1 7.3 1.0 1 0 0 1 1 1 0 SPATIAL Senescence_reg PF04520.8 EIE83465.1 - 1.1 9.7 7.5 1.3 9.5 4.7 1.3 1 1 0 1 1 1 0 Senescence regulator MDFI PF15316.1 EIE83465.1 - 1.5 8.7 7.0 1.9 8.4 4.9 1.1 1 0 0 1 1 1 0 MyoD family inhibitor RP-C_C PF11800.3 EIE83465.1 - 2.2 7.9 6.9 2.4 7.8 4.8 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region Neur_chan_memb PF02932.11 EIE83465.1 - 7.7 6.3 8.5 9.4 6.0 5.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ank PF00023.25 EIE83467.1 - 9e-10 37.8 3.1 6.5e-06 25.6 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.2 EIE83467.1 - 1.1e-09 38.4 0.5 2.8e-09 37.1 0.4 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EIE83467.1 - 2.4e-08 33.4 0.9 0.00011 22.1 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.1 EIE83467.1 - 2.1e-07 31.2 0.4 0.0063 16.9 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EIE83467.1 - 4.1e-06 26.8 1.2 0.22 11.8 0.1 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Flt3_lig PF02947.9 EIE83467.1 - 0.11 12.4 1.0 0.87 9.4 0.0 2.4 3 0 0 3 3 3 0 flt3 ligand Kinesin PF00225.18 EIE83468.1 - 3.2e-89 298.9 0.1 5.6e-89 298.1 0.1 1.4 1 0 0 1 1 1 1 Kinesin motor domain E1_DerP2_DerF2 PF02221.10 EIE83469.1 - 5e-13 49.4 0.0 5.8e-13 49.2 0.0 1.0 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 EIE83469.1 - 0.00021 21.3 0.0 0.0016 18.5 0.0 1.9 1 1 0 1 1 1 1 ML-like domain Flg_bbr_C PF06429.8 EIE83469.1 - 0.052 13.4 0.0 0.073 12.9 0.0 1.2 1 0 0 1 1 1 0 Flagellar basal body rod FlgEFG protein C-terminal Mito_carr PF00153.22 EIE83470.1 - 8.5e-41 137.5 8.4 1.3e-17 63.2 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein ArsB PF02040.10 EIE83470.1 - 0.049 12.5 0.4 0.092 11.6 0.0 1.5 2 0 0 2 2 2 0 Arsenical pump membrane protein PDT PF00800.13 EIE83471.1 - 7.3e-65 217.9 0.2 9.9e-65 217.4 0.1 1.2 1 0 0 1 1 1 1 Prephenate dehydratase CM_2 PF01817.16 EIE83471.1 - 2.7e-21 75.4 0.2 6.8e-21 74.1 0.2 1.7 1 0 0 1 1 1 1 Chorismate mutase type II ACT PF01842.20 EIE83471.1 - 1.2e-05 24.6 0.0 3.7e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 ACT domain DUF2373 PF10180.4 EIE83472.1 - 1.1e-18 66.4 3.2 2.7e-18 65.2 2.2 1.7 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) P16-Arc PF04699.9 EIE83472.1 - 0.0028 17.6 2.5 0.0028 17.6 1.7 2.8 2 1 1 3 3 3 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Vps39_1 PF10366.4 EIE83472.1 - 2 8.4 6.5 0.34 10.9 0.5 2.6 2 1 2 4 4 4 0 Vacuolar sorting protein 39 domain 1 PTPlike_phytase PF14566.1 EIE83472.1 - 2.1 8.3 12.9 14 5.7 8.7 2.6 1 1 0 1 1 1 0 Inositol hexakisphosphate G-gamma PF00631.17 EIE83473.1 - 0.15 11.8 0.5 0.38 10.5 0.1 1.9 2 0 0 2 2 2 0 GGL domain RVT_1 PF00078.22 EIE83476.1 - 1.8e-25 89.6 0.0 4.6e-25 88.2 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1499 PF07386.6 EIE83477.1 - 0.023 14.8 0.4 0.026 14.6 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1499) Tim17 PF02466.14 EIE83478.1 - 2.4e-35 121.3 6.0 2.9e-35 121.1 4.1 1.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF4235 PF14019.1 EIE83478.1 - 0.17 11.7 2.5 1.4 8.7 1.7 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4235) Bromodomain PF00439.20 EIE83479.1 - 2.3e-18 65.9 1.0 6.7e-18 64.3 0.7 1.8 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.8 EIE83479.1 - 4.5e-09 35.8 0.0 1.9e-08 33.9 0.0 2.0 2 0 0 2 2 2 1 Bromodomain associated Glyco_hydro_31 PF01055.21 EIE83480.1 - 1.4e-48 165.8 0.8 1.7e-48 165.5 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 RNA_pol_Rpb1_5 PF04998.12 EIE83482.1 - 4.8e-96 321.2 0.0 3.1e-95 318.6 0.0 2.1 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EIE83482.1 - 2e-61 206.7 0.1 5.1e-61 205.4 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EIE83482.1 - 2.3e-35 121.6 0.0 6e-35 120.3 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 EIE83482.1 - 3.9e-24 84.4 0.1 1.4e-23 82.6 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_1 PF04997.7 EIE83482.1 - 3.3e-23 82.4 7.2 3.5e-23 82.4 0.4 3.5 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 1 Voltage_CLC PF00654.15 EIE83483.1 - 4.5e-82 275.9 16.9 6.4e-82 275.4 11.7 1.2 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.23 EIE83483.1 - 1.4e-08 34.3 1.0 1.1e-06 28.2 0.1 2.5 2 0 0 2 2 2 2 CBS domain XPA_C PF05181.7 EIE83484.1 - 1e-14 53.8 0.3 2.1e-14 52.8 0.2 1.5 1 0 0 1 1 1 1 XPA protein C-terminus S10_plectin PF03501.10 EIE83485.1 - 1.7e-42 143.2 0.1 2e-42 142.9 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain DUF2250 PF10007.4 EIE83485.1 - 0.03 14.2 1.1 5.1 7.0 0.0 2.3 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) TrmB PF01978.14 EIE83485.1 - 0.033 13.8 0.0 0.08 12.6 0.0 1.6 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_45 PF14947.1 EIE83485.1 - 0.061 13.1 0.1 0.092 12.5 0.1 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix Pkinase PF00069.20 EIE83486.1 - 1.6e-49 168.3 0.0 1.9e-49 168.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE83486.1 - 1.3e-21 76.8 0.0 1.5e-21 76.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIE83486.1 - 0.0087 15.8 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EIE83486.1 - 0.032 13.5 0.0 0.042 13.1 0.0 1.1 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Ribosomal_L10 PF00466.15 EIE83487.1 - 2.7e-19 68.9 0.0 3.8e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 PY_rept_46 PF09689.5 EIE83487.1 - 0.018 15.3 0.2 0.036 14.3 0.1 1.5 1 0 0 1 1 1 0 Plasmodium yoelii repeat (PY_rept_46) Myb_DNA-binding PF00249.26 EIE83488.1 - 6e-05 23.0 0.0 8.6e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain mRNA_cap_enzyme PF01331.14 EIE83489.1 - 1.5e-14 54.1 5.3 1.2e-08 34.8 0.2 3.0 2 1 1 3 3 3 2 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 EIE83489.1 - 2.8e-12 46.8 0.3 5.6e-11 42.7 0.0 3.0 2 0 0 2 2 2 1 mRNA capping enzyme, C-terminal domain Myb_DNA-binding PF00249.26 EIE83490.1 - 0.0018 18.2 0.1 0.0054 16.7 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EIE83490.1 - 0.034 14.2 0.1 0.077 13.1 0.1 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain PPR_2 PF13041.1 EIE83491.1 - 7.3e-21 73.8 4.3 1.4e-11 44.1 0.0 4.3 4 1 0 4 4 4 3 PPR repeat family PPR_3 PF13812.1 EIE83491.1 - 6.8e-15 54.0 1.9 0.00084 19.4 0.0 6.4 7 0 0 7 7 7 3 Pentatricopeptide repeat domain PPR_1 PF12854.2 EIE83491.1 - 3.6e-12 45.5 0.0 8.2e-05 22.0 0.0 3.7 4 0 0 4 4 4 2 PPR repeat PPR PF01535.15 EIE83491.1 - 6.8e-10 38.2 12.5 5.7e-05 22.8 0.0 5.4 7 0 0 7 7 7 3 PPR repeat ATP13 PF12921.2 EIE83491.1 - 5.7e-06 25.6 0.3 0.26 10.6 0.0 3.3 3 0 0 3 3 3 2 Mitochondrial ATPase expression SbmA_BacA PF05992.7 EIE83491.1 - 0.041 13.0 0.2 0.12 11.5 0.1 1.7 2 0 0 2 2 2 0 SbmA/BacA-like family TPR_19 PF14559.1 EIE83491.1 - 0.1 12.9 0.1 11 6.3 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat DEAD PF00270.24 EIE83492.1 - 8.5e-42 142.5 0.1 8.5e-42 142.5 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EIE83492.1 - 1.2e-20 72.8 0.0 3e-20 71.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EIE83492.1 - 2.2e-17 62.6 0.0 7.1e-17 61.0 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIE83492.1 - 2.5e-07 30.7 0.0 2.5e-07 30.7 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EIE83492.1 - 0.00077 19.6 0.0 0.0025 17.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain CMS1 PF14617.1 EIE83492.1 - 0.0042 16.1 0.0 0.0042 16.1 0.0 3.1 2 1 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit AAA_19 PF13245.1 EIE83492.1 - 0.15 11.8 0.0 0.47 10.2 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain LicD PF04991.8 EIE83492.1 - 2.5 8.1 10.3 5.7 6.9 7.1 1.5 1 0 0 1 1 1 0 LicD family GAGA_bind PF06217.7 EIE83492.1 - 4.8 7.0 14.0 7.9 6.3 9.7 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Peptidase_C1_2 PF03051.10 EIE83493.1 - 3.3e-167 556.4 0.3 3.9e-167 556.2 0.2 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.18 EIE83493.1 - 0.002 18.0 0.2 1.5 8.6 0.1 2.5 2 0 0 2 2 2 2 Papain family cysteine protease CCDC92 PF14916.1 EIE83494.1 - 0.00011 21.6 0.0 0.00024 20.6 0.0 1.5 1 0 0 1 1 1 1 Coiled-coil domain of unknown function KIAA1430 PF13879.1 EIE83494.1 - 0.045 14.1 0.5 6.9 7.1 0.1 2.3 2 0 0 2 2 2 0 KIAA1430 homologue Herpes_BLRF2 PF05812.7 EIE83494.1 - 0.16 11.7 1.7 0.3 10.8 0.1 2.1 2 1 1 3 3 3 0 Herpesvirus BLRF2 protein NAD_binding_1 PF00175.16 EIE83495.1 - 3.3e-29 101.6 0.0 4.9e-29 101.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EIE83495.1 - 4.1e-22 78.1 0.0 9e-22 77.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EIE83495.1 - 3.3e-06 27.0 0.0 4.1e-05 23.5 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EIE83495.1 - 0.0033 17.3 0.0 0.0089 15.9 0.0 1.9 2 0 0 2 2 2 1 Siderophore-interacting FAD-binding domain Ank PF00023.25 EIE83496.1 - 1.4e-82 267.6 11.4 2e-10 39.9 0.0 10.3 10 0 0 10 10 10 10 Ankyrin repeat Ank_2 PF12796.2 EIE83496.1 - 2.1e-81 268.3 10.9 1.2e-21 76.8 1.8 6.0 2 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EIE83496.1 - 1e-64 207.9 6.3 8e-08 31.7 0.1 10.4 10 0 0 10 10 10 9 Ankyrin repeat Ank_5 PF13857.1 EIE83496.1 - 5.4e-62 204.4 12.3 1.5e-12 47.2 0.0 7.9 3 3 5 8 8 8 8 Ankyrin repeats (many copies) Ank_4 PF13637.1 EIE83496.1 - 5.5e-61 201.9 6.3 1.5e-10 41.2 0.0 8.5 4 3 4 9 9 9 7 Ankyrin repeats (many copies) RNA_pol_Rpb6 PF01192.17 EIE83496.1 - 0.052 13.3 0.1 0.18 11.5 0.1 2.0 1 0 0 1 1 1 0 RNA polymerase Rpb6 MCPVI PF02993.9 EIE83497.1 - 0.062 13.4 3.0 0.096 12.8 2.1 1.2 1 0 0 1 1 1 0 Minor capsid protein VI HATPase_c PF02518.21 EIE83498.1 - 2.2e-29 101.3 0.2 4.6e-29 100.3 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EIE83498.1 - 5.6e-18 64.7 0.0 2e-17 62.9 0.0 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain AAA_16 PF13191.1 EIE83498.1 - 2e-17 63.7 0.0 5.4e-17 62.3 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain GAF_2 PF13185.1 EIE83498.1 - 6.4e-12 46.1 0.0 1.8e-11 44.7 0.0 1.8 1 0 0 1 1 1 1 GAF domain Pkinase PF00069.20 EIE83498.1 - 2.2e-10 40.1 0.0 4.7e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain GAF_3 PF13492.1 EIE83498.1 - 2.6e-09 37.2 0.0 5.7e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 GAF domain GAF PF01590.21 EIE83498.1 - 5.1e-08 33.1 0.0 1.1e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 GAF domain Pkinase_Tyr PF07714.12 EIE83498.1 - 2.1e-05 23.7 0.0 3.9e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase NB-ARC PF00931.17 EIE83498.1 - 8.1e-05 21.6 0.0 0.00016 20.6 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain Response_reg PF00072.19 EIE83498.1 - 0.00032 20.6 0.0 0.001 19.0 0.0 2.0 1 0 0 1 1 1 1 Response regulator receiver domain AAA_22 PF13401.1 EIE83498.1 - 0.0045 17.1 0.0 0.026 14.6 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 EIE83498.1 - 0.012 15.8 0.0 0.055 13.6 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 EIE83498.1 - 0.064 13.5 0.0 0.23 11.7 0.0 2.0 1 0 0 1 1 1 0 ABC transporter MFS_1 PF07690.11 EIE83499.1 - 2.5e-32 111.9 22.7 2.5e-32 111.9 15.7 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1516 PF07457.6 EIE83499.1 - 0.11 12.6 0.3 0.11 12.6 0.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1516) RGS PF00615.14 EIE83500.1 - 4.7e-10 39.5 0.1 7.3e-10 38.9 0.1 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain Pkinase PF00069.20 EIE83501.1 - 1.7e-68 230.5 0.0 2.5e-68 230.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE83501.1 - 1.4e-36 125.8 0.0 2.1e-36 125.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE83501.1 - 3.7e-06 26.1 0.0 7e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EIE83501.1 - 0.0043 16.1 0.1 0.033 13.2 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIE83501.1 - 0.0096 15.6 0.0 0.025 14.3 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF2252 PF10009.4 EIE83501.1 - 0.049 12.5 1.2 0.071 12.0 0.8 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) Sororin PF09666.5 EIE83501.1 - 0.25 11.5 4.0 0.18 12.0 1.4 1.6 2 0 0 2 2 2 0 Sororin protein An_peroxidase PF03098.10 EIE83503.1 - 1.9e-54 184.9 0.0 3.1e-54 184.2 0.0 1.2 1 0 0 1 1 1 1 Animal haem peroxidase Arrestin_N PF00339.24 EIE83504.1 - 2.1e-05 24.3 0.2 0.0071 16.1 0.0 3.0 2 2 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EIE83504.1 - 2.4e-05 24.4 0.9 2.4e-05 24.4 0.6 1.7 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain DDE_3 PF13358.1 EIE83505.1 - 6.2e-11 42.2 0.0 6.5e-11 42.1 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease Arrestin_C PF02752.17 EIE83506.1 - 1.2e-09 38.4 0.0 4.7e-09 36.4 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EIE83506.1 - 0.00031 20.5 0.0 0.14 11.9 0.0 2.9 2 1 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Rgp1 PF08737.5 EIE83506.1 - 0.065 12.2 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Rgp1 TMEM164 PF14808.1 EIE83507.1 - 1.7e-23 83.1 3.6 2.3e-23 82.7 2.5 1.1 1 0 0 1 1 1 1 TMEM164 family Intg_mem_TP0381 PF09529.5 EIE83507.1 - 4.2e-10 39.2 12.8 5.9e-10 38.7 8.8 1.1 1 0 0 1 1 1 1 Integral membrane protein (intg_mem_TP0381) DUF3745 PF12560.3 EIE83507.1 - 0.029 14.0 0.3 0.051 13.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3745) Histone PF00125.19 EIE83508.1 - 4e-24 84.5 0.3 6.1e-24 83.9 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EIE83508.1 - 8.2e-07 28.9 3.1 1.5e-06 28.1 0.0 2.2 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 EIE83508.1 - 0.00016 21.9 0.0 0.00027 21.1 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.8 EIE83508.1 - 0.053 12.9 0.2 0.11 11.9 0.1 1.5 1 1 0 1 1 1 0 Replication protein C N-terminal domain Histone PF00125.19 EIE83509.1 - 1.2e-25 89.4 0.0 1.5e-25 89.0 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EIE83509.1 - 2.4e-05 24.3 0.0 3.2e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF1499 PF07386.6 EIE83510.1 - 0.032 14.4 0.5 0.038 14.1 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1499) HTH_23 PF13384.1 EIE83512.1 - 0.00034 20.1 0.0 0.00052 19.5 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain DUF1804 PF08822.6 EIE83512.1 - 0.0027 17.4 0.1 0.004 16.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1804) HTH_28 PF13518.1 EIE83512.1 - 0.0033 17.3 0.0 0.008 16.1 0.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain MerR_1 PF13411.1 EIE83512.1 - 0.16 11.7 0.5 3.1 7.6 0.0 2.2 2 0 0 2 2 2 0 MerR HTH family regulatory protein Histone PF00125.19 EIE83513.1 - 1.4e-31 108.4 0.4 2.1e-31 107.8 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EIE83513.1 - 1.2e-05 25.3 0.0 1.8e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EIE83513.1 - 0.0061 16.6 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 EIE83513.1 - 0.014 14.6 1.1 0.023 13.9 0.8 1.5 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 EIE83513.1 - 0.019 14.6 0.1 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.19 EIE83514.1 - 4.4e-15 55.5 0.2 5.3e-15 55.3 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EIE83514.1 - 2.1e-05 24.5 0.1 3.5e-05 23.9 0.1 1.5 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 EIE83514.1 - 4.5e-05 23.3 0.1 6.3e-05 22.8 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 EIE83514.1 - 0.00013 21.9 0.1 0.00023 21.1 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 EIE83514.1 - 0.012 14.9 0.0 0.012 14.9 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 EIE83514.1 - 0.043 13.5 0.0 0.068 12.9 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.8 EIE83514.1 - 0.11 12.7 0.1 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Histone PF00125.19 EIE83517.1 - 1.2e-25 89.4 0.0 1.5e-25 89.0 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EIE83517.1 - 2.4e-05 24.3 0.0 3.2e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EIE83518.1 - 4e-24 84.5 0.3 6.1e-24 83.9 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EIE83518.1 - 8.2e-07 28.9 3.1 1.5e-06 28.1 0.0 2.2 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 EIE83518.1 - 0.00016 21.9 0.0 0.00027 21.1 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.8 EIE83518.1 - 0.053 12.9 0.2 0.11 11.9 0.1 1.5 1 1 0 1 1 1 0 Replication protein C N-terminal domain Ribosomal_L18e PF00828.14 EIE83519.1 - 3.2e-24 85.7 0.1 3.5e-24 85.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 adh_short PF00106.20 EIE83520.1 - 6.3e-29 101.0 0.1 8.3e-29 100.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIE83520.1 - 1.2e-21 77.5 0.0 1.6e-21 77.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIE83520.1 - 4.2e-08 33.0 0.1 6.5e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 EIE83520.1 - 0.014 14.5 0.0 0.02 14.0 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 EIE83520.1 - 0.015 14.7 0.0 0.024 14.0 0.0 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family YfzA PF14118.1 EIE83521.1 - 3.9 7.6 11.4 0.11 12.6 0.6 3.2 2 2 0 2 2 2 0 YfzA-like protein PHD PF00628.24 EIE83522.1 - 4.3e-09 35.9 18.5 4.4e-09 35.8 11.8 1.9 2 0 0 2 2 2 1 PHD-finger DUF605 PF04652.11 EIE83522.1 - 0.0023 17.3 11.4 0.0023 17.3 7.9 2.0 1 1 0 2 2 2 1 Vta1 like PHD_2 PF13831.1 EIE83522.1 - 0.042 13.1 9.7 0.097 12.0 6.7 1.7 1 0 0 1 1 1 0 PHD-finger DUF3887 PF13026.1 EIE83523.1 - 0.022 15.0 0.7 0.032 14.4 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3887) BBS2_C PF14782.1 EIE83523.1 - 0.035 12.6 0.1 0.036 12.6 0.1 1.1 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal AAA_14 PF13173.1 EIE83523.1 - 0.049 13.5 0.4 0.069 13.0 0.2 1.3 1 1 0 1 1 1 0 AAA domain Cytochrome_C7 PF14522.1 EIE83523.1 - 0.078 12.6 0.3 0.12 12.0 0.2 1.3 1 0 0 1 1 1 0 Cytochrome c7 AF0941-like PF14591.1 EIE83523.1 - 0.14 12.2 1.2 0.23 11.5 0.8 1.5 1 1 0 1 1 1 0 AF0941-like CobA_CobO_BtuR PF02572.10 EIE83523.1 - 0.16 11.5 0.7 0.25 10.9 0.3 1.4 1 1 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP TFIIS_C PF01096.13 EIE83524.1 - 3.3e-14 52.2 0.8 3.8e-14 52.0 0.5 1.1 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Lar_restr_allev PF14354.1 EIE83524.1 - 0.005 17.1 0.4 0.0053 17.0 0.3 1.1 1 0 0 1 1 1 1 Restriction alleviation protein Lar Zn_Tnp_IS1595 PF12760.2 EIE83524.1 - 0.02 14.6 2.7 0.034 13.9 1.9 1.4 1 1 0 1 1 1 0 Transposase zinc-ribbon domain Ogr_Delta PF04606.7 EIE83524.1 - 0.025 14.2 2.2 0.051 13.2 1.5 1.5 1 1 0 1 1 1 0 Ogr/Delta-like zinc finger zinc_ribbon_5 PF13719.1 EIE83524.1 - 0.053 13.1 0.6 1 8.9 0.0 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS1 PF03811.8 EIE83524.1 - 0.064 12.7 0.2 0.11 12.0 0.2 1.4 1 0 0 1 1 1 0 InsA N-terminal domain UPF0547 PF10571.4 EIE83524.1 - 0.065 12.9 3.4 0.34 10.6 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Terminase_GpA PF05876.7 EIE83524.1 - 0.093 11.0 0.5 0.11 10.8 0.3 1.0 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) TF_Zn_Ribbon PF08271.7 EIE83524.1 - 0.11 11.7 1.0 0.41 9.9 0.7 1.9 1 1 0 1 1 1 0 TFIIB zinc-binding zinc_ribbon_4 PF13717.1 EIE83524.1 - 0.18 11.5 2.0 1.2 8.8 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 EIE83524.1 - 0.24 10.6 0.3 0.24 10.6 0.2 1.8 2 0 0 2 2 2 0 zinc-ribbon domain DNA_RNApol_7kD PF03604.8 EIE83524.1 - 0.49 9.8 3.8 2.9 7.4 0.1 2.3 2 1 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zf-NADH-PPase PF09297.6 EIE83524.1 - 2.5 7.6 5.5 2.1 7.9 1.0 2.2 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Choline_transpo PF04515.7 EIE83525.1 - 4.3e-39 134.1 29.2 7.4e-39 133.4 20.2 1.3 1 0 0 1 1 1 1 Plasma-membrane choline transporter Menin PF05053.8 EIE83525.1 - 0.13 10.4 0.2 0.18 9.9 0.1 1.1 1 0 0 1 1 1 0 Menin PspB PF06667.7 EIE83525.1 - 1.1 9.2 0.0 1.1 9.2 0.0 3.2 3 0 0 3 3 3 0 Phage shock protein B E1-E2_ATPase PF00122.15 EIE83526.1 - 7.4e-31 106.9 0.4 7.4e-31 106.9 0.3 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EIE83526.1 - 1.3e-15 58.4 0.0 1e-14 55.4 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EIE83526.1 - 1.6e-15 57.8 0.1 3.7e-15 56.6 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EIE83526.1 - 0.016 15.1 0.0 0.035 14.0 0.0 1.5 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EIE83526.1 - 0.04 13.4 0.1 0.13 11.7 0.0 1.8 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase UBX PF00789.15 EIE83527.1 - 2e-11 43.7 0.5 6.4e-11 42.1 0.0 2.1 2 0 0 2 2 2 1 UBX domain zf-C2H2_2 PF12756.2 EIE83527.1 - 0.065 13.3 1.9 0.2 11.8 0.2 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Crust_neurohorm PF01147.12 EIE83527.1 - 0.066 12.5 0.0 0.14 11.4 0.0 1.6 1 0 0 1 1 1 0 Crustacean CHH/MIH/GIH neurohormone family zf-C2H2 PF00096.21 EIE83527.1 - 0.13 12.6 0.6 0.25 11.7 0.0 1.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type LRR_4 PF12799.2 EIE83528.1 - 4e-06 26.3 0.0 0.027 14.0 0.0 4.6 2 1 3 5 5 5 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EIE83528.1 - 5.3e-06 25.9 2.0 0.053 13.6 0.0 5.2 6 0 0 6 6 6 1 Leucine Rich repeat F-box-like PF12937.2 EIE83528.1 - 5.2e-05 22.8 0.7 0.00011 21.8 0.0 1.9 2 0 0 2 2 2 1 F-box-like LRR_8 PF13855.1 EIE83528.1 - 0.00017 21.3 1.0 0.035 13.8 0.3 3.6 3 1 1 4 4 4 2 Leucine rich repeat LRR_1 PF00560.28 EIE83528.1 - 0.026 14.5 6.5 3.4 8.0 0.0 4.9 5 1 0 5 5 5 0 Leucine Rich Repeat LRR_7 PF13504.1 EIE83528.1 - 0.86 10.0 8.4 13 6.4 0.1 5.3 5 1 0 5 5 5 0 Leucine rich repeat Y_phosphatase3 PF13350.1 EIE83529.1 - 1.8e-22 80.3 0.7 4.2e-16 59.6 0.0 2.6 1 1 2 3 3 3 2 Tyrosine phosphatase family Y_phosphatase PF00102.22 EIE83529.1 - 2.7e-06 26.8 0.0 4.3e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.8 EIE83529.1 - 0.00028 20.3 0.0 0.0005 19.4 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family AsiA PF09010.5 EIE83529.1 - 0.00058 19.6 0.0 0.0021 17.8 0.0 1.9 2 0 0 2 2 2 1 Anti-Sigma Factor A DSPc PF00782.15 EIE83529.1 - 0.0052 16.3 0.0 0.01 15.4 0.0 1.5 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 EIE83529.1 - 0.038 14.0 0.1 0.1 12.6 0.0 1.7 1 1 1 2 2 2 0 Inositol hexakisphosphate RNA_pol_Rpb6 PF01192.17 EIE83530.1 - 4.4e-20 71.1 0.1 5.8e-20 70.7 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb6 Oxysterol_BP PF01237.13 EIE83531.1 - 0.052 12.0 0.0 0.052 12.0 0.0 1.2 1 0 0 1 1 1 0 Oxysterol-binding protein Ribosomal_L13 PF00572.13 EIE83532.1 - 5.5e-50 168.7 0.1 6.7e-50 168.4 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L13 DUF2340 PF10209.4 EIE83532.1 - 0.12 12.5 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2340) An_peroxidase PF03098.10 EIE83533.1 - 1.2e-71 241.6 0.1 3.3e-69 233.6 0.0 2.4 1 1 0 1 1 1 1 Animal haem peroxidase Ribosomal_L11 PF00298.14 EIE83534.1 - 1.2e-28 99.0 1.4 1.2e-28 99.0 1.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.9 EIE83534.1 - 1.7e-26 91.4 0.3 2.6e-26 90.8 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain TrbC_Ftype PF09673.5 EIE83534.1 - 0.012 15.1 0.0 0.018 14.6 0.0 1.2 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein FlgN PF05130.7 EIE83536.1 - 0.0029 17.8 0.4 0.0068 16.6 0.3 1.6 1 0 0 1 1 1 1 FlgN protein Spc97_Spc98 PF04130.8 EIE83536.1 - 0.0053 15.1 0.1 0.0074 14.6 0.1 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family SlyX PF04102.7 EIE83536.1 - 0.018 15.4 3.2 0.11 12.9 0.4 2.8 2 0 0 2 2 2 0 SlyX Syntaxin PF00804.20 EIE83536.1 - 0.039 14.1 3.8 0.12 12.6 1.2 2.8 2 1 0 2 2 2 0 Syntaxin MCPsignal PF00015.16 EIE83536.1 - 0.066 12.7 0.1 0.12 11.8 0.1 1.4 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain NPV_P10 PF05531.7 EIE83536.1 - 0.082 13.1 4.3 0.89 9.8 0.2 3.3 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein MscS_porin PF12795.2 EIE83536.1 - 0.18 11.0 3.9 0.11 11.7 1.1 1.9 2 1 0 2 2 2 0 Mechanosensitive ion channel porin domain ALIX_LYPXL_bnd PF13949.1 EIE83536.1 - 0.38 9.6 10.9 0.11 11.3 3.4 2.4 1 1 1 3 3 3 0 ALIX V-shaped domain binding to HIV Fib_alpha PF08702.5 EIE83536.1 - 0.98 9.5 6.5 0.92 9.6 1.2 2.5 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family KxDL PF10241.4 EIE83536.1 - 1.1 9.2 4.1 0.53 10.2 0.7 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein TBPIP PF07106.8 EIE83536.1 - 1.5 8.3 8.4 1.1 8.8 2.1 2.6 3 1 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF1664 PF07889.7 EIE83536.1 - 2.9 7.6 7.0 3 7.6 1.0 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Seryl_tRNA_N PF02403.17 EIE83536.1 - 3.4 7.7 8.4 1.4 9.0 2.0 2.8 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain FlaC_arch PF05377.6 EIE83536.1 - 3.6 7.5 7.3 5.7 6.9 0.7 3.6 4 0 0 4 4 3 0 Flagella accessory protein C (FlaC) IncA PF04156.9 EIE83536.1 - 5.6 6.5 9.8 0.82 9.2 2.8 2.3 2 2 0 2 2 2 0 IncA protein Pkinase_Tyr PF07714.12 EIE83537.1 - 1.8e-16 60.0 0.0 4e-16 58.8 0.0 1.6 1 1 1 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.20 EIE83537.1 - 2.4e-16 59.6 0.1 2e-15 56.6 0.0 2.0 1 1 1 2 2 2 1 Protein kinase domain APH PF01636.18 EIE83537.1 - 0.0055 16.4 0.1 0.0097 15.6 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF925 PF06042.6 EIE83538.1 - 0.16 11.5 1.4 0.18 11.3 0.9 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF925) COX6A PF02046.10 EIE83538.1 - 0.84 9.5 2.8 16 5.4 0.0 2.1 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIa SieB PF14163.1 EIE83540.1 - 6.3 6.3 10.8 0.25 10.9 2.1 2.4 2 1 1 3 3 3 0 Superinfection exclusion protein B DUF4418 PF14387.1 EIE83540.1 - 8.8 6.0 16.4 45 3.7 11.0 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4418) Daxx PF03344.10 EIE83541.1 - 1.3e-05 23.9 17.0 1.7e-05 23.5 11.8 1.1 1 0 0 1 1 1 1 Daxx Family DUF1510 PF07423.6 EIE83541.1 - 0.00084 18.7 14.9 0.0013 18.2 10.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) SKG6 PF08693.5 EIE83541.1 - 0.0082 15.4 0.3 0.024 13.9 0.2 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Rick_17kDa_Anti PF05433.10 EIE83541.1 - 0.035 13.7 6.8 0.065 12.9 4.7 1.4 1 0 0 1 1 1 0 Glycine zipper 2TM domain SDA1 PF05285.7 EIE83541.1 - 0.065 12.5 21.9 0.089 12.0 15.2 1.2 1 0 0 1 1 1 0 SDA1 Adeno_E3_CR2 PF02439.10 EIE83541.1 - 0.11 12.1 0.1 0.2 11.2 0.1 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Gly-zipper_Omp PF13488.1 EIE83541.1 - 0.62 9.7 9.7 1.3 8.6 6.7 1.5 1 1 0 1 1 1 0 Glycine zipper Gly-zipper_YMGG PF13441.1 EIE83541.1 - 0.95 9.0 8.9 1.6 8.3 6.2 1.3 1 0 0 1 1 1 0 YMGG-like Gly-zipper DUF2201_N PF13203.1 EIE83541.1 - 6.8 5.7 7.7 11 5.1 5.3 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain ATP-synt_D PF01813.12 EIE83542.1 - 3.5e-66 222.5 3.9 4.5e-66 222.1 2.7 1.1 1 0 0 1 1 1 1 ATP synthase subunit D Prismane PF03063.15 EIE83542.1 - 0.11 10.8 0.1 0.15 10.3 0.1 1.1 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Asp PF00026.18 EIE83543.1 - 6.9e-75 252.2 15.3 2e-74 250.7 10.6 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIE83543.1 - 3.7e-11 43.2 3.1 3.9e-09 36.6 0.3 3.9 1 1 2 3 3 3 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EIE83543.1 - 0.0038 16.7 0.2 0.021 14.3 0.2 2.2 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 EIE83543.1 - 0.0062 17.0 3.9 0.29 11.6 0.1 3.5 2 2 0 2 2 2 1 Aspartyl protease Asp PF00026.18 EIE83544.1 - 7.3e-17 61.5 0.0 1.5e-16 60.5 0.0 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease DUF1802 PF08819.6 EIE83546.1 - 0.011 15.2 0.2 0.015 14.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1802) Adenylsucc_synt PF00709.16 EIE83547.1 - 1.5e-136 455.4 0.0 4.4e-135 450.5 0.0 2.0 1 1 0 1 1 1 1 Adenylosuccinate synthetase SWIRM PF04433.12 EIE83548.1 - 2.1e-09 37.3 0.0 5.5e-09 36.0 0.0 1.6 2 0 0 2 2 2 1 SWIRM domain PMSR PF01625.16 EIE83549.1 - 5e-28 97.9 1.0 5.5e-28 97.7 0.7 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Svf1 PF08622.5 EIE83550.1 - 1.8e-86 290.1 9.1 2.1e-86 289.8 6.3 1.1 1 0 0 1 1 1 1 Svf1-like eIF-5a PF01287.15 EIE83550.1 - 0.08 12.9 1.8 0.21 11.5 1.3 1.7 1 0 0 1 1 1 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold FAM177 PF14774.1 EIE83550.1 - 0.25 11.2 2.9 29 4.5 0.3 3.1 3 0 0 3 3 3 0 FAM177 family PIP5K PF01504.13 EIE83551.1 - 5.7e-20 71.4 0.8 1.5e-19 70.1 0.6 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Oxysterol_BP PF01237.13 EIE83552.1 - 5.7e-83 278.3 1.5 1.9e-80 270.0 1.0 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein Ribosomal_60s PF00428.14 EIE83553.1 - 1.1e-25 89.8 14.4 1.2e-25 89.6 10.0 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein MIR PF02815.14 EIE83554.1 - 2.2e-13 50.1 0.1 3.4e-11 43.0 0.0 2.2 1 1 1 2 2 2 2 MIR domain Ins145_P3_rec PF08709.6 EIE83554.1 - 9.8e-05 21.4 0.0 0.0072 15.3 0.0 2.1 1 1 1 2 2 2 2 Inositol 1,4,5-trisphosphate/ryanodine receptor RicinB_lectin_2 PF14200.1 EIE83554.1 - 0.12 12.7 0.7 0.37 11.1 0.5 1.8 2 1 0 2 2 2 0 Ricin-type beta-trefoil lectin domain-like Med26 PF08711.6 EIE83555.1 - 1.3e-13 50.1 0.0 3.1e-13 49.0 0.0 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Peptidase_C12 PF01088.16 EIE83555.1 - 0.25 10.4 5.4 0.33 10.0 2.8 1.9 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase, family 1 DUF4364 PF14277.1 EIE83555.1 - 0.28 10.7 2.8 2.3 7.7 0.1 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4364) ATP-synt_DE_N PF02823.11 EIE83556.1 - 3.2e-19 68.4 0.2 5.2e-19 67.7 0.1 1.4 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain ATP-synt_ab PF00006.20 EIE83557.1 - 8.8e-64 214.9 0.0 1.8e-63 213.8 0.0 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.18 EIE83557.1 - 4e-25 87.8 2.6 8.1e-25 86.8 1.4 1.9 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain ATP-synt_ab_C PF00306.22 EIE83557.1 - 4.9e-24 84.9 1.3 8.1e-24 84.2 0.9 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain MobB PF03205.9 EIE83557.1 - 0.0024 17.5 0.1 0.94 9.1 0.0 3.1 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 EIE83557.1 - 0.0038 16.9 0.0 0.0076 15.9 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase NACHT PF05729.7 EIE83557.1 - 0.0064 16.1 0.1 0.015 14.9 0.0 1.6 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 EIE83557.1 - 0.012 15.6 0.2 0.046 13.7 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 EIE83557.1 - 0.015 15.4 0.0 0.11 12.5 0.0 2.3 2 1 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EIE83557.1 - 0.019 13.8 1.0 0.033 13.0 0.1 1.7 2 0 0 2 2 2 0 NB-ARC domain KaiC PF06745.8 EIE83557.1 - 0.039 13.0 0.1 0.081 12.0 0.1 1.6 1 0 0 1 1 1 0 KaiC AAA PF00004.24 EIE83557.1 - 0.04 14.1 0.1 0.5 10.5 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EIE83557.1 - 0.041 13.2 0.1 0.15 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 EIE83557.1 - 0.061 12.5 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 RNA_helicase PF00910.17 EIE83557.1 - 0.12 12.5 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Glyco_hydro_72 PF03198.9 EIE83558.1 - 3.6e-131 436.8 1.6 4.8e-131 436.4 1.1 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 EIE83558.1 - 2.5e-12 47.0 1.7 7.9e-12 45.5 1.1 1.9 1 0 0 1 1 1 1 X8 domain Pkinase PF00069.20 EIE83559.1 - 3.2e-60 203.4 0.1 9.8e-57 192.0 0.0 2.6 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIE83559.1 - 1.3e-27 96.4 0.0 2.3e-25 89.1 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EIE83559.1 - 2.7e-06 26.5 0.0 4.8e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like KA1 PF02149.14 EIE83559.1 - 3.2e-05 23.2 0.2 5.7e-05 22.4 0.1 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 RIO1 PF01163.17 EIE83559.1 - 0.00024 20.5 0.1 0.00053 19.3 0.1 1.5 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 EIE83559.1 - 0.0027 16.8 0.1 0.0054 15.8 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIE83559.1 - 0.076 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 EIE83559.1 - 0.6 9.6 4.0 0.46 10.0 0.1 2.5 3 0 0 3 3 3 0 Choline/ethanolamine kinase UMP1 PF05348.6 EIE83560.1 - 8e-36 122.8 0.3 9.3e-36 122.6 0.2 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Pkinase PF00069.20 EIE83561.1 - 3.7e-60 203.2 0.0 6.1e-60 202.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE83561.1 - 1.9e-31 109.1 0.0 2.8e-31 108.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EIE83561.1 - 4.4e-07 29.9 0.2 1e-06 28.7 0.1 1.7 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 EIE83561.1 - 1.3e-06 27.5 0.0 2.1e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like SR-25 PF10500.4 EIE83561.1 - 0.81 9.1 14.4 1.2 8.5 10.0 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SPRY PF00622.23 EIE83562.1 - 7.4e-16 58.3 0.0 1.5e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 SPRY domain zf-C3HC4_3 PF13920.1 EIE83562.1 - 3.1e-05 23.5 0.3 9.2e-05 22.0 0.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIE83562.1 - 0.00085 19.2 1.1 0.0031 17.4 0.7 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ANTH PF07651.11 EIE83563.1 - 1.7e-47 161.4 1.7 2.4e-47 160.9 1.2 1.2 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.15 EIE83563.1 - 5.4e-09 35.9 0.2 2.1e-08 34.0 0.0 2.1 2 0 0 2 2 2 1 ENTH domain HLH PF00010.21 EIE83564.1 - 5.3e-14 51.6 0.2 1.4e-13 50.3 0.2 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain IncA PF04156.9 EIE83564.1 - 0.0008 19.0 0.3 0.0012 18.4 0.2 1.2 1 0 0 1 1 1 1 IncA protein IF4E PF01652.13 EIE83564.1 - 0.018 14.5 0.0 0.063 12.8 0.0 1.7 1 1 0 1 1 1 0 Eukaryotic initiation factor 4E Vasculin PF15337.1 EIE83564.1 - 0.36 11.3 0.1 0.36 11.3 0.1 2.5 3 0 0 3 3 3 0 Vascular protein family Vasculin-like 1 Striatin PF08232.7 EIE83564.1 - 3.7 7.8 8.9 0.48 10.7 1.3 2.1 1 1 1 2 2 2 0 Striatin family SBP PF03110.9 EIE83565.1 - 0.041 14.0 1.2 0.055 13.6 0.8 1.5 1 1 0 1 1 1 0 SBP domain GMC_oxred_N PF00732.14 EIE83566.1 - 4.8e-40 137.5 4.6 7.2e-35 120.5 0.2 2.2 1 1 1 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.8 EIE83566.1 - 1.1e-25 90.5 0.0 2.3e-25 89.5 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EIE83566.1 - 1.4e-10 40.6 1.9 2.3e-05 23.4 0.8 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EIE83566.1 - 3.4e-07 29.5 1.8 0.0054 15.6 0.8 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIE83566.1 - 0.00026 20.9 3.6 0.00031 20.6 1.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GDI PF00996.13 EIE83566.1 - 0.0003 19.2 1.8 0.00036 18.9 0.0 2.0 3 0 0 3 3 3 1 GDP dissociation inhibitor HI0933_like PF03486.9 EIE83566.1 - 0.00063 18.3 3.2 0.0027 16.2 0.4 2.5 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox_2 PF07992.9 EIE83566.1 - 0.0014 18.5 0.5 0.017 15.0 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EIE83566.1 - 0.0031 16.4 0.2 0.88 8.3 0.1 2.4 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_3 PF01494.14 EIE83566.1 - 0.013 14.5 0.3 0.027 13.5 0.2 1.5 1 0 0 1 1 1 0 FAD binding domain ApbA PF02558.11 EIE83566.1 - 0.015 14.7 0.1 0.034 13.5 0.1 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.7 EIE83566.1 - 0.046 12.6 0.2 0.32 9.8 0.1 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.12 EIE83566.1 - 0.056 12.5 0.1 0.15 11.1 0.1 1.7 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.1 EIE83566.1 - 0.093 12.7 0.1 7.2 6.6 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF3500 PF12006.3 EIE83566.1 - 0.12 11.2 0.1 0.25 10.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3500) FAD_oxidored PF12831.2 EIE83566.1 - 1.7 7.6 3.5 1.6 7.7 1.4 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase COX6B PF02297.12 EIE83567.1 - 3e-18 65.6 6.4 3.5e-18 65.3 4.4 1.0 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb APOBEC_C PF05240.9 EIE83567.1 - 0.011 15.0 0.6 0.017 14.5 0.4 1.3 1 0 0 1 1 1 0 APOBEC-like C-terminal domain UPF0203 PF05254.7 EIE83567.1 - 2.5 8.0 7.0 9.1 6.2 0.3 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) Raffinose_syn PF05691.7 EIE83568.1 - 3e-51 173.8 1.3 3.4e-41 140.6 0.3 2.9 1 1 1 2 2 2 2 Raffinose synthase or seed imbibition protein Sip1 DUF974 PF06159.8 EIE83570.1 - 2.1e-50 171.4 0.0 1.6e-24 86.7 0.0 2.5 1 1 1 2 2 2 2 Protein of unknown function (DUF974) Transglut_C PF00927.17 EIE83570.1 - 1.1e-05 25.3 0.1 0.0083 16.1 0.0 2.5 2 0 0 2 2 2 2 Transglutaminase family, C-terminal ig like domain Utp21 PF04192.7 EIE83572.1 - 7.6e-60 201.9 5.2 1.2e-59 201.2 3.6 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 EIE83572.1 - 1.1e-32 110.7 14.3 1.7e-08 34.0 0.4 9.9 10 0 0 10 10 10 5 WD domain, G-beta repeat Nup160 PF11715.3 EIE83572.1 - 7.4e-09 34.2 9.5 0.0022 16.2 0.1 4.5 4 2 0 4 4 4 3 Nucleoporin Nup120/160 PQQ_2 PF13360.1 EIE83572.1 - 0.00015 21.3 0.1 1.5 8.2 0.0 3.5 2 2 0 2 2 2 2 PQQ-like domain Nucleoporin_N PF08801.6 EIE83572.1 - 0.00025 19.9 2.1 0.38 9.4 0.0 3.3 2 1 1 3 3 3 2 Nup133 N terminal like Cytochrom_D1 PF02239.11 EIE83572.1 - 0.017 13.4 0.6 0.3 9.3 0.0 2.7 3 0 0 3 3 3 0 Cytochrome D1 heme domain FAM131 PF15010.1 EIE83572.1 - 0.1 12.3 0.6 0.18 11.5 0.4 1.4 1 0 0 1 1 1 0 Putative cell signalling Pkinase PF00069.20 EIE83573.1 - 6.3e-27 94.3 0.0 7.3e-27 94.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE83573.1 - 1.7e-06 27.3 0.0 2e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase YrbL-PhoP_reg PF10707.4 EIE83573.1 - 0.0077 15.5 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.9 EIE83573.1 - 0.0088 15.1 0.0 0.013 14.6 0.0 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIE83573.1 - 0.026 14.2 0.0 1.9 8.1 0.0 2.3 1 1 0 2 2 2 0 Phosphotransferase enzyme family DUF843 PF05814.6 EIE83574.1 - 0.17 11.6 0.1 0.33 10.7 0.1 1.4 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF843) BBP1_N PF15271.1 EIE83575.1 - 0.067 13.5 1.3 0.22 11.8 0.3 1.9 2 0 0 2 2 2 0 Spindle pole body component BBP1, Mps2-binding protein LETM1 PF07766.8 EIE83576.1 - 6.1e-28 97.6 1.8 1.3e-25 89.9 1.3 2.0 1 1 0 1 1 1 1 LETM1-like protein SDH_alpha PF03313.10 EIE83576.1 - 0.023 13.7 0.0 0.036 13.0 0.0 1.2 1 0 0 1 1 1 0 Serine dehydratase alpha chain Ribosomal_L21e PF01157.13 EIE83577.1 - 4.8e-43 145.0 4.7 6.7e-43 144.5 3.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L21e DUF1989 PF09347.5 EIE83577.1 - 0.0022 17.4 0.0 0.0029 17.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) DUF3865 PF12981.2 EIE83577.1 - 0.07 12.9 0.1 0.088 12.5 0.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3865) Surface_Ag_2 PF01617.12 EIE83577.1 - 0.084 12.0 0.2 0.1 11.8 0.1 1.3 1 0 0 1 1 1 0 Surface antigen LRS4 PF10422.4 EIE83577.1 - 0.098 11.9 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 Ribosomal_S4 PF00163.14 EIE83578.1 - 4.2e-28 97.5 1.0 7.6e-28 96.7 0.7 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 EIE83578.1 - 3.1e-13 48.9 1.4 3.1e-13 48.9 1.0 2.4 3 0 0 3 3 3 1 S4 domain 7tm_2 PF00002.19 EIE83579.1 - 0.0061 15.6 13.3 0.0094 15.0 9.3 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) YajC PF02699.10 EIE83579.1 - 4.3 7.0 7.3 21 4.8 0.0 3.5 4 0 0 4 4 4 0 Preprotein translocase subunit GFO_IDH_MocA PF01408.17 EIE83581.1 - 6.5e-28 97.6 0.0 9.7e-28 97.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.12 EIE83581.1 - 1.7e-06 28.3 0.0 3.3e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 EIE83581.1 - 9.3e-05 22.5 0.1 0.00019 21.5 0.0 1.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.19 EIE83581.1 - 0.00064 20.0 0.0 0.0013 19.0 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_3 PF03447.11 EIE83581.1 - 0.0011 19.4 0.0 0.0018 18.6 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain GFO_IDH_MocA_C PF02894.12 EIE83581.1 - 0.022 14.5 0.0 0.05 13.3 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain 2-Hacid_dh_C PF02826.14 EIE83581.1 - 0.038 13.1 0.0 0.059 12.5 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IF-2B PF01008.12 EIE83582.1 - 6.3e-80 268.1 0.0 6.3e-80 268.1 0.0 1.4 2 0 0 2 2 2 1 Initiation factor 2 subunit family Macoilin PF09726.4 EIE83582.1 - 0.099 10.9 10.2 0.12 10.6 7.0 1.1 1 0 0 1 1 1 0 Transmembrane protein hemP PF10636.4 EIE83582.1 - 0.12 11.9 0.2 0.91 9.1 0.1 2.1 2 0 0 2 2 2 0 Hemin uptake protein hemP Med25_NR-box PF11244.3 EIE83582.1 - 0.2 12.1 6.1 0.54 10.7 4.2 1.6 1 0 0 1 1 1 0 Mediator complex subunit 25 C-terminal NR box-containing MIP-T3 PF10243.4 EIE83582.1 - 4.2 5.7 33.5 5.9 5.2 23.2 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Asp-B-Hydro_N PF05279.6 EIE83582.1 - 6.5 6.5 16.2 10 5.8 11.3 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Ribosomal_L32p PF01783.18 EIE83583.1 - 4e-14 52.5 8.5 5.3e-14 52.1 5.9 1.2 1 0 0 1 1 1 1 Ribosomal L32p protein family zinc-ribbons_6 PF07191.7 EIE83583.1 - 0.0064 16.2 2.7 0.0084 15.8 1.6 1.4 1 1 0 1 1 1 1 zinc-ribbons DZR PF12773.2 EIE83583.1 - 0.0093 15.7 1.5 0.014 15.1 1.1 1.4 1 0 0 1 1 1 1 Double zinc ribbon DUF1272 PF06906.6 EIE83583.1 - 0.014 15.1 0.9 0.024 14.4 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Zn-ribbon_8 PF09723.5 EIE83583.1 - 0.019 14.8 2.4 0.23 11.4 0.2 2.3 1 1 1 2 2 2 0 Zinc ribbon domain zf-ribbon_3 PF13248.1 EIE83583.1 - 0.037 13.2 2.9 0.96 8.7 0.3 2.2 2 0 0 2 2 2 0 zinc-ribbon domain NRDD PF13597.1 EIE83583.1 - 0.055 11.5 0.6 0.06 11.4 0.4 1.1 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase Prok-RING_1 PF14446.1 EIE83583.1 - 0.063 13.0 1.5 0.31 10.8 0.8 1.9 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-C4_Topoisom PF01396.14 EIE83583.1 - 0.07 12.6 5.6 0.96 8.9 0.5 2.4 1 1 1 2 2 2 0 Topoisomerase DNA binding C4 zinc finger UPF0547 PF10571.4 EIE83583.1 - 0.076 12.7 2.4 6.3 6.5 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Tnp_zf-ribbon_2 PF13842.1 EIE83583.1 - 0.093 13.1 2.4 0.17 12.3 1.6 1.5 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon DUF2752 PF10825.3 EIE83583.1 - 0.1 12.6 1.1 0.14 12.1 0.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2752) TniQ PF06527.6 EIE83583.1 - 0.11 12.6 1.2 1.8 8.8 0.9 2.0 1 1 0 1 1 1 0 TniQ PolC_DP2 PF03833.8 EIE83583.1 - 0.14 9.7 1.0 0.16 9.6 0.7 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zinc_ribbon_2 PF13240.1 EIE83583.1 - 0.18 11.3 2.6 9 5.9 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain GFA PF04828.9 EIE83583.1 - 0.23 11.4 3.0 0.98 9.4 2.1 2.2 1 1 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme DUF1610 PF07754.6 EIE83583.1 - 0.33 11.1 2.9 5.4 7.2 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) zf-ISL3 PF14690.1 EIE83583.1 - 0.39 10.7 5.2 4.4 7.4 0.4 2.7 2 1 1 3 3 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 TFIIS_C PF01096.13 EIE83583.1 - 1.2 8.8 4.7 0.8 9.3 0.3 2.2 1 1 1 2 2 2 0 Transcription factor S-II (TFIIS) zf-RING_4 PF14570.1 EIE83583.1 - 1.2 8.7 4.8 4.2 7.0 0.1 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.1 EIE83583.1 - 1.5 8.9 5.7 13 5.8 3.9 2.1 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) TF_Zn_Ribbon PF08271.7 EIE83583.1 - 2.1 7.7 4.4 4.4 6.6 0.3 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding RhoGAP PF00620.22 EIE83584.1 - 6.8e-33 113.4 0.2 1.1e-32 112.7 0.1 1.3 1 0 0 1 1 1 1 RhoGAP domain EF-hand_7 PF13499.1 EIE83585.1 - 4e-14 52.5 3.1 5.8e-14 51.9 2.2 1.4 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 EIE83585.1 - 3.3e-12 44.7 1.7 0.00019 20.4 0.1 3.1 2 1 1 3 3 3 3 EF hand EF-hand_6 PF13405.1 EIE83585.1 - 2e-11 42.7 3.7 4.1e-06 26.2 0.5 3.1 2 1 1 3 3 3 3 EF-hand domain EF-hand_5 PF13202.1 EIE83585.1 - 2e-07 30.0 2.3 0.0088 15.3 0.1 3.0 2 1 1 3 3 3 2 EF hand EF-hand_8 PF13833.1 EIE83585.1 - 0.00013 21.4 4.8 0.0045 16.5 2.8 2.9 1 1 1 2 2 2 1 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EIE83585.1 - 0.0045 17.0 0.1 0.027 14.5 0.1 2.1 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region LXG PF04740.7 EIE83585.1 - 0.085 12.6 0.0 0.094 12.4 0.0 1.1 1 0 0 1 1 1 0 LXG domain of WXG superfamily ECH PF00378.15 EIE83587.1 - 3.8e-28 98.2 0.0 4.6e-28 97.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 EIE83587.1 - 0.0071 16.1 0.1 1.2 8.8 0.1 2.1 2 0 0 2 2 2 2 Peptidase family S49 NAD_binding_1 PF00175.16 EIE83588.1 - 7.5e-29 100.4 0.0 1.3e-28 99.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EIE83588.1 - 1.2e-12 47.8 0.0 6e-12 45.5 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EIE83588.1 - 1.4e-08 34.7 0.0 5.3e-05 23.1 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain Peptidase_S10 PF00450.17 EIE83589.1 - 4.3e-40 138.1 1.2 4.7e-30 105.0 0.1 3.5 2 1 1 3 3 3 3 Serine carboxypeptidase Rhabdo_glycop PF00974.13 EIE83589.1 - 0.0018 16.6 0.0 0.012 13.9 0.0 1.9 2 0 0 2 2 2 1 Rhabdovirus spike glycoprotein DUF2684 PF10885.3 EIE83589.1 - 0.011 15.5 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2684) DUF4149 PF13664.1 EIE83589.1 - 0.087 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4149) DUF2951 PF11166.3 EIE83589.1 - 0.095 12.5 0.3 0.38 10.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) Ribosomal_60s PF00428.14 EIE83591.1 - 1.4e-26 92.6 15.0 1.6e-26 92.4 10.4 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein Aldedh PF00171.17 EIE83591.1 - 0.032 12.5 0.2 0.036 12.4 0.1 1.1 1 0 0 1 1 1 0 Aldehyde dehydrogenase family Peptidase_M1 PF01433.15 EIE83592.1 - 5.3e-79 266.1 0.0 6.7e-79 265.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 Peptidase_MA_2 PF13485.1 EIE83592.1 - 2.7e-14 53.3 0.0 4.5e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily Peptidase_M61 PF05299.7 EIE83592.1 - 0.41 10.6 2.0 2.8 7.9 1.4 2.3 1 1 0 1 1 1 0 M61 glycyl aminopeptidase Abhydrolase_3 PF07859.8 EIE83593.1 - 3.5e-26 92.0 0.0 2.1e-17 63.3 0.0 2.8 2 1 0 2 2 2 2 alpha/beta hydrolase fold RVT_1 PF00078.22 EIE83594.1 - 4e-17 62.2 0.0 3.8e-08 32.9 0.0 2.4 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EIE83594.1 - 0.15 11.6 1.2 0.41 10.2 0.1 2.3 2 1 0 2 2 2 0 Endonuclease-reverse transcriptase YPEB PF14620.1 EIE83595.1 - 0.032 13.2 2.6 0.049 12.6 1.8 1.3 1 0 0 1 1 1 0 YpeB sporulation TMF_TATA_bd PF12325.3 EIE83595.1 - 0.037 13.7 1.8 0.33 10.6 0.7 2.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding FtsK_SpoIIIE PF01580.13 EIE83595.1 - 0.053 13.0 0.1 0.085 12.3 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family BRICHOS PF04089.9 EIE83595.1 - 0.12 12.2 1.5 0.2 11.5 0.2 2.0 2 0 0 2 2 2 0 BRICHOS domain DUF2296 PF10058.4 EIE83595.1 - 0.16 11.7 1.5 0.38 10.5 1.0 1.6 1 0 0 1 1 1 0 Predicted integral membrane metal-binding protein (DUF2296) Ima1_N PF09779.4 EIE83595.1 - 1.6 9.2 6.4 7.2 7.1 3.5 2.8 2 1 0 2 2 2 0 Ima1 N-terminal domain ADK_lid PF05191.9 EIE83595.1 - 5.5 6.7 6.1 9.4 6.0 0.3 2.2 1 1 1 2 2 2 0 Adenylate kinase, active site lid HTH_Tnp_Tc3_2 PF01498.13 EIE83596.1 - 2.4e-16 59.5 1.1 5.2e-16 58.4 0.8 1.6 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.1 EIE83596.1 - 5.4e-08 32.9 0.2 2.6e-07 30.7 0.0 2.0 2 0 0 2 2 2 1 Winged helix-turn helix DDE_3 PF13358.1 EIE83596.1 - 4.8e-05 23.1 0.0 8.4e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_23 PF13384.1 EIE83596.1 - 0.00063 19.3 0.0 0.0019 17.8 0.0 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.1 EIE83596.1 - 0.0014 18.6 0.0 0.004 17.1 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_17 PF12728.2 EIE83596.1 - 0.0017 18.5 0.4 0.16 12.2 0.0 3.1 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_24 PF13412.1 EIE83596.1 - 0.0031 16.8 0.0 0.082 12.3 0.0 2.6 3 0 0 3 3 3 1 Winged helix-turn-helix DNA-binding SpoIIID PF12116.3 EIE83596.1 - 0.015 15.2 0.0 0.031 14.1 0.0 1.6 1 0 0 1 1 1 0 Stage III sporulation protein D HTH_38 PF13936.1 EIE83596.1 - 0.019 14.5 0.0 0.045 13.3 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.1 EIE83596.1 - 0.025 15.3 0.0 0.025 15.3 0.0 3.0 2 2 1 3 3 3 0 Homeodomain-like domain HTH_IclR PF09339.5 EIE83596.1 - 0.042 13.4 0.0 0.076 12.6 0.0 1.3 1 0 0 1 1 1 0 IclR helix-turn-helix domain MerR PF00376.18 EIE83596.1 - 0.064 12.8 0.2 4.3 6.9 0.0 2.5 2 0 0 2 2 2 0 MerR family regulatory protein DUF273 PF03314.9 EIE83596.1 - 0.065 12.5 0.2 2.2 7.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF273 HTH_AsnC-type PF13404.1 EIE83596.1 - 0.11 12.0 0.0 0.75 9.3 0.0 2.2 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain HTH_7 PF02796.10 EIE83596.1 - 0.16 11.8 0.8 4 7.3 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase Asp PF00026.18 EIE83597.1 - 1.3e-70 238.2 5.9 1.5e-70 237.9 4.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 EIE83597.1 - 1e-07 31.6 0.0 2e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal TAXi_N PF14543.1 EIE83597.1 - 1.3e-06 28.4 0.8 5.1e-06 26.5 0.1 2.3 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EIE83597.1 - 0.00027 21.3 0.9 0.13 12.8 0.0 3.1 3 1 0 3 3 3 2 Aspartyl protease RVP PF00077.15 EIE83597.1 - 0.031 14.2 0.1 1.3 8.9 0.0 2.6 2 0 0 2 2 2 0 Retroviral aspartyl protease F-box-like PF12937.2 EIE83598.1 - 2.4e-06 27.1 1.2 4.3e-06 26.3 0.1 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EIE83598.1 - 0.0012 18.4 0.0 0.012 15.2 0.0 2.3 2 0 0 2 2 2 1 F-box domain PRANC PF09372.5 EIE83598.1 - 0.0092 15.9 0.1 0.025 14.5 0.0 1.7 1 0 0 1 1 1 1 PRANC domain FOP_dimer PF09398.5 EIE83598.1 - 0.098 12.6 0.0 0.58 10.1 0.0 2.0 2 0 0 2 2 2 0 FOP N terminal dimerisation domain Glyco_hydro_28 PF00295.12 EIE83599.1 - 1.4e-46 158.9 17.3 2.2e-46 158.3 12.0 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Ribosomal_L22 PF00237.14 EIE83601.1 - 1.3e-19 70.0 1.2 2.3e-19 69.2 0.8 1.4 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e HSP90 PF00183.13 EIE83602.1 - 8.3e-145 483.1 17.5 3e-144 481.3 12.1 1.7 1 1 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.1 EIE83602.1 - 5.4e-11 42.3 3.4 6.7e-11 41.9 0.1 2.5 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EIE83602.1 - 6.2e-10 38.7 0.1 2.2e-09 37.0 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase RNA_Me_trans PF04252.8 EIE83604.1 - 1.1e-35 122.8 0.0 1.2e-35 122.6 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Pkinase PF00069.20 EIE83605.1 - 5.8e-56 189.5 0.0 7.3e-56 189.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE83605.1 - 9.1e-34 116.6 0.0 1.1e-33 116.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EIE83605.1 - 4.8e-06 25.7 0.2 8.8e-06 24.9 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EIE83605.1 - 0.051 12.9 0.0 0.098 11.9 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL PLDc PF00614.17 EIE83606.1 - 1.9e-15 56.0 3.6 1.3e-11 43.8 0.1 2.9 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 EIE83606.1 - 2e-09 37.2 0.2 2.1e-05 24.2 0.0 3.5 3 0 0 3 3 3 2 PLD-like domain PX PF00787.19 EIE83606.1 - 1.3e-07 31.3 0.1 4.5e-07 29.6 0.0 1.9 2 0 0 2 2 2 1 PX domain ArfGap PF01412.13 EIE83607.1 - 5.3e-34 116.5 2.3 5.9e-34 116.3 1.6 1.1 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf CoA_transf_3 PF02515.12 EIE83608.1 - 5.4e-49 166.0 0.0 1.8e-48 164.3 0.0 1.7 2 0 0 2 2 2 1 CoA-transferase family III ATP1G1_PLM_MAT8 PF02038.11 EIE83608.1 - 0.15 11.0 0.2 0.3 10.1 0.1 1.4 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family Lyase_1 PF00206.15 EIE83609.1 - 5.7e-102 341.0 0.0 8.1e-102 340.5 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 EIE83609.1 - 6.2e-28 96.6 0.1 1.2e-27 95.7 0.1 1.5 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal Cir_N PF10197.4 EIE83610.1 - 1.5e-14 53.6 14.3 1.5e-14 53.6 9.9 2.8 2 1 1 3 3 3 1 N-terminal domain of CBF1 interacting co-repressor CIR CWC25 PF12542.3 EIE83610.1 - 3.3e-12 46.6 3.0 3.3e-12 46.6 2.1 2.1 2 0 0 2 2 2 1 Pre-mRNA splicing factor Gti1_Pac2 PF09729.4 EIE83610.1 - 0.49 10.2 3.8 0.59 9.9 2.6 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family Vma12 PF11712.3 EIE83610.1 - 6.2 6.5 5.6 8.3 6.1 3.8 1.3 1 1 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF3512 PF12024.3 EIE83610.1 - 7.1 5.8 9.5 4.1 6.6 5.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3512) Mito_carr PF00153.22 EIE83611.1 - 4.1e-47 157.8 1.8 1e-22 79.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein CobW_C PF07683.9 EIE83611.1 - 0.076 12.7 0.0 0.67 9.7 0.0 2.1 2 0 0 2 2 2 0 Cobalamin synthesis protein cobW C-terminal domain HECT PF00632.20 EIE83612.1 - 3.8e-95 318.6 0.0 5.7e-95 318.0 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 EIE83612.1 - 1.3e-35 120.8 18.2 3.1e-12 46.1 0.3 3.8 3 0 0 3 3 3 3 WW domain C2 PF00168.25 EIE83612.1 - 3.1e-15 55.7 0.5 3.1e-15 55.7 0.4 2.2 2 0 0 2 2 2 1 C2 domain Porin_3 PF01459.17 EIE83613.1 - 2.9e-70 236.6 3.3 3.3e-70 236.4 2.3 1.0 1 0 0 1 1 1 1 Eukaryotic porin Ldh_1_C PF02866.13 EIE83614.1 - 2.8e-47 160.6 0.1 4e-47 160.1 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 EIE83614.1 - 1.1e-45 154.9 0.0 1.7e-45 154.2 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EIE83614.1 - 1.8e-05 23.6 0.0 2.6e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EIE83614.1 - 0.00021 21.3 0.2 0.00043 20.3 0.0 1.6 2 0 0 2 2 2 1 NADH(P)-binding Semialdhyde_dh PF01118.19 EIE83614.1 - 0.0018 18.5 0.5 0.0067 16.7 0.0 2.1 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 EIE83614.1 - 0.025 14.0 0.0 0.037 13.4 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 EIE83614.1 - 0.15 11.1 1.1 0.82 8.7 0.1 2.4 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Methyltransf_23 PF13489.1 EIE83615.1 - 4e-15 55.8 0.0 6.3e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIE83615.1 - 5e-12 46.1 0.0 1.3e-11 44.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIE83615.1 - 5e-10 39.1 0.0 2.9e-09 36.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIE83615.1 - 1.1e-07 31.2 0.0 2.1e-07 30.2 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EIE83615.1 - 2e-07 31.5 0.0 3.3e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIE83615.1 - 4e-07 30.3 0.0 5.3e-06 26.7 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIE83615.1 - 7e-07 29.6 0.0 1.8e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EIE83615.1 - 1.5e-06 27.3 0.0 9e-06 24.8 0.0 2.1 2 1 0 2 2 2 1 Putative methyltransferase MetW PF07021.7 EIE83615.1 - 0.00013 21.3 0.0 0.00022 20.6 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.9 EIE83615.1 - 0.011 15.1 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain CMAS PF02353.15 EIE83615.1 - 0.012 14.7 0.0 0.02 13.9 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.6 EIE83615.1 - 0.019 13.6 0.0 0.039 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) PCMT PF01135.14 EIE83615.1 - 0.022 14.2 0.0 0.049 13.1 0.0 1.6 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 EIE83615.1 - 0.061 13.3 0.0 0.16 12.0 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.7 EIE83615.1 - 0.068 12.6 0.0 0.78 9.2 0.0 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF938) PrmA PF06325.8 EIE83615.1 - 0.074 12.1 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) rve_3 PF13683.1 EIE83615.1 - 0.57 9.7 3.2 1.3 8.5 1.9 1.8 2 0 0 2 2 2 0 Integrase core domain Prp18 PF02840.10 EIE83616.1 - 8.8e-57 191.0 0.1 8.8e-57 191.0 0.1 1.3 2 0 0 2 2 2 1 Prp18 domain FA_desaturase PF00487.19 EIE83618.1 - 8.3e-47 159.7 10.1 1.6e-46 158.8 5.9 1.9 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.23 EIE83618.1 - 5.2e-19 67.8 0.1 1.5e-18 66.3 0.1 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Ras PF00071.17 EIE83619.1 - 4.6e-52 175.6 0.1 5.8e-52 175.3 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIE83619.1 - 1.1e-17 64.6 0.1 1.6e-17 64.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIE83619.1 - 2.6e-08 33.3 0.0 3.4e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EIE83619.1 - 0.0029 17.5 0.4 0.0059 16.5 0.1 1.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EIE83619.1 - 0.0032 17.5 0.2 0.059 13.5 0.1 2.5 2 1 0 2 2 2 1 AAA domain PduV-EutP PF10662.4 EIE83619.1 - 0.011 15.2 0.1 0.044 13.2 0.0 2.0 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_15 PF13175.1 EIE83619.1 - 0.013 14.5 0.2 0.015 14.3 0.1 1.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.1 EIE83619.1 - 0.017 15.0 0.1 0.045 13.6 0.1 1.7 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 EIE83619.1 - 0.027 13.6 0.1 0.04 13.1 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_24 PF13479.1 EIE83619.1 - 0.035 13.6 0.1 0.076 12.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.13 EIE83619.1 - 0.071 12.3 0.2 0.37 10.0 0.1 1.9 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_16 PF13191.1 EIE83619.1 - 0.11 12.4 0.2 0.32 10.9 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain Crp PF00325.15 EIE83619.1 - 0.14 11.6 0.0 0.32 10.4 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family ABC_tran PF00005.22 EIE83619.1 - 0.14 12.4 0.3 0.23 11.7 0.2 1.6 1 1 0 1 1 1 0 ABC transporter NACHT PF05729.7 EIE83619.1 - 0.15 11.7 0.0 0.43 10.2 0.0 1.7 2 0 0 2 2 2 0 NACHT domain AAA_21 PF13304.1 EIE83619.1 - 0.38 10.6 3.9 0.87 9.4 2.2 2.0 1 1 1 2 2 2 0 AAA domain CLTH PF10607.4 EIE83620.1 - 7.1e-26 90.6 6.0 1e-25 90.1 4.1 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 EIE83620.1 - 3.9e-05 23.2 0.0 9.3e-05 22.0 0.0 1.6 1 0 0 1 1 1 1 LisH TINF2_N PF14973.1 EIE83620.1 - 7.4e-05 22.9 2.9 0.00023 21.3 1.4 2.0 2 0 0 2 2 2 1 TERF1-interacting nuclear factor 2 N-terminus Ribosomal_L38e PF01781.13 EIE83621.1 - 7.5e-35 118.5 4.7 8.2e-35 118.3 3.3 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family TFIID_90kDa PF04494.10 EIE83621.1 - 0.02 14.9 0.1 0.021 14.8 0.1 1.1 1 0 0 1 1 1 0 WD40 associated region in TFIID subunit EMA PF02488.10 EIE83621.1 - 0.11 12.0 0.8 0.12 11.8 0.6 1.0 1 0 0 1 1 1 0 Merozoite Antigen Fumarate_red_C PF02300.12 EIE83622.1 - 0.076 12.8 0.0 0.088 12.6 0.0 1.0 1 0 0 1 1 1 0 Fumarate reductase subunit C DUF1352 PF07086.7 EIE83624.1 - 0.023 14.3 0.7 0.9 9.1 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1352) PH PF00169.24 EIE83625.1 - 5.2e-20 71.5 1.5 5.2e-20 71.5 1.1 2.9 4 0 0 4 4 4 1 PH domain SH3_9 PF14604.1 EIE83625.1 - 8.2e-14 50.9 0.1 1.8e-13 49.8 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SAM_2 PF07647.12 EIE83625.1 - 9.8e-14 50.9 0.0 4.2e-13 48.9 0.0 2.1 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SH3_1 PF00018.23 EIE83625.1 - 1.6e-13 49.7 0.5 1.6e-13 49.7 0.3 2.3 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 EIE83625.1 - 1.5e-09 37.2 0.1 3e-09 36.2 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SAM_1 PF00536.25 EIE83625.1 - 1.5e-08 34.6 0.0 5.4e-08 32.8 0.0 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) PH_11 PF15413.1 EIE83625.1 - 1.8e-06 28.1 5.6 4.2e-05 23.7 3.9 2.7 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 EIE83625.1 - 0.0026 17.8 2.7 0.0064 16.5 1.0 2.5 2 1 0 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.1 EIE83625.1 - 0.0028 17.5 0.7 0.0064 16.3 0.5 1.5 1 0 0 1 1 1 1 PH domain Ste50p-SAM PF09235.5 EIE83625.1 - 0.0029 17.5 1.3 0.17 11.8 0.1 2.7 2 0 0 2 2 2 1 Ste50p, sterile alpha motif Thaumatin PF00314.12 EIE83626.1 - 2.4e-50 170.9 15.9 2.8e-49 167.4 11.0 2.0 1 1 0 1 1 1 1 Thaumatin family T4-Gluco-transf PF09198.5 EIE83627.1 - 0.043 13.1 0.1 0.064 12.5 0.1 1.3 1 0 0 1 1 1 0 Bacteriophage T4 beta-glucosyltransferase EST1 PF10374.4 EIE83628.1 - 0.095 12.6 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Telomerase activating protein Est1 Metallothio_2 PF01439.13 EIE83631.1 - 0.21 12.1 11.7 0.19 12.2 2.8 2.7 2 0 0 2 2 2 0 Metallothionein UCH PF00443.24 EIE83632.1 - 2.8e-43 147.9 3.4 4.3e-43 147.3 2.4 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EIE83632.1 - 1.9e-12 47.2 8.4 2.8e-12 46.6 5.8 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Glyco_hydro_28 PF00295.12 EIE83633.1 - 1.1e-70 238.2 24.1 1.3e-70 237.9 16.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 End_N_terminal PF12218.3 EIE83633.1 - 0.29 10.6 1.6 4.2 6.9 0.0 3.0 3 1 0 3 3 3 0 N terminal extension of bacteriophage endosialidase CPSase_L_D2 PF02786.12 EIE83634.1 - 2.1e-64 216.6 0.0 4.2e-64 215.7 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 EIE83634.1 - 4.5e-29 100.5 0.0 1.4e-28 98.9 0.0 1.9 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 EIE83634.1 - 1.5e-28 99.0 0.3 3.8e-28 97.8 0.2 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 EIE83634.1 - 7.7e-19 68.1 0.0 1.6e-18 67.1 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 EIE83634.1 - 2.3e-15 55.9 3.4 4.7e-15 54.9 1.1 2.4 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.8 EIE83634.1 - 3.7e-12 46.0 0.0 1.6e-11 44.0 0.0 2.0 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.1 EIE83634.1 - 8.5e-10 38.1 0.7 3.2e-06 26.6 0.0 2.9 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp_3 PF02655.9 EIE83634.1 - 9.5e-09 35.3 0.0 2.9e-08 33.7 0.0 1.9 2 0 0 2 2 1 1 ATP-grasp domain ATP-grasp PF02222.17 EIE83634.1 - 2e-08 33.7 0.0 4.2e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EIE83634.1 - 1.8e-07 30.2 0.8 0.0092 14.7 0.0 2.9 3 0 0 3 3 3 2 ATP-grasp in the biosynthetic pathway with Ter operon HlyD PF00529.15 EIE83634.1 - 4.4e-07 29.5 0.9 0.00011 21.6 0.1 2.5 1 1 1 2 2 2 2 HlyD family secretion protein HlyD_3 PF13437.1 EIE83634.1 - 3.1e-05 24.2 0.9 0.16 12.3 0.0 3.8 3 0 0 3 3 3 2 HlyD family secretion protein NQRA PF05896.6 EIE83634.1 - 0.0001 21.6 0.2 0.00024 20.3 0.1 1.6 1 0 0 1 1 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) RnfC_N PF13375.1 EIE83634.1 - 0.00035 20.2 1.4 0.0055 16.3 0.1 2.6 2 0 0 2 2 2 1 RnfC Barrel sandwich hybrid domain HlyD_2 PF12700.2 EIE83634.1 - 0.0018 17.4 3.8 0.0035 16.5 0.1 2.6 2 1 1 3 3 3 1 HlyD family secretion protein DUF2118 PF09891.4 EIE83634.1 - 0.006 16.2 0.0 0.015 14.9 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2118) GCV_H PF01597.14 EIE83634.1 - 0.012 15.3 0.1 0.032 13.9 0.1 1.7 1 0 0 1 1 1 0 Glycine cleavage H-protein PsbY PF06298.6 EIE83635.1 - 0.17 11.4 0.5 0.26 10.8 0.3 1.3 1 0 0 1 1 1 0 Photosystem II protein Y (PsbY) SRP19 PF01922.12 EIE83637.1 - 2.3e-24 85.8 0.4 5.7e-24 84.5 0.1 1.8 2 0 0 2 2 2 1 SRP19 protein MAT1 PF06391.8 EIE83638.1 - 2.2e-22 79.6 13.9 3e-22 79.2 9.7 1.2 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 V_ATPase_I PF01496.14 EIE83638.1 - 0.02 12.7 4.7 0.019 12.8 3.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MRP-S26 PF14943.1 EIE83638.1 - 0.13 11.7 14.9 0.23 11.0 10.3 1.5 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 Med4 PF10018.4 EIE83638.1 - 0.34 10.2 13.5 0.18 11.1 8.1 1.5 1 1 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Mnd1 PF03962.10 EIE83638.1 - 0.41 10.2 14.0 0.59 9.7 9.7 1.2 1 0 0 1 1 1 0 Mnd1 family PSI_PsaF PF02507.10 EIE83638.1 - 0.53 9.8 2.8 0.49 9.9 0.2 2.0 1 1 0 2 2 2 0 Photosystem I reaction centre subunit III APG6 PF04111.7 EIE83638.1 - 0.74 8.8 14.2 1 8.3 9.9 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 LMBR1 PF04791.11 EIE83638.1 - 4.1 5.8 5.5 4.9 5.6 3.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4140 PF13600.1 EIE83638.1 - 9.8 6.6 13.3 6.7 7.2 7.2 2.3 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Gpi1 PF05024.10 EIE83640.1 - 3.8e-42 144.1 11.6 5.1e-23 81.7 0.9 2.5 1 1 1 2 2 2 2 N-acetylglucosaminyl transferase component (Gpi1) Corona_S2 PF01601.11 EIE83641.1 - 0.0026 15.9 2.7 0.0034 15.5 1.9 1.2 1 0 0 1 1 1 1 Coronavirus S2 glycoprotein PhageMin_Tail PF10145.4 EIE83641.1 - 0.0051 16.4 0.3 0.0051 16.4 0.2 2.1 2 1 0 2 2 2 1 Phage-related minor tail protein BLOC1_2 PF10046.4 EIE83641.1 - 0.0077 16.3 5.5 0.0077 16.3 3.8 2.9 2 1 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Baculo_PEP_C PF04513.7 EIE83641.1 - 0.0098 15.7 2.0 0.0098 15.7 1.4 1.9 1 1 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.7 EIE83641.1 - 0.014 15.2 7.8 0.014 15.2 5.4 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Psb28 PF03912.9 EIE83641.1 - 0.015 15.2 0.5 0.053 13.4 0.4 1.9 1 0 0 1 1 1 0 Psb28 protein Reo_sigmaC PF04582.7 EIE83641.1 - 0.31 10.1 6.4 0.26 10.4 2.7 1.7 1 1 1 2 2 2 0 Reovirus sigma C capsid protein IncA PF04156.9 EIE83641.1 - 0.62 9.6 32.4 2.7 7.5 19.0 2.4 1 1 1 2 2 2 0 IncA protein DUF948 PF06103.6 EIE83641.1 - 2 8.3 6.7 2.6 7.9 1.5 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF3584 PF12128.3 EIE83641.1 - 2.2 5.5 28.2 0.2 8.9 8.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Laminin_II PF06009.7 EIE83641.1 - 2.8 7.6 19.8 0.16 11.7 5.5 3.0 1 1 2 3 3 3 0 Laminin Domain II FlaC_arch PF05377.6 EIE83641.1 - 5.4 7.0 18.2 2.7 7.9 5.7 4.0 2 2 2 4 4 4 0 Flagella accessory protein C (FlaC) Flagellin_N PF00669.15 EIE83641.1 - 5.4 6.8 11.5 0.33 10.7 1.2 2.9 2 1 0 2 2 2 0 Bacterial flagellin N-terminal helical region KxDL PF10241.4 EIE83641.1 - 8.2 6.4 16.6 1.1 9.2 2.2 4.1 1 1 2 4 4 4 0 Uncharacterized conserved protein Fcf2 PF08698.6 EIE83642.1 - 7.2e-37 125.3 2.4 7.2e-37 125.3 1.7 1.9 1 1 1 2 2 2 1 Fcf2 pre-rRNA processing DUF4337 PF14235.1 EIE83642.1 - 6.4 6.5 7.4 19 5.0 1.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) Myb_DNA-bind_6 PF13921.1 EIE83643.1 - 4.4e-06 26.7 0.0 7.5e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EIE83643.1 - 0.0037 17.2 0.0 0.0061 16.5 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain GPI-anchored PF10342.4 EIE83644.1 - 1.8e-06 28.3 0.5 1.8e-06 28.3 0.4 1.8 1 1 1 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family p450 PF00067.17 EIE83646.1 - 1.1e-45 155.9 0.0 1.2e-45 155.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RVT_1 PF00078.22 EIE83648.1 - 4.4e-26 91.5 0.0 9.3e-26 90.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.1 EIE83648.1 - 1.2e-06 28.7 1.6 3.5e-06 27.2 1.1 1.8 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Auxin_resp PF06507.8 EIE83649.1 - 0.079 12.8 0.1 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Auxin response factor ADH_zinc_N PF00107.21 EIE83651.1 - 5.3e-26 90.6 0.5 8.2e-26 90.0 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIE83651.1 - 7.3e-10 38.5 0.0 1.4e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EIE83651.1 - 0.0013 19.5 0.2 0.0065 17.3 0.1 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 EIE83651.1 - 0.0016 18.4 0.3 0.002 18.1 0.2 1.2 1 0 0 1 1 1 1 NADH(P)-binding TrkA_N PF02254.13 EIE83651.1 - 0.0017 18.3 0.1 0.0028 17.6 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain AlaDh_PNT_C PF01262.16 EIE83651.1 - 0.0086 15.6 0.1 0.012 15.1 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain SIS_2 PF13580.1 EIE83651.1 - 0.11 12.2 0.1 0.16 11.7 0.1 1.3 1 0 0 1 1 1 0 SIS domain Ribosomal_L24e PF01246.15 EIE83652.1 - 1.1e-21 76.4 1.2 1.1e-21 76.4 0.8 2.2 2 2 1 3 3 3 1 Ribosomal protein L24e W2 PF02020.13 EIE83653.1 - 5.4e-11 42.2 6.2 5.4e-11 42.2 4.3 3.3 3 1 0 3 3 2 1 eIF4-gamma/eIF5/eIF2-epsilon Radial_spoke PF04712.7 EIE83653.1 - 0.013 14.3 11.4 0.14 10.9 2.1 2.3 2 0 0 2 2 2 0 Radial spokehead-like protein bZIP_1 PF00170.16 EIE83653.1 - 0.037 13.9 7.2 0.17 11.8 0.5 2.6 2 0 0 2 2 2 0 bZIP transcription factor Glutaredoxin2_C PF04399.8 EIE83653.1 - 0.049 13.2 1.9 0.65 9.5 0.1 2.5 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain DUF342 PF03961.8 EIE83653.1 - 0.21 9.9 4.4 0.48 8.7 3.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Phage_Nu1 PF07471.7 EIE83653.1 - 0.21 11.0 4.8 0.12 11.7 0.6 2.4 2 0 0 2 2 2 0 Phage DNA packaging protein Nu1 CENP-L PF13092.1 EIE83653.1 - 0.41 10.4 5.1 1 9.1 0.1 2.9 2 2 0 3 3 3 0 Kinetochore complex Sim4 subunit Fta1 bZIP_2 PF07716.10 EIE83653.1 - 0.54 10.1 10.2 3.3 7.6 2.5 2.9 2 0 0 2 2 2 0 Basic region leucine zipper CENP-B_dimeris PF09026.5 EIE83653.1 - 2.9 8.1 23.3 4.1 7.6 7.6 2.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain SDA1 PF05285.7 EIE83653.1 - 3.1 7.0 27.3 0.41 9.8 6.2 2.2 2 0 0 2 2 2 0 SDA1 DUF4637 PF15470.1 EIE83653.1 - 6.1 6.4 16.2 8.5 5.9 1.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) DUF1676 PF07898.8 EIE83653.1 - 7.8 6.8 11.7 13 6.1 1.6 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1676) NDT80_PhoG PF05224.7 EIE83654.1 - 3.1e-36 125.1 0.2 2.3e-35 122.3 0.0 2.5 2 1 0 2 2 2 1 NDT80 / PhoG like DNA-binding family ELFV_dehydrog PF00208.16 EIE83655.1 - 1.2e-49 169.0 0.0 2.4e-49 168.1 0.0 1.5 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 EIE83655.1 - 4.2e-27 94.1 0.1 2.4e-20 71.7 0.0 2.6 3 0 0 3 3 3 2 Bacterial NAD-glutamate dehydrogenase DUF1858 PF08984.6 EIE83655.1 - 0.13 11.9 0.1 0.34 10.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1858) Vps5 PF09325.5 EIE83656.1 - 4.6e-06 26.0 5.5 4.6e-06 26.0 3.8 1.6 2 0 0 2 2 2 1 Vps5 C terminal like Syntaphilin PF15290.1 EIE83656.1 - 0.079 12.4 10.6 0.11 11.9 7.4 1.2 1 0 0 1 1 1 0 Golgi-localised syntaxin-1-binding clamp MRC1 PF09444.5 EIE83657.1 - 3.2 8.0 8.9 2.2 8.5 4.4 2.0 1 1 0 1 1 1 0 MRC1-like domain Ribosomal_S26e PF01283.14 EIE83658.1 - 5.2e-52 174.9 9.0 5.7e-52 174.7 6.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Fer4_10 PF13237.1 EIE83658.1 - 0.25 11.1 3.9 0.77 9.6 1.0 2.0 1 1 1 2 2 2 0 4Fe-4S dicluster domain Zn_ribbon_2 PF12674.2 EIE83658.1 - 0.25 11.6 2.1 1.3 9.3 0.1 2.1 1 1 1 2 2 2 0 Putative zinc ribbon domain Fer4_2 PF12797.2 EIE83658.1 - 0.39 10.7 3.3 0.75 9.8 0.6 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_7 PF12838.2 EIE83658.1 - 0.41 11.0 3.7 3.5 8.0 1.2 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_8 PF13183.1 EIE83658.1 - 0.72 9.9 3.8 1.9 8.5 2.5 1.8 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4 PF00037.22 EIE83658.1 - 1.2 8.8 4.7 0.79 9.4 0.7 2.1 2 0 0 2 2 2 0 4Fe-4S binding domain Mmp37 PF09139.6 EIE83659.1 - 8.3e-105 350.4 0.3 9.4e-105 350.2 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial matrix Mmp37 Minor_tail_Z PF06763.6 EIE83659.1 - 0.11 12.1 0.1 9.3 5.8 0.0 2.2 2 0 0 2 2 2 0 Prophage minor tail protein Z (GPZ) RRM_5 PF13893.1 EIE83660.1 - 1.4e-08 34.4 0.0 0.00014 21.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE83660.1 - 2.4e-07 30.6 0.0 5e-05 23.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EIE83660.1 - 9.5e-05 21.9 0.0 0.079 12.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ILVD_EDD PF00920.16 EIE83661.1 - 8.1e-211 700.9 4.3 9.2e-211 700.7 3.0 1.0 1 0 0 1 1 1 1 Dehydratase family HATPase_c PF02518.21 EIE83662.1 - 7.9e-30 102.8 0.0 3.7e-29 100.6 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EIE83662.1 - 1.2e-24 86.5 0.3 6.6e-22 77.6 0.0 3.5 3 0 0 3 3 3 1 Response regulator receiver domain HisKA PF00512.20 EIE83662.1 - 5.1e-18 64.8 0.0 2.4e-17 62.6 0.0 2.3 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Pkinase PF00069.20 EIE83662.1 - 8.1e-17 61.2 0.0 1.8e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE83662.1 - 4.5e-09 35.7 0.0 1.2e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase GAF_2 PF13185.1 EIE83662.1 - 2.1e-08 34.7 0.0 4.8e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 GAF domain AAA_16 PF13191.1 EIE83662.1 - 7.8e-08 32.5 0.0 2.8e-07 30.6 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain GAF_3 PF13492.1 EIE83662.1 - 6.1e-07 29.5 0.0 1.3e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 GAF domain GAF PF01590.21 EIE83662.1 - 6.4e-06 26.3 0.0 1.3e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 GAF domain AAA_22 PF13401.1 EIE83662.1 - 1.6e-05 25.0 0.0 0.0072 16.4 0.0 3.7 3 0 0 3 3 3 1 AAA domain NB-ARC PF00931.17 EIE83662.1 - 4.1e-05 22.5 0.2 0.055 12.3 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain Kinase-like PF14531.1 EIE83662.1 - 0.0002 20.4 0.1 0.00063 18.7 0.0 1.8 2 0 0 2 2 2 1 Kinase-like ABC_tran PF00005.22 EIE83662.1 - 0.0045 17.2 0.0 0.018 15.3 0.0 2.1 1 0 0 1 1 1 1 ABC transporter AAA_17 PF13207.1 EIE83662.1 - 0.02 15.6 3.9 0.041 14.7 0.0 3.5 3 1 0 3 3 2 0 AAA domain MobB PF03205.9 EIE83662.1 - 0.03 14.0 0.0 0.3 10.7 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 EIE83662.1 - 0.033 13.3 0.0 0.079 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 CbiA PF01656.18 EIE83662.1 - 0.037 13.4 0.0 2.5 7.4 0.0 2.6 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_29 PF13555.1 EIE83662.1 - 0.051 13.1 0.0 0.14 11.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain HATPase_c_3 PF13589.1 EIE83662.1 - 0.056 13.0 0.1 0.29 10.7 0.0 2.2 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AAA_23 PF13476.1 EIE83662.1 - 0.33 11.2 7.1 0.45 10.7 0.0 3.7 4 0 0 4 4 3 0 AAA domain OrfB_Zn_ribbon PF07282.6 EIE83664.1 - 0.0053 16.3 0.3 0.027 14.1 0.0 2.3 2 0 0 2 2 2 1 Putative transposase DNA-binding domain Peptidase_C12 PF01088.16 EIE83666.1 - 3.6e-40 137.4 0.0 7.1e-40 136.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Sulfate_transp PF00916.15 EIE83667.1 - 3.9e-08 32.6 13.4 3.9e-08 32.6 9.3 2.0 2 1 0 2 2 2 1 Sulfate transporter family DUF4131 PF13567.1 EIE83667.1 - 4 6.8 9.8 0.15 11.4 0.7 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) Sec2p PF06428.6 EIE83668.1 - 7.6e-15 54.6 14.9 7.6e-15 54.6 10.4 2.4 1 1 1 2 2 2 1 GDP/GTP exchange factor Sec2p IncA PF04156.9 EIE83668.1 - 0.01 15.4 16.9 0.01 15.4 11.7 2.3 1 1 1 2 2 2 0 IncA protein AAA_13 PF13166.1 EIE83668.1 - 0.013 14.0 22.7 0.019 13.4 15.1 1.7 1 1 0 1 1 1 0 AAA domain Myosin_tail_1 PF01576.14 EIE83668.1 - 0.018 12.8 31.4 0.029 12.1 21.7 1.2 1 0 0 1 1 1 0 Myosin tail DUF3773 PF12608.3 EIE83668.1 - 0.061 13.3 0.0 0.33 11.0 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3773) FAM101 PF15068.1 EIE83668.1 - 0.11 11.8 0.9 0.26 10.7 0.6 1.6 1 0 0 1 1 1 0 FAM101 family Matrilin_ccoil PF10393.4 EIE83668.1 - 0.12 11.7 8.2 0.56 9.6 0.3 4.2 3 1 1 4 4 4 0 Trimeric coiled-coil oligomerisation domain of matrilin Reo_sigmaC PF04582.7 EIE83668.1 - 0.22 10.6 2.6 0.47 9.5 1.8 1.5 1 1 0 1 1 1 0 Reovirus sigma C capsid protein Tropomyosin PF00261.15 EIE83668.1 - 0.72 8.9 31.9 0.27 10.3 15.4 2.2 1 1 2 3 3 3 0 Tropomyosin DUF883 PF05957.8 EIE83668.1 - 0.82 10.1 11.0 0.57 10.6 3.0 2.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Filament PF00038.16 EIE83668.1 - 0.92 8.9 29.0 0.25 10.7 9.1 2.2 1 1 0 2 2 2 0 Intermediate filament protein Fez1 PF06818.10 EIE83668.1 - 1.6 8.7 22.9 2.8 7.8 15.9 1.4 1 0 0 1 1 1 0 Fez1 DUF1664 PF07889.7 EIE83668.1 - 2.2 8.0 15.5 1.7 8.4 3.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Atg14 PF10186.4 EIE83668.1 - 2.3 7.0 22.5 2.4 7.0 7.0 2.2 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Tho2 PF11262.3 EIE83668.1 - 2.6 7.0 20.0 1.2 8.1 3.1 2.5 1 1 2 3 3 3 0 Transcription factor/nuclear export subunit protein 2 DUF4407 PF14362.1 EIE83668.1 - 5.3 5.9 14.5 12 4.6 10.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) ATG16 PF08614.6 EIE83668.1 - 6.7 6.4 29.3 1.4 8.7 9.9 2.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) GAGA_bind PF06217.7 EIE83668.1 - 6.8 6.5 9.8 10 5.9 6.8 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Spc7 PF08317.6 EIE83668.1 - 7.4 5.1 27.8 1.1 7.9 6.1 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF3552 PF12072.3 EIE83668.1 - 7.5 5.7 34.1 2.7 7.1 13.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) DUF2570 PF10828.3 EIE83668.1 - 9.3 5.9 15.9 0.36 10.4 1.7 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2570) CBFD_NFYB_HMF PF00808.18 EIE83669.1 - 2e-18 66.1 1.0 2e-18 66.1 0.7 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone IMPDH PF00478.20 EIE83669.1 - 0.056 12.3 0.1 0.064 12.1 0.1 1.1 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain Histone PF00125.19 EIE83669.1 - 0.072 13.2 0.2 0.15 12.1 0.1 1.7 1 1 0 1 1 1 0 Core histone H2A/H2B/H3/H4 G-patch PF01585.18 EIE83670.1 - 3.6e-12 45.8 1.4 8.2e-12 44.7 1.0 1.7 1 0 0 1 1 1 1 G-patch domain RRM_5 PF13893.1 EIE83670.1 - 1.7e-10 40.5 0.1 5.5e-10 38.9 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EIE83670.1 - 5.9e-07 29.0 0.0 1.4e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE83670.1 - 4.1e-05 23.4 0.0 0.00012 22.0 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Whirly PF08536.6 EIE83670.1 - 0.02 14.3 0.5 0.44 10.0 0.0 2.3 2 0 0 2 2 2 0 Whirly transcription factor G-patch_2 PF12656.2 EIE83670.1 - 0.49 10.2 0.0 0.49 10.2 0.0 2.7 3 0 0 3 3 3 0 DExH-box splicing factor binding site APC_CDC26 PF10471.4 EIE83670.1 - 6.2 7.6 17.0 0.87 10.3 2.5 4.0 4 0 0 4 4 4 0 Anaphase-promoting complex APC subunit 1 PAP_assoc PF03828.14 EIE83671.1 - 2e-07 30.8 0.1 3e-07 30.2 0.1 1.3 1 0 0 1 1 1 1 Cid1 family poly A polymerase Methyltransf_18 PF12847.2 EIE83672.1 - 7e-08 33.0 0.0 1.8e-07 31.6 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIE83672.1 - 1.2e-06 28.5 0.0 0.0003 20.8 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EIE83672.1 - 4.5e-06 26.1 0.0 2e-05 24.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain PrmA PF06325.8 EIE83672.1 - 7.6e-06 25.2 0.1 1.2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.10 EIE83672.1 - 4.3e-05 22.9 0.0 0.063 12.6 0.0 2.2 2 0 0 2 2 2 2 Conserved hypothetical protein 95 Methyltransf_23 PF13489.1 EIE83672.1 - 6.3e-05 22.7 0.0 0.00012 21.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIE83672.1 - 0.00034 20.2 0.0 0.00066 19.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 EIE83672.1 - 0.00079 18.4 0.0 0.021 13.7 0.0 2.0 1 1 1 2 2 2 1 PRMT5 arginine-N-methyltransferase DREV PF05219.7 EIE83672.1 - 0.0059 15.5 0.0 0.013 14.3 0.0 1.5 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_11 PF08241.7 EIE83672.1 - 0.015 15.7 0.0 0.045 14.2 0.0 1.8 2 0 0 2 2 1 0 Methyltransferase domain Methyltransf_9 PF08003.6 EIE83672.1 - 0.025 13.2 0.0 0.039 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Rsm22 PF09243.5 EIE83672.1 - 0.027 13.4 0.0 0.058 12.4 0.0 1.5 2 0 0 2 2 2 0 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_16 PF10294.4 EIE83672.1 - 0.035 13.5 0.0 0.054 12.9 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_25 PF13649.1 EIE83672.1 - 0.077 13.3 0.0 0.18 12.1 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.20 EIE83673.1 - 5e-54 183.1 0.1 1.2e-53 181.9 0.1 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE83673.1 - 3.2e-24 85.3 0.0 8.8e-24 83.9 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE83673.1 - 3.9e-05 22.7 0.0 0.00051 19.0 0.0 2.4 1 1 1 2 2 2 1 Kinase-like Pox_ser-thr_kin PF05445.6 EIE83673.1 - 0.007 15.2 0.1 0.013 14.3 0.0 1.3 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase MSV199 PF10553.4 EIE83673.1 - 0.036 13.9 0.1 0.036 13.9 0.1 2.9 2 1 0 2 2 2 0 MSV199 domain DUF4442 PF14539.1 EIE83674.1 - 6.4e-19 68.2 0.0 8.6e-19 67.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) 4HBT PF03061.17 EIE83674.1 - 0.022 14.8 0.0 0.044 13.9 0.0 1.5 1 0 0 1 1 1 0 Thioesterase superfamily Ribosomal_L34e PF01199.13 EIE83675.1 - 7.6e-41 138.2 6.0 9.2e-41 137.9 4.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L34e GFA PF04828.9 EIE83675.1 - 0.093 12.6 0.7 0.33 10.9 0.0 1.9 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme RRM_1 PF00076.17 EIE83677.1 - 1.1e-23 82.6 0.1 2.8e-23 81.3 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE83677.1 - 5.3e-14 51.9 0.0 1.2e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE83677.1 - 8.7e-06 25.4 0.0 1.7e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 EIE83677.1 - 2.2e-05 23.9 1.7 0.013 15.1 0.0 2.8 3 0 0 3 3 3 2 Poly-adenylate binding protein, unique domain YlbD_coat PF14071.1 EIE83677.1 - 0.11 12.5 1.5 0.2 11.7 0.2 2.1 2 0 0 2 2 2 0 Putative coat protein RRM_1 PF00076.17 EIE83678.1 - 6e-16 57.8 0.0 9e-16 57.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE83678.1 - 4.1e-09 36.3 0.0 6.7e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE83678.1 - 1.5e-08 34.3 0.6 3.5e-08 33.1 0.0 2.0 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.18 EIE83678.1 - 0.13 12.2 1.6 0.27 11.2 1.1 1.6 1 0 0 1 1 1 0 Zinc knuckle PRP38_assoc PF12871.2 EIE83678.1 - 8.3 7.0 32.0 5 7.7 13.3 2.4 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Glucosamine_iso PF01182.15 EIE83679.1 - 0.046 13.4 0.0 0.052 13.2 0.0 1.0 1 0 0 1 1 1 0 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase HECT PF00632.20 EIE83680.1 - 0.00033 19.9 0.0 0.64 9.1 0.0 3.3 1 1 1 2 2 2 2 HECT-domain (ubiquitin-transferase) RNase_P_p30 PF01876.11 EIE83680.1 - 0.0057 15.9 4.3 0.16 11.2 0.3 3.0 1 1 3 4 4 4 2 RNase P subunit p30 DUF1836 PF08876.6 EIE83680.1 - 0.027 14.2 1.6 0.64 9.8 0.5 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF1836) TMEM89 PF15098.1 EIE83680.1 - 0.1 12.5 0.1 11 6.0 0.0 2.3 1 1 0 2 2 2 0 TMEM89 protein family Pkinase PF00069.20 EIE83683.1 - 9.4e-62 208.4 0.3 4e-61 206.4 0.2 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE83683.1 - 1.7e-24 86.2 0.0 6.2e-24 84.4 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase PACT_coil_coil PF10495.4 EIE83683.1 - 0.11 12.4 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein DUF973 PF06157.6 EIE83685.1 - 0.045 12.7 0.8 0.053 12.4 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF973) Clat_adaptor_s PF01217.15 EIE83685.1 - 0.28 10.8 3.7 0.31 10.7 0.5 1.9 1 1 1 2 2 2 0 Clathrin adaptor complex small chain Exo_endo_phos PF03372.18 EIE83686.1 - 1.6e-15 57.6 0.0 2.8e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 EIE83686.1 - 0.00014 21.3 0.1 0.00033 20.1 0.1 1.6 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EIE83686.1 - 0.068 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Leucine rich repeat CCDC32 PF14989.1 EIE83689.1 - 0.0018 18.0 0.4 0.0025 17.6 0.3 1.3 1 1 0 1 1 1 1 Coiled-coil domain containing 32 PAP_central PF04928.12 EIE83689.1 - 0.059 12.1 0.1 0.07 11.9 0.0 1.1 1 0 0 1 1 1 0 Poly(A) polymerase central domain Sec6 PF06046.8 EIE83691.1 - 2.3e-91 306.6 5.2 5.5e-91 305.3 3.6 1.6 1 1 0 1 1 1 1 Exocyst complex component Sec6 Baculo_PEP_C PF04513.7 EIE83691.1 - 0.32 10.7 2.9 0.49 10.2 0.4 2.5 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Vps53_N PF04100.7 EIE83691.1 - 0.6 8.8 7.6 0.11 11.2 0.5 2.3 2 0 0 2 2 2 0 Vps53-like, N-terminal WD40 PF00400.27 EIE83692.1 - 4.4e-19 67.5 5.1 0.00031 20.5 0.0 5.4 5 0 0 5 5 5 5 WD domain, G-beta repeat BBS2_Mid PF14783.1 EIE83692.1 - 0.0018 18.0 0.2 0.0076 16.0 0.0 2.1 2 1 1 3 3 3 1 Ciliary BBSome complex subunit 2, middle region eIF2A PF08662.6 EIE83692.1 - 0.011 15.4 0.1 0.043 13.5 0.0 2.1 1 1 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A PCI PF01399.22 EIE83693.1 - 2.4e-24 85.6 3.2 5.1e-24 84.6 0.6 2.5 2 0 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 EIE83693.1 - 6.2e-15 55.2 0.6 6.2e-15 55.2 0.4 2.0 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 EIE83693.1 - 0.056 13.0 6.9 0.037 13.5 2.5 2.3 1 1 0 1 1 1 0 SAC3/GANP/Nin1/mts3/eIF-3 p25 family AAL_decarboxy PF03306.8 EIE83693.1 - 0.075 12.0 0.1 0.51 9.3 0.0 2.1 2 0 0 2 2 2 0 Alpha-acetolactate decarboxylase LRR_6 PF13516.1 EIE83696.1 - 1.4e-05 24.6 0.2 4.9 7.5 0.0 3.5 3 0 0 3 3 3 3 Leucine Rich repeat LRR_1 PF00560.28 EIE83696.1 - 4.6e-05 22.8 0.1 6 7.3 0.0 3.7 3 0 0 3 3 3 3 Leucine Rich Repeat LRR_4 PF12799.2 EIE83696.1 - 0.0015 18.0 3.6 0.39 10.4 0.2 3.1 2 2 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EIE83696.1 - 0.016 15.3 1.4 56 4.6 0.0 4.0 4 0 0 4 4 4 0 Leucine rich repeat Pkinase PF00069.20 EIE83697.1 - 6.3e-68 228.7 0.0 9.8e-68 228.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE83697.1 - 6.7e-47 159.7 0.0 1.1e-46 159.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 EIE83697.1 - 8.8e-22 77.2 0.1 3.1e-21 75.5 0.1 2.0 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.1 EIE83697.1 - 4.8e-07 29.0 0.0 7.6e-07 28.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EIE83697.1 - 0.019 14.7 2.0 0.13 11.9 0.1 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family Glyco_hydro_9 PF00759.14 EIE83700.1 - 7.5e-32 110.7 1.5 9.1e-32 110.5 1.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Acyl-CoA_dh_1 PF00441.19 EIE83701.1 - 1.1e-33 116.4 1.9 1.8e-33 115.7 1.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EIE83701.1 - 3.9e-17 61.5 0.0 8.2e-17 60.4 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EIE83701.1 - 1.7e-15 57.4 3.3 3.1e-15 56.6 2.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EIE83701.1 - 1.2e-10 41.9 0.0 0.00015 22.2 0.0 2.6 1 1 1 2 2 2 2 Acyl-CoA dehydrogenase, N-terminal domain Sec8_exocyst PF04048.9 EIE83701.1 - 0.013 15.0 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain HpaB_N PF11794.3 EIE83701.1 - 0.076 12.3 0.0 0.17 11.2 0.0 1.6 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal DUF500 PF04366.7 EIE83702.1 - 8.1e-28 96.3 0.0 1.4e-27 95.6 0.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF500) SH3_1 PF00018.23 EIE83702.1 - 1.4e-17 62.8 0.2 2.9e-17 61.7 0.0 1.7 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EIE83702.1 - 3.1e-17 61.8 0.1 5.9e-17 60.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EIE83702.1 - 1.1e-12 47.2 0.0 2.2e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain zf-C3HC4_2 PF13923.1 EIE83703.1 - 2.1e-09 37.2 10.5 3.8e-09 36.4 7.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIE83703.1 - 5.2e-08 32.5 9.8 9.8e-08 31.7 6.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EIE83703.1 - 6.8e-08 32.0 9.2 1.3e-07 31.1 6.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EIE83703.1 - 1.2e-06 28.0 5.6 2.1e-06 27.2 3.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIE83703.1 - 1.2e-05 24.9 6.8 2.3e-05 24.0 4.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EIE83703.1 - 8.9e-05 22.2 6.3 0.00026 20.8 4.4 1.8 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EIE83703.1 - 0.0002 21.0 4.0 0.0021 17.7 2.9 2.5 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.2 EIE83703.1 - 0.0019 18.2 5.3 0.0041 17.1 3.7 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger FYVE PF01363.16 EIE83703.1 - 0.0049 16.7 1.6 0.012 15.5 1.1 1.7 1 0 0 1 1 1 1 FYVE zinc finger FYDLN_acid PF09538.5 EIE83703.1 - 0.012 16.2 2.4 0.012 16.2 1.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) zf-MIZ PF02891.15 EIE83703.1 - 0.021 14.3 10.9 0.059 12.9 7.5 1.8 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger zf-Apc11 PF12861.2 EIE83703.1 - 0.031 14.0 2.4 0.063 13.1 1.6 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger UIM PF02809.15 EIE83703.1 - 0.11 12.1 3.1 0.52 10.0 2.1 2.3 1 0 0 1 1 1 0 Ubiquitin interaction motif zf-Nse PF11789.3 EIE83703.1 - 1.1 8.8 7.7 7.5 6.1 5.7 2.1 1 1 1 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit CWC25 PF12542.3 EIE83703.1 - 5.9 7.4 15.7 1.6 9.2 3.6 2.4 2 0 0 2 2 2 0 Pre-mRNA splicing factor Ribosomal_S5 PF00333.15 EIE83705.1 - 2.4e-28 97.6 1.6 5.2e-28 96.5 1.1 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 EIE83705.1 - 2.5e-22 77.9 0.0 4.2e-22 77.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain PHP PF02811.14 EIE83706.1 - 4.1e-13 49.5 0.0 5.9e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 PHP domain Arteri_Gl PF00951.13 EIE83706.1 - 0.014 14.9 0.6 0.032 13.8 0.2 1.7 2 0 0 2 2 2 0 Arterivirus GL envelope glycoprotein Lung_7-TM_R PF06814.8 EIE83706.1 - 0.041 12.8 0.0 0.081 11.8 0.0 1.5 1 0 0 1 1 1 0 Lung seven transmembrane receptor Ribosomal_60s PF00428.14 EIE83707.1 - 9.5e-05 22.7 2.3 9.5e-05 22.7 1.6 2.0 2 0 0 2 2 2 1 60s Acidic ribosomal protein Nucleoplasmin PF03066.10 EIE83707.1 - 0.00045 19.7 4.4 0.00075 19.0 3.0 1.3 1 0 0 1 1 1 1 Nucleoplasmin DNA_pol_B_exo1 PF03104.14 EIE83707.1 - 0.0014 17.5 0.5 0.0021 17.0 0.0 1.4 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain HVSL PF09749.4 EIE83707.1 - 0.0024 16.9 0.9 0.0024 16.9 0.6 1.6 2 0 0 2 2 2 1 Uncharacterised conserved protein CENP-B_dimeris PF09026.5 EIE83707.1 - 0.0049 17.0 7.3 0.0093 16.1 5.0 1.4 1 0 0 1 1 1 1 Centromere protein B dimerisation domain Hom_end_hint PF05203.11 EIE83707.1 - 0.015 15.0 0.0 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 Hom_end-associated Hint Pox_RNA_Pol_19 PF05320.7 EIE83707.1 - 0.017 14.8 3.6 0.017 14.8 2.5 1.7 2 0 0 2 2 2 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit TFIIA PF03153.8 EIE83707.1 - 0.017 15.0 0.0 0.024 14.5 0.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TRAP_alpha PF03896.11 EIE83707.1 - 0.058 12.3 3.5 0.097 11.6 2.4 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RED_N PF07808.8 EIE83707.1 - 0.059 12.5 2.8 1.9 7.6 0.2 2.2 2 0 0 2 2 2 0 RED-like protein N-terminal region Utp14 PF04615.8 EIE83707.1 - 0.46 8.6 8.9 0.56 8.3 1.9 2.1 2 0 0 2 2 2 0 Utp14 protein VID27 PF08553.5 EIE83707.1 - 0.52 8.4 7.3 0.76 7.9 5.0 1.2 1 0 0 1 1 1 0 VID27 cytoplasmic protein NOA36 PF06524.7 EIE83707.1 - 0.53 9.4 7.0 0.9 8.7 4.9 1.3 1 0 0 1 1 1 0 NOA36 protein Radial_spoke PF04712.7 EIE83707.1 - 0.76 8.4 9.3 1.2 7.7 6.5 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein Nop14 PF04147.7 EIE83707.1 - 1.8 6.3 9.8 0.028 12.3 1.8 1.6 2 0 0 2 2 2 0 Nop14-like family Paf1 PF03985.8 EIE83707.1 - 3.1 6.4 11.5 6.2 5.4 8.0 1.4 1 0 0 1 1 1 0 Paf1 BSP_II PF05432.6 EIE83707.1 - 4.4 6.4 17.8 6.4 5.9 12.4 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Myc_N PF01056.13 EIE83707.1 - 5.5 6.0 13.4 9.8 5.2 9.3 1.3 1 0 0 1 1 1 0 Myc amino-terminal region NUDE_C PF04880.8 EIE83709.1 - 3.5e-11 43.7 12.3 3.5e-11 43.7 8.5 2.2 2 1 0 2 2 2 1 NUDE protein, C-terminal conserved region DUF3584 PF12128.3 EIE83709.1 - 3.6e-05 21.3 25.2 4.5e-05 21.0 17.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Filament PF00038.16 EIE83709.1 - 0.0056 16.1 8.3 0.0056 16.1 5.8 2.5 1 1 1 2 2 2 1 Intermediate filament protein TraF_2 PF13729.1 EIE83709.1 - 0.033 12.9 0.6 0.033 12.9 0.4 2.1 2 1 0 2 2 2 0 F plasmid transfer operon, TraF, protein HOOK PF05622.7 EIE83709.1 - 0.034 11.9 31.0 0.4 8.4 21.5 1.9 1 1 0 1 1 1 0 HOOK protein DUF869 PF05911.6 EIE83709.1 - 0.039 12.2 28.0 0.26 9.4 9.5 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) GAS PF13851.1 EIE83709.1 - 0.11 11.6 35.2 0.84 8.7 14.2 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding CENP-K PF11802.3 EIE83709.1 - 0.14 11.3 24.0 0.013 14.7 7.0 2.2 1 1 1 2 2 2 0 Centromere-associated protein K BRE1 PF08647.6 EIE83709.1 - 0.27 11.2 24.9 0.37 10.7 0.8 2.6 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase TPR_MLP1_2 PF07926.7 EIE83709.1 - 0.42 10.3 32.9 0.13 12.0 3.8 2.6 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Syntaxin-6_N PF09177.6 EIE83709.1 - 0.5 10.7 20.6 0.3 11.5 3.9 3.5 2 1 1 3 3 2 0 Syntaxin 6, N-terminal DUF2536 PF10750.4 EIE83709.1 - 0.52 9.9 5.0 1.9 8.1 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2536) DUF2937 PF11157.3 EIE83709.1 - 1.9 7.8 10.6 0.43 9.8 1.4 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2937) Baculo_PEP_C PF04513.7 EIE83709.1 - 2.5 7.9 12.3 9.4 6.0 2.4 2.9 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.6 EIE83709.1 - 4.2 7.3 7.8 3.2 7.6 0.0 3.2 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) APG6 PF04111.7 EIE83709.1 - 4.5 6.2 35.8 3.1 6.7 9.8 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 CENP-F_leu_zip PF10473.4 EIE83709.1 - 4.5 7.1 37.6 11 5.8 9.5 3.7 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIVA PF05103.8 EIE83709.1 - 5 7.1 27.1 0.55 10.2 6.3 3.0 1 1 1 2 2 2 0 DivIVA protein Laminin_II PF06009.7 EIE83709.1 - 5.4 6.7 22.5 1.5 8.5 0.2 3.9 2 1 2 4 4 4 0 Laminin Domain II Prefoldin_2 PF01920.15 EIE83709.1 - 5.7 6.7 31.0 0.24 11.1 2.8 4.6 1 1 2 4 4 4 0 Prefoldin subunit DUF730 PF05325.6 EIE83709.1 - 6.5 6.5 12.5 0.16 11.8 1.6 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF730) DUF3810 PF12725.2 EIE83709.1 - 6.5 5.5 10.6 7.1 5.4 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) CENP-Q PF13094.1 EIE83709.1 - 6.8 6.7 33.8 8.5 6.3 6.8 2.7 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Cytochrom_C1 PF02167.10 EIE83710.1 - 7.6e-87 290.5 0.0 9.5e-87 290.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 EIE83710.1 - 0.00015 21.8 0.0 0.00032 20.7 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 EIE83710.1 - 0.016 16.0 1.1 0.058 14.2 0.2 2.4 2 1 0 2 2 2 0 Cytochrome c DER1 PF04511.10 EIE83711.1 - 5.8e-21 74.8 5.0 7.1e-21 74.6 3.5 1.0 1 0 0 1 1 1 1 Der1-like family Redoxin PF08534.5 EIE83712.1 - 9.3e-33 112.8 0.0 1e-32 112.7 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EIE83712.1 - 7.9e-11 41.7 0.0 8.8e-11 41.5 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family DUF535 PF04393.8 EIE83712.1 - 0.079 11.8 0.0 0.098 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF535) Methyltransf_28 PF02636.12 EIE83713.1 - 2.5e-24 86.0 0.0 3.4e-24 85.6 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Acyl-CoA_dh_1 PF00441.19 EIE83714.1 - 2e-47 161.0 3.5 3e-47 160.4 2.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EIE83714.1 - 5.3e-24 84.9 1.3 9.6e-24 84.1 0.1 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EIE83714.1 - 2.3e-21 76.4 0.4 4.8e-21 75.4 0.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EIE83714.1 - 4.3e-18 64.5 0.1 8.8e-18 63.5 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Y_phosphatase PF00102.22 EIE83716.1 - 2.7e-68 229.8 1.1 7.6e-68 228.3 0.7 1.8 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.15 EIE83716.1 - 9.9e-12 45.2 0.0 4.9e-11 42.9 0.0 2.1 2 0 0 2 2 2 1 Rhodanese-like domain DSPc PF00782.15 EIE83716.1 - 0.0043 16.6 0.5 0.015 14.8 0.2 2.0 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EIE83716.1 - 0.0099 16.1 0.8 0.042 14.0 0.6 2.1 1 1 0 1 1 1 1 Tyrosine phosphatase family DUF2357 PF09823.4 EIE83717.1 - 0.0031 16.6 0.0 0.0076 15.3 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF2357) CHD5 PF04420.9 EIE83718.1 - 1.6e-28 99.3 0.1 1.9e-28 99.1 0.0 1.0 1 0 0 1 1 1 1 CHD5-like protein Fungal_trans PF04082.13 EIE83719.1 - 1.4e-10 40.4 6.1 2.6e-10 39.6 4.2 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain PQ-loop PF04193.9 EIE83720.1 - 8e-33 111.7 21.1 2.4e-19 68.6 3.5 3.0 3 0 0 3 3 3 2 PQ loop repeat UCR_6-4kD PF08997.5 EIE83720.1 - 0.047 13.4 3.6 0.4 10.4 1.0 2.6 1 1 1 2 2 2 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein S4 PF01479.20 EIE83721.1 - 3e-15 55.3 0.0 4.4e-15 54.8 0.0 1.3 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.1 EIE83721.1 - 0.00011 21.7 0.0 0.00026 20.5 0.0 1.6 2 0 0 2 2 2 1 S4 domain Ub-Mut7C PF14451.1 EIE83721.1 - 0.04 13.4 0.0 0.072 12.6 0.0 1.3 1 0 0 1 1 1 0 Mut7-C ubiquitin TGS PF02824.16 EIE83721.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 TGS domain HNH PF01844.18 EIE83722.1 - 0.036 13.9 0.0 0.052 13.4 0.0 1.3 1 0 0 1 1 1 0 HNH endonuclease ACCA PF03255.9 EIE83724.1 - 0.039 13.4 0.8 0.072 12.6 0.1 1.8 2 1 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF1690 PF07956.6 EIE83724.1 - 0.055 13.4 9.1 0.078 12.9 6.3 1.2 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) APG6 PF04111.7 EIE83724.1 - 1.8 7.5 6.4 2.3 7.1 4.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4415 PF14384.1 EIE83725.1 - 0.07 13.2 0.0 0.083 13.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4415) DDE_3 PF13358.1 EIE83725.1 - 0.071 12.8 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 DDE superfamily endonuclease Gcd10p PF04189.8 EIE83725.1 - 0.074 12.1 0.0 0.081 12.0 0.0 1.0 1 0 0 1 1 1 0 Gcd10p family EF-hand_7 PF13499.1 EIE83726.1 - 0.058 13.5 0.0 0.079 13.1 0.0 1.5 1 1 0 1 1 1 0 EF-hand domain pair HTH_Tnp_Tc5 PF03221.11 EIE83726.1 - 0.08 12.7 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain Cullin PF00888.17 EIE83727.1 - 3.9e-126 421.9 27.1 3.9e-126 421.9 18.8 1.9 2 0 0 2 2 2 1 Cullin family TRAPPC10 PF12584.3 EIE83727.1 - 2.2e-22 79.1 0.0 6.5e-22 77.6 0.0 1.8 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Cullin_Nedd8 PF10557.4 EIE83727.1 - 2.9e-22 78.2 0.7 1e-21 76.5 0.5 2.1 1 0 0 1 1 1 1 Cullin protein neddylation domain Gryzun-like PF12742.2 EIE83727.1 - 0.0038 17.0 0.0 0.0091 15.7 0.0 1.6 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking Foie-gras_1 PF11817.3 EIE83727.1 - 0.0079 15.6 1.5 0.12 11.7 0.1 3.0 3 0 0 3 3 3 1 Foie gras liver health family 1 Ank PF00023.25 EIE83728.1 - 5.6e-17 60.6 3.2 2.4e-08 33.3 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 EIE83728.1 - 2.5e-15 56.5 0.2 1.7e-08 34.7 0.2 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 EIE83728.1 - 2.7e-14 53.2 0.4 2.9e-06 27.5 0.1 2.3 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EIE83728.1 - 2.8e-11 43.2 0.2 0.00033 20.7 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIE83728.1 - 1.3e-07 31.1 1.3 0.29 11.4 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat Senescence_reg PF04520.8 EIE83728.1 - 0.12 12.8 0.9 0.2 12.1 0.6 1.4 1 0 0 1 1 1 0 Senescence regulator Syntaphilin PF15290.1 EIE83728.1 - 0.12 11.7 1.2 0.25 10.8 0.8 1.4 1 0 0 1 1 1 0 Golgi-localised syntaxin-1-binding clamp DDE_3 PF13358.1 EIE83729.1 - 1.4e-11 44.2 0.1 1.6e-11 44.1 0.1 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF3013 PF11217.3 EIE83730.1 - 0.0031 17.2 1.2 0.0039 16.9 0.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3013) PHD PF00628.24 EIE83731.1 - 5.8e-06 25.8 12.4 5.8e-06 25.8 8.6 2.1 2 0 0 2 2 2 1 PHD-finger GATA PF00320.22 EIE83731.1 - 3.2e-05 23.1 6.0 3.2e-05 23.1 4.2 2.0 2 0 0 2 2 2 1 GATA zinc finger Xpo1 PF08389.7 EIE83733.1 - 6.8e-37 126.6 0.3 8e-36 123.1 0.1 3.0 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.14 EIE83733.1 - 9.2e-07 28.6 0.1 4e-05 23.4 0.0 3.3 3 0 0 3 3 3 1 Importin-beta N-terminal domain Myosin_head PF00063.16 EIE83734.1 - 4.8e-238 791.6 9.6 3.8e-151 504.5 0.8 2.3 1 1 1 2 2 2 2 Myosin head (motor domain) IQ PF00612.22 EIE83734.1 - 2.6e-16 57.6 42.9 1.2e-05 24.4 0.3 6.7 7 0 0 7 7 7 5 IQ calmodulin-binding motif AAA_22 PF13401.1 EIE83734.1 - 0.0018 18.3 0.0 0.01 15.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EIE83734.1 - 0.019 14.3 0.0 0.037 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA-like domain AAA_16 PF13191.1 EIE83734.1 - 0.029 14.3 0.1 0.28 11.1 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_19 PF13245.1 EIE83734.1 - 0.058 13.1 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain ABC_tran PF00005.22 EIE83734.1 - 0.64 10.3 5.5 0.69 10.2 0.1 3.0 3 1 0 3 3 3 0 ABC transporter zf-U11-48K PF05253.7 EIE83735.1 - 0.05 13.3 0.8 0.11 12.2 0.5 1.6 1 0 0 1 1 1 0 U11-48K-like CHHC zinc finger Sec20 PF03908.8 EIE83735.1 - 0.077 12.7 0.3 0.19 11.4 0.2 1.7 1 0 0 1 1 1 0 Sec20 Vac_Fusion PF02346.11 EIE83735.1 - 0.086 12.2 0.5 0.25 10.7 0.3 1.9 1 0 0 1 1 1 0 Chordopoxvirus fusion protein bZIP_1 PF00170.16 EIE83735.1 - 8 6.4 7.6 6.7 6.7 0.1 3.0 3 0 0 3 3 3 0 bZIP transcription factor MAP1B_neuraxin PF00414.12 EIE83738.1 - 0.72 9.2 4.4 4.8 6.7 0.3 2.5 2 0 0 2 2 2 0 Neuraxin and MAP1B repeat Lipase_3 PF01764.20 EIE83739.1 - 1.9e-07 30.8 0.0 4e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) UPF0227 PF05728.7 EIE83739.1 - 0.069 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Abhydrolase_5 PF12695.2 EIE83739.1 - 0.099 12.3 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2974 PF11187.3 EIE83739.1 - 0.12 11.7 0.2 0.2 10.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Pro_Al_protease PF02983.9 EIE83740.1 - 0.24 11.4 1.2 8.6 6.4 0.1 2.2 2 0 0 2 2 2 0 Alpha-lytic protease prodomain RabGAP-TBC PF00566.13 EIE83741.1 - 1.2e-33 116.4 1.4 1.2e-33 116.4 0.9 4.0 4 1 0 4 4 4 1 Rab-GTPase-TBC domain Cep57_CLD_2 PF14197.1 EIE83741.1 - 0.11 12.4 13.9 0.084 12.8 2.5 2.9 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 DUF2968 PF11180.3 EIE83741.1 - 0.63 9.4 11.4 0.67 9.2 7.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2968) APG6 PF04111.7 EIE83741.1 - 0.66 8.9 21.0 1.2 8.1 14.6 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF972 PF06156.8 EIE83741.1 - 0.81 10.0 24.1 0.89 9.9 4.5 3.3 2 1 2 4 4 4 0 Protein of unknown function (DUF972) KIAA1430 PF13879.1 EIE83741.1 - 4.1 7.8 17.9 0.37 11.2 7.8 2.7 2 1 1 3 3 3 0 KIAA1430 homologue IncA PF04156.9 EIE83741.1 - 4.3 6.8 19.3 53 3.3 13.4 2.2 1 1 0 1 1 1 0 IncA protein DivIC PF04977.10 EIE83742.1 - 0.0052 16.2 1.6 0.016 14.6 1.1 1.8 1 0 0 1 1 1 1 Septum formation initiator Lebercilin PF15619.1 EIE83742.1 - 0.012 15.0 2.4 0.012 15.0 1.7 1.5 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease TSC22 PF01166.13 EIE83742.1 - 0.084 12.8 0.1 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family Golgin_A5 PF09787.4 EIE83742.1 - 0.13 10.8 1.5 0.16 10.4 1.1 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 TMF_TATA_bd PF12325.3 EIE83742.1 - 0.23 11.2 1.0 0.48 10.1 0.1 1.9 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding Cep57_CLD_2 PF14197.1 EIE83742.1 - 0.29 11.1 3.3 0.47 10.4 1.6 1.8 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Stork_head PF10264.4 EIE83743.1 - 0.12 12.6 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix Storkhead-box1 domain Fumble PF03630.9 EIE83745.1 - 7.4e-130 432.7 5.5 2.5e-128 427.7 3.8 2.0 1 1 0 1 1 1 1 Fumble Arrestin_N PF00339.24 EIE83746.1 - 1.6e-10 41.0 0.1 2.9e-07 30.4 0.0 2.6 2 1 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Ras PF00071.17 EIE83747.1 - 4.3e-59 198.5 0.1 5.1e-59 198.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIE83747.1 - 1.8e-19 70.4 0.0 2.6e-19 69.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIE83747.1 - 1.9e-12 46.7 0.0 2.1e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EIE83747.1 - 1.5e-05 24.2 0.0 1.9e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EIE83747.1 - 2.3e-05 24.3 0.0 4.6e-05 23.3 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EIE83747.1 - 0.0002 20.8 0.0 0.00043 19.7 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EIE83747.1 - 0.0054 15.9 0.0 0.011 14.9 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Big_3_2 PF12245.3 EIE83747.1 - 0.0068 15.9 0.1 1.6 8.3 0.0 2.4 2 0 0 2 2 2 1 Bacterial Ig-like domain (group 3) AAA_14 PF13173.1 EIE83747.1 - 0.017 14.9 0.0 0.029 14.2 0.0 1.4 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 EIE83747.1 - 0.021 14.0 0.1 0.099 11.8 0.0 1.9 2 1 0 3 3 3 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 EIE83747.1 - 0.023 14.8 0.0 0.1 12.7 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EIE83747.1 - 0.032 14.2 0.2 0.061 13.3 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain G-alpha PF00503.15 EIE83747.1 - 0.06 12.0 0.1 2 6.9 0.0 2.1 1 1 1 2 2 2 0 G-protein alpha subunit Amidase02_C PF12123.3 EIE83747.1 - 0.12 12.0 0.0 0.54 9.9 0.0 2.0 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase EamA PF00892.15 EIE83748.1 - 1.6e-06 28.1 24.8 6.3e-05 23.0 10.2 2.1 2 0 0 2 2 2 2 EamA-like transporter family DUF914 PF06027.7 EIE83748.1 - 3e-05 23.0 6.3 3.6e-05 22.7 4.4 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) EmrE PF13536.1 EIE83748.1 - 0.0051 16.9 18.4 0.061 13.5 0.1 2.8 2 1 1 3 3 3 2 Multidrug resistance efflux transporter EIID-AGA PF03613.9 EIE83748.1 - 0.92 8.3 6.8 0.093 11.6 0.6 2.1 2 0 0 2 2 2 0 PTS system mannose/fructose/sorbose family IID component TPT PF03151.11 EIE83748.1 - 1 9.0 16.5 0.4 10.3 5.3 2.1 2 0 0 2 2 2 0 Triose-phosphate Transporter family Spc97_Spc98 PF04130.8 EIE83749.1 - 4.8e-124 414.6 8.0 6e-124 414.3 5.6 1.0 1 0 0 1 1 1 1 Spc97 / Spc98 family DUF544 PF04424.8 EIE83749.1 - 0.014 15.1 0.0 0.069 12.9 0.0 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF544) DUF619 PF04768.8 EIE83750.1 - 1.1e-44 151.9 0.2 2.1e-44 150.9 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF619) Ribosomal_S10 PF00338.17 EIE83752.1 - 1.4e-31 108.1 0.7 1.9e-31 107.7 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e GRIM-19 PF06212.7 EIE83753.1 - 1.2e-35 122.0 0.0 1.4e-35 121.8 0.0 1.0 1 0 0 1 1 1 1 GRIM-19 protein Polysacc_lyase PF14099.1 EIE83754.1 - 0.00059 19.5 0.9 0.00084 19.0 0.6 1.4 1 1 0 1 1 1 1 Polysaccharide lyase bZIP_2 PF07716.10 EIE83755.1 - 5.3e-07 29.3 9.7 6.4e-07 29.0 6.0 1.6 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 EIE83755.1 - 2.2e-05 24.2 12.3 4.1e-05 23.4 8.5 1.5 1 0 0 1 1 1 1 bZIP transcription factor Cep57_CLD_2 PF14197.1 EIE83755.1 - 0.0015 18.4 7.1 0.0026 17.6 4.9 1.4 1 0 0 1 1 1 1 Centrosome localisation domain of PPC89 Spc42p PF11544.3 EIE83755.1 - 0.012 15.5 3.3 0.027 14.4 2.3 1.6 1 0 0 1 1 1 0 Spindle pole body component Spc42p DUF2400 PF09674.5 EIE83755.1 - 0.032 13.9 0.8 0.045 13.4 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) bZIP_Maf PF03131.12 EIE83755.1 - 0.068 13.4 8.9 0.12 12.7 6.2 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor DUF904 PF06005.7 EIE83755.1 - 0.07 13.4 2.6 0.14 12.4 1.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DUF4164 PF13747.1 EIE83755.1 - 0.08 13.0 4.0 0.12 12.4 2.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) DivIC PF04977.10 EIE83755.1 - 0.22 11.0 4.2 0.1 12.1 1.0 1.8 1 1 0 1 1 1 0 Septum formation initiator IncA PF04156.9 EIE83755.1 - 0.36 10.4 3.7 0.63 9.6 2.6 1.3 1 1 0 1 1 1 0 IncA protein HALZ PF02183.13 EIE83755.1 - 0.38 10.4 4.1 0.83 9.4 2.8 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper Glyco_hydro_45 PF02015.11 EIE83756.1 - 3.8e-77 258.9 20.7 4.7e-77 258.5 14.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 AMP-binding PF00501.23 EIE83757.1 - 1.7e-30 105.7 0.0 2.8e-24 85.3 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme Tim44 PF04280.10 EIE83760.1 - 1.1e-20 74.1 0.1 1.7e-20 73.4 0.1 1.3 1 0 0 1 1 1 1 Tim44-like domain MBA1 PF07961.6 EIE83760.1 - 1.8e-11 43.3 0.0 2.4e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 MBA1-like protein Saf-Nte_pilin PF09460.5 EIE83760.1 - 0.11 12.2 0.5 15 5.3 0.0 2.5 2 1 0 2 2 2 0 Saf-pilin pilus formation protein UPRTase PF14681.1 EIE83761.1 - 1.1e-69 233.7 0.0 2.2e-69 232.8 0.0 1.4 1 1 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EIE83761.1 - 0.0001 22.0 0.0 0.00015 21.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain tRNA_edit PF04073.10 EIE83763.1 - 8.4e-09 35.3 0.0 1.3e-08 34.6 0.0 1.4 1 1 0 1 1 1 1 Aminoacyl-tRNA editing domain EzrA PF06160.7 EIE83763.1 - 0.0069 14.6 0.2 0.01 14.0 0.1 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Zn_clus PF00172.13 EIE83765.1 - 1.1e-05 25.2 11.8 2.8e-05 23.9 8.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.27 EIE83767.1 - 0.00093 18.9 1.1 2.8 7.9 0.0 3.4 4 0 0 4 4 4 2 WD domain, G-beta repeat PD40 PF07676.7 EIE83767.1 - 0.021 14.5 0.0 0.048 13.3 0.0 1.6 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat DUF2057 PF09829.4 EIE83767.1 - 0.021 14.4 2.9 0.024 14.3 1.4 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) SdiA-regulated PF06977.6 EIE83767.1 - 0.022 13.6 0.2 0.046 12.6 0.1 1.5 1 1 0 1 1 1 0 SdiA-regulated Hira PF07569.6 EIE83767.1 - 0.067 12.4 0.5 3.3 6.8 0.1 2.4 2 1 0 2 2 2 0 TUP1-like enhancer of split Pkinase PF00069.20 EIE83768.1 - 4.3e-61 206.3 0.0 5.1e-61 206.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE83768.1 - 1.4e-24 86.5 0.0 2.2e-24 85.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE83768.1 - 6.2e-08 31.9 0.0 6.8e-07 28.5 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EIE83768.1 - 0.002 17.9 0.0 0.0038 17.0 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EIE83768.1 - 0.02 14.4 0.0 0.031 13.8 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase PEN-2 PF10251.4 EIE83771.1 - 0.11 12.7 0.8 0.2 11.9 0.5 1.6 1 1 0 1 1 1 0 Presenilin enhancer-2 subunit of gamma secretase APOBEC_N PF08210.6 EIE83771.1 - 0.13 11.8 0.1 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 APOBEC-like N-terminal domain MFS_1 PF07690.11 EIE83772.1 - 3.2e-37 128.0 17.0 1.7e-35 122.4 6.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIE83772.1 - 2.2e-12 46.2 9.2 3.2e-12 45.7 6.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter DUF1279 PF06916.8 EIE83773.1 - 1.9e-16 60.1 0.2 2.2e-16 59.8 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) GPI2 PF06432.6 EIE83775.1 - 0.15 11.3 0.1 0.15 11.3 0.1 2.0 2 0 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase zf-C2H2_4 PF13894.1 EIE83777.1 - 7.1e-05 22.8 10.4 0.021 15.1 0.2 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EIE83777.1 - 0.0011 19.1 16.7 0.01 16.1 0.6 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIE83777.1 - 0.025 14.8 9.9 0.59 10.5 0.3 3.1 3 0 0 3 3 3 0 Zinc-finger double domain Fer2 PF00111.22 EIE83777.1 - 0.48 10.2 2.7 2 8.2 0.0 2.9 3 0 0 3 3 3 0 2Fe-2S iron-sulfur cluster binding domain Sad1_UNC PF07738.8 EIE83778.1 - 7.6e-36 122.8 0.1 1.5e-35 121.9 0.0 1.5 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal CTDII PF01556.13 EIE83779.1 - 7.6e-15 54.5 0.3 5.5e-13 48.6 0.0 2.7 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ PF00226.26 EIE83779.1 - 7.9e-12 44.7 0.9 1e-07 31.5 0.2 2.9 2 1 1 3 3 3 2 DnaJ domain HSF_DNA-bind PF00447.12 EIE83780.1 - 7e-33 112.9 1.4 7e-33 112.9 1.0 2.2 3 1 0 3 3 3 1 HSF-type DNA-binding RolB_RolC PF02027.12 EIE83780.1 - 0.033 13.3 0.3 0.056 12.6 0.2 1.4 1 0 0 1 1 1 0 RolB/RolC glucosidase family IncA PF04156.9 EIE83780.1 - 1.6 8.2 15.7 1.3 8.6 9.8 1.5 1 1 1 2 2 2 0 IncA protein HCNGP PF07818.8 EIE83781.1 - 9.2e-25 86.5 0.1 3.6e-24 84.6 0.0 1.9 1 1 1 2 2 2 1 HCNGP-like protein Med15_fungi PF05397.7 EIE83781.1 - 0.099 12.6 0.4 0.2 11.6 0.3 1.4 1 0 0 1 1 1 0 Mediator complex subunit 15 Abhydrolase_6 PF12697.2 EIE83782.1 - 5.1e-13 49.4 0.0 7.3e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIE83782.1 - 5.8e-10 39.1 0.0 7e-09 35.5 0.0 2.3 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIE83782.1 - 0.00011 22.0 0.0 0.0002 21.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.6 EIE83782.1 - 0.016 14.3 0.0 0.026 13.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) GTP_EFTU PF00009.22 EIE83783.1 - 6.6e-57 191.9 0.0 1.2e-56 191.1 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EIE83783.1 - 9.7e-37 125.1 0.0 2.4e-36 123.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EIE83783.1 - 5e-16 58.5 1.1 5e-16 58.5 0.7 2.4 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EIE83783.1 - 0.00097 19.0 0.3 0.0029 17.5 0.2 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 EIE83783.1 - 0.0013 18.3 0.4 0.0013 18.3 0.3 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 4 Semialdhyde_dhC PF02774.13 EIE83783.1 - 0.12 12.2 0.3 0.32 10.8 0.0 1.8 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain Methyltransf_11 PF08241.7 EIE83784.1 - 8.6e-13 48.6 0.0 1.4e-12 47.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIE83784.1 - 1.1e-10 41.5 0.0 1.3e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIE83784.1 - 3.5e-09 36.4 0.0 6.1e-09 35.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIE83784.1 - 6.5e-07 28.6 0.0 1.6e-06 27.4 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EIE83784.1 - 8.6e-07 29.2 0.0 1.6e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIE83784.1 - 1.5e-06 28.6 0.1 5.5e-06 26.7 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIE83784.1 - 0.0014 19.1 0.0 0.0073 16.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EIE83784.1 - 0.0069 15.4 0.0 0.028 13.4 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_8 PF05148.10 EIE83784.1 - 0.0075 15.9 0.0 0.011 15.3 0.0 1.5 1 1 0 1 1 1 1 Hypothetical methyltransferase CheR PF01739.13 EIE83784.1 - 0.0092 15.2 0.0 0.19 10.9 0.0 2.3 2 1 0 2 2 2 1 CheR methyltransferase, SAM binding domain MetW PF07021.7 EIE83784.1 - 0.034 13.5 0.0 0.062 12.6 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_2 PF00891.13 EIE83784.1 - 0.071 12.2 0.0 0.079 12.1 0.0 1.1 1 0 0 1 1 1 0 O-methyltransferase PK PF00224.16 EIE83785.1 - 3.6e-141 469.8 0.8 4.4e-141 469.5 0.6 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 EIE83785.1 - 1.7e-28 98.4 0.0 6e-28 96.7 0.0 1.9 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 EIE83785.1 - 0.0057 15.5 0.7 0.017 13.9 0.6 1.8 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family CNF1 PF05785.7 EIE83785.1 - 0.096 11.5 0.1 0.16 10.8 0.0 1.4 1 1 0 1 1 1 0 Rho-activating domain of cytotoxic necrotizing factor Mit_ribos_Mrp51 PF11709.3 EIE83786.1 - 1.1e-18 67.5 7.4 9.1e-14 51.3 4.4 3.7 2 1 0 2 2 2 2 Mitochondrial ribosomal protein subunit GTPase_Cys_C PF12631.2 EIE83787.1 - 0.12 12.8 0.0 0.24 11.8 0.0 1.6 1 1 0 1 1 1 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE Cyt-b5 PF00173.23 EIE83788.1 - 0.0054 16.5 0.1 0.0057 16.4 0.1 1.4 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Epimerase PF01370.16 EIE83789.1 - 1.4e-44 152.3 0.0 1.7e-44 152.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EIE83789.1 - 1.9e-11 43.3 0.1 4.3e-07 29.0 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.14 EIE83789.1 - 6.1e-11 41.5 0.0 8.8e-11 41.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EIE83789.1 - 5.3e-10 38.6 0.0 6.7e-10 38.3 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EIE83789.1 - 7.1e-09 34.9 0.1 0.0001 21.3 0.1 2.8 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EIE83789.1 - 0.0001 22.3 0.0 0.00015 21.8 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EIE83789.1 - 0.009 15.9 0.0 0.019 14.8 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase IPK PF03770.11 EIE83790.1 - 1.9e-44 151.6 0.1 3.5e-44 150.8 0.1 1.4 1 0 0 1 1 1 1 Inositol polyphosphate kinase CDP-OH_P_transf PF01066.16 EIE83792.1 - 6.6e-17 61.6 3.8 1.5e-16 60.5 2.6 1.6 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase InvH PF04741.7 EIE83795.1 - 2.8 7.7 5.3 8 6.3 0.5 2.2 1 1 1 2 2 2 0 InvH outer membrane lipoprotein Ded_cyto PF06920.8 EIE83796.1 - 1.5e-38 131.9 0.6 5.2e-38 130.1 0.3 2.1 2 0 0 2 2 2 1 Dedicator of cytokinesis DOCK-C2 PF14429.1 EIE83796.1 - 2.8e-29 102.0 1.4 1.7e-26 92.9 0.1 3.8 2 1 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins UCH PF00443.24 EIE83798.1 - 4.6e-42 143.9 7.8 4.6e-41 140.7 5.4 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EIE83798.1 - 7.9e-12 45.2 17.9 2e-09 37.3 3.0 3.1 3 0 0 3 3 3 3 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EIE83798.1 - 0.037 14.1 1.5 0.037 14.1 1.0 3.7 3 1 1 4 4 4 0 Zn-finger in ubiquitin-hydrolases and other protein Zn_ribbon_2 PF12674.2 EIE83798.1 - 0.037 14.3 6.0 0.053 13.8 0.5 2.6 2 0 0 2 2 2 0 Putative zinc ribbon domain LSM PF01423.17 EIE83800.1 - 1.8e-20 72.2 0.1 2.3e-20 71.8 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EIE83800.1 - 0.0025 17.6 0.0 0.0031 17.3 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF669 PF05037.8 EIE83800.1 - 0.045 13.6 0.0 0.062 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF669) Nbas_N PF15492.1 EIE83800.1 - 0.057 12.5 0.0 0.072 12.1 0.0 1.0 1 0 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal DUF3671 PF12420.3 EIE83802.1 - 0.0074 16.2 0.2 0.0079 16.1 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function ATG27 PF09451.5 EIE83802.1 - 0.0089 15.2 0.0 0.0094 15.2 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 DNAPolymera_Pol PF11590.3 EIE83803.1 - 0.23 11.1 0.7 16 5.2 1.1 2.6 2 1 0 2 2 2 0 DNA polymerase catalytic subunit Pol Cation_efflux PF01545.16 EIE83804.1 - 7e-71 238.6 9.9 8.9e-71 238.2 6.8 1.1 1 0 0 1 1 1 1 Cation efflux family DUF4010 PF13194.1 EIE83804.1 - 0.23 10.7 8.0 0.17 11.1 2.5 2.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4010) AA_permease_2 PF13520.1 EIE83804.1 - 0.4 9.1 9.6 0.024 13.1 1.7 2.0 2 0 0 2 2 2 0 Amino acid permease Ribosomal_L34 PF00468.12 EIE83805.1 - 9.7e-21 73.1 9.1 1.5e-20 72.5 6.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L34 Dus PF01207.12 EIE83806.1 - 2e-51 174.6 0.0 2.4e-51 174.4 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.16 EIE83806.1 - 0.0037 16.5 0.0 0.012 14.8 0.0 1.7 2 0 0 2 2 2 1 Histidine biosynthesis protein Plasmod_dom_1 PF09715.5 EIE83806.1 - 0.021 14.7 0.2 0.046 13.6 0.1 1.7 1 0 0 1 1 1 0 Plasmodium protein of unknown function (Plasmod_dom_1) Ribosomal_L27e PF01777.13 EIE83807.1 - 3e-09 36.8 5.1 3.4e-09 36.7 3.6 1.0 1 0 0 1 1 1 1 Ribosomal L27e protein family Cnl2_NKP2 PF09447.5 EIE83807.1 - 0.066 12.8 0.2 0.076 12.7 0.1 1.2 1 0 0 1 1 1 0 Cnl2/NKP2 family protein Ribosomal_S2 PF00318.15 EIE83808.1 - 4.8e-43 146.8 0.2 6.2e-21 74.6 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 Ras PF00071.17 EIE83809.1 - 1.5e-46 157.7 0.1 2.1e-46 157.2 0.1 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIE83809.1 - 2e-11 44.4 0.1 3.9e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIE83809.1 - 2.9e-09 36.4 0.2 3.7e-09 36.0 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EIE83809.1 - 8e-05 22.1 0.0 0.00011 21.7 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EIE83809.1 - 0.06 12.4 0.1 0.071 12.2 0.1 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region zf-CHCC PF10276.4 EIE83810.1 - 1.4e-17 63.1 1.5 2.1e-17 62.6 1.1 1.2 1 0 0 1 1 1 1 Zinc-finger domain TPR_11 PF13414.1 EIE83811.1 - 4.5e-20 71.0 2.2 1.8e-14 53.1 0.0 2.9 3 0 0 3 3 3 2 TPR repeat TPR_1 PF00515.23 EIE83811.1 - 5.7e-14 51.0 2.9 0.00011 21.6 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EIE83811.1 - 5.6e-12 44.6 2.1 0.0021 17.8 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 EIE83811.1 - 4.8e-08 32.2 2.1 0.1 12.4 0.2 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 EIE83811.1 - 4.6e-07 29.6 0.7 0.0019 18.0 0.2 3.5 2 1 1 3 3 3 3 Tetratricopeptide repeat UBA PF00627.26 EIE83811.1 - 1.1e-05 25.1 0.4 4.8e-05 23.0 0.0 2.4 3 0 0 3 3 3 1 UBA/TS-N domain TPR_16 PF13432.1 EIE83811.1 - 1.3e-05 25.7 0.7 0.71 10.6 0.0 3.7 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EIE83811.1 - 0.0023 17.5 0.2 3.6 7.6 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EIE83811.1 - 0.024 15.2 0.2 5.2 7.9 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 EIE83811.1 - 0.033 14.3 0.3 3.1 8.2 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat AP2 PF00847.15 EIE83811.1 - 0.047 13.8 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 AP2 domain Ribosomal_S8e PF01201.17 EIE83812.1 - 2e-40 137.9 6.9 8.5e-39 132.7 4.8 2.2 1 1 0 1 1 1 1 Ribosomal protein S8e Ribosomal_L13e PF01294.13 EIE83814.1 - 1.3e-78 262.5 7.1 1.9e-78 262.0 4.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e G_glu_transpept PF01019.16 EIE83815.1 - 9.9e-78 261.8 0.8 2.7e-43 148.2 0.0 3.0 1 1 2 3 3 3 3 Gamma-glutamyltranspeptidase Ret_tiss PF10044.4 EIE83816.1 - 0.042 14.3 0.2 4.6 7.8 0.1 2.8 2 0 0 2 2 2 0 Retinal tissue protein Pkinase PF00069.20 EIE83819.1 - 1.9e-62 210.7 0.0 9e-61 205.2 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE83819.1 - 1.9e-27 96.0 0.0 3e-25 88.7 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE83819.1 - 3.6e-06 26.1 0.0 9.2e-05 21.5 0.0 2.1 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 EIE83819.1 - 0.004 16.5 0.6 0.055 12.8 0.4 2.2 1 1 0 1 1 1 1 RIO1 family APH PF01636.18 EIE83819.1 - 0.023 14.4 0.6 0.11 12.2 0.1 2.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family Lipase_3 PF01764.20 EIE83820.1 - 2.2e-12 46.7 0.0 4.7e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) F_bP_aldolase PF01116.15 EIE83821.1 - 3e-99 331.7 0.0 3.4e-99 331.5 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Peptidase_C26 PF07722.8 EIE83821.1 - 0.072 12.5 0.1 0.82 9.0 0.0 2.1 2 0 0 2 2 2 0 Peptidase C26 DUF4065 PF13274.1 EIE83821.1 - 0.075 13.7 0.2 12 6.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4065) UQ_con PF00179.21 EIE83822.1 - 1.9e-46 156.9 0.0 2.6e-46 156.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EIE83822.1 - 5.6e-05 22.9 0.0 8.2e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EIE83822.1 - 0.001 18.9 0.0 0.0015 18.4 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 EIE83822.1 - 0.014 15.1 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 UEV domain PAP1 PF08601.5 EIE83822.1 - 1.7 8.2 8.9 2.1 7.9 6.2 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 SOG2 PF10428.4 EIE83822.1 - 3.3 6.2 7.4 4.2 5.9 5.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Lar_restr_allev PF14354.1 EIE83824.1 - 0.079 13.2 2.2 2 8.7 0.1 2.6 2 0 0 2 2 2 0 Restriction alleviation protein Lar Prok-RING_4 PF14447.1 EIE83824.1 - 0.69 9.4 4.8 9.3 5.8 0.1 3.1 3 1 0 3 3 3 0 Prokaryotic RING finger family 4 zf-piccolo PF05715.8 EIE83824.1 - 1.3 9.1 4.6 9 6.3 0.5 2.7 2 0 0 2 2 2 0 Piccolo Zn-finger zf-ISL3 PF14690.1 EIE83824.1 - 3.1 7.8 6.1 3.9 7.5 0.9 2.8 3 0 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 adh_short PF00106.20 EIE83825.1 - 3.6e-60 202.6 12.8 7.3e-30 104.0 1.8 2.3 2 0 0 2 2 2 2 short chain dehydrogenase MaoC_dehydratas PF01575.14 EIE83825.1 - 3e-31 107.3 0.0 7.5e-31 106.0 0.0 1.7 1 0 0 1 1 1 1 MaoC like domain KR PF08659.5 EIE83825.1 - 9.3e-29 100.3 7.1 1.5e-14 54.0 0.6 2.2 2 0 0 2 2 2 2 KR domain MaoC_dehydrat_N PF13452.1 EIE83825.1 - 1.8e-13 50.4 0.0 6.1e-13 48.7 0.0 1.9 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase THF_DHG_CYH_C PF02882.14 EIE83825.1 - 0.00023 20.2 2.0 0.09 11.8 0.2 2.5 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF4161 PF13722.1 EIE83825.1 - 0.054 13.7 0.4 0.29 11.4 0.0 2.1 2 0 0 2 2 2 0 C-terminal domain on CstA (DUF4161) UbiA PF01040.13 EIE83826.1 - 1.3e-23 83.5 17.6 1.5e-23 83.3 12.2 1.0 1 0 0 1 1 1 1 UbiA prenyltransferase family Peptidase_M16 PF00675.15 EIE83827.1 - 3.8e-41 140.3 0.2 2.8e-40 137.4 0.1 2.5 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EIE83827.1 - 1.5e-33 116.0 0.0 5.4e-19 68.5 0.0 2.5 2 0 0 2 2 2 2 Peptidase M16 inactive domain SEEEED PF14797.1 EIE83827.1 - 0.0064 16.6 0.5 0.015 15.4 0.3 1.5 1 0 0 1 1 1 1 Serine-rich region of AP3B1, clathrin-adaptor complex Malic_M PF03949.10 EIE83828.1 - 8e-78 261.5 0.0 1.3e-77 260.8 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 EIE83828.1 - 3.8e-74 248.1 0.0 7.3e-74 247.2 0.0 1.5 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain 2OG-FeII_Oxy_2 PF13532.1 EIE83829.1 - 4.9e-14 52.5 0.0 9.2e-12 45.1 0.0 2.3 1 1 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily Yip1 PF04893.12 EIE83829.1 - 6e-09 35.6 4.3 8.2e-09 35.1 3.0 1.2 1 0 0 1 1 1 1 Yip1 domain bZIP_2 PF07716.10 EIE83830.1 - 7.2e-09 35.3 9.3 7.2e-09 35.3 6.5 2.0 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.16 EIE83830.1 - 1.7e-07 31.0 7.0 3.6e-07 30.0 4.8 1.5 1 0 0 1 1 1 1 bZIP transcription factor DUF972 PF06156.8 EIE83830.1 - 0.0015 18.8 3.7 0.0022 18.3 2.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF972) DUF2400 PF09674.5 EIE83830.1 - 0.0018 18.0 2.1 0.0022 17.7 1.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2400) Phlebovirus_NSM PF07246.6 EIE83830.1 - 0.0039 16.3 4.9 0.0053 15.9 3.4 1.1 1 0 0 1 1 1 1 Phlebovirus nonstructural protein NS-M bZIP_Maf PF03131.12 EIE83830.1 - 0.0091 16.2 9.8 0.0091 16.2 6.8 1.5 2 0 0 2 2 1 1 bZIP Maf transcription factor TBPIP PF07106.8 EIE83830.1 - 0.011 15.3 3.1 0.015 14.8 2.2 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Snf7 PF03357.16 EIE83830.1 - 0.023 14.0 6.1 0.033 13.5 4.2 1.2 1 0 0 1 1 1 0 Snf7 M PF02370.11 EIE83830.1 - 0.025 14.8 4.3 0.13 12.6 0.4 2.6 1 1 1 2 2 2 0 M protein repeat Mit_ribos_Mrp51 PF11709.3 EIE83830.1 - 0.029 13.6 3.1 0.035 13.3 2.2 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit Shugoshin_N PF07558.6 EIE83830.1 - 0.12 12.0 4.1 0.23 11.2 2.8 1.4 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region DivIC PF04977.10 EIE83830.1 - 0.15 11.5 7.6 0.46 9.9 4.7 2.2 1 1 0 1 1 1 0 Septum formation initiator CCDC-167 PF15188.1 EIE83830.1 - 0.17 11.8 2.4 0.27 11.1 1.7 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Spc42p PF11544.3 EIE83830.1 - 0.17 11.8 5.9 0.076 12.9 2.4 1.6 1 1 1 2 2 2 0 Spindle pole body component Spc42p DUF4164 PF13747.1 EIE83830.1 - 0.34 11.0 5.6 0.33 11.1 3.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) V_ATPase_I PF01496.14 EIE83830.1 - 0.38 8.5 2.7 0.51 8.1 1.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6 PF04111.7 EIE83830.1 - 0.47 9.4 6.6 0.57 9.1 4.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Tho2 PF11262.3 EIE83830.1 - 0.5 9.3 5.0 0.68 8.9 3.5 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF948 PF06103.6 EIE83830.1 - 0.51 10.2 2.1 0.72 9.7 1.4 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) IncA PF04156.9 EIE83830.1 - 0.59 9.7 5.5 0.82 9.2 3.8 1.2 1 0 0 1 1 1 0 IncA protein HALZ PF02183.13 EIE83830.1 - 1.3 8.8 5.9 0.32 10.7 1.6 1.9 2 1 0 2 2 1 0 Homeobox associated leucine zipper DUF342 PF03961.8 EIE83830.1 - 1.8 6.9 4.7 2.1 6.6 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF349 PF03993.7 EIE83830.1 - 5.9 7.1 7.4 11 6.3 5.2 1.4 1 1 0 1 1 1 0 Domain of Unknown Function (DUF349) Aldo_ket_red PF00248.16 EIE83831.1 - 9.5e-37 126.3 0.1 1.3e-36 125.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Peptidase_M24 PF00557.19 EIE83834.1 - 2.6e-42 144.7 0.0 3.9e-42 144.1 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 EIE83834.1 - 1.6e-20 73.9 0.1 3.7e-17 63.0 0.0 2.9 2 1 1 3 3 3 2 Creatinase/Prolidase N-terminal domain E3_binding PF02817.12 EIE83834.1 - 0.14 11.8 0.0 0.78 9.4 0.0 2.3 2 0 0 2 2 2 0 e3 binding domain GrpE PF01025.14 EIE83835.1 - 0.21 11.0 13.4 0.38 10.2 9.3 1.5 1 1 0 1 1 1 0 GrpE Cofilin_ADF PF00241.15 EIE83836.1 - 3e-40 137.0 0.8 3.4e-40 136.8 0.6 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Cwf_Cwc_15 PF04889.7 EIE83837.1 - 0.001 18.8 7.2 0.0011 18.6 5.0 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein SEEEED PF14797.1 EIE83837.1 - 0.0033 17.5 15.7 0.0044 17.1 10.9 1.2 1 0 0 1 1 1 1 Serine-rich region of AP3B1, clathrin-adaptor complex AF-4 PF05110.8 EIE83837.1 - 0.0036 15.2 9.8 0.004 15.1 6.8 1.1 1 0 0 1 1 1 1 AF-4 proto-oncoprotein zf-CCHC_3 PF13917.1 EIE83837.1 - 0.0088 15.7 0.4 0.018 14.7 0.3 1.4 1 0 0 1 1 1 1 Zinc knuckle FAM60A PF15396.1 EIE83837.1 - 0.025 14.3 4.6 0.027 14.2 3.2 1.1 1 0 0 1 1 1 0 Protein Family FAM60A SR-25 PF10500.4 EIE83837.1 - 0.027 13.9 15.3 0.034 13.5 10.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein FAM104 PF15434.1 EIE83837.1 - 0.028 14.6 4.7 0.037 14.2 3.3 1.2 1 0 0 1 1 1 0 Family 104 RXT2_N PF08595.6 EIE83837.1 - 0.03 14.1 1.5 0.034 13.9 1.1 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF1754 PF08555.5 EIE83837.1 - 0.035 14.7 6.4 0.042 14.4 4.5 1.2 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) BLVR PF06375.6 EIE83837.1 - 0.054 13.3 5.2 0.064 13.0 3.6 1.3 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) PcfJ PF14284.1 EIE83837.1 - 0.12 11.8 1.0 0.14 11.6 0.7 1.1 1 0 0 1 1 1 0 PcfJ-like protein FancD2 PF14631.1 EIE83837.1 - 0.16 9.0 3.7 0.17 8.9 2.6 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease FAM176 PF14851.1 EIE83837.1 - 0.37 10.4 3.9 0.51 10.0 2.7 1.2 1 0 0 1 1 1 0 FAM176 family TFIIF_alpha PF05793.7 EIE83837.1 - 0.45 8.8 10.0 0.55 8.5 6.9 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF3827 PF12877.2 EIE83837.1 - 0.53 8.3 5.6 0.58 8.1 3.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) NPR3 PF03666.8 EIE83837.1 - 0.54 8.7 4.1 0.58 8.6 2.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Pap_E4 PF02711.9 EIE83837.1 - 1.2 10.0 5.9 1.9 9.3 4.0 1.5 1 1 0 1 1 1 0 E4 protein Uds1 PF15456.1 EIE83837.1 - 1.8 8.5 6.9 1.8 8.6 4.3 1.4 1 1 0 1 1 1 0 Up-regulated During Septation NST1 PF13945.1 EIE83837.1 - 4.6 7.2 12.0 7.5 6.5 8.3 1.5 1 1 0 1 1 1 0 Salt tolerance down-regulator Proteasome PF00227.21 EIE83838.1 - 3e-56 189.7 0.1 4.2e-56 189.2 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EIE83838.1 - 1.9e-15 55.8 0.1 3.3e-15 55.0 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature PAT1 PF09770.4 EIE83842.1 - 0.21 9.7 45.3 0.28 9.3 31.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DRY_EERY PF09750.4 EIE83842.1 - 0.3 11.2 10.6 0.71 9.9 7.3 1.7 1 0 0 1 1 1 0 Alternative splicing regulator Med15 PF09606.5 EIE83842.1 - 0.34 9.0 52.1 0.44 8.6 36.1 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4446 PF14584.1 EIE83842.1 - 5.1 6.9 7.6 10 5.8 5.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Sel1 PF08238.7 EIE83843.1 - 1.5e-25 89.0 10.9 6.3e-09 36.1 0.5 4.2 4 0 0 4 4 4 3 Sel1 repeat Cohesin_load PF10345.4 EIE83843.1 - 0.046 11.9 0.3 0.084 11.0 0.2 1.6 1 1 0 1 1 1 0 Cohesin loading factor TPR_11 PF13414.1 EIE83843.1 - 0.06 13.0 6.8 0.79 9.4 0.4 2.8 1 1 2 3 3 3 0 TPR repeat TPR_16 PF13432.1 EIE83843.1 - 0.071 13.8 0.5 0.56 10.9 0.1 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat EF-hand_1 PF00036.27 EIE83845.1 - 7e-09 34.3 2.2 2.3e-05 23.3 0.1 3.4 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 EIE83845.1 - 3.8e-08 33.3 4.5 0.00033 20.7 1.3 2.8 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EIE83845.1 - 1.8e-06 27.4 1.0 0.00069 19.1 0.0 3.1 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.1 EIE83845.1 - 6.8e-06 25.5 1.6 0.19 11.6 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.1 EIE83845.1 - 0.00051 19.2 0.6 0.0017 17.6 0.0 2.1 2 0 0 2 2 2 1 EF hand p25-alpha PF05517.7 EIE83845.1 - 0.02 15.1 0.1 0.053 13.7 0.0 1.8 1 1 1 2 2 2 0 p25-alpha EF-hand_4 PF12763.2 EIE83845.1 - 0.065 12.9 0.9 3.7 7.3 0.1 2.6 2 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand Latexin PF06907.7 EIE83845.1 - 0.086 11.9 0.1 0.16 11.1 0.0 1.5 1 1 0 1 1 1 0 Latexin NOC3p PF07540.6 EIE83845.1 - 0.099 12.9 0.2 0.23 11.7 0.1 1.6 1 0 0 1 1 1 0 Nucleolar complex-associated protein RE_TaqI PF09573.5 EIE83845.1 - 0.14 11.3 0.1 0.18 10.9 0.1 1.1 1 0 0 1 1 1 0 TaqI restriction endonuclease DUF543 PF04418.7 EIE83846.1 - 6.8e-24 83.6 0.0 7.7e-24 83.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF543) 2TM PF13239.1 EIE83846.1 - 0.0012 18.8 0.1 0.0013 18.7 0.1 1.3 1 0 0 1 1 1 1 2TM domain Cpn60_TCP1 PF00118.19 EIE83847.1 - 2.5e-136 455.1 8.9 2.9e-136 454.9 6.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF3271 PF11675.3 EIE83847.1 - 0.083 12.0 0.2 0.15 11.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3271) DnaB PF00772.16 EIE83848.1 - 0.056 13.3 2.3 0.81 9.5 0.1 2.1 1 1 1 2 2 2 0 DnaB-like helicase N terminal domain SCAN PF02023.12 EIE83848.1 - 7.3 6.1 10.0 6.6 6.2 3.7 2.1 1 1 1 2 2 2 0 SCAN domain Ank_4 PF13637.1 EIE83849.1 - 4.3e-06 27.0 0.0 9.4e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) KilA-N PF04383.8 EIE83849.1 - 8.7e-06 25.3 1.7 9.8e-05 21.9 0.2 2.9 2 1 0 2 2 2 1 KilA-N domain Ank PF00023.25 EIE83849.1 - 9.4e-06 25.1 0.1 2.2e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.2 EIE83849.1 - 9.5e-06 25.8 0.0 1.8e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EIE83849.1 - 2.7e-05 23.9 0.1 6.7e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeat Ank_5 PF13857.1 EIE83849.1 - 0.00096 19.3 0.0 0.0024 18.0 0.0 1.6 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ras PF00071.17 EIE83850.1 - 1e-56 190.7 0.0 1.2e-56 190.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIE83850.1 - 1.8e-18 67.1 0.0 2.7e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIE83850.1 - 8.2e-17 60.9 0.0 9.8e-17 60.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EIE83850.1 - 7.3e-10 38.3 0.0 9e-10 38.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EIE83850.1 - 1.4e-05 24.6 0.0 3.6e-05 23.2 0.0 1.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EIE83850.1 - 3.1e-05 23.9 0.0 5.1e-05 23.2 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Hpr_kinase_C PF07475.7 EIE83850.1 - 0.021 14.1 0.3 0.042 13.1 0.0 1.6 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_22 PF13401.1 EIE83850.1 - 0.064 13.4 0.0 0.15 12.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 EIE83850.1 - 0.088 11.9 0.1 0.2 10.8 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF258 Adap_comp_sub PF00928.16 EIE83851.1 - 7.8e-92 307.0 0.1 9.8e-92 306.7 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EIE83851.1 - 2.4e-06 27.2 1.7 1.4e-05 24.8 0.7 2.2 1 1 1 2 2 2 1 Clathrin adaptor complex small chain SH3_5 PF08460.5 EIE83851.1 - 0.1 12.5 0.2 0.26 11.2 0.2 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain WD40 PF00400.27 EIE83852.1 - 3.5e-28 96.4 10.8 1.5e-08 34.1 0.3 6.3 7 0 0 7 7 7 4 WD domain, G-beta repeat DUF3639 PF12341.3 EIE83852.1 - 0.0002 21.2 3.3 0.00028 20.7 1.4 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3639) BBS2_Mid PF14783.1 EIE83852.1 - 0.0033 17.1 3.6 0.25 11.1 0.1 4.1 3 1 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region CPDase PF07823.6 EIE83852.1 - 0.04 13.3 0.0 0.094 12.1 0.0 1.6 1 0 0 1 1 1 0 Cyclic phosphodiesterase-like protein DUF3312 PF11768.3 EIE83852.1 - 0.067 11.4 0.1 0.21 9.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) DNA_pol_alpha_N PF12254.3 EIE83852.1 - 0.84 9.5 11.1 0.018 14.8 2.4 2.2 2 0 0 2 2 2 0 DNA polymerase alpha subunit p180 N terminal YqzL PF14006.1 EIE83852.1 - 6.2 7.1 7.4 0.71 10.1 0.6 2.6 2 0 0 2 2 2 0 YqzL-like protein GST_C_3 PF14497.1 EIE83853.1 - 8.9e-07 29.3 0.0 1.8e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EIE83853.1 - 1.5e-06 28.1 0.6 8.4e-06 25.6 0.1 2.3 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EIE83853.1 - 0.0022 17.8 0.0 0.0061 16.4 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EIE83853.1 - 0.0093 16.1 0.0 0.021 15.0 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain CBM_48 PF02922.13 EIE83853.1 - 0.1 12.6 0.1 0.28 11.2 0.1 1.8 1 1 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) PCI_Csn8 PF10075.4 EIE83854.1 - 1.8e-29 102.3 0.9 3e-29 101.6 0.6 1.3 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 EIE83854.1 - 9.7e-27 93.8 3.0 1.4e-26 93.3 2.1 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family O-FucT PF10250.4 EIE83855.1 - 2.2e-07 30.3 0.6 2.1e-05 23.8 0.4 2.8 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase XG_FTase PF03254.8 EIE83855.1 - 0.074 11.5 0.0 0.13 10.7 0.0 1.4 1 0 0 1 1 1 0 Xyloglucan fucosyltransferase DUF1296 PF06972.6 EIE83855.1 - 0.15 12.0 1.1 5 7.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1296) Kelch_2 PF07646.10 EIE83856.1 - 0.016 14.9 0.1 0.034 13.9 0.0 1.5 1 0 0 1 1 1 0 Kelch motif Kelch_4 PF13418.1 EIE83856.1 - 0.051 13.3 0.0 0.092 12.5 0.0 1.4 1 0 0 1 1 1 0 Galactose oxidase, central domain Kelch_5 PF13854.1 EIE83856.1 - 0.061 13.2 0.3 0.12 12.3 0.2 1.4 1 0 0 1 1 1 0 Kelch motif Kelch_1 PF01344.20 EIE83857.1 - 1.1e-12 47.3 0.2 3.2e-06 26.5 0.1 2.4 2 1 0 2 2 2 2 Kelch motif Kelch_5 PF13854.1 EIE83857.1 - 3.1e-12 46.1 0.4 2.7e-07 30.3 0.0 2.3 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.1 EIE83857.1 - 2.8e-11 42.9 2.1 2.2e-05 24.1 0.1 3.0 2 1 0 2 2 2 2 Galactose oxidase, central domain Kelch_3 PF13415.1 EIE83857.1 - 2.9e-10 40.0 7.1 0.00048 20.2 0.2 3.4 3 1 0 3 3 3 3 Galactose oxidase, central domain Kelch_6 PF13964.1 EIE83857.1 - 3.3e-10 39.6 2.1 1.5e-06 28.1 0.1 2.6 1 1 1 2 2 2 2 Kelch motif Kelch_2 PF07646.10 EIE83857.1 - 1.5e-08 34.0 1.0 0.00018 21.1 0.1 2.5 2 1 0 2 2 2 2 Kelch motif DUF2962 PF11176.3 EIE83859.1 - 0.026 14.0 0.8 0.044 13.3 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2962) Fungal_trans PF04082.13 EIE83860.1 - 1.1e-05 24.4 1.6 3.1e-05 22.9 0.4 2.0 2 1 0 2 2 2 1 Fungal specific transcription factor domain RNA_pol_Rpb2_1 PF04563.10 EIE83861.1 - 0.024 13.5 0.4 0.046 12.6 0.3 1.4 1 0 0 1 1 1 0 RNA polymerase beta subunit WRKY PF03106.10 EIE83861.1 - 0.079 12.8 2.3 0.16 11.7 1.6 1.6 1 0 0 1 1 1 0 WRKY DNA -binding domain GAD-like PF08887.6 EIE83862.1 - 0.087 12.9 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 GAD-like domain zf-H2C2_2 PF13465.1 EIE83863.1 - 3.2e-16 58.7 14.6 4.8e-09 36.0 1.1 4.3 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.21 EIE83863.1 - 1e-15 56.9 21.6 8.2e-07 29.0 1.3 3.9 4 0 0 4 4 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIE83863.1 - 4.1e-15 54.9 16.9 1.7e-05 24.7 0.2 3.9 4 0 0 4 4 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EIE83863.1 - 1.7e-07 31.1 7.3 0.0068 16.5 0.1 3.8 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EIE83863.1 - 4.6e-05 23.4 8.9 1.3 9.2 0.2 4.4 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-BED PF02892.10 EIE83863.1 - 0.0018 18.0 6.3 0.31 10.8 0.1 3.5 2 1 1 3 3 3 1 BED zinc finger PyrI_C PF02748.10 EIE83863.1 - 0.02 14.2 1.1 1.3 8.4 0.0 2.7 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_6 PF13912.1 EIE83863.1 - 0.021 14.6 7.9 2.8 7.9 0.1 3.9 4 0 0 4 4 3 0 C2H2-type zinc finger zf-C2HC_2 PF13913.1 EIE83863.1 - 0.075 12.7 15.9 0.13 11.9 0.9 3.2 3 1 0 3 3 3 0 zinc-finger of a C2HC-type LIM PF00412.17 EIE83863.1 - 0.076 13.1 3.6 0.15 12.1 2.2 1.7 1 1 1 2 2 2 0 LIM domain Zn_Tnp_IS1595 PF12760.2 EIE83863.1 - 0.082 12.7 7.3 0.37 10.6 1.8 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-C2H2_2 PF12756.2 EIE83863.1 - 0.14 12.3 0.5 0.14 12.3 0.3 2.8 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-CHY PF05495.7 EIE83863.1 - 0.15 12.2 5.9 0.17 12.0 3.2 1.6 1 1 0 1 1 1 0 CHY zinc finger IBR PF01485.16 EIE83863.1 - 0.18 11.6 9.1 0.12 12.2 4.1 2.3 1 1 1 2 2 2 0 IBR domain Zn-ribbon_8 PF09723.5 EIE83863.1 - 0.24 11.3 6.5 8.3 6.4 0.0 3.2 2 1 1 3 3 3 0 Zinc ribbon domain zf-AN1 PF01428.11 EIE83863.1 - 0.38 10.6 10.4 1.1 9.1 1.8 2.8 1 1 1 2 2 2 0 AN1-like Zinc finger zf-Di19 PF05605.7 EIE83863.1 - 1.6 8.9 7.7 6.6 6.9 0.0 2.8 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding SWIB PF02201.13 EIE83864.1 - 0.0058 16.2 0.1 0.13 11.9 0.0 3.0 2 1 0 2 2 2 1 SWIB/MDM2 domain SSP160 PF06933.6 EIE83864.1 - 0.026 12.5 2.2 0.037 12.0 1.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DDE_3 PF13358.1 EIE83865.1 - 1.3e-17 63.8 0.1 1.4e-17 63.7 0.1 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE83865.1 - 0.00057 19.9 0.0 0.00066 19.7 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_ISAZ013 PF07592.6 EIE83865.1 - 0.08 11.6 0.2 0.088 11.5 0.1 1.2 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain GAD-like PF08887.6 EIE83867.1 - 0.087 12.9 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 GAD-like domain zf-H2C2_2 PF13465.1 EIE83868.1 - 3.2e-16 58.7 14.6 4.8e-09 36.0 1.1 4.3 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.21 EIE83868.1 - 1e-15 56.9 21.6 8.2e-07 29.0 1.3 3.9 4 0 0 4 4 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIE83868.1 - 4.1e-15 54.9 16.9 1.7e-05 24.7 0.2 3.9 4 0 0 4 4 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EIE83868.1 - 1.7e-07 31.1 7.3 0.0068 16.5 0.1 3.8 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EIE83868.1 - 4.6e-05 23.4 8.9 1.3 9.2 0.2 4.4 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-BED PF02892.10 EIE83868.1 - 0.0018 18.0 6.3 0.31 10.8 0.1 3.5 2 1 1 3 3 3 1 BED zinc finger PyrI_C PF02748.10 EIE83868.1 - 0.02 14.2 1.1 1.3 8.4 0.0 2.7 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_6 PF13912.1 EIE83868.1 - 0.021 14.6 7.9 2.8 7.9 0.1 3.9 4 0 0 4 4 3 0 C2H2-type zinc finger zf-C2HC_2 PF13913.1 EIE83868.1 - 0.075 12.7 15.9 0.13 11.9 0.9 3.2 3 1 0 3 3 3 0 zinc-finger of a C2HC-type LIM PF00412.17 EIE83868.1 - 0.076 13.1 3.6 0.15 12.1 2.2 1.7 1 1 1 2 2 2 0 LIM domain Zn_Tnp_IS1595 PF12760.2 EIE83868.1 - 0.082 12.7 7.3 0.37 10.6 1.8 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-C2H2_2 PF12756.2 EIE83868.1 - 0.14 12.3 0.5 0.14 12.3 0.3 2.8 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-CHY PF05495.7 EIE83868.1 - 0.15 12.2 5.9 0.17 12.0 3.2 1.6 1 1 0 1 1 1 0 CHY zinc finger IBR PF01485.16 EIE83868.1 - 0.18 11.6 9.1 0.12 12.2 4.1 2.3 1 1 1 2 2 2 0 IBR domain Zn-ribbon_8 PF09723.5 EIE83868.1 - 0.24 11.3 6.5 8.3 6.4 0.0 3.2 2 1 1 3 3 3 0 Zinc ribbon domain zf-AN1 PF01428.11 EIE83868.1 - 0.38 10.6 10.4 1.1 9.1 1.8 2.8 1 1 1 2 2 2 0 AN1-like Zinc finger zf-Di19 PF05605.7 EIE83868.1 - 1.6 8.9 7.7 6.6 6.9 0.0 2.8 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Dehydrin PF00257.14 EIE83869.1 - 0.04 14.2 0.5 0.047 14.0 0.4 1.1 1 0 0 1 1 1 0 Dehydrin PPR_2 PF13041.1 EIE83870.1 - 6.9e-41 138.0 4.9 4.9e-07 29.6 0.0 8.8 3 3 7 10 10 10 8 PPR repeat family PPR_3 PF13812.1 EIE83870.1 - 3.7e-29 98.5 0.8 0.00016 21.7 0.0 10.8 11 1 1 12 12 12 6 Pentatricopeptide repeat domain PPR PF01535.15 EIE83870.1 - 8.2e-17 59.9 13.4 0.11 12.4 0.0 10.7 11 2 0 11 11 11 6 PPR repeat PPR_1 PF12854.2 EIE83870.1 - 1.8e-11 43.2 6.4 1.7 8.2 0.0 8.8 8 1 0 8 8 8 4 PPR repeat ECSIT PF06239.6 EIE83870.1 - 6.3e-08 31.7 1.6 0.0097 14.7 0.0 5.6 3 2 3 6 6 6 2 Evolutionarily conserved signalling intermediate in Toll pathway YodL PF14191.1 EIE83870.1 - 0.0024 18.3 1.7 16 6.0 0.0 4.8 3 2 1 5 5 5 1 YodL-like HTH_Crp_2 PF13545.1 EIE83870.1 - 0.027 14.2 0.0 0.074 12.8 0.0 1.7 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain SWIB PF02201.13 EIE83871.1 - 1.2e-24 85.7 0.1 1.2e-24 85.7 0.1 2.8 3 0 0 3 3 3 1 SWIB/MDM2 domain DctQ PF04290.7 EIE83872.1 - 0.24 11.1 6.4 0.16 11.7 0.6 2.2 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component Ribosomal_L6 PF00347.18 EIE83873.1 - 1.1e-29 102.7 7.9 2e-17 63.4 2.6 2.0 2 0 0 2 2 2 2 Ribosomal protein L6 Pkinase PF00069.20 EIE83874.1 - 9e-63 211.8 0.0 1e-62 211.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE83874.1 - 5.1e-33 114.2 0.0 6.8e-33 113.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE83874.1 - 5.6e-08 32.0 0.0 9.5e-08 31.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like DUF2481 PF10654.4 EIE83874.1 - 0.049 13.3 0.1 0.096 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2481) Myb_DNA-bind_4 PF13837.1 EIE83876.1 - 6.3e-12 45.4 1.2 6.3e-12 45.4 0.8 1.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 EIE83876.1 - 4.4e-07 29.6 0.2 1.1e-06 28.4 0.2 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EIE83876.1 - 5e-05 23.3 0.3 0.00013 21.9 0.2 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EIE83876.1 - 0.00079 19.4 0.2 0.0017 18.3 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_3 PF12776.2 EIE83876.1 - 0.0073 16.9 1.0 0.0073 16.9 0.7 1.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.4 EIE83876.1 - 0.18 12.0 4.9 0.62 10.2 0.6 2.8 2 1 1 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like LIM PF00412.17 EIE83877.1 - 1.4e-18 66.7 83.8 1.5e-08 34.5 6.2 6.6 6 1 0 6 6 6 4 LIM domain RdRP PF05183.7 EIE83878.1 - 6.9e-125 417.9 0.1 1.1e-124 417.3 0.1 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase CENP-K PF11802.3 EIE83879.1 - 9.5e-16 57.8 15.5 4.2e-15 55.7 10.7 2.2 1 1 0 1 1 1 1 Centromere-associated protein K AvrB_AvrC PF05394.6 EIE83879.1 - 0.027 13.4 2.9 0.039 12.9 2.0 1.2 1 0 0 1 1 1 0 Avirulence protein ADIP PF11559.3 EIE83879.1 - 3.6 7.4 14.4 2.1 8.2 0.8 2.6 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding Fib_alpha PF08702.5 EIE83879.1 - 4.1 7.5 12.5 0.9 9.6 4.1 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family A_deaminase PF00962.17 EIE83880.1 - 1.4e-114 382.5 0.1 2.1e-114 381.8 0.1 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase PGAP1 PF07819.8 EIE83881.1 - 6.4e-07 29.1 0.0 1.1e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 EIE83881.1 - 2.7e-05 24.1 0.0 3.8e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIE83881.1 - 5e-05 22.9 0.0 6.1e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIE83881.1 - 0.00023 20.9 0.0 0.00038 20.2 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 EIE83881.1 - 0.00026 20.3 0.0 0.00049 19.4 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) LCAT PF02450.10 EIE83881.1 - 0.0021 17.0 0.1 0.0066 15.4 0.0 1.8 3 0 0 3 3 3 1 Lecithin:cholesterol acyltransferase DUF915 PF06028.6 EIE83881.1 - 0.014 14.5 0.0 0.24 10.4 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) RhoGAP PF00620.22 EIE83882.1 - 1.2e-48 164.6 0.2 1.2e-48 164.6 0.2 2.4 3 0 0 3 3 3 1 RhoGAP domain C1_1 PF00130.17 EIE83882.1 - 2e-09 37.0 1.7 2e-09 37.0 1.2 2.8 3 0 0 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) LIM PF00412.17 EIE83882.1 - 3.3e-07 30.2 4.2 3.3e-07 30.2 2.9 2.8 3 0 0 3 3 3 1 LIM domain ATP-cone PF03477.11 EIE83882.1 - 0.034 14.5 1.9 0.61 10.5 0.5 2.8 2 1 0 2 2 2 0 ATP cone domain DUF948 PF06103.6 EIE83882.1 - 0.28 11.0 4.6 1.6 8.6 0.4 2.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) V_ATPase_I PF01496.14 EIE83882.1 - 0.95 7.2 7.7 1.5 6.5 5.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family WD40 PF00400.27 EIE83883.1 - 2.1e-05 24.2 2.8 4.1 7.4 0.2 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat PQQ_2 PF13360.1 EIE83883.1 - 0.082 12.3 0.0 0.16 11.3 0.0 1.6 1 1 0 1 1 1 0 PQQ-like domain Atg14 PF10186.4 EIE83884.1 - 0.00089 18.2 9.7 0.00089 18.2 6.7 1.7 2 0 0 2 2 2 1 UV radiation resistance protein and autophagy-related subunit 14 DUF3584 PF12128.3 EIE83884.1 - 0.024 12.0 11.4 0.04 11.2 7.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Spc7 PF08317.6 EIE83884.1 - 1 7.9 18.8 1.2 7.7 9.5 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein ARD PF03079.9 EIE83884.1 - 1.4 8.8 9.6 0.9 9.4 5.0 1.9 2 0 0 2 2 2 0 ARD/ARD' family DUF4407 PF14362.1 EIE83884.1 - 4.2 6.2 8.3 7.6 5.3 5.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MtrF PF09472.5 EIE83885.1 - 0.0081 15.3 1.5 0.022 13.9 1.0 1.7 1 0 0 1 1 1 1 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) DUF4112 PF13430.1 EIE83885.1 - 0.041 13.7 0.8 4.2 7.3 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4112) YtpI PF14007.1 EIE83885.1 - 0.31 10.9 8.8 0.27 11.2 2.1 2.4 2 0 0 2 2 2 0 YtpI-like protein DUF1211 PF06736.6 EIE83885.1 - 6.4 7.0 7.8 0.41 10.8 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1211) Ribosomal_L27 PF01016.14 EIE83886.1 - 7.2e-38 128.2 0.7 8.9e-38 127.9 0.5 1.1 1 0 0 1 1 1 1 Ribosomal L27 protein Med9 PF07544.8 EIE83887.1 - 2.1e-05 24.1 0.2 3e-05 23.6 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 Peptidase_C54 PF03416.14 EIE83888.1 - 5e-44 150.5 0.1 7e-44 150.0 0.1 1.2 1 0 0 1 1 1 1 Peptidase family C54 RNA_pol_Rpc34 PF05158.7 EIE83889.1 - 3.6e-69 233.4 1.8 9.5e-68 228.7 1.3 2.0 1 1 0 1 1 1 1 RNA polymerase Rpc34 subunit B-block_TFIIIC PF04182.7 EIE83889.1 - 0.0073 16.1 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC HTH_36 PF13730.1 EIE83889.1 - 0.0089 16.1 0.3 0.026 14.6 0.2 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain RPA_C PF08784.6 EIE83889.1 - 0.052 13.9 0.1 0.52 10.7 0.1 2.6 4 0 0 4 4 4 0 Replication protein A C terminal CMD PF02627.15 EIE83890.1 - 0.00011 21.9 0.0 0.0003 20.5 0.0 1.7 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family Phenol_monoox PF04663.7 EIE83890.1 - 0.081 12.6 0.1 0.21 11.3 0.0 1.7 2 0 0 2 2 2 0 Phenol hydroxylase conserved region HutP PF09021.6 EIE83890.1 - 0.12 12.6 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 HutP Rhomboid PF01694.17 EIE83892.1 - 1.3e-15 57.7 2.1 1.6e-15 57.3 1.5 1.2 1 0 0 1 1 1 1 Rhomboid family DUF1956 PF09209.6 EIE83893.1 - 0.14 12.0 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1956) Rad10 PF03834.9 EIE83894.1 - 6.4e-25 86.6 0.9 6.4e-25 86.6 0.7 1.6 2 0 0 2 2 2 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) DUF1566 PF07603.6 EIE83894.1 - 0.0057 16.3 2.4 0.008 15.9 1.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1566) Pkinase PF00069.20 EIE83895.1 - 3.6e-60 203.3 0.0 5.1e-60 202.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE83895.1 - 8.3e-31 106.9 0.0 1.2e-30 106.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EIE83895.1 - 7e-07 29.6 0.2 2.2e-06 28.0 0.1 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EIE83895.1 - 2.8e-06 26.5 0.0 5.7e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EIE83895.1 - 0.0012 18.5 0.2 0.041 13.6 0.2 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family CRT-like PF08627.5 EIE83896.1 - 0.76 9.7 4.8 2 8.3 3.3 1.9 1 1 0 1 1 1 0 CRT-like DUF2985 PF11204.3 EIE83896.1 - 1.9 8.2 8.2 0.65 9.7 2.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2985) SNAPc_SNAP43 PF09808.4 EIE83897.1 - 3.4e-05 23.6 2.8 3.4e-05 23.6 1.9 1.9 2 0 0 2 2 2 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 Ank_2 PF12796.2 EIE83898.1 - 4.3e-43 145.5 8.8 3.2e-12 46.6 0.0 4.4 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EIE83898.1 - 1.8e-24 85.6 6.4 4.1e-07 30.3 0.0 5.4 4 1 1 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.25 EIE83898.1 - 2.3e-22 77.6 13.4 1.5e-07 30.9 0.0 6.8 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.1 EIE83898.1 - 3.1e-16 59.0 9.9 8.7e-10 38.5 0.1 6.3 2 2 5 7 7 7 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIE83898.1 - 1.2e-15 56.0 5.3 0.001 19.0 0.0 8.1 8 0 0 8 8 8 4 Ankyrin repeat Pkinase PF00069.20 EIE83899.1 - 2.6e-74 249.6 0.1 3.5e-74 249.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE83899.1 - 2.1e-35 122.0 0.0 2.8e-35 121.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE83899.1 - 2e-06 26.9 0.0 2.7e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EIE83899.1 - 0.00093 18.3 0.0 0.0016 17.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIE83899.1 - 0.0028 17.4 0.0 0.018 14.8 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Beta-APP PF03494.8 EIE83900.1 - 0.14 11.6 4.6 0.27 10.7 3.2 1.5 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) Kelch_5 PF13854.1 EIE83901.1 - 2.1e-15 56.2 7.9 0.0014 18.5 0.1 5.5 5 1 0 5 5 5 4 Kelch motif Kelch_6 PF13964.1 EIE83901.1 - 1.5e-11 43.9 11.5 0.00041 20.3 0.0 5.4 4 1 1 5 5 5 3 Kelch motif Kelch_1 PF01344.20 EIE83901.1 - 2e-11 43.2 14.7 0.00024 20.5 0.5 5.5 5 1 0 5 5 5 3 Kelch motif Kelch_3 PF13415.1 EIE83901.1 - 8.1e-11 41.7 7.2 0.039 14.1 0.1 4.8 3 1 1 4 4 4 4 Galactose oxidase, central domain Kelch_4 PF13418.1 EIE83901.1 - 7.4e-07 28.8 15.4 0.037 13.7 0.1 5.9 4 2 1 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.10 EIE83901.1 - 0.00019 21.0 4.9 0.43 10.4 0.0 5.0 5 1 0 5 5 5 2 Kelch motif DUF4366 PF14283.1 EIE83901.1 - 0.026 13.9 0.0 0.049 13.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DEAD PF00270.24 EIE83902.1 - 1.2e-41 142.0 0.1 1.2e-41 142.0 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIE83902.1 - 2.5e-23 81.7 0.1 2.5e-23 81.7 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Synapsin_C PF02750.9 EIE83902.1 - 0.026 13.6 0.1 0.077 12.0 0.0 1.7 2 0 0 2 2 2 0 Synapsin, ATP binding domain ResIII PF04851.10 EIE83902.1 - 0.057 13.2 12.2 0.081 12.7 0.0 3.0 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit CMS1 PF14617.1 EIE83902.1 - 0.071 12.1 0.1 0.071 12.1 0.0 2.5 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit TFIIA PF03153.8 EIE83902.1 - 3.5 7.4 22.7 5.5 6.7 15.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GET2 PF08690.5 EIE83902.1 - 8.2 5.5 14.8 15 4.6 10.2 1.4 1 0 0 1 1 1 0 GET complex subunit GET2 PAT1 PF09770.4 EIE83902.1 - 8.2 4.5 33.2 12 3.9 23.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Retrotrans_gag PF03732.12 EIE83903.1 - 0.0048 16.9 0.0 0.0048 16.9 0.0 4.4 6 0 0 6 6 6 1 Retrotransposon gag protein RVP PF00077.15 EIE83903.1 - 0.0049 16.7 0.2 0.15 12.0 0.0 2.9 1 1 1 2 2 2 1 Retroviral aspartyl protease Peptidase_M3_N PF08439.5 EIE83903.1 - 0.072 13.1 3.2 0.11 12.5 0.2 2.9 3 0 0 3 3 3 0 Oligopeptidase F gag-asp_proteas PF13975.1 EIE83903.1 - 0.15 11.9 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVT_1 PF00078.22 EIE83904.1 - 5.5e-21 74.9 0.0 9.6e-21 74.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EIE83904.1 - 1.6e-15 56.7 0.0 4.5e-15 55.3 0.0 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EIE83904.1 - 0.00015 21.8 0.3 0.00034 20.6 0.0 1.7 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family DUF972 PF06156.8 EIE83905.1 - 3e-05 24.3 1.7 5.2e-05 23.5 1.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF972) TSC22 PF01166.13 EIE83905.1 - 0.00025 20.9 2.3 0.00056 19.8 1.6 1.5 1 0 0 1 1 1 1 TSC-22/dip/bun family DUF904 PF06005.7 EIE83905.1 - 0.015 15.5 2.5 0.027 14.7 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DUF2216 PF10226.4 EIE83905.1 - 0.051 13.0 0.1 0.085 12.3 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved proteins (DUF2216) bZIP_1 PF00170.16 EIE83905.1 - 0.081 12.8 3.2 0.17 11.8 2.2 1.5 1 0 0 1 1 1 0 bZIP transcription factor DivIC PF04977.10 EIE83905.1 - 0.22 10.9 1.6 0.44 10.0 1.1 1.4 1 0 0 1 1 1 0 Septum formation initiator rve PF00665.21 EIE83907.1 - 1e-21 77.2 0.0 2.3e-21 76.1 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE83907.1 - 1.4e-15 57.2 0.1 2.8e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.12 EIE83907.1 - 8.2e-09 35.4 0.1 2.3e-08 34.0 0.1 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein Chromo PF00385.19 EIE83907.1 - 4.2e-08 32.7 0.1 9.7e-08 31.5 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 EIE83907.1 - 0.00047 19.5 1.6 0.0015 17.9 1.1 2.0 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger UBN2 PF14223.1 EIE83907.1 - 0.13 12.0 0.0 0.36 10.6 0.0 1.8 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type bZIP_1 PF00170.16 EIE83908.1 - 0.03 14.2 0.7 0.045 13.7 0.5 1.3 1 0 0 1 1 1 0 bZIP transcription factor HALZ PF02183.13 EIE83908.1 - 0.045 13.4 1.8 0.067 12.9 1.2 1.3 1 0 0 1 1 1 0 Homeobox associated leucine zipper Vezatin PF12632.2 EIE83908.1 - 0.054 12.5 0.2 0.085 11.9 0.2 1.3 1 0 0 1 1 1 0 Mysoin-binding motif of peroxisomes CENP-Q PF13094.1 EIE83908.1 - 1.4 8.9 6.7 2.2 8.3 4.7 1.4 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF3417 PF11897.3 EIE83910.1 - 0.21 11.5 1.6 0.23 11.4 1.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3417) DUF2407_C PF13373.1 EIE83910.1 - 2 8.3 4.8 2.1 8.2 3.3 1.1 1 0 0 1 1 1 0 DUF2407 C-terminal domain DUF2457 PF10446.4 EIE83910.1 - 6.2 5.4 12.7 7 5.2 8.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF1759 PF03564.10 EIE83911.1 - 0.0011 18.7 0.2 0.0014 18.4 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) Retrotrans_gag PF03732.12 EIE83911.1 - 0.0059 16.6 0.0 0.015 15.3 0.0 1.7 2 0 0 2 2 2 1 Retrotransposon gag protein BRX PF08381.6 EIE83911.1 - 0.022 13.8 0.5 0.046 12.7 0.3 1.5 1 0 0 1 1 1 0 Transcription factor regulating root and shoot growth via Pin3 Phage_integrase PF00589.17 EIE83912.1 - 7.4e-07 28.9 0.2 4.7e-06 26.3 0.0 2.3 3 0 0 3 3 3 1 Phage integrase family DUF3071 PF11268.3 EIE83912.1 - 0.0047 16.6 0.1 0.016 14.9 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3071) Phage_int_SAM_1 PF02899.12 EIE83912.1 - 0.0057 16.7 0.0 0.027 14.6 0.0 2.2 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain DUF1397 PF07165.6 EIE83913.1 - 0.074 12.2 0.5 0.17 11.0 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1397) tRNA-synt_1 PF00133.17 EIE83914.1 - 0.00068 17.7 0.0 0.00077 17.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) DUF2577 PF10844.3 EIE83915.1 - 0.0032 17.4 0.0 0.0046 16.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2577) CTNNB1_binding PF08347.6 EIE83915.1 - 0.03 14.5 0.0 0.038 14.2 0.0 1.1 1 0 0 1 1 1 0 N-terminal CTNNB1 binding Nsp1_C PF05064.8 EIE83916.1 - 4.2e-35 119.9 8.9 4.2e-35 119.9 6.2 1.7 2 0 0 2 2 2 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.1 EIE83916.1 - 0.1 12.8 149.4 0.11 12.7 30.4 4.3 2 1 2 4 4 4 0 Nucleoporin FG repeat region Tropomyosin PF00261.15 EIE83916.1 - 0.14 11.2 6.7 0.21 10.6 4.6 1.2 1 0 0 1 1 1 0 Tropomyosin HR1 PF02185.11 EIE83916.1 - 0.16 11.7 11.2 0.84 9.4 0.9 3.1 2 1 2 4 4 4 0 Hr1 repeat IncA PF04156.9 EIE83916.1 - 0.33 10.5 14.5 17 4.9 10.1 2.3 1 1 0 1 1 1 0 IncA protein BLOC1_2 PF10046.4 EIE83916.1 - 0.39 10.8 12.4 0.39 10.8 3.3 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Phage_GP20 PF06810.6 EIE83916.1 - 0.58 9.5 16.8 0.37 10.2 7.4 2.6 1 1 0 2 2 2 0 Phage minor structural protein GP20 EMP24_GP25L PF01105.19 EIE83916.1 - 2.9 7.5 9.5 2.4 7.8 2.0 2.4 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD CENP-Q PF13094.1 EIE83916.1 - 8 6.4 13.4 35 4.3 9.3 1.9 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Mod_r PF07200.8 EIE83916.1 - 8.9 6.2 15.1 4.3 7.2 0.2 2.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein BSP_II PF05432.6 EIE83918.1 - 0.069 12.4 8.4 0.07 12.3 3.3 2.2 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Nucleoplasmin PF03066.10 EIE83918.1 - 0.07 12.6 8.0 0.096 12.2 2.8 2.5 2 0 0 2 2 2 0 Nucleoplasmin DUF4407 PF14362.1 EIE83918.1 - 5.3 5.9 17.2 11 4.8 11.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Methyltrn_RNA_3 PF02598.12 EIE83921.1 - 1.4e-68 231.4 0.0 2.7e-68 230.4 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methyltransferase Lactonase PF10282.4 EIE83922.1 - 1.7e-107 359.5 0.0 1.9e-107 359.3 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller YmzC PF14157.1 EIE83922.1 - 0.00028 20.6 0.6 4 7.3 0.0 4.3 4 0 0 4 4 4 2 YmzC-like protein DUF1513 PF07433.6 EIE83922.1 - 0.016 14.1 0.0 0.29 10.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1513) SWIB PF02201.13 EIE83923.1 - 6.4e-18 64.2 0.2 1.2e-17 63.3 0.2 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain Ribosomal_60s PF00428.14 EIE83924.1 - 1.4e-26 92.6 9.6 1.7e-26 92.4 6.7 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Glutaredoxin PF00462.19 EIE83925.1 - 3.1e-12 46.2 0.1 6.1e-12 45.3 0.0 1.5 1 1 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.1 EIE83925.1 - 0.027 14.6 0.0 0.092 12.9 0.0 1.9 2 1 1 3 3 3 0 Glutathione S-transferase, N-terminal domain NADH_u_ox_C PF12853.2 EIE83925.1 - 0.046 13.4 0.1 0.085 12.5 0.1 1.6 1 1 0 1 1 1 0 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit Phos_pyr_kin PF08543.7 EIE83926.1 - 7.9e-19 67.8 0.0 2e-18 66.5 0.0 1.7 1 1 1 2 2 2 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 EIE83926.1 - 2.9e-12 46.3 0.0 5.6e-12 45.4 0.0 1.4 1 1 0 1 1 1 1 pfkB family carbohydrate kinase YfdX PF10938.3 EIE83926.1 - 0.053 13.1 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 YfdX protein DEAD PF00270.24 EIE83927.1 - 1.4e-47 161.3 0.0 1.5e-46 157.9 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIE83927.1 - 2.6e-25 88.0 0.0 6.8e-25 86.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 EIE83927.1 - 0.012 15.4 0.6 0.23 11.2 0.1 2.7 2 0 0 2 2 2 0 Part of AAA domain SnoaL PF07366.7 EIE83928.1 - 0.0043 16.6 0.0 0.011 15.3 0.0 1.6 2 0 0 2 2 2 1 SnoaL-like polyketide cyclase NTF2 PF02136.15 EIE83928.1 - 0.066 13.5 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain DUF3729 PF12526.3 EIE83928.1 - 4.5 8.6 7.5 5.4 8.3 4.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3729) TPR_MLP1_2 PF07926.7 EIE83929.1 - 0.0063 16.2 1.3 0.014 15.1 0.9 1.6 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein Pox_A_type_inc PF04508.7 EIE83929.1 - 0.62 10.0 0.1 0.62 10.0 0.1 2.8 3 1 0 3 3 3 0 Viral A-type inclusion protein repeat OEP PF02321.13 EIE83929.1 - 2.1 7.9 9.6 0.44 10.1 0.2 2.7 3 0 0 3 3 3 0 Outer membrane efflux protein YlqD PF11068.3 EIE83929.1 - 8.3 6.4 11.2 7.7 6.5 5.6 2.3 2 1 0 2 2 2 0 YlqD protein RVT_1 PF00078.22 EIE83930.1 - 5.5e-22 78.1 0.1 1.1e-21 77.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.1 EIE83932.1 - 0.00029 21.0 1.4 0.00029 21.0 1.0 2.2 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase OrfB_Zn_ribbon PF07282.6 EIE83932.1 - 0.088 12.4 0.2 0.16 11.6 0.2 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain DUF3439 PF11921.3 EIE83933.1 - 5.5e-05 22.8 0.7 9.6e-05 22.1 0.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) SSP160 PF06933.6 EIE83933.1 - 2.4 6.0 9.3 3 5.7 6.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 ATP-synt_G PF04718.10 EIE83934.1 - 1.8e-21 76.6 0.4 2.7e-21 76.1 0.3 1.3 1 0 0 1 1 1 1 Mitochondrial ATP synthase g subunit DUF4346 PF14251.1 EIE83936.1 - 0.025 14.3 0.2 0.03 14.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4346) Chitin_synth_1 PF01644.12 EIE83936.1 - 0.044 13.5 0.1 0.048 13.4 0.1 1.1 1 0 0 1 1 1 0 Chitin synthase polyprenyl_synt PF00348.12 EIE83936.1 - 0.057 12.2 1.3 0.066 12.0 0.9 1.1 1 0 0 1 1 1 0 Polyprenyl synthetase Glyco_transf_15 PF01793.11 EIE83937.1 - 3.1e-18 65.8 0.6 3.4e-18 65.6 0.4 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Beta_elim_lyase PF01212.16 EIE83938.1 - 4.9e-73 245.7 0.1 6.4e-73 245.4 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EIE83938.1 - 0.00034 19.7 0.1 0.0044 16.1 0.0 2.1 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 EIE83938.1 - 0.00091 17.6 0.0 0.0022 16.3 0.0 1.5 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Ala_racemase_N PF01168.15 EIE83938.1 - 0.0079 15.7 0.6 0.11 12.0 0.0 2.2 2 0 0 2 2 2 1 Alanine racemase, N-terminal domain zf-CCCH_2 PF14608.1 EIE83939.1 - 6.3e-10 38.6 50.0 9.1e-05 22.3 5.2 5.7 5 1 0 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type SSFA2_C PF14723.1 EIE83940.1 - 0.067 12.9 0.1 0.074 12.7 0.1 1.1 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus DDE_3 PF13358.1 EIE83942.1 - 8.2e-24 84.0 0.5 1.7e-18 66.7 0.1 2.3 1 1 1 2 2 2 2 DDE superfamily endonuclease DDE_1 PF03184.14 EIE83942.1 - 0.008 15.3 0.2 0.013 14.6 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Ins_P5_2-kin PF06090.7 EIE83943.1 - 0.034 13.1 0.1 0.035 13.1 0.1 1.1 1 0 0 1 1 1 0 Inositol-pentakisphosphate 2-kinase HTH_Tnp_Tc3_2 PF01498.13 EIE83944.1 - 0.00046 20.1 3.1 0.0011 19.0 2.2 1.6 1 0 0 1 1 1 1 Transposase rve PF00665.21 EIE83945.1 - 8e-18 64.6 0.0 3.6e-17 62.5 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 EIE83945.1 - 1.9e-14 53.5 0.7 5.1e-14 52.1 0.5 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE83945.1 - 1.4e-06 27.9 1.3 5.4e-06 25.9 0.7 2.2 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.1 EIE83945.1 - 0.00021 21.7 0.1 0.0023 18.4 0.0 2.4 2 0 0 2 2 2 1 Aspartyl protease Tudor-knot PF11717.3 EIE83945.1 - 0.019 14.6 0.7 0.052 13.2 0.5 1.8 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain YcgR_2 PF12945.2 EIE83945.1 - 0.027 14.3 0.0 0.4 10.5 0.0 2.5 2 0 0 2 2 2 0 Flagellar protein YcgR gag-asp_proteas PF13975.1 EIE83945.1 - 0.067 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF4363 PF14276.1 EIE83946.1 - 0.011 15.4 1.5 0.012 15.2 0.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) LUC7 PF03194.10 EIE83946.1 - 0.069 12.6 6.0 0.036 13.5 2.5 1.5 1 1 0 2 2 2 0 LUC7 N_terminus CLTH PF10607.4 EIE83946.1 - 0.32 10.6 2.4 0.43 10.2 1.5 1.5 1 1 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain eIF3_N PF09440.5 EIE83946.1 - 0.48 10.5 3.6 1.1 9.4 1.1 2.3 1 1 2 3 3 3 0 eIF3 subunit 6 N terminal domain MRL1 PF13003.2 EIE83947.1 - 0.11 12.2 0.1 0.14 12.0 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L1 DDE_3 PF13358.1 EIE83948.1 - 5e-17 62.0 0.0 7.2e-17 61.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE83948.1 - 1.6e-09 37.6 2.6 5e-09 36.0 0.9 2.2 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.1 EIE83948.1 - 7e-05 22.3 0.0 0.00018 21.0 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_7 PF02796.10 EIE83948.1 - 0.00012 21.8 0.5 0.00062 19.5 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_11 PF08279.7 EIE83948.1 - 0.00051 19.6 0.0 0.0014 18.2 0.0 1.7 1 0 0 1 1 1 1 HTH domain HTH_17 PF12728.2 EIE83948.1 - 0.0017 18.5 0.0 0.0037 17.4 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.1 EIE83948.1 - 0.0019 18.3 0.1 0.012 15.7 0.0 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.1 EIE83948.1 - 0.0019 18.9 0.7 1.7 9.4 0.0 2.9 2 0 0 2 2 2 1 Homeodomain-like domain HTH_22 PF13309.1 EIE83948.1 - 0.0029 17.3 0.1 0.0056 16.4 0.0 1.4 1 0 0 1 1 1 1 HTH domain HTH_38 PF13936.1 EIE83948.1 - 0.0036 16.8 0.0 0.0078 15.7 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_IclR PF09339.5 EIE83948.1 - 0.0037 16.8 0.0 0.0072 15.8 0.0 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_36 PF13730.1 EIE83948.1 - 0.0091 16.1 0.5 0.25 11.4 0.0 2.9 3 0 0 3 3 3 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.7 EIE83948.1 - 0.011 15.1 0.0 0.03 13.7 0.0 1.7 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_28 PF13518.1 EIE83948.1 - 0.014 15.4 0.0 0.034 14.1 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain UPF0122 PF04297.9 EIE83948.1 - 0.019 14.9 0.4 0.062 13.3 0.1 1.9 2 0 0 2 2 2 0 Putative helix-turn-helix protein, YlxM / p13 like HTH_Tnp_4 PF13613.1 EIE83948.1 - 0.045 13.3 0.0 0.69 9.5 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix of DDE superfamily endonuclease HTH_AsnC-type PF13404.1 EIE83948.1 - 0.055 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Terminase_5 PF06056.7 EIE83948.1 - 0.059 12.9 0.1 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) TetR_N PF00440.18 EIE83948.1 - 0.074 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family HTH_30 PF13556.1 EIE83948.1 - 0.098 12.2 0.0 0.25 10.9 0.0 1.6 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain HTH_6 PF01418.12 EIE83948.1 - 0.15 11.8 0.0 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family rve PF00665.21 EIE83950.1 - 8e-18 64.6 0.0 3.6e-17 62.5 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 EIE83950.1 - 1.9e-14 53.5 0.7 5.1e-14 52.1 0.5 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE83950.1 - 1.4e-06 27.9 1.3 5.4e-06 25.9 0.7 2.2 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.1 EIE83950.1 - 0.00021 21.7 0.1 0.0023 18.4 0.0 2.4 2 0 0 2 2 2 1 Aspartyl protease Tudor-knot PF11717.3 EIE83950.1 - 0.019 14.6 0.7 0.052 13.2 0.5 1.8 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain YcgR_2 PF12945.2 EIE83950.1 - 0.027 14.3 0.0 0.4 10.5 0.0 2.5 2 0 0 2 2 2 0 Flagellar protein YcgR gag-asp_proteas PF13975.1 EIE83950.1 - 0.067 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Zn_Tnp_IS1 PF03811.8 EIE83951.1 - 0.00046 19.6 6.1 0.00089 18.6 4.3 1.5 1 0 0 1 1 1 1 InsA N-terminal domain Herpes_BLRF2 PF05812.7 EIE83951.1 - 0.0089 15.8 0.4 5.3 6.8 0.1 2.5 2 0 0 2 2 2 2 Herpesvirus BLRF2 protein Macoilin PF09726.4 EIE83951.1 - 0.032 12.5 0.1 0.044 12.0 0.1 1.3 1 0 0 1 1 1 0 Transmembrane protein Cytochrome_C7 PF14522.1 EIE83951.1 - 0.035 13.7 1.7 0.078 12.6 1.2 1.5 1 0 0 1 1 1 0 Cytochrome c7 Cytochrom_c3_2 PF14537.1 EIE83951.1 - 0.13 12.6 2.5 0.34 11.2 1.8 1.7 1 0 0 1 1 1 0 Cytochrome c3 Nudix_N_2 PF14803.1 EIE83951.1 - 0.51 10.0 2.9 2.1 8.1 2.0 2.1 1 1 0 1 1 1 0 Nudix N-terminal Cytochrome_C554 PF13435.1 EIE83951.1 - 1.2 9.1 6.5 0.12 12.4 1.2 1.7 2 0 0 2 2 2 0 Cytochrome c554 and c-prime HTH_Tnp_Tc3_2 PF01498.13 EIE83952.1 - 6.4e-19 67.7 0.7 6.4e-19 67.7 0.5 2.9 3 1 1 4 4 4 1 Transposase DDE_3 PF13358.1 EIE83952.1 - 2.5e-08 33.7 1.0 2.4e-07 30.5 0.1 2.3 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_29 PF13551.1 EIE83952.1 - 1.7e-06 28.1 1.8 6.1e-06 26.3 0.9 2.1 2 1 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.1 EIE83952.1 - 2.5e-05 24.9 5.9 0.00058 20.5 0.2 3.8 3 1 1 4 4 4 1 Homeodomain-like domain HTH_23 PF13384.1 EIE83952.1 - 0.0009 18.8 0.8 0.061 13.0 0.0 3.4 3 0 0 3 3 3 1 Homeodomain-like domain HTH_21 PF13276.1 EIE83952.1 - 0.0096 15.9 0.3 0.62 10.1 0.0 2.9 2 1 1 3 3 3 1 HTH-like domain DUF3427 PF11907.3 EIE83952.1 - 0.072 12.0 0.3 0.12 11.2 0.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3427) DDE_3 PF13358.1 EIE83953.1 - 5.4e-14 52.1 0.0 1.1e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease NUDIX_4 PF14815.1 EIE83953.1 - 0.013 14.9 0.5 0.02 14.3 0.3 1.3 1 0 0 1 1 1 0 NUDIX domain RVT_1 PF00078.22 EIE83954.1 - 4.1e-06 26.3 0.1 6.4e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HTH_Tnp_Tc3_2 PF01498.13 EIE83955.1 - 1.1e-10 41.4 2.3 1.8e-10 40.7 0.9 1.8 2 0 0 2 2 2 1 Transposase HTH_Tnp_4 PF13613.1 EIE83955.1 - 0.014 14.9 0.0 0.029 13.9 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_23 PF13384.1 EIE83955.1 - 0.046 13.3 0.0 0.13 11.9 0.0 1.8 1 0 0 1 1 1 0 Homeodomain-like domain DDE_3 PF13358.1 EIE83956.1 - 3.8e-19 68.8 0.1 7.1e-19 68.0 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE83956.1 - 7.3e-15 54.7 1.8 3e-14 52.8 0.2 2.6 3 0 0 3 3 3 1 Transposase HTH_29 PF13551.1 EIE83956.1 - 5.8e-07 29.6 1.3 9.6e-07 28.9 0.1 2.0 2 0 0 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.1 EIE83956.1 - 1.1e-05 24.8 0.0 0.00022 20.7 0.0 2.6 2 0 0 2 2 2 1 Homeodomain-like domain HTH_38 PF13936.1 EIE83956.1 - 1.7e-05 24.2 0.0 3.9e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_32 PF13565.1 EIE83956.1 - 2.1e-05 25.2 3.6 0.0043 17.8 0.1 3.9 3 1 1 4 4 4 1 Homeodomain-like domain HTH_7 PF02796.10 EIE83956.1 - 0.00011 22.0 2.7 0.0017 18.1 0.2 2.7 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase HTH_28 PF13518.1 EIE83956.1 - 0.00011 22.1 0.0 0.00053 19.9 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_21 PF13276.1 EIE83956.1 - 0.00031 20.6 0.1 0.1 12.6 0.0 3.0 3 0 0 3 3 3 1 HTH-like domain Sigma70_r4_2 PF08281.7 EIE83956.1 - 0.00094 18.5 0.3 0.0099 15.3 0.0 2.7 3 0 0 3 3 3 1 Sigma-70, region 4 LacI PF00356.16 EIE83956.1 - 0.0089 15.6 0.9 1.7 8.3 0.1 2.7 3 0 0 3 3 2 1 Bacterial regulatory proteins, lacI family HTH_17 PF12728.2 EIE83956.1 - 0.01 16.0 1.4 1.1 9.5 0.1 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain rve PF00665.21 EIE83956.1 - 0.028 14.5 0.0 0.081 13.0 0.0 1.9 2 1 0 2 2 2 0 Integrase core domain CPSase_L_D3 PF02787.14 EIE83956.1 - 0.032 13.9 0.0 0.092 12.5 0.0 1.7 2 0 0 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain HTH_Tnp_4 PF13613.1 EIE83956.1 - 0.051 13.1 0.3 0.12 11.9 0.0 1.7 2 0 0 2 2 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_Tnp_ISL3 PF13542.1 EIE83956.1 - 0.53 9.5 2.7 17 4.6 0.1 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 HTH_Tnp_Tc3_2 PF01498.13 EIE83957.1 - 2.6e-07 30.5 1.9 4.9e-07 29.7 1.0 1.7 1 1 1 2 2 2 1 Transposase DDE_3 PF13358.1 EIE83957.1 - 0.019 14.7 0.0 0.062 13.0 0.0 1.8 2 0 0 2 2 2 0 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE83958.1 - 2.4e-19 69.1 2.5 2.8e-19 68.9 0.4 2.1 3 0 0 3 3 3 1 Transposase HTH_29 PF13551.1 EIE83958.1 - 2.8e-07 30.6 0.4 6.4e-07 29.5 0.3 1.6 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EIE83958.1 - 0.00028 20.4 1.1 0.0048 16.5 0.0 3.0 3 0 0 3 3 3 1 Homeodomain-like domain HTH_32 PF13565.1 EIE83958.1 - 0.00036 21.2 3.4 0.0012 19.5 0.4 3.1 3 1 1 4 4 4 1 Homeodomain-like domain DDE_3 PF13358.1 EIE83958.1 - 0.00074 19.2 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_28 PF13518.1 EIE83958.1 - 0.0086 16.0 0.1 0.032 14.2 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_40 PF14493.1 EIE83958.1 - 0.12 12.6 0.2 0.84 9.8 0.0 2.4 3 0 0 3 3 3 0 Helix-turn-helix domain LacI PF00356.16 EIE83958.1 - 6.4 6.4 5.6 8.1 6.1 0.0 3.0 4 0 0 4 4 4 0 Bacterial regulatory proteins, lacI family rve PF00665.21 EIE83960.1 - 4.4e-19 68.7 0.0 1.1e-18 67.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE83960.1 - 3.1e-16 59.3 0.5 8.8e-16 57.9 0.1 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE83960.1 - 1.3e-13 50.4 1.8 3.5e-13 49.0 1.3 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RNase_H PF00075.19 EIE83960.1 - 0.041 14.2 0.0 0.12 12.7 0.0 1.8 1 0 0 1 1 1 0 RNase H zf-CCHC PF00098.18 EIE83961.1 - 5.1e-07 29.3 9.0 0.0003 20.5 0.4 2.3 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 EIE83961.1 - 0.00017 21.2 2.1 0.064 12.9 0.1 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.1 EIE83961.1 - 0.00087 18.7 4.4 0.0064 15.9 0.7 2.3 1 1 1 2 2 2 1 Zinc knuckle RRM_6 PF14259.1 EIE83961.1 - 0.035 14.0 0.0 0.064 13.2 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EIE83961.1 - 0.066 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cmc1 PF08583.5 EIE83961.1 - 0.22 11.3 3.3 0.38 10.5 2.3 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Zn_ribbon_2 PF12674.2 EIE83961.1 - 0.27 11.6 2.5 0.86 9.9 1.6 1.8 1 1 1 2 2 2 0 Putative zinc ribbon domain zf-CCHC_6 PF15288.1 EIE83961.1 - 0.32 10.6 12.3 1.7 8.3 1.5 3.0 2 1 1 3 3 3 0 Zinc knuckle DnaJ_CXXCXGXG PF00684.14 EIE83961.1 - 0.57 10.2 4.7 2.2 8.4 3.3 1.8 1 1 0 1 1 1 0 DnaJ central domain Actin PF00022.14 EIE83964.1 - 1.6e-17 63.0 0.0 3.6e-13 48.7 0.0 2.3 1 1 1 2 2 2 2 Actin HSP70 PF00012.15 EIE83965.1 - 5.1e-265 880.0 9.9 5.8e-265 879.8 6.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EIE83965.1 - 3e-16 58.9 0.2 2.4e-14 52.6 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Hydantoinase_A PF01968.13 EIE83965.1 - 0.0027 16.8 4.8 0.035 13.2 0.2 2.9 3 0 0 3 3 3 2 Hydantoinase/oxoprolinase DDR PF08841.5 EIE83965.1 - 0.008 15.0 0.9 0.028 13.2 0.3 1.9 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain AreA_N PF07573.6 EIE83965.1 - 0.074 13.6 0.1 0.29 11.7 0.0 2.1 2 0 0 2 2 2 0 Nitrogen regulatory protein AreA N terminus FtsA PF14450.1 EIE83965.1 - 0.084 12.7 6.4 1.5 8.6 0.5 4.0 2 2 0 2 2 2 0 Cell division protein FtsA HALZ PF02183.13 EIE83966.1 - 0.015 15.0 17.3 0.099 12.3 0.9 4.1 3 1 1 4 4 4 0 Homeobox associated leucine zipper Shugoshin_N PF07558.6 EIE83966.1 - 0.019 14.6 6.4 0.096 12.4 0.2 3.1 2 1 0 2 2 2 0 Shugoshin N-terminal coiled-coil region DUF972 PF06156.8 EIE83966.1 - 0.022 15.0 2.5 0.022 15.0 1.8 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF972) DivIC PF04977.10 EIE83966.1 - 0.062 12.7 22.8 0.28 10.6 1.0 3.8 2 1 2 4 4 4 0 Septum formation initiator GAS PF13851.1 EIE83966.1 - 0.12 11.5 25.9 0.047 12.8 8.1 2.8 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding DUF1875 PF08961.5 EIE83966.1 - 0.86 8.8 15.6 0.055 12.7 0.7 3.3 1 1 2 4 4 4 0 Domain of unknown function (DUF1875) DUF904 PF06005.7 EIE83966.1 - 1.4 9.2 29.7 1.4 9.2 2.1 4.0 2 1 1 3 3 3 0 Protein of unknown function (DUF904) bZIP_2 PF07716.10 EIE83966.1 - 1.6 8.6 21.2 0.17 11.7 1.5 4.3 4 1 0 4 4 4 0 Basic region leucine zipper CCDC155 PF14662.1 EIE83966.1 - 5.8 6.4 25.5 1.9 8.0 14.4 2.4 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 ATG16 PF08614.6 EIE83966.1 - 5.9 6.6 26.1 0.64 9.8 4.8 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) RabGAP-TBC PF00566.13 EIE83967.1 - 0.039 13.4 0.0 0.096 12.1 0.0 1.6 1 0 0 1 1 1 0 Rab-GTPase-TBC domain V-ATPase_C PF03223.10 EIE83967.1 - 0.044 12.7 0.2 0.065 12.1 0.1 1.2 1 0 0 1 1 1 0 V-ATPase subunit C RebB PF11747.3 EIE83967.1 - 0.12 12.2 0.6 0.26 11.1 0.0 1.8 2 0 0 2 2 2 0 Killing trait zf-RVT PF13966.1 EIE83969.1 - 4.2e-06 26.9 1.0 4.2e-06 26.9 0.7 2.1 3 0 0 3 3 3 1 zinc-binding in reverse transcriptase Jnk-SapK_ap_N PF09744.4 EIE83970.1 - 0.0099 15.8 9.9 0.013 15.5 6.8 1.3 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 SDP_N PF12278.3 EIE83970.1 - 0.13 11.8 7.4 0.17 11.5 5.1 1.2 1 0 0 1 1 1 0 Sex determination protein N terminal WTX PF09422.5 EIE83970.1 - 0.15 10.9 12.5 0.19 10.6 8.6 1.1 1 0 0 1 1 1 0 WTX protein DUF572 PF04502.8 EIE83970.1 - 0.17 11.0 21.0 0.21 10.7 14.6 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) Ndc1_Nup PF09531.5 EIE83970.1 - 0.22 9.9 16.4 0.24 9.7 11.4 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Utp14 PF04615.8 EIE83970.1 - 0.54 8.3 24.7 0.64 8.1 17.1 1.0 1 0 0 1 1 1 0 Utp14 protein TFIIA PF03153.8 EIE83970.1 - 0.61 9.9 30.0 0.74 9.6 20.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SOBP PF15279.1 EIE83970.1 - 0.61 10.4 20.4 0.75 10.1 14.1 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein Neur_chan_memb PF02932.11 EIE83970.1 - 0.67 9.7 8.9 0.79 9.5 6.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PAT1 PF09770.4 EIE83970.1 - 1.3 7.1 35.0 1.5 6.9 24.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4175 PF13779.1 EIE83970.1 - 2.7 5.5 37.9 3.3 5.2 26.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Exonuc_VII_L PF02601.10 EIE83970.1 - 2.8 7.0 17.4 3.4 6.7 12.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Med15 PF09606.5 EIE83970.1 - 3.6 5.6 40.7 4.2 5.4 28.2 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Hid1 PF12722.2 EIE83970.1 - 4.3 4.8 25.0 5.3 4.5 17.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PMSI1 PF15322.1 EIE83970.1 - 4.8 6.1 16.7 6.3 5.7 11.6 1.1 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative NST1 PF13945.1 EIE83970.1 - 6.4 6.7 25.4 9.4 6.2 17.6 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator Macoilin PF09726.4 EIE83970.1 - 8.4 4.5 19.0 12 4.0 13.2 1.2 1 0 0 1 1 1 0 Transmembrane protein Mem_trans PF03547.13 EIE83970.1 - 8.8 4.5 8.4 12 4.0 5.8 1.3 1 0 0 1 1 1 0 Membrane transport protein DUF4045 PF13254.1 EIE83970.1 - 9.3 5.4 22.0 11 5.1 15.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Fungal_trans PF04082.13 EIE83972.1 - 9.2e-09 34.5 0.7 2.3e-08 33.2 0.5 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIE83972.1 - 0.013 15.4 5.4 0.029 14.2 3.7 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Thaumatin PF00314.12 EIE83973.1 - 1.7e-31 109.3 12.4 3.8e-15 55.9 5.5 2.9 1 1 1 2 2 2 2 Thaumatin family DUF1769 PF08588.5 EIE83973.1 - 0.046 13.6 0.0 0.092 12.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1769) Pkinase PF00069.20 EIE83974.1 - 8.7e-08 31.6 0.0 1.8e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE83974.1 - 0.00037 19.6 0.0 0.00068 18.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Transposase_31 PF04754.7 EIE83976.1 - 0.002 17.5 0.1 0.0028 17.0 0.0 1.4 1 1 0 1 1 1 1 Putative transposase, YhgA-like DUF2887 PF11103.3 EIE83976.1 - 0.0026 17.4 0.2 0.0053 16.3 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2887) Osmo_CC PF08946.5 EIE83977.1 - 0.028 14.4 1.2 0.8 9.7 0.2 2.5 2 0 0 2 2 2 0 Osmosensory transporter coiled coil Phi-29_GP4 PF05464.6 EIE83977.1 - 0.074 12.9 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 Phi-29-like late genes activator (early protein GP4) RVT_1 PF00078.22 EIE83978.1 - 3.7e-17 62.4 0.0 4.5e-17 62.1 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_3 PF13358.1 EIE83979.1 - 2.7e-11 43.3 0.1 3.3e-11 43.1 0.1 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Oxidored_FMN PF00724.15 EIE83981.1 - 2.7e-102 342.2 0.0 3e-102 342.1 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF3425 PF11905.3 EIE83982.1 - 2e-11 43.8 7.1 2e-11 43.8 5.0 3.7 3 1 0 3 3 3 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 EIE83982.1 - 1.8e-07 30.9 1.3 3.5e-07 30.0 0.9 1.4 1 0 0 1 1 1 1 bZIP transcription factor DUF940 PF06082.6 EIE83982.1 - 0.076 11.5 0.4 0.1 11.1 0.3 1.1 1 0 0 1 1 1 0 Bacterial putative lipoprotein (DUF940) Glyco_transf_5 PF08323.6 EIE83983.1 - 5.6e-13 48.9 0.9 5.6e-12 45.6 0.6 2.5 2 1 0 2 2 2 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.15 EIE83983.1 - 9.8e-06 25.0 0.0 1.9e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 IBR PF01485.16 EIE83984.1 - 1.3e-05 24.9 0.3 1.3e-05 24.9 0.2 1.7 2 0 0 2 2 2 1 IBR domain KRE9 PF05390.6 EIE83984.1 - 0.086 13.1 0.1 0.15 12.4 0.1 1.3 1 0 0 1 1 1 0 Yeast cell wall synthesis protein KRE9/KNH1 FYVE_2 PF02318.11 EIE83984.1 - 2.2 8.2 5.7 1.4 8.8 1.0 2.2 2 0 0 2 2 2 0 FYVE-type zinc finger zf-piccolo PF05715.8 EIE83984.1 - 2.6 8.1 10.3 0.093 12.7 1.7 2.5 2 1 0 2 2 2 0 Piccolo Zn-finger RRM_1 PF00076.17 EIE83985.1 - 4.9e-10 38.9 0.0 2.7e-08 33.3 0.0 3.1 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE83985.1 - 4.3e-07 29.8 0.0 5.9e-06 26.1 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Peptidase_S49_N PF08496.5 EIE83985.1 - 1.4 8.6 11.4 2.3 7.9 0.3 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF4414 PF14377.1 EIE83985.1 - 2.6 7.9 6.7 2.7 7.9 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4414) Sec62 PF03839.11 EIE83985.1 - 3.2 7.1 13.5 1 8.7 5.2 2.1 2 0 0 2 2 2 0 Translocation protein Sec62 PBP PF01161.15 EIE83986.1 - 8.2e-07 28.9 0.0 1.5e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Med29 PF11568.3 EIE83986.1 - 0.06 13.3 0.8 0.35 10.9 0.0 2.3 2 0 0 2 2 2 0 Mediator complex subunit 29 Rad60-SLD PF11976.3 EIE83987.1 - 4.2e-20 71.2 1.6 2.7e-16 59.0 0.2 2.9 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EIE83987.1 - 0.046 13.1 0.7 0.12 11.8 0.1 2.0 2 0 0 2 2 2 0 Ubiquitin family SRP14 PF02290.10 EIE83987.1 - 1 9.3 3.9 1 9.2 0.1 2.7 3 0 0 3 3 3 0 Signal recognition particle 14kD protein DUF2097 PF09870.4 EIE83988.1 - 0.046 13.8 0.0 0.05 13.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2097) RVT_1 PF00078.22 EIE83990.1 - 3.6e-15 55.8 1.7 9.5e-15 54.5 1.1 1.8 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) MCLC PF05934.6 EIE83990.1 - 0.15 10.3 0.0 0.21 9.8 0.0 1.2 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) Oxidored_FMN PF00724.15 EIE83992.1 - 1.3e-101 339.9 0.0 1.5e-101 339.8 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family HpcH_HpaI PF03328.9 EIE83993.1 - 4.8e-32 110.6 0.3 3.5e-31 107.7 0.2 1.9 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 EIE83993.1 - 5.4e-14 51.7 0.0 4.2e-13 48.8 0.0 1.9 2 0 0 2 2 2 1 C-C_Bond_Lyase of the TIM-Barrel fold PK PF00224.16 EIE83993.1 - 0.0045 15.6 1.0 0.0062 15.1 0.7 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain B12D PF06522.6 EIE83994.1 - 1.2e-15 56.9 0.0 1.6e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit Trp_DMAT PF11991.3 EIE83995.1 - 0.18 10.9 0.6 0.33 10.1 0.0 1.6 2 0 0 2 2 2 0 Tryptophan dimethylallyltransferase GerE PF00196.14 EIE83996.1 - 0.035 13.4 0.0 0.046 13.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family LtrA PF06772.6 EIE83997.1 - 5.2e-18 65.0 7.8 5e-17 61.8 5.4 2.1 1 1 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) Hydrolase_6 PF13344.1 EIE83998.1 - 1.3e-28 98.8 0.0 2.2e-28 98.1 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EIE83998.1 - 1.2e-13 50.5 0.0 3.3e-13 49.1 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.21 EIE83998.1 - 2.7e-05 24.7 0.0 0.00012 22.5 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EIE83998.1 - 8.3e-05 22.8 0.0 0.034 14.3 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase HSA PF07529.8 EIE83999.1 - 2.4e-17 62.4 5.5 2.4e-17 62.4 3.8 3.2 3 0 0 3 3 3 1 HSA Myb_DNA-bind_6 PF13921.1 EIE83999.1 - 7.2e-07 29.2 0.1 7.2e-07 29.2 0.0 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EIE83999.1 - 0.00036 20.5 0.8 0.00069 19.6 0.0 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain RRM_1 PF00076.17 EIE84000.1 - 2.2e-84 277.0 3.5 2.1e-20 72.1 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE84000.1 - 1.1e-54 182.3 0.7 3.5e-13 49.3 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE84000.1 - 1.3e-42 143.4 0.4 6.8e-10 38.6 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 EIE84000.1 - 1e-30 105.1 0.7 6.4e-30 102.6 0.6 2.3 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain Nup35_RRM_2 PF14605.1 EIE84000.1 - 4.3e-05 23.1 0.1 6.6 6.5 0.0 4.2 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 EIE84000.1 - 6.8e-05 22.6 8.2 0.066 13.0 2.2 3.9 3 1 1 4 4 4 2 RNA binding motif OB_RNB PF08206.6 EIE84000.1 - 9.9e-05 21.7 0.4 1.2 8.7 0.0 3.4 3 0 0 3 3 3 2 Ribonuclease B OB domain CbiG_mid PF11761.3 EIE84000.1 - 0.0015 18.7 0.0 0.93 9.7 0.0 3.2 3 0 0 3 3 3 1 Cobalamin biosynthesis central region DUF4523 PF15023.1 EIE84000.1 - 0.046 13.2 0.0 27 4.2 0.0 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF4523) DUF423 PF04241.10 EIE84001.1 - 3.7e-21 74.8 0.4 4.7e-21 74.5 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF423) LRR_4 PF12799.2 EIE84002.1 - 4.1e-38 128.3 47.3 8.2e-09 34.8 2.3 7.5 5 2 2 7 7 7 7 Leucine Rich repeats (2 copies) DEAD PF00270.24 EIE84002.1 - 1.6e-32 112.2 0.0 6.3e-32 110.3 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIE84002.1 - 2.7e-25 88.0 1.3 4.9e-25 87.2 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain LRR_8 PF13855.1 EIE84002.1 - 9.1e-20 70.1 43.4 4.5e-08 32.7 5.3 5.9 3 1 4 8 8 8 6 Leucine rich repeat LRR_9 PF14580.1 EIE84002.1 - 1.4e-11 44.2 23.6 5.6e-06 26.0 4.9 3.6 2 1 2 4 4 4 3 Leucine-rich repeat LRR_1 PF00560.28 EIE84002.1 - 2e-08 33.1 37.4 0.82 9.9 0.3 10.8 11 1 0 11 11 11 6 Leucine Rich Repeat LRR_6 PF13516.1 EIE84002.1 - 6.7e-05 22.5 31.4 0.41 10.8 0.3 9.9 7 2 4 11 11 11 2 Leucine Rich repeat LRR_7 PF13504.1 EIE84002.1 - 0.0034 17.3 23.7 12 6.6 0.2 9.2 8 1 1 9 9 9 2 Leucine rich repeat MRL1 PF13003.2 EIE84003.1 - 0.027 14.2 0.4 0.029 14.1 0.3 1.0 1 0 0 1 1 1 0 Ribosomal protein L1 DUF3694 PF12473.3 EIE84003.1 - 0.04 13.5 0.2 0.042 13.5 0.1 1.1 1 0 0 1 1 1 0 Kinesin protein WD40 PF00400.27 EIE84004.1 - 4.1e-12 45.4 3.9 1.1e-05 25.1 0.1 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat Myb_DNA-binding PF00249.26 EIE84004.1 - 0.0026 17.7 0.1 0.006 16.6 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain MAAL_C PF07476.6 EIE84004.1 - 0.022 13.7 0.1 0.035 13.0 0.0 1.3 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus Thioredoxin_8 PF13905.1 EIE84004.1 - 0.33 11.1 3.1 45 4.2 0.0 3.4 3 1 0 3 3 3 0 Thioredoxin-like TPR_11 PF13414.1 EIE84006.1 - 2.1e-21 75.3 1.4 2.2e-07 30.4 0.0 3.9 2 2 3 5 5 5 5 TPR repeat TPR_1 PF00515.23 EIE84006.1 - 4.8e-21 73.4 0.0 0.00016 21.1 0.0 4.7 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.12 EIE84006.1 - 6.1e-18 63.2 1.8 0.0036 17.1 0.0 5.4 5 1 1 6 6 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 EIE84006.1 - 9.2e-15 54.8 4.0 0.00041 20.9 0.1 4.9 3 2 2 5 5 4 4 Tetratricopeptide repeat TPR_14 PF13428.1 EIE84006.1 - 7.4e-14 51.0 5.3 0.00021 21.6 0.3 5.8 4 2 2 6 6 5 4 Tetratricopeptide repeat TPR_17 PF13431.1 EIE84006.1 - 2.8e-13 48.9 0.2 0.36 11.1 0.0 5.8 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.1 EIE84006.1 - 6.4e-12 45.2 0.7 0.011 15.6 0.0 4.5 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.1 EIE84006.1 - 2.4e-11 43.8 0.3 0.016 15.5 0.2 4.6 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.1 EIE84006.1 - 7e-09 34.8 0.0 0.29 11.0 0.0 4.5 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_20 PF14561.1 EIE84006.1 - 9.6e-09 35.2 0.0 0.00051 20.0 0.2 4.5 2 2 3 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 EIE84006.1 - 9.7e-07 28.1 1.7 0.36 10.7 0.0 4.9 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 EIE84006.1 - 2.4e-06 27.6 0.1 3.7 8.2 0.0 5.7 6 0 0 6 6 5 1 Tetratricopeptide repeat Apc3 PF12895.2 EIE84006.1 - 5.7e-06 26.3 0.5 0.0073 16.4 0.0 2.7 2 1 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EIE84006.1 - 5.5e-05 22.9 0.2 1.3 8.9 0.1 3.8 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.1 EIE84006.1 - 0.0033 16.5 0.0 0.036 13.1 0.0 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat DUF4248 PF14053.1 EIE84006.1 - 0.0065 16.0 0.3 0.029 13.9 0.1 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF4248) MIT PF04212.13 EIE84006.1 - 0.032 14.1 0.4 8 6.4 0.0 3.4 3 2 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.1 EIE84006.1 - 0.27 11.2 2.3 4.7 7.2 0.0 3.3 3 0 0 3 3 2 0 Tetratricopeptide repeat Velvet PF11754.3 EIE84007.1 - 0.0019 17.8 0.0 0.0019 17.8 0.0 1.1 1 0 0 1 1 1 1 Velvet factor Homeobox_KN PF05920.6 EIE84008.1 - 5.8e-18 64.3 0.5 5.8e-18 64.3 0.3 2.2 2 0 0 2 2 2 1 Homeobox KN domain Homeobox PF00046.24 EIE84008.1 - 3.9e-08 32.7 0.7 3.9e-08 32.7 0.5 1.9 2 0 0 2 2 2 1 Homeobox domain DUF3446 PF11928.3 EIE84008.1 - 0.033 14.3 4.9 0.057 13.6 3.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) DUF515 PF04415.7 EIE84008.1 - 1.8 6.7 5.9 2.4 6.3 4.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) ubiquitin PF00240.18 EIE84010.1 - 3.9e-136 442.6 25.2 9e-34 114.7 0.8 4.0 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.3 EIE84010.1 - 6.1e-77 253.3 21.6 9.3e-19 66.8 0.5 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EIE84010.1 - 3.8e-24 84.7 13.0 0.00012 22.2 0.1 5.8 4 4 0 4 4 4 4 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EIE84010.1 - 2e-20 73.0 0.9 0.0026 17.4 0.0 4.0 4 0 0 4 4 4 4 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EIE84010.1 - 5.7e-14 51.9 3.4 0.12 12.3 0.0 4.9 4 3 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EIE84010.1 - 1e-13 51.2 2.7 0.13 12.4 0.0 4.2 1 1 1 4 4 4 4 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 EIE84010.1 - 1.5e-10 41.0 0.0 1.5 8.8 0.0 4.6 4 0 0 4 4 4 4 Protein of unknown function (DUF2870) TUG-UBL1 PF11470.3 EIE84010.1 - 7.4e-07 28.9 6.0 3.6 7.5 0.0 4.2 4 0 0 4 4 4 4 GLUT4 regulating protein TUG Methyltrans_RNA PF04452.9 EIE84010.1 - 7.9e-06 25.1 1.0 2 7.5 0.0 3.3 3 0 0 3 3 3 3 RNA methyltransferase Big_3_3 PF13750.1 EIE84010.1 - 6.3e-05 22.4 0.1 24 4.3 0.0 4.1 4 0 0 4 4 4 0 Bacterial Ig-like domain (group 3) DUF3861 PF12977.2 EIE84010.1 - 7e-05 22.8 6.8 13 5.9 0.1 4.4 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) ACT_4 PF13291.1 EIE84010.1 - 0.00049 20.3 2.1 54 4.2 0.0 4.2 4 0 0 4 4 4 0 ACT domain FlgD_ig PF13860.1 EIE84010.1 - 0.00077 19.1 4.1 32 4.3 0.0 4.2 4 0 0 4 4 4 0 FlgD Ig-like domain USP7_C2 PF14533.1 EIE84010.1 - 0.0036 16.7 7.1 7 6.0 0.6 3.9 1 1 0 3 3 3 0 Ubiquitin-specific protease C-terminal Plexin_cytopl PF08337.7 EIE84010.1 - 0.0045 15.3 13.6 4 5.6 0.2 5.6 5 3 0 5 5 5 3 Plexin cytoplasmic RasGAP domain GABP-alpha PF11620.3 EIE84010.1 - 0.0066 16.4 9.4 21 5.1 0.1 4.1 4 0 0 4 4 4 0 GA-binding protein alpha chain DUF493 PF04359.9 EIE84010.1 - 0.0075 16.6 0.6 1.4e+02 2.9 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF493) DUF3781 PF12636.2 EIE84010.1 - 0.0086 16.0 8.7 30 4.6 0.1 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF3781) CTDII PF01556.13 EIE84010.1 - 0.011 15.5 14.1 6.1 6.8 0.2 4.2 1 1 2 4 4 4 0 DnaJ C terminal domain Coagulin PF02035.10 EIE84010.1 - 0.1 12.3 5.1 78 2.8 0.0 4.0 4 0 0 4 4 4 0 Coagulin Tash_PEST PF07708.6 EIE84010.1 - 0.14 12.1 31.7 4.5 7.3 1.6 4.3 4 0 0 4 4 4 0 Tash protein PEST motif P2 PF07194.6 EIE84010.1 - 3.7 7.4 14.6 50 3.8 0.2 4.3 4 0 0 4 4 4 0 P2 response regulator binding domain FERM_N PF09379.5 EIE84010.1 - 6.1 6.9 10.8 1.7e+02 2.3 0.1 5.6 4 4 0 4 4 4 0 FERM N-terminal domain Myosin_N PF02736.14 EIE84010.1 - 9.6 5.9 9.7 1.1e+02 2.5 0.1 4.3 4 0 0 4 4 4 0 Myosin N-terminal SH3-like domain Lipase_GDSL PF00657.17 EIE84012.1 - 0.0016 18.3 0.0 0.0016 18.3 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase TMEM219 PF14940.1 EIE84012.1 - 0.023 13.8 0.3 3.4 6.7 0.0 2.1 1 1 1 2 2 2 0 Transmembrane 219 Lipase_GDSL_2 PF13472.1 EIE84012.1 - 0.12 12.4 0.0 0.13 12.4 0.0 1.1 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family MMS1_N PF10433.4 EIE84015.1 - 1.2e-33 116.0 0.4 2.4e-33 115.0 0.3 1.4 1 1 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term TUDOR PF00567.19 EIE84015.1 - 0.081 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Tudor domain DDE_3 PF13358.1 EIE84017.1 - 2.9e-15 56.2 0.0 3e-15 56.2 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DNA_topoisoIV PF00521.15 EIE84019.1 - 1.1e-117 393.4 0.4 2.4e-117 392.3 0.3 1.6 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 EIE84019.1 - 6.8e-36 123.0 1.9 1.3e-35 122.1 0.5 2.2 2 0 0 2 2 2 1 DNA gyrase B Toprim PF01751.17 EIE84019.1 - 1.6e-12 47.2 0.6 6.9e-12 45.2 0.0 2.4 2 0 0 2 2 2 1 Toprim domain HATPase_c PF02518.21 EIE84019.1 - 1.6e-10 40.6 0.0 4.6e-10 39.2 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ndc1_Nup PF09531.5 EIE84019.1 - 1.2 7.4 6.8 2.5 6.4 4.7 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup LRR_8 PF13855.1 EIE84020.1 - 2.4e-10 40.0 27.9 7.4e-05 22.4 4.9 3.2 1 1 4 5 5 5 5 Leucine rich repeat LRR_1 PF00560.28 EIE84020.1 - 5.9e-09 34.7 13.2 0.18 11.9 0.1 6.7 7 0 0 7 7 7 3 Leucine Rich Repeat LRR_4 PF12799.2 EIE84020.1 - 0.00063 19.3 15.9 0.11 12.0 2.8 3.8 1 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EIE84020.1 - 0.0044 16.9 11.9 0.6 10.3 0.2 5.9 6 0 0 6 6 6 1 Leucine Rich repeat LRRNT_2 PF08263.7 EIE84020.1 - 0.0046 16.8 8.7 0.011 15.6 6.0 1.7 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain Dynamitin PF04912.9 EIE84020.1 - 0.064 12.0 0.0 0.14 10.9 0.0 1.5 1 1 1 2 2 2 0 Dynamitin RRM_1 PF00076.17 EIE84022.1 - 2.7e-10 39.7 0.0 4.3e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RanBP PF00641.13 EIE84022.1 - 2.7e-07 29.5 2.8 4.5e-07 28.8 1.9 1.3 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others RRM_6 PF14259.1 EIE84022.1 - 3.2e-06 27.0 0.0 5.5e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Cyclin PF08613.6 EIE84023.1 - 1.2e-17 64.6 0.5 2.3e-17 63.7 0.3 1.5 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EIE84023.1 - 0.00027 20.5 1.1 0.0084 15.6 0.8 2.4 1 1 0 1 1 1 1 Cyclin, N-terminal domain GCR1_C PF12550.3 EIE84024.1 - 5.3e-26 90.3 0.7 5.1e-25 87.1 0.2 2.6 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes Chitin_synth_2 PF03142.10 EIE84026.1 - 1.7e-95 320.4 0.3 2.2e-70 237.5 0.0 2.1 2 0 0 2 2 2 2 Chitin synthase Glyco_tranf_2_3 PF13641.1 EIE84026.1 - 9.6e-06 25.5 0.0 0.0006 19.6 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EIE84026.1 - 0.00024 20.8 0.0 0.24 11.0 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 Cyt-b5 PF00173.23 EIE84026.1 - 0.00035 20.2 0.0 0.03 14.1 0.0 2.8 2 1 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glyco_transf_21 PF13506.1 EIE84026.1 - 0.0015 17.8 0.0 0.0028 16.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 ProRS-C_1 PF09180.6 EIE84027.1 - 7.7e-22 76.9 0.1 2.6e-21 75.2 0.1 2.0 2 0 0 2 2 2 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.20 EIE84027.1 - 1.4e-21 76.8 0.0 2.8e-21 75.8 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EIE84027.1 - 3.6e-19 68.4 0.0 2.9e-18 65.5 0.0 2.5 2 0 0 2 2 2 1 Anticodon binding domain tRNA_edit PF04073.10 EIE84027.1 - 1.9e-17 63.2 0.3 3.4e-17 62.4 0.2 1.5 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain Ribosomal_60s PF00428.14 EIE84027.1 - 0.48 10.8 8.0 0.54 10.6 0.6 3.2 3 0 0 3 3 3 0 60s Acidic ribosomal protein DUF2482 PF10655.4 EIE84028.1 - 0.088 12.8 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Hypothetical protein of unknown function (DUF2482) Tubulin_3 PF14881.1 EIE84031.1 - 4.3e-39 133.8 0.3 1.2e-38 132.4 0.2 1.7 1 1 0 1 1 1 1 Tubulin domain Tubulin PF00091.20 EIE84031.1 - 0.00072 19.4 0.1 0.0017 18.2 0.0 1.6 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain NDT80_PhoG PF05224.7 EIE84032.1 - 2.3e-36 125.5 0.6 7.6e-18 65.1 0.0 3.1 2 1 1 3 3 3 2 NDT80 / PhoG like DNA-binding family Mito_fiss_reg PF05308.6 EIE84032.1 - 7.6 5.8 7.3 4.2 6.6 3.6 1.7 1 1 0 1 1 1 0 Mitochondrial fission regulator AlaDh_PNT_C PF01262.16 EIE84034.1 - 3.1e-22 78.9 0.4 7.1e-20 71.2 0.0 3.0 2 1 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Saccharop_dh PF03435.13 EIE84034.1 - 4.7e-13 48.8 0.1 7.2e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 EIE84034.1 - 1.8e-05 24.8 0.2 5.2e-05 23.3 0.1 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase adh_short PF00106.20 EIE84034.1 - 0.023 14.6 0.0 0.038 13.9 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Semialdhyde_dh PF01118.19 EIE84034.1 - 0.037 14.3 0.1 0.091 13.0 0.0 1.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain DUF3184 PF11380.3 EIE84034.1 - 0.051 11.5 0.0 0.065 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3184) NAD_binding_7 PF13241.1 EIE84034.1 - 0.12 12.6 0.1 0.34 11.2 0.0 1.7 2 0 0 2 2 2 0 Putative NAD(P)-binding MT-A70 PF05063.9 EIE84035.1 - 2.4e-19 69.5 0.2 5.2e-19 68.4 0.1 1.5 1 0 0 1 1 1 1 MT-A70 SET PF00856.23 EIE84036.1 - 7.3e-13 49.1 0.5 7.6e-12 45.8 0.0 2.4 3 0 0 3 3 3 1 SET domain SSXRD PF09514.5 EIE84036.1 - 0.0016 17.7 0.1 0.0039 16.4 0.1 1.7 1 0 0 1 1 1 1 SSXRD motif ATP-synt_S1 PF05827.7 EIE84037.1 - 2.1e-17 63.3 11.8 5.5e-13 48.8 2.6 2.0 1 1 1 2 2 2 2 Vacuolar ATP synthase subunit S1 (ATP6S1) Flavodoxin_5 PF12724.2 EIE84037.1 - 0.0022 18.0 0.1 0.0041 17.1 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin domain SOUL PF04832.7 EIE84037.1 - 0.03 13.8 0.1 0.051 13.1 0.1 1.4 1 0 0 1 1 1 0 SOUL heme-binding protein Agro_virD5 PF04730.7 EIE84037.1 - 0.085 10.9 0.3 0.088 10.8 0.2 1.1 1 0 0 1 1 1 0 Agrobacterium VirD5 protein SPRY PF00622.23 EIE84038.1 - 2.7e-18 66.2 0.3 2.7e-18 66.2 0.2 1.5 2 0 0 2 2 2 1 SPRY domain Ferritin PF00210.19 EIE84039.1 - 9.9e-45 151.7 1.3 1.2e-44 151.5 0.9 1.0 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.12 EIE84039.1 - 1.8e-06 28.2 0.2 2.5e-06 27.8 0.1 1.3 1 0 0 1 1 1 1 Rubrerythrin DUF4185 PF13810.1 EIE84039.1 - 0.033 13.0 0.1 0.044 12.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4185) Ribul_P_3_epim PF00834.14 EIE84040.1 - 3.8e-74 248.1 0.0 4.8e-74 247.8 0.0 1.1 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.14 EIE84040.1 - 0.0024 17.4 0.1 0.0059 16.1 0.0 1.9 2 1 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain PcrB PF01884.12 EIE84040.1 - 0.012 14.8 0.1 0.021 14.1 0.1 1.6 1 1 0 1 1 1 0 PcrB family OMPdecase PF00215.19 EIE84040.1 - 0.026 13.9 0.0 0.035 13.5 0.0 1.3 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family JmjN PF02375.12 EIE84040.1 - 0.13 11.8 0.0 0.82 9.2 0.0 2.3 3 0 0 3 3 3 0 jmjN domain S6PP PF05116.8 EIE84041.1 - 0.0087 15.3 0.2 0.012 14.8 0.2 1.2 1 0 0 1 1 1 1 Sucrose-6F-phosphate phosphohydrolase Ndc1_Nup PF09531.5 EIE84041.1 - 2.8 6.2 7.1 3.1 6.0 4.9 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SNARE PF05739.14 EIE84042.1 - 3.5e-19 68.2 5.7 3.5e-19 68.2 3.9 2.5 2 1 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 EIE84042.1 - 4.1e-13 49.3 6.1 4.1e-13 49.3 4.2 2.7 2 0 0 2 2 2 1 Syntaxin Syntaxin_2 PF14523.1 EIE84042.1 - 0.0011 18.9 7.4 0.0011 18.9 5.1 2.9 2 2 0 2 2 2 1 Syntaxin-like protein Vac_Fusion PF02346.11 EIE84042.1 - 0.014 14.7 0.4 0.014 14.7 0.3 3.2 4 0 0 4 4 4 0 Chordopoxvirus fusion protein DUF4094 PF13334.1 EIE84042.1 - 0.02 15.2 0.4 0.02 15.2 0.3 3.4 3 2 0 3 3 3 0 Domain of unknown function (DUF4094) DUF2873 PF11395.3 EIE84042.1 - 0.037 13.5 3.2 0.073 12.6 2.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2873) Laminin_II PF06009.7 EIE84042.1 - 0.61 9.8 15.9 2.5 7.8 3.4 2.5 2 0 0 2 2 2 0 Laminin Domain II DUF1759 PF03564.10 EIE84042.1 - 0.85 9.4 10.7 1.4 8.6 0.7 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1759) Syntaxin-6_N PF09177.6 EIE84042.1 - 1.8 9.0 12.6 8.1 6.9 1.0 3.3 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Med28 PF11594.3 EIE84042.1 - 3.1 8.0 14.2 0.74 10.0 0.6 3.4 2 1 1 3 3 3 0 Mediator complex subunit 28 Ribosomal_S13 PF00416.17 EIE84042.1 - 7.5 7.0 11.0 11 6.5 0.6 3.3 3 0 0 3 3 3 0 Ribosomal protein S13/S18 SUI1 PF01253.17 EIE84043.1 - 2e-12 46.7 0.1 3.7e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 SF-assemblin PF06705.6 EIE84043.1 - 0.0031 16.7 0.2 0.0031 16.7 0.2 1.3 2 0 0 2 2 2 1 SF-assemblin/beta giardin SH2_2 PF14633.1 EIE84043.1 - 0.038 13.0 0.1 0.045 12.8 0.1 1.2 1 0 0 1 1 1 0 SH2 domain BTB PF00651.26 EIE84043.1 - 0.084 12.8 0.1 0.2 11.6 0.0 1.7 2 0 0 2 2 2 0 BTB/POZ domain Lipase_GDSL_2 PF13472.1 EIE84044.1 - 7.6e-23 81.5 0.0 9.1e-23 81.2 0.0 1.0 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EIE84044.1 - 1.3e-20 74.2 0.0 1.6e-20 73.9 0.0 1.0 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Transferase PF02458.10 EIE84045.1 - 3.7e-63 213.4 0.1 4.7e-63 213.1 0.0 1.0 1 0 0 1 1 1 1 Transferase family DUF4243 PF14027.1 EIE84046.1 - 1.6e-66 225.0 0.1 2.8e-66 224.2 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF4243) Cyt-b5 PF00173.23 EIE84047.1 - 1.6e-20 72.7 0.1 3.3e-20 71.6 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 EIE84047.1 - 1.4e-08 35.1 23.0 1.4e-08 35.1 15.9 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Abi PF02517.11 EIE84047.1 - 1.2 9.3 14.4 0.07 13.2 3.7 2.3 1 1 1 2 2 2 0 CAAX protease self-immunity DNA_pol_E_B PF04042.11 EIE84048.1 - 7.4e-50 169.0 0.1 1.4e-49 168.1 0.1 1.5 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Apt1 PF10351.4 EIE84049.1 - 3.2e-69 233.9 9.2 3.2e-69 233.9 6.4 2.3 1 1 1 2 2 2 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.4 EIE84049.1 - 6.3e-47 160.0 16.9 1.3e-31 109.5 9.3 2.5 1 1 1 2 2 2 2 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.4 EIE84049.1 - 2.9e-32 111.7 0.0 3.9e-31 108.0 0.0 2.9 4 0 0 4 4 4 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 EIE84049.1 - 2.4e-21 76.1 1.0 5.7e-21 74.8 0.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.4 EIE84049.1 - 5.5e-08 33.1 0.2 3.7e-06 27.3 0.0 3.6 2 1 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Homeobox PF00046.24 EIE84050.1 - 3.6e-20 71.3 1.1 7e-20 70.3 0.7 1.5 1 0 0 1 1 1 1 Homeobox domain Helicase_C PF00271.26 EIE84051.1 - 3.8e-13 49.1 0.1 8.3e-13 48.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EIE84051.1 - 2.3e-07 30.4 0.0 7.6e-07 28.7 0.0 2.0 1 1 1 2 2 2 1 DEAD/DEAH box helicase HAP1_N PF04849.8 EIE84052.1 - 0.0025 16.8 39.2 0.004 16.1 27.2 1.2 1 0 0 1 1 1 1 HAP1 N-terminal conserved region NPV_P10 PF05531.7 EIE84052.1 - 0.17 12.1 6.3 0.35 11.1 0.1 3.3 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Cbl_N PF02262.11 EIE84052.1 - 0.64 9.7 9.6 0.062 13.0 2.9 2.0 2 1 0 2 2 2 0 CBL proto-oncogene N-terminal domain 1 DUF4446 PF14584.1 EIE84052.1 - 5.4 6.8 19.9 0.18 11.6 2.4 3.3 1 1 1 3 3 3 0 Protein of unknown function (DUF4446) Tcp11 PF05794.8 EIE84053.1 - 1.3e-56 192.1 7.6 1.3e-56 192.1 5.3 1.7 2 0 0 2 2 2 1 T-complex protein 11 DUF4137 PF13593.1 EIE84054.1 - 2.1e-82 276.7 15.7 2.4e-82 276.5 10.9 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.11 EIE84054.1 - 3.1e-06 26.7 9.2 8.3e-06 25.3 6.4 1.7 1 0 0 1 1 1 1 Sodium Bile acid symporter family tRNA-synt_2d PF01409.15 EIE84055.1 - 1.8e-52 177.9 0.5 1.4e-30 106.3 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 EIE84055.1 - 1.9e-05 24.7 0.0 4.6e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain tRNA-synt_2 PF00152.15 EIE84055.1 - 0.039 12.7 0.4 1.6 7.3 0.0 2.3 2 1 0 2 2 2 0 tRNA synthetases class II (D, K and N) Transket_pyr PF02779.19 EIE84056.1 - 3.3e-63 212.3 0.0 5e-63 211.8 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 EIE84056.1 - 1.3e-60 204.7 0.0 1.7e-60 204.2 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component EF-hand_8 PF13833.1 EIE84057.1 - 2.6e-16 58.9 4.5 3.1e-09 36.2 0.3 3.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.1 EIE84057.1 - 1e-15 57.6 3.0 1.7e-15 56.8 1.2 1.7 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EIE84057.1 - 7.2e-14 49.9 1.5 9.1e-06 24.6 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 EIE84057.1 - 1e-08 34.3 6.3 1.9e-05 24.1 0.4 3.3 2 2 2 4 4 4 2 EF-hand domain EF-hand_4 PF12763.2 EIE84057.1 - 7.2e-05 22.4 1.7 0.072 12.8 0.2 2.9 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_5 PF13202.1 EIE84057.1 - 0.00028 20.1 0.3 0.00028 20.1 0.2 3.1 2 1 1 3 3 3 1 EF hand Trigger_C PF05698.9 EIE84057.1 - 0.00037 20.3 1.5 0.0011 18.7 0.2 2.0 2 0 0 2 2 2 1 Bacterial trigger factor protein (TF) C-terminus SPARC_Ca_bdg PF10591.4 EIE84057.1 - 0.0041 17.1 0.1 0.0054 16.7 0.1 1.3 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 EIE84057.1 - 0.0045 16.8 0.0 0.0078 16.1 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain DUF1456 PF07308.8 EIE84057.1 - 0.011 15.7 0.2 4 7.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1456) DUF2322 PF10084.4 EIE84057.1 - 0.015 15.0 0.1 0.021 14.5 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2322) Peptidase_C23 PF05379.6 EIE84057.1 - 0.015 15.2 0.2 0.049 13.6 0.0 1.9 1 1 0 2 2 2 0 Carlavirus endopeptidase PAH PF02671.16 EIE84057.1 - 0.038 13.6 0.1 11 5.6 0.0 2.5 2 0 0 2 2 2 0 Paired amphipathic helix repeat DUF1296 PF06972.6 EIE84057.1 - 0.22 11.5 1.8 4.3 7.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1296) PAH PF02671.16 EIE84058.1 - 8.7e-25 86.0 0.0 3.6e-15 55.3 0.0 2.4 2 0 0 2 2 2 2 Paired amphipathic helix repeat Sof1 PF04158.9 EIE84058.1 - 0.012 15.5 0.5 3.5 7.7 0.0 2.3 2 0 0 2 2 2 0 Sof1-like domain COX5A PF02284.11 EIE84058.1 - 0.013 15.4 0.2 4.8 7.1 0.0 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase subunit Va RR_TM4-6 PF06459.7 EIE84059.1 - 4.6e-05 23.4 10.7 9.3e-05 22.4 7.4 1.4 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 Merozoite_SPAM PF07133.6 EIE84059.1 - 0.00023 21.1 16.2 0.00069 19.5 11.2 2.0 1 0 0 1 1 1 1 Merozoite surface protein (SPAM) Nop14 PF04147.7 EIE84059.1 - 0.0024 15.9 17.3 0.0038 15.2 12.0 1.4 1 0 0 1 1 1 1 Nop14-like family TRAP_alpha PF03896.11 EIE84059.1 - 0.0072 15.3 11.0 0.013 14.4 7.6 1.4 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit Drc1-Sld2 PF11719.3 EIE84059.1 - 0.012 14.7 12.7 0.019 14.0 8.8 1.3 1 0 0 1 1 1 0 DNA replication and checkpoint protein Raftlin PF15250.1 EIE84059.1 - 0.03 12.8 6.8 0.042 12.3 4.7 1.2 1 0 0 1 1 1 0 Raftlin Daxx PF03344.10 EIE84059.1 - 0.072 11.5 20.3 0.1 11.0 14.1 1.2 1 0 0 1 1 1 0 Daxx Family DUF1510 PF07423.6 EIE84059.1 - 0.35 10.2 19.6 0.63 9.3 13.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Zip PF02535.17 EIE84059.1 - 0.5 9.3 4.0 0.64 8.9 2.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF3513 PF12026.3 EIE84059.1 - 0.56 9.7 7.7 1.2 8.6 5.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3513) Spore_coat_CotO PF14153.1 EIE84059.1 - 0.63 9.4 17.8 0.059 12.8 8.9 1.8 2 0 0 2 2 2 0 Spore coat protein CotO Serinc PF03348.10 EIE84059.1 - 0.7 8.5 5.5 0.21 10.2 1.8 1.5 2 0 0 2 2 2 0 Serine incorporator (Serinc) CDC45 PF02724.9 EIE84059.1 - 1.9 6.4 19.1 0.018 13.0 8.0 1.6 2 0 0 2 2 2 0 CDC45-like protein PBP_sp32 PF07222.7 EIE84059.1 - 2.3 7.3 17.4 3.9 6.5 12.0 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 AIF_C PF14721.1 EIE84059.1 - 6 7.1 7.9 3.5 7.8 3.6 2.0 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term YqfQ PF14181.1 EIE84059.1 - 6.4 6.7 17.5 18 5.3 12.1 1.7 1 0 0 1 1 1 0 YqfQ-like protein zf-DHHC PF01529.15 EIE84060.1 - 2.5e-11 43.2 8.2 2.5e-11 43.2 5.7 2.2 1 1 1 2 2 2 1 DHHC palmitoyltransferase FYVE PF01363.16 EIE84060.1 - 0.017 14.9 3.7 0.017 14.9 2.6 1.7 2 0 0 2 2 2 0 FYVE zinc finger SET PF00856.23 EIE84061.1 - 1.5e-20 74.1 4.7 4.3e-17 62.8 0.1 3.8 3 1 1 4 4 4 2 SET domain WW PF00397.21 EIE84061.1 - 3.1e-07 30.1 3.0 7e-07 28.9 2.1 1.6 1 0 0 1 1 1 1 WW domain SRI PF08236.6 EIE84061.1 - 1.3e-05 25.0 2.6 1.3e-05 25.0 1.8 2.5 2 0 0 2 2 2 1 SRI (Set2 Rpb1 interacting) domain Med26 PF08711.6 EIE84061.1 - 0.0014 18.0 0.1 0.089 12.3 0.0 2.9 2 0 0 2 2 2 1 TFIIS helical bundle-like domain DUF4629 PF15442.1 EIE84061.1 - 0.018 15.1 2.1 0.018 15.1 1.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4629) CENP-B_dimeris PF09026.5 EIE84061.1 - 0.11 12.7 8.4 0.33 11.2 5.8 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF445 PF04286.7 EIE84061.1 - 3.7 6.9 12.5 1.7 8.1 3.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF445) FYRC PF05965.9 EIE84062.1 - 5.4e-09 35.7 0.1 1e-08 34.8 0.0 1.4 1 1 0 1 1 1 1 F/Y rich C-terminus Gtr1_RagA PF04670.7 EIE84063.1 - 8.6e-69 231.2 0.6 1.3e-68 230.6 0.4 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 EIE84063.1 - 6.8e-09 35.1 0.1 1.4e-08 34.2 0.1 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family DUF4350 PF14258.1 EIE84063.1 - 0.1 12.8 0.0 22 5.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4350) Fe-S_biosyn PF01521.15 EIE84064.1 - 8.3e-19 67.5 0.0 1.1e-18 67.1 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Ribosomal_L6e PF01159.14 EIE84065.1 - 1.5e-35 121.6 0.7 1.5e-35 121.6 0.5 1.7 2 0 0 2 2 2 1 Ribosomal protein L6e Ribosomal_L6e_N PF03868.10 EIE84065.1 - 7.1e-14 51.4 1.0 7.1e-14 51.4 0.7 2.2 2 1 0 2 2 2 1 Ribosomal protein L6, N-terminal domain zf-RING_4 PF14570.1 EIE84067.1 - 2.2e-21 75.1 10.9 5.2e-21 73.9 7.6 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.1 EIE84067.1 - 0.027 14.4 11.7 0.056 13.4 8.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.1 EIE84067.1 - 0.11 12.2 4.1 0.33 10.7 2.9 1.7 1 0 0 1 1 1 0 Zinc-binding RING-finger Baculo_IE-1 PF05290.6 EIE84067.1 - 0.14 11.8 3.7 0.33 10.6 2.5 1.6 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) TPR_11 PF13414.1 EIE84068.1 - 3.9e-14 52.0 7.7 1.6e-06 27.6 1.2 3.0 2 1 1 3 3 3 2 TPR repeat TPR_1 PF00515.23 EIE84068.1 - 2.4e-08 33.2 6.3 0.00064 19.2 0.0 4.2 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EIE84068.1 - 1.3e-06 27.8 6.8 0.0018 18.0 0.0 4.1 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 EIE84068.1 - 1.9e-06 28.4 0.4 0.03 14.9 0.1 2.9 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EIE84068.1 - 7.1e-06 26.2 0.1 0.034 14.7 0.1 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 EIE84068.1 - 9.3e-06 25.0 1.9 0.0043 16.7 0.1 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EIE84068.1 - 0.005 17.1 2.7 0.33 11.3 2.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EIE84068.1 - 0.016 15.0 0.1 0.016 15.0 0.1 2.9 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.1 EIE84068.1 - 0.017 15.0 2.8 0.63 10.0 0.0 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 EIE84068.1 - 0.021 15.0 1.7 0.2 11.9 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 EIE84068.1 - 0.062 13.1 4.2 1.1 9.1 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.13 EIE84068.1 - 1.5 8.7 8.1 6.1 6.8 0.3 3.0 1 1 1 2 2 2 0 MIT (microtubule interacting and transport) domain zf-C2H2 PF00096.21 EIE84069.1 - 5.1e-09 35.9 15.0 5.8e-05 23.1 1.1 2.9 3 0 0 3 3 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIE84069.1 - 8.7e-09 35.1 13.5 0.00011 22.2 1.4 2.9 2 1 1 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EIE84069.1 - 1.2e-07 31.7 3.1 1.2e-07 31.7 2.1 3.2 3 0 0 3 3 3 1 Zinc-finger double domain FimP PF09766.4 EIE84069.1 - 0.0061 15.6 15.4 0.0061 15.6 10.7 1.7 2 0 0 2 2 2 1 Fms-interacting protein Ebola_NP PF05505.7 EIE84069.1 - 0.018 13.1 7.3 0.018 13.1 5.0 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein FYDLN_acid PF09538.5 EIE84069.1 - 0.019 15.5 1.4 0.37 11.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) DUF4175 PF13779.1 EIE84069.1 - 0.023 12.3 24.7 0.031 12.0 17.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) AFT PF08731.6 EIE84069.1 - 0.025 14.7 7.7 0.18 12.0 3.1 2.2 2 0 0 2 2 2 0 Transcription factor AFT TFIIA PF03153.8 EIE84069.1 - 0.075 12.9 18.6 0.095 12.5 12.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Serinc PF03348.10 EIE84069.1 - 0.14 10.8 4.6 0.17 10.5 3.2 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) CagX PF03524.10 EIE84069.1 - 0.15 11.3 9.2 0.023 13.9 4.0 1.5 2 0 0 2 2 1 0 Conjugal transfer protein RRP14 PF15459.1 EIE84069.1 - 0.23 11.5 24.0 0.051 13.6 9.9 2.7 3 0 0 3 3 2 0 60S ribosome biogenesis protein Rrp14 OATP PF03137.15 EIE84069.1 - 0.28 9.1 7.4 0.022 12.8 2.0 1.4 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family SprA-related PF12118.3 EIE84069.1 - 0.34 10.1 21.4 0.058 12.7 12.3 1.6 2 0 0 2 2 2 0 SprA-related family FlaG PF03646.10 EIE84069.1 - 0.35 11.0 16.2 0.13 12.4 9.1 1.8 2 0 0 2 2 2 0 FlaG protein FHIPEP PF00771.15 EIE84069.1 - 0.39 8.9 2.5 0.47 8.7 1.8 1.1 1 0 0 1 1 1 0 FHIPEP family Folate_carrier PF01770.13 EIE84069.1 - 0.52 8.7 3.5 0.75 8.2 2.4 1.3 1 0 0 1 1 1 0 Reduced folate carrier Neur_chan_memb PF02932.11 EIE84069.1 - 0.57 10.0 8.5 0.63 9.8 5.9 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PAT1 PF09770.4 EIE84069.1 - 1.1 7.4 37.6 1.5 6.9 26.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4407 PF14362.1 EIE84069.1 - 1.5 7.7 8.9 0.17 10.7 3.7 1.3 2 0 0 2 2 1 0 Domain of unknown function (DUF4407) CRF1 PF10380.4 EIE84069.1 - 2.4 8.5 6.2 1.1 9.6 2.0 2.0 2 0 0 2 2 2 0 Transcription factor CRF1 AIF_C PF14721.1 EIE84069.1 - 3 8.0 8.2 1.2 9.4 3.6 1.8 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term BRF1 PF07741.8 EIE84069.1 - 3.1 8.0 14.3 2.9 8.1 6.3 2.3 2 0 0 2 2 2 0 Brf1-like TBP-binding domain EIIBC-GUT_N PF03612.9 EIE84069.1 - 3.2 7.3 7.9 0.57 9.7 3.0 1.6 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Activator_LAG-3 PF11498.3 EIE84069.1 - 3.2 6.3 38.8 4.3 5.9 26.9 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF605 PF04652.11 EIE84069.1 - 4.2 6.6 19.0 6.6 6.0 13.2 1.3 1 0 0 1 1 1 0 Vta1 like Conotoxin PF02950.12 EIE84069.1 - 7.8 7.3 11.6 2.9 8.7 5.1 2.2 2 0 0 2 2 2 0 Conotoxin DDRGK PF09756.4 EIE84069.1 - 9.8 5.5 18.3 3 7.2 9.8 1.9 2 0 0 2 2 2 0 DDRGK domain RhoGEF PF00621.15 EIE84070.1 - 4.9e-34 117.7 0.8 4.9e-34 117.7 0.6 2.0 2 0 0 2 2 2 1 RhoGEF domain DEP PF00610.16 EIE84070.1 - 8.1e-13 47.9 0.0 1.9e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_5 PF15405.1 EIE84070.1 - 9.1e-07 28.8 2.7 9.1e-07 28.8 1.8 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain IGPS PF00218.16 EIE84071.1 - 3.5e-97 324.4 1.5 5.5e-97 323.7 0.0 2.0 3 0 0 3 3 3 1 Indole-3-glycerol phosphate synthase PRAI PF00697.17 EIE84071.1 - 2.1e-61 206.9 0.1 1.1e-54 185.0 0.0 2.4 1 1 1 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.23 EIE84071.1 - 6e-54 182.4 0.1 1.2e-53 181.4 0.1 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EIE84071.1 - 8.5e-12 44.9 0.0 2.2e-11 43.6 0.0 1.7 1 0 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.14 EIE84071.1 - 0.022 14.2 2.1 0.19 11.2 0.0 3.3 4 0 0 4 4 4 0 Quinolinate phosphoribosyl transferase, C-terminal domain Homeobox PF00046.24 EIE84072.1 - 1.9e-16 59.3 5.0 1.9e-16 59.3 3.5 2.2 2 0 0 2 2 2 1 Homeobox domain Homeobox_KN PF05920.6 EIE84072.1 - 0.00017 21.2 1.1 0.00043 19.9 0.7 1.7 1 0 0 1 1 1 1 Homeobox KN domain SBP_bac_10 PF07596.6 EIE84072.1 - 0.016 15.2 1.2 0.12 12.3 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1559) Reticulon PF02453.12 EIE84073.1 - 1.4e-19 70.3 4.1 2e-19 69.8 2.9 1.2 1 0 0 1 1 1 1 Reticulon DUF3953 PF13129.1 EIE84073.1 - 0.14 11.7 2.2 11 5.7 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3953) PRT_C PF08372.5 EIE84073.1 - 0.29 10.6 1.8 1.4 8.4 0.0 2.3 1 1 1 2 2 2 0 Plant phosphoribosyltransferase C-terminal Peptidase_M22 PF00814.20 EIE84074.1 - 1.3e-63 215.0 0.0 2.7e-63 213.9 0.0 1.5 1 0 0 1 1 1 1 Glycoprotease family LicD PF04991.8 EIE84074.1 - 0.041 13.9 1.6 0.082 13.0 1.1 1.5 1 0 0 1 1 1 0 LicD family CmcH_NodU PF02543.10 EIE84074.1 - 0.25 10.4 0.0 0.25 10.4 0.0 2.0 1 1 0 2 2 2 0 Carbamoyltransferase DDRGK PF09756.4 EIE84074.1 - 3.5 6.9 15.9 6.1 6.2 11.0 1.3 1 0 0 1 1 1 0 DDRGK domain Cpn10 PF00166.16 EIE84075.1 - 4.7e-29 100.1 0.3 5.3e-29 100.0 0.2 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Rap_GAP PF02145.10 EIE84076.1 - 5.5e-13 48.7 0.0 1.3e-12 47.5 0.0 1.6 1 0 0 1 1 1 1 Rap/ran-GAP Rap_GAP PF02145.10 EIE84078.1 - 9.9e-46 155.4 0.1 1.5e-45 154.8 0.1 1.2 1 0 0 1 1 1 1 Rap/ran-GAP Whi5 PF08528.6 EIE84079.1 - 3.8e-06 26.3 0.6 8.7e-06 25.2 0.0 2.0 2 0 0 2 2 2 1 Whi5 like NAD_binding_5 PF07994.7 EIE84079.1 - 0.26 10.7 1.6 0.33 10.4 0.7 1.5 1 1 0 1 1 1 0 Myo-inositol-1-phosphate synthase Pmp3 PF01679.12 EIE84080.1 - 1.2e-18 66.5 6.1 1.5e-18 66.2 4.2 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator PrgI PF12666.2 EIE84080.1 - 0.01 15.9 0.4 0.013 15.6 0.3 1.1 1 0 0 1 1 1 0 PrgI family protein DUF445 PF04286.7 EIE84081.1 - 0.012 15.1 2.7 0.015 14.8 1.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Pex19 PF04614.7 EIE84081.1 - 0.027 14.0 10.2 0.034 13.7 4.7 2.1 2 0 0 2 2 2 0 Pex19 protein family NPV_P10 PF05531.7 EIE84081.1 - 4.2 7.6 7.4 0.96 9.7 0.3 2.4 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Kelch_4 PF13418.1 EIE84082.1 - 8.8e-25 86.2 3.2 8.7e-07 28.6 0.0 5.7 5 2 0 5 5 5 4 Galactose oxidase, central domain Kelch_3 PF13415.1 EIE84082.1 - 2.6e-21 75.2 5.3 0.0046 17.0 0.5 5.6 5 1 0 5 5 5 5 Galactose oxidase, central domain Kelch_6 PF13964.1 EIE84082.1 - 2e-16 59.3 11.8 0.00013 22.0 0.1 5.5 5 1 0 5 5 5 5 Kelch motif Kelch_1 PF01344.20 EIE84082.1 - 3.4e-11 42.5 19.7 3.6e-06 26.4 0.1 6.1 7 0 0 7 7 7 3 Kelch motif Kelch_5 PF13854.1 EIE84082.1 - 9.7e-11 41.3 4.8 0.00023 21.0 0.0 4.7 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.10 EIE84082.1 - 2.6e-08 33.3 7.2 0.00053 19.6 0.1 5.0 5 0 0 5 5 5 3 Kelch motif Muskelin_N PF06588.6 EIE84083.1 - 5e-35 120.9 0.1 5.3e-35 120.9 0.1 1.0 1 0 0 1 1 1 1 Muskelin N-terminus Sad1_UNC PF07738.8 EIE84083.1 - 0.083 12.6 0.0 0.1 12.4 0.0 1.1 1 0 0 1 1 1 0 Sad1 / UNC-like C-terminal Zn_clus PF00172.13 EIE84084.1 - 1.6e-10 40.6 12.2 2.6e-10 40.0 8.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Rep_fac-A_C PF08646.5 EIE84084.1 - 0.0046 16.6 3.0 0.0072 16.0 2.1 1.4 1 0 0 1 1 1 1 Replication factor-A C terminal domain PIF PF05092.7 EIE84084.1 - 0.0078 14.6 4.5 0.0078 14.6 3.1 1.3 2 0 0 2 2 2 1 Per os infectivity XhlA PF10779.4 EIE84084.1 - 0.08 12.8 0.1 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Haemolysin XhlA Blo-t-5 PF11642.3 EIE84084.1 - 0.085 12.6 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Mite allergen Blo t 5 Retrotrans_gag PF03732.12 EIE84085.1 - 0.029 14.4 0.9 0.042 13.9 0.6 1.2 1 0 0 1 1 1 0 Retrotransposon gag protein BioY PF02632.9 EIE84089.1 - 0.14 11.8 1.8 0.22 11.1 1.3 1.3 1 0 0 1 1 1 0 BioY family Ribosomal_L44 PF00935.14 EIE84091.1 - 9.7e-36 121.6 10.0 1.3e-35 121.1 6.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L44 Ribosomal_L33 PF00471.15 EIE84091.1 - 4.3 7.6 8.9 3.4 7.9 1.2 2.7 2 1 0 2 2 2 0 Ribosomal protein L33 HATPase_c_3 PF13589.1 EIE84092.1 - 1.4e-06 27.9 0.0 1.6e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EIE84092.1 - 0.00029 20.5 0.0 0.00033 20.3 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3469 PF11952.3 EIE84093.1 - 0.01 15.4 0.0 0.022 14.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3469) DUF244 PF03112.9 EIE84093.1 - 0.56 9.7 3.4 0.36 10.3 1.0 1.6 2 0 0 2 2 2 0 Uncharacterized protein family (ORF7) DUF Ribosomal_S3Ae PF01015.13 EIE84094.1 - 4.3e-66 221.9 5.6 5e-66 221.7 3.9 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Spt4 PF06093.8 EIE84094.1 - 0.081 12.8 0.3 0.73 9.7 0.0 2.3 2 0 0 2 2 2 0 Spt4/RpoE2 zinc finger DUF3571 PF12095.3 EIE84094.1 - 0.13 12.5 0.0 0.44 10.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3571) DUF496 PF04363.7 EIE84094.1 - 0.94 9.3 3.7 3.1 7.6 0.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF496) Ribosomal_S30 PF04758.9 EIE84095.1 - 3.9e-29 100.1 11.5 4.3e-29 100.0 8.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Pkinase PF00069.20 EIE84096.1 - 6.8e-19 68.0 0.0 4.5e-11 42.3 0.0 2.6 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIE84096.1 - 1.1e-06 27.9 0.0 0.02 13.9 0.0 2.4 1 1 1 2 2 2 2 Protein tyrosine kinase Lactamase_B_4 PF13691.1 EIE84096.1 - 0.026 13.9 0.0 0.062 12.7 0.0 1.5 1 0 0 1 1 1 0 tRNase Z endonuclease Fasciclin PF02469.17 EIE84097.1 - 1e-50 171.0 0.1 2.4e-14 53.4 0.0 4.2 4 0 0 4 4 4 4 Fasciclin domain Myb_DNA-binding PF00249.26 EIE84098.1 - 0.00019 21.3 0.1 0.00063 19.7 0.1 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EIE84098.1 - 0.025 14.7 0.0 0.089 12.9 0.0 2.0 1 0 0 1 1 1 0 Myb-like DNA-binding domain GTP_EFTU PF00009.22 EIE84099.1 - 1.8e-61 206.8 0.1 2.6e-61 206.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EIE84099.1 - 5.8e-36 122.6 0.0 1.5e-35 121.3 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 EIE84099.1 - 6.5e-23 80.4 0.0 1.6e-22 79.1 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EIE84099.1 - 5.5e-14 52.0 0.9 1.8e-13 50.3 0.1 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EIE84099.1 - 2.5e-13 49.6 0.0 5.6e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 EIE84099.1 - 0.00014 21.8 0.0 0.00032 20.6 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF3661 PF12400.3 EIE84100.1 - 1.5e-05 25.0 0.6 2.1e-05 24.6 0.4 1.2 1 0 0 1 1 1 1 Vaculolar membrane protein RVT_1 PF00078.22 EIE84101.1 - 1.4e-35 122.6 0.1 3.9e-35 121.1 0.1 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.1 EIE84101.1 - 1.5e-05 25.2 0.9 5.4e-05 23.4 0.6 2.0 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Rtt102p PF09510.5 EIE84102.1 - 0.13 12.2 0.2 0.13 12.2 0.1 2.5 3 0 0 3 3 3 0 Rtt102p-like transcription regulator protein RRM_1 PF00076.17 EIE84102.1 - 0.13 11.9 2.0 0.78 9.4 0.0 3.1 4 0 0 4 4 4 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.18 EIE84102.1 - 0.44 10.5 2.7 1.3 9.1 0.2 2.2 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.1 EIE84102.1 - 1.9 8.2 8.7 0.54 9.9 0.5 2.8 3 0 0 3 3 3 0 Zinc knuckle Kua-UEV1_localn PF10520.4 EIE84103.1 - 0.015 14.9 1.0 0.017 14.7 0.7 1.1 1 0 0 1 1 1 0 Kua-ubiquitin conjugating enzyme hybrid localisation domain Yos1 PF08571.5 EIE84103.1 - 0.026 14.6 0.0 0.04 14.0 0.0 1.3 1 1 0 1 1 1 0 Yos1-like PIF1 PF05970.9 EIE84104.1 - 1e-23 83.8 0.2 1.4e-13 50.5 0.0 3.8 1 1 1 2 2 2 2 PIF1-like helicase Herpes_Helicase PF02689.9 EIE84104.1 - 4.1e-05 21.5 0.0 0.0013 16.6 0.0 2.2 2 0 0 2 2 2 2 Helicase AAA_30 PF13604.1 EIE84104.1 - 0.00013 21.6 0.0 0.093 12.2 0.0 2.4 2 1 0 2 2 2 2 AAA domain UvrD_C_2 PF13538.1 EIE84104.1 - 0.004 17.2 0.0 0.01 15.9 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Helitron_like_N PF14214.1 EIE84105.1 - 4.9e-19 68.7 0.4 1.1e-18 67.6 0.3 1.6 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Phe_ZIP PF08916.6 EIE84105.1 - 0.019 15.2 0.5 0.1 12.9 0.0 2.5 3 0 0 3 3 3 0 Phenylalanine zipper Gsf2 PF11055.3 EIE84109.1 - 0.074 11.5 0.6 0.089 11.2 0.4 1.1 1 0 0 1 1 1 0 Glucose signalling factor 2 DDE_1 PF03184.14 EIE84110.1 - 0.033 13.3 0.0 0.072 12.2 0.0 1.6 1 0 0 1 1 1 0 DDE superfamily endonuclease DUF3126 PF11324.3 EIE84110.1 - 0.065 12.9 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3126) UDG PF03167.14 EIE84112.1 - 4.4e-05 22.9 0.0 4.8e-05 22.8 0.0 1.0 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Pox_Ag35 PF03286.9 EIE84114.1 - 0.018 14.6 2.1 0.019 14.4 1.5 1.0 1 0 0 1 1 1 0 Pox virus Ag35 surface protein YABBY PF04690.8 EIE84114.1 - 0.21 11.8 2.2 0.24 11.6 1.5 1.1 1 0 0 1 1 1 0 YABBY protein VTC PF09359.5 EIE84114.1 - 0.22 10.5 4.4 0.22 10.4 3.1 1.1 1 0 0 1 1 1 0 VTC domain PMSI1 PF15322.1 EIE84114.1 - 0.24 10.4 3.7 0.26 10.3 2.6 1.0 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative SpoVR PF04293.8 EIE84114.1 - 0.28 9.4 6.6 0.3 9.4 4.6 1.0 1 0 0 1 1 1 0 SpoVR like protein G0-G1_switch_2 PF15103.1 EIE84114.1 - 0.49 10.6 6.1 0.58 10.4 4.2 1.1 1 0 0 1 1 1 0 G0/G1 switch protein 2 Rhabdo_ncap PF00945.13 EIE84114.1 - 0.62 8.5 3.0 0.58 8.6 2.1 1.0 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Het-C PF07217.6 EIE84114.1 - 0.77 7.8 4.4 0.73 7.9 3.0 1.0 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C EIIBC-GUT_N PF03612.9 EIE84114.1 - 1 8.9 3.5 1 8.9 2.4 1.0 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus EHN PF06441.7 EIE84114.1 - 1.5 8.7 6.2 1.7 8.5 4.3 1.0 1 0 0 1 1 1 0 Epoxide hydrolase N terminus DUF3381 PF11861.3 EIE84114.1 - 1.6 8.2 10.3 1.7 8.1 7.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) DUF4557 PF15101.1 EIE84114.1 - 1.7 8.4 13.1 1.8 8.3 9.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) OATP PF03137.15 EIE84114.1 - 2.2 6.2 4.0 2.3 6.1 2.8 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Spore_coat_CotO PF14153.1 EIE84114.1 - 2.9 7.3 14.0 3 7.2 9.7 1.0 1 0 0 1 1 1 0 Spore coat protein CotO DUF3154 PF11351.3 EIE84114.1 - 3.4 7.4 5.4 4.2 7.1 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3154) BAF1_ABF1 PF04684.8 EIE84114.1 - 4 6.1 17.6 3.8 6.2 12.2 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF1943 PF09172.6 EIE84114.1 - 5.3 5.8 7.0 5.5 5.7 4.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) Med15 PF09606.5 EIE84114.1 - 6.3 4.8 23.7 6.5 4.8 16.5 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Serinc PF03348.10 EIE84114.1 - 6.4 5.3 5.5 6.1 5.4 3.8 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) TMEM51 PF15345.1 EIE84114.1 - 7.2 6.2 8.1 7.3 6.2 5.6 1.0 1 0 0 1 1 1 0 Transmembrane protein 51 Peptidase_S15 PF02129.13 EIE84114.1 - 7.3 5.9 6.7 7.4 5.9 4.6 1.0 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) FPN1 PF06963.7 EIE84114.1 - 8.9 4.5 6.1 9 4.5 4.2 1.0 1 0 0 1 1 1 0 Ferroportin1 (FPN1) rve PF00665.21 EIE84120.1 - 2e-08 34.3 0.1 1.1e-06 28.7 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.5 EIE84120.1 - 6.1e-05 22.3 0.1 0.00016 20.9 0.1 1.8 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger RNase_H PF00075.19 EIE84120.1 - 0.065 13.5 0.0 0.12 12.6 0.0 1.6 1 1 0 1 1 1 0 RNase H KxDL PF10241.4 EIE84121.1 - 0.03 14.2 0.0 0.043 13.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein DUF3696 PF12476.3 EIE84122.1 - 0.096 12.6 1.4 0.21 11.5 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3696) HTH_Tnp_Tc3_2 PF01498.13 EIE84123.1 - 3e-07 30.3 1.0 6.1e-07 29.4 0.7 1.6 1 1 0 1 1 1 1 Transposase DDE_3 PF13358.1 EIE84125.1 - 4.9e-08 32.8 2.7 5e-08 32.8 0.7 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease Leader_Erm PF08253.6 EIE84126.1 - 0.33 10.4 0.3 0.33 10.4 0.2 2.1 2 0 0 2 2 2 0 Erm Leader peptide DUF2614 PF11023.3 EIE84126.1 - 0.53 10.0 3.2 0.63 9.8 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2614) HTH_Tnp_Tc3_2 PF01498.13 EIE84128.1 - 2.6e-08 33.8 0.7 5.1e-08 32.8 0.5 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.1 EIE84128.1 - 0.0018 19.0 0.1 1.4 9.7 0.0 2.4 2 0 0 2 2 2 2 Homeodomain-like domain HTH_29 PF13551.1 EIE84128.1 - 0.026 14.6 0.1 0.17 12.0 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn helix DUF4160 PF13711.1 EIE84128.1 - 0.035 13.9 1.1 0.16 11.8 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4160) MerR_1 PF13411.1 EIE84128.1 - 0.13 12.0 0.0 0.32 10.8 0.0 1.7 1 0 0 1 1 1 0 MerR HTH family regulatory protein HTH_Tnp_ISL3 PF13542.1 EIE84129.1 - 0.00017 20.6 0.1 0.00021 20.4 0.1 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_23 PF13384.1 EIE84129.1 - 0.0038 16.8 0.0 0.0043 16.6 0.0 1.1 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.1 EIE84129.1 - 0.005 16.8 0.0 0.0068 16.3 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_DeoR PF08220.7 EIE84129.1 - 0.11 11.9 0.1 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain Plant_tran PF04827.9 EIE84131.1 - 2e-29 102.4 0.1 2.7e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_4 PF13359.1 EIE84131.1 - 0.0002 20.9 0.4 0.00066 19.3 0.3 1.9 1 1 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EIE84132.1 - 5.8e-21 74.7 0.1 9.5e-21 74.0 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE84132.1 - 6.4e-19 67.7 0.8 6.4e-19 67.7 0.5 2.5 3 1 0 3 3 3 1 Transposase HTH_29 PF13551.1 EIE84132.1 - 3e-09 37.0 1.1 9.7e-09 35.3 0.6 1.9 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.1 EIE84132.1 - 2.6e-06 28.1 4.4 3.9e-05 24.3 0.1 3.9 4 1 1 5 5 5 1 Homeodomain-like domain HTH_23 PF13384.1 EIE84132.1 - 1.6e-05 24.3 0.1 0.0011 18.5 0.0 3.0 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.1 EIE84132.1 - 0.00065 19.6 0.1 0.012 15.6 0.0 2.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_21 PF13276.1 EIE84132.1 - 0.0016 18.4 0.0 0.014 15.3 0.0 2.5 2 0 0 2 2 2 1 HTH-like domain rve PF00665.21 EIE84132.1 - 0.0029 17.7 0.0 0.0086 16.1 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain FUR PF01475.14 EIE84132.1 - 0.0037 17.1 0.1 0.18 11.7 0.0 2.5 2 0 0 2 2 2 1 Ferric uptake regulator family HTH_7 PF02796.10 EIE84132.1 - 0.03 14.1 3.6 1.8 8.5 0.1 3.0 2 1 0 2 2 2 0 Helix-turn-helix domain of resolvase DUF4582 PF15189.1 EIE84133.1 - 0.052 12.7 0.0 0.078 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4582) UBN2_2 PF14227.1 EIE84133.1 - 0.13 11.8 0.0 0.37 10.3 0.0 1.7 1 1 0 1 1 1 0 gag-polypeptide of LTR copia-type CVNH PF08881.5 EIE84135.1 - 0.11 12.7 0.1 0.17 12.1 0.1 1.3 1 1 0 1 1 1 0 CVNH domain DDE_3 PF13358.1 EIE84136.1 - 5.2e-22 78.1 0.5 8.6e-22 77.4 0.1 1.6 2 0 0 2 2 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE84136.1 - 1.6e-15 56.8 1.4 7.9e-15 54.6 0.1 2.6 3 0 0 3 3 3 1 Transposase HTH_29 PF13551.1 EIE84136.1 - 1.1e-06 28.7 0.2 4.7e-06 26.7 0.1 2.0 2 0 0 2 2 2 1 Winged helix-turn helix HTH_38 PF13936.1 EIE84136.1 - 1e-05 24.9 0.0 2.3e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.1 EIE84136.1 - 8.8e-05 22.0 0.0 0.0017 17.9 0.0 2.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.1 EIE84136.1 - 0.00013 22.6 3.2 0.021 15.6 0.1 3.9 3 1 1 4 4 4 1 Homeodomain-like domain HTH_7 PF02796.10 EIE84136.1 - 0.00068 19.4 1.4 0.02 14.7 0.0 2.7 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase HTH_28 PF13518.1 EIE84136.1 - 0.00079 19.3 0.0 0.0042 17.0 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_21 PF13276.1 EIE84136.1 - 0.0012 18.7 0.1 0.1 12.6 0.0 2.9 3 0 0 3 3 3 1 HTH-like domain rve PF00665.21 EIE84136.1 - 0.0017 18.4 0.0 0.004 17.2 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Sigma70_r4_2 PF08281.7 EIE84136.1 - 0.0033 16.8 1.1 0.022 14.2 0.0 2.8 4 0 0 4 4 4 1 Sigma-70, region 4 HTH_Tnp_4 PF13613.1 EIE84136.1 - 0.03 13.8 0.3 0.073 12.6 0.0 1.7 2 0 0 2 2 1 0 Helix-turn-helix of DDE superfamily endonuclease LacI PF00356.16 EIE84136.1 - 0.06 12.9 1.0 1.7 8.3 0.1 2.6 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family Sigma70_r4 PF04545.11 EIE84136.1 - 0.064 12.5 0.2 0.48 9.7 0.0 2.5 4 0 0 4 4 4 0 Sigma-70, region 4 CPSase_L_D3 PF02787.14 EIE84136.1 - 0.071 12.8 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain HTH_Tnp_ISL3 PF13542.1 EIE84136.1 - 0.65 9.2 3.7 17 4.6 0.1 3.0 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 DDE_3 PF13358.1 EIE84137.1 - 2.6e-13 49.9 0.1 3.9e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE84137.1 - 1.7e-12 47.2 0.3 4.2e-12 45.9 0.2 1.7 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.1 EIE84137.1 - 3e-06 27.3 0.6 5.6e-06 26.4 0.4 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EIE84137.1 - 3.4e-05 23.3 0.6 0.00019 20.9 0.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_7 PF02796.10 EIE84137.1 - 0.0042 16.9 0.4 0.091 12.6 0.1 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase DUF2110 PF09883.4 EIE84137.1 - 0.02 14.4 0.4 0.15 11.6 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2110) HTH_28 PF13518.1 EIE84137.1 - 0.022 14.7 0.6 0.075 13.0 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain SecD-TM1 PF13721.1 EIE84137.1 - 0.044 14.0 0.3 0.081 13.1 0.2 1.4 1 0 0 1 1 1 0 SecD export protein N-terminal TM region HTH_Tnp_IS630 PF01710.11 EIE84137.1 - 0.049 13.3 0.3 0.15 11.7 0.0 2.0 2 0 0 2 2 2 0 Transposase rve PF00665.21 EIE84137.1 - 0.081 13.0 0.0 0.23 11.5 0.0 1.9 1 1 0 1 1 1 0 Integrase core domain DDE_3 PF13358.1 EIE84138.1 - 1.6e-09 37.6 2.1 3e-09 36.7 0.5 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE84139.1 - 2.7e-06 27.3 0.9 2.7e-06 27.3 0.6 1.9 1 1 1 2 2 2 1 Transposase Sigma70_r1_2 PF00140.15 EIE84139.1 - 0.0019 17.8 0.1 0.0033 17.0 0.0 1.4 1 0 0 1 1 1 1 Sigma-70 factor, region 1.2 Retrotrans_gag PF03732.12 EIE84140.1 - 0.0025 17.8 1.5 0.0047 16.9 0.1 2.2 3 0 0 3 3 3 1 Retrotransposon gag protein zf-CCHC PF00098.18 EIE84140.1 - 0.033 14.1 1.2 0.058 13.3 0.8 1.4 1 0 0 1 1 1 0 Zinc knuckle gag-asp_proteas PF13975.1 EIE84141.1 - 1.6e-08 34.2 0.0 3.4e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EIE84141.1 - 4.3e-06 27.1 0.0 2.8e-05 24.5 0.1 2.1 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.5 EIE84141.1 - 0.0067 15.9 0.0 0.035 13.6 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease MucB_RseB PF03888.9 EIE84141.1 - 0.015 14.3 0.0 0.029 13.4 0.0 1.4 1 0 0 1 1 1 0 MucB/RseB family RVP_2 PF08284.6 EIE84141.1 - 0.13 12.1 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Peptidase_M9_N PF08453.5 EIE84142.1 - 0.0031 16.8 0.1 0.0073 15.6 0.1 1.6 1 1 1 2 2 2 1 Peptidase family M9 N-terminal Myb_DNA-bind_5 PF13873.1 EIE84142.1 - 0.047 13.5 0.7 0.18 11.7 0.0 2.2 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain TFR_dimer PF04253.10 EIE84142.1 - 0.062 12.8 0.6 0.81 9.2 0.1 2.2 2 0 0 2 2 2 0 Transferrin receptor-like dimerisation domain DAO PF01266.19 EIE84145.1 - 8e-53 179.6 0.0 1e-52 179.2 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EIE84145.1 - 1.3e-08 34.1 1.1 0.0011 17.9 0.2 2.1 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.2 EIE84145.1 - 1.1e-07 31.3 0.8 2.4e-05 23.6 0.2 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EIE84145.1 - 0.0006 18.9 0.6 0.0081 15.2 0.4 2.1 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EIE84145.1 - 0.0077 16.1 0.2 0.032 14.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EIE84145.1 - 0.011 14.5 0.3 0.28 9.9 0.1 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.12 EIE84145.1 - 0.017 14.1 1.0 0.14 11.2 0.1 2.2 2 0 0 2 2 2 0 Thi4 family NAD_binding_8 PF13450.1 EIE84145.1 - 0.031 14.2 0.7 0.13 12.3 0.5 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.13 EIE84145.1 - 0.052 13.1 0.1 0.11 12.1 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.22 EIE84145.1 - 0.11 12.9 1.0 0.82 10.1 0.2 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF3437 PF11919.3 EIE84146.1 - 3.4e-33 113.2 0.6 1e-31 108.4 0.0 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF3437) HEAT PF02985.17 EIE84146.1 - 0.00013 21.7 1.9 1.1 9.5 0.0 5.3 6 0 0 6 6 6 2 HEAT repeat Ras PF00071.17 EIE84147.1 - 2.7e-53 179.6 0.0 3e-53 179.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIE84147.1 - 1.3e-15 57.9 0.0 1.9e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIE84147.1 - 6.5e-07 28.7 0.0 9e-07 28.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Metallophos PF00149.23 EIE84148.1 - 0.0027 17.1 0.0 0.0028 17.0 0.0 1.0 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Thioredoxin PF00085.15 EIE84149.1 - 1.6e-56 188.3 0.3 8.4e-26 89.6 0.2 4.3 4 0 0 4 4 4 4 Thioredoxin Thioredoxin_6 PF13848.1 EIE84149.1 - 7.1e-38 130.2 5.0 2.2e-26 92.8 0.6 3.2 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_2 PF13098.1 EIE84149.1 - 3.6e-11 43.2 1.5 0.0051 16.9 0.1 5.8 3 2 1 4 4 4 3 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EIE84149.1 - 2.6e-09 37.0 0.8 0.053 13.6 0.1 5.4 3 1 1 4 4 4 2 Thioredoxin-like Thioredoxin_7 PF13899.1 EIE84149.1 - 2.7e-06 27.2 0.3 0.1 12.6 0.0 3.2 3 0 0 3 3 3 2 Thioredoxin-like ERp29_N PF07912.8 EIE84149.1 - 0.00017 21.4 0.1 0.43 10.5 0.0 3.3 3 0 0 3 3 3 2 ERp29, N-terminal domain Thioredoxin_3 PF13192.1 EIE84149.1 - 0.0041 16.9 0.1 0.74 9.6 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin domain MPC PF03650.8 EIE84150.1 - 4.5e-37 126.6 0.5 4.9e-37 126.5 0.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) Chitin_synth_1 PF01644.12 EIE84151.1 - 2.3e-44 151.0 0.0 3.6e-44 150.4 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.10 EIE84151.1 - 1.7e-13 49.8 1.2 6.4e-10 38.0 0.0 2.1 2 0 0 2 2 2 2 Chitin synthase DUF998 PF06197.8 EIE84151.1 - 0.0086 15.3 5.4 1.8 7.8 0.0 3.1 2 1 1 3 3 3 3 Protein of unknown function (DUF998) SNAP PF14938.1 EIE84152.1 - 1.2e-25 90.2 13.4 1.8e-25 89.6 9.3 1.2 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_11 PF13414.1 EIE84152.1 - 1.2e-05 24.9 15.3 0.04 13.5 5.6 3.7 1 1 2 3 3 3 3 TPR repeat TPR_12 PF13424.1 EIE84152.1 - 0.001 18.9 12.6 0.17 11.8 3.7 3.8 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 EIE84152.1 - 0.0014 18.2 13.1 7.8 6.5 0.0 6.5 3 3 2 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 EIE84152.1 - 0.008 16.7 8.6 3 8.7 0.2 5.3 3 1 3 6 6 6 1 Tetratricopeptide repeat TOM20_plant PF06552.7 EIE84152.1 - 0.032 13.8 2.7 0.11 12.0 0.8 2.3 1 1 1 2 2 2 0 Plant specific mitochondrial import receptor subunit TOM20 TPR_16 PF13432.1 EIE84152.1 - 0.072 13.7 14.3 18 6.1 4.7 4.2 3 1 1 4 4 3 0 Tetratricopeptide repeat Clathrin PF00637.15 EIE84152.1 - 0.11 12.0 5.8 17 4.9 0.2 3.7 1 1 2 3 3 3 0 Region in Clathrin and VPS TPR_1 PF00515.23 EIE84152.1 - 0.22 11.2 15.8 3.5 7.4 0.2 5.3 4 2 2 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.1 EIE84152.1 - 0.37 11.3 12.8 38 5.0 0.0 5.6 3 2 2 5 5 5 0 Tetratricopeptide repeat MIT PF04212.13 EIE84152.1 - 0.73 9.7 15.2 4.4 7.2 0.3 4.8 2 2 2 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_2 PF07719.12 EIE84152.1 - 1.9 8.6 16.8 4.8 7.3 0.2 5.9 3 3 4 7 7 7 0 Tetratricopeptide repeat TPR_8 PF13181.1 EIE84152.1 - 3.4 7.6 12.6 51 3.9 0.1 5.3 3 3 3 6 6 6 0 Tetratricopeptide repeat LAG1-DNAbind PF09271.6 EIE84153.1 - 2.3e-23 83.2 2.4 8.8e-13 48.9 0.0 2.8 1 1 1 2 2 2 2 LAG1, DNA binding BTD PF09270.5 EIE84153.1 - 8.9e-22 77.5 0.0 2e-21 76.3 0.0 1.7 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain Vps51 PF08700.6 EIE84154.1 - 1.5e-13 50.3 0.0 4.3e-13 48.8 0.0 1.8 1 0 0 1 1 1 1 Vps51/Vps67 Glyco_hydro_32N PF00251.15 EIE84154.1 - 0.015 14.6 0.0 0.071 12.4 0.0 1.9 2 0 0 2 2 2 0 Glycosyl hydrolases family 32 N-terminal domain DUF3291 PF11695.3 EIE84154.1 - 0.049 13.0 0.0 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3291) Sec5 PF15469.1 EIE84154.1 - 0.17 11.5 3.6 0.11 12.2 0.2 2.4 3 0 0 3 3 3 0 Exocyst complex component Sec5 Abhydrolase_6 PF12697.2 EIE84155.1 - 2.5e-11 43.8 2.7 5.2e-11 42.8 1.9 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIE84155.1 - 4.7e-07 29.6 0.4 6.8e-07 29.1 0.3 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIE84155.1 - 0.006 16.1 0.0 0.0079 15.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold ERG4_ERG24 PF01222.12 EIE84156.1 - 6.6e-120 400.5 15.1 6.2e-66 222.7 2.2 2.0 1 1 1 2 2 2 2 Ergosterol biosynthesis ERG4/ERG24 family PEMT PF04191.8 EIE84156.1 - 0.044 13.8 0.0 0.044 13.8 0.0 3.3 4 1 1 5 5 5 0 Phospholipid methyltransferase MFS_1 PF07690.11 EIE84158.1 - 2.1e-31 108.9 53.0 6.9e-22 77.6 18.5 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIE84158.1 - 6.6e-10 38.1 18.6 6.6e-10 38.1 12.9 2.2 1 1 0 2 2 2 1 Sugar (and other) transporter Pmp3 PF01679.12 EIE84158.1 - 0.015 14.9 1.8 0.015 14.9 1.2 2.9 3 0 0 3 3 3 0 Proteolipid membrane potential modulator Corona_S2 PF01601.11 EIE84158.1 - 6.9 4.6 9.9 1.3 7.0 1.5 2.2 2 0 0 2 2 2 0 Coronavirus S2 glycoprotein Band_7 PF01145.20 EIE84159.1 - 1.8e-23 83.3 3.6 2.6e-23 82.8 2.5 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family zf-CCCH PF00642.19 EIE84160.1 - 3.5e-08 32.9 18.0 0.003 17.1 2.4 3.5 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCHC PF00098.18 EIE84160.1 - 1.3e-05 24.8 2.6 1.3e-05 24.8 1.8 3.2 3 0 0 3 3 3 1 Zinc knuckle FCP1_C PF09309.5 EIE84160.1 - 0.04 13.2 8.7 0.061 12.6 6.0 1.2 1 0 0 1 1 1 0 FCP1, C-terminal Suf PF05843.9 EIE84160.1 - 0.056 13.1 7.3 0.061 13.0 5.1 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) zf-CCCH_2 PF14608.1 EIE84160.1 - 0.12 12.3 24.1 0.72 9.9 1.4 4.6 4 1 0 4 4 4 0 Zinc finger C-x8-C-x5-C-x3-H type Herpes_DNAp_acc PF04929.7 EIE84160.1 - 1.1 8.2 6.4 1.4 7.8 4.4 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor PAT1 PF09770.4 EIE84160.1 - 1.3 7.1 27.6 1.4 7.1 19.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4407 PF14362.1 EIE84160.1 - 1.7 7.5 5.8 2 7.2 4.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4106 PF13388.1 EIE84160.1 - 1.7 7.5 16.7 1.9 7.3 11.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Pex16 PF08610.5 EIE84160.1 - 2.3 7.1 8.3 2.9 6.8 5.7 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) BAF1_ABF1 PF04684.8 EIE84160.1 - 3.3 6.4 24.9 4.2 6.0 17.3 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Band_3_cyto PF07565.8 EIE84160.1 - 3.5 7.0 7.1 4.7 6.6 4.9 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain FimP PF09766.4 EIE84160.1 - 3.9 6.4 16.7 5.4 5.9 11.6 1.1 1 0 0 1 1 1 0 Fms-interacting protein Herpes_LMP2 PF07415.6 EIE84160.1 - 4.5 5.7 5.6 5.5 5.4 3.9 1.1 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein Pex14_N PF04695.8 EIE84160.1 - 5 7.1 19.5 7.8 6.5 13.5 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ndc1_Nup PF09531.5 EIE84160.1 - 6.2 5.1 6.8 7.1 4.9 4.7 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Per1 PF04080.8 EIE84161.1 - 4.3e-93 311.6 12.7 7.3e-93 310.8 8.8 1.4 1 0 0 1 1 1 1 Per1-like NAD_binding_8 PF13450.1 EIE84161.1 - 4.2e-11 42.6 0.0 1.1e-10 41.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EIE84161.1 - 4.9e-06 25.6 0.0 1.4e-05 24.1 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EIE84161.1 - 0.00018 21.4 0.0 0.012 15.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EIE84161.1 - 0.00019 21.2 0.5 0.1 12.3 0.0 2.6 3 0 0 3 3 3 2 FAD-NAD(P)-binding HI0933_like PF03486.9 EIE84161.1 - 0.00092 17.7 0.1 0.15 10.4 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.19 EIE84161.1 - 0.0015 17.4 0.1 0.0023 16.8 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EIE84161.1 - 0.0034 16.5 0.0 0.0056 15.8 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 EIE84161.1 - 0.0048 16.9 0.0 1.7 8.6 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EIE84161.1 - 0.074 12.0 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.17 EIE84161.1 - 0.12 11.1 0.2 0.7 8.6 0.0 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A MS_channel PF00924.13 EIE84163.1 - 6.1e-12 45.2 5.7 8.1e-12 44.9 4.0 1.1 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_6 PF13405.1 EIE84163.1 - 5.4e-05 22.7 0.0 0.00012 21.6 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.27 EIE84163.1 - 0.0002 20.4 0.0 0.00039 19.5 0.0 1.5 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.1 EIE84163.1 - 0.00053 19.2 0.0 0.0013 17.9 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 EIE84163.1 - 0.013 15.6 0.0 0.021 14.9 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain pair SH3_1 PF00018.23 EIE84164.1 - 1.5e-29 101.1 0.0 1.3e-15 56.5 0.0 2.6 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 EIE84164.1 - 1.5e-19 69.2 0.0 3.3e-10 39.3 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.12 EIE84164.1 - 8.8e-19 66.7 0.3 3e-12 45.8 0.0 3.0 3 0 0 3 3 3 2 Variant SH3 domain PX PF00787.19 EIE84164.1 - 9.4e-08 31.8 0.0 2e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 PX domain PB1 PF00564.19 EIE84164.1 - 0.0016 18.0 0.0 0.0035 16.9 0.0 1.6 1 0 0 1 1 1 1 PB1 domain NAD_Gly3P_dh_C PF07479.9 EIE84166.1 - 8.1e-55 184.6 0.1 1.1e-54 184.2 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.18 EIE84166.1 - 4.3e-52 175.9 0.0 8e-52 175.1 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Rpn3_C PF08375.6 EIE84168.1 - 1.5e-27 95.7 1.9 1.5e-27 95.7 1.3 2.7 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal PCI PF01399.22 EIE84168.1 - 4e-21 75.3 0.4 4.8e-20 71.8 0.0 2.7 3 0 0 3 3 3 1 PCI domain TPR_12 PF13424.1 EIE84168.1 - 0.033 14.1 12.7 0.067 13.1 3.9 2.9 1 1 2 3 3 3 0 Tetratricopeptide repeat DUF2496 PF10689.4 EIE84168.1 - 0.056 13.0 2.0 2 8.1 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2496) TPR_2 PF07719.12 EIE84168.1 - 0.36 10.8 3.8 0.2 11.6 0.5 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3482 PF11981.3 EIE84170.1 - 0.36 10.0 7.7 0.22 10.7 3.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3482) MHYT PF03707.11 EIE84171.1 - 1.3e-15 57.2 19.2 1.8e-05 24.7 1.6 4.4 4 0 0 4 4 4 3 Bacterial signalling protein N terminal repeat Pec_lyase_N PF04431.8 EIE84173.1 - 0.059 13.4 0.1 0.15 12.1 0.1 1.6 1 0 0 1 1 1 0 Pectate lyase, N terminus Ribonuc_red_lgC PF02867.10 EIE84174.1 - 1.1e-214 713.9 0.0 1.5e-214 713.5 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 EIE84174.1 - 3.8e-23 81.0 0.0 8.4e-23 79.9 0.0 1.6 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 EIE84174.1 - 1.7e-07 31.5 0.1 6.2e-07 29.7 0.0 2.0 1 0 0 1 1 1 1 ATP cone domain NRDD PF13597.1 EIE84174.1 - 0.034 12.2 0.0 0.05 11.6 0.0 1.2 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase G-gamma PF00631.17 EIE84174.1 - 0.041 13.6 0.3 10 5.9 0.0 2.7 2 0 0 2 2 2 0 GGL domain YniB PF14002.1 EIE84175.1 - 0.81 9.1 4.1 1.1 8.6 2.8 1.4 1 1 0 1 1 1 0 YniB-like protein DUF740 PF05340.7 EIE84175.1 - 1.6 7.0 4.6 1.6 6.9 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF740) Merozoite_SPAM PF07133.6 EIE84175.1 - 6.5 6.6 16.5 2.4 8.0 8.2 2.0 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) PI3_PI4_kinase PF00454.22 EIE84176.1 - 1.2e-29 103.4 0.1 3e-29 102.1 0.1 1.7 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.3 EIE84176.1 - 3.4e-12 45.9 0.0 7.6e-12 44.7 0.0 1.6 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 PI3Ka PF00613.15 EIE84176.1 - 1.5e-06 27.5 0.1 4.1e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) IPK PF03770.11 EIE84177.1 - 1.6e-20 73.5 0.3 2.2e-20 73.1 0.2 1.1 1 0 0 1 1 1 1 Inositol polyphosphate kinase SET PF00856.23 EIE84178.1 - 2.7e-13 50.5 1.4 4.2e-11 43.4 1.0 2.9 1 1 0 1 1 1 1 SET domain HTH_21 PF13276.1 EIE84178.1 - 0.00093 19.1 0.0 0.0035 17.3 0.0 2.0 2 0 0 2 2 2 1 HTH-like domain zf-MYND PF01753.13 EIE84178.1 - 0.014 15.2 15.6 0.014 15.2 10.8 2.5 2 0 0 2 2 2 0 MYND finger Ribosomal_L30 PF00327.15 EIE84179.1 - 9.6e-08 31.5 0.1 2e-07 30.4 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.7 EIE84179.1 - 1.6e-06 28.0 19.1 1.6e-06 28.0 13.2 2.1 2 1 0 2 2 2 1 Ribosomal L30 N-terminal domain Acyltransferase PF01553.16 EIE84180.1 - 0.13 11.6 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 Acyltransferase RINT1_TIP1 PF04437.8 EIE84181.1 - 0.012 14.1 0.4 0.014 13.9 0.3 1.0 1 0 0 1 1 1 0 RINT-1 / TIP-1 family DUF2399 PF09664.5 EIE84181.1 - 0.064 13.1 0.4 0.068 13.0 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2399) Med31 PF05669.7 EIE84181.1 - 0.094 12.4 1.4 2.1 8.1 0.0 2.0 1 1 1 2 2 2 0 SOH1 Pkinase PF00069.20 EIE84182.1 - 4.5e-49 166.9 0.1 5.3e-47 160.1 0.1 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE84182.1 - 4.2e-20 71.9 0.0 1.3e-19 70.3 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE84182.1 - 2.6e-09 36.4 0.0 3.3e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EIE84182.1 - 8.7e-08 31.4 0.1 1.3e-07 30.9 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EIE84182.1 - 6.4e-05 22.3 0.0 0.0001 21.7 0.0 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EIE84182.1 - 6.8e-05 22.7 0.0 9.3e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EIE84182.1 - 0.0058 16.2 1.0 0.012 15.2 0.5 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase Cellulase PF00150.13 EIE84183.1 - 4.7e-09 35.8 2.1 9.4e-09 34.8 1.5 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF2963 PF11178.3 EIE84183.1 - 1 8.8 5.1 5.4 6.5 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2963) TMCO5 PF14992.1 EIE84184.1 - 0.0018 17.5 8.9 0.0024 17.0 6.2 1.2 1 0 0 1 1 1 1 TMCO5 family Reo_sigmaC PF04582.7 EIE84184.1 - 0.02 14.1 1.3 0.026 13.7 0.9 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Striatin PF08232.7 EIE84184.1 - 0.14 12.4 11.0 0.12 12.6 0.8 2.5 1 1 0 2 2 2 0 Striatin family Atg14 PF10186.4 EIE84184.1 - 0.17 10.8 21.7 0.0092 14.9 5.0 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 LPP PF04728.8 EIE84184.1 - 0.19 11.5 4.6 6.6 6.6 1.0 3.3 2 1 1 3 3 3 0 Lipoprotein leucine-zipper DUF77 PF01910.12 EIE84184.1 - 0.28 10.9 1.7 7.4 6.3 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function DUF77 Bacillus_HBL PF05791.6 EIE84184.1 - 0.38 10.1 9.6 0.073 12.4 1.0 2.5 1 1 2 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) NPV_P10 PF05531.7 EIE84184.1 - 0.42 10.9 8.2 1.1 9.5 1.2 2.7 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein FUSC PF04632.7 EIE84184.1 - 0.45 8.8 11.9 0.56 8.5 8.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Microtub_assoc PF07989.6 EIE84184.1 - 0.63 9.8 12.1 0.56 10.0 0.6 3.5 2 2 1 4 4 4 0 Microtubule associated Baculo_PEP_C PF04513.7 EIE84184.1 - 0.84 9.4 10.1 0.87 9.4 2.2 2.5 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1465 PF07323.7 EIE84184.1 - 0.98 8.9 9.0 0.1 12.1 1.5 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1465) TMF_DNA_bd PF12329.3 EIE84184.1 - 1.3 8.8 15.5 0.097 12.4 2.7 3.0 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Med9 PF07544.8 EIE84184.1 - 1.6 8.5 11.1 0.056 13.1 1.4 2.7 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 ADIP PF11559.3 EIE84184.1 - 2.7 7.8 19.5 1.1 9.1 3.7 2.7 1 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Uds1 PF15456.1 EIE84185.1 - 2.5e-10 40.4 0.1 3.8e-10 39.8 0.1 1.2 1 0 0 1 1 1 1 Up-regulated During Septation HALZ PF02183.13 EIE84185.1 - 0.086 12.5 0.1 0.15 11.8 0.1 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper Zw10 PF06248.8 EIE84188.1 - 3.4e-25 88.2 0.0 8.3e-12 44.0 0.0 2.1 1 1 1 2 2 2 2 Centromere/kinetochore Zw10 Dsl1_C PF11989.3 EIE84188.1 - 5.4e-06 25.7 0.1 1.5e-05 24.3 0.1 1.7 1 0 0 1 1 1 1 Retrograde transport protein Dsl1 C terminal PT PF04886.7 EIE84188.1 - 0.01 15.1 20.8 0.022 14.0 14.4 1.5 1 0 0 1 1 1 0 PT repeat TALPID3 PF15324.1 EIE84188.1 - 0.16 9.2 5.7 0.23 8.7 4.0 1.1 1 0 0 1 1 1 0 Hedgehog signalling target Ebola_NP PF05505.7 EIE84188.1 - 9.5 4.1 8.8 15 3.5 6.1 1.2 1 0 0 1 1 1 0 Ebola nucleoprotein WD40 PF00400.27 EIE84189.1 - 0.049 13.5 0.0 19 5.3 0.0 3.6 4 0 0 4 4 4 0 WD domain, G-beta repeat GTP_EFTU_D3 PF03143.12 EIE84192.1 - 7.5e-05 22.8 0.0 9.8e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain Not3 PF04065.10 EIE84194.1 - 2.1e-48 164.6 12.0 2.1e-48 164.6 8.3 2.1 3 0 0 3 3 3 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 EIE84194.1 - 5.1e-45 152.6 10.4 1.8e-44 150.8 7.2 2.0 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family DUF1192 PF06698.6 EIE84194.1 - 0.0061 16.3 0.2 0.02 14.7 0.1 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1192) DUF2373 PF10180.4 EIE84194.1 - 0.11 12.0 3.6 0.27 10.8 2.5 1.7 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) DUF4613 PF15390.1 EIE84194.1 - 6.6 4.7 8.5 0.11 10.6 1.4 1.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4613) FtsK_SpoIIIE PF01580.13 EIE84195.1 - 0.041 13.3 0.1 0.066 12.6 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family TMF_TATA_bd PF12325.3 EIE84195.1 - 0.047 13.4 2.7 0.11 12.1 0.8 2.4 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding YPEB PF14620.1 EIE84195.1 - 0.084 11.8 2.6 0.12 11.3 1.8 1.2 1 0 0 1 1 1 0 YpeB sporulation TMF_DNA_bd PF12329.3 EIE84195.1 - 0.093 12.5 2.6 0.29 10.9 1.8 1.9 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF2296 PF10058.4 EIE84195.1 - 0.16 11.7 1.5 0.38 10.5 1.0 1.7 1 0 0 1 1 1 0 Predicted integral membrane metal-binding protein (DUF2296) TEX13 PF15186.1 EIE84195.1 - 0.55 9.8 4.4 0.13 11.7 0.6 1.7 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family IncA PF04156.9 EIE84195.1 - 0.71 9.4 5.7 0.33 10.5 1.9 1.8 1 1 1 2 2 2 0 IncA protein Ima1_N PF09779.4 EIE84195.1 - 1.4 9.3 6.2 0.67 10.4 0.9 2.8 2 1 1 3 3 3 0 Ima1 N-terminal domain ADK_lid PF05191.9 EIE84195.1 - 5.5 6.7 6.1 9.4 6.0 0.3 2.2 1 1 1 2 2 2 0 Adenylate kinase, active site lid HTH_Tnp_Tc3_2 PF01498.13 EIE84196.1 - 1.6e-16 60.0 1.1 3.5e-16 58.9 0.8 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.1 EIE84196.1 - 2.9e-16 59.5 0.0 5e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 EIE84196.1 - 2.3e-08 34.1 0.4 3.6e-07 30.3 0.0 2.7 3 0 0 3 3 3 1 Winged helix-turn helix HTH_23 PF13384.1 EIE84196.1 - 0.00016 21.2 0.1 0.00061 19.3 0.0 2.0 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.1 EIE84196.1 - 0.0018 18.2 0.0 0.0062 16.5 0.0 2.0 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_17 PF12728.2 EIE84196.1 - 0.0074 16.5 0.6 0.29 11.3 0.0 3.0 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_24 PF13412.1 EIE84196.1 - 0.011 15.1 0.0 0.14 11.5 0.0 2.5 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding HTH_38 PF13936.1 EIE84196.1 - 0.012 15.1 0.0 0.036 13.6 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_7 PF02796.10 EIE84196.1 - 0.046 13.5 0.4 1 9.2 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase SpoIIID PF12116.3 EIE84196.1 - 0.046 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Stage III sporulation protein D HTH_IclR PF09339.5 EIE84196.1 - 0.049 13.2 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain MerR PF00376.18 EIE84196.1 - 0.07 12.6 0.3 7.2 6.2 0.0 3.0 3 0 0 3 3 3 0 MerR family regulatory protein Ribosomal_L12 PF00542.14 EIE84197.1 - 9.5e-22 76.7 12.7 1.6e-21 76.0 7.2 2.0 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain DUF2267 PF10025.4 EIE84197.1 - 0.0036 17.3 0.2 0.0097 15.9 0.1 1.8 1 1 1 2 2 2 1 Uncharacterized conserved protein (DUF2267) Ribosomal_60s PF00428.14 EIE84197.1 - 0.93 9.9 11.6 0.15 12.4 2.9 2.4 1 1 1 2 2 2 0 60s Acidic ribosomal protein WW PF00397.21 EIE84198.1 - 4.1e-09 36.1 0.3 8.8e-09 35.0 0.2 1.6 1 0 0 1 1 1 1 WW domain HSP70 PF00012.15 EIE84203.1 - 9.9e-08 30.3 0.0 4.2e-06 24.9 0.0 2.1 2 0 0 2 2 2 2 Hsp70 protein BcrAD_BadFG PF01869.15 EIE84203.1 - 0.065 12.5 0.1 0.14 11.4 0.0 1.6 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family UQ_con PF00179.21 EIE84204.1 - 3.9e-15 55.5 0.5 4.7e-15 55.2 0.4 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme zf-CCCH PF00642.19 EIE84205.1 - 5e-07 29.2 6.0 2.1e-06 27.2 0.8 3.0 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Peptidase_M3 PF01432.15 EIE84206.1 - 2.3e-146 488.4 1.6 4.7e-146 487.4 1.1 1.4 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M91 PF14891.1 EIE84206.1 - 0.034 14.2 0.3 0.087 12.8 0.2 1.6 1 0 0 1 1 1 0 Effector protein EXS PF03124.9 EIE84207.1 - 3.4e-25 88.8 11.0 4e-25 88.5 7.7 1.1 1 0 0 1 1 1 1 EXS family MTP18 PF10558.4 EIE84210.1 - 2.1e-54 183.4 0.2 2.6e-54 183.1 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) Orn_DAP_Arg_deC PF00278.17 EIE84210.1 - 0.073 12.7 0.0 0.093 12.4 0.0 1.3 1 1 0 1 1 1 0 Pyridoxal-dependent decarboxylase, C-terminal sheet domain zf-C2H2 PF00096.21 EIE84211.1 - 8.4e-11 41.5 9.4 7.4e-05 22.8 0.4 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIE84211.1 - 3.8e-09 36.3 15.9 1e-06 28.7 0.1 3.5 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 EIE84211.1 - 3.1e-06 27.1 15.4 0.00073 19.6 0.3 2.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EIE84211.1 - 0.0031 17.5 0.7 0.29 11.3 0.3 2.8 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EIE84211.1 - 0.0049 16.7 1.1 0.49 10.3 0.4 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger Zn-ribbon_8 PF09723.5 EIE84211.1 - 0.065 13.1 0.4 6.9 6.7 0.0 2.5 2 0 0 2 2 2 0 Zinc ribbon domain zf-met PF12874.2 EIE84211.1 - 0.091 13.0 2.1 0.42 10.8 0.4 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.1 EIE84211.1 - 0.27 11.5 6.6 1.8 8.9 1.5 2.7 2 0 0 2 2 2 0 C2H2-type zinc-finger domain DUF4618 PF15397.1 EIE84212.1 - 0.017 14.4 3.0 0.017 14.4 2.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) DUF2959 PF11172.3 EIE84212.1 - 0.053 13.2 1.6 3.2 7.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2959) DUF2951 PF11166.3 EIE84212.1 - 0.33 10.8 5.4 0.17 11.7 1.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2951) BRE1 PF08647.6 EIE84212.1 - 0.36 10.8 6.6 0.18 11.8 2.2 1.9 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase CENP-F_leu_zip PF10473.4 EIE84212.1 - 1.1 9.1 11.1 1.4 8.7 7.7 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.7 EIE84212.1 - 1.5 8.5 8.2 0.27 10.9 1.6 2.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Cast PF10174.4 EIE84212.1 - 1.6 6.7 10.3 1.8 6.5 7.2 1.0 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone DUF972 PF06156.8 EIE84212.1 - 1.6 9.0 8.4 13 6.1 5.8 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Ribonuc_L-PSP PF01042.16 EIE84213.1 - 3.7e-46 155.7 0.4 4.3e-46 155.6 0.3 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP HA2 PF04408.18 EIE84214.1 - 5.7e-29 100.1 0.1 1.7e-28 98.6 0.1 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EIE84214.1 - 1.4e-27 95.7 0.1 1.4e-27 95.7 0.1 1.9 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EIE84214.1 - 6.8e-11 41.8 0.0 2.2e-10 40.2 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EIE84214.1 - 2.7e-08 33.4 0.1 5.7e-08 32.4 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EIE84214.1 - 6.9e-06 26.2 0.0 2.7e-05 24.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 EIE84214.1 - 0.0022 17.4 0.1 0.005 16.3 0.0 1.6 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain PhoH PF02562.11 EIE84214.1 - 0.011 14.9 0.1 0.04 13.1 0.0 1.9 3 0 0 3 3 3 0 PhoH-like protein ResIII PF04851.10 EIE84214.1 - 0.013 15.3 0.0 6.3 6.5 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit T2SE PF00437.15 EIE84214.1 - 0.033 13.1 0.0 0.064 12.1 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.1 EIE84214.1 - 0.041 13.8 0.0 0.09 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.1 EIE84214.1 - 0.044 13.3 0.0 0.088 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EIE84214.1 - 0.045 14.0 0.1 0.19 12.0 0.1 2.1 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 EIE84214.1 - 0.12 11.8 0.0 0.3 10.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain GDE_N PF12439.3 EIE84215.1 - 0.016 14.4 0.1 0.027 13.7 0.0 1.3 1 0 0 1 1 1 0 Glycogen debranching enzyme N terminal RhoGAP PF00620.22 EIE84216.1 - 7.7e-09 35.3 0.1 1.7e-08 34.2 0.0 1.6 2 0 0 2 2 2 1 RhoGAP domain SH3_1 PF00018.23 EIE84217.1 - 6.7e-13 47.8 1.2 7.1e-13 47.7 0.8 1.0 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EIE84217.1 - 2.6e-11 42.9 0.5 2.8e-11 42.8 0.4 1.0 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EIE84217.1 - 8.9e-09 34.7 0.1 9.2e-09 34.6 0.1 1.0 1 0 0 1 1 1 1 Variant SH3 domain DUF727 PF05303.7 EIE84218.1 - 1.6e-11 43.9 0.0 2.3e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF727) F-box-like PF12937.2 EIE84219.1 - 9.9e-06 25.1 0.2 2e-05 24.2 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIE84219.1 - 9.7e-05 21.9 0.4 0.0002 20.9 0.3 1.5 1 0 0 1 1 1 1 F-box domain SHQ1 PF04925.10 EIE84220.1 - 1.1e-23 83.6 0.1 1.9e-23 82.8 0.1 1.4 1 0 0 1 1 1 1 SHQ1 protein CS PF04969.11 EIE84220.1 - 0.065 13.7 0.0 0.13 12.8 0.0 1.6 1 0 0 1 1 1 0 CS domain CLP_protease PF00574.18 EIE84220.1 - 0.069 12.8 0.1 0.84 9.2 0.0 2.4 3 0 0 3 3 3 0 Clp protease TmoB PF06234.7 EIE84222.1 - 0.026 14.3 0.0 0.05 13.4 0.0 1.4 1 0 0 1 1 1 0 Toluene-4-monooxygenase system protein B (TmoB) Med21 PF11221.3 EIE84223.1 - 1.1e-14 54.5 0.4 1.4e-14 54.2 0.3 1.1 1 0 0 1 1 1 1 Subunit 21 of Mediator complex Lipoprotein_7 PF01540.11 EIE84223.1 - 0.0034 16.5 0.1 0.0036 16.4 0.1 1.0 1 0 0 1 1 1 1 Adhesin lipoprotein Syntaxin_2 PF14523.1 EIE84223.1 - 0.013 15.5 0.2 0.014 15.3 0.1 1.2 1 0 0 1 1 1 0 Syntaxin-like protein Cas_APE2256 PF09651.5 EIE84223.1 - 0.029 14.1 0.5 1.7 8.3 0.0 2.2 1 1 1 2 2 2 0 CRISPR-associated protein (Cas_APE2256) Aa_trans PF01490.13 EIE84224.1 - 5e-28 97.7 20.5 1.4e-27 96.2 14.2 1.6 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein SPC25 PF06703.6 EIE84224.1 - 0.018 14.6 0.2 0.04 13.5 0.2 1.6 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Orbi_NS3 PF01616.11 EIE84224.1 - 1.8 7.5 5.1 0.56 9.1 0.6 2.1 2 0 0 2 2 2 0 Orbivirus NS3 DUF373 PF04123.8 EIE84224.1 - 5.5 5.8 11.5 0.29 10.1 4.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF373) Pex24p PF06398.6 EIE84224.1 - 9.9 4.8 9.7 16 4.1 6.7 1.5 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin Metallophos PF00149.23 EIE84226.1 - 2.9e-45 154.1 0.2 3.5e-45 153.8 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase F-box-like PF12937.2 EIE84227.1 - 3.9e-11 42.4 0.8 1.3e-10 40.8 0.5 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIE84227.1 - 5.1e-05 22.8 0.6 0.00042 19.8 0.4 2.7 1 1 0 1 1 1 1 F-box domain Ribosomal_L29e PF01779.12 EIE84228.1 - 2.3e-22 78.5 14.1 3.3e-22 78.0 9.8 1.3 1 0 0 1 1 1 1 Ribosomal L29e protein family HMGL-like PF00682.14 EIE84230.1 - 1.9e-71 240.4 0.1 3.4e-71 239.6 0.0 1.4 1 0 0 1 1 1 1 HMGL-like UvrD_C PF13361.1 EIE84230.1 - 0.00054 19.5 0.1 0.4 10.0 0.0 2.3 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain Bac_surface_Ag PF01103.18 EIE84231.1 - 6e-22 78.5 0.0 7.2e-22 78.2 0.0 1.1 1 0 0 1 1 1 1 Surface antigen HLH PF00010.21 EIE84232.1 - 6.8e-11 41.6 1.7 3.1e-10 39.5 0.9 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain MRP-L28 PF09812.4 EIE84232.1 - 0.093 12.5 0.3 0.15 11.9 0.2 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 DUF1917 PF08939.5 EIE84233.1 - 0.0097 15.6 1.4 0.012 15.4 1.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1917) Vfa1 PF08432.5 EIE84233.1 - 0.14 12.1 12.5 0.16 11.9 8.7 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CDC45 PF02724.9 EIE84233.1 - 0.23 9.4 5.4 0.23 9.4 3.8 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF4557 PF15101.1 EIE84233.1 - 0.31 10.8 2.2 0.36 10.6 1.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DUF262 PF03235.9 EIE84233.1 - 0.38 10.6 3.8 0.42 10.5 2.6 1.0 1 0 0 1 1 1 0 Protein of unknown function DUF262 Selenoprotein_S PF06936.6 EIE84233.1 - 0.4 10.1 9.7 0.46 10.0 6.7 1.1 1 0 0 1 1 1 0 Selenoprotein S (SelS) BTV_NS2 PF04514.7 EIE84233.1 - 0.46 9.3 10.9 0.52 9.1 7.6 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 U79_P34 PF03064.11 EIE84233.1 - 0.57 9.6 10.1 0.6 9.5 7.0 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF1510 PF07423.6 EIE84233.1 - 0.65 9.3 10.1 0.72 9.1 7.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) RR_TM4-6 PF06459.7 EIE84233.1 - 0.69 9.7 9.0 0.76 9.6 6.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Paf1 PF03985.8 EIE84233.1 - 0.69 8.5 10.2 0.79 8.3 7.1 1.0 1 0 0 1 1 1 0 Paf1 RNase_H2-Ydr279 PF09468.5 EIE84233.1 - 0.7 9.0 7.8 0.79 8.8 5.4 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) DUF2413 PF10310.4 EIE84233.1 - 0.81 8.4 8.5 0.96 8.1 5.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) NARP1 PF12569.3 EIE84233.1 - 0.9 8.2 12.4 1 8.0 8.6 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DDHD PF02862.12 EIE84233.1 - 0.92 9.2 4.3 1 9.0 3.0 1.1 1 0 0 1 1 1 0 DDHD domain Pox_Ag35 PF03286.9 EIE84233.1 - 1.6 8.2 10.6 1.9 7.9 7.4 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein HlyD PF00529.15 EIE84233.1 - 2.3 7.4 6.8 2.6 7.2 4.7 1.1 1 0 0 1 1 1 0 HlyD family secretion protein RNA_pol_Rpc4 PF05132.9 EIE84233.1 - 3.7 7.5 7.5 5 7.1 5.2 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 Ycf1 PF05758.7 EIE84233.1 - 8.1 4.0 8.7 8.5 3.9 6.0 1.0 1 0 0 1 1 1 0 Ycf1 YqfQ PF14181.1 EIE84233.1 - 8.8 6.3 9.5 11 5.9 6.6 1.2 1 0 0 1 1 1 0 YqfQ-like protein Pkinase PF00069.20 EIE84236.1 - 9.9e-52 175.6 0.0 9.2e-50 169.2 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE84236.1 - 2.7e-28 98.7 0.0 4.1e-28 98.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE84236.1 - 3.6e-06 26.1 0.1 1.3e-05 24.3 0.0 1.7 1 1 0 2 2 2 1 Kinase-like APH PF01636.18 EIE84236.1 - 0.048 13.3 0.0 0.6 9.7 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 EIE84236.1 - 0.14 11.2 0.2 0.5 9.3 0.1 1.8 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Arginase PF00491.16 EIE84238.1 - 7.7e-88 294.3 0.0 9.6e-88 294.0 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 EIE84238.1 - 0.0019 18.4 0.2 0.0045 17.2 0.1 1.6 1 0 0 1 1 1 1 UPF0489 domain Bromodomain PF00439.20 EIE84240.1 - 1.9e-41 139.8 3.0 8.4e-20 70.4 0.3 2.5 2 0 0 2 2 2 2 Bromodomain Band_7 PF01145.20 EIE84241.1 - 4.7e-23 81.9 3.4 6.9e-23 81.4 2.3 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family E_Pc_C PF06752.7 EIE84241.1 - 0.012 15.1 0.1 0.26 10.7 0.0 2.0 2 0 0 2 2 2 0 Enhancer of Polycomb C-terminus Mu-like_Com PF10122.4 EIE84242.1 - 0.05 12.6 0.7 0.05 12.6 0.5 2.9 3 0 0 3 3 3 0 Mu-like prophage protein Com Uds1 PF15456.1 EIE84243.1 - 4.8e-06 26.5 3.2 4.1e-05 23.5 0.1 2.2 2 0 0 2 2 2 2 Up-regulated During Septation Mhr1 PF12829.2 EIE84245.1 - 2.1e-07 30.6 0.4 0.008 15.9 0.0 2.3 1 1 1 2 2 2 2 Transcriptional regulation of mitochondrial recombination LigB PF02900.13 EIE84246.1 - 1.4e-18 66.8 0.0 2.9e-17 62.5 0.0 2.0 1 1 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Lysine_decarbox PF03641.9 EIE84247.1 - 1.8e-39 134.6 0.0 2.2e-39 134.3 0.0 1.1 1 0 0 1 1 1 1 Possible lysine decarboxylase Aph-1 PF06105.7 EIE84250.1 - 2e-22 79.6 20.9 5.8e-17 61.7 6.1 2.8 1 1 2 3 3 3 3 Aph-1 protein DctQ PF04290.7 EIE84250.1 - 2.2 8.0 7.7 12 5.7 5.3 2.2 1 1 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component Cyd_oper_YbgE PF09600.5 EIE84251.1 - 0.066 13.3 4.2 0.19 11.8 0.7 2.2 2 1 0 2 2 2 0 Cyd operon protein YbgE (Cyd_oper_YbgE) Methyltransf_23 PF13489.1 EIE84254.1 - 1.8e-06 27.8 0.0 5.8e-06 26.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIE84254.1 - 0.027 14.9 0.0 0.087 13.3 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Tox-REase-7 PF15649.1 EIE84254.1 - 0.074 13.1 1.0 0.16 12.1 0.7 1.6 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 7 IMPDH PF00478.20 EIE84255.1 - 1.3e-138 461.7 4.4 1.5e-138 461.5 3.1 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 EIE84255.1 - 5.1e-13 48.5 0.0 5e-06 26.1 0.0 2.4 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.13 EIE84255.1 - 2e-10 40.0 0.9 1.3e-09 37.4 0.6 2.1 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.10 EIE84255.1 - 9.1e-09 34.9 1.3 7.7e-06 25.2 0.6 2.3 2 0 0 2 2 2 2 Nitronate monooxygenase His_biosynth PF00977.16 EIE84255.1 - 2.9e-05 23.4 4.2 0.0014 17.9 0.3 2.8 2 1 1 3 3 3 2 Histidine biosynthesis protein ThiG PF05690.9 EIE84255.1 - 0.00041 19.4 1.4 0.0016 17.6 0.2 2.3 1 1 1 2 2 2 1 Thiazole biosynthesis protein ThiG PK PF00224.16 EIE84255.1 - 0.024 13.2 0.0 0.055 12.0 0.0 1.6 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain Aldolase PF01081.14 EIE84255.1 - 0.036 13.2 0.9 0.077 12.1 0.0 2.0 2 0 0 2 2 2 0 KDPG and KHG aldolase Cpn60_TCP1 PF00118.19 EIE84256.1 - 5.3e-145 483.7 2.4 6.1e-145 483.5 1.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CPT PF07931.7 EIE84256.1 - 0.042 13.4 0.1 0.33 10.5 0.1 2.2 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein DUF4241 PF14025.1 EIE84256.1 - 0.14 11.8 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4241) rve PF00665.21 EIE84257.1 - 1.2e-18 67.3 0.0 1.8e-18 66.7 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain CBM_4_9 PF02018.12 EIE84257.1 - 0.096 12.6 0.0 0.22 11.5 0.0 1.7 1 1 0 1 1 1 0 Carbohydrate binding domain RVT_1 PF00078.22 EIE84258.1 - 4.3e-10 39.2 0.2 1.1e-09 38.0 0.1 1.6 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2790 PF10976.3 EIE84259.1 - 0.019 14.7 0.1 0.027 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2790) DUF2271 PF10029.4 EIE84259.1 - 0.13 11.7 0.4 0.21 11.0 0.3 1.5 1 1 0 1 1 1 0 Predicted periplasmic protein (DUF2271) DUF3085 PF11284.3 EIE84261.1 - 0.11 12.7 0.0 0.29 11.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3085) Mito_carr PF00153.22 EIE84262.1 - 1.1e-52 175.7 0.2 1.1e-24 85.8 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.27 EIE84262.1 - 1.9e-13 48.6 2.8 0.00021 20.3 0.0 4.9 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.1 EIE84262.1 - 9.1e-13 46.9 3.2 0.00056 19.5 0.0 5.3 5 0 0 5 5 5 2 EF-hand domain EF-hand_7 PF13499.1 EIE84262.1 - 4.1e-10 39.6 7.1 0.00089 19.3 0.2 4.7 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_8 PF13833.1 EIE84262.1 - 3.9e-08 32.7 0.9 0.19 11.4 0.0 3.7 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 EIE84262.1 - 0.0014 17.8 1.3 0.74 9.2 0.1 3.0 2 0 0 2 2 2 2 EF hand DUF4451 PF14616.1 EIE84264.1 - 0.012 15.3 2.6 0.016 14.9 1.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4451) zinc_ribbon_4 PF13717.1 EIE84264.1 - 0.019 14.6 0.4 0.029 14.0 0.3 1.3 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EIE84264.1 - 0.02 14.4 0.4 0.03 13.9 0.3 1.3 1 0 0 1 1 1 0 zinc-ribbon domain CoiA PF06054.6 EIE84264.1 - 0.024 13.5 0.3 0.028 13.3 0.2 1.2 1 0 0 1 1 1 0 Competence protein CoiA-like family Zn-ribbon_8 PF09723.5 EIE84264.1 - 0.051 13.5 0.9 0.11 12.4 0.6 1.5 1 0 0 1 1 1 0 Zinc ribbon domain C1_4 PF07975.7 EIE84264.1 - 0.063 13.2 0.9 0.13 12.3 0.6 1.4 1 0 0 1 1 1 0 TFIIH C1-like domain zf-C2H2 PF00096.21 EIE84264.1 - 0.085 13.2 1.7 0.085 13.2 1.2 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIE84264.1 - 0.1 12.9 2.5 0.1 12.9 1.8 2.8 3 0 0 3 3 3 0 Zinc-finger double domain Zn_ribbon_recom PF13408.1 EIE84264.1 - 0.31 11.3 4.3 0.62 10.3 3.0 1.6 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain zf-C2H2_4 PF13894.1 EIE84264.1 - 8.9 6.9 12.5 44 4.7 8.0 2.4 1 1 0 1 1 1 0 C2H2-type zinc finger UPF0079 PF02367.12 EIE84266.1 - 0.02 14.5 0.0 0.02 14.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 ResIII PF04851.10 EIE84266.1 - 0.098 12.4 0.0 0.098 12.4 0.0 1.1 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit CENP-B_dimeris PF09026.5 EIE84268.1 - 0.45 10.7 4.6 0.93 9.7 3.2 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Arrestin_N PF00339.24 EIE84269.1 - 2.6e-11 43.5 0.0 1.8e-08 34.3 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EIE84269.1 - 1.6e-06 28.2 0.3 3.4e-06 27.2 0.1 1.6 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Rgp1 PF08737.5 EIE84269.1 - 3e-05 23.3 4.9 0.0002 20.5 0.1 3.1 3 1 1 4 4 4 2 Rgp1 UDP-g_GGTase PF06427.6 EIE84269.1 - 0.022 14.0 0.1 0.04 13.2 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose:Glycoprotein Glucosyltransferase SNF2_N PF00176.18 EIE84272.1 - 6e-64 215.7 0.0 6e-64 215.7 0.0 2.6 2 1 0 2 2 2 1 SNF2 family N-terminal domain Chromo PF00385.19 EIE84272.1 - 4.4e-16 58.2 4.1 1.2e-07 31.3 0.1 3.4 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 EIE84272.1 - 4.2e-14 52.1 0.0 1.5e-13 50.4 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Mito_carr PF00153.22 EIE84273.1 - 1.7e-64 213.5 1.6 2.6e-21 75.1 0.3 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Sec8_exocyst PF04048.9 EIE84274.1 - 0.0014 18.2 6.5 0.0016 18.0 4.1 1.4 1 1 0 1 1 1 1 Sec8 exocyst complex component specific domain V-SNARE_C PF12352.3 EIE84274.1 - 0.0016 18.4 0.8 0.0041 17.1 0.6 1.6 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus DUF3340 PF11818.3 EIE84274.1 - 0.0039 17.1 5.9 0.0062 16.5 4.0 1.3 1 1 0 1 1 1 1 C-terminal domain of tail specific protease (DUF3340) STAT_alpha PF01017.15 EIE84274.1 - 0.015 15.0 1.9 0.015 15.0 1.3 2.0 1 1 1 2 2 2 0 STAT protein, all-alpha domain DASH_Duo1 PF08651.5 EIE84274.1 - 0.015 14.8 2.2 0.028 13.9 0.2 2.4 3 1 0 3 3 3 0 DASH complex subunit Duo1 DUF948 PF06103.6 EIE84274.1 - 0.072 12.9 5.3 0.68 9.8 1.1 2.7 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) WXG100 PF06013.7 EIE84274.1 - 0.074 13.0 1.5 0.19 11.7 1.0 1.7 1 1 0 1 1 1 0 Proteins of 100 residues with WXG RHH_2 PF03693.9 EIE84274.1 - 0.077 13.1 1.3 0.15 12.2 0.1 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0156) IncA PF04156.9 EIE84274.1 - 0.08 12.5 10.2 0.11 12.0 7.0 1.2 1 0 0 1 1 1 0 IncA protein GAS PF13851.1 EIE84274.1 - 0.09 11.9 9.0 0.14 11.3 6.2 1.3 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding APG6 PF04111.7 EIE84274.1 - 0.092 11.7 8.1 0.12 11.3 5.6 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Sec5 PF15469.1 EIE84274.1 - 0.13 12.0 5.5 0.21 11.3 3.7 1.5 1 1 0 1 1 1 0 Exocyst complex component Sec5 LTXXQ PF07813.7 EIE84274.1 - 0.21 12.0 6.4 0.48 10.9 4.4 1.6 1 1 0 1 1 1 0 LTXXQ motif family protein ATP-synt_DE PF00401.15 EIE84274.1 - 1.5 8.7 5.2 1.3 8.9 0.4 2.5 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain CDC37_N PF03234.9 EIE84274.1 - 1.8 8.8 6.6 2.5 8.4 4.6 1.2 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding Syntaxin PF00804.20 EIE84274.1 - 3 8.0 9.6 2.2 8.4 0.6 2.2 1 1 1 2 2 2 0 Syntaxin DUF4164 PF13747.1 EIE84274.1 - 3.1 7.9 8.1 1.1 9.4 1.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Nsp1_C PF05064.8 EIE84274.1 - 6.4 6.4 10.6 1.9 8.1 2.4 2.2 1 1 1 2 2 2 0 Nsp1-like C-terminal region COG4 PF08318.7 EIE84275.1 - 1.8e-33 115.6 2.7 2.5e-33 115.2 1.9 1.2 1 0 0 1 1 1 1 COG4 transport protein RINT1_TIP1 PF04437.8 EIE84275.1 - 6e-05 21.7 3.8 0.00039 19.1 2.6 2.0 1 1 0 1 1 1 1 RINT-1 / TIP-1 family EI24 PF07264.6 EIE84277.1 - 4.1e-07 29.6 5.7 5e-07 29.3 4.0 1.1 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Tetraspannin PF00335.15 EIE84278.1 - 9.8e-06 25.0 0.8 1e-05 24.9 0.6 1.1 1 0 0 1 1 1 1 Tetraspanin family MitoNEET_N PF10660.4 EIE84278.1 - 0.089 12.6 1.3 1.4 8.8 0.0 2.5 2 0 0 2 2 2 0 Iron-containing outer mitochondrial membrane protein N-terminus TPR_1 PF00515.23 EIE84279.1 - 6.3e-47 155.3 40.2 2.8e-08 33.0 0.0 11.1 10 2 1 11 11 11 9 Tetratricopeptide repeat TPR_11 PF13414.1 EIE84279.1 - 1.4e-43 146.3 29.5 4.7e-12 45.3 0.3 6.7 2 1 5 7 7 7 7 TPR repeat TPR_2 PF07719.12 EIE84279.1 - 1.3e-41 137.1 37.4 1e-05 25.0 0.0 10.5 10 1 0 10 10 9 8 Tetratricopeptide repeat TPR_12 PF13424.1 EIE84279.1 - 5.6e-32 109.5 28.9 9.3e-08 31.9 0.6 5.8 2 2 4 6 6 6 6 Tetratricopeptide repeat TPR_17 PF13431.1 EIE84279.1 - 1.8e-31 105.6 26.8 0.00022 21.1 0.1 9.8 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_16 PF13432.1 EIE84279.1 - 6.5e-28 96.7 22.1 1.3e-08 35.3 0.1 7.0 4 1 4 8 8 7 7 Tetratricopeptide repeat TPR_8 PF13181.1 EIE84279.1 - 3.1e-26 89.1 38.0 1.8e-05 24.1 2.1 9.5 7 2 2 9 9 9 7 Tetratricopeptide repeat TPR_19 PF14559.1 EIE84279.1 - 2.1e-24 85.6 19.5 8.4e-06 26.0 0.4 7.2 3 2 2 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.1 EIE84279.1 - 5.5e-24 82.4 16.4 0.0017 18.7 0.0 8.7 2 2 6 8 8 8 7 Tetratricopeptide repeat TPR_7 PF13176.1 EIE84279.1 - 9.4e-19 65.6 24.4 0.0032 17.1 0.4 9.6 8 2 0 8 8 8 5 Tetratricopeptide repeat TPR_6 PF13174.1 EIE84279.1 - 2.4e-15 55.8 33.0 0.032 14.6 0.3 9.4 9 1 0 9 9 9 4 Tetratricopeptide repeat TPR_9 PF13371.1 EIE84279.1 - 1.3e-12 47.3 16.1 0.00092 19.0 0.4 6.3 2 2 5 7 7 7 4 Tetratricopeptide repeat Apc3 PF12895.2 EIE84279.1 - 1.5e-09 37.8 24.8 7.8e-05 22.7 5.8 4.5 2 1 3 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 EIE84279.1 - 2e-08 33.6 16.4 0.00047 19.3 1.1 4.4 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_20 PF14561.1 EIE84279.1 - 0.00088 19.3 8.7 0.82 9.8 0.0 6.0 5 2 2 7 7 5 1 Tetratricopeptide repeat TPR_10 PF13374.1 EIE84279.1 - 0.0064 16.3 27.2 0.03 14.2 0.1 7.2 7 0 0 7 7 7 1 Tetratricopeptide repeat ChAPs PF09295.5 EIE84279.1 - 0.042 12.6 5.4 0.53 8.9 0.2 2.9 2 1 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_3 PF07720.7 EIE84279.1 - 0.19 11.5 15.2 7.2 6.5 0.5 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat MIT PF04212.13 EIE84279.1 - 0.77 9.6 27.6 2.1 8.2 0.2 6.5 7 0 0 7 7 7 0 MIT (microtubule interacting and transport) domain TPR_21 PF09976.4 EIE84279.1 - 1.2 9.0 20.9 1 9.3 0.9 4.9 4 2 1 5 5 5 0 Tetratricopeptide repeat DDHD PF02862.12 EIE84279.1 - 3.6 7.3 13.6 1.3 8.7 7.2 1.8 2 0 0 2 2 2 0 DDHD domain RNA_pol_Rpb6 PF01192.17 EIE84280.1 - 2.6e-18 65.4 0.4 3.9e-18 64.9 0.3 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 Gln-synt_C PF00120.19 EIE84281.1 - 5.3e-24 84.7 0.1 5.8e-24 84.6 0.0 1.0 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Peptidase_M24 PF00557.19 EIE84282.1 - 1.4e-57 194.6 0.1 1.8e-57 194.2 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EIE84282.1 - 9.1e-24 83.3 0.0 2.1e-23 82.1 0.0 1.6 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain DUF4451 PF14616.1 EIE84283.1 - 1.4e-24 86.2 1.5 3e-24 85.1 1.1 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4451) Prp19_bind PF06991.6 EIE84283.1 - 1.4 8.0 9.3 0.027 13.7 1.1 1.9 2 1 0 2 2 2 0 Splicing factor, Prp19-binding domain DUF4611 PF15387.1 EIE84283.1 - 9.1 6.5 9.8 0.62 10.2 2.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) CENP-B_dimeris PF09026.5 EIE84283.1 - 9.6 6.5 13.2 0.28 11.4 3.8 2.1 2 0 0 2 2 2 0 Centromere protein B dimerisation domain LysM PF01476.15 EIE84284.1 - 4.9e-05 23.1 0.0 0.00025 20.8 0.0 2.1 2 0 0 2 2 2 1 LysM domain 3D PF06725.6 EIE84284.1 - 0.049 13.6 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 3D domain PDEase_I PF00233.14 EIE84286.1 - 5.8e-51 173.5 1.1 1.3e-50 172.4 0.7 1.6 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.17 EIE84286.1 - 0.0019 18.2 0.1 0.0041 17.1 0.1 1.6 1 0 0 1 1 1 1 HD domain FHA PF00498.21 EIE84287.1 - 3.4e-16 59.1 0.4 5.8e-16 58.3 0.2 1.4 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 EIE84287.1 - 1.3e-07 31.3 16.1 2.1e-07 30.6 11.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EIE84287.1 - 6.2e-05 23.0 9.3 0.00019 21.5 6.5 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EIE84287.1 - 6.2e-05 22.5 10.6 0.00011 21.8 7.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIE84287.1 - 0.00038 20.4 13.5 0.00067 19.6 9.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIE84287.1 - 0.005 16.5 14.0 0.0091 15.7 9.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Sec_GG PF07549.9 EIE84287.1 - 0.17 11.1 0.0 0.38 10.0 0.0 1.5 1 0 0 1 1 1 0 SecD/SecF GG Motif zf-Apc11 PF12861.2 EIE84287.1 - 0.22 11.4 6.8 0.41 10.5 4.7 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger SH2 PF00017.19 EIE84287.1 - 0.3 10.9 1.2 2.3 8.0 0.2 2.3 1 1 1 2 2 2 0 SH2 domain PHD PF00628.24 EIE84287.1 - 0.8 9.4 10.3 1.4 8.7 7.1 1.4 1 0 0 1 1 1 0 PHD-finger Suc_Fer-like PF06999.7 EIE84288.1 - 3.9e-41 141.5 0.3 1.1e-40 140.0 0.2 1.8 1 1 0 1 1 1 1 Sucrase/ferredoxin-like YukC PF10140.4 EIE84288.1 - 0.14 10.6 0.1 0.21 10.1 0.0 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Bromodomain PF00439.20 EIE84289.1 - 2.7e-50 168.2 0.6 7.7e-24 83.4 0.1 2.6 2 0 0 2 2 2 2 Bromodomain FlxA PF14282.1 EIE84289.1 - 0.0014 18.5 10.6 0.0014 18.5 7.3 3.5 3 1 0 3 3 3 1 FlxA-like protein DUF4254 PF14063.1 EIE84289.1 - 0.014 15.0 0.8 0.27 10.8 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4254) DUF3573 PF12097.3 EIE84289.1 - 0.46 9.0 2.2 0.82 8.2 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) MerR-DNA-bind PF09278.6 EIE84289.1 - 4.4 7.7 5.6 2.5 8.5 0.9 2.6 3 0 0 3 3 3 0 MerR, DNA binding DPBB_1 PF03330.13 EIE84290.1 - 2.4e-05 24.2 0.5 4.9e-05 23.2 0.3 1.6 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EIE84290.1 - 0.00019 21.0 0.5 0.00029 20.4 0.4 1.3 1 1 0 1 1 1 1 Barwin family Integrase_Zn PF02022.14 EIE84290.1 - 0.088 12.2 0.4 0.18 11.2 0.3 1.5 1 0 0 1 1 1 0 Integrase Zinc binding domain Lactamase_B_4 PF13691.1 EIE84292.1 - 0.031 13.7 0.4 0.087 12.3 0.0 2.0 3 0 0 3 3 3 0 tRNase Z endonuclease KxDL PF10241.4 EIE84292.1 - 0.41 10.5 10.5 0.055 13.3 3.7 2.2 2 1 0 2 2 2 0 Uncharacterized conserved protein DDE_Tnp_1_3 PF13612.1 EIE84292.1 - 0.77 9.4 10.5 0.24 11.1 1.6 2.5 2 0 0 2 2 2 0 Transposase DDE domain TruB_N PF01509.13 EIE84293.1 - 7.1e-42 143.0 0.0 9.4e-42 142.6 0.0 1.1 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) UVR PF02151.14 EIE84294.1 - 0.00019 20.8 0.8 0.00019 20.8 0.6 5.4 6 2 0 6 6 6 1 UvrB/uvrC motif HA2 PF04408.18 EIE84295.1 - 4.5e-22 78.0 0.0 4.5e-22 78.0 0.0 3.4 4 1 0 4 4 4 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EIE84295.1 - 2.1e-13 49.9 0.1 7.2e-13 48.2 0.1 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EIE84295.1 - 3.6e-09 36.3 2.4 3.8e-09 36.2 0.1 2.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EIE84295.1 - 2.5e-06 27.6 0.1 1.4e-05 25.2 0.1 2.3 1 0 0 1 1 1 1 AAA domain OB_NTP_bind PF07717.11 EIE84295.1 - 2.6e-06 27.2 0.0 9.1e-06 25.4 0.0 2.0 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold KaiC PF06745.8 EIE84295.1 - 0.0062 15.6 0.0 0.0062 15.6 0.0 2.4 3 0 0 3 3 3 1 KaiC ABC_tran PF00005.22 EIE84295.1 - 0.41 10.9 0.0 0.41 10.9 0.0 3.9 4 1 0 4 4 4 0 ABC transporter Aa_trans PF01490.13 EIE84296.1 - 1.7e-43 148.6 18.9 1.9e-43 148.5 13.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2516 PF10724.4 EIE84296.1 - 5.8 6.9 11.8 22 5.1 1.7 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2516) DPBB_1 PF03330.13 EIE84297.1 - 2.4e-05 24.2 0.5 4.9e-05 23.2 0.3 1.6 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EIE84297.1 - 0.00019 21.0 0.5 0.00029 20.4 0.4 1.3 1 1 0 1 1 1 1 Barwin family Integrase_Zn PF02022.14 EIE84297.1 - 0.088 12.2 0.4 0.18 11.2 0.3 1.5 1 0 0 1 1 1 0 Integrase Zinc binding domain Fungal_trans PF04082.13 EIE84298.1 - 5.8e-42 143.3 0.3 1.8e-41 141.7 0.0 1.9 2 1 1 3 3 3 1 Fungal specific transcription factor domain Met_10 PF02475.11 EIE84299.1 - 6.2e-58 195.6 0.2 8.2e-58 195.3 0.1 1.1 1 0 0 1 1 1 1 Met-10+ like-protein TRM PF02005.11 EIE84299.1 - 8.4e-05 21.6 0.1 9.4e-05 21.4 0.0 1.3 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_18 PF12847.2 EIE84299.1 - 0.00091 19.7 0.0 0.0014 19.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EIE84299.1 - 0.0015 17.6 0.0 0.0023 17.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 EIE84299.1 - 0.034 14.1 0.0 0.052 13.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain EHN PF06441.7 EIE84299.1 - 0.054 13.4 0.4 2.3 8.1 0.1 2.8 1 1 1 2 2 2 0 Epoxide hydrolase N terminus Presenilin PF01080.12 EIE84300.1 - 1.4e-52 178.9 0.0 2.2e-52 178.2 0.0 1.2 1 0 0 1 1 1 1 Presenilin DUF1119 PF06550.6 EIE84300.1 - 4.9e-05 22.6 0.3 0.00032 19.9 0.1 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF1119) Peptidase_A22B PF04258.8 EIE84300.1 - 9.1e-05 22.0 1.5 0.00023 20.7 0.9 1.7 2 0 0 2 2 2 1 Signal peptide peptidase Nucleoplasmin PF03066.10 EIE84300.1 - 0.04 13.4 1.8 0.058 12.9 1.2 1.3 1 0 0 1 1 1 0 Nucleoplasmin Sigma70_ner PF04546.8 EIE84300.1 - 0.25 10.9 2.2 0.33 10.5 1.6 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region PI3_PI4_kinase PF00454.22 EIE84301.1 - 3.1e-22 79.1 0.1 1.2e-21 77.2 0.0 2.0 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 EIE84301.1 - 1e-21 76.9 0.1 4.7e-21 74.8 0.0 2.2 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) CCER1 PF15482.1 EIE84301.1 - 0.13 11.8 0.1 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing glutamate-rich protein family 1 Ribosomal_S5 PF00333.15 EIE84302.1 - 5.3e-28 96.5 1.6 5.3e-28 96.5 1.1 1.8 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 EIE84302.1 - 2.5e-22 77.9 0.0 4.2e-22 77.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain HMG_box PF00505.14 EIE84303.1 - 2.1e-18 66.3 4.7 2.1e-18 66.3 3.3 2.0 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EIE84303.1 - 2.8e-14 53.2 3.9 8.7e-14 51.6 2.7 1.9 1 0 0 1 1 1 1 HMG-box domain Nucleoplasmin PF03066.10 EIE84304.1 - 0.0018 17.7 7.2 0.0018 17.7 5.0 2.0 2 0 0 2 2 2 1 Nucleoplasmin TRAP_alpha PF03896.11 EIE84304.1 - 0.0094 14.9 2.2 0.019 13.9 1.5 1.5 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit LEF-8 PF04941.7 EIE84304.1 - 0.17 9.5 0.1 0.24 9.0 0.1 1.1 1 0 0 1 1 1 0 Late expression factor 8 (LEF-8) BSP_II PF05432.6 EIE84304.1 - 0.18 11.0 21.1 0.037 13.3 11.7 1.8 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) CENP-B_dimeris PF09026.5 EIE84304.1 - 0.6 10.3 16.8 0.58 10.4 9.1 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Ycf1 PF05758.7 EIE84304.1 - 0.84 7.2 5.1 0.29 8.8 0.6 1.9 2 0 0 2 2 2 0 Ycf1 Nop14 PF04147.7 EIE84304.1 - 1 7.2 12.4 2 6.2 8.6 1.4 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 EIE84304.1 - 1.4 6.8 5.8 2.2 6.2 4.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Ribosomal_60s PF00428.14 EIE84304.1 - 1.5 9.2 21.5 0.22 11.9 11.1 2.5 2 1 0 2 2 2 0 60s Acidic ribosomal protein Paf1 PF03985.8 EIE84304.1 - 1.7 7.2 15.3 3.5 6.2 10.6 1.4 1 0 0 1 1 1 0 Paf1 OAD_gamma PF04277.8 EIE84304.1 - 2.4 8.5 4.5 42 4.6 1.4 2.5 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain VID27 PF08553.5 EIE84304.1 - 2.6 6.1 10.8 4.2 5.4 7.5 1.2 1 0 0 1 1 1 0 VID27 cytoplasmic protein FAM176 PF14851.1 EIE84304.1 - 3.7 7.2 9.3 10 5.7 4.2 2.4 2 0 0 2 2 2 0 FAM176 family CobT PF06213.7 EIE84304.1 - 6.3 5.8 14.2 14 4.7 9.9 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Sigma70_ner PF04546.8 EIE84304.1 - 8.4 5.9 14.5 0.17 11.5 4.5 2.1 3 0 0 3 3 3 0 Sigma-70, non-essential region Voldacs PF03517.8 EIE84304.1 - 9.7 6.0 11.8 6.7 6.5 5.5 2.1 2 0 0 2 2 2 0 Regulator of volume decrease after cellular swelling TFIID-31kDa PF02291.10 EIE84305.1 - 8.9e-51 171.0 0.0 1.2e-50 170.6 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.8 EIE84305.1 - 2.7e-06 27.0 0.0 4.5e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.19 EIE84305.1 - 1.1e-05 25.4 0.0 1.6e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EIE84305.1 - 0.00028 20.9 0.1 0.00049 20.2 0.1 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S TFIID_30kDa PF03540.8 EIE84305.1 - 0.00039 20.1 0.0 0.00092 18.9 0.0 1.7 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Ribonuclease_T2 PF00445.13 EIE84306.1 - 2.5e-21 76.1 0.0 3e-21 75.9 0.0 1.0 1 0 0 1 1 1 1 Ribonuclease T2 family DUF2170 PF09938.4 EIE84306.1 - 0.022 14.1 0.0 0.47 9.7 0.0 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2170) Aa_trans PF01490.13 EIE84307.1 - 1.6e-38 132.2 17.4 1.8e-38 132.0 12.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Virul_fac_BrkB PF03631.10 EIE84307.1 - 0.26 10.6 11.3 0.31 10.3 1.4 3.0 1 1 2 3 3 3 0 Virulence factor BrkB 7TMR-DISM_7TM PF07695.6 EIE84307.1 - 0.79 9.3 19.0 0.11 12.1 7.1 2.3 2 0 0 2 2 2 0 7TM diverse intracellular signalling PGM_PMM_I PF02878.11 EIE84308.1 - 1.3e-35 121.9 0.0 3e-35 120.7 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 EIE84308.1 - 2.9e-22 78.9 0.0 1.1e-21 77.1 0.0 2.0 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 EIE84308.1 - 8.6e-11 41.8 0.1 1.4e-10 41.1 0.1 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 EIE84308.1 - 1.8e-07 31.0 0.0 4.9e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain XPG_I PF00867.13 EIE84309.1 - 1.1e-26 92.6 0.1 8.2e-26 89.9 0.0 2.5 2 0 0 2 2 2 1 XPG I-region XPG_I_2 PF12813.2 EIE84309.1 - 0.0042 16.6 0.0 0.018 14.5 0.0 2.1 2 0 0 2 2 2 1 XPG domain containing Reo_sigmaC PF04582.7 EIE84311.1 - 0.21 10.7 8.4 0.87 8.6 0.4 2.6 1 1 2 3 3 3 0 Reovirus sigma C capsid protein Filament PF00038.16 EIE84311.1 - 0.44 9.9 41.2 0.36 10.2 6.0 2.6 1 1 1 2 2 2 0 Intermediate filament protein DUF4618 PF15397.1 EIE84311.1 - 0.53 9.5 43.9 0.067 12.5 23.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) NAS PF03059.11 EIE84311.1 - 0.56 9.3 6.6 0.12 11.5 0.8 2.1 1 1 0 2 2 2 0 Nicotianamine synthase protein Baculo_PEP_C PF04513.7 EIE84311.1 - 0.69 9.7 13.0 0.19 11.5 1.8 3.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus IZUMO PF15005.1 EIE84311.1 - 1.2 9.1 13.0 0.21 11.5 5.9 2.0 1 1 1 2 2 2 0 Izumo sperm-egg fusion Fungal_trans PF04082.13 EIE84312.1 - 4e-29 101.2 2.3 7.2e-28 97.1 0.0 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Ribosomal_L10 PF00466.15 EIE84313.1 - 9.2e-27 92.8 0.3 1.8e-26 91.9 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 EIE84313.1 - 1.2e-20 73.6 7.9 3.1e-20 72.3 3.7 2.3 2 0 0 2 2 2 1 60s Acidic ribosomal protein S19 PF06756.6 EIE84313.1 - 0.044 13.6 0.2 0.2 11.5 0.0 2.0 2 0 0 2 2 2 0 Chorion protein S19 C-terminal GTP1_OBG PF01018.17 EIE84314.1 - 3.5e-42 143.6 6.4 4.3e-27 94.6 3.2 2.2 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.18 EIE84314.1 - 5.4e-22 77.9 0.0 2.4e-21 75.8 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EIE84314.1 - 3.9e-11 42.4 0.1 9.1e-11 41.2 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.16 EIE84314.1 - 8.4e-07 28.3 0.0 1.5e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family ArgK PF03308.11 EIE84314.1 - 9.2e-05 21.3 0.4 0.24 10.1 0.1 2.2 2 0 0 2 2 2 2 ArgK protein MMR_HSR1_C PF08438.5 EIE84314.1 - 0.00012 22.2 0.4 0.00027 21.1 0.3 1.6 1 0 0 1 1 1 1 GTPase of unknown function C-terminal Gtr1_RagA PF04670.7 EIE84314.1 - 0.00097 18.3 0.0 0.0016 17.6 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EIE84314.1 - 0.0017 17.7 0.1 1.9 7.8 0.0 2.5 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain cobW PF02492.14 EIE84314.1 - 0.0095 15.3 0.0 0.54 9.6 0.0 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.22 EIE84314.1 - 0.012 15.9 0.0 0.029 14.6 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Dynamin_N PF00350.18 EIE84314.1 - 0.028 14.2 0.1 9 6.0 0.1 2.5 1 1 1 2 2 2 0 Dynamin family SRPRB PF09439.5 EIE84314.1 - 0.068 12.3 0.4 0.37 9.9 0.0 2.0 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Miro PF08477.8 EIE84314.1 - 0.075 13.5 0.0 0.25 11.8 0.0 2.0 1 1 0 1 1 1 0 Miro-like protein AAA_10 PF12846.2 EIE84314.1 - 0.093 12.1 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain Catalase PF00199.14 EIE84316.1 - 3.2e-156 519.8 0.3 4e-156 519.5 0.2 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EIE84316.1 - 3.1e-19 68.6 0.1 6.4e-19 67.5 0.1 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.19 EIE84316.1 - 0.0033 16.8 0.0 0.0077 15.6 0.0 1.6 1 0 0 1 1 1 1 DJ-1/PfpI family Catalase PF00199.14 EIE84317.1 - 6.4e-152 505.6 0.9 1e-151 505.0 0.6 1.3 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EIE84317.1 - 9.9e-22 76.5 0.3 1.9e-21 75.6 0.2 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.19 EIE84317.1 - 0.0012 18.2 0.0 0.0028 17.1 0.0 1.6 1 0 0 1 1 1 1 DJ-1/PfpI family DUF221 PF02714.10 EIE84318.1 - 8.7e-70 235.1 33.8 3.9e-37 127.8 3.1 3.0 2 1 1 3 3 3 2 Domain of unknown function DUF221 RSN1_TM PF13967.1 EIE84318.1 - 8e-28 96.9 4.0 8e-28 96.9 2.8 2.8 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EIE84318.1 - 3e-11 43.6 0.0 6.5e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) RA PF00788.18 EIE84319.1 - 6.4e-17 61.8 0.1 4.2e-08 33.5 0.1 3.0 2 0 0 2 2 2 2 Ras association (RalGDS/AF-6) domain SH3_1 PF00018.23 EIE84319.1 - 9.5e-06 24.9 0.0 2.4e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EIE84319.1 - 0.00055 19.4 0.0 0.0012 18.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EIE84319.1 - 0.089 12.2 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain DDE_3 PF13358.1 EIE84320.1 - 1.6e-27 96.0 0.0 3.3e-27 95.0 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.1 EIE84320.1 - 0.00022 21.9 0.4 0.00051 20.7 0.0 1.9 2 0 0 2 2 2 1 Homeodomain-like domain TPR_11 PF13414.1 EIE84321.1 - 5.3e-33 112.4 10.4 4.7e-16 58.1 0.1 5.5 3 2 2 5 5 5 5 TPR repeat TPR_1 PF00515.23 EIE84321.1 - 1.4e-22 78.2 2.9 2.2e-05 23.8 0.0 7.4 7 0 0 7 7 7 4 Tetratricopeptide repeat DnaJ PF00226.26 EIE84321.1 - 2.1e-22 78.6 3.8 2.1e-22 78.6 2.6 2.4 2 0 0 2 2 2 1 DnaJ domain TPR_2 PF07719.12 EIE84321.1 - 3.1e-20 70.3 3.6 0.0039 16.9 0.0 7.9 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.1 EIE84321.1 - 2.3e-19 69.5 0.1 6.8e-06 26.6 0.0 5.0 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 EIE84321.1 - 5.7e-16 58.6 7.1 0.00057 20.1 0.1 5.9 4 2 3 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 EIE84321.1 - 3.1e-14 52.2 0.2 0.19 12.4 0.0 7.2 4 3 4 8 8 7 4 Tetratricopeptide repeat TPR_9 PF13371.1 EIE84321.1 - 9.2e-14 51.0 5.1 2.9e-05 23.8 0.0 5.6 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 EIE84321.1 - 1.7e-13 49.6 5.1 0.0011 18.9 0.1 6.3 6 0 0 6 6 5 2 Tetratricopeptide repeat Ion_trans PF00520.26 EIE84321.1 - 2.7e-12 46.3 17.6 5.7e-12 45.3 12.2 1.6 1 0 0 1 1 1 1 Ion transport protein Apc3 PF12895.2 EIE84321.1 - 7.6e-10 38.7 14.7 0.00051 20.1 0.0 5.2 3 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 Ion_trans_2 PF07885.11 EIE84321.1 - 1.5e-09 37.4 11.5 1.5e-09 37.4 8.0 2.5 2 1 1 3 3 2 1 Ion channel TPR_8 PF13181.1 EIE84321.1 - 1.1e-07 31.0 9.5 0.02 14.6 0.1 7.5 7 1 1 8 8 8 1 Tetratricopeptide repeat TPR_6 PF13174.1 EIE84321.1 - 2.3e-05 24.5 1.5 2.5 8.7 0.0 6.0 6 0 0 6 6 5 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EIE84321.1 - 6.4e-05 22.7 3.4 2.8 7.8 0.2 5.0 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 EIE84321.1 - 0.00017 21.8 1.6 0.0013 19.0 0.0 3.0 3 1 0 3 3 3 1 Alkyl sulfatase dimerisation TPR_20 PF14561.1 EIE84321.1 - 0.0007 19.6 8.9 0.74 9.9 0.0 5.9 4 3 2 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.1 EIE84321.1 - 0.00087 19.1 11.9 0.092 12.6 0.4 5.2 4 2 2 6 6 6 3 Tetratricopeptide repeat DUF357 PF04010.8 EIE84321.1 - 0.016 14.8 3.1 0.74 9.5 0.0 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF357) SWIM PF04434.12 EIE84323.1 - 0.0042 16.5 0.6 0.0084 15.5 0.4 1.4 1 0 0 1 1 1 1 SWIM zinc finger Pepsin-I3 PF06394.8 EIE84323.1 - 0.044 13.4 0.1 0.066 12.8 0.1 1.3 1 0 0 1 1 1 0 Pepsin inhibitor-3-like repeated domain CAP_GLY PF01302.20 EIE84324.1 - 3.4e-27 93.9 0.7 5.5e-27 93.2 0.5 1.3 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 EIE84324.1 - 3.3e-26 91.3 0.0 7.7e-26 90.1 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.18 EIE84324.1 - 0.023 14.0 0.1 0.14 11.5 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin family RRM_1 PF00076.17 EIE84325.1 - 1.4e-11 43.8 0.1 2.6e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE84325.1 - 7.9e-11 41.7 0.0 1.5e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE84325.1 - 1.5e-10 40.7 0.0 4.2e-10 39.3 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EIE84325.1 - 0.039 13.7 0.1 0.039 13.7 0.0 1.8 2 0 0 2 2 2 0 RNA binding motif MIP-T3 PF10243.4 EIE84325.1 - 0.47 8.8 10.1 0.5 8.7 7.0 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 SPX PF03105.14 EIE84325.1 - 0.84 9.3 14.3 1.2 8.8 9.9 1.2 1 0 0 1 1 1 0 SPX domain NAP PF00956.13 EIE84326.1 - 3.1e-84 281.9 9.3 3.1e-84 281.9 6.4 1.9 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Cwf_Cwc_15 PF04889.7 EIE84326.1 - 3.7 7.2 18.4 2.3 7.8 6.5 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein ubiquitin PF00240.18 EIE84327.1 - 8.9e-23 79.4 3.5 1.6e-22 78.6 2.4 1.5 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 EIE84327.1 - 7.7e-21 73.3 5.0 4.9e-13 48.5 0.1 2.6 2 0 0 2 2 2 2 UBA/TS-N domain XPC-binding PF09280.6 EIE84327.1 - 3.1e-20 71.3 5.2 3.1e-20 71.3 3.6 2.0 2 0 0 2 2 2 1 XPC-binding domain Rad60-SLD PF11976.3 EIE84327.1 - 1.5e-10 40.5 5.5 1.5e-10 40.5 3.8 1.8 2 0 0 2 2 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EIE84327.1 - 0.012 15.7 1.3 0.026 14.6 0.1 2.1 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain S4 PF01479.20 EIE84327.1 - 0.016 14.5 0.0 0.042 13.2 0.0 1.6 1 0 0 1 1 1 0 S4 domain Ubiquitin_2 PF14560.1 EIE84327.1 - 0.018 15.2 0.4 0.057 13.6 0.2 1.8 1 0 0 1 1 1 0 Ubiquitin-like domain UBA_3 PF09288.5 EIE84327.1 - 0.02 14.4 0.0 6.4 6.4 0.0 2.5 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain Rad60-SLD_2 PF13881.1 EIE84327.1 - 0.022 14.6 0.3 0.022 14.6 0.2 2.2 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like DNA_pack_N PF02500.10 EIE84327.1 - 0.13 11.7 2.1 0.24 10.9 1.5 1.4 1 0 0 1 1 1 0 Probable DNA packing protein, N-terminus PAT1 PF09770.4 EIE84327.1 - 0.66 8.1 31.8 0.96 7.6 22.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Tim54 PF11711.3 EIE84327.1 - 4 5.9 14.1 0.066 11.8 1.8 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Oxidored_FMN PF00724.15 EIE84328.1 - 3.3e-74 249.9 0.0 4.1e-74 249.6 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.12 EIE84328.1 - 0.0049 15.7 0.1 0.008 15.0 0.1 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) UNC-93 PF05978.11 EIE84328.1 - 0.065 12.7 0.1 0.14 11.6 0.1 1.5 1 0 0 1 1 1 0 Ion channel regulatory protein UNC-93 Oxidored_FMN PF00724.15 EIE84329.1 - 3.3e-74 249.9 0.0 4.1e-74 249.6 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.12 EIE84329.1 - 0.0049 15.7 0.1 0.008 15.0 0.1 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) UNC-93 PF05978.11 EIE84329.1 - 0.065 12.7 0.1 0.14 11.6 0.1 1.5 1 0 0 1 1 1 0 Ion channel regulatory protein UNC-93 zf-CCHC PF00098.18 EIE84331.1 - 0.072 13.0 1.4 0.072 13.0 1.0 3.3 3 0 0 3 3 3 0 Zinc knuckle RVT_1 PF00078.22 EIE84332.1 - 5.5e-22 78.1 0.2 1.1e-21 77.1 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Vsr PF03852.10 EIE84333.1 - 0.035 13.7 0.0 0.076 12.6 0.0 1.6 1 0 0 1 1 1 0 DNA mismatch endonuclease Vsr Oxidored_FMN PF00724.15 EIE84335.1 - 2e-65 221.0 0.0 2.5e-65 220.7 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.12 EIE84335.1 - 0.011 14.5 0.1 0.017 13.9 0.1 1.2 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) UNC-93 PF05978.11 EIE84335.1 - 0.13 11.7 0.1 0.21 11.0 0.1 1.2 1 0 0 1 1 1 0 Ion channel regulatory protein UNC-93 THF_DHG_CYH_C PF02882.14 EIE84336.1 - 5.6e-70 233.5 0.4 6.9e-70 233.2 0.3 1.1 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 EIE84336.1 - 2.1e-19 69.6 0.9 3.7e-19 68.8 0.7 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain AdoHcyase_NAD PF00670.16 EIE84336.1 - 0.00084 19.2 0.3 0.099 12.4 0.2 2.2 1 1 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Sec1 PF00995.18 EIE84337.1 - 8.9e-91 305.2 8.1 2.4e-80 270.7 0.8 2.0 1 1 1 2 2 2 2 Sec1 family DUF853 PF05872.7 EIE84337.1 - 0.031 12.6 0.2 0.051 11.9 0.2 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) COX6A PF02046.10 EIE84343.1 - 5.5e-28 97.2 0.5 5.9e-28 97.1 0.4 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa Telomere_Sde2 PF13019.1 EIE84346.1 - 3.1e-24 85.5 0.2 3.6e-24 85.2 0.1 1.1 1 0 0 1 1 1 1 Telomere stability and silencing ubiquitin PF00240.18 EIE84346.1 - 0.00032 20.0 0.1 0.00057 19.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family GoLoco PF02188.12 EIE84346.1 - 0.17 11.2 2.4 0.22 10.8 0.2 2.2 2 0 0 2 2 2 0 GoLoco motif Fe-ADH PF00465.14 EIE84347.1 - 4.4e-28 97.9 0.0 4.8e-28 97.8 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase ATP-synt_C PF00137.16 EIE84347.1 - 0.98 9.3 4.0 0.29 11.0 0.5 1.8 2 0 0 2 2 2 0 ATP synthase subunit C RRM_1 PF00076.17 EIE84349.1 - 6.2e-19 67.3 0.3 2.8e-13 49.3 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE84349.1 - 8.7e-11 41.6 0.0 1.8e-08 34.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE84349.1 - 5.4e-05 22.9 0.1 0.05 13.4 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PfkB PF00294.19 EIE84350.1 - 1.6e-16 60.3 0.0 2.9e-12 46.3 0.0 2.0 1 1 0 2 2 2 2 pfkB family carbohydrate kinase RabGAP-TBC PF00566.13 EIE84351.1 - 1.4e-48 165.2 0.3 1.4e-48 165.2 0.2 2.9 5 0 0 5 5 5 1 Rab-GTPase-TBC domain EF-hand_7 PF13499.1 EIE84351.1 - 5.9e-05 23.1 3.8 0.00037 20.5 0.8 3.5 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.1 EIE84351.1 - 9.9e-05 21.9 3.2 0.00041 20.0 0.2 3.5 4 0 0 4 4 4 1 EF-hand domain EF-hand_1 PF00036.27 EIE84351.1 - 0.0014 17.7 0.2 0.0014 17.7 0.1 2.8 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 EIE84351.1 - 0.0038 16.7 1.6 0.0078 15.8 0.1 2.4 2 0 0 2 2 2 1 EF-hand domain pair GRAM PF02893.15 EIE84351.1 - 0.034 13.6 0.1 0.2 11.1 0.0 2.4 3 0 0 3 3 3 0 GRAM domain Cut8_N PF14482.1 EIE84354.1 - 0.011 15.6 0.2 0.057 13.4 0.0 2.0 2 0 0 2 2 2 0 Cut8 proteasome-binding domain FMO-like PF00743.14 EIE84355.1 - 5e-40 137.1 0.2 1.5e-26 92.7 0.0 3.1 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like PIP5K PF01504.13 EIE84355.1 - 5.6e-19 68.2 0.1 8.8e-19 67.5 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Pyr_redox_3 PF13738.1 EIE84355.1 - 7.2e-19 68.6 0.0 4.5e-10 39.9 0.0 2.5 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EIE84355.1 - 2.6e-07 29.9 0.0 6.2e-05 22.0 0.0 3.2 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIE84355.1 - 3e-07 30.3 0.1 1.6e-06 27.9 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EIE84355.1 - 3.3e-07 30.2 0.3 0.00043 20.0 0.0 3.7 3 1 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.12 EIE84355.1 - 5e-06 25.7 0.2 0.00051 19.2 0.0 2.5 3 0 0 3 3 3 1 Thi4 family Pyr_redox_2 PF07992.9 EIE84355.1 - 8.6e-06 25.7 0.0 0.0099 15.7 0.0 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EIE84355.1 - 7.4e-05 23.0 0.4 0.066 13.6 0.0 2.6 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 EIE84355.1 - 9.7e-05 22.5 0.0 0.29 11.4 0.0 2.7 2 0 0 2 2 2 2 Putative NAD(P)-binding K_oxygenase PF13434.1 EIE84355.1 - 0.00018 20.5 0.0 0.013 14.4 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.14 EIE84355.1 - 0.00023 20.3 0.1 0.0033 16.5 0.0 2.6 3 0 0 3 3 3 1 FAD binding domain IlvN PF07991.7 EIE84355.1 - 0.0003 20.1 0.0 0.013 14.8 0.0 2.5 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain 2-Hacid_dh_C PF02826.14 EIE84355.1 - 0.00045 19.4 0.0 0.31 10.1 0.0 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.9 EIE84355.1 - 0.00066 18.2 0.0 0.0011 17.4 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein Amino_oxidase PF01593.19 EIE84355.1 - 0.0054 15.8 0.0 0.044 12.8 0.0 2.0 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.2 EIE84355.1 - 0.011 14.8 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Shikimate_DH PF01488.15 EIE84355.1 - 0.016 15.2 0.0 6.7 6.8 0.0 3.1 4 0 0 4 4 3 0 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.18 EIE84355.1 - 0.09 12.4 0.1 0.3 10.7 0.0 1.8 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_binding_2 PF00890.19 EIE84355.1 - 0.098 11.4 0.0 0.16 10.7 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_2 PF03446.10 EIE84355.1 - 0.21 11.4 0.1 2.8 7.7 0.0 2.2 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Fe-ADH PF00465.14 EIE84356.1 - 7e-102 340.7 0.0 8.3e-102 340.5 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EIE84356.1 - 1.9e-14 53.5 0.0 5.7e-11 42.1 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.1 EIE84356.1 - 0.00025 20.4 0.1 0.00041 19.8 0.1 1.2 1 0 0 1 1 1 1 Periplasmic binding protein B12-binding PF02310.14 EIE84356.1 - 0.0005 19.9 0.0 0.001 18.9 0.0 1.4 1 0 0 1 1 1 1 B12 binding domain CobN-Mg_chel PF02514.11 EIE84356.1 - 0.2 9.0 0.0 0.24 8.7 0.0 1.1 1 0 0 1 1 1 0 CobN/Magnesium Chelatase WAC_Acf1_DNA_bd PF10537.4 EIE84357.1 - 3.6e-23 81.6 0.3 1.7e-22 79.5 0.2 2.1 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.12 EIE84357.1 - 4.3e-16 58.4 0.1 8.7e-16 57.4 0.0 1.6 1 0 0 1 1 1 1 DDT domain WHIM3 PF15614.1 EIE84357.1 - 1.2e-06 28.1 0.4 3.9e-06 26.5 0.3 1.9 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 3 Pilt PF15453.1 EIE84357.1 - 0.00038 20.2 9.1 0.00038 20.2 6.3 1.8 2 0 0 2 2 2 1 Protein incorporated later into Tight Junctions WHIM2 PF15613.1 EIE84357.1 - 0.00045 20.0 0.2 0.0013 18.5 0.1 1.8 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 Amidase_6 PF12671.2 EIE84357.1 - 0.027 14.5 0.0 0.073 13.1 0.0 1.7 1 0 0 1 1 1 0 Putative amidase domain SOBP PF15279.1 EIE84357.1 - 1.5 9.0 10.0 23 5.2 0.0 2.3 2 0 0 2 2 2 0 Sine oculis-binding protein CHD5 PF04420.9 EIE84357.1 - 8.1 6.0 6.2 1 9.0 0.7 2.2 2 0 0 2 2 2 0 CHD5-like protein CDC45 PF02724.9 EIE84357.1 - 8.9 4.2 20.2 18 3.2 14.0 1.5 1 0 0 1 1 1 0 CDC45-like protein ArfGap PF01412.13 EIE84358.1 - 5.4e-34 116.4 0.8 5.4e-34 116.4 0.6 2.5 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf PH PF00169.24 EIE84358.1 - 3.2e-12 46.5 1.1 3.2e-12 46.5 0.7 2.3 2 1 0 2 2 2 1 PH domain PH_9 PF15410.1 EIE84358.1 - 0.0035 17.4 1.4 0.027 14.6 1.0 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain MCM PF00493.18 EIE84358.1 - 0.22 10.2 3.1 0.13 11.0 0.7 1.6 2 0 0 2 2 2 0 MCM2/3/5 family DUF536 PF04394.9 EIE84358.1 - 0.43 10.3 6.2 0.14 11.8 1.2 2.6 2 0 0 2 2 2 0 Protein of unknown function, DUF536 SlyX PF04102.7 EIE84363.1 - 0.017 15.4 0.0 0.029 14.7 0.0 1.3 1 0 0 1 1 1 0 SlyX MscS_porin PF12795.2 EIE84363.1 - 0.019 14.2 1.0 0.025 13.8 0.7 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain DUF2390 PF09523.5 EIE84363.1 - 0.037 14.1 0.5 0.05 13.7 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2390) Cep57_MT_bd PF06657.8 EIE84363.1 - 0.039 13.8 1.0 0.15 12.0 0.2 1.9 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Helicase_IV_N PF12462.3 EIE84363.1 - 0.076 12.6 0.1 0.11 12.1 0.1 1.1 1 0 0 1 1 1 0 DNA helicase IV / RNA helicase N terminal DUF3890 PF13029.1 EIE84363.1 - 0.13 12.3 0.1 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3890) COMP PF11598.3 EIE84363.1 - 0.21 11.6 0.9 0.32 11.1 0.6 1.2 1 0 0 1 1 1 0 Cartilage oligomeric matrix protein Pyr_redox_2 PF07992.9 EIE84364.1 - 1e-17 64.6 0.0 1.6e-17 64.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EIE84364.1 - 1.9e-13 50.6 0.0 3.1e-07 30.6 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EIE84364.1 - 1.9e-07 30.3 0.1 4.9e-05 22.4 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 EIE84364.1 - 1.6e-05 25.0 0.0 0.0041 17.2 0.0 2.3 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EIE84364.1 - 7.5e-05 21.5 0.0 0.019 13.6 0.0 2.8 3 0 0 3 3 3 1 Tryptophan halogenase NAD_binding_7 PF13241.1 EIE84364.1 - 0.00015 21.9 0.0 0.054 13.7 0.0 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_9 PF13454.1 EIE84364.1 - 0.0011 18.8 0.1 0.14 11.8 0.0 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EIE84364.1 - 0.0018 17.2 0.0 0.85 8.4 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_8 PF13450.1 EIE84364.1 - 0.0022 17.9 0.0 0.26 11.3 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EIE84364.1 - 0.0059 15.6 0.2 1.1 8.2 0.0 2.6 3 0 0 3 3 3 1 FAD binding domain DAO PF01266.19 EIE84364.1 - 0.0085 15.0 1.2 0.023 13.6 0.8 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase TrkA_N PF02254.13 EIE84364.1 - 0.011 15.6 0.2 1.2 9.1 0.0 2.5 2 0 0 2 2 2 0 TrkA-N domain Docking PF08990.6 EIE84364.1 - 0.096 11.9 0.2 0.18 11.0 0.1 1.5 1 0 0 1 1 1 0 Erythronolide synthase docking Thi4 PF01946.12 EIE84364.1 - 0.1 11.7 0.0 0.66 9.0 0.0 2.1 2 0 0 2 2 2 0 Thi4 family Pyr_redox_2 PF07992.9 EIE84367.1 - 1e-17 64.6 0.0 1.6e-17 64.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EIE84367.1 - 1.9e-13 50.6 0.0 3.1e-07 30.6 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EIE84367.1 - 1.9e-07 30.3 0.1 4.9e-05 22.4 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 EIE84367.1 - 1.6e-05 25.0 0.0 0.0041 17.2 0.0 2.3 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EIE84367.1 - 7.5e-05 21.5 0.0 0.019 13.6 0.0 2.8 3 0 0 3 3 3 1 Tryptophan halogenase NAD_binding_7 PF13241.1 EIE84367.1 - 0.00015 21.9 0.0 0.054 13.7 0.0 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_9 PF13454.1 EIE84367.1 - 0.0011 18.8 0.1 0.14 11.8 0.0 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EIE84367.1 - 0.0018 17.2 0.0 0.85 8.4 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_8 PF13450.1 EIE84367.1 - 0.0022 17.9 0.0 0.26 11.3 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EIE84367.1 - 0.0059 15.6 0.2 1.1 8.2 0.0 2.6 3 0 0 3 3 3 1 FAD binding domain DAO PF01266.19 EIE84367.1 - 0.0085 15.0 1.2 0.023 13.6 0.8 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase TrkA_N PF02254.13 EIE84367.1 - 0.011 15.6 0.2 1.2 9.1 0.0 2.5 2 0 0 2 2 2 0 TrkA-N domain Docking PF08990.6 EIE84367.1 - 0.096 11.9 0.2 0.18 11.0 0.1 1.5 1 0 0 1 1 1 0 Erythronolide synthase docking Thi4 PF01946.12 EIE84367.1 - 0.1 11.7 0.0 0.66 9.0 0.0 2.1 2 0 0 2 2 2 0 Thi4 family GLTP PF08718.6 EIE84368.1 - 0.039 13.9 0.0 0.05 13.6 0.0 1.2 1 0 0 1 1 1 0 Glycolipid transfer protein (GLTP) Sulfate_transp PF00916.15 EIE84369.1 - 1.2e-61 208.2 10.9 1.2e-61 208.2 7.5 1.6 2 0 0 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EIE84369.1 - 3.6e-31 106.6 3.9 2.6e-30 103.8 2.7 2.6 1 0 0 1 1 1 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EIE84369.1 - 1.7e-09 37.1 0.0 3.6e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 EIE84369.1 - 8.9e-05 22.4 0.0 0.002 18.1 0.0 2.4 2 0 0 2 2 2 1 STAS domain HLH PF00010.21 EIE84370.1 - 2.8e-19 68.5 1.8 5.7e-19 67.5 0.7 2.1 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain OGG_N PF07934.7 EIE84370.1 - 1.6 8.6 7.6 3.7 7.5 0.1 3.7 3 0 0 3 3 3 0 8-oxoguanine DNA glycosylase, N-terminal domain Pkinase PF00069.20 EIE84371.1 - 1.7e-50 171.5 0.1 1.8e-25 89.5 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIE84371.1 - 4.2e-21 75.2 0.1 4e-13 49.0 0.3 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EIE84371.1 - 0.0079 15.1 0.0 0.026 13.4 0.0 1.8 2 0 0 2 2 2 1 Kinase-like DUF764 PF05561.6 EIE84371.1 - 0.021 14.2 0.0 0.043 13.2 0.0 1.5 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF764) Pkinase PF00069.20 EIE84373.1 - 3.5e-17 62.4 1.2 4.2e-17 62.1 0.8 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE84373.1 - 5.4e-09 35.5 0.5 5.7e-09 35.4 0.4 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Act-Frag_cataly PF09192.5 EIE84373.1 - 0.057 12.3 0.0 0.067 12.1 0.0 1.1 1 0 0 1 1 1 0 Actin-fragmin kinase, catalytic PAZ PF02170.17 EIE84373.1 - 0.062 12.5 0.5 1.1 8.5 0.1 2.1 1 1 1 2 2 2 0 PAZ domain XPA_C PF05181.7 EIE84373.1 - 0.07 12.7 0.0 2 8.0 0.0 2.1 2 0 0 2 2 2 0 XPA protein C-terminus WD40 PF00400.27 EIE84375.1 - 1.8e-48 160.7 15.2 1.1e-10 41.0 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat Tup_N PF08581.5 EIE84375.1 - 2.7e-11 43.4 14.1 2.7e-11 43.4 9.8 3.6 2 2 0 2 2 1 1 Tup N-terminal SprA-related PF12118.3 EIE84375.1 - 0.0012 18.2 36.5 0.0012 18.2 25.3 2.0 2 0 0 2 2 2 1 SprA-related family eIF-3_zeta PF05091.7 EIE84375.1 - 0.0034 16.0 15.9 0.0058 15.3 11.0 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SPX PF03105.14 EIE84375.1 - 0.0069 16.1 14.6 0.017 14.9 5.7 2.4 2 0 0 2 2 2 1 SPX domain HlyD_2 PF12700.2 EIE84375.1 - 0.019 14.1 17.0 0.59 9.2 10.5 2.1 2 0 0 2 2 2 0 HlyD family secretion protein Nbas_N PF15492.1 EIE84375.1 - 0.02 13.9 0.1 5.7 5.9 0.0 2.8 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal AvrE PF11725.3 EIE84375.1 - 0.12 9.3 21.9 0.21 8.6 15.2 1.2 1 0 0 1 1 1 0 Pathogenicity factor AMP-binding PF00501.23 EIE84375.1 - 0.18 10.1 1.0 0.26 9.6 0.7 1.2 1 0 0 1 1 1 0 AMP-binding enzyme AAA_11 PF13086.1 EIE84375.1 - 0.19 11.2 20.2 0.061 12.8 8.1 2.3 2 0 0 2 2 2 0 AAA domain Mem_trans PF03547.13 EIE84375.1 - 0.83 7.8 4.4 1.1 7.4 3.1 1.2 1 0 0 1 1 1 0 Membrane transport protein V_ATPase_I PF01496.14 EIE84375.1 - 2.5 5.8 17.2 2.3 5.9 0.1 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family LMBR1 PF04791.11 EIE84375.1 - 2.8 6.3 5.4 4.8 5.6 3.7 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Ycf1 PF05758.7 EIE84375.1 - 3.4 5.2 20.3 0.015 13.0 8.0 1.4 2 0 0 2 2 2 0 Ycf1 SR-25 PF10500.4 EIE84375.1 - 3.6 6.9 26.2 6.9 6.0 18.2 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SAGA-Tad1 PF12767.2 EIE84375.1 - 7.2 6.2 37.3 0.24 11.0 21.0 1.9 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit AUX_IAA PF02309.11 EIE84375.1 - 8.8 6.0 19.4 0.58 9.8 9.9 1.6 2 0 0 2 2 2 0 AUX/IAA family ATG22 PF11700.3 EIE84375.1 - 9.1 4.6 4.9 14 4.0 3.4 1.2 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like DUF925 PF06042.6 EIE84376.1 - 0.11 12.1 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF925) DivIC PF04977.10 EIE84377.1 - 0.0084 15.5 0.4 0.017 14.5 0.3 1.4 1 0 0 1 1 1 1 Septum formation initiator SlyX PF04102.7 EIE84377.1 - 0.013 15.8 0.7 0.028 14.7 0.5 1.6 1 0 0 1 1 1 0 SlyX Lebercilin PF15619.1 EIE84377.1 - 0.068 12.5 2.0 0.11 11.8 1.4 1.3 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Cep57_CLD_2 PF14197.1 EIE84377.1 - 0.3 11.0 3.6 0.69 9.9 1.0 2.2 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 zf-CCHC PF00098.18 EIE84378.1 - 5.6e-05 22.8 1.0 5.6e-05 22.8 0.7 2.9 3 0 0 3 3 3 1 Zinc knuckle RRM_1 PF00076.17 EIE84378.1 - 0.074 12.6 0.0 0.35 10.5 0.0 2.1 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC_2 PF13696.1 EIE84378.1 - 0.23 11.0 3.3 0.59 9.6 0.3 2.3 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC_6 PF15288.1 EIE84378.1 - 0.83 9.3 7.4 0.31 10.7 1.2 2.6 1 1 1 2 2 2 0 Zinc knuckle RVT_1 PF00078.22 EIE84379.1 - 3.5e-33 114.7 0.2 7.4e-32 110.4 0.0 2.2 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.1 EIE84380.1 - 3.7e-07 30.3 0.6 3.7e-07 30.3 0.4 1.7 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase Stork_head PF10264.4 EIE84383.1 - 0.13 12.4 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 Winged helix Storkhead-box1 domain CP2 PF04516.10 EIE84386.1 - 5.8e-35 120.4 0.5 6.6e-32 110.4 0.4 2.2 1 1 0 1 1 1 1 CP2 transcription factor Adaptin_N PF01602.15 EIE84387.1 - 9.1e-108 360.8 6.8 1.3e-107 360.2 4.7 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 EIE84387.1 - 6.9e-69 229.5 0.1 1.6e-68 228.3 0.1 1.7 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 EIE84387.1 - 9.5e-60 200.3 0.7 2.3e-59 199.0 0.5 1.7 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 EIE84387.1 - 1.4e-15 57.3 2.7 3.7e-07 30.3 0.0 4.8 3 1 0 4 4 4 3 HEAT repeats HEAT PF02985.17 EIE84387.1 - 1.5e-06 27.8 0.0 0.013 15.5 0.0 4.4 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.1 EIE84387.1 - 5.4e-05 23.5 0.5 0.038 14.4 0.0 4.2 4 0 0 4 4 4 1 HEAT-like repeat Cnd1 PF12717.2 EIE84387.1 - 0.00022 21.1 10.7 0.093 12.5 0.0 4.8 3 1 2 5 5 5 3 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 EIE84387.1 - 0.19 11.6 1.8 41 4.2 0.0 4.8 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat WD40 PF00400.27 EIE84388.1 - 7.7e-23 79.4 5.9 0.00042 20.0 0.0 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 EIE84388.1 - 0.00035 18.8 0.5 0.075 11.1 0.0 2.6 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Kelch_5 PF13854.1 EIE84389.1 - 8.1e-13 48.0 9.4 8.9e-06 25.5 0.0 3.9 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 EIE84389.1 - 1.9e-10 40.3 11.0 0.00073 19.2 0.2 4.7 4 1 0 4 4 4 2 Galactose oxidase, central domain Kelch_3 PF13415.1 EIE84389.1 - 1e-09 38.2 6.6 0.0008 19.5 0.3 3.8 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_2 PF07646.10 EIE84389.1 - 1.9e-08 33.7 4.3 0.0074 16.0 0.1 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 EIE84389.1 - 2e-07 30.8 5.5 0.0061 16.6 0.1 3.6 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 EIE84389.1 - 3.6e-07 29.6 14.1 0.0048 16.4 1.8 4.3 4 1 0 4 4 4 2 Kelch motif zf-CCHC PF00098.18 EIE84390.1 - 7.3e-09 35.1 6.5 0.0012 18.6 1.3 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 EIE84390.1 - 0.011 15.4 6.5 0.23 11.1 0.3 2.5 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.1 EIE84390.1 - 0.5 9.9 3.3 0.53 9.8 0.5 2.1 1 1 1 2 2 2 0 Zinc knuckle Cmc1 PF08583.5 EIE84390.1 - 0.54 10.0 5.8 0.28 10.9 2.4 1.6 2 0 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like zinc-ribbons_6 PF07191.7 EIE84390.1 - 0.64 9.8 8.7 0.11 12.2 3.0 1.9 2 0 0 2 2 2 0 zinc-ribbons RVT_1 PF00078.22 EIE84392.1 - 8.3e-27 93.9 0.1 1.9e-26 92.7 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.1 EIE84392.1 - 1.7e-06 28.2 1.5 1.7e-06 28.2 1.1 2.5 3 0 0 3 3 3 1 zinc-binding in reverse transcriptase Stork_head PF10264.4 EIE84394.1 - 0.13 12.4 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 Winged helix Storkhead-box1 domain DivIVA PF05103.8 EIE84395.1 - 0.00018 21.5 5.4 0.00038 20.5 3.7 1.5 1 0 0 1 1 1 1 DivIVA protein TMF_TATA_bd PF12325.3 EIE84395.1 - 0.00019 21.1 1.2 0.00038 20.1 0.8 1.5 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding CENP-F_leu_zip PF10473.4 EIE84395.1 - 0.0025 17.6 3.7 0.0025 17.6 2.6 1.7 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Golgin_A5 PF09787.4 EIE84395.1 - 0.0026 16.3 5.5 0.0041 15.6 3.8 1.4 1 1 0 1 1 1 1 Golgin subfamily A member 5 DUF948 PF06103.6 EIE84395.1 - 0.003 17.3 1.7 0.0052 16.6 1.2 1.3 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF948) DUF3450 PF11932.3 EIE84395.1 - 0.011 15.0 8.1 0.011 15.0 5.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) FliJ PF02050.11 EIE84395.1 - 0.014 15.3 5.6 0.014 15.3 3.9 2.1 2 0 0 2 2 2 0 Flagellar FliJ protein CCDC144C PF14915.1 EIE84395.1 - 0.025 13.4 6.5 0.039 12.8 4.5 1.3 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region Filament PF00038.16 EIE84395.1 - 0.037 13.5 5.0 0.074 12.5 3.5 1.4 1 0 0 1 1 1 0 Intermediate filament protein TMF_DNA_bd PF12329.3 EIE84395.1 - 0.05 13.4 2.6 0.13 12.1 1.8 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding FUSC PF04632.7 EIE84395.1 - 0.08 11.3 4.1 0.094 11.1 2.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Striatin PF08232.7 EIE84395.1 - 0.23 11.7 8.0 4.3 7.6 1.5 3.0 2 1 1 3 3 3 0 Striatin family DUF3365 PF11845.3 EIE84395.1 - 0.28 11.0 3.2 0.42 10.4 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3365) TBPIP PF07106.8 EIE84395.1 - 0.29 10.6 5.3 0.083 12.4 1.7 1.6 2 0 0 2 2 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) GrpE PF01025.14 EIE84395.1 - 0.33 10.4 4.2 0.3 10.6 0.7 2.4 3 1 0 3 3 3 0 GrpE DUF4407 PF14362.1 EIE84395.1 - 0.42 9.5 5.8 0.6 9.0 4.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AATF-Che1 PF13339.1 EIE84395.1 - 0.44 10.6 5.8 0.3 11.2 1.9 2.1 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor CorA PF01544.13 EIE84395.1 - 0.64 9.0 3.5 1.6 7.7 2.4 1.6 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein V_ATPase_I PF01496.14 EIE84395.1 - 0.72 7.6 2.3 0.91 7.2 1.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIC PF04977.10 EIE84395.1 - 0.86 9.1 8.4 0.11 11.9 2.7 1.8 2 0 0 2 2 2 0 Septum formation initiator APG6 PF04111.7 EIE84395.1 - 1.6 7.7 6.8 2.3 7.1 4.7 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Atg14 PF10186.4 EIE84395.1 - 1.6 7.5 11.1 3.1 6.6 7.5 1.6 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Mnd1 PF03962.10 EIE84395.1 - 2.3 7.8 6.4 5 6.7 4.4 1.6 1 1 0 1 1 1 0 Mnd1 family DUF4140 PF13600.1 EIE84395.1 - 5.5 7.4 7.4 1.3 9.5 1.4 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) ADIP PF11559.3 EIE84395.1 - 9.2 6.1 18.2 4.5 7.1 6.1 2.7 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding JAB PF01398.16 EIE84398.1 - 0.14 11.9 1.9 1.1 9.0 1.3 2.3 1 1 0 1 1 1 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Sec1 PF00995.18 EIE84399.1 - 0.051 12.2 0.0 0.053 12.1 0.0 1.0 1 0 0 1 1 1 0 Sec1 family AMP-binding PF00501.23 EIE84401.1 - 8.8e-82 274.7 0.0 1.3e-81 274.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Fungal_trans PF04082.13 EIE84401.1 - 3e-21 75.4 1.4 3e-21 75.4 1.0 2.7 3 0 0 3 3 3 1 Fungal specific transcription factor domain AMP-binding_C PF13193.1 EIE84401.1 - 2.3e-16 60.4 0.1 1.2e-15 58.2 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Zn_clus PF00172.13 EIE84401.1 - 0.0079 16.0 6.0 0.015 15.1 4.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Voltage_CLC PF00654.15 EIE84401.1 - 0.51 9.3 0.0 0.85 8.5 0.0 1.2 1 0 0 1 1 1 0 Voltage gated chloride channel SPARC_Ca_bdg PF10591.4 EIE84402.1 - 0.018 15.0 0.2 0.037 14.0 0.1 1.5 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region I_LWEQ PF01608.12 EIE84405.1 - 2.3e-57 193.2 11.0 2.3e-57 193.2 7.6 5.0 4 1 0 5 5 5 1 I/LWEQ domain ANTH PF07651.11 EIE84405.1 - 2.4e-52 177.4 1.0 1.1e-50 171.9 0.0 4.3 3 2 1 4 4 4 2 ANTH domain zf-C2H2 PF00096.21 EIE84406.1 - 0.00058 20.0 5.2 0.33 11.3 0.6 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type DUF629 PF04780.7 EIE84406.1 - 0.0024 16.4 0.4 0.22 10.0 0.1 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF629) zf-C2H2_2 PF12756.2 EIE84406.1 - 0.0044 17.1 0.3 0.1 12.7 0.0 2.1 1 1 1 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 EIE84406.1 - 0.022 15.0 6.2 1.9 9.0 0.3 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger OSTMP1 PF09777.4 EIE84406.1 - 0.039 13.1 0.1 0.051 12.7 0.0 1.1 1 0 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor Eapp_C PF10238.4 EIE84406.1 - 0.039 13.8 0.6 0.056 13.3 0.4 1.2 1 0 0 1 1 1 0 E2F-associated phosphoprotein zf-H2C2_2 PF13465.1 EIE84406.1 - 0.042 14.1 2.2 0.042 14.1 1.5 3.0 3 0 0 3 3 3 0 Zinc-finger double domain zf-Di19 PF05605.7 EIE84406.1 - 0.097 12.8 4.4 0.77 9.9 2.3 2.6 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding CLTH PF10607.4 EIE84409.1 - 2.8e-34 117.8 0.7 2.8e-34 117.8 0.5 1.6 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 EIE84409.1 - 0.00073 19.2 0.0 0.0018 17.9 0.0 1.7 1 0 0 1 1 1 1 LisH ACCA PF03255.9 EIE84409.1 - 0.14 11.6 2.8 3.4 7.2 0.0 2.3 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit LLC1 PF14945.1 EIE84409.1 - 0.18 12.1 3.0 6.2 7.1 1.0 2.7 1 1 1 2 2 2 0 Normal lung function maintenance, Low in Lung Cancer 1 protein Trns_repr_metal PF02583.12 EIE84409.1 - 0.3 11.2 5.0 2.2 8.5 0.1 3.1 3 0 0 3 3 3 0 Metal-sensitive transcriptional repressor Orthopox_A5L PF06193.6 EIE84409.1 - 0.32 10.9 5.2 0.68 9.8 0.5 2.4 1 1 1 2 2 2 0 Orthopoxvirus A5L protein-like Glyco_hydro_72 PF03198.9 EIE84410.1 - 0.093 11.7 0.1 0.093 11.7 0.0 1.0 1 0 0 1 1 1 0 Glucanosyltransferase PGM_PMM_I PF02878.11 EIE84411.1 - 2.9e-35 120.7 0.1 4.8e-35 120.0 0.1 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 EIE84411.1 - 8.9e-29 99.8 0.0 5.2e-28 97.3 0.0 2.1 2 1 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 EIE84411.1 - 2.7e-14 53.3 0.1 8.1e-14 51.8 0.1 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EIE84411.1 - 1.7e-11 43.9 0.0 4.6e-11 42.5 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Autophagy_N PF03986.8 EIE84412.1 - 4e-47 159.6 3.4 9.9e-47 158.3 2.4 1.7 1 1 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 EIE84412.1 - 3.3e-27 94.4 0.8 3.3e-27 94.4 0.6 2.3 3 0 0 3 3 3 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 EIE84412.1 - 1.5e-13 49.5 3.0 2.7e-13 48.7 2.1 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Nop14 PF04147.7 EIE84412.1 - 1.5 6.6 16.5 0.15 9.9 0.4 2.0 2 0 0 2 2 2 0 Nop14-like family DUF1900 PF08954.6 EIE84413.1 - 1.1e-54 183.6 0.0 1.8e-54 182.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 EIE84413.1 - 3.1e-31 106.8 0.2 5.3e-31 106.0 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 EIE84413.1 - 2.6e-27 93.6 0.2 2e-07 30.6 0.0 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat LEA_2 PF03168.8 EIE84414.1 - 7.4e-06 26.2 0.1 1.1e-05 25.6 0.0 1.2 1 0 0 1 1 1 1 Late embryogenesis abundant protein TIG PF01833.19 EIE84414.1 - 0.12 12.3 2.4 0.12 12.3 0.5 2.0 2 1 0 2 2 2 0 IPT/TIG domain Pyr_redox PF00070.22 EIE84415.1 - 7.4e-08 32.6 0.0 1.4e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EIE84415.1 - 1.1e-06 28.7 0.0 1.9e-06 27.9 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EIE84415.1 - 0.0039 16.1 0.0 0.0056 15.6 0.0 1.2 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 EIE84415.1 - 0.025 14.6 0.0 0.068 13.2 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EIE84415.1 - 0.038 12.9 0.0 0.079 11.8 0.0 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_8 PF13450.1 EIE84415.1 - 0.048 13.6 0.0 0.13 12.2 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain THF_DHG_CYH_C PF02882.14 EIE84415.1 - 0.11 11.6 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DAO PF01266.19 EIE84415.1 - 0.13 11.1 0.0 0.63 8.8 0.0 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase Cation_efflux PF01545.16 EIE84416.1 - 3.5e-65 219.8 8.4 9.7e-63 211.8 0.7 2.0 1 1 1 2 2 2 2 Cation efflux family NicO PF03824.11 EIE84416.1 - 0.0026 17.1 0.0 0.0066 15.8 0.0 1.6 1 1 0 1 1 1 1 High-affinity nickel-transport protein Transport_MerF PF11431.3 EIE84416.1 - 5.5 6.7 7.6 0.77 9.4 2.2 1.9 2 0 0 2 2 2 0 Membrane transport protein MerF Arrestin_N PF00339.24 EIE84417.1 - 1.5e-20 73.5 0.0 3.1e-20 72.5 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EIE84417.1 - 3.3e-19 69.3 0.1 1e-15 58.0 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.2 EIE84417.1 - 0.00027 20.4 0.0 0.00056 19.4 0.0 1.6 1 0 0 1 1 1 1 Arrestin_N terminal like WD40 PF00400.27 EIE84419.1 - 1.5e-33 113.4 3.3 2.7e-07 30.2 0.2 6.3 6 1 1 7 7 7 4 WD domain, G-beta repeat eIF2A PF08662.6 EIE84419.1 - 1.6e-05 24.7 0.2 0.025 14.2 0.0 2.4 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 EIE84419.1 - 0.0062 16.0 0.0 3.2 7.3 0.0 3.1 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Glyco_transf_15 PF01793.11 EIE84420.1 - 1.7e-116 388.7 12.5 2.2e-116 388.4 8.7 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Me-amine-dh_L PF02975.9 EIE84421.1 - 0.07 13.1 0.1 0.083 12.8 0.0 1.1 1 0 0 1 1 1 0 Methylamine dehydrogenase, L chain Myb_DNA-binding PF00249.26 EIE84422.1 - 4.4e-20 71.4 6.4 8.2e-10 38.5 0.5 3.4 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EIE84422.1 - 2.4e-17 62.7 9.7 1e-08 35.1 0.9 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.4 EIE84422.1 - 0.015 15.4 7.4 0.061 13.5 0.3 3.0 2 2 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF4085 PF13315.1 EIE84422.1 - 0.022 14.1 3.6 0.47 9.7 0.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4085) Myb_DNA-bind_5 PF13873.1 EIE84422.1 - 3 7.8 7.0 30 4.6 0.1 4.0 4 1 1 5 5 5 0 Myb/SANT-like DNA-binding domain Xan_ur_permease PF00860.15 EIE84423.1 - 5.1e-60 202.9 36.4 1.7e-58 197.9 25.3 2.2 1 1 0 1 1 1 1 Permease family Myc_N PF01056.13 EIE84424.1 - 0.00027 20.2 3.8 0.00047 19.4 2.7 1.4 1 0 0 1 1 1 1 Myc amino-terminal region zf-C2H2 PF00096.21 EIE84424.1 - 0.0013 18.8 6.2 0.0013 18.8 4.3 2.2 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIE84424.1 - 0.06 13.7 6.6 0.2 12.0 4.5 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger ClpS PF02617.12 EIE84425.1 - 6.4e-08 32.2 0.2 2.9e-07 30.0 0.0 2.2 2 0 0 2 2 2 1 ATP-dependent Clp protease adaptor protein ClpS PEMT PF04191.8 EIE84426.1 - 1.2e-50 169.9 20.0 2e-31 108.2 1.2 2.9 3 0 0 3 3 3 2 Phospholipid methyltransferase Acyl-CoA_dh_C PF12806.2 EIE84426.1 - 0.095 12.5 0.1 0.16 11.7 0.1 1.4 1 0 0 1 1 1 0 Acetyl-CoA dehydrogenase C-terminal like DUF883 PF05957.8 EIE84426.1 - 0.15 12.4 0.7 0.3 11.5 0.5 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.13 EIE84426.1 - 0.32 10.4 1.9 0.48 9.9 1.3 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain TBCA PF02970.11 EIE84426.1 - 1.1 9.3 4.3 6.7 6.8 1.4 2.3 1 1 1 2 2 2 0 Tubulin binding cofactor A ADH_N PF08240.7 EIE84427.1 - 1.6e-23 82.5 3.0 2.5e-23 81.9 2.1 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIE84427.1 - 9.9e-17 60.7 0.0 1.5e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EIE84427.1 - 0.0038 16.3 0.0 0.0057 15.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_11 PF08241.7 EIE84428.1 - 2.2e-05 24.8 0.0 3.5e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIE84428.1 - 2.2e-05 24.2 0.0 3.3e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIE84428.1 - 0.00026 20.6 0.0 0.00045 19.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIE84428.1 - 0.0042 17.5 0.0 0.0068 16.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Peptidase_S24 PF00717.18 EIE84430.1 - 2.4e-09 36.6 0.0 6e-09 35.4 0.0 1.7 1 1 0 1 1 1 1 Peptidase S24-like NAP PF00956.13 EIE84431.1 - 0.041 13.0 0.1 0.045 12.8 0.0 1.2 1 0 0 1 1 1 0 Nucleosome assembly protein (NAP) AIG1 PF04548.11 EIE84432.1 - 5.2e-16 58.3 4.1 8.1e-14 51.2 2.8 2.4 1 1 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.18 EIE84432.1 - 7.2e-08 32.4 0.1 2.2e-07 30.8 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EIE84432.1 - 1.9e-06 27.8 0.8 0.018 14.9 0.1 2.4 1 1 1 2 2 2 2 Dynamin family DUF258 PF03193.11 EIE84432.1 - 0.00024 20.3 0.2 0.027 13.6 0.1 2.3 1 1 1 2 2 2 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 EIE84432.1 - 0.003 17.8 0.3 0.0041 17.4 0.2 1.4 1 1 0 1 1 1 1 ABC transporter Amidohydro_4 PF13147.1 EIE84432.1 - 0.018 15.1 0.0 0.024 14.6 0.0 1.1 1 0 0 1 1 1 0 Amidohydrolase AAA_18 PF13238.1 EIE84432.1 - 0.028 14.7 0.0 0.073 13.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain GBP PF02263.14 EIE84432.1 - 0.07 12.1 0.7 0.52 9.3 0.0 2.4 2 1 1 3 3 3 0 Guanylate-binding protein, N-terminal domain AAA_29 PF13555.1 EIE84432.1 - 0.093 12.2 0.1 0.2 11.2 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Myelin_PLP PF01275.14 EIE84432.1 - 0.095 12.0 0.1 0.16 11.3 0.1 1.3 1 0 0 1 1 1 0 Myelin proteolipid protein (PLP or lipophilin) Acetyltransf_4 PF13420.1 EIE84433.1 - 4.9e-24 85.0 0.1 5.7e-24 84.8 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EIE84433.1 - 1.3e-12 48.1 0.0 1.5e-12 47.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EIE84433.1 - 1.2e-10 41.2 0.0 1.8e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EIE84433.1 - 2e-05 24.2 0.1 3.7e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EIE84433.1 - 0.0013 18.8 0.0 0.002 18.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EIE84433.1 - 0.0088 16.1 0.0 0.016 15.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Mec-17 PF05301.6 EIE84433.1 - 0.0098 15.8 0.0 0.023 14.6 0.0 1.6 1 0 0 1 1 1 1 Touch receptor neuron protein Mec-17 Acetyltransf_9 PF13527.1 EIE84433.1 - 0.029 14.2 0.7 0.19 11.5 0.5 2.0 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain CRCB PF02537.10 EIE84434.1 - 6.3e-32 109.9 23.8 5.6e-18 64.9 9.3 2.7 2 1 0 2 2 2 2 CrcB-like protein DEAD PF00270.24 EIE84435.1 - 1.2e-36 125.6 0.2 2.5e-36 124.7 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIE84435.1 - 8.3e-27 92.8 0.0 1.8e-25 88.6 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIE84435.1 - 0.00032 20.5 0.2 0.0011 18.8 0.0 2.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 EIE84435.1 - 0.0096 15.0 0.0 0.021 13.9 0.0 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit IATP PF04568.7 EIE84436.1 - 6.6e-08 32.4 0.6 7.6e-08 32.2 0.4 1.1 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP NYD-SP28 PF14772.1 EIE84436.1 - 0.0034 17.4 0.4 0.0044 17.0 0.3 1.2 1 0 0 1 1 1 1 Sperm tail DUF2188 PF09954.4 EIE84436.1 - 0.033 14.1 1.8 0.057 13.3 1.3 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2188) Atg14 PF10186.4 EIE84436.1 - 0.059 12.3 1.2 0.056 12.3 0.9 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF802 PF05650.6 EIE84436.1 - 0.12 12.4 2.0 0.19 11.8 1.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF802) TMF_DNA_bd PF12329.3 EIE84436.1 - 0.14 11.9 5.9 0.11 12.3 3.2 1.5 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding XhlA PF10779.4 EIE84436.1 - 0.62 10.0 2.9 0.88 9.5 2.0 1.3 1 0 0 1 1 1 0 Haemolysin XhlA BTB PF00651.26 EIE84437.1 - 6.8e-29 100.0 5.3 3.3e-13 49.5 0.0 3.5 3 0 0 3 3 3 2 BTB/POZ domain Ank_2 PF12796.2 EIE84437.1 - 3.7e-09 36.8 0.2 9.6e-09 35.4 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EIE84437.1 - 2.4e-08 33.4 0.1 7.8e-06 25.6 0.0 3.2 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.25 EIE84437.1 - 3.1e-08 33.0 0.0 1.9e-06 27.4 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 EIE84437.1 - 1e-07 31.9 0.2 1.4e-06 28.3 0.3 2.5 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 EIE84437.1 - 7.1e-07 29.5 0.0 1.9e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) bZIP_1 PF00170.16 EIE84439.1 - 0.0024 17.8 9.4 0.0043 16.9 6.5 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EIE84439.1 - 0.017 14.9 8.7 0.017 14.9 6.0 1.9 2 1 0 2 2 2 0 Basic region leucine zipper FYRN PF05964.9 EIE84440.1 - 1.7e-20 72.1 0.1 2.6e-20 71.6 0.1 1.3 1 0 0 1 1 1 1 F/Y-rich N-terminus FYRC PF05965.9 EIE84440.1 - 1.7e-20 72.5 0.0 3.5e-20 71.5 0.0 1.5 1 0 0 1 1 1 1 F/Y rich C-terminus Crystall PF00030.14 EIE84440.1 - 0.017 15.0 0.1 0.12 12.2 0.0 2.1 1 1 1 2 2 2 0 Beta/Gamma crystallin RtcB PF01139.12 EIE84440.1 - 0.02 13.9 0.9 0.026 13.5 0.7 1.1 1 0 0 1 1 1 0 tRNA-splicing ligase RtcB BUD22 PF09073.5 EIE84440.1 - 0.034 13.2 10.8 0.047 12.7 7.5 1.1 1 0 0 1 1 1 0 BUD22 TFIIA PF03153.8 EIE84440.1 - 0.12 12.1 8.9 0.18 11.7 6.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DDHD PF02862.12 EIE84440.1 - 0.23 11.2 2.8 0.31 10.8 2.0 1.2 1 0 0 1 1 1 0 DDHD domain Cwf_Cwc_15 PF04889.7 EIE84440.1 - 0.29 10.8 14.3 0.44 10.2 9.9 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CK_II_beta PF01214.13 EIE84442.1 - 5.7e-49 166.1 0.2 7.5e-49 165.7 0.1 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Dynactin_p62 PF05502.8 EIE84442.1 - 6.4 5.4 6.8 10 4.7 4.7 1.3 1 0 0 1 1 1 0 Dynactin p62 family RPAP2_Rtr1 PF04181.8 EIE84443.1 - 1.1e-21 76.6 1.6 1.1e-21 76.6 1.1 2.3 2 0 0 2 2 2 1 Rtr1/RPAP2 family Coq4 PF05019.8 EIE84444.1 - 1.7e-89 298.5 0.0 2e-89 298.3 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 Pacifastin_I PF05375.8 EIE84445.1 - 1.7e-07 30.5 6.9 1.7e-07 30.5 4.8 2.6 1 1 1 2 2 2 2 Pacifastin inhibitor (LCMII) VWC PF00093.13 EIE84445.1 - 6.9 6.8 13.1 0.8 9.8 5.9 1.8 1 1 1 2 2 2 0 von Willebrand factor type C domain DDE_3 PF13358.1 EIE84446.1 - 3.7e-18 65.6 0.0 4.1e-18 65.5 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EIE84448.1 - 3.7e-18 65.6 0.0 4.1e-18 65.5 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Chromo PF00385.19 EIE84449.1 - 1.4e-05 24.6 1.6 2.2e-05 24.0 1.1 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF2040 PF09745.4 EIE84452.1 - 0.072 12.9 0.2 0.11 12.3 0.2 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 55 (DUF2040) EF-hand_7 PF13499.1 EIE84453.1 - 0.11 12.5 0.1 0.19 11.8 0.0 1.6 1 1 0 1 1 1 0 EF-hand domain pair DDE_Tnp_IS1595 PF12762.2 EIE84454.1 - 8.2e-15 54.9 0.0 5.6e-09 35.9 0.0 2.8 1 1 1 2 2 2 2 ISXO2-like transposase domain Leader_Erm PF08253.6 EIE84455.1 - 4.2 6.9 5.5 1 8.8 1.0 2.1 2 0 0 2 2 2 0 Erm Leader peptide DDE_3 PF13358.1 EIE84457.1 - 5.6e-14 52.1 0.0 8.9e-14 51.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE84458.1 - 1.5e-16 60.2 1.9 5.1e-16 58.4 0.2 2.3 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 EIE84458.1 - 5.7e-09 36.1 0.1 1.3e-08 34.9 0.1 1.6 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EIE84458.1 - 1.5e-08 33.9 0.0 1.1e-05 24.8 0.0 2.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_7 PF02796.10 EIE84458.1 - 2.3e-07 30.5 5.5 8.8e-06 25.4 0.4 3.2 2 1 0 2 2 2 1 Helix-turn-helix domain of resolvase DDE_3 PF13358.1 EIE84458.1 - 4.2e-07 29.8 0.0 7.7e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.1 EIE84458.1 - 3.1e-06 27.8 0.8 2.4e-05 25.0 0.0 2.7 2 1 1 3 3 2 1 Homeodomain-like domain HTH_11 PF08279.7 EIE84458.1 - 4.9e-06 26.0 1.2 0.00046 19.7 0.1 2.6 2 1 0 2 2 2 1 HTH domain HTH_36 PF13730.1 EIE84458.1 - 5.8e-06 26.3 1.3 0.00023 21.2 0.3 2.9 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_38 PF13936.1 EIE84458.1 - 9.2e-05 21.9 0.6 0.00075 19.0 0.0 2.4 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_28 PF13518.1 EIE84458.1 - 0.00014 21.7 0.0 0.026 14.5 0.0 2.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.1 EIE84458.1 - 0.00016 20.7 0.1 0.1 11.8 0.0 2.8 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_33 PF13592.1 EIE84458.1 - 0.00016 21.1 0.2 0.00046 19.6 0.0 1.9 2 0 0 2 2 1 1 Winged helix-turn helix HTH_24 PF13412.1 EIE84458.1 - 0.00025 20.3 0.6 0.017 14.5 0.1 2.8 3 0 0 3 3 2 1 Winged helix-turn-helix DNA-binding HTH_21 PF13276.1 EIE84458.1 - 0.00053 19.9 0.0 0.0023 17.8 0.0 2.0 2 0 0 2 2 2 1 HTH-like domain LacI PF00356.16 EIE84458.1 - 0.0012 18.3 0.6 1.1 8.8 0.0 2.5 2 0 0 2 2 2 2 Bacterial regulatory proteins, lacI family GerE PF00196.14 EIE84458.1 - 0.003 16.8 0.2 0.0084 15.4 0.1 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family TrmB PF01978.14 EIE84458.1 - 0.0041 16.8 0.3 0.05 13.3 0.1 2.4 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_AsnC-type PF13404.1 EIE84458.1 - 0.0042 16.5 0.1 0.011 15.1 0.0 1.7 2 0 0 2 2 1 1 AsnC-type helix-turn-helix domain KorB PF08535.5 EIE84458.1 - 0.0058 16.7 0.1 0.015 15.4 0.0 1.6 1 0 0 1 1 1 1 KorB domain HTH_6 PF01418.12 EIE84458.1 - 0.006 16.2 0.7 0.64 9.7 0.1 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain, rpiR family GntR PF00392.16 EIE84458.1 - 0.007 15.7 0.1 1.3 8.5 0.0 2.6 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family Trp_repressor PF01371.14 EIE84458.1 - 0.012 15.5 0.3 0.039 13.8 0.1 1.9 2 0 0 2 2 1 0 Trp repressor protein HTH_3 PF01381.17 EIE84458.1 - 0.013 15.3 0.7 0.2 11.5 0.2 2.2 2 0 0 2 2 2 0 Helix-turn-helix Phage_terminase PF10668.4 EIE84458.1 - 0.014 15.2 0.1 0.014 15.2 0.1 1.9 2 0 0 2 2 1 0 Phage terminase small subunit Sigma54_DBD PF04552.8 EIE84458.1 - 0.028 13.9 1.2 0.21 11.1 0.1 2.5 3 0 0 3 3 2 0 Sigma-54, DNA binding domain HTH_40 PF14493.1 EIE84458.1 - 0.03 14.5 0.0 0.063 13.4 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Acetyltransf_2 PF00797.12 EIE84458.1 - 0.077 12.5 0.4 11 5.4 0.1 2.5 2 1 1 3 3 3 0 N-acetyltransferase HTH_10 PF04967.7 EIE84458.1 - 0.086 12.4 0.1 1.5 8.4 0.0 2.3 2 0 0 2 2 2 0 HTH DNA binding domain HTH_5 PF01022.15 EIE84458.1 - 0.094 12.3 0.1 1.3 8.7 0.0 2.4 2 1 0 2 2 2 0 Bacterial regulatory protein, arsR family Fe_dep_repress PF01325.14 EIE84458.1 - 0.12 12.3 1.5 1.6 8.7 0.1 2.8 3 0 0 3 3 3 0 Iron dependent repressor, N-terminal DNA binding domain Sigma70_r4_2 PF08281.7 EIE84458.1 - 0.12 11.8 0.5 1.5 8.3 0.1 2.3 2 0 0 2 2 2 0 Sigma-70, region 4 DUF977 PF06163.6 EIE84458.1 - 0.12 12.0 0.6 4.9 6.9 0.0 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF977) HTH_17 PF12728.2 EIE84458.1 - 0.13 12.5 0.1 6.1 7.1 0.0 3.1 3 0 0 3 3 2 0 Helix-turn-helix domain DUF1759 PF03564.10 EIE84462.1 - 0.0024 17.6 0.7 0.0038 17.0 0.4 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1759) Gag_p30 PF02093.11 EIE84462.1 - 0.06 12.5 0.2 0.13 11.4 0.0 1.7 2 0 0 2 2 2 0 Gag P30 core shell protein Exo_endo_phos_2 PF14529.1 EIE84463.1 - 5.2e-13 48.6 0.0 1e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase DinB_2 PF12867.2 EIE84463.1 - 0.013 15.8 0.2 0.036 14.3 0.1 1.7 2 0 0 2 2 2 0 DinB superfamily HALZ PF02183.13 EIE84464.1 - 0.00069 19.2 1.0 0.0015 18.1 0.4 1.8 1 1 0 1 1 1 1 Homeobox associated leucine zipper TPR_MLP1_2 PF07926.7 EIE84464.1 - 0.00073 19.2 0.7 0.0011 18.7 0.5 1.2 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.7 EIE84464.1 - 0.0026 16.9 4.4 0.0037 16.4 3.0 1.2 1 0 0 1 1 1 1 Reovirus sigma C capsid protein CCDC155 PF14662.1 EIE84464.1 - 0.0068 16.0 1.2 0.01 15.4 0.8 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 ADIP PF11559.3 EIE84464.1 - 0.0076 16.1 2.1 0.015 15.2 1.4 1.5 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding DUF904 PF06005.7 EIE84464.1 - 0.0093 16.2 2.3 0.019 15.2 1.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF904) DUF972 PF06156.8 EIE84464.1 - 0.022 15.0 0.4 0.041 14.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Phage_GP20 PF06810.6 EIE84464.1 - 0.039 13.4 0.7 0.063 12.7 0.5 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 GAS PF13851.1 EIE84464.1 - 0.048 12.8 1.3 0.073 12.2 0.9 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DivIC PF04977.10 EIE84464.1 - 0.052 13.0 1.3 0.1 12.0 0.5 1.7 1 1 0 1 1 1 0 Septum formation initiator Baculo_PEP_C PF04513.7 EIE84464.1 - 0.072 12.9 7.5 0.12 12.1 5.2 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF869 PF05911.6 EIE84464.1 - 0.093 10.9 2.7 0.14 10.3 1.9 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) DUF2205 PF10224.4 EIE84464.1 - 0.21 11.2 1.7 0.36 10.4 1.2 1.3 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) bZIP_2 PF07716.10 EIE84464.1 - 0.22 11.3 3.3 3.7 7.4 0.1 2.5 1 1 1 2 2 2 0 Basic region leucine zipper DivIVA PF05103.8 EIE84464.1 - 0.22 11.5 2.0 0.31 11.0 0.1 2.0 1 1 1 2 2 2 0 DivIVA protein DUF342 PF03961.8 EIE84464.1 - 0.23 9.8 0.3 0.32 9.3 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) RVT_1 PF00078.22 EIE84465.1 - 1.7e-22 79.8 0.9 1.7e-22 79.8 0.6 2.3 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EIE84465.1 - 1.2e-19 70.5 0.0 2.9e-19 69.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.12 EIE84465.1 - 5.3e-18 64.8 1.5 2.1e-17 62.9 0.4 2.6 2 0 0 2 2 2 1 Retrotransposon gag protein Asp_protease_2 PF13650.1 EIE84465.1 - 3.7e-06 27.3 0.0 7.6e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EIE84465.1 - 2.3e-05 24.1 0.0 4.4e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 EIE84465.1 - 0.00021 21.1 0.0 0.00061 19.6 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.6 EIE84465.1 - 0.00038 20.4 0.0 0.00084 19.2 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 EIE84465.1 - 0.038 13.5 0.0 0.099 12.2 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC PF00098.18 EIE84465.1 - 0.073 13.0 0.6 0.17 11.8 0.4 1.7 1 0 0 1 1 1 0 Zinc knuckle rve PF00665.21 EIE84467.1 - 9.1e-14 51.6 0.0 1.2e-13 51.2 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain DDE_3 PF13358.1 EIE84468.1 - 4.9e-18 65.2 0.0 1.3e-17 63.9 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE84468.1 - 4.1e-07 29.9 1.0 1e-06 28.6 0.6 1.8 1 1 0 1 1 1 1 Transposase DUF2847 PF11009.3 EIE84469.1 - 0.069 12.7 0.1 0.069 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) FlgM PF04316.8 EIE84472.1 - 1.3 9.0 4.0 3.1 7.8 2.8 1.6 1 0 0 1 1 1 0 Anti-sigma-28 factor, FlgM PHD_3 PF13922.1 EIE84472.1 - 7.8 6.8 6.1 37 4.6 3.3 2.1 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx 3HCDH_N PF02737.13 EIE84473.1 - 0.085 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1203 PF06718.6 EIE84474.1 - 0.054 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1203) Transposase_21 PF02992.9 EIE84475.1 - 8.8e-21 74.0 0.0 8.8e-21 74.0 0.0 1.7 2 0 0 2 2 2 1 Transposase family tnp2 DUF1258 PF06869.7 EIE84475.1 - 0.0044 16.1 0.0 0.0091 15.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) DUF2847 PF11009.3 EIE84478.1 - 0.069 12.7 0.1 0.069 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) Transposase_21 PF02992.9 EIE84482.1 - 6.4e-14 51.5 1.1 1.4e-13 50.5 0.1 1.9 2 0 0 2 2 2 1 Transposase family tnp2 DUF1508 PF07411.7 EIE84482.1 - 1.1 8.7 3.5 0.83 9.1 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1508) DDE_3 PF13358.1 EIE84483.1 - 6.4e-18 64.9 0.1 1.1e-17 64.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE84483.1 - 3.3e-09 36.6 0.9 1.3e-08 34.7 0.5 2.0 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.1 EIE84484.1 - 2.6e-13 49.9 0.0 4.9e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE84484.1 - 4.4e-10 39.4 1.1 1.1e-09 38.2 0.8 1.7 1 0 0 1 1 1 1 Transposase HTH_Tnp_4 PF13613.1 EIE84484.1 - 0.0041 16.6 0.0 0.0086 15.5 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease FAM70 PF14967.1 EIE84484.1 - 0.06 12.5 0.0 0.089 11.9 0.0 1.2 1 0 0 1 1 1 0 FAM70 protein HTH_23 PF13384.1 EIE84484.1 - 0.07 12.7 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 Homeodomain-like domain DDE_Tnp_IS1595 PF12762.2 EIE84485.1 - 1.3e-06 28.2 0.1 2.4e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 ISXO2-like transposase domain DDE_Tnp_IS1595 PF12762.2 EIE84486.1 - 2.3e-07 30.7 0.1 4.4e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 ISXO2-like transposase domain NurA PF09376.5 EIE84487.1 - 0.035 13.5 0.4 0.041 13.3 0.3 1.2 1 0 0 1 1 1 0 NurA domain DUF4119 PF13494.1 EIE84487.1 - 0.095 12.6 2.5 0.16 11.9 0.8 2.0 1 1 1 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF4119) PRKCSH PF07915.8 EIE84487.1 - 6.6 7.6 8.9 0.57 11.0 0.8 2.4 1 1 1 2 2 2 0 Glucosidase II beta subunit-like protein RVT_1 PF00078.22 EIE84488.1 - 9.1e-08 31.7 0.0 2.9e-07 30.0 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Spuma_A9PTase PF03539.9 EIE84488.1 - 0.0036 17.2 0.1 0.013 15.4 0.0 1.9 1 1 0 1 1 1 1 Spumavirus aspartic protease (A9) DDE_3 PF13358.1 EIE84489.1 - 5.4e-19 68.3 0.3 3.1e-18 65.9 0.0 2.3 3 0 0 3 3 3 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE84489.1 - 1.1e-11 44.6 0.9 2.5e-11 43.4 0.7 1.7 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.1 EIE84489.1 - 0.0048 17.6 0.2 0.51 11.1 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_29 PF13551.1 EIE84489.1 - 0.0067 16.5 0.0 0.018 15.1 0.0 1.8 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EIE84489.1 - 0.018 14.7 0.1 0.098 12.3 0.0 2.4 3 0 0 3 3 3 0 Homeodomain-like domain Leader_Erm PF08253.6 EIE84490.1 - 1.4 8.4 4.0 0.56 9.7 0.5 2.1 2 0 0 2 2 2 0 Erm Leader peptide Retrotrans_gag PF03732.12 EIE84491.1 - 6.4e-05 22.9 0.0 0.00015 21.8 0.0 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein rve PF00665.21 EIE84492.1 - 1.1e-18 67.4 0.0 2.5e-18 66.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE84492.1 - 3.9e-16 59.0 0.6 8.4e-16 57.9 0.1 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE84492.1 - 1.7e-13 50.0 1.8 4.4e-13 48.6 1.3 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain HTH_Tnp_Tc3_2 PF01498.13 EIE84493.1 - 5.9e-08 32.6 0.4 1.3e-07 31.6 0.3 1.5 1 0 0 1 1 1 1 Transposase zf-DNL PF05180.7 EIE84494.1 - 0.14 11.9 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 DNL zinc finger PIF1 PF05970.9 EIE84495.1 - 8.4e-45 153.2 0.0 1e-44 152.9 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase PIF1 PF05970.9 EIE84496.1 - 9.4e-16 57.7 0.2 1.2e-15 57.3 0.1 1.1 1 0 0 1 1 1 1 PIF1-like helicase Herpes_Helicase PF02689.9 EIE84496.1 - 2.3e-06 25.7 0.0 2.6e-06 25.5 0.0 1.0 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.1 EIE84496.1 - 0.0033 17.5 0.0 0.0055 16.8 0.0 1.5 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain DUF3251 PF11622.3 EIE84496.1 - 0.093 12.1 0.0 0.28 10.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3251) PEX11 PF05648.9 EIE84497.1 - 1.7e-42 145.1 1.8 7.2e-27 94.1 0.3 2.0 1 1 1 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) UCH PF00443.24 EIE84498.1 - 8.4e-74 248.0 0.0 1.8e-73 246.9 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EIE84498.1 - 2.4e-28 99.4 0.0 4.1e-28 98.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.15 EIE84498.1 - 0.0021 18.3 0.1 0.0083 16.4 0.0 2.0 2 0 0 2 2 2 1 Rhodanese-like domain USP8_dimer PF08969.6 EIE84498.1 - 0.016 15.1 0.1 0.029 14.3 0.1 1.4 1 0 0 1 1 1 0 USP8 dimerisation domain zf-4CXXC_R1 PF10497.4 EIE84498.1 - 0.059 13.5 0.3 0.12 12.5 0.2 1.5 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 HhH-GPD PF00730.20 EIE84499.1 - 4.7e-17 62.2 0.0 6e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein DUF4473 PF14747.1 EIE84499.1 - 0.0087 16.2 0.0 0.016 15.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4473) Usp PF00582.21 EIE84502.1 - 1.9e-05 24.8 0.0 2.1e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family DUF4165 PF13752.1 EIE84502.1 - 0.045 13.5 0.0 0.43 10.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4165) 3HCDH PF00725.17 EIE84502.1 - 0.1 12.9 0.0 0.13 12.7 0.0 1.1 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain DUF4238 PF14022.1 EIE84505.1 - 0.1 11.8 0.1 0.17 11.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4238) SPRY PF00622.23 EIE84506.1 - 3.7e-21 75.4 0.3 6e-21 74.8 0.2 1.3 1 0 0 1 1 1 1 SPRY domain Candida_ALS_N PF11766.3 EIE84506.1 - 0.053 12.4 0.0 0.078 11.8 0.0 1.2 1 0 0 1 1 1 0 Cell-wall agglutinin N-terminal ligand-sugar binding SH3_2 PF07653.12 EIE84506.1 - 0.089 12.3 0.2 0.33 10.4 0.0 2.0 2 0 0 2 2 2 0 Variant SH3 domain TGF_beta_GS PF08515.7 EIE84509.1 - 0.053 12.8 1.1 0.092 12.0 0.8 1.4 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif AMP-binding PF00501.23 EIE84510.1 - 2.5e-45 154.6 0.0 3.9e-45 153.9 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EIE84510.1 - 5.1e-37 127.1 0.0 4.3e-36 124.1 0.0 2.3 3 0 0 3 3 3 1 Male sterility protein PP-binding PF00550.20 EIE84510.1 - 2.9e-09 37.0 0.0 5.5e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site TetR_C_8 PF14278.1 EIE84510.1 - 8.2 6.8 9.4 81 3.7 0.0 5.1 5 0 0 5 5 5 0 Transcriptional regulator C-terminal region Glycos_transf_3 PF00591.16 EIE84512.1 - 7.5e-88 294.1 1.1 9.3e-88 293.8 0.8 1.1 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 EIE84512.1 - 2.3e-05 23.8 0.0 5.9e-05 22.5 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain OrfB_Zn_ribbon PF07282.6 EIE84513.1 - 0.00093 18.8 0.4 0.0077 15.8 0.1 2.4 2 0 0 2 2 2 1 Putative transposase DNA-binding domain BIR PF00653.16 EIE84513.1 - 0.065 13.6 0.0 0.16 12.4 0.0 1.7 1 0 0 1 1 1 0 Inhibitor of Apoptosis domain zf-CCHC PF00098.18 EIE84515.1 - 5.4e-06 26.0 13.6 0.001 18.9 0.2 2.3 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 EIE84515.1 - 0.0055 16.3 7.6 0.067 12.8 0.4 2.4 2 0 0 2 2 2 2 Zinc knuckle RLL PF10036.4 EIE84515.1 - 0.15 11.5 1.4 0.22 10.8 0.9 1.2 1 0 0 1 1 1 0 Putative carnitine deficiency-associated protein Neugrin PF06413.6 EIE84515.1 - 2.2 8.0 5.0 6.5 6.5 3.5 1.8 1 1 0 1 1 1 0 Neugrin RVT_1 PF00078.22 EIE84519.1 - 1.2e-19 70.4 0.1 2.9e-19 69.2 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_3 PF13358.1 EIE84520.1 - 0.00062 19.5 0.0 0.001 18.8 0.0 1.3 2 0 0 2 2 2 1 DDE superfamily endonuclease ATP_transf PF09830.4 EIE84521.1 - 0.059 13.1 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 ATP adenylyltransferase NTP_transferase PF00483.18 EIE84524.1 - 3e-51 174.1 0.0 4.3e-51 173.6 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 EIE84524.1 - 5.9e-11 41.3 6.8 1e-08 34.2 3.2 3.3 1 1 2 3 3 3 1 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EIE84524.1 - 3.7e-10 40.1 0.0 5.2e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 EIE84524.1 - 0.00058 19.3 6.2 0.00058 19.3 4.3 2.7 2 1 1 3 3 3 1 Hexapeptide repeat of succinyl-transferase DUF2080 PF09853.4 EIE84524.1 - 0.028 14.1 0.0 0.91 9.3 0.0 2.8 3 0 0 3 3 3 0 Putative transposon-encoded protein (DUF2080) DUF2810 PF10928.3 EIE84524.1 - 0.038 13.7 0.1 0.094 12.4 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2810) CTP_transf_3 PF02348.14 EIE84524.1 - 0.053 13.1 0.1 0.13 11.8 0.0 1.7 2 0 0 2 2 2 0 Cytidylyltransferase SF3a60_bindingd PF12108.3 EIE84524.1 - 0.06 12.8 0.2 0.13 11.8 0.1 1.6 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain SRP54 PF00448.17 EIE84524.1 - 0.082 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Med13_N PF11597.3 EIE84526.1 - 0.018 13.7 0.3 0.02 13.6 0.2 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 N-terminal DnaB_2 PF07261.6 EIE84526.1 - 0.067 12.8 0.8 0.12 11.9 0.3 1.6 1 1 1 2 2 2 0 Replication initiation and membrane attachment DUF148 PF02520.12 EIE84526.1 - 0.1 12.3 4.3 0.23 11.2 2.7 1.8 1 1 1 2 2 2 0 Domain of unknown function DUF148 DUF2508 PF10704.4 EIE84526.1 - 0.13 12.4 2.1 0.27 11.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) DUF1002 PF06207.6 EIE84526.1 - 0.41 9.9 7.4 0.23 10.7 2.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1002) Dzip-like_N PF13815.1 EIE84526.1 - 5.3 6.8 7.2 0.32 10.8 1.0 1.9 3 0 0 3 3 3 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal Nucleoplasmin PF03066.10 EIE84528.1 - 0.0038 16.7 7.5 0.0064 16.0 5.2 1.3 1 0 0 1 1 1 1 Nucleoplasmin Sigma70_ner PF04546.8 EIE84528.1 - 0.0059 16.2 3.6 0.011 15.3 2.5 1.4 1 0 0 1 1 1 1 Sigma-70, non-essential region Nro1 PF12753.2 EIE84528.1 - 0.036 13.0 1.0 0.052 12.5 0.7 1.2 1 0 0 1 1 1 0 Nuclear pore complex subunit Nro1 Nop14 PF04147.7 EIE84528.1 - 0.038 11.9 3.3 0.057 11.3 2.3 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 EIE84528.1 - 0.052 11.5 0.6 0.06 11.3 0.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Sporozoite_P67 PF05642.6 EIE84528.1 - 0.12 10.2 0.7 0.16 9.8 0.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen BTV_NS2 PF04514.7 EIE84528.1 - 0.12 11.2 1.8 0.23 10.2 1.3 1.4 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF4611 PF15387.1 EIE84528.1 - 0.12 12.5 4.8 0.32 11.1 3.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Bd3614_N PF14442.1 EIE84528.1 - 0.13 12.2 2.3 0.22 11.4 1.6 1.3 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal RXT2_N PF08595.6 EIE84528.1 - 0.14 12.0 5.0 0.069 12.9 1.7 1.8 2 0 0 2 2 2 0 RXT2-like, N-terminal BUD22 PF09073.5 EIE84528.1 - 0.15 11.1 6.3 0.2 10.6 4.4 1.2 1 0 0 1 1 1 0 BUD22 FAM176 PF14851.1 EIE84528.1 - 0.45 10.1 3.3 0.96 9.1 2.3 1.5 1 0 0 1 1 1 0 FAM176 family NOA36 PF06524.7 EIE84528.1 - 0.85 8.8 5.7 1.2 8.2 4.0 1.2 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.5 EIE84528.1 - 1.4 9.1 13.9 3 8.1 9.7 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Senescence_reg PF04520.8 EIE84528.1 - 2.2 8.7 8.4 0.4 11.1 2.0 2.4 2 1 1 3 3 3 0 Senescence regulator ERM PF00769.14 EIE84529.1 - 0.0049 16.4 6.4 0.0074 15.8 4.5 1.4 1 1 0 1 1 1 1 Ezrin/radixin/moesin family DUF1351 PF07083.6 EIE84529.1 - 0.072 12.7 4.0 0.57 9.7 2.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1351) IncA PF04156.9 EIE84529.1 - 0.073 12.6 9.0 0.083 12.4 6.2 1.2 1 0 0 1 1 1 0 IncA protein Spectrin PF00435.16 EIE84529.1 - 0.074 13.3 4.4 0.082 13.2 2.7 1.4 1 1 0 1 1 1 0 Spectrin repeat Spc7 PF08317.6 EIE84530.1 - 3.3e-34 118.0 23.8 3.3e-34 118.0 16.5 2.6 2 1 1 3 3 3 1 Spc7 kinetochore protein DDE_3 PF13358.1 EIE84531.1 - 4e-33 114.2 0.0 6.3e-33 113.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.14 EIE84531.1 - 0.00031 19.9 0.0 0.00076 18.6 0.0 1.6 1 1 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE84531.1 - 0.015 15.3 0.0 0.029 14.4 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain Gag_spuma PF03276.9 EIE84532.1 - 0.0015 16.9 8.3 0.002 16.5 5.7 1.0 1 0 0 1 1 1 1 Spumavirus gag protein DivIC PF04977.10 EIE84532.1 - 0.0019 17.6 0.2 0.003 17.0 0.1 1.3 1 0 0 1 1 1 1 Septum formation initiator TMF_DNA_bd PF12329.3 EIE84532.1 - 0.021 14.5 0.4 0.035 13.9 0.3 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Rab5-bind PF09311.6 EIE84532.1 - 0.03 14.2 0.2 0.048 13.5 0.1 1.3 1 0 0 1 1 1 0 Rabaptin-like protein SlyX PF04102.7 EIE84532.1 - 0.066 13.5 0.4 0.066 13.5 0.3 1.8 2 0 0 2 2 2 0 SlyX Ino80_Iec3 PF14612.1 EIE84532.1 - 0.09 12.8 0.1 0.28 11.2 0.0 1.7 2 0 0 2 2 2 0 IEC3 subunit of the Ino80 complex, chromatin re-modelling MCPVI PF02993.9 EIE84532.1 - 4.8 7.2 6.5 5.9 6.9 4.5 1.1 1 0 0 1 1 1 0 Minor capsid protein VI TIP41 PF04176.8 EIE84533.1 - 2.8e-66 222.2 0.3 3.9e-66 221.7 0.2 1.2 1 0 0 1 1 1 1 TIP41-like family AMP-binding PF00501.23 EIE84534.1 - 2.2e-37 128.4 0.0 3.9e-37 127.6 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EIE84534.1 - 3.8e-37 127.5 0.0 3e-36 124.6 0.0 2.3 3 0 0 3 3 3 1 Male sterility protein PP-binding PF00550.20 EIE84534.1 - 2.9e-09 37.0 0.0 5.4e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site WD40 PF00400.27 EIE84535.1 - 1.1e-41 139.2 7.0 2e-09 36.9 0.0 6.6 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 EIE84535.1 - 3.9e-10 39.7 0.0 3.5e-06 26.8 0.0 2.6 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 EIE84535.1 - 0.0026 17.2 0.1 0.02 14.3 0.1 2.1 1 1 0 1 1 1 1 PQQ-like domain DUF3312 PF11768.3 EIE84535.1 - 0.075 11.2 0.0 2.9 5.9 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3312) PQQ_3 PF13570.1 EIE84535.1 - 0.084 13.1 0.1 13 6.2 0.0 3.7 4 0 0 4 4 4 0 PQQ-like domain HEAT PF02985.17 EIE84536.1 - 1.1e-39 130.9 20.0 0.0002 21.1 0.0 12.7 13 0 0 13 13 13 8 HEAT repeat HEAT_2 PF13646.1 EIE84536.1 - 1.1e-29 102.5 0.2 3.4e-05 24.0 0.1 6.0 2 1 5 7 7 7 7 HEAT repeats HEAT_EZ PF13513.1 EIE84536.1 - 1.1e-16 60.7 10.8 0.0058 17.0 0.0 8.3 8 1 1 9 9 9 5 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EIE84536.1 - 4.2e-13 49.4 1.0 0.00018 21.8 0.0 6.5 4 2 4 8 8 8 2 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 EIE84536.1 - 3.3e-06 25.7 7.7 0.08 11.2 0.0 4.0 3 2 3 6 6 6 3 Adaptin N terminal region CLASP_N PF12348.3 EIE84536.1 - 2.8e-05 23.6 0.9 0.6 9.4 0.0 4.8 2 1 2 4 4 4 1 CLASP N terminal Arm PF00514.18 EIE84536.1 - 6.8e-05 22.5 4.4 0.54 10.1 0.0 5.8 7 0 0 7 7 7 1 Armadillo/beta-catenin-like repeat Cnd1 PF12717.2 EIE84536.1 - 0.00063 19.6 6.2 0.089 12.6 0.0 4.9 4 2 2 6 6 6 1 non-SMC mitotic condensation complex subunit 1 DUF2435 PF10363.4 EIE84536.1 - 0.00063 19.5 7.0 1.5 8.7 0.2 5.4 3 2 5 8 8 8 1 Protein of unknown function (DUF2435) Aa_trans PF01490.13 EIE84537.1 - 7.1e-71 238.8 26.9 2.6e-70 236.9 18.7 1.7 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2304 PF10066.4 EIE84537.1 - 2.7 7.8 13.6 0.041 13.7 0.7 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) DUF3158 PF11358.3 EIE84538.1 - 0.033 13.6 0.7 0.1 12.0 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3158) zf-C2H2_jaz PF12171.3 EIE84539.1 - 7.7e-05 22.7 3.7 0.15 12.2 0.1 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EIE84539.1 - 0.0032 17.6 2.0 0.012 15.7 0.2 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 EIE84539.1 - 0.029 14.6 0.3 0.029 14.6 0.2 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIE84539.1 - 0.034 14.4 6.1 0.34 11.3 0.2 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EIE84539.1 - 0.12 12.2 0.3 0.12 12.2 0.2 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger DDE_3 PF13358.1 EIE84540.1 - 2.6e-25 88.8 0.0 4.9e-25 87.9 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 EIE84540.1 - 0.00027 21.0 0.0 0.00052 20.1 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.1 EIE84540.1 - 0.0049 16.8 0.3 0.013 15.5 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain RVT_1 PF00078.22 EIE84541.1 - 1.7e-33 115.7 0.0 3.7e-33 114.7 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TraY PF05509.6 EIE84541.1 - 0.11 12.2 0.1 0.84 9.4 0.0 2.2 2 0 0 2 2 2 0 TraY domain Malic_M PF03949.10 EIE84542.1 - 2.2e-82 276.4 0.0 3.4e-82 275.8 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 EIE84542.1 - 3.1e-72 241.9 0.0 5.3e-72 241.2 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain ubiquitin PF00240.18 EIE84543.1 - 2e-16 59.1 0.0 3.4e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EIE84543.1 - 0.00011 21.8 0.2 0.00021 20.8 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EIE84543.1 - 0.00026 21.1 0.6 0.00056 20.0 0.1 1.9 2 1 0 2 2 2 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 EIE84543.1 - 0.0049 16.7 0.0 0.012 15.4 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Fungal_trans PF04082.13 EIE84544.1 - 5.1e-42 143.5 0.2 5.1e-42 143.5 0.1 2.2 3 0 0 3 3 3 1 Fungal specific transcription factor domain DUF3395 PF11875.3 EIE84544.1 - 0.2 11.3 1.2 5.8 6.5 0.9 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3395) Cyclin PF08613.6 EIE84545.1 - 1.7e-16 60.9 1.5 3e-16 60.1 1.0 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EIE84545.1 - 0.0035 16.9 0.4 0.023 14.2 0.0 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain Imm9 PF15561.1 EIE84545.1 - 0.059 12.9 0.3 0.11 12.1 0.2 1.4 1 0 0 1 1 1 0 Immunity protein 9 RNA_pol_N PF01194.12 EIE84545.1 - 0.11 12.5 0.1 0.28 11.2 0.1 1.7 1 0 0 1 1 1 0 RNA polymerases N / 8 kDa subunit Aminotran_1_2 PF00155.16 EIE84546.1 - 1.2e-84 284.4 0.0 1.3e-84 284.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Thaumatin PF00314.12 EIE84547.1 - 2.5e-54 183.9 9.8 3.3e-54 183.5 6.8 1.1 1 0 0 1 1 1 1 Thaumatin family MHC2-interact PF09307.5 EIE84551.1 - 0.015 15.0 0.7 0.018 14.8 0.5 1.2 1 0 0 1 1 1 0 CLIP, MHC2 interacting CENP-F_leu_zip PF10473.4 EIE84551.1 - 0.037 13.8 0.2 0.052 13.3 0.1 1.1 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Baculo_p24 PF05073.7 EIE84551.1 - 0.065 12.8 0.1 0.076 12.5 0.1 1.1 1 0 0 1 1 1 0 Baculovirus P24 capsid protein Ribosomal_L19e PF01280.15 EIE84552.1 - 1.1e-21 77.1 4.1 1.1e-21 77.1 2.8 1.7 2 0 0 2 2 2 1 Ribosomal protein L19e Sigma54_DBD PF04552.8 EIE84552.1 - 0.057 12.9 3.3 0.77 9.2 0.1 2.1 2 0 0 2 2 2 0 Sigma-54, DNA binding domain DUF4602 PF15375.1 EIE84552.1 - 0.12 12.4 8.7 0.12 12.3 6.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4602) OmdA PF13376.1 EIE84552.1 - 0.18 11.4 0.4 0.18 11.4 0.3 2.4 2 1 1 3 3 3 0 Bacteriocin-protection, YdeI or OmpD-Associated CAF-1_p150 PF11600.3 EIE84553.1 - 1.2 8.5 66.5 1.8 7.8 46.1 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Ribosomal_S2 PF00318.15 EIE84554.1 - 4.8e-43 146.8 0.2 6.2e-21 74.6 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 Ribosomal_L27e PF01777.13 EIE84555.1 - 2.9e-37 126.6 7.1 4.4e-37 126.0 4.9 1.3 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 EIE84555.1 - 8e-05 22.2 1.8 8e-05 22.2 1.3 1.9 2 0 0 2 2 2 1 KOW motif Cyclase_polyket PF04673.7 EIE84556.1 - 0.028 14.4 0.1 0.057 13.4 0.0 1.6 1 1 0 1 1 1 0 Polyketide synthesis cyclase PASTA PF03793.14 EIE84556.1 - 0.035 13.7 0.1 0.11 12.2 0.0 1.9 2 0 0 2 2 2 0 PASTA domain DUF4463 PF14703.1 EIE84556.1 - 0.064 13.7 0.2 0.11 13.0 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4463) LEM PF03020.10 EIE84556.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 LEM domain SAP PF02037.22 EIE84556.1 - 0.13 11.8 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 SAP domain Apc13p PF05839.6 EIE84556.1 - 0.15 12.0 2.4 0.98 9.4 0.1 2.7 2 1 0 2 2 2 0 Apc13p protein Lon_C PF05362.8 EIE84557.1 - 2e-72 242.8 0.4 4.1e-72 241.7 0.3 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 EIE84557.1 - 6.8e-27 94.4 1.6 1.6e-26 93.2 0.1 2.4 4 0 0 4 4 4 1 ATP-dependent protease La (LON) domain AAA PF00004.24 EIE84557.1 - 4.7e-23 81.8 0.0 1.1e-22 80.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EIE84557.1 - 2.6e-08 33.6 0.0 3.1e-06 26.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) ChlI PF13541.1 EIE84557.1 - 2.8e-07 30.0 0.1 1.3e-06 27.9 0.0 2.2 2 1 0 2 2 2 1 Subunit ChlI of Mg-chelatase AAA_17 PF13207.1 EIE84557.1 - 6.5e-06 26.9 0.0 2.8e-05 24.9 0.0 2.2 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.1 EIE84557.1 - 0.00015 21.8 0.3 0.024 14.7 0.0 3.2 2 1 0 2 2 2 1 AAA domain AAA_3 PF07726.6 EIE84557.1 - 0.00018 21.1 0.0 0.0004 20.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EIE84557.1 - 0.0002 20.5 0.0 0.00066 18.7 0.0 1.9 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EIE84557.1 - 0.0002 21.4 0.0 0.00063 19.7 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_PrkA PF08298.6 EIE84557.1 - 0.00023 19.9 0.0 0.00043 19.0 0.0 1.3 1 0 0 1 1 1 1 PrkA AAA domain AAA_14 PF13173.1 EIE84557.1 - 0.00051 19.9 0.0 0.0013 18.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EIE84557.1 - 0.0016 17.6 0.0 0.0033 16.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 EIE84557.1 - 0.0027 17.9 0.4 0.009 16.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.9 EIE84557.1 - 0.0042 17.0 0.0 0.017 15.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 EIE84557.1 - 0.0067 15.8 0.1 0.024 14.0 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_33 PF13671.1 EIE84557.1 - 0.016 15.1 0.0 0.035 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EIE84557.1 - 0.052 13.7 0.0 0.13 12.3 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.1 EIE84557.1 - 0.055 13.0 0.2 0.13 11.7 0.1 1.6 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 EIE84557.1 - 0.058 13.0 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B SKI PF01202.17 EIE84557.1 - 0.092 12.6 1.1 0.21 11.4 0.0 2.1 2 0 0 2 2 2 0 Shikimate kinase AAA_23 PF13476.1 EIE84557.1 - 0.4 10.9 0.0 0.4 10.9 0.0 2.8 1 1 1 2 2 1 0 AAA domain LRR_4 PF12799.2 EIE84558.1 - 3.5e-15 55.2 15.9 4.1e-08 32.6 2.3 3.5 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EIE84558.1 - 1.2e-10 41.0 12.6 2.2e-07 30.4 3.0 2.8 1 1 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 EIE84558.1 - 8.9e-09 34.1 13.2 0.0039 17.0 0.6 5.0 4 0 0 4 4 4 3 Leucine Rich Repeat LRR_7 PF13504.1 EIE84558.1 - 0.00025 20.7 9.9 0.22 11.8 0.1 5.1 4 0 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.1 EIE84558.1 - 0.082 13.0 6.6 49 4.4 0.1 4.6 4 0 0 4 4 4 0 Leucine Rich repeat Acetyltransf_3 PF13302.1 EIE84558.1 - 0.1 12.7 0.1 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DNA_ligase_OB_2 PF14743.1 EIE84558.1 - 0.11 12.1 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 DNA ligase OB-like domain Peptidase_S10 PF00450.17 EIE84560.1 - 4e-06 26.2 0.1 4.6e-06 26.0 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase IF4E PF01652.13 EIE84561.1 - 1.1e-26 93.3 0.0 2.4e-26 92.2 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DUF2217 PF10265.4 EIE84561.1 - 0.0019 17.0 0.6 0.0019 17.0 0.4 1.6 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2217) Ydc2-catalyt PF09159.5 EIE84562.1 - 6.7e-25 88.1 7.5 1.7e-21 76.9 1.5 3.3 1 1 1 2 2 2 2 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Metallophos PF00149.23 EIE84562.1 - 2.2e-16 59.8 0.3 4.2e-16 58.9 0.2 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EIE84562.1 - 9.7e-13 48.2 0.0 1.9e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Pox_A22 PF04848.8 EIE84562.1 - 0.0029 17.4 0.7 0.048 13.5 0.0 2.7 2 1 0 2 2 2 1 Poxvirus A22 protein SAP PF02037.22 EIE84562.1 - 0.0032 16.9 0.1 0.0071 15.8 0.0 1.6 1 0 0 1 1 1 1 SAP domain Aa_trans PF01490.13 EIE84563.1 - 1.5e-61 208.1 33.0 7.3e-48 163.0 16.4 2.7 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein CAAD PF14159.1 EIE84563.1 - 3.3 7.4 6.0 1.2 8.8 0.4 2.9 3 0 0 3 3 3 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase BCAS2 PF05700.6 EIE84565.1 - 9.4e-55 185.4 17.3 1e-54 185.3 12.0 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) DUF1318 PF07027.7 EIE84565.1 - 0.013 15.6 0.4 0.04 14.1 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1318) IMS_C PF11799.3 EIE84565.1 - 0.021 14.7 0.6 0.036 13.9 0.4 1.5 1 1 0 1 1 1 0 impB/mucB/samB family C-terminal domain VPR PF00522.13 EIE84565.1 - 0.31 10.8 2.6 0.22 11.3 0.3 1.9 2 1 0 2 2 2 0 VPR/VPX protein ARGLU PF15346.1 EIE84565.1 - 1.1 9.0 15.7 0.073 12.8 4.5 2.3 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 FUN14 PF04930.10 EIE84565.1 - 1.2 9.5 6.2 0.51 10.6 0.2 2.5 2 1 0 2 2 2 0 FUN14 family DUF1515 PF07439.6 EIE84565.1 - 2.2 8.1 4.6 0.73 9.6 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) ParB PF08775.5 EIE84565.1 - 3.6 7.9 10.1 2.4 8.4 1.7 2.8 2 1 1 3 3 3 0 ParB family Cas_Cas4 PF01930.12 EIE84565.1 - 4.5 7.1 8.7 20 5.0 6.0 2.0 1 1 0 1 1 1 0 Domain of unknown function DUF83 CotH PF08757.6 EIE84566.1 - 1.6e-38 132.7 7.1 2.9e-38 131.9 4.9 1.4 1 0 0 1 1 1 1 CotH protein CotH PF08757.6 EIE84567.1 - 1.2e-38 133.2 4.8 1.6e-38 132.7 3.3 1.2 1 0 0 1 1 1 1 CotH protein GLTSCR1 PF15249.1 EIE84568.1 - 2e-05 24.6 0.1 2e-05 24.6 0.0 2.9 4 1 0 4 4 4 1 Glioma tumor suppressor candidate region CPSF73-100_C PF11718.3 EIE84568.1 - 6.9 5.9 9.6 1.1 8.6 3.5 1.9 2 0 0 2 2 2 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term HTH_Tnp_Tc3_2 PF01498.13 EIE84569.1 - 1e-07 31.8 0.7 2.1e-07 30.8 0.5 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.1 EIE84569.1 - 1.4e-06 28.0 1.1 3.7e-06 26.7 0.8 1.8 1 1 0 1 1 1 1 DDE superfamily endonuclease ALO PF04030.9 EIE84569.1 - 0.038 13.5 0.2 0.054 13.0 0.1 1.3 1 0 0 1 1 1 0 D-arabinono-1,4-lactone oxidase DUF1543 PF07566.7 EIE84569.1 - 1 8.9 4.8 6.6 6.3 0.0 3.1 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1543) AAA_16 PF13191.1 EIE84571.1 - 3.4e-10 40.2 0.2 4.2e-06 26.8 0.1 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 EIE84571.1 - 0.0019 18.3 0.3 0.047 13.8 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EIE84571.1 - 0.0075 17.0 0.1 0.069 13.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EIE84571.1 - 0.011 14.9 0.0 0.11 11.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 RNA_helicase PF00910.17 EIE84571.1 - 0.015 15.4 0.2 0.055 13.6 0.0 2.1 2 0 0 2 2 1 0 RNA helicase IstB_IS21 PF01695.12 EIE84571.1 - 0.016 14.6 0.0 0.047 13.1 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein NACHT PF05729.7 EIE84571.1 - 0.018 14.6 0.0 3.2 7.3 0.0 2.5 2 0 0 2 2 2 0 NACHT domain Guanylate_cyc PF00211.15 EIE84571.1 - 0.022 14.1 0.0 2.7 7.3 0.0 3.2 3 0 0 3 3 3 0 Adenylate and Guanylate cyclase catalytic domain DUF1572 PF07609.6 EIE84571.1 - 0.033 13.7 0.0 0.088 12.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1572) AAA_25 PF13481.1 EIE84571.1 - 0.048 13.0 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain NPCBM PF08305.6 EIE84571.1 - 0.13 12.2 0.1 0.25 11.2 0.1 1.4 1 0 0 1 1 1 0 NPCBM/NEW2 domain Peptidase_M24 PF00557.19 EIE84572.1 - 2.3e-14 53.4 0.0 2.8e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 PH PF00169.24 EIE84573.1 - 6.2e-10 39.2 4.2 1.3e-08 34.9 0.0 4.1 4 0 0 4 4 4 1 PH domain PH_9 PF15410.1 EIE84573.1 - 0.018 15.2 2.1 0.091 12.9 0.0 3.3 4 0 0 4 4 4 0 Pleckstrin homology domain Peptidase_S10 PF00450.17 EIE84575.1 - 1.3e-125 419.8 0.1 1.7e-125 419.5 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Ank_5 PF13857.1 EIE84577.1 - 3.2e-05 24.0 0.1 7.7e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) zf-CCHC PF00098.18 EIE84579.1 - 0.00019 21.1 8.3 0.0018 18.1 0.3 2.3 2 0 0 2 2 2 2 Zinc knuckle DUF1660 PF07874.6 EIE84579.1 - 0.1 12.8 2.2 0.22 11.8 1.5 1.6 1 0 0 1 1 1 0 Prophage protein (DUF1660) zf-CCHC_4 PF14392.1 EIE84579.1 - 0.49 10.1 6.0 0.59 9.8 0.7 2.2 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_3 PF13917.1 EIE84579.1 - 1.6 8.5 8.5 1.3 8.8 0.4 2.3 1 1 1 2 2 2 0 Zinc knuckle DnaJ PF00226.26 EIE84581.1 - 1.2e-11 44.1 0.2 1.7e-11 43.6 0.1 1.2 1 0 0 1 1 1 1 DnaJ domain UPF0203 PF05254.7 EIE84582.1 - 3e-28 97.4 2.1 3.5e-28 97.2 1.4 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) UCR_hinge PF02320.11 EIE84582.1 - 0.0016 18.3 0.3 0.0023 17.8 0.2 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein CHCH PF06747.8 EIE84582.1 - 0.012 15.5 0.9 0.75 9.7 0.0 2.3 2 0 0 2 2 2 0 CHCH domain COX17 PF05051.8 EIE84582.1 - 0.06 13.3 1.0 0.12 12.4 0.7 1.5 1 1 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.5 EIE84582.1 - 0.29 10.9 4.1 1.5 8.6 0.2 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like COX6B PF02297.12 EIE84582.1 - 0.53 10.3 5.2 4 7.5 0.8 2.1 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb Peptidase_M48 PF01435.13 EIE84584.1 - 2.4e-05 23.9 0.0 4.1e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M48 Pkinase PF00069.20 EIE84585.1 - 3.5e-52 177.1 0.8 6.4e-52 176.2 0.1 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE84585.1 - 7.6e-21 74.3 0.0 1.3e-20 73.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE84585.1 - 0.00048 19.1 0.0 0.00093 18.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EIE84585.1 - 0.0069 16.1 0.0 0.017 14.8 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF3900 PF13039.1 EIE84586.1 - 0.0056 16.2 0.0 0.0067 16.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3900) Calpain_III PF01067.17 EIE84586.1 - 0.14 11.7 0.6 0.19 11.3 0.4 1.3 1 1 0 1 1 1 0 Calpain large subunit, domain III AGTRAP PF06396.6 EIE84587.1 - 2.9e-09 36.7 0.0 3.2e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Angiotensin II, type I receptor-associated protein (AGTRAP) PAM2 PF07145.10 EIE84588.1 - 0.0047 16.3 1.6 0.013 14.9 1.1 1.8 1 0 0 1 1 1 1 Ataxin-2 C-terminal region SID-1_RNA_chan PF13965.1 EIE84588.1 - 2.1 6.4 4.1 2.5 6.1 2.8 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 PH PF00169.24 EIE84590.1 - 3.9e-07 30.2 1.4 5.5e-07 29.7 0.1 1.9 2 1 0 2 2 2 1 PH domain AvrE PF11725.3 EIE84590.1 - 0.43 7.5 31.9 0.55 7.1 22.1 1.2 1 0 0 1 1 1 0 Pathogenicity factor MIP-T3 PF10243.4 EIE84590.1 - 0.75 8.2 70.1 1.1 7.6 48.6 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CAP_GLY PF01302.20 EIE84591.1 - 4.3e-17 61.5 0.1 7.2e-17 60.8 0.0 1.4 1 0 0 1 1 1 1 CAP-Gly domain PNRC PF15365.1 EIE84593.1 - 2.6e-15 56.1 0.2 2.6e-15 56.1 0.1 2.1 2 1 0 2 2 2 1 Proline-rich nuclear receptor coactivator Abi_HHR PF07815.9 EIE84593.1 - 0.076 13.1 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Abl-interactor HHR DUF3432 PF11914.3 EIE84593.1 - 0.16 12.0 3.6 0.28 11.2 2.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3432) SR-25 PF10500.4 EIE84593.1 - 0.23 10.9 7.4 0.28 10.6 5.1 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF2207 PF09972.4 EIE84593.1 - 0.44 9.0 2.5 0.58 8.6 1.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) KH_2 PF07650.12 EIE84594.1 - 1.6e-14 53.1 0.1 2.1e-14 52.8 0.1 1.1 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.3 EIE84594.1 - 0.0021 18.2 0.0 0.0032 17.7 0.0 1.3 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 DUF1875 PF08961.5 EIE84595.1 - 0.057 12.7 0.8 0.063 12.5 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1875) TSC22 PF01166.13 EIE84595.1 - 0.058 13.3 3.7 0.089 12.7 2.6 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family DUF904 PF06005.7 EIE84595.1 - 0.16 12.2 6.9 0.27 11.5 4.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DivIC PF04977.10 EIE84595.1 - 1.5 8.3 6.5 2.2 7.7 4.5 1.3 1 0 0 1 1 1 0 Septum formation initiator MRP-S33 PF08293.6 EIE84596.1 - 9e-29 99.2 0.0 1.1e-28 99.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 RHH_1 PF01402.16 EIE84596.1 - 0.094 12.6 0.7 0.16 11.9 0.5 1.4 1 0 0 1 1 1 0 Ribbon-helix-helix protein, copG family DUF726 PF05277.7 EIE84598.1 - 2.2e-113 378.6 8.1 1.9e-112 375.5 5.6 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_5 PF12695.2 EIE84598.1 - 0.0024 17.6 0.0 0.016 14.9 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIE84598.1 - 0.01 15.3 0.1 0.053 13.0 0.0 2.1 3 0 0 3 3 3 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EIE84598.1 - 0.069 13.0 0.1 0.18 11.6 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family tRNA-synt_1c PF00749.16 EIE84599.1 - 2.8e-107 358.0 0.0 4.2e-107 357.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EIE84599.1 - 1.4e-40 138.8 0.4 1.4e-40 138.8 0.3 2.3 3 0 0 3 3 3 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 EIE84599.1 - 2.7e-08 34.2 0.1 7.1e-08 32.8 0.1 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EIE84599.1 - 0.014 15.3 0.1 0.038 13.9 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.14 EIE84599.1 - 0.017 14.2 0.0 0.028 13.5 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain GST_C_2 PF13410.1 EIE84599.1 - 0.019 14.8 0.0 0.042 13.7 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DnaJ PF00226.26 EIE84600.1 - 2.3e-28 97.6 2.1 3.7e-28 97.0 1.5 1.3 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.1 EIE84600.1 - 0.0073 15.6 0.0 0.018 14.4 0.0 1.6 1 1 1 2 2 2 1 A repeated domain in UCH-protein Ribosom_S12_S23 PF00164.20 EIE84601.1 - 3.9e-40 136.0 0.4 4.6e-40 135.8 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 ADK PF00406.17 EIE84602.1 - 1.7e-46 157.8 0.0 2.6e-46 157.2 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 EIE84602.1 - 1.8e-11 44.4 0.2 4.3e-11 43.2 0.0 1.7 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EIE84602.1 - 3.2e-09 37.6 0.0 5.7e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EIE84602.1 - 3.3e-09 36.7 0.0 1.1e-08 35.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EIE84602.1 - 9.7e-05 21.5 0.0 0.00014 21.0 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin Thymidylate_kin PF02223.12 EIE84602.1 - 0.00017 21.0 2.2 0.17 11.2 0.0 2.7 3 0 0 3 3 3 2 Thymidylate kinase AAA_28 PF13521.1 EIE84602.1 - 0.0052 16.7 0.3 0.016 15.1 0.0 1.9 3 0 0 3 3 3 1 AAA domain Auto_anti-p27 PF06677.7 EIE84605.1 - 1.5e-11 43.8 1.1 1.7e-05 24.4 0.0 2.4 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) LETM1 PF07766.8 EIE84605.1 - 0.28 10.2 7.0 0.45 9.5 4.9 1.3 1 0 0 1 1 1 0 LETM1-like protein Methyltransf_32 PF13679.1 EIE84605.1 - 6.9 6.3 8.7 12 5.6 3.7 2.3 1 1 1 2 2 2 0 Methyltransferase domain V-SNARE PF05008.10 EIE84606.1 - 3.5e-24 84.7 7.2 2.4e-23 82.1 3.2 2.4 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.3 EIE84606.1 - 1.6e-19 69.7 3.6 1.6e-19 69.7 2.5 2.5 2 1 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Ribosomal_S8 PF00410.14 EIE84606.1 - 0.087 12.6 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein S8 DUF2730 PF10805.3 EIE84606.1 - 0.18 11.5 1.6 0.39 10.4 1.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) SNARE PF05739.14 EIE84606.1 - 0.33 10.6 4.1 4.8 6.9 0.0 2.7 2 0 0 2 2 2 0 SNARE domain CENP-F_leu_zip PF10473.4 EIE84606.1 - 0.49 10.2 5.3 1.7 8.4 3.7 2.0 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Nbl1_Borealin_N PF10444.4 EIE84606.1 - 0.79 9.1 4.0 2.7 7.4 0.3 3.0 2 1 1 3 3 3 0 Nbl1 / Borealin N terminal CLASP_N PF12348.3 EIE84607.1 - 1.9e-54 184.4 0.5 3.4e-54 183.6 0.3 1.4 1 0 0 1 1 1 1 CLASP N terminal HEAT PF02985.17 EIE84607.1 - 0.001 18.9 2.6 3.9 7.7 0.0 5.1 6 0 0 6 6 6 2 HEAT repeat TEA PF01285.13 EIE84608.1 - 6.9e-37 127.6 0.1 2.9e-33 115.6 0.0 2.1 2 0 0 2 2 2 2 TEA/ATTS domain family DUF4452 PF14618.1 EIE84608.1 - 0.04 13.7 0.2 0.089 12.6 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4452) Baculo_LEF5 PF04838.7 EIE84608.1 - 0.059 13.1 0.9 0.48 10.1 0.1 2.2 2 0 0 2 2 2 0 Baculoviridae late expression factor 5 PspA_IM30 PF04012.7 EIE84609.1 - 0.0077 15.6 3.1 0.013 14.8 2.2 1.3 1 0 0 1 1 1 1 PspA/IM30 family Pup PF05639.6 EIE84609.1 - 1.6 9.2 5.9 0.43 11.0 0.9 2.3 2 1 0 2 2 2 0 Pup-like protein 5_3_exonuc PF01367.15 EIE84609.1 - 4 7.7 7.8 2 8.7 1.1 3.0 1 1 2 3 3 3 0 5'-3' exonuclease, C-terminal SAM fold DNase_II PF03265.10 EIE84610.1 - 0.098 11.6 0.1 0.11 11.5 0.0 1.0 1 0 0 1 1 1 0 Deoxyribonuclease II MiaE_2 PF13794.1 EIE84611.1 - 0.016 14.7 0.7 0.31 10.5 0.2 2.1 1 1 1 2 2 2 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like DUF3194 PF11419.3 EIE84612.1 - 7.4 6.8 14.4 1.1 9.5 0.8 4.0 1 1 2 4 4 4 0 Protein of unknown function (DUF3194) FHA PF00498.21 EIE84613.1 - 1.5e-14 53.8 0.1 3.1e-14 52.8 0.1 1.6 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 EIE84613.1 - 1.2e-08 34.6 7.9 1.2e-08 34.6 5.5 1.9 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 EIE84613.1 - 5e-05 23.3 2.4 5e-05 23.3 1.7 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EIE84613.1 - 0.00014 21.5 6.4 0.00034 20.2 4.4 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EIE84613.1 - 0.00041 19.9 6.3 0.00041 19.9 4.4 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EIE84613.1 - 0.00068 19.2 3.9 0.0017 17.9 2.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIE84613.1 - 0.0045 16.9 8.9 0.0045 16.9 6.1 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 EIE84613.1 - 0.025 14.2 3.9 0.067 12.8 2.7 1.8 1 0 0 1 1 1 0 PHD-finger zf-Apc11 PF12861.2 EIE84613.1 - 0.069 12.9 0.6 0.18 11.6 0.4 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger PAS_6 PF08348.6 EIE84614.1 - 0.047 13.2 0.1 1.3 8.6 0.0 2.2 2 0 0 2 2 2 0 YheO-like PAS domain PAS_6 PF08348.6 EIE84615.1 - 0.12 11.9 0.1 0.21 11.1 0.0 1.4 1 1 0 1 1 1 0 YheO-like PAS domain Peptidase_M16_C PF05193.16 EIE84617.1 - 3.6e-16 59.3 0.1 6.3e-16 58.5 0.1 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EIE84617.1 - 5.1e-06 26.3 1.1 7.4e-06 25.7 0.2 1.7 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_C41 PF05417.6 EIE84617.1 - 0.22 11.0 2.7 3.1 7.3 0.2 2.9 2 1 1 3 3 3 0 Hepatitis E cysteine protease LSM PF01423.17 EIE84618.1 - 1.7e-16 59.5 0.3 1.7e-16 59.5 0.2 1.6 2 0 0 2 2 2 1 LSM domain FlaC_arch PF05377.6 EIE84618.1 - 0.03 14.2 2.8 0.057 13.3 1.9 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) MAGSP PF03082.9 EIE84618.1 - 0.11 11.8 0.7 0.15 11.4 0.5 1.1 1 0 0 1 1 1 0 Male accessory gland secretory protein Porphobil_deam PF01379.15 EIE84619.1 - 1.3e-80 269.3 0.0 1.7e-80 268.9 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 EIE84619.1 - 1.5e-19 69.8 0.6 3.1e-19 68.8 0.4 1.6 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Dynamin_N PF00350.18 EIE84620.1 - 1.1e-35 122.9 0.0 1.2e-35 122.8 0.0 1.0 1 0 0 1 1 1 1 Dynamin family AAA_16 PF13191.1 EIE84620.1 - 0.0061 16.5 0.1 0.0088 16.0 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain Miro PF08477.8 EIE84620.1 - 0.0078 16.7 0.1 0.012 16.1 0.1 1.5 1 1 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EIE84620.1 - 0.015 15.2 0.1 0.048 13.6 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase Ras PF00071.17 EIE84620.1 - 0.038 13.3 0.0 0.066 12.5 0.0 1.4 1 0 0 1 1 1 0 Ras family AAA_33 PF13671.1 EIE84620.1 - 0.087 12.6 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 EIE84620.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B HTH_28 PF13518.1 EIE84621.1 - 1.5e-06 28.1 0.2 3.4e-06 26.9 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_29 PF13551.1 EIE84621.1 - 5.4e-06 26.5 0.0 7.4e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EIE84621.1 - 6.9e-06 25.5 0.0 1.3e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain CENP-B_N PF04218.8 EIE84621.1 - 0.00025 20.3 0.0 0.018 14.4 0.1 2.4 2 0 0 2 2 2 1 CENP-B N-terminal DNA-binding domain Sigma70_r4_2 PF08281.7 EIE84621.1 - 0.0046 16.3 0.1 0.011 15.1 0.0 1.6 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_38 PF13936.1 EIE84621.1 - 0.0047 16.4 0.2 0.04 13.4 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain Terminase_5 PF06056.7 EIE84621.1 - 0.014 14.9 0.0 0.028 13.9 0.0 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) HTH_17 PF12728.2 EIE84621.1 - 0.014 15.6 0.0 0.058 13.6 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.1 EIE84621.1 - 0.12 12.7 0.1 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 NUMOD1 PF07453.8 EIE84621.1 - 0.15 11.9 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 NUMOD1 domain CTP_transf_1 PF01148.15 EIE84627.1 - 7.8e-75 251.8 24.6 9.6e-75 251.5 17.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family Caveolin PF01146.12 EIE84627.1 - 4.3 6.9 10.0 0.94 9.0 1.0 2.8 2 1 0 2 2 2 0 Caveolin Protocadherin PF08374.6 EIE84628.1 - 0.023 14.3 1.3 0.056 13.0 0.2 2.0 1 1 1 2 2 2 0 Protocadherin Chordopox_L2 PF05803.7 EIE84628.1 - 0.11 12.0 0.1 0.11 12.0 0.1 1.9 2 0 0 2 2 2 0 Chordopoxvirus L2 protein Adeno_E3_CR2 PF02439.10 EIE84628.1 - 0.12 11.9 3.8 0.3 10.6 2.7 1.6 1 1 0 1 1 1 0 Adenovirus E3 region protein CR2 Ribosomal_S8e PF01201.17 EIE84629.1 - 8e-51 171.6 0.7 9.5e-51 171.3 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e Ribosomal_L5_C PF00673.16 EIE84630.1 - 1.7e-23 82.1 0.0 2.4e-23 81.6 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 EIE84630.1 - 1.8e-19 69.2 0.1 5.7e-19 67.6 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L5 FA_desaturase PF00487.19 EIE84631.1 - 9.4e-29 100.6 13.8 1.6e-28 99.8 9.6 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.5 EIE84631.1 - 1.1e-07 30.9 0.7 2.1e-07 30.0 0.5 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Fork_head PF00250.13 EIE84632.1 - 6.7e-33 112.6 0.2 1.3e-32 111.6 0.2 1.5 1 0 0 1 1 1 1 Fork head domain Hormone_5 PF00184.12 EIE84634.1 - 0.1 13.1 0.4 0.17 12.4 0.2 1.3 1 1 0 1 1 1 0 Neurohypophysial hormones, C-terminal Domain CFC PF09443.5 EIE84634.1 - 0.87 9.2 3.6 3.1 7.4 0.1 2.5 3 0 0 3 3 3 0 Cripto_Frl-1_Cryptic (CFC) HLH PF00010.21 EIE84635.1 - 1e-14 53.9 0.9 2.2e-14 52.8 0.6 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Imm49 PF15660.1 EIE84635.1 - 0.089 12.8 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 49 LRR_4 PF12799.2 EIE84636.1 - 3e-22 77.7 21.9 1.6e-07 30.7 0.3 4.0 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EIE84636.1 - 1.6e-18 66.1 15.4 1.3e-10 40.8 1.9 2.5 2 0 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 EIE84636.1 - 3.4e-14 50.7 21.0 0.062 13.3 0.1 6.8 7 0 0 7 7 7 5 Leucine Rich Repeat LRR_7 PF13504.1 EIE84636.1 - 1e-09 36.9 15.6 1.3 9.5 0.0 6.8 6 0 0 6 6 6 6 Leucine rich repeat LRR_6 PF13516.1 EIE84636.1 - 1.2e-07 31.0 14.5 0.079 13.0 0.1 6.4 6 0 0 6 6 6 3 Leucine Rich repeat eIF-5_eIF-2B PF01873.12 EIE84636.1 - 0.053 13.1 0.0 0.088 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain found in IF2B/IF5 CRC_subunit PF08624.5 EIE84638.1 - 4.2e-21 75.3 0.1 7.5e-21 74.5 0.1 1.4 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit PHD PF00628.24 EIE84638.1 - 6.9e-19 67.2 52.3 1.6e-08 34.1 8.2 4.3 4 1 1 5 5 5 3 PHD-finger PHD_2 PF13831.1 EIE84638.1 - 0.09 12.1 34.1 0.051 12.9 2.0 4.9 4 1 0 4 4 4 0 PHD-finger RdRP_3 PF00998.18 EIE84640.1 - 0.031 12.7 0.1 0.032 12.7 0.1 1.1 1 0 0 1 1 1 0 Viral RNA dependent RNA polymerase Vhr1 PF04001.8 EIE84640.1 - 0.046 13.6 0.6 0.068 13.1 0.2 1.4 2 0 0 2 2 2 0 Transcription factor Vhr1 IFT20 PF14931.1 EIE84641.1 - 0.49 10.2 5.1 7 6.5 2.3 2.6 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 FAR1 PF03101.10 EIE84642.1 - 0.0013 19.1 0.1 0.0021 18.5 0.1 1.3 1 0 0 1 1 1 1 FAR1 DNA-binding domain AKAP7_NLS PF10469.4 EIE84642.1 - 0.039 13.6 0.0 0.053 13.2 0.0 1.1 1 0 0 1 1 1 0 AKAP7 2'5' RNA ligase-like domain RhoGEF PF00621.15 EIE84643.1 - 8.6e-19 68.0 2.8 8.6e-19 68.0 2.0 2.4 2 0 0 2 2 2 1 RhoGEF domain KLRAQ PF10205.4 EIE84644.1 - 1.3e-14 54.0 11.3 1.3e-14 54.0 7.8 5.6 4 3 2 6 6 6 1 Predicted coiled-coil domain-containing protein TTKRSYEDQ PF10212.4 EIE84644.1 - 3.2e-10 39.5 16.8 3.2e-10 39.5 11.6 3.0 1 1 1 3 3 3 1 Predicted coiled-coil domain-containing protein DUF4407 PF14362.1 EIE84644.1 - 0.0043 16.0 12.3 0.0043 16.0 8.5 4.6 2 2 2 4 4 4 2 Domain of unknown function (DUF4407) ATG16 PF08614.6 EIE84644.1 - 0.0047 16.7 18.8 0.0047 16.7 13.0 5.5 2 1 1 4 4 4 2 Autophagy protein 16 (ATG16) Methyltransf_31 PF13847.1 EIE84645.1 - 1.1e-06 28.2 0.0 2.3e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIE84645.1 - 4.2e-06 27.3 0.0 9.3e-06 26.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIE84645.1 - 1.5e-05 24.7 0.0 2.4e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EIE84645.1 - 0.00015 20.9 0.0 0.00033 19.7 0.0 1.4 1 1 0 1 1 1 1 Putative methyltransferase FtsJ PF01728.14 EIE84645.1 - 0.00019 21.4 0.0 0.00027 20.9 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_12 PF08242.7 EIE84645.1 - 0.00062 20.1 0.0 0.0037 17.7 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIE84645.1 - 0.0011 19.3 0.0 0.0028 17.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIE84645.1 - 0.0016 18.8 0.0 0.031 14.7 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.6 EIE84645.1 - 0.0022 16.7 0.0 0.0033 16.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.9 EIE84645.1 - 0.0023 17.3 0.0 0.0038 16.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 EIE84645.1 - 0.0037 16.3 0.0 0.006 15.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MetW PF07021.7 EIE84645.1 - 0.014 14.7 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_2 PF00891.13 EIE84645.1 - 0.028 13.6 0.0 0.052 12.7 0.0 1.3 1 1 0 1 1 1 0 O-methyltransferase PCMT PF01135.14 EIE84645.1 - 0.095 12.2 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.13 EIE84645.1 - 0.11 11.5 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EIE84645.1 - 0.12 12.4 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Glyco_hydro_15 PF00723.16 EIE84646.1 - 1.6e-45 155.5 0.0 3.4e-43 147.8 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 DUF3909 PF13077.1 EIE84646.1 - 0.05 13.4 0.1 0.12 12.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3909) FAA_hydrolase PF01557.13 EIE84647.1 - 5.6e-51 173.0 0.0 6.9e-51 172.7 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 EIE84647.1 - 7.9e-12 45.1 0.0 4.8e-11 42.5 0.1 2.0 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal SART-1 PF03343.8 EIE84649.1 - 1.8e-119 399.9 84.0 2e-119 399.6 58.2 1.0 1 0 0 1 1 1 1 SART-1 family UPF0081 PF03652.10 EIE84649.1 - 0.031 14.3 0.8 0.031 14.3 0.5 3.1 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0081) DUF3866 PF12982.2 EIE84649.1 - 0.18 10.7 2.5 0.5 9.2 1.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3866) RhoGEF PF00621.15 EIE84650.1 - 8.6e-15 55.0 6.6 2.1e-14 53.8 4.6 1.7 1 0 0 1 1 1 1 RhoGEF domain Exo_endo_phos_2 PF14529.1 EIE84652.1 - 0.00075 19.1 0.0 0.002 17.7 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase DUF4263 PF14082.1 EIE84652.1 - 0.0083 16.0 0.4 0.078 12.9 0.2 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF4263) KIF1B PF12423.3 EIE84652.1 - 0.035 14.1 0.1 0.35 10.9 0.0 2.2 2 0 0 2 2 2 0 Kinesin protein 1B DUF445 PF04286.7 EIE84652.1 - 0.18 11.2 1.1 1.4 8.3 0.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF445) DUF3573 PF12097.3 EIE84653.1 - 0.011 14.3 1.8 0.014 14.0 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DUF4613 PF15390.1 EIE84653.1 - 0.011 13.9 1.9 0.012 13.8 1.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Ima1_N PF09779.4 EIE84653.1 - 0.014 15.8 6.2 0.036 14.5 0.2 2.3 1 1 1 2 2 2 0 Ima1 N-terminal domain Zn_Tnp_IS1595 PF12760.2 EIE84653.1 - 0.015 15.0 0.3 0.031 14.0 0.2 1.6 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Syntaxin PF00804.20 EIE84653.1 - 0.018 15.1 4.5 0.033 14.3 3.1 1.3 1 0 0 1 1 1 0 Syntaxin Rubredoxin PF00301.15 EIE84653.1 - 0.03 14.1 0.6 0.22 11.4 0.0 2.5 3 0 0 3 3 3 0 Rubredoxin Phage_GP20 PF06810.6 EIE84653.1 - 0.03 13.7 2.6 0.046 13.1 1.8 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 FlxA PF14282.1 EIE84653.1 - 0.033 14.1 8.7 0.054 13.4 6.0 1.3 1 0 0 1 1 1 0 FlxA-like protein APG6 PF04111.7 EIE84653.1 - 0.036 13.1 2.3 0.044 12.8 1.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 AIP3 PF03915.8 EIE84653.1 - 0.036 12.9 1.7 0.051 12.4 1.2 1.3 1 0 0 1 1 1 0 Actin interacting protein 3 GLE1 PF07817.8 EIE84653.1 - 0.044 12.7 1.0 0.062 12.2 0.7 1.3 1 0 0 1 1 1 0 GLE1-like protein Elf1 PF05129.8 EIE84653.1 - 0.048 13.3 1.8 0.11 12.1 1.2 1.7 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like DUF4391 PF14335.1 EIE84653.1 - 0.05 12.9 2.2 0.069 12.5 1.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) Docking PF08990.6 EIE84653.1 - 0.053 12.7 0.8 0.088 12.0 0.5 1.4 1 0 0 1 1 1 0 Erythronolide synthase docking Rsc14 PF08586.5 EIE84653.1 - 0.057 13.9 1.6 2.1 8.8 0.9 2.6 2 1 0 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit Bcr-Abl_Oligo PF09036.5 EIE84653.1 - 0.068 13.1 0.3 0.12 12.3 0.2 1.4 1 0 0 1 1 1 0 Bcr-Abl oncoprotein oligomerisation domain zf-Sec23_Sec24 PF04810.10 EIE84653.1 - 0.069 12.7 1.2 0.25 10.9 0.0 2.2 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Noelin-1 PF12308.3 EIE84653.1 - 0.12 12.1 1.4 0.17 11.6 0.3 1.9 2 1 0 2 2 2 0 Neurogenesis glycoprotein Sgf11 PF08209.6 EIE84653.1 - 0.13 11.6 3.9 0.86 8.9 0.2 2.2 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zf-Dof PF02701.10 EIE84653.1 - 0.13 12.1 1.2 0.25 11.2 0.8 1.5 1 0 0 1 1 1 0 Dof domain, zinc finger DUF4140 PF13600.1 EIE84653.1 - 0.13 12.7 3.9 0.24 11.8 2.7 1.4 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF4164 PF13747.1 EIE84653.1 - 0.14 12.2 3.6 0.24 11.5 2.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) E2R135 PF11570.3 EIE84653.1 - 0.21 11.6 2.7 0.46 10.5 1.9 1.5 1 1 0 1 1 1 0 Coiled-coil receptor-binding R-domain of colicin E2 NPV_P10 PF05531.7 EIE84653.1 - 0.34 11.1 4.4 2.2 8.5 3.1 2.1 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF2175 PF09943.4 EIE84653.1 - 0.77 9.8 3.2 1.7 8.7 2.2 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) Mnd1 PF03962.10 EIE84653.1 - 0.84 9.2 4.6 1.2 8.7 3.2 1.2 1 0 0 1 1 1 0 Mnd1 family IncA PF04156.9 EIE84653.1 - 1 8.9 8.1 0.21 11.1 3.5 1.4 2 0 0 2 2 1 0 IncA protein Seryl_tRNA_N PF02403.17 EIE84653.1 - 1.4 8.9 5.5 0.62 10.0 2.2 1.6 2 0 0 2 2 1 0 Seryl-tRNA synthetase N-terminal domain TMF_DNA_bd PF12329.3 EIE84653.1 - 1.9 8.3 10.6 0.62 9.8 4.0 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Ribosomal_L29 PF00831.18 EIE84653.1 - 2.2 8.0 7.3 0.76 9.5 2.1 2.1 2 0 0 2 2 2 0 Ribosomal L29 protein TMF_TATA_bd PF12325.3 EIE84653.1 - 2.8 7.6 10.5 5.4 6.7 4.8 2.3 2 1 1 3 3 2 0 TATA element modulatory factor 1 TATA binding DivIC PF04977.10 EIE84653.1 - 3.2 7.2 7.6 4.9 6.6 2.7 2.2 1 1 1 2 2 2 0 Septum formation initiator zf-H2C2_2 PF13465.1 EIE84653.1 - 4 7.9 7.7 11 6.5 0.6 2.4 1 1 1 2 2 2 0 Zinc-finger double domain RTP PF02334.11 EIE84654.1 - 0.067 13.1 0.0 1 9.3 0.0 2.4 2 0 0 2 2 2 0 Replication terminator protein Transposase_mut PF00872.13 EIE84655.1 - 5.2e-07 28.5 0.3 9.1e-07 27.7 0.2 1.4 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.4 EIE84655.1 - 5.9e-07 29.5 0.0 1.6e-06 28.1 0.0 1.8 1 0 0 1 1 1 1 MULE transposase domain DDE_Tnp_IS240 PF13610.1 EIE84655.1 - 0.0032 17.4 0.1 0.98 9.3 0.0 2.7 3 0 0 3 3 3 2 DDE domain SWIM PF04434.12 EIE84655.1 - 0.0069 15.8 2.1 0.015 14.7 1.4 1.6 1 0 0 1 1 1 1 SWIM zinc finger FAR1 PF03101.10 EIE84655.1 - 0.017 15.5 2.2 0.017 15.5 1.5 2.0 2 0 0 2 2 2 0 FAR1 DNA-binding domain MFS_1 PF07690.11 EIE84657.1 - 6.2e-05 21.8 15.6 0.0032 16.2 10.8 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1700 PF08006.6 EIE84657.1 - 0.64 9.2 4.7 1 8.6 3.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) DivIC PF04977.10 EIE84659.1 - 0.0054 16.1 1.1 0.011 15.2 0.8 1.4 1 0 0 1 1 1 1 Septum formation initiator SlyX PF04102.7 EIE84659.1 - 0.011 16.1 1.2 0.033 14.5 0.8 1.8 1 0 0 1 1 1 0 SlyX DUF4164 PF13747.1 EIE84659.1 - 0.013 15.5 1.0 1.3 9.1 0.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) Rab5-bind PF09311.6 EIE84659.1 - 0.041 13.7 0.4 0.097 12.5 0.3 1.5 1 0 0 1 1 1 0 Rabaptin-like protein zf-MYND PF01753.13 EIE84661.1 - 5.1e-08 32.6 16.2 1.2e-07 31.4 11.2 1.7 1 0 0 1 1 1 1 MYND finger HTH_23 PF13384.1 EIE84663.1 - 1.3e-05 24.6 0.0 2.2e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.1 EIE84663.1 - 5.1e-05 23.1 0.0 8.3e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_1 PF01527.15 EIE84663.1 - 0.00066 19.5 0.0 0.001 18.9 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_Tnp_ISL3 PF13542.1 EIE84663.1 - 0.0052 15.9 0.1 0.01 15.0 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_30 PF13556.1 EIE84663.1 - 0.009 15.5 0.1 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain DUF1804 PF08822.6 EIE84663.1 - 0.044 13.5 0.0 0.087 12.5 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1804) Glyco_transf_15 PF01793.11 EIE84665.1 - 3.8e-132 440.2 15.3 4.6e-132 439.9 10.6 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase RVT_1 PF00078.22 EIE84666.1 - 6.5e-16 58.3 0.1 1.3e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.12 EIE84666.1 - 4.4e-09 36.3 0.1 1.2e-08 34.9 0.1 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein Asp_protease_2 PF13650.1 EIE84666.1 - 2.8e-05 24.5 0.0 6.1e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.5 EIE84666.1 - 0.0039 16.7 0.0 0.0089 15.5 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EIE84666.1 - 0.012 15.4 0.0 0.03 14.1 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease UBN2 PF14223.1 EIE84666.1 - 0.08 12.7 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Ribosomal_S10 PF00338.17 EIE84667.1 - 1.6e-31 107.9 0.7 1.9e-31 107.7 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e DUF4137 PF13593.1 EIE84672.1 - 7.3e-86 288.0 19.9 8.7e-86 287.8 13.8 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.11 EIE84672.1 - 1.1e-08 34.6 19.3 3.1e-08 33.2 10.1 2.3 2 0 0 2 2 2 2 Sodium Bile acid symporter family COX6B PF02297.12 EIE84673.1 - 1.1e-22 79.8 5.1 1.2e-22 79.6 3.6 1.0 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Pet191_N PF10203.4 EIE84673.1 - 0.0046 16.9 4.6 0.024 14.6 3.2 1.9 1 1 1 2 2 2 2 Cytochrome c oxidase assembly protein PET191 UPF0203 PF05254.7 EIE84673.1 - 0.91 9.4 6.0 0.26 11.1 0.3 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0203) zf-TFIIIC PF12660.2 EIE84674.1 - 2.7e-07 30.4 0.2 7.1e-07 29.0 0.1 1.7 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex LBP_BPI_CETP PF01273.20 EIE84674.1 - 0.063 12.6 0.1 0.6 9.4 0.0 2.3 2 0 0 2 2 2 0 LBP / BPI / CETP family, N-terminal domain Hemerythrin PF01814.18 EIE84675.1 - 0.086 13.0 0.5 0.086 13.0 0.3 2.0 2 0 0 2 2 2 0 Hemerythrin HHE cation binding domain ThiS PF02597.15 EIE84675.1 - 0.36 11.2 5.1 0.19 12.2 0.4 2.5 1 1 2 3 3 3 0 ThiS family Glyco_hydro_3 PF00933.16 EIE84676.1 - 4.3e-70 236.0 0.3 4.3e-38 131.0 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EIE84676.1 - 2.3e-66 223.5 0.0 3.9e-66 222.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EIE84676.1 - 2.3e-19 69.0 0.0 4.3e-19 68.2 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF481 PF04338.7 EIE84676.1 - 0.011 15.5 0.2 0.025 14.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF481 PCI PF01399.22 EIE84677.1 - 2.3e-13 50.3 0.5 1.6e-12 47.6 0.0 2.4 2 1 0 2 2 2 1 PCI domain FlaC_arch PF05377.6 EIE84677.1 - 0.2 11.5 1.5 2 8.3 0.0 2.7 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Zn_clus PF00172.13 EIE84678.1 - 2.1e-08 33.9 8.7 3.7e-08 33.1 6.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L18e PF00828.14 EIE84680.1 - 1.4e-14 54.6 0.1 1.4e-14 54.6 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 SET PF00856.23 EIE84681.1 - 7.1e-06 26.4 0.2 0.0013 19.0 0.0 3.1 2 1 0 2 2 2 2 SET domain Malic_M PF03949.10 EIE84682.1 - 5.9e-80 268.5 0.0 7.7e-80 268.1 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 EIE84682.1 - 2.9e-60 202.9 0.0 4.8e-60 202.2 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain PDEase_I PF00233.14 EIE84683.1 - 8.4e-50 169.7 3.1 3.1e-26 92.5 3.7 2.2 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.17 EIE84683.1 - 0.0084 16.1 0.0 0.03 14.3 0.0 2.0 1 0 0 1 1 1 1 HD domain WD40 PF00400.27 EIE84684.1 - 4.1e-94 305.4 20.2 6.4e-16 57.5 0.2 8.4 8 1 0 8 8 8 8 WD domain, G-beta repeat Nup160 PF11715.3 EIE84684.1 - 9.1e-10 37.2 6.9 0.031 12.4 0.0 5.5 1 1 5 6 6 6 4 Nucleoporin Nup120/160 eIF2A PF08662.6 EIE84684.1 - 1.5e-09 37.8 0.4 0.0092 15.7 0.0 4.0 3 1 1 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 EIE84684.1 - 1.3e-06 27.7 0.4 0.23 10.4 0.0 4.3 2 2 2 4 4 4 2 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.7 EIE84684.1 - 3.3e-05 23.4 2.3 1.5 8.5 0.1 4.3 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat IKI3 PF04762.7 EIE84684.1 - 0.0066 14.3 1.3 0.98 7.1 0.2 2.6 2 1 0 2 2 2 2 IKI3 family NLE PF08154.7 EIE84684.1 - 0.0071 16.3 0.0 0.29 11.1 0.0 2.4 1 1 0 1 1 1 1 NLE (NUC135) domain Nucleoporin_N PF08801.6 EIE84684.1 - 0.012 14.3 3.6 6 5.4 0.0 3.4 2 1 1 3 3 3 0 Nup133 N terminal like Proteasome_A_N PF10584.4 EIE84684.1 - 0.012 14.8 0.5 1.7 8.0 0.0 3.4 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature DUF3312 PF11768.3 EIE84684.1 - 0.033 12.4 0.0 5.4 5.1 0.0 2.8 2 2 1 3 3 3 0 Protein of unknown function (DUF3312) Cytochrom_D1 PF02239.11 EIE84684.1 - 0.045 12.0 0.4 0.62 8.2 0.0 2.6 2 2 2 4 4 4 0 Cytochrome D1 heme domain OSCP PF00213.13 EIE84688.1 - 1.4e-45 155.2 2.9 1.6e-45 155.0 2.0 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit vATP-synt_E PF01991.13 EIE84688.1 - 0.014 14.7 1.3 0.12 11.6 0.2 2.0 1 1 0 2 2 2 0 ATP synthase (E/31 kDa) subunit CBM_21 PF03370.8 EIE84690.1 - 2.3e-17 62.9 0.0 4.6e-17 62.0 0.0 1.5 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit CARDB PF07705.6 EIE84690.1 - 0.046 13.7 0.2 0.16 12.0 0.1 1.8 1 0 0 1 1 1 0 CARDB TPR_11 PF13414.1 EIE84691.1 - 3.7e-20 71.3 0.2 5.7e-20 70.7 0.1 1.2 1 0 0 1 1 1 1 TPR repeat TPR_1 PF00515.23 EIE84691.1 - 4.3e-15 54.5 0.4 6.9e-11 41.2 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 EIE84691.1 - 1e-11 43.8 0.1 1.3e-06 27.8 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 EIE84691.1 - 1.1e-05 25.2 0.6 0.17 12.1 0.0 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EIE84691.1 - 1.7e-05 24.2 0.2 0.00036 20.1 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EIE84691.1 - 2e-05 24.4 0.3 0.0039 17.0 0.0 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 EIE84691.1 - 3.3e-05 24.4 0.0 4.5e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat Apc3 PF12895.2 EIE84691.1 - 0.00011 22.3 0.3 0.00022 21.2 0.2 1.3 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EIE84691.1 - 0.00085 18.9 0.1 0.11 12.3 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 EIE84691.1 - 0.00098 18.3 0.1 1.3 8.3 0.0 2.4 2 0 0 2 2 2 2 SHNi-TPR TPR_19 PF14559.1 EIE84691.1 - 0.0049 17.1 0.0 0.0065 16.7 0.0 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_9 PF13371.1 EIE84691.1 - 0.024 14.4 0.0 0.033 14.0 0.0 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF1896 PF08989.5 EIE84691.1 - 0.041 13.7 0.4 0.093 12.5 0.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1896) TPR_14 PF13428.1 EIE84691.1 - 0.062 13.9 0.0 5.5 7.9 0.0 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat SNAP PF14938.1 EIE84691.1 - 0.065 12.3 0.1 0.076 12.1 0.1 1.1 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP RNB PF00773.14 EIE84692.1 - 1.5e-76 257.8 0.2 4e-76 256.3 0.1 1.8 1 0 0 1 1 1 1 RNB domain OB_RNB PF08206.6 EIE84692.1 - 0.0058 16.1 0.0 0.015 14.7 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease B OB domain Acyltransferase PF01553.16 EIE84694.1 - 1.2e-14 53.8 0.1 6.8e-13 48.2 0.1 2.2 1 1 0 1 1 1 1 Acyltransferase LRR_5 PF13306.1 EIE84694.1 - 0.081 12.6 0.1 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Leucine rich repeats (6 copies) TP_methylase PF00590.15 EIE84695.1 - 3.3e-45 154.3 0.1 5.1e-45 153.7 0.1 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Sirohm_synth_C PF14823.1 EIE84695.1 - 1.4e-17 62.7 0.0 2.8e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal NAD_binding_7 PF13241.1 EIE84695.1 - 3.4e-11 43.3 0.0 9.5e-11 41.8 0.0 1.8 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_M PF14824.1 EIE84695.1 - 0.00067 18.5 0.3 0.00067 18.5 0.2 2.3 3 0 0 3 3 3 1 Sirohaem biosynthesis protein central DUF1349 PF07081.6 EIE84696.1 - 0.054 12.8 0.0 0.12 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1349) ATP_bind_3 PF01171.15 EIE84697.1 - 2.2e-18 66.3 0.0 4e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 PP-loop family DUF2392 PF10288.4 EIE84697.1 - 0.01 16.1 0.0 0.019 15.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2392) tRNA_Me_trans PF03054.11 EIE84697.1 - 0.024 13.1 0.0 0.037 12.5 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase TF_Zn_Ribbon PF08271.7 EIE84697.1 - 3.6 6.9 8.1 4.4 6.7 0.4 3.2 3 0 0 3 3 3 0 TFIIB zinc-binding zf-UBR PF02207.15 EIE84697.1 - 4.9 6.9 8.3 2 8.1 1.0 2.5 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) ProQ PF04352.8 EIE84698.1 - 1 9.0 0.0 1 9.0 0.0 3.1 2 1 1 3 3 3 0 ProQ/FINO family MFS_1 PF07690.11 EIE84699.1 - 3.8e-39 134.4 33.5 3.8e-39 134.4 23.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PALP PF00291.20 EIE84701.1 - 5.8e-49 166.9 0.1 1.4e-48 165.7 0.1 1.6 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.23 EIE84701.1 - 8.5e-13 47.8 0.3 1.3e-07 31.3 0.0 2.9 3 0 0 3 3 3 2 CBS domain DZF PF07528.9 EIE84701.1 - 0.056 12.8 0.0 0.097 12.0 0.0 1.4 1 0 0 1 1 1 0 DZF domain Glyco_tran_WecB PF03808.8 EIE84701.1 - 0.071 12.5 0.0 0.16 11.3 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family Cytochrome-c551 PF10643.4 EIE84702.1 - 0.21 10.8 0.6 0.24 10.6 0.4 1.1 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 LysM PF01476.15 EIE84703.1 - 0.00027 20.7 0.0 0.00047 19.9 0.0 1.4 1 0 0 1 1 1 1 LysM domain Pol_alpha_B_N PF08418.5 EIE84703.1 - 0.063 12.8 17.7 0.079 12.4 12.2 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal DNA_pol_viral_N PF00242.12 EIE84703.1 - 0.26 10.2 13.0 0.34 9.8 9.0 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Dicty_REP PF05086.7 EIE84703.1 - 2.2 5.9 15.9 3.8 5.1 11.0 1.4 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein PIH1 PF08190.7 EIE84703.1 - 2.8 7.2 17.3 4.2 6.7 12.0 1.2 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 DDHD PF02862.12 EIE84703.1 - 7.2 6.3 10.9 11 5.7 7.5 1.3 1 0 0 1 1 1 0 DDHD domain HTH_32 PF13565.1 EIE84704.1 - 9.2e-06 26.3 0.2 1.2e-05 25.9 0.1 1.2 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.1 EIE84704.1 - 1.7e-05 24.9 0.1 2.4e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.1 EIE84704.1 - 0.072 13.1 0.1 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HHH_4 PF14490.1 EIE84704.1 - 0.14 11.9 0.0 0.59 9.9 0.0 2.2 1 1 0 1 1 1 0 Helix-hairpin-helix containing domain LsmAD PF06741.8 EIE84706.1 - 3.9e-25 87.7 0.1 3.9e-25 87.7 0.1 2.6 3 0 0 3 3 3 1 LsmAD domain SM-ATX PF14438.1 EIE84706.1 - 1.4e-09 37.7 0.0 4e-09 36.2 0.0 1.9 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF4101 PF13355.1 EIE84706.1 - 2.2 8.7 9.9 1.9 8.9 4.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF4101) Ribosomal_L19 PF01245.15 EIE84707.1 - 2.2e-26 91.8 0.1 2.7e-26 91.5 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L19 Peptidase_M28 PF04389.12 EIE84708.1 - 1.9e-32 112.4 0.0 3.5e-32 111.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M42 PF05343.9 EIE84708.1 - 2.4e-05 23.2 0.0 0.00077 18.3 0.0 2.8 2 1 2 4 4 4 1 M42 glutamyl aminopeptidase Peptidase_M20 PF01546.23 EIE84708.1 - 8.7e-05 22.1 0.0 0.00015 21.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 OppC_N PF12911.2 EIE84708.1 - 0.066 12.5 0.0 0.066 12.5 0.0 3.3 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C DDE_3 PF13358.1 EIE84709.1 - 1.7e-12 47.3 0.0 2.9e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE84709.1 - 5.8e-09 35.8 2.9 1.2e-08 34.8 2.0 1.5 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.1 EIE84709.1 - 0.012 15.1 0.1 0.11 12.1 0.0 2.4 2 0 0 2 2 2 0 Homeodomain-like domain SpoIIID PF12116.3 EIE84709.1 - 0.052 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Stage III sporulation protein D Lge1 PF11488.3 EIE84709.1 - 0.056 13.6 0.2 0.15 12.2 0.0 1.7 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 HTH_38 PF13936.1 EIE84709.1 - 0.075 12.5 0.3 0.22 11.0 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain Ras PF00071.17 EIE84710.1 - 8.9e-56 187.7 0.1 1e-55 187.5 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIE84710.1 - 5.1e-17 62.4 0.0 7.9e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIE84710.1 - 1.7e-12 46.9 0.1 2.1e-12 46.6 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EIE84710.1 - 0.003 16.7 0.0 0.0053 15.9 0.0 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EIE84710.1 - 0.0031 16.7 0.2 0.0049 16.1 0.2 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 EIE84710.1 - 0.02 14.3 0.7 0.13 11.7 0.5 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Syncollin PF15138.1 EIE84710.1 - 0.037 13.9 0.0 0.1 12.4 0.0 1.7 2 0 0 2 2 2 0 Syncollin CBS PF00571.23 EIE84711.1 - 2.1e-40 136.2 6.6 2.6e-09 36.7 0.0 4.5 4 1 0 4 4 4 4 CBS domain KaiC PF06745.8 EIE84711.1 - 0.012 14.7 0.0 0.023 13.8 0.0 1.5 1 0 0 1 1 1 0 KaiC Fungal_trans PF04082.13 EIE84712.1 - 1.8e-21 76.1 5.3 7.5e-21 74.1 3.7 2.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIE84712.1 - 1.2e-10 41.0 6.0 2.3e-10 40.1 4.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BAF1_ABF1 PF04684.8 EIE84712.1 - 0.17 10.7 23.7 0.34 9.7 16.4 1.4 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Zip PF02535.17 EIE84712.1 - 0.6 9.0 6.1 1.8 7.5 4.1 1.8 2 0 0 2 2 2 0 ZIP Zinc transporter MRG PF05712.8 EIE84713.1 - 5.4e-13 48.2 0.2 1.2e-12 47.1 0.2 1.6 1 0 0 1 1 1 1 MRG MBOAT_2 PF13813.1 EIE84713.1 - 2.9e-08 33.6 3.0 5.9e-08 32.6 2.1 1.6 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family ESAG1 PF03238.8 EIE84713.1 - 0.017 14.4 0.2 0.024 13.9 0.1 1.2 1 0 0 1 1 1 0 ESAG protein DUF3272 PF11676.3 EIE84713.1 - 0.037 14.0 6.3 1.3 9.1 0.4 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF3272) Hrs_helical PF12210.3 EIE84713.1 - 0.12 12.6 1.2 30 4.9 0.0 2.2 2 0 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Med19 PF10278.4 EIE84713.1 - 0.44 10.2 5.8 0.67 9.6 4.0 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 tRNA-synt_1 PF00133.17 EIE84714.1 - 8.6e-40 136.3 5.6 7e-29 100.2 0.8 3.5 3 1 0 3 3 3 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EIE84714.1 - 3.1e-17 62.3 0.7 2.3e-10 39.6 0.0 2.7 3 0 0 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 EIE84714.1 - 3.8e-07 29.5 0.0 8.2e-07 28.4 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain SWIRM PF04433.12 EIE84715.1 - 2.7e-19 69.0 0.2 7.3e-19 67.6 0.1 1.8 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-bind_6 PF13921.1 EIE84715.1 - 1.7e-08 34.4 0.1 7.6e-08 32.3 0.1 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EIE84715.1 - 5e-08 32.8 0.4 1.2e-07 31.6 0.1 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain ZZ PF00569.12 EIE84715.1 - 1.3e-05 24.6 3.8 2.6e-05 23.6 2.7 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type Cytochrome_C7 PF14522.1 EIE84715.1 - 0.017 14.7 0.2 0.046 13.3 0.2 1.7 1 0 0 1 1 1 0 Cytochrome c7 Paired_CXXCH_1 PF09699.5 EIE84715.1 - 0.21 11.1 2.6 0.48 9.9 1.8 1.5 1 0 0 1 1 1 0 Doubled CXXCH motif (Paired_CXXCH_1) DUF2151 PF10221.4 EIE84716.1 - 2.2e-05 22.8 2.4 0.017 13.3 0.8 2.6 3 0 0 3 3 3 2 Cell cycle and development regulator FGE-sulfatase PF03781.11 EIE84718.1 - 2.4e-38 132.0 3.8 3.3e-38 131.5 2.7 1.1 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 FBA_2 PF07735.12 EIE84718.1 - 0.16 11.8 0.0 0.53 10.1 0.0 1.7 2 0 0 2 2 2 0 F-box associated Trehalose_PPase PF02358.11 EIE84719.1 - 8.4e-41 139.4 0.0 1e-40 139.1 0.0 1.0 1 0 0 1 1 1 1 Trehalose-phosphatase MFS_1 PF07690.11 EIE84721.1 - 3.3e-44 151.0 44.0 6e-44 150.1 29.5 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIE84721.1 - 3e-16 59.0 13.5 3e-16 59.0 9.4 2.5 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EIE84721.1 - 4.1e-16 58.3 27.2 5.5e-16 57.8 18.9 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF605 PF04652.11 EIE84723.1 - 0.025 13.9 1.8 0.03 13.7 1.2 1.1 1 0 0 1 1 1 0 Vta1 like GET2 PF08690.5 EIE84723.1 - 0.035 13.3 1.4 0.04 13.1 1.0 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 MFS_1 PF07690.11 EIE84724.1 - 0.00049 18.9 34.4 0.0016 17.2 6.5 3.3 2 2 1 3 3 3 2 Major Facilitator Superfamily DUF438 PF04282.8 EIE84724.1 - 0.0018 18.0 0.0 0.0029 17.3 0.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF438) PUCC PF03209.10 EIE84724.1 - 0.012 14.4 3.5 0.012 14.3 0.2 2.2 2 1 0 2 2 2 0 PUCC protein TFCD_C PF12612.3 EIE84724.1 - 0.042 13.2 0.0 0.07 12.5 0.0 1.3 1 0 0 1 1 1 0 Tubulin folding cofactor D C terminal Abp2 PF09441.5 EIE84725.1 - 1e-06 28.7 0.0 2e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 ARS binding protein 2 Ubiquitin_3 PF14836.1 EIE84725.1 - 0.028 14.0 0.1 0.063 12.9 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain IncA PF04156.9 EIE84725.1 - 0.67 9.5 5.3 1.2 8.7 3.6 1.4 1 1 0 1 1 1 0 IncA protein DUF4613 PF15390.1 EIE84725.1 - 4.5 5.3 10.3 6 4.9 7.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Mito_carr PF00153.22 EIE84726.1 - 3.5e-31 106.7 0.4 8.8e-19 67.0 0.0 2.2 2 0 0 2 2 2 2 Mitochondrial carrier protein LIP PF03583.9 EIE84726.1 - 0.095 11.8 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Secretory lipase Myb_DNA-bind_6 PF13921.1 EIE84727.1 - 2.5e-06 27.5 1.3 6.9e-05 22.8 0.0 2.7 2 1 1 3 3 3 2 Myb-like DNA-binding domain DUF3399 PF11879.3 EIE84727.1 - 1.8 8.8 4.6 0.41 10.9 0.2 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF3399) zf-RVT PF13966.1 EIE84728.1 - 0.066 13.5 0.1 0.073 13.3 0.1 1.2 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase Kinesin PF00225.18 EIE84730.1 - 1.2e-87 293.7 1.5 1.8e-87 293.1 1.1 1.3 1 0 0 1 1 1 1 Kinesin motor domain KOW PF00467.24 EIE84731.1 - 4.1e-05 23.1 1.7 9.3e-05 21.9 1.1 1.6 1 0 0 1 1 1 1 KOW motif LSM PF01423.17 EIE84731.1 - 0.031 13.8 0.0 0.049 13.1 0.0 1.5 1 0 0 1 1 1 0 LSM domain KH_1 PF00013.24 EIE84732.1 - 1.7e-19 69.2 0.0 2.3e-10 39.9 0.1 4.5 4 0 0 4 4 4 3 KH domain KH_3 PF13014.1 EIE84732.1 - 6.4e-14 51.2 2.4 4.5e-08 32.5 0.1 4.4 4 0 0 4 4 4 2 KH domain KH_2 PF07650.12 EIE84732.1 - 0.0047 16.4 0.0 0.44 10.1 0.0 2.9 2 0 0 2 2 2 1 KH domain KOW PF00467.24 EIE84733.1 - 7.2e-11 41.3 2.8 7.2e-11 41.3 1.9 1.7 2 1 0 2 2 2 1 KOW motif DUF1442 PF07279.6 EIE84733.1 - 0.045 12.8 0.9 0.056 12.5 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1442) Arm PF00514.18 EIE84734.1 - 1.1e-17 63.0 6.8 0.026 14.3 0.0 7.7 8 0 0 8 8 8 5 Armadillo/beta-catenin-like repeat ANTH PF07651.11 EIE84734.1 - 0.0056 15.4 2.2 0.73 8.4 0.2 2.4 1 1 1 2 2 2 2 ANTH domain Atx10homo_assoc PF09759.4 EIE84734.1 - 0.019 14.7 3.6 0.95 9.2 0.0 4.0 3 1 1 4 4 4 0 Spinocerebellar ataxia type 10 protein domain HEAT PF02985.17 EIE84734.1 - 0.023 14.7 2.6 0.062 13.3 0.0 3.3 3 0 0 3 3 3 0 HEAT repeat Ric8 PF10165.4 EIE84734.1 - 0.047 12.5 4.8 3.4 6.3 3.3 2.8 1 1 0 1 1 1 0 Guanine nucleotide exchange factor synembryn V-ATPase_H_C PF11698.3 EIE84734.1 - 0.1 12.5 5.3 1.2 9.0 0.1 4.0 3 1 1 4 4 4 0 V-ATPase subunit H HEAT_EZ PF13513.1 EIE84734.1 - 0.54 10.8 2.4 9.1 6.9 0.0 3.8 3 1 1 4 4 4 0 HEAT-like repeat DUF1079 PF06435.6 EIE84736.1 - 1.5 8.8 4.6 1.2 9.1 1.6 1.8 2 0 0 2 2 2 0 Repeat of unknown function (DUF1079) GST_N_3 PF13417.1 EIE84737.1 - 7e-15 55.0 0.0 1.7e-14 53.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIE84737.1 - 7.5e-07 29.0 0.0 1.5e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EIE84737.1 - 0.0087 16.2 0.0 0.027 14.6 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain HlyIII PF03006.15 EIE84739.1 - 1.2e-46 158.8 22.7 3.8e-42 144.1 10.2 2.1 1 1 1 2 2 2 2 Haemolysin-III related DUF4231 PF14015.1 EIE84739.1 - 0.11 12.5 0.2 1.7 8.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) c-SKI_SMAD_bind PF08782.5 EIE84739.1 - 1.7 8.7 5.2 0.26 11.4 0.7 1.8 2 0 0 2 2 2 0 c-SKI Smad4 binding domain DPBB_1 PF03330.13 EIE84740.1 - 4.4e-15 55.4 0.1 7.4e-15 54.7 0.1 1.4 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EIE84740.1 - 0.0016 18.1 0.4 0.0029 17.2 0.0 1.5 2 0 0 2 2 2 1 Barwin family PDR_CDR PF06422.7 EIE84740.1 - 0.13 11.9 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 CDR ABC transporter Mob1_phocein PF03637.12 EIE84742.1 - 1.1e-43 148.9 1.5 1.5e-38 132.2 0.3 2.0 1 1 1 2 2 2 2 Mob1/phocein family HEAT PF02985.17 EIE84744.1 - 1.2e-51 168.1 30.2 0.00012 21.8 0.1 22.6 24 0 0 24 24 24 11 HEAT repeat DUF3554 PF12074.3 EIE84744.1 - 4.1e-38 131.6 7.5 7.8e-37 127.4 3.2 4.1 4 0 0 4 4 4 1 Domain of unknown function (DUF3554) HEAT_2 PF13646.1 EIE84744.1 - 1.8e-35 121.0 39.5 1.1e-06 28.8 0.2 15.6 10 4 7 17 17 17 10 HEAT repeats HEAT_EZ PF13513.1 EIE84744.1 - 1.2e-30 105.1 47.6 0.0024 18.3 0.0 18.0 17 3 5 22 22 18 9 HEAT-like repeat CLASP_N PF12348.3 EIE84744.1 - 1e-14 54.4 0.2 0.00097 18.5 0.0 7.5 6 2 1 8 8 8 2 CLASP N terminal Vac14_Fab1_bd PF12755.2 EIE84744.1 - 9.2e-13 48.4 0.7 0.074 13.4 0.0 8.5 7 2 2 9 9 9 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 EIE84744.1 - 3.2e-08 33.6 5.0 0.055 13.3 0.1 6.8 7 1 0 8 8 8 2 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.4 EIE84744.1 - 9.9e-08 32.0 1.1 0.39 10.5 0.0 5.9 4 2 1 5 5 5 2 Parkin co-regulated protein Ipi1_N PF12333.3 EIE84744.1 - 3.3e-05 23.7 0.0 0.23 11.4 0.0 5.6 5 0 0 5 5 5 1 Rix1 complex component involved in 60S ribosome maturation Cohesin_HEAT PF12765.2 EIE84744.1 - 0.02 14.8 9.4 19 5.3 0.1 5.8 5 0 0 5 5 5 0 HEAT repeat associated with sister chromatid cohesion HEAT_PBS PF03130.11 EIE84744.1 - 0.7 10.5 12.0 1.9e+02 2.9 0.1 8.7 8 0 0 8 8 7 0 PBS lyase HEAT-like repeat ABC1 PF03109.11 EIE84745.1 - 5.6e-34 116.6 0.0 2.3e-33 114.7 0.0 2.0 2 0 0 2 2 2 1 ABC1 family Oxidored_q1_N PF00662.15 EIE84745.1 - 0.24 11.0 0.8 0.56 9.8 0.6 1.6 1 0 0 1 1 1 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus Aldedh PF00171.17 EIE84746.1 - 1.4e-114 383.0 0.0 1.7e-114 382.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Mo25 PF08569.6 EIE84747.1 - 5.4e-113 377.4 13.1 1.1e-110 369.8 6.9 2.0 1 1 1 2 2 2 2 Mo25-like DUF544 PF04424.8 EIE84747.1 - 0.12 12.1 3.4 0.49 10.2 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF544) Lipocalin_7 PF14651.1 EIE84747.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family RasGEF PF00617.14 EIE84749.1 - 1.8e-44 151.7 1.0 3.1e-44 150.9 0.7 1.3 1 0 0 1 1 1 1 RasGEF domain CPL PF08144.6 EIE84752.1 - 3.4e-35 121.0 2.4 1.1e-34 119.4 0.3 2.7 2 0 0 2 2 2 1 CPL (NUC119) domain PUF PF00806.14 EIE84752.1 - 7.7e-06 25.1 1.5 2.3 7.8 0.0 5.4 6 0 0 6 6 6 3 Pumilio-family RNA binding repeat DUF4050 PF13259.1 EIE84752.1 - 0.015 15.2 0.8 0.024 14.5 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) Bestrophin PF01062.16 EIE84752.1 - 0.037 12.9 2.1 1.1 8.1 0.0 2.3 2 0 0 2 2 2 0 Bestrophin, RFP-TM, chloride channel TraH PF06122.6 EIE84752.1 - 0.12 11.1 2.7 0.22 10.2 1.9 1.5 1 0 0 1 1 1 0 Conjugative relaxosome accessory transposon protein MGDG_synth PF06925.6 EIE84752.1 - 0.14 12.0 1.6 8.5 6.2 0.1 2.4 1 1 1 2 2 2 0 Monogalactosyldiacylglycerol (MGDG) synthase EF_TS PF00889.14 EIE84753.1 - 2.7e-32 111.9 0.3 2.7e-26 92.2 0.0 2.4 1 1 1 2 2 2 2 Elongation factor TS UBA PF00627.26 EIE84753.1 - 0.032 14.0 0.0 0.065 13.0 0.0 1.6 1 0 0 1 1 1 0 UBA/TS-N domain Ribosomal_L7Ae PF01248.21 EIE84754.1 - 5.7e-27 93.0 0.0 6.6e-27 92.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family UCH PF00443.24 EIE84755.1 - 9.9e-68 228.1 0.7 1.1e-46 159.1 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 EIE84755.1 - 2.6e-18 66.2 0.5 9.2e-18 64.4 0.4 2.0 1 0 0 1 1 1 1 DUSP domain UCH_1 PF13423.1 EIE84755.1 - 8.6e-18 64.7 0.0 1.3e-07 31.3 0.0 2.6 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.1 EIE84755.1 - 1.9e-08 34.0 3.4 6.2e-07 29.0 0.0 2.8 3 0 0 3 3 3 2 Ubiquitin-specific protease C-terminal Cys_rich_KTR PF14205.1 EIE84755.1 - 0.14 11.6 1.5 3.9 6.9 0.1 2.7 3 0 0 3 3 3 0 Cysteine-rich KTR Ribosomal_L14e PF01929.12 EIE84756.1 - 7.9e-25 87.0 3.6 1.2e-24 86.4 2.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 EIE84756.1 - 8.1e-06 25.3 0.3 2.1e-05 24.0 0.2 1.7 1 0 0 1 1 1 1 KOW motif LMWPc PF01451.16 EIE84758.1 - 0.026 14.8 0.3 0.053 13.8 0.2 1.5 1 0 0 1 1 1 0 Low molecular weight phosphotyrosine protein phosphatase Imm39 PF15600.1 EIE84758.1 - 0.038 13.8 3.4 0.081 12.7 2.3 1.6 1 0 0 1 1 1 0 Immunity protein 39 Phage_Gp23 PF10669.4 EIE84758.1 - 0.13 12.3 3.9 0.095 12.8 0.9 2.1 1 1 1 2 2 2 0 Protein gp23 (Bacteriophage A118) DUF4358 PF14270.1 EIE84758.1 - 1.2 9.0 8.4 0.21 11.4 2.7 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4358) Pedibin PF08182.6 EIE84758.1 - 3.4 7.2 8.8 8.2 6.0 1.1 3.1 3 0 0 3 3 3 0 Pedibin/Hym-346 family Pyr_redox_2 PF07992.9 EIE84759.1 - 1.7e-22 80.3 0.1 8.7e-12 45.3 0.0 3.5 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EIE84759.1 - 1.8e-14 53.9 0.2 3.8e-12 46.4 0.1 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EIE84759.1 - 0.00032 20.8 1.3 0.43 10.6 0.0 3.2 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIE84759.1 - 0.01 14.3 0.6 0.089 11.2 0.0 2.3 1 1 1 2 2 2 0 HI0933-like protein NAD_binding_9 PF13454.1 EIE84759.1 - 0.012 15.4 0.5 1.5 8.5 0.0 2.8 3 0 0 3 3 3 0 FAD-NAD(P)-binding TPPII_N PF12583.3 EIE84759.1 - 0.07 13.2 0.1 0.18 11.9 0.0 1.6 2 0 0 2 2 2 0 Tripeptidyl peptidase II N terminal DAO PF01266.19 EIE84759.1 - 0.36 9.6 3.4 9.1 5.0 0.0 3.3 2 1 2 4 4 4 0 FAD dependent oxidoreductase FA_desaturase PF00487.19 EIE84760.1 - 1e-16 61.1 24.6 1.8e-16 60.3 17.0 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 EIE84760.1 - 1.3e-16 60.1 0.0 3.1e-16 58.9 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain F1F0-ATPsyn_F PF10791.4 EIE84761.1 - 2.5e-30 104.5 0.1 2.8e-30 104.3 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.4 EIE84761.1 - 5.2e-06 26.4 0.0 6.6e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial F1F0-ATP synthase, subunit f RTC4 PF14474.1 EIE84762.1 - 2.9e-14 53.0 0.3 7.9e-14 51.6 0.0 1.8 2 0 0 2 2 2 1 RTC4-like domain DUF3510 PF12022.3 EIE84762.1 - 0.034 14.2 5.4 0.36 10.9 1.3 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF3510) NYD-SP28 PF14772.1 EIE84762.1 - 0.38 10.8 7.3 0.92 9.6 4.0 2.3 2 0 0 2 2 2 0 Sperm tail Dsl1_C PF11989.3 EIE84764.1 - 0.041 13.0 0.6 0.059 12.5 0.4 1.2 1 0 0 1 1 1 0 Retrograde transport protein Dsl1 C terminal Stk19 PF10494.4 EIE84764.1 - 0.078 12.3 0.2 0.42 9.9 0.0 2.0 2 0 0 2 2 2 0 Serine-threonine protein kinase 19 Herpes_capsid PF06112.6 EIE84764.1 - 0.087 12.8 2.6 0.16 11.9 1.7 1.5 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein G-alpha PF00503.15 EIE84765.1 - 1.7e-128 428.6 10.3 2e-128 428.3 7.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EIE84765.1 - 1.7e-13 50.2 12.1 5.2e-11 42.0 0.2 3.8 2 2 2 4 4 4 2 ADP-ribosylation factor family Miro PF08477.8 EIE84765.1 - 0.00014 22.2 0.2 0.61 10.5 0.0 2.8 2 1 0 2 2 2 2 Miro-like protein Gtr1_RagA PF04670.7 EIE84765.1 - 0.00053 19.2 6.4 0.014 14.5 0.5 2.4 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region zf-CHC2 PF01807.15 EIE84765.1 - 0.0026 17.2 0.0 0.011 15.3 0.0 2.0 2 0 0 2 2 2 1 CHC2 zinc finger MMR_HSR1 PF01926.18 EIE84765.1 - 0.024 14.5 0.3 0.88 9.5 0.2 2.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.1 EIE84765.1 - 0.032 13.7 0.0 0.065 12.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Na_Ca_ex PF01699.19 EIE84766.1 - 2.5e-20 72.4 16.1 3.6e-20 72.0 11.2 1.2 1 0 0 1 1 1 1 Sodium/calcium exchanger protein DUF975 PF06161.6 EIE84766.1 - 4.3 7.0 11.1 6.9 6.3 7.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF975) AA_permease PF00324.16 EIE84767.1 - 1.9e-119 399.1 48.4 2.4e-119 398.8 33.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EIE84767.1 - 3.4e-40 137.8 49.4 4e-40 137.6 34.2 1.0 1 0 0 1 1 1 1 Amino acid permease AAA_16 PF13191.1 EIE84768.1 - 4.3e-09 36.6 0.1 1.2e-07 31.8 0.1 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EIE84768.1 - 2.5e-05 24.4 2.5 0.035 14.2 0.0 3.3 4 0 0 4 4 4 2 AAA domain TPR_12 PF13424.1 EIE84768.1 - 0.0018 18.1 1.5 0.52 10.2 0.0 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat AAA_17 PF13207.1 EIE84768.1 - 0.0051 17.6 0.0 0.026 15.3 0.0 2.3 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EIE84768.1 - 0.029 14.5 0.0 0.083 13.0 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.1 EIE84768.1 - 0.05 13.4 0.1 0.16 11.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EIE84768.1 - 0.053 12.9 0.0 0.16 11.3 0.0 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein NACHT PF05729.7 EIE84768.1 - 0.062 12.9 0.0 3.1 7.4 0.0 2.4 2 0 0 2 2 2 0 NACHT domain AAA_25 PF13481.1 EIE84768.1 - 0.067 12.5 0.0 0.23 10.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EIE84768.1 - 0.11 11.9 0.0 0.27 10.7 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain UBN2 PF14223.1 EIE84769.1 - 0.033 13.9 0.1 0.073 12.8 0.1 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Exo_endo_phos PF03372.18 EIE84770.1 - 2.7e-13 50.4 0.5 6e-13 49.2 0.3 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RVT_1 PF00078.22 EIE84770.1 - 3e-13 49.6 1.3 4e-06 26.3 0.0 3.2 2 1 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EIE84770.1 - 9.7e-07 28.4 0.0 3.5e-06 26.6 0.0 2.1 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase zf-CCHC PF00098.18 EIE84770.1 - 0.0015 18.3 12.0 0.002 17.9 3.1 2.7 2 0 0 2 2 2 2 Zinc knuckle HTH_29 PF13551.1 EIE84771.1 - 0.011 15.8 0.1 0.02 15.0 0.1 1.4 1 0 0 1 1 1 0 Winged helix-turn helix UBN2_2 PF14227.1 EIE84772.1 - 0.056 12.9 0.0 0.086 12.3 0.0 1.4 1 1 0 1 1 1 0 gag-polypeptide of LTR copia-type DDE_3 PF13358.1 EIE84773.1 - 4.7e-20 71.8 0.0 9e-20 70.9 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE84773.1 - 9.4e-16 57.6 1.1 4.4e-15 55.4 0.2 2.4 3 0 0 3 3 2 1 Transposase HTH_29 PF13551.1 EIE84773.1 - 4e-06 26.9 0.2 1.3e-05 25.3 0.1 1.9 2 0 0 2 2 1 1 Winged helix-turn helix HTH_38 PF13936.1 EIE84773.1 - 8.8e-05 21.9 0.1 0.00025 20.5 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_32 PF13565.1 EIE84773.1 - 0.00047 20.8 4.5 0.0077 17.0 0.1 3.7 3 1 1 4 4 4 1 Homeodomain-like domain HTH_23 PF13384.1 EIE84773.1 - 0.00078 19.0 0.1 0.03 13.9 0.0 2.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.1 EIE84773.1 - 0.0018 18.2 0.0 0.0075 16.2 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_21 PF13276.1 EIE84773.1 - 0.002 18.0 0.1 0.13 12.2 0.0 2.8 3 0 0 3 3 3 1 HTH-like domain rve PF00665.21 EIE84773.1 - 0.0035 17.4 0.0 0.01 15.9 0.0 2.0 2 1 0 2 2 2 1 Integrase core domain HTH_7 PF02796.10 EIE84773.1 - 0.0089 15.8 1.9 0.22 11.4 0.1 2.8 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase Sigma70_r4_2 PF08281.7 EIE84773.1 - 0.0098 15.3 0.7 0.39 10.2 0.0 3.2 4 0 0 4 4 4 1 Sigma-70, region 4 HTH_Tnp_4 PF13613.1 EIE84773.1 - 0.016 14.7 0.1 0.041 13.4 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease CPSase_L_D3 PF02787.14 EIE84773.1 - 0.11 12.2 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain LacI PF00356.16 EIE84773.1 - 0.33 10.6 1.8 2.8 7.6 0.2 2.5 3 0 0 3 3 3 0 Bacterial regulatory proteins, lacI family HTH_Tnp_ISL3 PF13542.1 EIE84773.1 - 1.1 8.5 3.3 15 4.8 0.1 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 Chromo PF00385.19 EIE84774.1 - 9.8e-09 34.7 0.3 1.7e-08 33.9 0.2 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DDE_3 PF13358.1 EIE84775.1 - 1.6e-14 53.8 0.5 2.2e-14 53.4 0.4 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE84775.1 - 0.0054 16.8 0.0 0.011 15.8 0.0 1.6 1 1 0 1 1 1 1 Integrase core domain Myb_DNA-bind_5 PF13873.1 EIE84775.1 - 0.027 14.3 0.6 3.8 7.4 0.1 2.5 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain DUF1033 PF06279.6 EIE84775.1 - 0.038 13.7 0.3 0.074 12.8 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1033) HMG_box PF00505.14 EIE84775.1 - 0.14 12.4 0.9 0.23 11.7 0.3 1.8 2 1 0 2 2 2 0 HMG (high mobility group) box rve PF00665.21 EIE84776.1 - 7.3e-05 22.8 0.0 0.00014 21.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.5 EIE84776.1 - 0.00048 19.4 0.4 0.00097 18.4 0.3 1.5 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger TRF PF08558.5 EIE84776.1 - 0.083 12.2 0.5 0.14 11.4 0.1 1.4 1 1 0 1 1 1 0 Telomere repeat binding factor (TRF) NblA PF04485.7 EIE84776.1 - 0.11 12.3 0.6 0.11 12.3 0.4 2.2 3 1 0 3 3 3 0 Phycobilisome degradation protein nblA DDE_3 PF13358.1 EIE84777.1 - 1.6e-14 53.8 0.5 2.2e-14 53.4 0.4 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE84777.1 - 0.0054 16.8 0.0 0.011 15.8 0.0 1.6 1 1 0 1 1 1 1 Integrase core domain Myb_DNA-bind_5 PF13873.1 EIE84777.1 - 0.027 14.3 0.6 3.8 7.4 0.1 2.5 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain DUF1033 PF06279.6 EIE84777.1 - 0.038 13.7 0.3 0.074 12.8 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1033) HMG_box PF00505.14 EIE84777.1 - 0.14 12.4 0.9 0.23 11.7 0.3 1.8 2 1 0 2 2 2 0 HMG (high mobility group) box RVT_1 PF00078.22 EIE84778.1 - 8.2e-13 48.1 0.2 1.1e-08 34.6 0.0 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease PF09668.5 EIE84778.1 - 1.8e-10 40.4 0.0 3.3e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 EIE84778.1 - 1.6e-08 34.8 0.0 3.4e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 EIE84778.1 - 1.2e-06 28.3 0.0 3.4e-06 26.8 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.6 EIE84778.1 - 4e-06 26.8 0.0 7.5e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EIE84778.1 - 3.2e-05 23.6 0.1 6e-05 22.7 0.1 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1759 PF03564.10 EIE84779.1 - 0.0024 17.7 0.2 0.0067 16.2 0.2 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) Leader_Erm PF08253.6 EIE84781.1 - 0.33 10.4 0.3 0.33 10.4 0.2 2.1 2 0 0 2 2 2 0 Erm Leader peptide RVT_1 PF00078.22 EIE84783.1 - 4.3e-17 62.1 0.0 8.6e-17 61.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EIE84783.1 - 4.5e-14 52.5 0.0 1.6e-13 50.8 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.19 EIE84783.1 - 6.6e-11 41.7 0.6 1.8e-10 40.3 0.4 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 EIE84783.1 - 0.00025 20.3 0.1 0.00073 18.9 0.1 1.9 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Chromo PF00385.19 EIE84785.1 - 3.9e-11 42.4 0.4 7.7e-11 41.5 0.3 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain S1_2 PF13509.1 EIE84785.1 - 0.07 13.0 0.1 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 S1 domain RVT_1 PF00078.22 EIE84786.1 - 2.4e-11 43.3 0.3 4.5e-11 42.5 0.2 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.12 EIE84786.1 - 0.00061 19.8 0.1 0.0022 17.9 0.1 1.9 1 0 0 1 1 1 1 Retrotransposon gag protein Sed5p PF11416.3 EIE84786.1 - 1.6 8.2 5.0 3.7 7.0 1.2 2.8 2 0 0 2 2 2 0 Integral membrane protein Sed5p FlgM PF04316.8 EIE84787.1 - 0.11 12.4 5.0 0.17 11.8 3.5 1.3 1 0 0 1 1 1 0 Anti-sigma-28 factor, FlgM OCIA PF07051.6 EIE84787.1 - 0.29 10.5 2.5 0.34 10.3 1.7 1.1 1 0 0 1 1 1 0 Ovarian carcinoma immunoreactive antigen (OCIA) PHD_3 PF13922.1 EIE84787.1 - 2 8.7 7.3 2.3 8.5 5.1 1.2 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx HTH_23 PF13384.1 EIE84788.1 - 0.015 14.9 0.1 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain HTH_38 PF13936.1 EIE84788.1 - 0.097 12.2 0.1 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain DUF3420 PF11900.3 EIE84788.1 - 0.17 12.0 0.5 0.23 11.5 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3420) DDE_3 PF13358.1 EIE84789.1 - 8.2e-21 74.2 0.0 1.5e-20 73.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE84789.1 - 7.1e-16 58.0 1.3 2.8e-15 56.1 0.3 2.4 3 0 0 3 3 2 1 Transposase HTH_29 PF13551.1 EIE84789.1 - 6.1e-06 26.3 0.2 1.9e-05 24.7 0.1 1.9 2 0 0 2 2 1 1 Winged helix-turn helix HTH_38 PF13936.1 EIE84789.1 - 3.7e-05 23.1 0.0 0.0001 21.7 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_32 PF13565.1 EIE84789.1 - 0.00016 22.3 3.3 0.019 15.7 0.0 3.7 3 1 1 4 4 3 1 Homeodomain-like domain HTH_23 PF13384.1 EIE84789.1 - 0.00095 18.7 0.0 0.036 13.7 0.0 2.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_21 PF13276.1 EIE84789.1 - 0.0018 18.2 0.1 0.13 12.2 0.0 2.8 3 0 0 3 3 3 1 HTH-like domain HTH_28 PF13518.1 EIE84789.1 - 0.0022 17.9 0.0 0.01 15.8 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.7 EIE84789.1 - 0.004 16.5 0.4 0.2 11.1 0.0 3.2 4 0 0 4 4 4 1 Sigma-70, region 4 rve PF00665.21 EIE84789.1 - 0.0045 17.0 0.0 0.014 15.4 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain HTH_Tnp_4 PF13613.1 EIE84789.1 - 0.012 15.1 0.1 0.03 13.8 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_7 PF02796.10 EIE84789.1 - 0.016 15.0 0.8 0.89 9.4 0.0 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain of resolvase LacI PF00356.16 EIE84789.1 - 0.038 13.6 1.4 2.8 7.6 0.2 2.7 3 0 0 3 3 3 0 Bacterial regulatory proteins, lacI family DUF2857 PF11198.3 EIE84789.1 - 0.058 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2857) UPF0122 PF04297.9 EIE84789.1 - 0.088 12.8 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like CPSase_L_D3 PF02787.14 EIE84789.1 - 0.097 12.4 0.0 0.24 11.1 0.0 1.7 2 0 0 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain Sigma70_r4 PF04545.11 EIE84789.1 - 0.12 11.7 0.2 0.96 8.8 0.0 2.6 4 0 0 4 4 4 0 Sigma-70, region 4 HTH_Tnp_ISL3 PF13542.1 EIE84789.1 - 0.35 10.0 2.8 15 4.8 0.1 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 zf-CCHC PF00098.18 EIE84790.1 - 1.4e-11 43.6 6.4 3.4e-05 23.5 0.2 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 EIE84790.1 - 0.00015 21.3 5.9 0.0087 15.7 0.4 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.1 EIE84790.1 - 0.0019 17.6 4.7 0.028 13.9 1.2 2.4 1 1 1 2 2 2 1 Zinc knuckle zf-CCHC_6 PF15288.1 EIE84790.1 - 0.049 13.3 1.9 0.049 13.3 1.3 2.2 1 1 1 2 2 2 0 Zinc knuckle zinc-ribbons_6 PF07191.7 EIE84790.1 - 0.12 12.2 3.0 0.26 11.1 2.1 1.6 1 0 0 1 1 1 0 zinc-ribbons Zn_ribbon_2 PF12674.2 EIE84790.1 - 0.26 11.6 2.1 0.8 10.0 1.3 1.9 1 1 0 1 1 1 0 Putative zinc ribbon domain zf-CCHC_3 PF13917.1 EIE84790.1 - 0.76 9.5 7.0 0.61 9.8 0.4 2.6 1 1 1 2 2 2 0 Zinc knuckle EHN PF06441.7 EIE84791.1 - 2.2e-29 101.6 1.6 4.9e-29 100.5 1.1 1.6 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EIE84791.1 - 5.6e-11 42.7 0.0 1e-10 41.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIE84791.1 - 2.4e-09 37.1 0.0 4.3e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Lactamase_B_2 PF12706.2 EIE84792.1 - 1.3e-09 37.8 0.0 1.6e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EIE84792.1 - 4e-05 23.3 0.2 6.2e-05 22.7 0.1 1.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.1 EIE84792.1 - 0.14 11.8 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Beta-lactamase superfamily domain DUF2146 PF10220.4 EIE84793.1 - 1.6e-64 218.4 8.5 1.8e-28 99.0 2.9 3.0 3 0 0 3 3 3 3 Uncharacterized conserved protein (DUF2146) RabGAP-TBC PF00566.13 EIE84794.1 - 4.7e-06 26.2 0.2 4.7e-06 26.2 0.1 2.4 2 1 0 3 3 3 1 Rab-GTPase-TBC domain PPR_2 PF13041.1 EIE84795.1 - 6.3e-30 102.9 1.6 3.8e-09 36.3 0.0 6.9 5 2 2 7 7 7 6 PPR repeat family PPR_1 PF12854.2 EIE84795.1 - 4.5e-15 54.8 3.3 4.7e-06 25.9 0.0 5.1 5 0 0 5 5 5 3 PPR repeat PPR_3 PF13812.1 EIE84795.1 - 2.3e-13 49.2 1.6 0.0011 19.0 0.0 6.1 7 2 1 8 8 8 2 Pentatricopeptide repeat domain PPR PF01535.15 EIE84795.1 - 1.9e-10 39.9 0.3 0.00021 21.0 0.0 5.9 6 0 0 6 6 6 1 PPR repeat RPM2 PF08579.6 EIE84795.1 - 0.00056 20.0 4.9 0.0039 17.3 0.2 3.5 2 2 2 4 4 4 1 Mitochondrial ribonuclease P subunit (RPM2) Rep_fac_C PF08542.6 EIE84795.1 - 0.021 14.8 0.2 0.2 11.6 0.0 2.7 3 1 1 4 4 4 0 Replication factor C C-terminal domain TPR_19 PF14559.1 EIE84795.1 - 0.11 12.8 0.0 0.35 11.2 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Pas_Saposin PF09016.5 EIE84795.1 - 0.15 12.0 1.2 2 8.4 0.4 2.5 2 0 0 2 2 2 0 Pas factor saposin fold RNA_pol_Rpc82 PF05645.8 EIE84796.1 - 9.9e-14 51.4 0.3 3.6e-13 49.6 0.1 2.1 1 1 0 1 1 1 1 RNA polymerase III subunit RPC82 TFIIE_alpha PF02002.12 EIE84796.1 - 5.5e-05 22.6 0.9 5.5e-05 22.6 0.6 2.2 2 0 0 2 2 2 1 TFIIE alpha subunit TrmB PF01978.14 EIE84796.1 - 0.0016 18.1 1.0 0.13 11.9 0.0 3.2 3 0 0 3 3 3 1 Sugar-specific transcriptional regulator TrmB HTH_9 PF08221.6 EIE84796.1 - 0.018 14.9 0.1 0.058 13.2 0.0 1.8 2 0 0 2 2 2 0 RNA polymerase III subunit RPC82 helix-turn-helix domain DUF4226 PF10774.4 EIE84796.1 - 0.34 10.9 4.3 0.21 11.6 0.7 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4226) RVT_1 PF00078.22 EIE84797.1 - 1.2e-25 90.1 0.0 2.6e-25 89.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1668 PF07893.8 EIE84798.1 - 0.037 13.1 0.0 0.052 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1668) HAUS4 PF14735.1 EIE84798.1 - 0.078 12.2 0.1 0.24 10.6 0.0 1.8 2 1 0 2 2 2 0 HAUS augmin-like complex subunit 4 AAA PF00004.24 EIE84800.1 - 4.6e-42 143.3 0.0 8.8e-42 142.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EIE84800.1 - 3.5e-06 27.0 0.0 6.9e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EIE84800.1 - 6e-06 26.4 0.1 0.00073 19.6 0.1 2.4 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 EIE84800.1 - 1.7e-05 23.8 0.0 2.9e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 EIE84800.1 - 3.2e-05 23.6 0.4 0.00042 20.0 0.2 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EIE84800.1 - 0.00013 22.0 0.0 0.00076 19.5 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 EIE84800.1 - 0.00044 19.3 0.0 0.0008 18.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EIE84800.1 - 0.0011 18.8 0.0 0.0021 17.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 EIE84800.1 - 0.0029 17.2 0.0 0.0087 15.6 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EIE84800.1 - 0.0047 17.2 0.1 0.02 15.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EIE84800.1 - 0.005 17.6 0.7 0.0095 16.7 0.2 2.0 2 1 0 2 2 1 1 AAA domain AAA_19 PF13245.1 EIE84800.1 - 0.0064 16.2 0.4 0.014 15.1 0.2 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 EIE84800.1 - 0.0065 16.3 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 EIE84800.1 - 0.0073 15.4 0.7 0.18 10.9 0.1 2.7 2 1 1 3 3 3 1 KaiC IstB_IS21 PF01695.12 EIE84800.1 - 0.011 15.1 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Zeta_toxin PF06414.7 EIE84800.1 - 0.016 14.3 0.0 0.027 13.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin NB-ARC PF00931.17 EIE84800.1 - 0.016 14.0 0.0 0.054 12.3 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain NACHT PF05729.7 EIE84800.1 - 0.024 14.3 0.1 0.36 10.4 0.1 2.3 1 1 0 2 2 2 0 NACHT domain AAA_28 PF13521.1 EIE84800.1 - 0.026 14.4 1.8 0.063 13.2 0.0 2.4 3 0 0 3 3 2 0 AAA domain TIP49 PF06068.8 EIE84800.1 - 0.032 12.9 0.0 0.051 12.2 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus AAA_25 PF13481.1 EIE84800.1 - 0.045 13.1 0.9 1.7 7.9 0.2 2.6 1 1 1 2 2 2 0 AAA domain DUF2075 PF09848.4 EIE84800.1 - 0.062 12.2 0.0 0.085 11.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.17 EIE84800.1 - 0.082 13.0 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.16 EIE84800.1 - 0.098 11.8 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.13 EIE84800.1 - 0.1 12.0 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.1 EIE84800.1 - 0.11 12.0 0.2 0.31 10.5 0.2 1.7 1 0 0 1 1 1 0 AAA domain Ank PF00023.25 EIE84801.1 - 3.6e-11 42.2 0.3 1.3e-07 31.0 0.0 3.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 EIE84801.1 - 3e-10 40.0 0.4 0.00011 22.2 0.0 3.2 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EIE84801.1 - 8.8e-10 38.8 0.1 0.11 13.0 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 EIE84801.1 - 3.3e-09 36.9 0.0 5e-08 33.1 0.0 2.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EIE84801.1 - 1.6e-07 30.9 0.0 0.00018 21.4 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat DUF1356 PF07092.7 EIE84802.1 - 0.072 12.2 0.3 0.12 11.6 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1356) Arrestin_C PF02752.17 EIE84803.1 - 1.7e-18 67.0 0.0 2.3e-15 56.8 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EIE84803.1 - 2e-10 40.7 0.0 5e-10 39.3 0.0 1.6 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 EIE84803.1 - 0.00021 20.8 0.0 0.00039 19.9 0.0 1.4 1 0 0 1 1 1 1 Arrestin_N terminal like DUF3425 PF11905.3 EIE84808.1 - 2.6e-13 50.0 6.1 2.3e-11 43.7 4.2 2.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 EIE84808.1 - 1.8e-05 24.5 9.0 4.1e-05 23.4 6.2 1.5 1 0 0 1 1 1 1 bZIP transcription factor Astro_capsid PF03115.9 EIE84808.1 - 0.29 9.3 3.6 0.41 8.8 2.5 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor DDE_3 PF13358.1 EIE84810.1 - 2.8e-06 27.1 0.0 8.5e-06 25.5 0.0 1.8 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 EIE84810.1 - 6.8e-06 26.2 0.0 1.3e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.1 EIE84810.1 - 0.0087 16.0 0.4 0.022 14.7 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain DUF1804 PF08822.6 EIE84810.1 - 0.01 15.5 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1804) Cobl PF09469.5 EIE84812.1 - 3.8 7.5 6.7 2.7 8.0 0.7 3.0 3 0 0 3 3 3 0 Cordon-bleu ubiquitin-like domain GxGYxYP PF14323.1 EIE84813.1 - 0.086 11.5 0.1 0.084 11.5 0.1 1.0 1 0 0 1 1 1 0 GxGYxY sequence motif in domain of unknown function GATA PF00320.22 EIE84816.1 - 0.0047 16.2 10.7 0.0047 16.2 7.4 3.1 2 1 0 2 2 2 1 GATA zinc finger zf-C3HC4_3 PF13920.1 EIE84816.1 - 0.12 12.1 13.1 0.3 10.7 2.4 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DZR PF12773.2 EIE84816.1 - 1.2 9.0 9.9 0.84 9.5 0.1 2.6 2 1 0 2 2 2 0 Double zinc ribbon CLASP_N PF12348.3 EIE84817.1 - 9.2e-21 74.2 14.8 1.6e-08 34.1 0.0 6.5 6 1 0 7 7 7 3 CLASP N terminal HEAT_2 PF13646.1 EIE84817.1 - 1.7e-14 53.8 0.9 0.61 10.4 0.0 7.9 6 1 0 6 6 6 3 HEAT repeats HEAT PF02985.17 EIE84817.1 - 2.7e-08 33.2 16.7 0.048 13.7 0.0 11.1 14 0 0 14 14 14 2 HEAT repeat Vac14_Fab1_bd PF12755.2 EIE84817.1 - 0.01 16.1 0.0 35 4.8 0.0 4.7 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 EIE84817.1 - 0.053 13.3 4.7 3.2 7.5 0.0 5.1 4 1 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 EIE84817.1 - 0.059 13.8 5.5 87 3.7 0.2 6.2 6 0 0 6 6 6 0 HEAT-like repeat CaKB PF03185.10 EIE84819.1 - 0.076 12.3 1.6 0.1 11.9 1.1 1.3 1 0 0 1 1 1 0 Calcium-activated potassium channel, beta subunit Dicty_REP PF05086.7 EIE84819.1 - 2.5 5.7 7.7 3.2 5.3 5.3 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Aa_trans PF01490.13 EIE84820.1 - 6e-13 48.0 15.6 4.6e-09 35.2 3.6 2.0 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EIE84820.1 - 0.0081 15.0 11.1 0.016 14.0 7.6 1.5 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family GrpE PF01025.14 EIE84821.1 - 1e-47 161.7 5.8 1.4e-47 161.3 4.0 1.2 1 0 0 1 1 1 1 GrpE HlyD_2 PF12700.2 EIE84821.1 - 0.022 13.9 2.6 0.026 13.6 1.8 1.3 1 0 0 1 1 1 0 HlyD family secretion protein YjcZ PF13990.1 EIE84821.1 - 0.3 10.1 2.6 0.36 9.9 1.2 1.5 1 1 0 1 1 1 0 YjcZ-like protein Cep57_CLD_2 PF14197.1 EIE84821.1 - 0.56 10.1 6.9 2 8.4 0.9 2.6 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 Baculo_PEP_C PF04513.7 EIE84821.1 - 0.99 9.2 5.6 2.7 7.8 3.9 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Mit_KHE1 PF10173.4 EIE84821.1 - 1.4 8.6 4.5 8.3 6.2 3.1 1.9 1 1 0 1 1 1 0 Mitochondrial K+-H+ exchange-related DUF4065 PF13274.1 EIE84821.1 - 3 8.6 5.6 55 4.5 3.9 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4065) Pkinase PF00069.20 EIE84822.1 - 9.2e-69 231.4 0.0 1.3e-68 231.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE84822.1 - 1.7e-28 99.4 0.0 2.5e-28 98.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EIE84822.1 - 4.8e-05 22.5 0.0 0.00015 20.9 0.0 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIE84822.1 - 0.00058 19.6 0.0 0.00092 19.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EIE84822.1 - 0.012 14.5 0.0 0.038 12.9 0.0 1.6 1 1 0 2 2 2 0 Kinase-like RIO1 PF01163.17 EIE84822.1 - 0.045 13.1 0.0 0.081 12.2 0.0 1.4 1 0 0 1 1 1 0 RIO1 family UPF0113 PF03657.8 EIE84824.1 - 6.3e-10 38.9 0.0 7.5e-10 38.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) AMNp_N PF10423.4 EIE84824.1 - 0.14 11.6 0.0 0.31 10.6 0.0 1.7 1 1 1 2 2 2 0 Bacterial AMP nucleoside phosphorylase N-terminus SH3BGR PF04908.10 EIE84825.1 - 1.8e-12 47.0 4.7 2.3e-12 46.7 0.3 3.0 2 0 0 2 2 2 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.19 EIE84825.1 - 6e-05 22.9 0.0 0.00027 20.8 0.0 2.3 1 0 0 1 1 1 1 Glutaredoxin TBPIP PF07106.8 EIE84826.1 - 4.3e-37 127.2 14.8 6e-37 126.7 10.3 1.2 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) PX PF00787.19 EIE84826.1 - 0.032 14.0 3.3 0.17 11.7 2.1 2.0 1 1 1 2 2 2 0 PX domain TraF PF13728.1 EIE84826.1 - 0.27 10.6 4.1 0.31 10.5 2.2 1.5 1 1 0 1 1 1 0 F plasmid transfer operon protein DivIC PF04977.10 EIE84826.1 - 0.43 10.0 10.8 0.28 10.7 0.6 3.3 1 1 2 3 3 3 0 Septum formation initiator DUF3452 PF11934.3 EIE84826.1 - 2 7.7 10.0 1.9 7.8 4.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3452) DUF904 PF06005.7 EIE84826.1 - 2.3 8.5 13.4 9.6e+02 0.1 9.3 3.4 1 1 0 1 1 1 0 Protein of unknown function (DUF904) Ofd1_CTDD PF10637.4 EIE84827.1 - 2.8e-75 252.8 0.0 1.9e-68 230.4 0.0 2.5 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 EIE84827.1 - 3.8e-16 59.4 0.0 7.7e-16 58.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_5 PF13759.1 EIE84827.1 - 0.1 12.8 0.0 0.26 11.5 0.0 1.7 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase rve PF00665.21 EIE84828.1 - 1.4e-23 83.2 0.0 3.2e-23 82.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 EIE84828.1 - 6.2e-12 44.9 0.2 1.2e-11 44.0 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 EIE84828.1 - 0.0029 16.9 0.1 0.006 15.9 0.0 1.6 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger RVT_1 PF00078.22 EIE84829.1 - 5e-36 124.0 0.0 1.1e-35 122.9 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 EIE84830.1 - 7e-17 61.4 0.0 3e-16 59.4 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.18 EIE84830.1 - 0.0008 19.2 18.1 0.0078 16.1 1.0 3.6 3 0 0 3 3 3 2 Zinc knuckle Asp_protease_2 PF13650.1 EIE84830.1 - 0.00081 19.8 0.9 0.0064 16.9 0.0 2.9 3 0 0 3 3 3 1 Aspartyl protease DDE_3 PF13358.1 EIE84832.1 - 1.6e-14 53.8 0.1 3.7e-14 52.7 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE84832.1 - 5.2e-10 39.2 0.9 1.3e-09 38.0 0.6 1.7 1 0 0 1 1 1 1 Transposase HTH_Tnp_4 PF13613.1 EIE84832.1 - 0.082 12.4 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease DDE_3 PF13358.1 EIE84834.1 - 9.5e-20 70.8 0.0 1.9e-19 69.8 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE84834.1 - 1.2e-13 50.8 1.4 3.8e-13 49.3 0.2 2.3 2 0 0 2 2 2 1 Transposase HTH_38 PF13936.1 EIE84834.1 - 1.1e-05 24.8 0.1 3.3e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_29 PF13551.1 EIE84834.1 - 1.6e-05 24.9 0.3 4.5e-05 23.5 0.2 1.8 2 0 0 2 2 1 1 Winged helix-turn helix HTH_23 PF13384.1 EIE84834.1 - 7.7e-05 22.2 0.0 0.0029 17.1 0.0 2.7 2 0 0 2 2 2 1 Homeodomain-like domain Sigma70_r4_2 PF08281.7 EIE84834.1 - 0.00048 19.5 0.1 0.024 14.0 0.0 3.0 3 0 0 3 3 3 1 Sigma-70, region 4 HTH_32 PF13565.1 EIE84834.1 - 0.00088 20.0 1.7 0.08 13.7 0.1 3.2 4 0 0 4 4 3 1 Homeodomain-like domain HTH_21 PF13276.1 EIE84834.1 - 0.0014 18.6 0.1 0.13 12.2 0.0 2.9 3 0 0 3 3 3 1 HTH-like domain rve PF00665.21 EIE84834.1 - 0.0053 16.8 0.0 0.019 15.0 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain HTH_28 PF13518.1 EIE84834.1 - 0.0073 16.2 0.1 0.032 14.2 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain LacI PF00356.16 EIE84834.1 - 0.017 14.6 1.7 2.8 7.6 0.2 2.7 3 0 0 3 3 3 0 Bacterial regulatory proteins, lacI family HTH_Tnp_4 PF13613.1 EIE84834.1 - 0.022 14.2 0.1 0.057 12.9 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_7 PF02796.10 EIE84834.1 - 0.053 13.3 1.5 0.1 12.4 0.0 2.2 3 0 0 3 3 3 0 Helix-turn-helix domain of resolvase CPSase_L_D3 PF02787.14 EIE84834.1 - 0.059 13.1 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain HTH_36 PF13730.1 EIE84834.1 - 0.072 13.2 0.4 4.1 7.6 0.0 3.0 3 0 0 3 3 2 0 Helix-turn-helix domain Sigma70_r4 PF04545.11 EIE84834.1 - 0.097 11.9 0.2 0.79 9.0 0.0 2.6 4 0 0 4 4 4 0 Sigma-70, region 4 HTH_Tnp_ISL3 PF13542.1 EIE84834.1 - 0.15 11.2 2.5 8.4 5.6 0.0 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 HTH_17 PF12728.2 EIE84834.1 - 0.18 12.0 2.9 11 6.3 0.1 3.2 3 0 0 3 3 3 0 Helix-turn-helix domain Leader_Erm PF08253.6 EIE84835.1 - 0.33 10.4 0.3 0.33 10.4 0.2 2.1 2 0 0 2 2 2 0 Erm Leader peptide Sigma70_r1_2 PF00140.15 EIE84836.1 - 0.0013 18.3 0.1 0.0024 17.5 0.1 1.4 1 0 0 1 1 1 1 Sigma-70 factor, region 1.2 Trp_repressor PF01371.14 EIE84836.1 - 0.052 13.4 0.1 0.095 12.6 0.1 1.5 1 0 0 1 1 1 0 Trp repressor protein DUF4236 PF14020.1 EIE84836.1 - 0.057 13.5 0.0 0.21 11.7 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF4236) rve PF00665.21 EIE84837.1 - 1.7e-24 86.1 0.0 5.6e-24 84.5 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE84837.1 - 6.7e-17 61.5 0.0 1.3e-16 60.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE84837.1 - 9e-11 41.2 0.6 2.6e-10 39.8 0.4 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 EIE84837.1 - 0.00036 19.8 0.1 0.001 18.4 0.1 1.9 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger UBN2_2 PF14227.1 EIE84837.1 - 0.017 14.6 1.1 0.33 10.5 0.0 2.8 3 0 0 3 3 3 0 gag-polypeptide of LTR copia-type rve_3 PF13683.1 EIE84837.1 - 0.026 14.0 0.0 0.087 12.3 0.0 1.9 1 0 0 1 1 1 0 Integrase core domain UBN2 PF14223.1 EIE84837.1 - 0.062 13.0 0.6 0.16 11.7 0.1 1.9 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type DUF3659 PF12396.3 EIE84838.1 - 3.3e-31 106.7 15.2 3.4e-17 61.8 3.4 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF3659) DUF1993 PF09351.5 EIE84838.1 - 0.067 13.1 1.2 0.19 11.6 0.8 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1993) RecQ5 PF06959.6 EIE84839.1 - 0.95 9.0 11.4 0.74 9.4 7.1 1.3 1 1 0 1 1 1 0 RecQ helicase protein-like 5 (RecQ5) TFIIF_alpha PF05793.7 EIE84839.1 - 0.97 7.7 19.5 1.2 7.4 13.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RP-C_C PF11800.3 EIE84839.1 - 1.7 8.2 5.0 1.9 8.1 3.5 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region API5 PF05918.6 EIE84839.1 - 2.4 6.5 7.5 2.6 6.4 5.2 1.0 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) DUF3807 PF12720.2 EIE84839.1 - 3.4 7.7 14.7 4.4 7.4 10.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) FLO_LFY PF01698.11 EIE84839.1 - 8.5 5.1 12.1 11 4.8 8.4 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein MIP-T3 PF10243.4 EIE84840.1 - 8.2 4.7 37.0 9.4 4.5 25.6 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Tub PF01167.13 EIE84843.1 - 6.6e-45 153.0 0.1 7.1e-45 152.9 0.1 1.0 1 0 0 1 1 1 1 Tub family DUF3527 PF12043.3 EIE84843.1 - 0.036 13.6 0.2 0.055 13.0 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3527) Tub PF01167.13 EIE84844.1 - 0.0007 18.6 0.0 0.0008 18.4 0.0 1.1 1 0 0 1 1 1 1 Tub family Kinesin PF00225.18 EIE84845.1 - 1.7e-103 345.8 2.1 1.7e-103 345.8 1.5 3.9 3 1 0 3 3 3 1 Kinesin motor domain Filament PF00038.16 EIE84845.1 - 0.0053 16.2 19.9 0.0053 16.2 13.8 8.8 3 1 2 6 6 6 3 Intermediate filament protein DUF2431 PF10354.4 EIE84846.1 - 6.6e-51 172.5 1.2 8.5e-51 172.2 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF2431) MTS PF05175.9 EIE84846.1 - 0.017 14.4 0.3 0.037 13.3 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_26 PF13659.1 EIE84846.1 - 0.028 14.4 0.0 0.042 13.8 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain DUF2681 PF10883.3 EIE84846.1 - 2.4 8.4 7.7 6.2 7.0 5.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Kinesin PF00225.18 EIE84847.1 - 1.9e-86 289.8 5.4 1.9e-86 289.8 3.7 4.4 4 2 0 4 4 4 1 Kinesin motor domain Arch_ATPase PF01637.13 EIE84847.1 - 0.00055 19.6 0.0 0.00055 19.6 0.0 4.7 5 1 1 6 6 6 1 Archaeal ATPase DUF3840 PF12944.2 EIE84848.1 - 1.3 8.8 5.8 0.43 10.4 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3840) zf-CHC2 PF01807.15 EIE84849.1 - 0.028 13.9 0.2 0.072 12.6 0.1 1.7 1 0 0 1 1 1 0 CHC2 zinc finger zf-CCHC PF00098.18 EIE84849.1 - 0.028 14.3 5.0 0.045 13.6 3.5 1.3 1 0 0 1 1 1 0 Zinc knuckle Polysacc_deac_1 PF01522.16 EIE84850.1 - 1.7e-25 89.0 0.0 2.8e-25 88.3 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase SQS_PSY PF00494.14 EIE84851.1 - 3e-38 131.6 0.0 3.3e-38 131.5 0.0 1.0 1 0 0 1 1 1 1 Squalene/phytoene synthase RNA_pol_Rpb4 PF03874.11 EIE84852.1 - 2.4e-26 92.0 7.5 2.8e-26 91.8 5.2 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 Hormone_3 PF00159.13 EIE84852.1 - 0.02 14.9 0.1 0.12 12.4 0.0 2.2 1 1 1 2 2 2 0 Pancreatic hormone peptide DUF964 PF06133.6 EIE84852.1 - 0.16 11.9 4.3 0.24 11.4 1.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF964) LEA_2 PF03168.8 EIE84853.1 - 0.00013 22.3 0.4 0.00019 21.7 0.3 1.3 1 0 0 1 1 1 1 Late embryogenesis abundant protein DUF2897 PF11446.3 EIE84853.1 - 8.9 6.2 6.6 16 5.4 4.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) SLAC1 PF03595.12 EIE84854.1 - 5.4e-78 261.9 37.7 2.8e-56 190.5 16.8 2.0 1 1 1 2 2 2 2 Voltage-dependent anion channel PH PF00169.24 EIE84855.1 - 1.7e-21 76.3 0.7 1.7e-21 76.3 0.5 2.3 2 0 0 2 2 2 1 PH domain SAM_2 PF07647.12 EIE84855.1 - 2.5e-14 52.8 0.1 5.8e-14 51.6 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_1 PF00018.23 EIE84855.1 - 9e-12 44.2 0.2 2.6e-11 42.7 0.1 1.8 1 0 0 1 1 1 1 SH3 domain SAM_1 PF00536.25 EIE84855.1 - 2e-11 43.9 0.1 4.2e-11 42.8 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.1 EIE84855.1 - 7e-11 41.5 0.0 1.7e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EIE84855.1 - 1.4e-07 30.8 0.1 3.1e-07 29.7 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain PH_11 PF15413.1 EIE84855.1 - 1.2e-05 25.4 11.2 2.1e-05 24.7 3.6 3.2 2 1 0 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.1 EIE84855.1 - 0.0018 18.0 0.7 0.0065 16.3 0.5 1.9 1 0 0 1 1 1 1 PH domain CH PF00307.26 EIE84855.1 - 0.0035 17.3 0.0 0.01 15.8 0.0 1.8 1 0 0 1 1 1 1 Calponin homology (CH) domain PH_8 PF15409.1 EIE84855.1 - 0.0097 15.9 2.0 0.04 13.9 1.4 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain Ste50p-SAM PF09235.5 EIE84855.1 - 0.0099 15.8 0.6 0.024 14.6 0.4 1.6 1 0 0 1 1 1 1 Ste50p, sterile alpha motif T2SM PF04612.7 EIE84855.1 - 0.064 13.0 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M F-box-like PF12937.2 EIE84856.1 - 2.3e-11 43.2 1.9 4.7e-11 42.2 0.8 2.0 2 0 0 2 2 2 1 F-box-like WD40 PF00400.27 EIE84856.1 - 1.2e-08 34.5 7.9 4e-05 23.3 0.1 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat F-box PF00646.28 EIE84856.1 - 9.4e-08 31.5 0.3 2.1e-07 30.4 0.2 1.5 1 0 0 1 1 1 1 F-box domain UPF0542 PF15086.1 EIE84856.1 - 0.03 14.0 0.1 0.18 11.5 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 NifU PF01106.12 EIE84857.1 - 6.7e-24 83.4 0.1 9.8e-24 82.9 0.1 1.2 1 0 0 1 1 1 1 NifU-like domain Nfu_N PF08712.6 EIE84857.1 - 1.8e-19 69.1 0.0 7.5e-19 67.1 0.0 1.9 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal PH PF00169.24 EIE84860.1 - 4.7e-13 49.2 2.9 1.5e-12 47.6 2.0 2.0 1 1 0 1 1 1 1 PH domain PH_11 PF15413.1 EIE84860.1 - 0.00016 21.9 3.2 0.0042 17.3 1.8 2.9 2 1 0 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.1 EIE84860.1 - 0.00044 20.0 3.4 0.0012 18.7 2.3 1.7 2 0 0 2 2 2 1 PH domain PH_8 PF15409.1 EIE84860.1 - 0.02 14.9 1.8 0.039 14.0 1.2 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain PBP1_TM PF14812.1 EIE84860.1 - 0.031 14.5 1.2 0.031 14.5 0.8 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PH_9 PF15410.1 EIE84860.1 - 0.091 12.9 4.7 1.2 9.3 2.6 2.6 2 1 0 2 2 2 0 Pleckstrin homology domain DEAD PF00270.24 EIE84861.1 - 3.9e-39 133.8 0.0 2.1e-38 131.4 0.0 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIE84861.1 - 5.3e-22 77.4 0.0 3e-21 75.0 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIE84861.1 - 3.9e-10 39.8 0.0 7.9e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EIE84861.1 - 0.00085 19.4 0.2 0.3 11.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain SNF2_N PF00176.18 EIE84861.1 - 0.0079 15.0 0.0 0.013 14.3 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Flavi_DEAD PF07652.9 EIE84861.1 - 0.034 13.8 0.0 0.065 12.9 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_19 PF13245.1 EIE84861.1 - 0.078 12.7 0.1 0.2 11.4 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain Na_Ca_ex PF01699.19 EIE84862.1 - 1.7e-25 89.2 19.6 3.7e-14 52.5 0.6 2.9 3 0 0 3 3 3 2 Sodium/calcium exchanger protein HAD_2 PF13419.1 EIE84864.1 - 1.2e-17 64.6 0.0 1.4e-17 64.4 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EIE84864.1 - 3.2e-06 27.6 0.0 3.7e-06 27.4 0.0 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EIE84864.1 - 0.0031 17.1 0.0 0.0055 16.3 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like DUF3895 PF13034.1 EIE84864.1 - 0.05 13.0 0.0 0.081 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3895) HAD PF12710.2 EIE84864.1 - 0.11 12.6 0.0 0.12 12.5 0.0 1.1 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DEAD PF00270.24 EIE84865.1 - 2.6e-33 114.8 0.5 2.4e-32 111.7 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIE84865.1 - 1.6e-26 91.9 0.2 3.5e-26 90.8 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 EIE84865.1 - 0.007 16.3 0.0 0.028 14.3 0.0 1.9 2 0 0 2 2 2 1 Helicase C-terminal domain AAA_30 PF13604.1 EIE84865.1 - 0.026 14.1 0.0 0.046 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF313 PF03754.8 EIE84865.1 - 0.039 13.8 0.2 2.6 7.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF313) PAT1 PF09770.4 EIE84865.1 - 0.94 7.6 20.5 1.6 6.8 14.2 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF605 PF04652.11 EIE84865.1 - 3.3 7.0 18.8 4.6 6.5 13.0 1.2 1 0 0 1 1 1 0 Vta1 like RhoGAP PF00620.22 EIE84866.1 - 2.3e-05 24.0 0.3 0.19 11.3 0.0 3.0 3 0 0 3 3 3 2 RhoGAP domain HR1 PF02185.11 EIE84866.1 - 4.3 7.1 6.9 2.4 7.9 0.6 2.6 2 0 0 2 2 2 0 Hr1 repeat Homeobox_KN PF05920.6 EIE84867.1 - 2e-18 65.7 0.4 4.5e-18 64.6 0.3 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 EIE84867.1 - 1.5e-08 34.1 0.8 1.5e-08 34.1 0.5 2.3 2 0 0 2 2 2 1 Homeobox domain DUF1053 PF06327.9 EIE84867.1 - 0.08 13.2 0.2 0.29 11.5 0.0 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1053) Kinesin PF00225.18 EIE84868.1 - 3.2e-83 279.2 7.3 3.2e-83 279.2 5.0 5.0 3 1 0 3 3 3 1 Kinesin motor domain DUF2202 PF09968.4 EIE84869.1 - 0.00025 20.7 0.9 0.00035 20.2 0.6 1.3 1 1 0 1 1 1 1 Uncharacterized protein domain (DUF2202) HTH_36 PF13730.1 EIE84869.1 - 0.082 13.0 0.2 1.3 9.2 0.2 2.2 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_Mga PF08280.6 EIE84869.1 - 0.086 12.6 0.6 8.4 6.2 0.2 2.4 1 1 1 2 2 2 0 M protein trans-acting positive regulator (MGA) HTH domain Latarcin PF10279.4 EIE84869.1 - 0.65 10.2 2.9 0.46 10.7 0.7 1.7 2 0 0 2 2 2 0 Latarcin precursor Ribosomal_L4 PF00573.17 EIE84871.1 - 2.1e-44 151.2 1.0 2.1e-44 151.2 0.7 1.7 2 0 0 2 2 2 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 EIE84871.1 - 3.7e-29 100.4 4.1 3.7e-29 100.4 2.8 2.2 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain JAB PF01398.16 EIE84872.1 - 7.9e-18 64.2 0.0 2e-17 62.9 0.0 1.6 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 EIE84872.1 - 3e-07 29.9 0.0 6.3e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain TrmE_N PF10396.4 EIE84873.1 - 7.5e-26 90.3 0.0 1.6e-25 89.2 0.0 1.6 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.18 EIE84873.1 - 2e-22 79.2 0.2 3.3e-22 78.6 0.2 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EIE84873.1 - 9.3e-09 34.7 0.2 1.8e-08 33.8 0.2 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EIE84873.1 - 1.8e-06 27.8 0.0 4.6e-06 26.5 0.0 1.8 1 1 0 1 1 1 1 Dynamin family cobW PF02492.14 EIE84873.1 - 2e-06 27.3 1.5 0.021 14.3 0.4 2.2 1 1 1 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain Miro PF08477.8 EIE84873.1 - 9.9e-05 22.8 0.0 0.00042 20.8 0.0 2.1 1 1 1 2 2 2 1 Miro-like protein AAA_17 PF13207.1 EIE84873.1 - 0.00014 22.6 1.2 0.00037 21.3 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EIE84873.1 - 0.00048 20.1 0.0 0.00096 19.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EIE84873.1 - 0.0014 18.9 1.7 0.0033 17.7 1.2 1.7 1 1 0 1 1 1 1 ABC transporter DUF258 PF03193.11 EIE84873.1 - 0.0016 17.6 0.0 0.0042 16.2 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function, DUF258 ArgK PF03308.11 EIE84873.1 - 0.0032 16.2 1.8 0.21 10.3 0.0 3.1 2 1 1 3 3 3 1 ArgK protein AAA_18 PF13238.1 EIE84873.1 - 0.0045 17.2 0.0 0.012 15.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EIE84873.1 - 0.0052 16.2 0.0 0.023 14.1 0.0 2.1 2 1 0 2 2 2 1 AAA-like domain GTP_EFTU PF00009.22 EIE84873.1 - 0.0089 15.4 2.3 0.12 11.7 0.0 2.4 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain AAA_14 PF13173.1 EIE84873.1 - 0.013 15.3 0.0 0.045 13.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain Arf PF00025.16 EIE84873.1 - 0.014 14.6 1.9 0.054 12.7 0.0 2.6 3 1 1 4 4 4 0 ADP-ribosylation factor family AAA_22 PF13401.1 EIE84873.1 - 0.025 14.7 0.1 0.07 13.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 EIE84873.1 - 0.035 13.5 0.0 0.067 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EIE84873.1 - 0.086 12.3 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Guanylate_kin PF00625.16 EIE84873.1 - 0.087 12.2 0.0 0.19 11.1 0.0 1.6 1 0 0 1 1 1 0 Guanylate kinase FtsK_SpoIIIE PF01580.13 EIE84873.1 - 0.11 12.0 0.0 0.27 10.6 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_33 PF13671.1 EIE84873.1 - 0.15 11.9 0.0 0.4 10.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 EIE84874.1 - 2.4e-15 56.5 0.0 5.1e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EIE84874.1 - 1.4e-05 24.4 0.1 9.3e-05 21.7 0.1 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 EIE84874.1 - 0.00022 20.4 0.2 0.0008 18.6 0.2 2.0 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 EIE84874.1 - 0.00061 20.2 0.1 0.0086 16.5 0.0 2.4 1 1 0 1 1 1 1 Miro-like protein Dynamin_N PF00350.18 EIE84874.1 - 0.00098 18.9 0.8 0.0036 17.1 0.6 2.3 1 1 0 1 1 1 1 Dynamin family MobB PF03205.9 EIE84874.1 - 0.0051 16.5 0.1 0.082 12.6 0.0 2.3 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 EIE84874.1 - 0.0084 15.5 0.1 0.07 12.6 0.1 2.1 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 EIE84874.1 - 0.015 14.4 0.0 0.041 13.1 0.0 1.7 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Septin PF00735.13 EIE84874.1 - 0.021 13.8 0.4 0.16 10.9 0.0 2.3 2 1 0 2 2 2 0 Septin AAA_17 PF13207.1 EIE84874.1 - 0.034 14.9 0.0 0.067 14.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EIE84874.1 - 0.059 13.6 0.3 0.19 12.0 0.2 2.1 1 1 0 1 1 1 0 ABC transporter AAA_18 PF13238.1 EIE84874.1 - 0.067 13.4 0.1 0.18 12.1 0.1 1.9 1 1 0 1 1 1 0 AAA domain Velvet PF11754.3 EIE84876.1 - 2e-35 122.2 1.0 2.5e-35 121.9 0.7 1.0 1 0 0 1 1 1 1 Velvet factor Ferritin PF00210.19 EIE84877.1 - 0.0012 18.5 0.3 0.0036 17.0 0.2 1.7 1 0 0 1 1 1 1 Ferritin-like domain Syntaxin PF00804.20 EIE84877.1 - 0.0041 17.2 5.0 0.0074 16.4 0.6 2.7 2 0 0 2 2 2 1 Syntaxin NuA4 PF09340.5 EIE84877.1 - 0.013 15.1 0.8 0.35 10.5 0.0 2.7 2 0 0 2 2 2 0 Histone acetyltransferase subunit NuA4 LUC7 PF03194.10 EIE84877.1 - 0.48 9.9 3.9 1 8.8 2.7 1.5 1 0 0 1 1 1 0 LUC7 N_terminus DASH_Dam1 PF08653.5 EIE84877.1 - 0.78 9.5 3.1 1.3 8.8 0.2 2.7 2 1 1 3 3 3 0 DASH complex subunit Dam1 ATP-synt_ab PF00006.20 EIE84878.1 - 8.9e-62 208.3 0.0 1.3e-61 207.8 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EIE84878.1 - 1.6e-16 60.7 0.2 3.5e-16 59.6 0.1 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EIE84878.1 - 2.2e-11 43.8 0.5 4.8e-11 42.7 0.4 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EIE84878.1 - 0.0011 18.7 0.3 0.0023 17.7 0.2 1.5 1 0 0 1 1 1 1 HAS barrel domain NEP PF10167.4 EIE84880.1 - 3.3e-13 49.3 1.0 5e-13 48.7 0.7 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein SR-25 PF10500.4 EIE84880.1 - 7.5 5.9 14.3 1 8.7 7.1 1.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Homeobox PF00046.24 EIE84885.1 - 1.5e-21 75.7 1.9 3e-21 74.7 1.3 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EIE84885.1 - 0.0012 18.5 0.1 0.0032 17.1 0.1 1.8 1 0 0 1 1 1 1 Homeobox KN domain Remorin_C PF03763.8 EIE84885.1 - 0.031 13.7 0.2 0.047 13.2 0.1 1.3 1 0 0 1 1 1 0 Remorin, C-terminal region KTI12 PF08433.5 EIE84887.1 - 1.2e-59 201.7 0.1 1.9e-45 155.2 0.0 2.0 1 1 1 2 2 2 2 Chromatin associated protein KTI12 AAA_33 PF13671.1 EIE84887.1 - 0.0066 16.3 0.0 1.8 8.4 0.0 2.6 1 1 1 2 2 2 2 AAA domain AAA_17 PF13207.1 EIE84887.1 - 0.021 15.6 0.1 0.07 13.9 0.1 1.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EIE84887.1 - 0.026 14.8 0.1 0.074 13.3 0.1 1.9 1 1 0 1 1 1 0 AAA domain cobW PF02492.14 EIE84887.1 - 0.065 12.6 0.0 0.099 12.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DDE_3 PF13358.1 EIE84888.1 - 4.7e-20 71.8 0.1 8.5e-20 70.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE84888.1 - 1.9e-08 34.2 2.3 2.9e-08 33.6 0.3 2.2 1 1 1 2 2 2 1 Transposase rve PF00665.21 EIE84888.1 - 0.042 13.9 0.1 0.11 12.5 0.0 1.9 2 0 0 2 2 2 0 Integrase core domain HTH_12 PF08461.5 EIE84888.1 - 0.11 12.2 0.1 0.34 10.6 0.0 1.8 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain DUF1033 PF06279.6 EIE84888.1 - 0.36 10.6 0.0 0.36 10.6 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1033) HTH_29 PF13551.1 EIE84888.1 - 0.48 10.5 3.7 0.45 10.6 1.2 2.0 2 1 0 2 2 2 0 Winged helix-turn helix HTH_32 PF13565.1 EIE84888.1 - 1.3 9.8 6.5 0.39 11.5 0.8 2.7 4 0 0 4 4 4 0 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.1 EIE84888.1 - 1.7 7.8 3.8 1.1 8.5 0.1 2.4 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 HTH_21 PF13276.1 EIE84888.1 - 1.9 8.5 5.1 1 9.4 0.1 2.7 3 0 0 3 3 3 0 HTH-like domain Asp_protease PF09668.5 EIE84889.1 - 1.3e-10 40.9 0.0 2.6e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 EIE84889.1 - 7.4e-09 36.0 0.0 1.9e-08 34.6 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 EIE84889.1 - 9.8e-07 28.6 0.4 4.3e-06 26.5 0.0 2.4 2 0 0 2 2 2 1 Retroviral aspartyl protease RVP_2 PF08284.6 EIE84889.1 - 2.3e-06 27.5 0.0 4.7e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EIE84889.1 - 3.4e-06 26.7 0.1 7.4e-06 25.7 0.1 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Cyt_c_ox_IV PF12270.3 EIE84889.1 - 0.071 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV Transposase_21 PF02992.9 EIE84891.1 - 4.2e-22 78.3 0.0 9.1e-22 77.2 0.0 1.5 1 0 0 1 1 1 1 Transposase family tnp2 DUF1258 PF06869.7 EIE84891.1 - 0.0017 17.5 0.0 0.0027 16.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) Med15 PF09606.5 EIE84892.1 - 0.028 12.6 12.5 0.04 12.1 8.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal FlgM PF04316.8 EIE84892.1 - 2.2 8.2 5.1 13 5.8 2.9 2.3 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM Med15 PF09606.5 EIE84893.1 - 0.0055 14.9 12.5 0.0078 14.4 8.6 1.3 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal DEC-1_N PF04625.8 EIE84893.1 - 0.81 8.3 17.2 1.6 7.2 11.9 1.5 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region rve PF00665.21 EIE84894.1 - 1.1e-18 67.4 0.0 2.5e-18 66.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE84894.1 - 4e-16 59.0 0.6 8.4e-16 57.9 0.1 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE84894.1 - 1.9e-13 49.8 1.8 4.4e-13 48.6 1.3 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.12 EIE84895.1 - 0.00029 20.8 0.0 0.00054 19.9 0.0 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein rve PF00665.21 EIE84896.1 - 3.6e-19 69.0 0.0 8.8e-19 67.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE84896.1 - 3e-16 59.4 0.6 7.9e-16 58.0 0.1 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE84896.1 - 4.4e-14 51.8 1.1 1e-13 50.7 0.7 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.1 EIE84896.1 - 3.9e-05 24.0 0.0 9.8e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 EIE84896.1 - 7.2e-05 22.6 0.2 0.00027 20.7 0.1 2.0 1 0 0 1 1 1 1 Retroviral aspartyl protease DDE_3 PF13358.1 EIE84897.1 - 4.5e-21 75.1 0.1 8.5e-21 74.2 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE84897.1 - 1.4e-15 57.0 4.3 4.9e-15 55.3 0.2 3.0 4 0 0 4 4 3 1 Transposase HTH_29 PF13551.1 EIE84897.1 - 6.4e-06 26.2 0.2 6.4e-06 26.2 0.1 1.7 2 0 0 2 2 1 1 Winged helix-turn helix HTH_32 PF13565.1 EIE84897.1 - 7.9e-05 23.3 3.3 0.0077 17.0 0.1 3.7 3 1 1 4 4 4 1 Homeodomain-like domain HTH_38 PF13936.1 EIE84897.1 - 8.6e-05 22.0 0.1 0.0002 20.8 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.1 EIE84897.1 - 0.00016 21.1 0.1 0.0031 17.1 0.0 2.5 2 0 0 2 2 2 1 Homeodomain-like domain Sigma70_r4_2 PF08281.7 EIE84897.1 - 0.0009 18.6 1.0 0.003 16.9 0.0 2.3 3 0 0 3 3 3 1 Sigma-70, region 4 HTH_28 PF13518.1 EIE84897.1 - 0.00091 19.1 0.1 0.0052 16.7 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_21 PF13276.1 EIE84897.1 - 0.001 19.0 0.3 0.08 12.9 0.0 2.9 3 0 0 3 3 2 1 HTH-like domain rve PF00665.21 EIE84897.1 - 0.0029 17.7 0.0 0.0094 16.0 0.0 2.0 2 1 0 2 2 2 1 Integrase core domain HTH_7 PF02796.10 EIE84897.1 - 0.0046 16.7 2.6 0.11 12.4 0.2 2.8 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase HTH_Tnp_4 PF13613.1 EIE84897.1 - 0.023 14.2 0.4 0.05 13.1 0.0 1.6 2 0 0 2 2 2 0 Helix-turn-helix of DDE superfamily endonuclease GerE PF00196.14 EIE84897.1 - 0.029 13.6 0.0 0.51 9.7 0.0 2.3 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family Sigma70_r4 PF04545.11 EIE84897.1 - 0.066 12.5 0.6 0.23 10.7 0.0 2.1 3 0 0 3 3 3 0 Sigma-70, region 4 CPSase_L_D3 PF02787.14 EIE84897.1 - 0.1 12.3 0.0 0.27 11.0 0.0 1.7 2 0 0 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain HTH_40 PF14493.1 EIE84897.1 - 0.12 12.5 0.1 0.32 11.2 0.1 1.8 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.1 EIE84897.1 - 0.84 8.8 3.0 14 4.9 0.1 3.0 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 Exo_endo_phos_2 PF14529.1 EIE84898.1 - 8.8e-22 76.9 1.2 1.5e-21 76.1 0.5 1.7 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EIE84898.1 - 1.7e-08 34.7 2.2 3.1e-08 33.8 1.5 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Imm15 PF15590.1 EIE84900.1 - 0.096 11.7 0.2 0.34 10.0 0.1 1.9 2 0 0 2 2 2 0 Immunity protein 15 Complex1_LYR PF05347.10 EIE84900.1 - 0.13 12.0 0.3 0.92 9.3 0.0 2.4 3 0 0 3 3 3 0 Complex 1 protein (LYR family) DUF445 PF04286.7 EIE84900.1 - 0.58 9.6 8.8 2 7.8 6.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF445) RRP7 PF12923.2 EIE84900.1 - 0.68 9.9 4.4 0.21 11.6 0.6 1.9 2 0 0 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) LAGLIDADG_1 PF00961.14 EIE84900.1 - 4 8.0 6.3 2.5 8.7 2.2 2.1 1 1 1 2 2 2 0 LAGLIDADG endonuclease DDE_3 PF13358.1 EIE84902.1 - 5.6e-20 71.5 0.1 1.1e-19 70.5 0.1 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE84902.1 - 1e-18 67.1 2.3 1.9e-18 66.3 0.6 2.2 3 0 0 3 3 3 1 Transposase HTH_29 PF13551.1 EIE84902.1 - 2.1e-08 34.3 0.7 6.5e-08 32.6 0.5 1.8 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EIE84902.1 - 0.00072 19.1 0.8 0.0069 16.0 0.0 2.8 3 0 0 3 3 3 1 Homeodomain-like domain HTH_32 PF13565.1 EIE84902.1 - 0.0015 19.3 0.2 0.0015 19.3 0.1 3.9 5 1 1 6 6 5 1 Homeodomain-like domain Ku_PK_bind PF08785.6 EIE84902.1 - 0.006 16.4 0.1 0.015 15.1 0.0 1.8 2 0 0 2 2 2 1 Ku C terminal domain like rve PF00665.21 EIE84902.1 - 0.0091 16.1 0.0 0.031 14.3 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain HTH_28 PF13518.1 EIE84902.1 - 0.016 15.2 0.0 0.061 13.3 0.0 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_21 PF13276.1 EIE84902.1 - 0.029 14.3 0.0 0.28 11.2 0.0 2.5 2 0 0 2 2 2 0 HTH-like domain HTH_40 PF14493.1 EIE84902.1 - 0.04 14.1 0.3 0.95 9.7 0.0 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain Trp_repressor PF01371.14 EIE84902.1 - 0.074 12.9 0.0 0.54 10.2 0.0 2.2 2 0 0 2 2 2 0 Trp repressor protein HTH_17 PF12728.2 EIE84902.1 - 0.2 11.9 2.3 0.94 9.7 0.1 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.13 EIE84906.1 - 5.3e-08 32.7 0.5 1.2e-07 31.6 0.0 1.7 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 EIE84906.1 - 0.0018 18.4 0.1 0.0057 16.7 0.1 1.8 2 1 0 2 2 2 1 Winged helix-turn helix HTH_Tnp_ISL3 PF13542.1 EIE84907.1 - 3.3e-05 22.9 0.3 4e-05 22.6 0.2 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_28 PF13518.1 EIE84907.1 - 7.8e-05 22.5 0.0 9.7e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.1 EIE84907.1 - 7.9e-05 22.1 0.1 9.2e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 Homeodomain-like domain HTH_11 PF08279.7 EIE84907.1 - 0.0053 16.3 0.1 0.0064 16.1 0.1 1.2 1 0 0 1 1 1 1 HTH domain Sigma70_r4_2 PF08281.7 EIE84907.1 - 0.015 14.7 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 Sigma-70, region 4 GerE PF00196.14 EIE84907.1 - 0.051 12.8 0.0 0.063 12.6 0.0 1.2 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family HTH_38 PF13936.1 EIE84907.1 - 0.052 13.1 0.0 0.057 12.9 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_30 PF13556.1 EIE84907.1 - 0.068 12.7 0.1 0.086 12.4 0.1 1.1 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain HTH_DeoR PF08220.7 EIE84907.1 - 0.069 12.6 0.1 0.086 12.3 0.1 1.1 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain HTH_Tnp_1 PF01527.15 EIE84907.1 - 0.094 12.6 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 Transposase MerR PF00376.18 EIE84907.1 - 0.11 12.0 0.3 0.17 11.4 0.2 1.3 1 0 0 1 1 1 0 MerR family regulatory protein HTH_AsnC-type PF13404.1 EIE84907.1 - 0.11 11.9 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain DUF569 PF04601.8 EIE84908.1 - 0.014 14.8 0.2 0.1 12.0 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF569) HTH_12 PF08461.5 EIE84908.1 - 0.033 13.9 0.0 0.064 12.9 0.0 1.4 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain Aminotran_1_2 PF00155.16 EIE84910.1 - 3.5e-10 39.3 0.0 4.3e-10 39.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cyclin PF08613.6 EIE84911.1 - 1.2e-10 41.9 0.1 1.3e-10 41.8 0.1 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EIE84911.1 - 1e-08 34.7 0.1 1.3e-08 34.4 0.1 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain Baculo_FP PF03258.9 EIE84911.1 - 0.043 12.9 0.0 0.059 12.4 0.0 1.1 1 0 0 1 1 1 0 Baculovirus FP protein CD34_antigen PF06365.7 EIE84913.1 - 0.0011 18.6 0.0 0.0011 18.6 0.0 1.9 2 1 0 2 2 2 1 CD34/Podocalyxin family TMEM190 PF15431.1 EIE84913.1 - 0.0025 17.7 0.1 0.0049 16.7 0.0 1.4 1 0 0 1 1 1 1 Transmembrane protein 190 7TM_GPCR_Srv PF10323.4 EIE84913.1 - 0.0059 15.7 0.1 0.0083 15.2 0.1 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv DUF4366 PF14283.1 EIE84913.1 - 0.013 14.9 0.0 0.018 14.4 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) DUF3609 PF12259.3 EIE84913.1 - 0.017 13.7 0.0 0.026 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3609) Peptidase_M56 PF05569.6 EIE84913.1 - 0.036 13.0 0.0 0.05 12.5 0.0 1.3 1 0 0 1 1 1 0 BlaR1 peptidase M56 EphA2_TM PF14575.1 EIE84913.1 - 0.16 12.3 0.3 0.16 12.3 0.2 2.3 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF605 PF04652.11 EIE84913.1 - 0.3 10.4 11.2 0.34 10.2 7.7 1.1 1 0 0 1 1 1 0 Vta1 like Macoilin PF09726.4 EIE84913.1 - 2.3 6.3 17.1 3.4 5.8 11.8 1.2 1 0 0 1 1 1 0 Transmembrane protein DUF843 PF05814.6 EIE84913.1 - 3.3 7.5 5.3 7 6.5 0.5 2.5 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) Rhodanese PF00581.15 EIE84915.1 - 3.1e-10 40.3 0.0 7.1e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain MFS_1 PF07690.11 EIE84916.1 - 4.7e-07 28.8 9.8 6.1e-07 28.4 6.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3278 PF11683.3 EIE84916.1 - 0.057 13.4 0.2 0.057 13.4 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3278) RDD PF06271.7 EIE84916.1 - 8.8 6.2 14.0 1.5e+02 2.2 9.7 2.5 1 1 0 1 1 1 0 RDD family DUF3128 PF11326.3 EIE84917.1 - 0.082 13.0 0.0 0.1 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3128) Homeobox PF00046.24 EIE84918.1 - 1.2e-07 31.1 1.9 3e-07 29.9 1.3 1.7 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EIE84918.1 - 0.00013 21.6 0.3 0.0004 20.0 0.2 1.9 1 0 0 1 1 1 1 Homeobox KN domain D-ser_dehydrat PF14031.1 EIE84919.1 - 2e-16 59.9 0.0 5.6e-16 58.5 0.0 1.8 2 0 0 2 2 2 1 Putative serine dehydratase domain Ala_racemase_N PF01168.15 EIE84919.1 - 9.4e-16 58.0 0.1 1.3e-15 57.5 0.1 1.3 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain DLH PF01738.13 EIE84919.1 - 0.0077 15.5 0.6 0.015 14.5 0.4 1.5 1 0 0 1 1 1 1 Dienelactone hydrolase family ArsC PF03960.10 EIE84919.1 - 0.016 15.2 0.1 0.29 11.2 0.0 2.2 2 0 0 2 2 2 0 ArsC family tRNA-synt_1 PF00133.17 EIE84921.1 - 1.6e-123 412.8 3.5 6.6e-71 239.0 0.0 2.0 1 1 1 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EIE84921.1 - 3.1e-16 59.0 1.2 3.8e-09 35.6 0.1 3.0 2 1 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 EIE84921.1 - 8.1e-09 35.0 0.1 9.5e-08 31.5 0.0 2.4 1 1 2 3 3 3 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1c PF00749.16 EIE84921.1 - 0.028 13.0 0.4 2.6 6.6 0.1 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1d PF00750.14 EIE84921.1 - 0.064 12.0 0.1 0.27 9.9 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetases class I (R) ABC_membrane PF00664.18 EIE84922.1 - 1.4e-102 342.8 29.4 7.9e-53 179.6 12.6 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EIE84922.1 - 7.6e-70 233.5 0.1 7.9e-34 116.8 0.0 2.9 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EIE84922.1 - 5.1e-16 58.5 0.0 1.1e-06 28.1 0.1 3.8 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EIE84922.1 - 1.4e-10 41.4 0.3 0.00024 21.1 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.1 EIE84922.1 - 7.7e-10 39.2 0.5 0.62 9.9 0.0 4.9 5 0 0 5 5 5 2 AAA domain ABC_ATPase PF09818.4 EIE84922.1 - 2e-08 33.2 1.1 0.00011 20.9 0.0 2.7 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_22 PF13401.1 EIE84922.1 - 5.4e-08 33.0 1.7 0.0047 17.0 0.1 4.0 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EIE84922.1 - 1.6e-07 30.7 0.5 0.015 14.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EIE84922.1 - 6.2e-07 30.2 0.0 0.018 15.8 0.0 3.0 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EIE84922.1 - 1.8e-06 27.2 0.0 0.023 13.9 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA PF00004.24 EIE84922.1 - 3.3e-06 27.3 1.6 0.57 10.3 0.4 4.3 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 EIE84922.1 - 4.2e-06 26.4 0.2 0.12 11.9 0.0 3.9 2 2 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 EIE84922.1 - 2.4e-05 24.1 2.6 0.051 13.4 0.1 3.7 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.1 EIE84922.1 - 5e-05 23.1 0.0 0.37 10.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 EIE84922.1 - 0.0001 21.4 0.0 0.28 10.2 0.0 3.0 3 0 0 3 3 3 2 Zeta toxin MobB PF03205.9 EIE84922.1 - 0.00051 19.7 0.0 0.95 9.1 0.0 2.8 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 EIE84922.1 - 0.00058 19.3 0.9 0.67 9.3 0.0 3.2 3 0 0 3 3 3 1 AAA-like domain AAA_14 PF13173.1 EIE84922.1 - 0.00073 19.4 0.0 1.4 8.8 0.0 3.3 4 0 0 4 4 2 1 AAA domain AAA_5 PF07728.9 EIE84922.1 - 0.001 18.7 0.0 2.1 8.0 0.0 3.4 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Rad17 PF03215.10 EIE84922.1 - 0.0034 16.1 0.0 0.12 10.9 0.0 2.3 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_18 PF13238.1 EIE84922.1 - 0.0059 16.9 0.1 5.6 7.2 0.0 3.2 3 0 0 3 3 2 0 AAA domain AAA_28 PF13521.1 EIE84922.1 - 0.0061 16.5 0.1 2.1 8.2 0.1 2.8 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EIE84922.1 - 0.0072 16.4 0.0 4.5 7.4 0.0 2.9 2 0 0 2 2 2 1 RNA helicase AAA_25 PF13481.1 EIE84922.1 - 0.015 14.6 2.5 11 5.4 0.0 3.9 4 0 0 4 4 4 0 AAA domain AAA_19 PF13245.1 EIE84922.1 - 0.019 14.6 3.5 0.98 9.2 0.0 3.8 5 0 0 5 5 3 0 Part of AAA domain DUF2207 PF09972.4 EIE84922.1 - 0.025 13.1 6.2 0.035 12.6 0.0 3.2 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) Nuc_deoxyrib_tr PF05014.10 EIE84922.1 - 0.029 14.2 0.1 7.7 6.4 0.0 2.9 2 0 0 2 2 2 0 Nucleoside 2-deoxyribosyltransferase G-alpha PF00503.15 EIE84922.1 - 0.038 12.6 7.6 0.77 8.3 0.0 3.0 3 0 0 3 3 2 0 G-protein alpha subunit MMR_HSR1 PF01926.18 EIE84922.1 - 0.046 13.6 0.1 9.3 6.2 0.0 3.2 4 0 0 4 4 3 0 50S ribosome-binding GTPase APS_kinase PF01583.15 EIE84922.1 - 0.051 13.2 0.0 20 4.7 0.0 3.3 3 0 0 3 3 3 0 Adenylylsulphate kinase NACHT PF05729.7 EIE84922.1 - 0.067 12.8 0.1 13 5.4 0.0 2.6 2 0 0 2 2 2 0 NACHT domain Chitin_synth_1 PF01644.12 EIE84922.1 - 0.94 9.2 3.9 18 5.0 0.1 3.5 3 1 1 4 4 3 0 Chitin synthase UCH PF00443.24 EIE84923.1 - 8.4e-42 143.1 0.0 2.1e-41 141.8 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.1 EIE84923.1 - 1.5e-41 142.2 12.6 1.5e-41 142.2 8.7 2.3 2 0 0 2 2 2 1 Ubiquitin-specific protease C-terminal UCH_1 PF13423.1 EIE84923.1 - 2.5e-21 76.3 0.0 4.4e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.3 EIE84923.1 - 3.7e-18 65.6 11.5 4.2e-07 29.4 0.1 6.3 1 1 4 5 5 5 3 ICP0-binding domain of Ubiquitin-specific protease 7 MATH PF00917.21 EIE84923.1 - 8.4e-12 45.3 0.0 8.4e-12 45.3 0.0 2.6 3 0 0 3 3 3 1 MATH domain ADIP PF11559.3 EIE84924.1 - 0.00013 21.8 23.9 0.00013 21.8 16.6 2.5 1 1 1 2 2 2 1 Afadin- and alpha -actinin-Binding HATPase_c_4 PF13749.1 EIE84924.1 - 0.1 12.3 0.7 0.32 10.8 0.5 1.8 1 0 0 1 1 1 0 ATP-dependent DNA helicase recG C-terminal TraG_N PF07916.6 EIE84924.1 - 0.19 10.0 5.6 0.29 9.5 3.9 1.3 1 0 0 1 1 1 0 TraG-like protein, N-terminal region DUF3271 PF11675.3 EIE84924.1 - 0.28 10.2 8.9 5.4 6.0 4.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3271) Ax_dynein_light PF10211.4 EIE84924.1 - 5.4 6.7 44.9 0.83 9.4 7.7 3.2 1 1 2 3 3 3 0 Axonemal dynein light chain HSP70 PF00012.15 EIE84924.1 - 6 4.6 20.1 7.7 4.2 13.9 1.1 1 0 0 1 1 1 0 Hsp70 protein CALCOCO1 PF07888.6 EIE84924.1 - 9.3 4.4 32.3 0.51 8.5 6.4 2.7 1 1 2 3 3 3 0 Calcium binding and coiled-coil domain (CALCOCO1) like Pex24p PF06398.6 EIE84925.1 - 4.6e-16 58.5 16.8 6.5e-16 58.0 11.7 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Cation_efflux PF01545.16 EIE84926.1 - 1.3e-22 80.1 16.1 1.2e-11 44.2 4.9 3.8 1 1 2 3 3 3 3 Cation efflux family DUF1379 PF07126.7 EIE84926.1 - 0.03 13.6 2.2 0.28 10.5 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1379) ABC_membrane PF00664.18 EIE84927.1 - 5.5e-42 144.0 9.6 7.5e-42 143.6 6.7 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EIE84927.1 - 1.2e-28 100.1 0.0 2.9e-28 98.8 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_17 PF13207.1 EIE84927.1 - 2.8e-05 24.9 0.0 5.7e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain ABC_membrane_2 PF06472.10 EIE84927.1 - 0.00044 19.4 0.5 0.00067 18.8 0.4 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 AAA_18 PF13238.1 EIE84927.1 - 0.0005 20.3 0.0 0.0024 18.1 0.0 2.1 3 0 0 3 3 2 1 AAA domain AAA_29 PF13555.1 EIE84927.1 - 0.0046 16.4 0.2 0.0098 15.4 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain APS_kinase PF01583.15 EIE84927.1 - 0.0067 16.0 0.0 0.016 14.8 0.0 1.7 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_21 PF13304.1 EIE84927.1 - 0.011 15.7 0.0 0.033 14.1 0.0 1.8 1 1 1 2 2 2 0 AAA domain AAA_22 PF13401.1 EIE84927.1 - 0.012 15.7 0.0 0.066 13.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EIE84927.1 - 0.018 14.9 0.0 0.036 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 EIE84927.1 - 0.025 13.7 0.0 0.046 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 EIE84927.1 - 0.026 13.6 0.0 0.057 12.5 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.1 EIE84927.1 - 0.03 13.7 0.0 0.063 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EIE84927.1 - 0.032 14.2 0.0 0.12 12.3 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain SQS_PSY PF00494.14 EIE84927.1 - 0.038 13.2 0.0 0.066 12.4 0.0 1.3 1 0 0 1 1 1 0 Squalene/phytoene synthase ATG22 PF11700.3 EIE84928.1 - 1.5e-97 327.0 31.7 1.8e-97 326.8 22.0 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 EIE84928.1 - 1.3e-13 50.3 36.6 4.5e-06 25.6 6.2 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily Mito_carr PF00153.22 EIE84930.1 - 8.7e-65 214.4 1.6 1.1e-22 79.4 0.0 3.2 2 1 1 3 3 3 3 Mitochondrial carrier protein RRM_1 PF00076.17 EIE84931.1 - 6.8e-30 102.5 0.1 4.5e-15 55.0 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE84931.1 - 4.5e-18 65.0 0.1 9.4e-08 31.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE84931.1 - 1.6e-12 47.0 0.0 1e-07 31.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EIE84931.1 - 1.1e-07 31.6 0.2 0.00048 19.9 0.0 2.2 2 0 0 2 2 2 2 RNA binding motif Limkain-b1 PF11608.3 EIE84931.1 - 0.003 17.2 2.9 0.11 12.2 0.2 2.4 2 0 0 2 2 2 2 Limkain b1 DbpA PF03880.10 EIE84931.1 - 0.086 12.5 0.1 3.6 7.3 0.0 2.5 3 0 0 3 3 3 0 DbpA RNA binding domain AATase PF07247.7 EIE84932.1 - 1e-11 44.0 0.0 1.4e-11 43.6 0.0 1.2 1 1 0 1 1 1 1 Alcohol acetyltransferase AA_permease PF00324.16 EIE84933.1 - 3.3e-113 378.5 53.9 4.8e-81 272.4 19.9 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 EIE84933.1 - 1.5e-34 119.2 53.2 1.1e-26 93.3 23.1 2.3 1 1 1 2 2 2 2 Amino acid permease Spore_permease PF03845.8 EIE84933.1 - 0.33 9.5 26.1 0.49 8.9 0.2 4.0 4 0 0 4 4 4 0 Spore germination protein Ribosomal_S6e PF01092.14 EIE84935.1 - 5.3e-63 210.3 0.3 5.3e-63 210.3 0.2 1.9 2 0 0 2 2 2 1 Ribosomal protein S6e RhoGAP PF00620.22 EIE84936.1 - 2.1e-06 27.4 0.1 4.9e-06 26.2 0.0 1.6 1 1 0 1 1 1 1 RhoGAP domain SGL PF08450.7 EIE84939.1 - 0.065 12.5 0.0 0.14 11.5 0.0 1.5 1 1 0 1 1 1 0 SMP-30/Gluconolaconase/LRE-like region GTP_EFTU PF00009.22 EIE84940.1 - 1.8e-61 206.8 0.1 2.6e-61 206.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EIE84940.1 - 5.8e-36 122.6 0.0 1.5e-35 121.3 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 EIE84940.1 - 6.5e-23 80.4 0.0 1.6e-22 79.1 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EIE84940.1 - 5.5e-14 52.0 0.9 1.8e-13 50.3 0.1 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EIE84940.1 - 2.5e-13 49.6 0.0 5.6e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 EIE84940.1 - 0.00014 21.8 0.0 0.00032 20.6 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Nuc_sug_transp PF04142.10 EIE84941.1 - 3.8e-88 294.6 12.4 4.4e-88 294.5 8.6 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter EmrE PF13536.1 EIE84941.1 - 2.6e-07 30.8 1.1 2.6e-07 30.8 0.8 2.5 2 1 0 2 2 2 1 Multidrug resistance efflux transporter EamA PF00892.15 EIE84941.1 - 1.1e-05 25.4 21.1 1.1e-05 25.4 1.8 2.4 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 EIE84941.1 - 5e-05 22.3 12.2 0.00011 21.2 8.5 1.5 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.11 EIE84941.1 - 0.00087 18.9 2.4 0.00087 18.9 1.7 2.8 2 1 0 2 2 2 1 Triose-phosphate Transporter family Helicase_C_3 PF13625.1 EIE84942.1 - 9.5e-30 102.9 0.0 2.3e-28 98.5 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIE84942.1 - 6.5e-15 55.4 0.3 2.3e-14 53.6 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EIE84942.1 - 4.9e-12 45.2 0.0 8.1e-12 44.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EIE84942.1 - 1.9e-09 37.2 0.0 4.3e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EIE84942.1 - 6.9e-08 32.1 0.2 3.1e-07 30.0 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Ribosomal_S7e PF01251.13 EIE84943.1 - 6.7e-86 286.6 1.0 7.5e-86 286.4 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e DUF4174 PF13778.1 EIE84943.1 - 0.041 13.9 0.2 0.11 12.5 0.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4174) F-box-like PF12937.2 EIE84944.1 - 0.00015 21.4 1.9 0.00026 20.6 0.3 2.3 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 EIE84944.1 - 0.57 9.8 2.3 4.1 7.1 0.9 3.0 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) HTH_Tnp_Tc3_2 PF01498.13 EIE84946.1 - 6.2e-06 26.1 2.5 8.3e-06 25.7 1.8 1.2 1 0 0 1 1 1 1 Transposase DUF273 PF03314.9 EIE84946.1 - 0.068 12.4 3.4 0.096 11.9 0.6 1.9 1 1 1 2 2 2 0 Protein of unknown function, DUF273 Transket_pyr PF02779.19 EIE84947.1 - 1.4e-45 154.9 0.0 2.3e-45 154.2 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EIE84947.1 - 1.1e-35 122.2 0.0 2.4e-35 121.1 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain hSac2 PF12456.3 EIE84948.1 - 1.7e-20 72.5 0.6 3.1e-18 65.2 0.4 2.3 1 1 0 1 1 1 1 Inositol phosphatase PvlArgDC PF01862.11 EIE84948.1 - 0.13 11.8 0.0 0.31 10.6 0.0 1.5 1 1 0 1 1 1 0 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) DUF791 PF05631.9 EIE84949.1 - 2.1e-23 82.5 8.8 2.6e-16 59.2 3.2 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF791) MFS_1 PF07690.11 EIE84949.1 - 1.2e-05 24.2 13.8 0.00047 18.9 4.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4325 PF14213.1 EIE84949.1 - 0.076 12.6 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4325) DUF1286 PF06939.6 EIE84949.1 - 0.32 11.1 4.2 0.6 10.2 1.1 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF1286) DUF3755 PF12579.3 EIE84950.1 - 0.12 11.8 0.6 1.6 8.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3755) DUF4349 PF14257.1 EIE84950.1 - 0.13 11.5 1.7 0.13 11.4 0.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4349) DUF2951 PF11166.3 EIE84950.1 - 0.81 9.5 10.1 4.6 7.1 1.6 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2951) Fib_alpha PF08702.5 EIE84950.1 - 1.6 8.8 8.2 9.7 6.3 5.5 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family zf-C2HC_2 PF13913.1 EIE84951.1 - 0.018 14.6 0.7 0.029 14.0 0.5 1.4 1 0 0 1 1 1 0 zinc-finger of a C2HC-type BTB_2 PF02214.17 EIE84952.1 - 1.2e-11 44.6 0.4 8.2e-07 29.1 0.0 2.7 2 1 0 2 2 2 2 BTB/POZ domain DUF592 PF04574.8 EIE84952.1 - 0.023 14.2 2.3 0.39 10.2 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF592) zf-CCHC_4 PF14392.1 EIE84953.1 - 0.35 10.5 3.3 0.59 9.8 2.3 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-C3HC4_3 PF13920.1 EIE84953.1 - 0.44 10.2 4.6 0.54 9.9 3.2 1.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) NOC3p PF07540.6 EIE84954.1 - 1.5e-33 114.9 3.1 1.5e-33 114.9 2.2 3.1 3 0 0 3 3 3 1 Nucleolar complex-associated protein CBF PF03914.12 EIE84954.1 - 5.3e-24 84.5 0.2 5.3e-24 84.5 0.2 2.3 3 0 0 3 3 3 1 CBF/Mak21 family CRAL_TRIO PF00650.15 EIE84958.1 - 1.9e-20 72.9 0.1 3e-20 72.3 0.1 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 EIE84958.1 - 0.032 14.1 0.0 0.36 10.7 0.0 2.3 2 0 0 2 2 2 0 Divergent CRAL/TRIO domain TRAPPC9-Trs120 PF08626.6 EIE84959.1 - 2.9e-78 263.4 3.9 2.2e-77 260.5 2.7 2.2 1 1 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Mis12 PF05859.7 EIE84960.1 - 3.5e-06 26.8 3.9 3.5e-06 26.8 2.7 2.4 2 1 0 2 2 2 1 Mis12 protein DUF4349 PF14257.1 EIE84960.1 - 0.17 11.1 1.1 0.25 10.5 0.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4349) MutS_III PF05192.13 EIE84960.1 - 1.3 8.7 5.0 2.4 7.8 1.3 2.1 2 0 0 2 2 2 0 MutS domain III Fib_alpha PF08702.5 EIE84960.1 - 1.7 8.7 9.9 3 7.9 1.7 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family BTB PF00651.26 EIE84961.1 - 0.096 12.6 0.1 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain Pex14_N PF04695.8 EIE84961.1 - 1.9 8.5 4.5 17 5.4 3.1 2.3 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF605 PF04652.11 EIE84961.1 - 7.1 5.9 10.4 10 5.3 7.2 1.2 1 0 0 1 1 1 0 Vta1 like DUSP PF06337.7 EIE84962.1 - 0.0012 19.1 0.1 0.0035 17.7 0.1 1.7 1 0 0 1 1 1 1 DUSP domain zf-C3HC4_2 PF13923.1 EIE84962.1 - 0.045 13.7 5.8 0.83 9.7 4.2 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Anp1 PF03452.9 EIE84962.1 - 0.11 11.6 0.1 0.17 11.0 0.1 1.2 1 0 0 1 1 1 0 Anp1 zf-UBP PF02148.14 EIE84962.1 - 0.18 11.9 5.2 0.56 10.3 3.6 1.8 1 1 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein YyzF PF14116.1 EIE84962.1 - 0.21 11.5 4.0 13 5.8 0.7 2.6 2 0 0 2 2 2 0 YyzF-like protein Fis1_TPR_C PF14853.1 EIE84963.1 - 3.2e-16 58.9 0.0 5.7e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 EIE84963.1 - 9.1e-13 47.2 0.0 1.7e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat DUF357 PF04010.8 EIE84963.1 - 0.0025 17.4 0.0 0.0056 16.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF357) COPI_C PF06957.6 EIE84963.1 - 0.0035 15.9 0.0 0.0038 15.8 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus YopD PF05844.7 EIE84963.1 - 0.032 13.2 0.1 0.041 12.9 0.1 1.3 1 0 0 1 1 1 0 YopD protein zf-ribbon_3 PF13248.1 EIE84964.1 - 0.022 13.9 1.0 0.048 12.8 0.7 1.5 1 0 0 1 1 1 0 zinc-ribbon domain GPI-anchored PF10342.4 EIE84965.1 - 3.2e-08 33.9 0.5 4.4e-08 33.5 0.4 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family AWPM-19 PF05512.6 EIE84965.1 - 3.6 7.5 5.9 4.9 7.1 4.1 1.4 1 1 0 1 1 1 0 AWPM-19-like family Methyltransf_11 PF08241.7 EIE84966.1 - 0.02 15.3 0.0 0.11 12.9 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 EIE84966.1 - 0.053 13.2 0.0 0.47 10.1 0.0 2.1 1 1 1 2 2 2 0 Methyltransferase domain PAP_central PF04928.12 EIE84967.1 - 1.4e-99 331.9 0.0 1.9e-99 331.6 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 EIE84967.1 - 9e-09 35.0 0.4 4.3e-08 32.8 0.0 2.1 2 0 0 2 2 2 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 EIE84967.1 - 3.6e-05 24.0 0.1 0.00011 22.4 0.0 1.8 1 1 0 1 1 1 1 Nucleotidyltransferase domain DNA_pol_B_palm PF14792.1 EIE84967.1 - 0.055 13.5 0.0 0.19 11.8 0.0 2.0 1 1 0 1 1 1 0 DNA polymerase beta palm U1snRNP70_N PF12220.3 EIE84968.1 - 1.1e-21 76.9 4.3 1.4e-21 76.5 3.0 1.2 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal CH PF00307.26 EIE84968.1 - 0.09 12.8 0.1 0.11 12.5 0.1 1.2 1 0 0 1 1 1 0 Calponin homology (CH) domain DUF727 PF05303.7 EIE84969.1 - 1.2e-07 31.4 0.1 1.5e-07 31.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF727) Cbl_N PF02262.11 EIE84969.1 - 0.12 12.1 0.9 0.15 11.7 0.6 1.1 1 0 0 1 1 1 0 CBL proto-oncogene N-terminal domain 1 AHSA1 PF08327.6 EIE84970.1 - 4.8e-10 39.6 0.0 5.9e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Septin PF00735.13 EIE84971.1 - 1.6e-111 371.8 0.3 1.9e-111 371.6 0.2 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EIE84971.1 - 2e-07 30.9 0.0 3.5e-07 30.1 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EIE84971.1 - 7.7e-07 28.4 0.1 1.3e-06 27.6 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 EIE84971.1 - 6.5e-06 25.4 0.0 1.3e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.22 EIE84971.1 - 5.3e-05 22.7 0.1 0.00096 18.6 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_10 PF12846.2 EIE84971.1 - 0.00018 21.0 0.0 0.00048 19.6 0.0 1.7 2 0 0 2 2 2 1 AAA-like domain Dynamin_N PF00350.18 EIE84971.1 - 0.00046 20.0 1.1 0.54 10.0 0.3 2.7 1 1 1 2 2 2 2 Dynamin family ABC_tran PF00005.22 EIE84971.1 - 0.00067 19.9 0.0 0.0017 18.6 0.0 1.7 1 0 0 1 1 1 1 ABC transporter Gtr1_RagA PF04670.7 EIE84971.1 - 0.00099 18.3 0.2 0.0057 15.8 0.0 2.0 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region FtsK_SpoIIIE PF01580.13 EIE84971.1 - 0.001 18.6 0.1 0.0017 17.8 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_16 PF13191.1 EIE84971.1 - 0.0025 17.8 0.0 0.0086 16.0 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.17 EIE84971.1 - 0.0036 16.2 1.2 0.0043 15.9 0.1 1.6 2 0 0 2 2 2 1 NB-ARC domain Miro PF08477.8 EIE84971.1 - 0.0037 17.7 0.0 0.0089 16.5 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein AAA_22 PF13401.1 EIE84971.1 - 0.0054 16.8 0.0 0.011 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.2 EIE84971.1 - 0.0079 15.3 0.0 1.7 7.6 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 T2SE PF00437.15 EIE84971.1 - 0.012 14.5 0.5 0.029 13.2 0.2 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein Ras PF00071.17 EIE84971.1 - 0.013 14.8 0.0 0.032 13.6 0.0 1.7 1 1 0 1 1 1 0 Ras family AAA_29 PF13555.1 EIE84971.1 - 0.015 14.8 0.0 0.03 13.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.1 EIE84971.1 - 0.018 14.9 0.0 0.072 12.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EIE84971.1 - 0.021 15.1 0.0 0.052 13.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EIE84971.1 - 0.024 15.4 1.1 1.9 9.3 0.1 2.5 1 1 1 2 2 2 0 AAA domain DUF815 PF05673.8 EIE84971.1 - 0.06 12.2 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) IIGP PF05049.8 EIE84971.1 - 0.089 11.5 0.0 0.18 10.5 0.0 1.5 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_24 PF13479.1 EIE84971.1 - 0.1 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EIE84971.1 - 0.11 12.0 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_33 PF13671.1 EIE84971.1 - 0.11 12.3 0.0 0.38 10.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF3177 PF11375.3 EIE84972.1 - 0.26 10.7 0.1 0.4 10.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3177) ECH PF00378.15 EIE84973.1 - 1.1e-25 90.1 0.0 1.3e-25 89.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family PDT PF00800.13 EIE84973.1 - 0.091 12.2 0.1 0.23 10.9 0.1 1.5 1 1 0 1 1 1 0 Prephenate dehydratase Ribosomal_L29e PF01779.12 EIE84974.1 - 2.3e-22 78.5 14.1 3.3e-22 78.0 9.8 1.3 1 0 0 1 1 1 1 Ribosomal L29e protein family Aminotran_1_2 PF00155.16 EIE84975.1 - 3.7e-56 190.6 0.0 4.6e-56 190.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EIE84975.1 - 3.9e-05 22.8 0.0 6e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 EIE84975.1 - 0.0001 21.1 0.3 0.0016 17.2 0.2 2.1 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EIE84975.1 - 0.00046 18.5 0.0 0.0012 17.2 0.0 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 EIE84975.1 - 0.00062 18.9 0.0 0.00092 18.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Pkinase PF00069.20 EIE84976.1 - 4e-64 216.2 0.1 5.2e-64 215.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE84976.1 - 5e-31 107.7 0.0 6.7e-31 107.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EIE84976.1 - 0.0027 16.7 0.0 0.0064 15.5 0.0 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EIE84976.1 - 0.0052 16.1 0.4 1.3 8.3 0.0 2.3 2 0 0 2 2 2 2 PhoP regulatory network protein YrbL Tubulin PF00091.20 EIE84977.1 - 5.1e-60 202.9 0.0 7.3e-60 202.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EIE84977.1 - 2.8e-49 166.3 0.0 4.4e-49 165.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EIE84977.1 - 0.00025 20.5 0.0 0.00043 19.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Motile_Sperm PF00635.21 EIE84978.1 - 3.5e-26 90.9 1.0 6e-26 90.2 0.1 1.9 2 0 0 2 2 2 1 MSP (Major sperm protein) domain DUF904 PF06005.7 EIE84978.1 - 0.068 13.4 6.7 0.084 13.1 3.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF904) Mucin PF01456.12 EIE84978.1 - 0.075 12.8 20.1 0.12 12.0 13.9 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Apt1 PF10351.4 EIE84978.1 - 0.32 9.7 8.8 0.82 8.4 6.1 1.6 1 1 0 1 1 1 0 Golgi-body localisation protein domain IncA PF04156.9 EIE84978.1 - 2.4 7.7 8.7 0.34 10.4 3.0 1.8 2 0 0 2 2 2 0 IncA protein Dicty_REP PF05086.7 EIE84978.1 - 4.2 4.9 8.3 5 4.7 5.7 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Pkinase PF00069.20 EIE84979.1 - 1.2e-61 208.1 0.0 1.8e-61 207.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE84979.1 - 2.2e-24 85.9 0.0 3.3e-24 85.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIE84979.1 - 0.0007 19.3 0.0 0.0013 18.5 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EIE84979.1 - 0.037 12.8 0.1 0.081 11.7 0.1 1.5 1 0 0 1 1 1 0 Seadornavirus VP7 Kinase-like PF14531.1 EIE84979.1 - 0.038 12.9 0.0 0.11 11.3 0.0 1.8 1 1 0 1 1 1 0 Kinase-like Tropomyosin_1 PF12718.2 EIE84980.1 - 1e-21 77.3 31.4 1.5e-12 47.5 9.5 2.1 1 1 1 2 2 2 2 Tropomyosin like Tropomyosin PF00261.15 EIE84980.1 - 9e-10 38.0 25.3 9.7e-10 37.9 17.5 1.0 1 0 0 1 1 1 1 Tropomyosin DUF641 PF04859.7 EIE84980.1 - 0.002 17.8 16.8 0.0071 16.1 4.1 2.1 1 1 1 2 2 2 1 Plant protein of unknown function (DUF641) F420_oxidored PF03807.12 EIE84980.1 - 0.0058 17.0 0.9 0.0095 16.3 0.2 1.7 1 1 1 2 2 1 1 NADP oxidoreductase coenzyme F420-dependent MscS_porin PF12795.2 EIE84980.1 - 0.0061 15.9 23.5 0.0083 15.4 16.3 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain TMF_TATA_bd PF12325.3 EIE84980.1 - 0.0087 15.7 19.0 0.027 14.2 13.1 1.8 1 1 0 1 1 1 1 TATA element modulatory factor 1 TATA binding ERM PF00769.14 EIE84980.1 - 0.0088 15.6 28.0 0.0093 15.5 19.4 1.0 1 0 0 1 1 1 1 Ezrin/radixin/moesin family APG6 PF04111.7 EIE84980.1 - 0.054 12.5 25.3 0.063 12.3 17.5 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 WEMBL PF05701.6 EIE84980.1 - 0.055 11.9 24.6 0.14 10.5 17.0 1.7 1 1 0 1 1 1 0 Weak chloroplast movement under blue light AAA_13 PF13166.1 EIE84980.1 - 0.056 11.8 16.3 0.067 11.6 11.3 1.2 1 0 0 1 1 1 0 AAA domain Laminin_II PF06009.7 EIE84980.1 - 0.083 12.6 13.0 0.073 12.8 5.2 2.2 1 1 1 2 2 2 0 Laminin Domain II Laminin_I PF06008.9 EIE84980.1 - 0.15 11.3 20.4 0.79 8.9 14.1 1.9 1 1 0 1 1 1 0 Laminin Domain I EzrA PF06160.7 EIE84980.1 - 0.16 10.1 18.3 0.27 9.3 12.7 1.4 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA GAS PF13851.1 EIE84980.1 - 0.19 10.9 23.9 0.57 9.3 16.6 1.8 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Katanin_con80 PF13925.1 EIE84980.1 - 0.2 11.4 5.8 0.066 12.9 1.8 1.7 1 1 1 2 2 2 0 con80 domain of Katanin Xlink PF00193.12 EIE84980.1 - 0.24 11.4 2.6 13 5.9 0.1 2.2 2 0 0 2 2 2 0 Extracellular link domain CENP-F_leu_zip PF10473.4 EIE84980.1 - 0.3 10.9 26.4 3.3 7.5 9.6 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF812 PF05667.6 EIE84980.1 - 0.31 9.4 19.4 0.7 8.3 13.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF812) PspA_IM30 PF04012.7 EIE84980.1 - 0.39 10.0 25.5 3.1 7.0 9.6 2.4 1 1 1 2 2 2 0 PspA/IM30 family FH2 PF02181.18 EIE84980.1 - 0.43 9.4 12.2 0.62 8.8 8.4 1.3 1 1 0 1 1 1 0 Formin Homology 2 Domain PqqD PF05402.7 EIE84980.1 - 0.45 10.5 6.2 2.4 8.2 0.2 2.8 2 1 1 3 3 3 0 Coenzyme PQQ synthesis protein D (PqqD) DUF745 PF05335.8 EIE84980.1 - 0.46 9.9 19.8 0.28 10.6 8.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF745) IncA PF04156.9 EIE84980.1 - 0.47 10.0 27.0 0.75 9.3 18.7 1.4 1 1 0 1 1 1 0 IncA protein TMCO5 PF14992.1 EIE84980.1 - 0.47 9.5 18.4 0.52 9.4 12.8 1.1 1 0 0 1 1 1 0 TMCO5 family DUF869 PF05911.6 EIE84980.1 - 0.48 8.5 19.8 0.55 8.3 13.7 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) Med4 PF10018.4 EIE84980.1 - 0.53 9.6 17.6 0.8 9.0 4.9 2.1 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 TPR_MLP1_2 PF07926.7 EIE84980.1 - 0.54 9.9 27.7 0.31 10.7 14.1 2.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Cortex-I_coil PF09304.5 EIE84980.1 - 0.56 10.2 22.5 0.4 10.7 6.9 2.3 1 1 1 2 2 2 0 Cortexillin I, coiled coil BssS PF13991.1 EIE84980.1 - 0.57 9.9 3.2 0.5 10.1 0.2 2.3 1 1 2 3 3 3 0 BssS protein family TMF_DNA_bd PF12329.3 EIE84980.1 - 0.6 9.9 28.2 5.9e+03 -2.9 18.9 2.9 1 1 0 1 1 0 0 TATA element modulatory factor 1 DNA binding MAD PF05557.8 EIE84980.1 - 0.63 8.0 26.3 0.97 7.4 18.2 1.3 1 1 0 1 1 1 0 Mitotic checkpoint protein DUF4472 PF14739.1 EIE84980.1 - 0.65 10.4 16.5 2.7 8.4 10.4 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4472) DUF3584 PF12128.3 EIE84980.1 - 0.81 6.9 22.8 0.87 6.8 15.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ATG16 PF08614.6 EIE84980.1 - 0.82 9.4 23.1 75 3.0 16.0 2.1 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Striatin PF08232.7 EIE84980.1 - 0.89 9.8 15.0 1.2 9.4 10.4 1.3 1 0 0 1 1 1 0 Striatin family DUF1664 PF07889.7 EIE84980.1 - 1.1 9.0 9.3 3.1 7.6 2.3 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Med9 PF07544.8 EIE84980.1 - 1.1 8.9 19.5 1.2 8.9 3.1 2.7 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF4200 PF13863.1 EIE84980.1 - 1.2 9.1 26.8 4.7 7.1 14.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Spc7 PF08317.6 EIE84980.1 - 1.2 7.7 20.9 0.32 9.6 8.3 1.8 1 1 0 1 1 1 0 Spc7 kinetochore protein SlyX PF04102.7 EIE84980.1 - 1.2 9.5 20.9 1 9.7 2.5 2.9 1 1 2 3 3 3 0 SlyX AAA_27 PF13514.1 EIE84980.1 - 1.2 6.6 21.5 1.8 6.1 14.9 1.3 1 1 0 1 1 1 0 AAA domain Vac_Fusion PF02346.11 EIE84980.1 - 1.3 8.5 7.5 5 6.6 0.4 2.9 2 1 1 3 3 3 0 Chordopoxvirus fusion protein Nup54 PF13874.1 EIE84980.1 - 1.3 8.7 16.9 5.5 6.6 11.9 1.8 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 YscO PF07321.7 EIE84980.1 - 1.3 8.8 26.5 8.9 6.1 13.9 2.6 1 1 1 2 2 2 0 Type III secretion protein YscO ADIP PF11559.3 EIE84980.1 - 1.3 8.9 26.7 0.13 12.1 11.2 2.7 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding BLOC1_2 PF10046.4 EIE84980.1 - 1.4 9.1 16.8 11 6.2 5.1 2.5 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4201 PF13870.1 EIE84980.1 - 1.7 8.0 22.3 4.1 6.8 8.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) DUF1423 PF07227.6 EIE84980.1 - 1.7 7.1 16.3 1.9 7.0 11.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) IZUMO PF15005.1 EIE84980.1 - 1.8 8.6 7.5 29 4.6 5.2 2.1 1 1 0 1 1 1 0 Izumo sperm-egg fusion DUF724 PF05266.9 EIE84980.1 - 2 7.9 19.9 1.2 8.7 5.8 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF724) DUF3573 PF12097.3 EIE84980.1 - 2 6.9 4.0 2.4 6.7 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Fib_alpha PF08702.5 EIE84980.1 - 2.1 8.4 13.9 18 5.4 8.7 2.2 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Ax_dynein_light PF10211.4 EIE84980.1 - 2.2 8.0 21.5 2.6 7.8 3.5 2.3 1 1 1 2 2 2 0 Axonemal dynein light chain Syntaxin-6_N PF09177.6 EIE84980.1 - 2.2 8.7 14.2 1.3 9.5 5.4 2.5 1 1 1 2 2 2 0 Syntaxin 6, N-terminal TBPIP PF07106.8 EIE84980.1 - 2.4 7.6 21.7 2.6 7.5 8.1 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) V_ATPase_I PF01496.14 EIE84980.1 - 2.7 5.7 15.1 2.8 5.6 9.5 1.6 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family FliD_N PF02465.13 EIE84980.1 - 3 8.2 11.9 1.7 9.0 0.5 2.4 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus FlxA PF14282.1 EIE84980.1 - 4.1 7.3 19.8 1.1 9.2 5.2 3.0 1 1 2 3 3 3 0 FlxA-like protein DUF3150 PF11348.3 EIE84980.1 - 4.5 6.2 11.0 5.2 6.0 7.1 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3150) FadA PF09403.5 EIE84980.1 - 5 7.1 18.7 16 5.4 0.6 2.3 1 1 1 2 2 2 0 Adhesion protein FadA HSP70 PF00012.15 EIE84980.1 - 5.1 4.8 16.2 5.8 4.7 11.2 1.0 1 0 0 1 1 1 0 Hsp70 protein TMPIT PF07851.8 EIE84980.1 - 5.5 5.9 11.5 6.3 5.7 7.9 1.1 1 0 0 1 1 1 0 TMPIT-like protein Mnd1 PF03962.10 EIE84980.1 - 5.7 6.5 22.7 24 4.5 11.5 2.0 1 1 1 2 2 2 0 Mnd1 family ARD PF03079.9 EIE84980.1 - 7 6.5 10.6 1.1 9.1 0.4 2.1 1 1 1 2 2 2 0 ARD/ARD' family Seryl_tRNA_N PF02403.17 EIE84980.1 - 7.3 6.6 21.0 2.2 8.3 6.4 2.4 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Fmp27_WPPW PF10359.4 EIE84980.1 - 7.4 4.8 15.4 1.8 6.8 8.1 1.6 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain Peptidase_C6 PF00851.13 EIE84980.1 - 7.8 5.0 8.8 9 4.7 6.1 1.0 1 0 0 1 1 1 0 Helper component proteinase DUF4250 PF14056.1 EIE84980.1 - 7.8 6.3 7.6 3.2 7.5 0.1 3.2 2 2 2 4 4 4 0 Domain of unknown function (DUF4250) DUF3450 PF11932.3 EIE84980.1 - 8.8 5.5 21.1 3.5 6.8 8.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Spc24 PF08286.6 EIE84980.1 - 9 6.0 23.0 1.5 8.4 3.1 2.8 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 Cg6151-P PF10233.4 EIE84981.1 - 8.4e-16 57.9 4.2 1e-15 57.7 2.9 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P p12I PF12233.3 EIE84981.1 - 0.012 15.8 0.9 0.014 15.6 0.6 1.1 1 0 0 1 1 1 0 Human adult T cell leukemia/lymphoma virus protein Myb_DNA-binding PF00249.26 EIE84982.1 - 2.6e-21 75.4 0.1 1.2e-08 34.9 0.0 4.2 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EIE84982.1 - 4.3e-11 42.7 3.5 0.00019 21.4 0.1 4.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Pkinase PF00069.20 EIE84983.1 - 1.5e-41 142.2 0.0 3.7e-38 131.1 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIE84983.1 - 1.7e-18 66.6 0.0 3.6e-18 65.5 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE84983.1 - 0.0043 16.0 0.0 0.0061 15.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EIE84983.1 - 0.03 13.3 0.0 0.043 12.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIE84983.1 - 0.036 13.7 0.0 0.28 10.8 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family HLH PF00010.21 EIE84984.1 - 1e-17 63.5 3.2 1e-17 63.5 2.2 2.2 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain Pik1 PF11522.3 EIE84984.1 - 0.0046 16.6 0.2 0.017 14.8 0.0 2.1 2 0 0 2 2 2 1 Yeast phosphatidylinositol-4-OH kinase Pik1 EPL1 PF10513.4 EIE84985.1 - 0.0015 18.7 0.2 0.0017 18.6 0.1 1.1 1 0 0 1 1 1 1 Enhancer of polycomb-like IF-2B PF01008.12 EIE84987.1 - 2.4e-63 213.7 1.5 6.8e-63 212.2 1.1 1.7 1 1 0 1 1 1 1 Initiation factor 2 subunit family Merozoite_SPAM PF07133.6 EIE84987.1 - 2.5e-05 24.2 16.7 3.8e-05 23.6 11.6 1.2 1 0 0 1 1 1 1 Merozoite surface protein (SPAM) Daxx PF03344.10 EIE84987.1 - 0.008 14.7 8.3 0.0093 14.5 5.8 1.1 1 0 0 1 1 1 1 Daxx Family FRQ PF09421.5 EIE84987.1 - 0.0092 13.8 0.2 0.012 13.3 0.1 1.1 1 0 0 1 1 1 1 Frequency clock protein YL1 PF05764.8 EIE84987.1 - 0.017 14.7 14.1 0.025 14.1 9.8 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Vfa1 PF08432.5 EIE84987.1 - 0.035 14.1 7.3 0.051 13.5 5.1 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF1510 PF07423.6 EIE84987.1 - 0.056 12.8 6.6 0.085 12.2 4.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Sigma70_ner PF04546.8 EIE84987.1 - 0.057 13.0 13.1 0.087 12.4 9.1 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region CDC45 PF02724.9 EIE84987.1 - 0.066 11.2 10.2 0.097 10.6 7.1 1.2 1 0 0 1 1 1 0 CDC45-like protein alpha-hel2 PF14456.1 EIE84987.1 - 0.15 10.8 5.0 4.8 5.8 3.5 2.2 2 0 0 2 2 2 0 Alpha-helical domain 2 DUF966 PF06136.8 EIE84987.1 - 0.25 10.7 4.3 0.33 10.3 3.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Nop14 PF04147.7 EIE84987.1 - 0.44 8.4 16.0 0.57 8.0 11.1 1.1 1 0 0 1 1 1 0 Nop14-like family PBP_sp32 PF07222.7 EIE84987.1 - 0.44 9.6 5.2 0.77 8.8 3.6 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 BSP_II PF05432.6 EIE84987.1 - 0.49 9.6 13.4 0.8 8.9 9.3 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DNA_pol_phi PF04931.8 EIE84987.1 - 0.49 8.1 17.3 0.65 7.7 12.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi Sporozoite_P67 PF05642.6 EIE84987.1 - 0.53 8.0 7.0 0.74 7.6 4.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CENP-B_dimeris PF09026.5 EIE84987.1 - 0.73 10.1 12.5 1.4 9.2 8.7 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain XAP5 PF04921.9 EIE84987.1 - 0.82 9.1 13.9 1 8.8 9.1 1.6 2 0 0 2 2 1 0 XAP5, circadian clock regulator RRN3 PF05327.6 EIE84987.1 - 0.87 7.6 10.1 1.2 7.1 7.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 FAM176 PF14851.1 EIE84987.1 - 1.2 8.7 7.1 1.9 8.1 4.9 1.3 1 0 0 1 1 1 0 FAM176 family Pox_RNA_Pol_19 PF05320.7 EIE84987.1 - 2.2 7.9 10.9 3.8 7.2 7.6 1.3 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Myc_N PF01056.13 EIE84987.1 - 2.5 7.1 11.7 4 6.5 8.1 1.3 1 0 0 1 1 1 0 Myc amino-terminal region TRAP_alpha PF03896.11 EIE84987.1 - 2.8 6.8 8.6 4.5 6.1 5.9 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit TFIIF_alpha PF05793.7 EIE84987.1 - 8.3 4.6 18.4 9.4 4.4 11.1 1.9 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DNA_RNApol_7kD PF03604.8 EIE84988.1 - 3.6e-18 64.7 3.9 4.8e-18 64.3 2.7 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit NinF PF05810.7 EIE84988.1 - 0.00046 19.9 0.1 0.00051 19.7 0.1 1.1 1 0 0 1 1 1 1 NinF protein DZR PF12773.2 EIE84988.1 - 0.0015 18.3 1.6 0.0031 17.2 1.2 1.5 1 1 0 1 1 1 1 Double zinc ribbon HypA PF01155.14 EIE84988.1 - 0.0028 17.3 0.4 0.003 17.2 0.3 1.1 1 0 0 1 1 1 1 Hydrogenase expression/synthesis hypA family DUF2197 PF09963.4 EIE84988.1 - 0.0032 17.3 4.1 0.54 10.2 0.1 2.1 1 1 1 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2197) zf-NADH-PPase PF09297.6 EIE84988.1 - 0.0076 15.7 3.5 0.029 13.8 2.4 1.8 1 1 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain Zn_ribbon_recom PF13408.1 EIE84988.1 - 0.011 15.9 2.0 0.098 12.9 0.2 2.1 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain zf-ISL3 PF14690.1 EIE84988.1 - 0.018 15.0 2.3 0.033 14.2 0.3 2.0 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 TFIIS_C PF01096.13 EIE84988.1 - 0.018 14.6 0.9 2.7 7.6 0.2 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) GFA PF04828.9 EIE84988.1 - 0.022 14.7 0.6 2.3 8.2 0.1 2.0 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme OrfB_Zn_ribbon PF07282.6 EIE84988.1 - 0.027 14.1 0.3 0.032 13.9 0.2 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain DUF2296 PF10058.4 EIE84988.1 - 0.034 13.8 1.0 0.6 9.8 0.0 2.1 1 1 1 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) GATA PF00320.22 EIE84988.1 - 0.036 13.4 1.8 0.38 10.1 0.0 2.2 1 1 1 2 2 2 0 GATA zinc finger A2L_zn_ribbon PF08792.5 EIE84988.1 - 0.048 13.1 1.1 6.5 6.3 0.0 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain Zn-ribbon_8 PF09723.5 EIE84988.1 - 0.061 13.2 3.3 0.23 11.4 2.3 1.9 1 1 0 1 1 1 0 Zinc ribbon domain zinc_ribbon_6 PF14599.1 EIE84988.1 - 0.069 12.9 2.7 3.7 7.4 0.2 2.2 1 1 1 2 2 2 0 Zinc-ribbon zf-ribbon_3 PF13248.1 EIE84988.1 - 0.11 11.7 0.4 11 5.4 0.0 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Cas_CXXC_CXXC PF09706.5 EIE84988.1 - 0.11 12.6 2.7 2.2 8.5 0.3 2.1 1 1 1 2 2 2 0 CRISPR-associated protein (Cas_CXXC_CXXC) Zn_Tnp_IS1595 PF12760.2 EIE84988.1 - 0.13 12.1 2.3 1.8 8.4 1.5 2.0 1 1 2 3 3 3 0 Transposase zinc-ribbon domain zf-trcl PF13451.1 EIE84988.1 - 0.14 11.7 5.2 1.3 8.7 0.5 2.2 1 1 1 2 2 2 0 Probable zinc-binding domain zinc_ribbon_2 PF13240.1 EIE84988.1 - 0.17 11.4 1.6 3.4 7.2 1.1 2.1 1 1 0 1 1 1 0 zinc-ribbon domain zf-dskA_traR PF01258.12 EIE84988.1 - 0.19 11.5 2.7 3.6 7.4 0.2 2.2 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger DUF951 PF06107.6 EIE84988.1 - 0.21 11.1 0.5 0.21 11.1 0.4 1.5 2 0 0 2 2 1 0 Bacterial protein of unknown function (DUF951) YhfH PF14149.1 EIE84988.1 - 0.22 11.3 1.9 4.7 7.0 0.1 2.2 2 0 0 2 2 2 0 YhfH-like protein Lar_restr_allev PF14354.1 EIE84988.1 - 0.23 11.8 1.4 9.9 6.5 0.1 2.1 1 1 1 2 2 2 0 Restriction alleviation protein Lar zf-Sec23_Sec24 PF04810.10 EIE84988.1 - 0.26 10.8 2.2 4.4 6.9 0.4 2.2 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Mu-like_Com PF10122.4 EIE84988.1 - 0.36 9.9 2.2 6.3 5.9 0.0 2.1 1 1 1 2 2 2 0 Mu-like prophage protein Com TF_Zn_Ribbon PF08271.7 EIE84988.1 - 0.4 10.0 2.3 4.5 6.6 1.7 2.0 1 1 1 2 2 2 0 TFIIB zinc-binding zf-HYPF PF07503.7 EIE84988.1 - 1.4 8.3 4.7 26 4.3 3.2 2.3 1 1 0 1 1 1 0 HypF finger Ribosomal_L44 PF00935.14 EIE84988.1 - 1.5 8.8 5.5 14 5.7 3.8 2.2 1 1 0 1 1 1 0 Ribosomal protein L44 UCH PF00443.24 EIE84989.1 - 1.5e-36 125.9 0.1 2.1e-36 125.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RasGEF PF00617.14 EIE84990.1 - 2.8e-38 131.5 3.7 4.6e-36 124.3 1.8 2.2 1 1 1 2 2 2 2 RasGEF domain RasGEF_N PF00618.15 EIE84990.1 - 9.6e-05 22.4 0.2 0.0022 18.0 0.1 2.5 2 0 0 2 2 2 1 RasGEF N-terminal motif Aldedh PF00171.17 EIE84993.1 - 8.5e-66 222.1 0.0 1e-57 195.5 0.0 2.0 2 0 0 2 2 2 2 Aldehyde dehydrogenase family 2Fe-2S_thioredx PF01257.14 EIE84997.1 - 1.6e-58 196.4 0.1 2e-58 196.0 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin SWIRM PF04433.12 EIE84998.1 - 1.7e-08 34.4 0.0 3.5e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain RhoGAP PF00620.22 EIE84999.1 - 1.5e-48 164.3 0.1 4.3e-48 162.7 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain PH_9 PF15410.1 EIE84999.1 - 2.9e-14 53.2 0.1 7.7e-14 51.8 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain RasGEF PF00617.14 EIE84999.1 - 1.7e-07 31.1 0.9 2.2e-06 27.5 0.2 2.9 2 1 0 2 2 2 1 RasGEF domain PH PF00169.24 EIE84999.1 - 4e-05 23.7 0.0 9.7e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 PH domain RasGEF PF00617.14 EIE85000.1 - 3.1e-13 49.8 0.0 8.2e-13 48.4 0.0 1.6 1 1 1 2 2 2 1 RasGEF domain Pribosyl_synth PF14572.1 EIE85001.1 - 3e-41 141.1 1.3 4.7e-40 137.2 0.9 2.1 1 1 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 EIE85001.1 - 1.6e-29 101.9 0.4 4.1e-26 90.9 0.1 3.3 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 EIE85001.1 - 0.00052 19.7 0.3 0.0057 16.3 0.2 2.6 2 1 0 2 2 2 1 Phosphoribosyl transferase domain Hepatitis_core PF00906.15 EIE85001.1 - 0.037 13.6 0.0 0.061 12.9 0.0 1.2 1 0 0 1 1 1 0 Hepatitis core antigen Oxidored_FMN PF00724.15 EIE85001.1 - 0.056 12.4 0.1 0.087 11.8 0.0 1.2 1 0 0 1 1 1 0 NADH:flavin oxidoreductase / NADH oxidase family Ribosomal_L13e PF01294.13 EIE85002.1 - 1.2e-78 262.7 6.4 1.7e-78 262.1 4.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e DUF3959 PF13105.1 EIE85002.1 - 0.074 12.3 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) Cupin_8 PF13621.1 EIE85004.1 - 8.6e-23 81.1 5.9 1.2e-22 80.6 4.1 1.3 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 EIE85004.1 - 4.7e-15 55.8 4.3 9.7e-15 54.8 0.5 2.8 2 2 1 3 3 3 1 JmjC domain, hydroxylase DLIC PF05783.6 EIE85005.1 - 1.5e-57 195.3 2.1 3.1e-41 141.5 0.0 4.1 2 1 1 3 3 3 3 Dynein light intermediate chain (DLIC) Miro PF08477.8 EIE85005.1 - 0.0078 16.7 0.0 0.09 13.2 0.0 2.5 2 1 0 2 2 2 1 Miro-like protein AAA_29 PF13555.1 EIE85005.1 - 0.01 15.3 0.1 0.024 14.1 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 EIE85005.1 - 0.016 15.2 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 EIE85005.1 - 0.033 14.5 0.0 0.061 13.6 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.1 EIE85005.1 - 0.13 12.1 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain UCR_14kD PF02271.11 EIE85006.1 - 6.4e-28 96.5 1.9 1.2e-27 95.7 1.3 1.4 1 1 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit She9_MDM33 PF05546.6 EIE85006.1 - 0.032 13.7 0.1 0.033 13.7 0.0 1.1 1 0 0 1 1 1 0 She9 / Mdm33 family Sp38 PF07354.7 EIE85006.1 - 0.087 11.4 0.0 0.1 11.2 0.0 1.2 1 0 0 1 1 1 0 Zona-pellucida-binding protein (Sp38) IncA PF04156.9 EIE85007.1 - 0.0046 16.5 0.2 0.007 15.9 0.1 1.2 1 0 0 1 1 1 1 IncA protein Mnd1 PF03962.10 EIE85007.1 - 0.17 11.5 0.8 0.25 10.9 0.6 1.1 1 0 0 1 1 1 0 Mnd1 family DDE_3 PF13358.1 EIE85008.1 - 0.00096 18.9 0.2 0.0028 17.4 0.1 1.9 1 1 0 1 1 1 1 DDE superfamily endonuclease WW PF00397.21 EIE85009.1 - 0.00088 19.0 14.5 0.00088 19.0 10.0 2.2 2 0 0 2 2 2 1 WW domain TPR_19 PF14559.1 EIE85010.1 - 2.9e-11 43.5 0.0 0.001 19.3 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 EIE85010.1 - 2.4e-10 40.0 0.1 0.44 11.3 0.0 5.6 2 2 4 6 6 6 3 Tetratricopeptide repeat Suf PF05843.9 EIE85010.1 - 6.7e-08 32.6 27.9 9.5e-07 28.8 0.1 4.4 1 1 3 4 4 3 3 Suppressor of forked protein (Suf) TPR_16 PF13432.1 EIE85010.1 - 9.3e-08 32.5 0.0 0.023 15.3 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EIE85010.1 - 5.7e-06 25.8 0.1 0.15 12.0 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 EIE85010.1 - 6.1e-06 26.0 0.5 0.15 11.9 0.0 4.1 2 1 1 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.1 EIE85010.1 - 1.2e-05 24.5 0.8 0.0047 16.0 0.0 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat PPR PF01535.15 EIE85010.1 - 1.3e-05 24.8 0.8 0.12 12.3 0.1 3.3 3 0 0 3 3 3 2 PPR repeat PPR_2 PF13041.1 EIE85010.1 - 2.3e-05 24.2 0.1 0.096 12.6 0.0 2.7 2 0 0 2 2 2 2 PPR repeat family TPR_11 PF13414.1 EIE85010.1 - 0.002 17.7 0.0 0.013 15.1 0.0 2.3 3 0 0 3 3 3 1 TPR repeat Coatomer_E PF04733.9 EIE85010.1 - 0.0026 16.9 1.9 0.013 14.6 0.0 2.7 1 1 1 3 3 3 1 Coatomer epsilon subunit TPR_6 PF13174.1 EIE85010.1 - 0.0051 17.1 0.3 22 5.7 0.0 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat PPR_3 PF13812.1 EIE85010.1 - 0.0054 16.9 0.0 1.4 9.3 0.0 2.9 2 0 0 2 2 2 1 Pentatricopeptide repeat domain TPR_17 PF13431.1 EIE85010.1 - 0.0054 16.8 0.0 8.2 6.9 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 EIE85010.1 - 0.0057 16.3 0.1 25 4.9 0.0 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 EIE85010.1 - 0.016 15.0 0.0 0.11 12.3 0.0 2.4 2 1 0 2 2 1 0 Tetratricopeptide repeat TPR_8 PF13181.1 EIE85010.1 - 0.039 13.7 0.0 30 4.6 0.0 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat Apc3 PF12895.2 EIE85010.1 - 0.051 13.7 0.0 0.21 11.7 0.0 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 PPR_1 PF12854.2 EIE85010.1 - 0.085 12.3 0.5 14 5.2 0.1 2.4 2 0 0 2 2 2 0 PPR repeat TPR_10 PF13374.1 EIE85010.1 - 0.18 11.7 0.6 8.8 6.4 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat HAT PF02184.11 EIE85010.1 - 0.23 11.2 4.7 16 5.3 0.0 4.2 4 0 0 4 4 3 0 HAT (Half-A-TPR) repeat WRKY PF03106.10 EIE85011.1 - 2.2e-05 24.2 4.3 2.2e-05 24.2 3.0 2.4 2 0 0 2 2 2 1 WRKY DNA -binding domain BAF1_ABF1 PF04684.8 EIE85011.1 - 0.57 8.9 23.6 0.046 12.5 12.9 1.7 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Metallophos PF00149.23 EIE85013.1 - 1.3e-06 27.9 10.0 9.4e-06 25.1 6.9 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EIE85013.1 - 0.13 12.0 10.0 0.44 10.3 6.9 1.9 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain zf-H2C2_2 PF13465.1 EIE85014.1 - 6.8e-16 57.6 23.4 3.7e-08 33.2 1.5 4.2 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.21 EIE85014.1 - 1.1e-14 53.7 28.9 6.9e-06 26.1 2.6 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIE85014.1 - 2.1e-09 37.0 24.9 0.00054 20.1 2.0 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger HALZ PF02183.13 EIE85014.1 - 0.00018 21.1 0.9 0.57 9.9 0.2 2.5 2 0 0 2 2 2 2 Homeobox associated leucine zipper zf-H2C2_5 PF13909.1 EIE85014.1 - 0.00033 20.7 24.2 0.023 14.9 3.5 3.7 3 0 0 3 3 3 2 C2H2-type zinc-finger domain TPR_MLP1_2 PF07926.7 EIE85014.1 - 0.0029 17.3 2.3 0.0029 17.3 1.6 1.9 2 0 0 2 2 2 1 TPR/MLP1/MLP2-like protein zf-C2H2_6 PF13912.1 EIE85014.1 - 0.023 14.5 15.7 0.77 9.7 0.4 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger C1_4 PF07975.7 EIE85014.1 - 0.043 13.8 15.2 0.69 9.9 0.2 3.5 2 1 1 3 3 3 0 TFIIH C1-like domain Mto2_bdg PF12808.2 EIE85014.1 - 0.097 12.7 1.3 1.3 9.1 0.1 2.7 2 1 1 3 3 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Zn_Tnp_IS1595 PF12760.2 EIE85014.1 - 0.14 11.9 11.6 0.15 11.9 2.3 2.5 2 0 0 2 2 2 0 Transposase zinc-ribbon domain GAGA PF09237.6 EIE85014.1 - 0.18 11.4 5.8 4.5 6.9 1.3 2.8 1 1 1 2 2 2 0 GAGA factor Zn-ribbon_8 PF09723.5 EIE85014.1 - 0.46 10.4 12.3 6.2 6.8 3.4 3.4 1 1 3 4 4 4 0 Zinc ribbon domain bZIP_1 PF00170.16 EIE85014.1 - 0.65 9.9 7.8 0.52 10.3 0.6 3.1 2 1 1 3 3 3 0 bZIP transcription factor Phage_GP20 PF06810.6 EIE85014.1 - 1.1 8.7 5.7 0.077 12.4 0.4 1.6 2 0 0 2 2 2 0 Phage minor structural protein GP20 zf-C2H2_jaz PF12171.3 EIE85014.1 - 1.5 9.0 17.3 3.4 7.9 2.6 3.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-HIT PF04438.11 EIE85014.1 - 2.7 7.7 11.2 1.6 8.4 0.6 3.2 3 0 0 3 3 3 0 HIT zinc finger zf-AN1 PF01428.11 EIE85014.1 - 4.1 7.3 19.1 2 8.3 0.5 3.5 1 1 2 3 3 3 0 AN1-like Zinc finger zinc_ribbon_4 PF13717.1 EIE85014.1 - 6.5 6.5 9.9 28 4.5 0.5 3.4 3 0 0 3 3 3 0 zinc-ribbon domain A2L_zn_ribbon PF08792.5 EIE85014.1 - 6.5 6.3 8.2 15 5.2 0.1 3.3 3 0 0 3 3 3 0 A2L zinc ribbon domain KilA-N PF04383.8 EIE85016.1 - 0.0011 18.6 0.0 0.0051 16.4 0.0 2.1 1 1 0 1 1 1 1 KilA-N domain Innate_immun PF12782.2 EIE85016.1 - 1.4 8.0 9.7 0.11 11.7 1.2 2.1 2 0 0 2 2 2 0 Invertebrate innate immunity transcript family Pkinase PF00069.20 EIE85017.1 - 4.2e-48 163.7 0.4 3.9e-42 144.1 0.0 3.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIE85017.1 - 8.5e-19 67.6 0.0 6.2e-17 61.5 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EIE85017.1 - 0.0013 18.5 0.0 0.0023 17.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EIE85017.1 - 0.0014 17.9 0.0 0.004 16.5 0.0 1.7 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 EIE85017.1 - 0.027 13.5 0.5 0.076 12.0 0.0 1.9 1 1 1 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family HMG_box PF00505.14 EIE85018.1 - 8.4e-15 54.7 0.5 8.4e-15 54.7 0.4 2.3 3 0 0 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EIE85018.1 - 2.9e-09 37.1 0.5 2.9e-09 37.1 0.3 2.3 2 1 0 2 2 2 1 HMG-box domain Syntaxin_2 PF14523.1 EIE85018.1 - 0.0022 17.9 2.8 0.0022 17.9 2.0 2.1 2 1 0 2 2 2 1 Syntaxin-like protein TROVE PF05731.6 EIE85018.1 - 0.71 8.5 7.2 0.93 8.1 5.0 1.1 1 0 0 1 1 1 0 TROVE domain RRM_6 PF14259.1 EIE85019.1 - 2e-10 40.5 0.0 3.9e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EIE85019.1 - 2.3e-09 36.7 0.0 4.4e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE85019.1 - 6e-07 29.2 0.1 1.4e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MAP65_ASE1 PF03999.7 EIE85019.1 - 0.17 10.4 9.6 0.21 10.1 6.6 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) PCI PF01399.22 EIE85020.1 - 1e-10 41.8 0.1 1.5e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 PCI domain Alveol-reg_P311 PF11092.3 EIE85020.1 - 0.087 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Neuronal protein 3.1 (p311) CDC37_M PF08565.6 EIE85021.1 - 7.4e-35 119.9 3.6 7.4e-35 119.9 2.5 2.0 1 1 1 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_N PF03234.9 EIE85021.1 - 6.1e-32 111.3 12.8 6.1e-32 111.3 8.9 2.6 2 1 1 3 3 3 1 Cdc37 N terminal kinase binding Histone PF00125.19 EIE85021.1 - 1.4e-30 105.2 0.4 3.5e-30 103.9 0.2 1.8 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CDC37_C PF08564.5 EIE85021.1 - 2.6e-13 49.6 0.1 2.6e-13 49.6 0.1 3.2 3 0 0 3 3 3 1 Cdc37 C terminal domain CENP-S PF15630.1 EIE85021.1 - 6.4e-05 23.0 0.3 0.00024 21.2 0.0 2.1 2 0 0 2 2 2 1 Kinetochore component CENP-S Bromo_TP PF07524.8 EIE85021.1 - 0.053 13.2 0.2 0.38 10.5 0.0 2.5 2 0 0 2 2 2 0 Bromodomain associated CBFD_NFYB_HMF PF00808.18 EIE85021.1 - 0.16 12.0 0.0 0.16 12.0 0.0 3.1 3 0 0 3 3 3 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone NPV_P10 PF05531.7 EIE85021.1 - 2.4 8.4 7.2 0.92 9.8 0.2 3.0 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein LEDGF PF11467.3 EIE85023.1 - 0.089 12.5 0.1 0.11 12.2 0.1 1.3 1 1 0 1 1 1 0 Lens epithelium-derived growth factor (LEDGF) Ras PF00071.17 EIE85024.1 - 1.6e-48 164.1 0.4 1.8e-48 163.9 0.3 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIE85024.1 - 3e-18 66.4 0.1 4.2e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIE85024.1 - 4.6e-10 38.9 0.0 5.1e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EIE85024.1 - 2.2e-08 33.7 0.2 1e-07 31.5 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EIE85024.1 - 1.1e-05 24.8 0.1 4.9e-05 22.6 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.18 EIE85024.1 - 2.3e-05 24.3 0.0 2.8e-05 24.0 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EIE85024.1 - 0.0032 16.7 0.1 0.0047 16.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_14 PF13173.1 EIE85024.1 - 0.0039 17.0 0.1 0.0067 16.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EIE85024.1 - 0.012 15.2 0.1 0.014 15.1 0.1 1.5 1 1 0 1 1 1 0 Archaeal ATPase ArgK PF03308.11 EIE85024.1 - 0.023 13.4 0.0 1.8 7.2 0.0 2.3 2 0 0 2 2 2 0 ArgK protein IF3_N PF05198.11 EIE85024.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Translation initiation factor IF-3, N-terminal domain Retrotrans_gag PF03732.12 EIE85025.1 - 2.8e-05 24.0 0.5 0.00012 22.0 0.0 2.2 3 0 0 3 3 3 1 Retrotransposon gag protein DUF1664 PF07889.7 EIE85025.1 - 0.2 11.4 2.9 0.29 10.9 0.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DDE_3 PF13358.1 EIE85026.1 - 1.3e-06 28.1 0.1 1.5e-06 27.9 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease TBCA PF02970.11 EIE85026.1 - 0.054 13.5 0.3 0.097 12.7 0.1 1.5 2 0 0 2 2 2 0 Tubulin binding cofactor A Toxin_67 PF15545.1 EIE85026.1 - 0.063 13.1 1.0 0.13 12.1 0.7 1.6 1 0 0 1 1 1 0 Putative toxin 67 Pkinase PF00069.20 EIE85027.1 - 1.3e-54 185.1 0.0 1.8e-54 184.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE85027.1 - 3.7e-25 88.4 0.0 4.6e-25 88.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EIE85027.1 - 2.2e-05 23.4 0.0 3.9e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Kinase-like PF14531.1 EIE85027.1 - 0.0066 15.4 0.0 0.014 14.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EIE85027.1 - 0.041 12.9 0.0 0.071 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cadherin-like PF12733.2 EIE85029.1 - 0.0081 16.4 0.4 0.13 12.5 0.0 2.4 2 1 0 2 2 2 1 Cadherin-like beta sandwich domain Pkinase PF00069.20 EIE85030.1 - 4.2e-70 235.8 0.0 5.6e-70 235.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE85030.1 - 2.9e-39 134.7 0.0 4e-39 134.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE85030.1 - 0.0024 16.8 0.0 0.0046 15.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like AAA_18 PF13238.1 EIE85031.1 - 0.00095 19.4 0.4 0.00095 19.4 0.3 2.3 2 0 0 2 2 2 1 AAA domain PRK PF00485.13 EIE85031.1 - 0.057 12.9 1.3 0.38 10.2 0.0 2.1 1 1 1 2 2 2 0 Phosphoribulokinase / Uridine kinase family Ribosomal_L22 PF00237.14 EIE85033.1 - 5.9e-34 116.1 0.1 8.3e-34 115.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Ribosomal_L15e PF00827.12 EIE85034.1 - 7.4e-90 299.6 12.3 8.5e-90 299.4 8.5 1.0 1 0 0 1 1 1 1 Ribosomal L15 Coprogen_oxidas PF01218.13 EIE85035.1 - 2.2e-132 440.1 0.1 2.6e-132 439.8 0.1 1.1 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Hydantoinase_B PF02538.9 EIE85036.1 - 1.5e-194 647.1 0.1 2e-194 646.7 0.1 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 EIE85036.1 - 1.2e-92 310.0 4.3 1.6e-92 309.7 0.0 3.0 4 0 0 4 4 4 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EIE85036.1 - 2e-56 190.2 0.7 3e-54 183.1 0.0 2.4 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region WD40 PF00400.27 EIE85036.1 - 3e-10 39.5 1.6 7e-05 22.5 0.0 4.8 4 0 0 4 4 4 2 WD domain, G-beta repeat DivIC PF04977.10 EIE85037.1 - 0.0045 16.4 1.1 0.009 15.4 0.8 1.4 1 0 0 1 1 1 1 Septum formation initiator DUF4164 PF13747.1 EIE85037.1 - 0.0074 16.3 2.0 1.1 9.4 0.9 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4164) SlyX PF04102.7 EIE85037.1 - 0.033 14.5 1.0 0.033 14.5 0.7 1.7 2 0 0 2 2 2 0 SlyX Rab5-bind PF09311.6 EIE85037.1 - 0.039 13.8 0.3 0.07 13.0 0.2 1.3 1 0 0 1 1 1 0 Rabaptin-like protein TMF_TATA_bd PF12325.3 EIE85037.1 - 0.13 11.9 0.2 0.24 11.1 0.1 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Gag_spuma PF03276.9 EIE85037.1 - 0.19 10.0 7.8 0.24 9.6 5.4 1.1 1 0 0 1 1 1 0 Spumavirus gag protein NAD_binding_10 PF13460.1 EIE85038.1 - 2.5e-11 43.9 0.0 3.6e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EIE85038.1 - 1.2e-09 37.8 0.0 1.8e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 EIE85038.1 - 0.0014 17.3 0.3 0.0085 14.8 0.1 2.1 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family FMO-like PF00743.14 EIE85039.1 - 3.9e-40 137.5 0.0 2.6e-30 105.1 0.0 2.0 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EIE85039.1 - 4.3e-15 56.3 0.0 6.9e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EIE85039.1 - 5.2e-08 32.1 0.2 3.9e-07 29.2 0.1 2.3 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EIE85039.1 - 0.00025 20.9 0.0 0.00035 20.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EIE85039.1 - 0.15 12.1 0.1 0.58 10.2 0.1 2.0 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Bax1-I PF01027.15 EIE85040.1 - 6.3e-50 169.6 25.4 7.4e-50 169.4 17.6 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF4401 PF14351.1 EIE85040.1 - 0.0064 15.5 17.6 0.0091 15.0 12.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4401) DUF4233 PF14017.1 EIE85040.1 - 0.27 11.1 13.6 0.87 9.5 3.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF4233) Crystall PF00030.14 EIE85041.1 - 0.017 15.0 0.6 4.2 7.3 0.0 2.1 1 1 1 2 2 2 0 Beta/Gamma crystallin Porin_3 PF01459.17 EIE85042.1 - 1.3e-36 126.3 2.3 1.1e-25 90.5 0.1 2.0 1 1 1 2 2 2 2 Eukaryotic porin Autotransporter PF03797.14 EIE85042.1 - 0.056 12.7 0.1 0.078 12.3 0.1 1.2 1 0 0 1 1 1 0 Autotransporter beta-domain DUF89 PF01937.14 EIE85043.1 - 8.6e-112 373.4 6.2 9.8e-112 373.2 4.3 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 DUF4445 PF14574.1 EIE85043.1 - 0.075 11.2 0.0 0.15 10.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4445) WD40 PF00400.27 EIE85044.1 - 6.8e-15 54.2 9.7 0.00074 19.3 0.2 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat PQQ_3 PF13570.1 EIE85044.1 - 0.087 13.1 0.2 5.1 7.5 0.0 3.2 3 0 0 3 3 3 0 PQQ-like domain Peptidase_S64 PF08192.6 EIE85044.1 - 0.15 10.3 6.1 0.2 9.9 4.3 1.1 1 0 0 1 1 1 0 Peptidase family S64 CDC45 PF02724.9 EIE85045.1 - 0.047 11.7 13.8 0.077 11.0 9.6 1.3 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 EIE85045.1 - 0.35 9.3 36.5 0.65 8.4 25.3 1.4 1 0 0 1 1 1 0 Daxx Family NOA36 PF06524.7 EIE85045.1 - 4.4 6.4 10.5 7.8 5.6 7.3 1.3 1 0 0 1 1 1 0 NOA36 protein GSIII_N PF12437.3 EIE85046.1 - 1e-67 226.6 0.1 1.8e-67 225.8 0.1 1.3 1 0 0 1 1 1 1 Glutamine synthetase type III N terminal Gln-synt_C PF00120.19 EIE85046.1 - 8.3e-38 130.0 0.0 1.4e-37 129.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Rep_fac-A_C PF08646.5 EIE85047.1 - 8.8e-31 106.5 0.6 1.6e-30 105.7 0.4 1.4 1 0 0 1 1 1 1 Replication factor-A C terminal domain Rep-A_N PF04057.7 EIE85047.1 - 1.1e-15 57.3 0.0 2.1e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain zinc-ribbons_6 PF07191.7 EIE85047.1 - 0.015 15.0 3.1 0.033 13.9 2.1 1.5 1 0 0 1 1 1 0 zinc-ribbons DZR PF12773.2 EIE85047.1 - 0.037 13.8 0.6 0.075 12.8 0.4 1.4 1 0 0 1 1 1 0 Double zinc ribbon DUF1664 PF07889.7 EIE85048.1 - 5.8 6.7 13.0 0.68 9.7 4.5 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Septin PF00735.13 EIE85049.1 - 1.6e-108 362.0 1.0 2e-108 361.6 0.7 1.1 1 0 0 1 1 1 1 Septin GTP_EFTU PF00009.22 EIE85049.1 - 1.2e-07 31.3 0.0 1.8e-06 27.5 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EIE85049.1 - 3.9e-06 26.8 0.0 5.8e-06 26.2 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 EIE85049.1 - 2.2e-05 24.0 0.0 3.8e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family DUF258 PF03193.11 EIE85049.1 - 9.2e-05 21.6 0.0 0.00024 20.3 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EIE85049.1 - 0.00022 21.3 0.0 0.0014 18.7 0.0 2.1 2 1 0 2 2 2 1 AAA domain Pox_A32 PF04665.7 EIE85049.1 - 0.00034 19.9 0.0 0.00068 19.0 0.0 1.4 1 0 0 1 1 1 1 Poxvirus A32 protein Miro PF08477.8 EIE85049.1 - 0.00036 21.0 0.3 0.0012 19.2 0.2 2.0 1 1 0 1 1 1 1 Miro-like protein Dynamin_N PF00350.18 EIE85049.1 - 0.00052 19.8 0.4 0.68 9.7 0.0 2.5 1 1 1 2 2 2 2 Dynamin family T2SE PF00437.15 EIE85049.1 - 0.00072 18.5 0.0 0.0013 17.7 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_24 PF13479.1 EIE85049.1 - 0.002 17.7 0.0 0.0035 16.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EIE85049.1 - 0.0021 17.5 0.1 0.0031 17.0 0.1 1.7 1 1 0 1 1 1 1 AAA-like domain RNA_helicase PF00910.17 EIE85049.1 - 0.0022 18.1 0.0 0.0064 16.6 0.0 1.8 1 0 0 1 1 1 1 RNA helicase IIGP PF05049.8 EIE85049.1 - 0.0026 16.6 0.0 0.0044 15.9 0.0 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) MobB PF03205.9 EIE85049.1 - 0.0085 15.7 0.1 0.015 14.9 0.1 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AIG1 PF04548.11 EIE85049.1 - 0.0099 14.9 0.0 0.02 14.0 0.0 1.5 1 0 0 1 1 1 1 AIG1 family AAA_32 PF13654.1 EIE85049.1 - 0.015 13.9 0.0 0.026 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EIE85049.1 - 0.018 14.9 0.0 0.041 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EIE85049.1 - 0.018 15.3 0.0 0.036 14.3 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 EIE85049.1 - 0.021 14.3 0.0 0.04 13.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 EIE85049.1 - 0.022 14.7 0.0 0.056 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Myosin_head PF00063.16 EIE85049.1 - 0.025 12.6 0.1 0.052 11.5 0.0 1.5 2 0 0 2 2 2 0 Myosin head (motor domain) TrwB_AAD_bind PF10412.4 EIE85049.1 - 0.028 13.0 0.1 0.044 12.4 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF3987 PF13148.1 EIE85049.1 - 0.033 12.7 0.0 0.056 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) DEAD PF00270.24 EIE85049.1 - 0.035 13.5 0.0 0.05 13.0 0.0 1.3 1 0 0 1 1 1 0 DEAD/DEAH box helicase DUF2075 PF09848.4 EIE85049.1 - 0.04 12.8 0.0 0.059 12.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_21 PF13304.1 EIE85049.1 - 0.042 13.8 0.1 0.094 12.6 0.0 1.6 2 0 0 2 2 1 0 AAA domain DUF87 PF01935.12 EIE85049.1 - 0.044 13.6 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA_23 PF13476.1 EIE85049.1 - 0.045 14.0 4.7 0.16 12.3 3.3 2.0 1 1 0 1 1 1 0 AAA domain PRK PF00485.13 EIE85049.1 - 0.045 13.3 0.0 0.082 12.4 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family NACHT PF05729.7 EIE85049.1 - 0.058 13.0 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Mg_chelatase PF01078.16 EIE85049.1 - 0.067 12.3 0.0 0.29 10.2 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Ras PF00071.17 EIE85049.1 - 0.09 12.1 0.2 0.23 10.8 0.1 1.7 1 1 0 1 1 1 0 Ras family PduV-EutP PF10662.4 EIE85049.1 - 0.1 12.0 0.5 0.98 8.9 0.3 2.4 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Sigma54_activat PF00158.21 EIE85049.1 - 0.13 11.7 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Beta_elim_lyase PF01212.16 EIE85050.1 - 7.6e-70 235.3 0.0 9.2e-70 235.0 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 EIE85050.1 - 1.1e-07 31.1 0.0 2.1e-07 30.2 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EIE85050.1 - 0.036 13.1 0.0 0.11 11.5 0.0 1.7 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 EIE85050.1 - 0.037 12.3 0.0 0.057 11.6 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme MFS_1 PF07690.11 EIE85051.1 - 2.3e-12 46.2 32.0 2.3e-12 46.2 22.2 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 EIE85051.1 - 6.5e-10 38.7 2.7 6.5e-10 38.7 1.8 2.1 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 DUF2370 PF10176.4 EIE85051.1 - 0.065 12.5 4.8 0.078 12.2 0.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2370) DDE_3 PF13358.1 EIE85052.1 - 5.9e-13 48.7 0.0 6.4e-13 48.6 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease MMR_HSR1 PF01926.18 EIE85054.1 - 3.3e-10 39.9 0.4 2.8e-08 33.7 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EIE85054.1 - 0.00032 19.9 0.1 0.01 15.1 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EIE85054.1 - 0.0047 16.7 9.8 0.065 13.0 0.1 3.4 3 0 0 3 3 3 2 Dynamin family AIG1 PF04548.11 EIE85054.1 - 0.02 13.9 0.1 0.02 13.9 0.0 2.1 2 0 0 2 2 2 0 AIG1 family PEX11 PF05648.9 EIE85054.1 - 0.035 13.3 0.3 0.084 12.1 0.2 1.6 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) Miro PF08477.8 EIE85054.1 - 0.13 12.7 0.0 0.13 12.7 0.0 2.8 3 1 2 5 5 5 0 Miro-like protein SAPS PF04499.10 EIE85054.1 - 5 5.6 14.8 0.12 10.9 5.7 1.4 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein zf-CCCH PF00642.19 EIE85055.1 - 3.8e-11 42.3 19.4 4.5e-07 29.3 1.7 2.7 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 EIE85055.1 - 3.9e-06 26.6 0.0 6.5e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EIE85055.1 - 0.00035 20.1 0.0 0.00062 19.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CART PF06373.6 EIE85055.1 - 0.053 13.4 1.6 1 9.3 0.2 2.4 2 0 0 2 2 2 0 Cocaine and amphetamine regulated transcript protein (CART) Ctr PF04145.10 EIE85056.1 - 2.8e-26 92.2 0.1 3.7e-26 91.9 0.0 1.1 1 0 0 1 1 1 1 Ctr copper transporter family PMI_typeI PF01238.16 EIE85057.1 - 7.8e-128 426.5 0.0 9.8e-128 426.2 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.6 EIE85057.1 - 0.039 13.4 0.0 11 5.5 0.0 2.3 2 0 0 2 2 2 0 Cupin domain peroxidase PF00141.18 EIE85059.1 - 1.1e-26 93.6 0.0 1.9e-26 93.0 0.0 1.3 1 0 0 1 1 1 1 Peroxidase DUF4366 PF14283.1 EIE85059.1 - 0.015 14.7 0.1 0.024 14.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF2841 PF11001.3 EIE85060.1 - 0.17 11.7 5.5 0.068 13.0 0.7 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF2841) DDE_3 PF13358.1 EIE85062.1 - 4.6e-17 62.1 0.2 1.2e-15 57.5 0.0 2.2 1 1 0 2 2 2 1 DDE superfamily endonuclease DUF4240 PF14024.1 EIE85062.1 - 0.069 13.0 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4240) Aminotran_1_2 PF00155.16 EIE85063.1 - 3.4e-61 207.1 0.0 4.2e-61 206.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EIE85063.1 - 3.4e-05 23.1 0.0 7.5e-05 22.0 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase OKR_DC_1 PF01276.15 EIE85063.1 - 0.0042 15.6 0.0 0.0093 14.5 0.0 1.5 1 1 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Ten1_2 PF15490.1 EIE85063.1 - 0.015 14.8 0.0 0.036 13.6 0.0 1.5 1 0 0 1 1 1 0 Telomere-capping, CST complex subunit Ins134_P3_kin PF05770.6 EIE85063.1 - 0.11 11.5 0.0 0.25 10.2 0.0 1.6 1 0 0 1 1 1 0 Inositol 1, 3, 4-trisphosphate 5/6-kinase Methyltransf_11 PF08241.7 EIE85064.1 - 9.5e-15 54.8 0.0 3.6e-14 53.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIE85064.1 - 9.9e-15 54.4 0.0 3.6e-14 52.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIE85064.1 - 1.7e-11 44.3 0.0 3.5e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIE85064.1 - 7.2e-11 42.0 0.0 1.2e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIE85064.1 - 3.3e-10 39.4 0.0 1.7e-08 33.8 0.0 2.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EIE85064.1 - 2.3e-08 34.4 0.0 5.6e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIE85064.1 - 2.7e-07 31.1 0.0 1.1e-06 29.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EIE85064.1 - 3.3e-06 26.8 0.0 5.8e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase CMAS PF02353.15 EIE85064.1 - 2.7e-05 23.3 0.0 6.5e-05 22.1 0.0 1.6 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.12 EIE85064.1 - 4.6e-05 22.5 0.0 0.00013 21.0 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_2 PF00891.13 EIE85064.1 - 0.00043 19.5 0.0 0.00059 19.1 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_26 PF13659.1 EIE85064.1 - 0.0089 16.0 0.0 0.026 14.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain DOT1 PF08123.8 EIE85064.1 - 0.0094 15.2 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 MTS PF05175.9 EIE85064.1 - 0.012 14.9 0.0 0.021 14.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain FtsJ PF01728.14 EIE85064.1 - 0.033 14.1 0.0 0.069 13.1 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_9 PF08003.6 EIE85064.1 - 0.037 12.7 0.0 0.059 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) MetW PF07021.7 EIE85064.1 - 0.063 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW TehB PF03848.9 EIE85064.1 - 0.077 12.1 0.0 0.57 9.3 0.0 2.3 2 1 0 2 2 2 0 Tellurite resistance protein TehB BCDHK_Adom3 PF10436.4 EIE85065.1 - 1.2e-39 135.4 0.0 3.1e-39 134.1 0.0 1.7 1 1 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EIE85065.1 - 9.7e-13 47.8 0.0 1.9e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EIE85065.1 - 0.00014 21.5 0.0 0.00022 20.8 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HLH PF00010.21 EIE85066.1 - 2.4e-12 46.3 0.5 2.4e-12 46.3 0.4 1.9 2 1 1 3 3 3 1 Helix-loop-helix DNA-binding domain Glyco_hydro_20b PF02838.10 EIE85066.1 - 0.058 13.9 1.3 0.11 13.0 0.8 1.6 1 1 0 1 1 1 0 Glycosyl hydrolase family 20, domain 2 DUF572 PF04502.8 EIE85066.1 - 0.087 12.0 12.1 0.11 11.7 8.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) AAA_27 PF13514.1 EIE85066.1 - 3.7 5.1 17.8 1.8 6.1 1.5 2.1 1 1 1 2 2 2 0 AAA domain ADIP PF11559.3 EIE85067.1 - 0.0034 17.2 17.7 0.0034 17.2 12.3 3.3 3 0 0 3 3 3 2 Afadin- and alpha -actinin-Binding CCDC92 PF14916.1 EIE85067.1 - 0.011 15.3 1.2 0.011 15.3 0.9 4.1 4 0 0 4 4 4 0 Coiled-coil domain of unknown function ATG16 PF08614.6 EIE85067.1 - 0.077 12.8 35.3 0.037 13.8 8.3 3.4 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) Fib_alpha PF08702.5 EIE85067.1 - 2.1 8.4 32.2 1.7 8.7 2.5 3.3 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family DUF3275 PF11679.3 EIE85067.1 - 5.4 6.5 11.0 9.7 5.7 0.0 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF3275) DUF641 PF04859.7 EIE85067.1 - 6.3 6.5 23.6 0.56 9.9 5.3 3.4 3 1 0 3 3 3 0 Plant protein of unknown function (DUF641) QRPTase_C PF01729.14 EIE85068.1 - 2.3e-46 157.4 0.0 5e-46 156.3 0.0 1.5 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 EIE85068.1 - 3.4e-23 81.2 0.0 6.3e-23 80.4 0.0 1.5 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain Arrestin_N PF00339.24 EIE85069.1 - 5.3e-09 36.0 0.4 3.7e-06 26.8 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain RrnaAD PF00398.15 EIE85070.1 - 1e-36 126.3 0.1 2.9e-36 124.8 0.1 1.7 1 1 0 1 1 1 1 Ribosomal RNA adenine dimethylase BROMI PF14961.1 EIE85070.1 - 0.0034 14.6 0.1 0.0047 14.1 0.0 1.1 1 0 0 1 1 1 1 Broad-minded protein Methyltransf_23 PF13489.1 EIE85070.1 - 0.069 12.8 0.0 0.13 11.9 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain MinC_N PF05209.8 EIE85070.1 - 0.092 12.5 0.0 3.4 7.4 0.0 2.3 2 0 0 2 2 2 0 Septum formation inhibitor MinC, N-terminal domain NAD_Gly3P_dh_C PF07479.9 EIE85071.1 - 2e-53 180.0 0.3 1.1e-52 177.7 0.2 2.0 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.18 EIE85071.1 - 1.4e-50 171.1 0.1 4.7e-50 169.3 0.0 1.8 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.12 EIE85071.1 - 3.2e-05 24.2 1.2 0.00054 20.3 0.9 2.3 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent CoA_binding PF02629.14 EIE85071.1 - 0.048 14.1 0.5 1.4 9.4 0.1 2.4 2 0 0 2 2 2 0 CoA binding domain Semialdhyde_dh PF01118.19 EIE85071.1 - 0.084 13.1 0.0 0.23 11.7 0.0 1.8 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain TPR_12 PF13424.1 EIE85073.1 - 7.7e-05 22.5 1.1 0.0092 15.8 0.3 3.0 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 EIE85073.1 - 0.00071 19.1 0.6 0.0019 17.7 0.2 1.8 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 EIE85073.1 - 0.0025 17.3 0.8 0.89 9.2 0.8 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EIE85073.1 - 0.0076 16.0 4.9 2.1 8.4 1.1 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EIE85073.1 - 0.029 14.9 1.3 11 7.0 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 EIE85073.1 - 0.3 11.8 3.0 1.8 9.3 1.6 2.6 3 1 0 3 3 3 0 Tetratricopeptide repeat Cohesin_load PF10345.4 EIE85073.1 - 0.3 9.2 3.3 0.74 7.9 0.3 2.0 1 1 0 2 2 2 0 Cohesin loading factor MFS_1_like PF12832.2 EIE85075.1 - 4.2e-13 48.8 0.2 4.2e-13 48.8 0.1 2.6 2 0 0 2 2 2 1 MFS_1 like family ECH_C PF13766.1 EIE85078.1 - 5.7e-27 94.2 0.0 1.2e-26 93.1 0.0 1.4 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 EIE85078.1 - 4.9e-26 91.3 0.0 6.9e-26 90.8 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 EIE85079.1 - 4.7e-31 107.3 0.3 2.9e-30 104.8 0.0 2.3 3 0 0 3 3 3 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 EIE85079.1 - 8.2e-18 64.4 0.0 1.7e-16 60.0 0.0 2.0 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family FliG_N PF14842.1 EIE85079.1 - 0.045 13.8 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 FliG N-terminal domain zf-UBP PF02148.14 EIE85080.1 - 7.5e-20 70.8 5.8 7.5e-20 70.8 4.0 2.1 2 0 0 2 2 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 EIE85080.1 - 1.2e-09 37.8 10.3 1.2e-09 37.8 7.2 2.7 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 EIE85080.1 - 3e-06 27.2 5.8 3e-06 27.2 4.0 2.6 2 0 0 2 2 2 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EIE85080.1 - 8.8e-06 25.4 3.4 8.8e-06 25.4 2.4 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger BRAP2 PF07576.7 EIE85080.1 - 4e-05 23.1 0.2 0.00043 19.8 0.0 2.2 1 1 1 2 2 2 1 BRCA1-associated protein 2 zf-C3HC4_3 PF13920.1 EIE85080.1 - 6.4e-05 22.5 17.0 0.00086 18.9 4.9 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIE85080.1 - 0.00012 21.6 9.5 0.00012 21.6 6.6 3.3 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIE85080.1 - 0.00022 20.8 8.8 0.00022 20.8 6.1 2.7 2 1 0 2 2 2 1 zinc-RING finger domain ArfGap PF01412.13 EIE85080.1 - 0.0033 17.1 0.4 0.008 15.9 0.3 1.7 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf zf-C3HC4_2 PF13923.1 EIE85080.1 - 0.017 15.0 10.1 0.017 15.0 7.0 2.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EIE85080.1 - 4 7.2 19.1 0.087 12.5 1.9 3.8 4 0 0 4 4 4 0 RING-type zinc-finger EF1_GNE PF00736.14 EIE85081.1 - 6.4e-32 109.1 0.6 1.2e-31 108.2 0.4 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 EIE85081.1 - 1.2e-13 50.8 4.4 1.2e-13 50.8 3.0 2.7 3 1 0 3 3 3 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.1 EIE85081.1 - 0.0006 20.2 0.0 0.0013 19.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain KCl_Cotrans_1 PF03522.10 EIE85081.1 - 1.1 8.7 3.9 0.57 9.7 0.2 2.3 2 0 0 2 2 2 0 K-Cl Co-transporter type 1 (KCC1) 5-FTHF_cyc-lig PF01812.15 EIE85082.1 - 4.9e-21 75.3 0.0 9.5e-21 74.4 0.0 1.4 1 1 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Anp1 PF03452.9 EIE85082.1 - 0.14 11.2 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 Anp1 Haemolytic PF01809.13 EIE85082.1 - 0.16 11.5 0.8 0.67 9.6 0.2 2.0 1 1 1 2 2 2 0 Haemolytic domain Sec23_trunk PF04811.10 EIE85083.1 - 5.1e-72 242.1 0.0 8.4e-72 241.4 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EIE85083.1 - 2.3e-22 78.3 0.0 4.9e-22 77.3 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 EIE85083.1 - 9.4e-18 63.4 2.7 1.9e-17 62.5 1.9 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 EIE85083.1 - 9.2e-17 61.3 0.0 2.2e-16 60.1 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 EIE85083.1 - 1.6e-09 37.3 0.0 5.5e-09 35.5 0.0 2.0 2 0 0 2 2 2 1 Gelsolin repeat VWA PF00092.23 EIE85083.1 - 0.011 15.4 0.1 0.026 14.2 0.0 1.5 1 0 0 1 1 1 0 von Willebrand factor type A domain Sen15 PF09631.5 EIE85083.1 - 0.031 14.4 0.0 0.077 13.2 0.0 1.6 1 0 0 1 1 1 0 Sen15 protein PEX11 PF05648.9 EIE85084.1 - 1.1e-32 113.1 0.0 1.3e-32 112.8 0.0 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) PPR_2 PF13041.1 EIE85085.1 - 1.1e-43 147.0 19.1 1.8e-13 50.2 0.1 10.4 10 2 1 11 11 11 5 PPR repeat family PPR_3 PF13812.1 EIE85085.1 - 8.9e-33 109.8 8.5 3.6e-05 23.7 0.0 12.9 13 1 1 14 14 13 6 Pentatricopeptide repeat domain PPR PF01535.15 EIE85085.1 - 8.4e-30 100.6 14.9 6.9e-07 28.8 0.1 11.9 13 1 0 13 13 12 6 PPR repeat PPR_1 PF12854.2 EIE85085.1 - 2.1e-21 75.0 6.0 2.3e-05 23.7 0.0 9.6 11 0 0 11 11 11 4 PPR repeat RPM2 PF08579.6 EIE85085.1 - 0.00031 20.8 6.1 6.7 6.8 0.0 5.2 5 1 0 5 5 5 2 Mitochondrial ribonuclease P subunit (RPM2) ATP13 PF12921.2 EIE85085.1 - 0.00042 19.6 0.7 0.13 11.6 0.0 4.0 4 0 0 4 4 4 1 Mitochondrial ATPase expression TPR_14 PF13428.1 EIE85085.1 - 0.0044 17.5 0.0 12 6.8 0.0 4.9 5 0 0 5 5 4 1 Tetratricopeptide repeat ECSIT PF06239.6 EIE85085.1 - 0.0083 15.0 1.8 16 4.2 0.0 4.0 3 1 1 4 4 4 0 Evolutionarily conserved signalling intermediate in Toll pathway RPN7 PF10602.4 EIE85085.1 - 0.0085 15.4 0.6 0.21 10.9 0.1 2.6 2 0 0 2 2 2 1 26S proteasome subunit RPN7 CaMKII_AD PF08332.5 EIE85085.1 - 0.011 15.5 0.1 0.41 10.5 0.0 3.2 3 1 1 4 4 4 0 Calcium/calmodulin dependent protein kinase II Association Apc3 PF12895.2 EIE85085.1 - 0.016 15.3 8.6 19 5.4 0.0 5.4 4 1 1 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 LRR_4 PF12799.2 EIE85086.1 - 5.1e-10 38.7 3.7 0.0014 18.1 0.0 3.5 3 1 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EIE85086.1 - 9.5e-05 22.0 3.6 0.019 14.7 0.2 2.5 2 1 1 3 3 3 3 Leucine rich repeat LRR_6 PF13516.1 EIE85086.1 - 0.0024 17.7 7.3 0.78 9.9 0.0 4.0 3 2 1 4 4 4 2 Leucine Rich repeat LRR_7 PF13504.1 EIE85086.1 - 0.013 15.5 2.4 0.52 10.7 0.0 3.8 3 1 1 4 4 4 0 Leucine rich repeat Tuberin PF03542.11 EIE85086.1 - 0.052 12.5 0.1 0.06 12.3 0.1 1.1 1 0 0 1 1 1 0 Tuberin LRR_1 PF00560.28 EIE85086.1 - 0.068 13.2 2.0 8.7 6.8 0.0 3.6 2 2 1 3 3 3 0 Leucine Rich Repeat ACT_6 PF13740.1 EIE85086.1 - 0.11 12.1 0.6 0.9 9.3 0.2 2.1 1 1 1 2 2 2 0 ACT domain FA_desaturase PF00487.19 EIE85087.1 - 3.3e-27 95.5 19.4 5.6e-27 94.7 13.4 1.3 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 EIE85087.1 - 2.3e-08 34.1 0.0 4.5e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Nucleoplasmin PF03066.10 EIE85088.1 - 0.0027 17.2 4.2 0.0031 17.0 2.9 1.1 1 0 0 1 1 1 1 Nucleoplasmin Ribosomal_60s PF00428.14 EIE85088.1 - 0.073 13.4 3.9 0.086 13.2 2.7 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF1428 PF07237.6 EIE85088.1 - 0.093 12.6 0.6 0.1 12.4 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1428) Rpn3_C PF08375.6 EIE85088.1 - 0.12 12.8 3.6 0.24 11.8 2.6 1.4 1 1 0 1 1 1 0 Proteasome regulatory subunit C-terminal NOA36 PF06524.7 EIE85088.1 - 0.29 10.3 5.4 0.31 10.2 3.7 1.1 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.6 EIE85088.1 - 0.37 10.5 2.8 0.42 10.4 2.0 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF2457 PF10446.4 EIE85088.1 - 0.51 8.9 9.8 0.53 8.9 6.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.9 EIE85088.1 - 0.54 8.2 4.8 0.54 8.2 3.4 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 EIE85088.1 - 0.91 7.3 7.9 0.91 7.3 5.5 1.0 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.8 EIE85088.1 - 0.97 9.0 6.3 1.1 8.8 4.4 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region TRAP_alpha PF03896.11 EIE85088.1 - 2.6 6.9 5.5 2.9 6.7 3.8 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit PPP4R2 PF09184.6 EIE85088.1 - 5.8 6.3 9.9 6.6 6.1 6.9 1.1 1 0 0 1 1 1 0 PPP4R2 PPR_2 PF13041.1 EIE85090.1 - 3.3e-25 87.7 8.4 5.4e-12 45.4 0.2 9.2 7 2 3 10 10 10 5 PPR repeat family PPR_3 PF13812.1 EIE85090.1 - 6.9e-15 54.0 3.8 0.00093 19.2 0.0 9.9 11 0 0 11 11 11 3 Pentatricopeptide repeat domain PPR PF01535.15 EIE85090.1 - 1.4e-08 34.0 6.5 0.0011 18.7 0.0 8.3 10 0 0 10 10 10 1 PPR repeat PPR_1 PF12854.2 EIE85090.1 - 2.1e-06 27.1 6.3 0.0032 16.9 0.0 4.9 5 0 0 5 5 5 2 PPR repeat RPM2 PF08579.6 EIE85090.1 - 0.0032 17.6 0.9 0.97 9.5 0.1 3.6 2 1 0 2 2 2 1 Mitochondrial ribonuclease P subunit (RPM2) WGG PF10273.4 EIE85091.1 - 3e-29 100.9 0.5 4.8e-29 100.2 0.3 1.3 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 NOA36 PF06524.7 EIE85091.1 - 0.085 12.1 4.8 0.1 11.8 3.4 1.1 1 0 0 1 1 1 0 NOA36 protein Nucleoplasmin PF03066.10 EIE85091.1 - 0.11 11.9 4.5 0.13 11.7 3.1 1.3 1 0 0 1 1 1 0 Nucleoplasmin PBP1_TM PF14812.1 EIE85091.1 - 2.3 8.5 7.3 4.8 7.5 5.0 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ASL_C PF08328.6 EIE85092.1 - 0.02 14.7 0.0 0.068 13.0 0.0 1.9 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminal Oxidored_FMN PF00724.15 EIE85093.1 - 4.5e-103 344.8 0.0 5.1e-103 344.6 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Catalase PF00199.14 EIE85094.1 - 2.1e-200 665.3 1.3 2.6e-200 664.9 0.9 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EIE85094.1 - 1e-23 82.9 1.5 2.2e-23 81.8 0.1 2.3 3 0 0 3 3 3 1 Catalase-related immune-responsive HSP20 PF00011.16 EIE85096.1 - 1.6e-19 69.6 0.1 5.6e-18 64.6 0.0 2.1 1 1 0 1 1 1 1 Hsp20/alpha crystallin family BRCA-2_OB1 PF09103.5 EIE85097.1 - 1.2e-09 37.8 0.0 2.6e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA2 PF00634.13 EIE85098.1 - 7.4e-13 47.5 0.7 2.5e-07 29.8 0.1 3.5 3 0 0 3 3 3 2 BRCA2 repeat Skp1 PF01466.14 EIE85099.1 - 0.0076 16.2 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Pox_vIL-18BP PF05566.7 EIE85099.1 - 0.11 12.4 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Orthopoxvirus interleukin 18 binding protein DUF1848 PF08902.6 EIE85099.1 - 0.13 11.7 0.0 0.17 11.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1848) SAP PF02037.22 EIE85101.1 - 8.4e-10 37.9 0.3 1.6e-09 36.9 0.2 1.5 1 0 0 1 1 1 1 SAP domain Methyltransf_11 PF08241.7 EIE85104.1 - 1.1e-08 35.4 0.0 1.8e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIE85104.1 - 6.9e-06 25.7 0.0 8.7e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIE85104.1 - 1.2e-05 24.5 0.0 2.3e-05 23.6 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EIE85104.1 - 5.9e-05 23.3 0.0 0.00014 22.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.13 EIE85104.1 - 0.00012 21.4 0.0 0.00019 20.8 0.0 1.3 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain Methyltransf_8 PF05148.10 EIE85104.1 - 0.00051 19.7 0.0 0.00096 18.8 0.0 1.5 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_12 PF08242.7 EIE85104.1 - 0.00054 20.3 0.0 0.0009 19.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIE85104.1 - 0.012 15.3 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 EIE85104.1 - 0.045 14.3 0.0 0.075 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_29 PF03141.11 EIE85104.1 - 0.061 11.6 0.0 0.077 11.3 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_26 PF13659.1 EIE85104.1 - 0.064 13.2 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DDE_3 PF13358.1 EIE85106.1 - 1.8e-27 95.8 0.0 6.4e-27 94.0 0.0 1.9 1 1 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE85106.1 - 0.0097 16.0 0.0 0.018 15.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain DUF4240 PF14024.1 EIE85106.1 - 0.031 14.1 0.1 0.12 12.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4240) EF-hand_6 PF13405.1 EIE85107.1 - 1e-22 77.9 6.7 2.3e-06 27.0 0.2 5.0 4 1 1 5 5 5 4 EF-hand domain EF-hand_1 PF00036.27 EIE85107.1 - 6.6e-22 75.1 14.5 2e-06 26.7 0.0 4.7 5 0 0 5 5 5 3 EF hand EF-hand_7 PF13499.1 EIE85107.1 - 1.2e-21 76.6 3.8 1e-14 54.4 0.3 2.8 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EIE85107.1 - 3.5e-16 57.7 11.6 1.6e-05 23.9 0.6 4.5 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 EIE85107.1 - 2.2e-11 43.2 11.4 2.8e-05 23.6 0.7 4.0 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.2 EIE85107.1 - 3.2e-07 30.0 6.2 0.082 12.6 0.1 3.9 2 1 2 4 4 4 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EIE85107.1 - 0.0001 22.2 0.8 0.0068 16.4 0.1 2.9 2 2 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region S10_plectin PF03501.10 EIE85107.1 - 0.0097 15.7 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 Plectin/S10 domain Toprim PF01751.17 EIE85107.1 - 0.015 15.2 0.0 3.3 7.7 0.0 2.5 2 1 0 2 2 2 0 Toprim domain Toprim_2 PF13155.1 EIE85107.1 - 0.15 12.3 0.6 3.1 8.1 0.1 2.7 1 1 1 2 2 2 0 Toprim-like EF-hand_10 PF14788.1 EIE85107.1 - 0.19 11.4 2.3 14 5.4 0.0 3.9 5 0 0 5 5 5 0 EF hand Humanin PF15040.1 EIE85108.1 - 0.043 13.0 0.4 0.096 11.9 0.3 1.5 1 0 0 1 1 1 0 Humanin family p450 PF00067.17 EIE85109.1 - 1e-53 182.5 0.0 2.1e-53 181.5 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 OmdA PF13376.1 EIE85110.1 - 0.11 12.1 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated HTH_Tnp_Tc3_2 PF01498.13 EIE85111.1 - 2.3e-06 27.5 0.4 2.3e-06 27.5 0.3 1.5 2 0 0 2 2 2 1 Transposase Cyt-b5 PF00173.23 EIE85112.1 - 2e-10 40.3 0.4 2.5e-10 40.0 0.2 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Sec16_N PF12935.2 EIE85113.1 - 0.094 12.5 0.1 0.16 11.8 0.1 1.3 1 0 0 1 1 1 0 Vesicle coat trafficking protein Sec16 N-terminus Mut7-C PF01927.11 EIE85113.1 - 0.17 11.8 2.8 0.12 12.2 0.3 1.9 3 0 0 3 3 3 0 Mut7-C RNAse domain Glyco_hydro_46 PF01374.13 EIE85115.1 - 2.3e-26 92.7 0.1 2.9e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 46 Scs3p PF10261.4 EIE85116.1 - 3.7e-33 114.5 12.1 8e-33 113.4 8.4 1.5 1 1 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM PAP2 PF01569.16 EIE85116.1 - 0.022 14.4 2.2 0.026 14.2 1.5 1.2 1 0 0 1 1 1 0 PAP2 superfamily FixP_N PF14715.1 EIE85116.1 - 0.11 11.8 6.2 0.27 10.6 0.1 2.4 2 0 0 2 2 2 0 N-terminal domain of cytochrome oxidase-cbb3, FixP WD40 PF00400.27 EIE85117.1 - 2.7e-68 223.5 10.2 1.8e-10 40.2 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 EIE85117.1 - 2.3e-19 69.3 17.7 5e-11 42.6 7.6 2.3 1 1 1 2 2 2 2 Tup N-terminal Cytochrom_D1 PF02239.11 EIE85117.1 - 0.00078 17.8 0.3 0.0043 15.3 0.1 2.2 1 1 1 2 2 2 1 Cytochrome D1 heme domain Nup160 PF11715.3 EIE85117.1 - 0.00079 17.6 1.9 0.025 12.7 0.1 3.5 1 1 2 4 4 4 1 Nucleoporin Nup120/160 Nbas_N PF15492.1 EIE85117.1 - 0.0021 17.1 0.1 0.9 8.5 0.0 3.0 1 1 1 3 3 3 1 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.7 EIE85117.1 - 0.0038 16.8 0.3 2 8.1 0.0 3.8 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.6 EIE85117.1 - 0.0079 14.9 0.2 14 4.3 0.1 3.8 1 1 3 4 4 4 0 Nup133 N terminal like TMPIT PF07851.8 EIE85117.1 - 0.51 9.3 6.4 0.69 8.9 4.5 1.1 1 0 0 1 1 1 0 TMPIT-like protein THOC7 PF05615.8 EIE85117.1 - 0.62 10.3 12.9 5.2 7.3 9.0 2.0 1 1 0 1 1 1 0 Tho complex subunit 7 Mitofilin PF09731.4 EIE85117.1 - 1.3 7.5 7.3 1.8 7.1 5.1 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein VID27 PF08553.5 EIE85117.1 - 2 6.5 4.4 5.7 5.0 0.0 2.7 3 0 0 3 3 3 0 VID27 cytoplasmic protein AMP-binding PF00501.23 EIE85118.1 - 1.8e-78 263.7 0.2 2.2e-78 263.5 0.2 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EIE85118.1 - 5.9e-19 68.7 0.1 1.7e-18 67.2 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Ham1p_like PF01725.11 EIE85119.1 - 8.1e-45 152.5 0.0 8.9e-45 152.3 0.0 1.0 1 0 0 1 1 1 1 Ham1 family ER_lumen_recept PF00810.13 EIE85120.1 - 0.0046 17.4 3.4 0.0046 17.4 2.3 2.2 1 1 0 2 2 2 1 ER lumen protein retaining receptor RRM_1 PF00076.17 EIE85121.1 - 1.3e-15 56.7 0.0 2.4e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE85121.1 - 7.3e-12 45.0 0.0 1.4e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE85121.1 - 9.6e-06 25.3 0.0 1.7e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FBP PF07299.6 EIE85121.1 - 0.011 15.0 0.3 0.016 14.5 0.2 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein (FBP) STAT_alpha PF01017.15 EIE85121.1 - 0.013 15.2 0.3 0.018 14.7 0.2 1.3 1 0 0 1 1 1 0 STAT protein, all-alpha domain TBPIP PF07106.8 EIE85121.1 - 0.051 13.1 3.6 0.073 12.6 2.5 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF4140 PF13600.1 EIE85121.1 - 0.083 13.3 4.9 0.19 12.2 3.4 1.5 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Fmp27_WPPW PF10359.4 EIE85121.1 - 0.092 11.1 3.5 0.11 10.8 2.4 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain NDUF_B5 PF09781.4 EIE85121.1 - 0.16 11.1 1.0 0.24 10.6 0.7 1.2 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit DUF871 PF05913.6 EIE85121.1 - 0.26 10.0 2.0 0.32 9.7 1.4 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF871) HAP1_N PF04849.8 EIE85121.1 - 0.26 10.2 8.8 0.39 9.6 6.1 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region Phage_GP20 PF06810.6 EIE85121.1 - 0.27 10.6 9.1 0.34 10.3 6.3 1.1 1 0 0 1 1 1 0 Phage minor structural protein GP20 PA26 PF04636.8 EIE85121.1 - 0.31 9.6 1.8 0.33 9.6 1.3 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Allexi_40kDa PF05549.6 EIE85121.1 - 0.56 9.4 4.2 0.35 10.1 1.1 1.7 2 0 0 2 2 2 0 Allexivirus 40kDa protein V_ATPase_I PF01496.14 EIE85121.1 - 0.75 7.5 2.2 0.8 7.4 1.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HrpA_pilin PF09589.5 EIE85121.1 - 0.84 10.0 6.2 1.2 9.5 4.3 1.2 1 0 0 1 1 1 0 HrpA pilus formation protein IncA PF04156.9 EIE85121.1 - 0.91 9.0 4.6 1.2 8.6 3.2 1.1 1 0 0 1 1 1 0 IncA protein DUF972 PF06156.8 EIE85121.1 - 1.2 9.4 4.3 1.8 8.9 2.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF972) APG6 PF04111.7 EIE85121.1 - 1.3 8.0 5.7 1.8 7.5 4.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DivIC PF04977.10 EIE85121.1 - 3.2 7.3 6.2 1.1 8.8 2.1 1.8 1 1 1 2 2 2 0 Septum formation initiator DUF2414 PF10309.4 EIE85122.1 - 0.038 13.6 0.0 0.072 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2414) RNA_bind PF08675.6 EIE85122.1 - 0.074 13.0 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 RNA binding domain Cytochrom_C PF00034.16 EIE85123.1 - 3.6e-11 43.7 0.3 7.4e-11 42.7 0.2 1.5 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 EIE85123.1 - 2.3e-09 37.2 3.4 3.1e-08 33.6 2.3 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 EIE85123.1 - 0.00055 19.4 0.6 0.01 15.2 0.1 2.2 2 0 0 2 2 2 1 Cytochrome c-550 domain CCP_MauG PF03150.9 EIE85123.1 - 0.032 14.5 0.0 0.039 14.2 0.0 1.2 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase F-box-like PF12937.2 EIE85125.1 - 0.002 17.8 1.5 0.0051 16.5 1.1 1.7 1 1 0 1 1 1 1 F-box-like PUF PF00806.14 EIE85126.1 - 5.3e-71 230.2 12.6 1.6e-08 33.5 0.0 8.7 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat SNase PF00565.12 EIE85127.1 - 3.8e-22 78.5 0.1 5.8e-22 78.0 0.1 1.3 1 0 0 1 1 1 1 Staphylococcal nuclease homologue HTH_Tnp_Tc3_2 PF01498.13 EIE85128.1 - 4.3e-10 39.4 0.5 7.5e-10 38.7 0.4 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.1 EIE85128.1 - 0.00071 19.3 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Rab5-bind PF09311.6 EIE85129.1 - 0.015 15.1 0.6 0.026 14.3 0.4 1.3 1 0 0 1 1 1 0 Rabaptin-like protein CCDC92 PF14916.1 EIE85129.1 - 0.016 14.8 0.2 0.032 13.8 0.1 1.5 1 0 0 1 1 1 0 Coiled-coil domain of unknown function DUF904 PF06005.7 EIE85129.1 - 0.049 13.9 0.9 0.073 13.3 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Lebercilin PF15619.1 EIE85129.1 - 0.17 11.3 1.3 0.31 10.4 0.9 1.4 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease DivIC PF04977.10 EIE85129.1 - 0.25 10.8 3.0 0.26 10.8 1.2 1.6 2 0 0 2 2 2 0 Septum formation initiator DUF3847 PF12958.2 EIE85129.1 - 0.5 10.1 3.2 0.37 10.5 0.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) IL4 PF00727.13 EIE85130.1 - 0.015 15.1 0.3 0.031 14.1 0.2 1.5 1 0 0 1 1 1 0 Interleukin 4 PH PF00169.24 EIE85131.1 - 5.8e-07 29.6 2.1 1.5e-06 28.3 1.5 1.8 1 0 0 1 1 1 1 PH domain DUF2387 PF09526.5 EIE85131.1 - 0.01 15.7 0.0 0.031 14.1 0.0 1.8 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) Mcp5_PH PF12814.2 EIE85131.1 - 0.25 11.2 2.1 2.8 7.8 1.5 2.4 1 1 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology PH_11 PF15413.1 EIE85131.1 - 8.1 6.7 7.9 11 6.2 2.2 2.9 2 1 0 2 2 2 0 Pleckstrin homology domain BP28CT PF08146.7 EIE85132.1 - 7.5e-43 145.8 3.5 7.5e-43 145.8 2.4 4.5 6 0 0 6 6 6 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 EIE85132.1 - 3.9e-18 65.5 1.1 3.9e-18 65.5 0.8 6.7 9 0 0 9 9 9 1 U3 small nucleolar RNA-associated protein 10 HEAT_2 PF13646.1 EIE85132.1 - 3.5e-07 30.4 0.6 1.6 9.0 0.0 6.3 7 0 0 7 7 7 2 HEAT repeats HEAT_EZ PF13513.1 EIE85132.1 - 0.00097 19.5 5.0 0.54 10.8 0.0 6.1 4 2 3 7 7 7 1 HEAT-like repeat HEAT PF02985.17 EIE85132.1 - 0.0017 18.2 13.0 0.17 12.0 0.1 7.0 8 0 0 8 8 8 2 HEAT repeat Cellulase PF00150.13 EIE85133.1 - 1.2e-16 60.7 0.0 5.5e-12 45.4 0.0 3.2 2 2 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Hist_deacetyl PF00850.14 EIE85135.1 - 1.1e-68 231.7 0.1 1.1e-68 231.7 0.1 2.2 2 1 0 2 2 2 1 Histone deacetylase domain Pkinase PF00069.20 EIE85136.1 - 6.3e-42 143.5 0.1 7.2e-42 143.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE85136.1 - 1.7e-23 83.0 0.0 2.1e-23 82.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE85136.1 - 6.3e-05 22.0 0.0 0.001 18.0 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Pox_ser-thr_kin PF05445.6 EIE85136.1 - 0.0009 18.1 2.2 0.0015 17.4 0.9 1.8 1 1 1 2 2 2 1 Poxvirus serine/threonine protein kinase Seadorna_VP7 PF07387.6 EIE85136.1 - 0.0026 16.6 0.1 0.0054 15.6 0.1 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.18 EIE85136.1 - 0.019 14.7 0.3 0.068 12.9 0.3 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family YukC PF10140.4 EIE85136.1 - 0.11 11.1 0.1 0.13 10.8 0.0 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Kdo PF06293.9 EIE85136.1 - 0.13 11.3 0.3 0.18 10.8 0.2 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family E1-E2_ATPase PF00122.15 EIE85137.1 - 2.4e-21 75.8 0.0 4.9e-21 74.8 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 EIE85137.1 - 1.4e-14 54.7 0.1 2.8e-14 53.7 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EIE85137.1 - 4.6e-12 46.8 0.7 6.1e-11 43.1 0.5 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EIE85137.1 - 1e-11 44.6 0.0 2.7e-11 43.2 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EIE85137.1 - 0.00076 19.1 0.3 0.0045 16.6 0.2 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Arf PF00025.16 EIE85138.1 - 2.3e-47 160.4 0.2 3e-47 160.1 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EIE85138.1 - 2.3e-21 75.8 0.0 2.8e-21 75.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIE85138.1 - 4.2e-12 46.5 0.0 6.4e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 EIE85138.1 - 3e-11 42.9 0.0 3.4e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EIE85138.1 - 2e-09 36.9 0.0 2.3e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EIE85138.1 - 5e-09 35.3 0.5 6.8e-07 28.3 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.18 EIE85138.1 - 5.5e-09 36.0 0.0 8.9e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EIE85138.1 - 6.4e-07 28.9 0.1 3.2e-05 23.4 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EIE85138.1 - 0.0017 18.2 0.1 0.47 10.2 0.1 2.2 1 1 1 2 2 2 1 Dynamin family AAA_22 PF13401.1 EIE85138.1 - 0.0086 16.2 0.0 0.037 14.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain cobW PF02492.14 EIE85138.1 - 0.012 15.0 0.1 2.1 7.7 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 EIE85138.1 - 0.016 14.8 0.1 0.65 9.6 0.0 2.1 2 0 0 2 2 2 0 NACHT domain AAA PF00004.24 EIE85138.1 - 0.038 14.1 0.0 0.07 13.3 0.0 1.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EIE85138.1 - 0.067 13.0 0.0 0.16 11.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain MobB PF03205.9 EIE85138.1 - 0.08 12.6 0.2 0.21 11.2 0.1 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B FeoB_N PF02421.13 EIE85138.1 - 0.097 11.9 2.2 0.16 11.2 0.1 2.1 2 1 0 2 2 2 0 Ferrous iron transport protein B Flu_PB1 PF00602.12 EIE85139.1 - 0.14 9.8 0.1 0.15 9.7 0.1 1.0 1 0 0 1 1 1 0 Influenza RNA-dependent RNA polymerase subunit PB1 TFR_dimer PF04253.10 EIE85140.1 - 2.7e-20 72.1 0.1 4.6e-20 71.4 0.1 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 EIE85140.1 - 2.3e-19 69.7 0.0 3.9e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EIE85140.1 - 2e-05 24.2 0.0 5.3e-05 22.8 0.0 1.7 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.23 EIE85140.1 - 3.2e-05 23.5 0.0 5.9e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Snf7 PF03357.16 EIE85140.1 - 0.013 14.9 0.2 0.02 14.3 0.1 1.2 1 0 0 1 1 1 0 Snf7 Nicastrin PF05450.10 EIE85140.1 - 0.052 12.7 0.1 0.2 10.8 0.0 1.8 2 1 1 3 3 3 0 Nicastrin DUF3210 PF11489.3 EIE85140.1 - 0.28 9.8 0.2 0.41 9.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3210) AIF_C PF14721.1 EIE85142.1 - 3.2e-46 156.8 0.1 6.5e-46 155.8 0.0 1.5 1 0 0 1 1 1 1 Apoptosis-inducing factor, mitochondrion-associated, C-term Pyr_redox_2 PF07992.9 EIE85142.1 - 4.1e-26 92.1 1.0 2.3e-24 86.3 0.7 3.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EIE85142.1 - 3.1e-12 46.7 1.2 1e-09 38.6 0.1 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EIE85142.1 - 1.4e-08 34.0 3.9 0.0014 17.6 0.1 3.6 3 1 1 4 4 4 3 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EIE85142.1 - 1.1e-07 31.7 1.2 0.075 12.8 0.1 4.1 3 1 1 4 4 4 3 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EIE85142.1 - 1.5e-06 27.3 0.1 0.00031 19.8 0.0 2.7 2 1 1 3 3 3 1 Lycopene cyclase protein HI0933_like PF03486.9 EIE85142.1 - 2.5e-06 26.2 0.4 0.0058 15.1 0.0 3.0 3 0 0 3 3 3 2 HI0933-like protein K_oxygenase PF13434.1 EIE85142.1 - 3.1e-06 26.3 0.0 9.3e-05 21.4 0.0 2.3 1 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.9 EIE85142.1 - 0.054 12.1 1.1 3.2 6.2 0.1 2.7 2 1 1 3 3 3 0 Tryptophan halogenase Shikimate_DH PF01488.15 EIE85142.1 - 0.094 12.8 1.2 1.3 9.0 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.17 EIE85142.1 - 0.18 10.5 2.4 12 4.5 0.0 3.0 3 0 0 3 3 3 0 Glucose inhibited division protein A CTP_transf_2 PF01467.21 EIE85144.1 - 2e-23 83.1 0.1 4.7e-23 81.9 0.0 1.6 1 0 0 1 1 1 1 Cytidylyltransferase WD40 PF00400.27 EIE85145.1 - 2.1e-20 71.7 7.4 1.1e-06 28.3 0.1 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat eIF2A PF08662.6 EIE85145.1 - 0.0019 17.9 0.0 0.0033 17.1 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 EIE85145.1 - 0.0097 14.2 0.0 0.017 13.4 0.0 1.4 1 0 0 1 1 1 1 Cytochrome D1 heme domain Mito_fiss_reg PF05308.6 EIE85145.1 - 0.11 11.8 0.7 0.15 11.3 0.5 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF3824 PF12868.2 EIE85146.1 - 0.044 14.7 0.7 0.084 13.8 0.5 1.4 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Sec62 PF03839.11 EIE85147.1 - 4.9e-47 160.2 0.1 5.7e-47 160.0 0.1 1.2 1 0 0 1 1 1 1 Translocation protein Sec62 Tfb4 PF03850.9 EIE85148.1 - 1e-72 244.7 8.1 1.4e-45 155.7 0.0 2.0 1 1 1 2 2 2 2 Transcription factor Tfb4 Protoglobin PF11563.3 EIE85149.1 - 1.3e-42 145.0 0.0 1.6e-42 144.8 0.0 1.1 1 0 0 1 1 1 1 Protoglobin RNase_T PF00929.19 EIE85153.1 - 9e-14 52.0 0.1 1.7e-13 51.1 0.0 1.5 1 0 0 1 1 1 1 Exonuclease DYW_deaminase PF14432.1 EIE85153.1 - 0.0024 17.8 0.0 0.011 15.6 0.0 2.1 2 1 0 2 2 2 1 DYW family of nucleic acid deaminases Lipase_GDSL PF00657.17 EIE85155.1 - 1.7e-07 31.3 0.0 2e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EIE85155.1 - 0.0012 19.0 0.0 0.042 13.9 0.0 2.2 2 0 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase family Ank PF00023.25 EIE85156.1 - 3.7e-17 61.1 0.1 4.9e-08 32.3 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 EIE85156.1 - 2.8e-15 56.4 0.1 3.9e-15 55.9 0.0 1.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EIE85156.1 - 4.3e-15 54.3 0.3 2.5e-06 27.1 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EIE85156.1 - 1.8e-10 41.0 0.0 7.9e-10 38.9 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EIE85156.1 - 4.6e-10 39.4 0.2 0.00035 20.7 0.0 2.9 1 1 2 3 3 3 2 Ankyrin repeats (many copies) DDRGK PF09756.4 EIE85157.1 - 8.6e-13 48.1 29.8 8.6e-13 48.1 20.7 1.8 2 0 0 2 2 2 1 DDRGK domain HTH_Crp_2 PF13545.1 EIE85157.1 - 0.044 13.5 0.0 7.4 6.4 0.0 2.6 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain Noggin PF05806.7 EIE85157.1 - 2.2 7.4 6.7 1.1 8.5 2.9 1.7 1 1 0 1 1 1 0 Noggin CAF-1_p150 PF11600.3 EIE85157.1 - 4.1 6.7 42.1 6.3 6.1 29.2 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF1800 PF08811.6 EIE85157.1 - 7.1 5.4 10.8 9.6 4.9 7.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) DUF4661 PF15576.1 EIE85157.1 - 7.9 6.0 8.0 9.9 5.7 5.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) Utp11 PF03998.8 EIE85158.1 - 4.5e-70 236.2 38.1 5.1e-70 236.0 26.4 1.0 1 0 0 1 1 1 1 Utp11 protein Recep_L_domain PF01030.19 EIE85159.1 - 1.8e-07 31.0 4.3 3.1e-05 23.9 0.2 2.8 1 1 1 2 2 2 2 Receptor L domain AIPR PF10592.4 EIE85159.1 - 0.026 13.8 0.3 0.048 12.9 0.3 1.4 2 0 0 2 2 2 0 AIPR protein DGF-1_4 PF11024.3 EIE85159.1 - 0.11 12.9 0.0 0.17 12.3 0.0 1.3 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi region 4 Ribosomal_L10 PF00466.15 EIE85160.1 - 1.4e-13 50.6 0.0 2.3e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 DUF4168 PF13767.1 EIE85160.1 - 0.066 13.8 0.1 0.12 13.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4168) ACC_epsilon PF13822.1 EIE85162.1 - 0.14 12.5 0.0 0.17 12.2 0.0 1.1 1 0 0 1 1 1 0 Acyl-CoA carboxylase epsilon subunit Peptidase_C97 PF05903.9 EIE85164.1 - 1.5e-21 76.7 0.0 1.9e-21 76.4 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.8 EIE85164.1 - 0.015 15.2 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 Lecithin retinol acyltransferase IncA PF04156.9 EIE85166.1 - 0.011 15.3 27.6 0.011 15.3 19.2 4.6 1 1 3 4 4 4 0 IncA protein AAA PF00004.24 EIE85167.1 - 7.2e-44 149.1 0.0 1.5e-43 148.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EIE85167.1 - 1.9e-06 28.0 2.1 0.0015 18.7 0.0 3.4 3 1 0 3 3 2 1 AAA domain AAA_16 PF13191.1 EIE85167.1 - 4e-06 26.9 0.7 0.00037 20.5 0.1 3.0 2 1 1 3 3 3 1 AAA ATPase domain Arch_ATPase PF01637.13 EIE85167.1 - 0.00013 21.7 0.1 0.0032 17.1 0.0 2.3 1 1 1 2 2 2 1 Archaeal ATPase AAA_5 PF07728.9 EIE85167.1 - 0.0003 20.5 0.1 0.0023 17.6 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EIE85167.1 - 0.00075 19.4 0.3 0.0023 17.8 0.0 1.9 2 1 0 2 2 1 1 AAA domain (Cdc48 subfamily) ABC_tran PF00005.22 EIE85167.1 - 0.0011 19.2 0.5 0.012 15.9 0.0 2.3 2 0 0 2 2 2 1 ABC transporter AAA_14 PF13173.1 EIE85167.1 - 0.0015 18.4 0.0 0.0036 17.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 EIE85167.1 - 0.0016 17.4 0.0 0.0027 16.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) TIP49 PF06068.8 EIE85167.1 - 0.0023 16.7 0.0 0.005 15.6 0.0 1.6 1 0 0 1 1 1 1 TIP49 C-terminus AAA_29 PF13555.1 EIE85167.1 - 0.0024 17.3 0.0 0.0052 16.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 EIE85167.1 - 0.0037 18.0 1.5 0.036 14.9 0.1 2.9 3 1 0 3 3 2 1 AAA domain AAA_21 PF13304.1 EIE85167.1 - 0.0063 16.5 0.3 0.019 14.9 0.1 1.7 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 EIE85167.1 - 0.015 14.3 0.0 0.11 11.5 0.0 2.2 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus Miro PF08477.8 EIE85167.1 - 0.021 15.2 0.1 0.1 13.1 0.0 2.1 2 0 0 2 2 2 0 Miro-like protein RNA_helicase PF00910.17 EIE85167.1 - 0.027 14.6 0.0 0.053 13.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.12 EIE85167.1 - 0.027 13.8 0.5 0.41 10.0 0.0 2.6 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_25 PF13481.1 EIE85167.1 - 0.03 13.7 0.4 1.7 8.0 0.1 2.6 1 1 1 2 2 2 0 AAA domain NACHT PF05729.7 EIE85167.1 - 0.032 13.8 0.0 0.21 11.2 0.0 2.2 1 1 1 2 2 2 0 NACHT domain AAA_33 PF13671.1 EIE85167.1 - 0.046 13.5 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 EIE85167.1 - 0.047 12.8 0.1 0.096 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 EIE85167.1 - 0.057 12.8 0.0 0.21 11.0 0.0 2.0 1 0 0 1 1 1 0 FtsK/SpoIIIE family SRPRB PF09439.5 EIE85167.1 - 0.058 12.6 0.0 0.14 11.3 0.0 1.6 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Zeta_toxin PF06414.7 EIE85167.1 - 0.062 12.3 0.0 0.13 11.3 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Guanylate_kin PF00625.16 EIE85167.1 - 0.065 12.6 0.5 1.2 8.5 0.0 2.7 2 1 1 3 3 3 0 Guanylate kinase AAA_18 PF13238.1 EIE85167.1 - 0.11 12.8 2.6 0.76 10.0 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.1 EIE85167.1 - 0.23 11.7 3.1 0.35 11.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain BAG PF02179.11 EIE85169.1 - 4.7e-12 45.8 2.6 8.2e-12 45.0 1.8 1.4 1 0 0 1 1 1 1 BAG domain Mito_carr PF00153.22 EIE85170.1 - 1.2e-69 230.0 3.9 5.8e-24 83.6 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.14 EIE85170.1 - 0.00017 21.6 4.5 0.018 15.1 0.0 3.2 2 1 0 2 2 2 2 Tim17/Tim22/Tim23/Pmp24 family Coatomer_E PF04733.9 EIE85171.1 - 7.6e-83 278.0 5.3 8.7e-83 277.8 3.6 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.1 EIE85171.1 - 1.6e-07 31.5 11.1 0.018 15.3 0.0 5.4 3 2 2 5 5 5 4 Tetratricopeptide repeat Apc3 PF12895.2 EIE85171.1 - 3.6e-06 27.0 7.3 0.14 12.3 0.1 4.3 2 2 3 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EIE85171.1 - 5.6e-05 23.0 6.5 0.039 13.8 0.2 4.5 4 2 1 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.1 EIE85171.1 - 0.00052 19.5 0.9 0.0034 16.9 0.0 2.8 4 0 0 4 4 4 1 TPR repeat TPR_16 PF13432.1 EIE85171.1 - 0.0065 17.1 5.7 0.11 13.2 0.0 3.8 4 2 1 5 5 4 2 Tetratricopeptide repeat RPN7 PF10602.4 EIE85171.1 - 0.014 14.7 0.4 0.25 10.7 0.1 2.7 2 1 0 2 2 2 0 26S proteasome subunit RPN7 TPR_14 PF13428.1 EIE85171.1 - 0.079 13.6 5.7 16 6.4 0.0 4.9 5 1 1 6 6 5 0 Tetratricopeptide repeat TPR_17 PF13431.1 EIE85171.1 - 0.17 12.1 1.1 55 4.3 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 EIE85171.1 - 0.72 9.9 0.0 0.72 9.9 0.0 5.3 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_21 PF09976.4 EIE85171.1 - 0.78 9.6 4.9 0.7 9.8 0.3 2.4 1 1 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 EIE85171.1 - 7.9 6.5 6.7 22 5.1 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Isochorismatase PF00857.15 EIE85173.1 - 4.7e-17 62.4 0.2 1.4e-07 31.5 0.0 2.0 1 1 1 2 2 2 2 Isochorismatase family MatK_N PF01824.13 EIE85173.1 - 0.071 12.2 0.3 0.085 11.9 0.2 1.2 1 0 0 1 1 1 0 MatK/TrnK amino terminal region Translin PF01997.11 EIE85174.1 - 2.5e-13 50.0 0.0 3.3e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 Translin family Glyco_hydro_53 PF07745.8 EIE85174.1 - 0.0014 17.5 0.1 0.0014 17.5 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 M157 PF11624.3 EIE85174.1 - 0.088 11.9 0.1 0.11 11.6 0.0 1.0 1 0 0 1 1 1 0 MHC class I-like protein M157 CoA_transf_3 PF02515.12 EIE85175.1 - 1.2e-25 89.9 0.0 2.9e-22 78.8 0.0 2.2 1 1 1 2 2 2 2 CoA-transferase family III Nipped-B_C PF12830.2 EIE85176.1 - 4.3e-37 127.5 0.7 2.5e-36 125.1 0.1 2.4 2 1 0 2 2 2 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 EIE85176.1 - 1.7e-08 34.2 0.8 2.9e-06 27.1 0.1 3.5 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion HEAT_2 PF13646.1 EIE85176.1 - 9.5e-05 22.6 0.4 0.012 15.8 0.0 3.1 2 1 1 3 3 3 2 HEAT repeats HEAT PF02985.17 EIE85176.1 - 0.00085 19.2 0.1 0.039 14.0 0.0 3.7 4 0 0 4 4 4 1 HEAT repeat Imm43 PF15602.1 EIE85176.1 - 0.046 13.6 0.1 0.11 12.4 0.1 1.6 1 0 0 1 1 1 0 Immunity protein 43 TLD PF07534.11 EIE85178.1 - 2.2e-37 128.1 0.1 2.5e-37 127.9 0.1 1.0 1 0 0 1 1 1 1 TLD G6PD_C PF02781.11 EIE85179.1 - 2.1e-122 407.6 0.0 3.3e-122 406.9 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 EIE85179.1 - 4.6e-42 144.3 1.0 7.6e-42 143.6 0.3 1.7 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, NAD binding domain SlyX PF04102.7 EIE85180.1 - 0.0096 16.2 0.5 0.02 15.2 0.4 1.5 1 0 0 1 1 1 1 SlyX Striatin PF08232.7 EIE85180.1 - 0.029 14.6 0.4 0.048 13.9 0.3 1.3 1 0 0 1 1 1 0 Striatin family DUF3450 PF11932.3 EIE85180.1 - 0.062 12.5 1.2 0.1 11.8 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) NifU_N PF01592.11 EIE85181.1 - 5.1e-51 171.8 0.1 5.7e-51 171.7 0.1 1.0 1 0 0 1 1 1 1 NifU-like N terminal domain Cyclin_N PF00134.18 EIE85182.1 - 1.3e-11 44.1 0.2 1.7e-11 43.7 0.1 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 EIE85182.1 - 4.1e-09 37.0 0.3 5.1e-09 36.7 0.2 1.1 1 0 0 1 1 1 1 Cyclin Ank_2 PF12796.2 EIE85184.1 - 0.0003 21.0 0.0 0.00068 19.9 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EIE85184.1 - 0.0005 20.2 0.2 0.0011 19.1 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 EIE85184.1 - 0.00069 19.3 0.1 0.0014 18.3 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.1 EIE85184.1 - 0.15 12.3 0.1 0.5 10.7 0.0 1.9 1 0 0 1 1 1 0 Ankyrin repeat Ndc1_Nup PF09531.5 EIE85185.1 - 3.1e-56 191.0 6.4 4e-56 190.6 4.4 1.1 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup WD40 PF00400.27 EIE85186.1 - 0.00033 20.4 0.1 5.9 6.9 0.0 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat Spindle_Spc25 PF08234.7 EIE85187.1 - 0.0077 16.2 0.1 0.02 14.9 0.0 1.7 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 PSI_PsaF PF02507.10 EIE85187.1 - 0.35 10.3 2.8 0.28 10.7 0.7 1.6 1 1 1 2 2 2 0 Photosystem I reaction centre subunit III DUF4145 PF13643.1 EIE85187.1 - 0.47 10.3 4.1 0.14 12.0 0.8 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4145) IncA PF04156.9 EIE85187.1 - 0.76 9.3 18.7 1.9 8.0 12.9 1.6 1 1 0 1 1 1 0 IncA protein Peptidase_S46 PF10459.4 EIE85187.1 - 1.3 7.3 9.6 1.5 7.1 6.7 1.1 1 0 0 1 1 1 0 Peptidase S46 Exonuc_VII_L PF02601.10 EIE85187.1 - 2.6 7.1 13.0 3.2 6.8 9.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF342 PF03961.8 EIE85187.1 - 4.7 5.5 18.3 1.3 7.3 10.3 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF342) GrpE PF01025.14 EIE85187.1 - 5.8 6.4 23.3 0.031 13.8 7.3 2.3 1 1 1 2 2 2 0 GrpE Prismane PF03063.15 EIE85187.1 - 6 5.1 6.2 7.3 4.8 4.3 1.1 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family DOR PF14839.1 EIE85187.1 - 6.2 6.4 8.8 9.3 5.9 5.8 1.4 1 1 0 1 1 1 0 DOR family DUF3086 PF11285.3 EIE85187.1 - 8.5 5.0 13.5 2.1 7.0 5.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3086) Ribosomal_L18e PF00828.14 EIE85188.1 - 4.7e-24 85.2 0.1 4.7e-24 85.2 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 Invasin_D3 PF09134.5 EIE85188.1 - 0.068 13.0 0.0 0.089 12.6 0.0 1.2 1 0 0 1 1 1 0 Invasin, domain 3 NAP PF00956.13 EIE85189.1 - 7.7e-06 25.2 1.2 0.00072 18.7 0.6 2.0 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) DUF2217 PF10265.4 EIE85190.1 - 0.016 13.9 3.2 0.024 13.4 2.2 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Coa1 PF08695.5 EIE85191.1 - 7.7e-26 89.9 0.1 9.5e-26 89.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 AAA_2 PF07724.9 EIE85193.1 - 8e-48 162.5 0.3 4.6e-45 153.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Aldose_epim PF01263.15 EIE85193.1 - 2.1e-41 142.0 0.2 3.6e-41 141.2 0.1 1.3 1 0 0 1 1 1 1 Aldose 1-epimerase ClpB_D2-small PF10431.4 EIE85193.1 - 1.5e-24 85.6 0.1 6.7e-24 83.5 0.1 2.2 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 EIE85193.1 - 2.2e-23 82.8 0.1 6.7e-12 45.7 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EIE85193.1 - 6.9e-17 61.4 0.3 1.4e-10 41.0 0.0 3.6 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EIE85193.1 - 3.7e-14 53.1 3.2 5.1e-05 23.3 0.0 4.6 4 2 1 5 5 5 3 AAA ATPase domain Sigma54_activat PF00158.21 EIE85193.1 - 1.1e-10 41.2 0.2 1.2e-06 28.0 0.0 2.8 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_22 PF13401.1 EIE85193.1 - 2.4e-09 37.4 2.7 0.0015 18.6 0.0 4.0 3 1 0 3 3 3 2 AAA domain AAA_14 PF13173.1 EIE85193.1 - 1.3e-06 28.3 0.0 0.076 12.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 EIE85193.1 - 1.6e-06 28.0 1.0 0.15 11.6 0.1 4.1 2 1 1 3 3 3 1 Archaeal ATPase IstB_IS21 PF01695.12 EIE85193.1 - 2.4e-06 27.0 0.0 0.017 14.5 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.16 EIE85193.1 - 8.7e-06 25.0 0.2 0.45 9.6 0.0 3.3 2 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 EIE85193.1 - 2.9e-05 24.8 6.2 0.011 16.5 0.1 3.8 3 2 0 3 3 3 2 AAA domain AAA_24 PF13479.1 EIE85193.1 - 0.0002 21.0 0.0 0.012 15.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EIE85193.1 - 0.00022 21.3 0.0 0.84 9.8 0.0 3.1 3 0 0 3 3 3 2 RNA helicase RuvB_N PF05496.7 EIE85193.1 - 0.00022 20.3 2.0 0.53 9.2 0.0 3.6 3 1 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus DNA_pol3_delta2 PF13177.1 EIE85193.1 - 0.00023 20.8 0.4 0.084 12.5 0.0 3.9 3 1 0 3 3 3 1 DNA polymerase III, delta subunit AAA_19 PF13245.1 EIE85193.1 - 0.00049 19.7 0.6 0.72 9.6 0.1 3.5 3 0 0 3 3 3 1 Part of AAA domain NACHT PF05729.7 EIE85193.1 - 0.001 18.7 0.1 0.21 11.2 0.0 3.1 2 1 0 2 2 2 1 NACHT domain AAA_18 PF13238.1 EIE85193.1 - 0.0011 19.3 5.7 0.45 10.8 0.0 3.3 4 0 0 4 4 2 2 AAA domain MobB PF03205.9 EIE85193.1 - 0.0018 17.9 0.1 0.3 10.7 0.0 2.9 3 0 0 3 3 2 1 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 EIE85193.1 - 0.0026 18.0 2.3 0.22 11.8 0.0 3.5 3 1 0 3 3 3 1 ABC transporter T2SE PF00437.15 EIE85193.1 - 0.0032 16.4 0.2 0.033 13.0 0.2 2.5 2 1 0 2 2 2 1 Type II/IV secretion system protein DUF258 PF03193.11 EIE85193.1 - 0.0034 16.5 0.0 2 7.5 0.0 2.8 2 0 0 2 2 2 1 Protein of unknown function, DUF258 UPF0079 PF02367.12 EIE85193.1 - 0.0085 15.7 0.0 3.9 7.1 0.0 2.7 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 ResIII PF04851.10 EIE85193.1 - 0.0086 15.9 3.1 1.5 8.6 0.0 3.8 3 1 1 4 4 4 1 Type III restriction enzyme, res subunit PduV-EutP PF10662.4 EIE85193.1 - 0.039 13.4 0.0 4.4 6.7 0.0 3.0 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation SRP54 PF00448.17 EIE85193.1 - 0.045 13.2 0.2 3.3 7.1 0.0 2.7 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain AAA_28 PF13521.1 EIE85193.1 - 0.051 13.5 0.7 28 4.6 0.0 3.8 4 0 0 4 4 4 0 AAA domain Sigma54_activ_2 PF14532.1 EIE85193.1 - 0.068 13.2 0.0 0.57 10.2 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain ATP_bind_1 PF03029.12 EIE85193.1 - 0.071 12.6 0.1 1.7 8.1 0.0 2.6 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein LMBR1 PF04791.11 EIE85193.1 - 0.21 10.1 0.7 0.32 9.5 0.5 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein AAA_30 PF13604.1 EIE85193.1 - 2.5 7.6 6.6 3.2 7.2 0.1 3.3 3 1 0 3 3 3 0 AAA domain Prefoldin PF02996.12 EIE85193.1 - 8.9 5.9 10.9 0.75 9.4 0.2 3.9 4 1 0 4 4 4 0 Prefoldin subunit SURF4 PF02077.10 EIE85194.1 - 2.9e-92 308.8 6.8 3.3e-92 308.6 4.7 1.0 1 0 0 1 1 1 1 SURF4 family Per1 PF04080.8 EIE85194.1 - 0.25 10.7 3.2 0.28 10.5 0.3 2.0 1 1 1 2 2 2 0 Per1-like DUF1499 PF07386.6 EIE85195.1 - 0.07 13.3 0.2 0.074 13.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1499) TSGP1 PF07771.6 EIE85195.1 - 0.14 12.0 1.4 0.16 11.8 1.0 1.0 1 0 0 1 1 1 0 Tick salivary peptide group 1 OrfB_Zn_ribbon PF07282.6 EIE85196.1 - 0.03 13.9 0.1 0.23 11.1 0.0 2.5 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Mid1 PF12929.2 EIE85197.1 - 1.9e-76 257.4 16.6 7.3e-76 255.5 11.5 1.8 1 1 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.17 EIE85197.1 - 0.00092 19.5 4.0 0.073 13.4 0.9 2.9 2 1 0 2 2 2 2 Fz domain Glyco_transf_20 PF00982.16 EIE85198.1 - 4.2e-154 513.5 0.2 6.2e-154 512.9 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EIE85198.1 - 3.5e-81 271.5 0.0 8.9e-81 270.2 0.0 1.7 2 0 0 2 2 2 1 Trehalose-phosphatase Hydrolase_3 PF08282.7 EIE85198.1 - 1.4e-07 31.3 0.0 8.3e-05 22.2 0.0 2.5 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 EIE85198.1 - 0.00021 21.5 0.0 0.2 11.7 0.0 2.8 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Amidinotransf PF02274.12 EIE85198.1 - 0.0077 15.3 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 Amidinotransferase S6PP PF05116.8 EIE85198.1 - 0.024 13.9 0.0 0.056 12.7 0.0 1.6 1 0 0 1 1 1 0 Sucrose-6F-phosphate phosphohydrolase Glyco_trans_1_4 PF13692.1 EIE85198.1 - 0.043 13.9 0.0 0.098 12.8 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 CRISPR_Cse2 PF09485.5 EIE85198.1 - 0.057 13.4 0.1 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 CRISPR-associated protein Cse2 (CRISPR_cse2) DUF3216 PF11505.3 EIE85199.1 - 0.05 13.4 0.0 0.058 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) EF1G PF00647.14 EIE85200.1 - 3.1e-43 145.8 1.0 7.5e-43 144.6 0.3 1.9 2 0 0 2 2 2 1 Elongation factor 1 gamma, conserved domain GST_N PF02798.15 EIE85200.1 - 3.3e-13 49.6 0.2 2.6e-12 46.7 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EIE85200.1 - 9.7e-11 41.5 0.2 3.8e-10 39.6 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EIE85200.1 - 1.2e-09 38.2 0.0 2.7e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIE85200.1 - 7.5e-08 32.1 0.0 1.6e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EIE85200.1 - 5.4e-07 29.5 0.0 1.3e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EIE85200.1 - 5.1e-06 26.8 0.0 1.1e-05 25.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF2265 PF10023.4 EIE85200.1 - 0.037 13.1 0.0 0.064 12.3 0.0 1.3 1 0 0 1 1 1 0 Predicted aminopeptidase (DUF2265) EMP24_GP25L PF01105.19 EIE85201.1 - 1e-31 110.1 0.2 1.2e-31 109.8 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Ycf4 PF02392.11 EIE85201.1 - 0.13 11.6 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Ycf4 SAM_adeno_trans PF01887.11 EIE85201.1 - 0.13 11.3 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-l-methionine hydroxide adenosyltransferase Aminotran_5 PF00266.14 EIE85202.1 - 6.2e-23 81.1 0.0 7.9e-23 80.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V SLA_LP_auto_ag PF05889.8 EIE85202.1 - 0.016 13.6 0.0 0.027 12.9 0.0 1.3 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Pkinase PF00069.20 EIE85203.1 - 1.8e-68 230.5 0.4 1.6e-67 227.3 0.3 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE85203.1 - 4e-37 127.6 0.1 1.2e-35 122.8 0.1 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EIE85203.1 - 1.8e-05 23.8 1.8 4.1e-05 22.7 0.6 2.0 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EIE85203.1 - 9.7e-05 21.4 0.0 0.00033 19.7 0.0 1.7 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 EIE85203.1 - 0.00021 21.1 0.0 0.0013 18.5 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EIE85203.1 - 0.018 14.6 0.1 0.054 13.0 0.0 1.8 1 0 0 1 1 1 0 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.4 EIE85203.1 - 0.044 13.1 0.0 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL FLO_LFY PF01698.11 EIE85203.1 - 0.42 9.4 2.3 23 3.6 1.7 2.3 2 0 0 2 2 2 0 Floricaula / Leafy protein CLPTM1 PF05602.7 EIE85204.1 - 1.8e-133 445.5 2.3 2.3e-133 445.1 1.6 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) ABC_membrane_3 PF13748.1 EIE85204.1 - 0.038 13.0 0.0 0.074 12.0 0.0 1.4 1 0 0 1 1 1 0 ABC transporter transmembrane region DUF1240 PF06836.7 EIE85204.1 - 0.096 12.9 3.4 0.46 10.7 2.4 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1240) PQ-loop PF04193.9 EIE85204.1 - 0.11 12.0 0.1 0.11 12.0 0.0 2.7 3 0 0 3 3 3 0 PQ loop repeat 2TM PF13239.1 EIE85204.1 - 4.9 7.2 11.0 0.33 11.0 2.7 2.6 3 0 0 3 3 3 0 2TM domain COPI_assoc PF08507.5 EIE85205.1 - 6.5e-19 67.9 13.4 9.6e-17 60.9 9.3 2.0 1 1 0 1 1 1 1 COPI associated protein SdpI PF13630.1 EIE85205.1 - 0.86 9.3 16.1 0.15 11.7 3.6 2.2 1 1 1 2 2 2 0 SdpI/YhfL protein family DUF1700 PF08006.6 EIE85205.1 - 3.4 6.9 12.8 4.1 6.6 8.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) Cytochrom_B558a PF05038.8 EIE85205.1 - 3.4 7.2 7.1 1 8.9 1.5 2.0 1 1 1 2 2 2 0 Cytochrome Cytochrome b558 alpha-subunit COPI_assoc PF08507.5 EIE85206.1 - 1.2e-31 109.2 9.8 1.6e-31 108.8 6.8 1.1 1 0 0 1 1 1 1 COPI associated protein DUF1183 PF06682.7 EIE85206.1 - 0.0037 16.9 8.8 0.045 13.3 0.1 2.5 1 1 0 2 2 2 2 Protein of unknown function (DUF1183) Shisa PF13908.1 EIE85206.1 - 0.07 13.3 9.3 0.19 11.9 6.5 1.7 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator 5TM-5TMR_LYT PF07694.7 EIE85206.1 - 1.7 7.9 17.5 16 4.7 12.4 1.9 1 1 1 2 2 2 0 5TMR of 5TMR-LYT Pam17 PF08566.5 EIE85208.1 - 8.8e-32 110.1 2.1 2.8e-16 59.6 0.7 2.0 1 1 1 2 2 2 2 Mitochondrial import protein Pam17 DUF2834 PF11196.3 EIE85208.1 - 0.092 12.9 0.0 6.3 7.0 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2834) DUF3135 PF11333.3 EIE85210.1 - 0.082 13.0 0.1 0.17 12.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3135) DDE_Tnp_IS1595 PF12762.2 EIE85211.1 - 2.1e-07 30.9 0.1 3.7e-07 30.0 0.1 1.4 1 0 0 1 1 1 1 ISXO2-like transposase domain OLF PF02191.11 EIE85212.1 - 0.03 13.5 1.3 0.032 13.4 0.9 1.0 1 0 0 1 1 1 0 Olfactomedin-like domain K_oxygenase PF13434.1 EIE85212.1 - 0.41 9.5 3.2 0.45 9.3 2.2 1.1 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) DUF3958 PF13125.1 EIE85212.1 - 0.8 9.6 6.8 0.28 11.1 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3958) DUF2058 PF09831.4 EIE85212.1 - 1.2 9.0 10.0 1.4 8.7 6.9 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) rve PF00665.21 EIE85213.1 - 5.1e-23 81.4 0.0 3.5e-22 78.7 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.1 EIE85213.1 - 0.0013 18.2 0.0 0.0029 17.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.1 EIE85213.1 - 0.038 13.9 0.0 0.082 12.8 0.0 1.6 2 0 0 2 2 2 0 DDE domain Dus PF01207.12 EIE85213.1 - 0.045 12.5 0.0 0.078 11.7 0.0 1.3 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) DDE_3 PF13358.1 EIE85214.1 - 5.4e-19 68.3 0.3 3.1e-18 65.9 0.0 2.3 3 0 0 3 3 3 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE85214.1 - 1.1e-11 44.6 0.9 2.5e-11 43.4 0.7 1.7 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.1 EIE85214.1 - 0.0048 17.6 0.2 0.51 11.1 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_29 PF13551.1 EIE85214.1 - 0.0067 16.5 0.0 0.018 15.1 0.0 1.8 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EIE85214.1 - 0.018 14.7 0.1 0.098 12.3 0.0 2.4 3 0 0 3 3 3 0 Homeodomain-like domain DDE_3 PF13358.1 EIE85216.1 - 5.5e-21 74.8 0.4 7.6e-21 74.3 0.3 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease RVT_1 PF00078.22 EIE85217.1 - 2e-28 99.2 0.0 3.2e-28 98.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EIE85217.1 - 1.8e-18 66.2 0.0 3.9e-18 65.1 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EIE85217.1 - 6.7e-05 22.9 0.0 0.00024 21.1 0.0 2.0 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Mod_r PF07200.8 EIE85218.1 - 0.023 14.5 0.1 0.043 13.7 0.1 1.4 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Med9 PF07544.8 EIE85218.1 - 0.054 13.2 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Matrilin_ccoil PF10393.4 EIE85218.1 - 0.065 12.6 0.3 0.14 11.5 0.2 1.5 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin Reo_sigmaC PF04582.7 EIE85218.1 - 0.077 12.1 0.5 0.12 11.5 0.3 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF904 PF06005.7 EIE85218.1 - 0.17 12.1 2.2 0.6 10.4 1.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF904) DivIC PF04977.10 EIE85218.1 - 0.2 11.1 0.8 0.41 10.1 0.5 1.5 1 0 0 1 1 1 0 Septum formation initiator Med15 PF09606.5 EIE85219.1 - 0.028 12.6 12.5 0.04 12.1 8.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal FlgM PF04316.8 EIE85219.1 - 2.2 8.2 5.1 13 5.8 2.9 2.3 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM Transposase_21 PF02992.9 EIE85220.1 - 6.8e-22 77.6 0.0 1.5e-21 76.5 0.0 1.5 1 0 0 1 1 1 1 Transposase family tnp2 DUF1258 PF06869.7 EIE85220.1 - 0.0025 16.9 0.0 0.0041 16.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) DUF1759 PF03564.10 EIE85222.1 - 3.1e-05 23.8 0.4 4.1e-05 23.4 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) Asp_protease PF09668.5 EIE85223.1 - 3.3e-10 39.5 0.0 5.2e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 EIE85223.1 - 5.1e-08 33.3 0.0 1.5e-07 31.8 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 EIE85223.1 - 3.6e-06 26.8 0.3 1.9e-05 24.5 0.0 2.3 2 1 1 3 3 3 1 Retroviral aspartyl protease RVP_2 PF08284.6 EIE85223.1 - 5.3e-06 26.4 0.0 1.3e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EIE85223.1 - 0.00033 20.4 0.1 0.0006 19.5 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF2890 PF11081.3 EIE85223.1 - 0.93 9.5 11.0 1.9 8.4 7.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) NurA PF09376.5 EIE85224.1 - 0.035 13.5 0.4 0.041 13.3 0.3 1.2 1 0 0 1 1 1 0 NurA domain DUF4119 PF13494.1 EIE85224.1 - 0.095 12.6 2.5 0.16 11.9 0.8 2.0 1 1 1 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF4119) PRKCSH PF07915.8 EIE85224.1 - 6.6 7.6 8.9 0.57 11.0 0.8 2.4 1 1 1 2 2 2 0 Glucosidase II beta subunit-like protein Retrotrans_gag PF03732.12 EIE85225.1 - 0.0024 17.9 7.8 0.0071 16.3 0.0 2.7 2 1 0 2 2 2 1 Retrotransposon gag protein RVT_1 PF00078.22 EIE85226.1 - 2.2e-27 95.8 0.2 4.3e-27 94.8 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EIE85228.1 - 6e-28 97.3 0.0 1.2e-27 96.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 EIE85228.1 - 1.6e-05 24.2 0.0 4.1e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.5 EIE85228.1 - 0.0014 17.9 0.4 0.0033 16.7 0.3 1.6 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Transposase_21 PF02992.9 EIE85230.1 - 1.3e-22 80.0 0.1 1.3e-22 80.0 0.1 1.6 2 0 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.1 EIE85230.1 - 3.9e-05 23.0 0.3 8.6e-05 21.9 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Lzipper-MIP1 PF14389.1 EIE85231.1 - 0.005 16.9 0.4 0.013 15.5 0.3 1.7 1 0 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 ChaB PF06150.7 EIE85231.1 - 0.07 12.9 0.6 0.25 11.1 0.1 2.2 2 0 0 2 2 2 0 ChaB IncA PF04156.9 EIE85231.1 - 0.19 11.2 1.4 0.32 10.5 1.0 1.4 1 0 0 1 1 1 0 IncA protein SRR PF07709.6 EIE85231.1 - 0.24 11.7 4.4 5.5 7.6 0.0 3.5 3 0 0 3 3 3 0 Seven Residue Repeat DDE_3 PF13358.1 EIE85232.1 - 4.1e-13 49.3 0.2 5.2e-13 48.9 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE85232.1 - 0.03 14.4 0.0 0.043 13.9 0.0 1.3 1 0 0 1 1 1 0 Integrase core domain ELL PF10390.4 EIE85232.1 - 0.057 12.6 0.5 0.072 12.3 0.3 1.2 1 0 0 1 1 1 0 RNA polymerase II elongation factor ELL DUF1033 PF06279.6 EIE85232.1 - 0.077 12.8 0.5 0.17 11.6 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1033) Myb_DNA-bind_5 PF13873.1 EIE85232.1 - 0.15 11.9 0.5 8.5 6.3 0.2 2.4 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain NFRKB_winged PF14465.1 EIE85232.1 - 0.29 11.0 1.9 0.63 9.9 0.6 1.9 1 1 1 2 2 2 0 NFRKB Winged Helix-like Transposase_21 PF02992.9 EIE85233.1 - 1.3e-06 27.7 0.0 2.2e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 DDE_3 PF13358.1 EIE85234.1 - 2e-13 50.3 0.0 3.1e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EIE85235.1 - 3.8e-18 65.6 0.1 5.5e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE85235.1 - 3e-08 33.5 0.5 1.1e-07 31.8 0.4 1.8 2 0 0 2 2 2 1 Transposase FAM70 PF14967.1 EIE85235.1 - 0.022 13.9 0.0 0.032 13.4 0.0 1.2 1 0 0 1 1 1 0 FAM70 protein OLF PF02191.11 EIE85236.1 - 0.03 13.5 1.3 0.032 13.4 0.9 1.0 1 0 0 1 1 1 0 Olfactomedin-like domain K_oxygenase PF13434.1 EIE85236.1 - 0.41 9.5 3.2 0.45 9.3 2.2 1.1 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) DUF3958 PF13125.1 EIE85236.1 - 0.8 9.6 6.8 0.28 11.1 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3958) DUF2058 PF09831.4 EIE85236.1 - 1.2 9.0 10.0 1.4 8.7 6.9 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) DDE_3 PF13358.1 EIE85237.1 - 1.3e-17 63.8 0.0 3.4e-17 62.5 0.0 1.7 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE85237.1 - 4e-09 36.4 0.7 1.7e-08 34.3 0.7 2.0 2 1 0 2 2 2 1 Transposase HTH_Tnp_Tc3_2 PF01498.13 EIE85238.1 - 1.2e-05 25.2 4.5 1.4e-05 25.0 1.6 2.0 1 1 2 3 3 3 1 Transposase HTH_23 PF13384.1 EIE85238.1 - 0.1 12.2 0.0 0.27 10.9 0.0 1.7 2 0 0 2 2 2 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.13 EIE85239.1 - 1.2e-05 25.2 4.5 1.4e-05 25.0 1.6 2.0 1 1 2 3 3 3 1 Transposase HTH_23 PF13384.1 EIE85239.1 - 0.1 12.2 0.0 0.27 10.9 0.0 1.7 2 0 0 2 2 2 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.13 EIE85240.1 - 3.5e-08 33.3 0.3 3.5e-08 33.3 0.2 2.1 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 EIE85240.1 - 0.00034 20.7 1.9 0.00073 19.6 1.3 1.6 1 1 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_ISL3 PF13542.1 EIE85240.1 - 0.0069 15.5 2.0 0.023 13.8 0.5 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_32 PF13565.1 EIE85240.1 - 0.055 14.2 2.8 0.066 14.0 0.9 2.0 2 0 0 2 2 2 0 Homeodomain-like domain HTH_12 PF08461.5 EIE85240.1 - 0.06 13.0 0.1 0.19 11.4 0.1 1.8 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain DUF4330 PF14221.1 EIE85240.1 - 0.11 12.3 0.1 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4330) HTH_23 PF13384.1 EIE85240.1 - 0.12 12.0 2.9 1.7 8.3 0.2 2.5 2 0 0 2 2 2 0 Homeodomain-like domain HTH_21 PF13276.1 EIE85240.1 - 0.19 11.7 3.2 0.61 10.1 0.1 2.3 2 0 0 2 2 2 0 HTH-like domain RVT_1 PF00078.22 EIE85241.1 - 1.6e-28 99.5 0.0 2.5e-28 98.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EIE85241.1 - 1e-15 57.3 0.0 2.6e-15 56.0 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EIE85241.1 - 0.0013 18.6 1.0 0.0044 17.0 0.0 2.2 2 1 1 3 3 3 1 Endonuclease/Exonuclease/phosphatase family TSC22 PF01166.13 EIE85244.1 - 0.00016 21.5 1.7 0.00026 20.9 1.2 1.3 1 0 0 1 1 1 1 TSC-22/dip/bun family DUF972 PF06156.8 EIE85244.1 - 0.002 18.4 0.5 0.0034 17.7 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF972) DivIC PF04977.10 EIE85244.1 - 0.016 14.6 3.5 0.03 13.8 2.4 1.4 1 0 0 1 1 1 0 Septum formation initiator Lebercilin PF15619.1 EIE85244.1 - 0.043 13.2 4.8 0.063 12.6 3.3 1.2 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease ATG16 PF08614.6 EIE85244.1 - 0.056 13.2 3.4 0.094 12.5 2.3 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF904 PF06005.7 EIE85244.1 - 0.09 13.0 3.9 0.16 12.3 2.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DDE_3 PF13358.1 EIE85245.1 - 4.2e-16 58.9 0.0 8.3e-16 58.0 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE85245.1 - 5.3e-06 26.4 0.8 1.8e-05 24.6 0.8 1.8 2 0 0 2 2 2 1 Transposase NUDIX_4 PF14815.1 EIE85245.1 - 0.0078 15.6 0.3 0.013 14.9 0.2 1.4 1 0 0 1 1 1 1 NUDIX domain DUF1759 PF03564.10 EIE85246.1 - 0.00021 21.1 0.4 0.00021 21.1 0.3 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1759) Asp_protease PF09668.5 EIE85247.1 - 3.8e-10 39.3 0.0 6.2e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 EIE85247.1 - 4.9e-08 33.3 0.0 1.4e-07 31.9 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 EIE85247.1 - 6e-06 26.1 0.2 3e-05 23.8 0.0 2.3 2 1 0 2 2 2 1 Retroviral aspartyl protease RVP_2 PF08284.6 EIE85247.1 - 6.8e-06 26.0 0.0 1.6e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EIE85247.1 - 0.00033 20.4 0.1 0.00062 19.5 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease NOA36 PF06524.7 EIE85247.1 - 3.2 6.9 7.4 6.4 5.9 5.1 1.4 1 0 0 1 1 1 0 NOA36 protein HTH_Tnp_Tc3_2 PF01498.13 EIE85248.1 - 0.00025 21.0 1.2 0.00059 19.8 0.5 1.9 1 1 1 2 2 2 1 Transposase HTH_Tnp_Tc3_2 PF01498.13 EIE85249.1 - 6.3e-06 26.1 2.3 0.00011 22.2 0.6 2.3 2 0 0 2 2 2 1 Transposase HTH_7 PF02796.10 EIE85249.1 - 0.00023 20.9 0.2 0.013 15.3 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_IclR PF09339.5 EIE85249.1 - 0.00025 20.5 0.0 0.00051 19.5 0.0 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_23 PF13384.1 EIE85249.1 - 0.00027 20.4 0.0 0.00066 19.2 0.0 1.6 2 0 0 2 2 2 1 Homeodomain-like domain HTH_11 PF08279.7 EIE85249.1 - 0.00031 20.3 0.0 0.00056 19.4 0.0 1.4 1 0 0 1 1 1 1 HTH domain HTH_38 PF13936.1 EIE85249.1 - 0.0039 16.7 0.0 0.0087 15.5 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.7 EIE85249.1 - 0.0045 16.4 0.1 0.028 13.8 0.0 2.0 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_17 PF12728.2 EIE85249.1 - 0.0063 16.7 0.0 0.011 15.9 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.1 EIE85249.1 - 0.01 15.9 0.0 0.019 15.1 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn helix HTH_Crp_2 PF13545.1 EIE85249.1 - 0.012 15.4 0.1 0.028 14.2 0.0 1.6 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain Sigma70_r4 PF04545.11 EIE85249.1 - 0.015 14.6 0.0 0.031 13.5 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_24 PF13412.1 EIE85249.1 - 0.018 14.4 0.0 0.038 13.3 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding GerE PF00196.14 EIE85249.1 - 0.021 14.1 0.0 0.042 13.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family UPF0122 PF04297.9 EIE85249.1 - 0.026 14.5 0.0 0.045 13.7 0.0 1.3 1 0 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like MarR_2 PF12802.2 EIE85249.1 - 0.033 13.8 0.0 0.063 12.9 0.0 1.4 1 0 0 1 1 1 0 MarR family Terminase_5 PF06056.7 EIE85249.1 - 0.033 13.7 0.0 0.057 12.9 0.0 1.3 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) HTH_AsnC-type PF13404.1 EIE85249.1 - 0.034 13.7 0.0 0.063 12.8 0.0 1.4 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_22 PF13309.1 EIE85249.1 - 0.059 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 HTH domain HTH_6 PF01418.12 EIE85249.1 - 0.077 12.7 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family HTH_31 PF13560.1 EIE85249.1 - 0.08 13.1 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_4 PF13613.1 EIE85249.1 - 0.083 12.4 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_36 PF13730.1 EIE85249.1 - 0.094 12.8 0.2 0.28 11.3 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain DUF603 PF04645.7 EIE85249.1 - 0.11 12.4 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF603 TetR_N PF00440.18 EIE85249.1 - 0.12 12.0 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family rve PF00665.21 EIE85255.1 - 1.2e-17 64.0 0.0 8.4e-17 61.3 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 EIE85255.1 - 9.3e-17 61.0 0.1 2.2e-16 59.8 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE85255.1 - 6.2e-09 35.4 0.1 1.6e-08 34.0 0.1 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.1 EIE85255.1 - 1.5e-07 31.7 0.1 4e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 EIE85255.1 - 1.8e-06 27.7 0.1 8.5e-06 25.6 0.1 2.2 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EIE85255.1 - 0.00078 19.2 0.0 0.0018 18.0 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.12 EIE85255.1 - 0.0043 17.0 4.1 0.0051 16.8 0.0 3.3 5 0 0 5 5 5 1 Retrotransposon gag protein Asp_protease PF09668.5 EIE85255.1 - 0.011 15.2 0.2 0.093 12.3 0.1 2.4 2 0 0 2 2 2 0 Aspartyl protease Tudor-knot PF11717.3 EIE85255.1 - 0.056 13.1 2.9 0.086 12.5 0.1 2.7 2 0 0 2 2 2 0 RNA binding activity-knot of a chromodomain IncA PF04156.9 EIE85255.1 - 1.5 8.3 6.7 3.9 7.0 4.6 1.7 1 0 0 1 1 1 0 IncA protein DDE_3 PF13358.1 EIE85257.1 - 2.3e-19 69.5 0.1 4.4e-19 68.6 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE85257.1 - 1e-09 38.3 1.1 4e-09 36.4 0.8 2.1 1 0 0 1 1 1 1 Transposase HTH_Tnp_4 PF13613.1 EIE85257.1 - 0.00076 18.9 0.0 0.0014 18.0 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease HTH_23 PF13384.1 EIE85257.1 - 0.0042 16.6 0.0 0.013 15.1 0.0 1.8 1 0 0 1 1 1 1 Homeodomain-like domain FAM70 PF14967.1 EIE85257.1 - 0.04 13.1 0.0 0.06 12.5 0.0 1.2 1 0 0 1 1 1 0 FAM70 protein Bac_small_YrzI PF09501.5 EIE85259.1 - 0.049 13.5 0.1 0.12 12.3 0.1 1.7 1 0 0 1 1 1 0 Probable sporulation protein (Bac_small_yrzI) GTP_EFTU PF00009.22 EIE85260.1 - 2.6e-28 98.7 0.4 1.9e-24 86.1 0.1 2.7 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain EFG_C PF00679.19 EIE85260.1 - 2e-21 75.6 0.0 5.6e-21 74.2 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EIE85260.1 - 8.2e-07 29.0 0.1 1.7e-06 28.0 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 SRPRB PF09439.5 EIE85260.1 - 0.014 14.5 0.0 0.039 13.1 0.0 1.7 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit Ras PF00071.17 EIE85260.1 - 0.046 13.1 0.0 1.1 8.6 0.0 2.2 1 1 0 2 2 2 0 Ras family UAA PF08449.6 EIE85261.1 - 1.6e-55 188.2 7.2 2.7e-55 187.4 5.0 1.3 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.10 EIE85261.1 - 6.9e-05 22.0 1.8 0.0001 21.4 1.3 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter 7TMR-DISM_7TM PF07695.6 EIE85261.1 - 0.00035 20.2 15.4 0.015 14.9 4.0 2.4 2 0 0 2 2 2 2 7TM diverse intracellular signalling EmrE PF13536.1 EIE85261.1 - 0.0007 19.7 5.2 0.0007 19.7 3.6 2.2 2 1 0 2 2 2 1 Multidrug resistance efflux transporter EamA PF00892.15 EIE85261.1 - 0.001 19.0 7.1 0.001 19.0 4.9 2.1 2 0 0 2 2 2 1 EamA-like transporter family DUF3671 PF12420.3 EIE85261.1 - 0.039 13.9 0.7 0.039 13.9 0.5 2.9 1 1 2 3 3 3 0 Protein of unknown function DUF1129 PF06570.6 EIE85261.1 - 0.6 9.3 7.2 0.056 12.7 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) RRM_1 PF00076.17 EIE85262.1 - 2e-19 68.9 0.4 4.1e-19 67.9 0.3 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE85262.1 - 1.4e-14 53.8 0.1 2.2e-14 53.1 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE85262.1 - 0.003 17.3 0.1 0.0051 16.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SURF1 PF02104.10 EIE85263.1 - 5.4e-64 215.9 0.0 6.6e-64 215.6 0.0 1.1 1 0 0 1 1 1 1 SURF1 family Vezatin PF12632.2 EIE85264.1 - 1.7e-18 66.6 4.4 2.4e-18 66.1 3.1 1.3 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes CRAL_TRIO PF00650.15 EIE85265.1 - 6.7e-24 84.1 0.1 1.1e-23 83.5 0.0 1.4 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 EIE85265.1 - 0.00018 21.4 0.0 0.00028 20.8 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Glycos_transf_2 PF00535.21 EIE85266.1 - 0.00016 21.3 0.0 0.0005 19.7 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 2 Pik1 PF11522.3 EIE85266.1 - 0.0012 18.4 0.1 0.0024 17.5 0.1 1.4 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 Sod_Fe_N PF00081.17 EIE85267.1 - 0.051 13.8 0.3 0.055 13.7 0.2 1.4 1 0 0 1 1 1 0 Iron/manganese superoxide dismutases, alpha-hairpin domain DUF2607 PF10795.4 EIE85267.1 - 0.052 13.3 0.4 0.053 13.3 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2607) Grp1_Fun34_YaaH PF01184.14 EIE85268.1 - 5e-69 231.8 16.7 5.8e-69 231.5 11.6 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF3483 PF11982.3 EIE85268.1 - 5.6 6.1 6.5 1.1 8.4 0.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3483) Zip PF02535.17 EIE85269.1 - 1.6e-52 178.4 11.7 1.6e-52 178.4 8.1 2.1 2 0 0 2 2 2 2 ZIP Zinc transporter Oxidored_q5_N PF01059.12 EIE85269.1 - 0.79 9.6 6.2 0.11 12.3 0.7 2.2 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase chain 4, amino terminus SelP_N PF04592.9 EIE85269.1 - 4.4 6.6 18.5 2.8 7.2 9.1 2.1 2 0 0 2 2 2 0 Selenoprotein P, N terminal region SMC_hinge PF06470.8 EIE85270.1 - 2.5e-27 95.2 0.2 2.5e-27 95.2 0.1 2.5 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain SMC_N PF02463.14 EIE85270.1 - 6.1e-15 55.0 54.6 3.4e-14 52.5 37.8 2.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EIE85270.1 - 3.2e-06 27.3 0.5 3.2e-06 27.3 0.4 3.3 3 1 0 3 3 3 1 AAA domain AAA_13 PF13166.1 EIE85270.1 - 1e-05 24.2 32.5 1e-05 24.2 22.5 4.8 3 2 2 5 5 5 2 AAA domain Reo_sigmaC PF04582.7 EIE85270.1 - 2.8e-05 23.4 19.4 0.024 13.7 1.5 4.9 3 2 2 5 5 5 2 Reovirus sigma C capsid protein AAA_29 PF13555.1 EIE85270.1 - 7.1e-05 22.2 0.0 0.00016 21.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Atg14 PF10186.4 EIE85270.1 - 0.0039 16.1 9.6 0.0039 16.1 6.6 6.2 2 2 4 6 6 6 1 UV radiation resistance protein and autophagy-related subunit 14 ABC_tran PF00005.22 EIE85270.1 - 0.052 13.8 0.0 0.052 13.8 0.0 6.1 3 2 0 3 3 3 0 ABC transporter AAA_16 PF13191.1 EIE85270.1 - 2 8.3 0.0 2 8.3 0.0 4.2 4 2 1 5 5 5 0 AAA ATPase domain Ribosomal_L18ae PF01775.12 EIE85272.1 - 3.2e-46 156.2 3.7 4e-46 155.9 2.5 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain UPRTase PF14681.1 EIE85274.1 - 4.4e-55 186.1 0.0 6.5e-55 185.5 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase ArsC PF03960.10 EIE85274.1 - 7.6e-13 48.5 0.9 2.1e-12 47.0 0.6 1.7 1 1 0 1 1 1 1 ArsC family Pribosyltran PF00156.22 EIE85274.1 - 0.00019 21.1 0.0 0.00059 19.5 0.0 1.9 1 1 0 1 1 1 1 Phosphoribosyl transferase domain DUF1687 PF07955.6 EIE85274.1 - 0.0047 16.9 0.1 0.0089 16.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) Glutaredoxin PF00462.19 EIE85274.1 - 0.065 13.2 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 Glutaredoxin Gly_transf_sug PF04488.10 EIE85275.1 - 8.5e-08 32.5 0.7 3.1e-07 30.7 0.3 1.9 1 1 1 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 EIE85275.1 - 5.4e-05 22.4 0.2 6.8e-05 22.1 0.1 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.2 EIE85275.1 - 0.0086 14.6 0.5 0.017 13.6 0.1 1.5 1 1 1 2 2 2 1 TcdA/TcdB catalytic glycosyltransferase domain Thioesterase PF00975.15 EIE85276.1 - 0.028 14.6 0.6 0.034 14.3 0.4 1.1 1 0 0 1 1 1 0 Thioesterase domain Rho_GDI PF02115.12 EIE85276.1 - 0.061 12.7 1.2 0.072 12.5 0.8 1.1 1 0 0 1 1 1 0 RHO protein GDP dissociation inhibitor HGTP_anticodon2 PF12745.2 EIE85276.1 - 0.067 12.3 6.1 0.081 12.0 4.2 1.0 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs RCC1 PF00415.13 EIE85277.1 - 1.1e-14 54.3 8.5 0.00014 22.0 0.1 5.3 6 0 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EIE85277.1 - 1.4e-12 46.8 15.9 1.6e-06 27.5 0.1 5.6 6 1 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.2 EIE85277.1 - 5.1e-08 32.5 0.1 1.2e-07 31.3 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIE85277.1 - 6.1e-05 22.5 0.3 0.00012 21.6 0.2 1.5 1 0 0 1 1 1 1 F-box domain UBA PF00627.26 EIE85280.1 - 2.3e-11 43.1 0.2 7e-11 41.6 0.1 1.9 1 0 0 1 1 1 1 UBA/TS-N domain ubiquitin PF00240.18 EIE85280.1 - 3.6e-08 32.6 0.0 4.3e-07 29.2 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin family CUE PF02845.11 EIE85280.1 - 0.00041 19.7 0.4 0.0098 15.3 0.1 2.5 2 0 0 2 2 2 1 CUE domain DUF2407 PF10302.4 EIE85280.1 - 0.00068 19.7 0.2 0.0024 18.0 0.0 2.0 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 EIE85280.1 - 0.0068 16.2 0.1 0.051 13.4 0.1 2.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD PF11976.3 EIE85280.1 - 0.011 15.4 0.1 0.028 14.1 0.0 1.7 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like INCENP_ARK-bind PF03941.10 EIE85280.1 - 1.7 8.5 7.4 4.2 7.2 0.1 3.8 2 1 1 3 3 3 0 Inner centromere protein, ARK binding region Neur_chan_memb PF02932.11 EIE85280.1 - 6.7 6.5 6.4 12 5.7 3.8 1.9 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Pyrophosphatase PF00719.14 EIE85281.1 - 6.5e-48 162.1 0.2 8.8e-48 161.6 0.2 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase DHH PF01368.15 EIE85281.1 - 0.35 10.4 1.7 0.8 9.3 0.7 1.9 1 1 0 1 1 1 0 DHH family SH3_9 PF14604.1 EIE85284.1 - 1.1e-12 47.3 0.1 1.9e-12 46.5 0.0 1.5 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 EIE85284.1 - 1.8e-11 43.2 0.0 2.5e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EIE85284.1 - 7.7e-09 34.9 0.0 1.1e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 EIE85284.1 - 0.01 16.0 0.0 0.014 15.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial SH3 domain Peptidase_S9 PF00326.16 EIE85285.1 - 2.5e-50 170.6 0.1 3.5e-50 170.1 0.1 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EIE85285.1 - 2.4e-06 27.3 0.0 3.3e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIE85285.1 - 4.9e-05 23.0 0.0 0.00013 21.6 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EIE85285.1 - 6.8e-05 22.8 0.0 0.00012 22.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EIE85285.1 - 6.8e-05 22.4 0.0 8.6e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Peptidase_S15 PF02129.13 EIE85285.1 - 7.1e-05 22.3 0.9 0.0019 17.6 0.4 2.5 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.13 EIE85285.1 - 0.004 16.4 0.1 0.019 14.2 0.1 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 EIE85285.1 - 0.048 13.0 0.4 2.9 7.2 0.1 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 EIE85285.1 - 0.056 13.0 0.1 1.2 8.6 0.1 2.1 1 1 0 1 1 1 0 alpha/beta hydrolase fold AXE1 PF05448.7 EIE85285.1 - 0.076 11.5 0.0 0.13 10.7 0.0 1.7 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) DUF3141 PF11339.3 EIE85285.1 - 0.12 10.7 0.0 0.16 10.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3141) DPPIV_N PF00930.16 EIE85286.1 - 6.4e-22 77.6 0.4 1.3e-21 76.6 0.3 1.5 1 1 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region PAS_9 PF13426.1 EIE85287.1 - 2.3e-31 108.2 0.0 6.2e-16 58.6 0.0 3.6 4 0 0 4 4 4 3 PAS domain PAS_3 PF08447.6 EIE85287.1 - 1.8e-19 69.6 0.0 1.9e-14 53.4 0.0 3.5 3 0 0 3 3 3 2 PAS fold PAS PF00989.19 EIE85287.1 - 2.6e-19 69.0 0.0 6.1e-08 32.4 0.0 3.9 4 0 0 4 4 4 3 PAS fold PAS_11 PF14598.1 EIE85287.1 - 1.1e-14 54.3 0.0 7.7e-09 35.4 0.0 3.0 2 1 0 2 2 2 2 PAS domain PAS_4 PF08448.5 EIE85287.1 - 7.4e-11 42.0 0.0 6.5e-05 22.9 0.0 3.5 3 0 0 3 3 3 3 PAS fold PAS_8 PF13188.1 EIE85287.1 - 2.8e-06 26.9 0.0 0.068 13.0 0.0 3.5 3 0 0 3 3 3 2 PAS domain PAS_2 PF08446.6 EIE85287.1 - 0.0036 17.7 0.0 2.7 8.4 0.0 3.1 3 0 0 3 3 3 1 PAS fold DUF4428 PF14471.1 EIE85287.1 - 0.051 13.3 0.3 0.54 10.0 0.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4428) DUF3039 PF11238.3 EIE85288.1 - 0.16 11.4 0.6 0.42 10.0 0.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3039) Rft-1 PF04506.8 EIE85289.1 - 3.5e-64 217.1 31.6 2.2e-32 112.1 8.0 3.4 1 1 2 3 3 3 3 Rft protein Polysacc_synt_C PF14667.1 EIE85289.1 - 1.3e-05 25.0 11.2 1.3e-05 25.0 7.7 2.5 2 1 0 2 2 2 1 Polysaccharide biosynthesis C-terminal domain Polysacc_synt PF01943.12 EIE85289.1 - 0.00013 21.3 25.1 0.023 13.9 3.8 2.9 1 1 2 3 3 3 2 Polysaccharide biosynthesis protein DUF3098 PF11297.3 EIE85289.1 - 0.038 13.7 2.5 0.12 12.0 1.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3098) HTH_Tnp_Tc3_2 PF01498.13 EIE85290.1 - 0.071 13.1 0.0 0.092 12.8 0.0 1.2 1 0 0 1 1 1 0 Transposase DUF155 PF02582.9 EIE85292.1 - 6.3e-34 117.3 0.1 7.6e-34 117.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 E1_dh PF00676.15 EIE85293.1 - 3.8e-102 341.0 0.0 4.5e-102 340.7 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 EIE85293.1 - 0.0045 15.9 0.0 0.0096 14.8 0.0 1.6 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase KRTAP7 PF15034.1 EIE85293.1 - 0.042 14.5 5.2 0.086 13.4 0.2 2.9 2 1 0 2 2 2 0 KRTAP type 7 family Cullin_binding PF03556.10 EIE85294.1 - 1.1e-16 61.0 2.3 1.1e-16 61.0 1.6 2.3 1 1 1 2 2 2 1 Cullin binding FA_hydroxylase PF04116.8 EIE85295.1 - 7.3e-16 58.5 14.9 7.3e-16 58.5 10.3 2.1 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF2627 PF11118.3 EIE85295.1 - 0.13 12.3 1.2 1.3 9.1 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2627) F-box-like PF12937.2 EIE85296.1 - 9e-09 34.9 0.2 3.4e-08 33.0 0.1 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EIE85296.1 - 4.6e-05 22.9 0.4 0.0002 20.9 0.0 2.2 2 0 0 2 2 2 1 F-box domain F-box-like_2 PF13013.1 EIE85296.1 - 0.054 13.2 2.8 0.31 10.7 0.9 2.6 2 1 0 2 2 2 0 F-box-like domain PUF PF00806.14 EIE85297.1 - 7.1e-52 170.0 16.4 3.4e-07 29.3 0.2 7.5 7 0 0 7 7 7 7 Pumilio-family RNA binding repeat CTD_bind PF04818.8 EIE85297.1 - 0.24 11.6 2.1 28 5.0 0.1 3.7 3 1 1 4 4 4 0 RNA polymerase II-binding domain. HECT PF00632.20 EIE85298.1 - 1.1e-75 254.7 0.0 2e-75 253.8 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) ATP-synt_C PF00137.16 EIE85299.1 - 7.5e-29 99.4 25.0 3e-16 59.0 5.3 2.4 3 0 0 3 3 3 2 ATP synthase subunit C G0-G1_switch_2 PF15103.1 EIE85299.1 - 0.19 11.9 0.9 0.87 9.8 0.3 2.1 2 0 0 2 2 2 0 G0/G1 switch protein 2 Oxidored_q2 PF00420.19 EIE85299.1 - 3.7 7.2 8.5 0.68 9.5 1.5 2.8 1 1 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L CopD PF05425.8 EIE85299.1 - 8.7 6.6 11.7 0.087 13.0 1.6 2.2 2 1 0 2 2 2 0 Copper resistance protein D SusD-like_2 PF12771.2 EIE85300.1 - 0.045 12.1 0.0 0.056 11.8 0.0 1.1 1 0 0 1 1 1 0 Starch-binding associating with outer membrane DUF2416 PF10315.4 EIE85301.1 - 5.5e-16 58.7 0.4 6.2e-16 58.5 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2416) Med18 PF09637.5 EIE85302.1 - 1.7e-05 24.5 0.0 4.1e-05 23.2 0.0 1.5 1 1 0 1 1 1 1 Med18 protein Ribosomal_L35Ae PF01247.13 EIE85304.1 - 3.9e-42 141.9 1.5 4.3e-42 141.7 1.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 EIE85304.1 - 0.0029 17.4 0.1 0.34 10.8 0.0 2.1 2 0 0 2 2 2 2 RimM N-terminal domain Lipase_GDSL_2 PF13472.1 EIE85305.1 - 0.035 14.2 0.1 0.053 13.6 0.0 1.3 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Whi5 PF08528.6 EIE85307.1 - 0.00084 18.8 0.0 0.0014 18.1 0.0 1.4 1 0 0 1 1 1 1 Whi5 like Bromo_MP PF01573.11 EIE85307.1 - 0.02 13.8 0.1 0.025 13.5 0.0 1.2 1 0 0 1 1 1 0 Bromovirus movement protein NTF2 PF02136.15 EIE85308.1 - 9.8e-35 119.4 0.0 1.1e-34 119.3 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.4 EIE85308.1 - 0.0033 17.1 0.0 0.0037 17.0 0.0 1.1 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 GATA PF00320.22 EIE85309.1 - 4.2e-17 61.1 4.3 7.5e-17 60.3 3.0 1.4 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.7 EIE85309.1 - 1.6e-05 24.1 0.3 2.8e-05 23.3 0.2 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding DZR PF12773.2 EIE85309.1 - 0.00027 20.6 2.7 0.096 12.5 0.8 2.0 1 1 1 2 2 2 2 Double zinc ribbon zf-ribbon_3 PF13248.1 EIE85309.1 - 0.0021 17.1 3.9 0.009 15.1 0.5 2.2 2 0 0 2 2 2 1 zinc-ribbon domain zinc_ribbon_2 PF13240.1 EIE85309.1 - 0.0023 17.3 0.7 0.0023 17.3 0.5 2.0 2 0 0 2 2 2 1 zinc-ribbon domain NMD3 PF04981.8 EIE85309.1 - 0.013 14.6 0.1 0.013 14.5 0.1 1.1 1 0 0 1 1 1 0 NMD3 family OrfB_Zn_ribbon PF07282.6 EIE85309.1 - 0.028 14.0 2.8 0.041 13.5 1.9 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Rpr2 PF04032.11 EIE85309.1 - 0.13 12.1 1.6 3.8 7.4 0.2 2.3 2 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Auto_anti-p27 PF06677.7 EIE85309.1 - 0.13 12.0 0.6 0.31 10.8 0.4 1.6 1 1 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) GFA PF04828.9 EIE85309.1 - 0.23 11.4 4.1 0.91 9.5 2.8 1.9 1 1 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme Nudix_N_2 PF14803.1 EIE85309.1 - 0.29 10.8 2.6 3.1 7.5 1.9 2.3 1 1 1 2 2 2 0 Nudix N-terminal Prim_Zn_Ribbon PF08273.7 EIE85309.1 - 0.3 11.1 2.9 0.88 9.6 1.7 1.9 1 1 1 2 2 2 0 Zinc-binding domain of primase-helicase DNA_RNApol_7kD PF03604.8 EIE85309.1 - 1 8.8 4.3 0.64 9.5 1.2 1.9 2 1 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zf-RanBP PF00641.13 EIE85309.1 - 3.2 6.9 7.9 17 4.6 3.2 2.4 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others DUF2130 PF09903.4 EIE85310.1 - 0.064 12.0 1.3 0.97 8.1 0.4 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2130) Arm PF00514.18 EIE85311.1 - 1.1e-87 285.2 11.2 3.8e-12 45.5 0.0 9.3 10 0 0 10 10 10 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EIE85311.1 - 4.1e-22 78.2 0.0 4.2e-08 33.3 0.0 5.8 1 1 4 6 6 6 6 HEAT repeats IBB PF01749.15 EIE85311.1 - 6.2e-22 77.5 4.5 1.1e-21 76.7 3.1 1.4 1 0 0 1 1 1 1 Importin beta binding domain HEAT_EZ PF13513.1 EIE85311.1 - 2.2e-18 66.1 1.4 1.4e-07 31.7 0.0 5.9 5 1 1 6 6 6 2 HEAT-like repeat HEAT PF02985.17 EIE85311.1 - 2.2e-17 61.5 0.0 0.00037 20.3 0.0 6.9 7 0 0 7 7 7 3 HEAT repeat Adaptin_N PF01602.15 EIE85311.1 - 1.3e-07 30.3 0.0 0.00054 18.4 0.0 2.2 1 1 1 2 2 2 2 Adaptin N terminal region Arm_2 PF04826.8 EIE85311.1 - 2.2e-07 30.2 0.0 0.039 13.0 0.0 4.3 2 1 2 4 4 4 2 Armadillo-like V-ATPase_H_C PF11698.3 EIE85311.1 - 0.0003 20.6 0.0 0.81 9.6 0.0 4.0 3 2 2 5 5 5 1 V-ATPase subunit H RICTOR_V PF14668.1 EIE85311.1 - 0.00033 20.5 3.8 0.75 9.7 0.0 4.6 4 1 1 5 5 5 2 Rapamycin-insensitive companion of mTOR, domain 5 Proteasom_PSMB PF10508.4 EIE85311.1 - 0.0031 15.8 0.0 0.053 11.7 0.0 2.6 2 1 0 2 2 2 1 Proteasome non-ATPase 26S subunit HEAT_PBS PF03130.11 EIE85311.1 - 0.036 14.5 0.5 6 7.6 0.0 3.9 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat TraE PF05309.6 EIE85312.1 - 0.002 17.2 0.1 0.0038 16.4 0.1 1.4 1 0 0 1 1 1 1 TraE protein CoA_binding PF02629.14 EIE85313.1 - 1.5e-29 102.3 1.2 1.5e-29 102.3 0.8 2.4 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 EIE85313.1 - 3.1e-23 82.0 0.2 6.5e-23 81.0 0.1 1.5 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 EIE85313.1 - 5e-07 29.4 0.0 1e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 EIE85313.1 - 0.00068 19.7 0.5 0.0019 18.3 0.1 2.0 2 1 1 3 3 3 1 CoA binding domain GFO_IDH_MocA PF01408.17 EIE85313.1 - 0.017 15.6 0.1 0.041 14.3 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Ribosomal_L28e PF01778.12 EIE85314.1 - 1.7e-34 118.6 4.6 2.2e-34 118.3 3.2 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family PGAP1 PF07819.8 EIE85315.1 - 3.5e-78 262.2 0.1 4.9e-78 261.8 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EIE85315.1 - 0.00083 19.1 0.0 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIE85315.1 - 0.002 18.0 0.0 0.003 17.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 EIE85315.1 - 0.0024 17.1 0.1 0.0046 16.2 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.15 EIE85315.1 - 0.0077 15.8 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold LCAT PF02450.10 EIE85315.1 - 0.017 14.1 0.0 0.031 13.2 0.0 1.4 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Lipase_3 PF01764.20 EIE85315.1 - 0.02 14.5 0.0 0.036 13.6 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF915 PF06028.6 EIE85315.1 - 0.058 12.4 0.2 0.67 9.0 0.1 2.4 2 1 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) B12D PF06522.6 EIE85316.1 - 2.9e-16 58.9 0.0 3.4e-16 58.6 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit BAR PF03114.13 EIE85317.1 - 1.9e-12 47.2 3.8 5.8e-12 45.6 2.3 2.0 1 1 0 1 1 1 1 BAR domain SH3_9 PF14604.1 EIE85317.1 - 4.5e-06 26.1 0.1 9.5e-06 25.1 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EIE85317.1 - 5.6e-06 25.7 0.1 1.1e-05 24.7 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain RhoGEF PF00621.15 EIE85317.1 - 8.7e-06 25.7 18.6 5.2e-05 23.1 11.2 3.4 2 1 0 2 2 2 1 RhoGEF domain SH3_1 PF00018.23 EIE85317.1 - 9.9e-05 21.6 0.5 0.00036 19.8 0.4 2.1 1 0 0 1 1 1 1 SH3 domain eIF-5a PF01287.15 EIE85318.1 - 1.5e-28 98.5 0.3 2.1e-28 98.0 0.2 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 EIE85318.1 - 9.8e-05 21.9 0.6 0.00017 21.1 0.4 1.4 1 0 0 1 1 1 1 KOW motif EFP_N PF08207.7 EIE85318.1 - 0.028 14.2 0.0 0.053 13.4 0.0 1.5 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain VP_N-CPKC PF11475.3 EIE85318.1 - 0.095 12.2 0.0 1.5 8.3 0.0 2.3 2 0 0 2 2 2 0 Virion protein N terminal domain CtaG_Cox11 PF04442.9 EIE85319.1 - 2.2e-57 193.1 0.0 2.5e-57 192.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 PH PF00169.24 EIE85320.1 - 2.7e-13 50.0 1.3 2.7e-13 50.0 0.9 2.2 2 1 0 2 2 2 1 PH domain PH_8 PF15409.1 EIE85320.1 - 2.1e-07 30.9 2.9 7.5e-05 22.7 0.1 2.5 2 0 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.1 EIE85320.1 - 4.4e-06 26.8 0.4 8.6e-06 25.9 0.3 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 EIE85320.1 - 0.0001 22.5 3.2 0.00057 20.1 2.2 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain RhoGAP PF00620.22 EIE85321.1 - 2.5e-39 134.3 0.7 4.2e-39 133.5 0.5 1.3 1 0 0 1 1 1 1 RhoGAP domain DUF4518 PF15008.1 EIE85321.1 - 0.025 13.6 0.3 0.036 13.0 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) zf-CCHC PF00098.18 EIE85322.1 - 4.2e-06 26.4 16.5 0.0019 18.0 2.4 2.3 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.1 EIE85322.1 - 0.0043 16.7 15.3 0.025 14.3 2.0 2.5 1 1 1 2 2 2 2 Zinc knuckle FAM176 PF14851.1 EIE85322.1 - 0.052 13.2 3.6 0.091 12.4 2.5 1.4 1 0 0 1 1 1 0 FAM176 family HNH PF01844.18 EIE85322.1 - 1.1 9.1 12.3 0.12 12.2 0.5 2.8 3 0 0 3 3 3 0 HNH endonuclease zf-CCHC_4 PF14392.1 EIE85322.1 - 2.3 7.9 12.8 1.4 8.6 1.2 2.4 2 0 0 2 2 2 0 Zinc knuckle TAFII55_N PF04658.8 EIE85323.1 - 0.024 14.1 0.3 0.03 13.8 0.2 1.2 1 0 0 1 1 1 0 TAFII55 protein conserved region DUF569 PF04601.8 EIE85324.1 - 0.096 12.1 0.2 0.64 9.4 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF569) HTH_Tnp_ISL3 PF13542.1 EIE85325.1 - 0.012 14.7 0.2 0.015 14.4 0.1 1.1 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_23 PF13384.1 EIE85325.1 - 0.056 13.1 0.0 0.064 12.9 0.0 1.2 1 0 0 1 1 1 0 Homeodomain-like domain DDE_3 PF13358.1 EIE85326.1 - 3.1e-13 49.6 0.2 4.1e-13 49.3 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE85326.1 - 0.029 14.4 0.0 0.042 13.9 0.0 1.3 1 0 0 1 1 1 0 Integrase core domain DUF1033 PF06279.6 EIE85326.1 - 0.049 13.4 0.8 0.077 12.8 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1033) Myb_DNA-bind_5 PF13873.1 EIE85326.1 - 0.13 12.1 0.5 11 6.0 0.2 2.5 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Transposase_21 PF02992.9 EIE85329.1 - 3.9e-23 81.7 0.1 6.2e-23 81.0 0.1 1.3 1 0 0 1 1 1 1 Transposase family tnp2 3HCDH_N PF02737.13 EIE85330.1 - 0.035 13.7 0.0 0.057 13.0 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SHR3_chaperone PF08229.6 EIE85330.1 - 0.042 12.7 0.1 0.08 11.8 0.1 1.4 1 0 0 1 1 1 0 ER membrane protein SH3 DUF4218 PF13960.1 EIE85330.1 - 0.057 12.8 0.1 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) FlgM PF04316.8 EIE85331.1 - 0.72 9.8 4.5 4.3 7.3 2.8 2.2 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM RRF_GI PF12614.3 EIE85332.1 - 0.002 17.9 0.8 0.0023 17.7 0.6 1.2 1 0 0 1 1 1 1 Ribosome recycling factor FKBP_N PF01346.13 EIE85333.1 - 0.0016 18.4 1.0 0.0034 17.4 0.7 1.5 1 0 0 1 1 1 1 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase LAG1-DNAbind PF09271.6 EIE85333.1 - 0.028 14.9 0.3 0.061 13.8 0.2 1.5 1 0 0 1 1 1 0 LAG1, DNA binding HTH_37 PF13744.1 EIE85333.1 - 1.1 9.1 6.6 20 5.0 3.7 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain DDE_3 PF13358.1 EIE85334.1 - 4.1e-17 62.2 0.6 1.3e-16 60.6 0.0 2.1 3 0 0 3 3 3 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE85334.1 - 1.7e-11 44.0 0.5 3.7e-11 42.9 0.4 1.6 1 0 0 1 1 1 1 Transposase DUF4218 PF13960.1 EIE85335.1 - 0.035 13.5 0.0 0.066 12.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) LysR_substrate PF03466.15 EIE85335.1 - 0.1 11.7 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 LysR substrate binding domain DDE_Tnp_IS1595 PF12762.2 EIE85336.1 - 2.9e-06 27.2 0.1 5.3e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 ISXO2-like transposase domain Transposase_21 PF02992.9 EIE85337.1 - 6.9e-22 77.6 0.0 1e-21 77.0 0.0 1.2 1 0 0 1 1 1 1 Transposase family tnp2 DUF1258 PF06869.7 EIE85337.1 - 0.002 17.2 0.0 0.0031 16.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) LysR_substrate PF03466.15 EIE85337.1 - 0.15 11.1 0.0 0.27 10.2 0.0 1.3 1 0 0 1 1 1 0 LysR substrate binding domain DUF1203 PF06718.6 EIE85338.1 - 0.085 12.6 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1203) Transposase_21 PF02992.9 EIE85339.1 - 1.2e-12 47.4 0.0 2.1e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DDE_3 PF13358.1 EIE85340.1 - 4.3e-21 75.2 0.4 5.9e-21 74.7 0.3 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF569 PF04601.8 EIE85341.1 - 0.096 12.1 0.2 0.64 9.4 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF569) Helicase_C_3 PF13625.1 EIE85342.1 - 0.085 12.6 0.1 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Helicase conserved C-terminal domain Chromo PF00385.19 EIE85343.1 - 3.2e-12 45.9 0.1 5.7e-12 45.1 0.1 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.21 EIE85343.1 - 0.052 13.6 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain DEAD PF00270.24 EIE85344.1 - 1.2e-43 148.5 0.0 5.1e-43 146.4 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIE85344.1 - 2.1e-26 91.6 0.1 4e-26 90.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIE85344.1 - 0.0001 22.2 0.0 0.0003 20.6 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 EIE85344.1 - 0.018 13.4 0.0 0.12 10.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) Aa_trans PF01490.13 EIE85345.1 - 1.9e-61 207.8 30.6 2.1e-61 207.6 21.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.1 EIE85345.1 - 7.7e-15 54.3 38.8 1e-14 53.9 26.9 1.0 1 0 0 1 1 1 1 Amino acid permease Spore_permease PF03845.8 EIE85345.1 - 0.00037 19.2 20.0 0.00037 19.2 13.9 2.0 1 1 1 2 2 2 1 Spore germination protein JmjC PF02373.17 EIE85346.1 - 3.1e-42 143.4 1.5 3.1e-42 143.4 1.0 2.5 2 0 0 2 2 2 1 JmjC domain, hydroxylase PLU-1 PF08429.6 EIE85346.1 - 2.6e-26 92.3 8.4 4.6e-26 91.5 5.8 1.4 1 0 0 1 1 1 1 PLU-1-like protein ARID PF01388.16 EIE85346.1 - 7.2e-23 80.2 0.1 1.8e-22 78.9 0.0 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain PHD PF00628.24 EIE85346.1 - 5e-20 70.9 22.9 2.7e-12 46.1 4.3 3.5 3 0 0 3 3 3 2 PHD-finger JmjN PF02375.12 EIE85346.1 - 3.9e-17 61.4 3.4 4.2e-17 61.3 1.1 2.1 2 0 0 2 2 2 1 jmjN domain zf-C5HC2 PF02928.11 EIE85346.1 - 6.1e-12 45.4 14.3 6.1e-12 45.4 9.9 2.5 2 0 0 2 2 2 1 C5HC2 zinc finger Prok-RING_1 PF14446.1 EIE85346.1 - 0.014 15.1 2.5 0.014 15.1 1.8 2.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-PHD-like PF15446.1 EIE85346.1 - 0.015 14.5 9.9 0.029 13.6 1.4 2.6 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain zf-HC5HC2H PF13771.1 EIE85346.1 - 0.016 15.3 18.5 0.05 13.7 0.4 3.9 3 0 0 3 3 3 0 PHD-like zinc-binding domain P-II PF00543.17 EIE85346.1 - 0.079 13.4 0.0 0.6 10.6 0.0 2.4 3 0 0 3 3 3 0 Nitrogen regulatory protein P-II PSP1 PF04468.7 EIE85347.1 - 1.9e-34 117.4 3.7 1.9e-34 117.4 2.6 1.9 2 0 0 2 2 2 1 PSP1 C-terminal conserved region GATA PF00320.22 EIE85348.1 - 4.2e-08 32.3 6.4 8.1e-08 31.4 4.4 1.5 1 0 0 1 1 1 1 GATA zinc finger DUF1133 PF06576.6 EIE85348.1 - 0.019 14.1 0.2 0.029 13.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1133) DDE_Tnp_4 PF13359.1 EIE85348.1 - 0.036 13.6 0.3 0.053 13.1 0.2 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease SAG PF04092.8 EIE85348.1 - 0.083 13.2 5.3 0.17 12.2 3.7 1.5 1 0 0 1 1 1 0 SRS domain UPF0051 PF01458.12 EIE85348.1 - 0.22 10.9 4.6 0.31 10.4 3.2 1.3 1 0 0 1 1 1 0 Uncharacterized protein family (UPF0051) DZR PF12773.2 EIE85348.1 - 6.2 6.7 7.7 54 3.7 5.4 2.4 1 1 0 1 1 1 0 Double zinc ribbon Ank_2 PF12796.2 EIE85349.1 - 6.4e-14 52.0 0.5 2.4e-06 27.7 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EIE85349.1 - 2.3e-12 46.0 0.2 2.3e-05 23.9 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EIE85349.1 - 7e-12 45.5 1.0 1.6e-06 28.4 0.0 2.8 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIE85349.1 - 1.1e-09 37.5 1.8 0.0076 16.4 0.0 4.2 4 1 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 EIE85349.1 - 1e-06 28.7 0.1 0.026 14.7 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) KilA-N PF04383.8 EIE85349.1 - 0.00024 20.7 0.0 0.00075 19.0 0.0 1.8 1 0 0 1 1 1 1 KilA-N domain F-112 PF09645.5 EIE85349.1 - 0.072 12.9 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 F-112 protein Mif2_N PF15624.1 EIE85349.1 - 1.1 9.8 6.5 2.6 8.6 4.5 1.6 1 0 0 1 1 1 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Acyltransferase PF01553.16 EIE85351.1 - 1.5e-09 37.4 0.0 7.6e-09 35.1 0.0 2.0 1 1 0 1 1 1 1 Acyltransferase Sec61_beta PF03911.11 EIE85352.1 - 1.7e-18 66.0 0.3 1.9e-18 65.9 0.2 1.0 1 0 0 1 1 1 1 Sec61beta family Glycogen_syn PF05693.8 EIE85353.1 - 0 1084.3 0.0 0 1084.1 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glyco_transf_5 PF08323.6 EIE85353.1 - 6.1e-09 35.7 0.0 1.3e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.15 EIE85353.1 - 2e-08 33.8 0.0 5.4e-05 22.6 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EIE85353.1 - 0.00028 21.0 0.1 0.00085 19.4 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain PQ-loop PF04193.9 EIE85354.1 - 2.8e-20 71.6 12.6 1.2e-14 53.5 0.6 3.0 3 0 0 3 3 3 2 PQ loop repeat DHFR_2 PF06442.6 EIE85354.1 - 0.052 13.1 0.0 0.23 11.1 0.0 1.9 2 0 0 2 2 2 0 R67 dihydrofolate reductase Ricin_B_lectin PF00652.17 EIE85355.1 - 1.7e-18 66.8 3.0 3.4e-14 52.9 0.3 1.8 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 EIE85355.1 - 1.2e-14 54.5 0.3 4.9e-07 30.0 0.1 2.4 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Rad51 PF08423.6 EIE85356.1 - 3e-136 452.3 0.2 3.7e-136 452.0 0.1 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EIE85356.1 - 1.4e-13 50.6 0.1 2e-13 50.2 0.1 1.2 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.1 EIE85356.1 - 4.4e-11 42.7 2.5 1.3e-10 41.2 0.8 2.4 1 1 1 2 2 2 1 Helix-hairpin-helix domain RecA PF00154.16 EIE85356.1 - 3.6e-10 39.4 0.1 5.8e-10 38.7 0.1 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 EIE85356.1 - 6.7e-06 25.3 0.2 1.3e-05 24.4 0.1 1.6 1 1 0 1 1 1 1 KaiC PAXNEB PF05625.6 EIE85356.1 - 0.0053 15.6 0.0 0.015 14.1 0.0 1.6 2 0 0 2 2 2 1 PAXNEB protein AAA_22 PF13401.1 EIE85356.1 - 0.017 15.2 0.0 0.04 14.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.20 EIE85356.1 - 0.03 13.8 0.2 0.074 12.5 0.1 1.7 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain HHH PF00633.18 EIE85356.1 - 0.051 13.2 0.2 0.12 12.0 0.2 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif DnaB_C PF03796.10 EIE85356.1 - 0.11 11.3 0.0 0.36 9.6 0.0 1.8 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain Nucleoplasmin PF03066.10 EIE85357.1 - 0.057 12.9 2.5 0.06 12.8 1.7 1.1 1 0 0 1 1 1 0 Nucleoplasmin RXT2_N PF08595.6 EIE85357.1 - 0.059 13.1 2.1 0.067 12.9 1.5 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal PBP1_TM PF14812.1 EIE85357.1 - 0.12 12.7 2.4 0.13 12.5 1.7 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pkinase PF00069.20 EIE85358.1 - 8.2e-19 67.7 0.8 1.6e-18 66.8 0.6 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE85358.1 - 8.1e-12 44.7 0.6 1.4e-11 44.0 0.4 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DDE_3 PF13358.1 EIE85359.1 - 0.00014 21.5 0.0 0.00018 21.2 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease RVT_1 PF00078.22 EIE85360.1 - 4.3e-36 124.2 0.1 8.1e-36 123.3 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.1 EIE85360.1 - 0.002 18.4 0.2 0.0062 16.8 0.1 1.9 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase zf-CCHC PF00098.18 EIE85361.1 - 0.018 14.9 18.7 0.023 14.5 0.9 3.1 3 0 0 3 3 3 0 Zinc knuckle DnaJ_CXXCXGXG PF00684.14 EIE85361.1 - 0.4 10.7 7.5 5.4 7.1 0.1 2.6 2 0 0 2 2 2 0 DnaJ central domain Pro_isomerase PF00160.16 EIE85362.1 - 9.9e-46 155.7 0.2 1.1e-45 155.6 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SHD1 PF03983.7 EIE85363.1 - 1.7e-28 98.0 0.0 3.7e-28 96.9 0.0 1.6 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_9 PF14604.1 EIE85363.1 - 1.3e-14 53.4 0.2 5.2e-08 32.3 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 EIE85363.1 - 1.7e-13 49.7 0.2 2.4e-08 33.2 0.1 2.6 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 EIE85363.1 - 4.9e-13 48.3 0.0 1.5e-05 24.4 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SMC_N PF02463.14 EIE85364.1 - 1.1e-29 103.2 6.3 3.1e-29 101.7 4.3 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EIE85364.1 - 2.2e-13 51.0 19.6 2.2e-13 51.0 13.6 5.5 2 2 2 4 4 1 1 AAA domain AAA_15 PF13175.1 EIE85364.1 - 5.3e-07 29.0 0.0 5.3e-07 29.0 0.0 4.2 2 2 2 4 4 2 1 AAA ATPase domain AAA_29 PF13555.1 EIE85364.1 - 1.9e-05 24.0 0.0 3.9e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.1 EIE85364.1 - 0.00026 21.0 33.8 0.00036 20.5 1.0 4.4 2 2 1 3 3 3 2 AAA domain SbcCD_C PF13558.1 EIE85364.1 - 0.0013 18.5 0.0 0.0044 16.9 0.0 1.9 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit ABC_tran PF00005.22 EIE85364.1 - 0.15 12.3 0.0 0.15 12.3 0.0 5.6 3 2 0 3 3 2 0 ABC transporter EzrA PF06160.7 EIE85364.1 - 0.58 8.2 74.6 0.18 9.9 3.3 4.7 2 2 1 3 3 3 0 Septation ring formation regulator, EzrA AAA_13 PF13166.1 EIE85364.1 - 1.7 6.9 91.7 0.45 8.9 0.1 5.2 3 2 2 5 5 5 0 AAA domain Reo_sigmaC PF04582.7 EIE85364.1 - 2.4 7.2 8.1 0.41 9.7 0.6 3.1 3 1 0 4 4 4 0 Reovirus sigma C capsid protein AAA_16 PF13191.1 EIE85364.1 - 2.9 7.8 8.0 0.83 9.6 0.0 3.5 3 0 0 3 3 3 0 AAA ATPase domain PA_decarbox PF05870.6 EIE85365.1 - 0.14 11.6 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 Phenolic acid decarboxylase (PAD) GPI-anchored PF10342.4 EIE85366.1 - 3.7e-14 52.9 0.3 3.7e-14 52.9 0.2 2.5 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Med3 PF11593.3 EIE85366.1 - 0.51 9.5 20.3 0.81 8.8 14.1 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF605 PF04652.11 EIE85366.1 - 4.6 6.5 17.0 6.2 6.1 11.8 1.1 1 0 0 1 1 1 0 Vta1 like RhoGEF PF00621.15 EIE85367.1 - 8.9e-18 64.7 0.8 2.4e-17 63.3 0.0 2.1 2 1 0 2 2 2 1 RhoGEF domain BAR PF03114.13 EIE85367.1 - 1.5e-16 60.6 1.5 2.3e-16 60.0 0.1 2.0 2 1 1 3 3 3 1 BAR domain SH3_9 PF14604.1 EIE85367.1 - 7.4e-11 41.4 0.6 1.3e-10 40.6 0.4 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EIE85367.1 - 9.6e-11 40.9 0.5 1.8e-10 40.0 0.3 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EIE85367.1 - 7.6e-07 28.5 0.0 1.8e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain ALIX_LYPXL_bnd PF13949.1 EIE85367.1 - 0.04 12.8 3.9 0.015 14.2 1.0 1.6 2 0 0 2 2 2 0 ALIX V-shaped domain binding to HIV MutS_III PF05192.13 EIE85367.1 - 0.099 12.4 0.0 0.83 9.4 0.0 2.2 1 1 0 1 1 1 0 MutS domain III PEHE PF15275.1 EIE85367.1 - 0.1 13.0 0.1 0.31 11.5 0.1 1.8 1 0 0 1 1 1 0 PEHE domain MFS_1 PF07690.11 EIE85368.1 - 7.2e-30 103.8 52.7 2.4e-19 69.2 18.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EIE85368.1 - 5.2e-07 28.4 7.6 5.2e-07 28.4 5.2 2.7 1 1 2 3 3 3 3 MFS/sugar transport protein SporV_AA PF12164.3 EIE85370.1 - 0.015 15.2 0.1 0.039 13.9 0.1 1.7 1 0 0 1 1 1 0 Stage V sporulation protein AA DUF87 PF01935.12 EIE85370.1 - 3.9 7.2 8.8 1.9 8.2 2.4 2.1 1 1 1 2 2 2 0 Domain of unknown function DUF87 Aminotran_1_2 PF00155.16 EIE85371.1 - 1.4e-24 86.7 0.0 1.6e-24 86.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 EIE85371.1 - 0.00011 20.9 0.0 0.00014 20.5 0.0 1.5 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase GCR1_C PF12550.3 EIE85372.1 - 5.1e-26 90.3 0.7 5.1e-25 87.1 0.2 2.6 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes zf-DHHC PF01529.15 EIE85373.1 - 8.6e-20 70.8 8.2 8.6e-20 70.8 5.7 3.8 2 1 2 4 4 4 2 DHHC palmitoyltransferase VIT1 PF01988.14 EIE85373.1 - 0.026 13.9 0.0 0.039 13.4 0.0 1.3 1 0 0 1 1 1 0 VIT family DivIC PF04977.10 EIE85373.1 - 0.88 9.1 6.9 25 4.4 0.0 2.6 2 0 0 2 2 2 0 Septum formation initiator NUDIX_4 PF14815.1 EIE85374.1 - 6e-20 70.7 0.4 2.1e-19 68.9 0.0 2.0 2 0 0 2 2 2 1 NUDIX domain HhH-GPD PF00730.20 EIE85374.1 - 4.6e-19 68.6 0.0 1.3e-18 67.2 0.0 1.7 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EIE85374.1 - 0.00029 20.3 0.0 0.00074 19.0 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.4 EIE85374.1 - 0.0029 17.7 4.1 0.0029 17.7 2.9 2.0 2 0 0 2 2 2 1 Iron-sulfur binding domain of endonuclease III Gemini_mov PF01708.11 EIE85375.1 - 0.034 13.6 0.2 0.034 13.6 0.1 2.0 2 0 0 2 2 2 0 Geminivirus putative movement protein DUSP PF06337.7 EIE85376.1 - 0.013 15.8 1.4 0.66 10.4 1.0 2.1 1 1 0 1 1 1 0 DUSP domain DUF3020 PF11223.3 EIE85377.1 - 1.1e-20 73.7 10.5 1.1e-20 73.7 7.3 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3020) Septin PF00735.13 EIE85378.1 - 5.8e-58 196.1 8.8 2.8e-55 187.3 6.1 2.9 1 1 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EIE85378.1 - 3.8e-08 33.3 0.0 9.2e-08 32.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EIE85378.1 - 6.6e-06 25.6 0.0 0.00031 20.2 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EIE85378.1 - 8.7e-05 21.7 0.0 0.013 14.6 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 MobB PF03205.9 EIE85378.1 - 0.00015 21.4 0.0 0.0011 18.6 0.0 2.2 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 EIE85378.1 - 0.00021 20.8 0.0 0.00085 18.8 0.0 1.9 2 0 0 2 2 2 1 FtsK/SpoIIIE family Miro PF08477.8 EIE85378.1 - 0.0005 20.5 0.6 0.0025 18.3 0.4 2.3 1 1 0 1 1 1 1 Miro-like protein AAA_24 PF13479.1 EIE85378.1 - 0.0018 17.8 0.0 0.0046 16.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EIE85378.1 - 0.0019 18.4 1.0 0.79 10.0 0.0 2.7 2 1 0 2 2 2 1 AAA domain ATP_bind_1 PF03029.12 EIE85378.1 - 0.0044 16.5 0.0 0.69 9.4 0.0 2.4 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein ABC_tran PF00005.22 EIE85378.1 - 0.0094 16.2 0.1 0.019 15.2 0.0 1.8 1 1 0 1 1 1 1 ABC transporter AAA_22 PF13401.1 EIE85378.1 - 0.012 15.7 0.3 0.038 14.1 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EIE85378.1 - 0.023 14.5 0.0 0.05 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF463 PF04317.7 EIE85378.1 - 0.029 12.9 0.0 0.083 11.4 0.0 1.8 2 0 0 2 2 2 0 YcjX-like family, DUF463 DUF3987 PF13148.1 EIE85378.1 - 0.033 12.7 0.0 0.085 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Na_trans_assoc PF06512.8 EIE85378.1 - 0.037 13.9 2.6 2.7 7.9 0.1 2.2 2 0 0 2 2 2 0 Sodium ion transport-associated Ras PF00071.17 EIE85378.1 - 0.039 13.3 0.1 5.8 6.2 0.1 2.4 1 1 1 2 2 2 0 Ras family RNA_helicase PF00910.17 EIE85378.1 - 0.047 13.8 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.1 EIE85378.1 - 0.049 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.4 EIE85378.1 - 0.065 12.7 0.1 1.9 7.9 0.0 2.6 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 EIE85378.1 - 0.13 11.7 0.1 0.26 10.7 0.1 1.8 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.18 EIE85378.1 - 0.21 11.4 10.1 0.49 10.2 0.3 3.3 2 1 1 3 3 3 0 Dynamin family Cytomega_TRL10 PF06084.6 EIE85378.1 - 0.23 11.2 1.5 31 4.3 1.6 2.3 2 0 0 2 2 2 0 Cytomegalovirus TRL10 protein AAA_17 PF13207.1 EIE85378.1 - 1 10.2 4.2 1.2 9.9 0.1 2.6 1 1 0 2 2 2 0 AAA domain CENP-B_dimeris PF09026.5 EIE85378.1 - 9.1 6.5 13.1 0.91 9.7 5.5 1.9 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF1175 PF06672.6 EIE85379.1 - 0.096 12.0 0.0 0.1 11.9 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1175) GTP_EFTU PF00009.22 EIE85380.1 - 6.6e-57 191.9 0.0 1.2e-56 191.1 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EIE85380.1 - 9.7e-37 125.1 0.0 2.4e-36 123.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EIE85380.1 - 5e-16 58.5 1.1 5e-16 58.5 0.7 2.4 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EIE85380.1 - 0.00097 19.0 0.3 0.0029 17.5 0.2 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 EIE85380.1 - 0.0013 18.3 0.4 0.0013 18.3 0.3 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 4 Semialdhyde_dhC PF02774.13 EIE85380.1 - 0.12 12.2 0.3 0.32 10.8 0.0 1.8 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain PPI_Ypi1 PF07491.6 EIE85381.1 - 4.5e-20 71.0 9.4 4.5e-20 71.0 6.5 2.5 1 1 1 2 2 2 1 Protein phosphatase inhibitor SR-25 PF10500.4 EIE85381.1 - 0.0077 15.7 7.9 0.0085 15.5 5.5 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein CDC45 PF02724.9 EIE85381.1 - 0.37 8.7 6.8 0.47 8.4 4.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Zip PF02535.17 EIE85381.1 - 2.5 7.0 5.9 3 6.7 4.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Ribosomal_S27 PF01599.14 EIE85382.1 - 5.2e-29 99.8 2.8 1.1e-28 98.8 2.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S27a ubiquitin PF00240.18 EIE85382.1 - 2.8e-19 68.2 0.0 6.3e-19 67.1 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.3 EIE85382.1 - 2.6e-10 39.8 0.0 5.1e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like IBR PF01485.16 EIE85382.1 - 0.012 15.5 0.8 0.019 14.8 0.5 1.4 1 0 0 1 1 1 0 IBR domain Ubiquitin_2 PF14560.1 EIE85382.1 - 0.013 15.7 0.0 0.054 13.7 0.0 2.0 2 1 0 2 2 2 0 Ubiquitin-like domain GATase_5 PF13507.1 EIE85383.1 - 1.1e-100 335.8 0.1 1.9e-100 335.0 0.1 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 EIE85383.1 - 2.4e-48 164.0 0.6 1.7e-26 93.0 0.0 2.4 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 EIE85383.1 - 1.2e-23 83.1 0.2 6.2e-23 80.8 0.0 2.4 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain TRP_2 PF08344.6 EIE85383.1 - 0.25 11.2 1.4 2.3 8.1 0.1 2.7 3 0 0 3 3 3 0 Transient receptor ion channel II Ribonuclease_3 PF00636.21 EIE85384.1 - 4.8e-50 168.7 0.2 1.1e-23 83.7 0.0 2.3 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EIE85384.1 - 1e-36 125.7 0.4 4.7e-17 62.1 0.0 3.9 2 2 0 2 2 2 2 Ribonuclease-III-like A_deaminase PF00962.17 EIE85385.1 - 1.7e-29 102.7 0.2 2.2e-29 102.4 0.1 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase ABC1 PF03109.11 EIE85387.1 - 7.2e-32 109.8 0.2 1.5e-31 108.8 0.1 1.5 1 0 0 1 1 1 1 ABC1 family DDE_3 PF13358.1 EIE85388.1 - 4.6e-12 45.8 0.0 5e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Sulphotransf PF09037.5 EIE85389.1 - 0.069 12.6 0.1 0.091 12.2 0.1 1.1 1 0 0 1 1 1 0 Stf0 sulphotransferase Rad52_Rad22 PF04098.10 EIE85391.1 - 0.015 15.0 0.1 0.027 14.2 0.0 1.5 1 1 0 1 1 1 0 Rad52/22 family double-strand break repair protein DUF643 PF04867.7 EIE85391.1 - 0.049 14.0 2.8 0.14 12.5 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF643) DDE_3 PF13358.1 EIE85392.1 - 1.8e-19 69.9 0.1 1.1e-18 67.4 0.0 1.9 1 1 0 1 1 1 1 DDE superfamily endonuclease Xan_ur_permease PF00860.15 EIE85393.1 - 8.5e-26 90.3 35.7 4.8e-25 87.8 22.8 2.6 2 1 0 2 2 2 1 Permease family DUF2834 PF11196.3 EIE85393.1 - 0.023 14.8 3.4 0.12 12.5 2.2 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2834) G-patch PF01585.18 EIE85395.1 - 2.3e-14 52.9 3.0 3.8e-14 52.1 2.1 1.4 1 0 0 1 1 1 1 G-patch domain FHA PF00498.21 EIE85395.1 - 4.9e-13 48.9 0.1 1.2e-12 47.7 0.0 1.7 1 0 0 1 1 1 1 FHA domain G-patch_2 PF12656.2 EIE85395.1 - 4.3e-08 32.9 1.7 5e-08 32.6 0.0 1.9 2 0 0 2 2 2 1 DExH-box splicing factor binding site Zn_clus PF00172.13 EIE85396.1 - 3.6e-08 33.1 8.2 7.4e-08 32.1 5.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EIE85396.1 - 3.8e-08 32.5 3.5 6.8e-08 31.6 2.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain muHD PF10291.4 EIE85398.1 - 1e-19 70.7 0.2 2.4e-19 69.5 0.1 1.7 1 1 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.18 EIE85398.1 - 4.6e-05 23.5 2.2 0.0001 22.3 0.1 2.6 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Pectinesterase PF01095.14 EIE85399.1 - 9.3e-44 149.1 7.3 1.7e-43 148.3 5.0 1.4 1 1 0 1 1 1 1 Pectinesterase Pectinesterase PF01095.14 EIE85401.1 - 1.9e-46 157.9 4.0 4.1e-46 156.9 2.8 1.4 1 1 0 1 1 1 1 Pectinesterase Glyco_hydro_18 PF00704.23 EIE85402.1 - 1.4e-20 74.0 0.9 1.1e-19 71.1 0.6 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_19 PF03427.8 EIE85402.1 - 3.7e-08 33.0 2.9 3.7e-08 33.0 2.0 2.4 3 0 0 3 3 3 1 Carbohydrate binding domain (family 19) Lustrin_cystein PF14625.1 EIE85402.1 - 6.8 6.8 8.4 9.4 6.4 0.8 2.8 1 1 1 2 2 2 0 Lustrin, cysteine-rich repeated domain DUF21 PF01595.15 EIE85403.1 - 1.8e-17 63.1 0.3 8.5e-11 41.4 0.1 2.5 2 0 0 2 2 2 2 Domain of unknown function DUF21 CBS PF00571.23 EIE85403.1 - 3.2e-12 46.0 0.0 8.8e-05 22.2 0.0 2.4 2 0 0 2 2 2 2 CBS domain Mur_ligase_M PF08245.7 EIE85404.1 - 2.2e-10 40.8 0.0 1.1e-09 38.6 0.0 2.0 1 1 0 1 1 1 1 Mur ligase middle domain FliM PF02154.10 EIE85404.1 - 0.069 12.8 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Flagellar motor switch protein FliM DNA_primase_S PF01896.14 EIE85405.1 - 4.3e-50 169.3 1.2 7.1e-50 168.5 0.9 1.4 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit DUF647 PF04884.9 EIE85406.1 - 6.8e-28 97.5 0.0 8.3e-28 97.2 0.0 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis DUF647 PF04884.9 EIE85407.1 - 9.4e-16 57.7 0.1 1.4e-15 57.1 0.1 1.2 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis Sigma70_r1_2 PF00140.15 EIE85408.1 - 0.024 14.3 0.2 0.063 12.9 0.0 1.7 2 0 0 2 2 2 0 Sigma-70 factor, region 1.2 Chs3p PF12271.3 EIE85411.1 - 1.2e-110 369.0 21.2 1.9e-110 368.5 14.7 1.3 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit Nucleotid_trans PF03407.11 EIE85411.1 - 1.7e-24 86.7 0.1 2.5e-24 86.2 0.0 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase DUF3357 PF11837.3 EIE85411.1 - 0.11 12.4 0.1 0.35 10.7 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) p450 PF00067.17 EIE85412.1 - 1.8e-85 287.2 0.0 2.2e-85 286.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RhoGAP PF00620.22 EIE85413.1 - 3.3e-38 130.7 1.1 3.3e-38 130.7 0.7 2.1 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.18 EIE85413.1 - 5.2e-05 23.3 0.0 5.2e-05 23.3 0.0 3.3 4 0 0 4 4 4 1 Fes/CIP4, and EFC/F-BAR homology domain HisKA_3 PF07730.8 EIE85413.1 - 0.14 12.4 2.1 0.59 10.5 0.2 2.8 1 1 1 2 2 2 0 Histidine kinase UBA_e1_C PF09358.5 EIE85413.1 - 6.9 6.8 10.2 4.1 7.5 0.5 3.5 2 1 1 3 3 3 0 Ubiquitin-activating enzyme e1 C-terminal domain Myb_DNA-bind_6 PF13921.1 EIE85414.1 - 5.6e-81 266.5 32.9 6.1e-15 55.0 0.7 10.0 5 4 5 10 10 10 8 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EIE85414.1 - 3.5e-65 215.8 40.5 2.3e-10 40.3 0.0 10.4 10 0 0 10 10 10 9 Myb-like DNA-binding domain Myb_DNA-bind_2 PF08914.6 EIE85414.1 - 6.9e-07 28.9 5.8 0.1 12.4 0.0 6.0 6 0 0 6 6 6 2 Rap1 Myb domain Myb_DNA-bind_4 PF13837.1 EIE85414.1 - 1.1e-06 28.6 37.9 0.0044 17.1 0.2 8.4 8 2 1 9 9 9 5 Myb/SANT-like DNA-binding domain Rap1_C PF11626.3 EIE85414.1 - 0.0032 17.3 14.6 3.3 7.6 0.0 5.5 3 1 2 5 5 5 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain 6PF2K PF01591.13 EIE85415.1 - 2.8e-72 242.4 0.0 4.3e-72 241.7 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EIE85415.1 - 3.5e-10 40.2 0.3 9.1e-10 38.8 0.0 1.8 3 0 0 3 3 3 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EIE85415.1 - 2.8e-07 30.5 0.0 5.2e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EIE85415.1 - 0.0032 18.2 0.0 0.0085 16.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain tRNA_lig_kinase PF08303.6 EIE85415.1 - 0.019 14.8 0.0 0.04 13.7 0.0 1.5 1 0 0 1 1 1 0 tRNA ligase kinase domain Val_tRNA-synt_C PF10458.4 EIE85415.1 - 0.038 14.0 0.0 0.093 12.8 0.0 1.6 1 0 0 1 1 1 0 Valyl tRNA synthetase tRNA binding arm KTI12 PF08433.5 EIE85415.1 - 0.058 12.5 0.0 0.16 11.1 0.0 1.5 1 1 0 1 1 1 0 Chromatin associated protein KTI12 Oxysterol_BP PF01237.13 EIE85416.1 - 0.13 10.7 0.0 0.13 10.7 0.0 1.0 1 0 0 1 1 1 0 Oxysterol-binding protein Peptidase_S8 PF00082.17 EIE85418.1 - 1.2e-56 191.9 3.2 1.7e-56 191.4 2.3 1.1 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EIE85418.1 - 6.1e-15 55.5 0.1 1.1e-14 54.7 0.1 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 GUCT PF08152.7 EIE85418.1 - 0.02 14.8 0.1 3.2 7.8 0.0 2.6 3 0 0 3 3 3 0 GUCT (NUC152) domain Pkinase PF00069.20 EIE85419.1 - 2.4e-47 161.2 0.0 2.1e-46 158.1 0.0 2.4 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE85419.1 - 3.7e-22 78.6 0.0 6e-22 77.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EIE85419.1 - 1.1e-08 35.4 1.3 1.1e-08 35.4 0.9 2.3 2 0 0 2 2 2 1 Protein kinase C terminal domain PX PF00787.19 EIE85419.1 - 6.8e-07 29.0 6.5 4.1e-06 26.5 4.5 2.2 1 1 0 1 1 1 1 PX domain Kinase-like PF14531.1 EIE85419.1 - 5.3e-05 22.3 0.0 0.00011 21.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EIE85419.1 - 0.077 12.0 0.0 0.16 11.0 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family BTV_NS2 PF04514.7 EIE85419.1 - 0.34 9.7 7.1 0.56 9.0 4.9 1.4 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Tim54 PF11711.3 EIE85419.1 - 0.49 8.9 5.9 0.8 8.2 4.1 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Sporozoite_P67 PF05642.6 EIE85419.1 - 0.92 7.2 5.7 1.6 6.4 4.0 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen UDPGT PF00201.13 EIE85421.1 - 5.6e-09 35.0 0.0 7.7e-09 34.6 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_trans_1_3 PF13528.1 EIE85421.1 - 0.017 14.2 0.0 0.025 13.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 1 Glyco_tran_28_C PF04101.11 EIE85421.1 - 0.073 12.7 0.1 0.19 11.3 0.1 1.8 1 1 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Cpn60_TCP1 PF00118.19 EIE85422.1 - 6.3e-145 483.5 9.0 7.2e-145 483.3 6.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Nitro_FeMo-Co PF02579.12 EIE85422.1 - 0.01 15.8 0.1 0.26 11.3 0.0 3.2 3 0 0 3 3 3 0 Dinitrogenase iron-molybdenum cofactor DDE_3 PF13358.1 EIE85423.1 - 0.025 14.3 0.0 0.026 14.2 0.0 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease ACOX PF01756.14 EIE85424.1 - 9.2e-42 142.5 0.0 1.8e-41 141.5 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 EIE85424.1 - 1.8e-26 92.9 1.5 3.7e-26 91.8 1.0 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 EIE85424.1 - 1.5e-11 43.5 0.1 4.7e-11 42.0 0.1 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 EIE85424.1 - 2.4e-06 27.7 0.1 2.1e-05 24.6 0.0 2.6 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain HLH PF00010.21 EIE85425.1 - 1.8e-13 49.9 2.5 3.9e-13 48.8 1.8 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Myc-LZ PF02344.10 EIE85425.1 - 0.54 9.9 5.2 2.8 7.6 0.4 2.3 2 0 0 2 2 2 0 Myc leucine zipper domain PSP PF04046.11 EIE85426.1 - 0.032 13.6 0.0 0.036 13.4 0.0 1.2 1 0 0 1 1 1 0 PSP Piwi PF02171.12 EIE85427.1 - 1.9e-101 338.9 0.0 2.9e-101 338.4 0.0 1.3 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 EIE85427.1 - 2e-25 88.6 0.1 4.4e-25 87.5 0.1 1.6 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 EIE85427.1 - 1e-17 63.2 0.0 2.1e-17 62.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) DUF3959 PF13105.1 EIE85427.1 - 0.037 13.3 0.1 0.077 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) DDE_3 PF13358.1 EIE85428.1 - 1.2e-08 34.8 0.0 1.5e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease MTS PF05175.9 EIE85428.1 - 0.089 12.1 0.1 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain zf-CCHC PF00098.18 EIE85431.1 - 2.1e-10 39.9 8.0 1.3e-05 24.9 0.3 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 EIE85431.1 - 0.0006 19.4 4.0 0.05 13.2 0.3 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.1 EIE85431.1 - 1.4 8.4 4.4 0.78 9.2 0.3 2.3 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC_6 PF15288.1 EIE85431.1 - 1.8 8.3 8.4 0.11 12.2 1.5 2.3 1 1 1 2 2 2 0 Zinc knuckle RVT_1 PF00078.22 EIE85432.1 - 1.2e-36 126.0 0.0 3.1e-36 124.7 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.1 EIE85432.1 - 1.2e-06 28.6 4.5 4.3e-06 26.9 3.1 2.0 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Exo_endo_phos PF03372.18 EIE85432.1 - 0.0021 18.0 0.4 0.0048 16.8 0.3 1.7 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EIE85432.1 - 0.0034 16.9 0.5 0.0081 15.7 0.4 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase UPF0052 PF01933.13 EIE85434.1 - 8e-49 166.5 0.0 1e-48 166.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 Herpes_DNAp_acc PF04929.7 EIE85434.1 - 0.22 10.4 0.1 0.34 9.8 0.1 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DUF3808 PF10300.4 EIE85435.1 - 1.8e-49 168.5 2.2 1.8e-47 162.0 0.6 2.3 1 1 0 2 2 2 2 Protein of unknown function (DUF3808) TPR_12 PF13424.1 EIE85435.1 - 0.039 13.8 0.0 0.26 11.2 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 EIE85435.1 - 0.06 13.2 6.4 7.6 6.7 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat GAGA_bind PF06217.7 EIE85435.1 - 2 8.3 12.1 3.5 7.5 8.4 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family DUF500 PF04366.7 EIE85436.1 - 4e-44 149.0 0.3 7.2e-44 148.2 0.2 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF500) SH3_2 PF07653.12 EIE85436.1 - 8e-16 57.2 0.1 1.4e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EIE85436.1 - 1.3e-15 56.4 0.0 2.8e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EIE85436.1 - 3.2e-12 45.8 0.0 6.5e-12 44.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain IBR PF01485.16 EIE85437.1 - 1.6e-20 72.6 53.0 1.1e-10 41.2 10.0 4.5 3 1 1 4 4 4 2 IBR domain zf-C3HC4_2 PF13923.1 EIE85437.1 - 0.00015 21.7 12.3 0.00015 21.7 8.6 4.7 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIE85437.1 - 0.0014 18.3 8.9 0.0014 18.3 6.1 3.8 2 1 1 3 3 3 2 Ring finger domain Zn_Tnp_IS91 PF14319.1 EIE85437.1 - 0.0021 17.5 5.6 0.0021 17.5 3.9 4.1 3 1 1 4 4 4 1 Transposase zinc-binding domain zf-C3HC4 PF00097.20 EIE85437.1 - 0.0029 17.2 10.6 0.0029 17.2 7.3 4.8 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) PPR_2 PF13041.1 EIE85438.1 - 3.1e-10 39.8 0.3 0.00039 20.3 0.0 5.5 6 0 0 6 6 6 3 PPR repeat family PPR PF01535.15 EIE85438.1 - 0.004 17.0 2.0 14 5.9 0.0 6.3 7 0 0 7 7 7 1 PPR repeat Linker_histone PF00538.14 EIE85439.1 - 6.4e-22 77.4 0.2 6.4e-22 77.4 0.2 2.2 3 0 0 3 3 3 1 linker histone H1 and H5 family DUF1675 PF07897.6 EIE85439.1 - 2.2 8.0 21.2 2.6 7.8 14.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) DUF605 PF04652.11 EIE85440.1 - 0.97 8.7 13.9 1.3 8.3 9.6 1.2 1 0 0 1 1 1 0 Vta1 like Chitin_synth_2 PF03142.10 EIE85441.1 - 4.1e-243 807.5 1.6 5.8e-243 807.0 1.1 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 EIE85441.1 - 2.6e-115 386.0 9.3 4.4e-115 385.2 6.5 1.4 1 1 0 1 1 1 1 Myosin head (motor domain) Glyco_trans_2_3 PF13632.1 EIE85441.1 - 2.7e-18 66.3 0.5 1e-17 64.4 0.3 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 DEK_C PF08766.6 EIE85441.1 - 5.1e-18 64.5 0.3 1.6e-16 59.8 0.3 2.5 2 0 0 2 2 2 1 DEK C terminal domain Glyco_tranf_2_3 PF13641.1 EIE85441.1 - 1.2e-15 57.9 0.0 1.9e-13 50.7 0.0 2.5 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 EIE85441.1 - 2.7e-12 46.3 0.2 3.7e-07 29.8 0.0 2.7 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glycos_transf_2 PF00535.21 EIE85441.1 - 1.5e-05 24.7 0.0 0.00073 19.2 0.0 2.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EIE85441.1 - 8.6e-05 21.8 0.0 0.0018 17.5 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 21 AAA_22 PF13401.1 EIE85441.1 - 0.012 15.7 0.1 0.044 13.9 0.1 2.0 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 EIE85441.1 - 0.097 11.5 0.3 0.19 10.6 0.2 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein SNF2_N PF00176.18 EIE85442.1 - 6.8e-43 146.5 3.6 1.2e-39 135.9 0.3 2.4 1 1 1 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 EIE85442.1 - 9.2e-15 54.2 0.0 2.6e-14 52.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SnAC PF14619.1 EIE85442.1 - 7e-05 22.9 2.5 0.00033 20.7 0.7 3.0 2 0 0 2 2 2 1 Snf2-ATP coupling, chromatin remodelling complex Chromo PF00385.19 EIE85442.1 - 0.0011 18.6 3.7 0.0041 16.7 0.7 2.9 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain PHD PF00628.24 EIE85442.1 - 0.0029 17.2 26.3 0.02 14.5 7.1 2.7 2 0 0 2 2 2 2 PHD-finger C1_1 PF00130.17 EIE85442.1 - 0.054 13.2 26.6 0.22 11.2 4.1 3.0 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) NTP_transferase PF00483.18 EIE85443.1 - 9e-49 165.9 0.0 1.4e-48 165.3 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 EIE85443.1 - 4.4e-11 41.7 10.2 6.6e-09 34.8 2.4 3.7 1 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EIE85443.1 - 4.9e-11 42.9 0.0 6.7e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 EIE85443.1 - 2.2e-05 23.9 10.1 3.8e-05 23.1 3.6 3.4 3 1 1 4 4 4 1 Hexapeptide repeat of succinyl-transferase DUF2810 PF10928.3 EIE85443.1 - 0.015 15.0 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2810) CTP_transf_3 PF02348.14 EIE85443.1 - 0.023 14.3 0.1 0.045 13.3 0.0 1.5 1 1 0 1 1 1 0 Cytidylyltransferase PAH PF02671.16 EIE85445.1 - 1.3e-40 136.7 4.1 2.4e-17 62.2 0.8 3.7 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 EIE85445.1 - 6.6e-33 112.4 0.3 3.1e-32 110.3 0.2 2.2 1 0 0 1 1 1 1 Sin3 family co-repressor ADH_N PF08240.7 EIE85446.1 - 1e-26 92.7 7.8 1e-26 92.7 5.4 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIE85446.1 - 6.2e-18 64.6 0.0 9.5e-18 63.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EIE85446.1 - 0.00019 20.6 0.0 0.00088 18.4 0.0 1.9 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EIE85446.1 - 0.0046 16.5 0.0 0.0084 15.6 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_31 PF13847.1 EIE85446.1 - 0.02 14.4 0.0 0.1 12.2 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain ADH_zinc_N_2 PF13602.1 EIE85446.1 - 0.033 15.0 0.0 0.051 14.4 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase NAD_binding_2 PF03446.10 EIE85446.1 - 0.069 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase WD40 PF00400.27 EIE85447.1 - 3.2e-60 197.9 19.4 7.6e-11 41.4 0.4 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat BBS2_Mid PF14783.1 EIE85447.1 - 2.2e-08 33.8 0.2 0.12 12.1 0.0 4.9 2 2 3 5 5 5 2 Ciliary BBSome complex subunit 2, middle region eIF2A PF08662.6 EIE85447.1 - 4.1e-08 33.1 0.4 0.006 16.3 0.0 3.3 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 EIE85447.1 - 2.4e-06 26.5 6.8 0.045 12.4 0.4 3.5 1 1 2 3 3 3 3 Nup133 N terminal like Cytochrom_D1 PF02239.11 EIE85447.1 - 0.00011 20.6 0.1 0.0063 14.8 0.0 2.5 2 1 1 3 3 3 2 Cytochrome D1 heme domain PQQ_2 PF13360.1 EIE85447.1 - 0.00013 21.5 0.1 0.051 13.0 0.0 2.4 1 1 1 2 2 2 2 PQQ-like domain Kelch_6 PF13964.1 EIE85447.1 - 0.00034 20.6 0.2 2.6 8.3 0.0 3.9 4 0 0 4 4 4 1 Kelch motif PQQ_3 PF13570.1 EIE85447.1 - 0.0022 18.2 1.3 0.35 11.2 0.0 4.1 3 1 1 4 4 4 1 PQQ-like domain PD40 PF07676.7 EIE85447.1 - 0.0043 16.6 0.2 1.5 8.5 0.0 3.4 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Nup160 PF11715.3 EIE85447.1 - 0.0057 14.8 6.5 0.31 9.1 0.3 2.8 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Gmad1 PF10647.4 EIE85447.1 - 0.0064 15.9 0.2 0.86 8.9 0.2 2.9 2 1 0 2 2 2 1 Lipoprotein LpqB beta-propeller domain DUF3312 PF11768.3 EIE85447.1 - 0.011 13.9 0.2 8.1 4.5 0.0 3.2 1 1 3 4 4 4 0 Protein of unknown function (DUF3312) Neisseria_PilC PF05567.6 EIE85447.1 - 0.015 14.3 0.4 0.73 8.8 0.0 2.6 1 1 1 2 2 2 0 Neisseria PilC beta-propeller domain Cu-oxidase PF00394.17 EIE85447.1 - 0.078 12.8 0.0 1 9.2 0.0 2.2 2 0 0 2 2 2 0 Multicopper oxidase DHFR_2 PF06442.6 EIE85447.1 - 0.12 11.9 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 R67 dihydrofolate reductase Kelch_4 PF13418.1 EIE85448.1 - 2.6e-17 62.3 2.1 3.6e-06 26.6 0.0 5.0 4 1 0 4 4 4 3 Galactose oxidase, central domain Kelch_3 PF13415.1 EIE85448.1 - 1.3e-15 57.0 1.9 9.9e-06 25.5 0.1 5.6 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_6 PF13964.1 EIE85448.1 - 2.1e-15 56.1 0.5 0.00025 21.1 0.0 4.2 4 0 0 4 4 4 3 Kelch motif Kelch_5 PF13854.1 EIE85448.1 - 3.8e-15 55.4 0.0 2.3e-05 24.2 0.0 3.5 3 0 0 3 3 3 3 Kelch motif BTB PF00651.26 EIE85448.1 - 3.6e-09 36.5 0.2 8.1e-09 35.4 0.1 1.6 1 0 0 1 1 1 1 BTB/POZ domain Kelch_1 PF01344.20 EIE85448.1 - 8.3e-09 34.8 0.6 0.018 14.5 0.0 3.9 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 EIE85448.1 - 5.4e-05 22.7 0.5 0.76 9.6 0.0 3.8 4 0 0 4 4 4 2 Kelch motif Transp_cyt_pur PF02133.10 EIE85448.1 - 0.091 11.2 0.3 0.15 10.6 0.2 1.2 1 0 0 1 1 1 0 Permease for cytosine/purines, uracil, thiamine, allantoin DUF566 PF04484.7 EIE85449.1 - 8.4 5.8 15.0 11 5.4 10.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) DS PF01916.12 EIE85451.1 - 3.9e-141 469.4 0.0 4.5e-141 469.2 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase tRNA_m1G_MT PF01746.16 EIE85452.1 - 7.8e-27 94.0 0.2 8.6e-27 93.9 0.1 1.0 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase MMR_HSR1 PF01926.18 EIE85453.1 - 5.9e-19 68.1 0.0 9.8e-19 67.4 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.16 EIE85453.1 - 7.4e-15 54.5 0.0 1.4e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.13 EIE85453.1 - 2.2e-11 43.2 0.0 4.2e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 EIE85453.1 - 0.00027 21.4 0.0 0.0011 19.4 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 EIE85453.1 - 0.0017 18.1 1.8 0.14 11.9 0.0 2.6 2 1 0 3 3 3 1 Dynamin family SRPRB PF09439.5 EIE85453.1 - 0.0081 15.3 0.0 0.018 14.2 0.0 1.6 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.16 EIE85453.1 - 0.011 14.9 0.0 0.03 13.5 0.0 1.7 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_28 PF13521.1 EIE85453.1 - 0.012 15.5 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 EIE85453.1 - 0.022 13.5 0.1 0.042 12.6 0.0 1.5 1 0 0 1 1 1 0 ArgK protein AIG1 PF04548.11 EIE85453.1 - 0.039 13.0 0.0 0.087 11.9 0.0 1.6 1 0 0 1 1 1 0 AIG1 family MCM PF00493.18 EIE85453.1 - 0.043 12.6 0.0 0.071 11.8 0.0 1.2 1 0 0 1 1 1 0 MCM2/3/5 family DUF258 PF03193.11 EIE85453.1 - 0.066 12.4 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MobB PF03205.9 EIE85453.1 - 0.11 12.2 0.2 1.1 9.0 0.1 2.6 3 1 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 EIE85453.1 - 0.19 12.5 2.6 3.2 8.6 0.1 2.4 2 0 0 2 2 2 0 AAA domain EF-hand_1 PF00036.27 EIE85454.1 - 1.3e-17 61.6 9.7 5.2e-06 25.3 0.1 5.1 4 2 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 EIE85454.1 - 3.8e-17 60.5 4.6 5.1e-06 25.9 0.0 4.1 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.1 EIE85454.1 - 1.2e-15 57.3 4.8 4.1e-07 30.0 0.0 3.2 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.1 EIE85454.1 - 1.1e-12 47.3 5.7 3e-06 26.7 0.1 3.9 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 EIE85454.1 - 9.5e-11 40.5 6.1 0.0013 17.9 0.0 3.9 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.1 EIE85454.1 - 0.0064 16.3 0.0 0.2 11.5 0.0 2.7 3 1 0 3 3 3 1 EF-hand domain DUF3164 PF11363.3 EIE85454.1 - 0.025 13.9 1.1 10 5.4 0.0 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3164) COX7a PF02238.10 EIE85455.1 - 0.00021 20.9 0.0 0.00025 20.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIa DUF3318 PF11780.3 EIE85455.1 - 0.053 13.1 0.0 0.059 12.9 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3318) Ribosomal_L23eN PF03939.8 EIE85456.1 - 2.7e-19 68.9 10.1 5.7e-19 67.9 7.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.15 EIE85456.1 - 3.2e-19 68.6 2.9 3.2e-19 68.6 2.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L23 Ribosomal_L7Ae PF01248.21 EIE85457.1 - 1.1e-28 98.5 1.1 1.4e-28 98.2 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Adeno_E3A PF05248.7 EIE85457.1 - 0.037 14.0 0.1 0.048 13.7 0.0 1.3 1 0 0 1 1 1 0 Adenovirus E3A FliM PF02154.10 EIE85457.1 - 0.072 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Flagellar motor switch protein FliM DUF2096 PF09869.4 EIE85457.1 - 0.14 12.0 0.2 0.22 11.4 0.1 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2096) DnaJ PF00226.26 EIE85458.1 - 2.2e-22 78.5 0.4 4.4e-22 77.5 0.3 1.5 1 0 0 1 1 1 1 DnaJ domain PLDc_3 PF13918.1 EIE85458.1 - 0.041 13.3 0.0 0.074 12.4 0.0 1.4 1 0 0 1 1 1 0 PLD-like domain ERG4_ERG24 PF01222.12 EIE85459.1 - 3.9e-72 243.1 8.3 3.4e-67 226.8 4.1 2.0 1 1 1 2 2 2 2 Ergosterol biosynthesis ERG4/ERG24 family TIR PF01582.15 EIE85461.1 - 0.046 13.1 0.0 0.059 12.8 0.0 1.2 1 0 0 1 1 1 0 TIR domain DUF4168 PF13767.1 EIE85462.1 - 0.087 13.4 0.2 0.11 13.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4168) Ca_chan_IQ PF08763.6 EIE85463.1 - 1 8.6 10.3 0.089 12.0 3.6 1.7 2 0 0 2 2 2 0 Voltage gated calcium channel IQ domain PT PF04886.7 EIE85464.1 - 3.6e-07 29.3 43.1 1.5e+04 -11.7 29.9 3.3 1 1 0 1 1 1 0 PT repeat Cornifin PF02389.10 EIE85464.1 - 0.00035 20.4 7.6 0.0004 20.2 5.3 1.1 1 0 0 1 1 1 1 Cornifin (SPRR) family DDE_3 PF13358.1 EIE85467.1 - 0.00096 18.9 0.2 0.0028 17.4 0.1 1.9 1 1 0 1 1 1 1 DDE superfamily endonuclease TMEM247 PF15444.1 EIE85470.1 - 0.13 12.0 1.5 0.2 11.4 1.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 247 rve PF00665.21 EIE85471.1 - 2.4e-21 76.0 0.0 8.5e-21 74.2 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 EIE85471.1 - 5e-06 26.0 0.0 1e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Dapper PF15268.1 EIE85472.1 - 0.054 12.2 1.0 0.057 12.2 0.7 1.0 1 0 0 1 1 1 0 Dapper Aldedh PF00171.17 EIE85473.1 - 1.4e-182 607.1 0.0 1.6e-182 606.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EIE85473.1 - 0.0032 16.7 0.0 2.4 7.3 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) LuxC PF05893.9 EIE85473.1 - 0.0074 15.0 0.0 0.031 12.9 0.0 1.9 2 1 1 3 3 3 1 Acyl-CoA reductase (LuxC) PCP PF02429.10 EIE85473.1 - 0.047 13.7 0.2 0.047 13.7 0.1 2.0 3 0 0 3 3 3 0 Peridinin-chlorophyll A binding protein TPR_11 PF13414.1 EIE85474.1 - 7.6e-32 108.7 17.6 4e-18 64.8 0.2 4.5 3 2 3 6 6 6 4 TPR repeat TPR_1 PF00515.23 EIE85474.1 - 7.4e-29 98.1 13.4 1.9e-06 27.2 0.0 6.6 5 1 1 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.12 EIE85474.1 - 1.3e-20 71.6 14.4 0.00035 20.2 0.2 6.6 5 1 1 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.1 EIE85474.1 - 8.4e-11 41.6 12.8 0.002 18.0 0.7 5.4 1 1 5 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.1 EIE85474.1 - 1.2e-09 37.2 4.3 0.0004 19.9 0.0 4.9 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 EIE85474.1 - 8.2e-09 35.6 9.9 0.011 16.0 0.2 5.4 3 2 3 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 EIE85474.1 - 1e-08 34.6 7.6 0.047 13.8 0.1 6.1 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 EIE85474.1 - 1.4e-08 34.6 1.3 0.3 11.8 0.0 6.1 2 2 5 7 7 7 1 Tetratricopeptide repeat TPR_8 PF13181.1 EIE85474.1 - 1.9e-08 33.4 17.7 0.00012 21.6 0.2 5.3 6 0 0 6 6 5 3 Tetratricopeptide repeat Apc3 PF12895.2 EIE85474.1 - 2.3e-08 34.0 7.6 3.8e-05 23.7 1.4 3.1 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EIE85474.1 - 4.2e-08 33.6 5.8 0.0071 17.0 0.0 4.8 2 2 1 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 EIE85474.1 - 0.00027 20.7 4.7 0.24 11.2 0.0 4.4 2 1 3 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 EIE85474.1 - 0.00032 20.9 6.5 0.97 10.0 0.0 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.1 EIE85474.1 - 0.0011 18.7 0.3 6.9 6.7 0.0 3.9 3 1 1 4 4 3 1 Tetratricopeptide repeat Peptidase_M74 PF03411.8 EIE85474.1 - 0.047 12.8 0.0 0.076 12.2 0.0 1.3 1 0 0 1 1 1 0 Penicillin-insensitive murein endopeptidase Poxvirus PF06227.7 EIE85474.1 - 0.056 12.9 0.4 0.12 11.9 0.2 1.6 1 1 0 1 1 1 0 dsDNA Poxvirus PSD4 PF07631.6 EIE85474.1 - 0.063 13.6 3.1 5.6 7.3 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1592) Acetyltransf_11 PF13720.1 EIE85474.1 - 0.07 13.3 0.6 0.26 11.5 0.1 2.4 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 FKBP_N PF01346.13 EIE85474.1 - 0.17 11.9 9.2 0.93 9.5 0.4 2.8 2 1 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase MIT PF04212.13 EIE85474.1 - 0.58 10.0 8.4 4 7.3 0.0 4.6 4 1 0 4 4 4 0 MIT (microtubule interacting and transport) domain V_ATPase_I PF01496.14 EIE85474.1 - 1 7.1 3.8 1.2 6.9 2.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cyclin PF08613.6 EIE85475.1 - 3.9e-16 59.7 3.8 7.4e-16 58.8 2.6 1.6 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EIE85475.1 - 8.5e-05 22.1 2.3 0.00016 21.1 1.5 1.6 1 1 0 1 1 1 1 Cyclin, N-terminal domain Arrestin_N PF00339.24 EIE85476.1 - 2.1e-08 34.1 0.0 1.1e-06 28.5 0.0 2.8 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EIE85476.1 - 2.7e-07 30.7 8.1 1.9e-06 28.0 0.1 3.6 2 2 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain LRR_8 PF13855.1 EIE85477.1 - 9.4e-30 102.1 39.6 8.9e-09 34.9 0.6 5.0 2 1 5 7 7 7 6 Leucine rich repeat LRR_4 PF12799.2 EIE85477.1 - 1.5e-27 94.7 14.5 9.6e-09 34.6 0.0 5.9 5 1 0 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EIE85477.1 - 5.9e-19 65.1 22.5 0.014 15.3 0.5 9.9 11 0 0 11 11 11 6 Leucine Rich Repeat LRR_7 PF13504.1 EIE85477.1 - 1.3e-10 39.7 18.4 0.046 13.9 0.1 8.3 8 0 0 8 8 8 4 Leucine rich repeat LRR_6 PF13516.1 EIE85477.1 - 1.9e-10 39.7 9.0 0.55 10.4 0.0 7.4 7 0 0 7 7 7 3 Leucine Rich repeat LRR_9 PF14580.1 EIE85477.1 - 4.1e-05 23.2 1.0 0.026 14.0 0.0 2.6 2 1 0 2 2 2 2 Leucine-rich repeat DUF2256 PF10013.4 EIE85477.1 - 1 9.1 3.4 6.7 6.5 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) LRR_3 PF07725.7 EIE85477.1 - 2.9 7.8 11.1 24 4.9 0.0 4.6 4 0 0 4 4 4 0 Leucine Rich Repeat Yae1_N PF09811.4 EIE85478.1 - 2.8e-12 45.9 4.5 3.7e-12 45.5 3.1 1.2 1 0 0 1 1 1 1 Essential protein Yae1, N terminal COX5A PF02284.11 EIE85479.1 - 1.7e-41 140.5 0.1 2.1e-41 140.2 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va Tricorn_C1 PF14684.1 EIE85479.1 - 0.063 13.1 0.1 0.2 11.5 0.0 1.8 2 0 0 2 2 2 0 Tricorn protease C1 domain UPF0061 PF02696.9 EIE85480.1 - 3.9e-78 262.9 6.5 3.8e-52 177.1 1.6 2.9 1 1 1 2 2 2 2 Uncharacterized ACR, YdiU/UPF0061 family E1-E2_ATPase PF00122.15 EIE85481.1 - 5.3e-57 192.4 1.5 5.3e-57 192.4 1.1 2.2 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EIE85481.1 - 1.5e-42 145.1 11.5 1.5e-42 145.1 8.0 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EIE85481.1 - 2.5e-30 106.5 0.0 5.6e-30 105.3 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EIE85481.1 - 7.8e-22 77.0 0.0 1.5e-21 76.1 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EIE85481.1 - 2.3e-14 53.9 0.0 4.9e-14 52.9 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EIE85481.1 - 2e-08 33.5 0.1 2.2e-07 30.2 0.0 2.5 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EIE85481.1 - 8.5e-05 22.2 0.5 0.00057 19.5 0.2 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase EF-hand_7 PF13499.1 EIE85482.1 - 4.7e-11 42.6 5.2 3.2e-05 23.9 0.2 2.8 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EIE85482.1 - 4.6e-10 38.0 12.5 0.00021 20.3 0.6 5.5 5 1 1 6 6 6 2 EF hand EF-hand_6 PF13405.1 EIE85482.1 - 4.8e-08 32.2 7.1 0.0027 17.4 0.3 4.1 5 0 0 5 5 5 2 EF-hand domain EF-hand_5 PF13202.1 EIE85482.1 - 6.1e-06 25.3 3.1 0.0039 16.4 0.7 3.2 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 EIE85482.1 - 8e-05 22.1 13.3 0.00013 21.5 0.5 3.9 2 1 3 5 5 5 2 EF-hand domain pair EF-hand_9 PF14658.1 EIE85482.1 - 0.014 15.2 0.1 3.8 7.5 0.0 2.9 2 2 0 2 2 2 0 EF-hand domain p25-alpha PF05517.7 EIE85482.1 - 0.023 14.9 0.4 0.054 13.7 0.1 1.8 1 1 1 2 2 2 0 p25-alpha UPF0154 PF03672.8 EIE85482.1 - 0.13 11.9 0.0 14 5.3 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) B12-binding_2 PF02607.12 EIE85482.1 - 0.13 12.2 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 B12 binding domain cNMP_binding PF00027.24 EIE85483.1 - 1.3e-43 146.7 0.0 5.7e-21 74.1 0.0 5.4 5 0 0 5 5 5 5 Cyclic nucleotide-binding domain Patatin PF01734.17 EIE85483.1 - 5e-19 69.0 6.4 1.2e-17 64.5 4.4 2.9 1 1 0 1 1 1 1 Patatin-like phospholipase Dynamin_N PF00350.18 EIE85483.1 - 0.025 14.4 0.1 0.072 12.8 0.0 1.8 1 0 0 1 1 1 0 Dynamin family CDC45 PF02724.9 EIE85483.1 - 0.15 10.0 1.2 0.31 9.0 0.8 1.4 1 0 0 1 1 1 0 CDC45-like protein DUF2130 PF09903.4 EIE85484.1 - 0.0014 17.4 0.8 0.002 16.8 0.6 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2130) Glyco_hydro_16 PF00722.16 EIE85485.1 - 5.7e-11 42.0 0.2 3.3e-10 39.5 0.0 2.0 1 1 1 2 2 2 1 Glycosyl hydrolases family 16 Glycos_transf_4 PF00953.16 EIE85486.1 - 1.9e-07 31.0 0.2 1.9e-07 31.0 0.1 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 4 DNA_pol_A PF00476.15 EIE85487.1 - 1.5e-92 310.1 0.0 1.9e-92 309.8 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family A Peroxin-13_N PF04088.8 EIE85488.1 - 6.6e-41 139.8 0.0 9.9e-41 139.3 0.0 1.2 1 0 0 1 1 1 1 Peroxin 13, N-terminal region Response_reg PF00072.19 EIE85489.1 - 8.9e-26 90.1 0.2 1.4e-25 89.5 0.1 1.3 1 0 0 1 1 1 1 Response regulator receiver domain RRM_1 PF00076.17 EIE85490.1 - 2.9e-37 126.1 0.0 4.1e-18 64.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE85490.1 - 4e-22 77.9 0.0 5.5e-10 39.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE85490.1 - 3.9e-17 61.8 0.0 2e-08 33.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 EIE85490.1 - 0.0014 18.1 0.1 0.024 14.1 0.0 2.3 2 0 0 2 2 2 1 Ribonuclease B OB domain Limkain-b1 PF11608.3 EIE85490.1 - 0.0079 15.9 0.0 1.2 8.9 0.0 2.2 2 0 0 2 2 2 2 Limkain b1 EPSP_synthase PF00275.15 EIE85491.1 - 3.2e-112 375.0 0.5 2.2e-83 280.0 0.2 2.2 1 1 1 2 2 2 2 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 EIE85491.1 - 3.3e-93 311.3 0.0 1e-92 309.7 0.0 1.8 2 0 0 2 2 2 1 3-dehydroquinate synthase DHquinase_I PF01487.10 EIE85491.1 - 1.9e-60 204.2 0.0 3.8e-60 203.3 0.0 1.5 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 EIE85491.1 - 1.3e-36 125.8 0.0 3.5e-36 124.4 0.0 1.7 1 0 0 1 1 1 1 Shikimate kinase Shikimate_dh_N PF08501.6 EIE85491.1 - 1e-24 86.3 0.0 3.2e-24 84.7 0.0 1.9 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 EIE85491.1 - 1.7e-12 47.6 0.0 4.2e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.1 EIE85491.1 - 6.1e-07 28.9 0.0 2.2e-06 27.1 0.0 2.1 2 1 0 2 2 2 1 Iron-containing alcohol dehydrogenase AAA_17 PF13207.1 EIE85491.1 - 1.4e-06 29.0 0.1 9.9e-06 26.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EIE85491.1 - 0.0043 17.3 0.0 0.017 15.4 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EIE85491.1 - 0.022 14.6 0.0 0.053 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EIE85491.1 - 0.06 13.2 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EIE85491.1 - 0.064 12.8 1.1 0.52 9.8 0.0 2.5 3 0 0 3 3 3 0 AAA domain Arch_ATPase PF01637.13 EIE85491.1 - 0.083 12.5 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase YlzJ PF14035.1 EIE85491.1 - 0.12 12.4 0.0 6.9 6.7 0.1 2.8 2 0 0 2 2 2 0 YlzJ-like protein DUF3585 PF12130.3 EIE85491.1 - 0.26 11.1 0.1 0.8 9.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3585) RAB3GAP2_N PF14655.1 EIE85492.1 - 0.57 9.1 4.7 1.2 8.0 1.3 2.4 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Apolipoprotein PF01442.13 EIE85493.1 - 0.0036 16.8 2.5 0.0044 16.5 1.8 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF2408 PF10303.4 EIE85493.1 - 0.006 16.7 3.3 0.085 12.9 2.3 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF2408) Phage_lysis PF03245.8 EIE85493.1 - 0.017 15.0 4.1 0.025 14.5 2.8 1.4 1 1 0 1 1 1 0 Bacteriophage Rz lysis protein Tmemb_cc2 PF10267.4 EIE85493.1 - 0.048 12.2 1.9 0.058 11.9 1.3 1.3 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DUF932 PF06067.6 EIE85493.1 - 0.1 11.9 0.2 0.11 11.8 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF932) FmrO PF07091.6 EIE85493.1 - 0.13 11.1 0.6 0.14 11.0 0.4 1.0 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) GreA_GreB_N PF03449.10 EIE85493.1 - 0.22 11.5 2.0 0.35 10.9 0.5 2.0 1 1 1 2 2 2 0 Transcription elongation factor, N-terminal tRNA-synt_2b PF00587.20 EIE85494.1 - 6e-35 120.3 0.0 1.1e-34 119.5 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EIE85494.1 - 5.3e-23 81.0 7.5 5.3e-23 81.0 5.2 1.8 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain Pox_F11 PF04943.7 EIE85494.1 - 0.044 12.6 1.1 0.063 12.1 0.8 1.2 1 0 0 1 1 1 0 Poxvirus F11 protein BOFC_N PF08977.5 EIE85494.1 - 0.07 12.9 0.1 0.25 11.1 0.1 1.9 1 0 0 1 1 1 0 Bypass of Forespore C, N terminal DUF1842 PF08896.5 EIE85495.1 - 0.12 12.0 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1842) DUF457 PF04307.9 EIE85496.1 - 5.5 6.3 7.2 8.3 5.7 5.0 1.3 1 0 0 1 1 1 0 Predicted membrane-bound metal-dependent hydrolase (DUF457) Abhydrolase_1 PF00561.15 EIE85497.1 - 1.8e-08 34.2 0.0 2.6e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EIE85497.1 - 3e-08 33.8 0.0 5.1e-08 33.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIE85497.1 - 1.1e-05 25.2 0.0 4.5e-05 23.2 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EIE85497.1 - 0.02 14.7 0.0 0.059 13.2 0.0 1.8 1 0 0 1 1 1 0 Putative lysophospholipase PEPcase PF00311.12 EIE85498.1 - 0.0015 16.4 10.3 0.0024 15.7 7.2 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase DUF3498 PF12004.3 EIE85498.1 - 0.99 8.4 21.2 0.13 11.3 0.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3498) PIN_2 PF10130.4 EIE85498.1 - 4.3 7.3 9.0 0.98 9.4 0.1 3.0 2 2 1 3 3 3 0 PIN domain Chromo PF00385.19 EIE85505.1 - 1e-08 34.7 1.7 4e-08 32.7 0.5 2.0 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Transposase_21 PF02992.9 EIE85507.1 - 1.5e-21 76.5 0.3 5.1e-21 74.8 0.0 1.9 2 0 0 2 2 2 1 Transposase family tnp2 DUF1258 PF06869.7 EIE85507.1 - 0.0054 15.8 0.0 0.011 14.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) DDE_3 PF13358.1 EIE85510.1 - 4.2e-14 52.5 0.1 5e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE85510.1 - 0.003 17.6 0.0 0.0036 17.4 0.0 1.3 1 1 0 1 1 1 1 Integrase core domain rve PF00665.21 EIE85512.1 - 1.2e-16 60.9 0.0 4.8e-16 58.9 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE85512.1 - 3.9e-11 42.7 0.6 3.6e-10 39.5 0.3 2.7 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE85512.1 - 2.7e-08 33.3 2.9 9.8e-08 31.5 0.1 2.9 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain RVP PF00077.15 EIE85512.1 - 0.0021 17.9 0.1 0.0088 15.9 0.1 2.2 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 EIE85512.1 - 0.0041 17.5 0.1 0.0091 16.4 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.12 EIE85512.1 - 0.025 14.6 0.0 0.25 11.4 0.0 2.7 2 0 0 2 2 2 0 Retrotransposon gag protein DDE_3 PF13358.1 EIE85514.1 - 8.9e-14 51.4 0.0 1.4e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF2567 PF10821.3 EIE85514.1 - 0.0068 15.9 0.0 0.0094 15.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2567) DUF1759 PF03564.10 EIE85515.1 - 0.0023 17.7 0.2 0.0067 16.2 0.2 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) DDE_3 PF13358.1 EIE85516.1 - 2.7e-13 49.8 0.0 5.8e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF2567 PF10821.3 EIE85516.1 - 0.18 11.3 0.0 0.27 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2567) MRL1 PF13003.2 EIE85517.1 - 0.0057 16.4 0.1 0.0072 16.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L1 Fijivirus_P9-2 PF06837.6 EIE85517.1 - 0.089 11.9 0.1 0.089 11.9 0.1 1.0 1 0 0 1 1 1 0 Fijivirus P9-2 protein HTH_Tnp_Tc3_2 PF01498.13 EIE85518.1 - 1.3e-07 31.5 0.4 4e-07 30.0 0.1 2.0 2 0 0 2 2 2 1 Transposase Cwf_Cwc_15 PF04889.7 EIE85519.1 - 1.1 8.8 15.1 0.11 12.1 6.1 2.0 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein rve PF00665.21 EIE85520.1 - 1.5e-07 31.5 0.2 4.3e-07 30.0 0.0 1.9 2 1 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.5 EIE85520.1 - 0.0047 16.3 1.0 0.012 14.9 0.1 2.1 2 0 0 2 2 2 1 His(2)-Cys(2) zinc finger DUF438 PF04282.8 EIE85520.1 - 0.027 14.2 0.0 0.076 12.8 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF438) HTH_Tnp_Tc3_2 PF01498.13 EIE85521.1 - 2.2e-08 34.0 0.3 2.2e-08 34.0 0.2 2.1 1 1 0 2 2 2 1 Transposase HTH_29 PF13551.1 EIE85521.1 - 0.0002 21.4 1.9 0.00041 20.4 1.3 1.6 1 1 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_ISL3 PF13542.1 EIE85521.1 - 0.0033 16.5 1.7 0.016 14.3 0.5 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_32 PF13565.1 EIE85521.1 - 0.012 16.4 1.5 0.025 15.3 0.4 2.0 2 1 0 2 2 2 0 Homeodomain-like domain HTH_12 PF08461.5 EIE85521.1 - 0.048 13.3 0.1 0.14 11.9 0.1 1.7 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain HTH_23 PF13384.1 EIE85521.1 - 0.062 12.9 2.9 1.2 8.9 0.2 2.5 2 0 0 2 2 2 0 Homeodomain-like domain DUF4330 PF14221.1 EIE85521.1 - 0.071 12.9 0.1 0.089 12.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4330) HTH_Tnp_1 PF01527.15 EIE85521.1 - 0.076 12.9 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Transposase HTH_21 PF13276.1 EIE85521.1 - 0.1 12.6 3.2 0.41 10.7 0.1 2.3 2 0 0 2 2 2 0 HTH-like domain rve PF00665.21 EIE85522.1 - 6.3e-19 68.2 0.0 1.1e-18 67.5 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain HTH_22 PF13309.1 EIE85522.1 - 0.00054 19.6 0.0 0.0049 16.5 0.0 2.6 3 0 0 3 3 3 1 HTH domain rve_3 PF13683.1 EIE85522.1 - 0.027 13.9 0.0 0.057 12.9 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain RVT_1 PF00078.22 EIE85523.1 - 7.7e-20 71.1 0.0 1.3e-19 70.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.12 EIE85523.1 - 2.8e-08 33.6 0.2 6.2e-08 32.6 0.2 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein Asp_protease_2 PF13650.1 EIE85523.1 - 1.1e-07 32.2 0.0 2.6e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.18 EIE85523.1 - 0.00092 19.0 1.3 0.0019 18.0 0.9 1.5 1 0 0 1 1 1 1 Zinc knuckle gag-asp_proteas PF13975.1 EIE85523.1 - 0.0048 16.6 0.0 0.013 15.2 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 EIE85523.1 - 0.022 14.6 0.0 0.045 13.6 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease RVP PF00077.15 EIE85523.1 - 0.048 13.5 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease DDE_3 PF13358.1 EIE85524.1 - 3.2e-29 101.5 0.0 7.2e-29 100.4 0.0 1.6 1 1 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.14 EIE85524.1 - 0.00013 21.2 0.0 0.00026 20.2 0.0 1.5 1 1 0 1 1 1 1 DDE superfamily endonuclease AAA_28 PF13521.1 EIE85524.1 - 0.086 12.8 0.1 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain DDE_3 PF13358.1 EIE85525.1 - 2.9e-20 72.4 0.0 5.7e-20 71.5 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE85525.1 - 9.9e-16 57.5 1.9 2.8e-15 56.1 0.3 2.4 3 0 0 3 3 2 1 Transposase HTH_29 PF13551.1 EIE85525.1 - 2.7e-06 27.4 0.2 8.6e-06 25.8 0.2 1.9 2 0 0 2 2 1 1 Winged helix-turn helix HTH_38 PF13936.1 EIE85525.1 - 1.2e-05 24.7 0.1 3.3e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.1 EIE85525.1 - 8.1e-05 22.1 0.1 0.0028 17.2 0.0 2.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.1 EIE85525.1 - 8.9e-05 23.2 2.8 0.02 15.6 0.1 3.7 4 0 0 4 4 4 1 Homeodomain-like domain HTH_21 PF13276.1 EIE85525.1 - 0.001 18.9 0.1 0.13 12.2 0.0 3.0 3 0 0 3 3 3 1 HTH-like domain HTH_28 PF13518.1 EIE85525.1 - 0.0013 18.6 0.0 0.0056 16.6 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.7 EIE85525.1 - 0.0016 17.8 0.5 0.024 14.0 0.0 2.6 3 0 0 3 3 3 1 Sigma-70, region 4 HTH_7 PF02796.10 EIE85525.1 - 0.0023 17.7 1.1 0.1 12.4 0.0 2.8 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase rve PF00665.21 EIE85525.1 - 0.0054 16.8 0.0 0.017 15.2 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain LacI PF00356.16 EIE85525.1 - 0.018 14.6 1.7 2.8 7.6 0.2 2.7 3 0 0 3 3 3 0 Bacterial regulatory proteins, lacI family HTH_Tnp_4 PF13613.1 EIE85525.1 - 0.023 14.2 0.1 0.057 12.9 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_36 PF13730.1 EIE85525.1 - 0.055 13.6 0.4 4.1 7.6 0.0 3.2 3 0 0 3 3 2 0 Helix-turn-helix domain CPSase_L_D3 PF02787.14 EIE85525.1 - 0.059 13.1 0.0 0.14 11.8 0.0 1.6 2 0 0 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain HTH_Tnp_ISL3 PF13542.1 EIE85525.1 - 0.17 11.0 2.8 8.4 5.6 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 HTH_17 PF12728.2 EIE85525.1 - 0.18 12.0 0.9 15 5.9 0.1 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_29 PF13551.1 EIE85526.1 - 0.00039 20.5 0.2 0.00074 19.6 0.1 1.3 1 1 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EIE85526.1 - 0.0004 19.9 0.1 0.015 14.9 0.0 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_17 PF12728.2 EIE85526.1 - 0.005 17.0 0.1 0.018 15.2 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.13 EIE85526.1 - 0.018 15.0 1.3 0.14 12.2 0.1 2.3 2 1 0 2 2 2 0 Transposase HTH_32 PF13565.1 EIE85526.1 - 0.026 15.3 0.2 0.12 13.2 0.1 1.9 1 1 1 2 2 2 0 Homeodomain-like domain HTH_28 PF13518.1 EIE85526.1 - 0.068 13.1 0.2 0.18 11.8 0.0 1.8 1 1 1 2 2 2 0 Helix-turn-helix domain HTH_IclR PF09339.5 EIE85526.1 - 0.11 12.1 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_40 PF14493.1 EIE85526.1 - 0.12 12.6 0.4 0.24 11.6 0.1 1.6 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_5 PF01022.15 EIE85526.1 - 0.13 11.9 1.1 0.99 9.1 0.1 2.2 2 1 0 2 2 2 0 Bacterial regulatory protein, arsR family DDE_3 PF13358.1 EIE85527.1 - 1.3e-16 60.6 2.6 1.6e-16 60.3 0.7 1.9 2 1 0 2 2 2 1 DDE superfamily endonuclease BrkDBD PF09607.5 EIE85527.1 - 0.091 12.3 1.0 1.4 8.5 0.0 2.4 2 0 0 2 2 2 0 Brinker DNA-binding domain HTH_Tnp_Tc3_2 PF01498.13 EIE85529.1 - 2.8e-07 30.5 0.7 5.8e-07 29.4 0.1 1.8 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 EIE85529.1 - 0.001 19.1 0.1 0.0026 17.8 0.1 1.6 2 1 0 2 2 2 1 Winged helix-turn helix HTH_17 PF12728.2 EIE85529.1 - 0.037 14.2 0.0 0.062 13.5 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain FCH PF00611.18 EIE85530.1 - 2.9e-13 49.8 2.2 2.9e-13 49.8 1.5 2.7 3 1 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 EIE85530.1 - 6.1e-11 41.5 0.2 1.4e-10 40.4 0.2 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EIE85530.1 - 1.6e-10 40.3 0.9 2.6e-10 39.7 0.1 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 EIE85530.1 - 2.6e-09 36.4 0.1 8.6e-09 34.7 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain BAR PF03114.13 EIE85530.1 - 0.00091 18.8 7.7 0.00091 18.8 5.3 2.0 2 0 0 2 2 2 1 BAR domain CP12 PF02672.10 EIE85532.1 - 0.1 13.0 0.4 0.3 11.5 0.3 1.8 1 0 0 1 1 1 0 CP12 domain adh_short PF00106.20 EIE85534.1 - 6.9e-27 94.3 0.0 1.3e-26 93.5 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIE85534.1 - 6.3e-14 52.3 0.0 8.5e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIE85534.1 - 2.4e-08 33.8 0.0 3.5e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EIE85534.1 - 0.0043 16.5 0.2 0.0069 15.8 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EIE85534.1 - 0.0065 16.2 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase SHS2_Rpb7-N PF03876.12 EIE85534.1 - 0.12 12.4 0.1 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 NAD_binding_10 PF13460.1 EIE85534.1 - 0.14 12.1 0.4 1 9.3 0.2 2.2 1 1 0 1 1 1 0 NADH(P)-binding Pex14_N PF04695.8 EIE85535.1 - 1.1e-29 103.1 0.3 1.1e-29 103.1 0.2 3.8 2 2 1 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region IncA PF04156.9 EIE85535.1 - 0.00012 21.7 0.2 0.00018 21.1 0.2 1.3 1 0 0 1 1 1 1 IncA protein AAA_13 PF13166.1 EIE85535.1 - 0.0014 17.1 6.9 0.0021 16.6 4.8 1.1 1 0 0 1 1 1 1 AAA domain DUF4407 PF14362.1 EIE85535.1 - 0.0044 16.0 0.3 0.0054 15.7 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) DUF2681 PF10883.3 EIE85535.1 - 0.0095 16.1 0.6 0.02 15.0 0.0 1.8 2 0 0 2 2 1 1 Protein of unknown function (DUF2681) Bul1_C PF04426.7 EIE85535.1 - 0.013 14.7 2.0 0.02 14.1 1.4 1.3 1 0 0 1 1 1 0 Bul1 C terminus Ran-binding PF05508.6 EIE85535.1 - 0.017 14.0 2.6 0.025 13.4 1.8 1.1 1 0 0 1 1 1 0 RanGTP-binding protein Dor1 PF04124.7 EIE85535.1 - 0.032 12.6 7.4 0.047 12.1 5.1 1.1 1 0 0 1 1 1 0 Dor1-like family DUF3584 PF12128.3 EIE85535.1 - 0.044 11.1 7.2 0.061 10.6 5.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) CR6_interact PF10147.4 EIE85535.1 - 0.052 12.8 5.0 0.095 12.0 3.5 1.3 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 DUF4200 PF13863.1 EIE85535.1 - 0.074 12.9 11.0 0.1 12.5 7.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) APG17 PF04108.7 EIE85535.1 - 0.078 11.7 8.1 0.12 11.1 5.6 1.2 1 0 0 1 1 1 0 Autophagy protein Apg17 DUF2524 PF10732.4 EIE85535.1 - 0.092 12.8 5.3 0.16 12.1 3.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2524) NPV_P10 PF05531.7 EIE85535.1 - 0.1 12.8 9.8 0.31 11.3 2.7 2.6 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.7 EIE85535.1 - 0.1 12.4 8.9 0.11 12.2 1.6 1.8 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2408 PF10303.4 EIE85535.1 - 0.14 12.2 7.4 0.43 10.7 4.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) COG2 PF06148.6 EIE85535.1 - 0.16 11.8 5.9 0.43 10.4 4.0 1.8 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DMAP_binding PF06464.6 EIE85535.1 - 0.32 11.6 6.3 0.78 10.3 4.4 1.6 1 0 0 1 1 1 0 DMAP1-binding Domain NYD-SP28 PF14772.1 EIE85535.1 - 0.36 10.9 8.0 0.73 9.9 5.6 1.4 1 0 0 1 1 1 0 Sperm tail TMPIT PF07851.8 EIE85535.1 - 0.37 9.8 6.9 0.53 9.3 4.8 1.1 1 0 0 1 1 1 0 TMPIT-like protein RmuC PF02646.11 EIE85535.1 - 0.42 9.4 7.8 0.38 9.5 4.1 1.7 1 1 1 2 2 2 0 RmuC family Baculo_p24 PF05073.7 EIE85535.1 - 0.44 10.1 5.1 0.67 9.4 3.5 1.2 1 0 0 1 1 1 0 Baculovirus P24 capsid protein TBPIP PF07106.8 EIE85535.1 - 0.66 9.4 11.0 1.1 8.8 7.6 1.3 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF342 PF03961.8 EIE85535.1 - 0.67 8.3 5.4 1 7.6 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF2317 PF10079.4 EIE85535.1 - 1 7.8 7.8 2 6.9 5.4 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) Phage_GPO PF05929.6 EIE85535.1 - 1.1 8.3 7.7 1.7 7.7 5.4 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Fmp27_WPPW PF10359.4 EIE85535.1 - 1.3 7.3 9.0 2 6.7 6.2 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Sec20 PF03908.8 EIE85535.1 - 1.3 8.7 5.3 2 8.1 3.0 1.8 1 1 0 1 1 1 0 Sec20 DUF3829 PF12889.2 EIE85535.1 - 1.8 7.6 9.9 4.6 6.3 7.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3829) DUF1664 PF07889.7 EIE85535.1 - 2.1 8.1 7.4 8.6 6.1 5.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) APG6 PF04111.7 EIE85535.1 - 3.2 6.7 12.2 5.4 5.9 8.5 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 XhlA PF10779.4 EIE85535.1 - 3.7 7.5 9.9 2.8 7.8 0.3 2.6 2 1 0 2 2 2 0 Haemolysin XhlA ACCA PF03255.9 EIE85535.1 - 4.3 6.8 6.7 1.5 8.3 0.9 2.2 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Lectin_N PF03954.9 EIE85535.1 - 4.8 6.5 8.1 3.4 7.0 3.0 2.2 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain DUF2951 PF11166.3 EIE85535.1 - 5.1 7.0 8.9 2.5 8.0 3.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2951) Fib_alpha PF08702.5 EIE85535.1 - 5.3 7.1 8.3 10 6.2 5.8 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Syntaxin-6_N PF09177.6 EIE85535.1 - 6.9 7.1 9.7 27 5.2 0.5 2.5 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF16 PF01519.11 EIE85535.1 - 7.6 6.8 12.0 19 5.5 8.3 1.7 1 1 0 1 1 1 0 Protein of unknown function DUF16 Prefoldin_2 PF01920.15 EIE85535.1 - 7.9 6.3 17.2 4.7 7.0 2.6 3.1 1 1 1 2 2 2 0 Prefoldin subunit FMN_dh PF01070.13 EIE85536.1 - 3.6 6.3 5.2 4.5 6.0 3.6 1.1 1 0 0 1 1 1 0 FMN-dependent dehydrogenase Hid1 PF12722.2 EIE85536.1 - 4.3 4.9 13.8 4.3 4.9 9.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SPRY PF00622.23 EIE85537.1 - 2e-15 56.9 0.1 1.5e-12 47.6 0.1 2.6 2 0 0 2 2 2 2 SPRY domain Macoilin PF09726.4 EIE85537.1 - 1.7 6.7 6.4 2.4 6.3 4.4 1.2 1 0 0 1 1 1 0 Transmembrane protein Ribosomal_L21p PF00829.16 EIE85538.1 - 9e-08 32.1 0.5 4.7e-07 29.8 0.0 2.3 3 0 0 3 3 3 1 Ribosomal prokaryotic L21 protein Preseq_ALAS PF09029.5 EIE85538.1 - 0.17 11.9 0.6 0.34 10.9 0.1 1.8 2 0 0 2 2 2 0 5-aminolevulinate synthase presequence Pkinase PF00069.20 EIE85539.1 - 2.1e-60 204.0 0.0 2.3e-60 203.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE85539.1 - 9.6e-32 110.0 0.0 1.2e-31 109.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIE85539.1 - 1.2e-07 31.7 0.0 3.3e-05 23.7 0.0 2.4 2 1 1 3 3 3 2 Phosphotransferase enzyme family RIO1 PF01163.17 EIE85539.1 - 8e-05 22.0 0.1 0.00013 21.4 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 EIE85539.1 - 8.2e-05 21.7 0.0 0.00013 21.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EIE85539.1 - 0.00013 21.0 0.0 0.00018 20.5 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.15 EIE85539.1 - 0.0028 17.2 0.0 0.0047 16.5 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Act-Frag_cataly PF09192.5 EIE85539.1 - 0.048 12.6 0.1 0.076 11.9 0.1 1.2 1 0 0 1 1 1 0 Actin-fragmin kinase, catalytic YrbL-PhoP_reg PF10707.4 EIE85539.1 - 0.077 12.3 0.1 0.19 11.0 0.0 1.6 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL CH PF00307.26 EIE85539.1 - 0.097 12.7 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Calponin homology (CH) domain TLD PF07534.11 EIE85540.1 - 1.2e-26 93.3 1.1 2.1e-26 92.5 0.7 1.4 1 0 0 1 1 1 1 TLD Glyco_hydro_18 PF00704.23 EIE85542.1 - 2.7e-81 273.7 3.0 3.1e-81 273.4 2.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 SNF2_N PF00176.18 EIE85543.1 - 1.6e-11 43.5 0.1 2.4e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Protocadherin PF08374.6 EIE85543.1 - 0.55 9.8 4.4 0.94 9.0 3.1 1.3 1 0 0 1 1 1 0 Protocadherin Pox_Ag35 PF03286.9 EIE85543.1 - 2.2 7.7 13.6 0.3 10.6 5.0 2.0 2 0 0 2 2 2 0 Pox virus Ag35 surface protein PGA2 PF07543.7 EIE85543.1 - 4.7 7.0 13.7 1.4 8.6 3.4 2.3 2 0 0 2 2 2 0 Protein trafficking PGA2 PBP1_TM PF14812.1 EIE85543.1 - 5.5 7.3 17.1 0.3 11.4 5.3 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal zf-RVT PF13966.1 EIE85544.1 - 1.2e-05 25.4 2.1 1.8e-05 24.9 0.7 1.9 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase zf-CCHC PF00098.18 EIE85547.1 - 0.13 12.2 7.7 0.23 11.4 0.3 2.8 2 1 0 2 2 2 0 Zinc knuckle DUF566 PF04484.7 EIE85547.1 - 0.75 9.2 7.1 1.1 8.6 4.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) RdRP PF05183.7 EIE85548.1 - 5e-95 319.3 0.8 1.8e-93 314.1 0.6 2.2 1 1 0 1 1 1 1 RNA dependent RNA polymerase RRM_1 PF00076.17 EIE85548.1 - 2e-05 24.1 0.0 0.00021 20.8 0.0 2.7 4 0 0 4 4 4 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE85548.1 - 0.038 13.8 0.0 0.15 11.9 0.0 2.1 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE85548.1 - 0.039 13.9 0.0 0.12 12.3 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CAP PF00188.21 EIE85549.1 - 1e-24 87.4 6.7 1.2e-24 87.1 4.7 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family DDE_3 PF13358.1 EIE85551.1 - 1.6e-16 60.3 0.0 1.7e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE85551.1 - 0.016 15.2 0.0 0.019 15.0 0.0 1.2 1 0 0 1 1 1 0 Integrase core domain PRC PF05239.11 EIE85552.1 - 0.085 12.7 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 PRC-barrel domain DDE_1 PF03184.14 EIE85554.1 - 4.4e-06 25.9 0.0 9.1e-06 24.9 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EIE85554.1 - 5.2e-06 26.1 0.0 9.3e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DUF3126 PF11324.3 EIE85554.1 - 0.024 14.3 0.0 0.051 13.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3126) Topoisom_I_N PF02919.10 EIE85555.1 - 1.9e-98 328.0 3.0 1.9e-98 328.0 2.1 3.9 4 0 0 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 EIE85555.1 - 2.2e-86 288.7 6.1 6.3e-86 287.2 4.2 1.8 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 EIE85555.1 - 5.8e-32 109.1 1.6 2.2e-31 107.3 1.1 2.1 1 0 0 1 1 1 1 C-terminal topoisomerase domain Phosducin PF02114.11 EIE85556.1 - 9.3e-22 77.0 0.5 2.3e-17 62.5 0.0 2.2 1 1 1 2 2 2 2 Phosducin Rep_fac-A_3 PF08661.6 EIE85557.1 - 3.5e-17 62.2 0.0 4e-17 62.0 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 HA2 PF04408.18 EIE85559.1 - 5.4e-31 106.6 0.3 1.5e-30 105.2 0.2 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EIE85559.1 - 8.4e-30 102.9 0.0 2.7e-29 101.2 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EIE85559.1 - 2.7e-11 43.1 0.0 6.5e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EIE85559.1 - 3.6e-06 26.5 0.0 8e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EIE85559.1 - 0.021 14.9 0.0 0.093 12.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain Flavi_DEAD PF07652.9 EIE85559.1 - 0.044 13.5 0.0 0.099 12.4 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain DUF866 PF05907.8 EIE85560.1 - 3.2e-43 147.0 0.9 1.1e-37 128.9 0.4 2.0 1 1 1 2 2 2 2 Eukaryotic protein of unknown function (DUF866) BPL_N PF09825.4 EIE85561.1 - 4.5e-78 262.5 0.0 5.5e-78 262.3 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.14 EIE85561.1 - 7.7e-07 29.1 0.0 2.3e-06 27.6 0.0 1.7 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.12 EIE85561.1 - 0.00034 20.2 0.0 0.00096 18.7 0.0 1.8 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain Peptidase_S51 PF03575.12 EIE85561.1 - 0.00085 19.0 0.0 0.0016 18.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase family S51 Methyltransf_8 PF05148.10 EIE85561.1 - 0.14 11.7 0.0 0.34 10.4 0.0 1.7 1 0 0 1 1 1 0 Hypothetical methyltransferase GATase_3 PF07685.9 EIE85561.1 - 0.15 11.6 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain DUF4539 PF15072.1 EIE85562.1 - 0.00058 19.4 0.1 0.00087 18.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4539) Cyclin PF08613.6 EIE85563.1 - 0.00028 21.3 0.6 0.00081 19.8 0.0 2.0 2 1 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 EIE85563.1 - 0.0091 15.5 0.0 0.021 14.3 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF2511 PF10709.4 EIE85563.1 - 0.011 16.0 0.3 0.038 14.3 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2511) RRM_1 PF00076.17 EIE85564.1 - 1.1e-29 101.8 0.3 9.8e-20 69.9 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE85564.1 - 1.4e-18 66.4 0.0 1.4e-08 34.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE85564.1 - 2.6e-18 65.7 0.2 3.3e-12 46.1 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 EIE85564.1 - 5.6e-09 35.5 1.3 1.6e-07 30.8 0.1 2.4 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain Limkain-b1 PF11608.3 EIE85564.1 - 0.0092 15.7 0.1 1.3 8.7 0.0 2.4 2 0 0 2 2 2 1 Limkain b1 Nup35_RRM_2 PF14605.1 EIE85564.1 - 0.048 13.4 0.0 3.7 7.3 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Mito_fiss_reg PF05308.6 EIE85564.1 - 0.18 11.1 13.5 0.36 10.1 0.7 2.4 1 1 1 2 2 2 0 Mitochondrial fission regulator Acyltransferase PF01553.16 EIE85565.1 - 7.3e-09 35.1 0.0 1.4e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase DUF1451 PF07295.6 EIE85565.1 - 0.061 13.0 3.4 4.3 7.0 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1451) Borrelia_lipo_1 PF05714.6 EIE85565.1 - 0.21 10.6 5.2 0.26 10.3 1.7 2.3 2 0 0 2 2 2 0 Borrelia burgdorferi virulent strain associated lipoprotein Dict-STAT-coil PF09267.5 EIE85565.1 - 0.36 11.0 5.2 5.7 7.1 0.1 3.4 3 0 0 3 3 3 0 Dictyostelium STAT, coiled coil OrfB_Zn_ribbon PF07282.6 EIE85566.1 - 0.084 12.5 0.2 0.5 10.0 0.0 2.3 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Aconitase PF00330.15 EIE85567.1 - 1.9e-178 593.7 0.2 6e-178 592.0 0.1 1.8 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EIE85567.1 - 5.3e-44 149.4 0.0 9.4e-44 148.6 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Pkinase PF00069.20 EIE85568.1 - 3e-56 190.4 0.0 4.6e-56 189.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE85568.1 - 7.8e-20 71.0 0.0 1.1e-19 70.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIE85568.1 - 8e-06 25.7 0.0 1.6e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EIE85568.1 - 0.0026 17.3 2.7 0.12 11.8 0.0 2.4 2 0 0 2 2 2 2 Choline/ethanolamine kinase Kinase-like PF14531.1 EIE85568.1 - 0.034 13.0 0.0 0.054 12.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 EIE85568.1 - 0.15 11.1 0.0 0.28 10.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RGS PF00615.14 EIE85569.1 - 5e-08 33.0 0.2 1.7e-07 31.3 0.1 1.9 2 0 0 2 2 2 1 Regulator of G protein signaling domain PP2C PF00481.16 EIE85572.1 - 9.5e-22 77.6 0.0 6.4e-20 71.6 0.0 2.2 1 1 0 1 1 1 1 Protein phosphatase 2C Sed5p PF11416.3 EIE85573.1 - 0.19 11.2 0.8 0.48 9.9 0.0 2.0 2 0 0 2 2 2 0 Integral membrane protein Sed5p GTP_EFTU_D3 PF03143.12 EIE85574.1 - 1.5e-11 44.2 0.0 1.6e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain PHD PF00628.24 EIE85575.1 - 7.8e-09 35.1 9.4 7.8e-09 35.1 6.5 2.1 2 1 0 2 2 2 1 PHD-finger zf-CW PF07496.10 EIE85575.1 - 0.057 13.1 0.3 0.057 13.1 0.2 3.8 4 0 0 4 4 4 0 CW-type Zinc Finger PHD_2 PF13831.1 EIE85575.1 - 0.93 8.8 6.1 1.3 8.3 3.3 2.0 2 0 0 2 2 2 0 PHD-finger zf-HC5HC2H PF13771.1 EIE85575.1 - 6.9 6.8 9.3 1.5 8.9 3.9 1.8 2 0 0 2 2 2 0 PHD-like zinc-binding domain DEAD PF00270.24 EIE85576.1 - 3.8e-47 159.9 0.0 7.6e-46 155.6 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIE85576.1 - 1.3e-26 92.2 0.0 5.1e-26 90.3 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EIE85576.1 - 8.7e-05 21.4 0.3 0.00031 19.6 0.0 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain DUF1253 PF06862.7 EIE85576.1 - 0.0046 15.4 0.1 0.0046 15.4 0.0 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF1253) CMS1 PF14617.1 EIE85576.1 - 0.022 13.8 17.7 0.12 11.3 0.0 3.3 4 0 0 4 4 4 0 U3-containing 90S pre-ribosomal complex subunit CDC73 PF05179.9 EIE85576.1 - 1.9 7.7 11.6 12 5.1 6.5 2.2 2 0 0 2 2 2 0 RNA pol II accessory factor, Cdc73 family DUF2009 PF09418.5 EIE85577.1 - 2e-193 643.3 0.1 2.4e-193 643.0 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) ABC_membrane PF00664.18 EIE85578.1 - 4.6e-52 177.1 35.1 3.4e-28 98.8 5.0 3.1 3 1 0 3 3 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EIE85578.1 - 1.2e-48 164.8 0.0 1e-27 97.1 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EIE85578.1 - 1.5e-09 37.4 5.3 0.00076 18.7 0.1 4.4 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EIE85578.1 - 4.9e-08 33.2 8.5 0.0059 16.6 0.0 5.8 4 2 0 4 4 4 2 AAA domain AAA_29 PF13555.1 EIE85578.1 - 9.9e-07 28.2 0.5 0.026 14.0 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 EIE85578.1 - 2.1e-06 27.3 0.2 0.004 16.6 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family T2SE PF00437.15 EIE85578.1 - 1.7e-05 23.9 0.0 0.047 12.5 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_17 PF13207.1 EIE85578.1 - 4e-05 24.4 0.1 0.4 11.4 0.0 3.6 3 0 0 3 3 2 2 AAA domain Miro PF08477.8 EIE85578.1 - 5.5e-05 23.6 0.2 0.029 14.8 0.0 2.9 2 0 0 2 2 2 1 Miro-like protein AAA_25 PF13481.1 EIE85578.1 - 0.00011 21.6 0.1 0.31 10.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EIE85578.1 - 0.00018 21.5 0.1 0.96 9.3 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain DUF87 PF01935.12 EIE85578.1 - 0.00024 20.9 3.2 0.22 11.3 0.4 2.7 2 0 0 2 2 2 2 Domain of unknown function DUF87 AAA_23 PF13476.1 EIE85578.1 - 0.00027 21.3 6.7 0.12 12.6 0.0 4.1 4 0 0 4 4 4 2 AAA domain MMR_HSR1 PF01926.18 EIE85578.1 - 0.00046 20.1 0.3 1.5 8.7 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.1 EIE85578.1 - 0.00081 19.5 0.9 4.6 7.3 0.3 3.9 2 1 0 2 2 2 1 AAA domain ATP_bind_1 PF03029.12 EIE85578.1 - 0.001 18.6 1.3 0.83 9.1 0.0 3.4 3 0 0 3 3 3 1 Conserved hypothetical ATP binding protein ResIII PF04851.10 EIE85578.1 - 0.0011 18.8 0.0 0.064 13.0 0.0 3.5 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.4 EIE85578.1 - 0.0018 16.9 0.2 0.61 8.6 0.0 2.4 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain AAA_10 PF12846.2 EIE85578.1 - 0.0039 16.6 0.4 2.7 7.3 0.0 2.8 2 1 0 2 2 2 2 AAA-like domain AAA_18 PF13238.1 EIE85578.1 - 0.0048 17.2 0.1 2 8.7 0.1 3.3 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EIE85578.1 - 0.0066 16.1 1.0 0.76 9.4 0.1 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 EIE85578.1 - 0.0089 15.8 2.1 0.031 14.1 0.1 2.6 2 0 0 2 2 2 1 Dynamin family DUF258 PF03193.11 EIE85578.1 - 0.03 13.4 0.2 0.68 9.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 EIE85578.1 - 0.031 13.3 0.0 2.2 7.3 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.1 EIE85578.1 - 0.061 13.1 0.1 2.2 8.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EIE85578.1 - 0.47 10.0 0.6 32 4.0 0.0 2.9 3 0 0 3 3 3 0 AAA domain Hydrolase PF00702.21 EIE85579.1 - 7.6e-30 104.9 0.0 1.1e-29 104.4 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EIE85579.1 - 1.6e-16 61.0 0.0 4e-16 59.7 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EIE85579.1 - 0.0015 18.2 0.2 0.0032 17.0 0.0 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase NB PF04159.8 EIE85579.1 - 0.017 14.8 0.1 0.041 13.6 0.0 1.6 1 0 0 1 1 1 0 NB glycoprotein E1-E2_ATPase PF00122.15 EIE85579.1 - 0.029 13.4 0.3 0.029 13.4 0.2 2.7 2 1 0 2 2 2 0 E1-E2 ATPase E1-E2_ATPase PF00122.15 EIE85580.1 - 2.3e-17 62.7 0.0 3.1e-17 62.4 0.0 1.1 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_N PF00690.21 EIE85580.1 - 1.6e-08 33.9 0.0 2.6e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Mcp5_PH PF12814.2 EIE85581.1 - 3.2e-33 114.2 0.1 3.2e-33 114.2 0.1 3.5 3 0 0 3 3 3 1 Meiotic cell cortex C-terminal pleckstrin homology FATC PF02260.15 EIE85581.1 - 0.052 12.9 20.0 4 6.9 0.0 10.0 12 0 0 12 12 12 0 FATC domain His_biosynth PF00977.16 EIE85583.1 - 1.5e-49 168.3 0.1 1e-48 165.6 0.1 2.3 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.23 EIE85583.1 - 1e-24 87.0 0.0 1.9e-24 86.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.9 EIE85583.1 - 1.6e-09 37.5 0.0 3.9e-09 36.2 0.0 1.7 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.14 EIE85583.1 - 3.5e-09 36.5 0.0 8.4e-08 32.0 0.0 2.4 1 1 0 1 1 1 1 SNO glutamine amidotransferase family BPL_N PF09825.4 EIE85583.1 - 0.00011 21.1 0.1 0.0016 17.2 0.0 2.1 2 0 0 2 2 2 1 Biotin-protein ligase, N terminal Peptidase_C26 PF07722.8 EIE85583.1 - 0.031 13.7 0.1 0.14 11.5 0.1 2.1 1 1 0 1 1 1 0 Peptidase C26 Dus PF01207.12 EIE85583.1 - 0.065 12.0 0.0 0.13 11.0 0.0 1.4 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) DUF2370 PF10176.4 EIE85584.1 - 1.1e-43 149.2 4.1 2.4e-32 112.1 0.1 2.6 3 0 0 3 3 3 2 Protein of unknown function (DUF2370) USP7_C2 PF14533.1 EIE85584.1 - 0.027 13.9 0.2 0.042 13.2 0.2 1.2 1 0 0 1 1 1 0 Ubiquitin-specific protease C-terminal Ion_trans_2 PF07885.11 EIE85584.1 - 0.25 11.0 1.5 1.2 8.8 0.1 2.1 2 0 0 2 2 2 0 Ion channel HEAT_2 PF13646.1 EIE85586.1 - 7.6e-50 167.1 10.6 4.2e-17 62.2 0.2 4.1 1 1 4 5 5 5 5 HEAT repeats HEAT_PBS PF03130.11 EIE85586.1 - 1.2e-30 102.7 0.4 5.6e-05 23.2 0.0 6.6 6 0 0 6 6 6 6 PBS lyase HEAT-like repeat HEAT PF02985.17 EIE85586.1 - 2.6e-15 55.0 1.3 0.031 14.3 0.0 7.1 7 0 0 7 7 7 4 HEAT repeat HEAT_EZ PF13513.1 EIE85586.1 - 4.5e-14 52.4 2.3 0.00023 21.5 0.0 6.1 4 2 3 7 7 7 4 HEAT-like repeat Arm PF00514.18 EIE85586.1 - 0.0035 17.1 1.2 4.8 7.1 0.0 4.1 4 1 1 5 5 5 1 Armadillo/beta-catenin-like repeat GIT_SHD PF08518.6 EIE85587.1 - 2.3e-24 84.3 3.3 1.8e-13 49.6 0.3 2.6 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT DUF4314 PF14192.1 EIE85587.1 - 0.038 14.2 0.4 6 7.2 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4314) DUF4515 PF14988.1 EIE85587.1 - 0.059 13.0 24.5 0.17 11.5 17.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) Fib_alpha PF08702.5 EIE85587.1 - 0.091 12.8 22.0 0.28 11.3 4.9 3.6 3 1 0 3 3 3 0 Fibrinogen alpha/beta chain family HTH_AsnC-type PF13404.1 EIE85587.1 - 0.11 12.0 0.4 0.46 10.0 0.2 2.2 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Costars PF14705.1 EIE85587.1 - 0.19 11.7 3.1 2.8 7.9 0.0 3.1 3 0 0 3 3 3 0 Costars LMBR1 PF04791.11 EIE85587.1 - 0.23 10.0 4.2 0.33 9.4 2.9 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein V_ATPase_I PF01496.14 EIE85587.1 - 1.2 6.9 6.9 2.1 6.0 4.8 1.5 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 EIE85587.1 - 1.3 8.5 13.2 4.2 6.9 9.1 1.9 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 EIE85587.1 - 1.6 7.7 20.1 0.54 9.2 11.8 1.7 2 0 0 2 2 2 0 Autophagy protein Apg6 La PF05383.12 EIE85588.1 - 1.5e-20 72.6 0.9 3.2e-20 71.6 0.1 2.0 2 0 0 2 2 2 1 La domain Fanconi_A PF03511.9 EIE85589.1 - 0.0028 17.3 1.4 0.0045 16.7 1.0 1.6 1 1 0 1 1 1 1 Fanconi anaemia group A protein MARVEL PF01284.18 EIE85589.1 - 0.032 14.0 5.5 0.038 13.8 3.8 1.1 1 0 0 1 1 1 0 Membrane-associating domain Tetraspannin PF00335.15 EIE85589.1 - 0.051 12.8 2.4 0.055 12.7 1.7 1.0 1 0 0 1 1 1 0 Tetraspanin family DUF2207 PF09972.4 EIE85589.1 - 0.18 10.3 4.4 0.19 10.2 3.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) NfeD PF01957.13 EIE85589.1 - 0.83 9.7 4.2 0.92 9.6 2.9 1.1 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding DUF962 PF06127.6 EIE85589.1 - 4.3 7.2 7.8 1.4 8.8 3.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF962) PRA1 PF03208.14 EIE85589.1 - 5 6.4 7.9 6 6.1 5.5 1.1 1 0 0 1 1 1 0 PRA1 family protein ETF PF01012.16 EIE85590.1 - 2.3e-42 144.4 1.0 3.4e-42 143.9 0.7 1.2 1 0 0 1 1 1 1 Electron transfer flavoprotein domain WD40 PF00400.27 EIE85590.1 - 2.1e-11 43.2 10.5 0.00032 20.4 0.0 5.5 6 0 0 6 6 6 3 WD domain, G-beta repeat RRM_1 PF00076.17 EIE85591.1 - 4.2e-69 228.1 0.7 9.3e-19 66.8 0.0 4.1 3 1 1 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE85591.1 - 4.9e-50 167.3 0.1 2.1e-15 56.4 0.0 4.1 3 1 1 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE85591.1 - 1.3e-35 120.9 0.1 1.1e-08 34.7 0.0 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EIE85591.1 - 9.1e-05 22.2 0.1 0.17 11.7 0.0 3.7 4 0 0 4 4 4 1 RNA binding motif Limkain-b1 PF11608.3 EIE85591.1 - 0.00085 19.0 0.1 3.6 7.3 0.0 3.6 4 0 0 4 4 4 1 Limkain b1 OB_RNB PF08206.6 EIE85591.1 - 0.0036 16.7 1.9 6.5 6.3 0.0 3.4 3 0 0 3 3 3 2 Ribonuclease B OB domain Aminotran_1_2 PF00155.16 EIE85592.1 - 1.4e-39 136.0 0.0 2.7e-39 135.1 0.0 1.4 2 0 0 2 2 2 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EIE85592.1 - 0.011 14.8 0.0 0.02 14.0 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase MFS_1 PF07690.11 EIE85594.1 - 3.4e-44 150.9 40.8 3.4e-44 150.9 28.3 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIE85594.1 - 2.2e-14 52.9 9.7 2.2e-14 52.9 6.7 3.4 2 1 2 4 4 4 2 Sugar (and other) transporter YrhC PF14143.1 EIE85594.1 - 0.47 10.4 3.2 2.1 8.3 0.0 3.1 3 0 0 3 3 3 0 YrhC-like protein GoLoco PF02188.12 EIE85595.1 - 5.2 6.5 15.9 0.032 13.5 3.3 3.3 4 0 0 4 4 4 0 GoLoco motif Mak16 PF04874.9 EIE85596.1 - 0.15 12.1 4.3 3 7.9 0.3 2.7 2 1 0 2 2 2 0 Mak16 protein C-terminal region Band_7_1 PF13421.1 EIE85596.1 - 0.15 11.5 3.1 0.07 12.6 0.6 1.5 2 0 0 2 2 2 0 SPFH domain-Band 7 family DDE_3 PF13358.1 EIE85597.1 - 3.5e-09 36.5 0.0 6.1e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease bZIP_2 PF07716.10 EIE85598.1 - 4.3e-10 39.2 5.3 1.2e-09 37.8 3.7 1.8 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 EIE85598.1 - 1.9e-06 27.7 4.7 1.9e-06 27.7 3.2 1.9 2 0 0 2 2 2 1 bZIP transcription factor SAC3_GANP PF03399.11 EIE85599.1 - 3.3e-26 92.1 0.6 3.3e-26 92.1 0.4 2.1 2 0 0 2 2 2 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Suf PF05843.9 EIE85599.1 - 0.9 9.2 11.6 1.9 8.1 8.1 1.6 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) RR_TM4-6 PF06459.7 EIE85599.1 - 1.2 8.9 8.3 2 8.2 5.8 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Prok-RING_1 PF14446.1 EIE85601.1 - 0.0011 18.6 0.4 0.0011 18.6 0.3 1.5 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 ADK_lid PF05191.9 EIE85601.1 - 0.0044 16.6 3.7 0.038 13.6 0.1 3.0 3 0 0 3 3 3 1 Adenylate kinase, active site lid Vps39_2 PF10367.4 EIE85601.1 - 0.0092 16.1 0.2 0.013 15.6 0.2 1.2 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 LIM PF00412.17 EIE85601.1 - 1.4 9.0 4.8 0.21 11.6 0.6 1.6 2 0 0 2 2 2 0 LIM domain zf-GRF PF06839.7 EIE85601.1 - 6.4 6.7 6.6 7.3 6.6 0.5 2.1 2 0 0 2 2 2 0 GRF zinc finger zf-RING_5 PF14634.1 EIE85602.1 - 0.019 14.7 8.3 0.056 13.1 5.7 1.9 1 1 0 1 1 1 0 zinc-RING finger domain Rubredoxin PF00301.15 EIE85602.1 - 1.9 8.4 6.2 6.6 6.6 2.6 2.5 2 0 0 2 2 2 0 Rubredoxin Homeobox PF00046.24 EIE85603.1 - 2.1e-17 62.4 1.2 3.8e-17 61.6 0.8 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EIE85603.1 - 0.0016 18.1 3.6 0.0022 17.6 0.3 2.4 2 0 0 2 2 2 1 Homeobox KN domain Adaptin_N PF01602.15 EIE85604.1 - 3.4e-142 474.4 12.9 3.7e-141 471.0 7.3 2.0 1 1 1 2 2 2 2 Adaptin N terminal region Cnd1 PF12717.2 EIE85604.1 - 9.7e-28 97.2 5.9 1.7e-26 93.1 0.5 3.6 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EIE85604.1 - 6.7e-18 64.7 0.8 6.7e-09 35.9 0.0 5.7 1 1 4 5 5 5 3 HEAT repeats HEAT PF02985.17 EIE85604.1 - 5.5e-08 32.2 6.0 0.0029 17.5 0.0 5.4 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.1 EIE85604.1 - 3.1e-06 27.4 0.4 0.066 13.7 0.0 5.6 5 2 1 6 6 6 1 HEAT-like repeat CLASP_N PF12348.3 EIE85604.1 - 9.1e-05 21.9 0.1 0.013 14.8 0.0 2.8 2 0 0 2 2 2 1 CLASP N terminal Arm PF00514.18 EIE85604.1 - 0.0054 16.5 2.3 2.8 7.9 0.0 4.5 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.4 EIE85604.1 - 0.026 14.2 0.1 6.3 6.5 0.0 3.2 3 0 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain DUF1548 PF07579.6 EIE85604.1 - 0.088 12.9 0.3 1.9 8.5 0.0 3.2 2 2 2 4 4 4 0 Domain of Unknown Function (DUF1548) RHD3 PF05879.7 EIE85605.1 - 2.5e-245 815.9 12.3 6.3e-211 702.1 5.6 2.1 1 1 1 2 2 2 2 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 EIE85605.1 - 7.9e-07 28.3 0.3 2e-06 27.0 0.2 1.6 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.18 EIE85605.1 - 6.1e-06 26.1 0.3 2e-05 24.4 0.0 2.0 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 EIE85605.1 - 9.6e-05 22.3 0.0 0.00024 21.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EIE85605.1 - 0.00022 21.6 0.3 0.00072 20.0 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein AAA_28 PF13521.1 EIE85605.1 - 0.0095 15.9 0.0 0.025 14.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain Cytochrom_C_2 PF01322.15 EIE85605.1 - 0.021 15.3 4.5 0.65 10.5 0.2 3.5 3 0 0 3 3 3 0 Cytochrome C' Ank_2 PF12796.2 EIE85607.1 - 3.2e-52 174.8 7.9 3.2e-17 62.6 0.2 3.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EIE85607.1 - 6.6e-37 123.5 13.7 6.6e-09 35.1 0.0 5.9 6 0 0 6 6 6 5 Ankyrin repeat zf-DHHC PF01529.15 EIE85607.1 - 8.3e-35 119.7 10.2 8.3e-35 119.7 7.1 2.4 3 0 0 3 3 3 1 DHHC palmitoyltransferase Ank_5 PF13857.1 EIE85607.1 - 5.5e-28 96.3 9.8 2.5e-07 30.7 0.1 5.3 2 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIE85607.1 - 2.8e-26 88.9 9.7 1.9e-05 24.4 0.0 6.1 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.1 EIE85607.1 - 2.1e-24 85.4 3.4 3.3e-08 33.8 0.1 4.9 3 2 1 4 4 4 4 Ankyrin repeats (many copies) PIN_4 PF13638.1 EIE85608.1 - 2.4e-13 50.3 0.1 3.4e-13 49.8 0.1 1.3 1 0 0 1 1 1 1 PIN domain Fmp27_SW PF10305.4 EIE85608.1 - 0.0096 16.3 1.1 0.17 12.3 0.1 2.3 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Homeobox PF00046.24 EIE85609.1 - 1.4e-19 69.4 2.0 2.8e-19 68.4 1.4 1.6 1 0 0 1 1 1 1 Homeobox domain PAT1 PF09770.4 EIE85609.1 - 8.1 4.5 29.7 11 4.0 20.6 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AAA PF00004.24 EIE85610.1 - 4.6e-42 143.3 0.0 8.8e-42 142.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EIE85610.1 - 3.5e-06 27.0 0.0 6.9e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EIE85610.1 - 6e-06 26.4 0.1 0.00073 19.6 0.1 2.4 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 EIE85610.1 - 1.7e-05 23.8 0.0 2.9e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 EIE85610.1 - 3.2e-05 23.6 0.4 0.00042 20.0 0.2 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EIE85610.1 - 0.00013 22.0 0.0 0.00076 19.5 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 EIE85610.1 - 0.00044 19.3 0.0 0.0008 18.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EIE85610.1 - 0.0011 18.8 0.0 0.0021 17.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 EIE85610.1 - 0.0029 17.2 0.0 0.0087 15.6 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EIE85610.1 - 0.0047 17.2 0.1 0.02 15.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EIE85610.1 - 0.005 17.6 0.7 0.0095 16.7 0.2 2.0 2 1 0 2 2 1 1 AAA domain AAA_19 PF13245.1 EIE85610.1 - 0.0064 16.2 0.4 0.014 15.1 0.2 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 EIE85610.1 - 0.0065 16.3 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 EIE85610.1 - 0.0073 15.4 0.7 0.18 10.9 0.1 2.7 2 1 1 3 3 3 1 KaiC IstB_IS21 PF01695.12 EIE85610.1 - 0.011 15.1 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Zeta_toxin PF06414.7 EIE85610.1 - 0.016 14.3 0.0 0.027 13.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin NB-ARC PF00931.17 EIE85610.1 - 0.016 14.0 0.0 0.054 12.3 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain NACHT PF05729.7 EIE85610.1 - 0.024 14.3 0.1 0.36 10.4 0.1 2.3 1 1 0 2 2 2 0 NACHT domain AAA_28 PF13521.1 EIE85610.1 - 0.026 14.4 1.8 0.063 13.2 0.0 2.4 3 0 0 3 3 2 0 AAA domain TIP49 PF06068.8 EIE85610.1 - 0.032 12.9 0.0 0.051 12.2 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus AAA_25 PF13481.1 EIE85610.1 - 0.045 13.1 0.9 1.7 7.9 0.2 2.6 1 1 1 2 2 2 0 AAA domain DUF2075 PF09848.4 EIE85610.1 - 0.062 12.2 0.0 0.085 11.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.17 EIE85610.1 - 0.082 13.0 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.16 EIE85610.1 - 0.098 11.8 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.13 EIE85610.1 - 0.1 12.0 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.1 EIE85610.1 - 0.11 12.0 0.2 0.31 10.5 0.2 1.7 1 0 0 1 1 1 0 AAA domain TatD_DNase PF01026.16 EIE85611.1 - 1.1e-46 159.1 0.1 1.3e-46 158.8 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase AAA_25 PF13481.1 EIE85612.1 - 4.6e-12 45.7 0.0 6.6e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EIE85612.1 - 0.00045 20.3 0.0 0.00099 19.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain RabGAP-TBC PF00566.13 EIE85613.1 - 1.8e-44 151.7 3.4 1.8e-44 151.7 2.4 2.3 2 0 0 2 2 2 1 Rab-GTPase-TBC domain SPAM PF02090.10 EIE85613.1 - 0.011 15.7 5.2 0.011 15.7 3.6 2.7 2 1 1 3 3 3 0 Salmonella surface presentation of antigen gene type M protein VPS11_C PF12451.3 EIE85613.1 - 0.061 13.1 0.9 0.19 11.6 0.0 2.3 2 0 0 2 2 2 0 Vacuolar protein sorting protein 11 C terminal DUF3573 PF12097.3 EIE85613.1 - 0.16 10.5 3.2 0.31 9.6 2.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) bZIP_1 PF00170.16 EIE85613.1 - 0.25 11.3 16.6 2.8 7.9 0.4 4.7 4 1 1 5 5 5 0 bZIP transcription factor BLOC1_2 PF10046.4 EIE85613.1 - 0.47 10.6 15.8 0.13 12.4 0.7 3.7 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Cep57_CLD_2 PF14197.1 EIE85613.1 - 1.1 9.2 24.6 0.36 10.8 9.6 4.5 3 1 1 4 4 4 0 Centrosome localisation domain of PPC89 DUF1664 PF07889.7 EIE85613.1 - 1.8 8.3 8.7 1.2 8.9 3.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Fez1 PF06818.10 EIE85613.1 - 3 7.8 20.8 0.17 11.8 9.5 2.2 2 0 0 2 2 2 0 Fez1 DUF948 PF06103.6 EIE85613.1 - 6.8 6.6 7.3 28 4.6 0.3 2.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF2781 PF10914.3 EIE85614.1 - 6.8e-36 123.3 14.9 1.3e-35 122.3 10.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) Prefoldin PF02996.12 EIE85614.1 - 3.4e-12 46.0 0.1 4.5e-12 45.6 0.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit PQ-loop PF04193.9 EIE85615.1 - 8e-14 50.9 1.6 8e-14 50.9 1.1 2.3 2 1 0 2 2 2 1 PQ loop repeat Sdh_cyt PF01127.17 EIE85615.1 - 0.18 11.6 5.2 0.28 11.0 0.2 2.4 2 0 0 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit MNHE PF01899.11 EIE85615.1 - 2 8.0 7.6 1.3 8.6 3.5 1.8 1 1 1 2 2 2 0 Na+/H+ ion antiporter subunit RDD PF06271.7 EIE85615.1 - 8 6.3 11.6 4.1 7.3 6.4 1.6 2 0 0 2 2 2 0 RDD family Hexokinase_2 PF03727.11 EIE85616.1 - 1.1e-58 198.3 0.0 1.5e-58 197.8 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EIE85616.1 - 2.2e-42 144.7 0.0 3.2e-42 144.1 0.0 1.2 1 0 0 1 1 1 1 Hexokinase CUE PF02845.11 EIE85617.1 - 0.00031 20.1 0.1 0.0026 17.2 0.0 2.3 2 0 0 2 2 2 1 CUE domain DUF3391 PF11871.3 EIE85617.1 - 1.1 9.4 4.6 0.84 9.8 0.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3391) DUF3897 PF13036.1 EIE85618.1 - 0.0085 15.7 0.9 3 7.4 0.4 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3897) EnY2 PF10163.4 EIE85618.1 - 0.039 13.8 0.2 0.039 13.8 0.1 2.0 2 0 0 2 2 2 0 Transcription factor e(y)2 YjcQ PF09639.5 EIE85618.1 - 0.061 13.4 0.1 0.19 11.8 0.0 2.0 2 0 0 2 2 2 0 YjcQ protein IncA PF04156.9 EIE85618.1 - 0.58 9.7 19.0 1.6 8.3 2.7 2.3 1 1 1 2 2 2 0 IncA protein FadA PF09403.5 EIE85618.1 - 2.2 8.3 10.7 0.82 9.6 0.2 3.0 1 1 2 3 3 3 0 Adhesion protein FadA HALZ PF02183.13 EIE85618.1 - 4.1 7.2 10.9 0.26 11.0 0.2 3.4 3 0 0 3 3 3 0 Homeobox associated leucine zipper Microtub_assoc PF07989.6 EIE85618.1 - 5.8 6.8 9.1 0.25 11.1 0.5 2.8 3 1 0 3 3 3 0 Microtubule associated DUF904 PF06005.7 EIE85618.1 - 9.8 6.5 15.9 3.5 7.9 1.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF904) HOOK PF05622.7 EIE85619.1 - 2.3e-23 81.9 2.5 2.6e-23 81.7 1.7 1.1 1 0 0 1 1 1 1 HOOK protein RB_A PF01858.12 EIE85619.1 - 0.0057 16.3 0.8 0.0084 15.7 0.6 1.3 1 0 0 1 1 1 1 Retinoblastoma-associated protein A domain MCM_N PF14551.1 EIE85619.1 - 0.012 16.0 1.0 0.07 13.6 0.2 2.0 1 1 0 2 2 2 0 MCM N-terminal domain DUF4427 PF14468.1 EIE85619.1 - 0.051 13.3 0.1 0.14 11.8 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4427) Got1 PF04178.7 EIE85620.1 - 9.8e-20 70.8 10.8 1.1e-19 70.6 7.5 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family DUF1109 PF06532.6 EIE85620.1 - 0.0029 17.0 1.6 0.0034 16.8 1.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1109) 2-Hacid_dh_C PF02826.14 EIE85621.1 - 3e-57 192.6 0.0 4.5e-57 192.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EIE85621.1 - 1.2e-31 108.9 0.0 1.5e-31 108.6 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EIE85621.1 - 0.0038 17.0 0.0 0.0082 15.9 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 EIE85621.1 - 0.011 15.5 0.1 0.033 14.0 0.0 1.8 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.7 EIE85621.1 - 0.022 14.1 0.1 0.12 11.7 0.0 2.0 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 EIE85621.1 - 0.049 14.0 0.0 0.13 12.7 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF2325 PF10087.4 EIE85621.1 - 0.061 13.1 0.0 15 5.5 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2325) TrkA_N PF02254.13 EIE85621.1 - 0.067 13.1 0.3 0.88 9.5 0.0 2.7 2 1 1 3 3 3 0 TrkA-N domain ThiF PF00899.16 EIE85621.1 - 0.09 12.6 1.1 6.7 6.5 0.0 3.3 3 1 0 3 3 3 0 ThiF family NAD_binding_7 PF13241.1 EIE85621.1 - 0.13 12.5 0.1 0.89 9.8 0.0 2.2 2 1 1 3 3 3 0 Putative NAD(P)-binding Pkinase PF00069.20 EIE85622.1 - 5.7e-54 182.9 0.6 9.5e-49 165.8 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIE85622.1 - 2.7e-21 75.8 0.2 7.7e-20 71.0 0.0 2.1 1 1 1 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE85622.1 - 2.1e-07 30.2 0.0 3.4e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 EIE85622.1 - 0.0001 21.7 0.1 0.00019 20.8 0.1 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.9 EIE85622.1 - 0.00062 18.8 0.5 0.0011 18.1 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIE85622.1 - 0.0021 17.8 0.0 0.0033 17.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EIE85622.1 - 0.01 15.2 0.3 0.022 14.0 0.2 1.6 1 0 0 1 1 1 1 RIO1 family Clathrin_lg_ch PF01086.12 EIE85623.1 - 0.083 12.7 1.4 0.1 12.4 1.0 1.1 1 0 0 1 1 1 0 Clathrin light chain Cyclin PF08613.6 EIE85625.1 - 2.1e-16 60.6 1.4 3.3e-16 60.0 0.4 1.7 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 EIE85625.1 - 4.5e-07 29.4 0.3 1.5e-06 27.7 0.2 1.9 1 0 0 1 1 1 1 Cyclin, N-terminal domain CBF PF03914.12 EIE85625.1 - 0.04 13.3 0.2 0.073 12.5 0.1 1.7 1 1 0 1 1 1 0 CBF/Mak21 family APG6 PF04111.7 EIE85627.1 - 0.93 8.4 8.6 1.1 8.2 5.9 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 AATF-Che1 PF13339.1 EIE85627.1 - 2.8 8.0 7.8 1.7 8.7 2.0 2.2 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor MFS_1 PF07690.11 EIE85628.1 - 6.2e-23 81.0 27.1 5.7e-15 54.8 11.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3169 PF11368.3 EIE85628.1 - 0.029 13.5 4.9 0.39 9.8 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3169) MFS_1 PF07690.11 EIE85629.1 - 2.7e-16 59.2 5.3 5e-16 58.3 3.7 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily adh_short PF00106.20 EIE85630.1 - 9.8e-27 93.8 2.2 1.3e-26 93.4 1.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIE85630.1 - 9.2e-13 48.5 0.2 1.1e-12 48.2 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIE85630.1 - 9e-11 41.7 2.2 6.6e-10 38.9 1.5 2.1 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 EIE85630.1 - 4.3e-05 22.3 0.4 8e-05 21.4 0.2 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 EIE85630.1 - 0.0025 16.8 0.1 0.0026 16.8 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Epimerase PF01370.16 EIE85630.1 - 0.0034 16.8 0.3 0.0052 16.2 0.2 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIE85630.1 - 0.0057 16.6 0.3 0.0096 15.9 0.2 1.5 1 0 0 1 1 1 1 NADH(P)-binding TrkA_N PF02254.13 EIE85630.1 - 0.016 15.1 0.2 0.032 14.2 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain F420_oxidored PF03807.12 EIE85630.1 - 0.034 14.5 0.2 0.1 13.0 0.1 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DEAD PF00270.24 EIE85631.1 - 5e-46 156.2 0.4 1e-45 155.2 0.2 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EIE85631.1 - 7.4e-23 79.8 0.7 1.4e-22 79.0 0.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EIE85631.1 - 1.3e-22 79.3 0.0 2.6e-22 78.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PhoH PF02562.11 EIE85631.1 - 0.013 14.7 0.1 0.026 13.7 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein ResIII PF04851.10 EIE85631.1 - 0.019 14.8 0.0 0.019 14.8 0.0 2.4 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 EIE85631.1 - 0.033 13.4 1.1 0.09 12.0 0.7 1.7 1 1 0 1 1 1 0 SecA DEAD-like domain AAA_19 PF13245.1 EIE85631.1 - 0.062 13.0 0.0 1.1 9.0 0.1 2.8 3 0 0 3 3 3 0 Part of AAA domain EF-hand_1 PF00036.27 EIE85632.1 - 3e-37 123.0 11.9 2.6e-09 35.7 0.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EIE85632.1 - 1.3e-33 114.9 4.4 1e-17 63.9 0.7 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EIE85632.1 - 1.9e-29 98.8 9.7 1.6e-08 33.6 0.2 4.5 3 1 1 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EIE85632.1 - 5.8e-29 98.1 11.7 1.4e-07 30.5 0.1 4.5 4 1 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 EIE85632.1 - 7.8e-29 99.0 13.0 1.2e-16 60.0 1.0 4.1 2 1 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.1 EIE85632.1 - 1.1e-12 47.6 0.0 2.6e-05 24.0 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 EIE85632.1 - 8.5e-09 35.0 4.1 0.00041 20.0 0.0 2.8 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EIE85632.1 - 2.2e-08 34.1 0.2 0.00061 19.8 0.1 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region TerB PF05099.8 EIE85632.1 - 0.0013 18.5 0.8 0.1 12.3 0.1 2.5 1 1 2 3 3 3 2 Tellurite resistance protein TerB Imm16 PF15565.1 EIE85632.1 - 0.012 15.5 3.6 0.14 12.0 1.2 2.4 1 1 1 2 2 2 0 Immunity protein 16 Caleosin PF05042.8 EIE85632.1 - 0.017 14.6 0.3 0.17 11.3 0.2 2.5 1 1 0 1 1 1 0 Caleosin related protein DUF1456 PF07308.8 EIE85632.1 - 0.045 13.8 0.2 1 9.4 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1456) DUF2623 PF11115.3 EIE85632.1 - 0.063 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2623) UPF0154 PF03672.8 EIE85632.1 - 0.071 12.7 0.0 0.4 10.3 0.0 2.2 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0154) DUF3164 PF11363.3 EIE85632.1 - 0.085 12.2 0.2 1.5 8.1 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3164) DUF533 PF04391.7 EIE85632.1 - 0.11 11.8 0.7 5.6 6.2 0.1 2.9 1 1 3 4 4 4 0 Protein of unknown function (DUF533) DUF3455 PF11937.3 EIE85633.1 - 2.9e-09 37.1 0.1 4.3e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) CAP_N PF01213.14 EIE85635.1 - 0.74 9.0 4.8 0.89 8.7 3.3 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Methyltransf_21 PF05050.7 EIE85636.1 - 5.8e-05 23.0 0.0 8.2e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase FkbM domain Na_Ca_ex PF01699.19 EIE85638.1 - 3.1e-36 124.0 25.3 6.3e-23 80.9 6.4 2.7 3 0 0 3 3 3 2 Sodium/calcium exchanger protein DUF4271 PF14093.1 EIE85638.1 - 0.0028 17.3 0.2 0.0028 17.3 0.1 3.0 1 1 1 3 3 3 1 Domain of unknown function (DUF4271) MtrF PF09472.5 EIE85638.1 - 0.86 8.8 3.7 0.38 10.0 0.2 2.3 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) DUF3112 PF11309.3 EIE85638.1 - 1.6 8.4 9.2 0.062 13.0 1.8 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3112) Glucan_synthase PF02364.10 EIE85639.1 - 0 1302.0 0.0 0 1301.5 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 EIE85639.1 - 1.6e-33 115.0 0.3 4.9e-33 113.5 0.2 1.9 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 NIF PF03031.13 EIE85640.1 - 8.9e-44 148.9 0.0 1.4e-43 148.3 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase TIP120 PF08623.5 EIE85640.1 - 0.1 12.1 0.5 0.2 11.2 0.4 1.4 1 0 0 1 1 1 0 TATA-binding protein interacting (TIP20) DUF4199 PF13858.1 EIE85640.1 - 3.1 7.6 4.5 6.3 6.6 3.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Fork_head PF00250.13 EIE85644.1 - 6.5e-35 119.0 0.4 1.7e-34 117.7 0.3 1.7 1 0 0 1 1 1 1 Fork head domain ChAPs PF09295.5 EIE85645.1 - 2.5e-136 454.5 4.9 6.5e-134 446.6 0.0 2.9 3 1 0 3 3 3 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.1 EIE85645.1 - 0.00062 20.0 0.8 0.0057 16.9 0.0 2.9 4 0 0 4 4 4 1 Tetratricopeptide repeat RNase_Zc3h12a_2 PF14626.1 EIE85645.1 - 0.11 12.3 0.0 26 4.7 0.0 3.2 3 0 0 3 3 3 0 Zc3h12a-like Ribonuclease NYN domain TPR_2 PF07719.12 EIE85645.1 - 0.14 12.1 5.5 2.2 8.4 0.5 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1387 PF07139.6 EIE85645.1 - 0.59 9.6 12.2 1 8.9 8.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Nop14 PF04147.7 EIE85645.1 - 0.7 7.7 13.4 0.99 7.2 9.3 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.5 EIE85645.1 - 1.8 7.5 18.1 2.6 7.0 12.6 1.1 1 0 0 1 1 1 0 BUD22 zf-CCHC PF00098.18 EIE85648.1 - 0.018 14.9 18.7 0.023 14.5 0.9 3.1 3 0 0 3 3 3 0 Zinc knuckle DnaJ_CXXCXGXG PF00684.14 EIE85648.1 - 0.41 10.7 7.5 5.4 7.1 0.1 2.5 2 0 0 2 2 2 0 DnaJ central domain RVT_1 PF00078.22 EIE85649.1 - 8.5e-34 116.7 0.1 1.7e-33 115.8 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.1 EIE85649.1 - 0.002 18.4 0.2 0.0062 16.8 0.1 1.9 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase DBR1 PF05011.8 EIE85650.1 - 1.7e-29 102.5 0.1 3e-29 101.7 0.1 1.4 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 EIE85650.1 - 1.3e-13 50.7 1.5 2e-13 50.1 1.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EIE85650.1 - 0.00043 20.1 0.0 0.00082 19.2 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain MPC PF03650.8 EIE85651.1 - 1.2e-42 144.6 0.2 1.3e-42 144.4 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) Gti1_Pac2 PF09729.4 EIE85652.1 - 1.3e-19 70.6 5.2 1.2e-11 44.8 0.3 2.3 1 1 1 2 2 2 2 Gti1/Pac2 family PEPCK_ATP PF01293.15 EIE85653.1 - 4.9e-222 737.4 0.0 5.9e-222 737.2 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_16 PF13191.1 EIE85653.1 - 0.038 13.9 0.0 0.1 12.5 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.1 EIE85653.1 - 0.11 11.8 0.1 0.35 10.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain DUF137 PF02006.11 EIE85654.1 - 0.011 15.1 0.0 0.026 13.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF137 TraG_N PF07916.6 EIE85654.1 - 0.18 10.2 0.5 0.28 9.5 0.4 1.3 1 0 0 1 1 1 0 TraG-like protein, N-terminal region PBP_dimer PF03717.10 EIE85654.1 - 0.32 11.0 6.2 0.091 12.8 1.8 1.9 2 0 0 2 2 2 0 Penicillin-binding Protein dimerisation domain DUF3474 PF11960.3 EIE85654.1 - 0.96 9.4 6.5 0.8 9.7 0.8 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3474) HPP PF04982.8 EIE85655.1 - 2.2e-35 121.0 4.4 3.2e-35 120.5 3.1 1.2 1 0 0 1 1 1 1 HPP family DUF983 PF06170.7 EIE85655.1 - 0.1 12.7 0.6 0.1 12.7 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF983) Na_K-ATPase PF00287.13 EIE85655.1 - 0.13 11.0 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 Sodium / potassium ATPase beta chain 5TM-5TMR_LYT PF07694.7 EIE85655.1 - 0.35 10.1 5.1 0.58 9.4 3.5 1.5 1 0 0 1 1 1 0 5TMR of 5TMR-LYT RRM_1 PF00076.17 EIE85660.1 - 9e-08 31.6 0.1 2.4e-07 30.2 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE85660.1 - 3e-07 30.3 0.0 6e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Tash_PEST PF07708.6 EIE85660.1 - 5.6 7.0 7.5 19 5.4 0.2 2.6 2 0 0 2 2 2 0 Tash protein PEST motif Rab5ip PF07019.7 EIE85661.1 - 0.14 12.3 0.0 0.14 12.2 0.0 1.0 1 0 0 1 1 1 0 Rab5-interacting protein (Rab5ip) Glyco_transf_20 PF00982.16 EIE85662.1 - 2.4e-08 32.9 0.0 9.2e-08 30.9 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase family 20 Peptidase_M24 PF00557.19 EIE85664.1 - 9.5e-40 136.3 0.1 7.4e-23 81.2 0.0 2.0 1 1 1 2 2 2 2 Metallopeptidase family M24 KH_1 PF00013.24 EIE85665.1 - 2.4e-11 43.0 0.0 4e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 KH domain AKAP7_NLS PF10469.4 EIE85665.1 - 3.8e-11 43.0 0.0 3.8e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain KH_3 PF13014.1 EIE85665.1 - 3.5e-09 36.1 0.1 6e-09 35.3 0.1 1.3 1 0 0 1 1 1 1 KH domain KH_2 PF07650.12 EIE85665.1 - 0.00019 20.9 0.6 0.00039 19.9 0.3 1.6 1 1 0 1 1 1 1 KH domain LigT_PEase PF02834.11 EIE85665.1 - 0.029 14.3 0.0 0.16 11.9 0.0 2.0 1 1 0 1 1 1 0 LigT like Phosphoesterase KH_5 PF13184.1 EIE85665.1 - 0.042 13.6 0.0 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 NusA-like KH domain NMD3 PF04981.8 EIE85666.1 - 1.6e-72 243.4 4.8 2.3e-72 242.9 3.3 1.2 1 0 0 1 1 1 1 NMD3 family Ribosomal_L24e PF01246.15 EIE85667.1 - 4e-30 103.4 4.7 9.6e-30 102.2 3.3 1.6 1 0 0 1 1 1 1 Ribosomal protein L24e FAD_binding_3 PF01494.14 EIE85668.1 - 4.2e-11 42.5 0.0 7.7e-11 41.6 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EIE85668.1 - 3e-08 32.9 0.3 6.3e-05 22.0 0.1 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EIE85668.1 - 6.1e-05 22.8 0.1 0.0016 18.2 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EIE85668.1 - 0.0014 17.5 0.0 0.0086 15.0 0.0 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EIE85668.1 - 0.0035 17.3 0.6 0.024 14.6 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EIE85668.1 - 0.0064 16.8 0.9 0.043 14.2 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EIE85668.1 - 0.0087 14.7 0.5 0.028 13.0 0.1 1.8 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox_2 PF07992.9 EIE85668.1 - 0.048 13.5 2.7 0.24 11.2 1.8 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SufE PF02657.10 EIE85668.1 - 0.055 13.0 0.0 0.18 11.4 0.0 1.8 2 0 0 2 2 2 0 Fe-S metabolism associated domain FAD_binding_2 PF00890.19 EIE85668.1 - 0.11 11.3 0.9 0.19 10.5 0.6 1.4 1 0 0 1 1 1 0 FAD binding domain SKI PF01202.17 EIE85670.1 - 9.4e-10 38.5 0.0 1.6e-09 37.8 0.0 1.4 1 1 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.1 EIE85670.1 - 4.6e-07 30.2 0.0 6.2e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EIE85670.1 - 7.4e-07 29.1 0.0 9.6e-07 28.7 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EIE85670.1 - 0.00033 21.4 0.0 0.0004 21.1 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EIE85670.1 - 0.0066 16.5 0.0 0.12 12.4 0.0 2.4 1 1 1 2 2 2 1 AAA domain dNK PF01712.14 EIE85670.1 - 0.01 15.7 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 0 Deoxynucleoside kinase AAA_28 PF13521.1 EIE85670.1 - 0.013 15.4 0.0 0.022 14.7 0.0 1.3 1 1 0 1 1 1 0 AAA domain tRNA_lig_kinase PF08303.6 EIE85670.1 - 0.021 14.7 0.4 0.099 12.5 0.1 2.2 2 1 0 2 2 2 0 tRNA ligase kinase domain AAA_5 PF07728.9 EIE85670.1 - 0.036 13.7 0.1 0.072 12.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EIE85670.1 - 0.037 13.1 0.1 0.42 9.7 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA PF00004.24 EIE85670.1 - 0.039 14.1 0.4 0.11 12.6 0.3 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) G-alpha PF00503.15 EIE85670.1 - 0.045 12.4 0.0 0.047 12.3 0.0 1.2 1 1 0 1 1 1 0 G-protein alpha subunit AAA_16 PF13191.1 EIE85670.1 - 0.06 13.3 0.1 0.15 11.9 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.7 EIE85670.1 - 0.072 12.1 0.3 0.27 10.2 0.1 2.1 2 1 0 2 2 2 0 Zeta toxin NACHT PF05729.7 EIE85670.1 - 0.11 12.2 0.2 0.21 11.2 0.1 1.7 1 1 1 2 2 2 0 NACHT domain AAA_14 PF13173.1 EIE85670.1 - 0.13 12.2 0.0 0.38 10.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain GRIM-19 PF06212.7 EIE85672.1 - 0.0055 16.4 0.5 0.013 15.2 0.3 1.6 1 0 0 1 1 1 1 GRIM-19 protein Laminin_II PF06009.7 EIE85672.1 - 0.38 10.5 7.7 0.072 12.8 2.5 1.7 2 0 0 2 2 2 0 Laminin Domain II COG2 PF06148.6 EIE85672.1 - 0.53 10.1 6.6 0.42 10.4 1.9 2.2 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Sec2p PF06428.6 EIE85672.1 - 1.2 8.9 8.6 1.9 8.4 3.3 2.8 2 1 1 3 3 3 0 GDP/GTP exchange factor Sec2p TPR_MLP1_2 PF07926.7 EIE85672.1 - 1.5 8.5 17.9 0.06 13.0 7.2 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein NOP5NT PF08156.8 EIE85672.1 - 4.4 7.5 6.6 3.6 7.8 0.2 3.1 1 1 2 3 3 3 0 NOP5NT (NUC127) domain MRP-L46 PF11788.3 EIE85673.1 - 1.7e-19 70.4 4.7 2.7e-19 69.8 3.1 1.4 1 1 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.23 EIE85673.1 - 2.4e-07 30.4 0.1 5.8e-07 29.2 0.0 1.6 2 0 0 2 2 2 1 NUDIX domain Tcp11 PF05794.8 EIE85673.1 - 0.064 11.9 1.2 0.091 11.4 0.8 1.2 1 0 0 1 1 1 0 T-complex protein 11 VEK-30 PF12107.3 EIE85674.1 - 0.11 12.2 0.9 0.22 11.2 0.6 1.5 1 0 0 1 1 1 0 Plasminogen (Pg) ligand in fibrinolytic pathway Polysacc_deac_1 PF01522.16 EIE85675.1 - 2.4e-35 120.8 0.0 4.2e-35 120.0 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 EIE85675.1 - 0.037 12.9 0.8 0.11 11.4 0.0 1.8 1 1 1 2 2 2 0 Glycosyl hydrolase family 57 Biotin_lipoyl PF00364.17 EIE85676.1 - 1.4e-19 69.5 0.1 3.7e-19 68.1 0.0 1.8 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.12 EIE85676.1 - 1.2e-06 28.0 0.1 2.6e-06 26.9 0.1 1.7 1 0 0 1 1 1 1 e3 binding domain 2-oxoacid_dh PF00198.18 EIE85676.1 - 0.00016 20.9 0.0 0.0025 17.1 0.0 2.1 2 0 0 2 2 2 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl_2 PF13533.1 EIE85676.1 - 0.00059 19.4 0.0 0.0018 17.9 0.0 1.8 1 0 0 1 1 1 1 Biotin-lipoyl like HlyD_3 PF13437.1 EIE85676.1 - 0.0023 18.2 0.8 0.098 13.0 0.0 3.0 2 1 1 3 3 3 1 HlyD family secretion protein HlyD PF00529.15 EIE85676.1 - 0.023 14.0 0.3 0.037 13.3 0.2 1.3 1 0 0 1 1 1 0 HlyD family secretion protein UFD1 PF03152.9 EIE85676.1 - 0.045 12.8 0.0 0.082 12.0 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin fusion degradation protein UFD1 YqgF PF14639.1 EIE85676.1 - 0.071 12.6 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Holliday-junction resolvase-like of SPT6 Cyclin PF08613.6 EIE85677.1 - 6e-16 59.1 0.1 9.5e-16 58.5 0.1 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EIE85677.1 - 5.1e-05 22.8 0.1 7.5e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain ubiquitin PF00240.18 EIE85678.1 - 8.5e-17 60.3 0.0 1.8e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 EIE85678.1 - 1.9e-08 33.8 0.2 4.5e-08 32.7 0.2 1.7 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.3 EIE85678.1 - 7.2e-08 32.0 0.1 1.6e-07 30.8 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EIE85678.1 - 0.00052 20.1 0.1 0.0009 19.3 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain XPC-binding PF09280.6 EIE85678.1 - 0.0028 17.0 8.9 0.014 14.7 5.9 2.5 1 1 0 1 1 1 1 XPC-binding domain DUF3446 PF11928.3 EIE85678.1 - 0.005 17.0 3.3 0.014 15.6 2.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3446) Rad60-SLD_2 PF13881.1 EIE85678.1 - 0.0077 16.1 0.1 0.015 15.2 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like L27_2 PF09045.5 EIE85678.1 - 0.09 12.3 0.1 3.1 7.4 0.0 2.5 2 0 0 2 2 2 0 L27_2 CUE PF02845.11 EIE85678.1 - 0.11 12.0 0.0 0.27 10.7 0.0 1.7 1 0 0 1 1 1 0 CUE domain SspH PF08141.7 EIE85678.1 - 0.13 12.3 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Small acid-soluble spore protein H family DUF3439 PF11921.3 EIE85678.1 - 0.24 11.1 11.3 0.56 9.9 7.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mucin PF01456.12 EIE85678.1 - 4.9 6.9 18.9 11 5.7 13.1 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein Dynamin_N PF00350.18 EIE85679.1 - 2.3e-19 69.8 0.0 1.2e-18 67.5 0.0 2.0 1 1 0 1 1 1 1 Dynamin family EF-hand_4 PF12763.2 EIE85679.1 - 1.4e-17 63.2 0.0 6.8e-17 61.1 0.0 2.1 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand MMR_HSR1 PF01926.18 EIE85679.1 - 1.7e-09 37.6 0.0 7.9e-09 35.4 0.0 2.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EIE85679.1 - 5e-06 26.9 0.0 0.017 15.5 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein GTP_EFTU PF00009.22 EIE85679.1 - 2.5e-05 23.8 0.0 5.8e-05 22.6 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EIE85679.1 - 0.00029 20.0 0.0 0.00053 19.1 0.0 1.5 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region EF-hand_1 PF00036.27 EIE85679.1 - 0.019 14.2 0.0 0.071 12.4 0.0 2.1 1 0 0 1 1 1 0 EF hand AAA_22 PF13401.1 EIE85679.1 - 0.053 13.6 0.0 0.24 11.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 EIE85679.1 - 0.057 13.0 0.0 0.18 11.4 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_28 PF13521.1 EIE85679.1 - 0.073 13.0 0.0 0.32 10.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 EIE85679.1 - 0.083 12.3 0.0 4.5 6.7 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 EIE85679.1 - 0.094 11.9 0.5 1.3 8.2 0.0 2.6 3 1 1 4 4 4 0 Signal recognition particle receptor beta subunit Ras PF00071.17 EIE85679.1 - 0.11 11.8 0.2 14 5.0 0.0 2.3 2 0 0 2 2 2 0 Ras family TRAPP PF04051.11 EIE85680.1 - 2.2e-31 108.4 0.2 4.7e-25 87.8 0.0 2.0 1 1 1 2 2 2 2 Transport protein particle (TRAPP) component Kelch_6 PF13964.1 EIE85681.1 - 4.3e-19 67.8 7.2 1.1e-07 31.7 0.1 5.1 3 1 2 5 5 5 4 Kelch motif Kelch_4 PF13418.1 EIE85681.1 - 5.3e-18 64.5 0.6 0.00015 21.4 0.0 3.9 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_5 PF13854.1 EIE85681.1 - 4.4e-17 61.6 1.3 1.9e-05 24.5 0.0 4.5 4 0 0 4 4 4 3 Kelch motif Kelch_1 PF01344.20 EIE85681.1 - 1.8e-14 53.0 0.8 3.2e-05 23.3 0.1 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.1 EIE85681.1 - 1.9e-14 53.3 1.9 6.6e-09 35.6 0.0 4.5 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_2 PF07646.10 EIE85681.1 - 2.5e-10 39.6 3.1 0.00015 21.3 0.0 4.3 5 1 0 5 5 5 2 Kelch motif BTB PF00651.26 EIE85681.1 - 4.9e-07 29.7 0.2 1e-06 28.6 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain RAG2 PF03089.9 EIE85681.1 - 0.00033 19.4 0.0 0.00065 18.5 0.0 1.4 1 0 0 1 1 1 1 Recombination activating protein 2 DUF2738 PF10927.3 EIE85681.1 - 0.082 11.9 0.1 0.15 11.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2738) F-box PF00646.28 EIE85682.1 - 0.00037 20.0 0.3 0.00083 18.9 0.2 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EIE85682.1 - 0.0046 16.6 1.6 0.0087 15.7 1.1 1.5 1 0 0 1 1 1 1 F-box-like WD40 PF00400.27 EIE85683.1 - 4.2e-37 124.7 17.6 2e-10 40.1 0.3 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIIIC_delta PF12657.2 EIE85683.1 - 4.9e-06 26.3 7.9 0.0053 16.4 0.1 3.5 2 1 0 3 3 3 2 Transcription factor IIIC subunit delta N-term YmzC PF14157.1 EIE85683.1 - 0.078 12.8 0.1 5.4 6.9 0.0 3.5 4 0 0 4 4 4 0 YmzC-like protein SUKH_5 PF14567.1 EIE85683.1 - 0.11 11.9 0.3 0.2 11.1 0.2 1.5 1 0 0 1 1 1 0 SMI1-KNR4 cell-wall XG_FTase PF03254.8 EIE85685.1 - 1.4e-09 37.0 0.0 0.00068 18.2 0.0 3.0 3 0 0 3 3 3 3 Xyloglucan fucosyltransferase PLDc_2 PF13091.1 EIE85686.1 - 1.9e-08 34.1 1.0 8.8e-08 31.9 0.7 2.1 1 1 0 1 1 1 1 PLD-like domain PX PF00787.19 EIE85686.1 - 3.2e-07 30.1 0.0 1.1e-06 28.4 0.0 1.9 1 0 0 1 1 1 1 PX domain PLDc PF00614.17 EIE85686.1 - 4.4e-06 26.3 0.2 1.2e-05 24.9 0.1 1.7 1 0 0 1 1 1 1 Phospholipase D Active site motif PH PF00169.24 EIE85686.1 - 0.013 15.6 0.3 0.051 13.7 0.2 2.0 1 0 0 1 1 1 0 PH domain Med3 PF11593.3 EIE85686.1 - 0.6 9.2 4.0 1.1 8.4 2.8 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal zf-RVT PF13966.1 EIE85687.1 - 0.00042 20.5 0.9 0.00094 19.4 0.6 1.6 1 1 0 1 1 1 1 zinc-binding in reverse transcriptase HPIP PF15226.1 EIE85687.1 - 0.48 10.4 3.2 0.5 10.4 0.8 2.0 2 0 0 2 2 2 0 HCF-1 beta-propeller-interacting protein family Ribosomal_L37 PF08561.5 EIE85688.1 - 0.12 12.0 1.6 0.29 10.7 1.1 1.7 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L37 PX PF00787.19 EIE85689.1 - 6.4e-21 74.2 0.1 6.4e-21 74.2 0.1 2.5 3 1 0 3 3 3 1 PX domain BAF1_ABF1 PF04684.8 EIE85689.1 - 0.0044 15.9 10.4 0.0061 15.4 7.2 1.2 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor Suf PF05843.9 EIE85689.1 - 0.27 10.9 12.5 0.18 11.5 6.9 1.9 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Folate_carrier PF01770.13 EIE85689.1 - 0.36 9.2 2.5 0.7 8.3 1.8 1.4 1 0 0 1 1 1 0 Reduced folate carrier DUF4557 PF15101.1 EIE85689.1 - 0.38 10.5 10.5 0.076 12.8 4.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) DUF3347 PF11827.3 EIE85689.1 - 0.85 9.5 11.9 0.061 13.3 3.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3347) VIT1 PF01988.14 EIE85689.1 - 1.3 8.4 4.6 2.7 7.3 3.2 1.5 1 0 0 1 1 1 0 VIT family TFIIA PF03153.8 EIE85689.1 - 2.2 8.0 21.1 0.12 12.1 10.9 1.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.3 EIE85689.1 - 2.3 7.5 12.8 0.1 11.9 3.9 2.2 2 1 0 2 2 2 0 Spt20 family Sec2p PF06428.6 EIE85690.1 - 8.7e-09 35.1 22.8 8.7e-09 35.1 15.8 1.9 1 1 1 2 2 2 1 GDP/GTP exchange factor Sec2p V_ATPase_I PF01496.14 EIE85690.1 - 0.0021 15.9 16.8 0.0029 15.5 11.7 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family ATG16 PF08614.6 EIE85690.1 - 0.041 13.6 19.1 0.067 13.0 13.3 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF3584 PF12128.3 EIE85690.1 - 0.097 9.9 19.9 0.13 9.6 13.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_13 PF13166.1 EIE85690.1 - 0.11 10.9 19.7 0.15 10.4 13.6 1.1 1 0 0 1 1 1 0 AAA domain DUF1184 PF06683.6 EIE85690.1 - 0.13 11.8 4.2 0.12 12.0 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1184) Tubulin_C PF03953.12 EIE85690.1 - 0.18 11.8 1.4 0.42 10.6 0.7 1.9 2 0 0 2 2 1 0 Tubulin C-terminal domain LMBR1 PF04791.11 EIE85690.1 - 0.19 10.3 5.3 0.25 9.8 3.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein HAUS-augmin3 PF14932.1 EIE85690.1 - 0.21 10.7 20.7 0.33 10.1 14.4 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF342 PF03961.8 EIE85690.1 - 0.41 9.0 15.1 0.7 8.2 10.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Phage_GPO PF05929.6 EIE85690.1 - 0.98 8.6 13.7 1.7 7.7 9.5 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase IFT57 PF10498.4 EIE85690.1 - 2.1 7.0 26.0 1 8.0 5.6 2.1 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 APG6 PF04111.7 EIE85690.1 - 2.1 7.3 23.5 3.8 6.4 16.3 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 Spc7 PF08317.6 EIE85690.1 - 2.9 6.4 31.0 0.71 8.4 12.1 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Sec20 PF03908.8 EIE85690.1 - 4.3 7.1 11.8 3.8 7.2 3.0 2.6 1 1 1 2 2 2 0 Sec20 DUF4407 PF14362.1 EIE85690.1 - 4.8 6.0 14.4 7 5.5 10.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) BLOC1_2 PF10046.4 EIE85690.1 - 7.3 6.7 20.7 5.6 7.1 8.5 2.6 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3735 PF12537.3 EIE85690.1 - 8.3 6.5 6.0 3.9 7.5 1.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3735) Not1 PF04054.10 EIE85691.1 - 3.8e-138 460.4 5.4 1e-137 459.0 3.7 1.8 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 EIE85691.1 - 5.2e-51 172.1 6.5 5.8e-51 172.0 2.8 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) CK_II_beta PF01214.13 EIE85692.1 - 1.1e-42 145.6 0.1 2.7e-42 144.3 0.0 1.6 1 1 1 2 2 2 1 Casein kinase II regulatory subunit 3-HAO PF06052.7 EIE85692.1 - 0.12 11.8 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyanthranilic acid dioxygenase HSP70 PF00012.15 EIE85693.1 - 5.5e-274 909.6 9.6 6.2e-274 909.5 6.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EIE85693.1 - 1.6e-16 59.8 0.1 4.1e-15 55.1 0.0 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 EIE85693.1 - 0.0037 16.9 0.0 0.015 14.8 0.0 2.1 2 1 0 3 3 3 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 EIE85693.1 - 0.053 12.6 0.1 0.053 12.6 0.1 2.6 2 1 1 3 3 3 0 Hydantoinase/oxoprolinase StbA PF06406.6 EIE85693.1 - 0.1 11.5 1.3 0.6 9.0 0.0 2.3 2 0 0 2 2 2 0 StbA protein DUF1353 PF07087.6 EIE85694.1 - 0.098 12.1 0.1 0.31 10.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1353) HOOK PF05622.7 EIE85696.1 - 1e-31 109.5 106.2 2.3e-27 95.1 56.1 2.2 1 1 1 2 2 2 2 HOOK protein bZIP_1 PF00170.16 EIE85696.1 - 0.011 15.7 2.7 0.011 15.7 1.9 10.0 8 3 2 10 10 10 0 bZIP transcription factor CNH PF00780.17 EIE85697.1 - 3e-35 121.9 1.9 3e-35 121.9 1.3 1.6 2 0 0 2 2 2 1 CNH domain RhoGEF PF00621.15 EIE85697.1 - 3.7e-31 108.3 2.0 3.7e-31 108.3 1.4 2.6 3 0 0 3 3 3 1 RhoGEF domain PH_5 PF15405.1 EIE85697.1 - 1e-23 83.7 7.6 1.5e-12 47.6 0.8 3.2 2 1 1 3 3 3 2 Pleckstrin homology domain DEP PF00610.16 EIE85697.1 - 7e-13 48.1 0.1 1.9e-12 46.7 0.0 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) HSP70 PF00012.15 EIE85698.1 - 7.2e-09 34.1 0.0 3e-08 32.0 0.0 1.8 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 EIE85698.1 - 0.083 11.4 0.0 0.7 8.4 0.0 2.0 2 0 0 2 2 2 0 MreB/Mbl protein adh_short PF00106.20 EIE85699.1 - 3.4e-26 92.1 0.1 3.4e-26 92.1 0.1 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIE85699.1 - 3.8e-16 59.5 0.1 4.8e-16 59.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EIE85699.1 - 2.3e-08 33.7 0.1 1.9e-07 30.7 0.1 2.3 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EIE85699.1 - 1.6e-07 31.1 0.2 3.2e-07 30.1 0.1 1.5 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EIE85699.1 - 6.4e-05 23.0 0.0 9.5e-05 22.4 0.0 1.3 1 1 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 EIE85699.1 - 0.002 17.1 0.1 0.0032 16.3 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Proteasome PF00227.21 EIE85700.1 - 3.1e-62 209.2 0.3 4.5e-62 208.7 0.2 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EIE85700.1 - 5.7e-14 51.1 0.1 1e-13 50.3 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF3349 PF11829.3 EIE85700.1 - 0.034 14.5 0.2 0.51 10.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3349) IL6 PF00489.12 EIE85700.1 - 0.13 11.8 1.2 0.26 10.8 0.5 1.7 2 0 0 2 2 2 0 Interleukin-6/G-CSF/MGF family Noelin-1 PF12308.3 EIE85700.1 - 0.22 11.3 1.9 0.26 11.1 0.5 1.7 2 0 0 2 2 2 0 Neurogenesis glycoprotein DUF4604 PF15377.1 EIE85702.1 - 0.29 11.3 39.6 0.44 10.7 5.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) RNA_polI_A34 PF08208.6 EIE85702.1 - 0.9 9.1 59.8 0.23 11.1 10.5 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 Vfa1 PF08432.5 EIE85702.1 - 0.96 9.4 42.6 0.66 9.9 7.0 2.3 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Med19 PF10278.4 EIE85702.1 - 1.1 8.8 47.1 0.47 10.1 10.1 2.2 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 DUF3245 PF11595.3 EIE85703.1 - 9.5e-10 38.9 4.3 9.6e-10 38.9 2.7 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3245) XkdW PF09636.5 EIE85703.1 - 0.0072 16.1 0.4 0.01 15.7 0.3 1.3 1 0 0 1 1 1 1 XkdW protein G-patch_2 PF12656.2 EIE85703.1 - 0.094 12.5 0.0 0.094 12.5 0.0 2.7 2 1 0 3 3 3 0 DExH-box splicing factor binding site DUF4407 PF14362.1 EIE85703.1 - 3.1 6.6 5.8 3.2 6.6 4.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CP12 PF02672.10 EIE85705.1 - 0.095 13.1 0.2 0.28 11.6 0.2 1.7 1 0 0 1 1 1 0 CP12 domain Med14 PF08638.6 EIE85708.1 - 9.5e-38 129.4 0.8 4.1e-32 111.0 0.0 2.4 1 1 1 2 2 2 2 Mediator complex subunit MED14 Aldolase_II PF00596.16 EIE85709.1 - 1.3e-45 155.2 0.1 1.8e-45 154.7 0.0 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Tubulin PF00091.20 EIE85709.1 - 0.011 15.5 0.1 0.019 14.8 0.0 1.3 1 1 0 1 1 1 0 Tubulin/FtsZ family, GTPase domain G-patch PF01585.18 EIE85709.1 - 0.046 13.5 0.0 0.091 12.5 0.0 1.4 1 0 0 1 1 1 0 G-patch domain DUF3046 PF11248.3 EIE85709.1 - 0.065 13.2 0.2 2.3 8.2 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3046) rve PF00665.21 EIE85710.1 - 2.9e-23 82.2 0.0 7.1e-23 80.9 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE85710.1 - 8.4e-16 57.9 0.3 2e-15 56.7 0.2 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.12 EIE85710.1 - 0.00049 20.1 0.9 0.0023 17.9 0.6 2.2 1 0 0 1 1 1 1 Retrotransposon gag protein zf-H2C2 PF09337.5 EIE85710.1 - 0.0013 18.1 0.1 0.004 16.5 0.1 2.0 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Asp_protease_2 PF13650.1 EIE85710.1 - 0.0051 17.2 0.2 0.013 15.9 0.2 1.8 1 0 0 1 1 1 1 Aspartyl protease DUF2246 PF10229.4 EIE85710.1 - 0.0062 15.8 0.8 0.037 13.3 0.1 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2246) rve_3 PF13683.1 EIE85710.1 - 0.0074 15.7 0.2 0.048 13.2 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain UBN2_2 PF14227.1 EIE85710.1 - 0.022 14.3 5.6 0.047 13.2 0.0 3.3 3 0 0 3 3 3 0 gag-polypeptide of LTR copia-type Asp_protease PF09668.5 EIE85710.1 - 0.038 13.5 0.1 0.12 11.9 0.1 1.9 1 1 0 1 1 1 0 Aspartyl protease UBN2 PF14223.1 EIE85710.1 - 0.056 13.2 0.1 0.21 11.3 0.1 2.0 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type DivIC PF04977.10 EIE85711.1 - 0.0051 16.2 1.4 0.0096 15.3 1.0 1.4 1 0 0 1 1 1 1 Septum formation initiator SlyX PF04102.7 EIE85711.1 - 0.026 14.8 1.7 0.062 13.6 1.2 1.6 1 0 0 1 1 1 0 SlyX DUF4164 PF13747.1 EIE85711.1 - 0.047 13.8 1.9 5.3 7.2 0.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) TMF_TATA_bd PF12325.3 EIE85711.1 - 0.048 13.4 0.1 0.091 12.4 0.1 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 EIE85711.1 - 0.065 13.0 0.4 0.11 12.3 0.3 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Gag_spuma PF03276.9 EIE85711.1 - 0.4 8.9 8.4 0.53 8.5 5.8 1.1 1 0 0 1 1 1 0 Spumavirus gag protein MCPVI PF02993.9 EIE85711.1 - 4.3 7.4 7.3 5.8 7.0 5.0 1.1 1 0 0 1 1 1 0 Minor capsid protein VI Tau95 PF09734.4 EIE85712.1 - 1.4e-49 169.1 0.4 2.2e-49 168.5 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase III transcription factor (TF)IIIC subunit SNARE_assoc PF09335.6 EIE85713.1 - 1.1e-09 38.6 0.2 1.1e-09 38.6 0.2 1.5 2 0 0 2 2 2 1 SNARE associated Golgi protein cwf18 PF08315.7 EIE85714.1 - 7.6e-32 110.4 13.4 1e-31 110.0 9.3 1.2 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor PAS_10 PF13596.1 EIE85714.1 - 0.11 12.7 0.5 0.32 11.2 0.1 1.9 1 1 1 2 2 2 0 PAS domain ubiquitin PF00240.18 EIE85715.1 - 2.2e-68 225.5 8.2 6.6e-34 115.1 0.6 2.2 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.3 EIE85715.1 - 3.4e-39 132.3 7.0 2.5e-19 68.7 0.5 2.3 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EIE85715.1 - 3e-12 46.6 2.3 9.1e-05 22.6 0.1 3.2 2 2 0 2 2 2 2 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EIE85715.1 - 3.4e-10 39.8 0.4 0.0004 20.1 0.1 2.4 2 1 0 2 2 2 2 Telomere stability and silencing zf-AN1 PF01428.11 EIE85715.1 - 7.6e-10 38.4 10.0 1.2e-09 37.8 6.9 1.3 1 0 0 1 1 1 1 AN1-like Zinc finger Rad60-SLD_2 PF13881.1 EIE85715.1 - 1.1e-08 34.9 1.5 0.00035 20.4 0.3 2.7 2 2 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EIE85715.1 - 3.7e-07 30.2 1.9 0.0054 16.8 0.4 2.3 1 1 1 2 2 2 2 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 EIE85715.1 - 2.4e-05 24.2 0.1 0.15 12.1 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF2870) DUF3221 PF11518.3 EIE85715.1 - 0.0018 17.9 0.9 0.26 10.9 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3221) CpeS PF09367.5 EIE85715.1 - 0.0033 17.3 0.1 0.14 12.0 0.0 2.2 2 0 0 2 2 2 1 CpeS-like protein Plexin_cytopl PF08337.7 EIE85715.1 - 0.0035 15.7 4.4 1.5 7.0 0.2 3.4 3 1 0 3 3 3 2 Plexin cytoplasmic RasGAP domain TUG-UBL1 PF11470.3 EIE85715.1 - 0.0039 17.0 0.6 2.8 7.9 0.0 2.3 2 0 0 2 2 2 2 GLUT4 regulating protein TUG FlgD_ig PF13860.1 EIE85715.1 - 0.02 14.5 0.5 6.5 6.5 0.0 2.3 2 0 0 2 2 2 0 FlgD Ig-like domain DUF3861 PF12977.2 EIE85715.1 - 0.085 12.9 0.7 12 6.0 0.0 2.6 1 1 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3861) GABP-alpha PF11620.3 EIE85715.1 - 0.21 11.5 2.0 14 5.7 0.1 2.2 2 0 0 2 2 2 0 GA-binding protein alpha chain Tash_PEST PF07708.6 EIE85715.1 - 0.28 11.1 11.2 2.5 8.1 1.2 2.4 2 0 0 2 2 2 0 Tash protein PEST motif Ribosomal_L18e PF00828.14 EIE85716.1 - 1.7e-18 67.2 0.5 2.7e-18 66.5 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 zf-RING_2 PF13639.1 EIE85718.1 - 0.0014 18.3 0.4 0.0014 18.3 0.3 3.5 3 0 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.1 EIE85718.1 - 0.0037 16.9 0.2 0.0037 16.9 0.2 3.1 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EIE85718.1 - 0.036 14.0 0.3 0.036 14.0 0.2 3.5 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-UBR PF02207.15 EIE85719.1 - 1.1e-19 69.8 12.4 2.3e-19 68.8 8.6 1.6 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 EIE85719.1 - 1.2e-14 53.7 0.2 3.2e-14 52.3 0.1 1.8 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS SDA1 PF05285.7 EIE85719.1 - 0.84 8.8 11.4 1.3 8.2 7.9 1.2 1 0 0 1 1 1 0 SDA1 ECH PF00378.15 EIE85720.1 - 1.1e-49 168.7 0.0 1.7e-49 168.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 EIE85720.1 - 0.027 14.6 0.0 0.048 13.8 0.0 1.4 1 0 0 1 1 1 0 2-enoyl-CoA Hydratase C-terminal region CortBP2 PF09727.4 EIE85721.1 - 0.087 12.3 0.1 0.1 12.0 0.0 1.0 1 0 0 1 1 1 0 Cortactin-binding protein-2 RNase_P_p30 PF01876.11 EIE85723.1 - 3.6e-40 136.6 1.1 6.9e-40 135.7 0.6 1.6 1 1 0 1 1 1 1 RNase P subunit p30 Tom37 PF10568.4 EIE85724.1 - 1.1e-06 28.7 0.0 2.6e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_3 PF14497.1 EIE85724.1 - 6.5e-06 26.5 0.1 1.9e-05 25.0 0.1 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EIE85724.1 - 1.1e-05 25.2 0.0 2.2e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37_C PF11801.3 EIE85724.1 - 1.6e-05 24.8 0.2 0.0069 16.2 0.1 2.2 1 1 1 2 2 2 2 Tom37 C-terminal domain GST_N_2 PF13409.1 EIE85724.1 - 0.063 13.2 0.0 0.31 11.0 0.0 2.2 2 1 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Mito_carr PF00153.22 EIE85725.1 - 7.3e-69 227.5 3.2 8.7e-23 79.8 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.14 EIE85725.1 - 0.072 13.1 0.6 0.12 12.4 0.0 1.8 2 0 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family Pkinase PF00069.20 EIE85726.1 - 1.8e-26 92.8 2.2 2.1e-26 92.6 1.5 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE85726.1 - 2.8e-15 56.1 0.5 3.3e-15 55.8 0.4 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase RCC1 PF00415.13 EIE85727.1 - 1.9e-44 149.6 5.3 6.7e-09 35.8 0.0 8.1 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EIE85727.1 - 3.7e-24 83.7 15.6 1.2e-05 24.7 0.0 8.3 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat E2F_TDP PF02319.15 EIE85729.1 - 5.1e-24 83.6 0.1 1.2e-23 82.4 0.0 1.7 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain TrmB PF01978.14 EIE85729.1 - 0.0031 17.1 0.1 0.22 11.2 0.0 2.3 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB bZIP_1 PF00170.16 EIE85729.1 - 0.013 15.4 3.6 0.013 15.4 2.5 2.4 3 0 0 3 3 3 0 bZIP transcription factor DivIC PF04977.10 EIE85729.1 - 0.015 14.8 1.1 0.015 14.8 0.8 1.8 2 0 0 2 2 2 0 Septum formation initiator Snf7 PF03357.16 EIE85729.1 - 0.028 13.8 0.2 0.061 12.7 0.1 1.5 1 0 0 1 1 1 0 Snf7 Vma12 PF11712.3 EIE85729.1 - 0.063 12.9 0.7 0.084 12.5 0.5 1.3 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Cep57_CLD_2 PF14197.1 EIE85729.1 - 0.069 13.0 2.7 0.16 11.9 1.8 1.7 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 DUF342 PF03961.8 EIE85729.1 - 0.072 11.4 1.4 0.09 11.1 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Vac_Fusion PF02346.11 EIE85729.1 - 0.079 12.3 2.4 0.12 11.7 0.5 2.3 2 1 0 2 2 2 0 Chordopoxvirus fusion protein APG6 PF04111.7 EIE85729.1 - 0.086 11.8 4.2 0.12 11.4 2.9 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 EIE85729.1 - 0.22 11.0 2.4 0.3 10.6 1.6 1.3 1 0 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 EIE85729.1 - 0.3 8.8 2.2 0.32 8.8 1.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Viral_P18 PF04521.8 EIE85729.1 - 0.31 10.5 2.6 0.42 10.0 0.7 2.0 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein bZIP_2 PF07716.10 EIE85729.1 - 0.34 10.7 8.1 0.25 11.1 2.4 2.4 2 0 0 2 2 2 0 Basic region leucine zipper Prefoldin_2 PF01920.15 EIE85729.1 - 0.62 9.8 9.5 8.7 6.1 6.6 2.3 1 1 0 1 1 1 0 Prefoldin subunit GrpE PF01025.14 EIE85729.1 - 4.3 6.8 7.9 12 5.4 3.5 2.2 1 1 1 2 2 2 0 GrpE TPR_1 PF00515.23 EIE85730.1 - 9.5e-52 170.6 37.8 2.4e-08 33.2 0.0 11.3 11 1 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.12 EIE85730.1 - 3.1e-44 145.3 36.1 8.7e-06 25.2 0.0 10.5 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_11 PF13414.1 EIE85730.1 - 3.9e-43 144.9 31.9 7.1e-12 44.8 0.8 7.1 2 2 6 8 8 8 7 TPR repeat TPR_16 PF13432.1 EIE85730.1 - 3.4e-33 113.5 17.0 4.2e-09 36.8 0.1 6.8 4 1 3 7 7 7 7 Tetratricopeptide repeat TPR_8 PF13181.1 EIE85730.1 - 5.1e-31 104.1 34.6 5.7e-05 22.5 1.3 10.2 8 2 2 10 10 10 7 Tetratricopeptide repeat TPR_17 PF13431.1 EIE85730.1 - 2.4e-30 102.1 25.0 0.00019 21.3 0.1 10.2 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_12 PF13424.1 EIE85730.1 - 3.2e-28 97.4 29.5 4.5e-06 26.5 1.8 6.5 1 1 6 7 7 7 7 Tetratricopeptide repeat TPR_14 PF13428.1 EIE85730.1 - 3.7e-26 89.2 13.7 0.0014 19.0 0.1 9.1 4 2 6 10 10 10 7 Tetratricopeptide repeat TPR_19 PF14559.1 EIE85730.1 - 7.1e-22 77.5 21.7 4.2e-06 26.9 0.6 7.3 4 2 2 7 7 7 5 Tetratricopeptide repeat TPR_7 PF13176.1 EIE85730.1 - 2.8e-21 73.5 21.9 0.031 14.0 0.0 9.6 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_6 PF13174.1 EIE85730.1 - 4e-17 61.4 28.2 0.039 14.4 0.0 9.8 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_9 PF13371.1 EIE85730.1 - 4.8e-16 58.3 15.8 0.00057 19.6 0.2 6.4 4 2 3 7 7 7 5 Tetratricopeptide repeat Apc3 PF12895.2 EIE85730.1 - 1e-11 44.7 19.5 2.6e-06 27.4 2.1 4.3 3 1 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 EIE85730.1 - 5.9e-08 32.1 13.8 0.049 12.6 2.3 4.7 1 1 4 5 5 5 4 Tetratricopeptide repeat TPR_20 PF14561.1 EIE85730.1 - 3.4e-05 23.8 1.2 2.4 8.3 0.0 5.2 4 2 2 6 6 5 1 Tetratricopeptide repeat DUF2225 PF09986.4 EIE85730.1 - 0.00017 21.1 10.5 0.074 12.4 3.0 3.1 2 2 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2225) SNAP PF14938.1 EIE85730.1 - 0.00039 19.6 16.4 0.017 14.2 1.8 4.0 1 1 2 3 3 3 2 Soluble NSF attachment protein, SNAP TPR_21 PF09976.4 EIE85730.1 - 0.012 15.5 12.3 1.5 8.7 0.0 4.8 4 1 1 5 5 5 0 Tetratricopeptide repeat Tcf25 PF04910.9 EIE85730.1 - 0.069 12.0 5.0 0.98 8.2 0.0 3.4 3 1 0 3 3 3 0 Transcriptional repressor TCF25 ChAPs PF09295.5 EIE85730.1 - 0.081 11.6 3.0 1.8 7.2 0.1 3.0 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_10 PF13374.1 EIE85730.1 - 0.36 10.8 0.0 0.36 10.8 0.0 7.4 8 0 0 8 8 8 0 Tetratricopeptide repeat MIT PF04212.13 EIE85730.1 - 0.87 9.5 25.8 1.9 8.4 0.1 6.5 6 2 0 6 6 6 0 MIT (microtubule interacting and transport) domain BTAD PF03704.12 EIE85730.1 - 2.1 8.6 11.2 13 6.0 0.9 3.3 2 1 0 3 3 3 0 Bacterial transcriptional activator domain RPN7 PF10602.4 EIE85730.1 - 4.1 6.7 9.9 9.1 5.6 0.1 4.5 2 1 1 4 4 4 0 26S proteasome subunit RPN7 Xpo1 PF08389.7 EIE85731.1 - 0.00025 20.9 0.3 0.0034 17.3 0.0 3.1 3 0 0 3 3 3 1 Exportin 1-like protein CRM1_C PF08767.6 EIE85731.1 - 0.00079 18.4 1.4 0.0024 16.8 0.4 2.3 2 0 0 2 2 2 1 CRM1 C terminal IBN_N PF03810.14 EIE85731.1 - 0.0082 16.0 0.0 0.073 12.9 0.0 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT PF02985.17 EIE85731.1 - 0.055 13.5 0.0 11 6.3 0.0 3.5 2 0 0 2 2 2 0 HEAT repeat AMP-binding PF00501.23 EIE85733.1 - 6.2e-94 314.7 0.0 7.8e-94 314.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EIE85733.1 - 0.00045 21.0 0.0 0.012 16.5 0.0 2.8 1 1 1 2 2 2 1 AMP-binding enzyme C-terminal domain Atx10homo_assoc PF09759.4 EIE85734.1 - 8.3e-34 115.3 0.2 1.5e-33 114.5 0.1 1.4 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain Arm PF00514.18 EIE85734.1 - 0.0011 18.6 0.0 0.0044 16.8 0.0 2.1 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EIE85734.1 - 0.0017 18.5 0.0 0.0037 17.5 0.0 1.5 1 0 0 1 1 1 1 HEAT repeats HEAT PF02985.17 EIE85734.1 - 0.1 12.7 0.0 0.41 10.8 0.0 2.0 1 0 0 1 1 1 0 HEAT repeat Flagellin_N PF00669.15 EIE85735.1 - 0.086 12.6 0.2 0.14 11.9 0.2 1.3 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region Chordopox_G3 PF06129.7 EIE85735.1 - 0.25 11.4 2.7 8.3 6.6 0.1 2.7 2 1 0 2 2 2 0 Chordopoxvirus G3 protein DUF462 PF04315.7 EIE85736.1 - 0.12 11.7 0.0 0.15 11.4 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function, DUF462 Paramecium_SA PF01508.11 EIE85736.1 - 0.48 10.6 4.6 0.65 10.2 3.2 1.2 1 0 0 1 1 1 0 Paramecium surface antigen domain CRCB PF02537.10 EIE85737.1 - 0.09 12.6 0.1 0.09 12.6 0.0 1.1 1 0 0 1 1 1 0 CrcB-like protein HMG_box PF00505.14 EIE85738.1 - 2.3e-19 69.3 2.0 5.3e-19 68.2 1.4 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EIE85738.1 - 3.7e-07 30.4 0.8 3.7e-07 30.4 0.6 1.8 2 0 0 2 2 2 1 HMG-box domain Pribosyltran PF00156.22 EIE85739.1 - 3.1e-13 49.5 0.0 4.4e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_2 PF15609.1 EIE85739.1 - 0.0094 15.2 0.0 0.011 15.0 0.0 1.4 1 1 0 1 1 1 1 Phosphoribosyl transferase UPRTase PF14681.1 EIE85739.1 - 0.013 14.7 0.0 0.018 14.2 0.0 1.3 1 1 0 1 1 1 0 Uracil phosphoribosyltransferase Pkinase PF00069.20 EIE85741.1 - 1.1e-39 136.2 0.1 3.1e-39 134.7 0.1 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE85741.1 - 5.6e-21 74.7 0.0 9.1e-21 74.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE85741.1 - 0.039 12.9 0.0 0.055 12.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Peptidase_A2E PF12382.3 EIE85741.1 - 0.062 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Retrotransposon peptidase Mito_carr PF00153.22 EIE85742.1 - 3.5e-66 218.9 6.2 1.4e-23 82.4 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein HMG_box PF00505.14 EIE85743.1 - 1e-19 70.5 4.7 1e-19 70.5 3.3 1.7 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EIE85743.1 - 2.1e-09 37.6 3.2 5.1e-09 36.3 2.2 1.7 1 0 0 1 1 1 1 HMG-box domain NDK PF00334.14 EIE85744.1 - 1.9e-53 179.8 0.0 2.3e-53 179.6 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase MARVEL PF01284.18 EIE85745.1 - 4.2e-05 23.3 21.2 0.00011 22.0 14.4 1.8 1 1 1 2 2 2 1 Membrane-associating domain Tetraspannin PF00335.15 EIE85745.1 - 0.035 13.3 26.1 0.067 12.4 11.8 2.1 1 1 1 2 2 2 0 Tetraspanin family DUF1189 PF06691.6 EIE85745.1 - 2.7 7.2 11.2 0.73 9.1 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1189) PPR_2 PF13041.1 EIE85749.1 - 1.1e-41 140.5 0.3 6.9e-09 35.5 0.0 7.5 3 2 4 7 7 7 7 PPR repeat family PPR_3 PF13812.1 EIE85749.1 - 9.3e-23 78.5 3.1 6.9e-05 22.8 0.0 8.5 8 0 0 8 8 8 5 Pentatricopeptide repeat domain PPR PF01535.15 EIE85749.1 - 5.6e-21 72.9 0.3 0.00019 21.1 0.0 8.3 8 0 0 8 8 8 6 PPR repeat PPR_1 PF12854.2 EIE85749.1 - 9.4e-15 53.8 4.0 0.0058 16.0 0.0 6.7 7 1 0 7 7 7 5 PPR repeat CARD PF00619.16 EIE85749.1 - 0.022 14.5 0.0 0.59 9.9 0.0 3.2 2 0 0 2 2 2 0 Caspase recruitment domain TPR_16 PF13432.1 EIE85749.1 - 0.048 14.3 0.2 23 5.8 0.1 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 EIE85749.1 - 0.14 12.0 9.4 0.13 12.1 0.8 3.9 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 EIE85749.1 - 0.17 12.4 1.8 0.6 10.6 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat GNVR PF13807.1 EIE85749.1 - 0.3 10.8 1.7 4.1 7.2 0.3 3.1 3 0 0 3 3 3 0 G-rich domain on putative tyrosine kinase Mgm101p PF06420.7 EIE85751.1 - 6.9e-76 253.3 0.1 1.3e-75 252.4 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 HCV_NS5a_1a PF08300.8 EIE85752.1 - 0.12 12.2 8.6 0.062 13.2 3.6 2.3 2 0 0 2 2 2 0 Hepatitis C virus non-structural 5a zinc finger domain Codanin-1_C PF15296.1 EIE85753.1 - 0.027 14.3 4.6 0.54 10.1 3.3 2.4 1 1 1 2 2 2 0 Codanin-1 C-terminus Allexi_40kDa PF05549.6 EIE85753.1 - 0.4 9.9 3.5 2.3 7.4 0.1 2.2 1 1 1 2 2 2 0 Allexivirus 40kDa protein Nrap PF03813.9 EIE85754.1 - 5.1e-271 901.4 4.7 6.1e-271 901.2 3.2 1.1 1 0 0 1 1 1 1 Nrap protein Helicase_C PF00271.26 EIE85754.1 - 0.14 12.0 0.0 0.45 10.4 0.0 1.8 1 0 0 1 1 1 0 Helicase conserved C-terminal domain PBP1_TM PF14812.1 EIE85754.1 - 3.8 7.8 7.5 7.5 6.9 5.2 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal GCR1_C PF12550.3 EIE85755.1 - 0.044 13.6 0.0 0.078 12.8 0.0 1.4 1 0 0 1 1 1 0 Transcriptional activator of glycolytic enzymes Nop PF01798.13 EIE85756.1 - 2.4e-60 202.2 0.4 4.8e-60 201.2 0.3 1.5 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EIE85756.1 - 2.3e-24 84.9 0.1 4.7e-24 83.9 0.0 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EIE85756.1 - 2.2e-22 78.9 1.4 2.2e-22 78.9 0.9 2.7 2 0 0 2 2 2 1 NOP5NT (NUC127) domain RNA_polI_A34 PF08208.6 EIE85756.1 - 0.0034 17.0 30.4 0.006 16.2 21.0 1.5 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 RNase_H2-Ydr279 PF09468.5 EIE85756.1 - 0.055 12.6 19.0 0.12 11.5 13.2 1.6 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) GAGA_bind PF06217.7 EIE85756.1 - 0.11 12.3 12.1 0.21 11.5 8.4 1.5 1 0 0 1 1 1 0 GAGA binding protein-like family CT47 PF15623.1 EIE85756.1 - 1.8 8.2 19.7 2.6 7.6 13.6 1.3 1 0 0 1 1 1 0 Cancer/testis gene family 47 RR_TM4-6 PF06459.7 EIE85756.1 - 2.4 7.9 19.2 4 7.2 13.3 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Sec23_trunk PF04811.10 EIE85757.1 - 1.4e-76 257.0 0.0 2.2e-76 256.4 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EIE85757.1 - 3.4e-33 113.1 0.1 8.9e-33 111.8 0.1 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EIE85757.1 - 3.3e-31 107.6 0.5 8.6e-31 106.3 0.3 1.8 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EIE85757.1 - 3.7e-17 61.6 4.1 7.1e-17 60.6 2.8 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EIE85757.1 - 7.5e-13 47.9 0.0 2.9e-12 46.0 0.0 2.0 2 0 0 2 2 2 1 Gelsolin repeat Peptidase_M41 PF01434.13 EIE85757.1 - 0.029 13.8 0.8 0.064 12.7 0.5 1.5 1 0 0 1 1 1 0 Peptidase family M41 FAD_binding_8 PF08022.7 EIE85758.1 - 3.4e-14 52.5 0.0 7.4e-14 51.4 0.0 1.6 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EIE85758.1 - 1.7e-10 40.9 0.0 2e-09 37.5 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_6 PF00970.19 EIE85758.1 - 1.2e-06 28.6 0.0 2.3e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Ferric_reduct PF01794.14 EIE85758.1 - 0.0083 16.2 2.5 0.0093 16.0 1.0 1.6 1 1 0 1 1 1 1 Ferric reductase like transmembrane component HAD_2 PF13419.1 EIE85760.1 - 2.4e-23 83.2 0.0 2.9e-23 82.9 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EIE85760.1 - 2.1e-09 36.9 0.0 4.2e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EIE85760.1 - 0.0001 22.7 0.0 0.00091 19.6 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Pyr_redox_2 PF07992.9 EIE85761.1 - 3.1e-45 154.5 0.1 6.9e-45 153.4 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EIE85761.1 - 1.6e-42 143.9 1.1 2.7e-41 140.0 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 EIE85761.1 - 1.5e-20 73.3 11.1 1.8e-18 66.7 0.5 3.6 4 0 0 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EIE85761.1 - 8.4e-15 54.7 0.5 4.9e-11 42.3 0.2 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase GIDA PF01134.17 EIE85761.1 - 8.3e-12 44.6 5.5 1.3e-10 40.7 0.9 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EIE85761.1 - 1.4e-10 41.6 2.3 7.3e-06 26.1 0.5 2.9 1 1 2 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EIE85761.1 - 1.4e-09 37.3 14.6 5.3e-08 32.1 1.0 4.6 4 1 1 5 5 5 2 FAD binding domain Thi4 PF01946.12 EIE85761.1 - 9.7e-09 34.6 6.0 2.7e-07 29.9 0.2 2.7 1 1 1 2 2 2 2 Thi4 family NAD_binding_8 PF13450.1 EIE85761.1 - 9.2e-08 32.0 4.6 0.00016 21.6 0.2 2.9 3 0 0 3 3 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EIE85761.1 - 1.7e-07 30.5 7.0 0.021 13.8 0.3 3.3 3 0 0 3 3 3 3 FAD binding domain HI0933_like PF03486.9 EIE85761.1 - 4e-07 28.8 12.9 1.2e-05 24.0 0.5 4.1 4 0 0 4 4 4 2 HI0933-like protein DAO PF01266.19 EIE85761.1 - 2.4e-05 23.4 18.4 0.0011 17.9 0.7 4.1 2 2 1 4 4 4 3 FAD dependent oxidoreductase K_oxygenase PF13434.1 EIE85761.1 - 0.00056 18.9 0.1 0.2 10.5 0.0 2.6 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.16 EIE85761.1 - 0.00058 19.4 4.1 0.0066 16.0 0.1 3.1 2 1 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 EIE85761.1 - 0.0012 18.5 3.9 0.019 14.6 0.2 2.6 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 EIE85761.1 - 0.014 14.8 2.6 0.095 12.0 0.1 2.4 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.1 EIE85761.1 - 0.026 14.7 0.9 10 6.4 0.1 2.9 3 0 0 3 3 2 0 Putative NAD(P)-binding Lycopene_cycl PF05834.7 EIE85761.1 - 0.06 12.2 7.6 0.066 12.1 0.3 3.0 3 0 0 3 3 3 0 Lycopene cyclase protein C2 PF00168.25 EIE85762.1 - 5.4e-08 32.5 0.6 6.1e-06 26.0 0.0 2.9 2 1 1 3 3 3 2 C2 domain Pyr_redox_2 PF07992.9 EIE85763.1 - 8.5e-13 48.6 0.5 1.9e-08 34.4 0.0 3.1 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EIE85763.1 - 1.4e-05 25.2 0.1 0.099 12.6 0.0 3.0 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EIE85763.1 - 0.00011 21.9 0.0 0.36 10.5 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.19 EIE85763.1 - 0.0027 16.6 0.1 0.27 10.1 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EIE85763.1 - 0.0071 15.3 0.0 0.38 9.6 0.0 2.1 1 1 1 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.22 EIE85763.1 - 0.016 15.5 0.2 0.074 13.4 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIE85763.1 - 0.022 13.2 0.0 0.04 12.4 0.0 1.5 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.12 EIE85763.1 - 0.052 12.6 0.0 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.19 EIE85763.1 - 0.057 12.2 0.4 0.11 11.2 0.2 1.5 1 1 1 2 2 2 0 FAD binding domain NAD_binding_8 PF13450.1 EIE85763.1 - 0.088 12.8 0.0 0.39 10.7 0.0 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain RasGEF PF00617.14 EIE85764.1 - 4.7e-44 150.3 0.4 4.7e-44 150.3 0.3 2.2 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 EIE85764.1 - 7e-18 64.6 3.5 4.2e-17 62.1 2.4 2.4 1 0 0 1 1 1 1 RasGEF N-terminal motif HEAT_EZ PF13513.1 EIE85766.1 - 1e-06 29.0 0.5 0.066 13.7 0.0 4.5 3 2 2 5 5 5 3 HEAT-like repeat HEAT PF02985.17 EIE85766.1 - 5.8e-05 22.8 1.4 0.0022 17.9 0.0 3.7 3 0 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.1 EIE85766.1 - 0.0014 18.8 0.0 0.014 15.6 0.0 2.5 2 1 0 2 2 2 1 HEAT repeats Vac14_Fab1_bd PF12755.2 EIE85766.1 - 0.023 15.0 0.1 0.55 10.6 0.0 2.9 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region HEAT_PBS PF03130.11 EIE85766.1 - 0.059 13.8 0.6 1.3 9.6 0.0 3.2 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat DUF2435 PF10363.4 EIE85766.1 - 0.11 12.4 0.1 0.4 10.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2435) Pkinase PF00069.20 EIE85767.1 - 4.3e-61 206.3 0.0 5.2e-61 206.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE85767.1 - 2.6e-30 105.3 0.0 3.4e-30 105.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase YrbL-PhoP_reg PF10707.4 EIE85767.1 - 0.0071 15.7 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.18 EIE85767.1 - 0.06 13.0 0.0 0.094 12.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.1 EIE85767.1 - 0.11 11.4 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Abhydrolase_3 PF07859.8 EIE85768.1 - 3.5e-22 79.0 0.0 5e-22 78.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EIE85768.1 - 3.5e-07 29.2 0.1 1.9e-06 26.7 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EIE85768.1 - 0.074 12.7 0.0 0.099 12.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Kinesin PF00225.18 EIE85769.1 - 8.5e-72 241.6 23.4 1.3e-27 96.4 0.1 4.9 3 1 2 5 5 5 3 Kinesin motor domain zf-Tim10_DDP PF02953.10 EIE85771.1 - 5.5e-24 83.2 1.3 6.9e-24 82.9 0.9 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF2408 PF10303.4 EIE85771.1 - 0.015 15.4 1.5 0.017 15.1 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) Nsp1_C PF05064.8 EIE85771.1 - 0.68 9.5 3.4 2.2 7.9 1.4 2.1 1 1 2 3 3 3 0 Nsp1-like C-terminal region Peptidase_U4 PF03419.8 EIE85772.1 - 0.17 10.9 2.4 0.18 10.8 1.6 1.0 1 0 0 1 1 1 0 Sporulation factor SpoIIGA DUF2207 PF09972.4 EIE85773.1 - 0.13 10.7 0.0 0.16 10.5 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) CAML PF14963.1 EIE85773.1 - 0.17 11.2 0.9 0.23 10.7 0.6 1.1 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand Rep_fac-A_3 PF08661.6 EIE85775.1 - 0.014 15.2 0.1 0.016 15.0 0.0 1.1 1 0 0 1 1 1 0 Replication factor A protein 3 HEAT PF02985.17 EIE85776.1 - 8.9e-17 59.6 8.3 0.00026 20.8 0.1 7.2 7 0 0 7 7 7 4 HEAT repeat WD40 PF00400.27 EIE85776.1 - 1.6e-10 40.4 0.2 3.5e-10 39.3 0.2 1.6 1 0 0 1 1 1 1 WD domain, G-beta repeat HEAT_2 PF13646.1 EIE85776.1 - 2.2e-10 40.6 0.0 0.0015 18.7 0.0 3.7 2 2 1 3 3 3 3 HEAT repeats HEAT_EZ PF13513.1 EIE85776.1 - 5.1e-07 29.9 0.7 0.0024 18.2 0.4 4.0 3 0 0 3 3 3 1 HEAT-like repeat Cnd1 PF12717.2 EIE85776.1 - 2.7e-05 24.0 7.0 0.64 9.8 0.1 5.3 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Pkinase PF00069.20 EIE85776.1 - 2.9e-05 23.3 0.0 5.6e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain DUF2435 PF10363.4 EIE85776.1 - 0.0038 17.1 2.0 1.2 9.0 0.0 3.9 3 0 0 3 3 3 1 Protein of unknown function (DUF2435) WD40 PF00400.27 EIE85777.1 - 1.5e-09 37.3 0.0 0.00013 21.7 0.0 2.2 2 0 0 2 2 2 2 WD domain, G-beta repeat Peptidase_S8 PF00082.17 EIE85778.1 - 5e-48 163.6 17.3 7.3e-48 163.1 12.0 1.2 1 0 0 1 1 1 1 Subtilase family CD20 PF04103.10 EIE85778.1 - 1.3 8.9 6.6 2.3 8.1 0.7 2.4 2 0 0 2 2 2 0 CD20-like family Ribosomal_L7Ae PF01248.21 EIE85780.1 - 8.4e-28 95.7 1.9 1.1e-27 95.4 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF1193 PF06702.7 EIE85780.1 - 0.043 13.2 0.1 0.061 12.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1193) FliM PF02154.10 EIE85780.1 - 0.11 12.1 0.0 0.23 11.0 0.0 1.5 1 1 0 1 1 1 0 Flagellar motor switch protein FliM Ribosomal_S7e PF01251.13 EIE85781.1 - 7.3e-83 276.7 0.3 8.2e-83 276.5 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e TFIIS_M PF07500.9 EIE85782.1 - 2.6e-24 85.4 0.9 2.6e-24 85.4 0.7 2.8 3 1 1 4 4 4 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.8 EIE85782.1 - 3.2e-15 56.6 0.0 7.8e-15 55.3 0.0 1.7 1 0 0 1 1 1 1 SPOC domain Atrophin-1 PF03154.10 EIE85782.1 - 5 5.1 18.6 1.6 6.8 9.8 2.0 2 0 0 2 2 2 0 Atrophin-1 family DUF876 PF05936.7 EIE85783.1 - 0.016 13.6 0.0 0.019 13.4 0.0 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF876) Med15_fungi PF05397.7 EIE85784.1 - 7.4e-17 61.3 4.4 7.4e-17 61.3 3.0 4.2 4 1 0 4 4 4 1 Mediator complex subunit 15 Med15 PF09606.5 EIE85784.1 - 1.4 7.0 110.2 0.0047 15.2 55.9 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal VIT1 PF01988.14 EIE85784.1 - 1.6 8.1 6.7 3.2 7.1 4.7 1.5 1 0 0 1 1 1 0 VIT family Mtc PF03820.12 EIE85785.1 - 1.1e-91 306.6 3.9 1.3e-91 306.5 2.7 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier Aminotran_1_2 PF00155.16 EIE85786.1 - 2.9e-24 85.6 0.0 7.7e-24 84.3 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II p450 PF00067.17 EIE85788.1 - 3.8e-100 335.5 0.1 5.6e-100 335.0 0.1 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.15 EIE85788.1 - 3.9e-38 131.0 0.0 7.6e-38 130.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EIE85788.1 - 3.2e-22 79.0 1.3 3.2e-22 79.0 0.9 2.5 2 1 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.16 EIE85788.1 - 4.7e-15 56.0 0.0 1.1e-14 54.8 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain HSF_DNA-bind PF00447.12 EIE85789.1 - 4.3e-34 116.7 1.2 1.1e-33 115.5 0.8 1.7 1 0 0 1 1 1 1 HSF-type DNA-binding ATP-grasp_4 PF13535.1 EIE85790.1 - 0.0088 15.7 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ThiF PF00899.16 EIE85791.1 - 2.5e-37 127.7 0.8 3e-37 127.4 0.1 1.4 2 0 0 2 2 2 1 ThiF family Saccharop_dh PF03435.13 EIE85791.1 - 3.1e-06 26.4 0.2 8.4e-06 25.0 0.1 1.5 1 1 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 EIE85791.1 - 0.0041 17.2 0.3 0.016 15.2 0.0 2.1 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 EIE85791.1 - 0.0063 15.6 0.1 0.0094 15.0 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EIE85791.1 - 0.0077 15.1 0.5 0.012 14.5 0.3 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 EIE85791.1 - 0.014 15.6 0.3 0.04 14.1 0.0 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 EIE85791.1 - 0.023 14.1 0.2 0.058 12.7 0.0 1.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.13 EIE85791.1 - 0.033 14.1 0.0 0.092 12.7 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.13 EIE85791.1 - 0.035 13.7 0.2 0.11 12.1 0.0 1.9 2 1 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 EIE85791.1 - 0.067 12.6 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.9 EIE85791.1 - 0.098 12.5 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Adaptin_N PF01602.15 EIE85792.1 - 5.9e-98 328.4 9.9 8.3e-98 327.9 6.9 1.2 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 EIE85792.1 - 5e-54 182.2 3.6 1.1e-53 181.1 2.5 1.6 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 EIE85792.1 - 6.4e-19 68.0 5.1 2e-05 24.8 0.1 4.8 4 1 1 5 5 5 3 HEAT repeats HEAT_EZ PF13513.1 EIE85792.1 - 4.3e-08 33.4 3.7 0.0036 17.7 0.2 4.9 3 1 1 4 4 4 2 HEAT-like repeat HEAT PF02985.17 EIE85792.1 - 2.8e-06 26.9 9.9 1.1 9.4 0.0 6.9 7 0 0 7 7 7 2 HEAT repeat HEAT_PBS PF03130.11 EIE85792.1 - 1.3e-05 25.1 0.3 7.3 7.3 0.1 4.8 4 0 0 4 4 4 2 PBS lyase HEAT-like repeat Cnd1 PF12717.2 EIE85792.1 - 0.00083 19.2 9.4 0.36 10.6 0.3 4.1 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 EIE85792.1 - 0.0011 18.6 0.0 8.1 6.4 0.0 4.8 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat DUF3730 PF12530.3 EIE85792.1 - 0.35 10.7 6.8 7.7 6.3 0.2 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3730) RVT_1 PF00078.22 EIE85793.1 - 0.063 12.6 0.0 0.084 12.2 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) OrfB_Zn_ribbon PF07282.6 EIE85794.1 - 0.00039 20.0 0.0 0.00081 18.9 0.0 1.5 1 0 0 1 1 1 1 Putative transposase DNA-binding domain Zn_Tnp_IS1595 PF12760.2 EIE85794.1 - 0.11 12.3 2.3 0.17 11.6 0.1 2.1 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DUF4070 PF13282.1 EIE85798.1 - 0.13 11.8 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4070) BA14K PF07886.6 EIE85802.1 - 0.094 12.3 1.7 0.14 11.8 0.4 1.9 2 0 0 2 2 2 0 BA14K-like protein DUF4014 PF13198.1 EIE85803.1 - 0.021 15.1 1.5 0.25 11.8 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4014) DUF1925 PF09094.6 EIE85803.1 - 0.079 12.9 0.3 0.094 12.7 0.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1925) Phage_int_SAM_1 PF02899.12 EIE85804.1 - 0.00022 21.3 0.0 0.0021 18.1 0.0 2.0 2 0 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain HTH_Tnp_Tc3_2 PF01498.13 EIE85805.1 - 2.9e-07 30.4 3.3 5e-07 29.6 0.5 2.2 1 1 1 2 2 2 1 Transposase HTH_Tnp_Tc3_2 PF01498.13 EIE85806.1 - 1.5e-06 28.1 0.5 1.5e-06 28.1 0.4 1.9 2 1 0 2 2 2 1 Transposase HTH_Tnp_4 PF13613.1 EIE85806.1 - 0.0011 18.4 0.0 0.0025 17.3 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease HTH_23 PF13384.1 EIE85806.1 - 0.025 14.2 0.0 0.068 12.8 0.0 1.7 1 0 0 1 1 1 0 Homeodomain-like domain PIF1 PF05970.9 EIE85807.1 - 4.7e-33 114.6 0.2 2.6e-29 102.3 0.1 2.3 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 EIE85807.1 - 2.6e-17 63.0 0.0 5.2e-17 62.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EIE85807.1 - 4.4e-05 23.1 0.0 8.2e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain Viral_helicase1 PF01443.13 EIE85807.1 - 0.00017 21.1 0.0 0.00057 19.4 0.0 1.9 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 EIE85807.1 - 0.00033 20.7 0.0 0.00064 19.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EIE85807.1 - 0.0083 16.9 0.0 0.018 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain PhoH PF02562.11 EIE85807.1 - 0.011 15.0 0.0 0.067 12.4 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein AAA_14 PF13173.1 EIE85807.1 - 0.011 15.5 0.0 0.027 14.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EIE85807.1 - 0.014 15.6 0.0 0.028 14.6 0.0 1.7 1 1 0 1 1 1 0 ABC transporter Sigma54_activat PF00158.21 EIE85807.1 - 0.03 13.8 0.0 0.063 12.7 0.0 1.6 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_28 PF13521.1 EIE85807.1 - 0.03 14.2 0.0 0.053 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 EIE85807.1 - 0.037 14.0 0.1 0.11 12.5 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_16 PF13191.1 EIE85807.1 - 0.039 13.9 0.0 0.062 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Helicase_RecD PF05127.9 EIE85807.1 - 0.043 13.4 0.4 2.8 7.5 0.2 2.3 1 1 1 2 2 2 0 Helicase AAA_18 PF13238.1 EIE85807.1 - 0.045 14.0 0.0 0.095 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF853 PF05872.7 EIE85807.1 - 0.055 11.8 0.0 0.079 11.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) AAA_5 PF07728.9 EIE85807.1 - 0.12 12.1 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Transposase_21 PF02992.9 EIE85808.1 - 1.7e-18 66.5 0.0 3.1e-18 65.7 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 BLUF PF04940.7 EIE85811.1 - 0.036 13.7 0.1 0.043 13.5 0.0 1.1 1 0 0 1 1 1 0 Sensors of blue-light using FAD Transposase_21 PF02992.9 EIE85812.1 - 2.5e-23 82.3 0.1 2.5e-23 82.3 0.1 1.7 2 0 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.1 EIE85812.1 - 1.8e-05 24.1 0.5 3.9e-05 23.0 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) DUF1759 PF03564.10 EIE85813.1 - 0.00021 21.1 0.4 0.00021 21.1 0.3 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1759) Asp_protease_2 PF13650.1 EIE85814.1 - 1.7e-07 31.6 0.0 3.3e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EIE85814.1 - 6.3e-05 22.7 0.1 0.00012 21.7 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.5 EIE85814.1 - 0.0002 20.9 0.0 0.00028 20.4 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 EIE85814.1 - 0.0093 15.8 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease DDE_Tnp_IS1595 PF12762.2 EIE85815.1 - 1.1e-22 80.4 0.8 2e-22 79.6 0.3 1.6 2 0 0 2 2 2 1 ISXO2-like transposase domain NurA PF09376.5 EIE85816.1 - 0.034 13.6 0.5 0.039 13.4 0.4 1.2 1 0 0 1 1 1 0 NurA domain DUF4119 PF13494.1 EIE85816.1 - 0.12 12.3 3.1 0.16 11.9 0.8 2.1 1 1 1 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF4119) WD40 PF00400.27 EIE85817.1 - 0.077 12.9 1.3 0.16 11.8 0.9 1.5 1 0 0 1 1 1 0 WD domain, G-beta repeat DDE_3 PF13358.1 EIE85818.1 - 6.8e-10 38.8 2.3 2.3e-09 37.1 0.6 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_3 PF13358.1 EIE85819.1 - 2e-16 60.0 0.0 2.3e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE85819.1 - 0.078 13.0 0.0 0.55 10.3 0.0 2.2 1 1 0 1 1 1 0 Integrase core domain DDE_Tnp_IS1595 PF12762.2 EIE85821.1 - 1.1e-22 80.4 0.8 2e-22 79.6 0.3 1.6 2 0 0 2 2 2 1 ISXO2-like transposase domain RVT_1 PF00078.22 EIE85822.1 - 4.7e-19 68.6 0.0 8.1e-19 67.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EIE85822.1 - 1.7e-05 24.4 0.0 3.8e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase TPR_MLP1_2 PF07926.7 EIE85823.1 - 0.00012 21.7 0.4 0.00019 21.1 0.3 1.2 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein Phage_GP20 PF06810.6 EIE85823.1 - 0.00028 20.3 0.3 0.0004 19.8 0.2 1.2 1 0 0 1 1 1 1 Phage minor structural protein GP20 Med4 PF10018.4 EIE85823.1 - 0.00082 18.8 0.1 0.0011 18.3 0.1 1.2 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 DUF972 PF06156.8 EIE85823.1 - 0.0086 16.4 0.6 0.015 15.6 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF972) DivIVA PF05103.8 EIE85823.1 - 0.017 15.2 0.2 0.027 14.5 0.1 1.4 1 0 0 1 1 1 0 DivIVA protein Cluap1 PF10234.4 EIE85823.1 - 0.019 14.1 0.2 0.027 13.6 0.2 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 DivIC PF04977.10 EIE85823.1 - 0.033 13.6 0.2 0.064 12.7 0.1 1.5 1 0 0 1 1 1 0 Septum formation initiator HALZ PF02183.13 EIE85823.1 - 0.04 13.6 1.5 0.1 12.3 1.1 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper Mito_fiss_reg PF05308.6 EIE85823.1 - 0.042 13.2 1.0 0.06 12.6 0.7 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator SlyX PF04102.7 EIE85823.1 - 0.044 14.1 0.4 0.12 12.7 0.3 1.8 1 0 0 1 1 1 0 SlyX MAD PF05557.8 EIE85823.1 - 0.065 11.3 0.8 0.098 10.7 0.6 1.2 1 0 0 1 1 1 0 Mitotic checkpoint protein Rogdi_lz PF10259.4 EIE85823.1 - 0.067 12.2 1.5 0.1 11.6 1.0 1.2 1 0 0 1 1 1 0 Rogdi leucine zipper containing protein DUF1875 PF08961.5 EIE85823.1 - 0.092 12.0 0.1 0.14 11.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1875) Baculo_PEP_C PF04513.7 EIE85823.1 - 0.13 12.0 9.5 0.24 11.2 6.6 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 EIE85823.1 - 0.57 9.3 6.3 0.79 8.8 4.4 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein rve PF00665.21 EIE85825.1 - 2.6e-20 72.6 0.0 1.4e-19 70.3 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 EIE85825.1 - 5.4e-11 42.2 0.3 1.9e-10 40.4 0.2 1.9 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE85825.1 - 3e-07 30.0 2.4 6.5e-07 28.9 1.6 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 EIE85825.1 - 0.0044 16.6 1.0 0.015 15.0 0.7 1.9 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain rve_3 PF13683.1 EIE85825.1 - 0.0088 15.5 0.0 0.033 13.7 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain HTH_Tnp_Tc3_2 PF01498.13 EIE85827.1 - 8.6e-11 41.7 0.3 1.8e-10 40.7 0.2 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.1 EIE85827.1 - 9.4e-11 41.6 0.5 2.3e-10 40.4 0.3 1.7 1 1 0 1 1 1 1 DDE superfamily endonuclease TPR_MLP1_2 PF07926.7 EIE85828.1 - 0.00011 21.8 1.7 0.00018 21.2 1.2 1.2 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein Phage_GP20 PF06810.6 EIE85828.1 - 0.00051 19.5 0.2 0.00079 18.9 0.1 1.2 1 0 0 1 1 1 1 Phage minor structural protein GP20 Med4 PF10018.4 EIE85828.1 - 0.0098 15.3 0.1 0.014 14.8 0.0 1.2 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 DUF972 PF06156.8 EIE85828.1 - 0.016 15.5 0.6 0.027 14.8 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Baculo_PEP_C PF04513.7 EIE85828.1 - 0.02 14.7 7.1 0.032 14.0 4.9 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus SlyX PF04102.7 EIE85828.1 - 0.021 15.1 0.2 0.055 13.8 0.1 1.7 1 0 0 1 1 1 0 SlyX Birna_RdRp PF04197.7 EIE85828.1 - 0.028 12.4 1.2 0.036 12.1 0.9 1.1 1 0 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) DivIVA PF05103.8 EIE85828.1 - 0.044 13.8 0.1 0.076 13.0 0.1 1.4 1 0 0 1 1 1 0 DivIVA protein DivIC PF04977.10 EIE85828.1 - 0.047 13.1 0.3 0.088 12.2 0.2 1.4 1 0 0 1 1 1 0 Septum formation initiator HALZ PF02183.13 EIE85828.1 - 0.049 13.3 0.8 0.12 12.0 0.6 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper Reo_sigmaC PF04582.7 EIE85828.1 - 0.057 12.6 3.4 0.078 12.1 2.3 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Cluap1 PF10234.4 EIE85828.1 - 0.062 12.5 1.5 0.088 12.0 1.0 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 Rogdi_lz PF10259.4 EIE85828.1 - 0.068 12.2 2.3 0.11 11.6 1.6 1.3 1 0 0 1 1 1 0 Rogdi leucine zipper containing protein ADIP PF11559.3 EIE85828.1 - 0.39 10.6 3.8 0.81 9.5 2.6 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Exo_endo_phos_2 PF14529.1 EIE85829.1 - 2e-13 49.9 0.0 3.9e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EIE85829.1 - 2.3 8.0 10.6 41 3.9 7.3 2.1 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family DUF2816 PF10992.3 EIE85830.1 - 0.092 12.3 0.3 0.14 11.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2816) RVT_1 PF00078.22 EIE85831.1 - 7.8e-15 54.8 0.3 8.4e-07 28.5 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Spuma_A9PTase PF03539.9 EIE85831.1 - 0.00071 19.5 0.3 0.0023 17.8 0.1 1.9 1 1 1 2 2 2 1 Spumavirus aspartic protease (A9) rve PF00665.21 EIE85832.1 - 8.1e-28 96.9 0.0 2.8e-27 95.1 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.1 EIE85832.1 - 1.4e-05 24.5 0.1 5.4e-05 22.6 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.5 EIE85832.1 - 0.0027 17.0 0.1 0.013 14.9 0.0 2.2 2 0 0 2 2 2 1 His(2)-Cys(2) zinc finger RVT_1 PF00078.22 EIE85833.1 - 3.8e-22 78.7 0.0 5.9e-22 78.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TPR_MLP1_2 PF07926.7 EIE85834.1 - 0.0004 20.1 0.7 0.00053 19.7 0.5 1.2 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein HALZ PF02183.13 EIE85834.1 - 0.00046 19.8 1.2 0.00095 18.8 0.4 1.9 1 1 1 2 2 2 1 Homeobox associated leucine zipper Reo_sigmaC PF04582.7 EIE85834.1 - 0.0014 17.8 4.4 0.0019 17.4 3.0 1.1 1 0 0 1 1 1 1 Reovirus sigma C capsid protein CCDC155 PF14662.1 EIE85834.1 - 0.0038 16.8 1.2 0.0055 16.3 0.9 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 ADIP PF11559.3 EIE85834.1 - 0.0048 16.7 2.1 0.0077 16.1 1.5 1.3 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding DUF904 PF06005.7 EIE85834.1 - 0.0053 17.0 2.3 0.011 16.0 1.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF904) DUF972 PF06156.8 EIE85834.1 - 0.012 15.9 0.4 0.022 15.1 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Phage_GP20 PF06810.6 EIE85834.1 - 0.023 14.1 0.7 0.035 13.5 0.5 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 GAS PF13851.1 EIE85834.1 - 0.023 13.8 1.0 0.034 13.3 0.7 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DivIC PF04977.10 EIE85834.1 - 0.035 13.5 1.6 0.064 12.7 0.6 1.8 1 1 0 1 1 1 0 Septum formation initiator Baculo_PEP_C PF04513.7 EIE85834.1 - 0.038 13.8 7.4 0.06 13.1 5.1 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus PilJ PF13675.1 EIE85834.1 - 0.042 14.1 1.1 0.068 13.4 0.7 1.3 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term HOOK PF05622.7 EIE85834.1 - 0.049 11.4 0.4 0.063 11.0 0.3 1.0 1 0 0 1 1 1 0 HOOK protein Lzipper-MIP1 PF14389.1 EIE85834.1 - 0.052 13.6 0.2 2.3 8.4 0.0 2.3 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 FlxA PF14282.1 EIE85834.1 - 0.054 13.4 2.0 0.083 12.8 1.4 1.3 1 0 0 1 1 1 0 FlxA-like protein DUF869 PF05911.6 EIE85834.1 - 0.066 11.4 3.1 0.082 11.1 2.1 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) Cluap1 PF10234.4 EIE85834.1 - 0.069 12.3 0.6 0.1 11.8 0.4 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 bZIP_2 PF07716.10 EIE85834.1 - 0.082 12.7 3.2 2.4 8.0 0.1 2.6 1 1 1 2 2 2 0 Basic region leucine zipper DivIVA PF05103.8 EIE85834.1 - 0.1 12.6 2.1 0.18 11.8 0.1 2.1 1 1 1 2 2 2 0 DivIVA protein DUF2205 PF10224.4 EIE85834.1 - 0.11 12.0 1.7 0.19 11.2 1.2 1.3 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) DUF342 PF03961.8 EIE85834.1 - 0.12 10.7 0.3 0.17 10.2 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF4200 PF13863.1 EIE85834.1 - 0.13 12.1 0.3 0.24 11.3 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) bZIP_1 PF00170.16 EIE85834.1 - 0.16 11.9 1.8 0.53 10.2 0.6 2.3 1 1 1 2 2 2 0 bZIP transcription factor Mto2_bdg PF12808.2 EIE85834.1 - 0.21 11.7 0.3 0.21 11.7 0.2 2.0 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region SIS PF01380.17 EIE85835.1 - 0.069 12.7 0.1 0.1 12.2 0.1 1.2 1 0 0 1 1 1 0 SIS domain DDE_Tnp_IS1595 PF12762.2 EIE85837.1 - 6.9e-15 55.1 0.0 5.6e-09 35.9 0.0 2.7 1 1 1 2 2 2 2 ISXO2-like transposase domain Tom37_C PF11801.3 EIE85838.1 - 0.02 14.7 1.6 0.028 14.2 1.1 1.2 1 0 0 1 1 1 0 Tom37 C-terminal domain APC2 PF08672.6 EIE85838.1 - 0.084 13.1 0.0 0.68 10.2 0.0 2.3 2 0 0 2 2 2 0 Anaphase promoting complex (APC) subunit 2 DDE_3 PF13358.1 EIE85839.1 - 5e-17 62.0 0.0 7.2e-17 61.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE85839.1 - 8.2e-10 38.6 2.1 5e-09 36.0 0.9 2.3 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.1 EIE85839.1 - 0.00047 19.7 0.0 0.0012 18.4 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_11 PF08279.7 EIE85839.1 - 0.00068 19.2 0.0 0.0019 17.8 0.0 1.7 1 0 0 1 1 1 1 HTH domain HTH_IclR PF09339.5 EIE85839.1 - 0.00075 19.0 0.0 0.0015 18.0 0.0 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_7 PF02796.10 EIE85839.1 - 0.0032 17.2 0.2 0.061 13.1 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_32 PF13565.1 EIE85839.1 - 0.0039 17.9 0.8 3.2 8.6 0.0 2.9 2 0 0 2 2 2 1 Homeodomain-like domain HTH_38 PF13936.1 EIE85839.1 - 0.0073 15.8 0.0 0.016 14.7 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_36 PF13730.1 EIE85839.1 - 0.0082 16.2 0.4 0.25 11.5 0.0 2.9 3 0 0 3 3 3 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.7 EIE85839.1 - 0.011 15.1 0.0 0.03 13.7 0.0 1.7 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_AsnC-type PF13404.1 EIE85839.1 - 0.015 14.8 0.0 0.032 13.7 0.0 1.5 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_29 PF13551.1 EIE85839.1 - 0.017 15.2 0.1 0.11 12.6 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_4 PF13613.1 EIE85839.1 - 0.02 14.4 0.0 0.3 10.6 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix of DDE superfamily endonuclease UPF0122 PF04297.9 EIE85839.1 - 0.04 13.9 0.2 0.11 12.5 0.0 1.7 2 0 0 2 2 2 0 Putative helix-turn-helix protein, YlxM / p13 like Sigma70_r4 PF04545.11 EIE85839.1 - 0.041 13.2 0.0 0.087 12.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_24 PF13412.1 EIE85839.1 - 0.042 13.2 0.0 0.095 12.1 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_17 PF12728.2 EIE85839.1 - 0.049 13.9 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain GerE PF00196.14 EIE85839.1 - 0.096 12.0 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family DDE_3 PF13358.1 EIE85840.1 - 9.8e-15 54.5 0.0 1.8e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE85840.1 - 1.3e-13 50.8 0.4 3.4e-13 49.4 0.2 1.9 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 EIE85840.1 - 0.001 19.1 0.5 0.0022 18.0 0.4 1.6 1 0 0 1 1 1 1 Winged helix-turn helix DUF2110 PF09883.4 EIE85840.1 - 0.011 15.4 0.3 0.38 10.3 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2110) HTH_7 PF02796.10 EIE85840.1 - 0.026 14.3 0.1 0.9 9.4 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase SPOR PF05036.8 EIE85840.1 - 0.041 14.0 0.2 0.22 11.7 0.2 2.1 1 1 1 2 2 2 0 Sporulation related domain HTH_23 PF13384.1 EIE85840.1 - 0.093 12.4 0.3 1 9.0 0.0 2.4 2 0 0 2 2 2 0 Homeodomain-like domain Merozoite_SPAM PF07133.6 EIE85841.1 - 0.014 15.2 12.0 0.016 15.1 8.3 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) DUF1963 PF09234.5 EIE85841.1 - 0.044 14.0 2.6 0.045 13.9 1.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1963) DUF2890 PF11081.3 EIE85841.1 - 0.39 10.7 9.8 0.48 10.4 6.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Astro_capsid PF03115.9 EIE85841.1 - 2 6.5 3.8 2.1 6.4 2.6 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor rve PF00665.21 EIE85842.1 - 2.2e-26 92.3 0.0 4.8e-26 91.2 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 EIE85842.1 - 1.7e-05 24.2 0.0 6.8e-05 22.3 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.5 EIE85842.1 - 0.012 15.0 0.4 0.049 13.0 0.1 2.2 2 0 0 2 2 2 0 His(2)-Cys(2) zinc finger rve PF00665.21 EIE85845.1 - 1.9e-22 79.6 0.0 4.5e-22 78.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE85845.1 - 1.4e-15 57.2 0.1 2.8e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.12 EIE85845.1 - 8.2e-09 35.4 0.1 2.3e-08 34.0 0.1 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein Chromo PF00385.19 EIE85845.1 - 4.2e-08 32.7 0.1 9.7e-08 31.5 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 EIE85845.1 - 0.00047 19.5 1.6 0.0015 17.9 1.1 1.9 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger UBN2 PF14223.1 EIE85845.1 - 0.13 12.0 0.0 0.36 10.6 0.0 1.8 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type DDE_1 PF03184.14 EIE85846.1 - 7.9e-49 165.7 0.1 1.2e-48 165.1 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EIE85846.1 - 5.1e-05 22.9 0.0 0.00014 21.5 0.0 1.8 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.1 EIE85846.1 - 7.7e-05 22.4 0.0 0.00016 21.4 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease Chromo PF00385.19 EIE85847.1 - 2.5e-10 39.8 0.4 5.1e-10 38.8 0.3 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 EIE85847.1 - 0.0016 18.1 0.1 0.0035 16.9 0.1 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain SRP72 PF08492.7 EIE85847.1 - 0.037 14.3 4.0 0.073 13.4 2.7 1.5 1 0 0 1 1 1 0 SRP72 RNA-binding domain RVT_1 PF00078.22 EIE85848.1 - 6.9e-17 61.5 0.1 1.6e-16 60.3 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EIE85848.1 - 2.7e-10 40.3 0.0 7e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain rve PF00665.21 EIE85850.1 - 1.9e-22 79.6 0.0 4.7e-22 78.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE85850.1 - 1.5e-15 57.1 0.1 2.9e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.12 EIE85850.1 - 8.5e-09 35.3 0.1 2.4e-08 33.9 0.1 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein Chromo PF00385.19 EIE85850.1 - 4.4e-08 32.6 0.1 1e-07 31.5 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.1 EIE85850.1 - 5.3e-05 23.6 0.0 0.00012 22.4 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.5 EIE85850.1 - 0.00044 19.5 1.6 0.0015 17.8 1.1 2.0 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Asp_protease PF09668.5 EIE85850.1 - 0.0082 15.7 0.0 0.019 14.5 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EIE85850.1 - 0.023 14.4 0.0 0.058 13.2 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease UBN2 PF14223.1 EIE85850.1 - 0.14 11.9 0.0 0.37 10.5 0.0 1.8 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type rve PF00665.21 EIE85851.1 - 2.7e-19 69.4 0.0 6.4e-19 68.2 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE85851.1 - 3e-17 62.6 0.7 7e-17 61.4 0.2 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE85851.1 - 3.1e-14 52.3 1.1 7.6e-14 51.1 0.7 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RNase_H PF00075.19 EIE85851.1 - 0.033 14.5 0.0 0.16 12.3 0.0 2.2 2 0 0 2 2 2 0 RNase H F_actin_bind PF08919.5 EIE85851.1 - 0.049 13.3 0.1 0.25 11.0 0.0 2.2 2 0 0 2 2 2 0 F-actin binding DDE_3 PF13358.1 EIE85852.1 - 3.6e-12 46.2 0.2 4.7e-12 45.8 0.2 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Pkinase PF00069.20 EIE85855.1 - 1.5e-64 217.6 0.2 1.1e-35 123.0 0.0 5.4 3 2 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 EIE85855.1 - 6.8e-30 103.9 0.2 3.4e-12 45.9 0.0 4.7 4 1 1 5 5 5 4 Protein tyrosine kinase RWD PF05773.17 EIE85855.1 - 8.6e-19 67.5 0.2 2.7e-18 65.8 0.1 1.9 1 0 0 1 1 1 1 RWD domain tRNA-synt_His PF13393.1 EIE85855.1 - 3e-12 46.2 0.0 5.9e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon2 PF12745.2 EIE85855.1 - 1.1e-07 31.2 0.0 1.1e-07 31.2 0.0 3.4 3 1 0 3 3 3 1 Anticodon binding domain of tRNAs Kinase-like PF14531.1 EIE85855.1 - 0.0011 17.9 0.1 0.032 13.2 0.0 2.3 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EIE85855.1 - 0.0012 18.5 0.0 0.0027 17.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Cpn60_TCP1 PF00118.19 EIE85857.1 - 2.9e-24 85.5 0.1 4.6e-24 84.8 0.1 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PIP5K PF01504.13 EIE85857.1 - 1.3e-21 76.8 0.2 3.5e-21 75.4 0.2 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase FYVE PF01363.16 EIE85857.1 - 1.5e-09 37.5 2.8 1.5e-09 37.5 1.9 2.0 2 0 0 2 2 2 1 FYVE zinc finger Chitin_synth_2 PF03142.10 EIE85858.1 - 3.3e-236 784.7 0.4 5e-236 784.1 0.3 1.3 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 EIE85858.1 - 6.3e-89 298.8 2.1 7.9e-89 298.5 1.4 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Glyco_tranf_2_3 PF13641.1 EIE85858.1 - 6.6e-19 68.6 0.0 6.7e-16 58.7 0.0 2.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EIE85858.1 - 4.6e-17 62.3 0.3 4.6e-17 62.3 0.2 2.4 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Cyt-b5 PF00173.23 EIE85858.1 - 6.9e-16 57.8 0.0 9.7e-11 41.3 0.0 3.0 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glycos_transf_2 PF00535.21 EIE85858.1 - 1.2e-07 31.6 0.0 1.8e-05 24.5 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EIE85858.1 - 3.6e-05 23.1 0.0 0.00095 18.4 0.0 2.7 3 0 0 3 3 3 1 Glycosyl transferase family 21 Cu-oxidase_3 PF07732.10 EIE85859.1 - 2.8e-30 104.4 0.5 6.1e-30 103.3 0.2 1.7 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.17 EIE85859.1 - 3.2e-21 75.8 0.0 1.4e-20 73.8 0.0 1.9 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EIE85859.1 - 6.7e-14 51.5 0.3 1.5e-10 40.6 0.0 3.2 3 0 0 3 3 3 2 Multicopper oxidase Ank PF00023.25 EIE85860.1 - 8.8e-05 22.1 0.1 0.00027 20.5 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.1 EIE85860.1 - 0.00018 21.3 0.1 0.00072 19.5 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.2 EIE85860.1 - 0.00072 19.8 0.1 0.0011 19.2 0.1 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EIE85860.1 - 0.008 16.3 0.0 0.025 14.8 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 EIE85860.1 - 0.088 13.3 0.1 0.22 12.0 0.0 1.8 1 1 0 1 1 1 0 Ankyrin repeats (many copies) Bap31 PF05529.7 EIE85861.1 - 1.5e-36 125.7 21.8 6.8e-34 117.0 10.0 2.1 1 1 1 2 2 2 2 B-cell receptor-associated protein 31-like Phage_GP20 PF06810.6 EIE85861.1 - 0.0041 16.5 11.5 0.0041 16.5 7.9 1.5 2 0 0 2 2 2 1 Phage minor structural protein GP20 CHASE3 PF05227.8 EIE85861.1 - 0.051 13.2 5.8 0.097 12.3 4.0 1.4 1 0 0 1 1 1 0 CHASE3 domain NPV_P10 PF05531.7 EIE85861.1 - 0.12 12.6 1.6 0.19 11.9 1.0 1.4 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Reo_sigmaC PF04582.7 EIE85861.1 - 0.14 11.3 0.7 0.19 10.8 0.5 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein TPR_MLP1_2 PF07926.7 EIE85861.1 - 0.36 10.5 18.8 0.11 12.2 4.5 2.6 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein HALZ PF02183.13 EIE85861.1 - 0.6 9.8 7.7 2.4 7.9 2.1 2.6 1 1 1 2 2 2 0 Homeobox associated leucine zipper SlyX PF04102.7 EIE85861.1 - 0.66 10.3 7.5 14 6.0 4.1 2.9 1 1 1 2 2 2 0 SlyX DivIC PF04977.10 EIE85861.1 - 0.66 9.5 17.0 1 8.8 4.6 3.6 2 1 2 4 4 4 0 Septum formation initiator EMP24_GP25L PF01105.19 EIE85861.1 - 0.76 9.4 5.9 0.28 10.8 2.0 1.7 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD Tho2 PF11262.3 EIE85861.1 - 0.82 8.6 9.0 0.63 9.0 2.8 2.1 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 AAA_23 PF13476.1 EIE85861.1 - 1.4 9.2 12.2 2.2 8.5 8.4 1.2 1 0 0 1 1 1 0 AAA domain TMF_DNA_bd PF12329.3 EIE85861.1 - 1.6 8.5 14.9 2 8.2 8.2 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding GAS PF13851.1 EIE85861.1 - 1.9 7.6 20.4 0.059 12.5 9.9 1.5 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Seryl_tRNA_N PF02403.17 EIE85861.1 - 2.2 8.3 11.3 5.7 6.9 7.8 1.7 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF342 PF03961.8 EIE85861.1 - 2.5 6.4 10.8 1.7 6.9 6.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF342) FliD_N PF02465.13 EIE85861.1 - 2.6 8.4 7.3 1.8 8.9 3.5 1.8 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus MscL PF01741.13 EIE85861.1 - 4.9 7.3 7.3 0.75 9.9 0.7 2.4 1 1 1 2 2 2 0 Large-conductance mechanosensitive channel, MscL DUF4407 PF14362.1 EIE85861.1 - 7.1 5.4 10.6 0.99 8.3 3.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) UCH PF00443.24 EIE85862.1 - 2.9e-61 206.9 4.3 5.7e-61 205.9 3.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EIE85862.1 - 7.7e-26 91.1 2.1 7.7e-26 91.1 1.4 1.9 3 0 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 EIE85862.1 - 0.0027 17.0 5.6 1.1 8.5 3.9 3.2 1 1 0 1 1 1 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase PG_binding_1 PF01471.13 EIE85862.1 - 0.16 12.0 0.0 0.37 10.7 0.0 1.7 1 0 0 1 1 1 0 Putative peptidoglycan binding domain DUF2709 PF10915.3 EIE85864.1 - 0.028 13.4 0.0 0.028 13.4 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2709) Pkinase PF00069.20 EIE85865.1 - 7.7e-71 238.2 0.0 1.2e-70 237.5 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE85865.1 - 5.8e-29 100.9 0.0 9.3e-29 100.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE85865.1 - 2.6e-05 23.3 0.0 3.8e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 EIE85865.1 - 0.0028 17.0 0.0 0.0054 16.1 0.0 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL zf-CCHC_6 PF15288.1 EIE85866.1 - 0.0075 15.9 0.5 0.013 15.1 0.3 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-C2HC PF01530.13 EIE85866.1 - 0.053 13.2 4.7 0.14 11.8 3.2 1.8 1 1 0 1 1 1 0 Zinc finger, C2HC type DnaJ_CXXCXGXG PF00684.14 EIE85866.1 - 0.066 13.2 2.0 0.14 12.1 1.5 1.7 1 1 0 1 1 1 0 DnaJ central domain Ogr_Delta PF04606.7 EIE85866.1 - 0.48 10.1 3.2 1.2 8.8 2.2 1.9 1 1 0 1 1 1 0 Ogr/Delta-like zinc finger Pkinase PF00069.20 EIE85868.1 - 1.8e-07 30.5 0.0 2.8e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain DDE_3 PF13358.1 EIE85869.1 - 1.9e-20 73.0 0.0 4.1e-20 72.0 0.0 1.6 1 1 0 1 1 1 1 DDE superfamily endonuclease Dot_icm_IcmQ PF09475.5 EIE85869.1 - 0.078 12.2 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Dot/Icm secretion system protein (dot_icm_IcmQ) DUF899 PF05988.7 EIE85869.1 - 0.078 12.4 0.1 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF899) rve PF00665.21 EIE85869.1 - 0.079 13.0 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain zf-RVT PF13966.1 EIE85870.1 - 7.9e-10 38.9 2.1 1.8e-09 37.7 1.4 1.6 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase RVT_1 PF00078.22 EIE85870.1 - 0.037 13.3 0.0 0.083 12.2 0.0 1.7 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_1 PF03184.14 EIE85871.1 - 1.3e-22 79.9 2.1 2.6e-19 69.2 1.0 2.5 1 1 1 2 2 2 2 DDE superfamily endonuclease DDE_3 PF13358.1 EIE85871.1 - 0.0059 16.3 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Herpes_LMP1 PF05297.6 EIE85872.1 - 4.5 6.0 7.3 5.9 5.7 5.1 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) zf-CCHC PF00098.18 EIE85873.1 - 2.6e-06 27.0 9.0 6.5e-05 22.6 0.7 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 EIE85873.1 - 0.0029 17.2 2.7 0.68 9.6 0.2 2.5 2 0 0 2 2 2 2 Zinc knuckle RRM_6 PF14259.1 EIE85873.1 - 0.081 12.9 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EIE85873.1 - 0.13 11.8 0.0 1.5 8.5 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cmc1 PF08583.5 EIE85873.1 - 0.3 10.8 3.1 0.55 10.0 2.1 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like zf-CCHC_6 PF15288.1 EIE85873.1 - 1 9.0 9.3 0.24 11.0 1.3 2.6 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.1 EIE85873.1 - 1.1 8.8 5.0 1.1 8.7 0.8 2.3 1 1 1 2 2 2 0 Zinc knuckle RVT_1 PF00078.22 EIE85874.1 - 5.2e-14 52.1 0.0 7.4e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CCDC92 PF14916.1 EIE85874.1 - 0.067 12.7 0.7 0.27 10.8 0.0 2.1 2 0 0 2 2 2 0 Coiled-coil domain of unknown function DEAD PF00270.24 EIE85876.1 - 3.2e-46 156.9 0.0 1.2e-45 155.0 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase DBP10CT PF08147.7 EIE85876.1 - 5.5e-22 77.3 5.4 5.5e-22 77.3 3.7 3.1 3 0 0 3 3 3 1 DBP10CT (NUC160) domain Helicase_C PF00271.26 EIE85876.1 - 6.4e-21 73.9 0.2 1.7e-20 72.6 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Osteopontin PF00865.13 EIE85877.1 - 0.59 9.3 9.7 0.32 10.1 5.4 1.5 1 1 0 1 1 1 0 Osteopontin Grp1_Fun34_YaaH PF01184.14 EIE85878.1 - 1.5e-68 230.2 15.1 1.8e-68 230.0 10.5 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family CorA PF01544.13 EIE85878.1 - 0.049 12.6 2.3 0.071 12.1 1.6 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF3020 PF11223.3 EIE85879.1 - 1.4e-09 38.2 0.8 1.4e-09 38.2 0.5 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3020) zf-C2H2 PF00096.21 EIE85879.1 - 7.2e-06 26.0 0.2 2.3e-05 24.4 0.2 2.0 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIE85879.1 - 7.3e-06 25.9 2.5 1e-05 25.4 0.2 2.3 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EIE85879.1 - 0.044 13.9 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 EIE85879.1 - 0.15 12.3 0.3 0.15 12.3 0.2 2.0 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.1 EIE85879.1 - 0.15 12.3 3.2 0.22 11.8 0.3 2.4 2 0 0 2 2 2 0 Zinc-finger double domain FHA PF00498.21 EIE85880.1 - 2.5e-16 59.5 0.1 4.1e-16 58.8 0.1 1.4 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 EIE85880.1 - 9.9e-10 38.1 8.8 9.9e-10 38.1 6.1 1.6 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 EIE85880.1 - 2.8e-05 24.1 2.0 6.1e-05 23.0 1.4 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EIE85880.1 - 0.00028 20.4 7.7 0.00028 20.4 5.3 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIE85880.1 - 0.0019 17.8 8.1 0.0037 16.9 5.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EIE85880.1 - 0.0032 17.1 6.1 0.006 16.2 4.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EIE85880.1 - 0.011 15.5 1.6 0.02 14.7 1.1 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 EIE85880.1 - 0.021 14.8 10.1 0.021 14.8 7.0 1.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 EIE85880.1 - 0.032 13.9 4.2 0.054 13.1 2.9 1.4 1 0 0 1 1 1 0 PHD-finger Metallophos PF00149.23 EIE85881.1 - 1.7e-11 43.8 0.2 3e-11 43.1 0.1 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EIE85881.1 - 4.2e-08 33.1 0.1 7.9e-08 32.2 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF1191 PF06697.7 EIE85881.1 - 0.0046 15.8 0.0 0.0071 15.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) DUF4179 PF13786.1 EIE85881.1 - 0.025 14.8 0.1 0.042 14.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) Peptidase_M50 PF02163.17 EIE85881.1 - 0.026 13.5 0.0 0.026 13.5 0.0 1.1 1 0 0 1 1 1 0 Peptidase family M50 PIG-P PF08510.7 EIE85881.1 - 0.18 11.4 1.3 0.67 9.5 0.0 2.1 2 0 0 2 2 2 0 PIG-P NuiA PF07924.6 EIE85882.1 - 0.00022 21.1 1.5 0.0033 17.3 1.1 2.1 1 1 0 1 1 1 1 Nuclease A inhibitor-like protein Peptidase_S49_N PF08496.5 EIE85883.1 - 0.15 11.8 1.1 0.29 10.9 0.7 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Maf1 PF09174.5 EIE85885.1 - 1.2e-36 126.1 2.1 2.2e-24 86.2 0.0 2.2 1 1 1 2 2 2 2 Maf1 regulator Spc42p PF11544.3 EIE85886.1 - 7.1e-05 22.6 2.0 0.0001 22.1 1.4 1.3 1 0 0 1 1 1 1 Spindle pole body component Spc42p LAMTOR PF15454.1 EIE85886.1 - 0.018 15.2 1.4 0.028 14.7 1.0 1.2 1 0 0 1 1 1 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator Surfac_D-trimer PF09006.6 EIE85886.1 - 0.054 13.2 0.5 0.12 12.0 0.0 1.7 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation Sec2p PF06428.6 EIE85886.1 - 0.15 11.8 2.6 0.2 11.4 1.8 1.2 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p GrpE PF01025.14 EIE85886.1 - 1.1 8.7 4.7 1.4 8.3 3.2 1.1 1 0 0 1 1 1 0 GrpE Epimerase PF01370.16 EIE85887.1 - 4.1e-27 95.1 0.0 5.4e-27 94.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EIE85887.1 - 2.6e-12 46.2 0.0 3.9e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 EIE85887.1 - 8e-12 44.4 0.0 1.7e-11 43.3 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EIE85887.1 - 5.6e-08 32.0 0.1 4.2e-07 29.1 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EIE85887.1 - 1.1e-07 31.9 0.0 1.9e-07 31.2 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EIE85887.1 - 1.4e-05 25.0 0.0 3.4e-05 23.8 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EIE85887.1 - 4.6e-05 22.4 0.0 6.8e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 EIE85887.1 - 0.0026 17.4 0.0 0.0047 16.5 0.0 1.5 1 0 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 EIE85887.1 - 0.019 13.9 0.0 0.027 13.4 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase C_tripleX PF02363.14 EIE85888.1 - 1.4 9.1 4.6 15 5.9 0.2 2.4 2 0 0 2 2 2 0 Cysteine rich repeat C_tripleX PF02363.14 EIE85889.1 - 1.4 9.1 4.6 15 5.9 0.2 2.4 2 0 0 2 2 2 0 Cysteine rich repeat Aa_trans PF01490.13 EIE85890.1 - 3.1e-19 68.7 26.8 5.4e-19 67.9 18.6 1.4 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EIE85890.1 - 1.9e-07 30.2 2.7 1.9e-07 30.2 1.9 2.3 1 1 0 2 2 2 1 Tryptophan/tyrosine permease family Cytochrom_B_N PF00033.14 EIE85890.1 - 0.07 12.4 0.3 0.07 12.4 0.2 2.4 2 1 0 2 2 2 0 Cytochrome b(N-terminal)/b6/petB TehB PF03848.9 EIE85890.1 - 0.12 11.5 0.1 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB MRVI1 PF05781.7 EIE85890.1 - 0.29 9.4 1.7 9.6 4.4 0.1 2.2 2 0 0 2 2 2 0 MRVI1 protein PRKCSH-like PF12999.2 EIE85891.1 - 2.8e-58 196.3 6.3 2.8e-58 196.3 4.3 1.9 2 0 0 2 2 2 1 Glucosidase II beta subunit-like DUF2092 PF09865.4 EIE85891.1 - 0.019 14.0 0.1 0.039 13.0 0.0 1.5 1 0 0 1 1 1 0 Predicted periplasmic protein (DUF2092) GCFC PF07842.7 EIE85891.1 - 0.028 13.7 0.1 0.17 11.1 0.0 2.0 2 0 0 2 2 2 0 GC-rich sequence DNA-binding factor-like protein Ldl_recept_a PF00057.13 EIE85891.1 - 0.43 10.5 17.4 0.24 11.3 2.7 2.8 1 1 1 2 2 2 0 Low-density lipoprotein receptor domain class A DUF342 PF03961.8 EIE85891.1 - 1 7.6 15.5 0.37 9.1 0.7 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF342) DUF4140 PF13600.1 EIE85891.1 - 2.9 8.3 12.1 0.9 10.0 0.2 3.5 2 2 2 4 4 4 0 N-terminal domain of unknown function (DUF4140) RhoGAP PF00620.22 EIE85892.1 - 2.9e-37 127.6 0.5 7.1e-37 126.3 0.3 1.7 1 0 0 1 1 1 1 RhoGAP domain NOG1 PF06858.9 EIE85893.1 - 1.6e-29 101.5 0.4 3.7e-29 100.3 0.3 1.7 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.6 EIE85893.1 - 1.6e-28 98.1 1.0 4.1e-28 96.8 0.7 1.7 1 0 0 1 1 1 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.18 EIE85893.1 - 1.2e-18 67.0 0.0 2.9e-18 65.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EIE85893.1 - 4.9e-10 38.8 0.0 1.1e-09 37.7 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 EIE85893.1 - 1.4e-06 28.8 0.0 1.4e-05 25.6 0.0 2.7 3 0 0 3 3 3 1 Miro-like protein GTP_EFTU PF00009.22 EIE85893.1 - 0.0003 20.2 0.8 0.0077 15.6 0.5 2.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AIG1 PF04548.11 EIE85893.1 - 0.00046 19.3 0.0 0.001 18.2 0.0 1.6 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.18 EIE85893.1 - 0.0017 18.1 0.9 1.1 9.1 0.0 3.5 2 1 1 3 3 3 2 Dynamin family Gtr1_RagA PF04670.7 EIE85893.1 - 0.0025 17.0 0.0 0.0044 16.1 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF258 PF03193.11 EIE85893.1 - 0.0084 15.3 0.0 0.064 12.4 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function, DUF258 G-alpha PF00503.15 EIE85893.1 - 0.028 13.1 0.0 0.028 13.1 0.0 2.7 2 1 1 4 4 4 0 G-protein alpha subunit AAA_22 PF13401.1 EIE85893.1 - 0.037 14.1 0.0 0.2 11.7 0.0 2.3 1 1 0 1 1 1 0 AAA domain NUDIX PF00293.23 EIE85894.1 - 3.4e-10 39.7 0.0 4.1e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX PF00293.23 EIE85895.1 - 3.1e-06 26.8 0.0 4.2e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_2 PF13869.1 EIE85895.1 - 0.0022 17.3 0.5 0.0031 16.8 0.4 1.2 1 0 0 1 1 1 1 Nucleotide hydrolase FKBP_C PF00254.23 EIE85896.1 - 4.8e-07 29.7 0.0 1.1e-05 25.3 0.0 2.0 1 1 1 2 2 2 2 FKBP-type peptidyl-prolyl cis-trans isomerase Ricin_B_lectin PF00652.17 EIE85897.1 - 4.8e-64 213.9 3.2 6.3e-06 26.2 0.3 14.3 10 6 6 16 16 16 13 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 EIE85897.1 - 2.6e-32 111.3 16.1 7e-05 23.1 0.2 11.6 10 1 0 11 11 11 8 Ricin-type beta-trefoil lectin domain-like P22_AR_C PF10548.4 EIE85898.1 - 0.057 13.2 0.1 0.18 11.6 0.1 1.9 1 0 0 1 1 1 0 P22AR C-terminal domain Clat_adaptor_s PF01217.15 EIE85899.1 - 1.5e-11 44.1 0.2 1.7e-11 44.0 0.1 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DSHCT PF08148.7 EIE85900.1 - 2.1e-60 203.0 0.0 3.7e-60 202.2 0.0 1.4 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 EIE85900.1 - 1.3e-19 70.3 0.1 2.8e-19 69.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase rRNA_proc-arch PF13234.1 EIE85900.1 - 1.1e-07 31.3 0.0 2.2e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 rRNA-processing arch domain Helicase_C PF00271.26 EIE85900.1 - 4e-06 26.5 0.0 1.1e-05 25.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIE85900.1 - 0.0077 16.0 0.1 0.061 13.1 0.1 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF3516 PF12029.3 EIE85900.1 - 0.082 11.6 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3516) Aa_trans PF01490.13 EIE85902.1 - 5.9e-51 173.2 28.5 6.8e-51 173.0 19.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.1 EIE85902.1 - 3.8e-12 45.4 26.3 5.1e-12 45.0 18.2 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2759 PF10958.3 EIE85902.1 - 0.02 14.4 2.5 0.02 14.4 1.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2759) tRNA-synt_1d PF00750.14 EIE85903.1 - 9.3e-26 90.4 4.3 1.9e-25 89.4 3.0 1.5 1 1 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 EIE85903.1 - 4.2e-22 78.3 0.2 1.3e-21 76.7 0.0 2.0 2 0 0 2 2 2 1 DALR anticodon binding domain DBINO PF13892.1 EIE85903.1 - 0.0061 16.6 0.7 0.014 15.4 0.5 1.6 1 0 0 1 1 1 1 DNA-binding domain DUF914 PF06027.7 EIE85904.1 - 2.6e-32 111.9 6.9 3.1e-32 111.7 4.8 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) UAA PF08449.6 EIE85904.1 - 6e-05 22.1 5.1 7.2e-05 21.8 3.5 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 EIE85904.1 - 0.0015 18.5 13.1 0.0018 18.3 8.8 1.3 1 1 0 1 1 1 1 EamA-like transporter family TPT PF03151.11 EIE85904.1 - 0.0031 17.1 6.8 0.0032 17.1 4.0 1.5 1 1 0 1 1 1 1 Triose-phosphate Transporter family DUF3177 PF11375.3 EIE85904.1 - 0.0038 16.6 1.0 0.0038 16.6 0.7 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3177) EmrE PF13536.1 EIE85904.1 - 0.13 12.4 10.1 0.087 13.0 6.0 1.5 1 1 0 1 1 1 0 Multidrug resistance efflux transporter UPF0182 PF03699.8 EIE85904.1 - 3.3 5.5 5.1 3.5 5.4 3.6 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) adh_short PF00106.20 EIE85905.1 - 1.6e-19 70.4 0.0 2.7e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIE85905.1 - 2.6e-09 37.2 0.2 3.6e-09 36.7 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIE85905.1 - 2.9e-08 33.5 0.1 5e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EIE85905.1 - 0.0014 18.0 0.1 0.0021 17.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIE85905.1 - 0.0039 17.2 0.0 0.013 15.5 0.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding TBP PF00352.16 EIE85905.1 - 0.04 13.2 0.7 10 5.5 0.0 3.0 3 0 0 3 3 3 0 Transcription factor TFIID (or TATA-binding protein, TBP) DUF2048 PF09752.4 EIE85905.1 - 0.053 12.3 0.1 1.8 7.3 0.0 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2048) ABC_sub_bind PF04392.7 EIE85905.1 - 0.058 12.3 0.2 0.091 11.6 0.1 1.2 1 0 0 1 1 1 0 ABC transporter substrate binding protein QRPTase_C PF01729.14 EIE85905.1 - 0.069 12.6 0.1 0.098 12.1 0.0 1.2 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain zf-H2C2_2 PF13465.1 EIE85906.1 - 1.5e-14 53.4 18.8 6.3e-06 26.2 1.5 4.6 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.21 EIE85906.1 - 5.8e-09 35.7 27.7 2.4e-05 24.4 0.2 4.8 5 0 0 5 5 5 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIE85906.1 - 7.7e-09 35.2 22.2 0.00055 20.0 2.5 4.5 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EIE85906.1 - 8.1e-05 22.6 18.0 0.0084 16.2 0.9 4.1 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 EIE85906.1 - 0.00025 21.0 12.8 0.00086 19.3 0.6 3.4 2 1 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding GAGA PF09237.6 EIE85906.1 - 0.02 14.4 0.7 0.047 13.2 0.5 1.6 1 0 0 1 1 1 0 GAGA factor DUF4600 PF15372.1 EIE85906.1 - 0.069 13.3 0.1 0.12 12.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4600) zf-met PF12874.2 EIE85906.1 - 0.19 11.9 14.6 0.51 10.6 0.0 4.4 4 0 0 4 4 4 0 Zinc-finger of C2H2 type Kelch_4 PF13418.1 EIE85907.1 - 5.7e-21 74.0 0.1 3.4e-06 26.7 0.0 4.7 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_3 PF13415.1 EIE85907.1 - 3.4e-19 68.4 0.1 5.1e-06 26.4 0.0 5.5 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_6 PF13964.1 EIE85907.1 - 1.4e-18 66.2 0.1 0.00018 21.5 0.0 4.5 4 0 0 4 4 4 4 Kelch motif Kelch_5 PF13854.1 EIE85907.1 - 1.2e-17 63.4 0.1 4.4e-05 23.3 0.0 3.5 3 0 0 3 3 3 3 Kelch motif Kelch_1 PF01344.20 EIE85907.1 - 3e-17 61.8 0.4 0.00012 21.5 0.0 4.1 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.10 EIE85907.1 - 2.9e-13 48.9 1.0 0.00035 20.2 0.0 4.1 4 0 0 4 4 4 3 Kelch motif BTB PF00651.26 EIE85907.1 - 1e-11 44.7 0.3 2.2e-11 43.7 0.2 1.6 1 0 0 1 1 1 1 BTB/POZ domain RAG2 PF03089.9 EIE85907.1 - 0.00082 18.2 0.0 0.0024 16.6 0.0 1.7 1 1 1 2 2 2 1 Recombination activating protein 2 Sel1 PF08238.7 EIE85908.1 - 4.4e-15 55.7 6.3 4.8e-06 27.0 0.5 4.9 5 0 0 5 5 5 3 Sel1 repeat TPR_15 PF13429.1 EIE85908.1 - 4.6e-07 29.1 1.5 0.01 14.9 0.1 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 EIE85908.1 - 0.00065 19.2 4.6 0.3 10.7 0.0 4.0 2 1 2 4 4 4 1 TPR repeat TPR_14 PF13428.1 EIE85908.1 - 0.012 16.1 0.3 42 5.1 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 EIE85908.1 - 0.05 13.9 3.1 2.8 8.3 0.0 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_5 PF12688.2 EIE85908.1 - 0.068 13.2 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 Tetratrico peptide repeat DUF1680 PF07944.7 EIE85908.1 - 0.069 11.4 0.2 0.095 10.9 0.1 1.1 1 0 0 1 1 1 0 Putative glycosyl hydrolase of unknown function (DUF1680) SNAP PF14938.1 EIE85908.1 - 0.11 11.5 4.0 1.7 7.6 0.5 2.3 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP Apc3 PF12895.2 EIE85908.1 - 0.12 12.5 7.0 1.9 8.6 0.1 3.1 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 KAR9 PF08580.5 EIE85908.1 - 0.39 8.9 2.8 0.54 8.4 2.0 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Sod_Fe_N PF00081.17 EIE85909.1 - 1.5e-30 105.2 3.9 2.6e-30 104.5 2.7 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Sod_Fe_C PF02777.13 EIE85909.1 - 5.4e-23 80.8 0.0 1.2e-22 79.7 0.0 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Alk_phosphatase PF00245.15 EIE85910.1 - 1.2e-100 337.1 0.1 1.4e-100 336.9 0.1 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.13 EIE85910.1 - 0.0072 15.7 0.6 0.045 13.1 0.7 1.9 2 0 0 2 2 2 1 Metalloenzyme superfamily Chordopox_A35R PF05989.7 EIE85911.1 - 0.079 12.5 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Chordopoxvirus A35R protein p450 PF00067.17 EIE85913.1 - 7.7e-16 57.6 0.0 8.5e-16 57.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Polysacc_deac_1 PF01522.16 EIE85914.1 - 7.6e-21 74.0 0.1 1.5e-20 73.0 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase HMG_box PF00505.14 EIE85915.1 - 1.2e-17 63.9 2.0 2.2e-17 63.0 1.4 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EIE85915.1 - 2.1e-07 31.1 0.9 3.7e-07 30.4 0.6 1.4 1 0 0 1 1 1 1 HMG-box domain COX4 PF02936.9 EIE85915.1 - 0.0092 15.7 0.2 0.014 15.1 0.1 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DDE_3 PF13358.1 EIE85916.1 - 6.8e-05 22.6 0.0 0.00036 20.3 0.0 1.8 1 1 0 1 1 1 1 DDE superfamily endonuclease PH_9 PF15410.1 EIE85917.1 - 6.9e-43 145.6 0.1 1.7e-42 144.3 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain Sec7 PF01369.15 EIE85917.1 - 6.9e-41 140.0 2.7 1.1e-40 139.3 1.2 1.9 2 0 0 2 2 2 1 Sec7 domain PH PF00169.24 EIE85917.1 - 3.5e-05 23.9 0.1 0.00013 22.0 0.0 2.0 1 0 0 1 1 1 1 PH domain Ribosom_S12_S23 PF00164.20 EIE85918.1 - 3.2e-41 139.5 0.7 3.7e-41 139.3 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 MIF4G PF02854.14 EIE85920.1 - 1e-26 93.6 0.6 1.8e-26 92.8 0.4 1.3 1 0 0 1 1 1 1 MIF4G domain LMBR1 PF04791.11 EIE85920.1 - 0.14 10.7 6.6 0.19 10.2 4.6 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Pkinase PF00069.20 EIE85921.1 - 2.8e-71 239.6 0.2 2.8e-71 239.6 0.2 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE85921.1 - 9e-51 172.4 0.2 9e-51 172.4 0.1 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.23 EIE85921.1 - 1.6e-20 73.2 0.1 5.2e-20 71.6 0.0 2.0 2 0 0 2 2 1 1 P21-Rho-binding domain Kinase-like PF14531.1 EIE85921.1 - 3.5e-09 36.0 0.1 7.7e-08 31.6 0.0 2.3 1 1 1 2 2 2 1 Kinase-like CAP_N PF01213.14 EIE85921.1 - 6.3e-05 22.4 2.5 0.00012 21.5 1.7 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal Lipase_GDSL_3 PF14606.1 EIE85921.1 - 0.0045 16.7 0.2 0.61 9.7 0.0 2.9 3 0 0 3 3 3 1 GDSL-like Lipase/Acylhydrolase family APH PF01636.18 EIE85921.1 - 0.01 15.5 1.7 0.055 13.1 0.2 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EIE85921.1 - 0.038 12.8 0.5 0.068 11.9 0.4 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.9 EIE85921.1 - 0.061 12.3 1.9 0.097 11.7 0.2 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Phage_Gp23 PF10669.4 EIE85921.1 - 0.083 13.0 2.2 0.19 11.8 1.5 1.6 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Mito_fiss_reg PF05308.6 EIE85921.1 - 6.3 6.0 14.2 17 4.6 9.9 1.6 1 1 0 1 1 1 0 Mitochondrial fission regulator Phosphoesterase PF04185.9 EIE85922.1 - 1.3e-16 60.7 5.4 1.7e-16 60.3 0.5 2.0 1 1 1 2 2 2 2 Phosphoesterase family IlvN PF07991.7 EIE85923.1 - 1.6e-45 154.3 0.0 2.5e-45 153.7 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvC PF01450.14 EIE85923.1 - 3.9e-45 153.3 0.0 6.7e-45 152.5 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.10 EIE85923.1 - 0.0084 15.9 0.0 0.019 14.8 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EIE85923.1 - 0.011 16.1 0.0 0.027 14.9 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent AdoHcyase_NAD PF00670.16 EIE85923.1 - 0.083 12.7 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Profilin PF00235.14 EIE85924.1 - 2.9e-45 153.2 0.9 3.2e-45 153.1 0.6 1.0 1 0 0 1 1 1 1 Profilin Speriolin_N PF15058.1 EIE85926.1 - 0.019 14.9 0.9 0.025 14.4 0.6 1.3 1 0 0 1 1 1 0 Speriolin N terminus DUF4559 PF15112.1 EIE85926.1 - 0.18 10.9 7.1 0.27 10.3 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) Tropomyosin_1 PF12718.2 EIE85926.1 - 0.65 9.8 12.6 0.026 14.3 4.6 1.6 2 0 0 2 2 2 0 Tropomyosin like Retrotrans_gag PF03732.12 EIE85926.1 - 2.2 8.4 7.2 0.3 11.1 2.0 1.7 2 0 0 2 2 2 0 Retrotransposon gag protein Pkinase PF00069.20 EIE85928.1 - 2.2e-25 89.3 0.0 2.7e-25 89.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE85928.1 - 1.5e-11 43.8 0.0 2e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE85928.1 - 0.14 11.1 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Kinase-like DUF2154 PF09922.4 EIE85929.1 - 8.4e-05 22.2 2.0 0.0001 21.9 0.2 2.0 2 0 0 2 2 2 1 Cell wall-active antibiotics response protein (DUF2154) Cadherin PF00028.12 EIE85929.1 - 0.069 13.4 0.6 0.97 9.7 0.1 2.4 2 0 0 2 2 2 0 Cadherin domain PP1_inhibitor PF05361.7 EIE85929.1 - 0.085 12.5 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 PKC-activated protein phosphatase-1 inhibitor DDE_3 PF13358.1 EIE85934.1 - 4.3e-13 49.2 0.2 5.6e-13 48.8 0.2 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Phage_C PF12025.3 EIE85934.1 - 0.032 14.1 0.2 0.12 12.3 0.0 1.9 2 0 0 2 2 2 0 Phage protein C KH_1 PF00013.24 EIE85935.1 - 1.1e-22 79.3 0.2 5.5e-09 35.5 0.0 5.9 6 0 0 6 6 6 4 KH domain KH_3 PF13014.1 EIE85935.1 - 2.8e-20 71.5 2.5 1.6e-06 27.6 0.1 5.6 5 0 0 5 5 5 4 KH domain CTDII PF01556.13 EIE85936.1 - 1.2e-22 79.5 0.7 4.7e-18 64.8 0.0 2.4 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EIE85936.1 - 1.3e-14 53.9 21.1 2.1e-14 53.2 14.7 1.3 1 0 0 1 1 1 1 DnaJ central domain DnaJ PF00226.26 EIE85936.1 - 6.6e-08 32.1 0.0 1.2e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain HypA PF01155.14 EIE85936.1 - 0.0067 16.1 13.2 0.23 11.1 2.2 2.2 1 1 1 2 2 2 2 Hydrogenase expression/synthesis hypA family Cytochrom_c3_2 PF14537.1 EIE85936.1 - 0.099 12.9 7.3 0.24 11.7 5.1 1.7 1 0 0 1 1 1 0 Cytochrome c3 Cytochrome_C7 PF14522.1 EIE85936.1 - 1.9 8.1 10.5 6.7 6.4 7.3 1.9 1 1 0 1 1 1 0 Cytochrome c7 Cytochrom_CIII PF02085.11 EIE85936.1 - 6.7 6.8 9.0 24 5.0 6.2 1.8 1 1 1 2 2 2 0 Class III cytochrome C family TPR_16 PF13432.1 EIE85937.1 - 0.014 16.0 5.8 1.5 9.6 0.1 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Vps39_1 PF10366.4 EIE85937.1 - 0.089 12.8 2.5 0.13 12.2 0.4 2.2 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 TPR_11 PF13414.1 EIE85937.1 - 0.16 11.6 0.1 0.16 11.6 0.1 3.7 4 0 0 4 4 4 0 TPR repeat Flu_NS2 PF00601.14 EIE85937.1 - 0.22 11.7 2.0 6.2 7.0 0.0 3.2 2 1 1 3 3 3 0 Influenza non-structural protein (NS2) TPR_12 PF13424.1 EIE85937.1 - 0.33 10.9 13.4 1.2 9.0 1.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat RPN7 PF10602.4 EIE85938.1 - 2.2e-58 196.5 1.9 3e-58 196.0 1.3 1.2 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 EIE85938.1 - 1.1e-06 28.8 0.8 4.1e-06 27.0 0.2 2.3 2 0 0 2 2 2 1 PCI domain SAC3_GANP PF03399.11 EIE85938.1 - 0.00048 19.7 1.7 0.00099 18.7 1.2 1.5 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family TPR_7 PF13176.1 EIE85938.1 - 0.014 15.1 1.3 0.23 11.3 0.2 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF1672 PF07901.6 EIE85938.1 - 0.014 14.4 2.6 0.026 13.5 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1672) TPR_8 PF13181.1 EIE85938.1 - 0.016 14.9 2.0 0.071 12.9 1.4 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.12 EIE85938.1 - 0.029 14.2 1.6 0.3 11.0 1.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat UPF0172 PF03665.8 EIE85938.1 - 0.049 13.1 0.4 0.077 12.4 0.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) TPR_14 PF13428.1 EIE85938.1 - 0.085 13.5 0.0 1.6 9.5 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EIE85938.1 - 0.69 10.4 3.9 0.56 10.7 0.8 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat ABC_membrane PF00664.18 EIE85939.1 - 2.8e-82 276.2 40.4 2.7e-46 158.1 9.4 2.7 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.22 EIE85939.1 - 3.2e-55 186.1 0.0 4.8e-29 101.4 0.0 3.3 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.14 EIE85939.1 - 5.8e-11 42.0 0.0 7.9e-06 25.2 0.0 3.7 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EIE85939.1 - 1.5e-06 28.3 1.1 0.81 9.5 0.0 4.6 3 1 0 4 4 4 1 AAA domain MMR_HSR1 PF01926.18 EIE85939.1 - 2.1e-06 27.6 0.3 0.022 14.6 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 EIE85939.1 - 1.4e-05 24.3 0.7 0.0046 16.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 EIE85939.1 - 3.4e-05 23.8 4.9 0.069 13.1 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.1 EIE85939.1 - 5.5e-05 22.6 3.8 0.0066 15.9 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 EIE85939.1 - 0.00023 20.6 0.1 0.076 12.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 EIE85939.1 - 0.00071 19.4 1.8 1 9.1 0.0 2.7 2 0 0 2 2 2 2 Domain of unknown function DUF87 AAA_23 PF13476.1 EIE85939.1 - 0.00093 19.5 2.1 0.18 12.0 0.2 2.6 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EIE85939.1 - 0.0016 17.9 2.3 2 7.7 0.0 3.4 2 1 1 3 3 3 2 AAA-like domain Miro PF08477.8 EIE85939.1 - 0.002 18.6 2.3 0.61 10.5 0.1 2.9 2 0 0 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 EIE85939.1 - 0.0038 17.0 2.9 0.019 14.7 0.1 2.6 2 0 0 2 2 2 1 Dynamin family AAA_17 PF13207.1 EIE85939.1 - 0.0042 17.9 0.0 3.7 8.4 0.0 3.1 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 EIE85939.1 - 0.013 14.3 0.1 0.57 8.9 0.0 2.2 2 0 0 2 2 2 0 ArgK protein Zeta_toxin PF06414.7 EIE85939.1 - 0.013 14.6 1.0 3.7 6.6 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin MobB PF03205.9 EIE85939.1 - 0.039 13.6 1.4 3.4 7.3 0.1 2.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 EIE85939.1 - 0.046 13.2 2.2 6.5 6.2 0.1 3.4 3 0 0 3 3 3 0 AAA domain GTP_EFTU PF00009.22 EIE85939.1 - 0.096 12.1 0.7 1.2 8.5 0.0 2.6 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.13 EIE85939.1 - 0.12 11.7 0.1 8.5 5.7 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family ABC_ATPase PF09818.4 EIE85939.1 - 0.14 10.7 3.5 0.47 8.9 0.2 2.4 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_22 PF13401.1 EIE85939.1 - 0.53 10.4 6.2 5.1 7.2 0.0 3.7 3 1 0 3 3 2 0 AAA domain cobW PF02492.14 EIE85939.1 - 0.66 9.4 3.6 0.91 8.9 0.1 2.9 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Malate_synthase PF01274.17 EIE85941.1 - 2.5e-230 764.9 0.1 2.9e-230 764.7 0.0 1.0 1 0 0 1 1 1 1 Malate synthase HpcH_HpaI PF03328.9 EIE85941.1 - 0.0045 15.9 0.0 0.01 14.7 0.0 1.6 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Ribosomal_L37e PF01907.14 EIE85943.1 - 5.5e-26 90.1 12.6 1.1e-25 89.2 8.7 1.5 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.2 EIE85943.1 - 0.00027 20.6 2.9 0.00043 20.0 2.0 1.3 1 0 0 1 1 1 1 Double zinc ribbon SelR PF01641.13 EIE85943.1 - 0.0077 15.9 1.2 0.011 15.3 0.9 1.5 1 1 0 1 1 1 1 SelR domain HypA PF01155.14 EIE85943.1 - 0.029 14.0 1.0 0.041 13.5 0.7 1.2 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-RING_5 PF14634.1 EIE85943.1 - 0.034 13.8 4.0 0.052 13.2 2.8 1.3 1 0 0 1 1 1 0 zinc-RING finger domain C1_1 PF00130.17 EIE85943.1 - 0.046 13.4 3.6 0.084 12.6 2.5 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Ribosomal_S14 PF00253.16 EIE85943.1 - 0.16 11.3 6.9 0.83 9.0 0.1 2.5 1 1 1 2 2 2 0 Ribosomal protein S14p/S29e Ogr_Delta PF04606.7 EIE85943.1 - 0.21 11.2 3.3 0.66 9.6 0.2 2.3 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger GFA PF04828.9 EIE85943.1 - 0.35 10.8 4.3 1.6 8.7 2.5 2.1 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zf-ribbon_3 PF13248.1 EIE85943.1 - 0.48 9.6 4.1 2.8 7.2 3.0 1.9 1 1 1 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 EIE85943.1 - 0.61 9.6 5.3 6.9 6.2 3.7 2.1 1 1 1 2 2 2 0 zinc-ribbon domain zf-C3HC4_2 PF13923.1 EIE85943.1 - 0.62 10.1 5.1 0.98 9.4 3.5 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIE85943.1 - 0.9 9.2 5.1 1.4 8.6 3.5 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) YhfH PF14149.1 EIE85943.1 - 3.1 7.6 6.0 3.1 7.6 1.3 2.2 1 1 1 2 2 2 0 YhfH-like protein RNA_POL_M_15KD PF02150.11 EIE85943.1 - 4.3 7.1 5.9 32 4.3 4.2 2.0 1 1 0 1 1 1 0 RNA polymerases M/15 Kd subunit zf-HYPF PF07503.7 EIE85943.1 - 8.8 5.8 7.6 5.2 6.5 3.1 2.1 2 1 1 3 3 3 0 HypF finger Lyase_1 PF00206.15 EIE85944.1 - 1.3e-20 73.8 0.0 1.9e-20 73.2 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 EIE85944.1 - 2.9e-15 56.0 0.0 7.1e-15 54.7 0.0 1.7 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus DUF1331 PF07048.6 EIE85944.1 - 0.009 15.4 0.2 0.017 14.5 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1331) SHMT PF00464.14 EIE85945.1 - 1e-175 583.9 0.0 1.2e-175 583.7 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 EIE85945.1 - 5.7e-06 25.6 0.0 1.2e-05 24.6 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 EIE85945.1 - 1.9e-05 23.7 0.0 9.9e-05 21.4 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EIE85945.1 - 0.1 11.3 0.0 0.21 10.2 0.0 1.6 1 0 0 1 1 1 0 Aminotransferase class-V RVT_1 PF00078.22 EIE85946.1 - 0.0016 17.8 0.0 0.0033 16.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DivIC PF04977.10 EIE85947.1 - 0.0078 15.6 3.6 0.02 14.3 2.5 1.6 1 0 0 1 1 1 1 Septum formation initiator Lebercilin PF15619.1 EIE85947.1 - 0.013 14.9 2.6 0.013 14.9 1.8 1.5 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Herpes_BLRF2 PF05812.7 EIE85947.1 - 0.039 13.7 0.2 0.076 12.8 0.2 1.4 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein TMF_TATA_bd PF12325.3 EIE85947.1 - 0.079 12.6 0.2 0.17 11.6 0.1 1.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding SlyX PF04102.7 EIE85947.1 - 0.087 13.2 1.7 0.2 12.0 1.2 1.6 1 0 0 1 1 1 0 SlyX HALZ PF02183.13 EIE85947.1 - 0.13 12.0 0.1 0.36 10.5 0.1 1.8 1 0 0 1 1 1 0 Homeobox associated leucine zipper Cep57_CLD_2 PF14197.1 EIE85947.1 - 0.52 10.2 4.6 0.95 9.4 1.6 2.2 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 HEAT PF02985.17 EIE85948.1 - 2.4e-45 148.5 25.0 0.0017 18.2 0.1 14.2 15 0 0 15 15 15 11 HEAT repeat HEAT_2 PF13646.1 EIE85948.1 - 2.6e-32 110.9 9.1 1.3e-06 28.5 0.0 7.1 3 2 3 6 6 6 6 HEAT repeats HEAT_EZ PF13513.1 EIE85948.1 - 7.7e-11 42.1 13.1 0.00016 22.0 0.2 9.5 7 2 4 11 11 11 2 HEAT-like repeat Adaptin_N PF01602.15 EIE85948.1 - 3.4e-10 38.8 7.6 8e-06 24.4 0.0 3.5 2 1 1 4 4 4 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.2 EIE85948.1 - 1.5e-09 38.1 0.7 1.5 9.2 0.0 7.2 2 1 7 9 9 9 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 EIE85948.1 - 8.8e-05 21.9 1.3 2.4 7.4 0.0 4.5 1 1 4 5 5 5 1 CLASP N terminal DUF2435 PF10363.4 EIE85948.1 - 0.00086 19.1 4.6 3.1 7.7 0.0 4.5 4 1 1 5 5 5 2 Protein of unknown function (DUF2435) DNA_alkylation PF08713.6 EIE85948.1 - 0.0027 17.2 0.8 0.5 9.8 0.0 3.5 2 2 1 3 3 3 1 DNA alkylation repair enzyme M11L PF11099.3 EIE85948.1 - 0.038 13.7 0.3 12 5.6 0.0 3.1 3 0 0 3 3 3 0 Apoptosis regulator M11L like Cohesin_HEAT PF12765.2 EIE85948.1 - 0.13 12.2 1.4 0.76 9.7 0.0 3.0 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion CH PF00307.26 EIE85949.1 - 9.4e-05 22.4 0.0 0.00019 21.4 0.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain RasGAP_C PF03836.10 EIE85950.1 - 5.4e-32 110.4 4.0 5.4e-32 110.4 2.8 3.3 4 0 0 4 4 4 1 RasGAP C-terminus RasGAP PF00616.14 EIE85950.1 - 2e-30 105.9 0.2 6.9e-30 104.1 0.2 1.9 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase IQ PF00612.22 EIE85950.1 - 0.0022 17.4 13.4 0.12 12.0 0.1 4.8 5 0 0 5 5 5 2 IQ calmodulin-binding motif DUF4200 PF13863.1 EIE85950.1 - 0.26 11.2 12.1 0.11 12.4 0.7 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Sel1 PF08238.7 EIE85951.1 - 3.7e-51 170.4 22.1 2.6e-08 34.2 0.1 7.3 7 0 0 7 7 7 7 Sel1 repeat Yip1 PF04893.12 EIE85953.1 - 4.9e-09 35.9 12.5 7e-09 35.4 8.7 1.2 1 0 0 1 1 1 1 Yip1 domain AAA_2 PF07724.9 EIE85954.1 - 3.8e-44 150.6 0.0 5.6e-44 150.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 EIE85954.1 - 5e-16 59.1 0.0 1.1e-15 58.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 EIE85954.1 - 5.4e-09 35.8 0.1 1.2e-08 34.7 0.1 1.6 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 EIE85954.1 - 2.4e-07 30.5 0.0 5.9e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EIE85954.1 - 5.7e-06 26.4 0.2 0.00058 20.0 0.1 2.7 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EIE85954.1 - 8.8e-06 25.0 0.1 0.00065 18.9 0.0 2.2 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 EIE85954.1 - 1.7e-05 24.3 0.0 0.0069 15.8 0.0 2.5 3 0 0 3 3 2 1 Sigma-54 interaction domain IstB_IS21 PF01695.12 EIE85954.1 - 6.5e-05 22.4 0.0 0.00011 21.6 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_17 PF13207.1 EIE85954.1 - 0.00013 22.7 0.1 0.00045 21.0 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 EIE85954.1 - 0.00014 21.8 0.1 0.00051 20.0 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain Sigma54_activ_2 PF14532.1 EIE85954.1 - 0.00024 21.1 0.0 0.00061 19.8 0.0 1.7 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_14 PF13173.1 EIE85954.1 - 0.00035 20.4 0.0 0.00068 19.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EIE85954.1 - 0.00066 18.7 0.1 0.0019 17.2 0.1 1.6 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus T2SE PF00437.15 EIE85954.1 - 0.00079 18.4 0.0 0.0013 17.7 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_33 PF13671.1 EIE85954.1 - 0.0013 18.5 0.0 0.0026 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EIE85954.1 - 0.0017 18.6 0.0 0.0035 17.6 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_24 PF13479.1 EIE85954.1 - 0.0021 17.7 0.0 0.0033 17.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EIE85954.1 - 0.0022 17.4 0.0 0.0043 16.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain NACHT PF05729.7 EIE85954.1 - 0.0075 15.9 0.0 0.027 14.1 0.0 1.9 2 0 0 2 2 2 1 NACHT domain PhoH PF02562.11 EIE85954.1 - 0.013 14.7 0.0 0.024 13.8 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein MCM PF00493.18 EIE85954.1 - 0.013 14.3 0.1 0.032 13.0 0.1 1.6 1 1 0 1 1 1 0 MCM2/3/5 family DEAD PF00270.24 EIE85954.1 - 0.014 14.9 0.3 0.084 12.3 0.0 2.1 1 1 0 2 2 2 0 DEAD/DEAH box helicase AAA_19 PF13245.1 EIE85954.1 - 0.014 15.1 0.0 0.03 14.0 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_18 PF13238.1 EIE85954.1 - 0.026 14.8 0.0 0.064 13.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EIE85954.1 - 0.027 14.8 0.0 0.063 13.5 0.0 1.4 1 1 0 1 1 1 0 AAA domain ResIII PF04851.10 EIE85954.1 - 0.029 14.2 0.0 0.072 12.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit UPF0079 PF02367.12 EIE85954.1 - 0.038 13.6 0.0 0.075 12.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 SRPRB PF09439.5 EIE85954.1 - 0.065 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit TIP49 PF06068.8 EIE85954.1 - 0.075 11.7 0.0 0.13 10.9 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus AAA_3 PF07726.6 EIE85954.1 - 0.092 12.3 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EIE85954.1 - 0.11 12.6 0.0 0.24 11.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_28 PF13521.1 EIE85954.1 - 0.12 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 EIE85954.1 - 0.12 11.8 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation p450 PF00067.17 EIE85958.1 - 1.4e-78 264.5 0.1 1.9e-78 264.0 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIE85960.1 - 4.6e-74 249.5 0.5 3.4e-68 230.2 0.1 2.1 1 1 0 2 2 2 2 Cytochrome P450 DXP_synthase_N PF13292.1 EIE85960.1 - 0.092 11.6 0.0 0.18 10.7 0.0 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase zf-CCHC PF00098.18 EIE85961.1 - 0.00043 20.0 1.9 0.00043 20.0 1.3 1.9 2 0 0 2 2 2 1 Zinc knuckle p450 PF00067.17 EIE85964.1 - 1.6e-58 198.3 0.5 1.9e-58 198.1 0.3 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF915 PF06028.6 EIE85964.1 - 0.072 12.1 0.0 0.26 10.3 0.0 1.7 1 1 1 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) RVT_1 PF00078.22 EIE85966.1 - 9.9e-35 119.8 0.0 2.6e-34 118.4 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EIE85966.1 - 6.2e-07 29.0 0.0 3.4e-06 26.6 0.0 2.3 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EIE85966.1 - 5.2e-06 26.5 0.5 1.2e-05 25.3 0.1 1.7 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family zf-RVT PF13966.1 EIE85966.1 - 0.046 14.0 5.1 0.14 12.4 3.5 1.9 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase DDE_3 PF13358.1 EIE85967.1 - 8.9e-05 22.2 0.0 0.00015 21.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease GlutR_dimer PF00745.15 EIE85968.1 - 0.093 12.6 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, dimerisation domain p450 PF00067.17 EIE85970.1 - 1.8e-82 277.3 0.0 2.4e-82 276.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HD_2 PF12917.2 EIE85972.1 - 0.069 12.9 0.0 0.07 12.9 0.0 1.1 1 0 0 1 1 1 0 HD containing hydrolase-like enzyme DUF2418 PF10332.4 EIE85974.1 - 8.4 6.7 6.8 2.1 8.7 0.4 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2418) p450 PF00067.17 EIE85975.1 - 4.7e-75 252.8 1.0 2.2e-69 234.1 0.1 2.1 1 1 1 2 2 2 2 Cytochrome P450 Ribosomal_L11_N PF03946.9 EIE85976.1 - 2.2e-18 65.4 0.1 4.6e-18 64.4 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 EIE85976.1 - 1.7e-12 47.2 0.1 2.9e-12 46.5 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain IF2_N PF04760.10 EIE85976.1 - 0.055 13.1 0.1 0.4 10.3 0.0 2.3 1 1 1 2 2 2 0 Translation initiation factor IF-2, N-terminal region ADH_N PF08240.7 EIE85977.1 - 1e-05 25.2 0.1 0.00011 21.9 0.0 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Pyr_redox PF00070.22 EIE85977.1 - 0.1 12.9 0.1 0.39 11.1 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Sugar_tr PF00083.19 EIE85978.1 - 9.2e-98 327.7 18.9 1.1e-97 327.5 13.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIE85978.1 - 1.7e-26 92.7 57.1 7.6e-22 77.4 20.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EIE85978.1 - 4.5e-05 21.8 4.7 4.5e-05 21.8 3.2 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 EIE85978.1 - 0.0019 17.9 6.1 0.47 10.2 0.0 3.9 3 0 0 3 3 3 2 MFS_1 like family DUF1228 PF06779.9 EIE85978.1 - 0.036 14.0 11.7 0.19 11.7 0.1 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF1228) Gly-zipper_YMGG PF13441.1 EIE85978.1 - 0.13 11.8 3.5 0.43 10.1 2.4 1.9 1 0 0 1 1 1 0 YMGG-like Gly-zipper ERG4_ERG24 PF01222.12 EIE85979.1 - 2.8e-132 441.3 18.0 3.1e-132 441.1 12.5 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family PEMT PF04191.8 EIE85979.1 - 0.015 15.3 0.0 0.015 15.3 0.0 3.7 3 1 0 3 3 3 0 Phospholipid methyltransferase Arrestin_N PF00339.24 EIE85980.1 - 2.3e-08 34.0 0.1 5.1e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EIE85980.1 - 1.1e-07 31.9 0.1 7.9e-07 29.2 0.0 2.3 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.2 EIE85980.1 - 0.0049 16.3 0.0 0.011 15.2 0.0 1.5 2 0 0 2 2 2 1 Arrestin_N terminal like Collagen PF01391.13 EIE85981.1 - 3.6e-14 52.0 46.4 1.1e+03 -0.9 32.1 3.4 1 1 0 1 1 1 0 Collagen triple helix repeat (20 copies) Nuc_H_symport PF03825.11 EIE85981.1 - 0.33 9.6 0.2 0.42 9.3 0.2 1.1 1 0 0 1 1 1 0 Nucleoside H+ symporter Daxx PF03344.10 EIE85981.1 - 3.1 6.1 12.7 4.7 5.5 8.8 1.2 1 0 0 1 1 1 0 Daxx Family DUF2392 PF10288.4 EIE85982.1 - 0.011 16.0 0.4 0.018 15.3 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2392) UBA_e1_C PF09358.5 EIE85982.1 - 0.059 13.5 4.0 0.089 12.9 2.7 1.4 1 1 0 1 1 1 0 Ubiquitin-activating enzyme e1 C-terminal domain DUF663 PF04950.7 EIE85982.1 - 0.07 12.0 10.2 0.037 12.9 4.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF663) LMBR1 PF04791.11 EIE85982.1 - 0.091 11.3 2.9 0.11 11.0 2.0 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4110 PF13422.1 EIE85982.1 - 0.16 11.8 8.1 0.076 12.8 3.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4110) OmpH PF03938.9 EIE85982.1 - 1.3 8.9 12.2 2 8.3 8.4 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Dfp1_Him1_M PF08630.5 EIE85982.1 - 1.7 8.4 6.7 1.1 9.0 3.4 1.6 1 1 1 2 2 2 0 Dfp1/Him1, central region DDHD PF02862.12 EIE85982.1 - 5.2 6.8 7.3 6.5 6.4 5.1 1.1 1 0 0 1 1 1 0 DDHD domain CDI PF02234.14 EIE85982.1 - 8.9 6.2 7.3 5.5 6.8 0.2 2.8 3 0 0 3 3 3 0 Cyclin-dependent kinase inhibitor E1-E2_ATPase PF00122.15 EIE85983.1 - 7.4e-57 192.0 3.3 1.5e-56 190.9 2.3 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EIE85983.1 - 8.4e-45 152.5 5.4 8.4e-45 152.5 3.7 3.2 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EIE85983.1 - 7.9e-36 124.4 0.0 1e-34 120.8 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EIE85983.1 - 2.4e-22 78.6 0.0 5.2e-22 77.6 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EIE85983.1 - 1.2e-15 58.2 0.0 4.6e-15 56.2 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EIE85983.1 - 3.5e-15 55.2 0.0 7.9e-15 54.0 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EIE85983.1 - 2e-05 24.3 4.5 0.00017 21.2 0.2 2.8 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase MARVEL PF01284.18 EIE85983.1 - 0.38 10.5 15.5 1.4 8.7 2.5 4.0 4 0 0 4 4 4 0 Membrane-associating domain DUF2207 PF09972.4 EIE85983.1 - 6.1 5.3 8.0 0.86 8.1 0.0 2.8 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) DUF4203 PF13886.1 EIE85984.1 - 2.1e-20 73.0 32.9 2.6e-20 72.7 22.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) DUF4131 PF13567.1 EIE85984.1 - 6.5 6.1 21.5 0.7 9.2 0.2 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4131) Thioredoxin PF00085.15 EIE85985.1 - 1.5e-35 121.0 0.1 4.8e-26 90.4 0.1 3.6 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_2 PF13098.1 EIE85985.1 - 7.3e-10 39.0 1.0 7.8e-06 26.0 0.4 4.0 2 2 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EIE85985.1 - 1.7e-09 37.6 2.9 0.00019 21.4 0.0 4.9 2 1 2 4 4 4 2 Thioredoxin-like HyaE PF07449.6 EIE85985.1 - 0.0051 16.6 0.0 1.7 8.5 0.0 3.3 3 1 0 3 3 3 1 Hydrogenase-1 expression protein HyaE Thioredoxin_7 PF13899.1 EIE85985.1 - 0.02 14.9 0.1 0.21 11.6 0.0 2.5 2 0 0 2 2 2 0 Thioredoxin-like Thioredoxin_3 PF13192.1 EIE85985.1 - 0.066 13.0 0.1 6.1 6.7 0.0 2.6 2 1 0 2 2 2 0 Thioredoxin domain Mcp5_PH PF12814.2 EIE85986.1 - 1e-16 60.9 0.8 1.6e-16 60.2 0.6 1.3 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology HMG_box_5 PF14887.1 EIE85986.1 - 0.019 14.7 0.0 0.035 13.8 0.0 1.3 1 0 0 1 1 1 0 HMG (high mobility group) box 5 Pex24p PF06398.6 EIE85987.1 - 0.0025 16.6 0.1 0.0025 16.6 0.0 1.0 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin MCM PF00493.18 EIE85988.1 - 1.3e-133 444.9 0.5 1.6e-133 444.5 0.3 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EIE85988.1 - 5.7e-24 84.9 2.2 6e-24 84.8 0.5 1.8 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EIE85988.1 - 1.4e-05 24.3 0.0 0.00058 19.0 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EIE85988.1 - 9.2e-05 22.1 0.0 0.00041 20.0 0.0 2.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EIE85988.1 - 0.00045 19.8 0.1 0.0018 17.8 0.0 2.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase_2 PF13335.1 EIE85988.1 - 0.025 14.9 0.2 0.076 13.4 0.2 1.8 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 EIE85988.1 - 0.086 12.3 0.1 1.4 8.3 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain Ribosomal_L22 PF00237.14 EIE85989.1 - 5.8e-34 116.1 0.1 8.3e-34 115.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Phytochelatin PF05023.9 EIE85990.1 - 1e-53 181.4 0.1 1.2e-53 181.2 0.0 1.0 1 0 0 1 1 1 1 Phytochelatin synthase Velvet PF11754.3 EIE85991.1 - 4.5e-44 150.4 0.0 1e-43 149.3 0.0 1.6 1 1 0 1 1 1 1 Velvet factor TMF_TATA_bd PF12325.3 EIE85992.1 - 0.0097 15.6 0.3 0.0097 15.6 0.2 2.1 2 1 1 3 3 3 1 TATA element modulatory factor 1 TATA binding SOG2 PF10428.4 EIE85992.1 - 0.079 11.6 12.0 0.095 11.3 8.3 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Ndc1_Nup PF09531.5 EIE85992.1 - 3.9 5.7 10.0 4.7 5.5 6.9 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF1471 PF07338.8 EIE85993.1 - 0.18 11.4 2.7 1.6 8.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1471) zf-RVT PF13966.1 EIE85994.1 - 0.0019 18.4 1.2 0.0043 17.3 0.8 1.7 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase p450 PF00067.17 EIE85995.1 - 1.3e-71 241.5 1.0 7.3e-66 222.5 0.2 2.0 1 1 1 2 2 2 2 Cytochrome P450 Zip PF02535.17 EIE85996.1 - 4.5e-41 140.8 12.0 5.1e-41 140.7 8.3 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter CemA PF03040.9 EIE85996.1 - 0.018 14.6 0.1 0.036 13.6 0.1 1.5 1 1 0 1 1 1 0 CemA family DUF4271 PF14093.1 EIE85996.1 - 0.11 12.1 4.2 0.22 11.1 1.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4271) Phage_C PF12025.3 EIE85997.1 - 0.02 14.8 0.0 0.03 14.2 0.0 1.2 1 0 0 1 1 1 0 Phage protein C SSV1_ORF_D-335 PF07935.6 EIE86000.1 - 0.039 13.6 0.1 0.063 13.0 0.0 1.5 1 0 0 1 1 1 0 ORF D-335-like protein Leo1 PF04004.8 EIE86002.1 - 5.4e-44 149.9 4.5 5.9e-44 149.7 0.0 2.6 2 0 0 2 2 2 1 Leo1-like protein SNF2_N PF00176.18 EIE86003.1 - 3.9e-27 94.8 0.0 7.1e-27 93.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EIE86003.1 - 6.7e-12 45.1 0.0 1.5e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_14 PF13173.1 EIE86003.1 - 0.012 15.5 0.0 0.058 13.2 0.0 2.2 1 0 0 1 1 1 0 AAA domain Ser_hydrolase PF06821.8 EIE86003.1 - 0.031 13.9 0.1 0.055 13.0 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase MFS_1 PF07690.11 EIE86004.1 - 1e-29 103.4 62.6 3.4e-25 88.5 19.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EIE86004.1 - 1.4e-10 40.2 12.4 1.4e-10 40.2 8.6 2.8 1 1 2 3 3 3 2 MFS/sugar transport protein Sugar_tr PF00083.19 EIE86004.1 - 0.046 12.2 35.1 0.17 10.3 9.1 2.4 2 0 0 2 2 2 0 Sugar (and other) transporter Vsr PF03852.10 EIE86005.1 - 0.029 14.0 0.0 0.073 12.7 0.0 1.7 1 0 0 1 1 1 0 DNA mismatch endonuclease Vsr HTH_Tnp_Tc3_2 PF01498.13 EIE86005.1 - 0.04 13.9 0.2 1.2 9.2 0.0 3.0 3 0 0 3 3 3 0 Transposase Phage_integrase PF00589.17 EIE86006.1 - 0.0014 18.2 0.0 0.0029 17.2 0.0 1.6 1 1 0 1 1 1 1 Phage integrase family Phage_int_SAM_4 PF13495.1 EIE86006.1 - 0.097 13.0 0.3 0.38 11.1 0.1 2.0 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain RNase_H PF00075.19 EIE86007.1 - 1.1e-05 25.7 0.1 2e-05 24.9 0.1 1.4 1 0 0 1 1 1 1 RNase H DNA_pol_viral_C PF00336.13 EIE86007.1 - 0.0022 17.2 0.1 0.0031 16.8 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase (viral) C-terminal domain RVT_3 PF13456.1 EIE86007.1 - 0.041 13.6 0.0 0.093 12.5 0.0 1.6 1 0 0 1 1 1 0 Reverse transcriptase-like DUF3177 PF11375.3 EIE86007.1 - 0.14 11.5 1.3 0.19 11.1 0.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3177) DDE_3 PF13358.1 EIE86008.1 - 0.0012 18.5 0.0 0.0012 18.5 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease RVT_1 PF00078.22 EIE86009.1 - 2.6e-19 69.4 0.0 5.2e-19 68.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_3 PF13358.1 EIE86010.1 - 9.4e-18 64.3 0.4 5e-17 61.9 0.0 2.3 3 0 0 3 3 3 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE86010.1 - 1.4e-09 37.8 1.0 2.9e-09 36.8 0.2 2.0 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 EIE86010.1 - 0.027 14.6 0.0 0.11 12.6 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn helix HTH_32 PF13565.1 EIE86010.1 - 0.027 15.2 0.2 0.94 10.3 0.0 3.2 3 1 0 3 3 3 0 Homeodomain-like domain Chromo PF00385.19 EIE86011.1 - 2.8e-09 36.4 0.3 5e-09 35.6 0.2 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo PF00385.19 EIE86012.1 - 5.9e-15 54.6 1.2 9.4e-15 54.0 0.8 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.21 EIE86013.1 - 4.1e-20 72.0 0.0 1.1e-19 70.6 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain RNase_H PF00075.19 EIE86013.1 - 0.033 14.5 0.0 0.078 13.3 0.0 1.6 1 0 0 1 1 1 0 RNase H Transposase_21 PF02992.9 EIE86015.1 - 5.7e-23 81.1 0.1 5.7e-23 81.1 0.1 1.6 2 0 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.1 EIE86015.1 - 3.8e-05 23.1 0.3 8.5e-05 22.0 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) HTH_Tnp_Tc3_2 PF01498.13 EIE86016.1 - 7.5e-20 70.7 4.6 1.7e-19 69.6 0.3 2.3 2 1 0 2 2 2 1 Transposase HTH_29 PF13551.1 EIE86016.1 - 1.2e-05 25.3 1.0 2.7e-05 24.2 0.7 1.6 1 1 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.1 EIE86016.1 - 0.00037 21.2 3.6 0.0018 19.0 0.9 2.8 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.1 EIE86016.1 - 0.00066 19.2 0.4 0.1 12.2 0.0 3.3 3 0 0 3 3 3 1 Homeodomain-like domain HTH_21 PF13276.1 EIE86016.1 - 0.0022 17.9 0.8 0.25 11.3 0.0 2.8 2 1 1 3 3 3 1 HTH-like domain FUR PF01475.14 EIE86016.1 - 0.11 12.4 0.0 5.9 6.8 0.0 2.3 2 0 0 2 2 2 0 Ferric uptake regulator family NUMOD3 PF07460.6 EIE86016.1 - 0.12 12.2 0.1 0.22 11.4 0.1 1.5 1 0 0 1 1 1 0 NUMOD3 motif (2 copies) rve PF00665.21 EIE86017.1 - 7.2e-18 64.8 0.0 2.8e-17 62.9 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 EIE86017.1 - 1.7e-14 53.7 0.7 4.6e-14 52.2 0.5 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE86017.1 - 1.4e-06 27.8 1.3 5.3e-06 26.0 0.7 2.2 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.1 EIE86017.1 - 0.00039 20.8 0.0 0.0024 18.3 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease Tudor-knot PF11717.3 EIE86017.1 - 0.019 14.6 0.7 0.051 13.2 0.5 1.7 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain YcgR_2 PF12945.2 EIE86017.1 - 0.02 14.7 0.0 0.4 10.6 0.0 2.6 2 0 0 2 2 2 0 Flagellar protein YcgR gag-asp_proteas PF13975.1 EIE86017.1 - 0.05 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DDE_3 PF13358.1 EIE86018.1 - 7.2e-15 55.0 0.0 2e-14 53.5 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE86018.1 - 3e-08 33.5 2.0 8e-08 32.2 1.4 1.8 1 0 0 1 1 1 1 Transposase HTH_Tnp_4 PF13613.1 EIE86018.1 - 0.0051 16.3 0.0 0.0097 15.4 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease FAM70 PF14967.1 EIE86018.1 - 0.035 13.3 0.0 0.053 12.7 0.0 1.2 1 0 0 1 1 1 0 FAM70 protein RecX PF02631.11 EIE86018.1 - 0.039 14.1 0.2 0.07 13.3 0.1 1.4 1 0 0 1 1 1 0 RecX family TPR_MLP1_2 PF07926.7 EIE86019.1 - 0.0001 22.0 0.3 0.00016 21.4 0.2 1.2 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein Phage_GP20 PF06810.6 EIE86019.1 - 0.00025 20.5 0.3 0.00035 20.0 0.2 1.2 1 0 0 1 1 1 1 Phage minor structural protein GP20 Med4 PF10018.4 EIE86019.1 - 0.00073 18.9 0.1 0.001 18.5 0.1 1.2 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 DUF972 PF06156.8 EIE86019.1 - 0.0076 16.5 0.6 0.012 15.9 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF972) DivIVA PF05103.8 EIE86019.1 - 0.015 15.3 0.2 0.024 14.6 0.1 1.4 1 0 0 1 1 1 0 DivIVA protein Cluap1 PF10234.4 EIE86019.1 - 0.017 14.3 0.2 0.025 13.8 0.2 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 DivIC PF04977.10 EIE86019.1 - 0.029 13.8 0.2 0.059 12.8 0.1 1.6 1 0 0 1 1 1 0 Septum formation initiator HALZ PF02183.13 EIE86019.1 - 0.036 13.7 1.5 0.095 12.4 1.1 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper Mito_fiss_reg PF05308.6 EIE86019.1 - 0.037 13.3 1.1 0.053 12.8 0.7 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator SlyX PF04102.7 EIE86019.1 - 0.039 14.3 0.4 0.11 12.8 0.3 1.8 1 0 0 1 1 1 0 SlyX Rogdi_lz PF10259.4 EIE86019.1 - 0.048 12.7 1.2 0.074 12.1 0.8 1.2 1 0 0 1 1 1 0 Rogdi leucine zipper containing protein MAD PF05557.8 EIE86019.1 - 0.058 11.4 0.8 0.089 10.8 0.6 1.2 1 0 0 1 1 1 0 Mitotic checkpoint protein Allexi_40kDa PF05549.6 EIE86019.1 - 0.062 12.5 1.1 0.086 12.1 0.8 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein Mod_r PF07200.8 EIE86019.1 - 0.07 13.0 0.2 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Baculo_PEP_C PF04513.7 EIE86019.1 - 0.078 12.8 8.9 0.14 11.9 6.2 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1875 PF08961.5 EIE86019.1 - 0.082 12.2 0.1 0.13 11.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1875) Reo_sigmaC PF04582.7 EIE86019.1 - 0.51 9.4 6.3 0.7 9.0 4.4 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF1192 PF06698.6 EIE86019.1 - 0.52 10.1 2.1 0.74 9.6 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) DDE_3 PF13358.1 EIE86021.1 - 7.4e-21 74.4 0.0 1.5e-20 73.4 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE86021.1 - 1.1e-15 57.4 1.9 2.8e-15 56.1 0.3 2.3 3 0 0 3 3 2 1 Transposase HTH_29 PF13551.1 EIE86021.1 - 2.7e-06 27.5 0.2 8.6e-06 25.8 0.2 1.9 2 0 0 2 2 1 1 Winged helix-turn helix HTH_38 PF13936.1 EIE86021.1 - 1.2e-05 24.7 0.1 3.3e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.1 EIE86021.1 - 7.6e-05 22.2 0.1 0.0028 17.2 0.0 2.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.1 EIE86021.1 - 8.5e-05 23.2 2.8 0.02 15.6 0.1 3.7 4 0 0 4 4 3 1 Homeodomain-like domain Sigma70_r4_2 PF08281.7 EIE86021.1 - 0.00054 19.3 0.6 0.024 14.0 0.0 3.2 4 0 0 4 4 4 1 Sigma-70, region 4 HTH_28 PF13518.1 EIE86021.1 - 0.0013 18.7 0.0 0.0056 16.6 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_21 PF13276.1 EIE86021.1 - 0.0014 18.6 0.1 0.13 12.2 0.0 2.8 3 0 0 3 3 3 1 HTH-like domain HTH_7 PF02796.10 EIE86021.1 - 0.0022 17.7 1.1 0.1 12.4 0.0 2.8 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase rve PF00665.21 EIE86021.1 - 0.0045 17.0 0.0 0.014 15.4 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain LacI PF00356.16 EIE86021.1 - 0.018 14.6 1.7 2.8 7.6 0.2 2.7 3 0 0 3 3 3 0 Bacterial regulatory proteins, lacI family HTH_Tnp_4 PF13613.1 EIE86021.1 - 0.022 14.2 0.1 0.057 12.9 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease CPSase_L_D3 PF02787.14 EIE86021.1 - 0.058 13.1 0.0 0.14 11.8 0.0 1.6 2 0 0 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain HTH_36 PF13730.1 EIE86021.1 - 0.074 13.1 0.4 4.1 7.6 0.0 2.9 3 0 0 3 3 2 0 Helix-turn-helix domain Sigma70_r4 PF04545.11 EIE86021.1 - 0.1 11.9 0.2 0.79 9.0 0.0 2.6 4 0 0 4 4 4 0 Sigma-70, region 4 HTH_Tnp_ISL3 PF13542.1 EIE86021.1 - 0.17 11.0 2.8 8.4 5.6 0.0 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 HTH_17 PF12728.2 EIE86021.1 - 0.2 11.9 2.4 15 5.9 0.1 3.2 3 0 0 3 3 3 0 Helix-turn-helix domain DDE_3 PF13358.1 EIE86023.1 - 3.9e-11 42.8 0.1 5.2e-11 42.4 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF3279 PF11682.3 EIE86023.1 - 0.12 11.9 0.1 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3279) Transposase_21 PF02992.9 EIE86024.1 - 1.4e-21 76.6 0.1 2.6e-21 75.7 0.1 1.5 1 0 0 1 1 1 1 Transposase family tnp2 LXG PF04740.7 EIE86024.1 - 0.037 13.8 0.9 0.058 13.1 0.1 1.7 2 0 0 2 2 2 0 LXG domain of WXG superfamily 3HCDH_N PF02737.13 EIE86024.1 - 0.088 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FdhE PF04216.7 EIE86025.1 - 0.045 13.4 0.4 0.067 12.8 0.3 1.2 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation DUF1203 PF06718.6 EIE86026.1 - 0.085 12.6 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1203) Pkinase PF00069.20 EIE86027.1 - 2.6e-32 112.0 0.4 2.9e-32 111.8 0.3 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE86027.1 - 9.7e-17 60.8 0.1 1.1e-16 60.7 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE86027.1 - 2.9e-05 23.2 0.0 3.1e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EIE86027.1 - 4.3e-05 22.6 0.2 5.4e-05 22.3 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIE86027.1 - 0.00036 20.3 0.8 0.00037 20.3 0.6 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EIE86027.1 - 0.048 12.9 0.0 0.069 12.4 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.17 EIE86027.1 - 0.065 12.5 0.2 0.083 12.2 0.1 1.1 1 0 0 1 1 1 0 RIO1 family NAS PF03059.11 EIE86028.1 - 3.9e-59 200.1 1.6 4.6e-59 199.8 1.1 1.0 1 0 0 1 1 1 1 Nicotianamine synthase protein Methyltransf_31 PF13847.1 EIE86028.1 - 3.1e-06 26.8 0.1 6.3e-05 22.6 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIE86028.1 - 0.014 15.9 0.0 0.023 15.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EIE86028.1 - 0.074 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain zf-RVT PF13966.1 EIE86029.1 - 4.2e-06 26.9 4.0 9.2e-06 25.8 2.8 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase HTH_Tnp_Tc3_2 PF01498.13 EIE86030.1 - 7.7e-13 48.3 0.9 1.2e-12 47.6 0.1 1.8 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 EIE86030.1 - 2.5e-06 27.6 0.4 4.4e-06 26.8 0.3 1.4 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EIE86030.1 - 0.00039 19.9 0.1 0.0017 17.9 0.0 2.0 2 0 0 2 2 2 1 Homeodomain-like domain HTH_7 PF02796.10 EIE86030.1 - 0.00085 19.1 0.5 0.047 13.5 0.1 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase DDE_3 PF13358.1 EIE86030.1 - 0.094 12.4 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 DDE superfamily endonuclease DDE_3 PF13358.1 EIE86031.1 - 4.8e-10 39.3 0.6 4.8e-10 39.3 0.4 1.4 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE86032.1 - 1.8e-10 40.7 0.9 3.5e-10 39.7 0.6 1.5 1 0 0 1 1 1 1 Transposase HTH_Tnp_4 PF13613.1 EIE86032.1 - 0.028 13.9 0.0 0.061 12.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease RVT_1 PF00078.22 EIE86033.1 - 1.1e-23 83.7 0.0 1.7e-23 83.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EIE86033.1 - 2e-05 24.1 0.0 7.3e-05 22.3 0.0 2.1 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase DinB_2 PF12867.2 EIE86033.1 - 0.041 14.2 0.2 0.1 12.9 0.1 1.6 1 0 0 1 1 1 0 DinB superfamily RVT_1 PF00078.22 EIE86034.1 - 1.9e-23 82.9 0.0 2.7e-23 82.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EIE86035.1 - 2.9e-16 59.1 0.0 4.9e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EIE86035.1 - 0.0022 17.9 7.6 0.032 14.1 5.3 2.2 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EIE86036.1 - 5.2e-13 48.6 0.0 1.2e-12 47.5 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RVT_1 PF00078.22 EIE86036.1 - 1.2e-07 31.2 0.0 2.3e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TPR_MLP1_2 PF07926.7 EIE86037.1 - 0.00012 21.8 0.3 0.00019 21.1 0.2 1.2 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein Phage_GP20 PF06810.6 EIE86037.1 - 0.0002 20.8 0.1 0.0003 20.2 0.1 1.2 1 0 0 1 1 1 1 Phage minor structural protein GP20 SlyX PF04102.7 EIE86037.1 - 0.0051 17.1 0.2 0.012 15.9 0.2 1.6 1 0 0 1 1 1 1 SlyX Med4 PF10018.4 EIE86037.1 - 0.013 14.9 0.1 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF972 PF06156.8 EIE86037.1 - 0.014 15.7 0.3 0.022 15.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Cluap1 PF10234.4 EIE86037.1 - 0.021 14.0 0.2 0.03 13.5 0.2 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 HALZ PF02183.13 EIE86037.1 - 0.028 14.1 1.1 0.071 12.8 0.8 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper Rogdi_lz PF10259.4 EIE86037.1 - 0.034 13.2 1.1 0.055 12.5 0.8 1.3 1 0 0 1 1 1 0 Rogdi leucine zipper containing protein MAD PF05557.8 EIE86037.1 - 0.044 11.8 0.9 0.062 11.3 0.6 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein DivIVA PF05103.8 EIE86037.1 - 0.052 13.6 0.1 0.087 12.8 0.1 1.3 1 0 0 1 1 1 0 DivIVA protein DivIC PF04977.10 EIE86037.1 - 0.059 12.8 0.1 0.11 11.9 0.1 1.5 1 0 0 1 1 1 0 Septum formation initiator Baculo_PEP_C PF04513.7 EIE86037.1 - 0.1 12.4 8.7 0.17 11.6 6.0 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 EIE86037.1 - 0.13 11.3 2.8 0.19 10.8 1.9 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Birna_RdRp PF04197.7 EIE86037.1 - 0.14 10.1 0.7 0.19 9.7 0.5 1.1 1 0 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) DDE_3 PF13358.1 EIE86038.1 - 1.3e-07 31.4 0.4 1.3e-07 31.4 0.3 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4112 PF13430.1 EIE86039.1 - 2.2e-34 117.5 0.7 3e-34 117.1 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) MMtag PF10159.4 EIE86039.1 - 0.019 15.0 0.9 0.037 14.0 0.6 1.5 1 0 0 1 1 1 0 Kinase phosphorylation protein Pro_CA PF00484.14 EIE86040.1 - 7.5e-48 162.4 0.9 1.1e-47 161.8 0.6 1.2 1 0 0 1 1 1 1 Carbonic anhydrase WD40 PF00400.27 EIE86040.1 - 0.00011 21.9 3.0 0.058 13.3 0.0 3.8 5 0 0 5 5 5 2 WD domain, G-beta repeat adh_short PF00106.20 EIE86042.1 - 2.2e-06 27.7 2.6 3.5e-05 23.7 1.8 2.1 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 EIE86042.1 - 1.3e-05 24.7 0.1 0.00014 21.3 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EIE86042.1 - 0.017 14.0 0.0 0.023 13.5 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain TrbH PF07283.6 EIE86042.1 - 0.054 13.3 0.0 0.098 12.5 0.0 1.4 1 0 0 1 1 1 0 Conjugal transfer protein TrbH NmrA PF05368.8 EIE86042.1 - 0.14 11.3 0.2 0.22 10.7 0.1 1.4 1 0 0 1 1 1 0 NmrA-like family 3HCDH_N PF02737.13 EIE86042.1 - 0.16 11.5 0.3 0.37 10.4 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SRP54 PF00448.17 EIE86045.1 - 2.7e-49 167.3 0.0 5.2e-49 166.3 0.0 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.8 EIE86045.1 - 1.6e-45 155.7 15.9 2.9e-45 154.8 11.1 1.4 1 1 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal CbiA PF01656.18 EIE86045.1 - 4e-07 29.6 0.0 1.3e-06 28.0 0.0 1.8 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain SRP54_N PF02881.14 EIE86045.1 - 3.7e-06 26.9 0.6 7.2e-05 22.8 0.0 3.4 3 1 1 4 4 4 1 SRP54-type protein, helical bundle domain AAA_22 PF13401.1 EIE86045.1 - 0.0014 18.7 0.0 0.0069 16.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EIE86045.1 - 0.0014 18.6 0.0 0.005 16.8 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain ArgK PF03308.11 EIE86045.1 - 0.0015 17.3 0.0 0.0077 15.0 0.0 2.1 2 1 0 2 2 2 1 ArgK protein MobB PF03205.9 EIE86045.1 - 0.018 14.7 0.0 0.074 12.7 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Vac7 PF12751.2 EIE86045.1 - 0.038 12.8 2.3 0.058 12.2 1.6 1.2 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 Fer4_NifH PF00142.13 EIE86045.1 - 0.052 12.7 0.0 0.11 11.6 0.0 1.5 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_10 PF12846.2 EIE86045.1 - 0.073 12.5 0.0 0.073 12.5 0.0 2.0 2 1 0 2 2 1 0 AAA-like domain 3HCDH PF00725.17 EIE86045.1 - 0.098 13.0 0.1 0.48 10.8 0.0 2.2 2 0 0 2 2 1 0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Oxidored_FMN PF00724.15 EIE86046.1 - 3.4e-11 42.7 0.0 3.9e-11 42.5 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Acetyltransf_7 PF13508.1 EIE86047.1 - 3e-08 33.7 0.1 5.5e-08 32.8 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EIE86047.1 - 5.1e-08 32.8 0.0 7.5e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EIE86047.1 - 0.0043 17.1 0.0 0.015 15.4 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EIE86047.1 - 0.023 14.6 0.3 0.073 13.0 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 EIE86047.1 - 0.034 13.8 0.0 0.076 12.7 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein SynMuv_product PF06047.6 EIE86047.1 - 0.039 13.6 0.1 0.19 11.4 0.0 2.0 2 0 0 2 2 2 0 Ras-induced vulval development antagonist tRNA-synt_1d PF00750.14 EIE86048.1 - 9.5e-81 271.3 1.0 1.4e-80 270.8 0.7 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (R) Pyr_redox_2 PF07992.9 EIE86048.1 - 1.5e-43 148.9 0.4 3.5e-43 147.8 0.3 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EIE86048.1 - 1.3e-30 105.5 0.1 3.4e-30 104.3 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain DALR_1 PF05746.10 EIE86048.1 - 2.2e-22 79.2 0.0 4.7e-22 78.1 0.0 1.6 1 0 0 1 1 1 1 DALR anticodon binding domain Pyr_redox PF00070.22 EIE86048.1 - 1.7e-18 66.8 5.0 8.9e-17 61.2 0.1 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EIE86048.1 - 1.1e-12 48.4 0.2 9.2e-11 42.1 0.0 2.5 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EIE86048.1 - 6.2e-07 28.8 0.0 1.1e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.9 EIE86048.1 - 3.5e-05 23.2 0.3 0.0033 16.8 0.0 2.5 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HI0933_like PF03486.9 EIE86048.1 - 5.4e-05 21.8 3.9 0.11 10.9 0.5 3.7 3 1 1 4 4 4 2 HI0933-like protein K_oxygenase PF13434.1 EIE86048.1 - 9.6e-05 21.4 0.0 0.00044 19.2 0.0 1.9 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EIE86048.1 - 0.00069 19.5 5.1 0.0023 17.8 3.5 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Arg_tRNA_synt_N PF03485.11 EIE86048.1 - 0.00075 19.9 0.5 0.003 18.0 0.2 2.2 2 0 0 2 2 1 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1e PF01406.14 EIE86048.1 - 0.0016 17.6 0.0 0.0039 16.3 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain FAD_binding_2 PF00890.19 EIE86048.1 - 0.0017 17.2 7.7 0.0028 16.5 3.8 2.5 2 1 0 2 2 2 1 FAD binding domain DAO PF01266.19 EIE86048.1 - 0.0022 16.9 0.8 0.0022 16.9 0.6 3.2 4 0 0 4 4 4 1 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.14 EIE86048.1 - 0.0042 16.2 0.0 0.0042 16.2 0.0 2.5 3 0 0 3 3 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EIE86048.1 - 0.0062 16.1 2.6 0.1 12.1 0.0 3.1 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 EIE86048.1 - 0.029 14.0 0.1 0.029 14.0 0.0 2.1 2 0 0 2 2 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.12 EIE86048.1 - 0.053 12.6 4.7 0.049 12.7 0.6 2.5 2 0 0 2 2 2 0 Thi4 family NAD_binding_2 PF03446.10 EIE86048.1 - 0.061 13.1 0.9 0.93 9.3 0.2 2.9 2 1 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase GIDA PF01134.17 EIE86048.1 - 0.062 12.1 7.1 0.43 9.3 3.2 2.7 2 1 0 2 2 2 0 Glucose inhibited division protein A EABR PF12180.3 EIE86048.1 - 0.21 10.9 0.0 0.21 10.9 0.0 2.0 2 0 0 2 2 2 0 TSG101 and ALIX binding domain of CEP55 NAD_Gly3P_dh_N PF01210.18 EIE86048.1 - 0.38 10.4 2.8 0.4 10.4 0.0 2.3 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Syja_N PF02383.13 EIE86049.1 - 1.7e-96 322.7 1.5 2.3e-96 322.3 1.0 1.2 1 0 0 1 1 1 1 SacI homology domain DUF3043 PF11241.3 EIE86049.1 - 0.51 9.9 2.5 7.3 6.1 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) DUF4477 PF14780.1 EIE86050.1 - 0.0027 17.1 1.4 0.0046 16.3 1.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4477) SpoIIID PF12116.3 EIE86050.1 - 0.1 12.5 0.1 0.19 11.6 0.1 1.4 1 0 0 1 1 1 0 Stage III sporulation protein D DUF3469 PF11952.3 EIE86050.1 - 1.4 8.6 4.8 11 5.7 0.7 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3469) HTH_Tnp_Tc3_2 PF01498.13 EIE86051.1 - 1.5e-15 56.9 1.1 7e-15 54.8 0.1 2.3 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.1 EIE86051.1 - 1e-07 31.7 0.0 2e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 EIE86051.1 - 8.5e-07 29.1 0.1 2.7e-06 27.5 0.1 1.9 1 0 0 1 1 1 1 Winged helix-turn helix HTH_7 PF02796.10 EIE86051.1 - 8.8e-07 28.6 1.3 3.4e-05 23.5 0.4 2.7 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_23 PF13384.1 EIE86051.1 - 8.8e-07 28.3 0.1 4.7e-05 22.8 0.0 2.8 3 0 0 3 3 3 1 Homeodomain-like domain HTH_32 PF13565.1 EIE86051.1 - 0.00054 20.7 0.0 0.005 17.5 0.0 2.6 2 1 1 3 3 2 1 Homeodomain-like domain HTH_36 PF13730.1 EIE86051.1 - 0.0006 19.8 1.5 0.0061 16.6 0.4 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_28 PF13518.1 EIE86051.1 - 0.0017 18.3 0.0 0.093 12.7 0.0 3.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_33 PF13592.1 EIE86051.1 - 0.0018 17.7 0.1 0.0054 16.2 0.0 1.9 2 0 0 2 2 2 1 Winged helix-turn helix HTH_Tnp_ISL3 PF13542.1 EIE86051.1 - 0.0027 16.8 0.1 0.098 11.8 0.0 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_38 PF13936.1 EIE86051.1 - 0.0044 16.5 0.0 0.015 14.8 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_11 PF08279.7 EIE86051.1 - 0.0045 16.5 0.3 0.088 12.4 0.1 2.4 2 0 0 2 2 2 1 HTH domain HTH_24 PF13412.1 EIE86051.1 - 0.006 15.9 0.2 0.13 11.7 0.1 2.5 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_3 PF01381.17 EIE86051.1 - 0.015 15.1 0.7 0.1 12.4 0.2 2.1 2 0 0 2 2 2 0 Helix-turn-helix LacI PF00356.16 EIE86051.1 - 0.016 14.8 1.3 2 8.1 0.1 2.5 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family HTH_AsnC-type PF13404.1 EIE86051.1 - 0.02 14.4 0.0 0.043 13.3 0.0 1.5 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_21 PF13276.1 EIE86051.1 - 0.02 14.8 0.0 0.074 13.0 0.0 1.9 2 0 0 2 2 2 0 HTH-like domain Trp_repressor PF01371.14 EIE86051.1 - 0.032 14.1 0.2 0.088 12.7 0.1 1.7 1 0 0 1 1 1 0 Trp repressor protein GerE PF00196.14 EIE86051.1 - 0.033 13.4 1.3 0.059 12.6 0.1 1.9 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family HTH_22 PF13309.1 EIE86051.1 - 0.048 13.4 0.1 0.15 11.8 0.1 1.8 1 0 0 1 1 1 0 HTH domain Sigma54_DBD PF04552.8 EIE86051.1 - 0.079 12.4 1.8 0.28 10.6 0.1 2.4 3 0 0 3 3 2 0 Sigma-54, DNA binding domain GntR PF00392.16 EIE86051.1 - 0.086 12.2 0.1 4.4 6.8 0.0 2.5 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family TrmB PF01978.14 EIE86051.1 - 0.097 12.3 0.6 0.77 9.5 0.2 2.3 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB KorB PF08535.5 EIE86051.1 - 0.1 12.7 0.1 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 KorB domain Acetyltransf_2 PF00797.12 EIE86051.1 - 0.13 11.7 0.9 8.1 5.9 0.0 2.5 2 1 1 3 3 3 0 N-acetyltransferase HTH_Tnp_Tc3_2 PF01498.13 EIE86052.1 - 2.2e-11 43.6 0.7 3.5e-11 43.0 0.1 1.7 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 EIE86052.1 - 6.6e-06 26.2 0.1 1.2e-05 25.4 0.1 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EIE86052.1 - 0.00011 21.6 0.1 0.001 18.6 0.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_7 PF02796.10 EIE86052.1 - 0.0052 16.6 0.1 0.46 10.3 0.0 2.7 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase DDE_3 PF13358.1 EIE86052.1 - 0.0081 15.9 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_28 PF13518.1 EIE86052.1 - 0.073 13.0 0.2 0.4 10.7 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain Zn_Tnp_IS1 PF03811.8 EIE86053.1 - 0.0015 17.9 2.0 0.0034 16.8 1.4 1.6 1 0 0 1 1 1 1 InsA N-terminal domain CASP_C PF08172.7 EIE86053.1 - 0.002 17.1 0.8 0.003 16.6 0.5 1.2 1 0 0 1 1 1 1 CASP C terminal Phage_Integr_2 PF13009.1 EIE86053.1 - 0.0099 14.8 0.4 0.013 14.4 0.3 1.1 1 0 0 1 1 1 1 Putative phage integrase DUF3268 PF11672.3 EIE86053.1 - 0.014 15.4 0.6 0.037 14.1 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3268) Syntaphilin PF15290.1 EIE86053.1 - 0.016 14.7 3.5 0.022 14.2 2.4 1.2 1 0 0 1 1 1 0 Golgi-localised syntaxin-1-binding clamp Peptidase_C6 PF00851.13 EIE86053.1 - 0.018 13.6 0.3 0.022 13.3 0.2 1.2 1 0 0 1 1 1 0 Helper component proteinase FdhE PF04216.7 EIE86053.1 - 0.022 14.4 0.5 0.022 14.4 0.4 2.1 1 1 1 2 2 2 0 Protein involved in formate dehydrogenase formation zf-DNA_Pol PF08996.5 EIE86053.1 - 0.027 13.8 2.2 0.05 12.9 0.9 1.8 1 1 1 2 2 2 0 DNA Polymerase alpha zinc finger zf-SNAP50_C PF12251.3 EIE86053.1 - 0.074 12.4 0.9 0.14 11.5 0.6 1.4 1 0 0 1 1 1 0 snRNA-activating protein of 50kDa MW C terminal Mnd1 PF03962.10 EIE86053.1 - 0.077 12.6 0.1 0.14 11.8 0.1 1.3 1 0 0 1 1 1 0 Mnd1 family DUF4094 PF13334.1 EIE86053.1 - 0.081 13.3 0.5 0.24 11.8 0.2 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4094) DUF1664 PF07889.7 EIE86053.1 - 0.098 12.4 0.1 0.17 11.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) TF_Zn_Ribbon PF08271.7 EIE86053.1 - 0.1 11.9 0.5 0.19 11.1 0.4 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding DUF2296 PF10058.4 EIE86053.1 - 0.11 12.2 0.7 0.21 11.3 0.5 1.5 1 0 0 1 1 1 0 Predicted integral membrane metal-binding protein (DUF2296) zf-Dof PF02701.10 EIE86053.1 - 0.11 12.4 1.7 0.25 11.2 1.2 1.6 1 0 0 1 1 1 0 Dof domain, zinc finger Zn_Tnp_IS1595 PF12760.2 EIE86053.1 - 0.15 11.8 3.1 0.33 10.7 2.1 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Ima1_N PF09779.4 EIE86053.1 - 0.16 12.4 3.2 0.27 11.7 0.3 2.4 1 1 1 2 2 2 0 Ima1 N-terminal domain DZR PF12773.2 EIE86053.1 - 0.34 10.7 3.3 1 9.2 2.3 1.7 1 1 0 1 1 1 0 Double zinc ribbon Leader_Erm PF08253.6 EIE86054.1 - 0.33 10.4 0.3 0.33 10.4 0.2 2.1 2 0 0 2 2 2 0 Erm Leader peptide HTH_psq PF05225.11 EIE86055.1 - 2.5e-06 26.9 0.0 5.7e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_28 PF13518.1 EIE86055.1 - 1.6e-05 24.7 0.0 3e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.1 EIE86055.1 - 6.9e-05 22.3 0.0 0.00012 21.6 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_1 PF00126.22 EIE86055.1 - 0.0014 18.3 0.0 0.0019 17.9 0.0 1.2 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_7 PF02796.10 EIE86055.1 - 0.0052 16.6 0.1 0.014 15.2 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase DUF2361 PF10153.4 EIE86055.1 - 0.0075 16.4 0.4 0.0093 16.1 0.3 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2361) DUF1804 PF08822.6 EIE86055.1 - 0.0081 15.9 0.1 0.012 15.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1804) Sigma70_r4_2 PF08281.7 EIE86055.1 - 0.0091 15.4 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Sigma-70, region 4 CENP-B_N PF04218.8 EIE86055.1 - 0.01 15.2 0.7 0.022 14.1 0.0 1.9 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain TrmB PF01978.14 EIE86055.1 - 0.018 14.7 0.0 0.041 13.5 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB NUMOD1 PF07453.8 EIE86055.1 - 0.018 14.8 0.0 0.049 13.4 0.0 1.9 1 0 0 1 1 1 0 NUMOD1 domain HTH_38 PF13936.1 EIE86055.1 - 0.024 14.1 0.0 0.06 12.9 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_3 PF01381.17 EIE86055.1 - 0.03 14.1 0.0 0.084 12.7 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix Phage_terminase PF10668.4 EIE86055.1 - 0.88 9.4 5.7 0.8 9.5 0.2 2.5 2 1 0 3 3 3 0 Phage terminase small subunit DDE_3 PF13358.1 EIE86056.1 - 1.8e-30 105.6 0.0 2.9e-30 104.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.14 EIE86056.1 - 0.00077 18.6 0.2 0.0066 15.6 0.2 2.1 1 1 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE86056.1 - 0.02 14.9 0.0 0.042 13.9 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain HTH_29 PF13551.1 EIE86056.1 - 0.061 13.4 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn helix DDE_3 PF13358.1 EIE86057.1 - 8.3e-07 28.8 0.8 1.7e-06 27.8 0.2 1.7 1 1 1 2 2 2 1 DDE superfamily endonuclease HMG_box_2 PF09011.5 EIE86057.1 - 0.12 12.7 0.3 0.17 12.2 0.2 1.1 1 0 0 1 1 1 0 HMG-box domain HMG_box PF00505.14 EIE86057.1 - 0.15 12.3 0.7 0.75 10.1 0.1 1.9 1 1 1 2 2 2 0 HMG (high mobility group) box HTH_Tnp_Tc3_2 PF01498.13 EIE86058.1 - 2.3e-08 33.9 0.6 3.3e-08 33.4 0.4 1.3 1 0 0 1 1 1 1 Transposase SPOR PF05036.8 EIE86058.1 - 0.041 14.0 0.0 0.38 10.9 0.0 1.9 1 1 1 2 2 2 0 Sporulation related domain HTH_29 PF13551.1 EIE86058.1 - 0.055 13.6 0.2 0.066 13.3 0.1 1.1 1 0 0 1 1 1 0 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.13 EIE86059.1 - 1.5e-15 56.9 1.1 7e-15 54.8 0.1 2.3 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.1 EIE86059.1 - 1e-07 31.7 0.0 2e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 EIE86059.1 - 8.5e-07 29.1 0.1 2.7e-06 27.5 0.1 1.9 1 0 0 1 1 1 1 Winged helix-turn helix HTH_7 PF02796.10 EIE86059.1 - 8.8e-07 28.6 1.3 3.4e-05 23.5 0.4 2.7 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_23 PF13384.1 EIE86059.1 - 8.8e-07 28.3 0.1 4.7e-05 22.8 0.0 2.8 3 0 0 3 3 3 1 Homeodomain-like domain HTH_32 PF13565.1 EIE86059.1 - 0.00054 20.7 0.0 0.005 17.5 0.0 2.6 2 1 1 3 3 2 1 Homeodomain-like domain HTH_36 PF13730.1 EIE86059.1 - 0.0006 19.8 1.5 0.0061 16.6 0.4 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_28 PF13518.1 EIE86059.1 - 0.0017 18.3 0.0 0.093 12.7 0.0 3.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_33 PF13592.1 EIE86059.1 - 0.0018 17.7 0.1 0.0054 16.2 0.0 1.9 2 0 0 2 2 2 1 Winged helix-turn helix HTH_Tnp_ISL3 PF13542.1 EIE86059.1 - 0.0027 16.8 0.1 0.098 11.8 0.0 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_38 PF13936.1 EIE86059.1 - 0.0044 16.5 0.0 0.015 14.8 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_11 PF08279.7 EIE86059.1 - 0.0045 16.5 0.3 0.088 12.4 0.1 2.4 2 0 0 2 2 2 1 HTH domain HTH_24 PF13412.1 EIE86059.1 - 0.006 15.9 0.2 0.13 11.7 0.1 2.5 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_3 PF01381.17 EIE86059.1 - 0.015 15.1 0.7 0.1 12.4 0.2 2.1 2 0 0 2 2 2 0 Helix-turn-helix LacI PF00356.16 EIE86059.1 - 0.016 14.8 1.3 2 8.1 0.1 2.5 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family HTH_AsnC-type PF13404.1 EIE86059.1 - 0.02 14.4 0.0 0.043 13.3 0.0 1.5 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_21 PF13276.1 EIE86059.1 - 0.02 14.8 0.0 0.074 13.0 0.0 1.9 2 0 0 2 2 2 0 HTH-like domain Trp_repressor PF01371.14 EIE86059.1 - 0.032 14.1 0.2 0.088 12.7 0.1 1.7 1 0 0 1 1 1 0 Trp repressor protein GerE PF00196.14 EIE86059.1 - 0.033 13.4 1.3 0.059 12.6 0.1 1.9 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family HTH_22 PF13309.1 EIE86059.1 - 0.048 13.4 0.1 0.15 11.8 0.1 1.8 1 0 0 1 1 1 0 HTH domain Sigma54_DBD PF04552.8 EIE86059.1 - 0.079 12.4 1.8 0.28 10.6 0.1 2.4 3 0 0 3 3 2 0 Sigma-54, DNA binding domain GntR PF00392.16 EIE86059.1 - 0.086 12.2 0.1 4.4 6.8 0.0 2.5 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family TrmB PF01978.14 EIE86059.1 - 0.097 12.3 0.6 0.77 9.5 0.2 2.3 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB KorB PF08535.5 EIE86059.1 - 0.1 12.7 0.1 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 KorB domain Acetyltransf_2 PF00797.12 EIE86059.1 - 0.13 11.7 0.9 8.1 5.9 0.0 2.5 2 1 1 3 3 3 0 N-acetyltransferase DDE_3 PF13358.1 EIE86060.1 - 1.3e-12 47.6 0.1 2.4e-12 46.8 0.1 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE86060.1 - 2.8e-10 40.0 1.1 6.9e-10 38.8 0.4 2.0 3 0 0 3 3 3 1 Transposase HTH_Tnp_Tc3_2 PF01498.13 EIE86061.1 - 1.9e-18 66.2 0.6 1.9e-18 66.2 0.4 2.7 3 1 1 4 4 4 1 Transposase DDE_3 PF13358.1 EIE86061.1 - 2.7e-08 33.6 1.3 2e-07 30.8 0.5 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_29 PF13551.1 EIE86061.1 - 1.8e-06 28.0 0.9 6.7e-06 26.2 0.4 2.1 2 1 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.1 EIE86061.1 - 4.2e-05 24.2 4.9 0.0011 19.6 0.2 3.7 3 1 1 4 4 4 1 Homeodomain-like domain HTH_23 PF13384.1 EIE86061.1 - 0.0014 18.1 0.7 0.069 12.8 0.0 3.3 3 0 0 3 3 3 1 Homeodomain-like domain HTH_21 PF13276.1 EIE86061.1 - 0.052 13.5 0.2 1.8 8.6 0.0 3.0 2 1 1 3 3 3 0 HTH-like domain DDE_3 PF13358.1 EIE86062.1 - 1.1e-17 64.1 0.2 2.4e-17 63.0 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE86062.1 - 5.5e-10 39.1 1.1 1.5e-09 37.7 0.8 1.8 1 0 0 1 1 1 1 Transposase FAM70 PF14967.1 EIE86062.1 - 0.045 12.9 0.0 0.068 12.3 0.0 1.2 1 0 0 1 1 1 0 FAM70 protein HTH_Tnp_4 PF13613.1 EIE86062.1 - 0.08 12.4 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease DDE_3 PF13358.1 EIE86063.1 - 8.6e-21 74.2 0.1 1.5e-20 73.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE86063.1 - 1.8e-06 27.9 0.2 1.8e-06 27.9 0.2 1.8 2 0 0 2 2 2 1 Transposase Sigma70_r1_2 PF00140.15 EIE86063.1 - 0.0038 16.8 0.2 0.0083 15.7 0.1 1.6 1 0 0 1 1 1 1 Sigma-70 factor, region 1.2 HTH_Tnp_Tc3_2 PF01498.13 EIE86065.1 - 1.5e-07 31.3 0.4 4.4e-07 29.8 0.1 2.0 2 0 0 2 2 2 1 Transposase Exo_endo_phos_2 PF14529.1 EIE86066.1 - 9.1e-15 54.3 0.0 2.6e-14 52.8 0.0 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EIE86066.1 - 5.3e-06 26.5 0.2 1.4e-05 25.1 0.1 1.7 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF972 PF06156.8 EIE86066.1 - 0.00012 22.4 1.7 0.00021 21.6 1.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF972) TSC22 PF01166.13 EIE86066.1 - 0.00015 21.6 0.6 0.00032 20.5 0.4 1.4 1 0 0 1 1 1 1 TSC-22/dip/bun family DUF904 PF06005.7 EIE86066.1 - 0.038 14.2 2.3 0.082 13.2 1.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DDE_3 PF13358.1 EIE86067.1 - 7.9e-18 64.6 0.1 1.4e-17 63.7 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE86067.1 - 8.9e-06 25.6 0.6 3.2e-05 23.8 0.7 1.7 2 0 0 2 2 2 1 Transposase FAM70 PF14967.1 EIE86068.1 - 0.0024 17.1 0.2 0.0028 16.9 0.1 1.0 1 0 0 1 1 1 1 FAM70 protein DDE_3 PF13358.1 EIE86068.1 - 0.1 12.3 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease DDE_3 PF13358.1 EIE86069.1 - 1.1e-17 64.1 0.0 2.4e-17 63.0 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE86069.1 - 1.5e-09 37.7 0.8 5.6e-09 35.9 0.5 2.0 1 0 0 1 1 1 1 Transposase HTH_Tnp_4 PF13613.1 EIE86069.1 - 0.0008 18.8 0.0 0.0015 18.0 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease HTH_23 PF13384.1 EIE86069.1 - 0.0068 16.0 0.0 0.019 14.5 0.0 1.8 1 1 0 1 1 1 1 Homeodomain-like domain FAM70 PF14967.1 EIE86069.1 - 0.045 12.9 0.0 0.068 12.3 0.0 1.2 1 0 0 1 1 1 0 FAM70 protein TraF_2 PF13729.1 EIE86071.1 - 0.001 17.9 0.6 0.0011 17.8 0.4 1.2 1 0 0 1 1 1 1 F plasmid transfer operon, TraF, protein HTH_Tnp_Tc3_2 PF01498.13 EIE86072.1 - 3.8e-07 30.0 1.4 2.7e-06 27.3 0.2 2.3 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.1 EIE86072.1 - 0.00059 19.3 0.0 0.021 14.4 0.0 2.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.1 EIE86072.1 - 0.0023 17.0 0.5 0.012 14.7 0.1 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_28 PF13518.1 EIE86072.1 - 0.0044 16.9 0.0 0.011 15.6 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain MerR PF00376.18 EIE86072.1 - 0.072 12.6 0.2 0.15 11.6 0.1 1.6 1 0 0 1 1 1 0 MerR family regulatory protein HTH_29 PF13551.1 EIE86072.1 - 0.13 12.4 0.1 0.35 11.0 0.1 1.8 1 1 1 2 2 2 0 Winged helix-turn helix HTH_11 PF08279.7 EIE86072.1 - 0.13 11.8 0.1 0.31 10.7 0.0 1.6 1 0 0 1 1 1 0 HTH domain HTH_36 PF13730.1 EIE86072.1 - 0.55 10.4 0.1 0.55 10.4 0.1 3.1 2 1 0 2 2 2 0 Helix-turn-helix domain Transposase_21 PF02992.9 EIE86073.1 - 0.00048 19.2 0.0 0.00086 18.4 0.0 1.5 1 1 1 2 2 2 1 Transposase family tnp2 DDE_3 PF13358.1 EIE86074.1 - 3.9e-09 36.3 0.1 5.4e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Transposase_21 PF02992.9 EIE86075.1 - 1.2e-05 24.5 0.0 2.2e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 DUF3713 PF12506.3 EIE86075.1 - 0.00013 22.0 0.5 0.00027 20.9 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3713) TGS PF02824.16 EIE86075.1 - 0.028 14.2 0.0 4 7.3 0.0 2.8 2 1 0 2 2 2 0 TGS domain DDE_3 PF13358.1 EIE86076.1 - 4.7e-14 52.3 0.0 7.5e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE86076.1 - 3.4e-10 39.8 0.2 8.3e-10 38.5 0.2 1.7 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.1 EIE86076.1 - 8.2e-06 25.9 0.4 1.5e-05 25.1 0.3 1.4 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EIE86076.1 - 8.9e-05 22.0 0.5 0.00058 19.4 0.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_7 PF02796.10 EIE86076.1 - 0.0016 18.2 0.3 0.062 13.1 0.0 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_28 PF13518.1 EIE86076.1 - 0.0049 16.8 0.5 0.018 15.0 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain rve PF00665.21 EIE86076.1 - 0.0075 16.3 0.0 0.027 14.5 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain SPOR PF05036.8 EIE86076.1 - 0.062 13.4 0.1 0.27 11.4 0.0 1.9 1 1 1 2 2 2 0 Sporulation related domain RTTN_N PF14726.1 EIE86078.1 - 0.057 13.9 0.0 0.15 12.6 0.0 1.7 2 0 0 2 2 2 0 Rotatin, an armadillo repeat protein, centriole functioning HTH_Tnp_Tc3_2 PF01498.13 EIE86079.1 - 1e-05 25.5 1.6 1.5e-05 24.9 0.2 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.1 EIE86082.1 - 2.1e-18 66.4 0.0 2.6e-18 66.1 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE86082.1 - 0.0081 16.2 0.0 0.01 15.9 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain TC1 PF15063.1 EIE86082.1 - 0.087 12.3 0.1 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Thyroid cancer protein 1 HTH_Tnp_Tc3_2 PF01498.13 EIE86084.1 - 8.9e-12 44.9 2.1 1e-11 44.6 0.5 1.8 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 EIE86084.1 - 0.009 16.1 0.9 0.022 14.8 0.1 1.9 2 0 0 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.1 EIE86084.1 - 0.034 13.7 0.1 0.087 12.5 0.1 1.7 1 0 0 1 1 1 0 Homeodomain-like domain DUF1284 PF06935.6 EIE86085.1 - 0.074 13.2 0.0 0.076 13.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1284) DDE_3 PF13358.1 EIE86086.1 - 1.5e-16 60.4 1.0 1.5e-16 60.4 0.2 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease DUF4160 PF13711.1 EIE86086.1 - 0.96 9.3 5.9 7.2 6.5 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4160) DDE_3 PF13358.1 EIE86087.1 - 4.9e-05 23.1 0.0 0.00011 21.9 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE86087.1 - 5.6e-05 23.1 2.1 0.00015 21.7 1.4 1.8 1 1 0 1 1 1 1 Transposase FAM70 PF14967.1 EIE86087.1 - 0.029 13.5 0.0 0.044 12.9 0.0 1.2 1 0 0 1 1 1 0 FAM70 protein DDE_3 PF13358.1 EIE86088.1 - 2.7e-19 69.3 0.1 4.6e-19 68.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE86088.1 - 8.1e-09 35.4 2.8 6.8e-08 32.4 0.9 2.6 3 0 0 3 3 3 1 Transposase HTH_23 PF13384.1 EIE86088.1 - 0.0022 17.5 0.1 0.018 14.7 0.0 2.5 3 0 0 3 3 3 1 Homeodomain-like domain HTH_29 PF13551.1 EIE86088.1 - 0.061 13.4 0.3 0.31 11.1 0.0 2.2 1 1 1 2 2 2 0 Winged helix-turn helix HTH_28 PF13518.1 EIE86088.1 - 0.1 12.6 0.6 1.3 9.0 0.0 2.6 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.13 EIE86089.1 - 4.1e-09 36.3 0.2 1.5e-08 34.5 0.1 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.1 EIE86089.1 - 1.2e-06 28.3 0.0 1.6e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease GHMP_kinases_C PF08544.8 EIE86089.1 - 0.11 12.7 0.0 5.1 7.3 0.0 2.3 2 0 0 2 2 2 0 GHMP kinases C terminal TC1 PF15063.1 EIE86089.1 - 0.11 12.0 0.1 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Thyroid cancer protein 1 DDE_Tnp_IS1595 PF12762.2 EIE86090.1 - 4.1e-18 65.6 0.0 5.5e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 ISXO2-like transposase domain RVT_1 PF00078.22 EIE86091.1 - 6.5e-05 22.3 0.1 0.00013 21.3 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 EIE86091.1 - 0.0018 18.7 0.0 0.0037 17.7 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EIE86091.1 - 0.014 15.1 0.0 0.029 14.2 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease PF09668.5 EIE86091.1 - 0.12 11.9 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease Chromo PF00385.19 EIE86092.1 - 1e-05 25.0 0.7 1e-05 25.0 0.5 2.0 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.21 EIE86093.1 - 1.8e-24 86.1 0.0 5.6e-24 84.5 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE86093.1 - 6.6e-17 61.5 0.0 1.3e-16 60.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE86093.1 - 7.3e-11 41.5 0.6 2.6e-10 39.8 0.4 2.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 EIE86093.1 - 0.00037 19.8 0.1 0.001 18.3 0.1 1.8 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger UBN2_2 PF14227.1 EIE86093.1 - 0.0095 15.4 0.4 0.29 10.7 0.0 2.8 3 0 0 3 3 3 1 gag-polypeptide of LTR copia-type rve_3 PF13683.1 EIE86093.1 - 0.031 13.7 0.0 0.087 12.3 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain UBN2 PF14223.1 EIE86093.1 - 0.07 12.9 0.2 0.26 11.1 0.0 2.0 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type DDE_3 PF13358.1 EIE86094.1 - 1.1e-16 60.9 0.0 2.1e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE86094.1 - 9.9e-08 31.9 0.2 2.2e-07 30.8 0.1 1.6 1 0 0 1 1 1 1 Transposase DDE_Tnp_ISAZ013 PF07592.6 EIE86094.1 - 0.082 11.6 1.0 0.11 11.2 0.0 1.6 2 0 0 2 2 2 0 Rhodopirellula transposase DDE domain Sec23_trunk PF04811.10 EIE86095.1 - 2.8e-47 161.1 0.4 1.8e-32 112.6 0.1 2.2 1 1 1 2 2 2 2 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EIE86095.1 - 2.4e-18 65.4 0.0 6.8e-18 64.0 0.0 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EIE86095.1 - 1.9e-17 63.5 0.0 4.3e-17 62.4 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EIE86095.1 - 5.4e-16 57.8 1.8 1.3e-15 56.6 1.3 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EIE86095.1 - 4.6e-09 35.8 0.0 9.6e-09 34.8 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat ActA PF05058.7 EIE86095.1 - 0.26 9.2 0.3 0.4 8.6 0.2 1.2 1 0 0 1 1 1 0 ActA Protein Urb2 PF10441.4 EIE86096.1 - 6.4e-33 114.2 3.6 6.4e-33 114.2 2.5 3.0 3 0 0 3 3 3 1 Urb2/Npa2 family Telomerase_RBD PF12009.3 EIE86099.1 - 1.1e-10 41.5 7.1 1.6e-10 41.0 4.3 1.7 2 0 0 2 2 2 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.22 EIE86099.1 - 0.00022 20.6 0.2 0.00029 20.2 0.1 1.3 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) D123 PF07065.9 EIE86101.1 - 7.4e-97 324.0 3.5 1.2e-96 323.3 2.5 1.2 1 0 0 1 1 1 1 D123 adh_short_C2 PF13561.1 EIE86101.1 - 2.3e-09 37.3 0.1 5.7e-09 36.1 0.0 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EIE86101.1 - 1e-08 35.3 0.1 1.7e-08 34.5 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase DUF4404 PF14357.1 EIE86101.1 - 0.32 11.4 2.3 1 9.8 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Arrestin_C PF02752.17 EIE86102.1 - 2.3e-08 34.2 0.4 3.3e-08 33.7 0.3 1.3 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EIE86102.1 - 3.6e-08 33.3 1.0 0.00028 20.7 0.0 2.5 2 1 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Pkinase PF00069.20 EIE86103.1 - 1.5e-15 57.0 0.0 2e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE86103.1 - 1.1e-09 37.7 0.0 1.5e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Spt20 PF12090.3 EIE86104.1 - 3.3e-33 114.5 0.1 3.3e-33 114.5 0.0 7.9 2 2 2 5 5 5 1 Spt20 family Ribosomal_L14 PF00238.14 EIE86106.1 - 1.2e-22 79.9 0.1 1.3e-22 79.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Isochorismatase PF00857.15 EIE86107.1 - 2.2e-36 125.4 0.1 3.2e-36 124.8 0.1 1.3 1 1 0 1 1 1 1 Isochorismatase family AAA_25 PF13481.1 EIE86107.1 - 0.05 13.0 0.0 0.1 12.0 0.0 1.4 2 0 0 2 2 2 0 AAA domain ADH_N PF08240.7 EIE86108.1 - 1.5e-20 72.9 2.1 2.3e-20 72.3 1.4 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIE86108.1 - 2.7e-20 72.2 0.0 4.6e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIE86108.1 - 0.00029 21.7 0.0 0.00056 20.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EIE86108.1 - 0.0029 16.7 0.0 0.0053 15.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EIE86108.1 - 0.034 13.6 0.0 0.061 12.8 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ThiF PF00899.16 EIE86108.1 - 0.12 12.1 1.4 0.62 9.8 0.4 2.3 2 0 0 2 2 2 0 ThiF family GCR1_C PF12550.3 EIE86111.1 - 6.3e-24 83.6 4.8 1.9e-23 82.1 3.3 1.9 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes ADH_N PF08240.7 EIE86112.1 - 1.5e-20 72.9 2.1 2.3e-20 72.3 1.4 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIE86112.1 - 2.7e-20 72.2 0.0 4.6e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIE86112.1 - 0.00029 21.7 0.0 0.00056 20.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EIE86112.1 - 0.0029 16.7 0.0 0.0053 15.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EIE86112.1 - 0.034 13.6 0.0 0.061 12.8 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ThiF PF00899.16 EIE86112.1 - 0.12 12.1 1.4 0.62 9.8 0.4 2.3 2 0 0 2 2 2 0 ThiF family ATG16 PF08614.6 EIE86113.1 - 0.014 15.1 17.2 0.028 14.2 11.9 1.7 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF948 PF06103.6 EIE86113.1 - 0.022 14.6 0.9 0.047 13.5 0.5 1.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) YPEB PF14620.1 EIE86113.1 - 0.025 13.6 8.9 0.036 13.0 6.2 1.2 1 0 0 1 1 1 0 YpeB sporulation Reo_sigmaC PF04582.7 EIE86113.1 - 0.052 12.7 2.0 0.07 12.3 1.4 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein PAZ_siRNAbind PF12212.3 EIE86113.1 - 0.054 13.1 2.6 0.22 11.1 1.8 2.1 1 0 0 1 1 1 0 Piwi/Argonaute/Zwille siRNA-binding domain COG2 PF06148.6 EIE86113.1 - 0.1 12.4 6.5 0.24 11.2 4.5 1.7 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF489 PF04356.7 EIE86113.1 - 0.18 11.4 2.6 0.22 11.0 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF489) Snapin_Pallidin PF14712.1 EIE86113.1 - 0.35 11.1 7.3 0.29 11.4 3.4 2.2 1 1 1 2 2 2 0 Snapin/Pallidin DUF4140 PF13600.1 EIE86113.1 - 0.42 11.0 9.7 1.4 9.3 0.6 2.8 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) DUF445 PF04286.7 EIE86113.1 - 0.6 9.5 10.9 0.7 9.3 7.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) NPV_P10 PF05531.7 EIE86113.1 - 0.68 10.2 7.7 14 5.9 5.2 2.9 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein 3-dmu-9_3-mt PF06983.8 EIE86113.1 - 1.1 9.6 3.9 2.1 8.7 0.1 2.8 2 1 1 3 3 3 0 3-demethylubiquinone-9 3-methyltransferase DegQ PF08181.6 EIE86113.1 - 2.5 7.8 12.2 0.066 12.9 2.1 2.7 2 0 0 2 2 2 0 DegQ (SacQ) family DUF607 PF04678.8 EIE86113.1 - 2.8 7.8 5.7 6.9 6.5 4.0 1.8 1 1 0 1 1 1 0 Protein of unknown function, DUF607 bZIP_1 PF00170.16 EIE86113.1 - 3 7.8 11.9 2.3 8.2 1.7 2.8 2 1 0 2 2 2 0 bZIP transcription factor DivIC PF04977.10 EIE86113.1 - 3.1 7.3 13.0 3.4 7.2 0.7 3.0 1 1 1 2 2 2 0 Septum formation initiator Cob_adeno_trans PF01923.13 EIE86113.1 - 6.8 6.4 7.2 18 5.0 3.0 2.7 1 1 2 3 3 3 0 Cobalamin adenosyltransferase DUF1664 PF07889.7 EIE86113.1 - 7.5 6.3 11.0 5.9 6.7 0.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Cyclin_N PF00134.18 EIE86114.1 - 1.2e-18 66.9 2.0 2.9e-16 59.2 0.4 2.3 1 1 1 2 2 2 2 Cyclin, N-terminal domain TFIIB PF00382.14 EIE86114.1 - 8.4e-07 28.7 0.1 0.00098 18.8 0.0 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat Cyclin_C PF02984.14 EIE86114.1 - 0.00039 20.3 9.8 0.0032 17.3 6.8 2.3 1 1 0 1 1 1 1 Cyclin, C-terminal domain 2Fe-2S_thioredx PF01257.14 EIE86114.1 - 0.055 13.0 0.2 0.092 12.3 0.1 1.3 1 0 0 1 1 1 0 Thioredoxin-like [2Fe-2S] ferredoxin DUF4231 PF14015.1 EIE86115.1 - 0.016 15.1 1.3 0.026 14.5 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) DUF3093 PF11292.3 EIE86115.1 - 0.034 13.9 2.2 0.061 13.1 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3093) ABC2_membrane_2 PF12679.2 EIE86115.1 - 0.043 12.6 0.3 0.05 12.4 0.2 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Gam PF06064.6 EIE86115.1 - 0.06 13.4 0.0 0.093 12.8 0.0 1.3 1 0 0 1 1 1 0 Host-nuclease inhibitor protein Gam DUF4191 PF13829.1 EIE86115.1 - 0.13 11.3 0.5 0.17 10.9 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) DUF4131 PF13567.1 EIE86115.1 - 4.9 6.5 6.2 8.1 5.8 4.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) DUF3336 PF11815.3 EIE86116.1 - 3e-23 81.9 0.0 2.4e-22 79.0 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EIE86116.1 - 9.3e-15 55.0 0.0 2.1e-14 53.9 0.0 1.5 2 0 0 2 2 2 1 Patatin-like phospholipase Pkinase PF00069.20 EIE86117.1 - 3e-57 193.7 0.0 5.6e-57 192.8 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE86117.1 - 1.1e-28 100.0 0.0 1.5e-28 99.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EIE86117.1 - 0.0061 15.6 0.2 0.023 13.7 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIE86117.1 - 0.01 15.5 0.1 0.027 14.1 0.1 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family zf-H2C2_2 PF13465.1 EIE86118.1 - 2.1e-09 37.1 13.4 0.00015 21.9 0.4 3.4 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 EIE86118.1 - 1.9e-06 27.8 10.8 0.015 15.5 3.1 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIE86118.1 - 2.8e-05 24.1 10.3 0.031 14.5 3.0 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 EIE86118.1 - 0.043 14.0 6.6 0.044 14.0 1.8 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EIE86118.1 - 0.093 12.9 5.7 0.13 12.4 2.6 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 EIE86118.1 - 0.17 11.6 8.0 2.6 7.8 2.1 2.4 2 0 0 2 2 2 0 BED zinc finger zf-C2H2_6 PF13912.1 EIE86118.1 - 1.4 8.9 5.6 9.1 6.3 1.7 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger Acyltransferase PF01553.16 EIE86119.1 - 9.2e-23 80.1 0.0 1.2e-22 79.7 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase US2 PF02476.10 EIE86119.1 - 0.1 13.0 0.0 0.2 12.1 0.0 1.4 1 0 0 1 1 1 0 US2 family Cyclin PF08613.6 EIE86120.1 - 6.8e-16 59.0 0.1 1.7e-15 57.6 0.0 1.8 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 EIE86120.1 - 7.2e-07 28.8 0.1 7.2e-07 28.8 0.1 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Aldedh PF00171.17 EIE86121.1 - 9e-72 241.8 0.0 1.9e-71 240.7 0.0 1.5 1 1 0 1 1 1 1 Aldehyde dehydrogenase family Anp1 PF03452.9 EIE86122.1 - 6.2e-76 255.1 0.0 8e-76 254.7 0.0 1.1 1 0 0 1 1 1 1 Anp1 OHA PF14418.1 EIE86122.1 - 0.041 13.3 0.1 1.5 8.4 0.0 2.4 2 0 0 2 2 2 0 OST-HTH Associated domain PTPA PF03095.10 EIE86123.1 - 9.9e-108 359.8 0.4 1.2e-107 359.6 0.3 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Ribosomal_S9 PF00380.14 EIE86124.1 - 2.8e-40 137.3 0.2 4.1e-40 136.7 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Pkinase PF00069.20 EIE86125.1 - 7.2e-52 176.0 0.0 8.9e-52 175.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE86125.1 - 3.2e-22 78.8 0.1 3.9e-22 78.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE86125.1 - 1.5e-05 24.1 0.1 0.00013 21.0 0.0 1.9 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 EIE86125.1 - 0.0081 15.9 0.1 0.024 14.3 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family FUSC_2 PF13515.1 EIE86126.1 - 1.2e-15 57.5 19.5 2.3e-15 56.6 13.5 1.5 1 0 0 1 1 1 1 Fusaric acid resistance protein-like DUF2421 PF10334.4 EIE86126.1 - 4.8e-15 55.8 0.0 7.9e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2421) ALMT PF11744.3 EIE86126.1 - 4.1e-09 35.5 0.5 5.2e-09 35.2 0.3 1.1 1 0 0 1 1 1 1 Aluminium activated malate transporter FUSC PF04632.7 EIE86126.1 - 0.0001 20.9 14.3 0.00016 20.2 9.9 1.3 1 0 0 1 1 1 1 Fusaric acid resistance protein family DUF2422 PF10337.4 EIE86127.1 - 1.7e-05 23.8 2.3 2.2e-05 23.4 1.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2422) O-antigen_lig PF13425.1 EIE86127.1 - 0.021 14.8 0.2 0.025 14.5 0.2 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Intg_mem_TP0381 PF09529.5 EIE86127.1 - 0.065 12.4 0.7 0.079 12.1 0.5 1.1 1 0 0 1 1 1 0 Integral membrane protein (intg_mem_TP0381) DUF3353 PF11833.3 EIE86127.1 - 0.069 12.6 0.6 0.081 12.3 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3353) 7TM_transglut PF14402.1 EIE86127.1 - 0.083 11.8 0.3 0.089 11.7 0.2 1.1 1 0 0 1 1 1 0 7 transmembrane helices usually fused to an inactive transglutaminase Mito_carr PF00153.22 EIE86128.1 - 6.4e-79 259.7 1.2 3.4e-26 90.7 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein PTR2 PF00854.16 EIE86129.1 - 1.2e-53 182.2 13.7 1.2e-53 182.2 9.5 1.5 2 0 0 2 2 2 1 POT family MFS_1 PF07690.11 EIE86129.1 - 0.00018 20.3 26.2 0.00018 20.3 18.1 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Orbi_NS3 PF01616.11 EIE86129.1 - 0.055 12.4 0.0 0.11 11.4 0.0 1.6 1 0 0 1 1 1 0 Orbivirus NS3 DUF1772 PF08592.6 EIE86129.1 - 6.2 6.5 12.5 3.2 7.5 1.5 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF1772) RNA_capsid PF03035.9 EIE86132.1 - 0.2 11.3 1.9 0.24 11.1 1.3 1.1 1 0 0 1 1 1 0 Calicivirus putative RNA polymerase/capsid protein AMP-binding PF00501.23 EIE86133.1 - 1.1e-92 310.6 0.0 1.4e-92 310.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EIE86133.1 - 9.7e-11 42.4 0.1 9.7e-11 42.4 0.1 2.4 4 0 0 4 4 4 1 AMP-binding enzyme C-terminal domain DUF2422 PF10337.4 EIE86134.1 - 1.7e-05 23.8 2.3 2.2e-05 23.4 1.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2422) O-antigen_lig PF13425.1 EIE86134.1 - 0.021 14.8 0.2 0.025 14.5 0.2 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Intg_mem_TP0381 PF09529.5 EIE86134.1 - 0.065 12.4 0.7 0.079 12.1 0.5 1.1 1 0 0 1 1 1 0 Integral membrane protein (intg_mem_TP0381) DUF3353 PF11833.3 EIE86134.1 - 0.069 12.6 0.6 0.081 12.3 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3353) 7TM_transglut PF14402.1 EIE86134.1 - 0.083 11.8 0.3 0.089 11.7 0.2 1.1 1 0 0 1 1 1 0 7 transmembrane helices usually fused to an inactive transglutaminase FUSC_2 PF13515.1 EIE86135.1 - 1.2e-15 57.5 19.5 2.3e-15 56.6 13.5 1.5 1 0 0 1 1 1 1 Fusaric acid resistance protein-like DUF2421 PF10334.4 EIE86135.1 - 2.8e-15 56.5 0.1 5.2e-15 55.6 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2421) ALMT PF11744.3 EIE86135.1 - 3.9e-09 35.6 0.6 4.7e-09 35.3 0.4 1.1 1 0 0 1 1 1 1 Aluminium activated malate transporter FUSC PF04632.7 EIE86135.1 - 5.6e-05 21.7 13.5 9.4e-05 21.0 9.4 1.3 1 0 0 1 1 1 1 Fusaric acid resistance protein family Arf PF00025.16 EIE86136.1 - 4.1e-07 29.4 0.0 4.5e-07 29.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EIE86136.1 - 0.04 13.3 0.0 0.044 13.2 0.0 1.0 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain HSP70 PF00012.15 EIE86137.1 - 8.1e-07 27.3 0.0 0.0004 18.4 0.0 2.3 2 0 0 2 2 2 2 Hsp70 protein CBS PF00571.23 EIE86138.1 - 2.1e-37 126.6 7.3 8.5e-09 35.0 0.0 4.5 4 1 0 4 4 4 4 CBS domain DEAD_assoc PF08494.6 EIE86138.1 - 0.036 13.8 1.1 4 7.1 0.0 2.3 2 0 0 2 2 2 0 DEAD/H associated TFIIF_alpha PF05793.7 EIE86140.1 - 1.4e-25 89.6 64.0 1.6e-22 79.5 41.5 3.7 2 1 0 2 2 2 2 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) AAA_11 PF13086.1 EIE86141.1 - 5.8e-63 212.6 0.5 5.8e-63 212.6 0.3 2.0 2 1 0 2 2 2 1 AAA domain AAA_12 PF13087.1 EIE86141.1 - 7.8e-57 191.8 0.0 2.7e-56 190.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain SEN1_N PF12726.2 EIE86141.1 - 1.1e-36 126.2 9.6 1.9e-36 125.4 6.7 1.4 1 0 0 1 1 1 1 SEN1 N terminal AAA_19 PF13245.1 EIE86141.1 - 7.5e-15 54.4 0.1 2.4e-14 52.8 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EIE86141.1 - 1.7e-11 44.1 0.2 3.5e-08 33.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain UvrD-helicase PF00580.16 EIE86141.1 - 2e-08 33.9 2.9 3.1e-06 26.7 0.0 3.2 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain DEAD PF00270.24 EIE86141.1 - 1.6e-05 24.4 0.2 0.00012 21.5 0.0 2.4 1 1 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 EIE86141.1 - 6.3e-05 22.8 0.1 0.00048 20.0 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.9 EIE86141.1 - 0.0041 16.7 0.1 0.05 13.2 0.0 2.7 2 0 0 2 2 2 1 Helicase AAA_25 PF13481.1 EIE86141.1 - 0.019 14.3 0.0 0.044 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EIE86141.1 - 0.025 14.7 0.1 0.14 12.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 EIE86141.1 - 0.067 13.3 0.1 0.6 10.3 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Cyanate_lyase PF02560.9 EIE86141.1 - 0.092 12.2 0.0 0.25 10.8 0.0 1.7 1 0 0 1 1 1 0 Cyanate lyase C-terminal domain AAA_16 PF13191.1 EIE86141.1 - 0.1 12.6 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.13 EIE86141.1 - 0.1 12.0 0.7 0.35 10.2 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF3546 PF12066.3 EIE86142.1 - 2.9e-20 72.3 11.3 1e-19 70.5 7.8 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3546) ARS2 PF04959.8 EIE86142.1 - 1.6e-18 67.6 1.1 1.6e-18 67.6 0.8 2.2 2 0 0 2 2 2 1 Arsenite-resistance protein 2 DUF4187 PF13821.1 EIE86142.1 - 5e-12 45.2 8.2 5e-12 45.2 5.7 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4187) zf-C2H2 PF00096.21 EIE86142.1 - 0.09 13.1 0.3 0.09 13.1 0.2 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIE86142.1 - 0.13 12.7 0.1 0.13 12.7 0.1 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger Kinesin PF00225.18 EIE86143.1 - 1.5e-90 303.2 0.0 1.5e-90 303.2 0.0 2.1 2 1 0 2 2 2 1 Kinesin motor domain Fib_alpha PF08702.5 EIE86143.1 - 3.1 7.9 22.0 16 5.6 11.3 2.9 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Atg14 PF10186.4 EIE86143.1 - 6.2 5.6 22.3 11 4.7 0.2 2.3 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Pkinase PF00069.20 EIE86144.1 - 1.8e-48 164.9 0.3 6.3e-31 107.4 0.1 2.5 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIE86144.1 - 9.9e-28 96.9 0.0 2.9e-15 56.0 0.0 3.2 3 1 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 EIE86144.1 - 0.0012 17.8 0.0 0.011 14.7 0.0 2.4 3 0 0 3 3 3 1 Kinase-like DUF2682 PF10909.3 EIE86144.1 - 0.12 12.6 2.0 0.21 11.8 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2682) SH3_9 PF14604.1 EIE86145.1 - 5.3e-09 35.5 0.0 9.5e-09 34.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EIE86145.1 - 4.5e-07 29.1 0.5 7.6e-07 28.4 0.0 1.7 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 EIE86145.1 - 0.00017 21.0 0.0 0.0003 20.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Amnionless PF14828.1 EIE86145.1 - 0.0029 16.1 0.0 0.0044 15.5 0.0 1.3 1 0 0 1 1 1 1 Amnionless Podoplanin PF05808.6 EIE86145.1 - 0.017 14.6 1.2 0.08 12.4 0.1 2.1 2 0 0 2 2 2 0 Podoplanin DUF2668 PF10873.3 EIE86145.1 - 0.086 12.9 2.1 0.076 13.1 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2668) Ribonuc_L-PSP PF01042.16 EIE86146.1 - 3.7e-20 71.8 0.0 4.2e-20 71.6 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Leader_Erm PF08253.6 EIE86147.1 - 0.33 10.4 0.3 0.33 10.4 0.2 1.9 2 0 0 2 2 2 0 Erm Leader peptide rve PF00665.21 EIE86149.1 - 2.9e-20 72.5 0.0 8.5e-20 71.0 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE86149.1 - 4.4e-11 42.5 0.3 9.1e-11 41.5 0.2 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE86149.1 - 2.1e-10 40.0 0.4 5.6e-10 38.7 0.3 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.12 EIE86149.1 - 9.3e-05 22.4 0.9 0.00037 20.5 0.1 2.4 2 0 0 2 2 2 1 Retrotransposon gag protein DDE_3 PF13358.1 EIE86151.1 - 5.2e-10 39.2 0.2 2.9e-06 27.0 0.4 2.3 1 1 1 2 2 2 2 DDE superfamily endonuclease NUDIX_4 PF14815.1 EIE86151.1 - 0.016 14.6 0.2 0.021 14.2 0.1 1.2 1 0 0 1 1 1 0 NUDIX domain S10_plectin PF03501.10 EIE86151.1 - 0.055 13.3 0.0 0.088 12.6 0.0 1.4 1 0 0 1 1 1 0 Plectin/S10 domain TrmB PF01978.14 EIE86151.1 - 0.16 11.6 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Retrotrans_gag PF03732.12 EIE86152.1 - 2.4e-05 24.3 0.0 5.2e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein rve PF00665.21 EIE86153.1 - 1.1e-18 67.4 0.0 2.5e-18 66.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE86153.1 - 2.1e-16 59.9 0.4 4.8e-16 58.7 0.1 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE86153.1 - 1.7e-13 50.0 1.8 4.4e-13 48.6 1.3 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Myb_DNA-bind_4 PF13837.1 EIE86154.1 - 0.0001 22.3 0.8 0.00012 22.0 0.6 1.1 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 EIE86154.1 - 0.00096 18.9 2.0 0.0016 18.2 1.4 1.5 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.2 EIE86154.1 - 0.0029 18.1 0.2 0.0034 17.9 0.1 1.1 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DDE_3 PF13358.1 EIE86155.1 - 2.5e-20 72.7 0.1 4.7e-20 71.8 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE86155.1 - 6.9e-19 67.6 3.3 7.2e-19 67.6 0.6 2.3 3 0 0 3 3 3 1 Transposase HTH_29 PF13551.1 EIE86155.1 - 1.9e-08 34.3 0.5 7.5e-08 32.5 0.4 1.9 2 0 0 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.1 EIE86155.1 - 3.5e-05 23.3 0.4 0.001 18.6 0.0 3.0 3 0 0 3 3 3 1 Homeodomain-like domain HTH_32 PF13565.1 EIE86155.1 - 0.00052 20.7 5.4 0.0011 19.7 0.2 3.8 4 1 1 5 5 4 1 Homeodomain-like domain Ku_PK_bind PF08785.6 EIE86155.1 - 0.0042 16.9 0.1 0.018 14.9 0.0 2.0 2 0 0 2 2 2 1 Ku C terminal domain like HTH_17 PF12728.2 EIE86155.1 - 0.0053 16.9 0.7 0.077 13.2 0.0 3.0 3 0 0 3 3 3 1 Helix-turn-helix domain rve PF00665.21 EIE86155.1 - 0.0059 16.7 0.0 0.025 14.7 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain HTH_28 PF13518.1 EIE86155.1 - 0.012 15.5 0.0 0.046 13.7 0.0 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_40 PF14493.1 EIE86155.1 - 0.016 15.4 0.4 0.31 11.2 0.0 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain Trp_repressor PF01371.14 EIE86155.1 - 0.02 14.7 0.0 0.16 11.9 0.0 2.2 2 0 0 2 2 2 0 Trp repressor protein HTH_21 PF13276.1 EIE86155.1 - 0.03 14.3 0.1 0.23 11.4 0.0 2.5 2 0 0 2 2 2 0 HTH-like domain HTH_7 PF02796.10 EIE86155.1 - 0.075 12.9 0.7 0.35 10.7 0.1 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_IclR PF09339.5 EIE86155.1 - 0.13 11.9 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 IclR helix-turn-helix domain Plant_tran PF04827.9 EIE86156.1 - 2.7e-103 343.7 0.0 4.3e-103 343.0 0.0 1.3 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_4 PF13359.1 EIE86156.1 - 2e-16 60.0 0.0 2.8e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease BRX PF08381.6 EIE86157.1 - 0.065 12.3 0.5 0.14 11.2 0.3 1.5 1 0 0 1 1 1 0 Transcription factor regulating root and shoot growth via Pin3 DDE_3 PF13358.1 EIE86158.1 - 1.1e-15 57.7 0.2 1.3e-15 57.4 0.2 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE86158.1 - 0.056 13.5 0.0 0.065 13.3 0.0 1.2 1 0 0 1 1 1 0 Integrase core domain rve PF00665.21 EIE86162.1 - 5.5e-24 84.5 0.0 2.2e-23 82.6 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 EIE86162.1 - 1.1e-13 51.1 0.1 3.5e-13 49.3 0.0 1.9 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE86162.1 - 1.1e-08 34.5 0.9 1.2e-07 31.2 0.1 2.9 3 0 0 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.12 EIE86162.1 - 2.3e-06 27.5 0.2 2.3e-06 27.5 0.1 3.0 2 0 0 2 2 2 1 Retrotransposon gag protein rve_3 PF13683.1 EIE86162.1 - 0.0057 16.1 0.0 0.025 14.1 0.0 2.2 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.12 EIE86163.1 - 2.9e-08 33.6 0.1 5.4e-08 32.7 0.1 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein DDE_3 PF13358.1 EIE86165.1 - 3.1e-08 33.4 0.0 4.5e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease PapC_C PF13953.1 EIE86166.1 - 0.09 12.4 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 PapC C-terminal domain Pyr_redox_2 PF07992.9 EIE86167.1 - 5.9e-06 26.2 0.0 6.4e-06 26.1 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.11 EIE86168.1 - 1.2e-55 188.6 29.9 2.3e-51 174.6 16.7 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIE86168.1 - 7.8e-11 41.2 8.1 7.8e-11 41.2 5.6 3.0 2 1 0 2 2 2 1 Sugar (and other) transporter Polysacc_synt_3 PF13440.1 EIE86168.1 - 5.7e-06 25.9 8.4 5.7e-06 25.9 5.8 2.9 2 1 1 3 3 3 1 Polysaccharide biosynthesis protein MFS_3 PF05977.8 EIE86168.1 - 0.00036 18.8 2.7 0.00036 18.8 1.9 2.3 2 0 0 2 2 2 2 Transmembrane secretion effector Co_AT_N PF12557.3 EIE86168.1 - 0.026 14.4 1.9 0.046 13.6 1.3 1.4 1 0 0 1 1 1 0 Cob(I)alamin adenosyltransferase N terminal UPF0227 PF05728.7 EIE86168.1 - 0.24 11.1 0.7 16 5.1 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) Glyco_hydro_16 PF00722.16 EIE86169.1 - 9.6e-29 99.9 0.3 1.2e-28 99.6 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Band_7 PF01145.20 EIE86170.1 - 1.9e-24 86.5 3.7 2.4e-24 86.2 2.2 1.4 1 1 0 1 1 1 1 SPFH domain / Band 7 family DUF2884 PF11101.3 EIE86170.1 - 0.018 14.4 0.9 0.028 13.7 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2884) DUF3811 PF11656.3 EIE86170.1 - 0.3 11.1 2.9 0.49 10.4 1.4 1.7 1 1 0 1 1 1 0 YjbD family (DUF3811) PIG-X PF08320.7 EIE86171.1 - 9.1e-28 96.9 1.2 5.6e-27 94.3 0.9 1.8 1 1 0 1 1 1 1 PIG-X / PBN1 VHS PF00790.14 EIE86172.1 - 3.6e-38 130.3 1.1 2.4e-36 124.4 0.0 2.5 2 0 0 2 2 2 1 VHS domain FYVE PF01363.16 EIE86172.1 - 2.3e-18 65.8 7.3 5.3e-18 64.6 5.1 1.6 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.15 EIE86172.1 - 0.00017 20.9 5.7 0.047 13.2 3.0 2.7 2 0 0 2 2 2 2 Ubiquitin interaction motif FYVE_2 PF02318.11 EIE86172.1 - 0.00021 21.1 3.8 0.00052 19.8 2.6 1.6 1 0 0 1 1 1 1 FYVE-type zinc finger Hrs_helical PF12210.3 EIE86172.1 - 0.0005 20.2 0.5 0.0005 20.2 0.3 2.1 3 0 0 3 3 3 1 Hepatocyte growth factor-regulated tyrosine kinase substrate GAT PF03127.9 EIE86172.1 - 0.0019 18.1 0.6 0.0019 18.1 0.4 3.0 2 1 1 3 3 3 1 GAT domain IBR PF01485.16 EIE86172.1 - 0.0039 17.0 1.9 0.0095 15.7 1.3 1.6 1 0 0 1 1 1 1 IBR domain HypA PF01155.14 EIE86172.1 - 0.027 14.1 0.1 0.07 12.8 0.0 1.8 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-DHHC PF01529.15 EIE86172.1 - 0.55 9.6 9.2 1.5 8.1 2.1 2.7 2 0 0 2 2 2 0 DHHC palmitoyltransferase Ribonuc_L-PSP PF01042.16 EIE86173.1 - 5.4e-18 64.8 0.0 6.6e-18 64.6 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP RHSP PF07999.6 EIE86173.1 - 0.055 12.0 0.0 0.06 11.9 0.0 1.0 1 0 0 1 1 1 0 Retrotransposon hot spot protein Exo_endo_phos_2 PF14529.1 EIE86174.1 - 3.2e-06 26.7 0.1 5.9e-06 25.8 0.1 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EIE86174.1 - 0.00083 19.3 0.1 0.0017 18.3 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Osmo_CC PF08946.5 EIE86174.1 - 2.8 8.0 6.0 3 7.9 0.5 2.7 2 0 0 2 2 2 0 Osmosensory transporter coiled coil BBP1_C PF15272.1 EIE86176.1 - 0.046 13.2 0.2 0.048 13.2 0.1 1.1 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal EF-hand_6 PF13405.1 EIE86177.1 - 0.038 13.8 0.0 0.087 12.7 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain DUF3595 PF12166.3 EIE86177.1 - 0.049 12.4 0.2 0.054 12.3 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3595) EF-hand_1 PF00036.27 EIE86177.1 - 0.065 12.5 0.0 0.2 11.0 0.0 1.8 2 0 0 2 2 2 0 EF hand DDE_3 PF13358.1 EIE86178.1 - 3.3e-14 52.8 0.0 1.2e-13 51.0 0.0 1.8 1 1 0 1 1 1 1 DDE superfamily endonuclease Septin PF00735.13 EIE86179.1 - 1.2e-103 346.0 1.0 2.8e-103 344.7 0.7 1.6 1 1 0 1 1 1 1 Septin Pyridox_oxase_2 PF12766.2 EIE86179.1 - 1.7e-14 53.9 0.1 5.8e-14 52.2 0.0 2.0 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF258 PF03193.11 EIE86179.1 - 3.1e-06 26.4 0.1 9.1e-06 24.9 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EIE86179.1 - 7.4e-06 25.8 0.0 4.3e-05 23.4 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase Pyridox_oxidase PF01243.15 EIE86179.1 - 5.7e-05 23.0 0.0 0.00013 21.8 0.0 1.6 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase AAA_22 PF13401.1 EIE86179.1 - 9.4e-05 22.5 0.4 0.0019 18.3 0.0 2.8 2 1 0 2 2 2 1 AAA domain PduV-EutP PF10662.4 EIE86179.1 - 0.00021 20.7 0.2 0.00076 18.9 0.0 2.0 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 EIE86179.1 - 0.00064 20.2 0.2 0.0033 17.9 0.0 2.5 2 1 0 2 2 2 1 Miro-like protein Pox_A32 PF04665.7 EIE86179.1 - 0.0038 16.5 1.1 0.0062 15.8 0.2 1.7 2 0 0 2 2 2 1 Poxvirus A32 protein FtsK_SpoIIIE PF01580.13 EIE86179.1 - 0.0074 15.7 0.1 0.021 14.2 0.1 1.7 1 0 0 1 1 1 1 FtsK/SpoIIIE family GTP_EFTU PF00009.22 EIE86179.1 - 0.0075 15.7 2.4 0.9 8.9 0.2 3.8 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain KAP_NTPase PF07693.9 EIE86179.1 - 0.01 14.8 1.1 0.075 12.0 0.7 2.0 1 1 0 1 1 1 1 KAP family P-loop domain RNA_helicase PF00910.17 EIE86179.1 - 0.026 14.7 0.0 0.15 12.2 0.0 2.3 2 0 0 2 2 2 0 RNA helicase ABC_tran PF00005.22 EIE86179.1 - 0.044 14.0 0.3 0.52 10.6 0.0 2.5 2 1 0 2 2 2 0 ABC transporter AAA_33 PF13671.1 EIE86179.1 - 0.094 12.5 1.3 0.32 10.8 0.0 2.6 4 0 0 4 4 4 0 AAA domain Dynamin_N PF00350.18 EIE86179.1 - 0.14 11.9 2.0 6.3 6.5 0.0 3.2 3 0 0 3 3 3 0 Dynamin family Cep57_CLD_2 PF14197.1 EIE86179.1 - 0.2 11.6 6.8 0.51 10.3 4.7 1.6 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 MCRS_N PF13325.1 EIE86179.1 - 0.34 10.3 8.8 0.71 9.3 6.1 1.5 1 0 0 1 1 1 0 N-terminal region of micro-spherule protein V_ATPase_I PF01496.14 EIE86179.1 - 3 5.5 7.6 4.1 5.1 5.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Polysacc_deac_1 PF01522.16 EIE86180.1 - 1e-22 80.0 0.0 1.6e-22 79.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 EIE86180.1 - 6.5e-05 21.9 0.0 9.1e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 Hamartin PF04388.7 EIE86180.1 - 0.073 11.7 2.4 0.11 11.2 1.7 1.2 1 0 0 1 1 1 0 Hamartin protein EF-hand_6 PF13405.1 EIE86182.1 - 0.038 13.8 0.0 0.087 12.7 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain DUF3595 PF12166.3 EIE86182.1 - 0.049 12.4 0.2 0.054 12.3 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3595) EF-hand_1 PF00036.27 EIE86182.1 - 0.065 12.5 0.0 0.2 11.0 0.0 1.8 2 0 0 2 2 2 0 EF hand zf-CCHC PF00098.18 EIE86183.1 - 7.2e-08 31.9 10.4 7.6e-05 22.4 0.5 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 EIE86183.1 - 0.00043 19.8 4.3 0.1 12.3 0.5 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.1 EIE86183.1 - 0.02 14.3 6.4 0.55 9.7 2.1 2.3 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC_6 PF15288.1 EIE86183.1 - 0.034 13.8 12.5 0.06 13.0 0.6 2.8 2 1 1 3 3 3 0 Zinc knuckle Lar_restr_allev PF14354.1 EIE86183.1 - 0.33 11.2 4.1 0.7 10.2 2.9 1.6 1 0 0 1 1 1 0 Restriction alleviation protein Lar DnaJ_CXXCXGXG PF00684.14 EIE86183.1 - 0.66 10.0 5.5 3.9 7.5 3.8 2.1 1 1 0 1 1 1 0 DnaJ central domain zf-CCHC_3 PF13917.1 EIE86183.1 - 2.4 7.9 7.6 2.8 7.7 0.5 2.3 1 1 1 2 2 2 0 Zinc knuckle Cyclin PF08613.6 EIE86184.1 - 1.5e-18 67.6 0.1 1.9e-18 67.2 0.1 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EIE86184.1 - 6.7e-06 25.6 0.1 9.6e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain RNB PF00773.14 EIE86185.1 - 2.5e-51 174.9 0.8 3.1e-51 174.6 0.0 1.5 2 0 0 2 2 2 1 RNB domain OB_RNB PF08206.6 EIE86185.1 - 0.14 11.7 0.0 0.36 10.3 0.0 1.8 1 0 0 1 1 1 0 Ribonuclease B OB domain ArfGap PF01412.13 EIE86186.1 - 5.5e-39 132.5 0.0 6e-39 132.4 0.0 1.0 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Paired_CXXCH_1 PF09699.5 EIE86186.1 - 0.064 12.7 0.5 0.2 11.1 0.0 2.0 2 0 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) WD40 PF00400.27 EIE86190.1 - 9.6e-08 31.6 0.0 5.7e-05 22.8 0.0 2.6 3 0 0 3 3 3 2 WD domain, G-beta repeat PFO_beta_C PF12367.3 EIE86191.1 - 0.12 12.3 1.7 0.15 12.0 0.8 1.5 1 1 0 1 1 1 0 Pyruvate ferredoxin oxidoreductase beta subunit C terminal Ribonuc_L-PSP PF01042.16 EIE86192.1 - 5.6e-19 68.0 0.0 6.8e-19 67.8 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP RHSP PF07999.6 EIE86192.1 - 0.098 11.2 0.0 0.1 11.1 0.0 1.0 1 0 0 1 1 1 0 Retrotransposon hot spot protein p450 PF00067.17 EIE86193.1 - 7.5e-55 186.2 0.0 1.2e-38 132.7 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 SWIRM PF04433.12 EIE86194.1 - 1.8e-33 114.4 0.0 5.3e-33 112.9 0.0 1.9 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 EIE86194.1 - 7e-11 42.0 0.0 1.7e-10 40.7 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EIE86194.1 - 2.6e-07 30.6 0.1 7.6e-07 29.1 0.1 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.12 EIE86194.1 - 3.2e-06 26.5 5.9 6.6e-06 25.5 4.1 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type Zn_ribbon_2 PF12674.2 EIE86194.1 - 0.0049 17.1 2.6 0.021 15.1 1.8 2.1 1 0 0 1 1 1 1 Putative zinc ribbon domain Chordopox_RPO7 PF05864.7 EIE86194.1 - 0.047 13.7 0.9 0.12 12.4 0.6 1.6 1 0 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) NeuB PF03102.9 EIE86194.1 - 0.1 11.7 2.9 0.43 9.6 0.2 2.4 2 0 0 2 2 2 0 NeuB family RIX1 PF08167.7 EIE86195.1 - 5.1e-31 107.5 5.1 5.1e-31 107.5 3.5 2.5 2 0 0 2 2 2 2 rRNA processing/ribosome biogenesis DUF4358 PF14270.1 EIE86195.1 - 0.31 10.9 2.5 0.56 10.0 1.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4358) DPBB_1 PF03330.13 EIE86196.1 - 9.9e-16 57.5 0.8 5.2e-15 55.2 0.1 2.5 2 0 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EIE86196.1 - 3.7e-05 23.3 1.7 5e-05 22.9 0.6 1.7 1 1 0 1 1 1 1 Barwin family Imm47 PF15586.1 EIE86196.1 - 0.028 14.2 0.0 0.05 13.4 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 47 Tom37_C PF11801.3 EIE86196.1 - 0.058 13.2 1.0 0.1 12.4 0.7 1.3 1 0 0 1 1 1 0 Tom37 C-terminal domain NifU PF01106.12 EIE86196.1 - 0.071 12.8 0.1 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 NifU-like domain DUF912 PF06024.7 EIE86196.1 - 0.2 11.7 3.0 0.17 11.9 0.6 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) PH_10 PF15411.1 EIE86196.1 - 0.28 11.3 9.0 0.26 11.4 0.2 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain bZIP_1 PF00170.16 EIE86197.1 - 8.9e-08 31.9 14.4 1.2e-07 31.6 9.3 1.7 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EIE86197.1 - 1.5e-07 31.1 12.6 1.5e-07 31.1 8.7 2.2 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 EIE86197.1 - 0.2 11.9 11.5 0.2 11.9 7.0 1.7 1 1 1 2 2 2 0 bZIP Maf transcription factor AAA_23 PF13476.1 EIE86197.1 - 0.21 11.8 4.6 0.3 11.3 3.2 1.1 1 0 0 1 1 1 0 AAA domain NAM-associated PF14303.1 EIE86197.1 - 0.4 10.9 8.1 0.58 10.4 5.6 1.2 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain UQ_con PF00179.21 EIE86200.1 - 9.9e-38 128.7 0.0 1.8e-37 127.8 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Galactosyl_T PF01762.16 EIE86201.1 - 1.3e-13 51.0 0.1 2.2e-13 50.2 0.1 1.3 1 0 0 1 1 1 1 Galactosyltransferase EOS1 PF12326.3 EIE86201.1 - 1.2e-06 28.1 6.4 2.3e-06 27.3 4.4 1.4 1 0 0 1 1 1 1 N-glycosylation protein 7tm_2 PF00002.19 EIE86201.1 - 0.025 13.6 2.5 0.035 13.1 1.8 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (Secretin family) CTP_transf_2 PF01467.21 EIE86201.1 - 0.071 13.1 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Cytidylyltransferase DUF3796 PF12676.2 EIE86201.1 - 0.085 13.0 1.0 0.14 12.3 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3796) FAD_binding_2 PF00890.19 EIE86202.1 - 1.1e-52 179.3 0.4 1.7e-52 178.6 0.1 1.5 2 0 0 2 2 2 1 FAD binding domain Cyt-b5 PF00173.23 EIE86202.1 - 7.9e-24 83.2 0.0 3e-23 81.4 0.0 2.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain YfdX PF10938.3 EIE86202.1 - 0.051 13.2 0.2 0.093 12.3 0.1 1.3 1 0 0 1 1 1 0 YfdX protein Kinesin PF00225.18 EIE86203.1 - 5.7e-108 360.5 0.0 1.3e-107 359.3 0.0 1.6 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.3 EIE86203.1 - 1.1e-35 122.3 0.3 5.2e-35 120.1 0.0 2.3 2 0 0 2 2 2 1 Kinesin protein FHA PF00498.21 EIE86203.1 - 5.5e-08 32.8 0.0 1.3e-06 28.3 0.0 3.0 3 0 0 3 3 3 1 FHA domain KIF1B PF12423.3 EIE86203.1 - 0.00015 21.7 2.5 0.00016 21.6 0.5 2.1 2 0 0 2 2 2 1 Kinesin protein 1B Pterin_bind PF00809.17 EIE86203.1 - 0.02 14.3 0.1 0.052 12.9 0.1 1.7 1 0 0 1 1 1 0 Pterin binding enzyme Acyltransferase PF01553.16 EIE86204.1 - 0.0019 17.6 0.0 0.0063 15.9 0.0 1.9 1 1 0 1 1 1 1 Acyltransferase Metallophos PF00149.23 EIE86205.1 - 1.6e-38 132.1 0.7 2.5e-38 131.5 0.5 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF1647 PF07801.6 EIE86205.1 - 0.044 13.2 0.7 0.89 9.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1647) Mdv1 PF11542.3 EIE86206.1 - 0.16 11.9 0.3 0.37 10.7 0.0 1.7 2 0 0 2 2 2 0 Mitochondrial division protein 1 YtkA PF13115.1 EIE86207.1 - 0.051 13.9 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 YtkA-like S-methyl_trans PF02574.11 EIE86208.1 - 4.8e-94 315.0 0.0 1.3e-93 313.6 0.0 1.7 2 0 0 2 2 2 1 Homocysteine S-methyltransferase Met_synt_B12 PF02965.12 EIE86208.1 - 2.9e-75 252.1 0.0 6.3e-75 250.9 0.0 1.6 1 0 0 1 1 1 1 Vitamin B12 dependent methionine synthase, activation domain Pterin_bind PF00809.17 EIE86208.1 - 1.8e-42 145.1 0.3 6.5e-42 143.2 0.1 2.1 2 0 0 2 2 2 1 Pterin binding enzyme B12-binding PF02310.14 EIE86208.1 - 2.2e-18 66.2 0.4 2e-17 63.1 0.1 2.8 3 0 0 3 3 3 1 B12 binding domain B12-binding_2 PF02607.12 EIE86208.1 - 7.1e-08 32.3 0.3 5.2e-07 29.5 0.0 2.8 2 1 0 2 2 2 1 B12 binding domain Peptidase_M48 PF01435.13 EIE86209.1 - 7.2e-39 133.6 0.0 8.4e-39 133.4 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M13 PF01431.16 EIE86209.1 - 0.021 13.9 0.2 0.33 10.0 0.0 2.3 2 1 0 2 2 2 0 Peptidase family M13 HSP20 PF00011.16 EIE86210.1 - 5.7e-18 64.6 0.0 4.5e-16 58.5 0.0 2.1 1 1 0 1 1 1 1 Hsp20/alpha crystallin family DUF2320 PF10082.4 EIE86210.1 - 0.014 14.1 0.1 0.018 13.7 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2320) RasGAP PF00616.14 EIE86212.1 - 8.6e-26 90.8 0.8 2.6e-25 89.2 0.1 2.3 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.1 EIE86212.1 - 8.6e-19 67.9 0.8 4.1e-18 65.6 0.5 2.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain HEAT PF02985.17 EIE86212.1 - 5.2e-06 26.0 0.6 0.95 9.7 0.0 5.6 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.1 EIE86212.1 - 7.1e-05 23.0 0.4 2.2 8.6 0.0 5.2 5 1 1 6 6 6 3 HEAT repeats CRAL_TRIO PF00650.15 EIE86212.1 - 0.00055 19.4 0.1 0.0014 18.1 0.1 1.7 1 0 0 1 1 1 1 CRAL/TRIO domain TGT_C1 PF14809.1 EIE86212.1 - 0.051 13.4 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 C1 domain of tRNA-guanine transglycosylase dimerisation BTB_2 PF02214.17 EIE86214.1 - 0.04 14.1 0.0 0.53 10.5 0.0 2.5 2 1 0 2 2 2 0 BTB/POZ domain Arrestin_C PF02752.17 EIE86215.1 - 0.016 15.3 0.1 0.035 14.2 0.0 1.6 1 0 0 1 1 1 0 Arrestin (or S-antigen), C-terminal domain 2OG-FeII_Oxy_3 PF13640.1 EIE86216.1 - 6.9e-15 55.3 0.1 2e-14 53.8 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EIE86216.1 - 5.3e-06 25.9 0.2 1.4e-05 24.6 0.1 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily eIF2A PF08662.6 EIE86217.1 - 1.6e-36 125.8 8.7 1.1e-32 113.3 0.4 5.7 4 2 1 5 5 5 2 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 EIE86217.1 - 3.9e-05 23.3 3.0 0.0037 17.1 0.4 4.1 4 0 0 4 4 4 1 WD domain, G-beta repeat RRM_1 PF00076.17 EIE86217.1 - 8.7e-05 22.0 0.0 0.00021 20.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE86217.1 - 0.0044 16.9 0.0 0.012 15.6 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE86217.1 - 0.013 15.3 0.0 0.031 14.1 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DegQ PF08181.6 EIE86217.1 - 0.12 12.1 2.5 0.27 10.9 1.7 1.6 1 0 0 1 1 1 0 DegQ (SacQ) family HSP70 PF00012.15 EIE86218.1 - 6.9e-244 810.2 12.8 8e-244 810.0 8.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EIE86218.1 - 4.2e-18 65.0 2.7 3.7e-17 61.9 1.2 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 EIE86218.1 - 5.1e-05 22.9 0.0 0.00013 21.6 0.0 1.8 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 EIE86218.1 - 0.0039 17.0 9.7 0.043 13.6 0.0 4.0 3 3 0 3 3 3 2 Cell division protein FtsA DDR PF08841.5 EIE86218.1 - 0.012 14.4 1.8 0.098 11.4 1.0 2.3 1 1 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Asp_decarbox PF02261.11 EIE86218.1 - 0.024 14.2 0.1 0.071 12.6 0.0 1.9 2 0 0 2 2 2 0 Aspartate decarboxylase eIF3_N PF09440.5 EIE86218.1 - 0.047 13.8 6.8 0.02 15.0 2.7 1.9 2 0 0 2 2 2 0 eIF3 subunit 6 N terminal domain DAHP_synth_1 PF00793.15 EIE86219.1 - 2.7e-95 318.1 0.0 3.2e-95 317.9 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Herpes_UL51 PF04540.8 EIE86219.1 - 0.12 11.9 0.2 0.64 9.5 0.0 2.3 2 1 1 3 3 3 0 Herpesvirus UL51 protein Tom22 PF04281.8 EIE86220.1 - 2e-36 124.5 4.6 5.8e-36 123.0 3.2 1.7 1 1 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 BSMAP PF12280.3 EIE86220.1 - 0.15 11.8 0.7 0.17 11.7 0.0 1.5 2 0 0 2 2 2 0 Brain specific membrane anchored protein GvpG PF05120.7 EIE86220.1 - 0.56 10.0 0.1 0.56 10.0 0.1 2.7 3 0 0 3 3 3 0 Gas vesicle protein G ODC_AZ PF02100.12 EIE86221.1 - 1.7e-12 46.7 0.0 2e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme RtxA PF07634.6 EIE86222.1 - 0.18 12.1 0.6 0.48 10.8 0.1 1.9 2 0 0 2 2 2 0 RtxA repeat MDM31_MDM32 PF08118.6 EIE86223.1 - 7.5e-127 423.8 0.1 6.6e-72 242.5 0.0 2.5 2 1 0 2 2 2 2 Yeast mitochondrial distribution and morphology (MDM) proteins PH_9 PF15410.1 EIE86224.1 - 2.1e-14 53.7 0.0 2.1e-13 50.4 0.0 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EIE86224.1 - 7.1e-12 45.4 0.1 1.6e-09 37.8 0.0 3.5 2 2 1 3 3 3 1 PH domain U1snRNP70_N PF12220.3 EIE86224.1 - 0.00073 19.8 6.2 0.00085 19.6 0.2 3.3 3 0 0 3 3 3 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Phage_Gp23 PF10669.4 EIE86224.1 - 0.043 13.9 1.8 0.19 11.8 1.2 2.1 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) Cu_amine_oxid PF01179.15 EIE86226.1 - 5.2e-163 542.5 0.4 6.2e-163 542.3 0.3 1.0 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 EIE86226.1 - 1.7e-18 66.5 0.0 3.6e-18 65.4 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain EMP70 PF02990.11 EIE86227.1 - 0.08 11.3 2.2 0.1 11.0 1.5 1.0 1 0 0 1 1 1 0 Endomembrane protein 70 Closter_coat PF01785.12 EIE86229.1 - 0.0021 17.1 1.0 0.0038 16.2 0.7 1.7 1 1 0 1 1 1 1 Closterovirus coat protein zf-CpG_bind_C PF12269.3 EIE86229.1 - 0.069 12.6 2.5 0.15 11.5 1.7 1.6 1 0 0 1 1 1 0 CpG binding protein zinc finger C terminal domain eIF-4B PF06273.6 EIE86229.1 - 0.1 11.3 2.4 0.13 11.0 1.6 1.3 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B Mob_Pre PF01076.14 EIE86229.1 - 0.34 10.5 7.6 0.032 13.8 2.0 1.8 2 0 0 2 2 2 0 Plasmid recombination enzyme DUF45 PF01863.12 EIE86229.1 - 0.45 10.2 5.0 0.45 10.2 2.9 1.5 1 1 0 1 1 1 0 Protein of unknown function DUF45 EHN PF06441.7 EIE86229.1 - 0.56 10.1 3.7 0.27 11.1 0.5 1.9 2 1 0 2 2 2 0 Epoxide hydrolase N terminus FliD_C PF07195.7 EIE86229.1 - 0.59 9.3 14.5 0.46 9.7 8.4 2.0 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus DUF3584 PF12128.3 EIE86229.1 - 1.3 6.2 22.5 0.1 9.8 11.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) YkyA PF10368.4 EIE86229.1 - 1.3 8.3 16.7 0.024 13.9 6.8 1.5 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein DUF4600 PF15372.1 EIE86229.1 - 4 7.6 20.4 0.55 10.4 8.9 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4600) Ndc1_Nup PF09531.5 EIE86229.1 - 5.5 5.2 7.5 5.5 5.2 5.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Lipoprotein_3 PF00938.12 EIE86229.1 - 7.7 6.3 12.0 1 9.1 3.9 2.8 2 1 2 4 4 4 0 Lipoprotein RNA_pol_A_bac PF01000.21 EIE86232.1 - 1e-29 102.9 0.0 1.5e-29 102.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EIE86232.1 - 2.8e-09 35.9 0.0 3.3e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DAHP_synth_1 PF00793.15 EIE86233.1 - 2.5e-97 324.8 0.0 3.1e-97 324.5 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Methyltransf_26 PF13659.1 EIE86234.1 - 2.2e-09 37.3 0.0 2.9e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EIE86234.1 - 8.8e-05 21.9 0.0 0.00011 21.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 EIE86234.1 - 0.00061 19.4 0.0 0.0009 18.8 0.0 1.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 EIE86234.1 - 0.0053 17.5 0.0 0.0076 17.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIE86234.1 - 0.0077 16.6 0.0 0.011 16.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EIE86234.1 - 0.041 13.3 0.0 0.049 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 EIE86234.1 - 0.063 13.8 0.0 0.094 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EIE86234.1 - 0.1 13.0 0.0 0.14 12.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 EIE86234.1 - 0.13 12.6 0.0 0.2 12.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PH PF00169.24 EIE86235.1 - 0.069 13.3 1.0 0.5 10.6 0.7 2.2 1 1 0 1 1 1 0 PH domain DUF383 PF04063.9 EIE86237.1 - 3.2e-57 193.1 0.2 4.8e-57 192.6 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF383) Neurochondrin PF05536.6 EIE86237.1 - 0.0019 16.5 0.2 0.0027 16.1 0.1 1.2 1 0 0 1 1 1 1 Neurochondrin SecE PF00584.15 EIE86238.1 - 6.7e-13 48.0 0.0 8.3e-13 47.7 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex AA_permease_2 PF13520.1 EIE86239.1 - 2.4e-31 108.7 19.8 2.9e-31 108.4 13.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EIE86239.1 - 4.3e-14 51.7 16.6 5.4e-14 51.4 11.5 1.1 1 0 0 1 1 1 1 Amino acid permease PetG PF02529.10 EIE86239.1 - 0.74 9.3 2.9 3.4 7.2 0.3 2.5 2 0 0 2 2 2 0 Cytochrome B6-F complex subunit 5 DUF4131 PF13567.1 EIE86239.1 - 4.4 6.6 12.9 4.1 6.7 1.5 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) DUF373 PF04123.8 EIE86239.1 - 5.2 5.9 7.4 67 2.3 5.1 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF373) FSA_C PF10479.4 EIE86240.1 - 0.43 8.5 4.7 0.63 8.0 3.3 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Cellulase PF00150.13 EIE86241.1 - 1.8e-17 63.4 2.9 2.7e-17 62.8 2.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.10 EIE86241.1 - 0.0004 19.6 0.1 0.0029 16.7 0.0 2.0 2 0 0 2 2 2 1 Beta-galactosidase PIF1 PF05970.9 EIE86243.1 - 3.2e-14 52.6 0.1 4.3e-14 52.2 0.1 1.2 1 0 0 1 1 1 1 PIF1-like helicase Herpes_Helicase PF02689.9 EIE86243.1 - 3.8e-06 24.9 0.0 4.5e-06 24.7 0.0 1.0 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.1 EIE86243.1 - 0.0012 18.9 0.0 0.002 18.2 0.0 1.4 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain PseudoU_synth_2 PF00849.17 EIE86244.1 - 2.8e-30 105.3 0.3 3.5e-30 104.9 0.2 1.1 1 0 0 1 1 1 1 RNA pseudouridylate synthase Cpn60_TCP1 PF00118.19 EIE86245.1 - 1.4e-148 495.5 2.8 1.7e-148 495.2 1.9 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family IBN_N PF03810.14 EIE86246.1 - 2.8e-17 62.3 8.3 5.8e-13 48.5 0.2 4.3 4 0 0 4 4 4 3 Importin-beta N-terminal domain RIX1 PF08167.7 EIE86246.1 - 3e-06 26.9 0.9 0.028 14.0 0.1 3.3 2 2 2 4 4 4 2 rRNA processing/ribosome biogenesis Vac14_Fab1_bd PF12755.2 EIE86246.1 - 0.00042 20.6 0.4 0.017 15.4 0.2 3.6 2 1 1 3 3 3 1 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.1 EIE86246.1 - 0.00061 20.0 0.2 0.12 12.7 0.0 3.6 4 2 1 5 5 5 1 HEAT repeats DUF2435 PF10363.4 EIE86246.1 - 0.0032 17.3 1.3 0.016 15.0 0.4 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2435) HEAT PF02985.17 EIE86246.1 - 0.0037 17.2 0.2 0.15 12.1 0.0 3.9 3 0 0 3 3 3 1 HEAT repeat TFIIA PF03153.8 EIE86246.1 - 0.0096 15.8 8.1 0.015 15.2 5.6 1.4 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Ycf1 PF05758.7 EIE86246.1 - 0.044 11.5 5.7 0.064 10.9 4.0 1.2 1 0 0 1 1 1 0 Ycf1 CENP-T PF15511.1 EIE86246.1 - 0.34 10.0 13.0 0.59 9.3 9.0 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T BUD22 PF09073.5 EIE86246.1 - 0.61 9.0 20.2 1 8.3 14.0 1.2 1 0 0 1 1 1 0 BUD22 Cnd1 PF12717.2 EIE86246.1 - 0.85 9.4 12.3 0.098 12.5 1.1 3.6 3 1 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Astro_capsid PF03115.9 EIE86246.1 - 1.9 6.6 4.3 2.7 6.1 3.0 1.3 1 0 0 1 1 1 0 Astrovirus capsid protein precursor SDA1 PF05285.7 EIE86246.1 - 3.8 6.7 26.5 6.6 5.9 18.4 1.3 1 0 0 1 1 1 0 SDA1 AAA PF00004.24 EIE86247.1 - 5.8e-21 75.0 0.0 1.1e-20 74.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.6 EIE86247.1 - 5.4e-11 42.4 0.0 9.9e-11 41.5 0.0 1.4 1 0 0 1 1 1 1 BCS1 N terminal AAA_5 PF07728.9 EIE86247.1 - 1.8e-05 24.4 0.1 7e-05 22.5 0.0 2.1 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EIE86247.1 - 5.5e-05 23.2 0.0 0.00014 21.8 0.0 1.7 2 0 0 2 2 1 1 AAA ATPase domain AAA_17 PF13207.1 EIE86247.1 - 0.00021 22.0 0.7 0.0016 19.2 0.0 2.8 2 2 1 3 3 3 1 AAA domain AAA_24 PF13479.1 EIE86247.1 - 0.00038 20.1 0.2 0.015 14.9 0.0 2.7 3 0 0 3 3 3 1 AAA domain RuvB_N PF05496.7 EIE86247.1 - 0.00069 18.7 0.0 0.0012 17.9 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EIE86247.1 - 0.0011 19.1 0.0 0.0041 17.2 0.0 2.0 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.17 EIE86247.1 - 0.002 18.2 0.1 0.018 15.1 0.0 2.4 2 0 0 2 2 2 1 RNA helicase NACHT PF05729.7 EIE86247.1 - 0.0023 17.5 0.0 0.14 11.8 0.0 3.0 3 0 0 3 3 3 1 NACHT domain AAA_25 PF13481.1 EIE86247.1 - 0.0028 17.0 0.0 0.022 14.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 EIE86247.1 - 0.0041 16.2 0.0 0.011 14.8 0.0 1.8 2 0 0 2 2 2 1 KaiC AAA_11 PF13086.1 EIE86247.1 - 0.024 14.1 0.0 0.047 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EIE86247.1 - 0.028 14.7 0.1 0.15 12.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EIE86247.1 - 0.05 13.3 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain AAA_33 PF13671.1 EIE86247.1 - 0.072 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EIE86247.1 - 0.073 12.9 0.0 0.27 11.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.8 EIE86247.1 - 0.087 11.5 0.0 0.14 10.7 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus Rap_GAP PF02145.10 EIE86248.1 - 2.3e-06 27.0 0.0 2.6e-06 26.9 0.0 1.0 1 0 0 1 1 1 1 Rap/ran-GAP PHZA_PHZB PF03284.8 EIE86249.1 - 0.057 12.5 0.0 0.098 11.7 0.0 1.3 1 0 0 1 1 1 0 Phenazine biosynthesis protein A/B PAT1 PF09770.4 EIE86249.1 - 6.7 4.8 21.3 8.6 4.4 14.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DDE_1 PF03184.14 EIE86253.1 - 2.2e-24 85.8 1.0 1.3e-20 73.5 0.5 2.5 1 1 1 2 2 2 2 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EIE86253.1 - 2.1e-06 27.4 0.0 5.4e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.1 EIE86253.1 - 0.012 15.3 0.1 0.12 12.0 0.0 2.4 2 0 0 2 2 2 0 DDE superfamily endonuclease Retrotrans_gag PF03732.12 EIE86254.1 - 0.084 12.9 0.3 0.27 11.3 0.1 1.9 2 0 0 2 2 2 0 Retrotransposon gag protein Retrotrans_gag PF03732.12 EIE86258.1 - 3.8e-06 26.8 0.0 7.5e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein UBN2 PF14223.1 EIE86258.1 - 0.011 15.4 0.0 0.038 13.7 0.0 2.0 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type NtA PF03146.10 EIE86258.1 - 0.019 14.6 0.0 0.039 13.5 0.0 1.5 1 0 0 1 1 1 0 Agrin NtA domain Herpes_UL79 PF03049.9 EIE86258.1 - 0.11 11.4 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 UL79 family O-FucT PF10250.4 EIE86259.1 - 5.4e-16 58.6 0.0 6.9e-07 28.7 0.0 3.2 2 1 1 3 3 3 3 GDP-fucose protein O-fucosyltransferase ABC2_membrane PF01061.19 EIE86260.1 - 1e-85 286.1 56.9 1.5e-47 161.4 12.7 3.6 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.22 EIE86260.1 - 7.4e-37 126.7 0.0 3.1e-20 72.8 0.0 2.7 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EIE86260.1 - 1.9e-30 104.5 4.7 1.4e-23 82.4 0.0 2.8 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.1 EIE86260.1 - 2.8e-07 30.5 0.0 8.3e-07 29.0 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_21 PF13304.1 EIE86260.1 - 1.8e-06 28.1 0.0 0.17 11.8 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 EIE86260.1 - 4.8e-05 23.5 0.1 0.15 12.1 0.0 3.1 2 1 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.2 EIE86260.1 - 7.5e-05 21.9 60.9 0.00053 19.1 13.4 3.6 3 1 0 3 3 3 2 ABC-2 family transporter protein AAA_25 PF13481.1 EIE86260.1 - 9.3e-05 21.9 0.2 0.0055 16.1 0.1 2.7 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 EIE86260.1 - 0.00031 19.9 0.0 0.0046 16.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EIE86260.1 - 0.00035 20.0 1.7 0.01 15.3 0.2 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.1 EIE86260.1 - 0.00078 19.7 0.3 2 8.7 0.0 3.3 3 0 0 3 3 3 1 AAA domain cobW PF02492.14 EIE86260.1 - 0.0021 17.5 1.0 0.2 11.0 0.2 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 EIE86260.1 - 0.0031 18.3 0.3 1.5 9.6 0.0 3.4 4 0 0 4 4 2 1 AAA domain AAA_16 PF13191.1 EIE86260.1 - 0.0036 17.3 0.0 1 9.3 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_10 PF12846.2 EIE86260.1 - 0.0047 16.4 0.0 0.57 9.5 0.0 2.3 2 0 0 2 2 2 1 AAA-like domain PduV-EutP PF10662.4 EIE86260.1 - 0.0055 16.1 0.6 0.99 8.8 0.1 2.3 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation UPF0079 PF02367.12 EIE86260.1 - 0.0064 16.1 1.7 0.47 10.1 0.2 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_33 PF13671.1 EIE86260.1 - 0.014 15.2 0.0 0.72 9.7 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA_19 PF13245.1 EIE86260.1 - 0.018 14.7 1.7 6.5 6.5 0.3 2.6 2 0 0 2 2 2 0 Part of AAA domain AAA_28 PF13521.1 EIE86260.1 - 0.024 14.6 1.7 0.35 10.8 0.1 2.6 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EIE86260.1 - 0.035 13.7 0.3 2.4 7.7 0.2 2.5 2 0 0 2 2 2 0 NACHT domain Arch_ATPase PF01637.13 EIE86260.1 - 0.057 13.1 0.1 6.7 6.3 0.0 2.7 2 0 0 2 2 2 0 Archaeal ATPase AAA PF00004.24 EIE86260.1 - 0.061 13.5 0.5 19 5.4 0.1 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.1 EIE86260.1 - 0.076 12.9 0.0 0.42 10.5 0.0 2.2 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.1 EIE86260.1 - 0.097 12.2 0.9 6.1 6.3 0.2 2.4 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 EIE86260.1 - 0.11 12.2 0.7 13 5.4 0.0 3.1 3 0 0 3 3 3 0 NTPase Miro PF08477.8 EIE86260.1 - 0.12 12.9 0.0 5.9 7.4 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein MMR_HSR1 PF01926.18 EIE86260.1 - 0.13 12.2 0.1 20 5.1 0.0 3.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase PDR_assoc PF08370.6 EIE86260.1 - 3.4 7.2 10.1 0.087 12.3 0.2 3.4 3 0 0 3 3 3 0 Plant PDR ABC transporter associated ICMT PF04140.9 EIE86261.1 - 2.6e-14 53.1 0.0 3e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EIE86261.1 - 6.5e-05 22.9 0.1 7.3e-05 22.8 0.1 1.0 1 0 0 1 1 1 1 Phospholipid methyltransferase NnrU PF07298.6 EIE86261.1 - 0.047 13.0 0.2 0.05 12.9 0.1 1.1 1 0 0 1 1 1 0 NnrU protein DUF1230 PF06799.6 EIE86261.1 - 0.09 12.6 0.2 0.096 12.5 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1230) Ist1 PF03398.9 EIE86262.1 - 2e-59 199.6 3.4 2e-59 199.6 2.4 2.2 2 0 0 2 2 2 1 Regulator of Vps4 activity in the MVB pathway zf-RING_4 PF14570.1 EIE86262.1 - 3.1e-19 68.2 11.4 6.7e-19 67.2 7.9 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.1 EIE86262.1 - 2e-05 24.1 8.1 4.5e-05 23.0 5.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.17 EIE86262.1 - 7.5e-05 22.2 0.0 0.0012 18.3 0.0 2.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE86262.1 - 8.9e-05 22.2 0.1 0.00058 19.6 0.1 2.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Trp_syntA PF00290.15 EIE86263.1 - 1.7e-66 223.3 0.0 3.2e-66 222.5 0.0 1.4 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.20 EIE86263.1 - 3.3e-44 151.3 0.5 6.5e-44 150.3 0.4 1.5 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Kei1 PF08552.6 EIE86264.1 - 0.47 10.0 2.6 0.97 9.0 1.9 1.6 1 1 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Band_7 PF01145.20 EIE86266.1 - 8.6e-29 100.7 0.5 1.3e-28 100.1 0.3 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 EIE86266.1 - 0.031 13.8 0.1 0.049 13.1 0.1 1.3 1 0 0 1 1 1 0 SPFH domain-Band 7 family Band_7 PF01145.20 EIE86267.1 - 2.7e-27 95.8 0.1 3.6e-27 95.4 0.1 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 EIE86267.1 - 0.0097 15.4 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 SPFH domain-Band 7 family ATP-synt_ab_C PF00306.22 EIE86269.1 - 7.8e-25 87.5 1.3 1e-24 87.1 0.9 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab PF00006.20 EIE86269.1 - 4.3e-15 55.7 0.2 1.1e-14 54.4 0.0 1.7 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain DDE_3 PF13358.1 EIE86270.1 - 4.2e-10 39.5 0.0 2.9e-09 36.8 0.0 2.0 1 1 0 1 1 1 1 DDE superfamily endonuclease Kinesin PF00225.18 EIE86271.1 - 5.2e-48 163.4 6.7 3.8e-46 157.3 2.9 3.6 2 2 1 3 3 3 2 Kinesin motor domain TMF_DNA_bd PF12329.3 EIE86271.1 - 0.0063 16.2 7.4 0.0063 16.2 5.1 6.8 5 2 1 7 7 7 2 TATA element modulatory factor 1 DNA binding PET PF06297.9 EIE86271.1 - 0.061 12.9 1.4 0.19 11.4 1.0 1.8 1 0 0 1 1 1 0 PET Domain IncA PF04156.9 EIE86271.1 - 0.24 10.9 70.6 1.3 8.5 15.8 5.2 2 1 2 4 4 4 0 IncA protein BBP1_C PF15272.1 EIE86272.1 - 0.0075 15.8 1.1 0.01 15.4 0.8 1.1 1 0 0 1 1 1 1 Spindle pole body component BBP1, C-terminal Inhibitor_I78 PF11720.3 EIE86273.1 - 1.7e-12 46.8 0.0 1.8e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.13 EIE86273.1 - 0.00028 20.9 0.0 0.00041 20.4 0.0 1.4 1 0 0 1 1 1 1 Potato inhibitor I family Acetyltransf_1 PF00583.19 EIE86275.1 - 4.4e-18 65.0 0.0 6.4e-18 64.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EIE86275.1 - 1.5e-13 50.6 0.0 2.2e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EIE86275.1 - 4.1e-10 39.8 0.0 5.4e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EIE86275.1 - 1.5e-07 31.5 0.0 1.9e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EIE86275.1 - 4e-07 30.0 0.0 5.2e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EIE86275.1 - 8.5e-07 28.7 0.0 1.6e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 EIE86275.1 - 1.3e-05 24.8 0.0 2.5e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 EIE86275.1 - 7.7e-05 22.8 0.0 9.6e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EIE86275.1 - 0.01 15.6 0.0 0.026 14.3 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DHDPS PF00701.17 EIE86276.1 - 1.1e-51 175.1 0.0 1.4e-51 174.7 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family DUF3349 PF11829.3 EIE86276.1 - 0.13 12.6 0.0 14 6.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3349) DDE_3 PF13358.1 EIE86277.1 - 0.00014 21.6 0.0 0.023 14.4 0.0 2.1 1 1 1 2 2 2 2 DDE superfamily endonuclease DUF4452 PF14618.1 EIE86278.1 - 1.3e-05 25.0 8.0 3.2e-05 23.7 5.5 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4452) Glyco_transf_8C PF08437.5 EIE86278.1 - 0.092 12.7 3.6 0.26 11.3 0.3 2.8 2 1 1 3 3 3 0 Glycosyl transferase family 8 C-terminal Hexapep PF00132.19 EIE86279.1 - 7.6e-08 31.5 13.4 0.0083 15.5 1.1 4.4 2 1 2 4 4 4 3 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.18 EIE86279.1 - 1.1e-07 31.4 0.0 6e-07 29.0 0.0 2.0 2 0 0 2 2 2 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 EIE86279.1 - 1.5e-07 31.6 0.0 2.6e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain rve PF00665.21 EIE86280.1 - 2e-23 82.7 0.0 4.7e-23 81.5 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE86280.1 - 1.4e-15 57.2 0.3 4e-15 55.7 0.2 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE86280.1 - 4.1e-11 42.3 1.1 9.6e-11 41.1 0.7 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.12 EIE86280.1 - 0.00062 19.7 1.2 0.0031 17.5 0.8 2.3 1 0 0 1 1 1 1 Retrotransposon gag protein zf-H2C2 PF09337.5 EIE86280.1 - 0.0015 17.9 0.1 0.0041 16.4 0.1 1.9 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Asp_protease_2 PF13650.1 EIE86280.1 - 0.0042 17.5 0.2 0.011 16.2 0.2 1.8 1 0 0 1 1 1 1 Aspartyl protease rve_3 PF13683.1 EIE86280.1 - 0.0073 15.8 0.1 0.05 13.1 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain UBN2_2 PF14227.1 EIE86280.1 - 0.0097 15.4 4.9 0.036 13.6 0.0 3.4 3 0 0 3 3 3 1 gag-polypeptide of LTR copia-type Asp_protease PF09668.5 EIE86280.1 - 0.043 13.3 0.1 0.13 11.8 0.1 1.8 1 1 0 1 1 1 0 Aspartyl protease zf-CCCH PF00642.19 EIE86281.1 - 3e-20 71.4 22.4 3.9e-12 45.5 1.9 2.9 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EIE86281.1 - 0.0068 16.3 15.3 0.073 13.0 0.6 3.2 3 1 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type DUF1510 PF07423.6 EIE86281.1 - 0.028 13.8 9.3 0.077 12.3 6.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) BHD_1 PF10403.4 EIE86281.1 - 0.25 10.9 2.6 0.55 9.7 1.0 2.1 2 0 0 2 2 2 0 Rad4 beta-hairpin domain 1 zf-CCHH PF10283.4 EIE86281.1 - 0.46 10.3 9.5 1 9.2 0.4 3.4 3 0 0 3 3 3 0 Zinc-finger (CX5CX6HX5H) motif PMR5N PF14416.1 EIE86281.1 - 0.9 9.6 5.1 3.5 7.7 0.5 2.7 1 1 1 2 2 2 0 PMR5 N terminal Domain HIT PF01230.18 EIE86282.1 - 6.7e-10 39.3 0.2 9.6e-10 38.8 0.1 1.2 1 0 0 1 1 1 1 HIT domain LEA_2 PF03168.8 EIE86283.1 - 1.7e-09 37.9 0.1 2.4e-09 37.4 0.1 1.2 1 0 0 1 1 1 1 Late embryogenesis abundant protein FIIND PF13553.1 EIE86283.1 - 0.072 12.5 0.0 0.087 12.2 0.0 1.1 1 0 0 1 1 1 0 Function to find SWIRM PF04433.12 EIE86284.1 - 1e-30 105.6 0.0 1e-30 105.6 0.0 2.8 3 1 1 4 4 4 1 SWIRM domain Myb_DNA-binding PF00249.26 EIE86284.1 - 3e-08 33.5 0.0 7.3e-08 32.3 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EIE86284.1 - 1e-05 25.5 0.0 4.2e-05 23.5 0.0 2.1 1 0 0 1 1 1 1 Myb-like DNA-binding domain Lar_restr_allev PF14354.1 EIE86284.1 - 0.18 12.1 1.1 0.47 10.7 0.8 1.7 1 0 0 1 1 1 0 Restriction alleviation protein Lar Med15 PF09606.5 EIE86284.1 - 3.9 5.5 50.4 5.7 5.0 34.9 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Ribonucleas_3_3 PF14622.1 EIE86285.1 - 9.9e-22 77.2 0.2 1.6e-21 76.6 0.1 1.4 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 EIE86285.1 - 0.0013 19.1 0.1 0.0018 18.7 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease III domain FAM183 PF14886.1 EIE86285.1 - 0.004 17.6 0.2 0.006 17.0 0.2 1.2 1 0 0 1 1 1 1 FAM183A and FAM183B related HTH_30 PF13556.1 EIE86285.1 - 0.042 13.4 0.0 0.85 9.2 0.0 2.2 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain Fer4 PF00037.22 EIE86286.1 - 2.2e-14 52.3 16.5 1.5e-08 33.8 3.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 EIE86286.1 - 2.7e-12 46.8 10.8 4.2e-12 46.2 7.5 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.1 EIE86286.1 - 4.4e-10 40.1 6.7 0.00012 22.7 0.2 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.1 EIE86286.1 - 4.4e-10 39.2 3.9 8.1e-05 22.3 0.2 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 EIE86286.1 - 8.2e-10 38.3 22.8 5.2e-08 32.5 8.9 1.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 EIE86286.1 - 2.4e-09 37.3 11.1 4.1e-09 36.5 7.7 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 EIE86286.1 - 9.9e-09 35.1 29.2 1.2e-05 25.1 8.0 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_2 PF12797.2 EIE86286.1 - 1.5e-08 34.0 14.4 8.2e-05 22.3 1.8 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.2 EIE86286.1 - 6.3e-08 32.1 18.0 0.00064 19.4 3.4 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 EIE86286.1 - 3.1e-06 27.4 9.0 0.00043 20.5 7.5 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_4 PF12800.2 EIE86286.1 - 3.1e-06 27.0 12.6 0.00069 19.7 2.3 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_18 PF13746.1 EIE86286.1 - 1.2e-05 25.5 10.0 0.0052 17.1 0.6 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.1 EIE86286.1 - 5.5e-05 23.4 10.4 0.023 15.1 0.2 2.4 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_15 PF13459.1 EIE86286.1 - 0.0066 16.9 13.0 0.42 11.2 1.5 2.6 2 1 0 2 2 2 2 4Fe-4S single cluster domain Fer4_3 PF12798.2 EIE86286.1 - 0.033 14.7 18.1 0.069 13.7 3.2 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.5 EIE86286.1 - 0.13 12.3 5.7 0.32 11.1 0.1 2.3 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Ribosomal_S5_C PF03719.10 EIE86287.1 - 2e-24 84.6 0.1 2.2e-23 81.2 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 EIE86287.1 - 1.8e-13 49.9 0.2 3.5e-13 49.0 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Fungal_trans PF04082.13 EIE86288.1 - 2.7e-25 88.7 1.1 4e-25 88.1 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain CBS PF00571.23 EIE86289.1 - 3.9e-32 109.7 1.4 2.8e-09 36.6 0.1 4.7 4 1 0 4 4 4 4 CBS domain DsrD PF08679.6 EIE86291.1 - 0.17 11.9 2.5 1.8 8.6 1.6 2.3 1 1 0 1 1 1 0 Dissimilatory sulfite reductase D (DsrD) NMO PF03060.10 EIE86292.1 - 6e-67 226.1 0.5 7.7e-67 225.7 0.3 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EIE86292.1 - 6.2e-12 45.0 1.5 1.6e-08 33.8 1.0 2.4 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NanE PF04131.9 EIE86292.1 - 0.0029 16.5 2.4 0.0057 15.6 0.1 2.4 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase FMN_dh PF01070.13 EIE86292.1 - 0.0072 15.2 1.0 0.014 14.2 0.7 1.5 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 EIE86292.1 - 0.049 12.5 2.4 0.07 12.0 0.5 2.1 2 1 0 2 2 2 0 Conserved region in glutamate synthase His_biosynth PF00977.16 EIE86292.1 - 0.06 12.6 0.1 0.14 11.3 0.1 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein Mito_carr PF00153.22 EIE86293.1 - 3.2e-30 103.6 1.4 9.9e-16 57.2 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein APG6 PF04111.7 EIE86294.1 - 0.069 12.1 8.9 0.098 11.6 6.2 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 EIE86294.1 - 0.079 12.5 9.5 0.12 11.9 6.6 1.3 1 0 0 1 1 1 0 IncA protein Syntaxin-6_N PF09177.6 EIE86294.1 - 0.12 12.7 5.1 0.1 12.9 0.6 2.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Spc7 PF08317.6 EIE86294.1 - 0.13 10.9 11.9 0.079 11.6 1.3 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein Filament PF00038.16 EIE86294.1 - 0.36 10.2 9.4 0.11 11.9 0.6 2.1 1 1 1 2 2 2 0 Intermediate filament protein DUF4094 PF13334.1 EIE86294.1 - 1.7 9.1 6.4 4.8 7.6 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) Prefoldin PF02996.12 EIE86294.1 - 2 8.0 8.8 7.8 6.1 0.0 3.5 1 1 3 4 4 4 0 Prefoldin subunit TPR_MLP1_2 PF07926.7 EIE86294.1 - 3.7 7.3 11.5 6.5 6.5 8.0 1.4 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Mnd1 PF03962.10 EIE86294.1 - 8.1 6.0 8.6 18 4.9 3.9 2.1 1 1 1 2 2 2 0 Mnd1 family DUF262 PF03235.9 EIE86295.1 - 4.7e-11 43.0 0.9 4.7e-11 43.0 0.6 2.3 2 1 0 2 2 2 1 Protein of unknown function DUF262 AAA_12 PF13087.1 EIE86296.1 - 1.4e-38 132.2 0.0 3.6e-38 130.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EIE86296.1 - 4.2e-26 91.9 0.0 7.4e-26 91.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 EIE86296.1 - 1.1e-06 28.4 0.0 0.0035 16.9 0.0 3.2 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.1 EIE86296.1 - 3.3e-05 23.9 0.0 0.00014 21.9 0.0 2.1 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Septin PF00735.13 EIE86297.1 - 4.9e-120 399.7 0.8 4.9e-120 399.7 0.6 1.9 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 EIE86297.1 - 2.7e-07 30.5 0.0 2.7e-07 30.5 0.0 2.4 3 0 0 3 3 3 1 50S ribosome-binding GTPase DUF258 PF03193.11 EIE86297.1 - 1.1e-05 24.6 2.0 2.5e-05 23.5 0.1 2.4 1 1 1 2 2 2 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EIE86297.1 - 4e-05 23.1 0.4 0.0016 17.8 0.0 2.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AIG1 PF04548.11 EIE86297.1 - 0.0016 17.6 0.0 0.0016 17.6 0.0 2.1 2 1 0 2 2 2 1 AIG1 family Ras PF00071.17 EIE86297.1 - 0.0031 16.9 0.0 0.0084 15.5 0.0 1.7 1 0 0 1 1 1 1 Ras family AAA_10 PF12846.2 EIE86297.1 - 0.0032 16.9 0.1 0.0071 15.8 0.0 1.7 2 0 0 2 2 2 1 AAA-like domain ABC_tran PF00005.22 EIE86297.1 - 0.0036 17.6 1.8 0.023 15.0 0.0 2.4 2 0 0 2 2 2 1 ABC transporter Miro PF08477.8 EIE86297.1 - 0.0037 17.7 1.5 0.01 16.3 0.0 2.6 3 1 0 3 3 2 1 Miro-like protein AAA_22 PF13401.1 EIE86297.1 - 0.0059 16.7 0.2 0.042 13.9 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EIE86297.1 - 0.0098 15.8 0.3 0.034 14.1 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain Dynamin_N PF00350.18 EIE86297.1 - 0.011 15.5 5.9 2 8.2 0.0 3.5 2 1 1 3 3 3 0 Dynamin family RNA_helicase PF00910.17 EIE86297.1 - 0.022 14.9 1.2 1.3 9.2 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Arch_ATPase PF01637.13 EIE86297.1 - 0.034 13.8 6.7 0.077 12.6 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase AAA_29 PF13555.1 EIE86297.1 - 0.043 13.3 0.0 0.08 12.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain FeoB_N PF02421.13 EIE86297.1 - 0.043 13.0 0.1 0.12 11.6 0.1 1.8 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_24 PF13479.1 EIE86297.1 - 0.083 12.4 1.8 0.46 10.0 0.0 2.6 2 1 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 EIE86297.1 - 6 6.3 7.9 23 4.4 0.1 3.8 2 2 0 3 3 3 0 Conserved hypothetical ATP binding protein Pkinase PF00069.20 EIE86302.1 - 1.4e-64 217.7 0.6 2.1e-64 217.2 0.4 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE86302.1 - 1.5e-34 119.2 0.4 2.1e-34 118.7 0.3 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE86302.1 - 0.00012 21.1 0.0 0.00019 20.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Hexokinase_2 PF03727.11 EIE86303.1 - 1.1e-74 250.7 1.7 1.4e-74 250.3 1.2 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EIE86303.1 - 9.7e-56 188.3 0.0 1.6e-55 187.6 0.0 1.4 1 0 0 1 1 1 1 Hexokinase DUF4434 PF14488.1 EIE86303.1 - 0.1 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4434) ABC_tran PF00005.22 EIE86304.1 - 8.7e-39 132.9 0.0 2.8e-21 76.2 0.0 2.5 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EIE86304.1 - 3.9e-18 66.4 4.8 2.9e-05 24.2 0.2 4.2 2 2 0 3 3 3 3 AAA domain AAA_22 PF13401.1 EIE86304.1 - 1e-08 35.3 0.1 0.00036 20.6 0.0 3.2 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EIE86304.1 - 3.2e-07 29.7 0.0 0.0019 17.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 EIE86304.1 - 1.7e-06 27.4 0.1 0.37 9.9 0.0 3.5 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 EIE86304.1 - 5.2e-06 25.7 0.0 0.042 13.0 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 EIE86304.1 - 2e-05 25.3 0.0 0.48 11.2 0.0 3.6 4 0 0 4 4 3 2 AAA domain SbcCD_C PF13558.1 EIE86304.1 - 3.5e-05 23.6 0.0 0.72 9.8 0.0 3.2 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 EIE86304.1 - 4.8e-05 23.7 0.3 0.021 15.1 0.0 2.9 4 0 0 4 4 2 1 AAA domain Dynamin_N PF00350.18 EIE86304.1 - 5.9e-05 22.9 0.1 0.0016 18.2 0.0 2.8 3 0 0 3 3 2 1 Dynamin family AAA_28 PF13521.1 EIE86304.1 - 8.9e-05 22.5 0.5 0.52 10.2 0.0 3.1 4 0 0 4 4 2 2 AAA domain AAA_14 PF13173.1 EIE86304.1 - 0.00012 21.9 0.0 0.19 11.5 0.0 3.1 3 1 0 3 3 3 1 AAA domain AAA_33 PF13671.1 EIE86304.1 - 0.00015 21.6 2.4 0.76 9.6 0.0 3.4 2 1 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 EIE86304.1 - 0.00015 21.6 0.0 0.34 10.8 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase IstB_IS21 PF01695.12 EIE86304.1 - 0.00025 20.4 0.3 3.9 6.8 0.0 3.4 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_25 PF13481.1 EIE86304.1 - 0.0008 18.8 1.0 0.65 9.3 0.1 3.2 2 2 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EIE86304.1 - 0.00099 19.4 1.0 8 6.7 0.0 3.9 4 0 0 4 4 4 0 AAA domain PduV-EutP PF10662.4 EIE86304.1 - 0.0013 18.2 0.0 1.9 7.9 0.0 2.5 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 EIE86304.1 - 0.0024 17.6 0.0 1.4 8.6 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 EIE86304.1 - 0.003 17.7 0.0 6.1 7.0 0.0 3.5 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Miro PF08477.8 EIE86304.1 - 0.0032 17.9 0.0 3.9 8.0 0.0 2.9 2 0 0 2 2 2 1 Miro-like protein cobW PF02492.14 EIE86304.1 - 0.005 16.2 0.0 0.44 9.9 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_PrkA PF08298.6 EIE86304.1 - 0.0074 15.0 0.0 0.044 12.4 0.0 2.0 2 0 0 2 2 2 1 PrkA AAA domain T2SE PF00437.15 EIE86304.1 - 0.0087 14.9 0.0 1.6 7.5 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein NACHT PF05729.7 EIE86304.1 - 0.0098 15.5 0.2 0.89 9.1 0.0 3.2 3 0 0 3 3 3 1 NACHT domain AAA_16 PF13191.1 EIE86304.1 - 0.011 15.7 1.0 4.1 7.3 0.0 3.0 2 1 0 2 2 2 0 AAA ATPase domain AAA_15 PF13175.1 EIE86304.1 - 0.013 14.5 0.0 3 6.8 0.0 3.5 4 0 0 4 4 4 0 AAA ATPase domain AAA_10 PF12846.2 EIE86304.1 - 0.016 14.7 0.0 5.2 6.4 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain GTP_EFTU PF00009.22 EIE86304.1 - 0.029 13.8 0.0 0.77 9.1 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_24 PF13479.1 EIE86304.1 - 0.036 13.6 0.0 1.5 8.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EIE86304.1 - 0.058 12.4 0.0 3.2 6.7 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_19 PF13245.1 EIE86304.1 - 0.081 12.6 0.3 20 4.9 0.0 2.7 2 0 0 2 2 2 0 Part of AAA domain RNA_helicase PF00910.17 EIE86304.1 - 0.12 12.5 0.0 16 5.6 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Mg_chelatase PF01078.16 EIE86304.1 - 0.12 11.4 0.0 16 4.5 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_30 PF13604.1 EIE86304.1 - 0.14 11.7 3.9 8.4 5.9 0.0 3.1 4 0 0 4 4 3 0 AAA domain NTPase_1 PF03266.10 EIE86304.1 - 0.19 11.4 1.2 32 4.1 0.0 3.4 3 0 0 3 3 3 0 NTPase ETF_alpha PF00766.14 EIE86305.1 - 3e-38 129.3 1.7 5.3e-38 128.5 0.3 2.1 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain ETF PF01012.16 EIE86305.1 - 3e-38 131.0 4.5 3e-38 131.0 3.1 1.7 2 0 0 2 2 2 1 Electron transfer flavoprotein domain p450 PF00067.17 EIE86306.1 - 4e-81 272.9 0.2 4.9e-81 272.5 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 TroA PF01297.12 EIE86306.1 - 0.012 14.9 0.3 0.02 14.1 0.2 1.3 1 0 0 1 1 1 0 Periplasmic solute binding protein family Adeno_terminal PF02459.10 EIE86306.1 - 0.12 10.5 0.0 0.17 10.0 0.0 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein Tim17 PF02466.14 EIE86307.1 - 7.6e-07 29.2 0.3 8.3e-07 29.1 0.2 1.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family V4R PF02830.13 EIE86307.1 - 0.015 15.1 0.1 0.02 14.7 0.1 1.1 1 0 0 1 1 1 0 V4R domain Pkinase PF00069.20 EIE86308.1 - 1.6e-70 237.2 0.0 8.3e-70 234.8 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE86308.1 - 1.3e-33 116.1 0.7 1e-30 106.6 0.0 3.6 2 2 1 3 3 3 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE86308.1 - 1.5e-06 27.3 1.6 0.016 14.1 0.0 2.7 2 1 0 2 2 2 2 Kinase-like RIO1 PF01163.17 EIE86308.1 - 4.5e-05 22.8 1.1 0.0001 21.6 0.8 1.6 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EIE86308.1 - 0.14 11.8 0.0 2.8 7.6 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family DASH_Ask1 PF08655.5 EIE86309.1 - 1.8e-16 59.7 0.4 3.4e-16 58.8 0.3 1.5 1 0 0 1 1 1 1 DASH complex subunit Ask1 p450 PF00067.17 EIE86310.1 - 1.1e-37 129.6 0.4 1.2e-23 83.4 0.0 2.2 1 1 1 2 2 2 2 Cytochrome P450 EzrA PF06160.7 EIE86310.1 - 0.07 11.3 0.1 4.3 5.3 0.0 2.1 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA Iso_dh PF00180.15 EIE86311.1 - 2.7e-97 325.8 0.0 8.8e-97 324.1 0.0 1.6 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Arm PF00514.18 EIE86312.1 - 3.8e-90 293.0 14.8 6.8e-14 51.0 0.0 8.6 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EIE86312.1 - 1.2e-25 89.6 0.1 2.1e-10 40.7 0.0 6.3 2 1 5 7 7 7 6 HEAT repeats HEAT_EZ PF13513.1 EIE86312.1 - 1.4e-21 76.2 2.0 5.2e-07 29.9 0.0 6.2 6 1 1 7 7 6 4 HEAT-like repeat HEAT PF02985.17 EIE86312.1 - 2.2e-18 64.5 1.7 2.9e-05 23.7 0.0 7.0 7 1 0 7 7 7 3 HEAT repeat IBB PF01749.15 EIE86312.1 - 1.2e-17 63.8 7.8 2.3e-17 62.9 5.4 1.5 1 0 0 1 1 1 1 Importin beta binding domain Arm_2 PF04826.8 EIE86312.1 - 1.9e-10 40.3 0.1 0.0028 16.7 0.0 4.0 2 1 2 4 4 4 4 Armadillo-like Adaptin_N PF01602.15 EIE86312.1 - 4.1e-06 25.4 0.0 2e-05 23.1 0.0 2.0 1 1 1 2 2 2 1 Adaptin N terminal region V-ATPase_H_C PF11698.3 EIE86312.1 - 1.8e-05 24.6 0.0 0.19 11.6 0.0 4.5 3 2 1 4 4 4 1 V-ATPase subunit H Proteasom_PSMB PF10508.4 EIE86312.1 - 8e-05 21.1 0.2 0.0037 15.6 0.0 2.5 2 0 0 2 2 2 1 Proteasome non-ATPase 26S subunit HEAT_PBS PF03130.11 EIE86312.1 - 0.0021 18.3 0.6 0.56 10.8 0.1 3.9 3 0 0 3 3 3 1 PBS lyase HEAT-like repeat RICTOR_V PF14668.1 EIE86312.1 - 0.016 15.0 6.2 1 9.3 0.0 4.7 3 3 2 5 5 5 0 Rapamycin-insensitive companion of mTOR, domain 5 Sec7 PF01369.15 EIE86313.1 - 1.9e-26 92.9 7.8 7e-26 91.0 0.4 3.2 3 0 0 3 3 3 2 Sec7 domain PH PF00169.24 EIE86313.1 - 4.5e-05 23.5 0.1 0.18 11.9 0.0 3.0 2 0 0 2 2 2 2 PH domain PH_10 PF15411.1 EIE86313.1 - 0.00022 21.3 0.1 0.0013 18.9 0.1 2.3 1 0 0 1 1 1 1 Pleckstrin homology domain COX7C PF02935.11 EIE86314.1 - 5.6e-15 54.8 0.0 6e-15 54.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc Saccharop_dh PF03435.13 EIE86315.1 - 5.7e-115 384.3 0.1 6.5e-115 384.1 0.1 1.0 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 EIE86315.1 - 5.5e-07 29.7 0.1 1.1e-06 28.7 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 EIE86315.1 - 0.00015 22.1 0.4 0.00046 20.5 0.1 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent adh_short PF00106.20 EIE86315.1 - 0.00029 20.7 0.2 0.0034 17.3 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EIE86315.1 - 0.00039 20.4 0.2 0.00085 19.3 0.0 1.6 2 0 0 2 2 2 1 NADH(P)-binding Semialdhyde_dh PF01118.19 EIE86315.1 - 0.00041 20.6 0.1 0.00086 19.5 0.1 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 EIE86315.1 - 0.0022 17.4 0.0 0.0037 16.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_3 PF03447.11 EIE86315.1 - 0.0078 16.6 0.3 0.016 15.5 0.0 1.6 2 0 0 2 2 1 1 Homoserine dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EIE86315.1 - 0.0083 14.8 0.0 0.014 14.1 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 EIE86315.1 - 0.0086 15.3 0.0 0.015 14.5 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family KR PF08659.5 EIE86315.1 - 0.025 14.2 0.1 0.058 13.0 0.0 1.7 2 0 0 2 2 2 0 KR domain GFO_IDH_MocA PF01408.17 EIE86315.1 - 0.072 13.6 0.3 0.18 12.2 0.1 1.8 2 0 0 2 2 1 0 Oxidoreductase family, NAD-binding Rossmann fold Glyco_hydro_45 PF02015.11 EIE86317.1 - 3e-85 285.3 23.5 3e-85 285.3 16.3 1.8 2 1 0 2 2 2 1 Glycosyl hydrolase family 45 CBM_1 PF00734.13 EIE86317.1 - 1.6e-11 43.6 8.4 1.6e-11 43.6 5.8 3.3 3 0 0 3 3 3 1 Fungal cellulose binding domain Mitofilin PF09731.4 EIE86317.1 - 0.013 14.1 4.8 0.016 13.8 3.3 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein SAPS PF04499.10 EIE86317.1 - 0.35 9.4 4.0 0.41 9.2 2.8 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Atrophin-1 PF03154.10 EIE86317.1 - 1.9 6.5 10.2 2.2 6.2 7.0 1.1 1 0 0 1 1 1 0 Atrophin-1 family Macoilin PF09726.4 EIE86317.1 - 2.8 6.1 16.8 3.4 5.8 11.7 1.1 1 0 0 1 1 1 0 Transmembrane protein SRP-alpha_N PF04086.8 EIE86317.1 - 3.6 6.9 14.2 5.2 6.3 9.8 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF2413 PF10310.4 EIE86317.1 - 3.6 6.2 17.8 5.1 5.7 12.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Med3 PF11593.3 EIE86317.1 - 3.7 6.6 19.2 4.8 6.3 13.3 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal RVP_2 PF08284.6 EIE86319.1 - 0.014 15.3 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 Retroviral aspartyl protease Grp1_Fun34_YaaH PF01184.14 EIE86320.1 - 1.9e-30 105.7 17.5 2.2e-30 105.5 12.2 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Bromo_TP PF07524.8 EIE86321.1 - 0.011 15.4 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Mtp PF03821.11 EIE86321.1 - 0.11 11.8 0.1 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Golgi 4-transmembrane spanning transporter Phosphodiest PF01663.17 EIE86322.1 - 2.7e-67 227.6 4.3 3.7e-67 227.2 3.0 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EIE86322.1 - 9.5e-05 21.7 0.2 0.02 14.0 0.1 2.3 1 1 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 EIE86322.1 - 0.0038 16.6 0.0 0.0064 15.9 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Solute_trans_a PF03619.11 EIE86323.1 - 6.1e-53 179.8 10.6 8.6e-53 179.4 7.3 1.2 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Glyoxal_oxid_N PF07250.6 EIE86324.1 - 1.1e-41 142.5 0.0 3.9e-40 137.4 0.0 2.2 2 1 0 2 2 2 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 EIE86324.1 - 1.9e-21 75.9 0.3 3e-21 75.3 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.1 EIE86324.1 - 0.00031 20.4 0.1 0.9 9.3 0.0 3.2 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.1 EIE86324.1 - 0.0088 16.1 0.1 8.6 6.7 0.0 4.2 4 0 0 4 4 4 1 Kelch motif Kelch_2 PF07646.10 EIE86324.1 - 0.1 12.4 0.0 5.2 7.0 0.0 3.3 3 0 0 3 3 3 0 Kelch motif Fasciclin PF02469.17 EIE86325.1 - 1.3e-15 57.4 2.2 2.1e-11 43.9 0.1 3.0 2 1 0 2 2 2 2 Fasciclin domain COX5B PF01215.14 EIE86326.1 - 2.1e-37 127.8 0.0 2.4e-37 127.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-C4_Topoisom PF01396.14 EIE86326.1 - 0.0052 16.2 0.7 0.55 9.7 0.0 2.2 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger zf-CHCC PF10276.4 EIE86326.1 - 0.0068 16.2 0.3 0.011 15.5 0.2 1.3 1 0 0 1 1 1 1 Zinc-finger domain COG6 PF06419.6 EIE86326.1 - 0.14 10.3 0.0 0.17 9.9 0.0 1.1 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 NDUFA12 PF05071.11 EIE86327.1 - 1.6e-14 54.2 2.4 1.9e-14 53.9 1.7 1.0 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 zf-CCCH PF00642.19 EIE86328.1 - 6.1e-22 76.8 34.6 5.4e-05 22.7 0.9 6.1 6 0 0 6 6 6 6 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EIE86328.1 - 0.00019 21.3 55.9 0.011 15.7 1.4 7.9 7 2 0 7 7 7 5 Zinc finger C-x8-C-x5-C-x3-H type Acetyltransf_1 PF00583.19 EIE86330.1 - 2.2e-10 40.4 0.1 3.6e-10 39.7 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EIE86330.1 - 2.1e-08 34.2 0.0 3e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EIE86330.1 - 0.00026 21.0 0.0 0.00032 20.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.1 EIE86330.1 - 0.00032 21.2 0.1 0.0012 19.4 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EIE86330.1 - 0.011 15.4 0.1 0.022 14.4 0.1 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_9 PF13527.1 EIE86330.1 - 0.041 13.7 0.1 0.074 12.9 0.1 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EIE86330.1 - 0.14 11.9 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain p450 PF00067.17 EIE86331.1 - 6.3e-69 232.6 0.0 6.9e-69 232.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GHMP_kinases_N PF00288.21 EIE86332.1 - 1.3e-14 54.0 0.4 1.2e-13 50.8 0.1 2.6 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EIE86332.1 - 0.00076 19.6 0.0 0.0018 18.4 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal PspB PF06667.7 EIE86332.1 - 0.16 11.9 0.0 0.29 11.1 0.0 1.3 1 0 0 1 1 1 0 Phage shock protein B Pterin_bind PF00809.17 EIE86333.1 - 1.2e-66 224.1 0.0 2.4e-66 223.1 0.0 1.6 1 0 0 1 1 1 1 Pterin binding enzyme FolB PF02152.13 EIE86333.1 - 4.7e-45 152.3 1.8 1.8e-21 76.3 0.1 2.4 2 0 0 2 2 2 2 Dihydroneopterin aldolase HPPK PF01288.15 EIE86333.1 - 8.1e-42 141.9 0.0 1.7e-41 140.9 0.0 1.6 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) Suppressor_APC PF11414.3 EIE86333.1 - 0.12 12.1 0.0 0.47 10.2 0.0 2.1 1 0 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein Fe_hyd_lg_C PF02906.9 EIE86334.1 - 7.9e-85 284.5 0.1 1.6e-84 283.5 0.1 1.5 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Fe_hyd_SSU PF02256.12 EIE86334.1 - 1.9e-05 24.5 0.0 4.5e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Iron hydrogenase small subunit UQ_con PF00179.21 EIE86335.1 - 5.3e-14 51.8 0.1 5.8e-14 51.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EIE86335.1 - 0.0039 17.0 0.0 0.0041 17.0 0.0 1.2 1 0 0 1 1 1 1 RWD domain AA_permease PF00324.16 EIE86336.1 - 6.2e-91 305.1 28.9 7.3e-91 304.8 20.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EIE86336.1 - 1.7e-33 115.8 33.3 2.2e-33 115.4 23.1 1.0 1 0 0 1 1 1 1 Amino acid permease DUF3593 PF12159.3 EIE86336.1 - 0.035 13.8 0.0 0.035 13.8 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3593) AA_permease PF00324.16 EIE86337.1 - 1.7e-07 29.9 2.7 1.9e-07 29.8 1.9 1.0 1 0 0 1 1 1 1 Amino acid permease DUF2508 PF10704.4 EIE86339.1 - 0.14 12.3 2.6 3.1 8.0 0.5 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2508) RdRP PF05183.7 EIE86340.1 - 5.8e-140 467.7 0.0 7.8e-140 467.3 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase RRM_1 PF00076.17 EIE86340.1 - 6.1e-39 131.5 0.1 2.1e-17 62.4 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE86340.1 - 3.1e-18 65.5 0.0 1.3e-11 44.2 0.0 4.0 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE86340.1 - 2.5e-17 62.4 0.1 4.4e-10 39.2 0.0 3.7 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EIE86340.1 - 3.3e-05 23.5 1.4 7.2e-05 22.4 0.0 2.4 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 EIE86340.1 - 0.13 12.1 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 RNA binding motif Zn_clus PF00172.13 EIE86341.1 - 4.7e-08 32.8 12.0 1.2e-07 31.5 8.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acyl-CoA_dh_M PF02770.14 EIE86342.1 - 4.2e-10 38.9 0.8 9.2e-10 37.8 0.2 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.1 EIE86342.1 - 1.1e-07 32.1 0.0 2.4e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.19 EIE86342.1 - 6.2e-07 29.6 0.0 3.3e-06 27.2 0.0 2.2 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain ACOX PF01756.14 EIE86342.1 - 1.6e-05 24.3 0.1 3.6e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA oxidase MBOAT PF03062.14 EIE86343.1 - 1.3e-19 70.5 11.9 1.5e-19 70.2 8.3 1.0 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 EIE86343.1 - 0.084 12.9 7.4 0.04 13.9 2.9 2.1 2 0 0 2 2 2 0 Membrane bound O-acyl transferase family FH2 PF02181.18 EIE86344.1 - 7e-76 255.5 19.0 3.8e-75 253.0 5.8 2.5 2 0 0 2 2 2 2 Formin Homology 2 Domain Drf_FH3 PF06367.11 EIE86344.1 - 2.3e-39 134.8 3.4 2.3e-39 134.8 2.4 3.0 3 1 0 3 3 3 1 Diaphanous FH3 Domain Gluconate_2-dh3 PF13618.1 EIE86344.1 - 0.0041 17.2 2.0 0.23 11.5 0.0 3.5 3 0 0 3 3 3 1 Gluconate 2-dehydrogenase subunit 3 Chrome_Resist PF09828.4 EIE86344.1 - 0.015 15.4 2.2 0.52 10.5 0.0 2.6 2 0 0 2 2 2 0 Chromate resistance exported protein Prefoldin PF02996.12 EIE86345.1 - 1.8e-16 59.8 4.9 1.5e-14 53.6 3.4 2.1 1 1 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.1 EIE86345.1 - 4.3e-05 23.2 0.7 6.8e-05 22.5 0.5 1.3 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.15 EIE86345.1 - 0.0047 16.6 11.1 0.089 12.5 3.5 2.6 1 1 1 2 2 2 2 Prefoldin subunit Spc7 PF08317.6 EIE86345.1 - 0.0066 15.1 8.0 0.012 14.3 5.4 1.5 1 1 0 1 1 1 1 Spc7 kinetochore protein WEMBL PF05701.6 EIE86345.1 - 0.0067 14.9 6.0 0.0073 14.8 4.1 1.0 1 0 0 1 1 1 1 Weak chloroplast movement under blue light GAS PF13851.1 EIE86345.1 - 0.019 14.1 7.2 0.024 13.8 5.0 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Sec8_exocyst PF04048.9 EIE86345.1 - 0.027 14.1 3.1 0.32 10.6 0.2 2.2 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain DUF2164 PF09932.4 EIE86345.1 - 0.055 13.2 2.2 0.24 11.2 0.0 2.6 2 2 1 3 3 3 0 Uncharacterized conserved protein (DUF2164) DUF2115 PF09888.4 EIE86345.1 - 0.055 13.5 1.2 0.16 12.0 0.0 1.8 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) TMF_TATA_bd PF12325.3 EIE86345.1 - 0.057 13.1 6.4 0.097 12.4 0.7 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF3391 PF11871.3 EIE86345.1 - 0.1 12.8 0.9 0.5 10.5 0.1 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF3391) COG2 PF06148.6 EIE86345.1 - 0.12 12.2 5.2 0.99 9.2 0.1 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 FliJ PF02050.11 EIE86345.1 - 0.26 11.3 5.5 0.66 10.0 0.9 2.4 1 1 1 2 2 2 0 Flagellar FliJ protein ApoO PF09769.4 EIE86345.1 - 0.38 10.4 1.9 4.7 6.9 0.1 2.3 1 1 1 2 2 2 0 Apolipoprotein O SYCE1 PF15233.1 EIE86345.1 - 0.53 10.2 8.0 1 9.3 0.6 2.1 1 1 1 2 2 2 0 Synaptonemal complex central element protein 1 Mod_r PF07200.8 EIE86345.1 - 0.61 9.9 9.3 1.8 8.4 0.9 2.1 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Fib_alpha PF08702.5 EIE86345.1 - 2 8.5 9.3 2.1 8.4 1.7 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family IncA PF04156.9 EIE86345.1 - 2.4 7.7 7.9 8.1 5.9 5.4 1.8 1 1 0 1 1 1 0 IncA protein NPV_P10 PF05531.7 EIE86345.1 - 4 7.7 10.1 1.4e+03 -0.4 7.0 2.7 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Sec2p PF06428.6 EIE86345.1 - 4.5 7.1 10.6 3.6 7.5 0.9 2.5 1 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p COX4 PF02936.9 EIE86346.1 - 1.2e-35 122.2 0.1 1.4e-35 122.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF1138 PF06592.8 EIE86346.1 - 0.1 12.6 0.2 0.33 10.9 0.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1138) HLH PF00010.21 EIE86347.1 - 1.3e-16 60.0 1.6 2.5e-16 59.1 1.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF2423 PF10338.4 EIE86347.1 - 1.2 9.1 4.8 0.69 9.9 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2423) Mito_carr PF00153.22 EIE86348.1 - 4.5e-50 167.3 0.6 5.1e-24 83.8 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein DUF3158 PF11358.3 EIE86348.1 - 0.076 12.5 0.2 0.12 11.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3158) Utp14 PF04615.8 EIE86348.1 - 0.1 10.7 0.2 0.13 10.3 0.1 1.1 1 0 0 1 1 1 0 Utp14 protein Ras PF00071.17 EIE86349.1 - 1.3e-05 24.5 0.0 1.3e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIE86349.1 - 0.00089 19.7 0.0 0.0009 19.7 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein AAA_25 PF13481.1 EIE86349.1 - 0.0043 16.4 0.0 0.0043 16.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain CbiA PF01656.18 EIE86349.1 - 0.026 13.9 0.1 0.03 13.7 0.1 1.1 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_24 PF13479.1 EIE86349.1 - 0.1 12.1 0.1 0.1 12.1 0.0 1.1 1 0 0 1 1 1 0 AAA domain DUF1394 PF07159.7 EIE86350.1 - 1.5e-23 83.3 0.3 9.1e-22 77.5 0.2 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1394) Aldo_ket_red PF00248.16 EIE86351.1 - 2.4e-59 200.5 0.0 2.8e-59 200.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DSS1_SEM1 PF05160.8 EIE86352.1 - 3.5e-20 71.5 25.0 3.5e-20 71.5 17.4 1.4 1 1 0 1 1 1 1 DSS1/SEM1 family DUF2947 PF11163.3 EIE86352.1 - 0.017 14.7 5.6 0.017 14.6 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2947) Glyco_hydro_9 PF00759.14 EIE86353.1 - 7.7e-109 364.5 14.1 8.7e-109 364.3 9.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 VSP PF03302.8 EIE86353.1 - 0.12 11.0 0.5 0.18 10.3 0.3 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein Oxysterol_BP PF01237.13 EIE86354.1 - 4.1e-84 282.0 0.1 5.1e-84 281.7 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein zf-C2H2_2 PF12756.2 EIE86355.1 - 1.2e-35 121.6 15.3 4.7e-23 81.2 0.2 3.7 4 0 0 4 4 4 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 EIE86355.1 - 2.1e-05 24.4 0.7 2.1e-05 24.4 0.5 2.9 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EIE86355.1 - 0.00043 20.3 0.5 0.0014 18.7 0.4 2.0 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 EIE86355.1 - 0.0012 19.0 1.0 0.0012 19.0 0.7 5.2 5 0 0 5 5 5 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIE86355.1 - 0.019 15.2 0.5 0.019 15.2 0.4 4.6 4 0 0 4 4 4 0 C2H2-type zinc finger DUF2935 PF11155.3 EIE86355.1 - 0.028 14.5 1.5 0.076 13.1 1.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) Tis11B_N PF04553.7 EIE86355.1 - 0.095 12.8 1.2 1.4 9.1 1.0 2.5 3 0 0 3 3 3 0 Tis11B like protein, N terminus zf-BED PF02892.10 EIE86355.1 - 0.12 12.1 0.2 0.12 12.1 0.2 3.1 3 0 0 3 3 3 0 BED zinc finger NDK PF00334.14 EIE86357.1 - 2.6e-54 182.6 0.0 3.7e-54 182.1 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase HSP70 PF00012.15 EIE86358.1 - 4.3e-242 804.3 13.3 4.9e-242 804.1 9.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EIE86358.1 - 1.1e-17 63.6 2.8 1.1e-16 60.4 1.2 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 EIE86358.1 - 0.0011 18.6 0.0 0.0026 17.3 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 EIE86358.1 - 0.017 14.9 8.1 0.15 11.9 0.0 3.9 3 3 0 3 3 3 0 Cell division protein FtsA Asp_decarbox PF02261.11 EIE86358.1 - 0.023 14.2 0.1 0.086 12.4 0.0 2.0 2 0 0 2 2 2 0 Aspartate decarboxylase eIF3_N PF09440.5 EIE86358.1 - 0.1 12.7 4.8 0.076 13.1 1.9 1.8 2 0 0 2 2 2 0 eIF3 subunit 6 N terminal domain Homeobox PF00046.24 EIE86359.1 - 3.5e-16 58.5 0.9 7.2e-16 57.5 0.6 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EIE86359.1 - 0.026 14.2 0.0 0.058 13.1 0.0 1.6 1 0 0 1 1 1 0 Homeobox KN domain HTH_23 PF13384.1 EIE86359.1 - 0.037 13.7 0.0 0.075 12.7 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain Calcipressin PF04847.7 EIE86359.1 - 0.06 12.9 1.1 0.092 12.3 0.2 1.7 1 1 1 2 2 2 0 Calcipressin SH3_2 PF07653.12 EIE86360.1 - 9.8e-09 34.5 0.1 6.6e-08 31.9 0.0 2.2 3 0 0 3 3 3 1 Variant SH3 domain SH3_9 PF14604.1 EIE86360.1 - 1.9e-08 33.7 0.2 3.1e-08 33.0 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EIE86360.1 - 8.8e-07 28.2 0.0 1.4e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 SH3 domain DUF490 PF04357.8 EIE86360.1 - 0.007 15.5 0.0 0.0079 15.3 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF490) Pyrophosphatase PF00719.14 EIE86361.1 - 4.6e-54 182.1 0.8 5.9e-54 181.7 0.6 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase Ribosomal_S6e PF01092.14 EIE86362.1 - 5.2e-48 161.8 0.3 5.2e-48 161.8 0.2 2.0 2 0 0 2 2 2 1 Ribosomal protein S6e EF-1_beta_acid PF10587.4 EIE86362.1 - 9.9 6.4 9.4 23 5.2 6.6 1.6 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region BTB_2 PF02214.17 EIE86363.1 - 0.16 12.1 0.4 5.6 7.2 0.0 2.4 1 1 1 2 2 2 0 BTB/POZ domain Fibrillarin PF01269.12 EIE86364.1 - 1.7e-111 370.6 0.0 2.1e-111 370.3 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 EIE86364.1 - 3.9e-05 23.2 0.0 5.9e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.1 EIE86364.1 - 0.00033 20.2 0.0 0.00044 19.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EIE86364.1 - 0.017 14.6 0.0 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CM_2 PF01817.16 EIE86365.1 - 0.048 13.7 4.4 6.4 6.9 0.0 3.5 3 1 0 3 3 3 0 Chorismate mutase type II Sod_Cu PF00080.15 EIE86366.1 - 1.9e-46 157.7 2.2 2.3e-46 157.4 1.5 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Rhomboid PF01694.17 EIE86367.1 - 1.2e-33 116.2 14.5 1.2e-33 116.2 10.1 1.9 2 1 1 3 3 3 1 Rhomboid family DUF2177 PF09945.4 EIE86367.1 - 0.083 12.8 3.8 0.24 11.3 0.2 2.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2177) SE PF08491.5 EIE86370.1 - 1.5e-108 361.8 0.0 1.9e-108 361.5 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.14 EIE86370.1 - 1e-10 41.2 0.0 1.2e-05 24.5 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EIE86370.1 - 5.8e-06 25.4 0.1 2.2e-05 23.5 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 EIE86370.1 - 9.6e-05 21.5 0.1 0.00017 20.7 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 EIE86370.1 - 0.0021 18.0 0.6 0.0042 17.0 0.4 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EIE86370.1 - 0.0071 16.2 0.0 0.01 15.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EIE86370.1 - 0.008 15.3 0.8 0.012 14.7 0.5 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 EIE86370.1 - 0.008 15.0 0.0 0.01 14.7 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.22 EIE86370.1 - 0.0099 16.2 0.2 0.02 15.3 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EIE86370.1 - 0.018 13.9 0.9 0.025 13.4 0.6 1.1 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.13 EIE86370.1 - 0.08 12.5 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GDI PF00996.13 EIE86370.1 - 0.09 11.0 0.0 0.14 10.4 0.0 1.1 1 0 0 1 1 1 0 GDP dissociation inhibitor HI0933_like PF03486.9 EIE86370.1 - 0.094 11.1 0.0 0.13 10.6 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein Shikimate_DH PF01488.15 EIE86370.1 - 0.14 12.2 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase bZIP_1 PF00170.16 EIE86371.1 - 2.6e-11 43.2 8.6 2.6e-11 43.2 6.0 2.6 3 0 0 3 3 3 1 bZIP transcription factor bZIP_2 PF07716.10 EIE86371.1 - 5.8e-07 29.2 9.1 5.8e-07 29.2 6.3 3.0 3 0 0 3 3 3 1 Basic region leucine zipper Aft1_OSA PF11785.3 EIE86371.1 - 9.8e-06 26.0 2.3 9.8e-06 26.0 1.6 3.4 3 2 1 4 4 4 1 Aft1 osmotic stress response (OSM) domain Aft1_HRA PF11786.3 EIE86371.1 - 2.1e-05 24.6 0.0 5.3e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Aft1 HRA domain bZIP_Maf PF03131.12 EIE86371.1 - 0.019 15.2 4.0 0.019 15.2 2.8 2.9 1 1 1 2 2 1 0 bZIP Maf transcription factor HALZ PF02183.13 EIE86371.1 - 0.028 14.1 2.9 0.057 13.1 2.0 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper CDC45 PF02724.9 EIE86371.1 - 0.88 7.5 14.8 1.2 7.0 10.3 1.1 1 0 0 1 1 1 0 CDC45-like protein FAM60A PF15396.1 EIE86371.1 - 0.97 9.1 10.3 1.6 8.4 7.1 1.4 1 0 0 1 1 1 0 Protein Family FAM60A APG6 PF04111.7 EIE86371.1 - 1.5 7.7 16.5 2.3 7.2 11.4 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 LMBR1 PF04791.11 EIE86371.1 - 4.1 5.8 6.4 5.3 5.5 4.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DivIC PF04977.10 EIE86371.1 - 8.1 6.0 11.6 1.8 8.1 2.3 2.5 2 0 0 2 2 2 0 Septum formation initiator eRF1_3 PF03465.10 EIE86372.1 - 2.6e-19 69.5 0.2 8e-19 67.9 0.0 1.8 2 0 0 2 2 2 1 eRF1 domain 3 eRF1_2 PF03464.10 EIE86372.1 - 3.7e-18 66.1 0.5 6.6e-18 65.3 0.4 1.4 1 0 0 1 1 1 1 eRF1 domain 2 PDEase_II PF02112.10 EIE86372.1 - 0.0098 14.8 0.2 0.012 14.5 0.1 1.2 1 0 0 1 1 1 1 cAMP phosphodiesterases class-II DUF2765 PF10963.3 EIE86372.1 - 0.012 15.5 0.1 0.028 14.3 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2765) G-patch PF01585.18 EIE86373.1 - 1.5e-12 47.0 0.3 3.6e-12 45.8 0.2 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EIE86373.1 - 0.00061 19.5 7.0 0.00061 19.5 4.9 2.6 1 1 1 2 2 2 1 DExH-box splicing factor binding site EAP30 PF04157.11 EIE86373.1 - 0.1 11.7 0.1 0.1 11.7 0.1 2.2 2 0 0 2 2 2 0 EAP30/Vps36 family Glutaredoxin2_C PF04399.8 EIE86373.1 - 1.3 8.6 4.0 0.64 9.6 0.5 2.0 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain AATF-Che1 PF13339.1 EIE86373.1 - 4.3 7.4 11.5 1.2 9.2 0.5 2.7 3 0 0 3 3 3 0 Apoptosis antagonizing transcription factor Nop53 PF07767.6 EIE86374.1 - 3.1e-67 227.2 51.9 3.7e-67 226.9 36.0 1.0 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) Drc1-Sld2 PF11719.3 EIE86374.1 - 0.013 14.6 34.3 0.018 14.1 23.8 1.2 1 0 0 1 1 1 0 DNA replication and checkpoint protein CesA PF11439.3 EIE86374.1 - 0.19 11.6 10.9 3.7 7.5 0.4 2.8 2 0 0 2 2 2 0 Type III secretion system filament chaperone CesA CBM_21 PF03370.8 EIE86375.1 - 7.1e-27 93.6 7.3 1.6e-26 92.4 5.0 1.6 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit CBM_25 PF03423.8 EIE86375.1 - 0.0069 16.4 1.7 0.021 14.8 1.2 1.8 1 0 0 1 1 1 1 Carbohydrate binding domain (family 25) DUF1720 PF08226.6 EIE86376.1 - 2e-14 53.4 60.5 2.9e-09 36.8 10.9 2.9 2 1 0 2 2 2 2 Domain of unknown function (DUF1720) LysM PF01476.15 EIE86377.1 - 4.9e-08 32.7 0.1 1.1e-07 31.6 0.1 1.6 1 0 0 1 1 1 1 LysM domain SERTA PF06031.8 EIE86379.1 - 0.012 14.9 0.0 0.031 13.5 0.0 1.8 2 0 0 2 2 2 0 SERTA motif DUF4424 PF14415.1 EIE86379.1 - 0.07 12.6 0.1 0.081 12.4 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4424) adh_short PF00106.20 EIE86381.1 - 9.2e-24 84.2 0.1 1.1e-23 83.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIE86381.1 - 9.8e-12 45.1 0.1 1.4e-11 44.6 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIE86381.1 - 1.7e-10 40.8 0.1 2.3e-10 40.4 0.1 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EIE86381.1 - 6.1e-06 26.3 0.1 1.3e-05 25.3 0.1 1.4 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EIE86381.1 - 0.00011 21.6 0.2 0.00014 21.3 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 EIE86381.1 - 0.00079 18.6 0.2 0.019 14.1 0.1 2.5 1 1 1 2 2 2 1 Fungal family of unknown function (DUF1776) NmrA PF05368.8 EIE86381.1 - 0.0011 18.2 0.0 0.002 17.4 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family RTX_C PF08339.5 EIE86381.1 - 0.077 12.7 1.3 0.11 12.2 0.9 1.3 1 0 0 1 1 1 0 RTX C-terminal domain MULE PF10551.4 EIE86382.1 - 0.075 13.2 0.0 0.2 11.8 0.0 1.7 1 1 0 1 1 1 0 MULE transposase domain LysM PF01476.15 EIE86383.1 - 3.6e-08 33.1 0.1 8.3e-08 32.0 0.1 1.6 1 0 0 1 1 1 1 LysM domain z-alpha PF02295.12 EIE86383.1 - 0.35 10.6 7.0 36 4.2 0.1 3.7 3 0 0 3 3 3 0 Adenosine deaminase z-alpha domain Amidohydro_4 PF13147.1 EIE86384.1 - 2.1e-12 47.6 0.5 2e-06 28.0 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_1 PF01979.15 EIE86384.1 - 2.4e-10 40.5 0.1 3.7e-09 36.6 0.0 2.2 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_5 PF13594.1 EIE86384.1 - 2.5e-06 27.1 0.0 7.1e-06 25.7 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EIE86384.1 - 8.2e-06 25.2 0.0 1.7e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Amidohydrolase family PH PF00169.24 EIE86385.1 - 2.4e-09 37.3 5.0 1.4e-06 28.4 0.0 3.3 3 0 0 3 3 3 2 PH domain PH_9 PF15410.1 EIE86385.1 - 1.4e-05 25.2 0.5 0.00018 21.6 0.0 3.0 3 1 0 3 3 3 1 Pleckstrin homology domain MRP-S26 PF14943.1 EIE86385.1 - 0.085 12.4 6.2 0.1 12.1 0.4 2.5 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 DUF342 PF03961.8 EIE86386.1 - 0.29 9.4 6.8 0.076 11.4 0.8 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF342) DUF1900 PF08954.6 EIE86388.1 - 7.6e-74 245.6 0.0 6.1e-39 132.6 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF1900) WD40 PF00400.27 EIE86388.1 - 2.2e-10 40.0 19.9 0.0039 17.0 0.0 8.8 9 0 0 9 9 9 4 WD domain, G-beta repeat DUF1899 PF08953.6 EIE86388.1 - 1.9e-06 27.3 0.2 0.032 13.8 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF1899) Pkinase PF00069.20 EIE86388.1 - 2.2e-05 23.7 0.0 4e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 EIE86388.1 - 6e-05 22.2 0.0 9.5e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIE86388.1 - 0.00048 19.9 0.0 0.00089 19.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EIE86388.1 - 0.011 14.8 0.0 0.021 13.9 0.0 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase Choline_kinase PF01633.15 EIE86388.1 - 0.017 14.7 0.0 0.04 13.4 0.0 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase MHC_II_alpha PF00993.15 EIE86388.1 - 0.035 13.6 0.0 0.091 12.3 0.0 1.6 1 0 0 1 1 1 0 Class II histocompatibility antigen, alpha domain Pkinase_Tyr PF07714.12 EIE86388.1 - 0.039 13.0 0.0 0.074 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase CytochromB561_N PF09786.4 EIE86388.1 - 0.044 12.2 3.6 0.073 11.5 2.5 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal Spexin PF15171.1 EIE86388.1 - 0.077 12.9 0.1 0.2 11.6 0.1 1.7 1 0 0 1 1 1 0 Neuropeptide secretory protein family, NPQ, spexin WaaY PF06176.6 EIE86388.1 - 0.13 11.4 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Tubulin PF00091.20 EIE86389.1 - 8.1e-72 241.5 0.0 1.2e-71 240.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EIE86389.1 - 2e-47 160.3 0.4 4.3e-47 159.2 0.1 1.7 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EIE86389.1 - 9.1e-06 25.7 0.0 2.1e-05 24.5 0.0 1.6 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain THF_DHG_CYH PF00763.18 EIE86390.1 - 6.4e-20 71.3 0.1 1.4e-19 70.2 0.0 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 EIE86390.1 - 1.4e-14 53.5 0.1 5e-12 45.1 0.1 3.1 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain UDPG_MGDP_dh_N PF03721.9 EIE86390.1 - 0.033 13.5 0.6 1.9 7.8 0.1 2.8 2 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.14 EIE86390.1 - 0.039 13.0 0.0 0.068 12.3 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EIE86390.1 - 0.043 13.9 0.1 0.49 10.5 0.1 2.3 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF1368 PF07112.6 EIE86390.1 - 0.066 11.8 0.0 0.1 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1368) 4HBT PF03061.17 EIE86391.1 - 1.2e-11 44.5 0.9 9.4e-09 35.2 0.2 2.4 2 0 0 2 2 2 2 Thioesterase superfamily DUF2408 PF10303.4 EIE86392.1 - 1e-28 100.0 0.0 3.1e-21 75.8 0.0 2.5 2 1 0 2 2 2 2 Protein of unknown function (DUF2408) SecY PF00344.15 EIE86393.1 - 7.9e-26 90.7 7.5 2.2e-25 89.3 5.2 1.6 1 1 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 EIE86393.1 - 2.1e-10 39.8 0.0 5.1e-10 38.6 0.0 1.7 1 0 0 1 1 1 1 Plug domain of Sec61p DUF4525 PF15027.1 EIE86393.1 - 0.069 12.6 0.3 0.11 11.9 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4525) Polysacc_deac_1 PF01522.16 EIE86394.1 - 1.5e-25 89.2 0.0 2.5e-25 88.4 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase SH3_1 PF00018.23 EIE86396.1 - 7.9e-13 47.5 0.1 1.3e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EIE86396.1 - 1.7e-12 46.7 0.1 3.1e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EIE86396.1 - 4.5e-08 32.4 0.0 9.3e-08 31.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain EF-hand_4 PF12763.2 EIE86396.1 - 1.7e-05 24.4 0.5 0.0012 18.5 0.0 2.6 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand MMR_HSR1 PF01926.18 EIE86397.1 - 4.9e-18 65.1 0.3 1.2e-17 63.9 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EIE86397.1 - 1.4e-09 37.9 3.5 3.4e-07 30.2 0.2 2.8 2 1 1 3 3 3 2 Dynamin family DUF258 PF03193.11 EIE86397.1 - 9.7e-07 28.1 0.0 1.7e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 EIE86397.1 - 1.7e-06 27.4 0.0 2.7e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 EIE86397.1 - 2.4e-06 28.0 0.0 5.4e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein IIGP PF05049.8 EIE86397.1 - 6.4e-05 21.9 0.1 0.00011 21.1 0.0 1.4 1 1 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AIG1 PF04548.11 EIE86397.1 - 7.7e-05 21.8 0.4 0.00014 21.0 0.0 1.6 2 0 0 2 2 2 1 AIG1 family GBP PF02263.14 EIE86397.1 - 0.0013 17.8 0.0 0.002 17.2 0.0 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain MobB PF03205.9 EIE86397.1 - 0.014 15.1 0.1 0.027 14.1 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Arf PF00025.16 EIE86397.1 - 0.017 14.3 0.0 0.03 13.5 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family PduV-EutP PF10662.4 EIE86397.1 - 0.03 13.8 0.0 0.084 12.3 0.0 1.8 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.22 EIE86397.1 - 0.037 13.4 3.0 0.05 13.0 0.1 2.2 2 1 1 3 3 3 0 Elongation factor Tu GTP binding domain AAA_28 PF13521.1 EIE86397.1 - 0.045 13.7 0.2 0.075 12.9 0.1 1.5 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EIE86397.1 - 0.066 13.5 1.6 0.2 11.9 0.1 2.1 2 1 1 3 3 3 0 ABC transporter Septin PF00735.13 EIE86397.1 - 0.066 12.2 0.2 0.11 11.4 0.0 1.5 2 0 0 2 2 2 0 Septin AAA_17 PF13207.1 EIE86397.1 - 0.096 13.5 0.0 0.14 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain MULE PF10551.4 EIE86399.1 - 0.12 12.5 0.0 0.12 12.5 0.0 1.1 1 0 0 1 1 1 0 MULE transposase domain AA_permease_2 PF13520.1 EIE86402.1 - 5e-63 213.1 41.1 6e-63 212.8 28.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EIE86402.1 - 1e-23 83.4 35.9 1.3e-23 83.1 24.9 1.1 1 0 0 1 1 1 1 Amino acid permease E1-E2_ATPase PF00122.15 EIE86403.1 - 3e-28 98.4 3.4 4.2e-27 94.6 0.3 2.5 2 0 0 2 2 2 2 E1-E2 ATPase HAD PF12710.2 EIE86403.1 - 2.2e-18 67.1 0.1 4.8e-18 66.0 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EIE86403.1 - 3.4e-13 50.5 0.0 9.7e-13 49.0 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EIE86403.1 - 0.01 15.2 0.0 0.023 14.1 0.0 1.6 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus SCA7 PF08313.7 EIE86404.1 - 3.7e-08 32.8 0.2 8.8e-08 31.6 0.0 1.7 2 0 0 2 2 2 1 SCA7, zinc-binding domain YmgB PF10798.3 EIE86405.1 - 0.0088 15.8 0.1 0.63 9.9 0.0 2.3 2 1 0 2 2 2 2 Biofilm development protein YmgB/AriR priB_priC PF07445.7 EIE86405.1 - 0.024 14.0 0.1 0.027 13.9 0.1 1.1 1 0 0 1 1 1 0 Primosomal replication protein priB and priC Maf PF02545.9 EIE86405.1 - 0.064 12.3 0.0 0.072 12.1 0.0 1.2 1 0 0 1 1 1 0 Maf-like protein DUF3883 PF13020.1 EIE86407.1 - 0.056 13.1 0.1 1.1 9.0 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3883) DUF3877 PF12993.2 EIE86408.1 - 0.0047 16.5 1.9 0.47 9.9 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function, E. rectale Gene description (DUF3877) DDE_1 PF03184.14 EIE86409.1 - 4.9e-14 52.0 0.1 8.6e-11 41.3 0.1 2.4 1 1 1 2 2 2 2 DDE superfamily endonuclease Stork_head PF10264.4 EIE86409.1 - 0.03 14.4 0.0 0.14 12.3 0.0 2.1 1 1 1 2 2 2 0 Winged helix Storkhead-box1 domain DUF3126 PF11324.3 EIE86409.1 - 0.05 13.2 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3126) T_Ag_DNA_bind PF02217.11 EIE86409.1 - 0.11 12.9 0.1 0.27 11.6 0.1 1.6 1 0 0 1 1 1 0 Origin of replication binding protein DDE_3 PF13358.1 EIE86410.1 - 1.3e-05 25.0 0.0 1.8e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease ABC_tran PF00005.22 EIE86411.1 - 2.1e-36 125.2 0.0 3.6e-36 124.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EIE86411.1 - 1.5e-29 103.3 5.8 2.1e-29 102.8 4.0 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 EIE86411.1 - 2.5e-06 27.6 0.3 0.0037 17.2 0.0 2.6 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.1 EIE86411.1 - 7.7e-06 26.0 0.0 2.9e-05 24.1 0.0 2.0 2 1 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.1 EIE86411.1 - 9.8e-05 22.5 0.1 0.00092 19.3 0.1 2.2 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.14 EIE86411.1 - 0.00017 20.9 0.2 0.0047 16.1 0.1 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA PF00004.24 EIE86411.1 - 0.00046 20.3 0.0 0.0099 16.0 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EIE86411.1 - 0.0021 17.7 0.1 0.11 12.1 0.1 3.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EIE86411.1 - 0.0022 17.8 0.0 0.039 13.8 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EIE86411.1 - 0.0029 18.4 0.0 0.0065 17.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EIE86411.1 - 0.0036 16.7 0.1 0.014 14.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 EIE86411.1 - 0.0069 16.2 0.3 0.065 13.1 0.2 2.4 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 EIE86411.1 - 0.0093 15.4 0.1 0.024 14.1 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 EIE86411.1 - 0.012 14.7 0.0 0.022 13.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_28 PF13521.1 EIE86411.1 - 0.013 15.4 0.2 1.7 8.5 0.0 2.5 1 1 1 2 2 2 0 AAA domain ATP-synt_ab PF00006.20 EIE86411.1 - 0.046 13.2 0.0 0.074 12.5 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_33 PF13671.1 EIE86411.1 - 0.082 12.7 0.1 0.23 11.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EIE86411.1 - 0.1 12.9 0.0 0.27 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain UCR_TM PF02921.9 EIE86412.1 - 4.6e-20 71.6 2.3 8.8e-20 70.7 1.6 1.5 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.21 EIE86412.1 - 2e-18 65.7 0.1 3.5e-18 64.9 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain DUF1691 PF07950.6 EIE86413.1 - 4.8e-11 42.5 0.3 3.8e-05 23.5 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) SecY PF00344.15 EIE86414.1 - 3.9e-92 308.8 13.0 5.1e-92 308.4 9.0 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 EIE86414.1 - 5.7e-18 64.1 0.4 1.4e-17 62.8 0.3 1.7 1 0 0 1 1 1 1 Plug domain of Sec61p MAD PF05557.8 EIE86416.1 - 1.2e-11 43.4 1.8 1.2e-11 43.4 1.3 4.0 2 2 1 3 3 3 1 Mitotic checkpoint protein GST_C_3 PF14497.1 EIE86416.1 - 0.055 13.9 0.9 0.39 11.2 0.0 2.9 3 0 0 3 3 3 0 Glutathione S-transferase, C-terminal domain PCI PF01399.22 EIE86419.1 - 1.5e-12 47.7 0.1 5.2e-12 46.0 0.1 1.9 1 0 0 1 1 1 1 PCI domain DDE_3 PF13358.1 EIE86422.1 - 1.5e-08 34.5 0.0 2.2e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Apo-CIII PF05778.7 EIE86422.1 - 0.065 12.6 0.1 0.67 9.3 0.0 2.2 2 0 0 2 2 2 0 Apolipoprotein CIII (Apo-CIII) FAD_binding_3 PF01494.14 EIE86423.1 - 1.4e-18 67.1 0.1 1.2e-09 37.7 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Trp_halogenase PF04820.9 EIE86423.1 - 4.7e-05 22.2 0.1 0.059 11.9 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase DAO PF01266.19 EIE86423.1 - 0.00014 20.9 0.0 0.019 13.9 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.19 EIE86423.1 - 0.00023 20.3 0.0 0.15 11.1 0.0 2.8 4 0 0 4 4 4 2 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 EIE86423.1 - 0.0027 18.0 0.1 1.1 9.6 0.0 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIE86423.1 - 0.0036 17.2 0.0 0.0092 15.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EIE86423.1 - 0.026 13.4 0.0 0.3 9.9 0.0 2.1 1 1 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EIE86423.1 - 0.029 14.4 0.6 0.21 11.6 0.1 2.3 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EIE86423.1 - 0.067 13.0 0.0 0.17 11.7 0.0 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EIE86423.1 - 0.23 11.2 3.6 2 8.2 1.4 2.7 2 1 0 2 2 2 0 FAD-NAD(P)-binding GATA PF00320.22 EIE86424.1 - 2.7e-18 65.0 3.6 5.9e-18 63.9 2.5 1.6 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.5 EIE86424.1 - 2.1e-14 52.7 1.4 4.2e-14 51.8 1.0 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) TF_Zn_Ribbon PF08271.7 EIE86424.1 - 0.16 11.3 0.6 0.38 10.1 0.4 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding DZR PF12773.2 EIE86424.1 - 0.19 11.5 1.6 0.8 9.5 1.1 1.9 1 1 1 2 2 2 0 Double zinc ribbon Acetyltransf_1 PF00583.19 EIE86425.1 - 8.3e-13 48.1 0.0 1.1e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EIE86425.1 - 2.7e-11 43.4 0.0 4.4e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EIE86425.1 - 3.6e-08 33.4 0.0 4.4e-08 33.2 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EIE86425.1 - 6.6e-08 32.6 0.0 8.5e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EIE86425.1 - 0.0008 19.3 0.0 0.00097 19.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EIE86425.1 - 0.00082 19.2 0.1 0.0034 17.2 0.1 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EIE86425.1 - 0.0016 18.1 0.0 0.0028 17.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 EIE86425.1 - 0.11 12.4 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF3749 PF12568.3 EIE86425.1 - 0.15 11.6 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF4284 PF14112.1 EIE86426.1 - 0.061 13.8 0.0 0.073 13.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4284) WD40 PF00400.27 EIE86427.1 - 2.4e-16 58.8 5.9 4.1e-09 35.9 0.0 5.9 7 0 0 7 7 7 4 WD domain, G-beta repeat PQQ_2 PF13360.1 EIE86427.1 - 9.4e-06 25.2 0.0 2.5e-05 23.8 0.0 1.7 1 1 0 1 1 1 1 PQQ-like domain Beach PF02138.13 EIE86428.1 - 6.6e-62 209.3 0.1 1.4e-61 208.3 0.1 1.6 1 0 0 1 1 1 1 Beige/BEACH domain Pkinase PF00069.20 EIE86428.1 - 7.1e-11 41.7 0.0 7.7e-10 38.3 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Kinase-like PF14531.1 EIE86428.1 - 1.2e-05 24.4 0.0 2e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.12 EIE86428.1 - 0.0008 18.5 0.3 0.002 17.2 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 EIE86428.1 - 0.028 13.5 0.0 0.07 12.1 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CAF1-p150_C2 PF15539.1 EIE86428.1 - 0.03 13.4 0.0 0.058 12.5 0.0 1.4 1 0 0 1 1 1 0 CAF1 complex subunit p150, region binding to CAF1-p60 at C-term Cmc1 PF08583.5 EIE86429.1 - 6.5e-12 45.0 6.7 8.3e-12 44.7 4.6 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like ADAM_CR PF08516.7 EIE86429.1 - 0.08 12.9 1.0 0.093 12.7 0.7 1.1 1 0 0 1 1 1 0 ADAM cysteine-rich Pet191_N PF10203.4 EIE86429.1 - 0.64 10.1 5.0 0.67 10.0 1.3 2.0 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 TPT PF03151.11 EIE86430.1 - 1.6e-15 57.0 19.9 4.5e-15 55.6 3.5 2.3 2 1 0 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.6 EIE86430.1 - 8.5e-07 28.1 21.8 1.4e-06 27.4 15.1 1.3 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EIE86430.1 - 2.7e-05 24.2 9.2 2.7e-05 24.2 6.4 3.2 1 1 2 3 3 3 1 EamA-like transporter family Nuc_sug_transp PF04142.10 EIE86430.1 - 0.00046 19.3 4.5 0.00084 18.5 3.1 1.4 1 0 0 1 1 1 1 Nucleotide-sugar transporter DUF3311 PF11755.3 EIE86430.1 - 0.0022 17.4 8.0 0.0064 15.9 1.3 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3311) DUF3979 PF13141.1 EIE86430.1 - 0.084 12.7 0.1 1.4 8.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3979) Synaptobrevin PF00957.16 EIE86431.1 - 4.1e-15 55.1 0.7 6.5e-15 54.5 0.5 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 EIE86431.1 - 1.3e-07 31.0 0.0 2.8e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Regulated-SNARE-like domain Lipoprotein_X PF03305.8 EIE86431.1 - 0.026 13.9 1.0 0.035 13.4 0.7 1.1 1 0 0 1 1 1 0 Mycoplasma MG185/MG260 protein Terminase_2 PF03592.11 EIE86431.1 - 0.081 13.2 1.1 0.12 12.6 0.8 1.2 1 0 0 1 1 1 0 Terminase small subunit DUF16 PF01519.11 EIE86431.1 - 0.35 11.1 3.1 0.5 10.6 2.1 1.5 1 1 0 1 1 1 0 Protein of unknown function DUF16 SRP9-21 PF05486.7 EIE86431.1 - 0.79 9.5 3.2 2.1 8.1 2.2 1.8 1 1 0 1 1 1 0 Signal recognition particle 9 kDa protein (SRP9) PCI PF01399.22 EIE86432.1 - 1.9e-12 47.3 0.7 5.3e-12 45.9 0.2 2.0 2 0 0 2 2 2 1 PCI domain TPR_12 PF13424.1 EIE86432.1 - 0.022 14.6 0.4 0.65 9.9 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat S1_2 PF13509.1 EIE86432.1 - 0.026 14.4 0.0 0.11 12.4 0.0 1.9 2 0 0 2 2 2 0 S1 domain DUF845 PF05820.6 EIE86432.1 - 0.027 14.2 0.3 1.2 8.8 0.1 2.6 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF845) Apc3 PF12895.2 EIE86432.1 - 0.039 14.1 0.9 0.79 9.9 0.4 2.6 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 EIE86432.1 - 0.064 12.9 0.0 7.5 6.2 0.0 3.4 4 0 0 4 4 4 0 TPR repeat TPR_17 PF13431.1 EIE86432.1 - 0.076 13.2 0.0 1.8 8.9 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 EIE86432.1 - 0.083 12.7 6.2 2.2 8.2 0.2 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 EIE86432.1 - 0.38 10.7 6.4 0.53 10.3 0.2 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF4588 PF15251.1 EIE86433.1 - 2.6e-09 37.4 1.3 3.6e-09 36.9 0.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4588) Chalcone PF02431.10 EIE86433.1 - 0.065 12.6 0.0 0.11 11.8 0.0 1.5 1 1 0 1 1 1 0 Chalcone-flavanone isomerase PAC2 PF09754.4 EIE86433.1 - 0.067 13.0 0.0 0.089 12.6 0.0 1.2 1 0 0 1 1 1 0 PAC2 family DegT_DnrJ_EryC1 PF01041.12 EIE86433.1 - 0.16 10.9 0.3 0.27 10.2 0.2 1.5 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family AIM24 PF01987.12 EIE86435.1 - 3e-25 88.9 0.0 5.3e-25 88.1 0.0 1.4 1 1 0 1 1 1 1 Mitochondrial biogenesis AIM24 Ribosomal_L37ae PF01780.14 EIE86436.1 - 9.3e-41 137.6 10.8 1e-40 137.4 7.5 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.2 EIE86436.1 - 0.00069 19.3 2.2 0.001 18.8 1.5 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain A2L_zn_ribbon PF08792.5 EIE86436.1 - 0.0047 16.3 3.3 0.84 9.1 0.1 2.2 2 0 0 2 2 2 2 A2L zinc ribbon domain zf-FCS PF06467.9 EIE86436.1 - 0.027 14.0 2.2 0.75 9.4 0.1 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-H2C2_2 PF13465.1 EIE86436.1 - 0.08 13.2 1.4 2.5 8.5 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger double domain zf-BED PF02892.10 EIE86436.1 - 0.1 12.3 5.5 0.12 12.1 0.4 2.3 1 1 1 2 2 2 0 BED zinc finger Zn-ribbon_8 PF09723.5 EIE86436.1 - 0.17 11.8 1.7 0.9 9.5 0.1 2.2 2 0 0 2 2 2 0 Zinc ribbon domain Elf1 PF05129.8 EIE86436.1 - 0.27 10.9 2.7 0.5 10.0 1.9 1.5 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like zf-C2H2 PF00096.21 EIE86436.1 - 1.8 9.0 4.1 18 5.8 0.3 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF1154 PF06631.6 EIE86438.1 - 0.0071 15.9 4.8 0.3 10.7 0.6 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1154) Syntaxin-6_N PF09177.6 EIE86438.1 - 0.74 10.2 4.4 5.8 7.3 0.1 2.7 2 1 1 3 3 3 0 Syntaxin 6, N-terminal RhoGEF PF00621.15 EIE86439.1 - 7.6e-14 51.9 0.2 1.1e-13 51.5 0.1 1.2 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.24 EIE86440.1 - 0.00033 20.8 0.3 0.00045 20.3 0.2 1.2 1 0 0 1 1 1 1 PH domain Glyco_hydro_18 PF00704.23 EIE86441.1 - 1.8e-24 86.8 0.1 6.6e-24 84.9 0.1 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_19 PF03427.8 EIE86441.1 - 1.1e-13 50.6 13.3 3.3e-13 49.1 9.2 1.9 1 0 0 1 1 1 1 Carbohydrate binding domain (family 19) GTP_EFTU PF00009.22 EIE86442.1 - 6.6e-57 191.9 0.0 1.2e-56 191.1 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EIE86442.1 - 9.7e-37 125.1 0.0 2.4e-36 123.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EIE86442.1 - 5e-16 58.5 1.1 5e-16 58.5 0.7 2.4 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EIE86442.1 - 0.00097 19.0 0.3 0.0029 17.5 0.2 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 EIE86442.1 - 0.0013 18.3 0.4 0.0013 18.3 0.3 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 4 Semialdhyde_dhC PF02774.13 EIE86442.1 - 0.12 12.2 0.3 0.32 10.8 0.0 1.8 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain Pkinase PF00069.20 EIE86443.1 - 1.8e-48 164.9 0.3 2.1e-41 141.7 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIE86443.1 - 1.8e-17 63.2 0.0 4.1e-17 62.1 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE86443.1 - 3.3e-07 29.5 0.0 4.2e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EIE86443.1 - 4.3e-06 25.9 0.0 6.5e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIE86443.1 - 0.00012 21.9 0.0 0.00021 21.1 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EIE86443.1 - 0.004 16.7 0.2 0.0053 16.3 0.2 1.3 1 1 0 1 1 1 1 Choline/ethanolamine kinase Y_phosphatase PF00102.22 EIE86444.1 - 2.2e-67 226.8 0.8 2.7e-67 226.5 0.0 1.5 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EIE86444.1 - 0.0011 19.0 0.1 0.0027 17.7 0.1 1.8 1 1 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 EIE86444.1 - 0.0015 18.8 0.0 0.0028 17.9 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.15 EIE86444.1 - 0.0031 17.0 0.0 0.0054 16.3 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PET PF06297.9 EIE86444.1 - 0.024 14.2 0.0 0.059 13.0 0.0 1.7 1 0 0 1 1 1 0 PET Domain Arf PF00025.16 EIE86445.1 - 5.7e-80 266.6 0.1 6.5e-80 266.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EIE86445.1 - 2.8e-13 49.4 0.0 3.5e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EIE86445.1 - 5.7e-13 48.5 0.0 6.6e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EIE86445.1 - 2.1e-12 46.4 1.7 2.1e-09 36.5 0.2 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EIE86445.1 - 5e-11 42.1 0.0 5.9e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EIE86445.1 - 4.9e-09 36.7 0.0 6.8e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EIE86445.1 - 7.1e-06 25.9 0.0 1e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 EIE86445.1 - 0.0054 15.8 0.3 0.0094 15.0 0.2 1.6 1 1 0 1 1 1 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 EIE86445.1 - 0.041 13.3 0.1 0.36 10.2 0.0 1.9 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 EIE86445.1 - 0.074 12.9 0.1 0.13 12.1 0.1 1.7 1 1 0 1 1 1 0 AAA domain TPR_2 PF07719.12 EIE86446.1 - 3.6e-24 82.6 7.3 0.00046 19.8 0.0 8.5 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_11 PF13414.1 EIE86446.1 - 3.2e-21 74.7 7.6 4.4e-06 26.2 0.1 5.9 4 2 0 5 5 5 4 TPR repeat TPR_1 PF00515.23 EIE86446.1 - 3.5e-19 67.5 6.2 0.0015 18.0 0.0 8.5 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.1 EIE86446.1 - 3e-17 61.0 8.8 0.059 13.1 0.2 8.7 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_14 PF13428.1 EIE86446.1 - 3.3e-14 52.1 9.7 0.086 13.5 0.0 7.1 3 2 4 7 7 7 5 Tetratricopeptide repeat TPR_19 PF14559.1 EIE86446.1 - 1.3e-13 51.0 14.0 0.00054 20.2 0.2 6.7 5 2 2 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.1 EIE86446.1 - 7.1e-12 45.0 14.5 0.00022 21.1 0.2 5.4 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.1 EIE86446.1 - 1.6e-11 43.4 2.1 2 8.8 0.0 6.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 EIE86446.1 - 5e-11 42.9 7.2 0.028 15.1 0.0 6.2 4 2 1 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.1 EIE86446.1 - 5.7e-09 35.1 1.3 0.14 12.0 0.1 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 EIE86446.1 - 1.1e-07 31.8 14.2 0.00065 19.7 0.4 5.3 3 1 3 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EIE86446.1 - 0.00011 22.3 8.5 2 9.0 0.1 6.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_10 PF13374.1 EIE86446.1 - 0.00012 21.9 4.6 0.46 10.4 0.2 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_21 PF09976.4 EIE86446.1 - 0.00034 20.5 5.7 0.017 15.0 1.1 4.0 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 EIE86446.1 - 0.45 10.3 6.3 11 5.9 0.0 4.8 4 3 1 5 5 5 0 Tetratricopeptide repeat PhoD PF09423.5 EIE86447.1 - 1.5e-07 30.4 1.5 0.0003 19.4 0.0 2.9 2 1 1 3 3 3 2 PhoD-like phosphatase Sybindin PF04099.7 EIE86448.1 - 5.6e-24 84.4 2.6 2.7e-23 82.2 1.1 2.3 2 1 0 2 2 2 1 Sybindin-like family MutS_V PF00488.16 EIE86449.1 - 3.8e-65 219.5 0.0 1.2e-64 217.9 0.0 1.9 1 1 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EIE86449.1 - 3.3e-41 141.3 0.1 6.3e-41 140.4 0.0 1.5 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EIE86449.1 - 2e-34 117.9 0.2 3.7e-34 117.1 0.1 1.5 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 EIE86449.1 - 3.8e-11 43.1 0.0 1.4e-10 41.4 0.0 2.0 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 EIE86449.1 - 6.6e-11 42.2 0.0 2.4e-10 40.4 0.0 2.1 1 0 0 1 1 1 1 MutS family domain IV SRP54_N PF02881.14 EIE86449.1 - 0.029 14.4 0.0 0.25 11.4 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, helical bundle domain AAA_16 PF13191.1 EIE86449.1 - 0.04 13.8 1.0 0.73 9.7 0.0 3.0 3 0 0 3 3 3 0 AAA ATPase domain Tubulin PF00091.20 EIE86451.1 - 2.9e-73 246.2 0.0 4.7e-73 245.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EIE86451.1 - 2.2e-48 163.4 0.0 3.9e-48 162.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EIE86451.1 - 1.8e-05 24.7 0.0 4.8e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain O-FucT PF10250.4 EIE86452.1 - 0.0017 17.5 0.3 0.024 13.7 0.2 2.6 2 1 0 2 2 2 1 GDP-fucose protein O-fucosyltransferase RPN7 PF10602.4 EIE86453.1 - 0.0043 16.4 0.6 0.0073 15.7 0.4 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PIN_3 PF13470.1 EIE86453.1 - 0.012 16.3 1.1 0.029 15.0 0.7 1.7 1 1 0 1 1 1 0 PIN domain HlyD PF00529.15 EIE86453.1 - 0.17 11.1 2.9 0.38 10.0 0.1 2.0 2 0 0 2 2 2 0 HlyD family secretion protein TPR_14 PF13428.1 EIE86453.1 - 0.22 12.2 2.7 2.1 9.2 0.4 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Chitin_synth_2 PF03142.10 EIE86454.1 - 3.1e-231 768.3 0.4 4.3e-231 767.9 0.3 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 EIE86454.1 - 3.9e-93 312.7 0.2 4.2e-70 236.6 0.0 2.1 1 1 1 2 2 2 2 Myosin head (motor domain) Glyco_tranf_2_3 PF13641.1 EIE86454.1 - 9.1e-17 61.6 0.0 3.9e-14 52.9 0.0 2.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 EIE86454.1 - 8.2e-16 57.5 0.2 2.1e-11 43.4 0.1 2.8 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.6 EIE86454.1 - 1.1e-14 53.8 0.4 2.9e-14 52.5 0.3 1.8 1 0 0 1 1 1 1 DEK C terminal domain Glyco_trans_2_3 PF13632.1 EIE86454.1 - 4.3e-12 46.1 4.6 4.3e-12 46.1 3.2 2.8 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 EIE86454.1 - 0.0013 18.4 0.0 0.025 14.2 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EIE86454.1 - 0.0064 15.7 0.1 0.22 10.7 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 21 FA_desaturase PF00487.19 EIE86454.1 - 8.1 5.8 10.1 4.9 6.5 0.1 2.6 2 0 0 2 2 2 0 Fatty acid desaturase eIF-5_eIF-2B PF01873.12 EIE86456.1 - 2.2e-44 150.1 0.4 4.5e-44 149.1 0.1 1.6 2 0 0 2 2 2 1 Domain found in IF2B/IF5 W2 PF02020.13 EIE86456.1 - 2e-27 94.9 1.0 2e-27 94.9 0.7 2.5 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Yip1 PF04893.12 EIE86457.1 - 0.039 13.4 0.0 0.07 12.6 0.0 1.3 1 0 0 1 1 1 0 Yip1 domain Podoplanin PF05808.6 EIE86457.1 - 0.043 13.3 0.0 0.091 12.3 0.0 1.5 1 0 0 1 1 1 0 Podoplanin Mitofilin PF09731.4 EIE86457.1 - 2.7 6.5 8.3 3.5 6.1 5.8 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein GATase_2 PF00310.16 EIE86458.1 - 0.017 13.8 0.0 0.02 13.5 0.0 1.0 1 0 0 1 1 1 0 Glutamine amidotransferases class-II DUF1857 PF08982.6 EIE86458.1 - 0.064 12.8 0.0 0.082 12.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1857) NUDIX PF00293.23 EIE86459.1 - 7.2e-12 45.1 0.0 1.1e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Asn_synthase PF00733.16 EIE86460.1 - 1.4e-32 113.1 0.0 1.9e-32 112.8 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EIE86460.1 - 1.1e-09 38.0 0.0 7e-09 35.4 0.0 2.3 2 1 0 2 2 2 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EIE86460.1 - 1.5e-06 28.2 0.0 3.6e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain FAD-oxidase_C PF02913.14 EIE86461.1 - 5.2e-53 179.9 0.0 7e-53 179.4 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EIE86461.1 - 2.2e-30 104.9 0.2 3.3e-30 104.3 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pmp3 PF01679.12 EIE86462.1 - 0.00014 21.4 1.0 0.00014 21.4 0.7 2.1 3 0 0 3 3 3 1 Proteolipid membrane potential modulator Sigma70_ner PF04546.8 EIE86462.1 - 0.0013 18.3 7.7 0.0018 17.9 4.5 1.8 2 0 0 2 2 2 1 Sigma-70, non-essential region RXT2_N PF08595.6 EIE86462.1 - 0.014 15.1 6.0 0.03 14.1 4.2 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal TRAP_alpha PF03896.11 EIE86462.1 - 0.041 12.8 4.6 0.076 12.0 3.2 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF1201 PF06716.6 EIE86462.1 - 1.5 8.7 5.6 12 5.7 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1201) Cwf_Cwc_15 PF04889.7 EIE86462.1 - 3.1 7.4 18.3 7.2 6.2 12.7 1.6 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.7 EIE86462.1 - 3.3 5.4 19.3 4.9 4.9 13.4 1.1 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.7 EIE86462.1 - 4.5 6.4 11.9 6.9 5.8 8.2 1.2 1 0 0 1 1 1 0 NOA36 protein Nuc_H_symport PF03825.11 EIE86463.1 - 1.7e-05 23.7 2.0 0.0019 17.0 0.0 2.4 2 1 1 3 3 3 2 Nucleoside H+ symporter MFS_1 PF07690.11 EIE86463.1 - 2.6e-05 23.1 4.5 0.06 12.0 3.3 3.0 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF441 PF04284.8 EIE86463.1 - 0.046 13.6 4.7 0.071 12.9 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF441) OATP PF03137.15 EIE86463.1 - 0.05 11.6 0.0 0.055 11.5 0.0 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DNA_pol_B_thumb PF14791.1 EIE86463.1 - 0.13 11.9 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase beta thumb WD40 PF00400.27 EIE86464.1 - 9e-35 117.3 5.9 7.8e-12 44.6 0.4 4.6 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 EIE86464.1 - 1.7e-06 26.4 0.1 0.009 14.1 0.0 3.1 1 1 2 3 3 3 3 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 EIE86464.1 - 0.0023 17.6 0.0 0.011 15.5 0.0 2.1 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region CDtoxinA PF03498.9 EIE86464.1 - 0.038 13.3 0.0 0.8 9.0 0.0 2.4 2 0 0 2 2 2 0 Cytolethal distending toxin A/C family US22 PF02393.11 EIE86464.1 - 0.1 12.6 0.0 3.6 7.6 0.0 2.3 2 0 0 2 2 2 0 US22 like ORC2 PF04084.9 EIE86465.1 - 1.7e-58 198.0 0.0 3.4e-58 197.0 0.0 1.4 1 0 0 1 1 1 1 Origin recognition complex subunit 2 FYRC PF05965.9 EIE86465.1 - 0.05 13.4 0.3 0.38 10.5 0.0 2.4 2 0 0 2 2 2 0 F/Y rich C-terminus RhoGAP PF00620.22 EIE86466.1 - 2e-30 105.4 0.5 1.4e-22 79.8 0.1 2.7 1 1 1 2 2 2 2 RhoGAP domain Hairy_orange PF07527.8 EIE86466.1 - 0.09 12.5 0.1 0.22 11.2 0.0 1.7 1 0 0 1 1 1 0 Hairy Orange PC-Esterase PF13839.1 EIE86467.1 - 0.066 13.0 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Zwint PF15556.1 EIE86470.1 - 0.024 13.9 0.0 0.028 13.6 0.0 1.0 1 0 0 1 1 1 0 ZW10 interactor RVT_1 PF00078.22 EIE86474.1 - 1.1e-23 83.6 0.0 1.4e-23 83.3 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) BolA PF01722.13 EIE86476.1 - 2.1e-17 62.8 4.7 1.5e-15 56.8 3.2 2.2 1 1 0 1 1 1 1 BolA-like protein Vesiculo_matrix PF06326.7 EIE86476.1 - 0.048 13.1 1.2 0.19 11.1 1.0 1.8 1 1 1 2 2 2 0 Vesiculovirus matrix protein Ammonium_transp PF00909.16 EIE86477.1 - 6.2e-111 370.6 28.1 7.4e-111 370.4 19.5 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family PIP5K PF01504.13 EIE86478.1 - 1.9e-83 279.4 2.6 2.9e-83 278.8 1.8 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Glyco_hydro_3 PF00933.16 EIE86479.1 - 3.5e-69 233.0 0.0 4.7e-69 232.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Acetyltransf_7 PF13508.1 EIE86479.1 - 4.8e-18 65.0 0.6 6.2e-08 32.6 0.1 2.7 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EIE86479.1 - 6.2e-18 64.6 2.1 9.7e-11 41.5 0.0 3.5 3 0 0 3 3 3 2 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EIE86479.1 - 1.2e-14 54.4 1.3 3.7e-11 43.1 0.0 3.1 4 0 0 4 4 4 2 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EIE86479.1 - 1.6e-10 40.9 1.0 0.00062 19.6 0.0 3.5 2 2 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.5 EIE86479.1 - 1.5e-05 24.6 0.5 0.08 12.6 0.1 3.2 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_6 PF13480.1 EIE86479.1 - 2.6e-05 24.1 1.2 0.0002 21.3 0.1 2.7 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EIE86479.1 - 7.8e-05 22.4 0.2 0.024 14.5 0.0 2.6 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.1 EIE86479.1 - 0.0097 16.0 0.1 0.074 13.2 0.0 2.5 3 1 0 3 3 3 1 Acetyltransferase (GNAT) domain DUF2156 PF09924.4 EIE86479.1 - 0.018 13.8 0.1 0.2 10.4 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2156) MOZ_SAS PF01853.13 EIE86479.1 - 0.095 11.9 0.0 0.24 10.5 0.0 1.6 1 0 0 1 1 1 0 MOZ/SAS family VRR_NUC PF08774.6 EIE86480.1 - 0.0043 17.0 0.0 0.0065 16.4 0.0 1.3 1 0 0 1 1 1 1 VRR-NUC domain DUF4263 PF14082.1 EIE86480.1 - 0.017 15.0 0.3 0.093 12.6 0.0 2.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4263) Spt20 PF12090.3 EIE86480.1 - 0.063 12.6 0.2 0.074 12.3 0.1 1.1 1 0 0 1 1 1 0 Spt20 family HSDR_N_2 PF13588.1 EIE86480.1 - 0.066 13.0 0.2 0.13 12.0 0.1 1.5 1 1 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) DDE_1 PF03184.14 EIE86481.1 - 1e-14 54.1 0.9 2.3e-14 53.0 0.6 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EIE86481.1 - 0.032 13.9 0.1 0.056 13.1 0.1 1.6 1 1 0 1 1 1 0 DDE superfamily endonuclease CUE PF02845.11 EIE86482.1 - 0.021 14.3 1.7 0.058 12.8 0.0 2.3 3 0 0 3 3 3 0 CUE domain AMIN PF11741.3 EIE86482.1 - 0.076 12.9 0.6 0.1 12.5 0.4 1.3 1 0 0 1 1 1 0 AMIN domain Sec2p PF06428.6 EIE86483.1 - 7.5e-15 54.6 14.7 7.5e-15 54.6 10.2 2.6 1 1 1 2 2 2 1 GDP/GTP exchange factor Sec2p NPV_P10 PF05531.7 EIE86483.1 - 0.018 15.3 4.2 7.2 6.9 0.0 3.1 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF3584 PF12128.3 EIE86483.1 - 0.07 10.4 21.4 0.11 9.8 14.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Endonuc-BglII PF09195.6 EIE86483.1 - 0.081 12.3 4.6 18 4.7 3.2 3.0 1 1 0 1 1 1 0 Restriction endonuclease BglII TAF8_C PF10406.4 EIE86483.1 - 0.11 12.5 0.3 0.71 9.9 0.2 2.5 1 0 0 1 1 1 0 Transcription factor TFIID complex subunit 8 C-term Rootletin PF15035.1 EIE86483.1 - 0.25 11.2 28.0 0.4 10.6 4.2 2.7 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Virulence_fact PF13769.1 EIE86483.1 - 0.44 10.4 3.9 1.4 8.8 2.3 2.2 2 0 0 2 2 2 0 Virulence factor ALIX_LYPXL_bnd PF13949.1 EIE86483.1 - 0.53 9.1 26.6 0.18 10.7 14.4 2.1 2 0 0 2 2 2 0 ALIX V-shaped domain binding to HIV NADH-G_4Fe-4S_3 PF10588.4 EIE86483.1 - 1 8.6 6.4 0.24 10.6 0.2 2.7 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Val_tRNA-synt_C PF10458.4 EIE86483.1 - 1.7 8.7 22.0 5.8 7.0 0.7 5.2 5 2 0 5 5 5 0 Valyl tRNA synthetase tRNA binding arm LMBR1 PF04791.11 EIE86483.1 - 2.7 6.4 5.7 4.3 5.8 3.9 1.5 1 0 0 1 1 1 0 LMBR1-like membrane protein HAUS5 PF14817.1 EIE86483.1 - 8 4.8 23.1 1.8 7.0 13.7 1.6 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 5 Helicase_C PF00271.26 EIE86484.1 - 3.2e-21 74.9 0.0 2.9e-11 43.0 0.0 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.24 EIE86484.1 - 4.3e-14 52.3 0.1 7.6e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Glyco_transf_20 PF00982.16 EIE86485.1 - 8.6e-164 545.4 0.0 1.3e-163 544.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EIE86485.1 - 2.8e-78 262.0 0.0 5.1e-78 261.2 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase HAD PF12710.2 EIE86485.1 - 0.15 12.2 0.4 1.2 9.2 0.3 2.3 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase DDE_3 PF13358.1 EIE86488.1 - 2e-11 43.8 0.0 4.1e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 EIE86488.1 - 1.8e-09 37.7 0.0 4.6e-09 36.4 0.0 1.7 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.1 EIE86488.1 - 3.1e-08 33.4 0.0 2e-07 30.8 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.1 EIE86488.1 - 3.2e-07 29.7 0.1 1.4e-05 24.5 0.0 2.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.1 EIE86488.1 - 1.4e-05 25.7 0.0 6.1e-05 23.7 0.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_1 PF01527.15 EIE86488.1 - 4e-05 23.4 0.8 0.00014 21.7 0.0 2.2 3 0 0 3 3 3 1 Transposase HTH_17 PF12728.2 EIE86488.1 - 8.2e-05 22.7 0.0 0.0066 16.6 0.0 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.1 EIE86488.1 - 0.022 15.0 0.0 0.05 13.9 0.0 1.5 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 HTH_38 PF13936.1 EIE86488.1 - 0.025 14.1 0.0 0.22 11.0 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_30 PF13556.1 EIE86488.1 - 0.04 13.5 0.1 0.18 11.4 0.0 2.1 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain NAD_binding_4 PF07993.7 EIE86489.1 - 1.4e-42 145.3 0.0 5e-41 140.2 0.0 2.9 3 0 0 3 3 3 1 Male sterility protein AMP-binding PF00501.23 EIE86489.1 - 1.3e-41 142.4 0.0 3.6e-41 140.9 0.0 1.8 2 1 0 2 2 2 1 AMP-binding enzyme PP-binding PF00550.20 EIE86489.1 - 5.1e-08 33.0 0.0 2.1e-07 31.1 0.0 2.0 2 0 0 2 2 2 1 Phosphopantetheine attachment site Epimerase PF01370.16 EIE86489.1 - 0.00064 19.2 0.0 0.0053 16.2 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EIE86489.1 - 0.02 14.8 0.0 0.047 13.5 0.0 1.7 1 0 0 1 1 1 0 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EIE86489.1 - 0.057 12.3 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Syntaxin-18_N PF10496.4 EIE86490.1 - 1.5e-15 56.7 3.6 1.5e-15 56.7 2.5 3.1 3 1 1 4 4 4 1 SNARE-complex protein Syntaxin-18 N-terminus LMBR1 PF04791.11 EIE86490.1 - 0.92 8.0 3.8 0.88 8.0 2.0 1.4 1 1 0 1 1 1 0 LMBR1-like membrane protein DUF3918 PF13056.1 EIE86491.1 - 0.097 12.0 0.1 0.17 11.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3918) TCTP PF00838.12 EIE86492.1 - 2.8e-72 242.0 1.4 3.1e-72 241.9 1.0 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein GerPC PF10737.4 EIE86492.1 - 0.016 15.0 0.3 0.031 14.0 0.2 1.4 1 1 0 1 1 1 0 Spore germination protein GerPC Mus7 PF09462.5 EIE86492.1 - 0.067 12.0 0.0 0.08 11.7 0.0 1.1 1 0 0 1 1 1 0 Mus7/MMS22 family EMP70 PF02990.11 EIE86493.1 - 5.2e-204 678.5 8.0 7.1e-204 678.0 5.6 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 MCM PF00493.18 EIE86494.1 - 8.3e-129 429.1 0.8 8.3e-129 429.1 0.5 1.8 2 0 0 2 2 2 1 MCM2/3/5 family MCM_N PF14551.1 EIE86494.1 - 1.2e-23 83.8 2.0 1.5e-23 83.5 0.0 2.2 2 1 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EIE86494.1 - 3.2e-08 32.9 0.1 1.7e-06 27.3 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EIE86494.1 - 0.0012 18.4 0.0 0.0054 16.3 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EIE86494.1 - 0.005 16.3 0.0 0.014 14.8 0.0 1.7 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.9 EIE86494.1 - 0.031 14.0 0.0 0.23 11.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) PDCD2_C PF04194.8 EIE86494.1 - 1.1 8.8 6.8 75 2.8 4.2 3.0 3 0 0 3 3 3 0 Programmed cell death protein 2, C-terminal putative domain PYC_OADA PF02436.13 EIE86494.1 - 1.7 8.0 5.0 1.4 8.2 2.0 1.8 1 1 1 2 2 2 0 Conserved carboxylase domain HMG_box PF00505.14 EIE86495.1 - 5.9e-21 74.5 13.7 1.2e-13 51.1 2.9 2.5 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.5 EIE86495.1 - 1.9e-14 53.7 13.6 1.2e-08 35.1 3.6 2.4 2 0 0 2 2 2 2 HMG-box domain Peptidase_S49 PF01343.13 EIE86495.1 - 0.041 13.6 0.5 0.11 12.2 0.2 1.7 2 0 0 2 2 2 0 Peptidase family S49 PDZ_1 PF12812.2 EIE86496.1 - 1.2e-34 118.0 0.0 3.3e-24 84.5 0.0 2.8 2 0 0 2 2 2 2 PDZ-like domain PDZ_2 PF13180.1 EIE86496.1 - 7.1e-18 64.2 0.7 8.6e-06 25.5 0.0 5.8 5 1 0 5 5 5 4 PDZ domain Trypsin_2 PF13365.1 EIE86496.1 - 5.4e-11 42.5 0.1 2.8e-10 40.2 0.0 2.3 3 0 0 3 3 3 1 Trypsin-like peptidase domain PDZ PF00595.19 EIE86496.1 - 7.4e-11 42.0 0.0 0.012 15.7 0.0 4.6 4 0 0 4 4 4 3 PDZ domain (Also known as DHR or GLGF) Tricorn_PDZ PF14685.1 EIE86496.1 - 0.025 14.3 1.7 1.8 8.4 0.0 4.0 5 0 0 5 5 5 0 Tricorn protease PDZ domain Homeobox PF00046.24 EIE86497.1 - 0.00011 21.6 3.1 0.00011 21.6 2.1 2.1 2 0 0 2 2 2 1 Homeobox domain DUF1635 PF07795.6 EIE86497.1 - 0.012 14.9 1.7 0.014 14.7 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) UPF0560 PF10577.4 EIE86497.1 - 0.027 12.7 1.5 0.027 12.7 1.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 SR-25 PF10500.4 EIE86497.1 - 0.13 11.6 6.6 0.021 14.2 2.1 1.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein BAF1_ABF1 PF04684.8 EIE86497.1 - 0.36 9.6 1.9 0.38 9.5 1.3 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor F-112 PF09645.5 EIE86497.1 - 0.43 10.4 5.8 0.85 9.5 3.6 1.7 2 0 0 2 2 2 0 F-112 protein HAMP PF00672.20 EIE86498.1 - 9.1e-194 628.0 90.2 4.1e-09 36.5 0.1 25.2 24 0 0 24 24 24 23 HAMP domain HATPase_c PF02518.21 EIE86498.1 - 4.7e-29 100.3 0.3 2.9e-28 97.8 0.2 2.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EIE86498.1 - 6.6e-28 96.9 0.9 7.2e-25 87.1 0.1 2.9 2 0 0 2 2 2 2 Response regulator receiver domain HisKA PF00512.20 EIE86498.1 - 9.6e-18 63.9 2.8 1.1e-16 60.5 0.3 4.6 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain HTH_6 PF01418.12 EIE86498.1 - 2.3e-13 49.6 5.6 24 4.7 0.0 16.0 18 0 0 18 18 18 0 Helix-turn-helix domain, rpiR family DUF3199 PF11436.3 EIE86498.1 - 0.00077 19.3 4.2 1.9e+02 1.8 0.0 7.9 9 0 0 9 9 9 0 Protein of unknown function (DUF3199) HMG_box PF00505.14 EIE86498.1 - 0.0042 17.3 0.0 57 4.0 0.0 6.0 7 0 0 7 7 7 0 HMG (high mobility group) box DCR PF14047.1 EIE86498.1 - 0.38 11.0 1.2 11 6.3 0.3 3.9 2 1 0 2 2 2 0 Dppa2/4 conserved region SpoIIID PF12116.3 EIE86498.1 - 0.9 9.5 46.4 18 5.3 0.0 16.3 20 0 0 20 20 20 0 Stage III sporulation protein D Rubredoxin PF00301.15 EIE86498.1 - 2.5 8.0 0.1 7.6 6.5 0.1 1.8 1 0 0 1 1 1 0 Rubredoxin EF-hand_4 PF12763.2 EIE86499.1 - 5e-22 77.6 0.0 5.1e-21 74.3 0.0 2.5 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand Dynamin_N PF00350.18 EIE86499.1 - 1.3e-20 73.9 0.0 7.7e-20 71.3 0.0 2.2 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 EIE86499.1 - 2.2e-09 37.3 0.1 8.3e-09 35.4 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EIE86499.1 - 1.9e-06 27.4 0.0 8.3e-06 25.3 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Miro PF08477.8 EIE86499.1 - 3.9e-06 27.3 0.0 0.014 15.9 0.0 2.5 2 0 0 2 2 2 2 Miro-like protein Gtr1_RagA PF04670.7 EIE86499.1 - 8.8e-06 25.0 0.0 1.5e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region EF-hand_1 PF00036.27 EIE86499.1 - 9.3e-06 24.5 0.1 3.2e-05 22.9 0.1 2.0 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 EIE86499.1 - 0.001 18.7 0.0 0.0059 16.3 0.0 2.3 2 0 0 2 2 1 1 EF-hand domain EF-hand_7 PF13499.1 EIE86499.1 - 0.0011 19.0 0.0 0.003 17.6 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair FeoB_N PF02421.13 EIE86499.1 - 0.0039 16.4 0.1 0.16 11.2 0.1 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B EF-hand_8 PF13833.1 EIE86499.1 - 0.0062 16.1 0.3 0.14 11.8 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain pair SRPRB PF09439.5 EIE86499.1 - 0.013 14.7 0.1 0.69 9.1 0.0 3.0 3 1 0 3 3 3 0 Signal recognition particle receptor beta subunit UPF0079 PF02367.12 EIE86499.1 - 0.024 14.2 0.1 0.11 12.1 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 MobB PF03205.9 EIE86499.1 - 0.024 14.3 0.0 0.13 12.0 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 EIE86499.1 - 0.053 13.0 0.0 4.6 6.7 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 EIE86499.1 - 0.053 13.6 0.1 0.24 11.5 0.0 2.1 2 1 0 2 2 2 0 AAA domain Ras PF00071.17 EIE86499.1 - 0.063 12.6 0.3 7.3 5.9 0.1 2.3 2 0 0 2 2 2 0 Ras family AAA_28 PF13521.1 EIE86499.1 - 0.067 13.1 0.0 0.24 11.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF999 PF06198.6 EIE86499.1 - 0.1 12.3 0.1 0.26 11.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF999) VCBS PF13517.1 EIE86499.1 - 0.11 12.8 0.1 0.26 11.6 0.1 1.6 1 0 0 1 1 1 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 EIE86499.1 - 0.3 10.8 0.8 0.62 9.8 0.6 1.5 1 0 0 1 1 1 0 FG-GAP repeat F-box-like PF12937.2 EIE86501.1 - 3.3e-09 36.3 2.4 7.2e-09 35.2 1.7 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIE86501.1 - 2.5e-07 30.1 3.2 6e-07 28.9 2.2 1.7 1 0 0 1 1 1 1 F-box domain Kinase-like PF14531.1 EIE86502.1 - 4.1e-12 45.6 0.0 5.5e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.20 EIE86502.1 - 1.6e-09 37.2 0.1 7.8e-09 35.0 0.1 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE86502.1 - 0.0022 17.1 0.0 0.003 16.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase SOR_SNZ PF01680.12 EIE86503.1 - 6.9e-116 385.1 5.8 1.2e-115 384.4 4.0 1.3 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.9 EIE86503.1 - 5.4e-10 38.7 5.1 5.3e-07 28.9 0.1 2.4 2 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.12 EIE86503.1 - 8.1e-05 21.5 0.3 0.091 11.5 0.0 2.3 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) NanE PF04131.9 EIE86503.1 - 0.00056 18.9 0.4 0.076 11.9 0.0 2.5 2 0 0 2 2 2 2 Putative N-acetylmannosamine-6-phosphate epimerase His_biosynth PF00977.16 EIE86503.1 - 0.0038 16.5 0.9 0.21 10.8 0.0 2.9 2 1 1 3 3 3 1 Histidine biosynthesis protein IGPS PF00218.16 EIE86503.1 - 0.0084 15.1 0.1 0.088 11.8 0.0 2.4 3 0 0 3 3 3 1 Indole-3-glycerol phosphate synthase NMO PF03060.10 EIE86503.1 - 0.4 9.7 6.1 0.14 11.2 0.2 2.4 2 1 0 2 2 2 0 Nitronate monooxygenase RicinB_lectin_2 PF14200.1 EIE86504.1 - 1e-22 80.4 8.4 4.8e-12 46.1 0.6 2.1 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 EIE86504.1 - 1.3e-21 76.8 1.5 4.6e-12 46.0 0.1 2.1 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain dTDP_sugar_isom PF00908.12 EIE86504.1 - 0.091 12.0 0.9 0.96 8.7 0.1 2.0 1 1 1 2 2 2 0 dTDP-4-dehydrorhamnose 3,5-epimerase Receptor_2B4 PF11465.3 EIE86504.1 - 0.15 12.0 1.0 0.57 10.1 0.1 2.1 1 1 1 2 2 2 0 Natural killer cell receptor 2B4 Clathrin PF00637.15 EIE86505.1 - 4.2e-12 45.8 8.9 7.5e-10 38.5 0.4 3.0 2 1 0 2 2 2 2 Region in Clathrin and VPS Pep3_Vps18 PF05131.9 EIE86505.1 - 1.1e-07 31.3 7.4 1.2e-07 31.2 1.0 3.3 3 1 0 3 3 3 1 Pep3/Vps18/deep orange family Vps39_2 PF10367.4 EIE86505.1 - 4e-06 26.9 1.9 2.1e-05 24.6 1.3 2.2 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-RING_2 PF13639.1 EIE86505.1 - 0.00058 19.6 3.9 0.00058 19.6 2.7 2.7 3 0 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.1 EIE86505.1 - 0.00069 19.2 2.7 0.00069 19.2 1.8 2.4 2 0 0 2 2 2 1 zinc-RING finger domain DUF2175 PF09943.4 EIE86505.1 - 0.0069 16.4 1.7 0.096 12.7 1.3 3.0 1 1 1 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2175) zf-Apc11 PF12861.2 EIE86505.1 - 0.02 14.6 0.4 0.18 11.6 0.2 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger TPR_1 PF00515.23 EIE86505.1 - 0.026 14.1 1.7 3.1 7.5 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR PF01535.15 EIE86505.1 - 0.04 13.9 0.6 14 5.8 0.1 2.9 2 0 0 2 2 2 0 PPR repeat DUF1664 PF07889.7 EIE86505.1 - 0.076 12.8 4.2 3 7.6 0.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) zf-C3HC4 PF00097.20 EIE86505.1 - 0.3 10.7 2.7 1.4 8.6 1.9 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIE86505.1 - 0.65 10.0 8.3 0.097 12.7 2.0 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) MFS_1 PF07690.11 EIE86506.1 - 5.8e-45 153.5 28.2 4.2e-23 81.6 3.1 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIE86506.1 - 2.4e-11 42.8 21.7 6.5e-09 34.8 0.4 3.9 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_2 PF13347.1 EIE86506.1 - 1.1e-08 33.8 11.3 9.8e-06 24.2 0.7 2.4 2 1 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.2 EIE86506.1 - 3.8e-05 23.4 0.1 0.0012 18.6 0.1 2.8 2 0 0 2 2 2 1 MFS_1 like family DUF791 PF05631.9 EIE86506.1 - 0.0081 14.8 0.0 0.019 13.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF791) OATP PF03137.15 EIE86506.1 - 0.016 13.2 6.8 0.34 8.8 0.0 3.3 1 1 2 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family ATG22 PF11700.3 EIE86506.1 - 0.083 11.3 8.9 0.07 11.5 4.1 1.9 2 0 0 2 2 2 0 Vacuole effluxer Atg22 like LacY_symp PF01306.14 EIE86506.1 - 2.7 6.4 12.1 1.3 7.5 0.1 3.0 3 0 0 3 3 3 0 LacY proton/sugar symporter GHMP_kinases_N PF00288.21 EIE86507.1 - 2.1e-08 34.1 1.2 4.5e-08 33.0 0.8 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain DUF1819 PF08849.6 EIE86507.1 - 0.021 14.2 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 Putative inner membrane protein (DUF1819) Rhodanese PF00581.15 EIE86509.1 - 6.1e-08 32.9 0.0 6.8e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain RNA_pol_Rpb8 PF03870.10 EIE86510.1 - 1.2e-47 161.5 0.1 1.4e-47 161.3 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 Ribosomal_L1 PF00687.16 EIE86511.1 - 2.8e-11 43.2 0.1 3e-11 43.0 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family ART PF01129.13 EIE86511.1 - 0.057 12.5 0.0 0.057 12.5 0.0 1.2 1 0 0 1 1 1 0 NAD:arginine ADP-ribosyltransferase ADP_ribosyl_GH PF03747.9 EIE86513.1 - 5e-16 59.3 0.0 3.1e-09 37.0 0.0 2.0 1 1 1 2 2 2 2 ADP-ribosylglycohydrolase UBA_2 PF08587.6 EIE86513.1 - 0.086 13.0 0.2 6.8 6.9 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin associated domain (UBA) PPR_2 PF13041.1 EIE86514.1 - 1.4e-57 191.4 0.6 7.6e-12 45.0 0.0 11.6 5 4 7 12 12 12 10 PPR repeat family PPR PF01535.15 EIE86514.1 - 4.6e-42 139.0 5.6 0.00023 20.9 0.0 13.6 15 0 0 15 15 15 8 PPR repeat PPR_3 PF13812.1 EIE86514.1 - 1.4e-36 121.6 16.6 5.3e-06 26.3 0.0 14.0 16 0 0 16 16 16 7 Pentatricopeptide repeat domain PPR_1 PF12854.2 EIE86514.1 - 1.7e-30 104.1 6.1 4.2e-05 22.9 0.0 12.3 12 0 0 12 12 12 4 PPR repeat TPR_19 PF14559.1 EIE86514.1 - 1.8e-07 31.3 3.3 0.85 9.9 0.0 6.1 5 2 2 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.1 EIE86514.1 - 5.1e-05 23.8 12.6 1 10.0 0.1 7.1 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_12 PF13424.1 EIE86514.1 - 0.00042 20.1 4.6 6.2 6.8 0.0 6.5 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_14 PF13428.1 EIE86514.1 - 0.00046 20.5 18.9 6.8 7.6 0.0 9.0 7 1 3 10 10 10 2 Tetratricopeptide repeat B12-binding_2 PF02607.12 EIE86514.1 - 0.008 16.1 0.2 6.6 6.8 0.0 3.9 3 0 0 3 3 3 1 B12 binding domain ECSIT PF06239.6 EIE86514.1 - 0.01 14.7 0.0 0.13 11.0 0.0 2.6 3 0 0 3 3 3 0 Evolutionarily conserved signalling intermediate in Toll pathway ATG16 PF08614.6 EIE86515.1 - 0.01 15.6 0.7 1.6 8.5 0.1 2.2 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Ank_2 PF12796.2 EIE86516.1 - 4.6e-47 158.2 12.8 1.7e-16 60.3 1.9 4.9 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 EIE86516.1 - 1e-32 110.2 15.5 4.6e-05 23.0 0.2 8.6 9 0 0 9 9 9 8 Ankyrin repeat Ank_3 PF13606.1 EIE86516.1 - 2e-30 101.7 10.9 0.00033 20.6 0.2 8.6 9 0 0 9 9 9 6 Ankyrin repeat Ank_4 PF13637.1 EIE86516.1 - 5.3e-30 103.2 7.0 1.1e-08 35.3 0.0 6.0 2 2 6 8 8 8 8 Ankyrin repeats (many copies) Ank_5 PF13857.1 EIE86516.1 - 1.2e-27 95.2 14.7 2.6e-06 27.5 0.2 7.3 1 1 7 8 8 8 8 Ankyrin repeats (many copies) Ribosomal_L37ae PF01780.14 EIE86517.1 - 9.3e-41 137.6 10.8 1e-40 137.4 7.5 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.2 EIE86517.1 - 0.00069 19.3 2.2 0.001 18.8 1.5 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain A2L_zn_ribbon PF08792.5 EIE86517.1 - 0.0047 16.3 3.3 0.84 9.1 0.1 2.2 2 0 0 2 2 2 2 A2L zinc ribbon domain zf-FCS PF06467.9 EIE86517.1 - 0.027 14.0 2.2 0.75 9.4 0.1 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-H2C2_2 PF13465.1 EIE86517.1 - 0.08 13.2 1.4 2.5 8.5 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger double domain zf-BED PF02892.10 EIE86517.1 - 0.1 12.3 5.5 0.12 12.1 0.4 2.3 1 1 1 2 2 2 0 BED zinc finger Zn-ribbon_8 PF09723.5 EIE86517.1 - 0.17 11.8 1.7 0.9 9.5 0.1 2.2 2 0 0 2 2 2 0 Zinc ribbon domain Elf1 PF05129.8 EIE86517.1 - 0.27 10.9 2.7 0.5 10.0 1.9 1.5 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like zf-C2H2 PF00096.21 EIE86517.1 - 1.8 9.0 4.1 18 5.8 0.3 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type Ribosomal_L29 PF00831.18 EIE86518.1 - 1.2e-14 53.6 2.1 1.2e-14 53.6 1.4 2.2 2 1 0 2 2 2 1 Ribosomal L29 protein Ribosomal_S9 PF00380.14 EIE86518.1 - 0.12 12.6 3.1 0.21 11.8 2.2 1.5 1 1 0 1 1 1 0 Ribosomal protein S9/S16 CENP-B_N PF04218.8 EIE86518.1 - 0.76 9.2 4.7 4.3 6.8 0.0 3.0 3 0 0 3 3 3 0 CENP-B N-terminal DNA-binding domain HSP90 PF00183.13 EIE86519.1 - 8.6e-257 852.7 35.0 1.3e-256 852.1 24.3 1.3 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.21 EIE86519.1 - 1.2e-11 44.2 0.1 2.4e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EIE86519.1 - 8.7e-11 41.6 0.1 8.7e-11 41.6 0.1 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF399 PF04187.8 EIE86519.1 - 0.021 14.2 0.3 0.41 10.1 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function, DUF399 Pox_P35 PF03213.9 EIE86519.1 - 0.085 11.8 3.8 0.2 10.6 2.6 1.6 1 0 0 1 1 1 0 Poxvirus P35 protein VTC PF09359.5 EIE86520.1 - 2.7e-49 167.6 0.0 3.1e-46 157.6 0.0 3.1 2 1 0 2 2 2 2 VTC domain SPX PF03105.14 EIE86520.1 - 1.7e-23 83.8 8.9 1.6e-11 44.5 0.1 3.3 1 1 1 2 2 2 2 SPX domain DUF202 PF02656.10 EIE86520.1 - 1.9e-10 40.7 3.0 4e-10 39.7 2.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF202) VTC PF09359.5 EIE86521.1 - 1.1e-30 106.5 0.0 5e-30 104.4 0.0 2.0 1 1 0 1 1 1 1 VTC domain DUF202 PF02656.10 EIE86521.1 - 5.3e-06 26.5 0.2 1.9e-05 24.8 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SPX PF03105.14 EIE86521.1 - 0.0059 16.4 12.2 0.17 11.6 1.4 3.2 2 1 1 3 3 3 2 SPX domain Ribosomal_L6e PF01159.14 EIE86521.1 - 0.11 12.7 1.5 0.9 9.8 0.0 2.8 3 0 0 3 3 3 0 Ribosomal protein L6e HEAT_EZ PF13513.1 EIE86522.1 - 4.8e-24 84.1 15.6 2.6e-08 34.1 0.0 10.6 10 2 3 13 13 11 4 HEAT-like repeat HEAT PF02985.17 EIE86522.1 - 4e-23 79.3 12.1 0.00022 21.0 0.0 9.6 10 0 0 10 10 9 6 HEAT repeat HEAT_2 PF13646.1 EIE86522.1 - 1.9e-22 79.3 1.8 0.00023 21.3 0.0 6.2 4 2 2 6 6 6 6 HEAT repeats Vac14_Fab1_bd PF12755.2 EIE86522.1 - 5.1e-11 42.8 0.2 0.39 11.1 0.0 6.5 6 2 3 9 9 8 4 Vacuolar 14 Fab1-binding region IBN_N PF03810.14 EIE86522.1 - 3.6e-10 39.6 0.1 2.5e-09 36.9 0.0 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain Arm PF00514.18 EIE86522.1 - 6.7e-09 35.2 9.6 0.21 11.4 0.2 7.5 8 0 0 8 8 8 3 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.15 EIE86522.1 - 1.5e-07 30.1 0.5 0.0033 15.8 0.0 3.7 3 1 1 4 4 4 2 Adaptin N terminal region MMS19_C PF12460.3 EIE86522.1 - 0.00011 21.0 1.8 3.6 6.2 0.0 4.9 4 1 1 5 5 5 1 RNAPII transcription regulator C-terminal CLASP_N PF12348.3 EIE86522.1 - 0.00049 19.5 0.1 2.4 7.4 0.0 4.4 4 1 0 4 4 4 1 CLASP N terminal TIP120 PF08623.5 EIE86522.1 - 0.0017 17.9 0.0 2.2 7.8 0.0 3.8 3 0 0 3 3 3 1 TATA-binding protein interacting (TIP20) RasGEF_N_2 PF14663.1 EIE86522.1 - 0.0096 15.8 0.6 2.9 7.8 0.0 3.1 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RNA_pol_3_Rpc31 PF11705.3 EIE86522.1 - 1.9 8.3 12.5 3 7.7 8.7 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 XPC-binding PF09280.6 EIE86522.1 - 4.2 6.8 16.9 1.4 8.4 0.1 5.9 5 0 0 5 5 5 0 XPC-binding domain Retrotrans_gag PF03732.12 EIE86523.1 - 0.0028 17.7 0.1 0.0028 17.7 0.1 3.5 4 1 0 4 4 4 1 Retrotransposon gag protein IncA PF04156.9 EIE86523.1 - 0.21 11.1 5.0 0.39 10.3 3.5 1.4 1 0 0 1 1 1 0 IncA protein FlxA PF14282.1 EIE86523.1 - 0.21 11.5 5.8 2.3 8.2 4.0 2.6 1 1 0 1 1 1 0 FlxA-like protein HTH_Tnp_Tc3_2 PF01498.13 EIE86524.1 - 3.6e-11 42.9 1.1 3.6e-11 42.9 0.7 1.8 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 EIE86524.1 - 0.0006 19.9 0.3 0.0015 18.6 0.1 1.7 2 0 0 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.1 EIE86524.1 - 0.0043 16.6 0.1 0.011 15.4 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain DDE_3 PF13358.1 EIE86524.1 - 0.024 14.3 0.1 0.057 13.1 0.0 1.6 2 0 0 2 2 2 0 DDE superfamily endonuclease HTH_30 PF13556.1 EIE86524.1 - 0.028 13.9 0.0 0.092 12.3 0.0 1.7 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain HTH_32 PF13565.1 EIE86524.1 - 0.038 14.7 2.1 0.58 10.9 0.2 2.6 2 1 1 3 3 3 0 Homeodomain-like domain RecX PF02631.11 EIE86524.1 - 0.041 14.0 0.4 0.067 13.4 0.3 1.3 1 0 0 1 1 1 0 RecX family Med15 PF09606.5 EIE86525.1 - 0.042 12.0 14.6 0.06 11.5 10.1 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TFIIA PF03153.8 EIE86525.1 - 0.094 12.6 5.8 0.12 12.2 4.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FlgM PF04316.8 EIE86525.1 - 0.59 10.1 5.1 13 5.7 2.9 2.4 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM DEC-1_N PF04625.8 EIE86525.1 - 1 7.9 16.8 2 7.0 11.7 1.5 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Transposase_21 PF02992.9 EIE86526.1 - 5.9e-22 77.8 0.0 1.1e-21 76.9 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 DUF1258 PF06869.7 EIE86526.1 - 0.0026 16.8 0.0 0.0041 16.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) Nro1 PF12753.2 EIE86526.1 - 0.17 10.8 0.1 9.7 5.0 0.0 2.1 2 0 0 2 2 2 0 Nuclear pore complex subunit Nro1 HTH_Tnp_Tc3_2 PF01498.13 EIE86527.1 - 7.2e-08 32.3 0.9 9.9e-08 31.9 0.6 1.2 1 0 0 1 1 1 1 Transposase DUF520 PF04461.8 EIE86527.1 - 0.024 14.4 0.3 0.03 14.2 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF520) HTH_Tnp_Tc3_2 PF01498.13 EIE86529.1 - 1e-14 54.3 1.1 1.7e-14 53.5 0.7 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.1 EIE86529.1 - 0.0023 17.6 0.1 0.0047 16.6 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease Retrotrans_gag PF03732.12 EIE86530.1 - 2.4e-05 24.3 0.0 5.2e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein rve PF00665.21 EIE86531.1 - 1.1e-18 67.4 0.0 2.5e-18 66.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE86531.1 - 2.1e-16 59.9 0.4 4.8e-16 58.7 0.1 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE86531.1 - 1.7e-13 50.0 1.8 4.4e-13 48.6 1.3 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DDE_3 PF13358.1 EIE86533.1 - 4.6e-19 68.6 0.4 2.5e-18 66.2 0.0 2.3 3 0 0 3 3 3 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE86533.1 - 3.5e-11 43.0 0.5 8.5e-11 41.7 0.3 1.7 1 0 0 1 1 1 1 Transposase DUF515 PF04415.7 EIE86534.1 - 3.9 5.5 8.1 4.9 5.2 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) ADH_zinc_N PF00107.21 EIE86535.1 - 3.7e-17 62.0 2.3 3.7e-14 52.3 0.0 3.3 2 1 1 3 3 3 2 Zinc-binding dehydrogenase Pribosyltran PF00156.22 EIE86535.1 - 8.6e-15 54.5 0.1 2.2e-14 53.2 0.1 1.8 1 0 0 1 1 1 1 Phosphoribosyl transferase domain ADH_N PF08240.7 EIE86535.1 - 2.8e-09 36.6 0.0 7e-09 35.4 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EIE86535.1 - 0.024 15.5 0.1 0.13 13.1 0.0 2.3 2 1 0 2 2 2 0 Zinc-binding dehydrogenase PRTase_2 PF15609.1 EIE86535.1 - 0.13 11.5 0.1 0.25 10.6 0.1 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase Chlorosome_CsmC PF11098.3 EIE86536.1 - 1.3 8.7 8.3 1.4 8.5 5.7 1.2 1 0 0 1 1 1 0 Chlorosome envelope protein C Zds_C PF08632.5 EIE86537.1 - 4e-15 54.9 0.0 7.6e-15 54.0 0.0 1.4 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term zf-C2H2 PF00096.21 EIE86538.1 - 2.3e-12 46.4 7.0 7.3e-06 26.0 1.2 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIE86538.1 - 7e-11 41.8 10.3 8e-08 32.2 0.1 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EIE86538.1 - 1.5e-09 37.4 6.2 1.9e-05 24.6 0.9 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EIE86538.1 - 3.3e-05 23.9 1.1 0.00022 21.2 0.2 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EIE86538.1 - 0.0011 19.0 0.6 0.0011 19.0 0.4 2.1 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EIE86538.1 - 0.0013 18.5 2.5 0.08 12.8 0.3 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-BED PF02892.10 EIE86538.1 - 0.045 13.5 1.8 0.45 10.2 0.1 2.4 2 0 0 2 2 2 0 BED zinc finger Zn-ribbon_8 PF09723.5 EIE86538.1 - 0.064 13.2 0.3 9.6 6.2 0.0 2.5 2 0 0 2 2 2 0 Zinc ribbon domain zf-C2HC_2 PF13913.1 EIE86538.1 - 0.14 11.8 1.3 14 5.5 0.1 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-Di19 PF05605.7 EIE86538.1 - 0.21 11.7 1.7 0.81 9.8 1.1 1.9 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.1 EIE86538.1 - 2 8.7 6.0 25 5.3 1.1 2.9 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-DHHC PF01529.15 EIE86539.1 - 6.6e-20 71.2 11.2 9.6e-20 70.6 7.8 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase Glucos_trans_II PF14264.1 EIE86539.1 - 0.0023 17.0 3.6 0.0027 16.7 2.5 1.1 1 0 0 1 1 1 1 Glucosyl transferase GtrII HLH PF00010.21 EIE86540.1 - 0.00011 21.8 0.1 0.00025 20.6 0.0 1.6 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Mto2_bdg PF12808.2 EIE86540.1 - 0.085 12.9 2.4 0.92 9.6 0.0 2.3 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region CAP_GLY PF01302.20 EIE86541.1 - 1.5e-05 24.5 0.1 2.6e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 CAP-Gly domain Peptidase_C97 PF05903.9 EIE86542.1 - 1.2e-32 112.8 0.0 3.7e-32 111.1 0.0 1.9 1 1 0 1 1 1 1 PPPDE putative peptidase domain Thioredoxin PF00085.15 EIE86542.1 - 6e-18 64.4 0.0 1.1e-17 63.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin PUL PF08324.6 EIE86542.1 - 9.7e-16 57.3 4.7 1.5e-15 56.6 3.3 1.2 1 0 0 1 1 1 1 PUL domain Thioredoxin_2 PF13098.1 EIE86542.1 - 2e-06 27.9 0.2 2.6e-05 24.3 0.1 2.4 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EIE86542.1 - 0.00073 19.6 0.0 0.0047 17.0 0.0 2.2 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_4 PF13462.1 EIE86542.1 - 0.0055 16.7 0.0 4.3 7.3 0.0 2.7 1 1 1 2 2 2 2 Thioredoxin Glutaredoxin PF00462.19 EIE86542.1 - 0.0089 15.9 0.0 0.033 14.1 0.0 2.1 1 0 0 1 1 1 1 Glutaredoxin DSBA PF01323.15 EIE86542.1 - 0.014 15.0 0.0 0.45 10.0 0.0 2.6 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Thioredoxin_7 PF13899.1 EIE86542.1 - 0.033 14.2 0.0 0.074 13.0 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like Redoxin PF08534.5 EIE86542.1 - 0.13 11.7 0.0 3.3 7.2 0.0 2.2 2 0 0 2 2 2 0 Redoxin Nol1_Nop2_Fmu PF01189.12 EIE86543.1 - 1e-07 31.6 0.0 1.6e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 NOL1/NOP2/sun family FtsJ PF01728.14 EIE86543.1 - 0.044 13.7 0.0 0.07 13.1 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase SLX9 PF15341.1 EIE86543.1 - 0.081 13.3 3.7 0.16 12.3 2.5 1.9 1 1 0 1 1 1 0 Ribosome biogenesis protein SLX9 Mg_trans_NIPA PF05653.9 EIE86544.1 - 5.6e-27 94.4 9.2 1.6e-14 53.5 3.5 2.0 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.15 EIE86544.1 - 0.00032 20.7 2.7 0.00032 20.7 1.9 2.7 2 1 0 2 2 2 1 EamA-like transporter family EmrE PF13536.1 EIE86544.1 - 0.0072 16.5 3.9 0.0072 16.5 2.7 2.7 3 1 0 3 3 3 1 Multidrug resistance efflux transporter DUF843 PF05814.6 EIE86544.1 - 0.023 14.4 2.0 0.032 14.0 0.5 1.9 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) TPT PF03151.11 EIE86544.1 - 4.6 6.8 10.9 0.17 11.5 0.7 2.5 2 1 0 2 2 2 0 Triose-phosphate Transporter family HTH_23 PF13384.1 EIE86545.1 - 1.1e-05 24.8 0.0 1.7e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.1 EIE86545.1 - 0.00052 20.1 0.2 0.00082 19.5 0.2 1.4 1 1 0 1 1 1 1 Winged helix-turn helix HTH_15 PF12324.3 EIE86545.1 - 0.035 13.7 0.2 0.45 10.2 0.0 2.2 1 1 1 2 2 2 0 Helix-turn-helix domain of alkylmercury lyase Phage_antitermQ PF06530.7 EIE86545.1 - 0.039 13.5 0.2 6.8 6.2 0.0 2.2 2 0 0 2 2 2 0 Phage antitermination protein Q POP1 PF06978.6 EIE86545.1 - 0.044 13.4 1.2 0.063 12.9 0.9 1.2 1 0 0 1 1 1 0 Ribonucleases P/MRP protein subunit POP1 RCR PF12273.3 EIE86545.1 - 0.086 13.3 1.1 0.099 13.2 0.8 1.1 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red WD40 PF00400.27 EIE86546.1 - 1.5e-28 97.6 14.3 4.1e-09 35.9 0.2 6.9 5 2 1 6 6 6 4 WD domain, G-beta repeat ATG16 PF08614.6 EIE86546.1 - 1e-06 28.7 11.0 1e-06 28.7 7.6 1.6 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) eIF2A PF08662.6 EIE86546.1 - 7.6e-06 25.7 0.0 0.0021 17.8 0.0 3.0 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EIE86546.1 - 0.0062 14.7 4.3 4.6 5.2 0.0 3.4 2 2 1 4 4 4 3 Nucleoporin Nup120/160 Z1 PF10593.4 EIE86546.1 - 0.092 11.9 1.5 0.14 11.3 1.0 1.3 1 0 0 1 1 1 0 Z1 domain Borrelia_P83 PF05262.6 EIE86546.1 - 0.95 7.6 4.2 1.2 7.2 2.9 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Trs65 PF12735.2 EIE86547.1 - 1.4e-30 106.6 1.9 1.4e-30 106.6 1.3 2.3 2 1 0 2 2 2 1 TRAPP trafficking subunit Trs65 HTH_29 PF13551.1 EIE86551.1 - 0.1 12.7 0.0 0.21 11.7 0.0 1.6 1 1 0 1 1 1 0 Winged helix-turn helix DDE_3 PF13358.1 EIE86552.1 - 1.6e-09 37.6 2.4 3e-09 36.7 0.6 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE86553.1 - 2.9e-10 40.0 2.5 5.4e-10 39.2 0.7 2.1 2 0 0 2 2 2 1 Transposase HTH_Tnp_4 PF13613.1 EIE86553.1 - 0.0004 19.8 0.0 0.00081 18.8 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease DDE_3 PF13358.1 EIE86553.1 - 0.0017 18.1 0.0 0.0033 17.1 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_23 PF13384.1 EIE86553.1 - 0.0022 17.6 0.0 0.0067 16.0 0.0 1.9 1 0 0 1 1 1 1 Homeodomain-like domain DDE_3 PF13358.1 EIE86554.1 - 2.4e-18 66.3 0.1 6.2e-18 64.9 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE86554.1 - 4.8e-09 36.1 0.7 2e-08 34.1 0.7 2.0 2 1 0 2 2 2 1 Transposase HTH_Tnp_Tc3_2 PF01498.13 EIE86555.1 - 7.5e-14 51.5 0.9 1.3e-13 50.7 0.6 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.1 EIE86555.1 - 7.8e-05 22.4 0.1 0.00017 21.3 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_3 PF13358.1 EIE86556.1 - 5e-17 62.0 0.0 7.2e-17 61.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE86556.1 - 8.2e-10 38.6 2.1 5e-09 36.0 0.9 2.3 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.1 EIE86556.1 - 0.00047 19.7 0.0 0.0012 18.4 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_11 PF08279.7 EIE86556.1 - 0.00068 19.2 0.0 0.0019 17.8 0.0 1.7 1 0 0 1 1 1 1 HTH domain HTH_IclR PF09339.5 EIE86556.1 - 0.00075 19.0 0.0 0.0015 18.0 0.0 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_7 PF02796.10 EIE86556.1 - 0.0032 17.2 0.2 0.061 13.1 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_32 PF13565.1 EIE86556.1 - 0.0039 17.9 0.8 3.2 8.6 0.0 2.9 2 0 0 2 2 2 1 Homeodomain-like domain HTH_38 PF13936.1 EIE86556.1 - 0.0073 15.8 0.0 0.016 14.7 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_36 PF13730.1 EIE86556.1 - 0.0082 16.2 0.4 0.25 11.5 0.0 2.9 3 0 0 3 3 3 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.7 EIE86556.1 - 0.011 15.1 0.0 0.03 13.7 0.0 1.7 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_AsnC-type PF13404.1 EIE86556.1 - 0.015 14.8 0.0 0.032 13.7 0.0 1.5 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_29 PF13551.1 EIE86556.1 - 0.017 15.2 0.1 0.11 12.6 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_4 PF13613.1 EIE86556.1 - 0.02 14.4 0.0 0.3 10.6 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix of DDE superfamily endonuclease UPF0122 PF04297.9 EIE86556.1 - 0.04 13.9 0.2 0.11 12.5 0.0 1.7 2 0 0 2 2 2 0 Putative helix-turn-helix protein, YlxM / p13 like Sigma70_r4 PF04545.11 EIE86556.1 - 0.041 13.2 0.0 0.087 12.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_24 PF13412.1 EIE86556.1 - 0.042 13.2 0.0 0.095 12.1 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_17 PF12728.2 EIE86556.1 - 0.049 13.9 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain GerE PF00196.14 EIE86556.1 - 0.096 12.0 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family Chromo PF00385.19 EIE86557.1 - 3.3e-11 42.6 0.4 7.2e-11 41.5 0.3 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain YcgR_2 PF12945.2 EIE86557.1 - 0.083 12.7 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Flagellar protein YcgR S1_2 PF13509.1 EIE86557.1 - 0.1 12.5 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 S1 domain ALMS_motif PF15309.1 EIE86557.1 - 0.36 10.6 8.7 0.57 10.0 0.1 2.3 2 0 0 2 2 2 0 ALMS motif HTH_Tnp_Tc3_2 PF01498.13 EIE86559.1 - 3e-05 23.9 0.2 0.00012 22.0 0.1 2.0 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 EIE86559.1 - 0.0042 17.2 0.1 0.0065 16.6 0.1 1.4 1 1 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EIE86559.1 - 0.0059 16.2 0.1 0.01 15.4 0.1 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_30 PF13556.1 EIE86559.1 - 0.084 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain RVT_1 PF00078.22 EIE86560.1 - 1.5e-07 31.0 0.1 2.5e-07 30.2 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.12 EIE86561.1 - 0.00027 20.9 0.5 0.00081 19.4 0.1 2.0 2 0 0 2 2 2 1 Retrotransposon gag protein DDE_3 PF13358.1 EIE86562.1 - 1.9e-10 40.6 0.1 2.2e-10 40.4 0.1 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease NUDIX_4 PF14815.1 EIE86562.1 - 0.056 12.8 0.1 0.062 12.7 0.1 1.2 1 0 0 1 1 1 0 NUDIX domain HTH_23 PF13384.1 EIE86563.1 - 9.4e-05 21.9 0.1 0.00014 21.3 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_7 PF02796.10 EIE86563.1 - 0.00059 19.6 0.3 0.0017 18.1 0.1 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase GcrA PF07750.6 EIE86563.1 - 0.0041 17.3 0.1 0.0045 17.1 0.1 1.2 1 0 0 1 1 1 1 GcrA cell cycle regulator HTH_Tnp_1 PF01527.15 EIE86563.1 - 0.11 12.4 0.0 0.36 10.8 0.0 1.7 1 1 1 2 2 2 0 Transposase HTH_Tnp_Tc3_2 PF01498.13 EIE86563.1 - 0.25 11.3 3.9 0.92 9.6 0.3 3.0 2 1 1 3 3 3 0 Transposase rve PF00665.21 EIE86564.1 - 1.9e-22 79.6 0.0 4.7e-22 78.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE86564.1 - 8.3e-16 57.9 0.1 1.7e-15 56.9 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.12 EIE86564.1 - 8.4e-09 35.3 0.1 2.4e-08 33.9 0.1 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein Chromo PF00385.19 EIE86564.1 - 4.3e-08 32.6 0.1 1e-07 31.5 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.1 EIE86564.1 - 2.3e-05 24.7 0.0 5.6e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.5 EIE86564.1 - 0.00044 19.5 1.6 0.0015 17.8 1.1 2.0 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger gag-asp_proteas PF13975.1 EIE86564.1 - 0.023 14.5 0.0 0.058 13.2 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease PF09668.5 EIE86564.1 - 0.066 12.7 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease SWIM PF04434.12 EIE86565.1 - 1.2e-05 24.6 0.4 1.9e-05 24.0 0.3 1.3 1 0 0 1 1 1 1 SWIM zinc finger DUF2874 PF11396.3 EIE86565.1 - 0.097 12.6 0.4 0.24 11.4 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2874) Exo_endo_phos_2 PF14529.1 EIE86567.1 - 2.2e-14 53.0 0.0 6.8e-14 51.5 0.0 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EIE86567.1 - 4.9e-06 26.6 0.2 1.3e-05 25.3 0.1 1.7 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF972 PF06156.8 EIE86567.1 - 8e-05 22.9 1.1 0.00015 22.0 0.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF972) TSC22 PF01166.13 EIE86567.1 - 0.00013 21.8 0.5 0.00027 20.8 0.4 1.5 1 0 0 1 1 1 1 TSC-22/dip/bun family DUF904 PF06005.7 EIE86567.1 - 0.016 15.4 1.5 0.037 14.3 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DivIC PF04977.10 EIE86567.1 - 0.17 11.3 0.8 0.31 10.5 0.6 1.4 1 0 0 1 1 1 0 Septum formation initiator RVT_1 PF00078.22 EIE86568.1 - 2.5e-28 98.9 0.0 3.9e-28 98.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HTH_Tnp_Tc3_2 PF01498.13 EIE86569.1 - 8.9e-10 38.4 1.9 7.4e-09 35.5 0.6 2.3 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.1 EIE86569.1 - 2.2e-08 33.9 2.4 2.8e-08 33.6 0.8 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_23 PF13384.1 EIE86569.1 - 0.00016 21.1 0.0 0.00042 19.8 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_IclR PF09339.5 EIE86569.1 - 0.00048 19.6 0.0 0.00092 18.7 0.0 1.4 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_11 PF08279.7 EIE86569.1 - 0.00054 19.5 0.1 0.0014 18.2 0.0 1.7 2 0 0 2 2 1 1 HTH domain HTH_7 PF02796.10 EIE86569.1 - 0.0011 18.8 0.3 0.027 14.3 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_32 PF13565.1 EIE86569.1 - 0.0013 19.4 0.9 2.7 8.8 0.0 2.7 2 0 0 2 2 2 2 Homeodomain-like domain HTH_29 PF13551.1 EIE86569.1 - 0.0051 16.9 0.1 0.057 13.5 0.0 2.2 2 0 0 2 2 2 1 Winged helix-turn helix HTH_38 PF13936.1 EIE86569.1 - 0.006 16.1 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.7 EIE86569.1 - 0.011 15.2 0.0 0.019 14.4 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_AsnC-type PF13404.1 EIE86569.1 - 0.011 15.2 0.0 0.021 14.3 0.0 1.4 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain UPF0122 PF04297.9 EIE86569.1 - 0.023 14.7 0.1 0.043 13.8 0.0 1.4 1 0 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like HTH_24 PF13412.1 EIE86569.1 - 0.027 13.8 0.0 0.058 12.8 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Sigma70_r4 PF04545.11 EIE86569.1 - 0.028 13.7 0.0 0.054 12.8 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_36 PF13730.1 EIE86569.1 - 0.029 14.4 0.0 0.14 12.2 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_17 PF12728.2 EIE86569.1 - 0.033 14.4 0.0 0.06 13.5 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain GerE PF00196.14 EIE86569.1 - 0.039 13.2 0.1 0.11 11.7 0.0 1.7 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family Terminase_5 PF06056.7 EIE86569.1 - 0.058 12.9 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) HTH_Tnp_4 PF13613.1 EIE86569.1 - 0.088 12.3 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease Trp_repressor PF01371.14 EIE86569.1 - 0.12 12.2 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Trp repressor protein HTH_6 PF01418.12 EIE86569.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family DDE_3 PF13358.1 EIE86570.1 - 1e-17 64.2 0.1 1.8e-17 63.4 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE86570.1 - 0.0022 18.0 0.0 0.0069 16.4 0.0 1.9 1 0 0 1 1 1 1 Transposase rve PF00665.21 EIE86570.1 - 0.0061 16.6 0.0 0.016 15.3 0.0 1.9 1 1 0 1 1 1 1 Integrase core domain HTH_7 PF02796.10 EIE86570.1 - 0.019 14.8 0.1 3.1 7.7 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_23 PF13384.1 EIE86570.1 - 0.039 13.6 0.0 0.08 12.6 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.13 EIE86572.1 - 5.7e-06 26.3 0.9 1.2e-05 25.3 0.5 1.7 1 1 0 1 1 1 1 Transposase rve PF00665.21 EIE86573.1 - 4.8e-18 65.4 0.0 1.4e-17 63.8 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE86573.1 - 5.1e-13 48.8 0.2 1.1e-12 47.7 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.5 EIE86573.1 - 0.0012 18.1 0.1 0.0012 18.1 0.1 2.3 2 0 0 2 2 2 1 His(2)-Cys(2) zinc finger Asp_protease_2 PF13650.1 EIE86573.1 - 0.0043 17.5 0.0 0.013 16.0 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EIE86573.1 - 0.049 13.4 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF2759 PF10958.3 EIE86573.1 - 0.28 10.7 0.8 0.63 9.6 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2759) DDE_Tnp_IS1595 PF12762.2 EIE86574.1 - 2.1e-07 30.8 0.1 5.2e-07 29.6 0.1 1.6 1 0 0 1 1 1 1 ISXO2-like transposase domain ESAG1 PF03238.8 EIE86574.1 - 0.014 14.7 3.0 0.03 13.6 0.5 2.1 2 0 0 2 2 2 0 ESAG protein DUF202 PF02656.10 EIE86576.1 - 3.9e-12 46.1 4.0 3.9e-12 46.1 2.8 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF1049 PF06305.6 EIE86576.1 - 0.049 13.1 0.4 0.049 13.1 0.3 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1049) CoA_binding_3 PF13727.1 EIE86576.1 - 0.41 10.4 2.5 0.5 10.1 1.7 1.2 1 0 0 1 1 1 0 CoA-binding domain Alg14 PF08660.6 EIE86577.1 - 4.3e-36 124.4 0.0 6.5e-22 78.3 0.0 2.0 1 1 1 2 2 2 2 Oligosaccharide biosynthesis protein Alg14 like Peptidase_S9 PF00326.16 EIE86578.1 - 8.1e-38 129.7 0.5 1.4e-37 129.0 0.4 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EIE86578.1 - 1.7e-08 34.3 0.1 3.1e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 EIE86578.1 - 2.3e-05 23.0 0.0 0.0004 18.9 0.0 2.3 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.2 EIE86578.1 - 9e-05 22.4 1.8 0.00027 20.8 1.3 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family PD40 PF07676.7 EIE86578.1 - 0.015 14.9 0.6 22 4.8 0.0 3.9 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Asp_Glu_race_2 PF14669.1 EIE86579.1 - 0.013 14.8 0.0 0.02 14.1 0.0 1.2 1 0 0 1 1 1 0 Putative aspartate racemase GAS2 PF02187.12 EIE86579.1 - 0.12 12.2 0.1 0.4 10.4 0.0 1.9 2 0 0 2 2 2 0 Growth-Arrest-Specific Protein 2 Domain eIF-5_eIF-2B PF01873.12 EIE86580.1 - 9.3e-46 154.5 0.7 1.4e-45 154.0 0.5 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.7 EIE86580.1 - 0.0027 16.9 0.4 0.0058 15.9 0.3 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding IF2_N PF04760.10 EIE86580.1 - 0.011 15.4 0.0 0.029 14.0 0.0 1.7 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region zf-HYPF PF07503.7 EIE86580.1 - 0.1 12.0 0.2 14 5.1 0.0 2.4 2 0 0 2 2 2 0 HypF finger SART-1 PF03343.8 EIE86580.1 - 0.11 10.8 30.6 0.16 10.2 21.2 1.3 1 0 0 1 1 1 0 SART-1 family Hid1 PF12722.2 EIE86580.1 - 5.4 4.5 13.2 6.2 4.3 9.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RRM_1 PF00076.17 EIE86582.1 - 1.8e-13 49.9 0.0 3.8e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE86582.1 - 6.1e-11 42.1 0.0 9.7e-11 41.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE86582.1 - 1.2e-05 25.0 0.0 1.9e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) eIF-4B PF06273.6 EIE86582.1 - 0.00052 18.8 26.3 0.00062 18.6 8.4 3.0 2 1 0 2 2 2 2 Plant specific eukaryotic initiation factor 4B GRP PF07172.6 EIE86582.1 - 0.015 15.7 7.2 1.2 9.6 1.0 2.2 2 0 0 2 2 2 0 Glycine rich protein family SusD PF07980.6 EIE86583.1 - 0.053 13.0 2.4 0.063 12.7 1.6 1.0 1 0 0 1 1 1 0 SusD family RRM_1 PF00076.17 EIE86585.1 - 2.5e-32 110.3 0.4 1.8e-14 53.0 0.0 4.3 4 1 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE86585.1 - 4.2e-24 84.2 0.0 1.8e-09 37.4 0.0 3.8 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE86585.1 - 1e-19 70.0 0.2 2.6e-07 30.3 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Laminin_G_1 PF00054.18 EIE86585.1 - 0.16 12.0 0.0 9.5 6.2 0.0 2.2 2 0 0 2 2 2 0 Laminin G domain DUF1777 PF08648.7 EIE86585.1 - 1.6 8.4 34.3 2.6 7.7 23.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) Glyco_hydro_28 PF00295.12 EIE86586.1 - 8.2e-73 245.1 24.8 1.1e-72 244.7 17.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Aromatic_hydrox PF11723.3 EIE86587.1 - 0.065 12.5 0.3 0.095 11.9 0.2 1.2 1 0 0 1 1 1 0 Homotrimeric ring hydroxylase Imm33 PF15580.1 EIE86587.1 - 0.13 11.7 0.7 0.87 9.1 0.1 2.1 2 0 0 2 2 2 0 Immunity protein 33 Methyltransf_11 PF08241.7 EIE86588.1 - 1.3e-10 41.6 0.0 4.5e-10 39.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIE86588.1 - 6.8e-06 25.3 0.0 1e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EIE86588.1 - 8.1e-05 22.2 0.1 0.00015 21.4 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIE86588.1 - 0.00025 20.7 0.0 0.00038 20.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIE86588.1 - 0.00031 21.1 0.0 0.00086 19.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_8 PF05148.10 EIE86588.1 - 0.0011 18.6 0.0 0.0014 18.2 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_25 PF13649.1 EIE86588.1 - 0.0044 17.3 0.0 0.021 15.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain CheR PF01739.13 EIE86588.1 - 0.031 13.5 0.0 0.045 13.0 0.0 1.2 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_2 PF00891.13 EIE86588.1 - 0.087 11.9 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 O-methyltransferase Ribosomal_L18ae PF01775.12 EIE86590.1 - 1.9e-58 195.7 2.4 2.4e-58 195.4 1.6 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain GATA PF00320.22 EIE86591.1 - 4.3e-12 45.1 6.2 9.8e-12 44.0 4.3 1.6 1 0 0 1 1 1 1 GATA zinc finger zf-C3HC4_2 PF13923.1 EIE86591.1 - 0.071 13.1 0.1 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1168 PF06658.7 EIE86591.1 - 1.3 8.5 15.3 0.29 10.6 1.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) La PF05383.12 EIE86592.1 - 1.3e-19 69.7 0.0 2.6e-19 68.7 0.0 1.5 1 0 0 1 1 1 1 La domain RRM_1 PF00076.17 EIE86592.1 - 9.1e-08 31.6 0.7 2.3e-07 30.3 0.4 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE86592.1 - 1.4e-06 28.1 0.3 4.2e-06 26.6 0.1 2.0 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE86592.1 - 1.7e-06 27.7 0.1 3.6e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Hid1 PF12722.2 EIE86592.1 - 3.1 5.3 10.6 3.4 5.2 7.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF908 PF06012.7 EIE86592.1 - 7 5.8 8.4 9.1 5.4 5.8 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Zn_clus PF00172.13 EIE86593.1 - 3e-06 27.0 12.3 4.8e-06 26.3 8.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MAPEG PF01124.13 EIE86594.1 - 0.00085 18.9 6.7 0.00091 18.8 4.7 1.0 1 0 0 1 1 1 1 MAPEG family DUF1145 PF06611.7 EIE86594.1 - 0.15 11.6 2.4 0.4 10.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1145) Helicase_C PF00271.26 EIE86595.1 - 0.00014 21.6 0.0 0.00074 19.3 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RCC_reductase PF06405.6 EIE86595.1 - 0.036 12.9 0.0 0.073 12.0 0.0 1.4 1 0 0 1 1 1 0 Red chlorophyll catabolite reductase (RCC reductase) Methyltransf_11 PF08241.7 EIE86596.1 - 2.2e-13 50.4 0.0 4.2e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIE86596.1 - 1.5e-10 40.8 0.1 3.6e-10 39.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIE86596.1 - 6.6e-10 38.9 0.0 9.7e-10 38.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIE86596.1 - 3.1e-09 37.1 0.0 8e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIE86596.1 - 9.8e-08 31.3 0.1 3.9e-07 29.4 0.0 1.9 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EIE86596.1 - 6.6e-07 29.6 0.0 2e-06 28.0 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIE86596.1 - 9.8e-06 26.1 0.0 4.4e-05 24.0 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 EIE86596.1 - 0.00016 20.8 0.1 0.0041 16.1 0.0 2.4 1 1 1 2 2 2 1 Putative methyltransferase Methyltransf_2 PF00891.13 EIE86596.1 - 0.00028 20.1 0.0 0.0004 19.6 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_8 PF05148.10 EIE86596.1 - 0.00045 19.9 0.0 0.0011 18.6 0.0 1.5 1 1 0 1 1 1 1 Hypothetical methyltransferase MetW PF07021.7 EIE86596.1 - 0.00074 18.9 0.1 0.0011 18.4 0.1 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW CMAS PF02353.15 EIE86596.1 - 0.0011 18.0 0.0 0.0016 17.5 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 EIE86596.1 - 0.0013 18.7 0.0 0.008 16.2 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain FmrO PF07091.6 EIE86596.1 - 0.0048 15.9 0.0 0.025 13.5 0.0 1.9 2 0 0 2 2 2 1 Ribosomal RNA methyltransferase (FmrO) MTS PF05175.9 EIE86596.1 - 0.0067 15.8 0.0 0.014 14.7 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain PCMT PF01135.14 EIE86596.1 - 0.058 12.9 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MRP-S28 PF10213.4 EIE86598.1 - 3.4e-38 130.5 0.7 3.4e-38 130.5 0.5 1.7 2 0 0 2 2 2 1 Mitochondrial ribosomal subunit protein G-patch PF01585.18 EIE86599.1 - 0.0065 16.2 2.6 0.014 15.1 1.8 1.6 1 0 0 1 1 1 1 G-patch domain Toprim_2 PF13155.1 EIE86599.1 - 0.051 13.8 0.4 0.077 13.3 0.3 1.4 1 1 0 1 1 1 0 Toprim-like Fib_alpha PF08702.5 EIE86599.1 - 0.072 13.2 2.6 0.082 13.0 1.8 1.0 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family EntA_Immun PF08951.5 EIE86600.1 - 0.035 14.2 1.7 0.035 14.2 1.1 2.5 3 0 0 3 3 3 0 Enterocin A Immunity SVS_QK PF10578.4 EIE86600.1 - 0.25 11.7 0.3 0.25 11.7 0.2 1.9 2 0 0 2 2 2 0 Seminal vesicle protein repeat Glyco_hydro_17 PF00332.13 EIE86602.1 - 1e-14 54.2 1.9 1.5e-13 50.5 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 T2SM_b PF10741.4 EIE86602.1 - 0.037 13.6 0.0 10 5.7 0.0 2.3 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M subtype b Acetyltransf_1 PF00583.19 EIE86603.1 - 0.0019 18.1 0.0 0.0035 17.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EIE86603.1 - 0.0044 17.1 0.1 0.011 15.8 0.1 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EIE86603.1 - 0.07 12.8 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Glyco_transf_15 PF01793.11 EIE86604.1 - 1.2e-89 300.4 8.6 1.4e-89 300.3 6.0 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Spond_N PF06468.8 EIE86604.1 - 0.0028 17.3 0.1 0.004 16.8 0.1 1.2 1 0 0 1 1 1 1 Spondin_N PS_Dcarbxylase PF02666.10 EIE86605.1 - 1.9e-57 193.8 0.0 3e-57 193.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.25 EIE86605.1 - 6.9e-29 99.5 0.2 5.7e-16 58.1 0.1 2.6 2 0 0 2 2 2 2 C2 domain CDC45 PF02724.9 EIE86605.1 - 5.2 4.9 11.6 8.7 4.2 8.0 1.3 1 0 0 1 1 1 0 CDC45-like protein T2SK PF03934.8 EIE86607.1 - 0.082 12.0 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein K Aminotran_4 PF01063.14 EIE86608.1 - 7.4e-17 61.5 0.0 1.4e-16 60.6 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class IV ING PF12998.2 EIE86609.1 - 0.0008 19.6 1.3 0.00088 19.5 0.1 1.6 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding NusB PF01029.13 EIE86609.1 - 0.061 13.3 0.6 0.088 12.7 0.1 1.5 2 0 0 2 2 2 0 NusB family ACT_7 PF13840.1 EIE86610.1 - 4.8e-27 93.2 0.0 4.5e-16 58.1 0.0 2.2 2 0 0 2 2 2 2 ACT domain DUF2007 PF09413.5 EIE86610.1 - 0.073 12.9 0.0 2.4 8.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF2007) Lipase_3 PF01764.20 EIE86611.1 - 1.7e-18 66.5 0.0 3.3e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 EIE86611.1 - 0.013 15.1 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_6 PF12697.2 EIE86611.1 - 0.013 15.3 0.2 0.13 12.1 0.1 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIE86611.1 - 0.056 13.2 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family Telomere_reg-2 PF10193.4 EIE86612.1 - 5.2e-23 81.4 0.0 1.6e-22 79.8 0.0 1.9 1 0 0 1 1 1 1 Telomere length regulation protein MCM PF00493.18 EIE86614.1 - 2.2e-133 444.1 0.0 2.9e-133 443.7 0.0 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EIE86614.1 - 1.5e-20 73.8 0.3 6e-20 71.9 0.1 2.1 3 0 0 3 3 3 1 MCM N-terminal domain AAA_5 PF07728.9 EIE86614.1 - 1.1e-07 31.6 0.0 3.1e-07 30.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EIE86614.1 - 1.6e-07 30.7 0.0 0.0002 20.5 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EIE86614.1 - 0.00014 21.4 0.0 0.019 14.5 0.0 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EIE86614.1 - 0.00055 19.4 0.1 1.9 7.9 0.0 3.0 3 0 0 3 3 3 2 Sigma-54 interaction domain AAA_16 PF13191.1 EIE86614.1 - 0.012 15.5 0.7 1.4 8.9 0.0 3.6 3 1 1 4 4 4 0 AAA ATPase domain Sigma54_activ_2 PF14532.1 EIE86614.1 - 0.046 13.7 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain eIF-3_zeta PF05091.7 EIE86615.1 - 6e-181 602.5 0.1 7e-181 602.3 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) E1-E2_ATPase PF00122.15 EIE86616.1 - 6.6e-61 205.2 3.6 1.2e-60 204.3 2.5 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EIE86616.1 - 6.8e-28 98.5 0.0 1.7e-27 97.2 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 EIE86616.1 - 8.7e-20 71.0 1.1 8.7e-20 71.0 0.7 2.5 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase_like2 PF13246.1 EIE86616.1 - 3.2e-17 62.2 0.1 7e-17 61.1 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EIE86616.1 - 1.3e-16 61.3 0.0 5.5e-16 59.2 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EIE86616.1 - 4.1e-09 35.7 0.0 6.9e-08 31.8 0.0 2.4 1 1 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EIE86616.1 - 1.6e-05 24.6 0.3 3.4e-05 23.5 0.2 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase AAA_23 PF13476.1 EIE86618.1 - 2.7e-14 53.9 0.3 2.7e-14 53.9 0.2 1.5 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 EIE86618.1 - 3e-11 42.9 0.5 3.8e-11 42.6 0.1 1.4 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EIE86618.1 - 2.6e-06 27.5 0.7 3.3e-06 27.2 0.1 1.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EIE86618.1 - 4.5e-06 26.0 0.0 8.9e-06 25.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.1 EIE86618.1 - 8.3e-05 21.7 0.1 0.0003 19.9 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 EIE86618.1 - 0.0025 17.2 0.0 0.0043 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EIE86618.1 - 0.0047 17.2 1.5 0.006 16.8 0.3 1.8 2 1 0 2 2 2 1 ABC transporter AAA_13 PF13166.1 EIE86618.1 - 0.015 13.8 0.1 0.018 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EIE86618.1 - 0.016 15.4 0.0 0.028 14.5 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EIE86618.1 - 0.022 14.5 0.1 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 Part of AAA domain IstB_IS21 PF01695.12 EIE86618.1 - 0.046 13.1 0.0 0.059 12.7 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF258 PF03193.11 EIE86618.1 - 0.049 12.8 0.1 0.096 11.8 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function, DUF258 AAA_17 PF13207.1 EIE86618.1 - 0.1 13.4 0.8 0.23 12.2 0.6 1.7 1 1 0 1 1 1 0 AAA domain MutS_V PF00488.16 EIE86618.1 - 0.12 11.7 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 MutS domain V AAA_22 PF13401.1 EIE86618.1 - 0.13 12.4 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EIE86618.1 - 0.13 11.8 0.1 0.21 11.2 0.1 1.3 1 0 0 1 1 1 0 NACHT domain SMC_N PF02463.14 EIE86619.1 - 7.9e-08 31.7 0.4 1.3e-07 31.0 0.3 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain GAS PF13851.1 EIE86619.1 - 3.8e-06 26.2 16.9 3.8e-06 26.2 11.7 4.6 3 1 1 5 5 5 1 Growth-arrest specific micro-tubule binding DUF904 PF06005.7 EIE86619.1 - 0.0044 17.2 0.8 0.0044 17.2 0.5 5.6 4 2 1 5 5 5 1 Protein of unknown function (DUF904) DUF4140 PF13600.1 EIE86619.1 - 0.0077 16.6 2.3 0.0077 16.6 1.6 5.0 3 2 1 5 5 5 1 N-terminal domain of unknown function (DUF4140) BLOC1_2 PF10046.4 EIE86619.1 - 0.024 14.7 21.1 0.69 10.0 0.2 4.6 3 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 AAA_13 PF13166.1 EIE86619.1 - 0.1 11.0 36.6 0.06 11.8 9.0 2.8 2 1 1 3 3 3 0 AAA domain Sec20 PF03908.8 EIE86619.1 - 0.2 11.3 6.7 2.4 7.9 0.4 3.3 1 1 1 2 2 2 0 Sec20 DUF211 PF02680.9 EIE86619.1 - 0.21 11.4 1.6 8.8 6.2 0.0 2.8 3 0 0 3 3 3 0 Uncharacterized ArCR, COG1888 FUSC PF04632.7 EIE86619.1 - 0.57 8.5 6.8 1.1 7.5 4.7 1.5 1 0 0 1 1 1 0 Fusaric acid resistance protein family DivIC PF04977.10 EIE86619.1 - 1.3 8.6 32.5 0.28 10.7 2.7 4.7 4 1 1 5 5 4 0 Septum formation initiator Baculo_PEP_C PF04513.7 EIE86619.1 - 1.3 8.8 14.5 0.86 9.4 1.0 4.4 4 1 1 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Atg14 PF10186.4 EIE86619.1 - 2.4 7.0 34.2 1.8 7.3 3.9 3.5 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 WXG100 PF06013.7 EIE86619.1 - 2.6 8.1 10.7 25 4.9 0.0 4.4 3 1 1 4 4 4 0 Proteins of 100 residues with WXG Laminin_II PF06009.7 EIE86619.1 - 2.9 7.6 21.8 3.5 7.3 5.3 4.2 3 1 0 4 4 4 0 Laminin Domain II TMPIT PF07851.8 EIE86619.1 - 3.2 6.7 20.0 0.13 11.3 6.4 3.1 2 1 1 3 3 3 0 TMPIT-like protein TBPIP PF07106.8 EIE86619.1 - 3.3 7.2 36.1 2.2 7.8 1.3 4.6 2 1 0 4 4 4 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) FlaC_arch PF05377.6 EIE86619.1 - 3.3 7.6 12.7 10 6.1 0.3 4.9 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) Spc24 PF08286.6 EIE86619.1 - 6.4 6.4 23.4 3.1 7.5 6.9 4.1 3 1 1 4 4 4 0 Spc24 subunit of Ndc80 NPV_P10 PF05531.7 EIE86619.1 - 6.5 7.0 16.5 19 5.5 0.0 4.9 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein MFS_1 PF07690.11 EIE86620.1 - 5.2e-40 137.2 69.1 2.4e-30 105.4 28.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIE86620.1 - 5.5e-11 41.7 36.3 1.1e-10 40.7 12.1 2.7 1 1 1 2 2 2 2 Sugar (and other) transporter DUF3290 PF11694.3 EIE86620.1 - 0.068 12.8 0.2 0.3 10.7 0.1 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) Vpu PF00558.14 EIE86620.1 - 0.56 9.7 3.9 0.21 11.1 0.1 2.3 2 0 0 2 2 2 0 Vpu protein LRR_6 PF13516.1 EIE86621.1 - 0.0018 18.1 5.9 2.4 8.4 0.0 4.3 3 1 1 4 4 4 1 Leucine Rich repeat LRR_4 PF12799.2 EIE86621.1 - 0.0078 15.8 5.4 0.23 11.1 0.0 3.0 1 1 2 3 3 3 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EIE86621.1 - 0.06 13.3 2.9 4.3 7.7 0.8 3.7 3 1 0 3 3 3 0 Leucine Rich Repeat LRR_8 PF13855.1 EIE86621.1 - 0.08 12.7 5.3 0.14 11.9 0.0 2.5 1 1 1 2 2 2 0 Leucine rich repeat LRR_7 PF13504.1 EIE86621.1 - 6 7.5 7.3 20 5.9 0.0 4.4 4 2 1 5 5 5 0 Leucine rich repeat U-box PF04564.10 EIE86622.1 - 0.002 18.0 0.0 0.0046 16.8 0.0 1.6 1 0 0 1 1 1 1 U-box domain SR-25 PF10500.4 EIE86622.1 - 0.0022 17.5 6.8 0.0022 17.5 4.7 2.4 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein DUF1296 PF06972.6 EIE86622.1 - 0.0037 17.1 0.8 0.017 15.0 0.4 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1296) Myb_DNA-binding PF00249.26 EIE86622.1 - 0.006 16.6 0.0 0.019 15.0 0.0 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain C9orf72-like PF15019.1 EIE86623.1 - 0.021 14.0 0.4 0.071 12.3 0.0 1.9 2 0 0 2 2 2 0 C9orf72-like protein family PaRep2b PF07775.6 EIE86623.1 - 0.054 11.7 0.2 0.059 11.5 0.1 1.1 1 0 0 1 1 1 0 PaRep2b protein DUF2115 PF09888.4 EIE86623.1 - 0.15 12.1 1.5 3.8 7.6 1.1 2.0 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) DUF2360 PF10152.4 EIE86624.1 - 0.49 10.6 3.2 6.1 7.1 2.2 2.3 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) F-box-like PF12937.2 EIE86625.1 - 2.1e-05 24.1 0.3 4.9e-05 22.9 0.2 1.6 1 0 0 1 1 1 1 F-box-like DUF2183 PF09949.4 EIE86625.1 - 0.039 13.8 0.1 0.13 12.2 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2183) Peroxin-22 PF12827.2 EIE86626.1 - 0.0015 18.2 0.4 0.0021 17.7 0.3 1.4 1 1 0 1 1 1 1 Peroxisomal biogenesis protein family DUF3918 PF13056.1 EIE86627.1 - 0.15 11.4 0.1 0.25 10.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3918) zf-CCCH_2 PF14608.1 EIE86628.1 - 0.00014 21.7 17.3 0.041 13.8 6.5 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type SIR2 PF02146.12 EIE86629.1 - 5.6e-38 130.4 0.0 8.5e-38 129.8 0.0 1.3 1 0 0 1 1 1 1 Sir2 family AAA PF00004.24 EIE86631.1 - 9.3e-42 142.3 0.0 2.5e-41 140.9 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EIE86631.1 - 5.3e-06 26.6 0.0 0.0005 20.2 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EIE86631.1 - 7.3e-06 25.7 0.1 4.9e-05 23.0 0.0 2.5 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EIE86631.1 - 6.5e-05 22.9 0.0 0.00016 21.7 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.9 EIE86631.1 - 0.0002 21.2 0.0 0.00069 19.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 EIE86631.1 - 0.00069 18.6 0.0 0.0012 17.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 EIE86631.1 - 0.0015 19.3 0.2 0.0048 17.7 0.1 2.1 2 1 0 2 2 1 1 AAA domain AAA_19 PF13245.1 EIE86631.1 - 0.0032 17.2 0.1 0.0067 16.1 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 EIE86631.1 - 0.0032 16.5 0.0 0.0064 15.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 EIE86631.1 - 0.01 15.7 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EIE86631.1 - 0.011 14.8 0.0 0.019 14.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Arch_ATPase PF01637.13 EIE86631.1 - 0.012 15.3 0.2 5.2 6.7 0.0 2.9 2 1 1 3 3 3 0 Archaeal ATPase AAA_33 PF13671.1 EIE86631.1 - 0.012 15.4 0.0 0.025 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EIE86631.1 - 0.015 15.1 0.0 0.036 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 EIE86631.1 - 0.016 15.2 0.0 0.038 14.0 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain KaiC PF06745.8 EIE86631.1 - 0.022 13.8 0.1 1.4 8.0 0.0 2.4 2 0 0 2 2 2 0 KaiC AAA_3 PF07726.6 EIE86631.1 - 0.025 14.1 0.0 0.05 13.1 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EIE86631.1 - 0.03 14.4 0.0 0.08 13.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.12 EIE86631.1 - 0.031 13.6 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.1 EIE86631.1 - 0.033 14.4 0.0 0.12 12.7 0.0 2.0 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 EIE86631.1 - 0.038 12.7 0.0 0.078 11.6 0.0 1.4 1 0 0 1 1 1 0 TIP49 C-terminus Mg_chelatase PF01078.16 EIE86631.1 - 0.052 12.7 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 EIE86631.1 - 0.052 13.1 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EIE86631.1 - 0.08 12.4 0.0 0.2 11.1 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_25 PF13481.1 EIE86631.1 - 0.12 11.7 0.1 0.44 9.9 0.0 1.9 1 1 1 2 2 2 0 AAA domain Methyltransf_11 PF08241.7 EIE86632.1 - 1.1e-11 45.0 0.0 2.5e-11 43.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIE86632.1 - 1.7e-11 44.1 0.0 6.5e-11 42.2 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIE86632.1 - 2.1e-09 37.1 0.0 7.4e-09 35.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIE86632.1 - 3.2e-09 37.0 0.0 9.5e-09 35.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIE86632.1 - 1.2e-07 32.3 0.0 4.3e-07 30.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EIE86632.1 - 1.2e-07 30.9 0.0 1.8e-06 27.1 0.0 2.3 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_12 PF08242.7 EIE86632.1 - 4.8e-07 30.1 0.0 1e-06 29.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EIE86632.1 - 5.5e-05 22.6 0.0 0.0001 21.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 EIE86632.1 - 0.00018 20.6 0.0 0.00034 19.8 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.6 EIE86632.1 - 0.0012 17.6 0.1 0.0056 15.4 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) Methyltransf_26 PF13659.1 EIE86632.1 - 0.0076 16.2 0.0 0.068 13.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EIE86632.1 - 0.0087 15.7 0.0 0.019 14.5 0.0 1.5 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_32 PF13679.1 EIE86632.1 - 0.05 13.2 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.9 EIE86632.1 - 0.096 11.8 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB PCMT PF01135.14 EIE86632.1 - 0.11 11.9 0.0 0.28 10.6 0.0 1.6 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Allantoicase PF03561.10 EIE86633.1 - 1.9e-30 105.3 0.0 3.6e-14 52.5 0.0 2.7 2 1 1 3 3 3 2 Allantoicase repeat KIF1B PF12423.3 EIE86633.1 - 0.019 14.9 0.0 0.04 13.9 0.0 1.5 1 0 0 1 1 1 0 Kinesin protein 1B DDE_3 PF13358.1 EIE86638.1 - 6.8e-06 25.8 0.0 8.8e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DENN PF02141.16 EIE86639.1 - 2e-35 122.1 0.0 4.3e-27 95.0 0.1 3.1 2 1 1 3 3 3 2 DENN (AEX-3) domain dDENN PF03455.14 EIE86639.1 - 1.6e-14 53.7 1.1 4e-14 52.4 0.8 1.7 1 0 0 1 1 1 1 dDENN domain uDENN PF03456.13 EIE86639.1 - 0.00032 20.6 0.4 0.0064 16.4 0.3 3.0 1 1 1 2 2 2 1 uDENN domain C1_1 PF00130.17 EIE86639.1 - 0.12 12.0 6.2 0.3 10.8 4.3 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) LSM PF01423.17 EIE86640.1 - 2.3e-16 59.0 2.0 3e-16 58.6 1.4 1.2 1 0 0 1 1 1 1 LSM domain BPL_C PF02237.12 EIE86640.1 - 0.069 12.8 0.1 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain Asp PF00026.18 EIE86642.1 - 3.4e-77 259.7 0.7 5.1e-77 259.2 0.5 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIE86642.1 - 6.1e-10 39.2 0.0 1.7e-08 34.5 0.2 3.0 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EIE86642.1 - 0.0028 17.1 0.4 0.1 12.1 0.3 2.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 EIE86642.1 - 0.024 15.1 3.8 5 7.6 0.0 3.7 3 1 0 3 3 3 0 Aspartyl protease gag-asp_proteas PF13975.1 EIE86642.1 - 0.063 13.1 0.2 4.1 7.2 0.0 2.5 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease dCMP_cyt_deam_1 PF00383.17 EIE86643.1 - 0.018 14.6 0.1 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region Pescadillo_N PF06732.6 EIE86644.1 - 1.3e-121 405.1 3.8 1.3e-121 405.1 2.6 1.9 2 1 0 2 2 2 1 Pescadillo N-terminus BRCT PF00533.21 EIE86644.1 - 1.4e-07 31.5 0.0 4.1e-07 30.0 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain EmrE PF13536.1 EIE86645.1 - 7.7e-07 29.2 2.8 7.7e-07 29.2 1.9 3.5 3 1 1 4 4 4 1 Multidrug resistance efflux transporter EamA PF00892.15 EIE86645.1 - 2.7e-05 24.2 41.8 0.0002 21.3 8.3 3.2 3 1 1 4 4 4 2 EamA-like transporter family TPT PF03151.11 EIE86645.1 - 0.0049 16.5 11.6 0.0049 16.5 8.0 3.1 2 1 0 2 2 2 1 Triose-phosphate Transporter family FixQ PF05545.6 EIE86645.1 - 0.026 14.1 0.0 0.026 14.1 0.0 3.3 5 0 0 5 5 5 0 Cbb3-type cytochrome oxidase component FixQ DUF3188 PF11384.3 EIE86645.1 - 0.3 10.7 2.1 10 5.7 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3188) DRY_EERY PF09750.4 EIE86646.1 - 3.5e-24 85.2 0.1 7e-24 84.2 0.1 1.5 1 0 0 1 1 1 1 Alternative splicing regulator Abhydrolase_5 PF12695.2 EIE86646.1 - 1.6e-08 34.4 0.0 2.6e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIE86646.1 - 0.00039 20.3 0.0 0.001 19.0 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family RHH_1 PF01402.16 EIE86647.1 - 0.0077 16.0 0.0 0.026 14.4 0.0 2.0 1 0 0 1 1 1 1 Ribbon-helix-helix protein, copG family SpoIIIAH PF12685.2 EIE86647.1 - 6.3 6.2 11.0 0.18 11.3 3.0 1.7 2 0 0 2 2 2 0 SpoIIIAH-like protein Seipin PF06775.9 EIE86648.1 - 1.6e-38 132.2 0.1 2.1e-38 131.8 0.1 1.1 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) Tox-HNH-HHH PF15637.1 EIE86649.1 - 0.0083 15.9 0.0 0.021 14.5 0.0 1.7 2 0 0 2 2 2 1 HNH/Endo VII superfamily nuclease toxin with a HHH motif Elf1 PF05129.8 EIE86649.1 - 0.038 13.6 0.6 0.11 12.1 0.4 1.8 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like DUF4428 PF14471.1 EIE86649.1 - 0.12 12.1 3.0 0.71 9.6 0.4 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4428) DUF3844 PF12955.2 EIE86650.1 - 4.8e-12 45.8 15.7 5.1e-12 45.8 9.0 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF3844) EGF_2 PF07974.8 EIE86650.1 - 0.0013 18.8 17.6 0.0028 17.7 12.2 1.6 1 0 0 1 1 1 1 EGF-like domain DUF2888 PF11135.3 EIE86650.1 - 0.095 12.4 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2888) EGF PF00008.22 EIE86650.1 - 0.16 11.9 8.1 0.32 11.0 5.6 1.5 1 0 0 1 1 1 0 EGF-like domain EGF_CA PF07645.10 EIE86650.1 - 0.37 10.8 13.5 1.2 9.1 9.4 1.8 1 0 0 1 1 1 0 Calcium-binding EGF domain EGF_3 PF12947.2 EIE86650.1 - 5.6 7.0 13.9 11 6.1 9.7 1.5 1 0 0 1 1 1 0 EGF domain Myb_DNA-bind_6 PF13921.1 EIE86651.1 - 0.0002 21.4 0.1 0.00047 20.2 0.1 1.7 1 1 1 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EIE86651.1 - 0.0091 16.0 0.1 0.051 13.6 0.0 2.1 2 1 0 2 2 2 1 Myb-like DNA-binding domain Calcipressin PF04847.7 EIE86651.1 - 0.058 12.9 1.1 5.6 6.4 0.2 2.1 2 0 0 2 2 2 0 Calcipressin TPR_11 PF13414.1 EIE86652.1 - 6.2e-14 51.4 6.6 5.2e-05 22.8 0.3 4.5 3 2 0 4 4 4 3 TPR repeat TPR_19 PF14559.1 EIE86652.1 - 2.8e-11 43.5 7.3 0.00023 21.4 0.2 3.9 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EIE86652.1 - 4.5e-11 41.7 11.2 0.043 13.7 0.1 7.9 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.1 EIE86652.1 - 4.9e-10 39.8 1.4 0.013 16.2 0.0 4.5 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 EIE86652.1 - 1.4e-09 37.3 1.7 0.02 15.0 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 EIE86652.1 - 7.4e-09 35.4 7.2 0.15 12.0 0.0 4.9 4 1 1 5 5 5 4 Tetratricopeptide repeat Apc3 PF12895.2 EIE86652.1 - 1e-07 31.9 8.0 0.03 14.4 0.6 3.6 3 1 0 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EIE86652.1 - 1.1e-07 31.8 1.8 0.86 10.4 0.0 5.2 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 EIE86652.1 - 1.6e-05 24.3 9.5 4.8 6.9 0.0 6.9 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_8 PF13181.1 EIE86652.1 - 0.00036 20.1 8.6 8.5 6.4 0.0 5.8 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_20 PF14561.1 EIE86652.1 - 0.01 15.9 4.6 1.4 9.0 0.2 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat DUF1996 PF09362.5 EIE86652.1 - 0.1 12.2 0.1 0.18 11.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1996) Streptin-Immun PF11083.3 EIE86652.1 - 9.4 6.2 9.1 2.8 7.9 0.3 3.2 4 0 0 4 4 4 0 Lantibiotic streptin immunity protein DDE_3 PF13358.1 EIE86653.1 - 2e-21 76.2 0.1 5.9e-21 74.7 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_1 PF03184.14 EIE86653.1 - 0.0046 16.1 0.1 0.0098 15.0 0.1 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Terminase_1 PF03354.10 EIE86653.1 - 0.032 12.6 0.0 0.052 11.9 0.0 1.3 1 0 0 1 1 1 0 Phage Terminase HTH_Tnp_Tc3_2 PF01498.13 EIE86653.1 - 0.044 13.8 0.8 0.1 12.6 0.0 2.1 2 0 0 2 2 2 0 Transposase DUF2422 PF10337.4 EIE86657.1 - 0.00049 19.0 10.5 0.058 12.1 7.3 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2422) DUF2421 PF10334.4 EIE86658.1 - 6e-13 48.9 0.0 7.7e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2421) FUSC_2 PF13515.1 EIE86658.1 - 0.00019 21.3 2.9 0.00031 20.6 2.0 1.4 1 0 0 1 1 1 1 Fusaric acid resistance protein-like Ribosomal_L6e PF01159.14 EIE86660.1 - 6.3e-37 126.1 0.3 6.3e-37 126.1 0.2 1.6 2 0 0 2 2 2 1 Ribosomal protein L6e Ribosomal_L6e_N PF03868.10 EIE86660.1 - 6.5e-11 41.9 1.0 6.5e-11 41.9 0.7 2.2 2 0 0 2 2 2 1 Ribosomal protein L6, N-terminal domain KOW PF00467.24 EIE86660.1 - 0.0039 16.8 0.3 0.011 15.4 0.0 1.9 2 0 0 2 2 2 1 KOW motif Apc13p PF05839.6 EIE86661.1 - 0.00036 20.4 0.2 0.00044 20.1 0.1 1.2 1 0 0 1 1 1 1 Apc13p protein PP1_inhibitor PF05361.7 EIE86661.1 - 0.097 12.3 0.1 0.11 12.1 0.1 1.1 1 0 0 1 1 1 0 PKC-activated protein phosphatase-1 inhibitor GPI-anchored PF10342.4 EIE86662.1 - 0.0013 19.1 0.0 0.0016 18.9 0.0 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family TPT PF03151.11 EIE86663.1 - 4.1e-14 52.5 4.0 4.1e-14 52.5 2.8 2.6 1 1 1 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EIE86663.1 - 6.8e-09 35.0 14.6 9.3e-09 34.6 10.1 1.1 1 0 0 1 1 1 1 UAA transporter family PHO4 PF01384.15 EIE86663.1 - 0.014 14.0 9.9 0.043 12.4 0.8 3.0 2 1 0 2 2 2 0 Phosphate transporter family DUF3290 PF11694.3 EIE86663.1 - 0.13 11.9 1.9 0.7 9.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) NCA2 PF08637.5 EIE86664.1 - 8.8e-61 205.3 1.2 1.4e-60 204.6 0.8 1.3 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 PAP_central PF04928.12 EIE86664.1 - 0.0045 15.8 0.0 1.6 7.4 0.0 2.2 1 1 1 2 2 2 2 Poly(A) polymerase central domain Syja_N PF02383.13 EIE86666.1 - 2e-74 250.2 2.4 4.6e-59 199.7 0.1 2.5 2 1 1 3 3 3 2 SacI homology domain Exo_endo_phos PF03372.18 EIE86666.1 - 1.9e-17 64.0 0.0 4.7e-16 59.4 0.0 2.8 2 1 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family zf-CCHC PF00098.18 EIE86669.1 - 8.6e-07 28.6 3.5 1.4e-06 27.9 2.4 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.1 EIE86669.1 - 0.01 15.2 4.7 0.026 13.9 3.2 1.7 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.1 EIE86669.1 - 0.03 14.0 0.6 0.03 14.0 0.4 2.0 2 0 0 2 2 2 0 Zinc knuckle zf-MYND PF01753.13 EIE86669.1 - 0.2 11.5 2.5 0.34 10.8 1.7 1.3 1 0 0 1 1 1 0 MYND finger DUF4578 PF15147.1 EIE86669.1 - 2.6 8.4 8.8 1.3 9.4 4.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4578) tRNA-synt_2b PF00587.20 EIE86670.1 - 2e-67 226.1 0.3 3.5e-67 225.3 0.2 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EIE86670.1 - 2.3e-22 78.7 0.0 9.8e-22 76.7 0.0 2.2 1 0 0 1 1 1 1 Anticodon binding domain Sigma70_r4_2 PF08281.7 EIE86671.1 - 0.12 11.8 0.1 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 dCMP_cyt_deam_1 PF00383.17 EIE86672.1 - 8e-05 22.2 0.0 0.00015 21.3 0.0 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Lipase_3 PF01764.20 EIE86673.1 - 5.9e-38 129.6 0.0 1.7e-37 128.1 0.0 1.8 3 0 0 3 3 3 1 Lipase (class 3) DUF2974 PF11187.3 EIE86673.1 - 7.4e-06 25.4 0.1 1.6e-05 24.4 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.2 EIE86673.1 - 0.016 15.1 0.0 0.089 12.6 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIE86673.1 - 0.082 12.6 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family BRO1 PF03097.13 EIE86674.1 - 3.5e-57 193.8 0.1 8.3e-57 192.6 0.1 1.6 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EIE86674.1 - 1.5e-54 184.9 13.3 2.6e-54 184.2 9.3 1.2 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV BRO1 PF03097.13 EIE86675.1 - 2.3e-17 62.8 0.2 2.6e-17 62.6 0.1 1.0 1 0 0 1 1 1 1 BRO1-like domain PI3_PI4_kinase PF00454.22 EIE86676.1 - 4e-49 167.2 0.5 1.1e-48 165.8 0.0 2.1 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 EIE86676.1 - 3.7e-11 42.2 0.1 7.9e-11 41.1 0.1 1.6 1 0 0 1 1 1 1 FATC domain TPR_12 PF13424.1 EIE86676.1 - 0.036 14.0 2.0 5.6 6.9 0.1 3.0 1 1 1 2 2 2 0 Tetratricopeptide repeat Polysacc_deac_1 PF01522.16 EIE86678.1 - 8.6e-28 96.4 0.1 1.7e-27 95.4 0.1 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase XAP5 PF04921.9 EIE86679.1 - 7.8e-89 297.3 8.8 7.8e-89 297.3 6.1 2.1 1 1 1 2 2 2 1 XAP5, circadian clock regulator Parvo_coat PF00740.13 EIE86679.1 - 5.1 5.9 7.0 6.8 5.5 4.8 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 Pirin PF02678.11 EIE86680.1 - 1.4e-32 111.6 0.0 2.8e-32 110.7 0.0 1.5 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.8 EIE86680.1 - 3.4e-29 100.9 0.0 5.9e-28 96.9 0.0 2.3 3 0 0 3 3 3 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 EIE86680.1 - 0.011 15.1 1.6 0.042 13.3 0.2 2.4 3 0 0 3 3 3 0 Cupin domain PseudoU_synth_1 PF01416.15 EIE86681.1 - 9.7e-32 109.5 0.0 1e-19 70.8 0.0 2.3 2 0 0 2 2 2 2 tRNA pseudouridine synthase Cyclin PF08613.6 EIE86682.1 - 2.1e-08 34.6 0.0 2.6e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EIE86682.1 - 8.8e-06 25.3 0.0 1.1e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF4218 PF13960.1 EIE86684.1 - 1.8e-06 27.4 0.0 3.8e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Mt_ATP-synt_D PF05873.7 EIE86685.1 - 3.3e-18 65.8 5.2 4.3e-18 65.4 3.6 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) PEP-utilisers_N PF05524.8 EIE86685.1 - 9.7e-05 22.1 4.2 0.0094 15.7 0.5 2.1 1 1 1 2 2 2 2 PEP-utilising enzyme, N-terminal Vps51 PF08700.6 EIE86685.1 - 0.007 16.1 5.0 0.34 10.7 0.4 2.4 1 1 1 2 2 2 1 Vps51/Vps67 TMF_TATA_bd PF12325.3 EIE86685.1 - 0.012 15.2 1.0 0.012 15.2 0.7 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding AAA_13 PF13166.1 EIE86685.1 - 0.02 13.3 10.1 0.025 13.0 7.0 1.0 1 0 0 1 1 1 0 AAA domain Cypo_polyhedrin PF05865.6 EIE86685.1 - 0.021 14.0 0.0 0.023 13.9 0.0 1.1 1 0 0 1 1 1 0 Cypovirus polyhedrin protein Baculo_PEP_C PF04513.7 EIE86685.1 - 0.03 14.1 2.5 0.043 13.6 1.7 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Peptidase_M75 PF09375.5 EIE86685.1 - 0.049 12.9 3.8 0.032 13.5 1.3 1.6 1 1 0 1 1 1 0 Imelysin IFT57 PF10498.4 EIE86685.1 - 0.064 11.9 8.1 0.079 11.6 5.6 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Laminin_II PF06009.7 EIE86685.1 - 0.072 12.8 10.4 0.064 13.0 1.6 2.4 1 1 2 3 3 3 0 Laminin Domain II DUF4613 PF15390.1 EIE86685.1 - 0.079 11.1 3.0 0.094 10.8 2.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) DUF327 PF03885.8 EIE86685.1 - 0.093 12.5 6.2 0.69 9.7 4.3 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF327) DUF1845 PF08900.6 EIE86685.1 - 0.094 11.9 2.1 0.12 11.6 0.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1845) HTH_5 PF01022.15 EIE86685.1 - 0.11 12.2 0.1 0.42 10.3 0.0 2.0 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family SPX PF03105.14 EIE86685.1 - 0.12 12.1 6.6 0.3 10.8 4.5 1.6 1 1 1 2 2 2 0 SPX domain WXG100 PF06013.7 EIE86685.1 - 0.14 12.1 3.7 2.3 8.2 0.7 2.4 2 1 0 2 2 2 0 Proteins of 100 residues with WXG FlaC_arch PF05377.6 EIE86685.1 - 0.27 11.1 6.6 14 5.7 0.0 3.0 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Phage_GP20 PF06810.6 EIE86685.1 - 0.29 10.5 12.6 0.4 10.1 0.4 2.1 1 1 1 2 2 2 0 Phage minor structural protein GP20 V_ATPase_I PF01496.14 EIE86685.1 - 0.31 8.8 7.9 0.63 7.8 5.5 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Glutaredoxin2_C PF04399.8 EIE86685.1 - 0.32 10.5 6.6 0.33 10.5 0.7 2.3 1 1 1 2 2 2 0 Glutaredoxin 2, C terminal domain TMPIT PF07851.8 EIE86685.1 - 0.32 10.0 7.1 0.53 9.2 4.6 1.6 1 1 1 2 2 2 0 TMPIT-like protein DUF4600 PF15372.1 EIE86685.1 - 0.33 11.1 7.3 5.7 7.1 1.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4600) Dor1 PF04124.7 EIE86685.1 - 0.35 9.2 5.6 0.97 7.8 3.9 1.7 1 1 0 1 1 1 0 Dor1-like family DUF1664 PF07889.7 EIE86685.1 - 0.35 10.6 5.0 0.35 10.6 1.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF885 PF05960.6 EIE86685.1 - 0.35 9.9 3.6 0.49 9.4 2.5 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) COG2 PF06148.6 EIE86685.1 - 0.44 10.4 5.8 0.52 10.1 2.8 1.9 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF2802 PF10975.3 EIE86685.1 - 0.52 10.1 4.2 1.7 8.4 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) DUF148 PF02520.12 EIE86685.1 - 0.52 10.1 10.2 0.36 10.6 4.8 2.1 1 1 0 2 2 2 0 Domain of unknown function DUF148 Prominin PF05478.6 EIE86685.1 - 0.55 7.7 6.1 0.62 7.5 4.2 1.1 1 0 0 1 1 1 0 Prominin DUF4140 PF13600.1 EIE86685.1 - 0.6 10.5 9.2 0.28 11.6 1.4 2.4 1 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) CDC37_N PF03234.9 EIE86685.1 - 0.61 10.3 6.0 0.89 9.8 4.1 1.3 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding DUF2937 PF11157.3 EIE86685.1 - 0.72 9.1 3.1 0.78 9.0 0.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2937) Fib_alpha PF08702.5 EIE86685.1 - 0.8 9.8 8.4 1 9.4 5.5 1.4 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Spc7 PF08317.6 EIE86685.1 - 0.87 8.1 11.3 2 6.9 7.7 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein Spc24 PF08286.6 EIE86685.1 - 1.4 8.6 6.1 3.1 7.5 1.1 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 ApoLp-III PF07464.6 EIE86685.1 - 1.5 8.7 11.7 4 7.4 7.4 1.8 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) TPR_MLP1_2 PF07926.7 EIE86685.1 - 1.5 8.5 12.8 23 4.7 3.9 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein tRNA-synt_His PF13393.1 EIE86685.1 - 1.7 7.6 4.3 5 6.0 3.0 1.7 1 1 0 1 1 1 0 Histidyl-tRNA synthetase Prefoldin_2 PF01920.15 EIE86685.1 - 1.7 8.4 10.7 0.62 9.8 2.0 2.6 3 0 0 3 3 2 0 Prefoldin subunit DUF2408 PF10303.4 EIE86685.1 - 1.7 8.7 6.5 9.9 6.2 4.5 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) NPV_P10 PF05531.7 EIE86685.1 - 1.9 8.7 11.2 15 5.9 4.2 2.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4200 PF13863.1 EIE86685.1 - 1.9 8.4 11.2 0.77 9.7 2.6 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) Ribosomal_L29 PF00831.18 EIE86685.1 - 2 8.1 7.6 1.9 8.2 1.3 2.5 2 1 0 2 2 2 0 Ribosomal L29 protein IncA PF04156.9 EIE86685.1 - 2.2 7.8 11.5 1.8 8.1 3.6 2.1 1 1 1 2 2 2 0 IncA protein DUF1090 PF06476.7 EIE86685.1 - 2.2 7.9 10.5 2 8.1 1.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1090) DivIC PF04977.10 EIE86685.1 - 2.3 7.7 9.1 3.2 7.3 1.8 2.6 2 0 0 2 2 2 0 Septum formation initiator Adeno_PIX PF03955.9 EIE86685.1 - 2.5 8.6 4.4 3.2 8.3 1.0 2.1 1 1 1 2 2 2 0 Adenovirus hexon-associated protein (IX) Uso1_p115_C PF04871.8 EIE86685.1 - 2.7 7.9 9.3 0.38 10.6 3.2 1.8 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF948 PF06103.6 EIE86685.1 - 2.9 7.8 6.9 6.6 6.6 2.4 2.5 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) Prefoldin PF02996.12 EIE86685.1 - 3.3 7.3 11.1 1.3e+02 2.2 6.6 2.7 1 1 0 1 1 1 0 Prefoldin subunit BLOC1_2 PF10046.4 EIE86685.1 - 3.4 7.8 9.7 0.73 10.0 2.1 2.4 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Seryl_tRNA_N PF02403.17 EIE86685.1 - 4.1 7.4 11.5 17 5.4 6.2 2.6 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Syntaxin PF00804.20 EIE86685.1 - 4.1 7.6 9.5 26 5.0 6.5 2.1 1 1 0 1 1 1 0 Syntaxin Med9 PF07544.8 EIE86685.1 - 4.5 7.0 8.6 14 5.4 2.6 2.8 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 DUF2570 PF10828.3 EIE86685.1 - 7.7 6.1 13.1 4.9 6.8 0.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) APG9 PF04109.11 EIE86686.1 - 1.2e-63 215.3 0.6 1.4e-63 215.0 0.4 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 DUF3664 PF12406.3 EIE86687.1 - 0.094 13.3 2.8 0.12 13.0 1.9 1.1 1 0 0 1 1 1 0 Surface protein AIP3 PF03915.8 EIE86688.1 - 9.8e-49 166.3 28.2 1.7e-48 165.6 19.6 1.3 1 1 0 1 1 1 1 Actin interacting protein 3 Citrate_synt PF00285.16 EIE86688.1 - 0.089 11.5 4.9 0.13 10.9 3.4 1.4 1 0 0 1 1 1 0 Citrate synthase TBPIP PF07106.8 EIE86688.1 - 0.78 9.2 28.1 0.06 12.9 3.9 3.3 1 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Lectin_N PF03954.9 EIE86688.1 - 2.8 7.3 11.4 0.056 12.8 1.3 2.6 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain DDE_3 PF13358.1 EIE86690.1 - 6.1e-21 74.6 0.0 1.3e-20 73.6 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE86690.1 - 1.1e-15 57.4 1.9 2.8e-15 56.1 0.3 2.3 3 0 0 3 3 2 1 Transposase HTH_29 PF13551.1 EIE86690.1 - 2.7e-06 27.4 0.2 8.6e-06 25.8 0.2 1.9 2 0 0 2 2 1 1 Winged helix-turn helix HTH_38 PF13936.1 EIE86690.1 - 1.2e-05 24.7 0.1 3.3e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.1 EIE86690.1 - 7.7e-05 22.2 0.1 0.0028 17.2 0.0 2.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.1 EIE86690.1 - 9.7e-05 23.0 3.0 0.02 15.6 0.1 3.7 4 0 0 4 4 3 1 Homeodomain-like domain Sigma70_r4_2 PF08281.7 EIE86690.1 - 0.00085 18.7 0.8 0.024 14.0 0.0 3.1 4 0 0 4 4 4 1 Sigma-70, region 4 HTH_28 PF13518.1 EIE86690.1 - 0.0013 18.7 0.0 0.0056 16.6 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_21 PF13276.1 EIE86690.1 - 0.0015 18.5 0.1 0.13 12.2 0.0 2.8 3 0 0 3 3 3 1 HTH-like domain HTH_7 PF02796.10 EIE86690.1 - 0.0022 17.7 1.1 0.1 12.4 0.0 2.8 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase rve PF00665.21 EIE86690.1 - 0.0045 17.0 0.0 0.014 15.4 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain LacI PF00356.16 EIE86690.1 - 0.017 14.6 1.7 2.8 7.6 0.2 2.7 3 0 0 3 3 3 0 Bacterial regulatory proteins, lacI family HTH_Tnp_4 PF13613.1 EIE86690.1 - 0.022 14.2 0.1 0.057 12.9 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease CPSase_L_D3 PF02787.14 EIE86690.1 - 0.058 13.1 0.0 0.14 11.8 0.0 1.7 2 0 0 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain HTH_36 PF13730.1 EIE86690.1 - 0.075 13.1 0.4 4.1 7.6 0.0 2.9 3 0 0 3 3 2 0 Helix-turn-helix domain Sigma70_r4 PF04545.11 EIE86690.1 - 0.1 11.9 0.2 0.79 9.0 0.0 2.6 4 0 0 4 4 4 0 Sigma-70, region 4 HTH_Tnp_ISL3 PF13542.1 EIE86690.1 - 0.17 11.0 2.8 8.4 5.6 0.0 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 HTH_17 PF12728.2 EIE86690.1 - 0.22 11.7 2.5 15 5.9 0.1 3.2 3 0 0 3 3 3 0 Helix-turn-helix domain zf-trcl PF13451.1 EIE86690.1 - 0.74 9.4 3.7 0.56 9.8 0.3 2.3 2 0 0 2 2 2 0 Probable zinc-binding domain DDE_3 PF13358.1 EIE86691.1 - 8e-09 35.3 1.2 2.1e-08 34.0 0.7 1.8 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE86691.1 - 5.4e-06 26.3 0.4 1.4e-05 25.0 0.2 1.7 1 0 0 1 1 1 1 Transposase HTH_Tnp_ISL3 PF13542.1 EIE86691.1 - 0.18 10.9 1.2 0.95 8.7 0.1 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 rve PF00665.21 EIE86692.1 - 1.9e-22 79.6 0.0 4.7e-22 78.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE86692.1 - 1.5e-15 57.1 0.1 2.9e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.12 EIE86692.1 - 8.5e-09 35.3 0.1 2.4e-08 33.9 0.1 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein Chromo PF00385.19 EIE86692.1 - 4.4e-08 32.6 0.1 1e-07 31.5 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.1 EIE86692.1 - 5.3e-05 23.6 0.0 0.00012 22.4 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.5 EIE86692.1 - 0.00044 19.5 1.6 0.0015 17.8 1.1 2.0 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Asp_protease PF09668.5 EIE86692.1 - 0.0082 15.7 0.0 0.019 14.5 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EIE86692.1 - 0.023 14.4 0.0 0.058 13.2 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease UBN2 PF14223.1 EIE86692.1 - 0.14 11.9 0.0 0.37 10.5 0.0 1.8 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Transposase_21 PF02992.9 EIE86693.1 - 3.7e-23 81.7 0.1 3.7e-23 81.7 0.1 1.7 2 0 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.1 EIE86693.1 - 3.8e-05 23.1 0.1 8.8e-05 21.9 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) DDE_3 PF13358.1 EIE86694.1 - 8.2e-13 48.3 0.0 1.2e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease RVT_1 PF00078.22 EIE86695.1 - 2.7e-13 49.7 0.0 4.5e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_Tnp_IS1595 PF12762.2 EIE86696.1 - 2.1e-22 79.5 0.5 3.5e-22 78.8 0.4 1.3 1 0 0 1 1 1 1 ISXO2-like transposase domain Transposase_21 PF02992.9 EIE86698.1 - 6.8e-22 77.6 0.0 1.5e-21 76.5 0.0 1.5 1 0 0 1 1 1 1 Transposase family tnp2 DUF1258 PF06869.7 EIE86698.1 - 0.0026 16.8 0.0 0.0041 16.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) DDE_3 PF13358.1 EIE86700.1 - 7.3e-25 87.4 0.0 9.3e-25 87.0 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE86700.1 - 0.00019 21.5 0.0 0.00036 20.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.12 EIE86703.1 - 7.1e-06 26.0 0.7 4.9e-05 23.3 0.2 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein UBN2_2 PF14227.1 EIE86703.1 - 0.0054 16.2 0.3 0.015 14.8 0.0 1.9 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EIE86703.1 - 0.0076 16.0 0.1 0.019 14.7 0.0 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Kinesin PF00225.18 EIE86707.1 - 8.1e-102 340.3 3.9 8.1e-102 340.3 2.7 1.6 2 0 0 2 2 2 1 Kinesin motor domain DUF724 PF05266.9 EIE86707.1 - 0.88 9.1 23.4 2.4 7.7 16.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Phage_GP20 PF06810.6 EIE86707.1 - 2.4 7.5 22.9 5.2 6.4 8.8 2.6 1 1 1 2 2 2 0 Phage minor structural protein GP20 TMF_DNA_bd PF12329.3 EIE86707.1 - 2.9 7.7 35.7 0.052 13.3 19.3 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Isochorismatase PF00857.15 EIE86708.1 - 2.6e-24 86.0 0.2 5e-24 85.1 0.1 1.5 1 1 0 1 1 1 1 Isochorismatase family ABC2_membrane PF01061.19 EIE86709.1 - 4.6e-85 284.0 61.6 9.5e-49 165.4 16.2 4.0 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.22 EIE86709.1 - 1.9e-34 118.8 0.0 7.6e-18 65.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EIE86709.1 - 2.5e-24 84.8 3.0 2.1e-18 65.8 0.0 3.8 4 0 0 4 4 2 2 CDR ABC transporter ABC_trans_N PF14510.1 EIE86709.1 - 1.2e-08 34.9 0.0 2.8e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_21 PF13304.1 EIE86709.1 - 3.4e-05 23.9 2.0 0.22 11.4 0.0 2.9 3 0 0 3 3 2 2 AAA domain DUF258 PF03193.11 EIE86709.1 - 9.1e-05 21.7 0.1 0.0049 16.0 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EIE86709.1 - 0.0004 19.8 0.3 0.0096 15.4 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.1 EIE86709.1 - 0.0004 19.8 0.0 0.0078 15.6 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 EIE86709.1 - 0.0007 19.7 0.0 0.11 12.6 0.0 3.1 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 EIE86709.1 - 0.015 14.9 0.6 0.31 10.6 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_33 PF13671.1 EIE86709.1 - 0.02 14.7 0.0 0.4 10.5 0.0 2.7 3 0 0 3 3 2 0 AAA domain cobW PF02492.14 EIE86709.1 - 0.041 13.3 0.0 0.093 12.1 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain SbcCD_C PF13558.1 EIE86709.1 - 0.046 13.6 0.0 0.25 11.2 0.0 2.2 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 EIE86709.1 - 0.055 13.7 1.0 0.27 11.5 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.1 EIE86709.1 - 0.058 14.2 0.1 0.63 10.8 0.0 2.7 3 0 0 3 3 2 0 AAA domain Zeta_toxin PF06414.7 EIE86709.1 - 0.064 12.3 0.1 0.64 9.0 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_28 PF13521.1 EIE86709.1 - 0.11 12.4 0.1 0.32 10.9 0.1 1.8 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 EIE86709.1 - 0.12 12.8 0.0 6.2 7.3 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein Taxilin PF09728.4 EIE86709.1 - 0.15 11.1 8.9 0.025 13.6 0.3 2.2 2 0 0 2 2 2 0 Myosin-like coiled-coil protein AAA_15 PF13175.1 EIE86709.1 - 0.38 9.7 3.7 5.2 6.0 0.1 3.1 3 0 0 3 3 3 0 AAA ATPase domain AAA_19 PF13245.1 EIE86709.1 - 0.38 10.5 0.7 3.6 7.3 0.2 2.3 2 0 0 2 2 2 0 Part of AAA domain AAA_23 PF13476.1 EIE86709.1 - 0.62 10.3 6.2 0.78 10.0 0.2 2.7 3 0 0 3 3 2 0 AAA domain AAA_16 PF13191.1 EIE86709.1 - 1.2 9.0 5.6 1 9.3 0.1 3.2 3 2 1 4 4 3 0 AAA ATPase domain ABC2_membrane_3 PF12698.2 EIE86709.1 - 2 7.3 71.1 0.006 15.6 19.6 4.1 3 2 0 3 3 3 0 ABC-2 family transporter protein VTC PF09359.5 EIE86710.1 - 1.5e-83 280.0 0.0 2.5e-83 279.3 0.0 1.4 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 EIE86710.1 - 1.1e-24 87.6 5.7 1.7e-11 44.4 0.1 3.3 1 1 1 2 2 2 2 SPX domain Sda PF08970.5 EIE86710.1 - 0.024 14.1 0.5 1.4 8.4 0.3 3.3 3 0 0 3 3 3 0 Sporulation inhibitor A Not3 PF04065.10 EIE86711.1 - 7.4e-94 313.3 25.1 7.4e-94 313.3 17.4 1.5 2 0 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 EIE86711.1 - 1.6e-45 154.2 11.7 4.9e-45 152.6 8.1 1.9 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Syntaxin PF00804.20 EIE86711.1 - 0.57 10.3 10.4 0.77 9.9 4.8 2.7 1 1 1 2 2 2 0 Syntaxin Syntaxin-6_N PF09177.6 EIE86711.1 - 0.81 10.1 10.7 61 4.1 5.4 3.5 2 1 1 3 3 3 0 Syntaxin 6, N-terminal B12D PF06522.6 EIE86712.1 - 1.2e-19 69.7 0.1 1.4e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit Voltage_CLC PF00654.15 EIE86712.1 - 0.14 11.1 0.0 0.15 11.0 0.0 1.0 1 0 0 1 1 1 0 Voltage gated chloride channel FKBP_C PF00254.23 EIE86713.1 - 1.7e-21 75.9 0.0 3.6e-21 74.9 0.0 1.6 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_11 PF13414.1 EIE86713.1 - 1e-15 57.1 7.1 4.9e-09 35.7 1.6 2.5 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 EIE86713.1 - 5.9e-14 50.9 5.7 1e-05 24.9 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EIE86713.1 - 2.8e-12 45.5 3.3 0.0004 20.0 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 EIE86713.1 - 3.6e-10 39.6 6.6 8.7e-07 28.7 0.2 2.5 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 EIE86713.1 - 6.1e-09 35.0 3.1 0.00033 20.2 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EIE86713.1 - 2.1e-06 27.1 0.1 0.059 13.1 0.0 2.9 2 1 0 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 EIE86713.1 - 0.00044 20.3 5.6 0.0069 16.5 0.8 2.4 1 1 2 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EIE86713.1 - 0.00086 19.9 0.2 0.55 10.9 0.0 2.7 2 1 1 3 3 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 EIE86713.1 - 0.00098 19.4 0.1 0.64 10.6 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 EIE86713.1 - 0.0012 18.8 0.0 0.0047 17.0 0.0 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.1 EIE86713.1 - 0.0016 18.7 0.0 0.0057 16.9 0.0 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 EIE86713.1 - 0.012 16.2 0.1 14 6.6 0.0 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat DUF357 PF04010.8 EIE86713.1 - 0.018 14.7 0.1 0.061 13.0 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF357) Fis1_TPR_C PF14853.1 EIE86713.1 - 0.082 12.7 3.0 18 5.2 0.0 3.3 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TcpE PF12648.2 EIE86714.1 - 0.11 12.6 0.8 0.12 12.5 0.5 1.1 1 0 0 1 1 1 0 TcpE family Tmemb_185A PF10269.4 EIE86715.1 - 6.8e-15 55.3 35.5 5e-07 29.5 4.9 3.2 1 1 2 3 3 3 3 Transmembrane Fragile-X-F protein CcmH PF03918.9 EIE86715.1 - 9.6 5.1 7.4 5.6 5.9 0.0 2.8 1 1 2 3 3 3 0 Cytochrome C biogenesis protein Cyto_heme_lyase PF01265.12 EIE86716.1 - 2.5e-39 135.4 8.2 6.8e-36 124.1 4.7 2.0 1 1 1 2 2 2 2 Cytochrome c/c1 heme lyase SeleniumBinding PF11524.3 EIE86716.1 - 0.04 14.0 0.0 0.068 13.3 0.0 1.3 1 0 0 1 1 1 0 Selenium binding protein LysM PF01476.15 EIE86717.1 - 1.3e-09 37.7 0.0 9.2e-06 25.4 0.0 2.3 2 0 0 2 2 2 2 LysM domain FAM220 PF15487.1 EIE86717.1 - 0.075 12.3 6.6 0.088 12.1 4.5 1.2 1 0 0 1 1 1 0 FAM220 family DUF2201_N PF13203.1 EIE86717.1 - 0.079 12.1 2.5 0.087 11.9 1.7 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain NARP1 PF12569.3 EIE86717.1 - 0.13 10.9 8.7 0.15 10.7 6.0 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 SRP-alpha_N PF04086.8 EIE86717.1 - 0.16 11.3 16.7 0.2 11.0 11.6 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF4228 PF14009.1 EIE86717.1 - 0.17 12.0 7.5 0.32 11.1 5.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4228) YtxH PF12732.2 EIE86717.1 - 0.25 11.7 8.5 0.54 10.6 5.9 1.6 1 0 0 1 1 1 0 YtxH-like protein DUF3807 PF12720.2 EIE86717.1 - 0.29 11.2 12.3 0.41 10.7 8.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Vfa1 PF08432.5 EIE86717.1 - 0.38 10.7 14.5 0.52 10.3 10.0 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 TATR PF03430.8 EIE86717.1 - 0.49 8.9 7.5 0.52 8.8 5.2 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator DUF913 PF06025.7 EIE86717.1 - 1.6 7.4 6.5 1.8 7.2 4.0 1.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Macoilin PF09726.4 EIE86717.1 - 1.7 6.8 11.3 1.9 6.6 7.8 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF2413 PF10310.4 EIE86717.1 - 2.6 6.7 15.5 3.2 6.4 10.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DUF2215 PF10225.4 EIE86717.1 - 3.2 7.1 4.3 4.4 6.6 3.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) MDFI PF15316.1 EIE86717.1 - 4.2 7.3 9.6 7.7 6.4 6.7 1.4 1 0 0 1 1 1 0 MyoD family inhibitor NPR3 PF03666.8 EIE86717.1 - 6 5.2 11.6 7.4 4.9 8.0 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SNARE_assoc PF09335.6 EIE86718.1 - 6.1e-18 65.1 8.5 6.1e-18 65.1 5.9 1.9 2 0 0 2 2 2 1 SNARE associated Golgi protein Caveolin PF01146.12 EIE86718.1 - 0.31 10.6 2.3 0.86 9.1 1.6 1.7 1 0 0 1 1 1 0 Caveolin PetN PF03742.9 EIE86718.1 - 2.1 7.9 5.7 0.82 9.2 0.7 2.6 2 0 0 2 2 2 0 PetN SPRY PF00622.23 EIE86719.1 - 5.3e-27 94.3 0.6 8.5e-27 93.7 0.4 1.3 1 0 0 1 1 1 1 SPRY domain CLTH PF10607.4 EIE86719.1 - 2e-10 40.5 0.0 3.2e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 EIE86719.1 - 2.9e-05 23.6 0.1 6.5e-05 22.5 0.1 1.6 1 0 0 1 1 1 1 LisH Pyr_excise PF03013.9 EIE86719.1 - 0.016 14.9 0.3 0.064 13.0 0.0 2.1 2 0 0 2 2 2 0 Pyrimidine dimer DNA glycosylase FUSC_2 PF13515.1 EIE86720.1 - 1.3e-15 57.4 13.7 1.3e-15 57.4 9.5 2.0 2 0 0 2 2 2 1 Fusaric acid resistance protein-like DUF2421 PF10334.4 EIE86720.1 - 1.8e-10 40.8 0.0 3.2e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2421) ALMT PF11744.3 EIE86720.1 - 3.3e-08 32.5 1.5 3.3e-08 32.5 1.1 2.0 2 1 1 3 3 3 1 Aluminium activated malate transporter FUSC PF04632.7 EIE86720.1 - 2.9e-06 26.0 4.7 5.3e-06 25.1 3.2 1.4 1 0 0 1 1 1 1 Fusaric acid resistance protein family DUF2422 PF10337.4 EIE86720.1 - 1.1e-05 24.5 0.6 2.3e-05 23.4 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2422) AMP-binding PF00501.23 EIE86721.1 - 2.7e-68 230.2 0.1 8.2e-65 218.8 0.1 2.8 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 EIE86721.1 - 1.1e-11 45.5 0.1 8.3e-11 42.6 0.0 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.23 EIE86722.1 - 6.5e-84 281.7 0.0 6.8e-82 275.0 0.0 2.1 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 EIE86722.1 - 2.2e-13 50.9 0.1 4.7e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Phtf-FEM1B_bdg PF12129.3 EIE86722.1 - 0.084 12.2 0.2 0.2 10.9 0.1 1.6 1 0 0 1 1 1 0 Male germ-cell putative homeodomain transcription factor MFS_1 PF07690.11 EIE86723.1 - 4.7e-51 173.5 47.9 1e-49 169.1 33.0 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EIE86723.1 - 2e-16 59.3 18.8 2.5e-16 59.0 13.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EIE86723.1 - 7.1e-14 51.2 14.4 7.1e-14 51.2 10.0 2.6 1 1 0 2 2 2 1 Sugar (and other) transporter OAD_gamma PF04277.8 EIE86723.1 - 0.023 15.0 0.2 13 6.2 0.0 3.2 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain DUF4181 PF13789.1 EIE86723.1 - 0.049 13.5 0.3 0.049 13.5 0.2 3.2 2 1 0 3 3 3 0 Domain of unknown function (DUF4181) Nop52 PF05997.7 EIE86724.1 - 1.5e-41 142.2 0.0 1.7e-41 142.0 0.0 1.0 1 0 0 1 1 1 1 Nucleolar protein,Nop52 Pectate_lyase_2 PF06917.7 EIE86724.1 - 0.045 11.9 0.0 0.057 11.6 0.0 1.2 1 0 0 1 1 1 0 Periplasmic pectate lyase L31 PF09784.4 EIE86725.1 - 1e-37 128.3 0.1 1.1e-37 128.1 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 DUF3450 PF11932.3 EIE86726.1 - 0.066 12.4 7.1 0.12 11.6 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) YoaP PF14268.1 EIE86726.1 - 0.34 10.1 2.2 3 7.1 0.7 2.5 2 0 0 2 2 2 0 YoaP-like Folate_carrier PF01770.13 EIE86726.1 - 1.7 7.0 3.7 1.9 6.9 2.1 1.3 1 1 0 1 1 1 0 Reduced folate carrier BAF1_ABF1 PF04684.8 EIE86726.1 - 1.9 7.2 22.0 2.7 6.7 15.2 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor F-box-like PF12937.2 EIE86728.1 - 0.00055 19.6 1.1 0.00055 19.6 0.8 2.1 1 1 1 2 2 2 1 F-box-like F-box PF00646.28 EIE86728.1 - 0.0086 15.7 0.5 0.021 14.4 0.4 1.7 1 0 0 1 1 1 1 F-box domain Ras PF00071.17 EIE86730.1 - 6e-35 120.0 0.6 3.1e-34 117.7 0.4 1.8 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EIE86730.1 - 1.3e-05 25.7 0.0 4.1e-05 24.0 0.0 1.9 1 1 0 1 1 1 1 Miro-like protein AAA_24 PF13479.1 EIE86730.1 - 0.0058 16.2 0.0 0.0096 15.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain Arf PF00025.16 EIE86730.1 - 0.014 14.6 0.2 0.11 11.7 0.1 2.0 1 1 0 1 1 1 0 ADP-ribosylation factor family AAA_22 PF13401.1 EIE86730.1 - 0.015 15.4 0.2 0.26 11.4 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EIE86730.1 - 0.029 13.8 0.0 0.033 13.6 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain DUF258 PF03193.11 EIE86730.1 - 0.031 13.4 0.0 0.058 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ABC_tran PF00005.22 EIE86730.1 - 0.086 13.1 0.4 0.2 11.9 0.3 2.0 1 1 0 1 1 1 0 ABC transporter AF0941-like PF14591.1 EIE86730.1 - 0.1 12.6 0.1 0.4 10.7 0.0 1.8 2 0 0 2 2 2 0 AF0941-like Ribosomal_L14 PF00238.14 EIE86731.1 - 1.4e-34 118.4 0.0 1.6e-34 118.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e OTCace_N PF02729.16 EIE86732.1 - 3.6e-46 156.3 0.1 5.9e-46 155.6 0.1 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 EIE86732.1 - 6.3e-44 149.6 0.1 1.2e-43 148.6 0.0 1.5 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OCD_Mu_crystall PF02423.10 EIE86732.1 - 0.0089 14.8 0.7 0.018 13.8 0.5 1.4 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Peptidase_M28 PF04389.12 EIE86733.1 - 1.5e-30 106.2 0.2 3.3e-30 105.1 0.1 1.6 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EIE86733.1 - 0.00017 21.1 0.0 0.00034 20.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 PGM_PMM_I PF02878.11 EIE86734.1 - 6.6e-17 61.2 0.2 2.8e-08 33.3 0.0 3.8 2 1 2 4 4 4 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 EIE86734.1 - 1.2e-11 44.8 1.2 1.4e-10 41.4 0.3 2.8 2 2 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 EIE86734.1 - 0.026 14.5 0.1 0.056 13.4 0.1 1.5 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III Abhydrolase_6 PF12697.2 EIE86735.1 - 4.1e-18 66.0 0.0 5e-18 65.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIE86735.1 - 1.6e-07 31.1 0.0 2.4e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIE86735.1 - 5.9e-07 29.2 0.0 8.5e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF915 PF06028.6 EIE86735.1 - 0.049 12.7 0.0 0.081 12.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Pex14_N PF04695.8 EIE86737.1 - 4.5e-23 81.7 0.0 4.5e-23 81.7 0.0 1.7 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region SSP160 PF06933.6 EIE86737.1 - 0.43 8.4 3.7 0.5 8.2 2.6 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3439 PF11921.3 EIE86737.1 - 0.62 9.8 9.2 0.97 9.2 6.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) PBP PF01161.15 EIE86738.1 - 9.8e-22 77.3 0.1 1.6e-21 76.6 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein DUF1699 PF08004.6 EIE86739.1 - 0.061 12.8 1.8 0.16 11.5 0.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1699) Macoilin PF09726.4 EIE86739.1 - 6.8 4.8 28.2 24 3.0 19.6 1.8 1 1 0 1 1 1 0 Transmembrane protein SNARE PF05739.14 EIE86741.1 - 0.00047 19.7 0.5 0.00063 19.3 0.3 1.2 1 0 0 1 1 1 1 SNARE domain Sec20 PF03908.8 EIE86741.1 - 0.0053 16.4 0.3 0.021 14.5 0.2 1.8 2 0 0 2 2 2 1 Sec20 CASP_C PF08172.7 EIE86741.1 - 0.068 12.1 0.1 0.086 11.8 0.1 1.1 1 0 0 1 1 1 0 CASP C terminal V-ATPase_C PF03223.10 EIE86741.1 - 0.095 11.5 0.0 0.11 11.3 0.0 1.0 1 0 0 1 1 1 0 V-ATPase subunit C LRR_6 PF13516.1 EIE86742.1 - 1.2e-10 40.3 15.2 0.15 12.2 0.0 7.7 8 0 0 8 8 8 4 Leucine Rich repeat F-box-like PF12937.2 EIE86742.1 - 1.4e-08 34.3 4.1 1.7e-08 34.0 0.0 3.1 3 1 0 3 3 3 1 F-box-like F-box PF00646.28 EIE86742.1 - 7.2e-06 25.5 0.5 7.7e-05 22.2 0.1 3.1 2 0 0 2 2 2 1 F-box domain LRR_4 PF12799.2 EIE86742.1 - 1.1e-05 24.9 19.5 0.0085 15.7 1.4 5.9 4 1 4 8 8 8 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EIE86742.1 - 0.0065 16.2 16.1 0.76 9.5 0.1 5.4 3 1 3 6 6 6 4 Leucine rich repeat LRR_7 PF13504.1 EIE86742.1 - 0.0068 16.4 21.2 18 6.0 0.1 7.8 6 2 0 6 6 6 0 Leucine rich repeat Ste50p-SAM PF09235.5 EIE86742.1 - 0.059 13.4 1.7 12 6.0 0.0 3.1 3 1 0 3 3 3 0 Ste50p, sterile alpha motif LRR_1 PF00560.28 EIE86742.1 - 0.06 13.4 21.1 19 5.7 0.1 7.7 7 1 0 7 7 7 0 Leucine Rich Repeat LRR_9 PF14580.1 EIE86742.1 - 0.06 12.8 0.3 8.1 5.9 0.0 2.6 2 0 0 2 2 2 0 Leucine-rich repeat Mito_carr PF00153.22 EIE86744.1 - 6.4e-43 144.3 1.7 1.2e-21 76.1 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein Ribosomal_L2_C PF03947.13 EIE86745.1 - 3.4e-42 143.3 2.3 3.4e-42 143.3 1.6 1.5 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EIE86745.1 - 1.8e-15 56.6 0.1 4.4e-15 55.4 0.1 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain CYSTM PF12734.2 EIE86746.1 - 0.0012 18.8 61.0 0.0093 16.0 28.0 4.4 1 1 1 2 2 2 1 Cysteine-rich TM module stress tolerance Peptidase_M24 PF00557.19 EIE86747.1 - 3.3e-46 157.5 0.2 3.7e-46 157.3 0.1 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 ATP-cone PF03477.11 EIE86747.1 - 0.086 13.2 0.1 0.37 11.2 0.1 1.9 2 0 0 2 2 2 0 ATP cone domain DUF3759 PF12585.3 EIE86748.1 - 6.2e-28 96.5 10.7 7.6e-28 96.2 7.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) Citrate_synt PF00285.16 EIE86748.1 - 0.011 14.4 1.0 0.012 14.3 0.7 1.2 1 0 0 1 1 1 0 Citrate synthase AIPR PF10592.4 EIE86748.1 - 0.019 14.2 1.5 0.024 13.9 1.1 1.0 1 0 0 1 1 1 0 AIPR protein DUF2309 PF10070.4 EIE86748.1 - 0.05 11.7 2.4 0.054 11.5 1.7 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2309) PepSY_2 PF13670.1 EIE86748.1 - 0.23 11.3 1.9 0.42 10.5 0.5 2.0 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain DPRP PF04244.8 EIE86748.1 - 0.27 10.7 2.5 0.38 10.2 1.7 1.2 1 0 0 1 1 1 0 Deoxyribodipyrimidine photo-lyase-related protein YchF-GTPase_C PF06071.8 EIE86749.1 - 2.7e-39 132.8 0.1 5.2e-39 131.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 EIE86749.1 - 4.5e-11 42.7 0.0 1.6e-10 40.9 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EIE86749.1 - 0.0095 15.2 0.0 0.035 13.3 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B TGS PF02824.16 EIE86749.1 - 0.041 13.7 0.0 0.12 12.2 0.0 1.8 1 0 0 1 1 1 0 TGS domain Pkinase PF00069.20 EIE86750.1 - 5e-40 137.2 0.1 6.9e-40 136.8 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE86750.1 - 9.3e-30 103.5 0.1 1.2e-29 103.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE86750.1 - 0.031 13.2 0.0 0.057 12.3 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Seadorna_VP7 PF07387.6 EIE86750.1 - 0.056 12.2 0.0 0.087 11.6 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Ribosomal_S19e PF01090.14 EIE86751.1 - 3.1e-61 204.8 0.2 3.5e-61 204.7 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e O-FucT PF10250.4 EIE86752.1 - 2.5e-15 56.4 0.0 2.7e-14 53.0 0.0 2.3 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase DUF4098 PF13345.1 EIE86752.1 - 1.3e-05 25.0 8.3 0.032 14.1 0.8 3.5 2 1 1 3 3 3 2 Domain of unknown function (DUF4098) RLAN PF14401.1 EIE86752.1 - 0.068 12.6 0.0 0.34 10.3 0.0 2.1 2 1 0 2 2 2 0 RimK-like ATPgrasp N-terminal domain LON PF02190.11 EIE86753.1 - 9.7e-21 74.3 0.0 1.2e-19 70.8 0.0 2.1 1 1 0 1 1 1 1 ATP-dependent protease La (LON) domain zf-RING_2 PF13639.1 EIE86753.1 - 1.9e-08 34.0 16.5 3.7e-08 33.0 10.9 1.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EIE86753.1 - 3.3e-08 33.4 15.1 5.9e-08 32.6 10.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EIE86753.1 - 5.8e-08 32.2 10.5 1.1e-07 31.4 7.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIE86753.1 - 4.1e-07 29.5 15.5 7.3e-07 28.7 10.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIE86753.1 - 8e-06 25.4 14.9 1.4e-05 24.7 10.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EIE86753.1 - 0.00017 21.3 13.8 0.00032 20.5 9.5 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EIE86753.1 - 0.04 13.6 8.9 0.1 12.3 6.1 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-rbx1 PF12678.2 EIE86753.1 - 0.12 12.5 13.1 0.27 11.3 8.1 2.4 2 1 0 2 2 2 0 RING-H2 zinc finger zf-RING_4 PF14570.1 EIE86753.1 - 0.18 11.3 9.9 0.36 10.4 6.9 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.1 EIE86753.1 - 0.28 10.7 12.4 0.69 9.5 8.6 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_6 PF14835.1 EIE86753.1 - 1.1 9.0 5.7 2.1 8.1 3.9 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Gti1_Pac2 PF09729.4 EIE86754.1 - 3.9e-55 186.2 5.3 8.6e-54 181.8 0.7 3.0 2 1 0 2 2 2 1 Gti1/Pac2 family PAPS_reduct PF01507.14 EIE86755.1 - 2.1e-44 151.4 0.0 2.7e-44 151.0 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family RPAP3_C PF13877.1 EIE86755.1 - 0.3 11.0 2.2 3.1 7.8 0.0 3.0 4 0 0 4 4 4 0 Potential Monad-binding region of RPAP3 UreE_N PF02814.10 EIE86756.1 - 0.078 12.4 0.0 0.2 11.1 0.0 1.6 1 0 0 1 1 1 0 UreE urease accessory protein, N-terminal domain Membralin PF09746.4 EIE86756.1 - 2.6 7.0 5.5 3.5 6.5 3.8 1.2 1 0 0 1 1 1 0 Tumour-associated protein hDGE_amylase PF14701.1 EIE86756.1 - 3.4 6.4 16.0 3.8 6.2 10.6 1.4 1 1 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme PLRV_ORF5 PF01690.12 EIE86756.1 - 4.4 6.3 13.4 5.4 6.0 9.3 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein UcrQ PF02939.11 EIE86757.1 - 1e-28 98.9 0.3 1.3e-28 98.6 0.2 1.0 1 0 0 1 1 1 1 UcrQ family CHCH PF06747.8 EIE86758.1 - 0.0026 17.6 0.3 0.0037 17.1 0.2 1.2 1 0 0 1 1 1 1 CHCH domain DUF1903 PF08991.5 EIE86758.1 - 0.0039 17.3 0.2 0.0049 16.9 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) DUF1722 PF08349.6 EIE86758.1 - 0.089 12.6 0.0 0.089 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1722) p450 PF00067.17 EIE86759.1 - 4.5e-70 236.4 0.2 5.3e-70 236.2 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 NTNH_C PF08470.5 EIE86759.1 - 0.062 12.9 0.1 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Nontoxic nonhaemagglutinin C-terminal DXP_synthase_N PF13292.1 EIE86759.1 - 0.095 11.6 0.0 0.19 10.6 0.0 1.5 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase HTH_32 PF13565.1 EIE86760.1 - 0.0015 19.2 0.0 0.0038 17.9 0.0 1.6 1 1 1 2 2 2 1 Homeodomain-like domain Chromo PF00385.19 EIE86762.1 - 2.4e-11 43.1 0.4 5.6e-11 41.9 0.3 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DDE_3 PF13358.1 EIE86763.1 - 1e-17 64.2 0.0 2.7e-17 62.8 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE86763.1 - 1e-08 35.1 0.9 2.7e-08 33.7 0.5 1.9 1 1 0 1 1 1 1 Transposase Rep_2 PF01719.12 EIE86764.1 - 0.013 14.9 1.9 0.022 14.2 1.3 1.3 1 0 0 1 1 1 0 Plasmid replication protein REGB_T4 PF10715.4 EIE86764.1 - 0.073 13.1 0.1 0.16 12.0 0.0 1.6 1 1 0 1 1 1 0 Endoribonuclease RegB T4-bacteriophage encoded DUF4304 PF14137.1 EIE86764.1 - 0.17 12.0 1.6 0.23 11.5 0.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4304) RVT_1 PF00078.22 EIE86767.1 - 0.0009 18.6 0.0 0.00092 18.6 0.0 1.2 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE86768.1 - 1.6e-05 24.4 0.4 1.6e-05 24.4 0.3 2.1 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain NADHdh PF00146.16 EIE86769.1 - 0.012 14.7 0.1 0.02 13.9 0.1 1.3 1 0 0 1 1 1 0 NADH dehydrogenase DUF2235 PF09994.4 EIE86770.1 - 2.5e-18 66.4 0.1 3e-18 66.1 0.1 1.0 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF2974 PF11187.3 EIE86770.1 - 0.043 13.1 0.0 0.064 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Homoserine_dh PF00742.14 EIE86771.1 - 1.6e-49 168.0 0.0 4e-49 166.6 0.0 1.7 2 0 0 2 2 2 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 EIE86771.1 - 5.8e-15 55.7 0.0 9.5e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 EIE86771.1 - 0.00034 20.8 0.1 0.0012 19.1 0.0 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 EIE86771.1 - 0.0073 16.2 0.0 0.018 14.9 0.0 1.8 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus F420_oxidored PF03807.12 EIE86771.1 - 0.014 15.7 0.3 0.044 14.2 0.2 1.9 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF835 PF05763.7 EIE86771.1 - 0.071 12.6 0.0 0.19 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF835) zf-CCHC PF00098.18 EIE86773.1 - 0.023 14.5 18.7 0.027 14.3 0.9 3.2 3 0 0 3 3 3 0 Zinc knuckle DnaJ_CXXCXGXG PF00684.14 EIE86773.1 - 0.54 10.3 7.5 6.3 6.9 0.1 2.6 2 0 0 2 2 2 0 DnaJ central domain RVT_1 PF00078.22 EIE86774.1 - 4.3e-36 124.2 0.1 8.1e-36 123.3 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.1 EIE86774.1 - 0.002 18.4 0.2 0.0062 16.8 0.1 1.9 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase DDE_3 PF13358.1 EIE86775.1 - 2.9e-15 56.2 0.1 5.6e-15 55.3 0.1 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE86775.1 - 6.3e-11 42.1 0.7 1.3e-10 41.1 0.5 1.5 1 0 0 1 1 1 1 Transposase Lge1 PF11488.3 EIE86775.1 - 0.11 12.6 0.0 2.8 8.1 0.0 2.3 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 SDH_alpha PF03313.10 EIE86776.1 - 3.5e-102 341.2 0.2 4.5e-102 340.8 0.1 1.1 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.10 EIE86776.1 - 3.5e-55 186.3 0.0 7.1e-55 185.3 0.0 1.5 1 0 0 1 1 1 1 Serine dehydratase beta chain MmgE_PrpD PF03972.9 EIE86776.1 - 0.0078 14.4 1.1 0.012 13.8 0.7 1.2 1 0 0 1 1 1 1 MmgE/PrpD family RNR_N PF08343.5 EIE86776.1 - 0.024 14.4 0.0 0.057 13.2 0.0 1.6 1 0 0 1 1 1 0 Ribonucleotide reductase N-terminal Polysacc_deac_1 PF01522.16 EIE86777.1 - 1.9e-08 34.0 0.0 4.2e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide deacetylase Cu-binding_MopE PF11617.3 EIE86777.1 - 3.1 7.6 7.5 0.69 9.7 2.4 2.1 2 0 0 2 2 2 0 Protein metal binding site Sec7 PF01369.15 EIE86778.1 - 2.7e-58 196.7 0.9 5.3e-58 195.8 0.6 1.5 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 EIE86778.1 - 1.5e-16 60.2 2.5 1.3e-10 40.9 0.5 3.5 3 0 0 3 3 3 2 Guanine nucleotide exchange factor in Golgi transport N-terminal CobU PF02283.11 EIE86781.1 - 0.039 13.3 6.0 0.47 9.8 0.4 3.2 2 1 1 3 3 3 0 Cobinamide kinase / cobinamide phosphate guanyltransferase KH_1 PF00013.24 EIE86782.1 - 2.2e-24 84.8 0.2 2.4e-09 36.6 0.0 6.8 7 0 0 7 7 7 5 KH domain KH_3 PF13014.1 EIE86782.1 - 7.3e-19 66.9 0.2 2.1e-07 30.4 0.0 5.8 5 0 0 5 5 5 4 KH domain ArsA_ATPase PF02374.10 EIE86783.1 - 1.8e-115 385.1 1.3 2.1e-115 384.9 0.9 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 EIE86783.1 - 1.4e-14 53.9 0.0 2.2e-14 53.3 0.0 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EIE86783.1 - 4.8e-08 33.0 0.0 1.5e-07 31.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain Fer4_NifH PF00142.13 EIE86783.1 - 0.00016 20.9 0.0 0.00034 19.8 0.0 1.6 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_25 PF13481.1 EIE86783.1 - 0.00016 21.1 0.0 0.00057 19.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain SRP54 PF00448.17 EIE86783.1 - 0.0002 20.8 1.0 0.0014 18.1 0.0 2.4 2 1 1 3 3 3 1 SRP54-type protein, GTPase domain YhjQ PF06564.7 EIE86783.1 - 0.0029 17.0 0.0 0.0047 16.3 0.0 1.3 1 0 0 1 1 1 1 YhjQ protein MipZ PF09140.6 EIE86783.1 - 0.046 12.8 0.1 0.081 11.9 0.1 1.6 1 1 0 1 1 1 0 ATPase MipZ AMP-binding_C_2 PF14535.1 EIE86783.1 - 0.079 13.0 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain DnaJ PF00226.26 EIE86784.1 - 3.5e-28 97.1 2.6 5.4e-28 96.5 1.8 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EIE86784.1 - 1.6e-14 53.6 19.2 2.5e-14 53.0 13.3 1.3 1 0 0 1 1 1 1 DnaJ central domain CTDII PF01556.13 EIE86784.1 - 2.3e-10 40.1 1.0 2e-06 27.5 0.0 2.8 3 0 0 3 3 3 2 DnaJ C terminal domain HypA PF01155.14 EIE86784.1 - 0.07 12.8 10.5 0.49 10.1 1.8 2.2 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family DUF2614 PF11023.3 EIE86784.1 - 0.61 9.8 3.9 5.8 6.7 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2614) SPX PF03105.14 EIE86785.1 - 5.8e-39 134.5 1.6 9.9e-39 133.7 1.1 1.4 1 0 0 1 1 1 1 SPX domain Na_sulph_symp PF00939.14 EIE86785.1 - 3.3e-29 102.1 39.3 4.5e-29 101.6 27.2 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 EIE86785.1 - 1.2e-12 47.0 44.0 1.9e-12 46.4 15.4 2.5 1 1 1 2 2 2 2 Citrate transporter Ribosomal_S16 PF00886.14 EIE86786.1 - 2.3e-26 91.2 0.1 3.2e-26 90.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S16 PCI PF01399.22 EIE86787.1 - 7.1e-19 68.0 0.9 1.7e-18 66.8 0.1 2.0 2 0 0 2 2 2 1 PCI domain FTA4 PF13093.1 EIE86787.1 - 3.4 7.0 10.2 0.7 9.2 0.9 2.2 2 0 0 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Pkinase PF00069.20 EIE86788.1 - 3.2e-18 65.8 0.1 1.4e-17 63.7 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE86788.1 - 3.1e-17 62.5 0.1 3e-16 59.2 0.0 2.2 2 1 1 3 3 3 1 Protein tyrosine kinase DUF775 PF05603.7 EIE86788.1 - 2.2 7.7 5.5 8.2 5.8 1.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF775) AMPKBI PF04739.10 EIE86788.1 - 8.3 6.3 10.3 22 4.9 3.4 2.5 2 1 0 2 2 2 0 5'-AMP-activated protein kinase beta subunit, interation domain Peroxidase_2 PF01328.12 EIE86789.1 - 5e-14 51.7 0.0 9.2e-14 50.8 0.0 1.3 1 1 0 1 1 1 1 Peroxidase, family 2 PDZ_1 PF12812.2 EIE86790.1 - 1.8e-40 136.7 0.0 3.3e-28 97.3 0.0 2.6 2 0 0 2 2 2 2 PDZ-like domain PDZ_2 PF13180.1 EIE86790.1 - 8.4e-14 51.2 2.3 2.6e-05 24.0 0.0 3.9 4 0 0 4 4 4 3 PDZ domain Trypsin_2 PF13365.1 EIE86790.1 - 2e-10 40.7 0.1 9e-10 38.5 0.0 2.2 2 0 0 2 2 2 1 Trypsin-like peptidase domain PDZ PF00595.19 EIE86790.1 - 2.1e-07 30.9 0.0 0.00044 20.3 0.0 3.4 3 1 0 3 3 3 2 PDZ domain (Also known as DHR or GLGF) Tricorn_PDZ PF14685.1 EIE86790.1 - 0.0088 15.8 0.3 0.12 12.1 0.0 2.9 3 0 0 3 3 3 1 Tricorn protease PDZ domain Peptidase_S7 PF00949.16 EIE86790.1 - 0.029 13.7 0.2 0.068 12.5 0.2 1.5 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease DUF31 PF01732.11 EIE86790.1 - 0.039 13.2 0.4 0.067 12.5 0.2 1.3 1 0 0 1 1 1 0 Putative peptidase (DUF31) Cyt-b5 PF00173.23 EIE86791.1 - 1e-23 82.8 0.2 1e-23 82.8 0.1 1.7 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 EIE86791.1 - 6.4e-07 29.7 22.6 6.4e-07 29.7 15.6 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily HLH PF00010.21 EIE86792.1 - 4.4e-13 48.7 1.7 1e-12 47.5 1.2 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Peptidase_S64 PF08192.6 EIE86792.1 - 0.065 11.5 12.3 0.085 11.1 8.5 1.1 1 0 0 1 1 1 0 Peptidase family S64 EF1_GNE PF00736.14 EIE86793.1 - 3.7e-32 109.8 1.6 7.3e-32 108.9 1.1 1.5 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 EIE86793.1 - 1.3e-13 50.7 4.4 1.3e-13 50.7 3.0 2.4 3 0 0 3 3 3 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.1 EIE86793.1 - 0.00097 19.5 0.0 0.0022 18.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EIE86793.1 - 0.007 16.3 0.2 0.026 14.5 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain DUF2777 PF10949.3 EIE86793.1 - 0.33 10.6 3.4 0.97 9.0 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2777) KCl_Cotrans_1 PF03522.10 EIE86793.1 - 3.3 7.2 5.2 0.59 9.6 0.2 2.2 2 0 0 2 2 2 0 K-Cl Co-transporter type 1 (KCC1) Eapp_C PF10238.4 EIE86794.1 - 0.13 12.1 4.7 0.67 9.8 0.6 2.4 1 1 1 2 2 2 0 E2F-associated phosphoprotein Terminase_GpA PF05876.7 EIE86795.1 - 0.00048 18.6 0.2 0.00052 18.5 0.1 1.0 1 0 0 1 1 1 1 Phage terminase large subunit (GpA) Elf1 PF05129.8 EIE86795.1 - 0.0013 18.3 0.5 0.002 17.7 0.3 1.3 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like TFIIS_C PF01096.13 EIE86795.1 - 0.0032 17.0 2.4 0.9 9.2 0.3 2.2 2 0 0 2 2 2 2 Transcription factor S-II (TFIIS) Plectin PF00681.15 EIE86795.1 - 0.0046 16.4 0.0 0.0075 15.7 0.0 1.3 1 0 0 1 1 1 1 Plectin repeat DUF3716 PF12511.3 EIE86795.1 - 0.0068 15.9 0.9 0.011 15.3 0.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Zn_Tnp_IS1595 PF12760.2 EIE86795.1 - 0.0089 15.8 3.0 0.018 14.8 2.1 1.5 1 1 0 1 1 1 1 Transposase zinc-ribbon domain DUF2387 PF09526.5 EIE86795.1 - 0.011 15.6 2.4 0.72 9.8 1.6 2.1 1 1 0 1 1 1 0 Probable metal-binding protein (DUF2387) Rdx PF10262.4 EIE86795.1 - 0.014 15.4 0.4 0.094 12.7 0.0 2.0 2 0 0 2 2 2 0 Rdx family DUF2296 PF10058.4 EIE86795.1 - 0.019 14.6 0.8 1.6 8.5 0.1 2.3 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) Pput2613-deam PF14427.1 EIE86795.1 - 0.032 13.8 0.5 0.088 12.4 0.0 1.8 1 1 1 2 2 2 0 Pput_2613-like deaminase zf-Mss51 PF13824.1 EIE86795.1 - 0.035 13.9 0.3 0.05 13.4 0.2 1.3 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zinc_ribbon_2 PF13240.1 EIE86795.1 - 0.046 13.2 3.1 0.9 9.1 0.5 2.5 2 0 0 2 2 2 0 zinc-ribbon domain CpXC PF14353.1 EIE86795.1 - 0.065 13.1 1.2 0.1 12.5 0.9 1.4 1 0 0 1 1 1 0 CpXC protein DUF3797 PF12677.2 EIE86795.1 - 0.078 12.6 1.0 0.39 10.3 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3797) Ribosomal_L44 PF00935.14 EIE86795.1 - 0.21 11.6 3.7 3.6 7.6 0.2 2.1 1 1 1 2 2 2 0 Ribosomal protein L44 Mu-like_Com PF10122.4 EIE86795.1 - 0.25 10.4 2.4 2.2 7.4 0.2 2.2 1 1 1 2 2 2 0 Mu-like prophage protein Com HypA PF01155.14 EIE86795.1 - 0.27 10.9 2.5 1.2 8.8 0.1 2.0 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Zn_Tnp_IS1 PF03811.8 EIE86795.1 - 0.29 10.6 3.4 9.3 5.8 0.2 2.3 2 0 0 2 2 2 0 InsA N-terminal domain zf-LITAF-like PF10601.4 EIE86795.1 - 0.3 10.9 2.6 4.8 7.1 0.2 2.1 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain zf-RanBP PF00641.13 EIE86795.1 - 0.54 9.4 6.8 3 7.0 0.2 2.3 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others C1_4 PF07975.7 EIE86795.1 - 1.1 9.3 5.7 2.3 8.3 0.5 2.3 1 1 1 2 2 2 0 TFIIH C1-like domain tRNA-synt_1c PF00749.16 EIE86796.1 - 1.5e-104 349.0 0.0 2.5e-104 348.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.10 EIE86796.1 - 1.6e-48 164.3 0.4 2.6e-48 163.6 0.3 1.3 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.13 EIE86796.1 - 7.1e-38 129.9 0.2 2.6e-37 128.1 0.1 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.10 EIE86796.1 - 3.8e-16 59.5 9.3 3.8e-16 59.5 6.5 1.9 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Kelch_4 PF13418.1 EIE86797.1 - 3.9e-21 74.5 11.6 1.8e-06 27.6 0.1 5.1 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.1 EIE86797.1 - 2.6e-17 62.1 14.8 5.5e-05 23.1 0.1 5.8 3 2 2 5 5 5 4 Kelch motif Kelch_3 PF13415.1 EIE86797.1 - 2.2e-14 53.1 10.0 0.00062 19.8 0.0 5.7 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.10 EIE86797.1 - 2.5e-12 46.0 7.3 0.00011 21.7 0.0 6.5 5 1 0 5 5 5 3 Kelch motif Kelch_5 PF13854.1 EIE86797.1 - 2.6e-12 46.3 5.1 1.6e-05 24.7 0.0 4.7 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 EIE86797.1 - 9e-11 41.1 7.0 0.00066 19.1 0.1 4.9 4 0 0 4 4 4 3 Kelch motif Ni_hydr_CYTB PF01292.15 EIE86797.1 - 0.022 14.1 1.4 0.041 13.2 1.0 1.4 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 SKG6 PF08693.5 EIE86797.1 - 0.036 13.3 1.8 0.071 12.4 1.2 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain ASC PF00858.19 EIE86797.1 - 0.065 11.8 0.3 1.5 7.3 0.0 2.3 2 0 0 2 2 2 0 Amiloride-sensitive sodium channel VSP PF03302.8 EIE86797.1 - 0.27 9.8 4.0 0.064 11.8 0.6 1.4 2 0 0 2 2 2 0 Giardia variant-specific surface protein DUF4131 PF13567.1 EIE86797.1 - 1.3 8.4 5.4 0.22 10.8 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Kelch_6 PF13964.1 EIE86798.1 - 7.5e-19 67.0 10.5 2.3e-05 24.3 0.1 4.9 2 2 2 4 4 4 4 Kelch motif Kelch_3 PF13415.1 EIE86798.1 - 5.8e-18 64.5 5.3 7.4e-06 25.9 0.0 4.7 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_4 PF13418.1 EIE86798.1 - 1.5e-17 63.1 9.5 1.1e-05 25.0 0.1 5.6 5 1 0 5 5 5 4 Galactose oxidase, central domain Kelch_1 PF01344.20 EIE86798.1 - 5.3e-15 54.6 4.6 0.00058 19.3 0.0 4.6 4 0 0 4 4 4 3 Kelch motif Kelch_5 PF13854.1 EIE86798.1 - 5.2e-11 42.2 4.8 0.0076 16.1 0.0 4.7 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.10 EIE86798.1 - 2.3e-10 39.8 6.5 0.015 15.0 0.0 6.0 5 1 0 5 5 5 2 Kelch motif YqhR PF11085.3 EIE86798.1 - 0.0027 17.2 5.2 0.0058 16.1 0.2 2.4 2 0 0 2 2 2 1 Conserved membrane protein YqhR SKG6 PF08693.5 EIE86798.1 - 0.0043 16.3 0.9 0.01 15.1 0.7 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain VSP PF03302.8 EIE86798.1 - 0.019 13.6 2.3 0.033 12.8 1.6 1.3 1 0 0 1 1 1 0 Giardia variant-specific surface protein Ni_hydr_CYTB PF01292.15 EIE86798.1 - 0.055 12.8 2.8 0.031 13.6 0.4 1.7 2 0 0 2 2 2 0 Prokaryotic cytochrome b561 Syndecan PF01034.15 EIE86798.1 - 0.11 12.1 0.2 0.11 12.1 0.1 2.6 3 0 0 3 3 2 0 Syndecan domain Amnionless PF14828.1 EIE86798.1 - 0.12 10.9 0.1 0.21 10.0 0.1 1.4 1 0 0 1 1 1 0 Amnionless RVT_1 PF00078.22 EIE86799.1 - 0.00017 21.0 0.1 0.00027 20.3 0.0 1.4 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Cytomega_UL84 PF06284.6 EIE86800.1 - 0.006 15.0 3.0 0.0067 14.8 2.1 1.2 1 0 0 1 1 1 1 Cytomegalovirus UL84 protein CsbD PF05532.7 EIE86801.1 - 0.28 10.9 1.5 0.55 9.9 1.0 1.4 1 0 0 1 1 1 0 CsbD-like Mito_carr PF00153.22 EIE86802.1 - 0.0043 16.7 0.0 5.3 6.8 0.0 3.1 3 0 0 3 3 3 2 Mitochondrial carrier protein BSP_II PF05432.6 EIE86802.1 - 0.018 14.3 3.0 0.022 14.0 2.1 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) TCO89 PF10452.4 EIE86802.1 - 0.13 11.1 1.4 0.16 10.8 1.0 1.1 1 0 0 1 1 1 0 TORC1 subunit TCO89 E1-E2_ATPase PF00122.15 EIE86803.1 - 4.8e-66 222.0 5.6 2.4e-65 219.7 2.7 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EIE86803.1 - 5.3e-41 140.1 3.1 5.3e-41 140.1 2.1 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EIE86803.1 - 4.6e-27 95.8 0.0 1.1e-25 91.3 0.0 2.8 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EIE86803.1 - 3.3e-20 71.8 0.1 7.6e-20 70.6 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EIE86803.1 - 4.4e-16 58.0 0.1 8.9e-15 53.9 0.0 2.5 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EIE86803.1 - 9.8e-16 58.4 0.0 2.2e-15 57.3 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EIE86803.1 - 2e-05 24.3 0.8 0.00082 19.0 0.7 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase PsbN PF02468.10 EIE86805.1 - 2.4 7.8 4.5 0.82 9.3 0.9 1.9 2 0 0 2 2 2 0 Photosystem II reaction centre N protein (psbN) GST_N_3 PF13417.1 EIE86807.1 - 1.2e-09 38.2 0.0 2.3e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIE86807.1 - 2.6e-07 30.5 0.0 1.3e-06 28.3 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EIE86807.1 - 9e-06 25.7 0.0 2.7e-05 24.2 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIE86807.1 - 9.4e-06 25.4 0.0 1.8e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EIE86807.1 - 1e-05 25.4 0.0 1.7e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EIE86807.1 - 0.0063 16.9 0.0 0.0093 16.4 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain NUC153 PF08159.7 EIE86807.1 - 0.17 11.4 0.7 16 5.1 0.1 2.4 2 0 0 2 2 2 0 NUC153 domain CBFD_NFYB_HMF PF00808.18 EIE86808.1 - 5.4e-11 42.3 0.1 8.5e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone RNA_pol_Rpc34 PF05158.7 EIE86808.1 - 0.0033 16.6 0.6 0.0037 16.4 0.4 1.1 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit Histone PF00125.19 EIE86808.1 - 0.012 15.6 0.0 0.017 15.2 0.0 1.2 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Peptidase_S49_N PF08496.5 EIE86808.1 - 0.041 13.6 1.4 0.053 13.3 0.9 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Astro_capsid PF03115.9 EIE86808.1 - 0.09 11.0 2.6 0.092 10.9 1.8 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor rve PF00665.21 EIE86809.1 - 1.4e-23 83.2 0.0 3.2e-23 82.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 EIE86809.1 - 1.3e-12 47.1 0.3 2.5e-12 46.2 0.2 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 EIE86809.1 - 0.0033 16.8 0.1 0.006 15.9 0.0 1.5 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger RVT_1 PF00078.22 EIE86810.1 - 2.2e-26 92.5 0.0 4.5e-26 91.5 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Osmo_CC PF08946.5 EIE86811.1 - 0.42 10.6 3.1 1.3 9.1 0.4 2.3 2 0 0 2 2 2 0 Osmosensory transporter coiled coil zf-CCHC PF00098.18 EIE86812.1 - 1.8e-05 24.4 10.5 0.0025 17.6 1.0 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 EIE86812.1 - 0.044 13.4 8.2 0.039 13.6 1.3 2.4 2 0 0 2 2 2 0 Zinc knuckle Zn_ribbon_2 PF12674.2 EIE86812.1 - 3.9 7.8 8.6 16 5.9 1.1 2.5 1 1 1 2 2 2 0 Putative zinc ribbon domain RVT_1 PF00078.22 EIE86813.1 - 3.3e-17 62.5 0.0 5.6e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 EIE86813.1 - 7.9e-07 29.4 0.0 4.9e-06 26.9 0.0 2.4 3 0 0 3 3 3 1 Aspartyl protease gag-asp_proteas PF13975.1 EIE86813.1 - 0.00036 20.2 0.0 0.00076 19.2 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.12 EIE86814.1 - 7e-07 29.2 1.2 2.3e-06 27.5 0.1 2.0 2 0 0 2 2 2 1 Retrotransposon gag protein UBN2 PF14223.1 EIE86814.1 - 3.1e-05 23.7 0.3 0.062 13.0 0.0 2.5 2 0 0 2 2 2 2 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 EIE86814.1 - 3.3e-05 23.4 0.3 0.00028 20.4 0.0 2.2 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type HTH_Tnp_Tc3_2 PF01498.13 EIE86815.1 - 4.3e-11 42.7 2.1 5.7e-11 42.3 1.4 1.3 1 0 0 1 1 1 1 Transposase Clathrin PF00637.15 EIE86815.1 - 0.014 15.0 0.2 0.018 14.6 0.1 1.1 1 0 0 1 1 1 0 Region in Clathrin and VPS DDE_3 PF13358.1 EIE86816.1 - 4e-16 59.0 0.2 5e-16 58.7 0.1 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EIE86817.1 - 1.5e-09 37.7 2.6 2.7e-09 36.9 0.7 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease FAM165 PF14981.1 EIE86818.1 - 0.51 9.8 3.2 0.45 10.0 0.2 2.0 1 1 1 2 2 2 0 FAM165 family Mto2_bdg PF12808.2 EIE86819.1 - 0.11 12.6 6.4 0.64 10.1 0.4 3.3 3 0 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Transposase_21 PF02992.9 EIE86820.1 - 8e-25 87.2 0.1 1.7e-24 86.1 0.0 1.5 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 EIE86820.1 - 4e-05 23.0 0.3 8.1e-05 22.0 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) HTH_23 PF13384.1 EIE86821.1 - 0.00016 21.1 0.0 0.00021 20.7 0.0 1.2 1 0 0 1 1 1 1 Homeodomain-like domain Sigma70_r4_2 PF08281.7 EIE86821.1 - 0.015 14.7 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_28 PF13518.1 EIE86821.1 - 0.021 14.8 0.0 0.028 14.4 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.1 EIE86821.1 - 0.053 12.6 0.0 0.14 11.3 0.0 1.6 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 GerE PF00196.14 EIE86821.1 - 0.058 12.7 0.0 0.076 12.3 0.0 1.2 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family HTH_29 PF13551.1 EIE86821.1 - 0.099 12.7 0.0 0.13 12.4 0.0 1.3 1 1 0 1 1 1 0 Winged helix-turn helix HTH_Tnp_1 PF01527.15 EIE86821.1 - 0.11 12.4 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 Transposase HTH_17 PF12728.2 EIE86821.1 - 0.14 12.4 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain DDE_3 PF13358.1 EIE86822.1 - 3.7e-16 59.1 0.2 4.8e-16 58.8 0.2 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EIE86823.1 - 3.6e-17 62.4 0.3 2.1e-16 59.9 0.0 2.3 3 0 0 3 3 3 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE86823.1 - 3.5e-11 42.9 0.5 8.6e-11 41.7 0.3 1.7 1 0 0 1 1 1 1 Transposase DUF3306 PF11748.3 EIE86824.1 - 0.056 14.1 0.7 0.076 13.6 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) BUD22 PF09073.5 EIE86824.1 - 0.26 10.2 7.6 0.32 10.0 5.3 1.0 1 0 0 1 1 1 0 BUD22 FAM176 PF14851.1 EIE86824.1 - 0.57 9.8 3.6 0.73 9.5 2.5 1.2 1 0 0 1 1 1 0 FAM176 family DDE_3 PF13358.1 EIE86825.1 - 1.6e-21 76.6 0.4 2.1e-21 76.1 0.3 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Basic PF01586.11 EIE86825.1 - 0.17 12.6 1.1 0.61 10.8 0.1 2.2 2 1 0 2 2 2 0 Myogenic Basic domain Med15 PF09606.5 EIE86826.1 - 0.033 12.4 14.3 0.047 11.8 9.9 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DEC-1_N PF04625.8 EIE86826.1 - 1.1 7.9 16.8 2 7.0 11.7 1.5 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Transposase_21 PF02992.9 EIE86827.1 - 6.8e-22 77.6 0.0 1.5e-21 76.5 0.0 1.5 1 0 0 1 1 1 1 Transposase family tnp2 DUF1258 PF06869.7 EIE86827.1 - 0.0025 16.9 0.0 0.0041 16.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) RVT_1 PF00078.22 EIE86829.1 - 4.8e-23 81.6 3.1 6.7e-23 81.1 0.6 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.12 EIE86829.1 - 2.9e-18 65.7 0.6 9.5e-18 64.0 0.4 2.0 1 0 0 1 1 1 1 Retrotransposon gag protein Asp_protease_2 PF13650.1 EIE86829.1 - 1.6e-06 28.5 0.0 3.4e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EIE86829.1 - 4.3e-05 23.2 0.0 9.1e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 EIE86829.1 - 0.00016 21.6 0.0 0.00032 20.6 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.15 EIE86829.1 - 0.00052 19.8 0.0 0.0016 18.2 0.0 1.9 1 0 0 1 1 1 1 Retroviral aspartyl protease Peptidase_A3 PF02160.10 EIE86829.1 - 0.0011 18.5 0.3 0.015 14.8 0.1 2.6 2 1 0 2 2 2 1 Cauliflower mosaic virus peptidase (A3) Asp_protease PF09668.5 EIE86829.1 - 0.017 14.7 0.0 0.041 13.4 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC PF00098.18 EIE86829.1 - 0.041 13.8 0.6 0.087 12.7 0.4 1.6 1 0 0 1 1 1 0 Zinc knuckle rve PF00665.21 EIE86830.1 - 4.3e-20 72.0 0.0 7.3e-20 71.2 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.1 EIE86830.1 - 0.0075 16.2 0.2 0.021 14.7 0.0 1.8 2 0 0 2 2 2 1 DDE domain rve_3 PF13683.1 EIE86830.1 - 0.066 12.7 0.0 0.23 11.0 0.0 2.0 1 0 0 1 1 1 0 Integrase core domain Transposase_21 PF02992.9 EIE86831.1 - 1.9e-21 76.1 0.0 3.6e-21 75.3 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DUF1258 PF06869.7 EIE86831.1 - 0.0055 15.8 0.0 0.0096 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) FKBP_N PF01346.13 EIE86832.1 - 0.0029 17.6 1.0 0.0029 17.6 0.7 1.5 2 0 0 2 2 2 1 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase LAG1-DNAbind PF09271.6 EIE86832.1 - 0.025 15.0 0.3 0.05 14.0 0.2 1.5 1 0 0 1 1 1 0 LAG1, DNA binding HTH_37 PF13744.1 EIE86832.1 - 0.82 9.5 6.6 17 5.2 3.7 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain RRF_GI PF12614.3 EIE86833.1 - 0.022 14.5 0.1 0.023 14.5 0.1 1.2 1 0 0 1 1 1 0 Ribosome recycling factor zf-CCHC PF00098.18 EIE86835.1 - 5.4e-11 41.8 9.5 7.3e-06 25.6 0.6 2.3 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.24 EIE86835.1 - 1.1e-07 31.3 0.1 2e-07 30.5 0.1 1.4 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 EIE86835.1 - 3.9e-05 23.1 0.1 0.0001 21.8 0.0 1.8 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.1 EIE86835.1 - 0.0023 17.6 6.7 0.031 14.0 1.0 2.5 1 1 1 2 2 2 2 Zinc knuckle DnaJ_CXXCXGXG PF00684.14 EIE86835.1 - 0.004 17.1 6.5 0.0078 16.2 4.5 1.4 1 0 0 1 1 1 1 DnaJ central domain zf-CCHC_2 PF13696.1 EIE86835.1 - 0.0089 15.4 0.7 0.0089 15.4 0.5 2.5 1 1 1 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.1 EIE86835.1 - 1.1 9.0 10.0 3.5 7.3 1.9 2.6 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_6 PF15288.1 EIE86835.1 - 1.2 8.8 9.6 1.6 8.4 0.4 2.6 1 1 1 2 2 2 0 Zinc knuckle GST_C_2 PF13410.1 EIE86836.1 - 4e-06 26.6 0.0 4.5e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EIE86836.1 - 8.3e-06 25.7 0.0 9.3e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EIE86836.1 - 0.0091 16.4 0.0 0.012 16.0 0.0 1.3 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain WWbp PF10349.4 EIE86837.1 - 3.4e-08 34.3 0.6 9.4e-08 32.9 0.4 1.8 1 1 0 1 1 1 1 WW-domain ligand protein Vps36_ESCRT-II PF11605.3 EIE86837.1 - 0.0017 18.1 0.0 0.0046 16.7 0.0 1.8 1 1 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 GRAM PF02893.15 EIE86837.1 - 0.0057 16.1 0.0 0.0081 15.6 0.0 1.4 1 0 0 1 1 1 1 GRAM domain Prok-E2_B PF14461.1 EIE86839.1 - 0.028 14.1 0.5 0.07 12.8 0.2 1.8 2 0 0 2 2 2 0 Prokaryotic E2 family B Abhydrolase_6 PF12697.2 EIE86840.1 - 2.4e-32 112.6 0.0 2.8e-32 112.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIE86840.1 - 1.5e-19 70.5 0.0 5.6e-18 65.3 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIE86840.1 - 1e-13 51.2 0.0 1.1e-12 47.9 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EIE86840.1 - 9e-06 25.2 0.0 1.2e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.16 EIE86840.1 - 0.00028 20.1 0.0 0.78 8.9 0.0 2.5 2 1 0 2 2 2 2 Prolyl oligopeptidase family Esterase_phd PF10503.4 EIE86840.1 - 0.0004 19.7 0.0 0.23 10.6 0.0 2.2 2 0 0 2 2 2 2 Esterase PHB depolymerase Tannase PF07519.6 EIE86840.1 - 0.0023 16.7 0.0 0.12 11.0 0.0 2.1 2 0 0 2 2 2 1 Tannase and feruloyl esterase Thioesterase PF00975.15 EIE86840.1 - 0.0042 17.3 0.0 0.032 14.4 0.0 2.1 2 1 0 2 2 2 1 Thioesterase domain Abhydrolase_3 PF07859.8 EIE86840.1 - 0.022 14.3 0.1 0.066 12.7 0.0 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.13 EIE86840.1 - 0.033 13.4 0.0 0.68 9.1 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_4 PF08386.5 EIE86840.1 - 0.054 13.3 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 TAP-like protein Abhydrolase_2 PF02230.11 EIE86840.1 - 0.094 12.1 0.0 0.71 9.2 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase PGAP1 PF07819.8 EIE86840.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Cyclin_N PF00134.18 EIE86841.1 - 2e-09 37.0 0.2 2.7e-09 36.6 0.1 1.3 1 1 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 EIE86841.1 - 7.7e-09 36.1 0.4 1.4e-08 35.3 0.3 1.5 1 1 0 1 1 1 1 Cyclin M20_dimer PF07687.9 EIE86842.1 - 1.8e-10 40.5 0.0 3.4e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.23 EIE86842.1 - 0.0027 17.2 0.0 0.0089 15.5 0.0 1.7 1 1 1 2 2 2 1 Peptidase family M20/M25/M40 AMP-binding PF00501.23 EIE86843.1 - 6e-79 265.3 0.0 7.6e-79 265.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EIE86843.1 - 8.9e-17 61.8 0.3 2.9e-16 60.1 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain PP2C PF00481.16 EIE86844.1 - 4.5e-11 42.6 0.1 5.8e-11 42.2 0.1 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C Ras PF00071.17 EIE86845.1 - 1.3e-54 184.0 0.0 1.5e-54 183.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIE86845.1 - 6e-15 55.7 0.0 9.5e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIE86845.1 - 6.3e-08 32.0 0.0 9.1e-08 31.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EIE86845.1 - 0.0031 16.7 0.0 0.0046 16.2 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EIE86845.1 - 0.073 12.1 0.0 0.09 11.8 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Ank_2 PF12796.2 EIE86846.1 - 8.1e-41 138.2 0.1 1.9e-11 44.1 0.0 4.8 3 1 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EIE86846.1 - 7.5e-37 124.5 3.5 5e-10 39.2 0.0 5.8 5 1 1 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.25 EIE86846.1 - 1.4e-33 112.9 8.0 2.3e-05 23.9 0.1 7.8 8 0 0 8 8 8 6 Ankyrin repeat Ank_4 PF13637.1 EIE86846.1 - 1.2e-29 102.1 6.4 4.7e-06 26.9 0.0 7.6 4 3 3 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIE86846.1 - 6.4e-22 75.4 3.7 0.0051 16.9 0.0 8.7 8 0 0 8 8 8 5 Ankyrin repeat DUF948 PF06103.6 EIE86846.1 - 3.7 7.4 15.8 2.7 7.9 0.9 5.1 4 2 0 4 4 4 0 Bacterial protein of unknown function (DUF948) zf-MYND PF01753.13 EIE86847.1 - 3.5e-05 23.5 12.5 3.5e-05 23.5 8.6 2.2 2 0 0 2 2 2 1 MYND finger TPR_1 PF00515.23 EIE86847.1 - 0.00045 19.7 0.2 0.0021 17.5 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 EIE86847.1 - 0.0013 18.5 0.1 0.0075 16.1 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 EIE86847.1 - 0.0014 18.2 0.1 0.024 14.4 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EIE86847.1 - 0.0098 15.8 0.3 0.025 14.5 0.0 1.7 2 0 0 2 2 2 1 Tetratricopeptide repeat zf-ribbon_3 PF13248.1 EIE86847.1 - 0.01 15.0 1.0 0.034 13.3 0.7 1.9 1 0 0 1 1 1 0 zinc-ribbon domain MIT PF04212.13 EIE86847.1 - 0.023 14.5 0.0 0.14 12.0 0.0 2.2 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain Aminotran_5 PF00266.14 EIE86848.1 - 7e-33 113.8 0.0 9.5e-33 113.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.14 EIE86848.1 - 0.02 14.7 0.0 0.049 13.4 0.0 1.6 1 0 0 1 1 1 0 B12 binding domain WWE PF02825.15 EIE86850.1 - 0.037 13.4 0.1 0.11 11.9 0.0 1.8 1 1 0 1 1 1 0 WWE domain Na_H_Exchanger PF00999.16 EIE86851.1 - 4.5e-47 160.3 18.7 6.2e-47 159.9 13.0 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF3560 PF12083.3 EIE86851.1 - 0.072 13.1 1.2 0.4 10.7 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3560) DUF3464 PF11947.3 EIE86851.1 - 0.57 9.6 4.4 0.18 11.2 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3464) YrhC PF14143.1 EIE86851.1 - 1.2 9.0 4.6 0.53 10.2 0.2 2.5 2 0 0 2 2 2 0 YrhC-like protein DUF4231 PF14015.1 EIE86852.1 - 0.93 9.5 8.7 0.38 10.7 0.3 3.2 1 1 0 2 2 2 0 Protein of unknown function (DUF4231) RCR PF12273.3 EIE86852.1 - 1.1 9.7 0.1 1.1 9.7 0.0 2.3 3 0 0 3 3 3 0 Chitin synthesis regulation, resistance to Congo red DUF2842 PF11003.3 EIE86852.1 - 1.6 8.6 10.5 0.13 12.1 2.3 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2842) DUF1469 PF07332.6 EIE86852.1 - 5.1 6.8 12.9 0.1 12.3 0.3 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF1469) MFS_1 PF07690.11 EIE86852.1 - 8.3 5.0 15.3 30 3.1 9.8 2.2 1 1 0 1 1 1 0 Major Facilitator Superfamily COX6B PF02297.12 EIE86853.1 - 0.0083 16.1 0.9 0.0083 16.1 0.6 2.1 1 1 1 2 2 2 1 Cytochrome oxidase c subunit VIb Cmc1 PF08583.5 EIE86853.1 - 0.011 15.4 4.6 0.012 15.3 2.3 1.6 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like DUF3128 PF11326.3 EIE86853.1 - 0.012 15.6 1.2 0.018 15.1 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3128) Ndufs5 PF10200.4 EIE86853.1 - 0.029 14.3 3.0 0.041 13.8 2.1 1.4 1 1 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Pet191_N PF10203.4 EIE86853.1 - 0.033 14.2 1.2 0.06 13.4 0.8 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 NDUF_B7 PF05676.8 EIE86853.1 - 1 8.7 7.6 0.45 9.9 2.8 1.9 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) START PF01852.14 EIE86854.1 - 4e-16 58.9 0.1 2.6e-13 49.7 0.0 2.3 2 0 0 2 2 2 2 START domain BOFC_N PF08977.5 EIE86854.1 - 0.087 12.6 2.0 0.27 11.1 0.3 2.3 2 0 0 2 2 2 0 Bypass of Forespore C, N terminal YfzA PF14118.1 EIE86854.1 - 0.13 12.3 0.0 6.3 6.9 0.0 3.0 3 0 0 3 3 3 0 YfzA-like protein DUF605 PF04652.11 EIE86854.1 - 2.6 7.3 12.6 4.2 6.6 8.8 1.2 1 0 0 1 1 1 0 Vta1 like DDE_3 PF13358.1 EIE86855.1 - 9.9e-10 38.3 0.3 1e-07 31.8 0.0 2.4 2 0 0 2 2 2 2 DDE superfamily endonuclease HTH_29 PF13551.1 EIE86855.1 - 0.011 15.9 0.1 0.02 15.0 0.1 1.5 1 0 0 1 1 1 0 Winged helix-turn helix zf-C2H2 PF00096.21 EIE86855.1 - 0.012 15.8 1.3 0.033 14.5 0.9 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIE86855.1 - 0.076 13.3 0.3 0.21 12.0 0.2 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EIE86855.1 - 3.2 8.0 8.3 0.14 12.3 1.2 2.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding HTH_Tnp_Tc3_2 PF01498.13 EIE86856.1 - 7.2e-16 58.0 1.1 2.3e-15 56.4 0.8 1.9 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.1 EIE86856.1 - 3.8e-13 49.4 1.0 7.9e-13 48.3 0.7 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 EIE86856.1 - 1.9e-08 34.4 0.4 3.2e-07 30.4 0.0 2.8 2 1 1 3 3 3 1 Winged helix-turn helix HTH_23 PF13384.1 EIE86856.1 - 0.00022 20.7 0.0 0.00094 18.7 0.0 2.1 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.1 EIE86856.1 - 0.00064 19.6 0.0 0.0023 17.9 0.0 2.0 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.1 EIE86856.1 - 0.0078 15.5 0.0 0.088 12.2 0.0 2.5 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_17 PF12728.2 EIE86856.1 - 0.012 15.8 0.6 0.19 11.9 0.0 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_38 PF13936.1 EIE86856.1 - 0.029 13.9 0.0 0.1 12.1 0.0 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain SpoIIID PF12116.3 EIE86856.1 - 0.031 14.2 0.0 0.11 12.3 0.0 2.0 2 0 0 2 2 2 0 Stage III sporulation protein D HTH_IclR PF09339.5 EIE86856.1 - 0.048 13.2 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 IclR helix-turn-helix domain Orthopox_A5L PF06193.6 EIE86858.1 - 0.035 14.0 1.5 0.037 13.9 1.0 1.1 1 0 0 1 1 1 0 Orthopoxvirus A5L protein-like Aldose_epim PF01263.15 EIE86861.1 - 2e-23 82.9 0.0 2.2e-23 82.8 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase RVT_1 PF00078.22 EIE86863.1 - 6.5e-10 38.7 0.0 1.5e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2834 PF11196.3 EIE86864.1 - 6.3e-05 23.0 4.8 0.022 14.9 0.3 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF2834) Inositol_P PF00459.20 EIE86865.1 - 7.7e-60 202.4 0.1 1.2e-59 201.8 0.0 1.2 1 0 0 1 1 1 1 Inositol monophosphatase family MutS_I PF01624.15 EIE86865.1 - 0.12 12.3 0.0 0.41 10.6 0.0 1.9 2 0 0 2 2 2 0 MutS domain I ALS_ss_C PF10369.4 EIE86866.1 - 5.5e-20 70.8 0.0 1.4e-17 63.1 0.0 2.4 2 0 0 2 2 2 2 Small subunit of acetolactate synthase ACT PF01842.20 EIE86866.1 - 1.4e-10 40.4 0.0 2.5e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.1 EIE86866.1 - 8.1e-09 35.1 0.0 1.5e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 ACT domain ASXH PF13919.1 EIE86867.1 - 2e-12 47.0 0.7 2e-12 47.0 0.5 2.5 2 0 0 2 2 2 1 Asx homology domain GAS2 PF02187.12 EIE86868.1 - 1.8e-06 27.6 0.0 4.9e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain CH PF00307.26 EIE86869.1 - 2.5e-08 33.8 0.0 3.1e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Calponin homology (CH) domain Shisa PF13908.1 EIE86871.1 - 2.2e-05 24.7 0.3 2.2e-05 24.7 0.2 1.8 1 1 1 2 2 2 1 Wnt and FGF inhibitory regulator Mid2 PF04478.7 EIE86871.1 - 0.025 14.0 2.0 0.043 13.2 1.4 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Herpes_gE PF02480.11 EIE86871.1 - 0.042 12.1 0.2 0.1 10.8 0.1 1.6 1 1 0 1 1 1 0 Alphaherpesvirus glycoprotein E Na_Ca_ex PF01699.19 EIE86871.1 - 0.049 13.2 1.2 0.088 12.4 0.8 1.3 1 0 0 1 1 1 0 Sodium/calcium exchanger protein TIG PF01833.19 EIE86872.1 - 1.3e-07 31.5 0.0 2.7e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 IPT/TIG domain BTD PF09270.5 EIE86872.1 - 0.0039 16.9 0.0 0.46 10.2 0.0 2.3 1 1 1 2 2 2 2 Beta-trefoil DNA-binding domain ARPC4 PF05856.7 EIE86873.1 - 1.3e-77 259.0 4.5 1.4e-77 258.8 3.1 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) DUF3050 PF11251.3 EIE86874.1 - 0.014 14.6 1.9 0.14 11.3 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3050) DUF2175 PF09943.4 EIE86874.1 - 0.15 12.1 1.4 0.56 10.2 0.5 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) UBACT PF02134.16 EIE86876.1 - 4.8e-27 93.3 0.6 1.4e-26 91.8 0.4 1.8 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EIE86876.1 - 1.1e-19 69.5 4.3 1.1e-19 69.5 3.0 1.9 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site UAE_UbL PF14732.1 EIE86876.1 - 3.2e-07 30.3 0.3 3.2e-07 30.3 0.2 2.7 3 0 0 3 3 3 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain ThiF PF00899.16 EIE86876.1 - 1.2e-06 28.3 0.0 7.4e-06 25.8 0.0 2.2 2 0 0 2 2 2 1 ThiF family LBP_BPI_CETP PF01273.20 EIE86876.1 - 0.022 14.1 0.1 0.037 13.3 0.1 1.3 1 0 0 1 1 1 0 LBP / BPI / CETP family, N-terminal domain LETM1 PF07766.8 EIE86877.1 - 2.5e-105 351.3 1.4 2.5e-105 351.3 1.0 2.0 2 0 0 2 2 2 1 LETM1-like protein SAP PF02037.22 EIE86877.1 - 0.0015 17.9 0.0 0.059 12.8 0.0 2.6 2 0 0 2 2 2 1 SAP domain Fer4_19 PF06902.6 EIE86879.1 - 0.028 14.2 0.0 0.06 13.1 0.0 1.5 1 0 0 1 1 1 0 Divergent 4Fe-4S mono-cluster Lactamase_B_2 PF12706.2 EIE86880.1 - 5.2e-21 75.0 0.0 7.9e-21 74.4 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EIE86880.1 - 9.8e-06 25.3 0.0 0.00011 21.9 0.0 2.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain AstE_AspA PF04952.9 EIE86881.1 - 9.7e-24 83.7 0.0 1.7e-23 82.9 0.0 1.3 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family HutD PF05962.6 EIE86881.1 - 1.5e-17 63.9 0.0 1.5e-16 60.6 0.0 2.1 1 1 1 2 2 2 1 HutD Peptidase_M14 PF00246.19 EIE86881.1 - 0.083 12.4 0.1 0.19 11.3 0.1 1.5 1 1 0 1 1 1 0 Zinc carboxypeptidase ECIST_Cterm PF14784.1 EIE86882.1 - 0.061 13.2 1.5 0.075 12.9 0.1 1.8 1 1 1 2 2 2 0 C-terminal domain of the ECSIT protein GST_N_3 PF13417.1 EIE86883.1 - 2.1e-13 50.2 0.0 4.6e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIE86883.1 - 2.6e-10 40.1 0.0 5.2e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EIE86883.1 - 0.00035 20.5 0.0 0.0006 19.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EIE86883.1 - 0.00075 19.3 0.1 0.0013 18.5 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EIE86883.1 - 0.0034 17.5 0.0 0.0082 16.2 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EIE86883.1 - 0.076 13.5 0.1 0.31 11.5 0.1 2.0 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF3786 PF12654.2 EIE86883.1 - 0.09 12.0 0.3 0.19 10.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3786) Transaldolase PF00923.14 EIE86885.1 - 3.2e-103 344.8 0.1 3.6e-103 344.6 0.0 1.0 1 0 0 1 1 1 1 Transaldolase APOBEC_N PF08210.6 EIE86885.1 - 0.087 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 APOBEC-like N-terminal domain DUF221 PF02714.10 EIE86886.1 - 2.7e-100 335.3 21.3 4.6e-100 334.6 14.7 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF221 DUF4463 PF14703.1 EIE86886.1 - 3.5e-11 43.4 0.0 8.1e-11 42.2 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) DUF3779 PF12621.3 EIE86886.1 - 1.1e-09 37.9 0.1 2.5e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Phosphate metabolism protein RSN1_TM PF13967.1 EIE86886.1 - 1.5e-09 37.6 1.7 1.5e-09 37.6 1.2 3.0 4 1 0 4 4 4 1 Late exocytosis, associated with Golgi transport HTH_28 PF13518.1 EIE86888.1 - 0.01 15.8 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain YolD PF08863.5 EIE86888.1 - 0.017 14.9 0.5 0.032 14.0 0.2 1.6 1 1 0 1 1 1 0 YolD-like protein RRF_GI PF12614.3 EIE86888.1 - 0.045 13.5 0.4 0.075 12.8 0.2 1.4 1 1 0 1 1 1 0 Ribosome recycling factor HTH_23 PF13384.1 EIE86888.1 - 0.067 12.8 0.0 0.73 9.5 0.0 2.1 1 1 1 2 2 2 0 Homeodomain-like domain HTH_17 PF12728.2 EIE86888.1 - 0.067 13.4 0.0 0.15 12.3 0.0 1.6 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_IclR PF09339.5 EIE86888.1 - 0.091 12.3 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain DNA_ligase_A_M PF01068.16 EIE86888.1 - 0.1 11.9 0.8 0.13 11.5 0.5 1.1 1 0 0 1 1 1 0 ATP dependent DNA ligase domain HTH_29 PF13551.1 EIE86888.1 - 0.12 12.4 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn helix zf-C2H2 PF00096.21 EIE86891.1 - 2.6e-16 58.9 19.8 1.1e-05 25.5 0.7 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIE86891.1 - 2.4e-14 52.8 16.4 1.2e-07 31.6 0.6 4.3 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 EIE86891.1 - 8.6e-11 41.3 22.0 0.00011 22.3 0.4 3.8 4 0 0 4 4 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EIE86891.1 - 3e-05 24.0 12.3 0.0045 17.1 0.3 3.7 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 EIE86891.1 - 0.0058 16.7 3.9 2.6 8.2 0.0 2.7 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.2 EIE86891.1 - 0.012 15.7 10.7 0.31 11.3 0.5 3.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-BED PF02892.10 EIE86891.1 - 0.017 14.8 6.9 0.35 10.6 0.0 3.5 2 1 1 3 3 3 0 BED zinc finger zf-C2H2_6 PF13912.1 EIE86891.1 - 0.044 13.7 11.0 0.19 11.6 0.3 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2HC_2 PF13913.1 EIE86891.1 - 0.047 13.3 3.5 0.093 12.4 0.2 2.7 2 0 0 2 2 2 0 zinc-finger of a C2HC-type PyrI_C PF02748.10 EIE86891.1 - 0.11 11.9 2.7 1.2 8.6 0.0 3.1 2 1 1 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-AN1 PF01428.11 EIE86891.1 - 0.35 10.7 9.1 6.8 6.6 1.8 3.0 1 1 1 2 2 2 0 AN1-like Zinc finger LIM PF00412.17 EIE86891.1 - 0.61 10.1 9.9 1.1 9.4 1.1 2.7 3 0 0 3 3 2 0 LIM domain PX PF00787.19 EIE86892.1 - 8.2e-20 70.6 0.4 1.7e-19 69.6 0.3 1.5 1 0 0 1 1 1 1 PX domain Pep_deformylase PF01327.16 EIE86892.1 - 0.063 12.6 0.1 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Polypeptide deformylase GPI-anchored PF10342.4 EIE86894.1 - 2.8e-05 24.5 0.7 2.8e-05 24.5 0.5 1.8 1 1 1 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Amidohydro_4 PF13147.1 EIE86895.1 - 9.9e-25 88.0 2.4 1.3e-09 38.4 0.0 4.0 4 0 0 4 4 4 3 Amidohydrolase Amidohydro_1 PF01979.15 EIE86895.1 - 3.9e-18 66.2 1.6 1.6e-09 37.8 0.0 3.7 4 0 0 4 4 4 3 Amidohydrolase family Amidohydro_5 PF13594.1 EIE86895.1 - 5.2e-13 48.6 3.2 3.5e-11 42.7 0.4 3.3 3 0 0 3 3 3 1 Amidohydrolase Amidohydro_3 PF07969.6 EIE86895.1 - 1.2e-12 47.7 2.0 3.2e-07 29.9 0.0 3.6 3 1 0 3 3 3 3 Amidohydrolase family Tubulin_3 PF14881.1 EIE86896.1 - 0.12 11.8 0.9 0.16 11.3 0.6 1.2 1 0 0 1 1 1 0 Tubulin domain MCM PF00493.18 EIE86897.1 - 6.4e-135 449.2 0.1 1.6e-134 447.9 0.0 1.7 2 0 0 2 2 2 1 MCM2/3/5 family MCM_N PF14551.1 EIE86897.1 - 2.4e-26 92.6 0.9 1.4e-25 90.1 0.3 2.4 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EIE86897.1 - 1.2e-07 31.1 0.1 9.5e-06 24.9 0.0 2.7 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EIE86897.1 - 3.3e-06 26.8 0.1 1.5e-05 24.7 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EIE86897.1 - 0.019 14.5 0.4 0.093 12.3 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) 4HB_MCP_1 PF12729.2 EIE86897.1 - 0.036 13.4 4.6 0.86 8.9 0.0 3.0 2 1 0 2 2 2 0 Four helix bundle sensory module for signal transduction NIPSNAP PF07978.8 EIE86897.1 - 0.055 13.4 0.0 0.21 11.6 0.0 2.0 2 0 0 2 2 2 0 NIPSNAP Sigma54_activat PF00158.21 EIE86897.1 - 0.058 12.8 0.0 0.55 9.6 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain Zn-ribbon_8 PF09723.5 EIE86897.1 - 0.086 12.8 1.0 0.21 11.5 0.7 1.6 1 0 0 1 1 1 0 Zinc ribbon domain HSF_DNA-bind PF00447.12 EIE86898.1 - 6.3e-35 119.4 1.2 6.3e-35 119.4 0.8 2.1 2 0 0 2 2 2 1 HSF-type DNA-binding Response_reg PF00072.19 EIE86898.1 - 4e-25 87.9 0.5 1e-24 86.6 0.3 1.8 1 0 0 1 1 1 1 Response regulator receiver domain DUF1759 PF03564.10 EIE86898.1 - 0.0073 16.1 3.5 0.1 12.3 1.4 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF1759) Prominin PF05478.6 EIE86898.1 - 0.011 13.3 3.2 0.015 12.8 2.2 1.1 1 0 0 1 1 1 0 Prominin IFT20 PF14931.1 EIE86898.1 - 0.032 14.1 2.8 0.058 13.2 2.0 1.4 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 Macoilin PF09726.4 EIE86898.1 - 0.044 12.0 5.7 0.0098 14.2 1.8 1.4 1 1 0 1 1 1 0 Transmembrane protein CCDC84 PF14968.1 EIE86898.1 - 0.08 12.4 1.3 0.11 11.9 0.9 1.2 1 0 0 1 1 1 0 Coiled coil protein 84 DMPK_coil PF08826.5 EIE86898.1 - 0.13 12.1 0.8 0.3 11.0 0.5 1.5 1 0 0 1 1 1 0 DMPK coiled coil domain like V_ATPase_I PF01496.14 EIE86898.1 - 0.16 9.7 2.3 0.21 9.4 1.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG17 PF04108.7 EIE86898.1 - 0.27 9.9 4.5 0.45 9.2 3.1 1.3 1 0 0 1 1 1 0 Autophagy protein Apg17 TMPIT PF07851.8 EIE86898.1 - 0.57 9.1 3.3 0.86 8.6 2.3 1.2 1 0 0 1 1 1 0 TMPIT-like protein CENP-Q PF13094.1 EIE86898.1 - 1.3 9.0 6.6 0.83 9.6 3.4 1.6 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit TIP120 PF08623.5 EIE86899.1 - 1.5e-57 193.8 0.9 1.5e-57 193.8 0.6 4.9 5 1 0 6 6 6 1 TATA-binding protein interacting (TIP20) HEAT PF02985.17 EIE86899.1 - 7.2e-21 72.3 13.8 0.0041 17.0 0.0 14.0 15 0 0 15 15 14 4 HEAT repeat HEAT_2 PF13646.1 EIE86899.1 - 2.5e-20 72.5 13.9 3.6e-05 23.9 0.2 10.4 6 4 3 10 10 10 5 HEAT repeats HEAT_EZ PF13513.1 EIE86899.1 - 9.2e-14 51.4 10.5 0.028 14.9 0.1 11.7 9 4 5 14 14 14 3 HEAT-like repeat Cnd1 PF12717.2 EIE86899.1 - 2.3e-06 27.5 15.3 0.056 13.3 0.2 6.1 5 2 1 7 7 7 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 EIE86899.1 - 1.3e-05 25.5 3.2 1.1 9.7 0.0 5.8 5 0 0 5 5 5 1 Vacuolar 14 Fab1-binding region Arm PF00514.18 EIE86899.1 - 0.00028 20.5 8.4 3.1 7.7 0.0 6.6 8 0 0 8 8 7 2 Armadillo/beta-catenin-like repeat UME PF08064.8 EIE86899.1 - 0.00049 20.0 13.4 3.8 7.5 0.0 7.0 7 2 1 8 8 8 1 UME (NUC010) domain DUF1546 PF07571.8 EIE86899.1 - 0.0036 17.3 0.8 11 6.1 0.0 4.5 3 1 1 4 4 4 1 Protein of unknown function (DUF1546) V-ATPase_H_C PF11698.3 EIE86899.1 - 0.0036 17.1 3.7 2.7 7.9 0.2 5.5 6 0 0 6 6 6 1 V-ATPase subunit H CLASP_N PF12348.3 EIE86899.1 - 0.021 14.1 16.3 0.06 12.6 0.2 6.1 5 2 1 7 7 7 0 CLASP N terminal DRIM PF07539.7 EIE86899.1 - 0.03 13.7 4.4 1.1 8.6 0.0 4.3 4 0 0 4 4 4 0 Down-regulated in metastasis DUF2457 PF10446.4 EIE86899.1 - 3.3 6.3 13.5 5.1 5.7 9.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RGS PF00615.14 EIE86901.1 - 4.2e-17 62.3 3.6 4.2e-17 62.3 2.5 2.0 2 0 0 2 2 2 1 Regulator of G protein signaling domain RGS-like PF09128.6 EIE86901.1 - 0.001 18.6 0.4 0.0017 17.8 0.3 1.6 1 1 0 1 1 1 1 Regulator of G protein signalling-like domain SRF-TF PF00319.13 EIE86903.1 - 2.4e-23 81.0 0.2 3.4e-23 80.6 0.2 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) ATG22 PF11700.3 EIE86903.1 - 0.0052 15.3 0.0 0.0056 15.2 0.0 1.1 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like CDC45 PF02724.9 EIE86903.1 - 0.046 11.7 0.4 0.054 11.5 0.3 1.1 1 0 0 1 1 1 0 CDC45-like protein MRP-S25 PF13741.1 EIE86903.1 - 0.079 12.4 0.9 0.12 11.8 0.6 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein S25 DUF1110 PF06533.7 EIE86905.1 - 0.0026 17.6 3.0 0.18 11.6 0.1 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF1110) BRE1 PF08647.6 EIE86905.1 - 0.0039 17.1 12.9 0.0039 17.1 9.0 6.7 5 3 2 7 7 7 1 BRE1 E3 ubiquitin ligase DUF963 PF06131.6 EIE86905.1 - 0.0046 16.2 8.5 0.011 14.9 5.9 1.6 1 0 0 1 1 1 1 Schizosaccharomyces pombe repeat of unknown function (DUF963) T2SF PF00482.18 EIE86905.1 - 0.22 11.4 1.1 0.65 9.9 0.3 2.2 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F DUF1279 PF06916.8 EIE86907.1 - 1.3e-15 57.4 0.0 1.9e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) LRR_8 PF13855.1 EIE86908.1 - 1.9e-22 78.7 30.0 1.8e-07 30.7 0.9 4.3 2 1 1 4 4 4 4 Leucine rich repeat LRR_4 PF12799.2 EIE86908.1 - 5.8e-21 73.6 41.3 1.5e-06 27.7 2.1 5.9 3 2 3 7 7 7 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EIE86908.1 - 3.3e-15 53.7 37.6 0.0077 16.1 0.4 10.6 10 0 0 10 10 10 5 Leucine Rich Repeat LRR_6 PF13516.1 EIE86908.1 - 3.7e-06 26.4 37.9 0.0065 16.4 0.7 8.9 9 1 1 10 10 10 2 Leucine Rich repeat LRR_7 PF13504.1 EIE86908.1 - 0.0029 17.5 25.6 0.39 11.1 0.1 8.5 10 0 0 10 10 10 2 Leucine rich repeat LRRNT_2 PF08263.7 EIE86908.1 - 0.0042 17.0 9.5 0.011 15.6 6.6 1.7 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain Pentapeptide PF00805.17 EIE86908.1 - 1.9 7.8 5.9 23 4.3 0.1 4.1 5 0 0 5 5 5 0 Pentapeptide repeats (8 copies) C2 PF00168.25 EIE86909.1 - 1.5e-12 47.1 0.1 2.2e-12 46.6 0.1 1.3 1 0 0 1 1 1 1 C2 domain Aminotran_1_2 PF00155.16 EIE86910.1 - 4.4e-62 210.1 0.0 5.7e-62 209.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EIE86910.1 - 4.5e-07 29.3 0.0 6.6e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 EIE86910.1 - 4.6e-06 25.1 0.0 7.7e-06 24.4 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EIE86910.1 - 0.00089 18.3 0.0 0.0013 17.8 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 EIE86910.1 - 0.028 13.1 0.0 0.04 12.6 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Asp-B-Hydro_N PF05279.6 EIE86911.1 - 0.0073 16.1 7.6 0.0082 16.0 5.3 1.1 1 0 0 1 1 1 1 Aspartyl beta-hydroxylase N-terminal region DUF1690 PF07956.6 EIE86911.1 - 0.044 13.7 2.1 0.052 13.5 1.5 1.2 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) Endotoxin_N PF03945.9 EIE86911.1 - 0.1 11.9 0.5 0.11 11.9 0.3 1.1 1 0 0 1 1 1 0 delta endotoxin, N-terminal domain DUF904 PF06005.7 EIE86911.1 - 1.3 9.3 10.4 3 8.1 7.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF904) DUF883 PF05957.8 EIE86911.1 - 1.3 9.4 4.1 1.5 9.2 2.0 1.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) RGS PF00615.14 EIE86912.1 - 2 8.5 6.0 5.3 7.1 2.1 3.0 2 2 0 2 2 2 0 Regulator of G protein signaling domain Cyclin PF08613.6 EIE86913.1 - 3.5e-17 63.1 0.3 5.8e-17 62.4 0.2 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EIE86913.1 - 0.0002 20.9 0.3 0.051 13.1 0.0 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain Peptidase_A2B PF12384.3 EIE86913.1 - 0.078 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Ty3 transposon peptidase Chitin_synth_2 PF03142.10 EIE86914.1 - 3.6e-78 263.2 0.6 8e-56 189.5 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_tranf_2_3 PF13641.1 EIE86914.1 - 1e-05 25.4 0.0 0.00095 19.0 0.0 2.5 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 EIE86914.1 - 0.00013 21.6 0.0 0.0063 16.2 0.0 2.7 2 1 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.1 EIE86914.1 - 0.00098 18.8 5.4 0.0041 16.8 0.0 2.7 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 EIE86914.1 - 0.00099 18.8 0.0 0.36 10.4 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EIE86914.1 - 0.031 13.5 0.0 0.06 12.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 21 GATA PF00320.22 EIE86915.1 - 2.1e-05 23.7 4.4 3.6e-05 23.0 3.0 1.4 1 0 0 1 1 1 1 GATA zinc finger AFG1_ATPase PF03969.11 EIE86916.1 - 1.9e-108 362.5 1.7 8.9e-103 343.8 0.3 2.1 1 1 1 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.1 EIE86916.1 - 2.8e-05 24.2 0.1 0.011 15.6 0.0 2.6 1 1 1 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 EIE86916.1 - 0.00013 22.0 0.0 0.00038 20.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain Bac_DnaA PF00308.13 EIE86916.1 - 0.0028 17.3 1.6 0.044 13.4 0.1 2.8 3 1 0 3 3 3 1 Bacterial dnaA protein AAA PF00004.24 EIE86916.1 - 0.0031 17.6 0.1 0.015 15.5 0.0 2.2 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EIE86916.1 - 0.0033 17.3 0.0 0.0098 15.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EIE86916.1 - 0.0079 15.9 0.0 0.22 11.1 0.0 2.4 2 1 0 2 2 2 1 Archaeal ATPase PIF1 PF05970.9 EIE86916.1 - 0.13 11.2 0.1 0.34 9.8 0.0 1.6 2 0 0 2 2 2 0 PIF1-like helicase DDE_1 PF03184.14 EIE86917.1 - 0.032 13.3 0.0 0.047 12.8 0.0 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease DUF1847 PF08901.6 EIE86917.1 - 0.11 12.0 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1847) UPF0052 PF01933.13 EIE86919.1 - 0.047 13.0 0.0 0.05 12.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0052 7tm_1 PF00001.16 EIE86920.1 - 0.03 13.4 0.1 0.03 13.4 0.0 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DUF3420 PF11900.3 EIE86922.1 - 0.019 15.0 0.5 0.074 13.1 0.4 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3420) Catalase-rel PF06628.7 EIE86922.1 - 0.043 13.6 0.4 0.28 11.0 0.0 2.5 3 0 0 3 3 3 0 Catalase-related immune-responsive COMP PF11598.3 EIE86922.1 - 0.14 12.2 1.3 0.51 10.4 0.9 2.0 1 0 0 1 1 1 0 Cartilage oligomeric matrix protein 60KD_IMP PF02096.15 EIE86922.1 - 0.38 10.3 5.1 3.7 7.1 0.1 2.4 2 0 0 2 2 2 0 60Kd inner membrane protein CheZ PF04344.8 EIE86922.1 - 0.64 9.6 8.3 0.65 9.6 1.2 2.3 2 0 0 2 2 2 0 Chemotaxis phosphatase, CheZ HK97-gp10_like PF04883.7 EIE86922.1 - 5.7 7.9 9.7 0.37 11.7 1.2 2.6 2 1 0 2 2 2 0 Bacteriophage HK97-gp10, putative tail-component Vfa1 PF08432.5 EIE86922.1 - 7.3 6.5 27.6 0.16 11.9 9.0 2.1 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DUF3608 PF12257.3 EIE86923.1 - 0.021 13.7 0.0 0.034 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3608) DUF964 PF06133.6 EIE86923.1 - 0.095 12.7 4.1 0.18 11.8 2.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF964) AIF_C PF14721.1 EIE86923.1 - 0.29 11.3 2.6 0.54 10.5 0.1 2.0 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DDOST_48kD PF03345.9 EIE86924.1 - 3.1e-110 368.6 8.9 4.9e-86 288.8 1.3 2.0 1 1 1 2 2 2 2 Oligosaccharyltransferase 48 kDa subunit beta Dopey_N PF04118.9 EIE86924.1 - 0.068 11.9 0.1 0.19 10.4 0.0 1.7 2 0 0 2 2 2 0 Dopey, N-terminal Thioredoxin PF00085.15 EIE86925.1 - 0.00021 20.9 0.1 0.00034 20.2 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.11 EIE86925.1 - 0.018 13.7 0.6 0.03 13.0 0.4 1.3 1 0 0 1 1 1 0 Phosducin tRNA-synt_2d PF01409.15 EIE86926.1 - 1.1e-89 299.9 0.1 1.5e-89 299.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.15 EIE86926.1 - 5.3e-07 28.7 2.7 6.9e-05 21.7 0.0 3.5 4 0 0 4 4 4 2 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 EIE86926.1 - 5.1e-06 26.1 0.0 1.1e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) DUF2183 PF09949.4 EIE86927.1 - 3.8e-30 103.7 0.0 1e-29 102.4 0.0 1.8 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) LNS2 PF08235.8 EIE86927.1 - 0.0005 19.6 0.0 0.00088 18.8 0.0 1.4 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Plectin PF00681.15 EIE86927.1 - 0.065 12.7 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Plectin repeat Acyl_CoA_thio PF02551.10 EIE86928.1 - 4.8e-31 107.1 0.1 1.1e-27 96.2 0.0 2.2 2 0 0 2 2 2 2 Acyl-CoA thioesterase 4HBT_3 PF13622.1 EIE86928.1 - 8.1e-31 107.6 0.0 1e-30 107.3 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Baculo_LEF-10 PF07206.6 EIE86929.1 - 0.12 12.0 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Baculovirus late expression factor 10 (LEF-10) SUR7 PF06687.7 EIE86930.1 - 9.5e-14 51.4 11.3 1.6e-13 50.7 7.8 1.4 1 1 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 EIE86930.1 - 0.012 15.2 6.6 0.034 13.8 4.5 1.7 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF996 PF06195.8 EIE86930.1 - 0.066 13.1 5.2 0.064 13.2 2.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF996) DUF4282 PF14110.1 EIE86930.1 - 1.3 9.2 9.2 0.81 9.9 4.7 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4282) zf-C2H2 PF00096.21 EIE86932.1 - 9.1e-16 57.1 24.8 2.4e-07 30.7 1.4 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIE86932.1 - 3e-12 46.1 17.6 6.8e-09 35.5 0.8 4.2 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EIE86932.1 - 3.7e-11 42.5 21.9 0.0005 20.2 0.7 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EIE86932.1 - 0.0034 17.4 14.6 1 9.5 0.4 4.0 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding DUF2890 PF11081.3 EIE86932.1 - 0.0043 17.1 2.5 0.006 16.6 1.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2890) zf-met PF12874.2 EIE86932.1 - 0.061 13.5 14.0 6.3 7.1 0.0 5.3 5 0 0 5 5 5 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EIE86932.1 - 0.075 12.9 10.6 5.8 6.9 0.2 3.9 4 0 0 4 4 4 0 C2H2-type zinc finger Zn_Tnp_IS1595 PF12760.2 EIE86932.1 - 0.16 11.8 9.8 0.81 9.5 1.6 2.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-C2HC_2 PF13913.1 EIE86932.1 - 0.37 10.5 14.6 0.46 10.2 0.8 3.6 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Mu-like_Com PF10122.4 EIE86932.1 - 0.54 9.3 4.9 1 8.4 0.4 2.5 2 0 0 2 2 2 0 Mu-like prophage protein Com Zn-ribbon_8 PF09723.5 EIE86932.1 - 1 9.3 7.7 8.9 6.3 0.3 3.2 2 1 1 3 3 3 0 Zinc ribbon domain C1_4 PF07975.7 EIE86932.1 - 1.1 9.3 5.3 1.6 8.8 0.2 2.5 1 1 1 2 2 2 0 TFIIH C1-like domain Zn_ribbon_recom PF13408.1 EIE86932.1 - 2.5 8.4 10.4 59 4.0 7.2 2.7 1 1 0 1 1 1 0 Recombinase zinc beta ribbon domain zf-BED PF02892.10 EIE86932.1 - 8.6 6.2 20.1 1.8 8.4 2.3 4.2 4 0 0 4 4 4 0 BED zinc finger Pkinase PF00069.20 EIE86934.1 - 5.6e-52 176.4 0.0 9.4e-52 175.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE86934.1 - 3.6e-22 78.6 0.0 5.6e-22 78.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE86934.1 - 3.9e-05 22.7 1.3 0.0082 15.1 0.0 2.2 1 1 1 2 2 2 2 Kinase-like zf-DNL PF05180.7 EIE86935.1 - 5.2e-31 106.1 2.4 7.3e-31 105.6 0.3 2.0 2 0 0 2 2 2 1 DNL zinc finger Elf1 PF05129.8 EIE86935.1 - 0.0012 18.4 0.5 0.0027 17.3 0.3 1.5 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like DUF4606 PF15379.1 EIE86935.1 - 0.0022 18.0 1.0 0.012 15.6 0.1 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF4606) UPF0167 PF03691.9 EIE86935.1 - 0.097 12.0 1.5 0.14 11.5 0.2 1.7 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0167) IGPD PF00475.13 EIE86935.1 - 0.11 12.3 0.1 0.34 10.7 0.0 1.7 1 1 1 2 2 2 0 Imidazoleglycerol-phosphate dehydratase zinc_ribbon_4 PF13717.1 EIE86935.1 - 0.24 11.1 0.0 0.24 11.1 0.0 2.6 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EIE86935.1 - 0.25 10.9 0.0 0.25 10.9 0.0 2.6 3 0 0 3 3 3 0 zinc-ribbon domain DUF2628 PF10947.3 EIE86936.1 - 5.9 6.7 10.9 2.7 7.8 3.8 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2628) DUF3040 PF11239.3 EIE86936.1 - 7.2 6.7 8.5 0.63 10.1 1.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Orn_Arg_deC_N PF02784.11 EIE86937.1 - 2.3e-79 266.1 0.0 2.9e-79 265.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 EIE86937.1 - 3.5e-33 113.7 0.1 6e-33 113.0 0.1 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Hist_deacetyl PF00850.14 EIE86938.1 - 3.3e-85 286.1 0.1 6.8e-85 285.0 0.0 1.5 1 0 0 1 1 1 1 Histone deacetylase domain Ras PF00071.17 EIE86939.1 - 9.2e-58 194.1 0.1 1.1e-57 193.9 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIE86939.1 - 9.1e-18 64.8 0.0 1.5e-17 64.1 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIE86939.1 - 6.9e-13 48.2 0.0 8.6e-13 47.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EIE86939.1 - 1.3e-06 27.6 0.0 1.7e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EIE86939.1 - 2.3e-06 27.5 0.0 3.3e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EIE86939.1 - 3.4e-05 23.3 0.0 0.00079 18.9 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EIE86939.1 - 0.00046 20.3 0.0 0.00093 19.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EIE86939.1 - 0.00091 18.4 0.1 0.0021 17.2 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 cobW PF02492.14 EIE86939.1 - 0.0013 18.1 0.0 0.0023 17.3 0.0 1.6 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.10 EIE86939.1 - 0.0019 17.9 0.0 0.0033 17.1 0.0 1.4 1 0 0 1 1 1 1 NTPase PduV-EutP PF10662.4 EIE86939.1 - 0.0021 17.5 0.2 0.092 12.2 0.0 2.1 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.1 EIE86939.1 - 0.0049 16.4 0.1 0.0096 15.5 0.1 1.4 1 0 0 1 1 1 1 AAA domain Septin PF00735.13 EIE86939.1 - 0.005 15.8 0.6 0.015 14.3 0.0 2.0 3 0 0 3 3 3 1 Septin Arch_ATPase PF01637.13 EIE86939.1 - 0.0056 16.4 0.2 0.01 15.5 0.0 1.4 2 0 0 2 2 2 1 Archaeal ATPase MobB PF03205.9 EIE86939.1 - 0.0079 15.8 0.1 0.021 14.5 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 EIE86939.1 - 0.013 14.9 0.2 0.038 13.4 0.1 1.7 1 1 0 2 2 2 0 AAA-like domain ATP_bind_1 PF03029.12 EIE86939.1 - 0.014 14.9 0.3 0.63 9.5 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_16 PF13191.1 EIE86939.1 - 0.015 15.2 0.0 0.031 14.2 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain SRPRB PF09439.5 EIE86939.1 - 0.02 14.1 0.0 0.035 13.3 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_5 PF07728.9 EIE86939.1 - 0.035 13.8 0.0 0.083 12.6 0.0 1.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NACHT PF05729.7 EIE86939.1 - 0.057 13.0 0.0 0.096 12.3 0.0 1.3 1 0 0 1 1 1 0 NACHT domain FeoB_N PF02421.13 EIE86939.1 - 0.075 12.3 0.0 0.88 8.8 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_14 PF13173.1 EIE86939.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain FH2 PF02181.18 EIE86940.1 - 1.3e-60 205.2 21.2 3.1e-57 194.1 11.7 4.3 2 1 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.8 EIE86940.1 - 2.6e-30 105.1 5.0 1.8e-29 102.4 0.2 3.6 2 1 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 EIE86940.1 - 3.2e-28 98.4 0.3 1.2e-27 96.5 0.0 2.2 2 0 0 2 2 2 1 Diaphanous FH3 Domain HALZ PF02183.13 EIE86940.1 - 0.0062 16.2 0.6 0.0062 16.2 0.4 3.2 3 0 0 3 3 3 1 Homeobox associated leucine zipper Transformer PF06495.6 EIE86940.1 - 0.3 10.9 7.3 0.7 9.7 5.1 1.5 1 0 0 1 1 1 0 Fruit fly transformer protein Cortex-I_coil PF09304.5 EIE86940.1 - 2.6 8.1 18.7 0.086 12.8 4.9 3.5 3 0 0 3 3 3 0 Cortexillin I, coiled coil RAI16-like PF10257.4 EIE86941.1 - 1.8e-62 211.3 2.1 3.1e-62 210.5 1.4 1.4 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein DUF2935 PF11155.3 EIE86941.1 - 0.34 11.0 3.1 0.75 9.8 1.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2935) SNAP PF14938.1 EIE86942.1 - 6.1e-93 311.0 14.4 6.9e-93 310.8 10.0 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_11 PF13414.1 EIE86942.1 - 2.1e-07 30.4 11.3 1.8e-05 24.2 1.0 3.5 2 1 1 3 3 3 3 TPR repeat TPR_12 PF13424.1 EIE86942.1 - 5.5e-06 26.2 8.1 0.0038 17.1 0.4 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat PhageMin_Tail PF10145.4 EIE86942.1 - 0.0029 17.2 1.3 0.055 13.1 1.0 2.1 1 1 1 2 2 2 2 Phage-related minor tail protein NSF PF02071.15 EIE86942.1 - 0.0044 17.2 17.5 0.64 10.8 0.1 7.2 7 1 0 7 7 7 2 Aromatic-di-Alanine (AdAR) repeat DHC_N1 PF08385.7 EIE86942.1 - 0.019 13.3 0.6 1.5 7.1 0.1 2.1 2 0 0 2 2 2 0 Dynein heavy chain, N-terminal region 1 MscS_porin PF12795.2 EIE86942.1 - 0.028 13.7 0.3 0.053 12.8 0.2 1.5 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Lipoprotein_2 PF00921.12 EIE86942.1 - 0.042 13.8 1.2 0.073 13.0 0.8 1.4 1 0 0 1 1 1 0 Borrelia lipoprotein TPR_2 PF07719.12 EIE86942.1 - 0.073 13.0 14.9 9.1 6.4 0.3 5.7 4 1 2 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.1 EIE86942.1 - 0.097 13.1 12.7 1.1 9.8 0.1 5.1 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 EIE86942.1 - 0.11 12.3 6.4 12 5.9 0.0 5.3 2 1 1 3 3 3 0 Tetratricopeptide repeat YdjO PF14169.1 EIE86942.1 - 0.12 11.8 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Cold-inducible protein YdjO TPR_14 PF13428.1 EIE86942.1 - 0.26 12.0 9.3 31 5.5 0.2 4.8 1 1 4 5 5 5 0 Tetratricopeptide repeat Spc7 PF08317.6 EIE86943.1 - 9.7e-05 21.1 1.0 0.0001 21.0 0.7 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein Apolipoprotein PF01442.13 EIE86943.1 - 0.0032 16.9 3.1 0.0038 16.7 2.2 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Filament PF00038.16 EIE86943.1 - 0.0091 15.4 1.9 0.011 15.2 1.3 1.1 1 0 0 1 1 1 1 Intermediate filament protein Exonuc_VII_L PF02601.10 EIE86943.1 - 0.011 15.0 1.1 0.01 15.0 0.7 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Snf7 PF03357.16 EIE86943.1 - 0.015 14.7 0.4 0.015 14.7 0.3 1.7 1 1 1 2 2 2 0 Snf7 Macoilin PF09726.4 EIE86943.1 - 0.022 13.0 1.9 0.023 13.0 1.3 1.0 1 0 0 1 1 1 0 Transmembrane protein Tropomyosin PF00261.15 EIE86943.1 - 0.031 13.3 5.4 0.037 13.1 3.7 1.1 1 0 0 1 1 1 0 Tropomyosin HrpF PF06266.7 EIE86943.1 - 0.032 14.3 0.8 0.054 13.6 0.5 1.3 1 0 0 1 1 1 0 HrpF protein Prefoldin_2 PF01920.15 EIE86943.1 - 0.045 13.5 0.7 0.045 13.5 0.5 1.9 2 0 0 2 2 2 0 Prefoldin subunit DUF883 PF05957.8 EIE86943.1 - 0.046 14.1 2.7 0.046 14.1 1.8 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Myosin_tail_1 PF01576.14 EIE86943.1 - 0.07 10.8 5.0 0.083 10.6 3.5 1.1 1 0 0 1 1 1 0 Myosin tail DUF4071 PF13281.1 EIE86943.1 - 0.071 11.9 0.1 0.074 11.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4071) RmuC PF02646.11 EIE86943.1 - 0.079 11.7 2.7 0.12 11.2 1.9 1.3 1 0 0 1 1 1 0 RmuC family Mnd1 PF03962.10 EIE86943.1 - 0.1 12.2 2.7 0.12 12.0 1.9 1.1 1 0 0 1 1 1 0 Mnd1 family DUF4618 PF15397.1 EIE86943.1 - 0.11 11.8 1.4 0.13 11.6 1.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) WXG100 PF06013.7 EIE86943.1 - 0.11 12.4 1.9 0.25 11.3 0.2 2.1 1 1 0 1 1 1 0 Proteins of 100 residues with WXG GCN5L1 PF06320.8 EIE86943.1 - 0.12 12.2 1.6 0.15 11.9 1.1 1.1 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) DUF4337 PF14235.1 EIE86943.1 - 0.13 12.1 2.0 0.16 11.7 1.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) ApoO PF09769.4 EIE86943.1 - 0.15 11.7 0.6 0.32 10.7 0.3 1.5 1 1 1 2 2 2 0 Apolipoprotein O IMD PF08397.6 EIE86943.1 - 0.16 11.2 2.1 0.22 10.7 1.4 1.3 1 1 0 1 1 1 0 IRSp53/MIM homology domain LemA PF04011.7 EIE86943.1 - 0.18 10.9 2.0 0.26 10.3 1.4 1.2 1 0 0 1 1 1 0 LemA family Tropomyosin_1 PF12718.2 EIE86943.1 - 0.18 11.6 5.6 0.27 11.0 3.9 1.2 1 0 0 1 1 1 0 Tropomyosin like ERM PF00769.14 EIE86943.1 - 0.2 11.1 5.6 0.29 10.6 3.9 1.3 1 1 0 1 1 1 0 Ezrin/radixin/moesin family DUF3584 PF12128.3 EIE86943.1 - 0.22 8.8 4.2 0.24 8.6 2.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF3560 PF12083.3 EIE86943.1 - 0.23 11.5 4.1 0.3 11.1 2.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3560) FUN14 PF04930.10 EIE86943.1 - 0.23 11.7 1.3 2.2 8.6 0.9 2.0 1 1 0 1 1 1 0 FUN14 family GreA_GreB_N PF03449.10 EIE86943.1 - 0.24 11.4 2.6 0.2 11.7 0.4 1.8 1 1 1 2 2 2 0 Transcription elongation factor, N-terminal Mitofilin PF09731.4 EIE86943.1 - 0.27 9.8 5.6 0.35 9.4 3.9 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein MT0933_antitox PF14013.1 EIE86943.1 - 0.3 11.2 3.4 8.3 6.5 2.3 2.4 1 1 0 1 1 1 0 MT0933-like antitoxin protein DUF4407 PF14362.1 EIE86943.1 - 0.36 9.7 5.2 0.48 9.3 3.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MtrG PF04210.8 EIE86943.1 - 0.38 10.4 2.1 3.2 7.4 0.3 2.7 1 1 1 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G APG6 PF04111.7 EIE86943.1 - 0.57 9.1 3.0 0.63 9.0 2.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4363 PF14276.1 EIE86943.1 - 0.87 9.3 3.5 3.2 7.4 0.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4363) GrpE PF01025.14 EIE86943.1 - 0.97 8.9 5.8 2.7 7.4 4.0 1.7 1 1 0 1 1 1 0 GrpE DUF1542 PF07564.6 EIE86943.1 - 3 7.9 9.4 7 6.7 1.0 2.3 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1542) DUF4200 PF13863.1 EIE86943.1 - 3.6 7.5 7.6 7 6.6 5.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) ATP-synt_B PF00430.13 EIE86943.1 - 5.7 6.7 9.1 10 5.9 6.3 1.5 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) Cyclin PF08613.6 EIE86944.1 - 4.4e-20 72.5 0.2 6.9e-20 71.9 0.2 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EIE86944.1 - 5.9e-06 25.8 0.8 8.9e-06 25.2 0.1 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain zf-AN1 PF01428.11 EIE86945.1 - 8.5e-08 31.9 12.1 8.5e-08 31.9 8.4 1.9 2 0 0 2 2 2 1 AN1-like Zinc finger Spc7 PF08317.6 EIE86945.1 - 0.54 8.8 5.1 0.86 8.2 3.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein NAD_binding_10 PF13460.1 EIE86946.1 - 1.4e-22 80.5 0.1 2e-22 80.0 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EIE86946.1 - 7e-17 61.4 0.0 9.7e-17 60.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 EIE86946.1 - 1.6e-10 40.2 0.1 5e-10 38.5 0.0 1.8 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EIE86946.1 - 3.9e-10 39.5 0.0 8.4e-10 38.4 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 EIE86946.1 - 2.2e-08 33.5 0.0 3.2e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase RmlD_sub_bind PF04321.12 EIE86946.1 - 9.8e-07 27.9 0.0 0.011 14.6 0.0 2.9 2 1 0 2 2 2 2 RmlD substrate binding domain NAD_binding_4 PF07993.7 EIE86946.1 - 1.2e-06 27.6 0.1 0.014 14.2 0.0 2.7 1 1 1 2 2 2 2 Male sterility protein adh_short PF00106.20 EIE86946.1 - 0.00015 21.6 0.0 0.0024 17.8 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase F420_oxidored PF03807.12 EIE86946.1 - 0.0062 16.9 0.0 0.037 14.4 0.0 2.2 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent DAO PF01266.19 EIE86946.1 - 0.017 14.0 0.1 0.026 13.4 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase DapB_N PF01113.15 EIE86946.1 - 0.019 14.8 0.0 0.04 13.8 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Polysacc_synt_2 PF02719.10 EIE86946.1 - 0.025 13.5 0.0 0.14 11.0 0.0 2.0 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_2 PF03446.10 EIE86946.1 - 0.026 14.3 0.0 0.058 13.2 0.0 1.6 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase KR PF08659.5 EIE86946.1 - 0.059 13.0 0.0 0.39 10.3 0.0 2.0 2 0 0 2 2 2 0 KR domain SNARE PF05739.14 EIE86947.1 - 1.1e-14 53.7 1.3 2.8e-14 52.5 0.9 1.7 1 0 0 1 1 1 1 SNARE domain VitD-bind_III PF09164.5 EIE86947.1 - 0.047 13.3 0.0 0.13 11.9 0.0 1.8 1 0 0 1 1 1 0 Vitamin D binding protein, domain III Ras PF00071.17 EIE86949.1 - 1e-42 145.2 0.0 1.3e-42 144.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIE86949.1 - 1.1e-17 64.6 0.0 4.3e-17 62.7 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EIE86949.1 - 1.5e-10 40.6 0.0 2.1e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EIE86949.1 - 6.8e-07 28.6 0.0 1.3e-06 27.7 0.0 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EIE86949.1 - 0.00043 19.7 0.1 0.024 14.0 0.0 2.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.12 EIE86949.1 - 0.0023 17.5 0.0 1.8 8.0 0.0 2.2 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein PduV-EutP PF10662.4 EIE86949.1 - 0.0074 15.7 0.1 0.22 10.9 0.0 2.4 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 EIE86949.1 - 0.0081 15.8 0.1 0.018 14.7 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 EIE86949.1 - 0.0099 15.8 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EIE86949.1 - 0.011 15.6 0.5 0.17 11.8 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 EIE86949.1 - 0.026 14.6 0.1 0.058 13.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 EIE86949.1 - 0.043 13.2 0.0 0.77 9.1 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_10 PF12846.2 EIE86949.1 - 0.063 12.7 0.1 0.24 10.8 0.1 1.8 1 1 0 1 1 1 0 AAA-like domain AAA_32 PF13654.1 EIE86949.1 - 0.091 11.4 0.1 0.091 11.4 0.1 1.8 2 0 0 2 2 2 0 AAA domain SRPRB PF09439.5 EIE86949.1 - 0.12 11.5 0.8 0.46 9.6 0.0 1.9 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Lipase_GDSL_2 PF13472.1 EIE86950.1 - 1.5e-05 25.1 0.0 2.8e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_3 PF14606.1 EIE86950.1 - 0.00059 19.6 0.0 0.023 14.4 0.0 2.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EIE86950.1 - 0.017 14.9 0.2 0.095 12.5 0.1 2.0 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase ATP-synt_S1 PF05827.7 EIE86951.1 - 4.7e-16 58.9 4.3 9.8e-16 57.8 3.0 1.5 1 1 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Phage_int_SAM_5 PF13102.1 EIE86952.1 - 0.039 13.9 0.2 0.057 13.4 0.2 1.4 1 1 0 1 1 1 0 Phage integrase SAM-like domain GIDA PF01134.17 EIE86953.1 - 1.7e-128 428.8 0.1 3.7e-128 427.7 0.1 1.5 1 1 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 EIE86953.1 - 2.1e-21 75.7 0.5 7.7e-21 73.9 0.1 2.2 3 0 0 3 3 3 1 GidA associated domain 3 FAD_oxidored PF12831.2 EIE86953.1 - 1.8e-06 27.3 0.1 2.8e-06 26.6 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EIE86953.1 - 0.0001 22.2 0.6 0.00025 20.9 0.4 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EIE86953.1 - 0.00018 20.4 1.3 0.00038 19.4 0.9 1.5 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EIE86953.1 - 0.00033 19.2 1.0 0.011 14.2 0.4 2.3 2 0 0 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.16 EIE86953.1 - 0.014 15.0 0.2 0.035 13.6 0.1 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 EIE86953.1 - 0.07 12.2 0.2 0.15 11.1 0.1 1.5 1 0 0 1 1 1 0 Thi4 family HpcH_HpaI PF03328.9 EIE86953.1 - 0.076 11.8 0.0 0.14 11.0 0.0 1.4 1 0 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family SPRY PF00622.23 EIE86954.1 - 1.3e-17 63.9 0.2 2e-17 63.4 0.1 1.3 1 0 0 1 1 1 1 SPRY domain Ten_N PF06484.7 EIE86956.1 - 0.01 14.9 0.7 0.012 14.7 0.5 1.0 1 0 0 1 1 1 0 Teneurin Intracellular Region TFIIB PF00382.14 EIE86957.1 - 2.5e-28 97.6 1.2 1.3e-24 85.7 0.4 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 EIE86957.1 - 1.4e-15 56.3 0.5 2.3e-15 55.5 0.4 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.18 EIE86957.1 - 0.15 11.6 0.7 0.31 10.6 0.4 1.5 1 1 0 1 1 1 0 Cyclin, N-terminal domain zf-CCHC PF00098.18 EIE86959.1 - 1.8e-47 157.0 53.9 6.3e-08 32.1 0.4 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.1 EIE86959.1 - 9.4e-10 38.0 46.6 0.05 13.2 0.5 7.2 7 0 0 7 7 7 6 Zinc knuckle zf-CCHC_3 PF13917.1 EIE86959.1 - 2.9e-06 26.9 47.6 0.054 13.2 0.1 7.0 1 1 5 6 6 6 4 Zinc knuckle CDC45 PF02724.9 EIE86959.1 - 6.1 4.7 6.5 7.6 4.4 4.5 1.1 1 0 0 1 1 1 0 CDC45-like protein UPF0016 PF01169.14 EIE86960.1 - 4.9e-42 141.9 16.9 5.6e-22 77.6 5.2 2.1 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 TauE PF01925.14 EIE86960.1 - 1.4e-05 24.6 5.5 0.02 14.3 0.0 2.1 2 0 0 2 2 2 2 Sulfite exporter TauE/SafE Gate PF07670.9 EIE86960.1 - 0.029 14.2 0.6 0.068 13.0 0.4 1.7 1 1 0 1 1 1 0 Nucleoside recognition DUF204 PF02659.10 EIE86960.1 - 3.8 7.6 11.5 6.6 6.9 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF FKBP_C PF00254.23 EIE86964.1 - 1.8e-34 117.6 0.0 7.4e-34 115.6 0.0 1.9 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase Sugar_tr PF00083.19 EIE86965.1 - 2.4e-89 299.9 35.3 2.8e-52 177.7 5.4 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EIE86965.1 - 3.3e-23 81.9 36.2 1.2e-17 63.7 15.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Linker_histone PF00538.14 EIE86966.1 - 6.4e-22 77.4 0.2 1.4e-21 76.3 0.2 1.6 1 0 0 1 1 1 1 linker histone H1 and H5 family DUF126 PF01989.11 EIE86966.1 - 0.075 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF126 DUF4553 PF15090.1 EIE86966.1 - 0.44 9.4 39.6 0.5 9.3 27.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4553) Rib_5-P_isom_A PF06026.9 EIE86967.1 - 5.3e-57 191.8 0.1 8e-57 191.3 0.0 1.3 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) Zn_clus PF00172.13 EIE86967.1 - 0.0033 17.2 14.0 0.0065 16.3 9.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DeoRC PF00455.17 EIE86967.1 - 0.11 12.1 0.0 1.5 8.4 0.0 2.5 2 1 1 3 3 3 0 DeoR C terminal sensor domain RRM_1 PF00076.17 EIE86968.1 - 9.8e-29 98.8 0.6 2.2e-09 36.8 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE86968.1 - 2.2e-18 66.0 1.0 3.7e-05 23.6 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE86968.1 - 7.8e-06 25.6 0.1 1.4 8.7 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EIE86968.1 - 0.0034 17.1 0.1 1 9.2 0.0 2.5 2 1 0 2 2 2 2 RNA binding motif DUF2922 PF11148.3 EIE86968.1 - 0.061 12.9 0.2 0.86 9.3 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2922) Pkinase PF00069.20 EIE86969.1 - 2.4e-68 230.1 0.0 3.7e-68 229.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE86969.1 - 3.4e-34 118.1 0.0 5.5e-34 117.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE86969.1 - 0.00028 19.9 0.0 0.0007 18.6 0.0 1.6 1 1 0 1 1 1 1 Kinase-like TPR_10 PF13374.1 EIE86970.1 - 0.00024 20.9 1.0 0.67 9.9 0.2 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EIE86970.1 - 0.086 12.7 9.0 1.1 9.2 0.2 3.6 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.1 EIE86970.1 - 0.11 12.1 7.5 0.06 12.9 0.6 3.2 3 0 0 3 3 3 0 TPR repeat TPR_1 PF00515.23 EIE86970.1 - 0.34 10.6 8.2 4.1 7.1 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 EIE86970.1 - 6.3 6.9 10.6 1.5 8.8 0.3 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Ribosomal_S8e PF01201.17 EIE86971.1 - 4.1e-50 169.3 0.9 4.9e-50 169.0 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e Polysacc_deac_1 PF01522.16 EIE86973.1 - 6.5e-27 93.6 0.0 1.1e-26 92.9 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DDE_3 PF13358.1 EIE86974.1 - 8.5e-20 70.9 0.0 1.7e-19 69.9 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 EIE86974.1 - 7.8e-08 32.4 0.0 3.4e-07 30.3 0.0 1.9 1 1 1 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.1 EIE86974.1 - 3.9e-06 27.5 0.0 2.9e-05 24.7 0.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.1 EIE86974.1 - 9.1e-06 25.5 0.5 3e-05 23.9 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.1 EIE86974.1 - 0.0036 16.9 0.0 0.01 15.4 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_1 PF01527.15 EIE86974.1 - 0.0038 17.1 0.8 0.0073 16.2 0.6 1.4 1 0 0 1 1 1 1 Transposase DUF1804 PF08822.6 EIE86974.1 - 0.086 12.5 0.1 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1804) RVT_1 PF00078.22 EIE86975.1 - 1.8e-33 115.7 0.0 3.4e-33 114.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EIE86975.1 - 1.1e-10 41.1 0.8 1.1e-10 41.1 0.6 2.2 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EIE86975.1 - 2.6e-10 40.6 1.4 6.7e-10 39.3 0.9 1.7 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-CCHC PF00098.18 EIE86975.1 - 1.6e-05 24.5 9.0 0.002 17.9 0.4 2.6 2 0 0 2 2 2 2 Zinc knuckle RRM_6 PF14259.1 EIE86975.1 - 0.0024 17.8 0.0 0.62 10.0 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-CCHC_4 PF14392.1 EIE86975.1 - 0.0098 15.5 2.4 0.47 10.1 0.1 2.8 2 0 0 2 2 2 1 Zinc knuckle Egg_lysin PF01303.12 EIE86975.1 - 0.058 13.4 0.4 0.14 12.1 0.3 1.6 1 0 0 1 1 1 0 Egg lysin (Sperm-lysin) zf-CCHC_2 PF13696.1 EIE86975.1 - 0.18 11.2 6.4 0.17 11.4 1.6 2.4 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC_6 PF15288.1 EIE86975.1 - 6.6 6.4 11.5 7.5 6.3 1.0 2.7 1 1 1 2 2 2 0 Zinc knuckle Atg14 PF10186.4 EIE86976.1 - 0.00048 19.1 11.7 0.00048 19.1 8.1 1.8 2 0 0 2 2 2 1 UV radiation resistance protein and autophagy-related subunit 14 Tho2 PF11262.3 EIE86976.1 - 0.032 13.2 10.7 1.1 8.1 0.0 3.0 2 1 1 3 3 3 0 Transcription factor/nuclear export subunit protein 2 Surfac_D-trimer PF09006.6 EIE86976.1 - 4.9 6.9 7.4 2.2 8.0 0.3 3.2 3 0 0 3 3 3 0 Lung surfactant protein D coiled-coil trimerisation HEAT_2 PF13646.1 EIE86977.1 - 6.5e-19 67.9 12.9 6.3e-07 29.5 0.0 6.4 5 2 3 8 8 7 5 HEAT repeats HEAT PF02985.17 EIE86977.1 - 5.2e-16 57.2 9.7 0.0002 21.1 0.0 8.7 10 0 0 10 10 10 3 HEAT repeat HEAT_EZ PF13513.1 EIE86977.1 - 2.7e-14 53.1 11.1 2.2e-05 24.7 0.0 8.9 5 2 3 8 8 8 4 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EIE86977.1 - 4.1e-14 52.7 2.9 0.00039 20.7 0.0 7.0 4 3 5 9 9 8 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 EIE86977.1 - 8.4e-05 22.0 0.5 0.084 12.2 0.1 4.0 3 1 1 4 4 4 2 CLASP N terminal DUF3385 PF11865.3 EIE86977.1 - 0.0001 22.2 0.3 4.9 7.0 0.0 6.2 6 1 1 7 7 7 1 Domain of unknown function (DUF3385) RIX1 PF08167.7 EIE86977.1 - 0.00014 21.5 0.3 0.065 12.9 0.0 3.8 2 1 2 4 4 4 1 rRNA processing/ribosome biogenesis MMS19_C PF12460.3 EIE86977.1 - 0.0002 20.1 0.8 1.9 7.0 0.0 4.8 4 1 1 5 5 5 1 RNAPII transcription regulator C-terminal Arm PF00514.18 EIE86977.1 - 0.0014 18.3 0.6 1.5 8.7 0.0 4.8 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat DUF2454 PF10521.4 EIE86977.1 - 0.007 15.4 0.0 3.3 6.6 0.0 3.7 2 1 0 2 2 2 1 Protein of unknown function (DUF2454) Cnd1 PF12717.2 EIE86977.1 - 0.024 14.4 5.3 2.5 7.9 0.2 4.6 3 2 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 DUF2435 PF10363.4 EIE86977.1 - 0.029 14.2 0.6 0.23 11.3 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2435) IBN_N PF03810.14 EIE86977.1 - 0.096 12.6 0.6 0.57 10.1 0.2 2.6 2 0 0 2 2 1 0 Importin-beta N-terminal domain Ribosomal_L27 PF01016.14 EIE86978.1 - 2.1e-37 126.7 0.5 2.1e-37 126.7 0.3 1.8 2 0 0 2 2 2 1 Ribosomal L27 protein Pkinase PF00069.20 EIE86979.1 - 2.1e-13 50.0 0.0 1.2e-08 34.4 0.0 2.4 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIE86979.1 - 6.2e-08 32.0 0.0 6.2e-07 28.7 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase GerPC PF10737.4 EIE86979.1 - 0.065 13.0 0.2 0.38 10.5 0.1 2.0 2 0 0 2 2 2 0 Spore germination protein GerPC HalX PF08663.5 EIE86979.1 - 0.92 9.5 5.0 5.9 6.9 0.2 2.2 2 0 0 2 2 2 0 HalX domain Kelch_3 PF13415.1 EIE86980.1 - 1.2e-26 92.1 1.2 1.2e-07 31.6 0.0 4.2 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_5 PF13854.1 EIE86980.1 - 7.1e-25 86.5 1.9 2.8e-08 33.5 0.0 4.3 4 0 0 4 4 4 4 Kelch motif Kelch_4 PF13418.1 EIE86980.1 - 2.1e-23 81.8 2.6 3.1e-09 36.4 0.0 4.3 2 1 2 4 4 4 4 Galactose oxidase, central domain Kelch_1 PF01344.20 EIE86980.1 - 1.6e-22 78.7 2.3 1.3e-07 31.0 0.0 4.2 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.1 EIE86980.1 - 1.9e-22 78.4 3.8 7.2e-09 35.4 0.1 4.3 3 1 1 4 4 4 4 Kelch motif Kelch_2 PF07646.10 EIE86980.1 - 1.5e-19 68.9 2.1 5.9e-08 32.1 0.0 4.4 4 0 0 4 4 4 4 Kelch motif FUSC PF04632.7 EIE86980.1 - 6.5 5.0 5.7 9.4 4.5 4.0 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family Ribosomal_S13 PF00416.17 EIE86981.1 - 0.038 14.4 0.6 0.049 14.0 0.4 1.3 1 0 0 1 1 1 0 Ribosomal protein S13/S18 DUF3578 PF12102.3 EIE86982.1 - 0.083 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3578) DUF3450 PF11932.3 EIE86984.1 - 0.00035 19.9 1.3 0.0004 19.7 0.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) SlyX PF04102.7 EIE86984.1 - 0.0018 18.6 2.1 0.0029 17.9 1.5 1.4 1 0 0 1 1 1 1 SlyX Spc7 PF08317.6 EIE86984.1 - 0.0056 15.3 0.2 0.006 15.2 0.2 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein DivIVA PF05103.8 EIE86984.1 - 0.018 15.0 0.1 0.021 14.8 0.0 1.1 1 0 0 1 1 1 0 DivIVA protein RVT_2 PF07727.9 EIE86984.1 - 0.04 12.8 0.0 0.044 12.7 0.0 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Spc24 PF08286.6 EIE86984.1 - 0.2 11.3 3.1 0.26 10.9 2.1 1.4 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 DUF972 PF06156.8 EIE86984.1 - 0.29 11.5 1.6 0.36 11.1 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF972) O-FucT PF10250.4 EIE86985.1 - 2.6e-08 33.3 0.0 0.00014 21.0 0.1 3.2 2 1 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase XG_FTase PF03254.8 EIE86985.1 - 0.021 13.3 0.0 0.032 12.7 0.0 1.2 1 0 0 1 1 1 0 Xyloglucan fucosyltransferase Cornichon PF03311.9 EIE86986.1 - 1.7e-45 154.3 5.4 2.5e-45 153.7 3.2 1.6 2 0 0 2 2 2 1 Cornichon protein PCI_Csn8 PF10075.4 EIE86986.1 - 6.8e-29 100.4 0.6 1.4e-28 99.4 0.4 1.5 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 EIE86986.1 - 2.6e-27 95.7 0.5 3.7e-27 95.2 0.3 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Glutaredoxin PF00462.19 EIE86987.1 - 3.7e-34 116.5 0.0 2.9e-17 62.3 0.0 2.6 2 0 0 2 2 2 2 Glutaredoxin Thioredoxin PF00085.15 EIE86987.1 - 9.6e-10 38.0 0.1 3.4e-09 36.3 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin GST_N_3 PF13417.1 EIE86987.1 - 0.0036 17.4 0.0 0.28 11.4 0.0 2.5 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain ArsC PF03960.10 EIE86987.1 - 0.0044 17.0 0.0 5.3 7.1 0.0 2.8 3 0 0 3 3 3 2 ArsC family SH3BGR PF04908.10 EIE86987.1 - 0.017 15.0 0.0 3.7 7.5 0.0 2.5 2 0 0 2 2 2 0 SH3-binding, glutamic acid-rich protein HyaE PF07449.6 EIE86987.1 - 0.019 14.8 0.2 0.29 11.0 0.0 2.9 4 1 0 4 4 4 0 Hydrogenase-1 expression protein HyaE TrbC_Ftype PF09673.5 EIE86987.1 - 0.049 13.2 0.0 0.55 9.8 0.0 2.5 3 0 0 3 3 3 0 Type-F conjugative transfer system pilin assembly protein Phosducin PF02114.11 EIE86987.1 - 0.14 10.8 0.1 0.37 9.4 0.0 1.7 2 0 0 2 2 2 0 Phosducin SASP PF00269.15 EIE86987.1 - 0.15 11.9 0.4 11 5.9 0.0 2.7 2 0 0 2 2 2 0 Small, acid-soluble spore proteins, alpha/beta type Polysacc_deac_1 PF01522.16 EIE86988.1 - 2.8e-25 88.3 0.0 5.2e-25 87.4 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Cloacin_immun PF03513.9 EIE86988.1 - 0.1 12.6 0.1 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Cloacin immunity protein SAP18 PF06487.7 EIE86989.1 - 0.12 12.1 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Sin3 associated polypeptide p18 (SAP18) MIF4G PF02854.14 EIE86990.1 - 2.2e-43 148.1 0.9 2.2e-43 148.1 0.6 2.2 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.12 EIE86990.1 - 2.5e-16 59.3 4.3 3.3e-16 58.9 2.0 2.0 2 0 0 2 2 2 1 MA3 domain Actin PF00022.14 EIE86991.1 - 1.4e-32 112.6 0.0 1.7e-32 112.3 0.0 1.0 1 0 0 1 1 1 1 Actin AAA PF00004.24 EIE86992.1 - 1.1e-44 151.8 0.3 3.9e-44 150.0 0.0 2.0 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EIE86992.1 - 1.8e-09 37.4 0.1 5.3e-09 35.9 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EIE86992.1 - 5.4e-08 32.9 0.0 1.3e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EIE86992.1 - 4.1e-07 30.1 0.0 1.6e-06 28.2 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EIE86992.1 - 4.4e-06 26.8 0.8 0.00073 19.6 0.5 2.7 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 EIE86992.1 - 8e-06 24.9 0.0 1.6e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_19 PF13245.1 EIE86992.1 - 0.00014 21.5 0.1 0.00038 20.1 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 EIE86992.1 - 0.00016 21.5 0.0 0.00092 19.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EIE86992.1 - 0.0002 21.3 0.0 0.0004 20.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain UPF0079 PF02367.12 EIE86992.1 - 0.00028 20.4 0.1 0.015 14.8 0.0 2.5 1 1 1 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 RuvB_N PF05496.7 EIE86992.1 - 0.00048 19.2 0.0 0.0012 17.9 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 EIE86992.1 - 0.00054 19.4 0.7 0.012 15.0 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 EIE86992.1 - 0.00093 20.0 0.0 0.0054 17.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 EIE86992.1 - 0.0016 18.1 0.1 0.007 16.0 0.0 2.2 2 0 0 2 2 1 1 NTPase RNA_helicase PF00910.17 EIE86992.1 - 0.0017 18.5 0.0 0.0035 17.4 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_11 PF13086.1 EIE86992.1 - 0.003 17.1 1.0 0.0092 15.5 0.0 2.1 2 1 0 2 2 2 1 AAA domain NACHT PF05729.7 EIE86992.1 - 0.0031 17.1 0.1 0.053 13.1 0.0 2.4 2 0 0 2 2 2 1 NACHT domain IstB_IS21 PF01695.12 EIE86992.1 - 0.004 16.5 0.0 0.0097 15.3 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 EIE86992.1 - 0.0042 15.8 0.0 0.0077 14.9 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 EIE86992.1 - 0.0053 16.6 0.0 0.017 15.0 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_3 PF07726.6 EIE86992.1 - 0.006 16.1 0.0 0.017 14.7 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EIE86992.1 - 0.0067 16.7 0.1 0.053 13.8 0.0 2.4 2 1 1 3 3 2 1 AAA domain Mg_chelatase PF01078.16 EIE86992.1 - 0.0069 15.5 0.0 0.016 14.4 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.1 EIE86992.1 - 0.0076 15.8 0.0 0.017 14.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EIE86992.1 - 0.01 15.5 0.9 0.17 11.5 0.0 2.8 2 1 1 3 3 3 0 Archaeal ATPase AAA_24 PF13479.1 EIE86992.1 - 0.013 15.0 0.1 0.033 13.7 0.1 1.6 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EIE86992.1 - 0.016 14.3 1.4 0.45 9.5 0.0 2.8 3 0 0 3 3 3 0 KaiC Zeta_toxin PF06414.7 EIE86992.1 - 0.023 13.8 0.0 0.042 12.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Bac_DnaA PF00308.13 EIE86992.1 - 0.044 13.4 0.0 0.093 12.3 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein Sigma54_activat PF00158.21 EIE86992.1 - 0.045 13.2 0.1 1.2 8.5 0.0 2.7 3 0 0 3 3 2 0 Sigma-54 interaction domain ABC_tran PF00005.22 EIE86992.1 - 0.092 13.0 0.1 0.4 10.9 0.0 2.3 2 1 0 2 2 1 0 ABC transporter Parvo_NS1 PF01057.12 EIE86992.1 - 0.13 11.1 0.0 0.22 10.3 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.1 EIE86992.1 - 0.15 12.1 0.3 0.67 9.9 0.0 2.3 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_23 PF13476.1 EIE86992.1 - 0.17 12.2 6.2 1.3 9.2 0.0 2.4 2 1 0 2 2 2 0 AAA domain Ppx-GppA PF02541.11 EIE86993.1 - 6.5e-36 123.9 0.0 1.4e-35 122.8 0.0 1.5 1 1 0 1 1 1 1 Ppx/GppA phosphatase family HasA PF06438.7 EIE86994.1 - 0.089 12.1 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Heme-binding protein A (HasA) Glycos_transf_1 PF00534.15 EIE86995.1 - 3.5e-21 75.3 0.0 8.6e-21 74.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EIE86995.1 - 2.7e-07 30.7 0.0 7.9e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EIE86995.1 - 4e-07 30.2 0.0 1.2e-06 28.7 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferases group 1 MecA PF05389.7 EIE86996.1 - 0.011 15.3 1.4 0.013 15.0 0.9 1.2 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) DUF1397 PF07165.6 EIE86996.1 - 0.028 13.6 0.2 2.6 7.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1397) OmpH PF03938.9 EIE86996.1 - 0.03 14.2 1.3 0.044 13.7 1.0 1.3 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Erp_C PF06780.6 EIE86996.1 - 0.14 12.0 7.8 0.37 10.6 5.4 1.7 1 1 0 1 1 1 0 Erp protein C-terminus Mitofilin PF09731.4 EIE86996.1 - 0.17 10.5 6.3 0.2 10.2 3.8 1.3 1 1 0 1 1 1 0 Mitochondrial inner membrane protein Med9 PF07544.8 EIE86996.1 - 0.24 11.1 4.7 0.35 10.6 0.2 2.6 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Spt5_N PF11942.3 EIE86996.1 - 0.36 11.4 7.4 0.13 12.8 3.4 1.5 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal AAA_23 PF13476.1 EIE86996.1 - 0.57 10.4 9.7 1.4 9.1 6.7 1.6 1 1 0 1 1 1 0 AAA domain bZIP_2 PF07716.10 EIE86996.1 - 8.4 6.2 8.0 4.6 7.1 2.7 2.3 2 0 0 2 2 2 0 Basic region leucine zipper Syja_N PF02383.13 EIE86997.1 - 9e-71 238.2 3.9 4.2e-64 216.3 0.4 2.4 2 1 1 3 3 3 2 SacI homology domain 14-3-3 PF00244.15 EIE86998.1 - 3.2e-115 383.1 6.2 3.7e-115 382.9 4.3 1.0 1 0 0 1 1 1 1 14-3-3 protein Syntaxin_2 PF14523.1 EIE86998.1 - 0.0084 16.1 0.8 0.75 9.8 1.0 2.5 2 1 1 3 3 3 2 Syntaxin-like protein DUF327 PF03885.8 EIE86998.1 - 0.049 13.4 3.1 0.23 11.2 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF327) Imm7 PF15588.1 EIE86998.1 - 0.076 13.0 1.4 0.69 9.9 1.0 2.2 1 1 0 1 1 1 0 Immunity protein 7 TPR_12 PF13424.1 EIE86998.1 - 0.22 11.5 2.2 3.4 7.6 0.3 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat Ribosomal_S9 PF00380.14 EIE86999.1 - 2.8e-35 121.1 0.2 3.2e-35 121.0 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 LRR_6 PF13516.1 EIE87000.1 - 1.3e-06 27.8 3.9 0.076 13.1 0.0 4.8 5 0 0 5 5 5 3 Leucine Rich repeat LRR_4 PF12799.2 EIE87000.1 - 4e-06 26.3 1.9 0.012 15.1 0.1 2.8 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EIE87000.1 - 0.0012 18.5 3.2 18 5.8 0.0 5.1 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_9 PF14580.1 EIE87000.1 - 0.0069 15.9 0.3 0.01 15.4 0.2 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_7 PF13504.1 EIE87000.1 - 0.026 14.6 1.3 6.3 7.4 0.0 4.4 4 0 0 4 4 4 0 Leucine rich repeat LRR_8 PF13855.1 EIE87000.1 - 0.075 12.7 6.2 0.28 10.9 0.1 3.3 2 1 0 3 3 3 0 Leucine rich repeat Complex1_LYR_1 PF13232.1 EIE87002.1 - 2e-11 43.8 9.4 2.7e-11 43.5 2.6 2.3 2 0 0 2 2 2 1 Complex1_LYR-like Complex1_LYR PF05347.10 EIE87002.1 - 8e-11 41.5 4.0 8e-11 41.5 2.8 2.3 2 0 0 2 2 2 1 Complex 1 protein (LYR family) DUF4423 PF14394.1 EIE87002.1 - 0.017 14.6 0.3 0.028 13.9 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) DUF2262 PF10020.4 EIE87002.1 - 0.12 12.6 0.1 0.36 11.0 0.1 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2262) Pkinase PF00069.20 EIE87003.1 - 4.4e-63 212.8 0.0 8.2e-63 211.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE87003.1 - 1.5e-44 152.0 0.0 2.6e-44 151.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE87003.1 - 7.5e-07 28.3 0.0 2.9e-06 26.4 0.0 1.9 2 0 0 2 2 2 1 Kinase-like ABC1 PF03109.11 EIE87003.1 - 0.082 12.8 0.0 0.25 11.3 0.0 1.8 1 0 0 1 1 1 0 ABC1 family APH PF01636.18 EIE87003.1 - 0.12 12.1 0.4 0.2 11.3 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family bZIP_2 PF07716.10 EIE87003.1 - 1.7 8.5 11.7 1.7 8.4 0.1 2.9 2 1 0 2 2 2 0 Basic region leucine zipper 4HBT PF03061.17 EIE87004.1 - 0.011 15.7 0.5 7.1 6.8 0.0 2.9 3 0 0 3 3 3 0 Thioesterase superfamily Aldo_ket_red PF00248.16 EIE87005.1 - 1.6e-50 171.5 0.0 2e-50 171.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family GPI-anchored PF10342.4 EIE87007.1 - 1e-06 29.1 0.6 3.8e-06 27.2 0.4 2.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Leukemia_assc_2 PF15197.1 EIE87007.1 - 0.019 14.6 0.0 0.04 13.6 0.0 1.5 1 0 0 1 1 1 0 Leukemia-associated protein 2 XPG_I PF00867.13 EIE87007.1 - 0.074 13.1 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 XPG I-region Pkinase PF00069.20 EIE87008.1 - 3e-66 223.2 0.0 5.6e-66 222.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE87008.1 - 6.7e-41 140.0 0.0 1.1e-40 139.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE87008.1 - 8e-09 34.8 0.0 1.5e-07 30.7 0.0 2.2 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 EIE87008.1 - 0.00032 19.8 0.3 0.00076 18.5 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIE87008.1 - 0.0061 16.3 0.1 0.39 10.4 0.1 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family DUF3546 PF12066.3 EIE87008.1 - 0.45 10.5 4.8 1.2 9.1 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3546) CH PF00307.26 EIE87009.1 - 5.2e-15 55.4 0.0 6.8e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain Calponin PF00402.13 EIE87009.1 - 0.00057 19.1 5.3 0.0015 17.8 3.7 1.6 1 0 0 1 1 1 1 Calponin family repeat CAMSAP_CH PF11971.3 EIE87009.1 - 0.018 14.6 0.0 0.032 13.8 0.0 1.5 1 0 0 1 1 1 0 CAMSAP CH domain DUF4163 PF13739.1 EIE87009.1 - 0.25 12.1 4.6 0.5 11.1 1.7 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4163) Aldedh PF00171.17 EIE87010.1 - 2.2e-134 448.2 0.0 2.5e-134 448.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EIE87010.1 - 0.042 12.5 0.7 0.062 12.0 0.0 1.6 2 0 0 2 2 2 0 Acyl-CoA reductase (LuxC) DUF2407_C PF13373.1 EIE87012.1 - 1.2e-15 57.7 0.8 1.7e-15 57.1 0.5 1.2 1 0 0 1 1 1 1 DUF2407 C-terminal domain ubiquitin PF00240.18 EIE87012.1 - 2.7e-13 49.0 0.2 5.3e-13 48.1 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 EIE87012.1 - 2.7e-09 37.1 0.1 6e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD PF11976.3 EIE87012.1 - 8e-07 28.6 0.0 1.2e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 EIE87012.1 - 0.00081 19.2 0.0 0.0017 18.2 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like RPA PF10134.4 EIE87012.1 - 0.044 13.0 0.2 0.11 11.7 0.0 1.6 2 0 0 2 2 2 0 Replication initiator protein A Ribosomal_S19 PF00203.16 EIE87013.1 - 3.7e-24 84.1 0.0 4.7e-24 83.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 Chitin_synth_2 PF03142.10 EIE87014.1 - 7.1e-229 760.5 13.0 3.6e-115 385.3 0.5 2.1 1 1 1 2 2 2 2 Chitin synthase Glyco_tranf_2_3 PF13641.1 EIE87014.1 - 9.7e-11 41.8 0.0 0.00031 20.6 0.0 3.3 2 1 1 3 3 3 2 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 EIE87014.1 - 7.6e-08 32.0 0.0 1.7e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.1 EIE87014.1 - 1.4e-07 31.4 16.9 1.5e-05 24.8 4.7 3.3 3 1 1 4 4 4 2 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 EIE87014.1 - 0.0013 18.4 0.0 1.4 8.6 0.0 2.6 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EIE87014.1 - 0.036 13.3 0.0 4.3 6.5 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 21 DUF4014 PF13198.1 EIE87014.1 - 9 6.7 7.8 0.92 9.9 1.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4014) RRM_1 PF00076.17 EIE87016.1 - 4.1e-25 87.2 0.1 2.3e-11 43.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE87016.1 - 3e-15 55.7 0.0 7.5e-10 38.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE87016.1 - 4.5e-14 52.1 0.1 5.7e-06 26.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Aminotran_5 PF00266.14 EIE87017.1 - 1.5e-96 323.4 0.0 1.7e-96 323.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EIE87017.1 - 4.4e-10 39.1 0.0 6.4e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EIE87017.1 - 2.1e-06 27.0 0.0 3.7e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.14 EIE87017.1 - 0.0016 16.9 0.0 0.0026 16.2 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Tctex-1 PF03645.8 EIE87017.1 - 0.011 15.5 0.0 0.039 13.7 0.0 1.9 2 0 0 2 2 2 0 Tctex-1 family Ribosomal_S24e PF01282.14 EIE87017.1 - 0.021 14.6 0.1 0.045 13.5 0.1 1.6 1 0 0 1 1 1 0 Ribosomal protein S24e Cys_Met_Meta_PP PF01053.15 EIE87017.1 - 0.023 13.0 0.0 0.035 12.3 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Solute_trans_a PF03619.11 EIE87018.1 - 7.6e-13 48.3 0.9 1e-12 47.9 0.7 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Choline_transpo PF04515.7 EIE87019.1 - 3.1e-68 230.0 29.3 3.1e-68 230.0 20.3 2.8 1 1 1 2 2 2 1 Plasma-membrane choline transporter Nse5 PF08691.5 EIE87019.1 - 0.057 11.9 0.1 0.097 11.1 0.0 1.3 1 0 0 1 1 1 0 DNA repair proteins Nse5 and Nse6 DUF3353 PF11833.3 EIE87019.1 - 3.9 6.8 7.2 0.4 10.1 1.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3353) RhoGAP PF00620.22 EIE87021.1 - 4.5e-34 117.2 0.0 8.7e-34 116.3 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 EIE87021.1 - 2.6e-33 113.8 47.2 8.6e-14 51.3 4.6 5.2 5 0 0 5 5 5 4 LIM domain Atg14 PF10186.4 EIE87022.1 - 0.25 10.2 2.4 0.29 10.0 1.7 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Ribosomal_L32p PF01783.18 EIE87023.1 - 0.32 11.2 5.6 1.1 9.5 0.3 2.3 2 0 0 2 2 2 0 Ribosomal L32p protein family GDNF PF02351.11 EIE87023.1 - 0.46 11.0 4.5 0.45 11.0 2.5 1.4 1 1 0 1 1 1 0 GDNF/GAS1 domain ubiquitin PF00240.18 EIE87024.1 - 8.4e-103 335.8 16.9 5.3e-34 115.4 0.8 3.0 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.3 EIE87024.1 - 2.2e-58 193.8 14.2 5.4e-19 67.6 0.5 3.0 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EIE87024.1 - 8.7e-19 67.5 8.0 7.3e-05 22.9 0.1 4.5 3 3 0 3 3 3 3 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EIE87024.1 - 1.6e-15 57.2 0.3 0.0015 18.2 0.0 3.0 3 0 0 3 3 3 3 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EIE87024.1 - 6.3e-11 42.1 1.3 0.07 13.0 0.0 3.8 3 3 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EIE87024.1 - 1.4e-10 41.1 1.0 0.076 13.2 0.0 3.2 1 1 2 3 3 3 3 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 EIE87024.1 - 7.7e-08 32.2 0.0 0.99 9.4 0.0 3.6 3 0 0 3 3 3 3 Protein of unknown function (DUF2870) TUG-UBL1 PF11470.3 EIE87024.1 - 1.1e-05 25.2 2.7 2.2 8.2 0.0 3.2 3 0 0 3 3 3 3 GLUT4 regulating protein TUG Methyltrans_RNA PF04452.9 EIE87024.1 - 0.00088 18.4 0.2 1.2 8.2 0.0 2.3 2 0 0 2 2 2 2 RNA methyltransferase DUF3861 PF12977.2 EIE87024.1 - 0.00088 19.3 4.5 8.5 6.5 0.1 3.4 1 1 0 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3861) Big_3_3 PF13750.1 EIE87024.1 - 0.0012 18.2 0.0 15 4.9 0.0 3.2 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 3) FlgD_ig PF13860.1 EIE87024.1 - 0.0032 17.1 1.7 21 4.9 0.0 3.3 3 0 0 3 3 3 0 FlgD Ig-like domain ACT_4 PF13291.1 EIE87024.1 - 0.0037 17.5 0.6 37 4.7 0.0 3.3 3 0 0 3 3 3 0 ACT domain Plexin_cytopl PF08337.7 EIE87024.1 - 0.0048 15.2 8.2 2.5 6.2 0.2 4.5 4 2 0 4 4 4 2 Plexin cytoplasmic RasGAP domain USP7_C2 PF14533.1 EIE87024.1 - 0.0055 16.1 3.1 12 5.3 0.1 3.0 1 1 0 3 3 3 0 Ubiquitin-specific protease C-terminal GABP-alpha PF11620.3 EIE87024.1 - 0.0085 16.0 5.0 13 5.8 0.1 3.1 3 0 0 3 3 3 0 GA-binding protein alpha chain DUF3781 PF12636.2 EIE87024.1 - 0.015 15.2 4.6 21 5.1 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3781) CTDII PF01556.13 EIE87024.1 - 0.025 14.4 8.8 4 7.4 0.2 3.2 1 1 2 3 3 3 0 DnaJ C terminal domain DUF493 PF04359.9 EIE87024.1 - 0.05 13.9 0.2 96 3.4 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF493) EMG1 PF03587.9 EIE87024.1 - 0.059 12.6 0.9 16 4.6 0.0 2.9 3 0 0 3 3 3 0 EMG1/NEP1 methyltransferase Coagulin PF02035.10 EIE87024.1 - 0.081 12.6 1.9 50 3.4 0.0 3.1 3 0 0 3 3 3 0 Coagulin Tash_PEST PF07708.6 EIE87024.1 - 0.13 12.2 21.8 3.2 7.8 1.6 3.3 3 0 0 3 3 3 0 Tash protein PEST motif P2 PF07194.6 EIE87024.1 - 1.3 8.9 8.9 34 4.3 0.2 3.3 3 0 0 3 3 3 0 P2 response regulator binding domain FERM_N PF09379.5 EIE87024.1 - 3.1 7.9 7.5 1.1e+02 2.9 0.1 4.6 3 3 0 3 3 3 0 FERM N-terminal domain Myosin_N PF02736.14 EIE87024.1 - 3.8 7.2 5.5 77 3.0 0.1 3.4 3 0 0 3 3 3 0 Myosin N-terminal SH3-like domain Suf PF05843.9 EIE87025.1 - 6.2e-78 262.3 0.1 3.7e-77 259.7 0.0 2.2 3 0 0 3 3 3 1 Suppressor of forked protein (Suf) TPR_19 PF14559.1 EIE87025.1 - 2.7e-06 27.6 0.9 3.8e-05 23.9 0.5 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 EIE87025.1 - 1.9e-05 24.1 2.8 0.0043 16.8 0.0 3.2 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_15 PF13429.1 EIE87025.1 - 2.8e-05 23.3 3.7 0.0014 17.7 0.3 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EIE87025.1 - 9.5e-05 22.7 0.3 0.53 11.0 0.0 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EIE87025.1 - 0.00017 21.2 1.4 0.00062 19.3 1.0 2.1 1 0 0 1 1 1 1 TPR repeat TPR_3 PF07720.7 EIE87025.1 - 0.00098 18.8 0.7 0.22 11.3 0.2 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EIE87025.1 - 0.0025 17.7 3.1 0.15 12.0 0.2 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 EIE87025.1 - 0.007 17.0 5.6 0.14 12.9 0.4 3.7 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 EIE87025.1 - 0.016 15.6 0.3 6.5 7.4 0.0 3.5 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 EIE87025.1 - 0.036 14.2 0.7 0.46 10.8 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat IncA PF04156.9 EIE87025.1 - 0.05 13.2 4.4 0.1 12.1 3.0 1.4 1 0 0 1 1 1 0 IncA protein TPR_1 PF00515.23 EIE87025.1 - 0.062 12.9 2.2 0.27 10.9 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 EIE87025.1 - 0.22 11.6 5.8 0.099 12.7 1.7 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 EIE87025.1 - 0.36 10.7 7.0 7.6 6.5 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat OmpH PF03938.9 EIE87025.1 - 0.48 10.3 10.5 1 9.2 7.3 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) AbiH PF14253.1 EIE87025.1 - 5.1 6.6 8.6 6.9 6.1 4.9 1.7 1 1 0 1 1 1 0 Bacteriophage abortive infection AbiH Mitofilin PF09731.4 EIE87025.1 - 8.4 4.9 14.8 12 4.3 10.2 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein PT PF04886.7 EIE87026.1 - 3.9e-08 32.4 31.9 2.8e-07 29.7 11.1 3.5 3 0 0 3 3 3 2 PT repeat Imm42 PF15601.1 EIE87027.1 - 0.037 13.4 0.1 0.084 12.2 0.1 1.5 1 0 0 1 1 1 0 Immunity protein 42 BBE PF08031.7 EIE87027.1 - 0.088 12.7 1.7 0.71 9.8 0.1 2.4 2 0 0 2 2 2 0 Berberine and berberine like Homeobox_KN PF05920.6 EIE87028.1 - 6.6e-18 64.1 0.5 6.6e-18 64.1 0.3 1.9 2 0 0 2 2 2 1 Homeobox KN domain Homeobox PF00046.24 EIE87028.1 - 2.2e-08 33.5 0.7 4.5e-08 32.5 0.5 1.5 1 0 0 1 1 1 1 Homeobox domain DUF3446 PF11928.3 EIE87028.1 - 0.018 15.2 5.0 0.033 14.3 3.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) Peptidase_C7 PF01830.13 EIE87028.1 - 0.1 11.7 0.2 0.14 11.2 0.1 1.1 1 0 0 1 1 1 0 Peptidase C7 family SOBP PF15279.1 EIE87028.1 - 0.73 10.1 5.9 1.2 9.5 4.0 1.3 1 1 0 1 1 1 0 Sine oculis-binding protein CAF-1_p150 PF11600.3 EIE87028.1 - 0.97 8.7 3.5 1.7 8.0 2.4 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Kinesin PF00225.18 EIE87029.1 - 2.3e-79 266.5 2.7 2.3e-79 266.5 1.9 3.5 2 1 0 2 2 2 1 Kinesin motor domain DUF1890 PF09001.6 EIE87029.1 - 0.11 12.4 1.6 0.59 10.1 0.7 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1890) Tyr_Deacylase PF02580.11 EIE87032.1 - 1e-50 171.4 0.3 1.1e-50 171.3 0.2 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Rep_fac-A_C PF08646.5 EIE87032.1 - 0.029 14.0 0.1 0.037 13.7 0.1 1.2 1 0 0 1 1 1 0 Replication factor-A C terminal domain Sds3 PF08598.6 EIE87033.1 - 5.9e-18 65.1 22.7 5.9e-18 65.1 15.8 2.2 3 1 0 3 3 3 1 Sds3-like Tox-REase-5 PF15648.1 EIE87033.1 - 0.048 13.9 2.2 4.7 7.5 0.2 2.6 2 0 0 2 2 2 0 Restriction endonuclease fold toxin 5 RF-1 PF00472.15 EIE87035.1 - 8.2e-17 61.0 0.2 1.1e-16 60.5 0.1 1.1 1 0 0 1 1 1 1 RF-1 domain Lipoprotein_3 PF00938.12 EIE87035.1 - 0.42 10.4 3.7 0.25 11.1 0.1 2.1 2 0 0 2 2 2 0 Lipoprotein RRM_1 PF00076.17 EIE87036.1 - 5.2e-86 282.2 4.4 5.2e-22 77.2 0.5 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE87036.1 - 8.6e-55 182.6 0.7 2.4e-13 49.8 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE87036.1 - 2.6e-41 139.2 0.3 3.8e-09 36.2 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 EIE87036.1 - 2.1e-32 110.5 1.0 1.1e-31 108.3 0.8 2.2 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_3 PF08777.6 EIE87036.1 - 2e-05 24.3 7.6 0.016 15.0 2.0 4.0 3 1 1 4 4 4 2 RNA binding motif Nup35_RRM_2 PF14605.1 EIE87036.1 - 0.00022 20.8 0.4 7.4 6.4 0.0 4.2 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif OB_RNB PF08206.6 EIE87036.1 - 0.0023 17.4 3.9 1.2 8.7 0.0 3.5 3 0 0 3 3 3 1 Ribonuclease B OB domain PNPase PF03726.9 EIE87036.1 - 0.3 11.4 3.8 0.63 10.3 0.1 2.6 2 0 0 2 2 2 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain Hydrolase_6 PF13344.1 EIE87037.1 - 1.1e-28 99.1 0.0 2.9e-28 97.6 0.0 1.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EIE87037.1 - 2.1e-13 49.8 0.0 4.8e-13 48.6 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 EIE87037.1 - 2.8e-06 27.6 0.0 0.011 15.9 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EIE87037.1 - 4e-05 24.1 0.0 0.00037 20.9 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase LtrA PF06772.6 EIE87038.1 - 1.5e-19 70.1 25.9 1.7e-18 66.7 18.0 2.0 1 1 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) B12D PF06522.6 EIE87039.1 - 3.3e-16 58.7 0.0 3.9e-16 58.5 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit ECH PF00378.15 EIE87040.1 - 3.3e-62 209.8 0.0 3.7e-62 209.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family bZIP_1 PF00170.16 EIE87041.1 - 5.5e-11 42.2 7.2 1.2e-10 41.2 5.0 1.5 1 0 0 1 1 1 1 bZIP transcription factor DUF3425 PF11905.3 EIE87041.1 - 6e-10 39.1 6.4 6e-10 39.1 4.4 3.4 3 2 0 3 3 3 1 Domain of unknown function (DUF3425) HALZ PF02183.13 EIE87041.1 - 0.037 13.7 3.4 2.3 8.0 3.5 2.4 1 1 1 2 2 2 0 Homeobox associated leucine zipper DUF940 PF06082.6 EIE87041.1 - 0.73 8.3 5.0 0.93 7.9 3.5 1.1 1 0 0 1 1 1 0 Bacterial putative lipoprotein (DUF940) bZIP_Maf PF03131.12 EIE87041.1 - 2.7 8.3 21.1 0.56 10.5 4.7 2.3 2 0 0 2 2 2 0 bZIP Maf transcription factor DUF904 PF06005.7 EIE87041.1 - 4.3 7.7 10.2 0.091 13.0 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF904) DUF4140 PF13600.1 EIE87041.1 - 5.9 7.4 9.1 1.3 9.5 1.5 2.5 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Glyco_transf_5 PF08323.6 EIE87042.1 - 1.1e-13 51.3 0.2 1.9e-12 47.1 0.1 2.8 2 1 0 2 2 2 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.15 EIE87042.1 - 1.6e-07 30.8 0.0 3.6e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EIE87042.1 - 0.00079 19.5 0.0 0.0021 18.2 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferases group 1 Corona_S2 PF01601.11 EIE87042.1 - 0.21 9.6 0.3 0.31 9.0 0.2 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein zf-C3HC4_3 PF13920.1 EIE87043.1 - 2.4e-06 27.1 8.4 2.4e-06 27.1 5.9 2.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIE87043.1 - 0.00015 21.4 9.2 0.00015 21.4 6.4 1.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 EIE87043.1 - 0.0015 18.1 8.3 0.0015 18.1 5.8 2.5 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIE87043.1 - 0.0056 16.3 9.6 0.0056 16.3 6.7 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EIE87043.1 - 0.0072 16.3 10.6 0.0072 16.3 7.4 2.1 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 EIE87043.1 - 0.54 10.2 9.4 2.1 8.3 6.5 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain DZR PF12773.2 EIE87043.1 - 4.1 7.3 9.4 4.3 7.2 3.3 2.6 2 1 0 2 2 2 0 Double zinc ribbon Zn_Tnp_IS91 PF14319.1 EIE87043.1 - 7.1 6.1 12.7 0.21 11.1 2.6 2.5 1 1 1 2 2 2 0 Transposase zinc-binding domain RNase_HII PF01351.13 EIE87044.1 - 0.31 10.6 2.0 0.17 11.5 0.1 1.5 2 0 0 2 2 2 0 Ribonuclease HII Thaumatin PF00314.12 EIE87045.1 - 1.3e-42 145.6 15.9 1.3e-41 142.4 11.1 1.9 1 1 0 1 1 1 1 Thaumatin family DDE_3 PF13358.1 EIE87046.1 - 2.7e-05 23.9 0.0 3.6e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease TPR_11 PF13414.1 EIE87047.1 - 8.5e-18 63.7 7.7 1.8e-09 37.1 0.3 5.4 4 2 2 6 6 6 4 TPR repeat TPR_2 PF07719.12 EIE87047.1 - 1.4e-17 62.0 5.5 3.6e-06 26.4 0.3 7.3 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.23 EIE87047.1 - 2e-12 46.1 13.3 2.7e-07 29.8 0.3 5.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.1 EIE87047.1 - 4.5e-12 45.7 5.6 0.00012 21.9 0.0 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 EIE87047.1 - 6.9e-12 45.5 0.7 0.052 13.8 0.0 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 EIE87047.1 - 8.7e-12 45.3 0.7 0.0002 21.9 0.0 4.8 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 EIE87047.1 - 6.9e-09 35.2 0.9 0.88 9.9 0.0 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 EIE87047.1 - 2.6e-08 33.7 2.8 0.86 10.4 0.0 6.3 4 2 4 8 8 7 2 Tetratricopeptide repeat TPR_8 PF13181.1 EIE87047.1 - 3.9e-07 29.3 7.2 0.00019 20.9 0.2 5.5 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 EIE87047.1 - 4.4e-07 29.2 0.5 0.046 13.5 0.0 4.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 EIE87047.1 - 7.4e-05 22.9 10.6 0.011 16.0 0.0 5.6 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_9 PF13371.1 EIE87047.1 - 0.00014 21.6 1.3 1.2 9.0 0.0 4.5 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.1 EIE87047.1 - 0.0015 17.6 11.1 0.021 13.9 0.6 4.4 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.1 EIE87047.1 - 0.0055 16.6 9.4 0.14 12.1 0.2 4.4 5 0 0 5 5 5 2 Tetratricopeptide repeat MIT PF04212.13 EIE87047.1 - 0.061 13.2 0.4 0.061 13.2 0.3 2.8 4 0 0 4 4 3 0 MIT (microtubule interacting and transport) domain DUF2981 PF11200.3 EIE87048.1 - 0.83 8.6 4.0 0.92 8.5 2.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) AAA PF00004.24 EIE87049.1 - 2.3e-61 205.7 0.0 5.3e-42 143.1 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EIE87049.1 - 2.5e-10 41.2 0.0 0.0008 20.2 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EIE87049.1 - 4.5e-10 39.8 0.8 0.0039 17.1 0.0 3.6 2 1 0 3 3 3 2 AAA ATPase domain AAA_18 PF13238.1 EIE87049.1 - 2.5e-07 31.0 0.0 0.032 14.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EIE87049.1 - 3.6e-07 30.3 1.0 0.0058 16.7 0.1 4.0 2 2 2 4 4 4 2 AAA domain AAA_5 PF07728.9 EIE87049.1 - 4e-07 29.8 0.0 0.0079 15.9 0.0 3.3 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EIE87049.1 - 6.4e-07 29.3 0.0 0.014 15.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 EIE87049.1 - 7.7e-07 29.2 0.0 0.028 14.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 EIE87049.1 - 1.1e-06 28.7 0.0 0.033 14.3 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_25 PF13481.1 EIE87049.1 - 3.6e-06 26.5 0.5 0.0017 17.7 0.2 3.3 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EIE87049.1 - 1.2e-05 24.5 0.0 0.0017 17.4 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EIE87049.1 - 1.2e-05 25.1 0.0 0.055 13.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 EIE87049.1 - 3.4e-05 23.3 0.0 0.00074 18.9 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein TIP49 PF06068.8 EIE87049.1 - 7.1e-05 21.6 0.0 0.0085 14.8 0.0 2.3 2 0 0 2 2 2 1 TIP49 C-terminus AAA_19 PF13245.1 EIE87049.1 - 0.0001 21.9 0.8 0.0017 18.0 0.0 3.1 3 0 0 3 3 3 1 Part of AAA domain NACHT PF05729.7 EIE87049.1 - 0.00019 21.1 0.0 0.72 9.4 0.0 3.2 3 0 0 3 3 3 2 NACHT domain DUF815 PF05673.8 EIE87049.1 - 0.0002 20.3 0.0 0.21 10.4 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_2 PF07724.9 EIE87049.1 - 0.00026 20.9 0.0 0.014 15.2 0.0 2.6 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.16 EIE87049.1 - 0.00034 19.8 0.1 0.02 14.0 0.1 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI UPF0079 PF02367.12 EIE87049.1 - 0.00053 19.5 0.0 0.21 11.2 0.0 2.6 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 EIE87049.1 - 0.00062 19.5 0.1 0.75 9.4 0.0 2.7 2 1 1 3 3 3 1 Archaeal ATPase ABC_tran PF00005.22 EIE87049.1 - 0.00095 19.4 0.0 1.7 8.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter Parvo_NS1 PF01057.12 EIE87049.1 - 0.0012 17.7 0.0 0.0022 16.9 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 NTPase_1 PF03266.10 EIE87049.1 - 0.002 17.8 0.0 2.2 7.9 0.0 2.5 2 0 0 2 2 2 2 NTPase AAA_24 PF13479.1 EIE87049.1 - 0.0023 17.5 0.3 0.065 12.8 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EIE87049.1 - 0.0025 17.3 0.5 0.33 10.4 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain KaiC PF06745.8 EIE87049.1 - 0.0047 16.0 0.0 0.011 14.9 0.0 1.5 1 0 0 1 1 1 1 KaiC AAA_30 PF13604.1 EIE87049.1 - 0.01 15.4 0.2 2 7.9 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_10 PF12846.2 EIE87049.1 - 0.011 15.1 0.3 3.1 7.1 0.0 2.8 3 0 0 3 3 2 0 AAA-like domain Vps4_C PF09336.5 EIE87049.1 - 0.012 15.4 0.0 0.82 9.6 0.0 2.8 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain AAA_23 PF13476.1 EIE87049.1 - 0.016 15.5 0.0 4.3 7.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.10 EIE87049.1 - 0.016 13.9 0.0 0.11 11.1 0.0 2.1 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_3 PF07726.6 EIE87049.1 - 0.025 14.1 0.0 0.27 10.8 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 EIE87049.1 - 0.025 13.4 0.0 1.3 7.8 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain SKI PF01202.17 EIE87049.1 - 0.028 14.2 0.4 4.9 7.0 0.0 2.8 3 0 0 3 3 2 0 Shikimate kinase Sigma54_activat PF00158.21 EIE87049.1 - 0.036 13.5 0.0 0.57 9.6 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain Zeta_toxin PF06414.7 EIE87049.1 - 0.037 13.1 0.0 0.25 10.4 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin PhoH PF02562.11 EIE87049.1 - 0.045 12.9 0.1 0.11 11.7 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_11 PF13086.1 EIE87049.1 - 0.082 12.4 0.0 1.3 8.5 0.0 2.6 3 0 0 3 3 3 0 AAA domain T2SE PF00437.15 EIE87049.1 - 0.091 11.6 0.0 3.1 6.6 0.0 2.6 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF258 PF03193.11 EIE87049.1 - 0.14 11.3 0.0 3.1 6.9 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function, DUF258 Transposase_31 PF04754.7 EIE87050.1 - 0.023 14.0 0.0 0.05 12.9 0.0 1.5 1 0 0 1 1 1 0 Putative transposase, YhgA-like AKAP95 PF04988.7 EIE87050.1 - 0.12 12.1 1.1 0.17 11.6 0.1 1.8 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) PRESAN PF09687.5 EIE87050.1 - 0.25 11.3 3.1 9.5 6.3 0.2 2.2 2 0 0 2 2 2 0 Plasmodium RESA N-terminal Ribosomal_S20p PF01649.13 EIE87050.1 - 1.2 9.5 4.8 0.22 11.9 0.4 1.9 2 0 0 2 2 2 0 Ribosomal protein S20 RabGAP-TBC PF00566.13 EIE87052.1 - 3.2e-38 131.3 11.0 3.2e-36 124.8 1.9 3.9 2 1 0 2 2 2 1 Rab-GTPase-TBC domain CRISPR_Cse2 PF09485.5 EIE87052.1 - 0.092 12.7 1.7 1.2 9.1 0.1 2.5 2 0 0 2 2 2 0 CRISPR-associated protein Cse2 (CRISPR_cse2) Shugoshin_N PF07558.6 EIE87052.1 - 0.5 10.1 11.6 0.068 12.8 0.6 3.5 3 1 0 3 3 3 0 Shugoshin N-terminal coiled-coil region DivIC PF04977.10 EIE87052.1 - 0.81 9.2 23.3 1.9 8.0 0.7 4.7 2 1 1 4 4 4 0 Septum formation initiator ERM PF00769.14 EIE87052.1 - 7.5 6.0 31.7 0.065 12.7 7.5 2.9 1 1 2 3 3 3 0 Ezrin/radixin/moesin family HSP70 PF00012.15 EIE87053.1 - 1.4e-123 412.9 0.7 1.5e-123 412.8 0.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EIE87053.1 - 3.9e-13 48.7 0.1 7.5e-11 41.1 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Hydantoinase_A PF01968.13 EIE87053.1 - 0.00048 19.3 3.0 0.0084 15.2 0.2 2.2 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase FtsA PF14450.1 EIE87053.1 - 0.006 16.4 2.7 0.24 11.2 0.3 3.1 2 1 0 2 2 2 1 Cell division protein FtsA DDR PF08841.5 EIE87053.1 - 0.02 13.7 0.3 0.029 13.2 0.2 1.3 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DDE_3 PF13358.1 EIE87054.1 - 2.7e-05 23.9 0.0 3.6e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-RVT PF13966.1 EIE87055.1 - 2.3e-05 24.6 1.4 5.2e-05 23.4 0.7 1.8 1 1 0 1 1 1 1 zinc-binding in reverse transcriptase Exo_endo_phos PF03372.18 EIE87056.1 - 4e-14 53.1 1.9 8.7e-14 52.0 1.3 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EIE87056.1 - 1e-05 25.0 0.3 2.5e-05 23.8 0.1 1.8 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase DUF1759 PF03564.10 EIE87059.1 - 6e-06 26.1 0.6 7e-06 25.9 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) Transposase_21 PF02992.9 EIE87060.1 - 5.4e-23 81.2 0.1 5.4e-23 81.2 0.1 1.6 2 0 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.1 EIE87060.1 - 5.4e-05 22.6 0.3 0.00012 21.5 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Lzipper-MIP1 PF14389.1 EIE87061.1 - 0.0049 16.9 0.4 0.013 15.5 0.3 1.7 1 0 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 ChaB PF06150.7 EIE87061.1 - 0.069 12.9 0.6 0.25 11.1 0.1 2.2 2 0 0 2 2 2 0 ChaB IncA PF04156.9 EIE87061.1 - 0.17 11.5 1.2 0.28 10.7 0.9 1.4 1 0 0 1 1 1 0 IncA protein DUF4404 PF14357.1 EIE87061.1 - 0.21 11.9 1.9 5.7 7.4 0.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) SRR PF07709.6 EIE87061.1 - 0.23 11.7 4.4 5.5 7.6 0.0 3.6 3 0 0 3 3 3 0 Seven Residue Repeat DDE_3 PF13358.1 EIE87062.1 - 6e-22 77.9 0.3 1.1e-21 77.0 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE87062.1 - 1.3e-15 57.2 1.6 6.4e-15 54.9 0.2 2.7 3 0 0 3 3 3 1 Transposase HTH_29 PF13551.1 EIE87062.1 - 1.2e-05 25.4 0.2 4.9e-05 23.4 0.1 2.0 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.1 EIE87062.1 - 0.00018 22.2 3.6 0.01 16.6 0.1 3.8 3 1 1 4 4 4 1 Homeodomain-like domain HTH_38 PF13936.1 EIE87062.1 - 0.00071 19.0 0.0 0.0016 17.9 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_21 PF13276.1 EIE87062.1 - 0.0012 18.7 0.1 0.1 12.6 0.0 2.8 3 0 0 3 3 3 1 HTH-like domain rve PF00665.21 EIE87062.1 - 0.0019 18.2 0.0 0.0052 16.8 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain HTH_23 PF13384.1 EIE87062.1 - 0.0033 17.0 0.0 0.062 12.9 0.0 2.6 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.1 EIE87062.1 - 0.011 15.7 0.0 0.058 13.4 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_7 PF02796.10 EIE87062.1 - 0.026 14.3 1.5 0.85 9.5 0.1 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain of resolvase Chromo PF00385.19 EIE87063.1 - 6.4e-10 38.5 0.2 1.3e-09 37.5 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain YcgR_2 PF12945.2 EIE87063.1 - 0.04 13.7 0.0 0.077 12.8 0.0 1.5 1 0 0 1 1 1 0 Flagellar protein YcgR S1_2 PF13509.1 EIE87063.1 - 0.11 12.3 0.0 0.31 10.9 0.0 1.7 1 0 0 1 1 1 0 S1 domain RVT_1 PF00078.22 EIE87064.1 - 6.7e-12 45.2 0.3 1.2e-11 44.4 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EIE87065.1 - 1.5e-16 60.5 0.0 3.3e-16 59.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 EIE87065.1 - 2.9e-09 36.4 0.3 6.5e-09 35.3 0.2 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 EIE87065.1 - 0.0093 15.6 0.2 0.035 13.8 0.1 1.9 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain HTH_Tnp_Tc3_2 PF01498.13 EIE87066.1 - 4.7e-06 26.5 1.1 4.7e-06 26.5 0.8 1.9 1 1 1 2 2 2 1 Transposase Sigma70_r1_2 PF00140.15 EIE87066.1 - 0.0021 17.6 0.1 0.0038 16.8 0.1 1.4 1 0 0 1 1 1 1 Sigma-70 factor, region 1.2 rve PF00665.21 EIE87067.1 - 1.3e-17 64.0 0.0 3.7e-17 62.5 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE87067.1 - 4.1e-14 52.4 0.9 1e-13 51.1 0.6 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE87067.1 - 1.3e-06 27.9 1.3 5.6e-06 25.9 0.7 2.2 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.1 EIE87067.1 - 9.2e-05 22.8 0.1 0.00087 19.7 0.0 2.4 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.15 EIE87067.1 - 0.00062 19.6 0.1 0.0022 17.8 0.0 2.0 1 0 0 1 1 1 1 Retroviral aspartyl protease Tudor-knot PF11717.3 EIE87067.1 - 0.019 14.6 0.7 0.054 13.2 0.5 1.8 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain YcgR_2 PF12945.2 EIE87067.1 - 0.032 14.0 0.0 0.42 10.5 0.0 2.5 2 0 0 2 2 2 0 Flagellar protein YcgR gag-asp_proteas PF13975.1 EIE87067.1 - 0.07 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease YrhC PF14143.1 EIE87069.1 - 0.085 12.8 0.4 0.14 12.0 0.1 1.5 2 0 0 2 2 2 0 YrhC-like protein DUF4534 PF15049.1 EIE87069.1 - 0.1 12.1 4.5 0.12 12.0 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4534) HTH_Tnp_Tc3_2 PF01498.13 EIE87070.1 - 2.1e-12 46.9 0.9 2.1e-12 46.9 0.6 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.1 EIE87070.1 - 5.1e-12 45.7 0.0 1e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 EIE87070.1 - 9e-05 22.5 0.2 0.00022 21.3 0.1 1.7 2 0 0 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.1 EIE87070.1 - 0.00063 19.3 0.1 0.0016 18.0 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_7 PF02796.10 EIE87070.1 - 0.0049 16.7 0.0 0.013 15.3 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_30 PF13556.1 EIE87070.1 - 0.017 14.7 0.0 0.11 12.0 0.0 2.0 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain HTH_38 PF13936.1 EIE87070.1 - 0.021 14.3 0.0 0.071 12.6 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_32 PF13565.1 EIE87070.1 - 0.023 15.5 1.6 0.81 10.5 0.2 2.7 2 1 0 2 2 2 0 Homeodomain-like domain RecX PF02631.11 EIE87070.1 - 0.079 13.1 0.3 0.15 12.2 0.2 1.5 1 0 0 1 1 1 0 RecX family DDE_3 PF13358.1 EIE87071.1 - 7.7e-10 38.6 0.1 4.5e-05 23.2 0.5 2.3 1 1 1 2 2 2 2 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE87071.1 - 0.0026 17.7 0.2 0.0041 17.1 0.1 1.3 1 0 0 1 1 1 1 Transposase DUF342 PF03961.8 EIE87072.1 - 0.011 14.1 2.5 0.016 13.6 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) IncA PF04156.9 EIE87072.1 - 0.022 14.3 0.3 0.028 13.9 0.2 1.3 1 0 0 1 1 1 0 IncA protein FlxA PF14282.1 EIE87072.1 - 0.027 14.3 3.7 0.21 11.5 2.6 2.2 1 1 0 1 1 1 0 FlxA-like protein BLOC1_2 PF10046.4 EIE87072.1 - 0.049 13.7 4.8 2.3 8.3 0.1 2.5 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Golgin_A5 PF09787.4 EIE87072.1 - 0.66 8.4 9.4 0.38 9.2 4.6 1.6 1 1 1 2 2 2 0 Golgin subfamily A member 5 V_ATPase_I PF01496.14 EIE87072.1 - 1.9 6.2 7.2 2 6.1 4.3 1.4 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family V-SNARE PF05008.10 EIE87072.1 - 2 8.6 10.2 0.42 10.8 4.3 1.9 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus RVT_1 PF00078.22 EIE87074.1 - 1.9e-16 60.0 0.1 3.2e-16 59.3 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-C2H2 PF00096.21 EIE87075.1 - 1.2e-07 31.6 18.1 0.00054 20.1 4.1 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIE87075.1 - 5.6e-06 26.3 19.2 0.00023 21.3 4.7 3.9 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EIE87075.1 - 0.00078 19.6 14.6 0.15 12.4 1.7 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger Hid1 PF12722.2 EIE87076.1 - 2.9e-91 306.5 13.3 1.5e-57 194.9 2.7 3.9 1 1 2 3 3 3 3 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 EIE87076.1 - 2e-39 135.3 0.0 2.1e-32 112.1 0.0 2.0 1 1 1 2 2 2 2 Dyggve-Melchior-Clausen syndrome protein Spo7 PF03907.8 EIE87077.1 - 0.027 14.0 1.2 0.039 13.5 0.8 1.2 1 0 0 1 1 1 0 Spo7-like protein TMEM138 PF14935.1 EIE87077.1 - 0.54 10.5 6.7 0.35 11.2 3.2 1.7 2 0 0 2 2 2 0 Transmembrane protein 138 p450 PF00067.17 EIE87079.1 - 4.7e-74 249.5 0.0 5.7e-74 249.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 LSM PF01423.17 EIE87080.1 - 1.8e-20 72.2 0.0 2.1e-20 72.0 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EIE87080.1 - 0.0033 17.3 0.0 0.0039 17.0 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF669 PF05037.8 EIE87080.1 - 0.043 13.7 0.0 0.057 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF669) UPF0113 PF03657.8 EIE87080.1 - 0.096 12.3 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0113) Peptidase_M19 PF01244.16 EIE87083.1 - 4.8e-101 337.8 0.0 9.3e-101 336.9 0.0 1.5 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) AMP-binding PF00501.23 EIE87083.1 - 4.5e-90 302.0 0.0 1.6e-89 300.2 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme UN_NPL4 PF11543.3 EIE87083.1 - 0.33 11.2 1.5 1.9 8.8 0.0 2.9 3 0 0 3 3 3 0 Nuclear pore localisation protein NPL4 Cation_efflux PF01545.16 EIE87084.1 - 5.2e-35 120.9 6.2 5.9e-35 120.7 4.3 1.0 1 0 0 1 1 1 1 Cation efflux family TPT PF03151.11 EIE87084.1 - 0.00041 20.0 0.2 0.065 12.8 0.0 2.1 1 1 1 2 2 2 2 Triose-phosphate Transporter family TMEM141 PF15110.1 EIE87084.1 - 0.015 15.5 0.5 0.31 11.3 0.1 2.1 1 1 1 2 2 2 0 TMEM141 protein family DUF3360 PF11840.3 EIE87084.1 - 0.043 12.1 0.0 0.058 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3360) YfhO PF09586.5 EIE87084.1 - 0.045 11.7 0.0 0.052 11.5 0.0 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF441 PF04284.8 EIE87084.1 - 0.14 12.0 2.8 0.19 11.5 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF441) GtrA PF04138.9 EIE87084.1 - 0.15 12.0 6.4 0.73 9.8 4.5 1.9 1 1 0 1 1 1 0 GtrA-like protein Glyco_transf_22 PF03901.12 EIE87084.1 - 0.3 10.0 2.9 1.1 8.2 1.0 1.9 1 1 1 2 2 2 0 Alg9-like mannosyltransferase family EphA2_TM PF14575.1 EIE87084.1 - 0.5 10.7 2.5 2.2 8.7 0.0 2.5 2 1 1 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain PAP2 PF01569.16 EIE87084.1 - 1 9.0 5.0 5.5 6.6 3.5 2.1 1 1 0 1 1 1 0 PAP2 superfamily Polysacc_synt_C PF14667.1 EIE87084.1 - 1.6 8.5 7.8 3.1 7.5 0.5 2.1 1 1 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain PMT PF02366.13 EIE87085.1 - 2.1e-31 109.1 29.3 4.5e-18 65.4 5.0 3.1 2 1 1 3 3 3 2 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EIE87085.1 - 1.8e-29 102.6 1.4 3.7e-29 101.6 0.9 1.5 1 1 0 1 1 1 1 MIR domain PMT_2 PF13231.1 EIE87085.1 - 1.5 8.7 20.9 0.76 9.6 7.9 2.5 2 1 0 2 2 2 0 Dolichyl-phosphate-mannose-protein mannosyltransferase MBOAT_2 PF13813.1 EIE87086.1 - 1.2e-10 41.2 5.8 2.3e-10 40.3 0.1 2.9 2 1 1 3 3 3 1 Membrane bound O-acyl transferase family DUF3810 PF12725.2 EIE87086.1 - 1 8.1 6.6 2 7.2 4.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) Ribosomal_L27e PF01777.13 EIE87087.1 - 5.5e-37 125.7 7.1 5.5e-37 125.7 4.9 1.7 2 0 0 2 2 2 1 Ribosomal L27e protein family KOW PF00467.24 EIE87087.1 - 5.7e-06 25.8 1.1 1.7e-05 24.3 0.8 1.8 1 0 0 1 1 1 1 KOW motif Ribosomal_S2 PF00318.15 EIE87088.1 - 4.8e-43 146.8 0.2 6.2e-21 74.6 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 Ribosomal_S8e PF01201.17 EIE87091.1 - 1.5e-40 138.3 6.5 6.4e-39 133.1 4.5 2.2 1 1 0 1 1 1 1 Ribosomal protein S8e DUF573 PF04504.9 EIE87091.1 - 5.6 7.3 8.4 14 6.0 5.2 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF573 Ribosomal_L13e PF01294.13 EIE87092.1 - 9.4e-78 259.7 6.8 1.4e-77 259.2 4.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e DUF3959 PF13105.1 EIE87092.1 - 0.079 12.2 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) Lipase_3 PF01764.20 EIE87093.1 - 2e-14 53.4 0.0 3.3e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EIE87093.1 - 0.16 11.6 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family F_bP_aldolase PF01116.15 EIE87094.1 - 1.1e-99 333.2 0.0 1.2e-99 333.0 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II PX PF00787.19 EIE87094.1 - 0.0047 16.6 0.0 8.8 6.1 0.0 3.1 3 0 0 3 3 3 2 PX domain Peptidase_C26 PF07722.8 EIE87094.1 - 0.055 12.8 0.1 0.58 9.5 0.0 2.1 2 0 0 2 2 2 0 Peptidase C26 UQ_con PF00179.21 EIE87095.1 - 2.2e-44 150.2 0.0 3.1e-44 149.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EIE87095.1 - 6.5e-06 25.9 0.0 8.2e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EIE87095.1 - 0.00058 19.7 0.0 0.00079 19.3 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 EIE87095.1 - 0.009 15.6 0.0 0.017 14.7 0.0 1.5 1 0 0 1 1 1 1 UEV domain Bromodomain PF00439.20 EIE87096.1 - 8.4e-93 304.4 7.3 2e-25 88.4 0.0 5.1 4 0 0 4 4 4 4 Bromodomain Peptidase_M1 PF01433.15 EIE87096.1 - 9.8e-08 31.4 0.2 4.5e-05 22.7 0.0 3.0 3 0 0 3 3 3 2 Peptidase family M1 HEAT_2 PF13646.1 EIE87096.1 - 0.0027 17.9 0.0 0.037 14.3 0.0 2.7 3 0 0 3 3 3 1 HEAT repeats Peptidase_MA_2 PF13485.1 EIE87096.1 - 0.0064 16.5 0.0 0.021 14.8 0.0 1.8 1 0 0 1 1 1 1 Peptidase MA superfamily RNB PF00773.14 EIE87097.1 - 5.2e-95 318.4 0.0 9.1e-95 317.6 0.0 1.4 1 0 0 1 1 1 1 RNB domain WD40 PF00400.27 EIE87099.1 - 6.6e-17 60.6 3.5 3.2e-05 23.6 0.0 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat eIF2A PF08662.6 EIE87099.1 - 0.047 13.3 0.0 0.67 9.6 0.0 2.6 1 1 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 EIE87099.1 - 0.062 12.0 0.2 0.35 9.5 0.0 2.0 2 1 0 3 3 3 0 Nup133 N terminal like Radical_SAM PF04055.16 EIE87100.1 - 0.099 12.8 0.1 0.22 11.7 0.0 1.6 2 1 0 2 2 2 0 Radical SAM superfamily Stathmin PF00836.14 EIE87101.1 - 3.1 7.4 6.3 19 4.9 0.0 3.7 4 1 0 4 4 4 0 Stathmin family Mito_carr PF00153.22 EIE87102.1 - 3e-15 55.6 3.2 4.2e-08 32.7 0.1 3.3 3 0 0 3 3 3 2 Mitochondrial carrier protein GHMP_kinases_N PF00288.21 EIE87102.1 - 1.1e-06 28.6 0.0 3.8e-06 26.8 0.0 2.1 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EIE87102.1 - 0.00081 19.5 0.0 0.0022 18.1 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal NTP_transf_3 PF12804.2 EIE87102.1 - 0.029 14.4 0.0 0.083 12.9 0.0 1.7 1 0 0 1 1 1 0 MobA-like NTP transferase domain Phosphodiest PF01663.17 EIE87103.1 - 1.5e-81 274.5 0.1 1.7e-81 274.3 0.1 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EIE87103.1 - 2.5e-05 23.6 0.1 0.0049 16.1 0.1 2.5 1 1 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 EIE87103.1 - 0.0051 16.2 0.0 0.0074 15.6 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily PglZ PF08665.7 EIE87103.1 - 0.03 13.9 0.0 0.045 13.4 0.0 1.2 1 0 0 1 1 1 0 PglZ domain Aldo_ket_red PF00248.16 EIE87104.1 - 1.3e-52 178.3 0.0 1.6e-52 178.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Glyco_transf_8 PF01501.15 EIE87106.1 - 2.6e-16 59.7 0.7 5.4e-16 58.6 0.5 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 8 Glyco_transf_64 PF09258.5 EIE87106.1 - 2e-06 27.1 0.0 3.1e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Rad60-SLD PF11976.3 EIE87106.1 - 0.01 15.5 0.0 0.24 11.0 0.0 2.8 3 1 0 3 3 3 1 Ubiquitin-2 like Rad60 SUMO-like Nucleotid_trans PF03407.11 EIE87106.1 - 0.013 15.3 0.1 0.025 14.3 0.1 1.4 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase Med17 PF10156.4 EIE87107.1 - 1.3e-37 129.2 13.3 1.8e-37 128.7 9.2 1.2 1 0 0 1 1 1 1 Subunit 17 of Mediator complex Mre11_DNA_bind PF04152.9 EIE87109.1 - 5.6e-44 150.0 0.1 1.2e-43 149.0 0.0 1.5 1 0 0 1 1 1 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 EIE87109.1 - 2.5e-25 89.0 0.8 3.9e-25 88.4 0.5 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EIE87109.1 - 6.1e-08 32.6 0.0 2.4e-07 30.7 0.0 2.0 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Tagatose_6_P_K PF08013.6 EIE87109.1 - 0.028 12.8 0.1 2.7 6.3 0.0 2.9 3 0 0 3 3 3 0 Tagatose 6 phosphate kinase PPR_2 PF13041.1 EIE87110.1 - 2.5e-42 142.6 19.8 1.1e-09 38.1 0.1 9.7 8 3 2 10 10 10 7 PPR repeat family Brix PF04427.13 EIE87110.1 - 2e-33 115.6 0.4 2e-33 115.6 0.3 1.9 2 0 0 2 2 2 1 Brix domain PPR_3 PF13812.1 EIE87110.1 - 8.6e-28 94.2 6.5 0.00014 21.8 0.0 9.7 10 0 0 10 10 10 6 Pentatricopeptide repeat domain PPR PF01535.15 EIE87110.1 - 6.3e-22 75.9 16.9 4.7e-05 23.0 0.1 10.2 11 0 0 11 11 11 4 PPR repeat PPR_1 PF12854.2 EIE87110.1 - 2.9e-11 42.6 6.4 1.6e-06 27.4 0.0 7.0 9 0 0 9 9 9 2 PPR repeat ECSIT PF06239.6 EIE87110.1 - 0.00074 18.4 2.5 0.64 8.8 0.1 4.0 3 1 1 4 4 4 2 Evolutionarily conserved signalling intermediate in Toll pathway BTAD PF03704.12 EIE87110.1 - 0.001 19.3 5.1 3.8 7.8 0.0 4.3 3 2 2 5 5 5 2 Bacterial transcriptional activator domain Rep_fac_C PF08542.6 EIE87110.1 - 0.017 15.0 0.9 5.8 6.9 0.2 3.8 2 1 0 3 3 3 0 Replication factor C C-terminal domain eIF-5a PF01287.15 EIE87110.1 - 0.088 12.7 0.0 4.6 7.2 0.0 2.6 2 0 0 2 2 2 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold RPM2 PF08579.6 EIE87110.1 - 0.1 12.7 10.5 0.25 11.4 0.4 4.5 4 2 1 5 5 5 0 Mitochondrial ribonuclease P subunit (RPM2) MNE1 PF13762.1 EIE87110.1 - 0.15 12.1 7.4 0.58 10.2 0.1 4.3 3 2 1 4 4 4 0 Mitochondrial splicing apparatus component Fungal_trans PF04082.13 EIE87111.1 - 1.1e-29 103.1 6.8 1.9e-29 102.3 4.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain WRKY PF03106.10 EIE87112.1 - 1e-06 28.4 2.3 2.2e-06 27.3 1.6 1.6 1 0 0 1 1 1 1 WRKY DNA -binding domain FLYWCH PF04500.11 EIE87112.1 - 0.041 13.7 0.3 0.041 13.7 0.2 2.0 2 0 0 2 2 2 0 FLYWCH zinc finger domain Flu_NS2 PF00601.14 EIE87112.1 - 0.12 12.5 0.8 0.21 11.8 0.2 1.6 2 0 0 2 2 2 0 Influenza non-structural protein (NS2) Zn_ribbon_recom PF13408.1 EIE87112.1 - 0.16 12.2 2.9 0.38 11.0 2.0 1.6 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain zf-C2H2 PF00096.21 EIE87113.1 - 7.4e-15 54.3 18.7 3.4e-06 27.0 1.3 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIE87113.1 - 1.3e-14 53.6 10.5 1.5e-08 34.5 0.2 4.2 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EIE87113.1 - 7.4e-13 47.8 16.6 0.00012 22.1 0.1 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EIE87113.1 - 0.0003 20.8 5.5 0.28 11.3 0.1 3.4 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding LIM PF00412.17 EIE87113.1 - 0.022 14.8 1.2 0.05 13.6 0.8 1.6 1 0 0 1 1 1 0 LIM domain RRN7 PF11781.3 EIE87113.1 - 0.064 12.7 1.5 0.092 12.2 0.2 1.9 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-C2HC_2 PF13913.1 EIE87113.1 - 0.066 12.8 8.2 0.45 10.2 0.4 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-met PF12874.2 EIE87113.1 - 0.077 13.2 7.7 1.6 9.0 0.1 3.4 4 0 0 4 4 3 0 Zinc-finger of C2H2 type zf-CHY PF05495.7 EIE87113.1 - 0.23 11.6 4.7 0.33 11.1 2.6 1.7 1 1 0 1 1 1 0 CHY zinc finger zf-C2H2_6 PF13912.1 EIE87113.1 - 0.4 10.6 9.6 5.3 7.0 0.4 3.6 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EIE87113.1 - 0.5 10.4 5.3 0.47 10.5 0.3 2.8 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-AN1 PF01428.11 EIE87113.1 - 3.3 7.6 10.0 2.5 8.0 1.7 2.8 1 1 1 2 2 2 0 AN1-like Zinc finger IBR PF01485.16 EIE87113.1 - 7.3 6.5 7.8 3.9 7.4 3.5 2.0 1 1 0 1 1 1 0 IBR domain zf-ZPR1 PF03367.8 EIE87114.1 - 0.039 13.1 0.2 0.046 12.8 0.1 1.3 1 0 0 1 1 1 0 ZPR1 zinc-finger domain IBN_N PF03810.14 EIE87114.1 - 0.71 9.8 4.5 3.2 7.7 0.9 2.4 1 1 1 2 2 2 0 Importin-beta N-terminal domain PPR_2 PF13041.1 EIE87115.1 - 8.4e-45 150.5 6.7 2.6e-08 33.7 0.1 9.9 3 2 8 11 11 11 9 PPR repeat family PPR_3 PF13812.1 EIE87115.1 - 1.9e-33 111.9 0.6 7.4e-06 25.8 0.0 10.2 11 0 0 11 11 11 6 Pentatricopeptide repeat domain PPR PF01535.15 EIE87115.1 - 2.3e-21 74.2 12.8 0.0075 16.1 0.0 11.1 11 1 0 11 11 11 6 PPR repeat PPR_1 PF12854.2 EIE87115.1 - 1.9e-11 43.2 12.9 0.17 11.3 0.0 8.7 9 2 0 9 9 9 5 PPR repeat ECSIT PF06239.6 EIE87115.1 - 7.3e-08 31.5 1.2 0.019 13.8 0.1 4.9 3 2 0 3 3 3 2 Evolutionarily conserved signalling intermediate in Toll pathway NETI PF14044.1 EIE87115.1 - 0.0022 17.4 0.2 0.028 13.9 0.0 2.7 3 0 0 3 3 3 1 NETI protein Utp21 PF04192.7 EIE87115.1 - 0.056 12.5 0.7 4 6.4 0.0 2.9 3 0 0 3 3 3 0 Utp21 specific WD40 associated putative domain DUF217 PF02697.9 EIE87115.1 - 0.1 12.8 4.6 4.7 7.5 0.1 4.1 4 0 0 4 4 4 0 Uncharacterized ACR, COG1753 DDE_3 PF13358.1 EIE87116.1 - 5.1e-06 26.2 0.1 8.5e-06 25.5 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease MIS13 PF08202.6 EIE87116.1 - 0.017 14.1 0.7 0.019 14.0 0.5 1.0 1 0 0 1 1 1 0 Mis12-Mtw1 protein family 2H-phosphodiest PF08975.5 EIE87116.1 - 0.045 13.4 0.1 0.053 13.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1868) SUV3_C PF12513.3 EIE87116.1 - 0.054 12.9 0.1 6.8 6.2 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial degradasome RNA helicase subunit C terminal RRM_1 PF00076.17 EIE87117.1 - 0.11 12.1 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fasciclin PF02469.17 EIE87118.1 - 6.5e-15 55.2 0.3 8e-15 54.9 0.2 1.1 1 0 0 1 1 1 1 Fasciclin domain Copper-fist PF00649.13 EIE87119.1 - 6.4e-15 54.0 0.5 6.4e-15 54.0 0.4 2.1 2 1 0 2 2 2 1 Copper fist DNA binding domain C1_1 PF00130.17 EIE87119.1 - 0.41 10.4 6.9 0.8 9.4 4.8 1.5 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) RhoGAP PF00620.22 EIE87120.1 - 2e-49 167.1 0.2 4.6e-49 165.9 0.2 1.6 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 EIE87120.1 - 2.9e-16 59.2 34.0 8.7e-10 38.5 6.0 3.3 3 0 0 3 3 3 2 LIM domain C1_1 PF00130.17 EIE87120.1 - 1e-07 31.5 1.9 1e-07 31.5 1.3 4.3 2 1 2 4 4 4 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-LITAF-like PF10601.4 EIE87121.1 - 6.3e-17 61.2 4.8 8.6e-17 60.7 3.4 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 EIE87121.1 - 0.0046 16.7 0.5 2.6 7.9 0.0 2.2 2 0 0 2 2 2 2 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.5 EIE87121.1 - 0.0068 16.3 0.1 5.4 7.0 0.0 2.3 2 0 0 2 2 2 2 Zinc ribbon domain Cys_rich_CPXG PF14255.1 EIE87121.1 - 0.02 14.7 1.8 0.039 13.7 0.3 2.0 2 0 0 2 2 2 0 Cysteine-rich CPXCG DUF164 PF02591.10 EIE87121.1 - 0.026 14.3 0.4 0.38 10.6 0.0 2.3 2 0 0 2 2 2 0 Putative zinc ribbon domain UPF0547 PF10571.4 EIE87121.1 - 0.026 14.2 1.8 2.3 7.9 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Exostosin PF03016.10 EIE87121.1 - 0.03 13.3 0.9 0.043 12.8 0.6 1.2 1 0 0 1 1 1 0 Exostosin family zf-RING_3 PF14369.1 EIE87121.1 - 0.047 13.7 1.0 6.1 6.9 0.1 2.5 2 0 0 2 2 2 0 zinc-finger zf-FCS PF06467.9 EIE87121.1 - 0.047 13.3 1.1 7.4 6.3 0.0 2.4 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif Integrase_Zn PF02022.14 EIE87121.1 - 0.074 12.5 5.3 0.2 11.1 0.2 2.7 3 0 0 3 3 3 0 Integrase Zinc binding domain zf-ribbon_3 PF13248.1 EIE87121.1 - 0.075 12.2 0.9 8.7 5.6 0.0 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-TFIIB PF13453.1 EIE87121.1 - 0.087 12.0 0.3 3.9 6.7 0.0 2.3 2 0 0 2 2 2 0 Transcription factor zinc-finger C1_4 PF07975.7 EIE87121.1 - 0.11 12.5 0.9 8.6 6.4 0.0 2.4 2 0 0 2 2 2 0 TFIIH C1-like domain zinc_ribbon_5 PF13719.1 EIE87121.1 - 0.11 12.1 3.7 0.9 9.1 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EIE87121.1 - 0.12 12.0 3.0 1.4 8.7 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-CSL PF05207.8 EIE87121.1 - 0.14 11.6 0.4 2.3 7.8 0.0 2.2 2 0 0 2 2 2 0 CSL zinc finger TFIIS_C PF01096.13 EIE87121.1 - 0.2 11.2 2.1 4.1 7.1 0.1 2.3 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) DNA_ligase_ZBD PF03119.11 EIE87121.1 - 1.1 9.0 3.9 2.1 8.0 0.1 2.3 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain Ogr_Delta PF04606.7 EIE87121.1 - 4.4 7.0 5.8 5.3 6.7 0.2 2.3 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger ALMT PF11744.3 EIE87122.1 - 2.1e-19 69.5 9.3 7.4e-13 47.9 0.7 2.4 2 0 0 2 2 2 2 Aluminium activated malate transporter FUSC_2 PF13515.1 EIE87122.1 - 1.7e-16 60.3 10.3 1.7e-16 60.3 7.1 2.8 2 1 0 2 2 2 1 Fusaric acid resistance protein-like DUF2421 PF10334.4 EIE87122.1 - 5.1e-15 55.7 0.4 1.7e-14 54.0 0.3 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF2421) FUSC PF04632.7 EIE87122.1 - 5.2e-14 51.6 13.1 4.3e-12 45.2 1.8 2.2 2 0 0 2 2 2 2 Fusaric acid resistance protein family DUF2422 PF10337.4 EIE87122.1 - 2.9e-07 29.6 25.2 5.8e-07 28.6 0.5 3.5 2 1 1 3 3 3 2 Protein of unknown function (DUF2422) DUF2730 PF10805.3 EIE87123.1 - 0.014 15.1 0.6 0.046 13.4 0.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) TMF_TATA_bd PF12325.3 EIE87123.1 - 0.099 12.3 5.5 0.62 9.7 3.7 2.3 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding BRICHOS PF04089.9 EIE87123.1 - 0.14 12.0 0.8 0.62 9.9 0.0 2.4 2 1 0 2 2 2 0 BRICHOS domain IncA PF04156.9 EIE87123.1 - 6.7 6.2 7.7 1 8.9 1.8 1.9 2 0 0 2 2 2 0 IncA protein Adap_comp_sub PF00928.16 EIE87124.1 - 2.9e-91 305.2 0.1 3.6e-91 304.8 0.1 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EIE87124.1 - 5e-06 26.2 0.6 1.1e-05 25.2 0.4 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Ras PF00071.17 EIE87125.1 - 7.4e-59 197.7 0.1 8.9e-59 197.4 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIE87125.1 - 1.5e-20 73.8 0.1 1.9e-19 70.2 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EIE87125.1 - 9.9e-18 63.9 0.0 1.3e-17 63.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EIE87125.1 - 4.7e-10 39.0 0.0 5.7e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EIE87125.1 - 3.4e-07 29.8 0.0 5.4e-07 29.2 0.0 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EIE87125.1 - 2.7e-05 24.0 0.0 7.9e-05 22.5 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EIE87125.1 - 0.022 14.7 0.1 0.042 13.8 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain DUF258 PF03193.11 EIE87125.1 - 0.035 13.2 0.5 0.2 10.8 0.1 2.1 2 1 0 2 2 2 0 Protein of unknown function, DUF258 G-alpha PF00503.15 EIE87125.1 - 0.14 10.8 1.1 2.7 6.5 0.1 2.6 1 1 1 3 3 3 0 G-protein alpha subunit Ank_4 PF13637.1 EIE87126.1 - 3.6e-15 56.0 0.6 2.2e-07 31.1 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EIE87126.1 - 5.1e-15 55.5 3.5 1.7e-06 28.2 0.0 2.8 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 EIE87126.1 - 8.9e-14 50.5 0.1 1e-05 25.0 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.1 EIE87126.1 - 2.3e-13 48.9 0.3 0.00022 21.1 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EIE87126.1 - 1.1e-11 44.5 0.2 7e-05 22.9 0.0 3.1 2 1 0 2 2 2 2 Ankyrin repeats (many copies) KilA-N PF04383.8 EIE87126.1 - 2.7e-05 23.7 1.9 0.00012 21.6 0.0 3.0 2 1 0 2 2 2 1 KilA-N domain DUF543 PF04418.7 EIE87127.1 - 1.3e-15 57.1 0.1 1.6e-15 56.8 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) 2TM PF13239.1 EIE87127.1 - 0.00093 19.2 0.0 0.0012 18.8 0.0 1.1 1 0 0 1 1 1 1 2TM domain Sarcoglycan_1 PF04790.8 EIE87128.1 - 0.11 11.6 10.1 0.15 11.1 6.3 1.7 1 1 0 1 1 1 0 Sarcoglycan complex subunit protein Proteasome PF00227.21 EIE87129.1 - 1.3e-50 171.3 0.4 7.7e-37 126.4 0.1 2.2 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 EIE87129.1 - 2.1e-15 55.6 0.1 3.7e-15 54.9 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Cofilin_ADF PF00241.15 EIE87130.1 - 2.9e-40 137.0 0.8 3.3e-40 136.9 0.5 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein GrpE PF01025.14 EIE87131.1 - 0.0013 18.2 10.1 0.002 17.6 7.0 1.3 1 0 0 1 1 1 1 GrpE Med3 PF11593.3 EIE87131.1 - 0.028 13.6 5.2 0.033 13.4 3.6 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal CPT PF07931.7 EIE87131.1 - 0.2 11.2 0.9 0.37 10.3 0.1 1.7 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein SprA-related PF12118.3 EIE87131.1 - 2.9 7.1 22.7 3.5 6.8 15.7 1.0 1 0 0 1 1 1 0 SprA-related family DUF2201_N PF13203.1 EIE87131.1 - 4.9 6.2 9.9 6.2 5.8 6.9 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF936 PF06075.7 EIE87131.1 - 6.6 5.5 18.9 8 5.2 13.1 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) DUF2874 PF11396.3 EIE87132.1 - 0.05 13.5 0.0 0.062 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2874) Trns_repr_metal PF02583.12 EIE87132.1 - 0.066 13.4 0.2 0.088 13.0 0.1 1.2 1 0 0 1 1 1 0 Metal-sensitive transcriptional repressor RNA_pol_Rpc34 PF05158.7 EIE87134.1 - 1.6e-71 241.1 0.4 2.2e-71 240.7 0.3 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit SMC_Nse1 PF07574.8 EIE87134.1 - 0.0014 18.2 0.3 0.0036 16.9 0.1 1.9 1 1 1 2 2 2 1 Nse1 non-SMC component of SMC5-6 complex B-block_TFIIIC PF04182.7 EIE87134.1 - 0.012 15.4 0.1 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC HTH_36 PF13730.1 EIE87134.1 - 0.035 14.2 0.4 0.13 12.3 0.2 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain WAC_Acf1_DNA_bd PF10537.4 EIE87134.1 - 0.074 13.2 0.0 0.55 10.4 0.0 2.3 2 0 0 2 2 2 0 ATP-utilising chromatin assembly and remodelling N-terminal HxlR PF01638.12 EIE87134.1 - 0.091 12.4 0.1 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 HxlR-like helix-turn-helix RPA_C PF08784.6 EIE87134.1 - 0.095 13.1 0.9 1.1 9.6 0.2 2.4 2 0 0 2 2 2 0 Replication protein A C terminal Peptidase_C54 PF03416.14 EIE87136.1 - 4.4e-27 94.9 0.1 6.9e-27 94.2 0.1 1.3 1 0 0 1 1 1 1 Peptidase family C54 RPE65 PF03055.10 EIE87137.1 - 2.2e-68 231.0 0.1 3.6e-66 223.7 0.1 2.0 1 1 0 1 1 1 1 Retinal pigment epithelial membrane protein KH_4 PF13083.1 EIE87138.1 - 0.032 13.8 0.1 0.034 13.7 0.1 1.1 1 0 0 1 1 1 0 KH domain Pkinase PF00069.20 EIE87140.1 - 1.4e-61 207.9 0.0 1.8e-61 207.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE87140.1 - 7.6e-32 110.4 0.0 1.1e-31 109.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE87140.1 - 1.7e-06 27.1 0.0 2.9e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_C PF00433.19 EIE87140.1 - 8.6e-06 26.1 1.3 2.2e-05 24.8 0.0 2.5 2 0 0 2 2 2 1 Protein kinase C terminal domain APH PF01636.18 EIE87140.1 - 0.00031 20.5 0.2 0.011 15.4 0.2 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family PX PF00787.19 EIE87140.1 - 0.015 15.0 2.7 0.037 13.8 1.9 1.7 1 0 0 1 1 1 0 PX domain Peptidase_S8 PF00082.17 EIE87141.1 - 2.2e-54 184.5 4.0 2.2e-54 184.5 2.8 1.4 2 0 0 2 2 2 1 Subtilase family Inhibitor_I9 PF05922.11 EIE87141.1 - 7.5e-17 61.6 0.3 1.7e-16 60.5 0.2 1.7 1 0 0 1 1 1 1 Peptidase inhibitor I9 Ank_2 PF12796.2 EIE87142.1 - 3.5e-31 107.3 9.0 1.7e-10 41.0 0.1 4.1 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EIE87142.1 - 1.3e-17 62.6 9.3 1.1e-05 25.0 0.1 5.8 5 1 1 6 6 6 5 Ankyrin repeat Ank_4 PF13637.1 EIE87142.1 - 2.3e-14 53.4 3.8 3.9e-07 30.4 0.1 5.6 2 2 4 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EIE87142.1 - 1.4e-13 50.5 5.6 2.4e-09 37.1 0.2 5.0 3 2 3 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIE87142.1 - 5.4e-12 44.7 5.8 0.018 15.2 0.0 5.9 5 2 1 6 6 6 3 Ankyrin repeat Pkinase PF00069.20 EIE87143.1 - 3.1e-38 131.4 0.0 3.5e-38 131.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE87143.1 - 2.9e-18 65.8 0.0 3.5e-18 65.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE87143.1 - 1.8e-06 27.1 0.0 2.2e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EIE87143.1 - 0.0076 15.1 0.0 0.0093 14.8 0.0 1.1 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.18 EIE87143.1 - 0.0098 15.6 0.0 0.012 15.3 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EIE87143.1 - 0.06 12.3 0.0 0.073 12.1 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MCR_beta PF02241.13 EIE87143.1 - 0.095 11.8 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Methyl-coenzyme M reductase beta subunit, C-terminal domain YrbL-PhoP_reg PF10707.4 EIE87143.1 - 0.11 11.8 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Cys_Met_Meta_PP PF01053.15 EIE87144.1 - 3.3e-39 134.2 0.0 4.7e-39 133.7 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EIE87144.1 - 0.062 12.2 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II Gly-zipper_Omp PF13488.1 EIE87146.1 - 0.038 13.6 5.7 0.095 12.3 4.0 1.6 1 0 0 1 1 1 0 Glycine zipper Beta-APP PF03494.8 EIE87146.1 - 0.2 11.1 4.0 0.37 10.2 2.8 1.4 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) Acetyltransf_1 PF00583.19 EIE87147.1 - 2.4e-09 37.0 0.0 3.1e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EIE87147.1 - 0.00029 20.5 0.0 0.00039 20.1 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 EIE87147.1 - 0.00051 20.1 0.0 0.00066 19.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3958 PF13125.1 EIE87147.1 - 0.024 14.5 0.0 0.033 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3958) FUN14 PF04930.10 EIE87148.1 - 0.00032 20.9 0.1 0.00037 20.7 0.0 1.2 1 0 0 1 1 1 1 FUN14 family Toxin_56 PF15534.1 EIE87148.1 - 0.004 17.6 0.0 0.0055 17.1 0.0 1.2 1 0 0 1 1 1 1 Putative toxin 56 NADPH_Ox PF08414.5 EIE87148.1 - 0.0087 16.1 0.0 0.012 15.6 0.0 1.2 1 0 0 1 1 1 1 Respiratory burst NADPH oxidase DUF679 PF05078.7 EIE87148.1 - 0.076 12.6 0.0 0.081 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF679) AAA_29 PF13555.1 EIE87148.1 - 0.084 12.4 0.6 7.2 6.2 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain TPR_11 PF13414.1 EIE87149.1 - 3.7e-13 48.9 0.2 1e-09 37.9 0.1 2.3 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 EIE87149.1 - 1.3e-08 34.1 0.1 0.056 13.3 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 EIE87149.1 - 8.1e-08 31.5 0.0 0.032 13.8 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EIE87149.1 - 0.023 14.6 0.2 7.8 6.5 0.0 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 EIE87149.1 - 0.029 14.1 0.0 9.8 6.2 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1237 PF06824.6 EIE87150.1 - 3.4e-98 329.0 0.0 4.2e-98 328.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) Gly_transf_sug PF04488.10 EIE87151.1 - 1.3e-09 38.3 0.0 3.9e-09 36.8 0.0 1.8 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Laminin_G_3 PF13385.1 EIE87151.1 - 2.8e-07 30.8 0.1 4.6e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily TcdA_TcdB PF12919.2 EIE87151.1 - 0.00028 19.5 0.0 0.00045 18.8 0.0 1.2 1 0 0 1 1 1 1 TcdA/TcdB catalytic glycosyltransferase domain Caps_synth PF05704.7 EIE87151.1 - 0.0067 15.6 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein RNA_pol_Rpb4 PF03874.11 EIE87152.1 - 1.5e-17 63.6 0.4 1.9e-17 63.3 0.3 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 UBACT PF02134.16 EIE87152.1 - 0.048 13.2 0.1 0.083 12.4 0.1 1.4 1 0 0 1 1 1 0 Repeat in ubiquitin-activating (UBA) protein IL15 PF02372.10 EIE87152.1 - 0.21 11.3 1.6 1.3 8.8 0.0 2.0 1 1 1 2 2 2 0 Interleukin 15 DUF155 PF02582.9 EIE87153.1 - 0.0024 17.8 0.1 0.0048 16.8 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Lipocalin_6 PF13944.1 EIE87153.1 - 0.24 11.5 0.0 0.24 11.5 0.0 2.4 4 0 0 4 4 4 0 Lipocalin-like domain ParG PF09274.5 EIE87154.1 - 0.098 12.5 2.1 0.13 12.1 0.3 1.9 2 0 0 2 2 2 0 ParG BAF1_ABF1 PF04684.8 EIE87154.1 - 0.13 11.1 13.9 0.19 10.5 9.7 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Serinc PF03348.10 EIE87154.1 - 0.2 10.3 3.2 0.24 10.0 2.2 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) FAM176 PF14851.1 EIE87154.1 - 0.59 9.8 9.0 0.11 12.1 3.9 1.6 2 0 0 2 2 2 0 FAM176 family SID-1_RNA_chan PF13965.1 EIE87154.1 - 0.9 7.6 3.9 0.95 7.5 2.7 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 OmpH PF03938.9 EIE87154.1 - 3.1 7.7 20.1 4.4 7.2 13.9 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF3439 PF11921.3 EIE87154.1 - 3.2 7.5 8.2 2.2 8.0 4.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) TFIIA PF03153.8 EIE87154.1 - 5 6.9 28.0 5.8 6.7 19.4 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.3 EIE87154.1 - 5.7 6.2 13.3 0.26 10.6 3.1 2.3 2 0 0 2 2 2 0 Spt20 family DUF775 PF05603.7 EIE87154.1 - 7.3 6.0 11.9 0.82 9.1 3.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF775) MMR_HSR1 PF01926.18 EIE87156.1 - 0.025 14.5 0.0 0.025 14.5 0.0 1.1 1 0 0 1 1 1 0 50S ribosome-binding GTPase bZIP_2 PF07716.10 EIE87157.1 - 3.1e-10 39.7 5.2 3.1e-10 39.7 3.6 3.9 3 1 2 5 5 5 1 Basic region leucine zipper bZIP_1 PF00170.16 EIE87157.1 - 1.9e-08 34.1 10.1 1.9e-08 34.1 7.0 2.9 2 1 0 2 2 2 1 bZIP transcription factor Nucleoplasmin PF03066.10 EIE87157.1 - 0.0012 18.3 19.8 0.0081 15.6 5.9 2.8 2 0 0 2 2 2 2 Nucleoplasmin CENP-B_dimeris PF09026.5 EIE87157.1 - 5.5 7.2 30.0 1.1 9.4 11.0 2.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain PGAP1 PF07819.8 EIE87158.1 - 0.012 15.1 0.0 0.017 14.7 0.0 1.3 1 1 0 1 1 1 0 PGAP1-like protein A_deaminase PF00962.17 EIE87159.1 - 5.4e-115 383.8 0.0 7.8e-115 383.3 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase TAFII55_N PF04658.8 EIE87160.1 - 1e-41 142.1 0.4 1e-41 142.1 0.3 2.1 2 1 0 2 2 2 1 TAFII55 protein conserved region SURF2 PF05477.6 EIE87160.1 - 0.033 13.3 13.4 0.055 12.5 9.3 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) CDC27 PF09507.5 EIE87160.1 - 0.15 11.2 23.6 0.19 10.9 16.3 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CENP-T PF15511.1 EIE87160.1 - 0.19 10.9 18.3 0.22 10.7 12.7 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Hom_end_hint PF05203.11 EIE87160.1 - 0.19 11.4 5.2 0.3 10.7 3.6 1.3 1 0 0 1 1 1 0 Hom_end-associated Hint Nop14 PF04147.7 EIE87160.1 - 0.33 8.8 31.9 0.42 8.4 22.1 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 EIE87160.1 - 0.87 7.5 22.6 1.2 7.1 15.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Atg14 PF10186.4 EIE87160.1 - 3 6.7 10.2 0.29 10.0 2.4 2.0 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 BUD22 PF09073.5 EIE87160.1 - 4.8 6.1 30.1 8.2 5.3 20.9 1.4 1 1 0 1 1 1 0 BUD22 Daxx PF03344.10 EIE87160.1 - 7 5.0 27.0 9.9 4.5 18.7 1.3 1 0 0 1 1 1 0 Daxx Family RdRP PF05183.7 EIE87161.1 - 2e-124 416.4 0.1 3.2e-124 415.7 0.1 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase Pkinase PF00069.20 EIE87163.1 - 4.5e-15 55.5 1.5 8e-15 54.6 0.0 2.2 2 2 0 2 2 2 1 Protein kinase domain Choline_kinase PF01633.15 EIE87163.1 - 0.0024 17.4 0.5 0.0024 17.4 0.3 2.5 3 0 0 3 3 3 1 Choline/ethanolamine kinase EcKinase PF02958.15 EIE87163.1 - 0.014 14.5 0.3 0.014 14.5 0.2 1.9 2 0 0 2 2 2 0 Ecdysteroid kinase APH PF01636.18 EIE87163.1 - 0.11 12.1 0.9 0.3 10.7 0.6 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family YqfD PF06898.6 EIE87163.1 - 0.12 11.0 6.3 0.18 10.4 4.4 1.2 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD Adap_comp_sub PF00928.16 EIE87164.1 - 1.9e-06 27.1 0.1 2.5e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EIE87164.1 - 0.011 15.4 0.1 0.021 14.5 0.0 1.5 2 0 0 2 2 2 0 Clathrin adaptor complex small chain ZZ PF00569.12 EIE87165.1 - 4.7e-09 35.6 2.5 7.7e-09 34.9 1.7 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.26 EIE87165.1 - 1.9e-08 34.1 0.0 4.1e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EIE87165.1 - 9.5e-06 25.6 0.0 2.6e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF3795 PF12675.2 EIE87165.1 - 0.21 11.8 2.4 0.4 10.9 1.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3795) C1_3 PF07649.7 EIE87165.1 - 0.73 9.9 4.3 0.49 10.4 1.5 1.9 2 0 0 2 2 2 0 C1-like domain Pkinase PF00069.20 EIE87166.1 - 1.4e-46 158.8 0.0 1.6e-46 158.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE87166.1 - 3.6e-21 75.3 0.0 4.6e-21 75.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE87166.1 - 4.3e-07 29.1 0.0 5.5e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EIE87166.1 - 0.0037 16.3 0.0 0.0055 15.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L6 PF00347.18 EIE87167.1 - 1.1e-29 102.7 7.9 2e-17 63.4 2.6 2.0 2 0 0 2 2 2 2 Ribosomal protein L6 FAT PF02259.18 EIE87168.1 - 1.2e-122 409.3 1.1 1.2e-122 409.3 0.8 2.4 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.22 EIE87168.1 - 9.7e-61 205.2 0.7 1.9e-60 204.2 0.5 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.3 EIE87168.1 - 6.2e-57 191.9 4.9 1.7e-55 187.3 0.1 4.5 5 0 0 5 5 5 1 Domain of unknown function (DUF3385) Rapamycin_bind PF08771.6 EIE87168.1 - 7.8e-43 144.6 1.2 7.8e-43 144.6 0.8 3.2 3 0 0 3 3 3 1 Rapamycin binding domain FATC PF02260.15 EIE87168.1 - 3.1e-16 58.4 0.4 9.7e-16 56.9 0.3 1.9 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.1 EIE87168.1 - 3.6e-15 56.0 8.9 0.023 14.9 0.0 9.7 5 3 4 9 9 9 3 HEAT repeats HEAT PF02985.17 EIE87168.1 - 7.6e-14 50.4 20.6 0.006 16.5 0.0 10.1 10 0 0 10 10 8 3 HEAT repeat HEAT_EZ PF13513.1 EIE87168.1 - 4.2e-12 46.1 26.3 4.4e-06 27.0 0.2 11.3 10 2 3 13 13 11 4 HEAT-like repeat TPR_16 PF13432.1 EIE87168.1 - 4.1e-08 33.6 0.1 0.36 11.5 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 EIE87168.1 - 6.5e-07 29.6 0.0 0.02 15.2 0.1 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat Vac14_Fab1_bd PF12755.2 EIE87168.1 - 1.6e-05 25.1 2.4 10 6.5 0.0 7.4 6 2 1 7 7 7 0 Vacuolar 14 Fab1-binding region TPR_12 PF13424.1 EIE87168.1 - 0.00052 19.8 1.0 2.2 8.2 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat Apc3 PF12895.2 EIE87168.1 - 0.00068 19.7 0.3 0.82 9.8 0.0 3.8 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 Baculo_PEP_C PF04513.7 EIE87168.1 - 0.0038 17.0 0.1 0.11 12.2 0.0 3.0 3 0 0 3 3 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus TPR_11 PF13414.1 EIE87168.1 - 0.0078 15.8 2.9 3.1 7.4 0.1 4.6 4 0 0 4 4 4 1 TPR repeat TPR_2 PF07719.12 EIE87168.1 - 0.013 15.3 4.7 11 6.2 0.2 4.4 3 0 0 3 3 3 0 Tetratricopeptide repeat ParcG PF10274.4 EIE87168.1 - 2 8.2 8.8 0.64 9.9 0.2 3.9 4 1 1 5 5 4 0 Parkin co-regulated protein Glyco_hydro_9 PF00759.14 EIE87169.1 - 2.8e-51 174.8 5.9 3.5e-51 174.4 4.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 SKG6 PF08693.5 EIE87169.1 - 0.0082 15.4 0.7 0.018 14.3 0.5 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain SIT PF15330.1 EIE87169.1 - 0.013 15.6 0.2 1.5 8.9 0.0 2.6 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT TMEM154 PF15102.1 EIE87169.1 - 0.04 13.6 0.0 0.083 12.5 0.0 1.6 1 0 0 1 1 1 0 TMEM154 protein family DUF4316 PF14195.1 EIE87169.1 - 0.074 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4316) Endonuclease_NS PF01223.18 EIE87170.1 - 3.5e-55 186.8 0.0 4.4e-55 186.5 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease CotH PF08757.6 EIE87171.1 - 1.9e-28 99.6 6.4 1.9e-28 99.6 4.5 1.5 2 0 0 2 2 2 1 CotH protein DUF1325 PF07039.6 EIE87172.1 - 4e-21 74.9 0.5 4.3e-21 74.8 0.3 1.0 1 0 0 1 1 1 1 SGF29 tudor-like domain TUDOR PF00567.19 EIE87172.1 - 0.0098 15.7 0.0 0.011 15.5 0.0 1.0 1 0 0 1 1 1 1 Tudor domain DUF4537 PF15057.1 EIE87172.1 - 0.012 15.3 0.0 0.015 15.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) Agenet PF05641.7 EIE87172.1 - 0.026 14.6 0.0 0.035 14.2 0.0 1.2 1 0 0 1 1 1 0 Agenet domain PINIT PF14324.1 EIE87173.1 - 2.9e-23 82.5 0.4 3.5e-23 82.2 0.3 1.1 1 0 0 1 1 1 1 PINIT domain EF-hand_4 PF12763.2 EIE87174.1 - 3.8e-33 113.3 0.0 2.7e-28 97.7 0.0 2.4 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand End3 PF12761.2 EIE87174.1 - 2.2e-25 89.4 4.5 3.5e-25 88.7 3.1 1.3 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_1 PF00036.27 EIE87174.1 - 5.9e-06 25.2 0.4 2.6e-05 23.2 0.2 2.1 2 0 0 2 2 2 1 EF hand DUF1720 PF08226.6 EIE87174.1 - 1.2e-05 25.2 53.5 0.096 12.7 37.0 3.1 1 1 0 1 1 1 1 Domain of unknown function (DUF1720) EF-hand_8 PF13833.1 EIE87174.1 - 0.0006 19.3 0.0 0.0018 17.8 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.1 EIE87174.1 - 0.0006 19.8 0.0 0.013 15.6 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 EIE87174.1 - 0.0035 17.1 1.2 0.22 11.5 0.2 3.1 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.1 EIE87174.1 - 0.059 12.7 0.1 0.21 11.0 0.1 1.9 1 0 0 1 1 1 0 EF hand eIF-4B PF06273.6 EIE87174.1 - 0.13 11.0 8.5 0.25 10.0 5.9 1.4 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B Laminin_II PF06009.7 EIE87174.1 - 0.13 11.9 9.3 0.14 11.8 1.0 2.3 1 1 1 2 2 2 0 Laminin Domain II DUF972 PF06156.8 EIE87174.1 - 0.2 12.0 7.8 0.21 11.9 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) SlyX PF04102.7 EIE87174.1 - 0.29 11.5 7.0 6.6 7.1 0.4 2.7 2 0 0 2 2 2 0 SlyX HisKA PF00512.20 EIE87174.1 - 2.7 8.0 5.9 0.23 11.4 0.7 1.7 2 0 0 2 2 1 0 His Kinase A (phospho-acceptor) domain Fib_alpha PF08702.5 EIE87174.1 - 3.5 7.7 5.6 6.6 6.8 3.9 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Ribosomal_L36e PF01158.13 EIE87175.1 - 3.9e-14 52.3 3.4 4.1e-14 52.3 2.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e PK PF00224.16 EIE87176.1 - 1.3e-165 550.1 4.9 1.7e-165 549.8 3.4 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 EIE87176.1 - 2e-32 111.2 0.1 1.2e-31 108.6 0.0 2.4 3 0 0 3 3 3 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 EIE87176.1 - 3.7e-06 25.9 0.2 7.7e-06 24.9 0.1 1.6 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.20 EIE87176.1 - 0.035 13.0 0.5 0.24 10.2 0.0 2.1 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain Methyltransf_11 PF08241.7 EIE87177.1 - 3.3e-08 33.9 0.0 7.4e-07 29.5 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIE87177.1 - 3.8e-06 26.5 0.0 1.8e-05 24.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIE87177.1 - 3.9e-06 26.6 0.0 7.5e-06 25.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIE87177.1 - 0.047 14.2 0.0 0.23 12.0 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_4 PF02390.12 EIE87177.1 - 0.054 12.5 0.0 0.15 11.0 0.0 1.7 1 0 0 1 1 1 0 Putative methyltransferase WD40 PF00400.27 EIE87178.1 - 4.1e-45 150.1 13.9 2.6e-10 39.7 0.1 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat IRF PF00605.12 EIE87178.1 - 0.47 10.2 4.0 1 9.1 0.6 2.6 1 1 1 3 3 3 0 Interferon regulatory factor transcription factor Arf PF00025.16 EIE87179.1 - 1.2e-16 60.5 0.1 1.2e-16 60.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EIE87179.1 - 0.0027 17.1 0.0 0.0031 16.9 0.0 1.0 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain TPP_enzyme_N PF02776.13 EIE87180.1 - 7.5e-32 110.1 0.0 1.6e-31 109.1 0.0 1.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EIE87180.1 - 2.4e-23 82.4 0.0 4e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EIE87180.1 - 2e-16 59.9 0.4 4.1e-16 58.9 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF362 PF04015.7 EIE87180.1 - 0.088 12.2 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF362) CCD PF07860.6 EIE87182.1 - 0.0049 16.3 0.1 0.006 16.0 0.1 1.3 1 0 0 1 1 1 1 WisP family C-Terminal Region MAPEG PF01124.13 EIE87182.1 - 0.02 14.4 2.6 0.032 13.8 1.8 1.3 1 1 0 1 1 1 0 MAPEG family BRI3BP PF14965.1 EIE87182.1 - 2.2 7.5 8.9 0.036 13.4 1.3 1.6 2 0 0 2 2 2 0 Negative regulator of p53/TP53 E1_dh PF00676.15 EIE87183.1 - 2.7e-92 308.7 0.0 3.1e-92 308.5 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component Transketolase_N PF00456.16 EIE87183.1 - 5.2e-07 28.7 0.0 7e-07 28.3 0.0 1.3 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain DXP_synthase_N PF13292.1 EIE87183.1 - 0.0022 16.9 0.0 0.016 14.1 0.0 2.1 1 1 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.16 EIE87183.1 - 0.0028 17.2 0.1 0.012 15.1 0.0 2.0 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Amidase02_C PF12123.3 EIE87183.1 - 0.1 12.2 0.1 0.21 11.2 0.1 1.5 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase Lon_C PF05362.8 EIE87184.1 - 1.7e-66 223.4 0.0 5.4e-66 221.8 0.0 1.9 2 0 0 2 2 2 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 EIE87184.1 - 2.1e-37 128.7 8.3 3.7e-37 128.0 0.5 3.1 3 1 0 3 3 3 1 ATP-dependent protease La (LON) domain AAA PF00004.24 EIE87184.1 - 3.3e-23 82.3 0.0 1.1e-22 80.6 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EIE87184.1 - 7.1e-07 29.0 0.0 1.4e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EIE87184.1 - 1e-05 25.7 0.1 0.00027 21.0 0.0 2.9 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EIE87184.1 - 8.7e-05 21.6 0.0 0.00063 18.8 0.0 2.6 2 1 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_PrkA PF08298.6 EIE87184.1 - 0.00011 21.0 0.0 0.00021 20.1 0.0 1.3 1 0 0 1 1 1 1 PrkA AAA domain AAA_17 PF13207.1 EIE87184.1 - 0.00024 21.9 0.0 0.0012 19.6 0.0 2.3 2 0 0 2 2 1 1 AAA domain AAA_14 PF13173.1 EIE87184.1 - 0.00099 19.0 0.0 0.0031 17.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EIE87184.1 - 0.0012 18.8 2.5 0.004 17.1 0.1 2.7 3 1 0 3 3 3 1 AAA ATPase domain ChlI PF13541.1 EIE87184.1 - 0.0016 17.9 0.0 0.0037 16.7 0.0 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase NTPase_1 PF03266.10 EIE87184.1 - 0.0038 16.9 0.3 0.14 11.8 0.0 2.9 2 1 1 3 3 2 1 NTPase AAA_18 PF13238.1 EIE87184.1 - 0.0053 17.0 5.2 0.017 15.4 0.0 3.4 4 0 0 4 4 3 1 AAA domain SKI PF01202.17 EIE87184.1 - 0.0088 15.9 0.4 0.066 13.0 0.0 2.4 2 0 0 2 2 2 1 Shikimate kinase ClpB_D2-small PF10431.4 EIE87184.1 - 0.026 14.4 3.1 0.098 12.5 0.0 2.8 3 0 0 3 3 2 0 C-terminal, D2-small domain, of ClpB protein UPF0079 PF02367.12 EIE87184.1 - 0.032 13.8 0.0 0.076 12.6 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_3 PF07726.6 EIE87184.1 - 0.035 13.6 0.0 0.12 12.0 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EIE87184.1 - 0.051 13.3 0.1 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain RNA_helicase PF00910.17 EIE87184.1 - 0.053 13.6 0.0 0.19 11.9 0.0 2.0 1 0 0 1 1 1 0 RNA helicase Phage_connect_1 PF05135.8 EIE87184.1 - 0.063 13.4 2.1 0.73 10.0 0.2 2.6 2 0 0 2 2 2 0 Phage gp6-like head-tail connector protein AA_permease_2 PF13520.1 EIE87187.1 - 3.3e-60 203.8 45.8 4.1e-60 203.5 31.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EIE87187.1 - 1.1e-33 116.3 40.2 1.4e-33 115.9 27.9 1.0 1 0 0 1 1 1 1 Amino acid permease Peptidase_M56 PF05569.6 EIE87187.1 - 0.023 13.6 2.4 0.038 12.9 1.2 1.7 1 1 0 1 1 1 0 BlaR1 peptidase M56 Usp PF00582.21 EIE87188.1 - 2.2e-19 70.0 1.1 2.2e-18 66.7 0.2 2.5 2 1 0 2 2 2 1 Universal stress protein family FAM183 PF14886.1 EIE87188.1 - 0.017 15.6 0.9 0.045 14.2 0.6 1.7 1 0 0 1 1 1 0 FAM183A and FAM183B related Chitin_synth_1 PF01644.12 EIE87189.1 - 5.4e-87 289.6 0.1 7.8e-87 289.1 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EIE87189.1 - 8.5e-32 108.6 0.2 2.8e-31 107.0 0.2 1.8 2 0 0 2 2 2 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EIE87189.1 - 5.3e-20 71.3 7.6 8.1e-19 67.3 0.1 2.3 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 EIE87189.1 - 5.4e-08 32.7 8.6 2.3e-07 30.7 5.5 2.2 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EIE87189.1 - 8.3e-07 29.0 0.0 1.8e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 E1-E2_ATPase PF00122.15 EIE87190.1 - 4.1e-59 199.4 1.2 4.1e-59 199.4 0.8 2.4 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 EIE87190.1 - 1.2e-20 74.8 0.0 3.8e-20 73.2 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EIE87190.1 - 2.9e-14 52.2 0.0 8.5e-14 50.7 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EIE87190.1 - 6.4e-12 46.0 0.1 1.9e-11 44.4 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EIE87190.1 - 1.6e-05 24.6 0.3 3.8e-05 23.4 0.2 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase ORC3_N PF07034.6 EIE87191.1 - 1.6e-41 142.4 0.3 1.6e-41 142.4 0.2 1.9 2 0 0 2 2 2 1 Origin recognition complex (ORC) subunit 3 N-terminus Uds1 PF15456.1 EIE87191.1 - 0.14 12.1 5.7 0.038 13.9 1.4 1.9 2 0 0 2 2 2 0 Up-regulated During Septation BSD PF03909.12 EIE87193.1 - 4.5e-16 58.3 1.0 4.5e-16 58.3 0.7 2.8 3 0 0 3 3 3 1 BSD domain Mad3_BUB1_I PF08311.7 EIE87193.1 - 2.2e-15 56.5 0.2 6.3e-15 55.0 0.1 1.9 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 EF-hand_1 PF00036.27 EIE87194.1 - 6.2e-42 137.7 12.8 2e-10 39.2 0.7 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EIE87194.1 - 2.7e-37 126.7 4.8 4.6e-21 74.7 0.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EIE87194.1 - 1.5e-34 117.3 11.5 9.6e-17 60.3 0.3 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 EIE87194.1 - 1.6e-32 108.4 8.1 1e-09 37.4 0.1 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EIE87194.1 - 5.1e-27 91.9 8.8 9.7e-07 27.8 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 EIE87194.1 - 2.1e-13 49.9 0.1 4.5e-06 26.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 EIE87194.1 - 4.5e-10 39.2 0.9 0.00015 21.4 0.1 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EIE87194.1 - 1e-09 38.4 0.0 3.4e-05 23.8 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EFhand_Ca_insen PF08726.5 EIE87194.1 - 6.8e-07 29.1 3.1 1.3e-05 25.0 0.4 2.4 2 1 0 2 2 2 1 Ca2+ insensitive EF hand UPF0154 PF03672.8 EIE87194.1 - 0.00017 21.1 0.3 0.036 13.6 0.0 3.3 3 1 1 4 4 4 1 Uncharacterised protein family (UPF0154) EF-hand_like PF09279.6 EIE87194.1 - 0.00017 21.5 2.0 0.00097 19.1 0.2 2.6 2 1 1 3 3 3 1 Phosphoinositide-specific phospholipase C, efhand-like TerB PF05099.8 EIE87194.1 - 0.00041 20.0 1.9 0.2 11.4 0.0 2.6 1 1 2 3 3 3 2 Tellurite resistance protein TerB DUF3349 PF11829.3 EIE87194.1 - 0.0015 18.8 0.6 0.77 10.2 0.0 3.0 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) Tenui_NCP PF04876.7 EIE87194.1 - 0.011 15.2 0.3 0.91 9.0 0.0 2.1 1 1 1 2 2 2 0 Tenuivirus major non-capsid protein RNA_pol_Rpb4 PF03874.11 EIE87194.1 - 0.013 15.4 2.7 0.95 9.4 0.2 2.7 3 0 0 3 3 3 0 RNA polymerase Rpb4 DUF853 PF05872.7 EIE87194.1 - 0.018 13.4 0.1 0.14 10.4 0.0 1.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF853) Caleosin PF05042.8 EIE87194.1 - 0.02 14.4 0.1 5.1 6.6 0.0 2.6 1 1 0 2 2 2 0 Caleosin related protein DUF2267 PF10025.4 EIE87194.1 - 0.023 14.7 0.0 0.36 10.8 0.0 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2267) SpoVIF PF14069.1 EIE87194.1 - 0.041 13.6 0.6 1.1 9.0 0.1 2.4 2 0 0 2 2 2 0 Stage VI sporulation protein F OST-HTH PF12872.2 EIE87194.1 - 0.05 13.4 0.1 5.5 6.9 0.0 3.3 2 1 1 3 3 3 0 OST-HTH/LOTUS domain DUF4373 PF14297.1 EIE87194.1 - 0.06 13.6 0.3 1 9.7 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4373) DUF1880 PF08976.6 EIE87194.1 - 0.065 13.3 0.0 4 7.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1880) MotA_activ PF09114.5 EIE87194.1 - 0.1 12.3 0.1 17 5.2 0.0 2.4 2 0 0 2 2 2 0 Transcription factor MotA, activation domain Fe_hyd_lg_C PF02906.9 EIE87194.1 - 0.12 11.5 1.1 0.44 9.7 0.7 1.8 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain CMD PF02627.15 EIE87194.1 - 0.17 11.7 0.6 2.3 8.1 0.0 2.7 3 1 1 4 4 4 0 Carboxymuconolactone decarboxylase family DUF3650 PF12368.3 EIE87194.1 - 0.24 10.8 3.4 39 3.8 0.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3650) Arrestin_C PF02752.17 EIE87195.1 - 0.0085 16.1 2.3 0.013 15.5 1.6 1.3 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain DUF3344 PF11824.3 EIE87195.1 - 0.058 12.7 0.3 0.077 12.3 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3344) Myb_DNA-bind_5 PF13873.1 EIE87195.1 - 0.081 12.8 0.1 0.17 11.7 0.1 1.5 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain bZIP_1 PF00170.16 EIE87196.1 - 0.011 15.6 4.3 0.011 15.6 3.0 7.4 7 1 2 9 9 9 0 bZIP transcription factor Filament PF00038.16 EIE87196.1 - 7 6.0 90.3 0.0069 15.8 10.8 4.2 2 2 1 4 4 4 0 Intermediate filament protein LCAT PF02450.10 EIE87197.1 - 0.034 13.1 0.2 0.061 12.2 0.1 1.4 2 0 0 2 2 2 0 Lecithin:cholesterol acyltransferase DUF972 PF06156.8 EIE87197.1 - 0.037 14.3 1.9 0.037 14.3 1.3 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF972) DUF2216 PF10226.4 EIE87197.1 - 0.6 9.5 8.0 4.1 6.8 0.4 2.2 1 1 1 2 2 2 0 Uncharacterized conserved proteins (DUF2216) DUF4613 PF15390.1 EIE87197.1 - 0.74 7.9 6.0 0.98 7.5 4.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Fib_alpha PF08702.5 EIE87197.1 - 2.9 7.9 9.0 6.2 6.9 6.2 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family PCNA_N PF00705.13 EIE87198.1 - 3.8e-45 152.4 0.4 7.2e-45 151.5 0.3 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 EIE87198.1 - 4.6e-37 126.7 0.2 6.7e-37 126.2 0.1 1.3 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain Rad1 PF02144.11 EIE87198.1 - 4.7e-05 22.2 1.3 0.00026 19.8 0.9 1.9 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.8 EIE87198.1 - 0.0015 17.7 0.1 0.0019 17.3 0.1 1.1 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.7 EIE87198.1 - 0.03 13.2 0.0 0.073 12.0 0.0 1.6 1 1 1 2 2 2 0 Hus1-like protein Glyco_hydro_4 PF02056.11 EIE87198.1 - 0.11 11.8 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase DUF1789 PF08748.6 EIE87199.1 - 0.08 13.0 3.1 0.1 12.6 2.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1789) DUF3576 PF12100.3 EIE87199.1 - 0.14 12.1 0.4 0.25 11.4 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3576) Borrelia_P83 PF05262.6 EIE87199.1 - 0.39 8.9 13.4 0.48 8.6 9.3 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF3952 PF13130.1 EIE87199.1 - 2.2 8.3 7.4 0.42 10.6 2.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3952) Fucose_iso_N2 PF07882.7 EIE87199.1 - 5.7 6.5 8.7 13 5.3 2.6 2.1 1 1 1 2 2 2 0 L-fucose isomerase, second N-terminal domain WTX PF09422.5 EIE87199.1 - 9.1 5.1 12.3 9.8 5.0 8.5 1.0 1 0 0 1 1 1 0 WTX protein DUF1044 PF06296.7 EIE87200.1 - 0.039 13.7 0.1 0.052 13.3 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1044) RAP1 PF07218.6 EIE87201.1 - 0.036 12.1 12.9 0.045 11.8 8.9 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Fer4_21 PF14697.1 EIE87201.1 - 0.087 12.7 0.3 0.16 11.8 0.2 1.4 1 0 0 1 1 1 0 4Fe-4S dicluster domain ASL_C PF08328.6 EIE87202.1 - 0.094 12.5 0.3 0.17 11.7 0.2 1.4 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminal BUD22 PF09073.5 EIE87202.1 - 7.7 5.4 38.8 20 4.0 26.9 1.7 1 1 0 1 1 1 0 BUD22 HAND PF09110.6 EIE87203.1 - 0.14 12.5 5.5 0.18 12.1 3.8 1.1 1 0 0 1 1 1 0 HAND Kazal_2 PF07648.10 EIE87203.1 - 0.48 10.3 0.1 0.48 10.3 0.1 2.1 2 1 0 2 2 2 0 Kazal-type serine protease inhibitor domain GATA PF00320.22 EIE87204.1 - 2e-16 59.0 4.3 2e-16 59.0 3.0 2.3 2 0 0 2 2 2 1 GATA zinc finger Cytochrom_c3_2 PF14537.1 EIE87204.1 - 0.0016 18.7 7.2 0.29 11.5 0.2 2.5 2 0 0 2 2 2 2 Cytochrome c3 Cytochrome_C7 PF14522.1 EIE87204.1 - 0.013 15.0 7.4 1 9.0 0.5 2.6 2 0 0 2 2 2 0 Cytochrome c7 ArfGap PF01412.13 EIE87204.1 - 0.019 14.7 5.1 0.2 11.4 0.1 2.4 1 1 1 2 2 2 0 Putative GTPase activating protein for Arf Cut8_N PF14482.1 EIE87204.1 - 0.034 14.1 2.2 0.83 9.7 0.2 3.0 2 0 0 2 2 2 0 Cut8 proteasome-binding domain DZR PF12773.2 EIE87204.1 - 0.15 11.9 6.8 1.9 8.3 0.8 2.5 2 0 0 2 2 2 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.6 EIE87204.1 - 1.1 8.9 10.5 0.29 10.8 1.0 2.8 2 1 1 3 3 3 0 Putative transposase DNA-binding domain LIM PF00412.17 EIE87204.1 - 1.4 9.0 8.3 7.1 6.7 0.2 2.5 2 0 0 2 2 2 0 LIM domain TF_Zn_Ribbon PF08271.7 EIE87204.1 - 3.7 6.9 5.5 1.4 8.3 0.1 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding DUF3133 PF11331.3 EIE87205.1 - 0.035 13.6 0.0 0.056 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3133) PUCC PF03209.10 EIE87207.1 - 0.00046 19.0 0.0 0.0005 18.9 0.0 1.1 1 0 0 1 1 1 1 PUCC protein ETF_QO PF05187.8 EIE87207.1 - 0.061 13.3 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 Electron transfer flavoprotein-ubiquinone oxidoreductase Malate_synthase PF01274.17 EIE87208.1 - 0.12 10.3 0.0 0.14 10.1 0.0 1.0 1 0 0 1 1 1 0 Malate synthase Glyco_hydro_47 PF01532.15 EIE87209.1 - 1.9e-155 517.9 0.3 2.3e-155 517.7 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 M20_dimer PF07687.9 EIE87210.1 - 9.3e-11 41.4 0.1 2.7e-10 39.9 0.0 1.8 1 0 0 1 1 1 1 Peptidase dimerisation domain zf-MIZ PF02891.15 EIE87211.1 - 3.9e-13 48.7 2.2 7.7e-13 47.7 1.5 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 EIE87211.1 - 0.00014 21.2 2.0 0.00036 19.9 1.4 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit DUF4497 PF14924.1 EIE87211.1 - 0.079 13.2 0.1 0.22 11.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4497) zf-C3HC4_2 PF13923.1 EIE87211.1 - 0.34 10.9 2.7 1 9.4 1.9 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Cwf_Cwc_15 PF04889.7 EIE87213.1 - 0.5 10.0 31.9 0.75 9.4 22.1 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CT47 PF15623.1 EIE87213.1 - 1 9.0 38.7 1.2 8.8 26.9 1.0 1 0 0 1 1 1 0 Cancer/testis gene family 47 SpoIIIAH PF12685.2 EIE87213.1 - 2.6 7.4 20.1 28 4.1 13.9 2.1 1 1 0 1 1 1 0 SpoIIIAH-like protein Peptidase_C37 PF05416.7 EIE87213.1 - 4.5 5.4 12.1 8.8 4.4 8.4 1.5 1 1 0 1 1 1 0 Southampton virus-type processing peptidase GAGA_bind PF06217.7 EIE87213.1 - 8.5 6.2 12.4 10 5.9 8.6 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family DUF641 PF04859.7 EIE87214.1 - 0.017 14.9 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) HSA PF07529.8 EIE87215.1 - 0.11 12.3 1.4 2.9 7.7 0.1 2.4 2 0 0 2 2 2 0 HSA Scm3 PF10384.4 EIE87215.1 - 0.76 9.3 4.7 3.2 7.2 0.3 2.9 2 1 0 2 2 2 0 Centromere protein Scm3 DUF413 PF04219.7 EIE87216.1 - 0.03 14.0 0.2 0.039 13.6 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function, DUF Ran-binding PF05508.6 EIE87216.1 - 0.071 11.9 0.4 0.081 11.8 0.3 1.0 1 0 0 1 1 1 0 RanGTP-binding protein Ada3 PF10198.4 EIE87216.1 - 0.11 12.2 0.3 0.16 11.7 0.2 1.5 1 1 0 1 1 1 0 Histone acetyltransferases subunit 3 Pkinase PF00069.20 EIE87218.1 - 5.4e-66 222.3 0.0 1.1e-65 221.3 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE87218.1 - 2.8e-34 118.3 0.0 4.8e-34 117.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.17 EIE87218.1 - 1.4e-11 43.9 27.5 3.8e-06 26.5 6.3 2.7 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 EIE87218.1 - 1.3e-10 41.6 0.2 3e-10 40.4 0.1 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain HR1 PF02185.11 EIE87218.1 - 2.4e-08 33.5 22.0 0.00019 21.0 3.0 3.2 3 0 0 3 3 3 2 Hr1 repeat C2 PF00168.25 EIE87218.1 - 0.031 14.1 0.0 0.071 12.9 0.0 1.6 1 0 0 1 1 1 0 C2 domain Homeobox PF00046.24 EIE87219.1 - 6.8e-19 67.2 1.6 1.7e-18 66.0 1.1 1.7 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EIE87219.1 - 0.045 13.4 0.2 0.16 11.6 0.1 2.0 1 0 0 1 1 1 0 Homeobox KN domain TAFII55_N PF04658.8 EIE87221.1 - 0.047 13.1 0.3 0.058 12.8 0.2 1.2 1 0 0 1 1 1 0 TAFII55 protein conserved region Unstab_antitox PF09720.5 EIE87221.1 - 0.12 12.0 0.3 1.5 8.5 0.1 2.4 2 0 0 2 2 2 0 Putative addiction module component TIM21 PF08294.6 EIE87223.1 - 3.5e-16 59.1 0.0 4.1e-16 58.9 0.0 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.5 EIE87223.1 - 0.092 12.2 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Cytochrome oxidase complex assembly protein 1 Septin PF00735.13 EIE87224.1 - 1.8e-121 404.4 0.7 1.8e-121 404.4 0.5 1.7 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 EIE87224.1 - 7.6e-08 32.3 0.0 1.6e-07 31.2 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EIE87224.1 - 5.9e-06 25.5 0.0 1.5e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 EIE87224.1 - 2.9e-05 24.3 0.5 0.0016 18.7 0.0 2.5 2 0 0 2 2 2 1 ABC transporter GTP_EFTU PF00009.22 EIE87224.1 - 3.1e-05 23.4 2.0 0.0012 18.3 0.0 2.9 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain AIG1 PF04548.11 EIE87224.1 - 0.00046 19.3 0.0 0.00046 19.3 0.0 2.0 2 0 0 2 2 2 1 AIG1 family AAA_22 PF13401.1 EIE87224.1 - 0.00076 19.6 0.0 0.0043 17.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain Gtr1_RagA PF04670.7 EIE87224.1 - 0.00093 18.3 0.0 0.0028 16.8 0.0 1.8 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 EIE87224.1 - 0.0011 18.3 1.1 0.0031 16.9 0.0 2.2 2 0 0 2 2 2 1 Ras family Miro PF08477.8 EIE87224.1 - 0.0035 17.8 1.8 0.0092 16.4 0.0 2.5 3 0 0 3 3 3 1 Miro-like protein AAA_10 PF12846.2 EIE87224.1 - 0.0078 15.6 0.1 0.025 14.0 0.0 1.9 2 0 0 2 2 2 1 AAA-like domain Dynamin_N PF00350.18 EIE87224.1 - 0.017 14.9 8.0 0.31 10.8 0.1 3.3 2 2 1 3 3 3 0 Dynamin family Exonuc_VII_L PF02601.10 EIE87224.1 - 0.032 13.4 5.8 0.084 12.0 3.9 1.8 2 0 0 2 2 2 0 Exonuclease VII, large subunit AAA_16 PF13191.1 EIE87224.1 - 0.033 14.1 0.3 0.13 12.2 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain PduV-EutP PF10662.4 EIE87224.1 - 0.049 13.1 0.1 0.78 9.2 0.0 2.8 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.1 EIE87224.1 - 0.066 12.7 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.12 EIE87224.1 - 0.83 9.1 4.4 15 5.0 0.0 3.3 2 1 0 3 3 3 0 Conserved hypothetical ATP binding protein DUF2937 PF11157.3 EIE87224.1 - 1.5 8.1 4.4 2.6 7.3 3.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) IncA PF04156.9 EIE87224.1 - 2.2 7.8 7.4 4.1 6.9 5.1 1.5 1 0 0 1 1 1 0 IncA protein Atg14 PF10186.4 EIE87224.1 - 2.9 6.7 7.7 4.7 6.0 5.3 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TFIIB PF00382.14 EIE87227.1 - 1e-24 86.1 0.1 5.7e-20 70.8 0.0 2.6 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 EIE87227.1 - 3.2e-21 75.3 4.4 3.2e-21 75.3 3.0 3.3 3 1 1 4 4 4 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.7 EIE87227.1 - 1.2e-09 37.3 2.1 3.5e-09 35.8 1.4 1.9 1 0 0 1 1 1 1 TFIIB zinc-binding RRN7 PF11781.3 EIE87227.1 - 0.018 14.5 0.8 0.018 14.5 0.5 2.0 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 Ribosomal_S27e PF01667.12 EIE87227.1 - 0.037 13.5 0.4 0.086 12.3 0.3 1.6 1 0 0 1 1 1 0 Ribosomal protein S27 OrfB_Zn_ribbon PF07282.6 EIE87227.1 - 0.082 12.5 1.0 0.2 11.3 0.7 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-ribbon_3 PF13248.1 EIE87227.1 - 1.5 8.1 5.7 18 4.6 0.1 2.4 1 1 1 2 2 2 0 zinc-ribbon domain F_bP_aldolase PF01116.15 EIE87228.1 - 3e-99 331.7 0.0 3.4e-99 331.5 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II CPSase_L_D2 PF02786.12 EIE87228.1 - 0.11 11.7 0.6 1 8.6 0.1 2.1 1 1 1 2 2 2 0 Carbamoyl-phosphate synthase L chain, ATP binding domain Peptidase_C26 PF07722.8 EIE87228.1 - 0.13 11.6 0.1 0.63 9.4 0.0 2.0 2 0 0 2 2 2 0 Peptidase C26 Adaptin_N PF01602.15 EIE87229.1 - 3.9e-19 68.3 0.8 7.1e-10 37.8 0.1 2.0 1 1 1 2 2 2 2 Adaptin N terminal region DASH_Dad4 PF08650.5 EIE87229.1 - 0.71 9.8 4.6 12 5.9 0.6 2.3 1 1 1 2 2 2 0 DASH complex subunit Dad4 Adaptin_N PF01602.15 EIE87230.1 - 0.00015 20.2 0.1 0.00019 19.9 0.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region ARS2 PF04959.8 EIE87230.1 - 0.0022 18.2 0.0 0.0026 17.9 0.0 1.1 1 0 0 1 1 1 1 Arsenite-resistance protein 2 rve PF00665.21 EIE87233.1 - 3.8e-13 49.5 0.0 6.3e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 EIE87233.1 - 3.7e-05 23.3 0.1 8.6e-05 22.1 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve_3 PF13683.1 EIE87233.1 - 0.00081 18.8 0.0 0.0026 17.2 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.5 EIE87234.1 - 0.00017 20.8 0.1 0.00031 20.0 0.1 1.4 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger DUF2246 PF10229.4 EIE87234.1 - 0.0023 17.2 0.1 0.0032 16.8 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2246) NtA PF03146.10 EIE87235.1 - 0.0065 16.1 0.0 0.0098 15.5 0.0 1.3 1 0 0 1 1 1 1 Agrin NtA domain Asp_protease_2 PF13650.1 EIE87236.1 - 2.8e-08 34.1 0.0 7.6e-08 32.7 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EIE87236.1 - 5.4e-08 32.5 0.0 1.8e-07 30.8 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.5 EIE87236.1 - 0.00016 21.2 0.0 0.00029 20.3 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Viral_NABP PF05515.6 EIE87236.1 - 0.0065 16.7 5.2 0.012 15.8 3.6 1.6 1 1 0 1 1 1 1 Viral nucleic acid binding Retrotrans_gag PF03732.12 EIE87236.1 - 0.04 13.9 0.0 0.076 13.0 0.0 1.4 1 0 0 1 1 1 0 Retrotransposon gag protein DDE_3 PF13358.1 EIE87237.1 - 5.4e-19 68.3 0.3 3.1e-18 65.9 0.0 2.3 3 0 0 3 3 3 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE87237.1 - 1.1e-11 44.6 0.9 2.5e-11 43.4 0.7 1.7 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.1 EIE87237.1 - 0.0048 17.6 0.2 0.51 11.1 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_29 PF13551.1 EIE87237.1 - 0.0067 16.5 0.0 0.018 15.1 0.0 1.8 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EIE87237.1 - 0.018 14.7 0.1 0.098 12.3 0.0 2.4 3 0 0 3 3 3 0 Homeodomain-like domain Transposase_21 PF02992.9 EIE87238.1 - 1.8e-16 59.9 0.1 3.4e-16 59.0 0.0 1.5 2 0 0 2 2 2 1 Transposase family tnp2 3HCDH_N PF02737.13 EIE87238.1 - 0.057 13.0 0.0 0.098 12.3 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF4218 PF13960.1 EIE87238.1 - 0.13 11.6 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) HTH_Tnp_4 PF13613.1 EIE87239.1 - 0.0037 16.7 0.0 0.0042 16.5 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease HTH_23 PF13384.1 EIE87239.1 - 0.0085 15.7 0.0 0.009 15.6 0.0 1.1 1 0 0 1 1 1 1 Homeodomain-like domain HTH_30 PF13556.1 EIE87239.1 - 0.03 13.8 0.0 0.037 13.6 0.0 1.1 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain HTH_36 PF13730.1 EIE87239.1 - 0.091 12.9 0.0 0.096 12.8 0.0 1.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_28 PF13518.1 EIE87239.1 - 0.11 12.5 0.0 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_11 PF08279.7 EIE87239.1 - 0.11 12.1 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 HTH domain HTH_38 PF13936.1 EIE87239.1 - 0.12 11.8 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 Helix-turn-helix domain DUF2805 PF10985.3 EIE87239.1 - 0.13 12.1 0.0 0.14 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2805) HTH_Tnp_ISL3 PF13542.1 EIE87239.1 - 0.14 11.3 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Peptidase_A21 PF03566.8 EIE87240.1 - 0.099 10.7 0.0 0.13 10.2 0.0 1.1 1 0 0 1 1 1 0 Peptidase family A21 RVT_1 PF00078.22 EIE87241.1 - 5.1e-28 97.8 0.0 8.4e-28 97.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EIE87241.1 - 1.5e-18 66.4 0.0 3.9e-18 65.1 0.0 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EIE87241.1 - 1.3e-06 28.5 0.0 5.1e-06 26.6 0.0 2.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DDE_Tnp_IS1595 PF12762.2 EIE87242.1 - 8.6e-23 80.8 0.6 1.7e-22 79.9 0.3 1.6 2 0 0 2 2 2 1 ISXO2-like transposase domain Mod_r PF07200.8 EIE87243.1 - 0.0036 17.2 0.1 0.0069 16.3 0.1 1.4 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Matrilin_ccoil PF10393.4 EIE87243.1 - 0.021 14.1 0.9 0.043 13.1 0.2 1.8 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin Reo_sigmaC PF04582.7 EIE87243.1 - 0.05 12.7 0.4 0.077 12.1 0.3 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DivIC PF04977.10 EIE87243.1 - 0.11 11.9 1.5 0.23 10.9 1.0 1.5 1 0 0 1 1 1 0 Septum formation initiator DUF904 PF06005.7 EIE87243.1 - 0.65 10.3 4.1 1.1 9.5 2.3 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF904) DUF4164 PF13747.1 EIE87243.1 - 1.6 8.8 10.2 0.79 9.8 1.7 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) DUF1759 PF03564.10 EIE87244.1 - 2.2e-05 24.3 0.2 2.8e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) Retrotrans_gag PF03732.12 EIE87244.1 - 0.0008 19.4 0.1 0.0013 18.7 0.0 1.4 1 1 0 1 1 1 1 Retrotransposon gag protein Ponericin PF07442.6 EIE87244.1 - 0.17 11.7 0.7 0.31 10.8 0.5 1.5 1 0 0 1 1 1 0 Ponericin PapC_C PF13953.1 EIE87246.1 - 0.09 12.4 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 PapC C-terminal domain zf-RVT PF13966.1 EIE87250.1 - 5.4e-09 36.2 0.7 5.4e-09 36.2 0.5 2.0 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase HTH_Tnp_Tc3_2 PF01498.13 EIE87251.1 - 2.2e-09 37.2 0.8 4.2e-09 36.3 0.5 1.4 1 0 0 1 1 1 1 Transposase rve PF00665.21 EIE87254.1 - 4.6e-24 84.8 0.0 2e-23 82.7 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 EIE87254.1 - 9.3e-14 51.2 0.1 3.1e-13 49.5 0.0 1.9 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.12 EIE87254.1 - 1.8e-06 27.9 4.2 2e-06 27.7 0.1 3.0 2 0 0 2 2 2 1 Retrotransposon gag protein rve_3 PF13683.1 EIE87254.1 - 0.0052 16.2 0.1 0.022 14.2 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain SR-25 PF10500.4 EIE87254.1 - 2.6 7.4 18.0 6.8 6.1 12.5 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Muted PF14942.1 EIE87254.1 - 7 6.5 9.8 3.7 7.4 0.8 3.3 3 0 0 3 3 3 0 Organelle biogenesis, Muted-like protein DDE_3 PF13358.1 EIE87255.1 - 5.2e-18 65.2 0.0 9.5e-18 64.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE87255.1 - 3.3e-07 30.2 1.7 4.8e-07 29.7 0.5 1.8 2 0 0 2 2 2 1 Transposase HTH_Tnp_4 PF13613.1 EIE87255.1 - 0.00061 19.2 0.0 0.0012 18.3 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease HTH_23 PF13384.1 EIE87255.1 - 0.0043 16.6 0.0 0.01 15.4 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain FAM70 PF14967.1 EIE87255.1 - 0.03 13.5 0.0 0.045 12.9 0.0 1.2 1 0 0 1 1 1 0 FAM70 protein HTH_30 PF13556.1 EIE87255.1 - 0.13 11.8 0.0 0.63 9.6 0.0 2.0 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain RVT_1 PF00078.22 EIE87256.1 - 1e-26 93.6 0.0 1.7e-26 92.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EIE87256.1 - 1.8e-14 53.3 0.0 4.8e-14 51.9 0.0 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EIE87256.1 - 7.6e-06 26.0 0.0 2.4e-05 24.4 0.0 1.9 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SYCE1 PF15233.1 EIE87256.1 - 0.0078 16.1 0.5 0.018 14.9 0.3 1.5 1 0 0 1 1 1 1 Synaptonemal complex central element protein 1 TBPIP PF07106.8 EIE87256.1 - 0.37 10.3 0.1 0.69 9.4 0.0 1.3 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF972 PF06156.8 EIE87256.1 - 0.41 10.9 0.1 0.82 10.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Serglycin PF04360.7 EIE87256.1 - 6.6 6.4 10.8 0.63 9.7 2.7 2.4 2 0 0 2 2 2 0 Serglycin Transposase_21 PF02992.9 EIE87258.1 - 6.4e-22 77.7 0.0 1.5e-21 76.5 0.0 1.6 1 0 0 1 1 1 1 Transposase family tnp2 DUF1258 PF06869.7 EIE87258.1 - 0.0026 16.9 0.0 0.0041 16.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) rve PF00665.21 EIE87259.1 - 1.8e-22 79.6 0.0 4e-22 78.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE87259.1 - 1.9e-15 56.8 0.1 3.9e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.12 EIE87259.1 - 7.5e-09 35.5 0.1 2e-08 34.1 0.1 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein Chromo PF00385.19 EIE87259.1 - 7.7e-08 31.8 0.2 1.8e-07 30.6 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 EIE87259.1 - 0.00083 18.7 1.6 0.0029 16.9 1.1 2.0 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger UBN2 PF14223.1 EIE87259.1 - 0.12 12.1 0.0 0.32 10.8 0.0 1.7 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type FYDLN_acid PF09538.5 EIE87262.1 - 0.016 15.7 0.2 0.021 15.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Chromo PF00385.19 EIE87265.1 - 6.4e-14 51.3 2.2 6.4e-14 51.3 1.5 2.0 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.21 EIE87265.1 - 9.8e-14 51.4 0.0 1.8e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Med15 PF09606.5 EIE87266.1 - 0.014 13.6 12.0 0.018 13.2 8.3 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TFIIA PF03153.8 EIE87266.1 - 0.1 12.4 5.8 0.12 12.2 4.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RVT_1 PF00078.22 EIE87268.1 - 1.3e-20 73.7 0.0 2.5e-20 72.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EIE87268.1 - 1.8e-12 46.9 0.0 4.5e-12 45.6 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase ICL PF00463.16 EIE87271.1 - 6.3e-18 64.2 0.0 6.8e-18 64.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family Ras PF00071.17 EIE87272.1 - 1.3e-37 128.6 0.0 1.7e-37 128.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIE87272.1 - 3.6e-11 43.5 0.0 9.2e-11 42.2 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EIE87272.1 - 0.006 15.8 0.0 0.0084 15.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Cnd1 PF12717.2 EIE87273.1 - 0.043 13.6 0.3 0.17 11.7 0.1 2.0 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 SATase_N PF06426.9 EIE87273.1 - 0.046 13.9 3.1 0.12 12.6 2.1 1.7 1 0 0 1 1 1 0 Serine acetyltransferase, N-terminal TFIID_20kDa PF03847.8 EIE87273.1 - 0.15 12.3 4.1 0.29 11.4 0.2 2.6 1 1 1 2 2 2 0 Transcription initiation factor TFIID subunit A Baculo_PEP_C PF04513.7 EIE87273.1 - 0.86 9.4 5.2 3.4 7.4 0.3 2.8 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Herpes_UL92 PF03048.9 EIE87273.1 - 0.89 9.1 3.8 1.3 8.5 1.6 1.9 2 0 0 2 2 2 0 UL92 family NSP2-B_epitope PF14757.1 EIE87273.1 - 3.5 7.0 9.3 4.7 6.6 2.6 2.3 1 1 1 2 2 2 0 Immunogenic region of nsp2 protein of arterivirus polyprotein ApoO PF09769.4 EIE87273.1 - 8.8 6.0 9.2 1.4 8.5 3.5 1.8 2 1 0 2 2 2 0 Apolipoprotein O SNF2_N PF00176.18 EIE87275.1 - 2.3e-71 240.0 1.3 5.4e-71 238.8 0.9 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.1 EIE87275.1 - 6e-43 146.2 17.1 6e-43 146.2 11.8 3.2 4 0 0 4 4 4 1 DNA-binding domain Helicase_C PF00271.26 EIE87275.1 - 2.4e-13 49.7 0.0 6e-13 48.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S-AdoMet_synt_C PF02773.11 EIE87276.1 - 7e-77 255.8 0.1 1.2e-76 254.9 0.1 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 EIE87276.1 - 2e-47 160.0 0.0 4.6e-47 158.9 0.0 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 EIE87276.1 - 9.4e-38 128.4 0.4 2.1e-37 127.3 0.3 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain Enolase_C PF00113.17 EIE87278.1 - 2.6e-160 532.2 0.1 3.5e-160 531.7 0.1 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 EIE87278.1 - 2.8e-59 198.7 0.2 4.5e-59 198.1 0.1 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.1 EIE87278.1 - 0.0052 16.7 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.6 EIE87278.1 - 0.12 11.3 0.1 0.29 10.0 0.1 1.6 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus GCR1_C PF12550.3 EIE87279.1 - 5.1e-26 90.3 0.7 5.1e-25 87.1 0.2 2.6 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes Fungal_trans PF04082.13 EIE87280.1 - 2.5e-13 49.5 0.2 6.8e-13 48.0 0.1 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Kelch_4 PF13418.1 EIE87281.1 - 3.4e-38 129.1 1.9 4.5e-10 39.1 0.0 5.7 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_3 PF13415.1 EIE87281.1 - 7.6e-34 115.1 13.1 4.8e-08 32.9 0.0 7.0 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_6 PF13964.1 EIE87281.1 - 2.6e-33 112.8 1.7 4.8e-06 26.5 0.0 5.5 3 1 2 5 5 5 5 Kelch motif Kelch_5 PF13854.1 EIE87281.1 - 4.5e-33 112.6 4.2 2.3e-07 30.6 0.1 5.3 5 0 0 5 5 5 5 Kelch motif Kelch_1 PF01344.20 EIE87281.1 - 6.9e-29 99.1 0.2 1.1e-05 24.8 0.0 5.4 5 0 0 5 5 5 5 Kelch motif Kelch_2 PF07646.10 EIE87281.1 - 4.5e-28 95.9 4.3 5.4e-05 22.7 0.0 5.4 5 0 0 5 5 5 5 Kelch motif PQQ_3 PF13570.1 EIE87281.1 - 0.0016 18.6 6.2 2.6 8.4 0.0 5.3 5 1 0 5 5 5 1 PQQ-like domain TLD PF07534.11 EIE87282.1 - 6.2e-25 87.8 0.2 9e-25 87.2 0.1 1.2 1 0 0 1 1 1 1 TLD SSB PF00436.20 EIE87283.1 - 1.3e-23 82.8 0.1 1.6e-23 82.5 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family tRNA_anti-codon PF01336.20 EIE87283.1 - 0.04 13.7 0.1 0.084 12.7 0.0 1.6 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain DUF1971 PF09313.6 EIE87283.1 - 0.1 12.2 0.0 4.3 7.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1971) dNK PF01712.14 EIE87284.1 - 0.095 12.6 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Deoxynucleoside kinase Ribosomal_S7 PF00177.16 EIE87288.1 - 1.4e-39 134.9 0.3 1.7e-39 134.7 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Ribosomal_S21e PF01249.13 EIE87289.1 - 1.9e-38 130.2 0.0 2.1e-38 130.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e DDE_1 PF03184.14 EIE87290.1 - 3.7e-49 166.7 0.2 7.8e-49 165.7 0.1 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EIE87290.1 - 1.9e-05 24.3 0.0 5.2e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.1 EIE87290.1 - 8.8e-05 22.2 0.0 0.0002 21.1 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EIE87291.1 - 4.3e-29 101.1 0.0 3.2e-28 98.2 0.0 2.2 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_29 PF13551.1 EIE87291.1 - 3e-05 24.1 0.2 0.0012 19.0 0.0 2.6 1 1 1 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.1 EIE87291.1 - 0.0025 17.4 0.0 0.0062 16.1 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain DDE_1 PF03184.14 EIE87291.1 - 0.011 14.8 0.1 0.024 13.7 0.0 1.6 2 0 0 2 2 2 0 DDE superfamily endonuclease HTH_32 PF13565.1 EIE87291.1 - 0.025 15.3 1.5 8.8 7.2 0.1 3.1 3 1 1 4 4 4 0 Homeodomain-like domain rve PF00665.21 EIE87291.1 - 0.074 13.1 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain FliT PF05400.8 EIE87291.1 - 0.14 12.5 0.2 0.14 12.5 0.2 2.8 4 0 0 4 4 4 0 Flagellar protein FliT HTH_Tnp_Tc3_2 PF01498.13 EIE87293.1 - 3.2e-08 33.4 0.2 3.2e-08 33.4 0.1 2.1 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 EIE87293.1 - 0.00053 20.1 1.6 0.0013 18.8 1.1 1.7 1 1 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_ISL3 PF13542.1 EIE87293.1 - 0.0069 15.5 2.0 0.023 13.8 0.5 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_21 PF13276.1 EIE87293.1 - 0.062 13.3 1.6 0.61 10.1 0.0 2.3 2 0 0 2 2 2 0 HTH-like domain HTH_12 PF08461.5 EIE87293.1 - 0.066 12.9 0.1 0.19 11.4 0.1 1.7 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain HTH_23 PF13384.1 EIE87293.1 - 0.12 12.0 2.9 1.7 8.3 0.2 2.5 2 0 0 2 2 2 0 Homeodomain-like domain HTH_32 PF13565.1 EIE87293.1 - 0.35 11.6 2.5 0.38 11.5 0.6 1.9 2 0 0 2 2 2 0 Homeodomain-like domain DDE_Tnp_IS1595 PF12762.2 EIE87294.1 - 9.9e-22 77.4 1.0 1.8e-21 76.5 0.7 1.4 1 0 0 1 1 1 1 ISXO2-like transposase domain DDE_Tnp_IS1595 PF12762.2 EIE87295.1 - 4.5e-07 29.8 0.1 1.1e-06 28.5 0.1 1.6 1 0 0 1 1 1 1 ISXO2-like transposase domain DDE_3 PF13358.1 EIE87296.1 - 0.00092 18.9 0.1 0.0026 17.4 0.1 1.9 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE87296.1 - 0.016 15.2 0.1 0.29 11.2 0.0 2.8 2 0 0 2 2 2 0 Transposase Vsr PF03852.10 EIE87296.1 - 0.044 13.4 0.0 0.14 11.7 0.0 1.9 1 0 0 1 1 1 0 DNA mismatch endonuclease Vsr Lzipper-MIP1 PF14389.1 EIE87297.1 - 0.015 15.3 2.7 0.035 14.2 1.5 1.8 1 1 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 SRR PF07709.6 EIE87297.1 - 0.11 12.7 4.4 4.2 7.9 0.0 3.7 3 0 0 3 3 3 0 Seven Residue Repeat DUF4404 PF14357.1 EIE87297.1 - 0.12 12.8 1.1 3 8.3 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) IncA PF04156.9 EIE87297.1 - 1.7 8.2 5.2 3.7 7.1 3.6 1.6 1 1 0 1 1 1 0 IncA protein ChaB PF06150.7 EIE87297.1 - 3.1 7.6 6.6 0.25 11.1 0.4 2.3 2 1 1 3 3 3 0 ChaB SYCE1 PF15233.1 EIE87297.1 - 8.2 6.3 9.8 0.49 10.3 2.3 2.0 2 1 0 2 2 2 0 Synaptonemal complex central element protein 1 Transposase_21 PF02992.9 EIE87298.1 - 2.9e-23 82.1 0.1 2.9e-23 82.1 0.1 1.6 2 0 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.1 EIE87298.1 - 4.7e-05 22.8 0.3 0.00011 21.6 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) RRF_GI PF12614.3 EIE87299.1 - 0.021 14.6 0.1 0.021 14.6 0.1 1.1 1 0 0 1 1 1 0 Ribosome recycling factor FKBP_N PF01346.13 EIE87300.1 - 0.012 15.7 2.2 0.012 15.7 1.5 2.2 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase LAG1-DNAbind PF09271.6 EIE87300.1 - 0.03 14.7 0.3 0.066 13.6 0.2 1.5 1 0 0 1 1 1 0 LAG1, DNA binding YebO PF13974.1 EIE87300.1 - 0.096 12.4 8.3 0.93 9.3 0.0 2.4 2 0 0 2 2 2 0 YebO-like protein HTH_37 PF13744.1 EIE87300.1 - 2 8.2 7.2 22 4.9 3.7 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain DDE_3 PF13358.1 EIE87302.1 - 1.5e-09 37.7 2.0 2e-09 37.3 0.6 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease rve PF00665.21 EIE87303.1 - 1.1e-16 60.9 0.0 4.8e-16 58.9 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE87303.1 - 9.8e-11 41.4 0.6 7e-10 38.6 0.3 2.6 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE87303.1 - 2.7e-08 33.3 2.9 9.9e-08 31.5 0.1 2.9 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain RVP PF00077.15 EIE87303.1 - 0.0018 18.1 0.1 0.0088 15.9 0.1 2.3 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 EIE87303.1 - 0.0041 17.5 0.1 0.0092 16.4 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.12 EIE87303.1 - 0.023 14.7 0.6 0.2 11.7 0.0 3.0 3 0 0 3 3 3 0 Retrotransposon gag protein ADH_N PF08240.7 EIE87305.1 - 2.2e-24 85.3 6.2 4.4e-24 84.3 4.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIE87305.1 - 5.2e-18 64.8 0.1 8.5e-18 64.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EIE87305.1 - 1.2e-05 24.5 0.0 1.8e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EIE87305.1 - 0.0041 16.6 0.0 0.0068 15.9 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Oxidored_nitro PF00148.14 EIE87305.1 - 0.011 14.4 0.0 0.018 13.6 0.0 1.3 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase ADH_zinc_N_2 PF13602.1 EIE87305.1 - 0.015 16.1 0.0 0.026 15.4 0.0 1.5 1 1 0 1 1 1 0 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.16 EIE87305.1 - 0.04 13.4 0.0 0.057 12.9 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Methyltransf_11 PF08241.7 EIE87305.1 - 0.046 14.1 0.1 0.13 12.7 0.1 1.7 1 0 0 1 1 1 0 Methyltransferase domain ETF PF01012.16 EIE87305.1 - 0.068 12.8 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Electron transfer flavoprotein domain FHA PF00498.21 EIE87307.1 - 2.4e-06 27.5 0.1 5.9e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 FHA domain Cupin_8 PF13621.1 EIE87308.1 - 1.4e-25 90.2 0.1 2.1e-25 89.6 0.1 1.2 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 EIE87308.1 - 1.4e-17 63.9 0.3 3.3e-17 62.7 0.0 1.8 2 0 0 2 2 2 1 JmjC domain, hydroxylase hNIFK_binding PF12196.3 EIE87308.1 - 0.042 13.2 0.1 0.074 12.4 0.0 1.4 1 0 0 1 1 1 0 FHA Ki67 binding domain of hNIFK Hist_deacetyl PF00850.14 EIE87309.1 - 1.2e-60 205.4 0.1 1.1e-47 162.9 0.1 2.1 1 1 1 2 2 2 2 Histone deacetylase domain DUF2800 PF10926.3 EIE87309.1 - 0.0075 15.4 0.0 0.014 14.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2800) Brix PF04427.13 EIE87310.1 - 5.6e-54 182.6 0.8 6.4e-54 182.5 0.6 1.0 1 0 0 1 1 1 1 Brix domain DEAD PF00270.24 EIE87311.1 - 7.9e-44 149.1 0.0 1.4e-43 148.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIE87311.1 - 4.6e-26 90.4 0.0 6.3e-25 86.8 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain GUCT PF08152.7 EIE87311.1 - 8e-16 57.8 0.0 2.4e-15 56.3 0.0 1.9 1 0 0 1 1 1 1 GUCT (NUC152) domain ResIII PF04851.10 EIE87311.1 - 1.2e-06 28.5 0.0 2.9e-06 27.2 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 EIE87311.1 - 0.0044 16.1 0.0 0.0044 16.1 0.0 2.4 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.1 EIE87311.1 - 0.014 15.5 0.1 0.097 12.8 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EIE87311.1 - 0.03 14.0 0.2 0.11 12.3 0.0 2.0 2 0 0 2 2 2 0 Part of AAA domain GRP PF07172.6 EIE87311.1 - 3.6 8.1 25.9 9.9 6.7 17.9 1.7 1 0 0 1 1 1 0 Glycine rich protein family MYEOV2 PF15004.1 EIE87312.1 - 0.0017 18.8 2.0 0.0027 18.2 1.4 1.5 1 0 0 1 1 1 1 Myeloma-overexpressed-like Uso1_p115_head PF04869.9 EIE87313.1 - 5.3e-49 166.6 0.0 1.4e-42 145.5 0.0 2.6 1 1 1 2 2 2 2 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.8 EIE87313.1 - 2.1e-05 24.4 22.1 4.2e-05 23.5 15.3 1.5 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region IncA PF04156.9 EIE87313.1 - 0.00029 20.4 18.1 0.00057 19.5 12.6 1.5 1 0 0 1 1 1 1 IncA protein Arm PF00514.18 EIE87313.1 - 0.025 14.4 0.4 8.1 6.4 0.0 4.4 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat DUF2435 PF10363.4 EIE87313.1 - 0.047 13.6 5.0 24 4.9 0.1 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF2435) Ferrochelatase PF00762.14 EIE87317.1 - 0.092 11.7 0.0 0.84 8.5 0.0 2.0 1 1 1 2 2 2 0 Ferrochelatase Whi5 PF08528.6 EIE87318.1 - 2e-08 33.6 0.2 2.9e-08 33.0 0.1 1.3 1 0 0 1 1 1 1 Whi5 like Ebp2 PF05890.7 EIE87318.1 - 0.066 12.5 3.0 0.077 12.2 2.1 1.0 1 0 0 1 1 1 0 Eukaryotic rRNA processing protein EBP2 Rap_GAP PF02145.10 EIE87319.1 - 3.4e-48 163.5 0.0 1e-47 161.9 0.0 1.7 2 0 0 2 2 2 1 Rap/ran-GAP PseudoU_synth_1 PF01416.15 EIE87320.1 - 6.2e-13 49.0 0.0 4.5e-08 33.4 0.0 2.5 2 0 0 2 2 2 2 tRNA pseudouridine synthase adh_short_C2 PF13561.1 EIE87321.1 - 2.2e-17 63.6 1.1 2.5e-17 63.4 0.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EIE87321.1 - 2.2e-06 27.6 0.8 2.9e-06 27.3 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase EMP70 PF02990.11 EIE87322.1 - 2.6e-204 679.5 5.0 3.2e-204 679.2 3.5 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 CorA PF01544.13 EIE87322.1 - 6.9 5.6 9.6 19 4.1 6.7 1.7 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Pkinase PF00069.20 EIE87324.1 - 6.8e-52 176.1 0.1 1.1e-51 175.4 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE87324.1 - 2.3e-45 154.6 0.0 4.7e-45 153.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EIE87324.1 - 0.00019 20.8 0.3 0.00032 20.0 0.2 1.4 1 0 0 1 1 1 1 RIO1 family YrbL-PhoP_reg PF10707.4 EIE87324.1 - 0.0017 17.7 0.1 0.003 16.9 0.0 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kinase-like PF14531.1 EIE87324.1 - 0.0021 17.0 0.0 0.0032 16.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like NARG2_C PF10505.4 EIE87324.1 - 0.0094 15.1 0.3 0.015 14.4 0.2 1.3 1 0 0 1 1 1 1 NMDA receptor-regulated gene protein 2 C-terminus Kdo PF06293.9 EIE87324.1 - 0.026 13.6 0.0 0.045 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HABP4_PAI-RBP1 PF04774.10 EIE87326.1 - 4.7e-05 23.8 3.8 4.7e-05 23.8 2.6 3.8 2 1 1 3 3 3 1 Hyaluronan / mRNA binding family DUF2265 PF10023.4 EIE87326.1 - 0.51 9.4 9.1 0.022 13.8 2.6 1.4 2 0 0 2 2 2 0 Predicted aminopeptidase (DUF2265) TMEM237 PF15383.1 EIE87326.1 - 8.7 5.3 6.8 0.39 9.8 0.9 1.6 2 0 0 2 2 2 0 Transmembrane protein 237 PQ-loop PF04193.9 EIE87327.1 - 6.9e-21 73.5 10.5 2.9e-11 42.7 0.3 3.1 3 1 0 3 3 3 2 PQ loop repeat 4HBT PF03061.17 EIE87328.1 - 2.5e-11 43.5 0.0 3.6e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily MtrG PF04210.8 EIE87328.1 - 0.05 13.2 0.2 2.1 8.0 0.0 2.1 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G Pro_isomerase PF00160.16 EIE87329.1 - 1.8e-48 164.7 0.2 2.1e-48 164.4 0.2 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD IncA PF04156.9 EIE87331.1 - 1.8 8.1 4.7 2 7.9 3.3 1.1 1 0 0 1 1 1 0 IncA protein Atg14 PF10186.4 EIE87331.1 - 2.9 6.7 7.3 3.1 6.6 5.1 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Pil1 PF13805.1 EIE87332.1 - 1.2e-19 70.4 0.8 1.2e-19 70.4 0.6 1.6 2 0 0 2 2 2 1 Eisosome component PIL1 Atg14 PF10186.4 EIE87332.1 - 0.47 9.3 4.4 0.9 8.4 3.0 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TMPIT PF07851.8 EIE87332.1 - 0.61 9.0 1.8 0.9 8.5 1.3 1.1 1 0 0 1 1 1 0 TMPIT-like protein IncA PF04156.9 EIE87332.1 - 1.2 8.6 3.2 2.3 7.7 2.2 1.4 1 0 0 1 1 1 0 IncA protein Sec34 PF04136.10 EIE87334.1 - 5e-27 94.5 0.1 8.2e-27 93.8 0.1 1.3 1 0 0 1 1 1 1 Sec34-like family CorA PF01544.13 EIE87334.1 - 0.0022 17.0 0.1 0.007 15.4 0.0 1.6 1 1 1 2 2 2 1 CorA-like Mg2+ transporter protein Mad3_BUB1_I PF08311.7 EIE87334.1 - 0.65 9.7 3.0 1.9 8.2 0.4 2.3 1 1 2 3 3 3 0 Mad3/BUB1 homology region 1 DUF21 PF01595.15 EIE87335.1 - 5.2e-24 84.5 1.7 8.7e-24 83.8 1.1 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF21 Sulfatase PF00884.18 EIE87336.1 - 2.2e-43 148.6 2.8 2.9e-43 148.2 1.9 1.2 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.12 EIE87336.1 - 0.0017 16.8 0.0 0.0028 16.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF3820 PF12843.2 EIE87336.1 - 0.008 15.7 0.1 0.015 14.8 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3820) Phosphodiest PF01663.17 EIE87336.1 - 0.016 14.5 3.4 0.026 13.8 2.2 1.5 1 1 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 EIE87336.1 - 0.055 12.8 0.0 0.18 11.1 0.0 1.8 1 1 0 1 1 1 0 Metalloenzyme superfamily Myb_DNA-binding PF00249.26 EIE87337.1 - 3.5e-07 30.1 0.7 7.4e-07 29.1 0.5 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF1444 PF07285.6 EIE87337.1 - 0.016 14.5 0.1 0.04 13.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1444) Myb_DNA-bind_6 PF13921.1 EIE87337.1 - 0.055 13.5 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EIE87337.1 - 0.8 9.8 3.3 0.51 10.4 0.4 2.0 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain HMG_box PF00505.14 EIE87338.1 - 1.3e-24 86.2 5.1 1.3e-24 86.2 3.5 2.0 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EIE87338.1 - 5e-13 49.2 4.4 5e-13 49.2 3.0 2.0 2 0 0 2 2 2 1 HMG-box domain HMG_box_5 PF14887.1 EIE87338.1 - 0.0012 18.5 3.1 0.0012 18.5 2.2 1.9 1 1 1 2 2 2 1 HMG (high mobility group) box 5 DUF4604 PF15377.1 EIE87338.1 - 6.9 6.8 28.1 23 5.1 19.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4604) Cyclin PF08613.6 EIE87339.1 - 1.9e-10 41.3 0.1 2.2e-10 41.1 0.1 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EIE87339.1 - 6.4e-09 35.4 0.1 8.1e-09 35.1 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Ribonuc_red_sm PF00268.16 EIE87340.1 - 5.2e-119 396.4 3.9 6.3e-119 396.1 2.7 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain DUF1227 PF06777.6 EIE87341.1 - 3.2e-60 202.0 0.3 5.8e-60 201.2 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 EIE87341.1 - 1.2e-51 174.5 0.0 1.9e-51 173.9 0.0 1.3 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.1 EIE87341.1 - 4.2e-40 137.4 0.0 1.4e-39 135.7 0.0 1.8 2 0 0 2 2 2 1 Helicase C-terminal domain SNF2_N PF00176.18 EIE87341.1 - 0.0044 15.8 0.0 1.4 7.6 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain PhoH PF02562.11 EIE87341.1 - 0.0086 15.3 0.0 0.22 10.7 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein DEAD PF00270.24 EIE87341.1 - 0.079 12.4 0.1 7.3 6.0 0.0 2.6 3 0 0 3 3 3 0 DEAD/DEAH box helicase DUF2075 PF09848.4 EIE87341.1 - 0.2 10.5 0.0 2.5 6.9 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Epimerase PF01370.16 EIE87342.1 - 3.5e-68 229.5 0.0 4.8e-68 229.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EIE87342.1 - 1e-07 31.1 0.0 1.5e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EIE87342.1 - 0.0049 15.7 0.0 0.0086 14.9 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 EIE87342.1 - 0.0071 15.6 0.0 0.013 14.7 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Epimerase_Csub PF13950.1 EIE87342.1 - 0.022 14.6 0.0 0.044 13.7 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose 4-epimerase C-term subunit rve PF00665.21 EIE87343.1 - 1.9e-19 69.9 0.0 4.7e-19 68.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 EIE87343.1 - 2.5e-14 52.6 1.1 5.8e-14 51.5 0.7 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVT_1 PF00078.22 EIE87343.1 - 2.1e-12 46.8 0.2 6.5e-12 45.2 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 EIE87343.1 - 0.022 15.0 0.0 0.11 12.7 0.0 2.2 2 0 0 2 2 2 0 RNase H Asp_protease_2 PF13650.1 EIE87344.1 - 0.00019 21.8 0.0 0.00039 20.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 EIE87344.1 - 0.00024 20.9 0.2 0.00062 19.6 0.1 1.8 2 0 0 2 2 2 1 Retroviral aspartyl protease Retrotrans_gag PF03732.12 EIE87344.1 - 0.0034 17.4 0.2 0.014 15.4 0.0 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein F_actin_bind PF08919.5 EIE87344.1 - 0.023 14.4 0.2 0.15 11.7 0.0 2.5 3 0 0 3 3 3 0 F-actin binding Arteri_env PF01606.11 EIE87345.1 - 0.047 13.3 0.6 0.055 13.1 0.4 1.1 1 0 0 1 1 1 0 Arterivirus envelope protein Ribosomal_S15 PF00312.17 EIE87346.1 - 0.77 9.5 6.6 0.21 11.3 1.3 2.1 1 1 1 2 2 2 0 Ribosomal protein S15 DDE_Tnp_IS1595 PF12762.2 EIE87347.1 - 4.7e-18 65.4 0.0 7.5e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 ISXO2-like transposase domain DDE_3 PF13358.1 EIE87349.1 - 0.13 11.9 0.0 0.16 11.6 0.0 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease DDE_3 PF13358.1 EIE87351.1 - 3.4e-18 65.8 0.0 4.5e-18 65.3 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE87351.1 - 0.022 14.8 0.0 0.047 13.7 0.0 1.6 1 1 0 1 1 1 0 Integrase core domain Myb_DNA-bind_5 PF13873.1 EIE87351.1 - 0.13 12.1 0.5 14 5.6 0.2 2.5 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Transposase_21 PF02992.9 EIE87352.1 - 1.4e-21 76.6 0.1 3.7e-21 75.2 0.0 1.7 2 0 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.1 EIE87352.1 - 5.8e-07 29.0 0.5 1.4e-06 27.7 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4218) DUF3713 PF12506.3 EIE87352.1 - 0.0011 19.0 2.6 0.002 18.1 1.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3713) HTH_Tnp_Tc3_2 PF01498.13 EIE87354.1 - 2.6e-09 36.9 1.8 7e-09 35.6 0.9 2.0 1 1 1 2 2 2 1 Transposase DivIVA PF05103.8 EIE87355.1 - 0.00015 21.8 0.6 0.00019 21.4 0.4 1.1 1 0 0 1 1 1 1 DivIVA protein DivIC PF04977.10 EIE87355.1 - 0.0002 20.7 1.2 0.00026 20.3 0.9 1.1 1 0 0 1 1 1 1 Septum formation initiator bZIP_1 PF00170.16 EIE87355.1 - 0.0046 16.8 1.5 0.0069 16.3 1.0 1.2 1 0 0 1 1 1 1 bZIP transcription factor ADIP PF11559.3 EIE87355.1 - 0.0061 16.4 0.9 0.0072 16.2 0.6 1.1 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding DUF972 PF06156.8 EIE87355.1 - 0.0069 16.7 0.2 0.0085 16.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF972) MAD PF05557.8 EIE87355.1 - 0.012 13.7 0.5 0.014 13.5 0.3 1.0 1 0 0 1 1 1 0 Mitotic checkpoint protein bZIP_2 PF07716.10 EIE87355.1 - 0.02 14.6 4.0 0.021 14.6 2.2 1.5 1 1 0 1 1 1 0 Basic region leucine zipper ATG16 PF08614.6 EIE87355.1 - 0.021 14.6 0.2 0.025 14.4 0.2 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Herpes_UL6 PF01763.11 EIE87355.1 - 0.023 12.9 0.1 0.026 12.7 0.0 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like Ax_dynein_light PF10211.4 EIE87355.1 - 0.029 14.2 0.2 0.032 14.0 0.1 1.2 1 0 0 1 1 1 0 Axonemal dynein light chain BCAS2 PF05700.6 EIE87355.1 - 0.031 13.7 0.2 0.036 13.5 0.1 1.1 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) DASH_Spc34 PF08657.5 EIE87355.1 - 0.037 13.6 0.0 0.043 13.4 0.0 1.1 1 0 0 1 1 1 0 DASH complex subunit Spc34 IncA PF04156.9 EIE87355.1 - 0.054 13.0 0.2 0.064 12.8 0.1 1.1 1 0 0 1 1 1 0 IncA protein XhlA PF10779.4 EIE87355.1 - 0.056 13.3 2.3 0.075 12.9 1.6 1.2 1 0 0 1 1 1 0 Haemolysin XhlA Alpha-2-MRAP_C PF06401.6 EIE87355.1 - 0.056 13.2 0.1 0.065 13.0 0.0 1.1 1 0 0 1 1 1 0 Alpha-2-macroglobulin RAP, C-terminal domain TMF_DNA_bd PF12329.3 EIE87355.1 - 0.058 13.2 4.4 0.082 12.7 3.1 1.1 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding TACC PF05010.9 EIE87355.1 - 0.062 13.0 0.1 0.075 12.7 0.1 1.1 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) BLOC1_2 PF10046.4 EIE87355.1 - 0.072 13.2 0.8 0.099 12.7 0.6 1.1 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HAP1_N PF04849.8 EIE87355.1 - 0.074 11.9 1.0 0.089 11.7 0.7 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region Shugoshin_N PF07558.6 EIE87355.1 - 0.081 12.6 1.4 0.17 11.5 0.7 1.7 1 1 1 2 2 2 0 Shugoshin N-terminal coiled-coil region DUF4446 PF14584.1 EIE87355.1 - 0.11 12.3 0.2 0.13 12.1 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DUF4140 PF13600.1 EIE87355.1 - 0.12 12.8 0.6 0.15 12.4 0.4 1.1 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF2630 PF10944.3 EIE87355.1 - 0.15 12.1 1.8 0.24 11.5 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2630) DUF3972 PF13118.1 EIE87355.1 - 0.17 11.9 1.8 0.24 11.4 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3972) NEMO PF11577.3 EIE87355.1 - 0.18 11.5 1.7 0.27 11.0 1.1 1.2 1 0 0 1 1 1 0 NF-kappa-B essential modulator NEMO DUF904 PF06005.7 EIE87355.1 - 0.25 11.6 2.7 0.36 11.1 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF904) rve PF00665.21 EIE87356.1 - 1.1e-16 60.9 0.0 4.8e-16 58.9 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE87356.1 - 6.3e-11 42.0 0.5 5.5e-10 38.9 0.2 2.6 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE87356.1 - 2.8e-08 33.3 2.9 9.9e-08 31.5 0.1 2.9 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain RVP PF00077.15 EIE87356.1 - 0.002 17.9 0.1 0.0088 15.9 0.1 2.2 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 EIE87356.1 - 0.0042 17.5 0.1 0.0092 16.4 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.12 EIE87356.1 - 0.033 14.2 0.0 0.26 11.4 0.0 2.6 1 0 0 1 1 1 0 Retrotransposon gag protein DDE_Tnp_IS1595 PF12762.2 EIE87357.1 - 2e-07 30.9 0.1 4.6e-07 29.8 0.1 1.6 1 0 0 1 1 1 1 ISXO2-like transposase domain DDE_3 PF13358.1 EIE87358.1 - 3.6e-18 65.7 0.0 5.9e-18 65.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Ku_PK_bind PF08785.6 EIE87358.1 - 0.0021 17.9 0.0 0.0039 17.0 0.0 1.5 1 0 0 1 1 1 1 Ku C terminal domain like rve PF00665.21 EIE87358.1 - 0.013 15.5 0.0 0.018 15.1 0.0 1.3 1 0 0 1 1 1 0 Integrase core domain DUF1018 PF06252.7 EIE87358.1 - 0.075 13.5 0.1 0.22 12.0 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1018) TC1 PF15063.1 EIE87358.1 - 0.11 12.0 0.1 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Thyroid cancer protein 1 HTH_Tnp_Tc3_2 PF01498.13 EIE87359.1 - 7.5e-11 41.9 3.1 2.3e-10 40.3 0.8 2.1 2 0 0 2 2 2 1 Transposase HTH_Tnp_4 PF13613.1 EIE87359.1 - 0.011 15.2 0.0 0.029 13.9 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix of DDE superfamily endonuclease RecX PF02631.11 EIE87359.1 - 0.016 15.4 0.3 0.026 14.7 0.2 1.4 1 1 0 1 1 1 0 RecX family HTH_23 PF13384.1 EIE87359.1 - 0.07 12.7 0.0 0.22 11.2 0.0 1.8 1 0 0 1 1 1 0 Homeodomain-like domain DDE_3 PF13358.1 EIE87360.1 - 8e-18 64.5 0.2 1.1e-17 64.0 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HMG_box_2 PF09011.5 EIE87360.1 - 0.02 15.2 0.2 0.045 14.1 0.1 1.6 1 0 0 1 1 1 0 HMG-box domain rve PF00665.21 EIE87360.1 - 0.028 14.5 0.0 0.098 12.7 0.0 2.0 1 1 0 1 1 1 0 Integrase core domain Viral_DNA_bi PF02236.12 EIE87360.1 - 0.09 12.9 0.2 1.3 9.2 0.0 2.2 2 0 0 2 2 2 0 Viral DNA-binding protein, all alpha domain HMG_box PF00505.14 EIE87360.1 - 0.11 12.8 0.6 0.21 11.8 0.4 1.6 1 0 0 1 1 1 0 HMG (high mobility group) box Transposase_21 PF02992.9 EIE87361.1 - 1.3e-22 80.0 0.1 1.3e-22 80.0 0.1 1.6 2 0 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.1 EIE87361.1 - 2.2e-05 23.9 0.4 4.9e-05 22.7 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Lzipper-MIP1 PF14389.1 EIE87362.1 - 0.005 16.9 0.4 0.013 15.5 0.3 1.7 1 0 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 ChaB PF06150.7 EIE87362.1 - 0.069 12.9 0.6 0.25 11.1 0.1 2.2 2 0 0 2 2 2 0 ChaB IncA PF04156.9 EIE87362.1 - 0.17 11.4 1.2 0.28 10.7 0.9 1.4 1 0 0 1 1 1 0 IncA protein SRR PF07709.6 EIE87362.1 - 0.23 11.7 4.4 5.5 7.6 0.0 3.5 3 0 0 3 3 3 0 Seven Residue Repeat Mod_r PF07200.8 EIE87363.1 - 0.00027 20.8 0.1 0.00051 19.9 0.1 1.4 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Matrilin_ccoil PF10393.4 EIE87363.1 - 0.023 14.0 0.2 0.05 12.9 0.2 1.5 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin Reo_sigmaC PF04582.7 EIE87363.1 - 0.068 12.3 1.1 0.1 11.7 0.8 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein TMF_DNA_bd PF12329.3 EIE87363.1 - 0.14 11.9 4.0 1.5 8.6 1.4 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding RVT_1 PF00078.22 EIE87364.1 - 1.1e-28 100.1 0.0 1.7e-28 99.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EIE87364.1 - 1.6e-18 66.4 0.0 3.4e-18 65.3 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EIE87364.1 - 5.2e-05 23.3 0.0 0.00018 21.5 0.0 1.9 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HTH_Tnp_Tc3_2 PF01498.13 EIE87365.1 - 1.5e-09 37.8 3.0 4.3e-09 36.2 0.2 2.6 2 1 1 3 3 3 1 Transposase HTH_23 PF13384.1 EIE87365.1 - 9.4e-05 21.9 0.0 0.0002 20.9 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_7 PF02796.10 EIE87365.1 - 0.00097 18.9 0.2 0.0031 17.3 0.1 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase GcrA PF07750.6 EIE87365.1 - 0.044 13.9 0.1 0.05 13.8 0.0 1.3 1 1 0 1 1 1 0 GcrA cell cycle regulator DUF433 PF04255.9 EIE87365.1 - 0.13 11.6 0.0 0.29 10.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF433) Transposase_21 PF02992.9 EIE87366.1 - 2.5e-21 75.8 1.4 2.9e-21 75.6 0.0 1.7 2 0 0 2 2 2 1 Transposase family tnp2 DUF1258 PF06869.7 EIE87366.1 - 0.0037 16.3 0.3 0.0077 15.3 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1258) YebO PF13974.1 EIE87367.1 - 0.031 14.0 8.8 0.57 10.0 0.0 2.5 2 0 0 2 2 2 0 YebO-like protein LexA_DNA_bind PF01726.11 EIE87367.1 - 0.057 12.9 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 LexA DNA binding domain LAG1-DNAbind PF09271.6 EIE87367.1 - 0.13 12.7 3.1 0.14 12.6 1.3 1.7 1 1 0 1 1 1 0 LAG1, DNA binding AAA_13 PF13166.1 EIE87367.1 - 0.18 10.2 7.3 5.8 5.2 4.3 2.0 2 0 0 2 2 2 0 AAA domain DUF2508 PF10704.4 EIE87367.1 - 0.29 11.3 6.2 7.9 6.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) FKBP_N PF01346.13 EIE87367.1 - 1.7 8.6 11.4 0.35 10.9 3.7 2.5 3 0 0 3 3 3 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase SIS PF01380.17 EIE87368.1 - 0.055 13.0 0.1 0.068 12.7 0.1 1.2 1 0 0 1 1 1 0 SIS domain DDE_Tnp_IS1595 PF12762.2 EIE87369.1 - 2.1e-22 79.5 0.5 3.5e-22 78.8 0.4 1.3 1 0 0 1 1 1 1 ISXO2-like transposase domain RVT_1 PF00078.22 EIE87370.1 - 3.1e-18 65.9 0.0 5.3e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_3 PF13358.1 EIE87371.1 - 3e-13 49.7 0.0 4.9e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_23 PF13384.1 EIE87371.1 - 0.00031 20.2 0.0 0.00055 19.5 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_7 PF02796.10 EIE87371.1 - 0.0033 17.2 0.1 0.008 16.0 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase DUF2567 PF10821.3 EIE87371.1 - 0.18 11.2 0.0 0.25 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2567) Retrotrans_gag PF03732.12 EIE87372.1 - 6.2e-06 26.1 1.7 1.3e-05 25.1 0.2 2.1 2 0 0 2 2 2 1 Retrotransposon gag protein gag-asp_proteas PF13975.1 EIE87372.1 - 9.1e-06 25.4 0.3 3.2e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.18 EIE87372.1 - 8.5e-05 22.2 3.3 0.00014 21.6 2.3 1.4 1 0 0 1 1 1 1 Zinc knuckle Asp_protease_2 PF13650.1 EIE87372.1 - 0.00097 19.5 0.0 0.0039 17.6 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease DDE_3 PF13358.1 EIE87373.1 - 8.4e-09 35.3 0.1 1.1e-08 34.9 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE87374.1 - 1.1e-19 70.2 2.0 2.8e-19 68.9 0.8 1.9 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 EIE87374.1 - 7.5e-09 35.7 1.0 1.5e-08 34.7 0.7 1.4 1 1 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EIE87374.1 - 3.5e-05 23.2 2.3 0.00095 18.7 0.0 3.1 3 1 0 3 3 3 1 Homeodomain-like domain HTH_32 PF13565.1 EIE87374.1 - 0.00012 22.7 2.6 0.00039 21.1 0.2 2.5 2 1 1 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.1 EIE87374.1 - 0.0029 17.5 0.1 0.012 15.5 0.0 2.2 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_12 PF08461.5 EIE87374.1 - 0.019 14.7 1.1 0.046 13.4 0.2 2.0 1 1 1 2 2 2 0 Ribonuclease R winged-helix domain HTH_21 PF13276.1 EIE87374.1 - 0.028 14.4 0.3 0.54 10.2 0.0 2.6 2 1 1 3 3 3 0 HTH-like domain HTH_17 PF12728.2 EIE87374.1 - 0.042 14.0 0.8 0.21 11.8 0.1 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain Trp_repressor PF01371.14 EIE87374.1 - 0.052 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Trp repressor protein HTH_7 PF02796.10 EIE87374.1 - 0.056 13.3 1.6 0.22 11.4 0.1 2.5 2 1 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_40 PF14493.1 EIE87374.1 - 0.076 13.2 0.1 0.24 11.6 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_5 PF01022.15 EIE87374.1 - 0.34 10.6 1.8 2.6 7.7 0.0 2.8 3 1 0 3 3 3 0 Bacterial regulatory protein, arsR family A1_Propeptide PF07966.7 EIE87374.1 - 0.9 9.4 3.0 20 5.1 0.1 2.8 3 0 0 3 3 3 0 A1 Propeptide Leader_Erm PF08253.6 EIE87375.1 - 0.33 10.4 0.3 0.33 10.4 0.2 2.1 2 0 0 2 2 2 0 Erm Leader peptide rve PF00665.21 EIE87376.1 - 1.9e-22 79.6 0.0 4.5e-22 78.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE87376.1 - 1.4e-15 57.2 0.1 2.8e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.12 EIE87376.1 - 8.2e-09 35.4 0.1 2.3e-08 34.0 0.1 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein Chromo PF00385.19 EIE87376.1 - 4.2e-08 32.7 0.1 9.7e-08 31.5 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 EIE87376.1 - 0.00047 19.5 1.6 0.0015 17.9 1.1 1.9 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger UBN2 PF14223.1 EIE87376.1 - 0.13 12.0 0.0 0.36 10.6 0.0 1.8 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Glyco_hydro_20 PF00728.17 EIE87379.1 - 5.2e-78 262.6 5.5 1.4e-75 254.6 3.8 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 EIE87379.1 - 1.9e-23 83.5 0.0 4.1e-23 82.4 0.0 1.6 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 EIE87379.1 - 0.001 19.6 0.0 0.0021 18.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 DUF663 PF04950.7 EIE87380.1 - 2.3e-109 364.9 0.3 4.2e-109 364.0 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EIE87380.1 - 2.2e-25 87.9 0.0 6.7e-25 86.4 0.0 1.9 2 0 0 2 2 2 1 AARP2CN (NUC121) domain Nop14 PF04147.7 EIE87380.1 - 5.9 4.6 23.7 9.5 3.9 16.5 1.2 1 0 0 1 1 1 0 Nop14-like family Biopterin_H PF00351.16 EIE87381.1 - 1.3e-137 457.9 0.0 1.9e-137 457.4 0.0 1.2 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase ACT PF01842.20 EIE87381.1 - 0.00078 18.8 0.0 0.0014 18.0 0.0 1.4 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.1 EIE87381.1 - 0.0052 17.0 0.1 0.0094 16.2 0.1 1.4 1 0 0 1 1 1 1 ACT domain Sugar_tr PF00083.19 EIE87383.1 - 4.3e-87 292.5 15.2 7.3e-87 291.8 10.5 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIE87383.1 - 1.8e-28 99.2 58.0 2.4e-26 92.2 20.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EIE87383.1 - 2.3e-08 32.8 7.2 7.8e-06 24.5 1.2 3.9 2 2 2 4 4 4 2 MFS/sugar transport protein TRI12 PF06609.8 EIE87383.1 - 0.0033 15.6 3.7 0.0033 15.6 2.5 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Phage_CII PF05269.6 EIE87383.1 - 0.42 10.6 1.9 3.8 7.5 0.2 2.6 3 0 0 3 3 3 0 Bacteriophage CII protein WD40 PF00400.27 EIE87385.1 - 2.2e-07 30.4 0.0 0.0059 16.4 0.0 3.9 4 0 0 4 4 4 2 WD domain, G-beta repeat Pox_Ag35 PF03286.9 EIE87385.1 - 0.00024 20.7 4.6 0.0005 19.6 3.2 1.5 1 0 0 1 1 1 1 Pox virus Ag35 surface protein SSXRD PF09514.5 EIE87385.1 - 0.04 13.2 0.2 0.11 11.7 0.1 1.8 1 0 0 1 1 1 0 SSXRD motif Peptidase_S49_N PF08496.5 EIE87385.1 - 0.056 13.2 7.2 0.15 11.8 4.9 1.7 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Hira PF07569.6 EIE87385.1 - 0.11 11.6 1.4 8 5.6 0.0 3.2 4 0 0 4 4 4 0 TUP1-like enhancer of split DNA_pol_A_exo1 PF01612.15 EIE87386.1 - 5.3e-12 45.5 0.2 1.4e-11 44.1 0.2 1.7 1 0 0 1 1 1 1 3'-5' exonuclease RNA_pol_Rpb2_2 PF04561.9 EIE87387.1 - 1 8.7 5.8 1.5 8.1 4.0 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 2 WD40 PF00400.27 EIE87388.1 - 1.4e-12 46.9 8.3 1.3e-06 28.0 0.2 5.4 5 1 0 5 5 5 2 WD domain, G-beta repeat CLTH PF10607.4 EIE87388.1 - 0.001 18.7 1.8 0.002 17.8 1.3 1.5 1 1 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain GPI-anchored PF10342.4 EIE87389.1 - 2.9e-16 59.7 2.3 2.9e-16 59.7 1.6 2.1 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family G-patch PF01585.18 EIE87390.1 - 8.2e-16 57.5 0.1 2.3e-15 56.1 0.1 1.8 1 0 0 1 1 1 1 G-patch domain R3H PF01424.17 EIE87390.1 - 6.6e-09 35.3 0.0 2.5e-08 33.4 0.0 2.1 1 0 0 1 1 1 1 R3H domain G-patch_2 PF12656.2 EIE87390.1 - 6.6e-08 32.2 0.8 6.6e-08 32.2 0.5 3.7 3 1 0 3 3 3 1 DExH-box splicing factor binding site INTS5_N PF14837.1 EIE87390.1 - 3.5 6.9 4.5 5.9 6.2 0.9 2.4 2 0 0 2 2 2 0 Integrator complex subunit 5 N-terminus Fasciclin PF02469.17 EIE87391.1 - 2.7e-61 205.2 0.3 7.4e-17 61.5 0.0 5.2 5 0 0 5 5 5 5 Fasciclin domain p450 PF00067.17 EIE87392.1 - 1.3e-69 234.9 0.1 1.9e-69 234.4 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 HTH_32 PF13565.1 EIE87393.1 - 0.059 14.1 0.0 0.24 12.1 0.0 2.1 1 1 0 1 1 1 0 Homeodomain-like domain Aromatic_hydrox PF11723.3 EIE87394.1 - 0.038 13.2 0.1 0.055 12.7 0.1 1.2 1 0 0 1 1 1 0 Homotrimeric ring hydroxylase PWWP PF00855.12 EIE87396.1 - 3.5e-17 62.3 0.1 3.5e-17 62.3 0.1 2.8 3 1 0 3 3 3 1 PWWP domain Med26 PF08711.6 EIE87396.1 - 2.9e-06 26.6 0.0 7.3e-06 25.3 0.0 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Hid1 PF12722.2 EIE87396.1 - 0.0024 15.6 13.2 0.0027 15.4 9.1 1.1 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein CDC27 PF09507.5 EIE87396.1 - 4.1 6.5 35.0 6.2 5.9 24.2 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Chordopox_A33R PF05966.7 EIE87397.1 - 0.062 12.0 0.5 0.057 12.1 0.4 1.0 1 0 0 1 1 1 0 Chordopoxvirus A33R protein DUF4580 PF15162.1 EIE87397.1 - 0.12 11.7 0.4 0.13 11.6 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4580) bZIP_1 PF00170.16 EIE87398.1 - 2.2e-11 43.5 12.2 4.5e-11 42.5 8.5 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EIE87398.1 - 1.1e-07 31.5 11.5 2.4e-07 30.4 8.0 1.6 1 0 0 1 1 1 1 Basic region leucine zipper Glyco_trans_4_3 PF12000.3 EIE87398.1 - 0.065 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Gkycosyl transferase family 4 group HAUS6_N PF14661.1 EIE87398.1 - 1.3 8.3 6.6 0.21 10.8 2.2 1.5 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus bZIP_Maf PF03131.12 EIE87398.1 - 1.4 9.2 11.2 0.077 13.2 3.9 1.8 2 0 0 2 2 2 0 bZIP Maf transcription factor Methyltransf_2 PF00891.13 EIE87400.1 - 9.7e-07 28.2 0.0 2e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_11 PF08241.7 EIE87400.1 - 1.2e-06 28.8 0.0 2.8e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIE87400.1 - 5.1e-06 26.1 0.4 1.1e-05 25.0 0.3 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIE87400.1 - 2.8e-05 23.8 0.0 4.5e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIE87400.1 - 0.00017 22.1 0.0 0.00037 21.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIE87400.1 - 0.00031 21.1 0.1 0.0011 19.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 EIE87400.1 - 0.00041 19.4 0.2 0.0012 17.8 0.0 1.9 2 1 0 2 2 2 1 Putative methyltransferase Methyltransf_25 PF13649.1 EIE87400.1 - 0.001 19.3 0.1 0.0043 17.3 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EIE87400.1 - 0.0016 17.5 0.1 0.0074 15.3 0.0 2.0 1 1 1 2 2 2 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 EIE87400.1 - 0.038 13.3 0.0 0.065 12.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain PCMT PF01135.14 EIE87400.1 - 0.069 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) EF-hand_4 PF12763.2 EIE87400.1 - 0.084 12.6 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand HSF_DNA-bind PF00447.12 EIE87401.1 - 3.3e-35 120.3 0.7 1.1e-34 118.7 0.5 1.9 1 0 0 1 1 1 1 HSF-type DNA-binding TBPIP PF07106.8 EIE87401.1 - 0.001 18.6 3.3 0.55 9.7 1.1 2.6 2 0 0 2 2 2 2 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) NPV_P10 PF05531.7 EIE87401.1 - 0.066 13.4 0.1 0.066 13.4 0.1 3.1 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Myosin_head PF00063.16 EIE87402.1 - 1.3e-183 611.8 0.4 1.3e-183 611.8 0.3 3.0 2 1 1 3 3 3 2 Myosin head (motor domain) IQ PF00612.22 EIE87402.1 - 0.0046 16.4 0.3 0.0046 16.4 0.2 2.7 2 0 0 2 2 2 1 IQ calmodulin-binding motif Reo_sigmaC PF04582.7 EIE87402.1 - 0.52 9.4 7.4 0.93 8.6 5.1 1.4 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Pkinase PF00069.20 EIE87403.1 - 5.8e-48 163.2 0.1 4e-47 160.5 0.0 2.1 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE87403.1 - 1e-23 83.7 0.0 2.1e-23 82.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE87403.1 - 1.6e-05 24.0 0.0 2.5e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EIE87403.1 - 0.0029 16.7 0.0 0.0079 15.2 0.0 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIE87403.1 - 0.0048 16.6 0.2 0.011 15.4 0.1 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EIE87403.1 - 0.013 14.3 0.1 0.02 13.6 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase YscJ_FliF_C PF08345.6 EIE87403.1 - 0.064 13.2 1.2 0.097 12.6 0.9 1.1 1 0 0 1 1 1 0 Flagellar M-ring protein C-terminal FAT PF02259.18 EIE87404.1 - 3.9e-67 226.7 8.3 3.9e-67 226.7 5.8 2.0 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.22 EIE87404.1 - 9.4e-14 51.4 0.3 3.7e-13 49.4 0.2 2.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase GSDH PF07995.6 EIE87404.1 - 0.22 10.5 0.0 0.42 9.6 0.0 1.4 1 0 0 1 1 1 0 Glucose / Sorbosone dehydrogenase MFS_1 PF07690.11 EIE87405.1 - 0.0026 16.5 36.4 0.0066 15.1 7.6 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2759 PF10958.3 EIE87405.1 - 0.9 9.1 6.8 0.41 10.2 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2759) MFS_Mycoplasma PF07672.8 EIE87405.1 - 3.3 6.8 10.7 0.18 10.9 3.0 2.1 2 1 0 2 2 2 0 Mycoplasma MFS transporter IQ PF00612.22 EIE87406.1 - 0.00014 21.1 1.9 0.00036 19.9 1.3 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif Myosin_tail_1 PF01576.14 EIE87406.1 - 0.0017 16.2 22.4 0.18 9.4 7.5 2.3 1 1 1 2 2 2 2 Myosin tail Lzipper-MIP1 PF14389.1 EIE87406.1 - 0.0089 16.1 20.5 0.046 13.8 4.5 3.4 1 1 2 3 3 3 1 Leucine-zipper of ternary complex factor MIP1 ALIX_LYPXL_bnd PF13949.1 EIE87406.1 - 0.067 12.1 12.4 0.13 11.2 8.6 1.4 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV MscS_porin PF12795.2 EIE87406.1 - 0.12 11.6 17.8 0.1 11.8 2.9 2.5 3 0 0 3 3 3 0 Mechanosensitive ion channel porin domain LLC1 PF14945.1 EIE87406.1 - 0.75 10.1 6.7 0.27 11.5 0.2 2.7 2 0 0 2 2 2 0 Normal lung function maintenance, Low in Lung Cancer 1 protein DUF4559 PF15112.1 EIE87406.1 - 1.5 7.9 14.6 0.84 8.7 4.9 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4559) DUF572 PF04502.8 EIE87406.1 - 2.4 7.3 21.2 7.4 5.6 14.7 1.8 1 1 0 1 1 1 0 Family of unknown function (DUF572) HR1 PF02185.11 EIE87406.1 - 3.2 7.5 13.5 1.2 8.9 2.9 2.6 1 1 1 2 2 2 0 Hr1 repeat DUF4140 PF13600.1 EIE87406.1 - 4.9 7.6 16.4 0.69 10.3 0.2 3.8 3 1 1 4 4 4 0 N-terminal domain of unknown function (DUF4140) DDE_3 PF13358.1 EIE87409.1 - 3.4e-09 36.5 0.0 4.3e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Ribosomal_S3Ae PF01015.13 EIE87411.1 - 4.5e-79 264.3 7.0 5.3e-79 264.0 4.8 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Spt4 PF06093.8 EIE87411.1 - 0.11 12.3 0.3 0.94 9.4 0.0 2.3 2 0 0 2 2 2 0 Spt4/RpoE2 zinc finger DUF496 PF04363.7 EIE87411.1 - 4.1 7.2 6.4 3.8 7.4 0.4 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF496) Aminotran_3 PF00202.16 EIE87412.1 - 2.3e-109 365.3 0.0 2.7e-109 365.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 EIE87412.1 - 0.0053 15.9 0.0 0.0089 15.2 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 EIE87412.1 - 0.037 12.9 0.0 0.056 12.3 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Cecropin PF00272.14 EIE87412.1 - 0.12 11.9 0.0 17 5.0 0.0 2.5 2 0 0 2 2 2 0 Cecropin family RRM_1 PF00076.17 EIE87414.1 - 0.13 11.9 0.0 0.15 11.7 0.0 1.1 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nuc_sug_transp PF04142.10 EIE87415.1 - 5.2e-90 300.8 12.0 6.8e-90 300.4 8.3 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.15 EIE87415.1 - 9.2e-09 35.4 4.1 9.2e-09 35.4 2.8 2.6 2 1 0 2 2 2 1 EamA-like transporter family TPT PF03151.11 EIE87415.1 - 5.3e-06 26.1 24.9 0.00015 21.4 4.1 2.9 2 1 0 2 2 2 2 Triose-phosphate Transporter family EmrE PF13536.1 EIE87415.1 - 0.00011 22.3 4.6 0.00011 22.3 3.2 2.7 2 1 0 2 2 2 1 Multidrug resistance efflux transporter UAA PF08449.6 EIE87415.1 - 0.00025 20.0 21.1 0.00037 19.5 14.7 1.3 1 0 0 1 1 1 1 UAA transporter family GTP_EFTU PF00009.22 EIE87416.1 - 1.8e-61 206.9 0.0 2.5e-61 206.4 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EIE87416.1 - 4.1e-36 123.1 0.0 1e-35 121.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 EIE87416.1 - 2.2e-22 78.6 0.0 5.5e-22 77.4 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EIE87416.1 - 5.8e-14 51.9 0.9 1.8e-13 50.3 0.1 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EIE87416.1 - 2.4e-13 49.7 0.0 5.5e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 EIE87416.1 - 0.00014 21.8 0.0 0.00031 20.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AT_hook PF02178.14 EIE87417.1 - 0.041 13.5 6.7 0.094 12.4 4.6 1.6 1 0 0 1 1 1 0 AT hook motif Metallophos PF00149.23 EIE87418.1 - 5.2e-39 133.7 0.1 7.5e-39 133.2 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.7 EIE87418.1 - 1.4e-30 105.1 4.5 1.6e-30 104.9 1.6 2.2 2 0 0 2 2 2 1 PPP5 TPR repeat region TPR_11 PF13414.1 EIE87418.1 - 7.4e-17 60.7 6.5 5.1e-12 45.2 1.2 3.1 2 1 1 3 3 3 2 TPR repeat TPR_2 PF07719.12 EIE87418.1 - 3.2e-10 39.1 4.5 0.025 14.4 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 EIE87418.1 - 5e-10 38.5 12.3 0.00024 20.5 0.1 4.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 EIE87418.1 - 2.7e-06 27.1 3.1 0.0086 16.2 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 EIE87418.1 - 9.5e-05 22.4 1.0 0.0002 21.4 0.7 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EIE87418.1 - 0.00024 21.6 0.2 0.091 13.4 0.1 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 EIE87418.1 - 0.00032 20.9 0.4 0.039 14.2 0.2 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 EIE87418.1 - 0.00057 19.6 0.0 0.011 15.6 0.0 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EIE87418.1 - 0.012 15.5 1.0 0.21 11.5 0.3 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 EIE87418.1 - 0.032 13.4 0.1 6.6 6.0 0.0 3.1 3 0 0 3 3 3 0 SHNi-TPR TPR_14 PF13428.1 EIE87418.1 - 0.12 13.0 0.0 4.1 8.3 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 EIE87418.1 - 0.81 9.6 6.0 3.7 7.5 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF1640 PF07798.6 EIE87419.1 - 5.9e-22 78.5 7.3 5.9e-22 78.5 5.1 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1640) Peptidase_M56 PF05569.6 EIE87419.1 - 0.015 14.3 0.2 0.034 13.1 0.0 1.6 2 0 0 2 2 2 0 BlaR1 peptidase M56 DUF2062 PF09835.4 EIE87419.1 - 0.11 12.1 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) SNARE_assoc PF09335.6 EIE87419.1 - 0.12 12.5 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 SNARE associated Golgi protein DUF3824 PF12868.2 EIE87419.1 - 0.35 11.7 0.3 0.35 11.7 0.2 2.0 3 0 0 3 3 3 0 Domain of unknwon function (DUF3824) DUF1451 PF07295.6 EIE87419.1 - 0.84 9.4 4.8 0.6 9.8 1.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1451) WD40 PF00400.27 EIE87420.1 - 7.5e-32 108.0 11.1 2.1e-08 33.7 0.5 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 EIE87420.1 - 0.00014 20.1 1.9 0.0005 18.3 0.4 2.2 1 1 0 2 2 2 1 Nucleoporin Nup120/160 Mito_carr PF00153.22 EIE87421.1 - 5.9e-65 215.0 2.7 1.5e-23 82.2 0.0 3.2 2 1 1 3 3 3 3 Mitochondrial carrier protein Fe-S_biosyn PF01521.15 EIE87421.1 - 7.4e-15 54.8 0.3 1.4e-14 53.9 0.2 1.5 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis GATA PF00320.22 EIE87422.1 - 5.9e-10 38.3 1.0 1.3e-09 37.2 0.7 1.6 1 0 0 1 1 1 1 GATA zinc finger dsrm PF00035.20 EIE87422.1 - 0.021 15.3 4.9 0.027 15.0 1.7 2.0 2 0 0 2 2 2 0 Double-stranded RNA binding motif Snf7 PF03357.16 EIE87422.1 - 0.098 12.0 0.9 0.14 11.5 0.6 1.2 1 0 0 1 1 1 0 Snf7 Chorion_2 PF03964.10 EIE87422.1 - 0.2 12.1 3.3 0.3 11.6 2.3 1.5 1 1 0 1 1 1 0 Chorion family 2 B12D PF06522.6 EIE87423.1 - 6.3e-06 25.8 0.0 7.6e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit LtrA PF06772.6 EIE87424.1 - 3.1e-32 111.8 21.6 3.1e-32 111.8 15.0 2.1 2 0 0 2 2 2 1 Bacterial low temperature requirement A protein (LtrA) Zip PF02535.17 EIE87424.1 - 0.0046 16.0 2.1 0.0046 16.0 1.5 3.2 2 1 0 2 2 2 1 ZIP Zinc transporter DUF1041 PF06292.12 EIE87424.1 - 0.055 13.6 0.4 0.24 11.5 0.3 2.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1041) TMF_TATA_bd PF12325.3 EIE87425.1 - 1.1e-05 25.1 1.4 2.1e-05 24.2 1.0 1.5 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding CENP-F_leu_zip PF10473.4 EIE87425.1 - 0.00013 21.8 4.3 0.00028 20.7 3.0 1.5 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2296 PF10058.4 EIE87425.1 - 0.00019 21.0 0.7 0.00042 19.9 0.5 1.6 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) DivIVA PF05103.8 EIE87425.1 - 0.00021 21.3 4.1 0.00021 21.3 2.9 2.0 3 0 0 3 3 2 1 DivIVA protein Golgin_A5 PF09787.4 EIE87425.1 - 0.00031 19.4 6.0 0.00031 19.4 4.2 1.4 1 1 0 1 1 1 1 Golgin subfamily A member 5 DUF948 PF06103.6 EIE87425.1 - 0.0054 16.5 2.3 0.0095 15.7 1.6 1.3 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF948) DivIC PF04977.10 EIE87425.1 - 0.011 15.1 3.0 0.026 14.0 2.1 1.6 1 0 0 1 1 1 0 Septum formation initiator Spc24 PF08286.6 EIE87425.1 - 0.021 14.4 1.9 0.047 13.3 1.3 1.7 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Zn_Tnp_IS1 PF03811.8 EIE87425.1 - 0.021 14.2 4.5 0.048 13.1 3.1 1.6 1 0 0 1 1 1 0 InsA N-terminal domain CCDC144C PF14915.1 EIE87425.1 - 0.022 13.7 12.0 0.028 13.3 8.3 1.1 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region FliJ PF02050.11 EIE87425.1 - 0.023 14.7 6.9 0.023 14.7 4.8 1.8 2 0 0 2 2 2 0 Flagellar FliJ protein YPEB PF14620.1 EIE87425.1 - 0.03 13.3 2.9 0.036 13.0 2.0 1.1 1 0 0 1 1 1 0 YpeB sporulation DUF3450 PF11932.3 EIE87425.1 - 0.033 13.4 10.7 0.06 12.6 7.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) zf-CCHC PF00098.18 EIE87425.1 - 0.037 13.9 0.3 0.037 13.9 0.2 2.0 2 0 0 2 2 1 0 Zinc knuckle TBPIP PF07106.8 EIE87425.1 - 0.04 13.4 5.8 0.086 12.3 4.0 1.5 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) APG6 PF04111.7 EIE87425.1 - 0.041 12.9 4.9 0.051 12.6 3.4 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 COG2 PF06148.6 EIE87425.1 - 0.046 13.5 0.5 0.11 12.4 0.3 1.5 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Filament PF00038.16 EIE87425.1 - 0.046 13.1 5.7 0.081 12.3 4.0 1.4 1 0 0 1 1 1 0 Intermediate filament protein DUF641 PF04859.7 EIE87425.1 - 0.064 13.0 2.9 0.15 11.8 2.0 1.6 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Macoilin PF09726.4 EIE87425.1 - 0.072 11.3 6.8 0.079 11.2 4.7 1.0 1 0 0 1 1 1 0 Transmembrane protein Bap31 PF05529.7 EIE87425.1 - 0.086 12.2 3.0 0.15 11.5 2.1 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like TMF_DNA_bd PF12329.3 EIE87425.1 - 0.087 12.6 3.7 0.18 11.6 2.6 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF4515 PF14988.1 EIE87425.1 - 0.11 12.1 10.0 0.24 11.0 6.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4515) DUF904 PF06005.7 EIE87425.1 - 0.11 12.8 4.1 0.059 13.6 1.2 1.9 2 0 0 2 2 1 0 Protein of unknown function (DUF904) Zn_Tnp_IS1595 PF12760.2 EIE87425.1 - 0.19 11.5 3.9 0.46 10.3 2.7 1.6 1 0 0 1 1 1 0 Transposase zinc-ribbon domain GrpE PF01025.14 EIE87425.1 - 0.21 11.1 4.1 0.47 9.9 2.8 1.5 1 0 0 1 1 1 0 GrpE MutS_IV PF05190.13 EIE87425.1 - 0.21 11.7 2.2 2.2 8.4 0.1 2.7 3 0 0 3 3 3 0 MutS family domain IV DUF4407 PF14362.1 EIE87425.1 - 0.22 10.4 5.9 0.31 9.9 4.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Zn-ribbon_8 PF09723.5 EIE87425.1 - 0.24 11.3 5.8 8.6 6.4 0.0 3.1 2 1 0 2 2 2 0 Zinc ribbon domain DUF4140 PF13600.1 EIE87425.1 - 0.26 11.7 5.2 0.27 11.7 1.5 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) V_ATPase_I PF01496.14 EIE87425.1 - 0.32 8.7 4.1 0.37 8.5 2.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HR1 PF02185.11 EIE87425.1 - 0.5 10.1 7.9 0.13 12.0 2.8 2.1 2 0 0 2 2 1 0 Hr1 repeat ADK_lid PF05191.9 EIE87425.1 - 0.69 9.6 3.5 1.9 8.2 2.4 1.8 1 0 0 1 1 1 0 Adenylate kinase, active site lid HAUS6_N PF14661.1 EIE87425.1 - 0.86 8.9 8.3 0.67 9.2 4.9 1.4 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus ADIP PF11559.3 EIE87425.1 - 1.6 8.5 15.0 3.7 7.4 8.6 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding zf-ISL3 PF14690.1 EIE87425.1 - 1.9 8.5 6.6 1.2 9.2 2.8 2.0 1 1 1 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 DUF2316 PF10078.4 EIE87425.1 - 2.3 8.2 5.7 0.96 9.4 1.8 1.9 2 1 0 2 2 1 0 Uncharacterized protein conserved in bacteria (DUF2316) TPR_MLP1_2 PF07926.7 EIE87425.1 - 2.4 7.9 12.4 4.1 7.1 8.5 1.6 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein TFIIS_C PF01096.13 EIE87425.1 - 2.4 7.8 5.3 6.4 6.5 2.7 2.5 2 1 0 2 2 1 0 Transcription factor S-II (TFIIS) TEX13 PF15186.1 EIE87425.1 - 2.4 7.7 8.0 2.9 7.4 3.8 2.1 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family DUF972 PF06156.8 EIE87425.1 - 2.7 8.3 6.5 7 7.0 4.2 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF972) zf-RVT PF13966.1 EIE87426.1 - 0.00014 22.0 1.3 0.00078 19.7 0.5 2.2 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase PAN_1 PF00024.21 EIE87427.1 - 0.081 12.6 0.0 2.9 7.6 0.0 2.3 2 0 0 2 2 2 0 PAN domain DDE_3 PF13358.1 EIE87428.1 - 3.2e-13 49.6 0.2 4.3e-13 49.2 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease TMF_TATA_bd PF12325.3 EIE87431.1 - 1.1e-05 25.1 1.3 2e-05 24.2 0.9 1.4 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding DivIVA PF05103.8 EIE87431.1 - 0.00012 22.1 4.0 0.00012 22.1 2.7 2.0 3 0 0 3 3 2 1 DivIVA protein CENP-F_leu_zip PF10473.4 EIE87431.1 - 0.00013 21.8 4.3 0.00028 20.7 3.0 1.5 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2296 PF10058.4 EIE87431.1 - 0.00018 21.1 0.7 0.00042 19.9 0.5 1.6 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) Golgin_A5 PF09787.4 EIE87431.1 - 0.00027 19.6 6.6 0.00035 19.2 4.6 1.3 1 0 0 1 1 1 1 Golgin subfamily A member 5 DUF948 PF06103.6 EIE87431.1 - 0.0054 16.5 2.3 0.0095 15.7 1.6 1.3 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF948) DivIC PF04977.10 EIE87431.1 - 0.011 15.2 3.0 0.026 14.0 2.1 1.6 1 0 0 1 1 1 0 Septum formation initiator CCDC144C PF14915.1 EIE87431.1 - 0.016 14.1 12.0 0.021 13.7 8.3 1.1 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region Zn_Tnp_IS1 PF03811.8 EIE87431.1 - 0.02 14.3 4.5 0.048 13.1 3.1 1.7 1 0 0 1 1 1 0 InsA N-terminal domain FliJ PF02050.11 EIE87431.1 - 0.023 14.7 6.9 0.023 14.7 4.8 1.8 2 0 0 2 2 2 0 Flagellar FliJ protein Filament PF00038.16 EIE87431.1 - 0.033 13.6 5.2 0.056 12.8 3.6 1.3 1 0 0 1 1 1 0 Intermediate filament protein DUF3450 PF11932.3 EIE87431.1 - 0.035 13.3 10.7 0.06 12.6 7.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) zf-CCHC PF00098.18 EIE87431.1 - 0.037 13.9 0.3 0.037 13.9 0.2 1.9 2 0 0 2 2 1 0 Zinc knuckle YPEB PF14620.1 EIE87431.1 - 0.038 13.0 2.5 0.045 12.7 1.7 1.2 1 0 0 1 1 1 0 YpeB sporulation APG6 PF04111.7 EIE87431.1 - 0.04 12.9 4.3 0.047 12.7 3.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 COG2 PF06148.6 EIE87431.1 - 0.052 13.4 0.7 0.12 12.2 0.5 1.6 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF641 PF04859.7 EIE87431.1 - 0.065 12.9 2.9 0.15 11.8 2.0 1.6 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) HAUS6_N PF14661.1 EIE87431.1 - 0.073 12.4 4.7 0.12 11.6 3.2 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus TBPIP PF07106.8 EIE87431.1 - 0.073 12.6 6.6 0.15 11.5 4.6 1.5 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Bap31 PF05529.7 EIE87431.1 - 0.085 12.3 3.0 0.15 11.5 2.1 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like TMF_DNA_bd PF12329.3 EIE87431.1 - 0.086 12.6 3.7 0.18 11.6 2.6 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF4515 PF14988.1 EIE87431.1 - 0.12 12.0 9.9 0.26 10.9 6.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4515) Zn_Tnp_IS1595 PF12760.2 EIE87431.1 - 0.19 11.5 3.9 0.46 10.3 2.7 1.7 1 0 0 1 1 1 0 Transposase zinc-ribbon domain DUF4407 PF14362.1 EIE87431.1 - 0.2 10.6 5.9 0.28 10.1 4.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MutS_IV PF05190.13 EIE87431.1 - 0.21 11.7 2.2 2.2 8.4 0.1 2.8 3 0 0 3 3 3 0 MutS family domain IV Macoilin PF09726.4 EIE87431.1 - 0.21 9.8 6.4 0.22 9.7 4.4 1.1 1 0 0 1 1 1 0 Transmembrane protein Zn-ribbon_8 PF09723.5 EIE87431.1 - 0.22 11.5 5.8 8.6 6.4 0.0 3.1 2 1 0 2 2 2 0 Zinc ribbon domain GrpE PF01025.14 EIE87431.1 - 0.22 11.0 4.1 0.47 9.9 2.8 1.5 1 0 0 1 1 1 0 GrpE DUF4140 PF13600.1 EIE87431.1 - 0.26 11.7 5.6 0.27 11.7 1.5 2.3 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Spc24 PF08286.6 EIE87431.1 - 0.29 10.8 5.6 0.43 10.2 3.6 1.7 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 V_ATPase_I PF01496.14 EIE87431.1 - 0.29 8.9 4.0 0.34 8.6 2.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HR1 PF02185.11 EIE87431.1 - 0.66 9.7 8.2 0.13 12.0 2.8 2.1 2 0 0 2 2 1 0 Hr1 repeat ADK_lid PF05191.9 EIE87431.1 - 0.69 9.6 3.5 1.9 8.2 2.4 1.8 1 0 0 1 1 1 0 Adenylate kinase, active site lid DUF2316 PF10078.4 EIE87431.1 - 1.6 8.8 5.3 0.96 9.4 1.8 2.0 2 1 0 2 2 1 0 Uncharacterized protein conserved in bacteria (DUF2316) zf-ISL3 PF14690.1 EIE87431.1 - 1.8 8.6 6.6 1.2 9.2 2.8 2.0 1 1 1 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 ADIP PF11559.3 EIE87431.1 - 2 8.3 15.4 3.7 7.4 8.6 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding TPR_MLP1_2 PF07926.7 EIE87431.1 - 2.3 7.9 12.3 3.9 7.2 8.5 1.6 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF972 PF06156.8 EIE87431.1 - 2.5 8.4 6.2 4.9 7.5 3.7 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF972) TEX13 PF15186.1 EIE87431.1 - 3.2 7.3 8.3 2.9 7.4 3.8 2.1 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family DUF904 PF06005.7 EIE87431.1 - 3.8 7.8 9.2 11 6.3 6.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF904) Cytochrom_B561 PF03188.11 EIE87432.1 - 1e-16 61.0 7.8 1.3e-16 60.7 5.4 1.1 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2427 PF10348.4 EIE87432.1 - 0.0037 16.8 2.0 0.0037 16.8 1.4 1.8 2 1 0 2 2 2 1 Domain of unknown function (DUF2427) PepSY_TM_2 PF13703.1 EIE87432.1 - 0.01 15.9 3.1 0.63 10.2 0.6 2.9 2 1 0 2 2 2 0 PepSY-associated TM helix PetG PF02529.10 EIE87432.1 - 0.033 13.7 0.1 0.08 12.4 0.0 1.6 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit 5 PepSY_TM_1 PF13172.1 EIE87432.1 - 0.17 11.6 0.6 0.17 11.6 0.4 2.9 3 0 0 3 3 3 0 PepSY-associated TM helix PAXIP1_C PF15364.1 EIE87433.1 - 0.0013 18.7 0.4 0.0015 18.4 0.3 1.1 1 0 0 1 1 1 1 PAXIP1-associated-protein-1 C term PTIP binding protein CBFD_NFYB_HMF PF00808.18 EIE87433.1 - 0.0058 16.6 0.1 0.015 15.3 0.1 1.7 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone RNA_pol_Rpc82 PF05645.8 EIE87435.1 - 2.4e-17 63.3 0.5 2.1e-16 60.2 0.1 2.1 1 1 1 2 2 2 2 RNA polymerase III subunit RPC82 TrmB PF01978.14 EIE87435.1 - 0.00031 20.4 0.0 0.0057 16.3 0.0 2.8 3 0 0 3 3 3 1 Sugar-specific transcriptional regulator TrmB TFIIE_alpha PF02002.12 EIE87435.1 - 0.00046 19.6 1.1 0.0016 17.9 0.1 2.5 2 1 1 3 3 3 1 TFIIE alpha subunit HTH_9 PF08221.6 EIE87435.1 - 0.071 12.9 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain G-patch PF01585.18 EIE87436.1 - 5.1e-16 58.1 2.6 1.1e-15 57.1 1.8 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EIE87436.1 - 6e-07 29.2 0.3 6e-07 29.2 0.2 2.5 2 0 0 2 2 2 1 DExH-box splicing factor binding site zf-met PF12874.2 EIE87436.1 - 4.6e-06 26.6 1.2 9.9e-06 25.5 0.8 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EIE87436.1 - 2.1e-05 24.4 6.9 5.2e-05 23.2 4.8 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding Caldesmon PF02029.10 EIE87436.1 - 0.0023 16.4 2.7 0.0023 16.4 1.9 2.1 2 0 0 2 2 2 1 Caldesmon zf-C2H2_6 PF13912.1 EIE87436.1 - 0.005 16.6 1.7 0.0093 15.8 1.2 1.5 1 0 0 1 1 1 1 C2H2-type zinc finger zf-DBF PF07535.7 EIE87436.1 - 0.018 14.6 4.0 0.038 13.6 2.8 1.5 1 0 0 1 1 1 0 DBF zinc finger Evr1_Alr PF04777.8 EIE87436.1 - 0.11 12.3 1.2 0.33 10.8 0.8 1.8 1 0 0 1 1 1 0 Erv1 / Alr family zf-C2H2_4 PF13894.1 EIE87436.1 - 0.12 12.7 1.5 0.25 11.7 1.1 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EIE87436.1 - 0.13 12.6 2.0 0.3 11.5 1.4 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 EIE87436.1 - 2.6 8.2 10.2 0.37 10.9 4.0 1.9 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) ResIII PF04851.10 EIE87437.1 - 5.8e-09 36.0 1.5 4.7e-08 33.0 0.0 2.9 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EIE87437.1 - 0.00012 21.8 0.2 0.00049 19.8 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RhoGAP PF00620.22 EIE87438.1 - 3.6e-45 153.2 0.4 9.1e-45 151.9 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.18 EIE87438.1 - 6.2e-13 48.7 3.8 1.1e-11 44.8 0.4 2.9 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain BACK PF07707.10 EIE87438.1 - 0.054 13.3 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 BTB And C-terminal Kelch 4F5 PF04419.9 EIE87439.1 - 7.6e-09 36.1 11.7 7.6e-09 36.1 8.1 2.2 2 0 0 2 2 2 1 4F5 protein family Ribosomal_L10 PF00466.15 EIE87440.1 - 1.9e-13 50.1 0.0 3.1e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 DUF4168 PF13767.1 EIE87440.1 - 0.0023 18.5 0.1 0.0044 17.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4168) WD40 PF00400.27 EIE87441.1 - 2.4e-19 68.4 6.9 7.6e-08 31.9 0.1 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat DUF1654 PF07867.6 EIE87441.1 - 0.062 12.6 0.1 0.15 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1654) tRNA-synt_1 PF00133.17 EIE87442.1 - 1.8e-223 742.9 0.1 3.3e-223 742.0 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EIE87442.1 - 3.4e-29 101.5 0.1 1.9e-28 99.1 0.0 2.1 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EIE87442.1 - 4.8e-20 71.5 2.0 7.9e-09 34.6 0.2 4.3 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 EIE87442.1 - 0.0069 15.5 0.0 0.02 14.0 0.0 1.8 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Aldo_ket_red PF00248.16 EIE87443.1 - 2.7e-60 203.6 0.0 3.1e-60 203.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Coatomer_E PF04733.9 EIE87444.1 - 1.1e-86 290.5 4.6 1.3e-86 290.3 3.2 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.1 EIE87444.1 - 9.1e-08 32.3 8.9 0.00047 20.4 0.3 4.5 3 1 1 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 EIE87444.1 - 0.00013 22.0 8.4 0.17 12.0 0.3 4.3 2 2 3 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EIE87444.1 - 0.0011 18.9 2.3 0.014 15.3 0.5 3.3 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 EIE87444.1 - 0.0016 18.8 3.1 0.11 13.2 0.0 4.1 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 EIE87444.1 - 0.0024 18.4 3.1 0.012 16.2 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 EIE87444.1 - 0.0038 16.8 2.1 0.013 15.1 0.0 2.9 2 1 1 3 3 3 1 TPR repeat TPR_2 PF07719.12 EIE87444.1 - 0.091 12.7 0.1 0.091 12.7 0.0 4.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.9 EIE87444.1 - 0.34 11.4 1.7 8.4 7.1 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat CMS1 PF14617.1 EIE87445.1 - 0.0013 17.8 6.4 0.0021 17.2 4.4 1.3 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit Draxin PF15550.1 EIE87445.1 - 0.052 13.2 5.1 0.07 12.7 3.5 1.1 1 0 0 1 1 1 0 Draxin DUF3043 PF11241.3 EIE87445.1 - 1.5 8.3 13.3 2.9 7.4 9.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) GAGA_bind PF06217.7 EIE87445.1 - 3 7.7 10.1 4.3 7.2 7.0 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family HTH_24 PF13412.1 EIE87448.1 - 0.0069 15.7 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_17 PF12728.2 EIE87448.1 - 0.027 14.7 0.0 0.045 14.0 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.1 EIE87448.1 - 0.08 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain HTH_1 PF00126.22 EIE87448.1 - 0.094 12.4 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family SpoIIID PF12116.3 EIE87448.1 - 0.11 12.5 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Stage III sporulation protein D Sigma70_r4_2 PF08281.7 EIE87448.1 - 0.11 11.9 0.1 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 DUF746 PF05344.6 EIE87448.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF746) HTH_28 PF13518.1 EIE87448.1 - 0.12 12.4 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain PTR2 PF00854.16 EIE87449.1 - 2e-57 194.6 9.3 5.2e-57 193.3 6.5 1.6 1 1 0 1 1 1 1 POT family zf-RVT PF13966.1 EIE87450.1 - 8.9e-08 32.3 3.1 2.2e-07 31.0 2.1 1.7 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Hamartin PF04388.7 EIE87451.1 - 8e-16 57.8 38.3 2.7e-06 26.3 20.2 4.4 2 2 1 3 3 3 3 Hamartin protein Laminin_II PF06009.7 EIE87451.1 - 2.2 8.0 23.8 0.97 9.1 3.0 4.0 2 1 0 4 4 4 0 Laminin Domain II NPV_P10 PF05531.7 EIE87451.1 - 7.4 6.9 17.5 1.2 9.4 1.2 4.2 2 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein Retrotrans_gag PF03732.12 EIE87452.1 - 0.00028 20.9 0.0 0.0033 17.4 0.0 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein DUF2385 PF09539.5 EIE87452.1 - 0.059 13.7 0.0 0.17 12.2 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2385) Phage_integrase PF00589.17 EIE87453.1 - 0.00065 19.4 0.0 0.001 18.8 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family MBD PF01429.14 EIE87453.1 - 0.0048 16.3 0.0 0.005 16.3 0.0 1.2 1 0 0 1 1 1 1 Methyl-CpG binding domain Eapp_C PF10238.4 EIE87453.1 - 0.12 12.2 0.9 0.13 12.1 0.6 1.2 1 0 0 1 1 1 0 E2F-associated phosphoprotein Phage_int_SAM_1 PF02899.12 EIE87454.1 - 0.0027 17.8 1.0 0.0053 16.8 0.2 1.8 2 0 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Xol-1_N PF09108.5 EIE87454.1 - 0.043 13.4 0.0 0.075 12.7 0.0 1.4 1 0 0 1 1 1 0 Switch protein XOL-1, N-terminal HTH_Tnp_Tc3_2 PF01498.13 EIE87455.1 - 2e-12 47.0 0.3 6.1e-12 45.4 0.1 2.0 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.1 EIE87455.1 - 3.4e-12 46.3 0.0 5.2e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 EIE87455.1 - 8.4e-06 25.9 0.2 1.6e-05 25.0 0.1 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EIE87455.1 - 0.0001 21.8 0.7 0.00057 19.4 0.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_7 PF02796.10 EIE87455.1 - 0.00095 18.9 0.1 0.074 12.9 0.0 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_Tnp_IS630 PF01710.11 EIE87455.1 - 0.021 14.4 0.4 0.059 13.0 0.0 1.9 2 0 0 2 2 2 0 Transposase HTH_28 PF13518.1 EIE87455.1 - 0.049 13.6 0.4 0.19 11.7 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain DUF2110 PF09883.4 EIE87455.1 - 0.076 12.6 0.4 0.47 10.0 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2110) Lzipper-MIP1 PF14389.1 EIE87457.1 - 0.0049 16.9 0.4 0.013 15.5 0.3 1.7 1 0 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 ChaB PF06150.7 EIE87457.1 - 0.069 12.9 0.6 0.25 11.1 0.1 2.2 2 0 0 2 2 2 0 ChaB IncA PF04156.9 EIE87457.1 - 0.17 11.5 1.2 0.28 10.7 0.9 1.4 1 0 0 1 1 1 0 IncA protein DUF4404 PF14357.1 EIE87457.1 - 0.21 11.9 1.9 5.7 7.4 0.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) SRR PF07709.6 EIE87457.1 - 0.23 11.7 4.4 5.5 7.6 0.0 3.5 3 0 0 3 3 3 0 Seven Residue Repeat Transposase_21 PF02992.9 EIE87458.1 - 5.4e-23 81.2 0.1 5.4e-23 81.2 0.1 1.6 2 0 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.1 EIE87458.1 - 5.4e-05 22.6 0.3 0.00012 21.5 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) DUF1759 PF03564.10 EIE87459.1 - 0.0023 17.7 0.3 0.0023 17.7 0.2 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1759) RVT_1 PF00078.22 EIE87460.1 - 6e-10 38.8 0.0 1.1e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease PF09668.5 EIE87460.1 - 4.4e-07 29.4 0.0 9.2e-07 28.4 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 EIE87460.1 - 5.5e-06 26.7 0.0 1.3e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 EIE87460.1 - 0.00014 21.6 0.1 0.00059 19.7 0.1 2.2 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.6 EIE87460.1 - 0.00074 19.4 0.0 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EIE87460.1 - 0.023 14.5 0.0 0.054 13.3 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Phage_HK97_TLTM PF06120.6 EIE87460.1 - 0.052 12.8 3.5 0.079 12.2 2.4 1.2 1 0 0 1 1 1 0 Tail length tape measure protein HTH_Tnp_Tc3_2 PF01498.13 EIE87461.1 - 7.5e-09 35.5 0.5 1.5e-08 34.5 0.3 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.1 EIE87461.1 - 0.0091 15.7 0.0 0.037 13.7 0.0 1.9 1 1 0 2 2 2 1 DDE superfamily endonuclease HTH_29 PF13551.1 EIE87461.1 - 0.046 13.8 0.1 0.11 12.6 0.0 1.7 2 0 0 2 2 2 0 Winged helix-turn helix DDE_3 PF13358.1 EIE87462.1 - 2.3e-12 46.8 0.6 5.7e-12 45.5 0.4 1.7 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE87462.1 - 5.5e-08 32.7 0.3 5.5e-08 32.7 0.2 2.3 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 EIE87462.1 - 0.00055 20.0 1.9 0.0013 18.8 1.3 1.7 1 1 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_ISL3 PF13542.1 EIE87462.1 - 0.033 13.3 0.8 0.033 13.3 0.5 2.4 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 rve PF00665.21 EIE87462.1 - 0.086 12.9 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain HTH_32 PF13565.1 EIE87462.1 - 0.094 13.5 1.0 0.094 13.5 0.7 2.2 3 0 0 3 3 3 0 Homeodomain-like domain HTH_21 PF13276.1 EIE87462.1 - 0.22 11.5 2.4 0.87 9.6 0.1 2.3 2 0 0 2 2 2 0 HTH-like domain HTH_23 PF13384.1 EIE87462.1 - 0.23 11.1 2.9 2.6 7.8 0.2 2.5 2 0 0 2 2 2 0 Homeodomain-like domain DUF1033 PF06279.6 EIE87462.1 - 1.2 8.9 6.9 0.34 10.7 0.2 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF1033) NFRKB_winged PF14465.1 EIE87462.1 - 2.8 7.8 6.3 5.8 6.8 0.3 2.9 2 2 1 3 3 3 0 NFRKB Winged Helix-like DDE_3 PF13358.1 EIE87463.1 - 1e-09 38.2 0.9 1.1e-09 38.2 0.6 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE87464.1 - 4.1e-27 94.6 0.0 6.8e-27 93.9 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 EIE87464.1 - 2.3e-05 23.8 0.0 5.3e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain DUF3627 PF12299.3 EIE87465.1 - 0.022 14.8 0.2 0.022 14.8 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3627) DCP2 PF05026.8 EIE87465.1 - 0.053 13.4 1.9 1.2 9.1 0.4 2.2 2 0 0 2 2 2 0 Dcp2, box A domain MotCF PF09158.5 EIE87465.1 - 0.07 12.8 1.2 0.098 12.3 0.8 1.3 1 0 0 1 1 1 0 Bacteriophage T4 MotA, C-terminal MTS_N PF08468.6 EIE87465.1 - 0.11 12.3 2.2 0.16 11.7 1.6 1.2 1 0 0 1 1 1 0 Methyltransferase small domain N-terminal DDE_3 PF13358.1 EIE87466.1 - 1.7e-16 60.2 0.0 2.5e-16 59.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE87466.1 - 8.2e-10 38.6 2.1 5e-09 36.0 0.9 2.3 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.1 EIE87466.1 - 0.00047 19.7 0.0 0.0012 18.4 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_11 PF08279.7 EIE87466.1 - 0.00068 19.2 0.0 0.0019 17.8 0.0 1.7 1 0 0 1 1 1 1 HTH domain HTH_IclR PF09339.5 EIE87466.1 - 0.00075 19.0 0.0 0.0015 18.0 0.0 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_7 PF02796.10 EIE87466.1 - 0.0032 17.2 0.2 0.061 13.1 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_32 PF13565.1 EIE87466.1 - 0.0039 17.9 0.8 3.2 8.6 0.0 2.9 2 0 0 2 2 2 1 Homeodomain-like domain HTH_36 PF13730.1 EIE87466.1 - 0.0039 17.2 0.4 0.25 11.5 0.0 3.0 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_38 PF13936.1 EIE87466.1 - 0.0073 15.8 0.0 0.016 14.7 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.7 EIE87466.1 - 0.011 15.1 0.0 0.03 13.7 0.0 1.7 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_AsnC-type PF13404.1 EIE87466.1 - 0.015 14.8 0.0 0.032 13.7 0.0 1.5 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_29 PF13551.1 EIE87466.1 - 0.017 15.2 0.1 0.11 12.6 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_4 PF13613.1 EIE87466.1 - 0.02 14.4 0.0 0.3 10.6 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix of DDE superfamily endonuclease UPF0122 PF04297.9 EIE87466.1 - 0.04 13.9 0.2 0.11 12.5 0.0 1.7 2 0 0 2 2 2 0 Putative helix-turn-helix protein, YlxM / p13 like Sigma70_r4 PF04545.11 EIE87466.1 - 0.041 13.2 0.0 0.087 12.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_24 PF13412.1 EIE87466.1 - 0.041 13.2 0.0 0.095 12.1 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_17 PF12728.2 EIE87466.1 - 0.048 13.9 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain GerE PF00196.14 EIE87466.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family HTH_Tnp_Tc3_2 PF01498.13 EIE87467.1 - 2.6e-06 27.3 0.2 5.9e-06 26.2 0.2 1.6 1 0 0 1 1 1 1 Transposase Baculo_8kDa PF06096.6 EIE87467.1 - 0.016 15.0 0.2 0.047 13.5 0.1 1.7 1 0 0 1 1 1 0 Baculoviridae 8.2 KDa protein HTH_32 PF13565.1 EIE87467.1 - 0.13 13.0 0.3 13 6.6 0.0 2.4 1 1 1 2 2 2 0 Homeodomain-like domain rve PF00665.21 EIE87470.1 - 4.1e-12 46.2 0.0 2e-11 44.0 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain YcgR_2 PF12945.2 EIE87470.1 - 0.0085 15.9 0.0 0.019 14.8 0.0 1.6 1 0 0 1 1 1 1 Flagellar protein YcgR rve_3 PF13683.1 EIE87470.1 - 0.073 12.6 0.0 0.21 11.1 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain DUF4065 PF13274.1 EIE87470.1 - 0.077 13.7 0.1 0.27 11.9 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF4065) Retrotrans_gag PF03732.12 EIE87471.1 - 6.9e-05 22.8 0.6 0.0002 21.3 0.1 2.0 2 0 0 2 2 2 1 Retrotransposon gag protein UBN2_2 PF14227.1 EIE87471.1 - 0.061 12.8 0.2 0.15 11.6 0.1 1.6 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type rve PF00665.21 EIE87472.1 - 1.6e-20 73.3 0.0 5.1e-20 71.7 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE87472.1 - 2.4e-11 43.4 0.3 5.2e-11 42.3 0.2 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE87472.1 - 1.4e-10 40.6 0.4 3.6e-10 39.3 0.3 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Transposase_21 PF02992.9 EIE87474.1 - 6.5e-21 74.4 0.0 6.5e-21 74.4 0.0 1.8 2 0 0 2 2 2 1 Transposase family tnp2 DUF1258 PF06869.7 EIE87474.1 - 0.0051 15.9 0.0 0.011 14.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) 3HCDH_N PF02737.13 EIE87474.1 - 0.049 13.2 0.0 0.089 12.4 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF4218 PF13960.1 EIE87474.1 - 0.091 12.2 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) Rep_fac_C PF08542.6 EIE87474.1 - 0.097 12.6 0.0 0.28 11.2 0.0 1.7 1 0 0 1 1 1 0 Replication factor C C-terminal domain DDE_3 PF13358.1 EIE87475.1 - 7.9e-18 64.6 0.0 1.7e-17 63.5 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE87475.1 - 4.9e-08 32.9 3.1 6.8e-08 32.4 0.5 2.5 2 1 1 3 3 3 1 Transposase HTH_23 PF13384.1 EIE87475.1 - 0.0003 20.3 0.0 0.00067 19.2 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_7 PF02796.10 EIE87475.1 - 0.0053 16.5 0.1 0.011 15.6 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase NUDIX_4 PF14815.1 EIE87475.1 - 0.015 14.7 0.3 0.027 13.9 0.2 1.4 1 0 0 1 1 1 0 NUDIX domain Transposase_21 PF02992.9 EIE87476.1 - 8e-21 74.1 1.1 1e-20 73.8 0.0 1.7 2 0 0 2 2 2 1 Transposase family tnp2 DUF4616 PF15394.1 EIE87477.1 - 0.017 14.1 0.5 0.022 13.8 0.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4616) MRP-63 PF14978.1 EIE87477.1 - 0.067 13.6 0.3 0.12 12.7 0.1 1.5 1 1 0 1 1 1 0 Mitochondrial ribosome protein 63 DDE_3 PF13358.1 EIE87478.1 - 7.1e-19 67.9 0.0 9.6e-19 67.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE87478.1 - 0.017 15.2 0.0 0.034 14.2 0.0 1.6 1 1 0 1 1 1 0 Integrase core domain Myb_DNA-bind_5 PF13873.1 EIE87478.1 - 0.057 13.3 0.7 5.2 7.0 0.2 2.5 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain DUF1033 PF06279.6 EIE87478.1 - 0.067 13.0 0.3 0.11 12.2 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1033) DUF4029 PF13221.1 EIE87479.1 - 0.055 13.8 1.9 0.095 13.1 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4029) DDE_Tnp_1_5 PF13737.1 EIE87479.1 - 0.13 12.4 0.1 0.21 11.7 0.1 1.4 1 0 0 1 1 1 0 Transposase DDE domain DUF1703 PF08011.6 EIE87481.1 - 1.1 9.0 4.9 4 7.2 2.6 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1703) VIT1 PF01988.14 EIE87481.1 - 1.4 8.3 3.3 2.6 7.4 2.3 1.5 1 1 0 1 1 1 0 VIT family DUF4557 PF15101.1 EIE87481.1 - 1.9 8.2 5.4 2.7 7.8 3.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) rve PF00665.21 EIE87482.1 - 4.3e-23 81.7 0.0 1.2e-22 80.2 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.19 EIE87482.1 - 1.6e-08 34.0 0.1 3.1e-08 33.1 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 EIE87482.1 - 0.00049 19.4 1.6 0.00049 19.4 1.1 2.3 2 0 0 2 2 2 1 His(2)-Cys(2) zinc finger Tudor-knot PF11717.3 EIE87482.1 - 0.03 14.0 0.2 0.11 12.1 0.1 2.0 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain RVT_1 PF00078.22 EIE87483.1 - 4.7e-07 29.3 0.1 1e-06 28.3 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.12 EIE87483.1 - 6.2e-07 29.4 0.1 1.6e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein Asp_protease_2 PF13650.1 EIE87483.1 - 1.2e-05 25.6 0.0 2.6e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EIE87483.1 - 0.011 15.5 0.0 0.029 14.1 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease PF09668.5 EIE87483.1 - 0.032 13.8 0.0 0.066 12.7 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease DDE_3 PF13358.1 EIE87485.1 - 6.5e-18 64.8 0.0 1.4e-17 63.8 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE87485.1 - 2.6e-08 33.8 2.2 6.1e-08 32.6 0.5 2.4 1 1 1 2 2 2 1 Transposase NUDIX_4 PF14815.1 EIE87485.1 - 0.013 14.9 0.3 0.023 14.0 0.2 1.4 1 0 0 1 1 1 0 NUDIX domain DDE_3 PF13358.1 EIE87487.1 - 4.2e-13 49.2 0.1 5.7e-13 48.8 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE87487.1 - 0.017 15.2 0.0 0.027 14.5 0.0 1.4 1 0 0 1 1 1 0 Integrase core domain Zip PF02535.17 EIE87488.1 - 9.6e-59 198.9 13.8 1.5e-57 195.0 9.6 1.9 1 1 0 1 1 1 1 ZIP Zinc transporter SWIB PF02201.13 EIE87489.1 - 1.9e-38 129.9 3.3 7e-20 70.4 0.2 2.6 3 0 0 3 3 3 2 SWIB/MDM2 domain DEK_C PF08766.6 EIE87489.1 - 1.3e-10 40.8 0.4 4.1e-10 39.2 0.3 1.8 2 0 0 2 2 2 1 DEK C terminal domain Peptidase_C1 PF00112.18 EIE87489.1 - 0.0014 18.5 0.3 0.71 9.7 0.0 2.3 2 0 0 2 2 2 2 Papain family cysteine protease SRP54_N PF02881.14 EIE87489.1 - 0.067 13.3 0.2 0.51 10.4 0.1 2.5 3 0 0 3 3 3 0 SRP54-type protein, helical bundle domain FANCI_S3 PF14677.1 EIE87489.1 - 0.14 11.5 4.6 4.5 6.5 0.0 3.1 1 1 2 3 3 3 0 FANCI solenoid 3 Tubulin PF00091.20 EIE87489.1 - 0.82 9.4 3.5 8.4 6.1 0.3 2.8 2 1 1 3 3 3 0 Tubulin/FtsZ family, GTPase domain UBN2_3 PF14244.1 EIE87489.1 - 1.2 8.7 5.8 4.5 6.8 0.5 2.6 2 1 1 3 3 3 0 gag-polypeptide of LTR copia-type Cyclase PF04199.8 EIE87490.1 - 1.4e-16 60.6 0.0 2.2e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 Putative cyclase Ribosomal_L3 PF00297.17 EIE87491.1 - 2.7e-40 138.4 1.1 1.2e-38 133.0 0.7 2.1 1 1 0 1 1 1 1 Ribosomal protein L3 Fungal_trans PF04082.13 EIE87492.1 - 1.1e-24 86.7 2.7 1.1e-24 86.7 1.9 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Mito_carr PF00153.22 EIE87493.1 - 2.2e-51 171.5 4.5 4.1e-22 77.7 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein PFK PF00365.15 EIE87494.1 - 4.1e-176 583.7 6.3 3.9e-123 409.9 2.5 2.1 2 0 0 2 2 2 2 Phosphofructokinase DDE_Tnp_1_6 PF13751.1 EIE87494.1 - 0.12 12.4 0.0 0.42 10.6 0.0 1.9 2 0 0 2 2 2 0 Transposase DDE domain PIF1 PF05970.9 EIE87496.1 - 2.3e-108 362.4 0.0 3.3e-108 361.8 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.1 EIE87496.1 - 1.7e-62 210.4 0.0 3.6e-62 209.3 0.0 1.6 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.1 EIE87496.1 - 1.6e-05 24.5 0.0 5.1e-05 22.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 EIE87496.1 - 0.00027 20.8 0.0 0.0011 18.7 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EIE87496.1 - 0.0005 19.7 0.0 0.0013 18.4 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain Herpes_Helicase PF02689.9 EIE87496.1 - 0.0023 15.7 0.0 0.0038 15.0 0.0 1.2 1 0 0 1 1 1 1 Helicase AAA_5 PF07728.9 EIE87496.1 - 0.0075 16.0 0.0 0.021 14.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EIE87496.1 - 0.043 13.7 0.0 0.23 11.4 0.0 2.3 3 0 0 3 3 2 0 AAA ATPase domain TrwB_AAD_bind PF10412.4 EIE87496.1 - 0.047 12.3 0.0 0.077 11.5 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain T2SE PF00437.15 EIE87496.1 - 0.049 12.5 0.0 0.085 11.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.11 EIE87496.1 - 0.069 12.3 0.0 0.15 11.2 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein DAP3 PF10236.4 EIE87496.1 - 0.083 11.8 0.0 0.17 10.7 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 UvrD_C_2 PF13538.1 EIE87496.1 - 0.098 12.7 0.0 0.25 11.4 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Sds3 PF08598.6 EIE87497.1 - 0.025 14.1 0.0 0.03 13.8 0.0 1.1 1 0 0 1 1 1 0 Sds3-like ABC_tran PF00005.22 EIE87499.1 - 2.5e-35 121.7 0.1 2.4e-17 63.4 0.0 3.0 2 1 0 2 2 2 2 ABC transporter RLI PF04068.10 EIE87499.1 - 4.5e-15 54.9 5.6 1.2e-14 53.5 3.9 1.8 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.1 EIE87499.1 - 3.6e-12 46.8 13.4 0.0065 16.4 0.1 4.8 3 2 2 5 5 4 4 AAA domain SMC_N PF02463.14 EIE87499.1 - 3.8e-11 42.6 4.6 0.00084 18.6 0.3 3.8 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain Fer4 PF00037.22 EIE87499.1 - 1.4e-08 33.9 2.8 1.4e-08 33.9 1.9 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_15 PF13175.1 EIE87499.1 - 3.9e-07 29.4 3.0 0.88 8.5 0.1 4.2 3 1 1 4 4 4 1 AAA ATPase domain AAA_29 PF13555.1 EIE87499.1 - 1.5e-06 27.6 0.4 0.051 13.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain Fer4_6 PF12837.2 EIE87499.1 - 6.4e-06 25.8 11.0 1.2e-05 24.9 0.8 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_17 PF13207.1 EIE87499.1 - 6.5e-05 23.7 0.3 0.52 11.1 0.0 2.8 2 2 0 2 2 2 2 AAA domain DUF258 PF03193.11 EIE87499.1 - 7.4e-05 21.9 4.3 0.074 12.2 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_18 PF13238.1 EIE87499.1 - 0.00035 20.8 0.1 0.29 11.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EIE87499.1 - 0.00065 19.9 0.0 1.5 9.0 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 EIE87499.1 - 0.00076 19.8 0.1 0.056 13.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain Fer4_21 PF14697.1 EIE87499.1 - 0.00088 19.0 11.3 0.0016 18.2 7.8 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_16 PF13191.1 EIE87499.1 - 0.00092 19.2 0.2 0.11 12.4 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain Fer4_16 PF13484.1 EIE87499.1 - 0.0015 19.2 5.2 0.003 18.2 0.1 2.4 2 0 0 2 2 2 1 4Fe-4S double cluster binding domain Fer4_2 PF12797.2 EIE87499.1 - 0.0023 17.7 1.8 0.0023 17.7 1.2 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain VirE PF05272.6 EIE87499.1 - 0.0024 17.3 0.0 1 8.7 0.0 2.4 2 0 0 2 2 2 1 Virulence-associated protein E Miro PF08477.8 EIE87499.1 - 0.0033 17.8 0.1 0.43 11.0 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein AAA_22 PF13401.1 EIE87499.1 - 0.0037 17.4 0.0 0.48 10.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain Fer4_9 PF13187.1 EIE87499.1 - 0.004 17.3 10.8 0.01 16.0 7.5 1.8 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.2 EIE87499.1 - 0.0043 17.4 2.2 0.0043 17.4 1.5 2.0 1 1 2 3 3 3 2 4Fe-4S dicluster domain AAA_33 PF13671.1 EIE87499.1 - 0.0048 16.7 0.0 0.25 11.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EIE87499.1 - 0.0051 16.4 0.6 0.76 9.4 0.0 2.5 2 0 0 2 2 2 1 NACHT domain Thymidylate_kin PF02223.12 EIE87499.1 - 0.0055 16.1 0.2 4.8 6.5 0.0 3.3 3 0 0 3 3 3 0 Thymidylate kinase Rad17 PF03215.10 EIE87499.1 - 0.0058 15.3 0.0 0.091 11.4 0.0 2.1 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein RNA_helicase PF00910.17 EIE87499.1 - 0.0062 16.7 0.1 3.2 7.9 0.0 2.8 2 0 0 2 2 2 1 RNA helicase Fer4_10 PF13237.1 EIE87499.1 - 0.0069 16.1 1.6 0.0069 16.1 1.1 2.1 1 1 1 2 2 2 1 4Fe-4S dicluster domain MobB PF03205.9 EIE87499.1 - 0.0083 15.8 1.1 0.84 9.3 0.0 2.7 3 0 0 3 3 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.9 EIE87499.1 - 0.01 15.5 0.3 0.44 10.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) SRP54 PF00448.17 EIE87499.1 - 0.013 14.9 1.1 1.1 8.7 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain SbcCD_C PF13558.1 EIE87499.1 - 0.018 14.9 0.1 5 7.1 0.0 3.2 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.1 EIE87499.1 - 0.027 13.8 0.0 5.9 6.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 EIE87499.1 - 0.031 14.2 0.0 3 7.8 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase ArgK PF03308.11 EIE87499.1 - 0.061 12.0 0.1 2.6 6.7 0.0 2.3 2 0 0 2 2 2 0 ArgK protein AAA_28 PF13521.1 EIE87499.1 - 0.11 12.4 0.6 6.3 6.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 EIE87499.1 - 0.11 11.3 0.2 5.2 5.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_14 PF13173.1 EIE87499.1 - 0.12 12.2 0.6 11 5.9 0.0 3.0 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EIE87499.1 - 0.12 11.8 0.0 3.2 7.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.1 EIE87499.1 - 0.19 10.1 0.6 0.45 8.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain Fer4_4 PF12800.2 EIE87499.1 - 0.27 11.6 13.5 0.065 13.6 1.5 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain AAA_10 PF12846.2 EIE87499.1 - 0.27 10.6 1.8 10 5.4 0.0 2.8 3 0 0 3 3 3 0 AAA-like domain Fer4_8 PF13183.1 EIE87499.1 - 0.9 9.6 10.9 0.057 13.4 0.9 2.0 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.2 EIE87499.1 - 2.5 8.8 15.1 0.065 13.8 3.6 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_15 PF13459.1 EIE87499.1 - 3 8.4 7.8 0.11 13.0 0.6 2.2 2 0 0 2 2 1 0 4Fe-4S single cluster domain Aminotran_1_2 PF00155.16 EIE87500.1 - 5.3e-78 262.5 0.0 7.1e-78 262.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EIE87500.1 - 7.5e-06 24.4 0.0 1.5e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EIE87500.1 - 5.6e-05 22.0 0.0 0.00022 20.0 0.0 1.9 1 1 1 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EIE87500.1 - 0.00093 18.4 0.0 0.0019 17.3 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Scm3 PF10384.4 EIE87500.1 - 0.28 10.6 1.4 2.1 7.9 0.0 2.8 3 0 0 3 3 3 0 Centromere protein Scm3 Ank_2 PF12796.2 EIE87502.1 - 2e-21 76.0 2.1 1.3e-13 51.0 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EIE87502.1 - 3.1e-17 62.5 2.8 1.1e-08 35.3 0.1 4.2 2 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 EIE87502.1 - 8.9e-14 50.5 5.8 9.7e-07 28.3 0.2 5.1 4 2 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 EIE87502.1 - 2.3e-12 46.7 2.4 4.4e-05 23.5 0.1 4.4 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIE87502.1 - 1.2e-11 43.6 1.7 5.4e-05 23.0 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeat RRM_1 PF00076.17 EIE87503.1 - 0.00027 20.5 6.1 0.09 12.4 0.5 4.1 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE87503.1 - 0.00027 20.6 0.0 0.047 13.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sugar_tr PF00083.19 EIE87504.1 - 3.7e-101 338.9 28.0 2.1e-98 329.8 19.4 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIE87504.1 - 7.1e-30 103.9 56.4 1.2e-25 90.0 16.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Fork_head PF00250.13 EIE87505.1 - 1e-28 99.2 0.3 2e-28 98.2 0.2 1.5 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 EIE87505.1 - 2.3e-11 43.6 0.0 4.6e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 FHA domain DUF1479 PF07350.7 EIE87505.1 - 0.00061 18.3 0.2 0.00075 18.0 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) UCH PF00443.24 EIE87506.1 - 1.9e-30 105.9 0.2 2.7e-30 105.3 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EIE87506.1 - 6.4e-13 48.6 0.3 1.3e-12 47.6 0.2 1.5 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 EIE87506.1 - 5.4e-05 22.7 0.3 0.00023 20.7 0.2 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RasGAP PF00616.14 EIE87507.1 - 1.3e-51 175.1 0.0 1.3e-51 175.1 0.0 2.2 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 EIE87507.1 - 7.7e-30 103.4 2.6 7.7e-30 103.4 1.8 2.8 3 0 0 3 3 3 1 RasGAP C-terminus DUF972 PF06156.8 EIE87507.1 - 0.005 17.1 7.0 0.12 12.7 0.3 3.0 2 0 0 2 2 2 2 Protein of unknown function (DUF972) DUF818 PF05677.7 EIE87507.1 - 0.014 14.1 0.0 0.027 13.1 0.0 1.4 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) MitMem_reg PF13012.1 EIE87507.1 - 0.83 9.7 7.4 0.65 10.1 0.4 2.9 3 0 0 3 3 3 0 Maintenance of mitochondrial structure and function GPI-anchored PF10342.4 EIE87508.1 - 1.2e-05 25.7 0.0 1.7e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family GATA PF00320.22 EIE87509.1 - 5.9e-16 57.5 3.4 5.9e-16 57.5 2.4 2.3 2 0 0 2 2 2 1 GATA zinc finger TF_Zn_Ribbon PF08271.7 EIE87509.1 - 0.0043 16.3 1.5 0.0089 15.3 1.0 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding DUF29 PF01724.11 EIE87509.1 - 0.034 13.9 1.7 0.047 13.5 0.4 1.7 1 1 0 2 2 2 0 Domain of unknown function DUF29 zf-RING_3 PF14369.1 EIE87509.1 - 0.37 10.8 4.1 0.19 11.7 0.4 2.3 2 0 0 2 2 2 0 zinc-finger eIF-5_eIF-2B PF01873.12 EIE87509.1 - 2.6 7.7 7.0 2.5 7.7 3.0 2.1 2 0 0 2 2 2 0 Domain found in IF2B/IF5 NDUFA12 PF05071.11 EIE87510.1 - 4e-10 40.0 1.9 6.6e-10 39.3 1.3 1.5 1 1 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 ADK PF00406.17 EIE87511.1 - 8.5e-60 201.0 0.0 1.1e-59 200.5 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 EIE87511.1 - 1.8e-15 56.2 0.0 3.8e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.1 EIE87511.1 - 0.0014 19.4 0.0 0.0033 18.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EIE87511.1 - 0.015 15.1 0.0 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EIE87511.1 - 0.029 14.6 0.0 0.08 13.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain SNARE PF05739.14 EIE87511.1 - 0.032 13.9 0.0 6 6.6 0.0 2.4 2 0 0 2 2 2 0 SNARE domain Zeta_toxin PF06414.7 EIE87511.1 - 0.077 12.0 0.1 0.16 11.0 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin NPV_P10 PF05531.7 EIE87511.1 - 0.15 12.2 0.8 6.3 7.1 0.0 2.9 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein SNF2_N PF00176.18 EIE87512.1 - 2.4e-73 246.5 0.0 4.3e-73 245.7 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EIE87512.1 - 1.4e-14 53.7 0.0 4e-14 52.2 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EIE87512.1 - 7.8e-08 31.4 0.0 1.5e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Arm PF00514.18 EIE87513.1 - 0.00017 21.2 5.7 0.049 13.4 0.1 5.1 5 0 0 5 5 5 3 Armadillo/beta-catenin-like repeat PP-binding PF00550.20 EIE87514.1 - 2.1e-13 50.3 0.1 2.5e-13 50.0 0.1 1.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 EIE87514.1 - 7.6e-07 29.0 0.3 9.8e-07 28.7 0.2 1.3 1 0 0 1 1 1 1 Acyl-carrier DUF1493 PF07377.7 EIE87514.1 - 0.12 12.4 0.1 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) AMP-binding PF00501.23 EIE87516.1 - 4.4e-70 236.1 0.1 5.3e-70 235.9 0.1 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EIE87516.1 - 9.3e-06 26.5 0.6 2.1e-05 25.3 0.1 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DDE_3 PF13358.1 EIE87517.1 - 4.9e-29 100.9 0.0 1e-28 99.9 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 EIE87517.1 - 4.2e-10 39.7 0.1 1.7e-09 37.8 0.0 1.9 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.1 EIE87517.1 - 4e-08 33.9 0.3 1.1e-07 32.5 0.0 2.0 2 0 0 2 2 1 1 Homeodomain-like domain HTH_23 PF13384.1 EIE87517.1 - 2.6e-07 30.0 1.8 4.3e-05 23.0 0.0 2.9 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.1 EIE87517.1 - 3.4e-07 30.1 2.9 1.7e-05 24.7 0.1 3.1 3 0 0 3 3 3 1 Helix-turn-helix domain rve PF00665.21 EIE87517.1 - 0.00035 20.6 0.0 0.0052 16.8 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain HTH_17 PF12728.2 EIE87517.1 - 0.0012 19.1 0.3 1.7 8.9 0.2 2.7 2 0 0 2 2 2 2 Helix-turn-helix domain DDE_1 PF03184.14 EIE87517.1 - 0.0015 17.7 0.0 0.031 13.4 0.0 2.4 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_1 PF01527.15 EIE87517.1 - 0.0051 16.7 1.1 0.014 15.3 0.1 2.0 2 0 0 2 2 2 1 Transposase HTH_Tnp_Tc3_2 PF01498.13 EIE87517.1 - 0.028 14.4 0.0 0.14 12.2 0.0 2.2 2 0 0 2 2 2 0 Transposase HTH_30 PF13556.1 EIE87517.1 - 0.075 12.6 0.6 0.2 11.2 0.1 1.9 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain HTH_Tnp_ISL3 PF13542.1 EIE87517.1 - 0.076 12.2 0.0 0.16 11.1 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 DDE_3 PF13358.1 EIE87518.1 - 4.9e-29 100.9 0.0 1e-28 99.9 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 EIE87518.1 - 4.2e-10 39.7 0.1 1.7e-09 37.8 0.0 1.9 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.1 EIE87518.1 - 4e-08 33.9 0.3 1.1e-07 32.5 0.0 2.0 2 0 0 2 2 1 1 Homeodomain-like domain HTH_23 PF13384.1 EIE87518.1 - 2.6e-07 30.0 1.8 4.3e-05 23.0 0.0 2.9 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.1 EIE87518.1 - 3.4e-07 30.1 2.9 1.7e-05 24.7 0.1 3.1 3 0 0 3 3 3 1 Helix-turn-helix domain rve PF00665.21 EIE87518.1 - 0.00035 20.6 0.0 0.0052 16.8 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain HTH_17 PF12728.2 EIE87518.1 - 0.0012 19.1 0.3 1.7 8.9 0.2 2.7 2 0 0 2 2 2 2 Helix-turn-helix domain DDE_1 PF03184.14 EIE87518.1 - 0.0015 17.7 0.0 0.031 13.4 0.0 2.4 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_1 PF01527.15 EIE87518.1 - 0.0051 16.7 1.1 0.014 15.3 0.1 2.0 2 0 0 2 2 2 1 Transposase HTH_Tnp_Tc3_2 PF01498.13 EIE87518.1 - 0.028 14.4 0.0 0.14 12.2 0.0 2.2 2 0 0 2 2 2 0 Transposase HTH_30 PF13556.1 EIE87518.1 - 0.075 12.6 0.6 0.2 11.2 0.1 1.9 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain HTH_Tnp_ISL3 PF13542.1 EIE87518.1 - 0.076 12.2 0.0 0.16 11.1 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 DUF2576 PF10845.3 EIE87519.1 - 0.023 13.8 0.0 0.034 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2576) AAA PF00004.24 EIE87521.1 - 4e-44 150.0 0.0 1e-43 148.6 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EIE87521.1 - 2.7e-07 30.6 0.0 5.8e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EIE87521.1 - 4.3e-07 29.7 0.1 2.7e-06 27.1 0.0 2.4 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EIE87521.1 - 2.7e-06 27.4 0.0 1.4e-05 25.2 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EIE87521.1 - 3.5e-06 27.2 0.0 0.00023 21.2 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EIE87521.1 - 6e-05 23.8 0.0 0.00017 22.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EIE87521.1 - 0.0001 21.4 0.0 0.00018 20.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EIE87521.1 - 0.00012 21.7 0.1 0.00028 20.5 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EIE87521.1 - 0.00038 19.9 0.0 0.00071 19.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 EIE87521.1 - 0.00097 17.9 0.0 0.0019 16.9 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 EIE87521.1 - 0.0015 18.4 0.0 0.0032 17.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EIE87521.1 - 0.0015 18.4 0.0 0.0029 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EIE87521.1 - 0.0029 16.7 0.0 0.0056 15.7 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_28 PF13521.1 EIE87521.1 - 0.0033 17.3 0.0 0.0065 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 EIE87521.1 - 0.0045 16.6 0.0 0.012 15.2 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EIE87521.1 - 0.0058 16.9 0.2 0.031 14.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EIE87521.1 - 0.0064 15.6 0.1 0.016 14.3 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI PhoH PF02562.11 EIE87521.1 - 0.0074 15.5 0.0 0.075 12.2 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein KaiC PF06745.8 EIE87521.1 - 0.0084 15.2 0.0 0.027 13.6 0.0 1.8 2 0 0 2 2 2 1 KaiC AAA_25 PF13481.1 EIE87521.1 - 0.015 14.6 0.1 0.11 11.8 0.0 2.0 1 1 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 EIE87521.1 - 0.017 14.6 0.0 0.094 12.1 0.0 2.2 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_24 PF13479.1 EIE87521.1 - 0.018 14.6 0.0 0.036 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 EIE87521.1 - 0.028 13.3 0.0 0.055 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RNA_helicase PF00910.17 EIE87521.1 - 0.032 14.4 0.0 0.057 13.5 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Parvo_NS1 PF01057.12 EIE87521.1 - 0.044 12.6 0.0 0.084 11.7 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.1 EIE87521.1 - 0.046 13.7 0.0 0.18 11.8 0.0 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain IncA PF04156.9 EIE87521.1 - 0.048 13.2 0.5 0.096 12.2 0.4 1.4 1 0 0 1 1 1 0 IncA protein DUF2072 PF09845.4 EIE87521.1 - 0.05 13.5 0.3 0.13 12.2 0.2 1.7 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) NACHT PF05729.7 EIE87521.1 - 0.087 12.4 0.0 0.52 9.9 0.0 2.1 1 1 1 2 2 2 0 NACHT domain ABC_tran PF00005.22 EIE87521.1 - 0.12 12.6 0.1 0.6 10.4 0.0 2.4 2 1 0 2 2 2 0 ABC transporter AIG1 PF04548.11 EIE87522.1 - 7.8e-07 28.4 0.1 2.1e-06 27.0 0.1 1.7 1 1 0 1 1 1 1 AIG1 family NUDIX-like PF09296.6 EIE87522.1 - 0.012 15.9 0.0 0.017 15.4 0.0 1.2 1 0 0 1 1 1 0 NADH pyrophosphatase-like rudimentary NUDIX domain Septin PF00735.13 EIE87522.1 - 0.012 14.6 0.0 0.019 13.9 0.0 1.3 1 0 0 1 1 1 0 Septin DUF1212 PF06738.7 EIE87524.1 - 4.1e-33 114.4 1.2 4.7e-33 114.2 0.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1212) DUF3815 PF12821.2 EIE87524.1 - 3.3 7.6 11.2 5.1 7.0 7.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3815) Bromodomain PF00439.20 EIE87525.1 - 9.6e-41 137.5 7.0 9.5e-22 76.7 1.5 2.9 2 0 0 2 2 2 2 Bromodomain Ank_5 PF13857.1 EIE87525.1 - 9.4e-11 41.5 0.0 1.4e-05 25.1 0.1 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EIE87525.1 - 1.2e-10 41.5 0.1 2.2e-10 40.7 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EIE87525.1 - 3.7e-10 39.0 0.0 1.4e-05 24.6 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 EIE87525.1 - 6.4e-07 29.7 0.2 0.00041 20.7 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIE87525.1 - 2.6e-06 27.1 0.1 0.00025 20.9 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeat RNA_pol_Rpb2_5 PF04567.12 EIE87525.1 - 0.13 12.2 0.9 21 5.1 0.0 2.6 2 0 0 2 2 2 0 RNA polymerase Rpb2, domain 5 AT_hook PF02178.14 EIE87525.1 - 0.2 11.4 3.2 0.6 9.9 2.2 1.9 1 0 0 1 1 1 0 AT hook motif Peptidase_S8 PF00082.17 EIE87526.1 - 1.2e-52 178.8 0.4 2.5e-52 177.7 0.3 1.6 1 0 0 1 1 1 1 Subtilase family PA PF02225.17 EIE87526.1 - 1.3e-14 53.7 0.1 4.3e-14 52.0 0.0 1.9 2 0 0 2 2 2 1 PA domain DUF1034 PF06280.7 EIE87526.1 - 7.7e-06 26.2 1.0 2.1e-05 24.9 0.7 1.7 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) Pkinase PF00069.20 EIE87527.1 - 3e-61 206.8 0.0 4e-61 206.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE87527.1 - 1e-29 103.4 0.0 1.4e-29 103.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE87527.1 - 1.9e-07 30.3 0.0 7.2e-07 28.4 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EIE87527.1 - 0.023 13.7 0.1 0.038 13.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIE87527.1 - 0.058 13.1 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.17 EIE87527.1 - 0.24 10.6 2.0 0.29 10.4 0.1 1.8 2 0 0 2 2 2 0 RIO1 family PWI PF01480.12 EIE87529.1 - 1.2e-10 41.3 1.0 1.2e-10 41.3 0.7 2.0 2 0 0 2 2 2 1 PWI domain RRM_1 PF00076.17 EIE87529.1 - 9.9e-08 31.5 0.0 2.2e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE87529.1 - 0.023 14.6 0.0 0.08 12.9 0.0 1.9 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) ADH_N PF08240.7 EIE87530.1 - 1.5e-24 85.8 4.3 2.6e-24 85.0 3.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIE87530.1 - 1.7e-19 69.6 0.0 2.4e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EIE87530.1 - 0.00071 18.7 0.0 0.0012 18.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GP41 PF00517.12 EIE87530.1 - 0.071 12.6 2.7 0.13 11.7 1.8 1.3 1 0 0 1 1 1 0 Retroviral envelope protein Mt_ATP-synt_B PF05405.9 EIE87531.1 - 3.4e-45 153.4 6.2 5e-45 152.8 4.3 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Hepatitis_core PF00906.15 EIE87531.1 - 0.03 13.9 0.3 0.05 13.2 0.2 1.3 1 0 0 1 1 1 0 Hepatitis core antigen DivIC PF04977.10 EIE87531.1 - 0.04 13.3 0.5 0.04 13.3 0.3 2.3 1 1 1 2 2 2 0 Septum formation initiator DUF4157 PF13699.1 EIE87531.1 - 0.22 11.7 0.2 0.22 11.7 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4157) DivIC PF04977.10 EIE87532.1 - 0.0021 17.4 2.0 0.0057 16.1 1.4 1.6 1 0 0 1 1 1 1 Septum formation initiator Lebercilin PF15619.1 EIE87532.1 - 0.012 15.0 2.6 0.012 15.0 1.8 1.5 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Herpes_BLRF2 PF05812.7 EIE87532.1 - 0.013 15.2 0.2 0.025 14.4 0.1 1.4 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein SlyX PF04102.7 EIE87532.1 - 0.068 13.5 0.8 0.16 12.3 0.6 1.7 1 0 0 1 1 1 0 SlyX HALZ PF02183.13 EIE87532.1 - 0.14 11.9 0.1 0.41 10.3 0.1 1.8 1 0 0 1 1 1 0 Homeobox associated leucine zipper GOLGA2L5 PF15070.1 EIE87532.1 - 0.31 9.4 1.3 0.42 9.0 0.9 1.1 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 Cep57_CLD_2 PF14197.1 EIE87532.1 - 0.56 10.1 4.8 1 9.3 1.7 2.2 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Gag_spuma PF03276.9 EIE87532.1 - 0.68 8.1 8.6 0.89 7.8 5.9 1.1 1 0 0 1 1 1 0 Spumavirus gag protein Lactamase_B_2 PF12706.2 EIE87537.1 - 1.3e-25 90.0 0.0 3.5e-25 88.6 0.0 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EIE87537.1 - 8.2e-10 38.6 0.0 2.8e-09 36.9 0.0 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.1 EIE87537.1 - 0.001 18.5 0.0 0.003 16.9 0.0 1.8 1 0 0 1 1 1 1 tRNase Z endonuclease Reticulon PF02453.12 EIE87538.1 - 1.1e-15 57.7 7.3 1.9e-15 56.8 4.1 1.8 1 1 1 2 2 2 1 Reticulon SAYSvFN PF10260.4 EIE87538.1 - 0.12 12.1 1.8 0.36 10.6 1.3 1.8 1 0 0 1 1 1 0 Uncharacterized conserved domain (SAYSvFN) COPI_assoc PF08507.5 EIE87538.1 - 0.13 11.9 3.8 0.2 11.3 0.4 2.1 2 0 0 2 2 2 0 COPI associated protein Methyltransf_25 PF13649.1 EIE87540.1 - 3.8e-11 43.2 0.0 1.9e-10 41.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIE87540.1 - 5.3e-10 39.6 0.0 1.4e-08 35.1 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIE87540.1 - 3.2e-08 33.9 0.0 1.5e-07 31.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIE87540.1 - 1.6e-07 31.0 0.0 2.7e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIE87540.1 - 1.1e-06 28.5 0.0 1.7e-06 27.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIE87540.1 - 6.8e-05 23.4 0.0 0.00013 22.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIE87540.1 - 0.0015 18.5 0.0 0.011 15.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 EIE87540.1 - 0.012 15.0 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) Ubie_methyltran PF01209.13 EIE87540.1 - 0.02 14.0 0.0 0.45 9.5 0.0 2.0 1 1 1 2 2 2 0 ubiE/COQ5 methyltransferase family Pox_MCEL PF03291.11 EIE87540.1 - 0.037 12.8 0.0 0.096 11.5 0.0 1.7 1 1 0 1 1 1 0 mRNA capping enzyme CheR PF01739.13 EIE87540.1 - 0.07 12.4 0.0 0.25 10.6 0.0 1.8 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain UCH_1 PF13423.1 EIE87541.1 - 4.6e-43 147.7 0.0 6.7e-33 114.3 0.6 2.2 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 EIE87541.1 - 3.8e-25 89.0 0.0 7.5e-25 88.1 0.0 1.5 1 0 0 1 1 1 1 Exonuclease UCH PF00443.24 EIE87541.1 - 2.4e-09 36.6 0.0 1.8e-08 33.8 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ribosomal_L39 PF00832.15 EIE87542.1 - 3.1e-19 68.1 12.5 3.5e-19 67.9 8.7 1.0 1 0 0 1 1 1 1 Ribosomal L39 protein Atg8 PF02991.11 EIE87543.1 - 2.9e-52 175.0 0.2 3.3e-52 174.7 0.1 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 EIE87543.1 - 1.1e-07 31.9 0.0 1.3e-07 31.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 F-box-like PF12937.2 EIE87544.1 - 6.2e-10 38.6 1.8 5.4e-09 35.6 0.2 2.6 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 EIE87544.1 - 7.1e-07 28.7 2.8 0.16 11.6 0.1 4.5 4 1 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EIE87544.1 - 0.0017 18.2 0.6 7.9 6.8 0.1 4.0 5 0 0 5 5 5 2 Leucine Rich repeat LRR_8 PF13855.1 EIE87544.1 - 0.0017 18.0 5.1 3.7 7.3 0.1 4.7 2 1 4 6 6 6 4 Leucine rich repeat LRR_1 PF00560.28 EIE87544.1 - 0.016 15.1 5.0 8.9 6.7 0.0 4.7 4 1 0 4 4 4 0 Leucine Rich Repeat LRR_7 PF13504.1 EIE87544.1 - 0.055 13.6 2.8 16 6.2 0.1 5.2 5 1 1 6 6 6 0 Leucine rich repeat F-box PF00646.28 EIE87544.1 - 0.06 13.0 1.8 0.17 11.5 0.1 2.6 2 0 0 2 2 2 0 F-box domain Pkinase PF00069.20 EIE87545.1 - 3.9e-25 88.4 0.0 5.6e-25 87.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE87545.1 - 6.4e-07 28.7 0.0 1.1e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase YrbL-PhoP_reg PF10707.4 EIE87545.1 - 0.0019 17.5 0.5 0.0055 16.0 0.0 1.9 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL APH PF01636.18 EIE87545.1 - 0.04 13.6 0.0 0.072 12.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pex14_N PF04695.8 EIE87545.1 - 0.34 10.9 4.7 0.58 10.2 3.3 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Epimerase_Csub PF13950.1 EIE87546.1 - 2.7e-28 97.7 0.5 4.1e-28 97.1 0.3 1.3 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit Epimerase PF01370.16 EIE87546.1 - 2.4e-27 95.8 0.0 3.1e-27 95.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EIE87546.1 - 4.3e-05 22.3 0.0 0.0015 17.2 0.0 2.1 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EIE87546.1 - 0.00034 19.6 0.0 0.00041 19.3 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EIE87546.1 - 0.0082 16.1 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 EIE87546.1 - 0.079 11.8 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Peptidase_C14 PF00656.17 EIE87547.1 - 2e-70 237.3 0.1 2.6e-70 236.9 0.1 1.1 1 0 0 1 1 1 1 Caspase domain Peptidase_S8 PF00082.17 EIE87548.1 - 1.2e-50 172.2 0.0 3.1e-50 170.9 0.0 1.6 1 1 0 1 1 1 1 Subtilase family PA PF02225.17 EIE87548.1 - 2.1e-18 65.8 0.1 1.2e-17 63.4 0.0 2.2 2 0 0 2 2 2 1 PA domain Fungal_trans PF04082.13 EIE87551.1 - 3e-07 29.5 0.7 5.2e-07 28.8 0.2 1.6 1 1 1 2 2 2 1 Fungal specific transcription factor domain Stc1 PF12898.2 EIE87552.1 - 1.6e-06 28.0 4.5 2e-06 27.7 3.1 1.1 1 0 0 1 1 1 1 Stc1 domain Jiv90 PF14901.1 EIE87552.1 - 0.13 12.2 1.5 0.14 12.1 1.1 1.1 1 0 0 1 1 1 0 Cleavage inducing molecular chaperone PhyH PF05721.8 EIE87553.1 - 6.3e-14 52.5 0.1 9e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_3 PF13640.1 EIE87553.1 - 0.00058 20.3 0.1 0.001 19.5 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GDE_N PF12439.3 EIE87553.1 - 0.069 12.3 0.1 0.1 11.8 0.1 1.2 1 0 0 1 1 1 0 Glycogen debranching enzyme N terminal Methyltransf_3 PF01596.12 EIE87554.1 - 1e-38 132.4 0.0 1.3e-38 132.1 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 EIE87554.1 - 2.4e-14 54.0 0.0 6.6e-14 52.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIE87554.1 - 1.6e-05 25.4 0.0 2.9e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIE87554.1 - 0.00025 21.0 0.0 0.00043 20.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EIE87554.1 - 0.01 15.4 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cons_hypoth95 PF03602.10 EIE87554.1 - 0.098 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 BUD22 PF09073.5 EIE87555.1 - 8.4e-18 64.6 66.3 9.3e-07 28.2 8.8 3.1 1 1 2 3 3 3 3 BUD22 Myb_DNA-binding PF00249.26 EIE87556.1 - 3.6e-45 151.7 18.1 8.5e-13 48.1 0.2 5.3 5 0 0 5 5 5 4 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EIE87556.1 - 3.9e-35 119.7 14.1 4.7e-13 49.0 0.1 6.2 3 3 4 7 7 7 5 Myb-like DNA-binding domain CPSase_L_D3 PF02787.14 EIE87556.1 - 0.058 13.1 4.1 0.057 13.1 1.1 2.2 2 0 0 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain Sugar_tr PF00083.19 EIE87557.1 - 2.4e-39 135.1 3.3 7.6e-21 74.1 0.0 3.0 2 1 1 3 3 3 3 Sugar (and other) transporter MFS_1 PF07690.11 EIE87557.1 - 4.7e-06 25.5 7.0 8.3e-05 21.4 1.6 2.9 3 0 0 3 3 3 2 Major Facilitator Superfamily MFS_3 PF05977.8 EIE87557.1 - 0.00023 19.4 3.4 0.0041 15.3 0.7 2.2 1 1 1 2 2 2 2 Transmembrane secretion effector Ribosomal_L7Ae PF01248.21 EIE87558.1 - 1.7e-05 24.2 0.0 2.6e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family F-box-like PF12937.2 EIE87559.1 - 1.3e-06 27.9 0.0 4.7e-06 26.2 0.0 2.0 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EIE87559.1 - 0.00076 19.0 0.5 0.5 10.0 0.1 2.8 2 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EIE87559.1 - 0.0019 17.9 2.3 1.7 8.4 0.4 3.5 3 1 0 3 3 3 2 Leucine rich repeat LRR_7 PF13504.1 EIE87559.1 - 0.014 15.4 0.7 44 4.9 0.0 4.6 4 2 0 4 4 4 0 Leucine rich repeat LRR_6 PF13516.1 EIE87559.1 - 0.02 14.9 0.4 1.2e+02 3.2 0.0 4.4 4 0 0 4 4 4 0 Leucine Rich repeat SPA PF08616.5 EIE87560.1 - 4.1e-37 126.3 0.0 1e-36 125.0 0.0 1.7 1 0 0 1 1 1 1 Stabilization of polarity axis Afi1 PF07792.7 EIE87560.1 - 3.6e-32 111.3 1.3 3.6e-29 101.6 0.2 2.7 2 1 0 2 2 2 1 Docking domain of Afi1 for Arf3 in vesicle trafficking Avl9 PF09794.4 EIE87560.1 - 4.4e-10 38.5 0.3 0.0009 17.8 0.0 4.1 3 1 1 4 4 4 2 Transport protein Avl9 DUF2347 PF09804.4 EIE87560.1 - 5.5e-09 35.6 0.0 0.0029 16.9 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2347) Rep_fac_C PF08542.6 EIE87561.1 - 7e-11 41.9 0.4 1.7e-10 40.6 0.3 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EIE87561.1 - 2.3e-09 37.0 0.1 4.9e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 EIE87561.1 - 2e-06 28.0 0.5 6.2e-06 26.4 0.0 1.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta PF06144.8 EIE87561.1 - 0.0004 19.9 0.0 0.00076 19.0 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_22 PF13401.1 EIE87561.1 - 0.093 12.8 0.0 0.3 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain Lactamase_B_2 PF12706.2 EIE87562.1 - 1.8e-24 86.3 0.7 2.8e-24 85.7 0.5 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EIE87562.1 - 1.8e-06 27.7 0.1 4.4e-06 26.4 0.0 1.7 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EIE87562.1 - 0.0058 16.3 0.6 0.019 14.6 0.4 1.8 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Ras PF00071.17 EIE87563.1 - 8.9e-65 217.0 0.5 1.1e-64 216.7 0.3 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIE87563.1 - 1.2e-21 77.4 0.0 2.1e-21 76.6 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIE87563.1 - 1.1e-17 63.7 0.1 1.4e-17 63.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EIE87563.1 - 2.4e-07 30.1 0.0 3.3e-07 29.6 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EIE87563.1 - 8.8e-07 28.5 0.3 1.8e-06 27.5 0.2 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EIE87563.1 - 3.4e-05 23.7 0.0 6e-05 22.9 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EIE87563.1 - 4.8e-05 22.6 0.4 7.4e-05 22.0 0.0 1.4 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 EIE87563.1 - 0.00052 19.3 0.1 0.0017 17.6 0.1 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_22 PF13401.1 EIE87563.1 - 0.00082 19.5 0.0 0.0012 18.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain Septin PF00735.13 EIE87563.1 - 0.0021 17.1 0.1 0.18 10.7 0.0 2.2 2 0 0 2 2 2 1 Septin AAA PF00004.24 EIE87563.1 - 0.0052 16.9 0.1 0.072 13.2 0.0 2.1 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.12 EIE87563.1 - 0.01 15.4 0.2 0.028 13.9 0.0 1.6 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein DUF258 PF03193.11 EIE87563.1 - 0.016 14.4 0.2 0.056 12.6 0.0 1.9 2 1 0 2 2 2 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 EIE87563.1 - 0.019 14.9 0.3 0.042 13.8 0.1 1.9 1 1 1 2 2 2 0 AAA ATPase domain AAA_29 PF13555.1 EIE87563.1 - 0.038 13.5 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 EIE87563.1 - 0.042 13.5 0.0 0.075 12.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 EIE87563.1 - 0.056 13.7 0.1 0.12 12.7 0.1 1.8 1 1 0 1 1 1 0 ABC transporter PduV-EutP PF10662.4 EIE87563.1 - 0.069 12.6 0.1 1.1 8.7 0.0 2.2 1 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.1 EIE87563.1 - 0.1 12.1 1.2 1.3 8.5 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EIE87563.1 - 0.11 12.3 0.1 0.42 10.5 0.1 1.9 1 1 0 1 1 1 0 AAA domain PH_9 PF15410.1 EIE87564.1 - 5.7e-05 23.2 0.1 0.00012 22.1 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EIE87564.1 - 0.00043 20.4 0.2 0.00077 19.6 0.1 1.4 1 0 0 1 1 1 1 PH domain 7tm_3 PF00003.17 EIE87564.1 - 0.017 14.5 3.5 0.024 14.0 2.4 1.2 1 0 0 1 1 1 0 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.23 EIE87565.1 - 3.6e-12 45.7 4.6 3.4e-08 32.6 1.2 2.0 1 1 1 2 2 2 2 Receptor family ligand binding region Peripla_BP_6 PF13458.1 EIE87565.1 - 0.00018 20.9 0.7 0.00039 19.8 0.2 1.6 1 1 1 2 2 2 1 Periplasmic binding protein SAM_2 PF07647.12 EIE87565.1 - 0.0014 18.4 0.1 0.0029 17.4 0.0 1.5 1 1 0 1 1 1 1 SAM domain (Sterile alpha motif) Ank PF00023.25 EIE87570.1 - 3.1e-33 111.9 0.4 2.5e-07 30.1 0.1 4.7 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 EIE87570.1 - 9e-31 105.7 5.7 1.5e-13 50.8 0.3 4.5 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.2 EIE87570.1 - 1.7e-30 105.1 2.1 5.2e-16 58.7 0.3 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EIE87570.1 - 5.8e-25 86.7 1.9 2.1e-10 40.4 0.1 4.7 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIE87570.1 - 6.7e-24 81.5 3.0 2e-06 27.4 0.1 4.8 4 0 0 4 4 4 4 Ankyrin repeat FYVE PF01363.16 EIE87570.1 - 2.1e-19 69.1 5.3 4e-19 68.2 3.6 1.4 1 0 0 1 1 1 1 FYVE zinc finger MIT PF04212.13 EIE87570.1 - 0.00032 20.5 1.0 0.00079 19.2 0.7 1.7 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain FYVE_2 PF02318.11 EIE87570.1 - 0.019 14.8 3.3 0.019 14.8 2.3 2.0 2 0 0 2 2 2 0 FYVE-type zinc finger DIL PF01843.14 EIE87571.1 - 8.7e-22 76.9 4.4 2.1e-21 75.7 3.1 1.7 1 0 0 1 1 1 1 DIL domain Ank_2 PF12796.2 EIE87571.1 - 3.5e-19 68.9 0.0 7.1e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EIE87571.1 - 2.6e-16 58.4 0.1 3.4e-07 29.7 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 EIE87571.1 - 1.3e-12 47.4 0.0 3.8e-09 36.4 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EIE87571.1 - 2e-12 47.2 0.1 4.9e-05 23.7 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIE87571.1 - 6.6e-12 44.4 0.1 9.7e-05 22.2 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat Cas_CXXC_CXXC PF09706.5 EIE87572.1 - 0.037 14.2 1.9 0.053 13.6 1.3 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_CXXC_CXXC) RabGAP-TBC PF00566.13 EIE87573.1 - 4.4e-16 58.9 2.9 7.1e-16 58.3 1.7 1.6 1 1 1 2 2 2 1 Rab-GTPase-TBC domain Arrestin_N PF00339.24 EIE87574.1 - 9.5e-12 44.9 0.0 4.2e-11 42.8 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EIE87574.1 - 1.6e-06 28.2 1.1 3.3e-06 27.2 0.8 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.2 EIE87574.1 - 0.037 13.5 0.0 0.075 12.5 0.0 1.5 1 0 0 1 1 1 0 Arrestin_N terminal like UDPGP PF01704.13 EIE87575.1 - 2.3e-58 197.6 0.0 3.6e-58 197.0 0.0 1.2 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 EIE87575.1 - 0.088 12.8 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 MobA-like NTP transferase domain Peptidase_S8 PF00082.17 EIE87576.1 - 1.8e-47 161.8 0.0 3.5e-47 160.8 0.0 1.5 1 1 0 1 1 1 1 Subtilase family PA PF02225.17 EIE87576.1 - 1.2e-09 37.8 0.0 5e-09 35.7 0.0 2.1 3 0 0 3 3 3 1 PA domain DUF1034 PF06280.7 EIE87576.1 - 2.2e-08 34.4 0.6 1.4e-07 31.9 0.4 2.5 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) DUF2201 PF09967.4 EIE87577.1 - 0.11 12.5 0.1 0.13 12.3 0.1 1.2 1 0 0 1 1 1 0 VWA-like domain (DUF2201) AhpC-TSA PF00578.16 EIE87578.1 - 2.2e-26 91.9 0.0 3.3e-26 91.4 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.4 EIE87578.1 - 2.7e-15 55.7 0.1 5.2e-15 54.8 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.5 EIE87578.1 - 1.9e-08 33.9 0.0 2.6e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Redoxin DUF3647 PF12363.3 EIE87581.1 - 0.01 15.9 0.9 0.013 15.6 0.6 1.2 1 0 0 1 1 1 0 Phage protein Rapamycin_bind PF08771.6 EIE87581.1 - 0.12 12.4 0.2 0.13 12.3 0.1 1.1 1 0 0 1 1 1 0 Rapamycin binding domain SSPI PF14098.1 EIE87581.1 - 0.26 11.2 2.4 1.2 9.1 0.2 2.0 2 0 0 2 2 2 0 Small, acid-soluble spore protein I DUF4403 PF14356.1 EIE87585.1 - 0.067 11.4 0.0 0.099 10.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4403) CRM1_C PF08767.6 EIE87588.1 - 2.9e-05 23.1 0.9 2.9e-05 23.1 0.6 2.8 2 0 0 2 2 2 1 CRM1 C terminal Myb_DNA-bind_6 PF13921.1 EIE87589.1 - 0.00014 21.8 4.3 0.00022 21.2 0.7 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EIE87589.1 - 0.002 18.1 0.5 0.0039 17.2 0.3 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain MUG2_C PF08593.5 EIE87589.1 - 0.11 12.7 0.1 0.95 9.7 0.0 2.3 2 0 0 2 2 2 0 Meiotically up-regulated glycoproteins C-terminal Kinesin PF00225.18 EIE87590.1 - 1.5e-111 372.3 0.9 1.5e-111 372.3 0.6 3.2 3 0 0 3 3 3 1 Kinesin motor domain Dynactin PF12455.3 EIE87590.1 - 3.5e-65 219.6 8.4 3.5e-65 219.6 5.9 4.9 4 1 0 5 5 5 1 Dynein associated protein CAP_GLY PF01302.20 EIE87590.1 - 2.6e-24 84.6 1.0 4.5e-24 83.9 0.7 1.4 1 0 0 1 1 1 1 CAP-Gly domain HIG_1_N PF04588.8 EIE87591.1 - 2.1e-19 68.9 2.3 2.1e-19 68.9 1.6 1.4 2 0 0 2 2 2 1 Hypoxia induced protein conserved region FtsJ PF01728.14 EIE87592.1 - 1.8e-05 24.7 0.0 2.9e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase G-patch_2 PF12656.2 EIE87594.1 - 2.7e-26 91.1 0.0 1.5e-25 88.8 0.0 2.4 1 0 0 1 1 1 1 DExH-box splicing factor binding site G-patch PF01585.18 EIE87594.1 - 8.3e-05 22.2 0.1 0.00019 21.1 0.0 1.7 1 0 0 1 1 1 1 G-patch domain Sulfate_tra_GLY PF13792.1 EIE87595.1 - 3e-05 23.5 0.1 0.00017 21.1 0.0 2.0 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif Ribosomal_L44 PF00935.14 EIE87598.1 - 7.7e-36 121.9 10.1 1.1e-35 121.5 7.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L44 Ribosomal_L33 PF00471.15 EIE87598.1 - 6.2 7.1 9.2 3.4 7.9 1.2 2.7 2 1 0 2 2 2 0 Ribosomal protein L33 RNA_pol_Rpb2_1 PF04563.10 EIE87600.1 - 2e-29 101.9 0.0 2.3e-29 101.8 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase beta subunit SRP72 PF08492.7 EIE87601.1 - 1.7e-14 53.9 7.6 1.7e-14 53.9 5.3 2.8 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_14 PF13428.1 EIE87601.1 - 5.2e-12 45.2 14.3 0.47 11.2 0.3 8.6 5 3 4 9 9 9 3 Tetratricopeptide repeat TPR_2 PF07719.12 EIE87601.1 - 1.4e-10 40.2 9.6 0.22 11.5 0.1 7.0 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.1 EIE87601.1 - 2e-10 41.0 18.7 0.021 15.4 2.6 6.1 5 2 1 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.1 EIE87601.1 - 2.7e-08 33.3 23.2 0.012 15.2 0.2 6.5 3 2 3 6 6 6 4 TPR repeat Apc3 PF12895.2 EIE87601.1 - 3.1e-08 33.6 23.1 2.5e-05 24.3 0.6 5.6 2 2 2 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 EIE87601.1 - 6.8e-08 32.7 37.8 0.011 16.0 0.1 6.9 6 2 1 7 7 7 4 Tetratricopeptide repeat TPR_6 PF13174.1 EIE87601.1 - 1.1e-07 31.8 24.3 0.38 11.3 0.1 8.3 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_1 PF00515.23 EIE87601.1 - 5e-07 29.0 11.9 0.55 9.9 0.0 6.9 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.1 EIE87601.1 - 6.3e-07 29.2 24.2 1.8e-05 24.5 1.8 5.8 3 2 4 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.1 EIE87601.1 - 6.9e-05 22.3 10.8 0.55 10.1 0.0 5.5 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 EIE87601.1 - 0.0009 18.8 16.8 5 7.1 0.1 6.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_4 PF07721.9 EIE87601.1 - 0.0014 18.8 0.2 61 4.4 0.0 5.1 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_17 PF13431.1 EIE87601.1 - 0.0029 17.6 6.8 3.4 8.0 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.1 EIE87601.1 - 0.0054 16.6 2.7 3.7 7.5 0.0 5.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.1 EIE87601.1 - 0.0057 16.4 14.8 9 6.2 0.1 6.6 5 3 2 7 7 7 0 Tetratricopeptide repeat BTAD PF03704.12 EIE87601.1 - 0.032 14.5 0.2 0.032 14.5 0.1 3.9 3 1 1 4 4 4 0 Bacterial transcriptional activator domain DUF3698 PF12479.3 EIE87601.1 - 0.19 11.8 2.1 0.29 11.2 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3698) TPR_3 PF07720.7 EIE87601.1 - 0.38 10.6 0.0 0.38 10.6 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_20 PF14561.1 EIE87601.1 - 0.44 10.6 19.3 2.2 8.4 2.4 4.8 4 2 0 4 4 4 0 Tetratricopeptide repeat MFS_1 PF07690.11 EIE87602.1 - 2.3e-25 89.0 20.2 1.1e-10 40.8 1.0 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily LacY_symp PF01306.14 EIE87602.1 - 1.3e-10 40.4 7.6 1.3e-10 40.4 5.3 2.0 2 0 0 2 2 2 1 LacY proton/sugar symporter MFS_1_like PF12832.2 EIE87602.1 - 3.3e-06 26.8 2.4 1.3e-05 24.8 1.7 2.1 1 0 0 1 1 1 1 MFS_1 like family HSP20 PF00011.16 EIE87602.1 - 0.08 12.8 0.7 0.18 11.6 0.5 1.5 1 0 0 1 1 1 0 Hsp20/alpha crystallin family Nuc_H_symport PF03825.11 EIE87602.1 - 0.68 8.6 27.6 0.0076 15.0 7.2 2.9 2 1 0 2 2 2 0 Nucleoside H+ symporter DUF2244 PF10003.4 EIE87602.1 - 1.7 8.0 0.0 1.7 8.0 0.0 3.7 4 1 1 5 5 5 0 Integral membrane protein (DUF2244) Na_Ca_ex PF01699.19 EIE87603.1 - 4.6e-45 152.6 38.5 1.7e-23 82.8 10.1 2.5 3 0 0 3 3 3 2 Sodium/calcium exchanger protein DUF3995 PF13160.1 EIE87603.1 - 0.22 11.5 0.1 0.22 11.5 0.0 3.2 3 2 1 5 5 5 0 Protein of unknown function (DUF3995) RNA_pol_Rpb2_6 PF00562.23 EIE87604.1 - 7.5e-120 400.2 0.0 1.4e-119 399.2 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EIE87604.1 - 6.5e-60 201.5 1.2 7.9e-60 201.2 0.4 1.5 2 0 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EIE87604.1 - 9.4e-34 116.4 2.2 2.5e-33 115.1 1.5 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EIE87604.1 - 4.1e-29 100.6 2.8 6.9e-29 99.9 0.1 2.9 3 0 0 3 3 3 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 EIE87604.1 - 3.2e-22 78.1 3.2 8.7e-22 76.7 1.7 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 EIE87604.1 - 3.6e-22 77.8 0.0 1.3e-21 76.0 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 EIE87604.1 - 2.1e-13 49.9 0.1 5.1e-13 48.7 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 NAD_binding_10 PF13460.1 EIE87605.1 - 4.6e-17 62.6 0.0 6.6e-17 62.1 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EIE87605.1 - 4.7e-15 55.4 0.0 3e-09 36.4 0.0 2.1 2 0 0 2 2 2 2 NmrA-like family TrkA_N PF02254.13 EIE87605.1 - 5.3e-05 23.1 0.0 0.00012 22.1 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain Epimerase PF01370.16 EIE87605.1 - 0.00021 20.7 0.0 0.00037 20.0 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_2 PF03446.10 EIE87605.1 - 0.00074 19.3 0.0 0.0012 18.6 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Polysacc_synt_2 PF02719.10 EIE87605.1 - 0.0038 16.1 0.0 2.1 7.1 0.0 2.2 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein F420_oxidored PF03807.12 EIE87605.1 - 0.0046 17.3 0.0 0.02 15.3 0.0 2.1 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.14 EIE87605.1 - 0.016 13.9 0.0 0.05 12.3 0.0 1.8 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_7 PF13241.1 EIE87605.1 - 0.017 15.3 0.0 0.043 14.0 0.0 1.9 1 1 0 1 1 1 0 Putative NAD(P)-binding adh_short PF00106.20 EIE87605.1 - 0.044 13.7 0.0 0.097 12.5 0.0 1.6 1 0 0 1 1 1 0 short chain dehydrogenase DUF4050 PF13259.1 EIE87606.1 - 2.4e-13 50.0 0.1 3e-13 49.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4050) PAPS_reduct PF01507.14 EIE87607.1 - 5.2e-14 52.4 0.0 7.5e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family tRNA-synt_2b PF00587.20 EIE87608.1 - 2.6e-29 102.0 0.0 3.6e-29 101.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EIE87608.1 - 7.6e-06 25.9 1.1 7.6e-06 25.9 0.8 1.7 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain ERO1 PF04137.10 EIE87610.1 - 4.1e-119 397.7 1.3 5.2e-119 397.4 0.9 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) DUF1823 PF08853.6 EIE87612.1 - 0.033 13.9 0.0 0.043 13.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1823) Glyco_transf_54 PF04666.8 EIE87612.1 - 0.11 11.2 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region PADR1 PF08063.7 EIE87612.1 - 0.2 11.0 0.9 0.46 9.9 0.1 1.8 1 1 1 2 2 2 0 PADR1 (NUC008) domain Ank PF00023.25 EIE87614.1 - 1.9e-06 27.4 1.9 6.1e-06 25.7 0.0 2.6 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.1 EIE87614.1 - 1.3e-05 25.5 0.7 0.0029 18.0 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EIE87614.1 - 3.3e-05 23.9 0.0 0.0001 22.4 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 EIE87614.1 - 0.00058 20.1 0.1 0.0013 19.0 0.1 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EIE87614.1 - 0.0024 17.9 0.0 0.01 15.9 0.0 2.1 1 0 0 1 1 1 1 Ankyrin repeat Bromodomain PF00439.20 EIE87615.1 - 1.3e-17 63.4 0.0 3.9e-17 61.9 0.0 1.8 1 0 0 1 1 1 1 Bromodomain Pkinase PF00069.20 EIE87615.1 - 5.4e-14 51.9 0.0 5.8e-06 25.6 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIE87615.1 - 1.2e-05 24.4 0.1 0.024 13.7 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 EIE87615.1 - 0.012 14.6 0.0 0.034 13.2 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PH_9 PF15410.1 EIE87619.1 - 4.4e-23 81.7 0.0 1.1e-22 80.3 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EIE87619.1 - 6.4e-05 23.0 0.2 0.00033 20.8 0.0 2.2 2 0 0 2 2 2 1 PH domain adh_short PF00106.20 EIE87620.1 - 2.1e-22 79.8 0.2 1.6e-20 73.6 0.2 2.3 1 1 0 1 1 1 1 short chain dehydrogenase H2TH PF06831.9 EIE87620.1 - 1.2e-21 76.2 0.2 5e-21 74.2 0.0 2.1 2 0 0 2 2 2 1 Formamidopyrimidine-DNA glycosylase H2TH domain KR PF08659.5 EIE87620.1 - 1.1e-10 41.4 2.1 4.7e-09 36.1 0.3 2.7 2 1 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 EIE87620.1 - 2.7e-05 24.0 1.0 0.00013 21.8 0.0 2.3 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EIE87620.1 - 0.00014 21.9 0.0 0.00037 20.5 0.0 1.8 1 0 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EIE87620.1 - 0.006 16.3 0.0 0.016 14.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF2393 PF09624.5 EIE87620.1 - 0.03 13.8 0.8 0.03 13.8 0.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2393) DUF948 PF06103.6 EIE87622.1 - 0.0083 15.9 0.9 0.0083 15.9 0.6 4.7 4 1 1 5 5 5 1 Bacterial protein of unknown function (DUF948) ABC_tran PF00005.22 EIE87623.1 - 6.4e-11 42.6 0.0 8.8e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter Methyltransf_PK PF05891.7 EIE87624.1 - 2.4e-85 285.2 0.0 2.7e-85 285.1 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.1 EIE87624.1 - 4.4e-09 36.6 0.1 6.7e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIE87624.1 - 2.8e-08 33.6 0.0 4e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIE87624.1 - 6.4e-08 32.9 0.0 9.5e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIE87624.1 - 1.2e-07 32.1 0.0 1.7e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIE87624.1 - 7.8e-07 29.6 0.0 1.1e-06 29.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIE87624.1 - 0.0016 18.0 0.0 0.002 17.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EIE87624.1 - 0.0019 17.5 0.0 0.0034 16.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.13 EIE87624.1 - 0.013 14.7 0.0 0.018 14.2 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase JAB PF01398.16 EIE87625.1 - 4.3e-15 55.4 0.0 5e-15 55.2 0.0 1.1 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 EIE87625.1 - 0.00026 20.5 0.0 0.00036 20.0 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain zf-C2H2 PF00096.21 EIE87627.1 - 1.4e-10 40.8 10.7 9.8e-06 25.6 1.5 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIE87627.1 - 2.3e-09 37.0 9.7 4.2e-08 33.0 0.1 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EIE87627.1 - 2.6e-09 36.7 7.1 9.7e-05 22.4 1.4 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EIE87627.1 - 7.4e-05 22.7 3.2 0.04 14.0 0.1 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EIE87627.1 - 0.012 15.7 5.9 0.12 12.5 0.2 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.1 EIE87627.1 - 0.15 12.3 1.9 0.39 11.0 0.3 2.5 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-met PF12874.2 EIE87627.1 - 0.25 11.6 3.6 0.99 9.7 0.4 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DUF2321 PF10083.4 EIE87627.1 - 0.35 10.3 2.4 0.26 10.7 0.3 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) Molybdopterin PF00384.17 EIE87628.1 - 1.2e-69 235.0 0.0 8.1e-69 232.4 0.0 1.9 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.1 EIE87628.1 - 7.8e-19 67.2 0.2 1.2e-17 63.5 0.1 2.5 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.4 EIE87628.1 - 8.5e-18 63.3 0.1 2e-17 62.1 0.1 1.7 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region DUF1982 PF09326.6 EIE87628.1 - 1.4e-14 53.9 0.1 3.6e-14 52.6 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1982) Fer2 PF00111.22 EIE87628.1 - 5.1e-08 32.5 0.4 5.1e-08 32.5 0.2 1.8 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.17 EIE87628.1 - 0.0081 15.9 0.0 1.4 8.6 0.0 2.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain BRCA-2_OB3 PF09104.5 EIE87629.1 - 0.046 13.5 0.0 0.049 13.4 0.0 1.1 1 0 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 Nab2 PF11517.3 EIE87629.1 - 0.1 12.6 0.0 0.17 11.9 0.0 1.3 1 1 0 1 1 1 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) Metallophos PF00149.23 EIE87630.1 - 2e-31 108.9 0.1 3.5e-31 108.1 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Zds_C PF08632.5 EIE87631.1 - 2e-19 68.7 1.4 4.4e-19 67.6 1.0 1.5 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Cation_ATPase_C PF00689.16 EIE87632.1 - 3.4e-08 33.2 17.4 4.2e-08 32.9 12.1 1.1 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Integrin_b_cyt PF08725.6 EIE87632.1 - 0.018 14.4 0.3 0.03 13.6 0.2 1.3 1 0 0 1 1 1 0 Integrin beta cytoplasmic domain E1-E2_ATPase PF00122.15 EIE87633.1 - 0.3 10.1 0.5 1.5 7.7 0.0 2.0 2 0 0 2 2 2 0 E1-E2 ATPase DUF21 PF01595.15 EIE87634.1 - 2.7e-33 114.8 0.3 6.4e-33 113.5 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 EIE87634.1 - 2.6e-07 30.3 0.2 0.013 15.2 0.0 3.0 3 0 0 3 3 3 2 CBS domain BTB PF00651.26 EIE87634.1 - 2.2e-05 24.3 0.0 7.8e-05 22.6 0.0 1.9 1 0 0 1 1 1 1 BTB/POZ domain Dabb PF07876.7 EIE87635.1 - 4.2e-21 75.2 0.1 4.6e-21 75.0 0.1 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Chitin_synth_2 PF03142.10 EIE87636.1 - 5.9e-236 783.9 1.0 8.9e-236 783.3 0.7 1.2 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 EIE87636.1 - 6.1e-15 55.4 2.6 1.5e-14 54.1 1.8 1.7 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EIE87636.1 - 4.8e-13 49.4 0.0 1.1e-12 48.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EIE87636.1 - 5.9e-06 25.6 0.1 0.00027 20.2 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 21 Cyt-b5 PF00173.23 EIE87636.1 - 0.0034 17.1 0.0 0.0069 16.1 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glycos_transf_2 PF00535.21 EIE87636.1 - 0.0062 16.2 0.0 0.066 12.8 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 2 MEA1 PF06910.6 EIE87637.1 - 3.8e-05 23.4 2.0 5.8e-05 22.8 1.2 1.4 1 1 0 1 1 1 1 Male enhanced antigen 1 (MEA1) MTHFR PF02219.12 EIE87638.1 - 1.8e-116 388.2 0.0 2.4e-116 387.8 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Pkinase PF00069.20 EIE87639.1 - 4.3e-46 157.1 1.3 1.4e-45 155.5 0.0 2.5 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE87639.1 - 3.5e-16 59.0 0.0 3.8e-11 42.5 0.0 4.0 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIE87639.1 - 1.7e-05 24.6 0.0 0.011 15.5 0.0 2.7 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EIE87639.1 - 0.0096 14.9 0.0 0.023 13.6 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Gcd10p PF04189.8 EIE87639.1 - 0.019 14.0 5.0 0.033 13.3 3.4 1.4 1 0 0 1 1 1 0 Gcd10p family Kdo PF06293.9 EIE87639.1 - 0.044 12.8 0.0 0.1 11.6 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF190 PF02641.10 EIE87639.1 - 0.076 12.8 0.2 0.17 11.7 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized ACR, COG1993 Choline_kinase PF01633.15 EIE87639.1 - 0.12 11.9 2.7 0.39 10.2 0.0 2.4 2 0 0 2 2 2 0 Choline/ethanolamine kinase TauD PF02668.11 EIE87640.1 - 1e-22 81.0 0.0 1.2e-22 80.8 0.0 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family SH3_2 PF07653.12 EIE87640.1 - 0.11 11.9 0.1 23 4.5 0.0 2.6 3 0 0 3 3 3 0 Variant SH3 domain GCR1_C PF12550.3 EIE87641.1 - 5.1e-26 90.3 0.7 5.1e-25 87.1 0.2 2.6 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes MFS_1 PF07690.11 EIE87642.1 - 2.9e-21 75.6 25.1 2.9e-21 75.6 17.4 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily RNA_lig_T4_1 PF09511.5 EIE87643.1 - 2.2e-62 210.4 0.8 2.2e-62 210.4 0.5 1.7 1 1 1 2 2 2 1 RNA ligase Aromatic_hydrox PF11723.3 EIE87644.1 - 0.09 12.0 0.1 0.13 11.5 0.1 1.2 1 0 0 1 1 1 0 Homotrimeric ring hydroxylase Lactamase_B PF00753.22 EIE87646.1 - 3.5e-08 33.3 0.1 4.9e-08 32.8 0.1 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Radical_SAM PF04055.16 EIE87647.1 - 6.1e-13 49.2 0.1 8.9e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily C2 PF00168.25 EIE87648.1 - 2.3e-21 75.4 0.1 3e-21 75.0 0.1 1.1 1 0 0 1 1 1 1 C2 domain C2 PF00168.25 EIE87650.1 - 2.5e-20 72.0 0.1 3.3e-20 71.7 0.0 1.1 1 0 0 1 1 1 1 C2 domain Ecl1 PF12855.2 EIE87651.1 - 1.7e-07 30.3 5.3 3.3e-07 29.4 3.7 1.4 1 0 0 1 1 1 1 Life-span regulatory factor zf-MYND PF01753.13 EIE87651.1 - 0.0047 16.7 2.7 0.011 15.5 1.9 1.6 1 0 0 1 1 1 1 MYND finger GPI-anchored PF10342.4 EIE87652.1 - 0.00028 21.2 0.9 0.00028 21.2 0.6 2.6 2 2 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family TPP_enzyme_N PF02776.13 EIE87654.1 - 1.3e-28 99.6 0.0 2.4e-28 98.7 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EIE87654.1 - 5e-21 74.9 0.0 1e-20 73.8 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EIE87654.1 - 1.2e-17 63.8 0.0 2.7e-17 62.7 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain CO_dh PF02552.11 EIE87654.1 - 0.059 12.9 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit DUF3535 PF12054.3 EIE87655.1 - 3.3e-110 368.7 2.5 2.2e-108 362.7 0.3 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 EIE87655.1 - 9e-73 244.6 0.0 1.5e-72 243.9 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain HEAT PF02985.17 EIE87655.1 - 1.3e-14 52.9 9.6 0.11 12.6 0.1 10.0 10 0 0 10 10 10 3 HEAT repeat Helicase_C PF00271.26 EIE87655.1 - 3.6e-13 49.1 0.0 1.1e-12 47.5 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Vac14_Fab1_bd PF12755.2 EIE87655.1 - 9e-05 22.7 0.9 1.5 9.2 0.1 4.0 3 1 1 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.1 EIE87655.1 - 0.00019 21.6 2.1 0.038 14.2 0.1 4.8 5 1 1 6 6 6 1 HEAT repeats DUF1546 PF07571.8 EIE87655.1 - 0.00048 20.1 0.8 7 6.8 0.0 5.1 5 0 0 5 5 5 1 Protein of unknown function (DUF1546) HEAT_EZ PF13513.1 EIE87655.1 - 0.00061 20.1 13.5 5.3 7.6 0.0 7.3 7 0 0 7 7 7 1 HEAT-like repeat Ipi1_N PF12333.3 EIE87655.1 - 0.098 12.6 2.5 20 5.2 0.0 4.4 4 0 0 4 4 4 0 Rix1 complex component involved in 60S ribosome maturation Ribosomal_S10 PF00338.17 EIE87657.1 - 2e-29 101.3 0.0 3.3e-29 100.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e OPT PF03169.10 EIE87658.1 - 5.8e-139 464.3 18.9 6.5e-139 464.2 13.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Pap_E4 PF02711.9 EIE87658.1 - 0.043 14.6 0.6 0.079 13.7 0.4 1.4 1 0 0 1 1 1 0 E4 protein A1_Propeptide PF07966.7 EIE87658.1 - 0.17 11.7 1.4 0.44 10.4 1.0 1.7 1 0 0 1 1 1 0 A1 Propeptide 14-3-3 PF00244.15 EIE87660.1 - 3.9e-114 379.6 5.9 4.6e-114 379.3 4.1 1.0 1 0 0 1 1 1 1 14-3-3 protein Imm7 PF15588.1 EIE87660.1 - 0.044 13.8 0.2 0.35 10.9 0.0 2.2 2 0 0 2 2 2 0 Immunity protein 7 DUF327 PF03885.8 EIE87660.1 - 0.067 13.0 0.9 0.22 11.3 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF327) Gti1_Pac2 PF09729.4 EIE87661.1 - 1.1e-27 96.9 1.8 4.8e-14 52.5 0.1 3.1 1 1 2 3 3 3 3 Gti1/Pac2 family RTC PF01137.16 EIE87662.1 - 1.7e-66 223.2 0.0 2.1e-66 223.0 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 EIE87662.1 - 8.1e-20 70.7 0.6 8.4e-12 45.0 0.0 2.3 1 1 1 2 2 2 2 RNA 3'-terminal phosphate cyclase (RTC), insert domain LSM PF01423.17 EIE87663.1 - 5.6e-06 25.8 0.2 0.0008 18.9 0.1 2.2 1 1 0 1 1 1 1 LSM domain SMC_N PF02463.14 EIE87664.1 - 8.3e-58 195.2 26.5 4.9e-57 192.6 18.4 2.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EIE87664.1 - 5.4e-13 49.5 32.5 6.1e-10 39.5 3.2 4.2 3 1 0 3 3 3 2 AAA domain SMC_hinge PF06470.8 EIE87664.1 - 1.1e-11 44.7 0.0 7.1e-06 25.9 0.0 3.0 1 1 1 2 2 2 2 SMC proteins Flexible Hinge Domain AAA_29 PF13555.1 EIE87664.1 - 0.0047 16.4 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain MotA_activ PF09114.5 EIE87664.1 - 0.022 14.4 0.1 0.067 12.9 0.0 1.9 1 0 0 1 1 1 0 Transcription factor MotA, activation domain AAA_23 PF13476.1 EIE87664.1 - 1.6 9.0 133.0 11 6.3 55.0 7.2 2 2 0 2 2 2 0 AAA domain VTC PF09359.5 EIE87665.1 - 6.8e-70 235.2 0.2 1.4e-69 234.2 0.1 1.5 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 EIE87665.1 - 3.7e-24 85.9 15.9 3.1e-14 53.4 6.9 3.6 2 1 1 3 3 3 2 SPX domain DUF202 PF02656.10 EIE87665.1 - 5.5e-09 36.1 0.9 1.2e-08 35.0 0.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF202) ScpA_ScpB PF02616.9 EIE87665.1 - 0.007 15.9 0.9 0.007 15.9 0.6 1.7 2 0 0 2 2 2 1 ScpA/B protein DUF1664 PF07889.7 EIE87665.1 - 0.029 14.1 0.5 0.075 12.8 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) TRAPPC-Trs85 PF12739.2 EIE87666.1 - 4.6e-102 341.7 11.0 4.8e-102 341.6 4.6 2.6 2 1 0 2 2 2 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit SNAP PF14938.1 EIE87666.1 - 0.0073 15.4 2.4 0.39 9.8 0.2 2.2 2 0 0 2 2 2 2 Soluble NSF attachment protein, SNAP zf-MYND PF01753.13 EIE87667.1 - 5e-05 23.0 23.8 5e-05 23.0 16.5 2.6 3 1 0 3 3 3 1 MYND finger DUF2521 PF10730.4 EIE87668.1 - 0.011 15.5 0.1 0.014 15.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2521) Herpes_UL82_83 PF05784.6 EIE87668.1 - 0.013 14.3 0.1 0.016 14.0 0.0 1.0 1 0 0 1 1 1 0 Betaherpesvirus UL82/83 protein N terminus Dicty_CAR PF05462.6 EIE87668.1 - 0.048 12.5 0.1 0.054 12.3 0.1 1.0 1 0 0 1 1 1 0 Slime mold cyclic AMP receptor Tetrabrachion PF11401.3 EIE87668.1 - 0.093 12.5 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Tetrabrachion DUF971 PF06155.7 EIE87668.1 - 0.095 13.1 0.0 0.14 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF971) Na_H_Exchanger PF00999.16 EIE87669.1 - 2.3e-44 151.4 14.5 3.6e-44 150.8 10.1 1.3 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.1 EIE87669.1 - 0.013 15.4 1.8 0.15 12.0 0.1 2.7 2 0 0 2 2 2 0 YrhC-like protein bZIP_2 PF07716.10 EIE87670.1 - 1.7e-09 37.3 10.1 1.7e-09 37.3 7.0 2.2 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 EIE87670.1 - 3.7e-05 23.6 8.9 8e-05 22.5 6.2 1.6 1 0 0 1 1 1 1 bZIP transcription factor SR-25 PF10500.4 EIE87670.1 - 0.00076 19.0 10.1 0.001 18.6 7.0 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein XhlA PF10779.4 EIE87670.1 - 0.071 13.0 3.8 0.2 11.5 2.6 1.9 1 0 0 1 1 1 0 Haemolysin XhlA B3_4 PF03483.12 EIE87670.1 - 0.12 11.8 1.0 0.17 11.2 0.7 1.3 1 0 0 1 1 1 0 B3/4 domain PspB PF06667.7 EIE87670.1 - 4.8 7.1 7.5 1.1 9.2 1.1 2.7 1 1 1 2 2 2 0 Phage shock protein B RNA_pol_Rpb5_N PF03871.9 EIE87671.1 - 2.2e-20 72.8 0.0 4.4e-20 71.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain RNA_pol_Rpb5_C PF01191.14 EIE87671.1 - 2.3e-07 30.2 0.9 5.5e-07 29.0 0.6 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain Mrr_cat PF04471.7 EIE87671.1 - 0.093 12.5 0.0 0.12 12.1 0.0 1.3 1 1 0 1 1 1 0 Restriction endonuclease C1_1 PF00130.17 EIE87673.1 - 0.019 14.6 0.1 0.019 14.6 0.1 1.2 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-CCHC_4 PF14392.1 EIE87673.1 - 0.057 13.1 0.3 0.078 12.6 0.2 1.2 1 0 0 1 1 1 0 Zinc knuckle Cas1_AcylT PF07779.7 EIE87674.1 - 4.3e-150 500.4 34.6 6.2e-150 499.9 24.0 1.1 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p PC-Esterase PF13839.1 EIE87674.1 - 8e-28 97.9 0.1 1.2e-27 97.3 0.0 1.3 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p GTP_EFTU PF00009.22 EIE87675.1 - 2e-18 66.4 0.0 3.2e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain cobW PF02492.14 EIE87675.1 - 0.00029 20.3 0.2 0.0034 16.8 0.1 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 EIE87675.1 - 0.00029 20.3 0.2 2.4 7.6 0.0 3.4 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.22 EIE87675.1 - 0.00039 20.7 0.0 0.0012 19.1 0.0 1.8 2 0 0 2 2 1 1 ABC transporter GTP_EFTU_D2 PF03144.20 EIE87675.1 - 0.0012 18.9 0.1 0.0047 16.9 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 DUF258 PF03193.11 EIE87675.1 - 0.0032 16.6 0.2 0.0063 15.7 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EIE87675.1 - 0.0058 16.5 0.0 0.02 14.8 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase DAP3 PF10236.4 EIE87675.1 - 0.014 14.3 0.2 0.027 13.4 0.0 1.5 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 GTP_EFTU_D3 PF03143.12 EIE87675.1 - 0.018 15.2 0.0 0.043 13.9 0.0 1.7 1 0 0 1 1 1 0 Elongation factor Tu C-terminal domain ATP_bind_1 PF03029.12 EIE87675.1 - 0.018 14.5 0.4 3.7 7.0 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NACHT PF05729.7 EIE87675.1 - 0.032 13.8 0.0 0.069 12.7 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Miro PF08477.8 EIE87675.1 - 0.037 14.5 1.5 0.16 12.4 0.0 2.8 3 0 0 3 3 3 0 Miro-like protein AAA_29 PF13555.1 EIE87675.1 - 0.079 12.4 0.1 0.31 10.5 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain MobB PF03205.9 EIE87675.1 - 0.095 12.3 0.1 0.33 10.6 0.0 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ISN1 PF06437.6 EIE87676.1 - 0.013 14.2 0.2 0.015 14.0 0.1 1.3 1 1 0 1 1 1 0 IMP-specific 5'-nucleotidase Pkinase PF00069.20 EIE87677.1 - 1.9e-36 125.5 0.1 3e-35 121.6 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE87677.1 - 1.3e-27 96.5 0.0 3.1e-26 91.9 0.0 2.5 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE87677.1 - 0.0022 17.0 0.0 0.08 11.8 0.0 2.3 2 0 0 2 2 2 1 Kinase-like DUF1241 PF06840.6 EIE87677.1 - 0.024 13.8 0.1 0.054 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1241) Asp_protease PF09668.5 EIE87678.1 - 0.0032 17.0 0.2 0.013 15.0 0.0 1.8 2 0 0 2 2 2 1 Aspartyl protease IDEAL PF08858.5 EIE87678.1 - 0.057 12.9 0.1 0.14 11.7 0.1 1.7 1 0 0 1 1 1 0 IDEAL domain FTR PF01913.13 EIE87678.1 - 0.075 12.7 0.0 0.088 12.5 0.0 1.3 1 1 0 1 1 1 0 Formylmethanofuran-tetrahydromethanopterin formyltransferase LIX1 PF14954.1 EIE87678.1 - 0.075 11.9 0.2 0.089 11.7 0.1 1.1 1 0 0 1 1 1 0 Limb expression 1 Ubiquitin_2 PF14560.1 EIE87679.1 - 0.0042 17.2 0.1 0.0084 16.3 0.1 1.5 1 1 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.18 EIE87679.1 - 0.014 14.7 0.3 0.028 13.8 0.1 1.5 2 0 0 2 2 2 0 Ubiquitin family TIG PF01833.19 EIE87680.1 - 1.1e-12 47.7 0.0 3.3e-12 46.2 0.0 1.9 1 0 0 1 1 1 1 IPT/TIG domain eIF3g PF12353.3 EIE87682.1 - 5.4e-33 113.6 5.5 8.9e-33 112.9 3.8 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 EIE87682.1 - 1.8e-19 69.1 0.1 3.2e-19 68.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE87682.1 - 1.4e-13 50.5 0.0 2.7e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE87682.1 - 4.7e-10 39.1 0.1 8.4e-10 38.3 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.6 EIE87682.1 - 0.041 13.8 0.0 0.087 12.8 0.0 1.6 1 1 0 1 1 1 0 RNA binding domain SPOR PF05036.8 EIE87682.1 - 0.1 12.7 0.4 0.45 10.6 0.0 2.2 2 0 0 2 2 2 0 Sporulation related domain DivIC PF04977.10 EIE87683.1 - 0.0014 18.0 2.3 0.0024 17.2 1.6 1.3 1 0 0 1 1 1 1 Septum formation initiator SlyX PF04102.7 EIE87683.1 - 0.0087 16.4 1.6 0.018 15.3 1.1 1.5 1 0 0 1 1 1 1 SlyX TMF_TATA_bd PF12325.3 EIE87683.1 - 0.023 14.4 0.2 0.031 13.9 0.1 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 EIE87683.1 - 0.045 13.5 1.1 0.065 13.0 0.8 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Dapper PF15268.1 EIE87683.1 - 0.056 12.2 1.9 0.081 11.7 1.3 1.2 1 0 0 1 1 1 0 Dapper IncA PF04156.9 EIE87683.1 - 0.13 11.8 2.5 0.2 11.2 1.7 1.2 1 0 0 1 1 1 0 IncA protein TPR_MLP1_2 PF07926.7 EIE87683.1 - 0.19 11.4 2.9 0.34 10.6 2.0 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein HALZ PF02183.13 EIE87683.1 - 0.95 9.2 4.7 2.9 7.6 2.7 2.0 1 1 0 1 1 1 0 Homeobox associated leucine zipper bZIP_2 PF07716.10 EIE87683.1 - 3.2 7.6 5.2 7.4 6.4 3.6 1.7 1 1 0 1 1 1 0 Basic region leucine zipper UCH PF00443.24 EIE87684.1 - 1.9e-65 220.6 7.3 2.5e-65 220.2 5.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EIE87684.1 - 3.2e-28 99.0 17.1 1.9e-22 80.0 5.4 2.7 2 1 1 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 EIE87684.1 - 0.03 13.6 9.1 0.016 14.4 2.2 2.7 3 0 0 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Ribosomal_S11 PF00411.14 EIE87685.1 - 7.8e-26 90.4 0.4 9e-26 90.2 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S11 Arf PF00025.16 EIE87686.1 - 2.8e-47 160.2 0.5 3.4e-47 159.9 0.3 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EIE87686.1 - 5.7e-22 77.8 0.0 6.9e-22 77.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIE87686.1 - 3.4e-12 46.8 0.0 5.7e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 EIE87686.1 - 1.3e-11 44.1 0.0 1.5e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EIE87686.1 - 8.5e-11 41.3 0.1 9.8e-11 41.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EIE87686.1 - 1.1e-09 37.5 0.3 1.6e-07 30.4 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.18 EIE87686.1 - 5.2e-09 36.0 0.2 8.9e-09 35.3 0.0 1.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EIE87686.1 - 4e-08 32.9 0.1 2.1e-06 27.3 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain cobW PF02492.14 EIE87686.1 - 0.0013 18.1 0.1 0.23 10.9 0.0 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain DNA_pol3_delta2 PF13177.1 EIE87686.1 - 0.0044 16.7 0.2 0.0072 16.0 0.2 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Dynamin_N PF00350.18 EIE87686.1 - 0.0052 16.6 0.1 0.39 10.5 0.1 2.3 1 1 1 2 2 2 1 Dynamin family AAA_22 PF13401.1 EIE87686.1 - 0.021 14.9 0.1 0.089 12.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EIE87686.1 - 0.041 14.1 0.8 0.12 12.6 0.5 1.7 1 1 0 1 1 1 0 ABC transporter MobB PF03205.9 EIE87686.1 - 0.11 12.2 0.1 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 EIE87686.1 - 0.14 12.0 0.0 0.27 11.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.13 EIE87686.1 - 0.17 11.1 4.7 1.6 7.9 3.3 2.2 1 1 0 1 1 1 0 Ferrous iron transport protein B DNA_methylase PF00145.12 EIE87687.1 - 1.1e-31 110.1 0.3 1.3e-31 109.9 0.2 1.0 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase PSP PF04046.11 EIE87689.1 - 1.1e-13 50.2 0.3 2.5e-13 49.1 0.2 1.6 1 0 0 1 1 1 1 PSP zf-CCHC PF00098.18 EIE87689.1 - 0.0015 18.3 2.9 0.003 17.4 2.0 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 EIE87689.1 - 0.68 9.6 5.0 0.65 9.7 1.0 2.4 2 0 0 2 2 2 0 Zinc knuckle Mito_carr PF00153.22 EIE87690.1 - 8.3e-41 137.6 0.5 7.8e-21 73.5 0.1 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein WW PF00397.21 EIE87691.1 - 0.0026 17.5 0.8 0.0055 16.5 0.6 1.6 1 0 0 1 1 1 1 WW domain DUF605 PF04652.11 EIE87691.1 - 4.7 6.5 17.9 7.2 5.8 12.4 1.2 1 0 0 1 1 1 0 Vta1 like GDC-P PF02347.11 EIE87692.1 - 6.6e-203 674.1 0.3 1.6e-187 623.4 0.1 2.7 3 0 0 3 3 3 2 Glycine cleavage system P-protein Aminotran_5 PF00266.14 EIE87692.1 - 2.2e-08 33.2 0.3 1.5e-05 23.9 0.0 2.3 2 0 0 2 2 2 2 Aminotransferase class-V Beta_elim_lyase PF01212.16 EIE87692.1 - 0.00014 21.0 1.5 0.00061 19.0 0.0 2.6 3 1 0 3 3 3 1 Beta-eliminating lyase Aa_trans PF01490.13 EIE87694.1 - 9.5e-78 261.4 37.5 1.1e-77 261.2 26.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF3808 PF10300.4 EIE87695.1 - 1.1e-08 34.1 0.5 1.3e-08 33.9 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) Membralin PF09746.4 EIE87696.1 - 0.13 11.2 3.7 0.16 10.9 2.6 1.1 1 0 0 1 1 1 0 Tumour-associated protein DUF2672 PF10878.3 EIE87696.1 - 0.31 10.7 3.3 0.7 9.6 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2672) YyzF PF14116.1 EIE87698.1 - 0.0017 18.2 2.0 0.015 15.2 0.3 2.2 2 0 0 2 2 2 1 YyzF-like protein PRANC PF09372.5 EIE87698.1 - 0.0092 15.9 1.2 0.054 13.4 0.5 1.9 1 1 1 2 2 2 1 PRANC domain DUF1279 PF06916.8 EIE87699.1 - 0.14 12.5 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1279) RNA_pol_Rpb2_6 PF00562.23 EIE87700.1 - 1.8e-128 428.6 0.0 2.9e-128 427.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EIE87700.1 - 2.4e-67 225.8 0.0 3.5e-67 225.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EIE87700.1 - 6.9e-47 159.3 0.0 5.2e-46 156.4 0.0 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EIE87700.1 - 9.3e-32 109.1 0.1 3.1e-31 107.4 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 EIE87700.1 - 2e-26 91.5 0.1 4.5e-26 90.4 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.12 EIE87700.1 - 2.9e-23 81.5 0.2 6.7e-23 80.4 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_3 PF04565.11 EIE87700.1 - 9.4e-23 79.7 0.0 1.9e-22 78.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 DUF3947 PF13135.1 EIE87700.1 - 5.6 7.2 8.2 0.85 9.8 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3947) ABC_tran PF00005.22 EIE87701.1 - 1.3e-48 164.7 0.0 6.8e-27 94.4 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EIE87701.1 - 2.8e-48 164.7 36.4 4.5e-25 88.5 7.2 3.9 4 0 0 4 4 4 3 ABC transporter transmembrane region SMC_N PF02463.14 EIE87701.1 - 1.4e-08 34.2 8.4 0.00017 20.8 0.1 4.5 4 1 0 4 4 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EIE87701.1 - 4.9e-08 33.2 2.3 0.0023 17.9 0.1 4.7 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EIE87701.1 - 3.8e-06 26.3 1.5 0.015 14.8 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 EIE87701.1 - 1.6e-05 24.4 0.1 0.024 14.1 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family T2SE PF00437.15 EIE87701.1 - 3.3e-05 22.9 0.0 0.028 13.3 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_25 PF13481.1 EIE87701.1 - 7e-05 22.3 0.1 0.09 12.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EIE87701.1 - 0.0004 20.4 0.0 1.2 9.1 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain Miro PF08477.8 EIE87701.1 - 0.0012 19.3 5.4 0.018 15.5 0.0 3.5 3 0 0 3 3 3 1 Miro-like protein MMR_HSR1 PF01926.18 EIE87701.1 - 0.0028 17.6 0.3 1.6 8.7 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_17 PF13207.1 EIE87701.1 - 0.016 16.0 3.2 19 6.1 1.8 3.6 3 0 0 3 3 2 0 AAA domain Dynamin_N PF00350.18 EIE87701.1 - 0.032 14.0 0.2 0.032 14.0 0.1 2.9 3 0 0 3 3 3 0 Dynamin family DUF87 PF01935.12 EIE87701.1 - 0.037 13.8 8.3 0.68 9.7 0.2 3.0 3 0 0 3 3 3 0 Domain of unknown function DUF87 DUF258 PF03193.11 EIE87701.1 - 0.038 13.1 0.6 0.25 10.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 EIE87701.1 - 0.041 14.0 2.3 12 6.0 0.0 3.4 2 1 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.4 EIE87701.1 - 0.05 12.2 0.4 1.3 7.5 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_10 PF12846.2 EIE87701.1 - 0.053 12.9 1.5 7.3 5.9 0.1 2.5 2 1 0 2 2 2 0 AAA-like domain Zeta_toxin PF06414.7 EIE87701.1 - 0.059 12.4 0.0 0.65 9.0 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin ATP_bind_1 PF03029.12 EIE87701.1 - 0.077 12.5 2.0 9.8 5.6 0.1 3.2 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein MobB PF03205.9 EIE87701.1 - 0.095 12.4 0.4 18 5.0 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EIE87701.1 - 0.13 12.1 0.0 2.7 7.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EIE87701.1 - 0.17 12.1 0.0 0.17 12.1 0.0 4.2 5 1 0 5 5 3 0 AAA domain AAA_18 PF13238.1 EIE87701.1 - 0.37 11.1 3.7 14 6.0 0.1 3.9 4 0 0 4 4 3 0 AAA domain DUF2013 PF09431.5 EIE87703.1 - 8.5e-22 77.4 2.9 2.2e-10 40.4 0.4 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF2013) BHD_3 PF10405.4 EIE87704.1 - 2.6e-25 87.9 0.1 6.8e-25 86.5 0.0 1.8 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 Rad4 PF03835.10 EIE87704.1 - 1.5e-20 73.1 1.1 1.5e-20 73.1 0.8 2.2 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_1 PF10403.4 EIE87704.1 - 4.9e-20 70.7 0.2 1.4e-19 69.2 0.1 1.9 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 EIE87704.1 - 2.9e-13 49.9 0.9 2.2e-11 43.8 0.1 3.7 3 0 0 3 3 3 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 EIE87704.1 - 8.5e-05 22.7 0.0 0.00032 20.8 0.0 2.1 1 1 0 1 1 1 1 Transglutaminase-like superfamily Phage_holin PF04688.8 EIE87704.1 - 0.023 14.2 0.5 0.085 12.3 0.4 2.0 1 0 0 1 1 1 0 Phage lysis protein, holin DUF3321 PF11968.3 EIE87705.1 - 4.8e-40 137.5 0.0 7e-40 136.9 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase (DUF3321) Methyltransf_11 PF08241.7 EIE87705.1 - 0.015 15.7 0.0 0.036 14.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 EIE87705.1 - 0.1 12.3 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Brix PF04427.13 EIE87706.1 - 1.3e-51 174.9 0.2 1.7e-51 174.6 0.1 1.1 1 0 0 1 1 1 1 Brix domain Bromodomain PF00439.20 EIE87706.1 - 0.049 13.5 0.0 0.088 12.7 0.0 1.5 1 1 0 1 1 1 0 Bromodomain TPR_11 PF13414.1 EIE87707.1 - 8.1e-24 83.0 7.0 5.7e-10 38.7 0.2 3.6 2 1 1 3 3 3 3 TPR repeat TPR_1 PF00515.23 EIE87707.1 - 1.3e-20 72.0 6.4 0.00038 19.9 0.0 5.9 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 EIE87707.1 - 1.2e-17 62.3 5.0 0.0011 18.7 0.1 5.9 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 EIE87707.1 - 5.1e-15 55.6 3.5 1.1e-05 25.9 0.1 4.1 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_17 PF13431.1 EIE87707.1 - 4.7e-13 48.2 6.6 0.0025 17.8 0.1 5.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 EIE87707.1 - 2.7e-12 46.1 3.7 0.0028 18.1 0.8 4.8 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 EIE87707.1 - 1.6e-11 44.3 3.4 0.0018 18.5 0.0 3.8 2 1 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 EIE87707.1 - 3.6e-10 38.8 1.1 0.029 14.1 0.1 5.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 EIE87707.1 - 1.4e-08 34.5 3.2 0.0013 18.6 0.1 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_20 PF14561.1 EIE87707.1 - 2.9e-07 30.5 6.4 0.058 13.5 0.0 4.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 EIE87707.1 - 3.3e-07 29.5 1.5 0.14 11.9 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 EIE87707.1 - 6.6e-07 29.3 5.5 4.1e-05 23.6 0.2 2.5 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EIE87707.1 - 9.1e-05 22.6 4.4 0.68 10.5 0.1 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.1 EIE87707.1 - 0.00029 20.6 0.8 0.61 9.9 0.0 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat ChAPs PF09295.5 EIE87707.1 - 0.0006 18.6 0.1 0.029 13.1 0.0 2.2 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) DUF4248 PF14053.1 EIE87707.1 - 0.0083 15.6 0.3 0.16 11.5 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4248) DUF1641 PF07849.6 EIE87707.1 - 0.0094 15.5 0.1 0.22 11.1 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1641) TPR_10 PF13374.1 EIE87707.1 - 0.051 13.5 0.7 0.71 9.8 0.2 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat ERCC4 PF02732.10 EIE87708.1 - 5.2e-13 48.9 1.3 6.1e-13 48.7 0.9 1.2 1 0 0 1 1 1 1 ERCC4 domain PH_11 PF15413.1 EIE87708.1 - 0.058 13.6 0.5 0.096 12.9 0.2 1.6 1 1 0 1 1 1 0 Pleckstrin homology domain Dala_Dala_lig_N PF01820.16 EIE87709.1 - 4.3 7.6 7.3 2.5 8.4 2.7 2.3 2 1 0 2 2 2 0 D-ala D-ala ligase N-terminus Proteasome PF00227.21 EIE87710.1 - 1.1e-40 138.9 0.0 1.2e-40 138.8 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Proteasome PF00227.21 EIE87711.1 - 2.1e-37 128.2 0.2 2.9e-37 127.8 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Snurportin1 PF11538.3 EIE87712.1 - 0.0055 16.4 3.5 0.016 14.9 2.4 1.8 1 0 0 1 1 1 1 Snurportin1 Chordopox_G3 PF06129.7 EIE87712.1 - 0.039 14.0 0.7 0.074 13.2 0.5 1.5 1 0 0 1 1 1 0 Chordopoxvirus G3 protein DUF4595 PF15283.1 EIE87712.1 - 0.5 10.0 5.3 0.9 9.1 3.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4595) with porin-like fold RRN3 PF05327.6 EIE87712.1 - 1.6 6.7 7.8 1.2 7.1 4.3 1.4 1 1 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 AIF_C PF14721.1 EIE87712.1 - 5.7 7.1 6.1 1.6 8.9 0.9 2.0 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Peptidase_C14 PF00656.17 EIE87713.1 - 1.3e-43 149.4 0.1 2.7e-43 148.4 0.0 1.3 1 1 0 1 1 1 1 Caspase domain Snf7 PF03357.16 EIE87714.1 - 8.3e-22 77.3 12.9 1.4e-21 76.6 9.0 1.3 1 0 0 1 1 1 1 Snf7 Corona_S2 PF01601.11 EIE87714.1 - 0.029 12.4 1.0 0.046 11.8 0.7 1.3 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Sen15 PF09631.5 EIE87714.1 - 0.044 14.0 5.4 0.18 12.0 0.2 2.8 2 1 0 2 2 2 0 Sen15 protein Cytochrom_C PF00034.16 EIE87714.1 - 0.23 12.3 1.0 8.3 7.3 0.0 3.0 3 0 0 3 3 3 0 Cytochrome c NPV_P10 PF05531.7 EIE87714.1 - 0.73 10.1 6.1 2.5 8.4 0.0 3.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein MCPVI PF02993.9 EIE87714.1 - 2.7 8.0 8.2 0.81 9.7 2.8 1.9 1 1 1 2 2 2 0 Minor capsid protein VI DUF947 PF06102.7 EIE87714.1 - 4.2 7.1 10.9 0.046 13.5 1.3 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF947) CTDII PF01556.13 EIE87715.1 - 4.6e-25 87.3 3.3 3.7e-22 78.0 0.0 2.6 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EIE87715.1 - 9.1e-13 48.0 21.9 1.7e-12 47.2 15.2 1.5 1 0 0 1 1 1 1 DnaJ central domain DnaJ PF00226.26 EIE87715.1 - 1.2e-12 47.4 0.4 2.1e-12 46.5 0.3 1.4 1 0 0 1 1 1 1 DnaJ domain HypA PF01155.14 EIE87715.1 - 5.4e-05 22.8 5.1 0.016 14.9 0.5 2.3 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family SRI PF08236.6 EIE87716.1 - 0.2 11.6 0.1 0.2 11.6 0.1 2.7 2 1 0 2 2 2 0 SRI (Set2 Rpb1 interacting) domain HNH PF01844.18 EIE87718.1 - 0.0022 17.8 0.0 0.0031 17.3 0.0 1.3 1 0 0 1 1 1 1 HNH endonuclease Aldose_epim PF01263.15 EIE87720.1 - 0.11 11.5 0.3 0.12 11.4 0.2 1.1 1 0 0 1 1 1 0 Aldose 1-epimerase Kei1 PF08552.6 EIE87721.1 - 0.00014 21.5 9.8 0.00018 21.2 0.7 2.1 1 1 1 2 2 2 2 Inositolphosphorylceramide synthase subunit Kei1 AMP-binding PF00501.23 EIE87722.1 - 1.8e-75 253.8 0.0 2.5e-75 253.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EIE87722.1 - 1.7e-69 233.5 0.0 2.6e-69 232.9 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 EIE87722.1 - 5.4e-14 52.2 0.0 1.2e-13 51.0 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EIE87722.1 - 2.6e-12 47.4 0.0 7.7e-12 45.9 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.14 EIE87722.1 - 1.8e-11 43.3 0.0 3e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EIE87722.1 - 2e-10 40.4 0.0 3.9e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Condensation PF00668.15 EIE87722.1 - 7.5e-08 31.5 0.0 1.4e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Condensation domain adh_short PF00106.20 EIE87722.1 - 0.0022 17.9 0.1 0.012 15.5 0.1 2.3 1 1 0 1 1 1 1 short chain dehydrogenase zf-H2C2_2 PF13465.1 EIE87723.1 - 1.1e-07 31.7 1.3 1.1e-07 31.7 0.9 2.5 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EIE87723.1 - 0.00086 19.4 5.9 0.63 10.5 0.9 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EIE87723.1 - 0.0011 19.2 10.5 0.076 13.3 0.5 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EIE87723.1 - 0.034 14.0 0.2 0.089 12.7 0.1 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger DUF1935 PF09149.5 EIE87725.1 - 0.13 12.2 0.0 0.21 11.5 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1935) Longin PF13774.1 EIE87726.1 - 2e-32 110.5 0.2 3e-32 109.9 0.1 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 EIE87726.1 - 4.3e-15 55.0 0.0 7.5e-15 54.3 0.0 1.4 1 0 0 1 1 1 1 Synaptobrevin Imm42 PF15601.1 EIE87726.1 - 0.058 12.8 1.6 0.15 11.4 0.1 2.1 3 0 0 3 3 3 0 Immunity protein 42 Bystin PF05291.6 EIE87727.1 - 2.5e-138 460.1 0.5 2.5e-138 460.1 0.4 1.6 2 0 0 2 2 2 1 Bystin Beta-Casp PF10996.3 EIE87727.1 - 0.071 13.0 0.1 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 Beta-Casp domain Pkinase PF00069.20 EIE87728.1 - 1.1e-55 188.5 0.0 2.2e-55 187.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE87728.1 - 1e-40 139.4 0.0 1.8e-40 138.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Laminin_II PF06009.7 EIE87728.1 - 0.014 15.1 0.9 0.041 13.6 0.6 1.8 1 0 0 1 1 1 0 Laminin Domain II OSR1_C PF12202.3 EIE87728.1 - 0.027 14.0 0.2 0.063 12.9 0.1 1.6 1 0 0 1 1 1 0 Oxidative-stress-responsive kinase 1 C terminal Tropomyosin_1 PF12718.2 EIE87728.1 - 0.98 9.2 13.4 2.2 8.1 9.3 1.6 1 0 0 1 1 1 0 Tropomyosin like Phlebovirus_NSM PF07246.6 EIE87728.1 - 1.4 8.0 6.5 1.6 7.8 3.7 1.6 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M IncA PF04156.9 EIE87728.1 - 6.3 6.3 10.3 12 5.3 7.2 1.5 1 0 0 1 1 1 0 IncA protein DUF1127 PF06568.6 EIE87728.1 - 6.4 6.2 7.3 20 4.6 1.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1127) zf-RING_2 PF13639.1 EIE87729.1 - 7.1e-13 48.1 4.7 1.2e-12 47.4 3.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EIE87729.1 - 4.8e-09 36.0 5.0 8.5e-09 35.3 3.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EIE87729.1 - 4.7e-07 29.3 3.3 8.1e-07 28.6 2.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIE87729.1 - 6.1e-07 28.9 5.4 1.1e-06 28.1 3.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIE87729.1 - 1.1e-06 28.2 4.5 2e-06 27.4 3.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 EIE87729.1 - 1.5e-06 28.2 4.6 2.9e-06 27.2 3.2 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 EIE87729.1 - 2.3e-05 24.0 4.6 6.2e-05 22.6 3.2 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-Apc11 PF12861.2 EIE87729.1 - 5.6e-05 22.8 1.5 0.00011 21.9 1.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 EIE87729.1 - 0.00069 19.4 3.6 0.00069 19.4 2.5 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING DUF3393 PF11873.3 EIE87729.1 - 0.0014 18.2 3.5 0.0083 15.6 0.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3393) RINGv PF12906.2 EIE87729.1 - 0.0024 17.8 5.3 0.0049 16.8 3.6 1.6 1 0 0 1 1 1 1 RING-variant domain Nup54 PF13874.1 EIE87729.1 - 0.0088 15.7 0.2 0.0088 15.7 0.1 2.4 2 1 0 2 2 2 1 Nucleoporin complex subunit 54 Tropomyosin_1 PF12718.2 EIE87729.1 - 0.022 14.6 5.2 0.022 14.6 3.6 2.2 2 0 0 2 2 2 0 Tropomyosin like zf-Nse PF11789.3 EIE87729.1 - 0.031 13.7 2.2 0.065 12.7 1.5 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit WEMBL PF05701.6 EIE87729.1 - 0.034 12.6 13.5 0.031 12.7 2.2 2.0 2 0 0 2 2 2 0 Weak chloroplast movement under blue light DUF4200 PF13863.1 EIE87729.1 - 0.042 13.7 17.4 0.15 11.9 3.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Mod_r PF07200.8 EIE87729.1 - 0.054 13.4 12.5 0.043 13.7 2.4 2.4 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein FANCL_C PF11793.3 EIE87729.1 - 0.061 13.2 5.1 0.2 11.6 3.5 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain NAGidase PF07555.8 EIE87729.1 - 0.078 11.8 4.1 1.6 7.5 0.3 2.1 2 0 0 2 2 2 0 beta-N-acetylglucosaminidase GAS PF13851.1 EIE87729.1 - 0.19 10.9 18.2 0.75 8.9 2.7 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding IncA PF04156.9 EIE87729.1 - 0.23 11.0 12.6 0.062 12.8 3.5 2.2 2 0 0 2 2 2 0 IncA protein Hormone_1 PF00103.15 EIE87729.1 - 0.26 10.5 7.3 0.31 10.3 1.1 2.2 2 0 0 2 2 2 0 Somatotropin hormone family PHD PF00628.24 EIE87729.1 - 0.34 10.6 3.0 0.84 9.3 2.1 1.7 1 0 0 1 1 1 0 PHD-finger zf-RING_4 PF14570.1 EIE87729.1 - 0.41 10.2 2.1 0.97 9.0 1.4 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_1 PF14446.1 EIE87729.1 - 0.74 9.5 4.1 0.52 10.0 0.4 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 Peptidase_U57 PF05582.7 EIE87729.1 - 1 8.2 8.7 0.19 10.6 0.3 2.1 2 0 0 2 2 2 0 YabG peptidase U57 Bap31 PF05529.7 EIE87729.1 - 1.4 8.3 8.2 2.9 7.3 1.3 2.2 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like DUF3373 PF11853.3 EIE87729.1 - 1.8 6.9 6.7 1.2 7.5 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3373) LMBR1 PF04791.11 EIE87729.1 - 2.4 6.6 8.4 1.5 7.3 1.1 2.1 2 0 0 2 2 2 0 LMBR1-like membrane protein Prok-RING_4 PF14447.1 EIE87729.1 - 2.7 7.6 5.9 21 4.7 4.1 2.2 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Rootletin PF15035.1 EIE87729.1 - 5.1 7.0 15.1 1.9 8.3 1.1 2.2 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion DUF1664 PF07889.7 EIE87729.1 - 5.3 6.8 7.2 1.8 8.3 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF3552 PF12072.3 EIE87729.1 - 5.3 6.2 19.4 5.5 6.1 4.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) Ax_dynein_light PF10211.4 EIE87729.1 - 5.5 6.7 15.6 7.1 6.4 3.3 2.2 2 0 0 2 2 2 0 Axonemal dynein light chain DUF904 PF06005.7 EIE87729.1 - 6.5 7.1 17.1 11 6.3 3.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF904) DUF948 PF06103.6 EIE87729.1 - 8.2 6.3 7.2 5.5 6.9 0.5 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) WD40 PF00400.27 EIE87730.1 - 4.1e-41 137.4 10.4 1.6e-11 43.6 0.1 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EIE87730.1 - 5.1e-05 22.1 3.5 0.058 12.1 0.8 3.1 2 1 0 2 2 2 2 Nup133 N terminal like Nup160 PF11715.3 EIE87730.1 - 0.31 9.1 4.0 0.29 9.2 0.1 2.7 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Fib_alpha PF08702.5 EIE87732.1 - 1.1 9.3 5.8 1.6 8.8 0.4 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family OrfB_Zn_ribbon PF07282.6 EIE87734.1 - 0.02 14.5 0.1 0.33 10.6 0.0 2.4 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Lebercilin PF15619.1 EIE87735.1 - 0.026 13.9 1.9 0.037 13.4 1.3 1.2 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Herpes_BLRF2 PF05812.7 EIE87735.1 - 0.035 13.9 0.2 0.056 13.2 0.1 1.3 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein DivIC PF04977.10 EIE87735.1 - 0.047 13.1 2.8 0.083 12.3 2.0 1.3 1 0 0 1 1 1 0 Septum formation initiator TSC22 PF01166.13 EIE87735.1 - 0.067 13.1 0.7 0.11 12.5 0.5 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family HALZ PF02183.13 EIE87735.1 - 0.11 12.1 0.5 0.28 10.9 0.4 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper Pneumo_att_G PF05539.6 EIE87735.1 - 1.2 8.4 5.8 1.5 8.1 4.0 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Ammonium_transp PF00909.16 EIE87737.1 - 3.3e-107 358.4 18.7 3.8e-107 358.2 13.0 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family SNN_linker PF09050.5 EIE87738.1 - 0.13 11.8 0.2 0.19 11.3 0.1 1.3 1 0 0 1 1 1 0 Stannin unstructured linker Helicase_IV_N PF12462.3 EIE87739.1 - 0.042 13.5 0.5 0.063 12.9 0.3 1.2 1 0 0 1 1 1 0 DNA helicase IV / RNA helicase N terminal DivIC PF04977.10 EIE87739.1 - 0.043 13.2 0.8 0.07 12.6 0.6 1.3 1 0 0 1 1 1 0 Septum formation initiator DUF3422 PF11902.3 EIE87739.1 - 0.068 12.0 0.4 0.12 11.2 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3422) Mak10 PF04112.8 EIE87740.1 - 1.1e-25 89.7 1.0 9.4e-24 83.5 0.7 2.4 1 1 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase tRNA-Thr_ED PF08915.6 EIE87740.1 - 0.015 15.2 0.0 0.032 14.2 0.0 1.5 1 0 0 1 1 1 0 Archaea-specific editing domain of threonyl-tRNA synthetase DUF3449 PF11931.3 EIE87741.1 - 2.9e-72 242.3 6.1 2.9e-72 242.3 4.2 2.7 2 1 0 3 3 3 1 Domain of unknown function (DUF3449) SF3a60_bindingd PF12108.3 EIE87741.1 - 1.4e-11 43.6 1.0 4.7e-11 42.0 0.7 2.0 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-met PF12874.2 EIE87741.1 - 6.5e-09 35.6 3.5 3.1e-06 27.1 1.0 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EIE87741.1 - 2.1e-06 27.6 1.5 2.1e-06 27.6 1.0 3.0 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EIE87741.1 - 0.00028 20.9 0.1 0.00028 20.9 0.1 3.6 4 0 0 4 4 4 1 C2H2 type zinc-finger (2 copies) Interferon PF00143.14 EIE87741.1 - 0.65 9.8 6.6 0.31 10.8 0.4 2.3 2 0 0 2 2 2 0 Interferon alpha/beta domain zf-C2H2_4 PF13894.1 EIE87741.1 - 1.2 9.5 3.9 24 5.5 0.2 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EIE87741.1 - 1.3 9.5 3.8 13 6.3 0.3 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type Glyco_transf_34 PF05637.7 EIE87742.1 - 5.5e-15 55.5 0.2 1.2e-14 54.3 0.1 1.6 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.9 EIE87742.1 - 3.3e-06 26.5 0.0 7.5e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF273 YhdB PF14148.1 EIE87742.1 - 0.037 13.7 3.6 0.09 12.5 2.5 1.6 1 0 0 1 1 1 0 YhdB-like protein JSRP PF15312.1 EIE87742.1 - 0.31 11.0 1.3 1.5 8.8 0.2 2.6 2 1 1 3 3 3 0 Junctional sarcoplasmic reticulum protein ELYS PF13934.1 EIE87744.1 - 0.019 14.6 0.0 0.087 12.5 0.0 1.7 1 1 1 2 2 2 0 Nuclear pore complex assembly RVT_1 PF00078.22 EIE87745.1 - 3e-29 101.9 0.0 5.9e-29 100.9 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_3 PF13358.1 EIE87746.1 - 4.1e-32 110.9 0.0 1.2e-31 109.4 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_29 PF13551.1 EIE87746.1 - 4.4e-09 36.4 0.0 1e-08 35.3 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.1 EIE87746.1 - 1.2e-06 29.2 0.0 6.1e-06 26.9 0.0 2.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.1 EIE87746.1 - 5.4e-06 26.2 0.2 3.3e-05 23.7 0.0 2.3 3 0 0 3 3 2 1 Helix-turn-helix domain HTH_23 PF13384.1 EIE87746.1 - 0.00057 19.4 0.0 0.0032 17.0 0.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain rve PF00665.21 EIE87746.1 - 0.00077 19.5 0.0 0.0034 17.4 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain DDE_1 PF03184.14 EIE87746.1 - 0.0015 17.6 0.1 0.025 13.7 0.1 2.3 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_1 PF01527.15 EIE87746.1 - 0.0055 16.6 1.1 0.2 11.6 0.1 2.5 2 0 0 2 2 2 1 Transposase HTH_Tnp_Tc3_2 PF01498.13 EIE87746.1 - 0.0069 16.4 0.1 0.021 14.9 0.1 1.9 1 0 0 1 1 1 1 Transposase HTH_17 PF12728.2 EIE87746.1 - 0.018 15.2 0.0 0.82 9.9 0.0 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_30 PF13556.1 EIE87746.1 - 0.044 13.3 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain Terminase_5 PF06056.7 EIE87746.1 - 0.082 12.4 0.0 0.25 10.8 0.0 1.8 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) C2 PF00168.25 EIE87747.1 - 7.6e-23 80.1 0.3 1e-22 79.7 0.2 1.2 1 0 0 1 1 1 1 C2 domain NT-C2 PF10358.4 EIE87747.1 - 0.018 14.5 0.2 0.029 13.8 0.2 1.4 1 1 0 1 1 1 0 N-terminal C2 in EEIG1 and EHBP1 proteins DOCK-C2 PF14429.1 EIE87747.1 - 0.035 13.7 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 C2 domain in Dock180 and Zizimin proteins Ecl1 PF12855.2 EIE87748.1 - 7.6e-06 25.1 5.1 7.6e-06 25.1 3.5 1.8 2 0 0 2 2 2 1 Life-span regulatory factor Metallothio_Pro PF02069.11 EIE87748.1 - 3.1 7.6 8.1 11 5.9 3.9 2.6 2 1 0 2 2 2 0 Prokaryotic metallothionein zf-MYND PF01753.13 EIE87748.1 - 7.1 6.6 9.4 0.81 9.6 3.3 1.8 2 0 0 2 2 2 0 MYND finger CCDC84 PF14968.1 EIE87748.1 - 8 5.8 8.2 4.1 6.8 4.3 1.4 2 0 0 2 2 2 0 Coiled coil protein 84 WD40 PF00400.27 EIE87749.1 - 4.8e-30 102.3 18.1 2.2e-09 36.8 0.1 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat DUF3337 PF11816.3 EIE87749.1 - 1.4e-20 73.9 0.3 5e-20 72.1 0.2 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF3337) DUF3601 PF12208.3 EIE87749.1 - 0.12 12.2 0.0 3.5 7.6 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3601) VID27 PF08553.5 EIE87749.1 - 0.22 9.7 0.1 0.35 9.0 0.1 1.2 1 0 0 1 1 1 0 VID27 cytoplasmic protein rve PF00665.21 EIE87751.1 - 2.1e-16 60.0 0.0 8.8e-16 58.1 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 EIE87751.1 - 2e-11 43.6 1.3 3.9e-10 39.4 0.3 3.0 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE87751.1 - 3e-08 33.1 3.4 7.2e-08 31.9 0.2 2.8 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain RVP PF00077.15 EIE87751.1 - 0.0034 17.2 0.1 0.014 15.3 0.0 2.1 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 EIE87751.1 - 0.027 14.9 0.1 0.056 13.9 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease Retrotrans_gag PF03732.12 EIE87751.1 - 0.033 14.2 0.0 0.24 11.4 0.0 2.5 1 0 0 1 1 1 0 Retrotransposon gag protein RVT_1 PF00078.22 EIE87752.1 - 5.8e-18 65.0 0.6 2.2e-17 63.1 0.2 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 EIE87752.1 - 0.024 14.9 0.0 0.057 13.7 0.0 1.6 1 0 0 1 1 1 0 RNase H DUF1875 PF08961.5 EIE87753.1 - 0.03 13.6 1.2 0.034 13.4 0.2 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1875) Fmp27_WPPW PF10359.4 EIE87753.1 - 0.03 12.7 0.8 0.046 12.1 0.5 1.3 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF4407 PF14362.1 EIE87753.1 - 0.77 8.6 6.4 1 8.2 4.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HTH_Tnp_Tc3_2 PF01498.13 EIE87754.1 - 4.1e-06 26.7 1.2 4.9e-06 26.5 0.8 1.3 1 1 0 1 1 1 1 Transposase HTH_Tnp_Tc3_2 PF01498.13 EIE87755.1 - 4.5e-08 33.0 0.0 5.7e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Transposase DUF2642 PF10842.3 EIE87755.1 - 0.042 13.3 0.1 0.16 11.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2642) RVT_1 PF00078.22 EIE87757.1 - 0.00038 19.8 0.0 0.00066 19.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Inhibitor_I10 PF12559.3 EIE87758.1 - 0.29 11.4 1.7 1.2 9.4 0.0 2.2 2 0 0 2 2 2 0 Serine endopeptidase inhibitors Retrotrans_gag PF03732.12 EIE87759.1 - 2e-06 27.7 0.7 8.4e-06 25.7 0.0 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein Asp_protease_2 PF13650.1 EIE87759.1 - 3.1e-06 27.5 0.0 9e-06 26.1 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease UBN2_2 PF14227.1 EIE87759.1 - 2.6e-05 23.7 0.9 0.00042 19.8 0.1 3.1 3 1 0 3 3 3 1 gag-polypeptide of LTR copia-type gag-asp_proteas PF13975.1 EIE87759.1 - 9.8e-05 22.1 0.0 0.0002 21.0 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease UBN2 PF14223.1 EIE87759.1 - 0.00016 21.4 1.0 0.1 12.3 0.1 2.5 2 0 0 2 2 2 2 gag-polypeptide of LTR copia-type RVT_1 PF00078.22 EIE87760.1 - 4.3e-15 55.6 0.1 7.9e-15 54.7 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EIE87760.1 - 2.4e-14 53.4 0.0 7.8e-13 48.5 0.0 2.6 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.5 EIE87760.1 - 0.0045 16.3 0.1 0.0093 15.3 0.0 1.6 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Chromo PF00385.19 EIE87761.1 - 2.6e-12 46.1 0.1 4.8e-12 45.3 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.21 EIE87761.1 - 0.0069 16.4 0.0 0.018 15.1 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 EIE87761.1 - 0.068 12.6 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain rve PF00665.21 EIE87762.1 - 2.1e-13 50.4 0.1 1.1e-11 44.8 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.1 EIE87762.1 - 0.00026 20.4 0.0 0.00045 19.6 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Poxvirus_B22R_N PF13169.1 EIE87762.1 - 0.19 11.9 1.5 14 5.9 0.3 2.2 2 0 0 2 2 2 0 Poxvirus B22R protein N-terminal DDE_3 PF13358.1 EIE87763.1 - 8.9e-19 67.6 0.0 1.6e-18 66.8 0.0 1.4 1 1 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE87763.1 - 0.049 13.7 0.0 0.058 13.5 0.0 1.2 1 0 0 1 1 1 0 Integrase core domain RNA_pol_Rpb1_5 PF04998.12 EIE87764.1 - 4.9e-83 278.5 1.2 8e-83 277.8 0.9 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 EIE87764.1 - 7.5e-78 262.1 0.0 1.1e-77 261.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 EIE87764.1 - 7.4e-70 234.2 0.1 7e-69 231.0 0.0 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EIE87764.1 - 8.5e-38 129.5 0.0 5.3e-37 126.9 0.0 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 EIE87764.1 - 4.6e-30 103.5 0.1 1.2e-29 102.1 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Chitin_synth_2 PF03142.10 EIE87765.1 - 4.1e-243 807.5 2.1 5.7e-243 807.0 1.5 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 EIE87765.1 - 6.3e-12 45.6 7.8 6.3e-12 45.6 5.4 2.3 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EIE87765.1 - 8.1e-10 38.8 0.0 2.6e-09 37.2 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 EIE87765.1 - 5.2e-06 26.1 0.0 4.2e-05 23.2 0.0 2.2 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glyco_transf_21 PF13506.1 EIE87765.1 - 0.0098 15.1 0.1 1.1 8.5 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 21 FA_desaturase PF00487.19 EIE87765.1 - 3 7.1 8.6 0.78 9.1 2.8 2.2 2 0 0 2 2 2 0 Fatty acid desaturase Homeobox PF00046.24 EIE87766.1 - 7.4e-19 67.1 0.8 1.7e-18 65.9 0.6 1.7 1 0 0 1 1 1 1 Homeobox domain HTH_23 PF13384.1 EIE87766.1 - 0.0031 17.1 0.3 0.0072 15.9 0.2 1.6 1 0 0 1 1 1 1 Homeodomain-like domain Homeobox_KN PF05920.6 EIE87766.1 - 0.0064 16.1 0.9 0.1 12.3 0.0 2.4 2 0 0 2 2 2 1 Homeobox KN domain DUF3500 PF12006.3 EIE87766.1 - 0.092 11.6 0.1 0.15 10.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3500) AAA_30 PF13604.1 EIE87766.1 - 0.35 10.4 1.3 10 5.6 0.0 2.5 3 0 0 3 3 3 0 AAA domain SMC_Nse1 PF07574.8 EIE87767.1 - 0.0026 17.4 0.0 0.0026 17.4 0.0 1.0 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex DWNN PF08783.6 EIE87768.1 - 3.1e-13 49.4 0.2 8.1e-13 48.1 0.0 1.8 2 0 0 2 2 2 1 DWNN domain zf-CCHC_2 PF13696.1 EIE87768.1 - 1.3e-08 34.1 5.4 1.3e-08 34.1 3.8 1.8 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC PF00098.18 EIE87768.1 - 1.3e-05 24.9 2.5 3.8e-05 23.4 1.7 1.9 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 EIE87768.1 - 0.00063 19.4 1.0 0.0016 18.1 0.7 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-C3HC4_2 PF13923.1 EIE87768.1 - 0.0026 17.7 8.4 0.0026 17.7 5.9 2.8 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EIE87768.1 - 0.12 12.0 17.0 0.027 14.1 7.6 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 EIE87768.1 - 1.7 8.2 10.7 4.5 6.9 7.4 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.1 EIE87768.1 - 1.8 8.4 19.5 0.06 13.1 8.6 2.2 3 0 0 3 3 3 0 Ring finger domain zf-RING_5 PF14634.1 EIE87768.1 - 3.9 7.2 18.1 0.36 10.5 7.6 2.3 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4 PF00097.20 EIE87768.1 - 9.9 5.9 19.3 0.05 13.2 7.0 2.1 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Actin PF00022.14 EIE87769.1 - 2.2e-142 474.1 0.0 2.5e-142 473.9 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EIE87769.1 - 3e-05 22.7 0.0 0.012 14.2 0.0 2.6 2 1 0 2 2 2 2 MreB/Mbl protein Hydantoinase_A PF01968.13 EIE87769.1 - 0.26 10.3 1.7 0.28 10.2 0.1 1.7 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase Cpn60_TCP1 PF00118.19 EIE87770.1 - 4.7e-137 457.5 0.8 5.9e-137 457.2 0.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Pkinase PF00069.20 EIE87771.1 - 1.5e-70 237.3 0.0 1.8e-70 237.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE87771.1 - 2.7e-37 128.2 0.0 3.2e-37 128.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE87771.1 - 0.0013 17.7 0.0 0.0037 16.2 0.0 1.7 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 EIE87771.1 - 0.0069 15.4 0.3 0.012 14.6 0.2 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EIE87771.1 - 0.057 12.7 0.0 0.084 12.2 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Seadorna_VP7 PF07387.6 EIE87771.1 - 0.11 11.3 0.0 0.17 10.6 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 DUF724 PF05266.9 EIE87772.1 - 0.019 14.5 5.4 0.022 14.3 3.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF2746 PF10874.3 EIE87772.1 - 0.047 13.8 1.6 0.074 13.2 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) TMF_DNA_bd PF12329.3 EIE87772.1 - 0.072 12.8 4.8 0.13 12.0 3.3 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF342 PF03961.8 EIE87772.1 - 0.08 11.3 1.5 0.079 11.3 1.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) GBP_C PF02841.9 EIE87772.1 - 0.1 11.7 4.4 0.1 11.7 3.1 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain UPF0449 PF15136.1 EIE87772.1 - 0.16 12.1 1.1 0.19 11.9 0.8 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 DUF904 PF06005.7 EIE87772.1 - 0.28 11.5 6.8 0.41 10.9 4.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF904) CaM_binding PF07839.6 EIE87772.1 - 0.28 11.3 4.7 0.32 11.2 3.2 1.1 1 0 0 1 1 1 0 Plant calmodulin-binding domain DUF972 PF06156.8 EIE87772.1 - 0.59 10.4 3.3 0.76 10.1 2.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF972) DivIC PF04977.10 EIE87772.1 - 0.62 9.5 5.2 0.88 9.1 3.6 1.2 1 0 0 1 1 1 0 Septum formation initiator TAF8_C PF10406.4 EIE87772.1 - 0.93 9.5 3.5 18 5.4 0.0 2.5 2 1 1 3 3 3 0 Transcription factor TFIID complex subunit 8 C-term HALZ PF02183.13 EIE87772.1 - 1.9 8.2 6.3 4.1 7.2 3.0 2.2 1 1 1 2 2 2 0 Homeobox associated leucine zipper Kinesin PF00225.18 EIE87773.1 - 1.8e-81 273.4 0.1 6.8e-81 271.5 0.1 2.1 1 0 0 1 1 1 1 Kinesin motor domain IncA PF04156.9 EIE87773.1 - 0.00036 20.1 0.4 0.00036 20.1 0.3 6.4 4 1 1 6 6 6 3 IncA protein DUF2205 PF10224.4 EIE87774.1 - 0.003 17.1 7.6 0.003 17.1 5.3 2.9 2 1 1 3 3 3 1 Predicted coiled-coil protein (DUF2205) TPR_MLP1_2 PF07926.7 EIE87774.1 - 0.025 14.3 24.2 0.035 13.8 16.7 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein bZIP_1 PF00170.16 EIE87774.1 - 0.037 13.9 0.9 0.037 13.9 0.6 3.8 3 2 0 3 3 3 0 bZIP transcription factor Hist_deacetyl PF00850.14 EIE87774.1 - 0.13 11.4 0.7 0.5 9.5 0.0 1.8 1 1 1 2 2 2 0 Histone deacetylase domain DUF972 PF06156.8 EIE87774.1 - 0.16 12.3 21.2 2.5 8.5 6.7 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF972) Reo_sigmaC PF04582.7 EIE87774.1 - 0.24 10.5 4.3 0.45 9.6 3.0 1.4 1 1 0 1 1 1 0 Reovirus sigma C capsid protein NAD_binding_6 PF08030.7 EIE87774.1 - 0.38 10.6 4.4 0.48 10.3 3.0 1.1 1 0 0 1 1 1 0 Ferric reductase NAD binding domain DUF4252 PF14060.1 EIE87774.1 - 0.39 10.2 4.5 0.18 11.3 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4252) Snapin_Pallidin PF14712.1 EIE87774.1 - 0.47 10.7 20.6 2.8 8.2 0.5 3.3 1 1 3 4 4 4 0 Snapin/Pallidin Salt_tol_Pase PF09506.5 EIE87774.1 - 0.53 8.7 5.0 0.94 7.9 3.3 1.4 1 1 1 2 2 2 0 Glucosylglycerol-phosphate phosphatase (Salt_tol_Pase) TMCO5 PF14992.1 EIE87774.1 - 0.63 9.1 22.5 0.036 13.1 8.7 1.9 1 1 1 2 2 2 0 TMCO5 family AlaDh_PNT_C PF01262.16 EIE87774.1 - 0.84 9.1 3.0 2.3 7.7 0.1 2.0 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain DUF2730 PF10805.3 EIE87774.1 - 1.1 9.0 9.9 10 5.9 2.9 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2730) DUF641 PF04859.7 EIE87774.1 - 3.2 7.5 13.8 2 8.1 6.0 2.6 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) EAP30 PF04157.11 EIE87774.1 - 3.8 6.5 11.4 3.9 6.5 6.0 2.1 1 1 0 2 2 2 0 EAP30/Vps36 family Ax_dynein_light PF10211.4 EIE87774.1 - 4.9 6.9 21.5 1.8 8.3 7.4 2.2 1 1 1 2 2 2 0 Axonemal dynein light chain IncA PF04156.9 EIE87774.1 - 5.8 6.4 33.2 1.8 8.1 4.2 2.2 1 1 1 2 2 2 0 IncA protein Phlebovirus_NSM PF07246.6 EIE87774.1 - 6.1 5.9 12.6 2 7.4 7.0 1.4 1 1 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DUF2935 PF11155.3 EIE87774.1 - 6.4 6.8 10.2 6.7 6.8 5.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) TBPIP PF07106.8 EIE87774.1 - 6.4 6.2 24.3 13 5.2 7.1 2.8 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Pkinase PF00069.20 EIE87775.1 - 3.5e-66 223.0 0.0 5.1e-66 222.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE87775.1 - 5.1e-32 110.9 0.0 8e-32 110.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.2 EIE87775.1 - 5.4e-21 74.7 0.0 6.5e-14 52.0 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EIE87775.1 - 1e-15 57.3 0.0 3e-11 43.1 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 EIE87775.1 - 2.5e-15 55.3 0.0 5.3e-09 35.4 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.1 EIE87775.1 - 1.3e-14 52.8 0.0 6.6e-08 32.0 0.0 4.9 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.1 EIE87775.1 - 5.6e-14 52.2 0.0 2.4e-08 34.2 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Kinase-like PF14531.1 EIE87775.1 - 2.6e-06 26.6 0.0 0.00011 21.3 0.0 2.2 1 1 1 2 2 2 1 Kinase-like DUF4251 PF14059.1 EIE87775.1 - 0.033 13.9 0.1 0.054 13.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4251) APH PF01636.18 EIE87775.1 - 0.097 12.3 0.0 0.27 10.9 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family DAO PF01266.19 EIE87776.1 - 1.6e-39 135.8 0.0 1.8e-39 135.6 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EIE87776.1 - 0.00042 20.4 0.1 0.0028 17.7 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EIE87776.1 - 0.00099 18.1 0.1 0.29 9.9 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Mqo PF06039.10 EIE87776.1 - 0.0018 16.5 0.0 0.0089 14.2 0.0 1.8 2 0 0 2 2 2 1 Malate:quinone oxidoreductase (Mqo) NAD_binding_9 PF13454.1 EIE87776.1 - 0.0064 16.2 0.3 1.4 8.6 0.1 2.4 2 1 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox PF00070.22 EIE87776.1 - 0.014 15.7 0.0 1.8 9.0 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EIE87776.1 - 0.038 14.0 0.1 0.15 12.0 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain NAD_Gly3P_dh_N PF01210.18 EIE87776.1 - 0.1 12.3 0.0 2.4 7.8 0.0 2.2 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_8 PF13450.1 EIE87776.1 - 0.11 12.4 0.0 0.28 11.2 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain zf-H2C2_2 PF13465.1 EIE87777.1 - 9.2e-08 32.0 5.9 4.9e-07 29.7 0.4 3.9 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.21 EIE87777.1 - 1.1e-05 25.4 17.6 5.8e-05 23.1 2.0 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIE87777.1 - 0.0011 19.1 1.4 0.0011 19.1 0.9 3.6 3 1 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.2 EIE87777.1 - 0.0056 16.8 9.0 0.014 15.5 2.2 2.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type Methyltransf_11 PF08241.7 EIE87779.1 - 1.2e-17 64.1 0.1 2.8e-17 62.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIE87779.1 - 1.1e-12 48.0 0.0 1.8e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIE87779.1 - 1.2e-12 48.4 0.0 2.1e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIE87779.1 - 8e-10 39.0 0.0 1.7e-09 38.0 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIE87779.1 - 1.3e-09 37.8 0.0 2.1e-09 37.1 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIE87779.1 - 3e-07 29.8 0.0 4.8e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EIE87779.1 - 7.6e-07 29.4 0.0 1.3e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 EIE87779.1 - 1.1e-05 24.6 0.0 1.6e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 EIE87779.1 - 0.00015 21.7 0.0 0.00063 19.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.11 EIE87779.1 - 0.00026 19.4 0.0 0.00055 18.3 0.0 1.6 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_PK PF05891.7 EIE87779.1 - 0.00057 19.2 0.0 0.0027 17.0 0.0 1.9 2 0 0 2 2 2 1 AdoMet dependent proline di-methyltransferase MTS PF05175.9 EIE87779.1 - 0.00082 18.7 0.0 0.0029 16.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain TehB PF03848.9 EIE87779.1 - 0.00093 18.4 0.0 0.0023 17.1 0.0 1.6 1 1 0 1 1 1 1 Tellurite resistance protein TehB DREV PF05219.7 EIE87779.1 - 0.038 12.8 0.0 0.063 12.1 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_8 PF05148.10 EIE87779.1 - 0.043 13.4 0.0 0.062 12.9 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase Oxidored_FMN PF00724.15 EIE87780.1 - 1.1e-104 350.1 0.0 1.2e-104 349.9 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family FHA PF00498.21 EIE87781.1 - 3.6e-13 49.4 0.1 8.9e-13 48.1 0.1 1.7 1 1 0 1 1 1 1 FHA domain Phage_portal_2 PF05136.8 EIE87781.1 - 0.066 11.7 0.0 0.098 11.1 0.0 1.2 1 0 0 1 1 1 0 Phage portal protein, lambda family Filo_VP35 PF02097.10 EIE87781.1 - 0.093 11.9 2.3 0.16 11.1 1.6 1.4 1 0 0 1 1 1 0 Filoviridae VP35 Spc7 PF08317.6 EIE87781.1 - 2.6 6.6 22.7 0.77 8.3 13.8 1.6 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF4164 PF13747.1 EIE87781.1 - 3.6 7.7 11.3 10 6.3 2.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) IncA PF04156.9 EIE87781.1 - 4.1 6.9 18.0 7 6.1 12.4 1.3 1 0 0 1 1 1 0 IncA protein FlaC_arch PF05377.6 EIE87781.1 - 4.8 7.1 9.5 6.8 6.6 2.8 2.7 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) EIF_2_alpha PF07541.7 EIE87783.1 - 3.2e-42 142.8 0.2 8.3e-42 141.5 0.0 1.8 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 EIE87783.1 - 1e-12 47.9 3.1 2.2e-12 46.9 1.2 2.2 2 0 0 2 2 2 1 S1 RNA binding domain EXOSC1 PF10447.4 EIE87783.1 - 0.039 13.8 0.4 0.13 12.2 0.1 2.1 2 1 0 2 2 2 0 Exosome component EXOSC1/CSL4 p450 PF00067.17 EIE87784.1 - 6.1e-80 268.9 0.0 8.3e-80 268.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Pil1 PF13805.1 EIE87785.1 - 6.8e-33 113.9 2.2 8.6e-33 113.6 1.5 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 Syntaxin PF00804.20 EIE87785.1 - 0.043 13.9 2.8 0.1 12.7 1.9 1.6 1 0 0 1 1 1 0 Syntaxin Phage_HK97_TLTM PF06120.6 EIE87785.1 - 0.072 12.4 0.8 0.12 11.7 0.6 1.2 1 0 0 1 1 1 0 Tail length tape measure protein DivIC PF04977.10 EIE87785.1 - 0.44 10.0 5.8 0.21 11.0 2.0 1.8 1 1 0 1 1 1 0 Septum formation initiator Cyclase PF04199.8 EIE87787.1 - 4.9e-14 52.3 0.0 7.5e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 Putative cyclase EF-hand_6 PF13405.1 EIE87788.1 - 5.9e-23 78.6 7.9 2.1e-06 27.1 0.2 4.9 4 1 0 4 4 4 4 EF-hand domain EF-hand_1 PF00036.27 EIE87788.1 - 2e-22 76.6 14.6 1.7e-06 26.8 0.0 4.6 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 EIE87788.1 - 5e-22 77.8 4.7 3.4e-14 52.7 0.4 2.7 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 EIE87788.1 - 7.5e-17 59.8 13.8 1.6e-05 23.9 0.6 4.5 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 EIE87788.1 - 1e-11 44.2 18.5 6.8e-07 28.8 0.9 4.0 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.2 EIE87788.1 - 7.7e-08 32.0 6.5 0.083 12.6 0.1 4.0 2 1 2 4 4 4 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EIE87788.1 - 8.4e-06 25.7 1.3 0.0038 17.2 0.1 2.9 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region S10_plectin PF03501.10 EIE87788.1 - 0.011 15.6 0.0 0.02 14.7 0.0 1.5 1 1 0 1 1 1 0 Plectin/S10 domain EF-hand_9 PF14658.1 EIE87788.1 - 0.013 15.4 0.5 3.9 7.4 0.0 3.6 3 1 0 3 3 3 0 EF-hand domain Toprim PF01751.17 EIE87788.1 - 0.013 15.4 0.0 2.2 8.3 0.0 2.5 1 1 0 2 2 2 0 Toprim domain Toprim_2 PF13155.1 EIE87788.1 - 0.078 13.3 0.7 3.2 8.1 0.1 2.9 1 1 1 2 2 2 0 Toprim-like EF-hand_10 PF14788.1 EIE87788.1 - 0.25 11.0 4.4 14 5.4 0.0 4.1 4 1 0 4 4 4 0 EF hand DAG_kinase_N PF14513.1 EIE87788.1 - 0.39 10.9 3.4 0.86 9.7 2.1 1.8 1 1 0 1 1 1 0 Diacylglycerol kinase N-terminus Methyltransf_11 PF08241.7 EIE87789.1 - 3.6e-10 40.1 0.0 5.1e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIE87789.1 - 3.2e-09 36.5 0.0 6.7e-09 35.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIE87789.1 - 1.1e-06 27.9 0.0 1.5e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.10 EIE87789.1 - 1.1e-05 25.2 0.0 1.2e-05 25.0 0.0 1.2 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_25 PF13649.1 EIE87789.1 - 9.1e-05 22.7 0.0 0.00018 21.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIE87789.1 - 0.00022 20.9 0.0 0.00029 20.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIE87789.1 - 0.00029 21.2 0.0 0.00044 20.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.13 EIE87789.1 - 0.00054 19.3 0.0 0.00067 19.0 0.0 1.1 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain Methyltransf_26 PF13659.1 EIE87789.1 - 0.0073 16.3 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.11 EIE87789.1 - 0.017 13.4 0.0 0.021 13.1 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_18 PF12847.2 EIE87789.1 - 0.033 14.7 0.0 0.052 14.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain TPMT PF05724.6 EIE87789.1 - 0.034 13.5 0.0 0.042 13.2 0.0 1.1 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) DUF1456 PF07308.8 EIE87790.1 - 0.016 15.2 1.2 0.034 14.1 0.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1456) BRCA2 PF00634.13 EIE87792.1 - 5e-09 35.2 9.4 4.1e-06 25.9 0.2 4.1 4 0 0 4 4 4 2 BRCA2 repeat PTRF_SDPR PF15237.1 EIE87792.1 - 1.4 8.3 11.0 0.034 13.5 2.6 2.0 2 1 1 3 3 3 0 PTRF/SDPR family Stm1_N PF09598.5 EIE87792.1 - 3.3 8.4 7.1 1.2 9.8 0.1 2.8 2 1 0 2 2 2 0 Stm1 BRCA-2_OB1 PF09103.5 EIE87793.1 - 3.4e-22 78.3 0.0 6.8e-22 77.3 0.0 1.5 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 Oxidored_FMN PF00724.15 EIE87794.1 - 1.1e-105 353.4 0.0 1.2e-105 353.2 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Oxidored_FMN PF00724.15 EIE87795.1 - 1.7e-105 352.7 0.0 2e-105 352.5 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pkinase PF00069.20 EIE87797.1 - 1.5e-66 224.2 0.0 1.9e-66 223.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE87797.1 - 1.4e-35 122.6 0.0 2.2e-35 122.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIE87797.1 - 5.4e-05 23.0 0.0 0.00074 19.3 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EIE87797.1 - 0.012 15.2 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kinase-like PF14531.1 EIE87797.1 - 0.015 14.3 0.0 0.1 11.5 0.0 2.1 2 1 0 2 2 2 0 Kinase-like Kdo PF06293.9 EIE87797.1 - 0.017 14.1 0.0 0.028 13.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EIE87797.1 - 0.035 13.4 0.1 0.067 12.5 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Pyridoxal_deC PF00282.14 EIE87798.1 - 1.9e-18 66.0 0.0 3e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Ribosomal_L21p PF00829.16 EIE87798.1 - 1.2e-09 38.1 0.1 2.5e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein Aminotran_5 PF00266.14 EIE87798.1 - 1.9e-07 30.2 0.0 5e-07 28.7 0.0 1.7 2 1 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EIE87798.1 - 7.6e-07 28.4 0.2 1.2e-06 27.7 0.2 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Dor1 PF04124.7 EIE87798.1 - 0.067 11.6 0.0 0.11 10.9 0.0 1.3 1 0 0 1 1 1 0 Dor1-like family SPRY PF00622.23 EIE87799.1 - 1.2e-13 51.2 0.1 5.7e-11 42.5 0.0 2.5 2 0 0 2 2 2 2 SPRY domain adh_short PF00106.20 EIE87800.1 - 7.9e-15 55.1 0.0 2.3e-14 53.6 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIE87800.1 - 1.6e-05 24.7 0.1 2.1e-05 24.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIE87800.1 - 0.002 17.8 0.0 0.0053 16.4 0.0 1.7 1 1 0 1 1 1 1 KR domain DUF2604 PF10790.4 EIE87800.1 - 0.035 14.2 0.0 0.065 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of Unknown function (DUF2604) Aldo_ket_red PF00248.16 EIE87803.1 - 1.1e-61 208.2 0.0 1.2e-61 207.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Snf7 PF03357.16 EIE87804.1 - 1e-07 31.5 22.0 2.8e-07 30.0 15.3 1.7 1 1 0 1 1 1 1 Snf7 DUF3727 PF12527.3 EIE87804.1 - 0.48 10.5 6.6 0.37 10.9 3.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3727) Myc_N PF01056.13 EIE87804.1 - 2.3 7.3 6.1 2.2 7.3 0.9 2.0 2 0 0 2 2 2 0 Myc amino-terminal region Ribosomal_60s PF00428.14 EIE87804.1 - 7.3 7.0 9.9 13 6.2 6.8 1.5 1 1 0 1 1 1 0 60s Acidic ribosomal protein MatE PF01554.13 EIE87805.1 - 1.5e-30 105.9 21.9 5.4e-20 71.6 2.3 3.6 3 1 1 4 4 4 3 MatE KAR9 PF08580.5 EIE87805.1 - 1.1e-08 33.8 11.7 1.1e-08 33.8 8.1 3.1 2 1 1 3 3 3 2 Yeast cortical protein KAR9 Polysacc_synt_C PF14667.1 EIE87805.1 - 2.4e-08 33.8 5.5 2.4e-08 33.8 3.8 2.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis C-terminal domain GAS2 PF02187.12 EIE87805.1 - 3.9e-05 23.3 0.1 0.00031 20.4 0.0 2.4 3 0 0 3 3 3 1 Growth-Arrest-Specific Protein 2 Domain DUF745 PF05335.8 EIE87806.1 - 0.022 14.3 0.7 0.43 10.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF745) DUF3209 PF11483.3 EIE87806.1 - 0.11 12.7 2.1 0.12 12.7 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3209) Cortex-I_coil PF09304.5 EIE87806.1 - 0.4 10.7 3.9 5.8 7.0 0.2 2.4 1 1 1 2 2 2 0 Cortexillin I, coiled coil KxDL PF10241.4 EIE87806.1 - 0.5 10.2 2.9 2.1 8.2 0.4 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein TPR_MLP1_2 PF07926.7 EIE87806.1 - 3.8 7.2 9.5 0.48 10.1 2.4 2.5 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein LCAT PF02450.10 EIE87807.1 - 1.5e-74 251.3 6.4 2.7e-72 243.8 4.4 2.9 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase Lipase_2 PF01674.13 EIE87807.1 - 0.00069 18.9 0.1 0.0018 17.6 0.0 1.7 2 0 0 2 2 2 1 Lipase (class 2) Abhydrolase_5 PF12695.2 EIE87807.1 - 0.06 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family zf-RVT PF13966.1 EIE87808.1 - 0.00029 21.0 0.9 0.00053 20.2 0.6 1.5 1 1 0 1 1 1 1 zinc-binding in reverse transcriptase RVT_1 PF00078.22 EIE87809.1 - 2.4e-32 112.0 0.0 7.3e-32 110.4 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Osmo_MPGsynth PF09488.5 EIE87809.1 - 0.0013 17.5 0.1 0.0023 16.6 0.1 1.3 1 0 0 1 1 1 1 Mannosyl-3-phosphoglycerate synthase (osmo_MPGsynth) TMF_TATA_bd PF12325.3 EIE87810.1 - 1.2e-05 25.0 2.8 1.7e-05 24.4 0.9 2.0 2 0 0 2 2 2 1 TATA element modulatory factor 1 TATA binding CENP-F_leu_zip PF10473.4 EIE87810.1 - 0.00013 21.8 3.1 0.00039 20.2 2.1 1.9 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIVA PF05103.8 EIE87810.1 - 0.00014 21.8 4.6 0.00014 21.8 3.2 2.2 3 0 0 3 3 1 1 DivIVA protein Golgin_A5 PF09787.4 EIE87810.1 - 0.00056 18.5 7.0 0.00091 17.8 4.9 1.4 1 0 0 1 1 1 1 Golgin subfamily A member 5 DUF2296 PF10058.4 EIE87810.1 - 0.0025 17.5 0.6 0.0061 16.2 0.4 1.7 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) FliJ PF02050.11 EIE87810.1 - 0.016 15.2 6.9 0.016 15.2 4.8 2.0 3 0 0 3 3 1 0 Flagellar FliJ protein DUF948 PF06103.6 EIE87810.1 - 0.02 14.7 1.5 0.038 13.8 1.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Zn_Tnp_IS1 PF03811.8 EIE87810.1 - 0.046 13.2 5.5 0.1 12.0 3.8 1.6 1 0 0 1 1 1 0 InsA N-terminal domain DivIC PF04977.10 EIE87810.1 - 0.046 13.2 2.0 0.14 11.7 1.4 1.8 1 0 0 1 1 1 0 Septum formation initiator zf-CCHC PF00098.18 EIE87810.1 - 0.067 13.1 0.3 0.067 13.1 0.2 1.8 2 0 0 2 2 1 0 Zinc knuckle CCDC144C PF14915.1 EIE87810.1 - 0.085 11.7 10.0 0.14 11.0 7.0 1.3 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region TMF_DNA_bd PF12329.3 EIE87810.1 - 0.088 12.6 2.8 0.23 11.2 1.9 1.7 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding TBPIP PF07106.8 EIE87810.1 - 0.092 12.2 3.8 0.3 10.6 2.7 1.9 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) HR1 PF02185.11 EIE87810.1 - 0.096 12.4 4.9 0.14 11.8 1.9 2.4 2 0 0 2 2 2 0 Hr1 repeat Bap31 PF05529.7 EIE87810.1 - 0.11 11.9 2.7 0.27 10.6 1.9 1.6 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like GrpE PF01025.14 EIE87810.1 - 0.24 10.9 2.1 0.83 9.1 0.9 2.2 2 0 0 2 2 2 0 GrpE IncA PF04156.9 EIE87810.1 - 0.25 10.8 5.8 0.13 11.8 2.4 1.8 2 0 0 2 2 2 0 IncA protein Spc24 PF08286.6 EIE87810.1 - 0.35 10.5 4.8 0.087 12.5 0.7 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Zn_Tnp_IS1595 PF12760.2 EIE87810.1 - 0.53 10.1 5.1 1.2 9.0 3.5 1.6 1 0 0 1 1 1 0 Transposase zinc-ribbon domain V_ATPase_I PF01496.14 EIE87810.1 - 0.78 7.5 3.7 1.1 7.0 2.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FUSC PF04632.7 EIE87810.1 - 1.3 7.3 3.1 1.5 7.1 2.2 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Zn-ribbon_8 PF09723.5 EIE87810.1 - 1.5 8.8 5.8 16 5.5 0.0 2.8 2 1 0 2 2 2 0 Zinc ribbon domain DUF4407 PF14362.1 EIE87810.1 - 3.6 6.4 8.4 5.7 5.7 5.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4140 PF13600.1 EIE87810.1 - 4 7.9 7.4 0.59 10.6 0.9 2.4 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DDE_3 PF13358.1 EIE87814.1 - 6e-17 61.7 0.0 1.2e-16 60.7 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE87814.1 - 4.7e-08 32.9 3.2 8e-08 32.2 0.7 2.3 1 1 1 2 2 2 1 Transposase NUDIX_4 PF14815.1 EIE87814.1 - 0.013 14.9 0.3 0.024 14.0 0.2 1.4 1 0 0 1 1 1 0 NUDIX domain DDE_3 PF13358.1 EIE87815.1 - 1.6e-17 63.5 0.4 8.9e-17 61.1 0.0 2.3 3 0 0 3 3 3 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE87815.1 - 1.8e-11 43.9 0.6 4.1e-11 42.7 0.4 1.7 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.1 EIE87815.1 - 0.02 15.6 0.1 0.88 10.4 0.0 2.9 3 0 0 3 3 3 0 Homeodomain-like domain HTH_29 PF13551.1 EIE87815.1 - 0.04 14.0 0.0 0.11 12.6 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn helix rve PF00665.21 EIE87816.1 - 1.1e-23 83.6 0.0 3.2e-23 82.1 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE87816.1 - 6.9e-17 61.5 0.0 1.4e-16 60.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE87816.1 - 2.7e-10 39.7 0.6 2.7e-10 39.7 0.4 2.0 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.1 EIE87816.1 - 0.00019 21.8 0.3 0.00054 20.3 0.2 1.9 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.5 EIE87816.1 - 0.00021 20.6 0.0 0.00061 19.1 0.0 1.9 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger UBN2_2 PF14227.1 EIE87816.1 - 0.024 14.1 0.7 0.66 9.5 0.0 2.9 3 0 0 3 3 3 0 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EIE87816.1 - 0.061 13.1 0.4 0.19 11.5 0.0 2.0 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type Asp_protease PF09668.5 EIE87816.1 - 0.064 12.8 0.1 0.17 11.4 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.1 EIE87816.1 - 0.13 12.0 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Chromo PF00385.19 EIE87819.1 - 8.4e-12 44.5 0.6 1.9e-11 43.4 0.4 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Leader_Erm PF08253.6 EIE87820.1 - 0.33 10.4 0.3 0.33 10.4 0.2 2.1 2 0 0 2 2 2 0 Erm Leader peptide RVT_1 PF00078.22 EIE87821.1 - 5.2e-17 61.9 0.0 9.6e-17 61.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) UBN2_2 PF14227.1 EIE87821.1 - 0.0063 16.0 0.1 0.22 11.0 0.0 2.5 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EIE87821.1 - 0.053 13.3 0.2 0.19 11.4 0.0 2.0 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type rve PF00665.21 EIE87822.1 - 2.6e-20 72.7 0.0 1e-19 70.7 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 EIE87822.1 - 3.6e-11 42.8 0.3 1e-10 41.3 0.2 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE87822.1 - 4.5e-07 29.4 2.4 1.1e-06 28.2 1.6 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.1 EIE87822.1 - 8e-07 29.4 0.2 8.9e-06 26.1 0.1 2.4 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.15 EIE87822.1 - 1.9e-05 24.4 0.1 6.2e-05 22.8 0.0 1.9 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EIE87822.1 - 0.00011 21.9 0.0 0.00025 20.8 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Tudor-knot PF11717.3 EIE87822.1 - 0.0066 16.1 0.9 0.023 14.3 0.6 2.0 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Y2_Tnp PF04986.8 EIE87823.1 - 0.1 12.3 0.0 0.68 9.6 0.0 2.0 1 1 0 2 2 2 0 Putative transposase HTH_Tnp_Tc3_2 PF01498.13 EIE87826.1 - 8.8e-09 35.3 0.3 1.5e-08 34.5 0.2 1.3 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.1 EIE87826.1 - 0.019 14.7 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease rve PF00665.21 EIE87827.1 - 1.9e-24 86.1 0.0 5.7e-24 84.5 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE87827.1 - 6.9e-17 61.5 0.0 1.4e-16 60.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE87827.1 - 8.8e-11 41.3 0.6 2.6e-10 39.8 0.4 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 EIE87827.1 - 0.001 18.3 0.1 0.0028 17.0 0.1 1.8 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Asp_protease_2 PF13650.1 EIE87827.1 - 0.002 18.6 0.2 0.0055 17.1 0.1 1.8 1 0 0 1 1 1 1 Aspartyl protease UBN2_2 PF14227.1 EIE87827.1 - 0.0041 16.6 1.3 0.067 12.7 0.0 2.8 3 0 0 3 3 3 1 gag-polypeptide of LTR copia-type rve_3 PF13683.1 EIE87827.1 - 0.028 13.9 0.0 0.088 12.3 0.0 1.9 1 0 0 1 1 1 0 Integrase core domain UBN2 PF14223.1 EIE87827.1 - 0.032 14.0 0.4 0.091 12.5 0.0 1.9 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type Asp_protease PF09668.5 EIE87827.1 - 0.13 11.8 0.1 0.37 10.3 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease Chromo PF00385.19 EIE87829.1 - 1.3e-11 43.9 0.4 2.6e-11 43.0 0.3 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain S1_2 PF13509.1 EIE87829.1 - 0.071 13.0 0.1 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 S1 domain RVT_1 PF00078.22 EIE87830.1 - 2.4e-11 43.3 0.3 4.5e-11 42.5 0.2 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.12 EIE87830.1 - 0.00061 19.8 0.1 0.0022 17.9 0.1 1.9 1 0 0 1 1 1 1 Retrotransposon gag protein Sed5p PF11416.3 EIE87830.1 - 1.6 8.2 5.0 3.7 7.0 1.2 2.8 2 0 0 2 2 2 0 Integral membrane protein Sed5p HTH_23 PF13384.1 EIE87831.1 - 0.015 14.9 0.1 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain HTH_38 PF13936.1 EIE87831.1 - 0.097 12.2 0.1 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain DUF3420 PF11900.3 EIE87831.1 - 0.17 12.0 0.5 0.23 11.5 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3420) DDE_3 PF13358.1 EIE87832.1 - 5.4e-18 65.1 0.1 1.4e-17 63.8 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE87832.1 - 7e-09 35.6 0.6 3e-08 33.5 0.6 2.0 2 1 0 2 2 2 1 Transposase Retrotrans_gag PF03732.12 EIE87833.1 - 4e-15 55.6 0.1 7.5e-15 54.7 0.1 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein Phage_integrase PF00589.17 EIE87834.1 - 3.5e-05 23.5 0.0 3.7e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Phage integrase family tRNA_bind_2 PF13725.1 EIE87837.1 - 0.011 15.8 0.0 0.012 15.7 0.0 1.2 1 0 0 1 1 1 0 Possible tRNA binding domain Ribosomal_L28 PF00830.14 EIE87841.1 - 1.2e-22 79.5 1.5 2e-22 78.7 1.1 1.4 1 0 0 1 1 1 1 Ribosomal L28 family MethyltransfD12 PF02086.10 EIE87841.1 - 0.03 13.7 1.1 0.035 13.5 0.7 1.2 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase Chromo_shadow PF01393.14 EIE87842.1 - 1e-10 41.2 0.0 1.6e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Chromo shadow domain Imm45 PF15603.1 EIE87842.1 - 0.0098 16.0 0.8 0.033 14.3 0.2 1.9 1 1 1 2 2 2 1 Immunity protein 45 TPR_7 PF13176.1 EIE87842.1 - 0.099 12.4 0.2 56 3.8 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat SRP40_C PF05022.7 EIE87843.1 - 2.1e-27 95.4 3.4 8.3e-27 93.5 2.3 2.1 1 0 0 1 1 1 1 SRP40, C-terminal domain LisH PF08513.6 EIE87843.1 - 0.0066 16.1 0.1 0.011 15.4 0.1 1.4 1 0 0 1 1 1 1 LisH Ank PF00023.25 EIE87844.1 - 7.8e-14 50.6 1.9 1.4e-06 27.8 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 EIE87844.1 - 9.7e-14 51.4 0.1 2.1e-13 50.4 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) TIG PF01833.19 EIE87844.1 - 1.7e-13 50.3 0.3 4.2e-13 49.0 0.2 1.8 1 0 0 1 1 1 1 IPT/TIG domain Ank_5 PF13857.1 EIE87844.1 - 1.3e-12 47.4 4.0 2e-09 37.3 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIE87844.1 - 2.3e-10 39.6 0.6 9.2e-05 22.3 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 EIE87844.1 - 3.6e-09 36.8 0.4 8.6e-09 35.6 0.3 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) PseudoU_synth_2 PF00849.17 EIE87845.1 - 1e-06 28.6 0.1 1.4e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase Trypsin PF00089.21 EIE87846.1 - 3.3e-21 75.9 0.2 5.6e-21 75.1 0.0 1.5 2 0 0 2 2 2 1 Trypsin Trypsin_2 PF13365.1 EIE87846.1 - 0.00012 21.9 0.0 0.00023 21.1 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Actin PF00022.14 EIE87847.1 - 1.5e-162 540.5 0.0 1.7e-162 540.3 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 EIE87847.1 - 0.081 13.3 0.0 0.2 12.0 0.0 1.7 1 1 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) zf-H2C2 PF09337.5 EIE87848.1 - 0.014 14.7 0.2 0.023 14.0 0.1 1.4 1 0 0 1 1 1 0 His(2)-Cys(2) zinc finger Paxillin PF03535.8 EIE87848.1 - 0.045 13.5 2.4 0.088 12.6 1.7 1.4 1 0 0 1 1 1 0 Paxillin family Nro1 PF12753.2 EIE87849.1 - 3.7e-26 92.0 24.8 3.4e-21 75.6 3.3 2.2 1 1 0 2 2 2 2 Nuclear pore complex subunit Nro1 TPR_17 PF13431.1 EIE87849.1 - 2.1e-05 24.3 3.0 0.37 11.1 0.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EIE87849.1 - 0.0024 18.3 7.0 2 9.2 0.0 5.3 5 1 0 5 5 5 1 Tetratricopeptide repeat Cnd3 PF12719.2 EIE87849.1 - 0.0046 15.9 0.2 0.0083 15.1 0.1 1.6 1 0 0 1 1 1 1 Nuclear condensing complex subunits, C-term domain TPR_11 PF13414.1 EIE87849.1 - 0.0049 16.4 12.5 0.12 12.0 0.1 4.6 3 1 1 4 4 4 1 TPR repeat Med2 PF11214.3 EIE87849.1 - 0.017 15.1 3.5 0.017 15.1 2.5 2.7 1 1 1 2 2 2 0 Mediator complex subunit 2 Fis1_TPR_C PF14853.1 EIE87849.1 - 0.027 14.3 0.0 0.1 12.4 0.0 2.1 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat TPR_16 PF13432.1 EIE87849.1 - 0.045 14.4 0.0 0.045 14.4 0.0 5.2 6 1 0 6 6 6 0 Tetratricopeptide repeat NAD_binding_3 PF03447.11 EIE87849.1 - 0.049 14.0 0.4 0.049 14.0 0.3 2.5 2 0 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain TPR_19 PF14559.1 EIE87849.1 - 0.48 10.7 0.1 0.48 10.7 0.1 5.0 4 1 1 5 5 5 0 Tetratricopeptide repeat Peptidase_M13 PF01431.16 EIE87850.1 - 1e-68 230.5 0.0 1.4e-68 230.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13_N PF05649.8 EIE87850.1 - 4.2e-34 118.2 0.0 6.4e-34 117.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M48 PF01435.13 EIE87850.1 - 0.19 11.2 0.0 0.29 10.6 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M48 HLH PF00010.21 EIE87851.1 - 5e-15 54.9 1.4 2.9e-14 52.5 0.3 2.6 2 1 1 3 3 3 1 Helix-loop-helix DNA-binding domain PAP_assoc PF03828.14 EIE87852.1 - 1e-05 25.3 0.2 3.8e-05 23.5 0.0 2.2 2 0 0 2 2 2 1 Cid1 family poly A polymerase GAT PF03127.9 EIE87854.1 - 5.2e-06 26.3 0.1 6.6e-06 26.0 0.1 1.1 1 0 0 1 1 1 1 GAT domain PMEI PF04043.10 EIE87854.1 - 0.083 12.8 0.0 0.13 12.1 0.0 1.4 1 1 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor DUF3508 PF12018.3 EIE87854.1 - 0.085 11.8 0.5 0.1 11.5 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3508) DUF946 PF06101.6 EIE87855.1 - 0.052 11.5 0.0 0.074 11.0 0.0 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF946) RVT_1 PF00078.22 EIE87856.1 - 5.9e-27 94.4 0.0 1.4e-26 93.2 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EIE87856.1 - 7.1e-18 64.3 2.2 2.7e-17 62.4 1.5 2.1 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EIE87856.1 - 1.2e-07 31.9 0.1 2.8e-07 30.7 0.1 1.7 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Lar_restr_allev PF14354.1 EIE87856.1 - 0.018 15.3 1.5 0.039 14.2 0.4 2.1 2 0 0 2 2 2 0 Restriction alleviation protein Lar Zn_Tnp_IS1595 PF12760.2 EIE87856.1 - 0.19 11.5 2.4 0.61 9.9 1.6 1.9 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.5 EIE87856.1 - 0.56 10.2 2.4 23 5.0 0.1 2.7 2 0 0 2 2 2 0 Zinc ribbon domain DUF2296 PF10058.4 EIE87857.1 - 0.021 14.5 0.3 0.061 13.0 0.2 1.7 1 0 0 1 1 1 0 Predicted integral membrane metal-binding protein (DUF2296) DUF3450 PF11932.3 EIE87857.1 - 0.032 13.4 1.7 0.047 12.9 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) zf-ISL3 PF14690.1 EIE87857.1 - 0.059 13.4 1.0 0.8 9.7 0.2 2.4 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Zn-ribbon_8 PF09723.5 EIE87857.1 - 0.14 12.1 0.3 20 5.2 0.0 2.4 2 0 0 2 2 2 0 Zinc ribbon domain Ogr_Delta PF04606.7 EIE87857.1 - 0.35 10.5 2.5 18 5.1 0.2 2.4 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger zf-C2H2 PF00096.21 EIE87857.1 - 0.4 11.1 0.2 0.4 11.1 0.1 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIE87857.1 - 1.1 9.6 5.6 8.5 6.8 1.1 2.7 2 0 0 2 2 2 0 Zinc-finger double domain SlyX PF04102.7 EIE87857.1 - 1.3 9.4 5.2 0.26 11.7 0.5 2.2 3 0 0 3 3 3 0 SlyX DHDPS PF00701.17 EIE87859.1 - 4.8e-55 186.2 0.0 5.4e-55 186.0 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Glyco_transf_34 PF05637.7 EIE87860.1 - 2.2e-19 69.9 2.3 2.4e-18 66.5 1.6 2.3 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.9 EIE87860.1 - 1e-10 41.3 0.0 2.8e-10 39.8 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function, DUF273 Nucleotid_trans PF03407.11 EIE87860.1 - 0.0019 18.0 0.5 0.0047 16.7 0.1 1.9 2 0 0 2 2 2 1 Nucleotide-diphospho-sugar transferase DUF4131 PF13567.1 EIE87860.1 - 0.016 14.5 0.0 0.065 12.6 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Mak10 PF04112.8 EIE87861.1 - 4.1e-30 104.2 2.6 7.2e-30 103.4 1.8 1.4 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Glyco_trans_1_3 PF13528.1 EIE87862.1 - 0.014 14.6 0.0 0.25 10.5 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 1 CUE PF02845.11 EIE87863.1 - 0.0024 17.3 2.5 0.068 12.6 0.0 3.0 2 1 0 2 2 2 1 CUE domain OTU PF02338.14 EIE87863.1 - 0.0048 17.4 0.1 0.0048 17.4 0.1 2.6 2 1 0 2 2 2 1 OTU-like cysteine protease GAGA_bind PF06217.7 EIE87863.1 - 5.2 6.9 13.5 6.8 6.5 9.4 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family DUF1043 PF06295.7 EIE87865.1 - 0.0075 15.9 0.0 0.0076 15.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1043) PEP-utilisers_N PF05524.8 EIE87865.1 - 0.075 12.8 0.0 0.081 12.7 0.0 1.0 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal GAF_2 PF13185.1 EIE87869.1 - 1.6e-10 41.6 0.0 2.3e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 GAF domain GAF PF01590.21 EIE87869.1 - 4.3e-07 30.1 0.0 6.3e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.1 EIE87869.1 - 3.6e-05 23.8 0.0 5.3e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 GAF domain Pyridoxal_deC PF00282.14 EIE87871.1 - 4e-70 236.1 0.0 4.9e-70 235.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EIE87871.1 - 1.9e-06 26.8 0.0 3e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Chromate_transp PF02417.10 EIE87872.1 - 0.0056 16.2 10.8 0.27 10.7 0.4 2.2 2 0 0 2 2 2 2 Chromate transporter HIG_1_N PF04588.8 EIE87872.1 - 0.058 13.1 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Hypoxia induced protein conserved region Trp_oprn_chp PF09534.5 EIE87872.1 - 0.087 12.4 0.1 0.36 10.4 0.1 1.8 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF4131 PF13567.1 EIE87872.1 - 0.21 10.9 7.8 0.42 9.9 0.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) MFS_1 PF07690.11 EIE87872.1 - 2.5 6.7 11.6 3.9 6.0 1.4 2.3 1 1 0 2 2 2 0 Major Facilitator Superfamily MerC PF03203.9 EIE87872.1 - 2.9 8.2 7.1 0.37 11.1 0.5 2.3 2 1 0 2 2 2 0 MerC mercury resistance protein ERO1 PF04137.10 EIE87874.1 - 1.3e-120 402.7 1.9 1.7e-120 402.2 1.3 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) PAPS_reduct PF01507.14 EIE87875.1 - 1.4e-08 34.7 0.0 5.1e-07 29.6 0.0 2.3 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family Sec7 PF01369.15 EIE87877.1 - 9.8e-29 100.3 0.7 2.4e-28 99.1 0.3 1.8 2 0 0 2 2 2 1 Sec7 domain PH_9 PF15410.1 EIE87877.1 - 7.5e-24 84.1 0.0 2.4e-23 82.5 0.0 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 EIE87877.1 - 0.00013 22.1 0.0 0.00051 20.2 0.0 2.1 1 0 0 1 1 1 1 PH domain DUF3115 PF11312.3 EIE87879.1 - 4e-20 71.9 0.0 7e-20 71.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3115) CheR PF01739.13 EIE87879.1 - 0.0009 18.5 0.3 0.76 9.0 0.0 2.2 2 0 0 2 2 2 2 CheR methyltransferase, SAM binding domain IL10 PF00726.12 EIE87879.1 - 0.078 12.2 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Interleukin 10 DMRL_synthase PF00885.14 EIE87880.1 - 1.2e-43 148.2 0.4 2.9e-29 101.5 0.1 2.0 2 0 0 2 2 2 2 6,7-dimethyl-8-ribityllumazine synthase Spo0A_C PF08769.6 EIE87880.1 - 0.14 12.0 1.0 8.4 6.3 0.1 2.4 1 1 0 2 2 2 0 Sporulation initiation factor Spo0A C terminal Pkinase PF00069.20 EIE87881.1 - 9.7e-34 116.6 0.1 3.1e-22 78.9 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIE87881.1 - 1.1e-09 37.7 0.1 2.3e-05 23.6 0.0 3.1 1 1 1 2 2 2 2 Protein tyrosine kinase HECT_2 PF09814.4 EIE87882.1 - 9.4e-26 90.3 5.8 9.6e-25 87.0 1.8 2.0 1 1 1 2 2 2 2 HECT-like Ubiquitin-conjugating enzyme (E2)-binding GFA PF04828.9 EIE87882.1 - 0.0039 17.1 1.0 0.032 14.1 0.1 2.2 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme IGF2_C PF08365.6 EIE87884.1 - 0.36 10.6 3.7 0.73 9.6 2.6 1.5 1 0 0 1 1 1 0 Insulin-like growth factor II E-peptide Arm PF00514.18 EIE87885.1 - 1.8e-67 221.0 28.3 1.1e-11 44.1 0.1 10.5 10 0 0 10 10 10 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EIE87885.1 - 4.5e-26 90.9 16.2 1.5e-05 25.2 0.2 7.3 2 2 4 7 7 7 6 HEAT repeats HEAT PF02985.17 EIE87885.1 - 1.4e-15 55.8 17.1 0.045 13.8 0.0 9.4 9 0 0 9 9 9 4 HEAT repeat HEAT_EZ PF13513.1 EIE87885.1 - 1.8e-14 53.7 13.2 0.022 15.2 0.0 8.4 7 1 2 9 9 9 4 HEAT-like repeat Adaptin_N PF01602.15 EIE87885.1 - 1.4e-13 50.0 10.8 6.1e-11 41.3 1.2 2.4 1 1 1 2 2 2 2 Adaptin N terminal region Arm_2 PF04826.8 EIE87885.1 - 1.7e-11 43.7 7.7 0.00089 18.4 0.1 3.6 1 1 2 3 3 3 3 Armadillo-like KAP PF05804.7 EIE87885.1 - 2.9e-11 42.0 2.5 4.8e-11 41.3 1.6 1.4 1 1 0 1 1 1 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.9 EIE87885.1 - 1.6e-06 27.5 6.0 0.0049 16.0 3.0 3.2 1 1 2 3 3 3 3 V-ATPase subunit H Cnd1 PF12717.2 EIE87885.1 - 6.1e-06 26.2 5.7 0.0016 18.3 0.5 3.8 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_C PF11698.3 EIE87885.1 - 0.0001 22.2 6.6 0.53 10.2 0.3 5.5 2 2 4 6 6 6 1 V-ATPase subunit H DUF908 PF06012.7 EIE87885.1 - 0.0012 18.2 4.6 0.26 10.5 0.1 3.4 2 1 0 3 3 3 2 Domain of Unknown Function (DUF908) Vac14_Fab1_bd PF12755.2 EIE87885.1 - 0.002 18.4 0.6 7.5 7.0 0.0 4.0 2 1 2 4 4 4 1 Vacuolar 14 Fab1-binding region Ribosomal_S13_N PF08069.7 EIE87886.1 - 2.2e-31 107.4 0.2 5.1e-31 106.2 0.1 1.6 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 EIE87886.1 - 5.6e-25 86.9 0.3 1.1e-24 86.0 0.1 1.5 2 0 0 2 2 2 1 Ribosomal protein S15 Exo70 PF03081.10 EIE87889.1 - 1.3e-41 142.6 0.1 2e-41 142.0 0.1 1.3 1 0 0 1 1 1 1 Exo70 exocyst complex subunit GMC_oxred_N PF00732.14 EIE87890.1 - 3.3e-54 184.0 0.0 5.6e-54 183.2 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EIE87890.1 - 5.4e-32 111.0 0.0 8.8e-32 110.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase AAA PF00004.24 EIE87891.1 - 1e-97 323.4 0.0 1e-47 161.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 EIE87891.1 - 4.6e-20 71.3 1.7 3.2e-19 68.6 0.7 2.5 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.7 EIE87891.1 - 1.3e-14 53.8 0.0 2.7e-05 23.3 0.0 3.5 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 EIE87891.1 - 3.3e-13 49.9 0.0 2.6e-07 30.7 0.0 3.0 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 EIE87891.1 - 8.4e-13 48.4 0.0 3.6e-06 26.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EIE87891.1 - 2.3e-12 46.8 0.3 8.8e-06 25.4 0.0 4.0 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EIE87891.1 - 3.7e-12 47.1 0.1 0.0001 23.1 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.1 EIE87891.1 - 1.2e-11 44.8 0.1 0.0019 18.3 0.0 4.2 3 2 0 3 3 2 2 AAA domain AAA_16 PF13191.1 EIE87891.1 - 3.5e-10 40.1 0.0 0.002 18.1 0.0 3.5 3 2 1 4 4 3 2 AAA ATPase domain CDC48_2 PF02933.12 EIE87891.1 - 4.3e-10 39.0 0.0 9.3e-10 38.0 0.0 1.5 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 TIP49 PF06068.8 EIE87891.1 - 2e-09 36.6 0.7 0.00062 18.6 0.0 3.0 3 0 0 3 3 3 2 TIP49 C-terminus IstB_IS21 PF01695.12 EIE87891.1 - 2.2e-08 33.7 0.0 0.003 16.9 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein Zeta_toxin PF06414.7 EIE87891.1 - 5.6e-08 32.1 0.0 0.01 14.9 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin AAA_19 PF13245.1 EIE87891.1 - 7.7e-08 31.9 0.8 0.0094 15.6 0.0 2.9 2 0 0 2 2 2 2 Part of AAA domain AAA_18 PF13238.1 EIE87891.1 - 2.1e-07 31.3 0.0 0.034 14.4 0.0 3.0 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 EIE87891.1 - 2.6e-07 30.0 0.2 0.022 13.9 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 EIE87891.1 - 2.9e-07 30.4 0.0 0.0083 16.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 EIE87891.1 - 1.7e-06 28.1 0.0 0.016 15.3 0.0 3.0 2 0 0 2 2 2 2 RNA helicase ABC_tran PF00005.22 EIE87891.1 - 2e-06 28.1 0.0 0.028 14.7 0.0 3.7 3 1 0 3 3 2 2 ABC transporter AAA_28 PF13521.1 EIE87891.1 - 2.3e-06 27.6 0.0 0.11 12.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain ResIII PF04851.10 EIE87891.1 - 3.3e-06 27.0 0.0 0.0063 16.3 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Sigma54_activat PF00158.21 EIE87891.1 - 4.8e-06 26.1 0.0 0.17 11.3 0.0 3.3 2 1 0 2 2 2 2 Sigma-54 interaction domain Parvo_NS1 PF01057.12 EIE87891.1 - 5.2e-06 25.5 0.2 0.0094 14.8 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_25 PF13481.1 EIE87891.1 - 7.7e-06 25.4 8.9 0.019 14.3 0.0 4.3 3 2 2 5 5 4 2 AAA domain DUF815 PF05673.8 EIE87891.1 - 1.1e-05 24.4 0.0 0.0032 16.4 0.0 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF815) KaiC PF06745.8 EIE87891.1 - 2e-05 23.8 0.9 0.9 8.6 0.0 3.5 2 1 1 3 3 3 2 KaiC Vps4_C PF09336.5 EIE87891.1 - 2.2e-05 24.2 0.0 0.00027 20.7 0.0 2.7 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain PhoH PF02562.11 EIE87891.1 - 3e-05 23.3 0.2 0.21 10.7 0.0 2.6 2 0 0 2 2 2 2 PhoH-like protein AAA_24 PF13479.1 EIE87891.1 - 5.2e-05 22.9 0.1 0.11 12.1 0.0 3.1 3 0 0 3 3 3 1 AAA domain Sigma54_activ_2 PF14532.1 EIE87891.1 - 6.3e-05 23.0 0.0 0.3 11.1 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain Arch_ATPase PF01637.13 EIE87891.1 - 7.2e-05 22.5 0.0 2.1 7.9 0.1 3.4 2 1 1 3 3 3 2 Archaeal ATPase Bac_DnaA PF00308.13 EIE87891.1 - 9.8e-05 22.1 0.0 0.6 9.7 0.0 2.6 2 0 0 2 2 2 2 Bacterial dnaA protein AAA_11 PF13086.1 EIE87891.1 - 0.00016 21.3 0.0 0.29 10.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.4 EIE87891.1 - 0.00022 20.3 0.0 0.37 9.7 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_3 PF07726.6 EIE87891.1 - 0.00022 20.8 0.0 0.6 9.7 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EIE87891.1 - 0.00034 20.3 0.1 0.51 9.9 0.0 3.5 3 0 0 3 3 3 1 NACHT domain NB-ARC PF00931.17 EIE87891.1 - 0.0013 17.6 0.0 0.26 10.0 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain NTPase_1 PF03266.10 EIE87891.1 - 0.0022 17.7 2.3 1.2 8.8 0.0 4.3 4 0 0 4 4 4 1 NTPase AAA_30 PF13604.1 EIE87891.1 - 0.0037 16.8 0.0 1.4 8.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 EIE87891.1 - 0.0053 16.3 0.0 0.23 10.9 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase T2SE PF00437.15 EIE87891.1 - 0.0092 14.9 0.0 0.58 9.0 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein SKI PF01202.17 EIE87891.1 - 0.02 14.7 0.0 7.6 6.3 0.0 2.7 2 0 0 2 2 2 0 Shikimate kinase ATP-synt_ab PF00006.20 EIE87891.1 - 0.028 13.9 0.0 7.3 6.0 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_10 PF12846.2 EIE87891.1 - 0.029 13.7 1.5 5.2 6.4 0.0 3.8 3 1 1 4 4 4 0 AAA-like domain Cytidylate_kin2 PF13189.1 EIE87891.1 - 0.03 14.2 0.0 0.7 9.7 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase-like family UPF0079 PF02367.12 EIE87891.1 - 0.066 12.8 0.1 3.8 7.1 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 KTI12 PF08433.5 EIE87891.1 - 0.067 12.3 0.0 7.5 5.6 0.0 2.5 2 0 0 2 2 2 0 Chromatin associated protein KTI12 IPT PF01745.11 EIE87891.1 - 0.094 11.8 0.1 4.8 6.2 0.0 2.2 2 0 0 2 2 2 0 Isopentenyl transferase Zot PF05707.7 EIE87891.1 - 0.097 12.1 0.1 16 4.9 0.0 3.3 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_23 PF13476.1 EIE87891.1 - 0.15 12.4 1.0 4.1 7.6 0.0 2.8 2 1 0 2 2 2 0 AAA domain Torsin PF06309.6 EIE87891.1 - 0.25 11.2 0.0 17 5.3 0.0 2.5 2 0 0 2 2 2 0 Torsin MobB PF03205.9 EIE87891.1 - 0.27 10.9 2.2 9.3 5.9 0.0 3.7 4 0 0 4 4 4 0 Molybdopterin guanine dinucleotide synthesis protein B Arc_PepC PF06819.6 EIE87892.1 - 0.066 13.1 0.8 0.63 9.9 0.0 2.2 1 1 1 2 2 2 0 Archaeal Peptidase A24 C-terminal Domain Med2 PF11214.3 EIE87892.1 - 2.4 8.2 8.2 2.2 8.3 2.8 2.6 1 1 2 3 3 3 0 Mediator complex subunit 2 Ribosomal_S21e PF01249.13 EIE87893.1 - 1.2e-39 134.0 0.0 1.3e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e Ribosomal_L31e PF01198.14 EIE87894.1 - 6.4e-15 54.6 1.3 7.8e-15 54.3 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e F_actin_cap_B PF01115.12 EIE87895.1 - 5.1e-107 356.5 0.1 6.2e-107 356.2 0.0 1.1 1 0 0 1 1 1 1 F-actin capping protein, beta subunit F-actin_cap_A PF01267.12 EIE87895.1 - 0.00026 20.1 0.1 0.00086 18.4 0.0 2.0 1 1 0 1 1 1 1 F-actin capping protein alpha subunit UBN2 PF14223.1 EIE87895.1 - 0.0081 15.9 0.2 0.057 13.1 0.0 2.2 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type Lectin_leg-like PF03388.8 EIE87896.1 - 1.7e-68 230.1 0.1 2.1e-68 229.9 0.0 1.0 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.14 EIE87896.1 - 3.2e-06 26.6 0.0 2.1e-05 24.0 0.0 1.9 1 1 0 1 1 1 1 Legume lectin domain WD40 PF00400.27 EIE87898.1 - 6.5e-13 48.0 0.4 4.6e-08 32.6 0.0 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 EIE87898.1 - 0.0037 15.4 0.0 0.0048 15.0 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 ECR1_N PF14382.1 EIE87899.1 - 1e-12 47.1 0.3 1.9e-12 46.2 0.2 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region RnfC_N PF13375.1 EIE87899.1 - 0.039 13.6 0.1 0.076 12.7 0.1 1.6 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain EXOSC1 PF10447.4 EIE87899.1 - 0.04 13.8 0.3 0.77 9.7 0.2 2.3 1 1 0 1 1 1 0 Exosome component EXOSC1/CSL4 UDPGT PF00201.13 EIE87900.1 - 1.6e-09 36.8 0.0 4.1e-09 35.5 0.0 1.6 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_transf_28 PF03033.15 EIE87900.1 - 0.00086 19.0 0.0 0.0016 18.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain SDA1 PF05285.7 EIE87901.1 - 0.022 14.0 1.6 0.03 13.6 1.1 1.1 1 0 0 1 1 1 0 SDA1 DUF4611 PF15387.1 EIE87901.1 - 0.059 13.5 4.2 2.5 8.2 3.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) PBP1_TM PF14812.1 EIE87901.1 - 0.84 9.9 6.2 1.3 9.3 1.4 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sigma70_ner PF04546.8 EIE87901.1 - 2.4 7.7 11.9 8.9 5.8 6.3 2.6 2 1 0 2 2 2 0 Sigma-70, non-essential region CENP-B_dimeris PF09026.5 EIE87901.1 - 2.7 8.2 8.3 0.19 12.0 0.9 2.1 2 0 0 2 2 2 0 Centromere protein B dimerisation domain NUP50 PF08911.6 EIE87901.1 - 4.4 7.7 6.5 0.41 11.0 1.0 1.9 2 0 0 2 2 2 0 NUP50 (Nucleoporin 50 kDa) Mis12 PF05859.7 EIE87902.1 - 0.12 12.2 0.8 4.2 7.1 0.3 2.1 2 0 0 2 2 2 0 Mis12 protein RPA_interact_C PF14768.1 EIE87904.1 - 2.5e-05 24.5 8.8 6.1e-05 23.3 4.8 2.4 1 1 2 3 3 3 1 Replication protein A interacting C-terminal A2L_zn_ribbon PF08792.5 EIE87904.1 - 0.0023 17.3 0.9 0.0063 15.9 0.6 1.7 1 0 0 1 1 1 1 A2L zinc ribbon domain Zn_Tnp_IS91 PF14319.1 EIE87904.1 - 0.01 15.3 4.0 0.01 15.3 2.8 2.4 2 1 1 3 3 3 0 Transposase zinc-binding domain Gluconate_2-dh3 PF13618.1 EIE87904.1 - 0.057 13.5 0.4 0.067 13.3 0.3 1.3 1 1 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 DNA_RNApol_7kD PF03604.8 EIE87904.1 - 0.087 12.3 0.4 0.26 10.7 0.2 1.8 1 0 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit HypA PF01155.14 EIE87904.1 - 0.15 11.7 4.7 0.048 13.3 1.5 1.6 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-CHY PF05495.7 EIE87904.1 - 0.16 12.1 6.3 0.18 11.9 1.0 2.3 2 0 0 2 2 2 0 CHY zinc finger eIF-5_eIF-2B PF01873.12 EIE87904.1 - 0.36 10.5 3.9 0.12 11.9 0.8 1.7 2 0 0 2 2 2 0 Domain found in IF2B/IF5 zf-RING_4 PF14570.1 EIE87904.1 - 1.9 8.1 5.8 26 4.4 4.0 2.3 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF1451 PF07295.6 EIE87904.1 - 2.6 7.7 10.4 0.38 10.5 1.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1451) PHD PF00628.24 EIE87904.1 - 6 6.6 8.0 3.1 7.5 2.8 2.3 2 0 0 2 2 2 0 PHD-finger DZR PF12773.2 EIE87904.1 - 6.3 6.6 7.2 26 4.7 5.0 2.2 1 1 0 1 1 1 0 Double zinc ribbon Kinetochor_Ybp2 PF08568.5 EIE87905.1 - 4.5e-16 58.2 0.1 4.5e-16 58.2 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin Pho86 PF11124.3 EIE87905.1 - 0.056 12.4 0.0 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 Inorganic phosphate transporter Pho86 Ribosomal_60s PF00428.14 EIE87906.1 - 7.3e-26 90.3 9.7 8.8e-26 90.1 6.7 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF4349 PF14257.1 EIE87906.1 - 3.6 6.7 5.5 19 4.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) WD40 PF00400.27 EIE87907.1 - 1.3e-72 237.3 17.3 2.2e-08 33.6 0.3 11.1 11 0 0 11 11 11 10 WD domain, G-beta repeat Utp12 PF04003.7 EIE87907.1 - 2.7e-21 75.5 0.4 5e-21 74.6 0.3 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family Nucleoporin_N PF08801.6 EIE87907.1 - 0.00024 19.9 5.8 3.7 6.2 0.0 5.8 2 2 3 6 6 6 3 Nup133 N terminal like Nup160 PF11715.3 EIE87907.1 - 0.036 12.2 10.6 0.68 7.9 0.2 5.3 4 3 1 6 6 6 0 Nucleoporin Nup120/160 APG5 PF04106.7 EIE87908.1 - 7.2e-41 139.8 0.8 9e-41 139.5 0.5 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 WD40 PF00400.27 EIE87909.1 - 4.4e-37 124.6 12.0 5.4e-11 41.9 0.2 6.4 5 1 1 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 EIE87909.1 - 0.039 12.0 0.9 0.31 9.1 0.6 2.4 1 1 1 2 2 2 0 Nucleoporin Nup120/160 DUF1754 PF08555.5 EIE87909.1 - 1 10.0 10.9 2.3 8.8 7.6 1.5 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) WD40 PF00400.27 EIE87910.1 - 4.7e-22 76.9 5.9 2.4e-05 24.0 0.0 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat Ammonium_transp PF00909.16 EIE87911.1 - 5.4e-124 413.6 26.9 6.1e-124 413.5 18.7 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family CLTH PF10607.4 EIE87912.1 - 1.5e-29 102.5 0.1 2.4e-29 101.9 0.1 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.23 EIE87912.1 - 3.6e-27 94.8 0.5 6.3e-27 94.1 0.3 1.4 1 0 0 1 1 1 1 SPRY domain LisH PF08513.6 EIE87912.1 - 2.9e-05 23.6 0.1 8.9e-05 22.1 0.0 1.9 1 0 0 1 1 1 1 LisH Ribosomal_S10 PF00338.17 EIE87913.1 - 1.5e-29 101.6 0.0 3.5e-29 100.5 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein S10p/S20e Ribosomal_S9 PF00380.14 EIE87914.1 - 2.7e-35 121.2 0.2 3.1e-35 121.0 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 14-3-3 PF00244.15 EIE87915.1 - 1.8e-113 377.4 6.7 2.1e-113 377.2 4.7 1.0 1 0 0 1 1 1 1 14-3-3 protein Imm7 PF15588.1 EIE87915.1 - 0.042 13.8 0.2 0.34 10.9 0.0 2.2 2 0 0 2 2 2 0 Immunity protein 7 DUF327 PF03885.8 EIE87915.1 - 0.081 12.7 1.4 0.22 11.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF327) MFS_1 PF07690.11 EIE87916.1 - 1.3e-28 99.7 37.7 1.3e-28 99.7 26.1 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIE87916.1 - 1.2e-10 40.5 5.1 1.2e-10 40.5 3.5 3.6 3 1 1 4 4 4 1 Sugar (and other) transporter TRI12 PF06609.8 EIE87916.1 - 4.7e-05 21.7 20.2 4.7e-05 21.7 14.0 2.5 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF4064 PF13273.1 EIE87916.1 - 0.25 11.4 0.1 0.25 11.4 0.1 4.8 3 2 3 6 6 6 0 Protein of unknown function (DUF4064) Gemini_C4 PF01492.12 EIE87917.1 - 0.018 14.7 0.3 0.043 13.5 0.1 1.6 2 0 0 2 2 2 0 Geminivirus C4 protein Guanylate_cyc PF00211.15 EIE87919.1 - 0.1 11.9 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Adenylate and Guanylate cyclase catalytic domain RTC_insert PF05189.8 EIE87920.1 - 1.6e-34 118.0 0.0 2.3e-34 117.4 0.0 1.2 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain RTC PF01137.16 EIE87920.1 - 5.1e-32 110.5 0.0 5.7e-32 110.3 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase LSM PF01423.17 EIE87921.1 - 6.9e-14 51.1 0.2 9.3e-14 50.7 0.1 1.2 1 0 0 1 1 1 1 LSM domain Septin PF00735.13 EIE87922.1 - 2.8e-15 56.0 8.2 1.7e-12 46.9 1.4 3.4 1 1 1 2 2 2 2 Septin Miro PF08477.8 EIE87922.1 - 9.9e-05 22.8 2.3 0.00058 20.3 0.1 2.9 2 2 1 3 3 3 1 Miro-like protein SR-25 PF10500.4 EIE87922.1 - 0.0016 17.9 10.2 0.0026 17.2 7.0 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF258 PF03193.11 EIE87922.1 - 0.0034 16.5 0.4 0.0095 15.1 0.3 1.9 1 1 0 1 1 1 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EIE87922.1 - 0.006 16.5 0.0 0.022 14.7 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.1 EIE87922.1 - 0.0065 15.9 0.1 0.015 14.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.1 EIE87922.1 - 0.016 15.5 9.3 0.078 13.2 6.4 1.9 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EIE87922.1 - 0.018 15.0 0.1 0.049 13.6 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_21 PF13304.1 EIE87922.1 - 0.028 14.3 0.1 0.32 10.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EIE87922.1 - 0.037 13.6 0.0 0.17 11.4 0.0 2.1 2 0 0 2 2 2 0 NACHT domain IstB_IS21 PF01695.12 EIE87922.1 - 0.037 13.4 0.0 0.15 11.5 0.0 2.0 1 0 0 1 1 1 0 IstB-like ATP binding protein ABC_tran PF00005.22 EIE87922.1 - 0.062 13.5 2.5 0.32 11.2 0.0 2.6 2 1 0 2 2 2 0 ABC transporter AAA_22 PF13401.1 EIE87922.1 - 0.071 13.2 0.3 0.25 11.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain Phe_tRNA-synt_N PF02912.13 EIE87922.1 - 0.33 10.7 3.9 0.56 9.9 0.3 2.7 3 0 0 3 3 3 0 Aminoacyl tRNA synthetase class II, N-terminal domain DUF3759 PF12585.3 EIE87923.1 - 5.8e-15 54.9 1.8 1.6e-14 53.5 1.2 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) RicinB_lectin_2 PF14200.1 EIE87923.1 - 9.2e-05 22.7 0.0 0.66 10.3 0.0 2.8 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 EIE87923.1 - 9.4e-05 22.4 0.0 0.5 10.4 0.0 2.8 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain NMN_transporter PF04973.7 EIE87923.1 - 0.016 14.7 0.1 0.028 13.8 0.1 1.3 1 0 0 1 1 1 0 Nicotinamide mononucleotide transporter RskA PF10099.4 EIE87923.1 - 0.15 11.7 0.0 1.6 8.4 0.0 2.4 3 0 0 3 3 3 0 Anti-sigma-K factor rskA zf-MYND PF01753.13 EIE87924.1 - 0.00011 22.0 23.8 0.00011 22.0 16.5 2.2 2 1 0 2 2 2 1 MYND finger Sporozoite_P67 PF05642.6 EIE87924.1 - 0.013 13.4 2.9 0.014 13.2 2.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Clathrin-link PF09268.5 EIE87924.1 - 0.025 13.6 0.2 0.051 12.6 0.1 1.5 1 0 0 1 1 1 0 Clathrin, heavy-chain linker Wbp11 PF09429.5 EIE87924.1 - 0.049 13.6 0.6 0.09 12.7 0.4 1.4 1 0 0 1 1 1 0 WW domain binding protein 11 Rota_NS26 PF01525.11 EIE87924.1 - 0.085 12.6 1.6 0.23 11.2 0.0 2.1 2 0 0 2 2 2 0 Rotavirus NS26 MGC-24 PF05283.6 EIE87924.1 - 0.2 11.4 13.6 0.36 10.5 9.4 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) Mucin PF01456.12 EIE87924.1 - 0.26 11.0 18.9 0.44 10.3 13.1 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF3439 PF11921.3 EIE87924.1 - 2 8.1 12.5 5.2 6.8 8.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) WD40 PF00400.27 EIE87926.1 - 2.6e-67 220.4 24.9 5.8e-10 38.6 0.4 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.2 EIE87926.1 - 3e-14 52.4 0.1 6.8e-14 51.3 0.1 1.6 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 EIE87926.1 - 3.7e-14 51.7 16.6 0.0065 14.6 0.1 6.1 2 1 3 5 5 5 5 Nucleoporin Nup120/160 F-box PF00646.28 EIE87926.1 - 3.1e-07 29.8 0.0 9.2e-07 28.3 0.0 1.8 1 0 0 1 1 1 1 F-box domain BBS2_Mid PF14783.1 EIE87926.1 - 0.00026 20.7 0.0 1.1 8.9 0.0 4.3 2 1 1 4 4 4 1 Ciliary BBSome complex subunit 2, middle region PQQ_2 PF13360.1 EIE87926.1 - 0.01 15.3 0.2 2.4 7.5 0.1 3.2 1 1 2 3 3 3 1 PQQ-like domain LIM_bind PF01803.11 EIE87926.1 - 0.046 12.8 0.0 0.15 11.1 0.0 1.8 1 1 1 2 2 2 0 LIM-domain binding protein Phosphodiest PF01663.17 EIE87927.1 - 1.5e-12 47.5 0.8 2.1e-12 47.0 0.6 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EIE87927.1 - 4.9e-05 22.6 0.2 7.7e-05 22.0 0.1 1.3 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 EIE87927.1 - 0.00014 21.3 0.4 0.00023 20.6 0.3 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily DUF3040 PF11239.3 EIE87927.1 - 0.032 14.2 1.5 0.16 12.0 0.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3040) RNA_pol_Rpb5_C PF01191.14 EIE87928.1 - 5.7e-37 125.1 0.7 1.1e-36 124.2 0.5 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 EIE87928.1 - 4.2e-20 71.9 0.0 8.9e-20 70.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Ribosomal_L39 PF00832.15 EIE87930.1 - 3.1e-19 68.1 12.5 3.5e-19 67.9 8.7 1.0 1 0 0 1 1 1 1 Ribosomal L39 protein DUF1418 PF07214.7 EIE87931.1 - 9.6 5.9 10.4 1.7 8.3 4.5 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1418) eIF3g PF12353.3 EIE87932.1 - 2.9e-43 146.8 5.1 4.9e-43 146.0 3.5 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 EIE87932.1 - 2.3e-19 68.7 0.1 6.7e-19 67.3 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE87932.1 - 3.3e-14 52.5 0.0 1e-13 51.0 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE87932.1 - 4e-12 45.7 0.1 7.7e-11 41.6 0.1 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.6 EIE87932.1 - 0.042 13.8 0.0 0.1 12.6 0.0 1.7 1 0 0 1 1 1 0 RNA binding domain NSP11 PF06471.7 EIE87932.1 - 0.052 11.7 0.0 0.064 11.4 0.0 1.1 1 0 0 1 1 1 0 NSP11 DUF2782 PF11191.3 EIE87932.1 - 0.11 12.5 0.2 0.22 11.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2782) eIF3_subunit PF08597.5 EIE87932.1 - 0.22 11.0 9.9 0.066 12.7 2.5 2.2 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit Asp_protease PF09668.5 EIE87933.1 - 8.8e-51 170.6 0.0 1.6e-50 169.8 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease ubiquitin PF00240.18 EIE87933.1 - 1e-10 40.8 0.0 2e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Asp_protease_2 PF13650.1 EIE87933.1 - 5.2e-10 39.6 0.1 1.3e-09 38.4 0.0 1.7 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.1 EIE87933.1 - 7.9e-08 32.0 0.0 1.8e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease XPC-binding PF09280.6 EIE87933.1 - 5e-07 29.0 1.7 1e-06 28.0 0.5 2.1 2 0 0 2 2 2 1 XPC-binding domain RVP PF00077.15 EIE87933.1 - 4.4e-05 23.3 0.0 0.0001 22.1 0.0 1.6 1 1 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.6 EIE87933.1 - 0.00014 21.8 0.0 0.00023 21.0 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Caps_assemb_Wzi PF14052.1 EIE87933.1 - 0.071 11.9 0.1 0.095 11.5 0.1 1.1 1 0 0 1 1 1 0 Capsule assembly protein Wzi Transposase_21 PF02992.9 EIE87935.1 - 4.1e-21 75.1 0.1 7.7e-21 74.2 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 DUF1258 PF06869.7 EIE87935.1 - 0.0061 15.6 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) Mod_r PF07200.8 EIE87936.1 - 0.0005 20.0 0.8 0.00056 19.8 0.6 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Matrilin_ccoil PF10393.4 EIE87936.1 - 0.0041 16.4 0.3 0.0073 15.6 0.2 1.4 1 0 0 1 1 1 1 Trimeric coiled-coil oligomerisation domain of matrilin bZIP_1 PF00170.16 EIE87936.1 - 0.38 10.7 2.9 0.49 10.3 1.6 1.5 1 1 0 1 1 1 0 bZIP transcription factor TC1 PF15063.1 EIE87938.1 - 0.038 13.5 0.0 0.063 12.8 0.0 1.4 1 0 0 1 1 1 0 Thyroid cancer protein 1 RVT_1 PF00078.22 EIE87939.1 - 2.4e-14 53.2 0.9 6.7e-14 51.7 0.6 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 EIE87939.1 - 0.00013 22.3 0.1 0.0003 21.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 EIE87939.1 - 0.00032 20.5 0.1 0.0014 18.5 0.0 2.2 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EIE87939.1 - 0.051 13.3 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease rve PF00665.21 EIE87940.1 - 6.6e-09 35.9 0.0 1.1e-08 35.2 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain YcgR_2 PF12945.2 EIE87940.1 - 0.01 15.6 0.0 0.021 14.6 0.0 1.6 1 0 0 1 1 1 0 Flagellar protein YcgR HTH_Tnp_Tc3_2 PF01498.13 EIE87941.1 - 2.3e-19 69.2 1.9 2.5e-19 69.1 0.5 1.7 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 EIE87941.1 - 3.5e-05 23.9 0.3 6.5e-05 23.0 0.2 1.4 1 0 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.1 EIE87941.1 - 0.00011 22.9 0.8 0.00045 20.9 0.1 2.1 2 0 0 2 2 2 1 Homeodomain-like domain NUMOD3 PF07460.6 EIE87941.1 - 0.029 14.2 0.1 0.31 10.9 0.1 2.2 2 0 0 2 2 2 0 NUMOD3 motif (2 copies) HTH_21 PF13276.1 EIE87941.1 - 0.047 13.7 0.2 0.35 10.9 0.0 2.4 2 1 2 4 4 4 0 HTH-like domain HTH_Tnp_Tc3_2 PF01498.13 EIE87942.1 - 2.4e-06 27.4 3.3 1.3e-05 25.1 1.8 2.6 3 1 0 3 3 3 1 Transposase HTH_29 PF13551.1 EIE87942.1 - 9.4e-05 22.5 0.0 0.0075 16.4 0.0 2.2 2 0 0 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.1 EIE87942.1 - 0.00091 18.7 0.0 0.0034 16.9 0.0 1.9 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Crp_2 PF13545.1 EIE87942.1 - 0.025 14.3 0.0 0.072 12.8 0.0 1.8 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_30 PF13556.1 EIE87942.1 - 0.12 11.9 0.0 0.28 10.7 0.0 1.6 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.13 EIE87943.1 - 2.6e-07 30.5 1.5 5.4e-07 29.5 0.7 1.8 1 1 1 2 2 2 1 Transposase MRL1 PF13003.2 EIE87944.1 - 0.029 14.1 0.0 0.036 13.9 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L1 DUF1759 PF03564.10 EIE87946.1 - 0.0014 18.4 0.2 0.0014 18.4 0.2 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF1759) YlbE PF14003.1 EIE87946.1 - 0.014 15.4 0.2 1.9 8.6 0.0 2.6 2 0 0 2 2 2 0 YlbE-like protein HTH_Tnp_Tc3_2 PF01498.13 EIE87947.1 - 3.3e-09 36.6 0.5 6.9e-09 35.6 0.3 1.6 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.1 EIE87947.1 - 2.3e-05 24.4 0.2 3.5e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EIE87947.1 - 0.00011 21.6 0.4 0.0014 18.2 0.0 2.1 2 0 0 2 2 2 1 Homeodomain-like domain HTH_7 PF02796.10 EIE87947.1 - 0.012 15.4 0.1 0.012 15.4 0.1 2.3 3 0 0 3 3 3 0 Helix-turn-helix domain of resolvase DUF2110 PF09883.4 EIE87947.1 - 0.026 14.1 0.1 0.033 13.8 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2110) HTH_Tnp_IS630 PF01710.11 EIE87947.1 - 0.049 13.2 0.1 0.074 12.7 0.1 1.5 1 1 0 1 1 1 0 Transposase HTH_28 PF13518.1 EIE87947.1 - 0.08 12.9 0.2 0.46 10.5 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain Spore_YhcN_YlaJ PF09580.5 EIE87947.1 - 0.091 12.8 1.1 0.11 12.5 0.8 1.1 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) HTH_38 PF13936.1 EIE87947.1 - 0.24 10.9 1.5 7.2 6.2 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain DDE_3 PF13358.1 EIE87948.1 - 2.9e-16 59.5 0.0 4.1e-16 59.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE87948.1 - 0.00016 21.7 0.0 0.00031 20.8 0.0 1.7 1 1 0 1 1 1 1 Integrase core domain DDE_3 PF13358.1 EIE87952.1 - 7.2e-18 64.7 0.1 1.3e-17 63.9 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE87952.1 - 1e-05 25.4 3.0 3.8e-05 23.6 1.8 2.3 2 1 0 2 2 2 1 Transposase HTH_29 PF13551.1 EIE87952.1 - 0.00064 19.8 0.1 0.001 19.2 0.1 1.3 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EIE87952.1 - 0.0012 18.4 0.0 0.0033 17.0 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_30 PF13556.1 EIE87952.1 - 0.0082 15.7 0.0 0.14 11.7 0.0 2.2 2 0 0 2 2 2 1 PucR C-terminal helix-turn-helix domain HTH_7 PF02796.10 EIE87952.1 - 0.0082 15.9 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_38 PF13936.1 EIE87952.1 - 0.023 14.2 0.0 0.088 12.3 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Crp_2 PF13545.1 EIE87952.1 - 0.16 11.7 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain DDE_3 PF13358.1 EIE87953.1 - 2.7e-11 43.4 0.0 4.8e-11 42.5 0.0 1.4 1 1 0 1 1 1 1 DDE superfamily endonuclease DUF569 PF04601.8 EIE87954.1 - 0.0046 16.3 0.2 0.018 14.4 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF569) HTH_12 PF08461.5 EIE87954.1 - 0.026 14.2 0.0 0.048 13.4 0.0 1.4 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain HTH_26 PF13443.1 EIE87954.1 - 0.12 12.5 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain DDE_3 PF13358.1 EIE87955.1 - 7.5e-22 77.6 0.3 1.7e-21 76.4 0.1 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_Tnp_IS1595 PF12762.2 EIE87955.1 - 1.3e-07 31.5 0.7 4.8e-06 26.4 0.0 2.7 3 0 0 3 3 3 1 ISXO2-like transposase domain rve PF00665.21 EIE87955.1 - 0.0051 16.8 0.0 0.022 14.8 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain HMG_box_2 PF09011.5 EIE87955.1 - 0.035 14.4 0.3 0.079 13.3 0.2 1.6 1 0 0 1 1 1 0 HMG-box domain Proteasom_Rpn13 PF04683.8 EIE87955.1 - 0.074 13.1 0.5 0.56 10.3 0.1 2.3 2 0 0 2 2 2 0 Proteasome complex subunit Rpn13 ubiquitin receptor DUF2827 PF10933.3 EIE87955.1 - 0.081 11.3 0.0 0.12 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2827) Mod_r PF07200.8 EIE87957.1 - 0.039 13.8 0.1 0.079 12.8 0.0 1.4 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein DUF904 PF06005.7 EIE87957.1 - 0.078 13.2 0.5 0.16 12.2 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DivIC PF04977.10 EIE87957.1 - 0.23 10.9 1.0 0.49 9.9 0.7 1.4 1 0 0 1 1 1 0 Septum formation initiator RVT_1 PF00078.22 EIE87958.1 - 1.4e-28 99.7 0.0 2.3e-28 99.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EIE87958.1 - 1.3e-18 66.7 0.0 2.6e-18 65.7 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EIE87958.1 - 6.3e-05 23.0 0.2 0.00014 21.8 0.0 1.6 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family DDE_3 PF13358.1 EIE87959.1 - 3.8e-14 52.6 0.0 6.1e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF2567 PF10821.3 EIE87959.1 - 0.15 11.5 0.0 0.2 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2567) DDE_3 PF13358.1 EIE87961.1 - 2.5e-12 46.7 0.6 6.7e-12 45.3 0.3 1.7 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE87961.1 - 5.8e-08 32.6 3.8 6e-08 32.6 0.1 2.4 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 EIE87961.1 - 0.00088 19.4 1.5 0.0026 17.8 1.0 1.8 1 1 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_ISL3 PF13542.1 EIE87961.1 - 0.036 13.2 0.8 0.036 13.2 0.5 2.5 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 rve PF00665.21 EIE87961.1 - 0.082 13.0 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain HTH_12 PF08461.5 EIE87961.1 - 0.096 12.4 0.1 0.3 10.8 0.1 1.8 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain HTH_23 PF13384.1 EIE87961.1 - 0.26 11.0 2.9 2.8 7.7 0.2 2.6 2 0 0 2 2 2 0 Homeodomain-like domain HTH_21 PF13276.1 EIE87961.1 - 0.34 10.9 3.6 0.98 9.4 0.0 2.7 3 0 0 3 3 3 0 HTH-like domain NFRKB_winged PF14465.1 EIE87961.1 - 0.34 10.7 3.1 5.8 6.8 0.5 2.9 2 1 1 3 3 3 0 NFRKB Winged Helix-like HTH_32 PF13565.1 EIE87961.1 - 0.87 10.4 4.2 0.63 10.8 0.5 2.6 4 0 0 4 4 4 0 Homeodomain-like domain DUF1033 PF06279.6 EIE87961.1 - 1.4 8.7 6.4 0.34 10.7 0.1 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF1033) rve PF00665.21 EIE87962.1 - 1.3e-24 86.5 0.0 4.6e-24 84.8 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 EIE87962.1 - 4.7e-16 58.7 0.0 9.5e-16 57.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE87962.1 - 7.9e-11 41.4 0.6 2.1e-10 40.0 0.4 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 EIE87962.1 - 0.00029 20.1 0.1 0.00087 18.6 0.1 1.9 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger rve_3 PF13683.1 EIE87962.1 - 0.026 14.0 0.0 0.072 12.6 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain DDE_Tnp_4 PF13359.1 EIE87963.1 - 0.0015 18.1 0.0 0.0018 17.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EIE87965.1 - 1.5e-11 44.2 0.3 2.1e-11 43.7 0.2 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE87966.1 - 1.7e-24 86.1 0.0 5.6e-24 84.5 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE87966.1 - 6.5e-16 58.3 0.0 1.3e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE87966.1 - 3.5e-09 36.2 0.3 1e-08 34.7 0.2 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 EIE87966.1 - 0.0004 19.7 0.1 0.001 18.4 0.1 1.8 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger rve_3 PF13683.1 EIE87966.1 - 0.027 14.0 0.0 0.086 12.3 0.0 1.9 1 0 0 1 1 1 0 Integrase core domain UBN2 PF14223.1 EIE87966.1 - 0.04 13.6 0.4 0.16 11.7 0.1 2.1 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 EIE87966.1 - 0.079 12.5 1.0 0.33 10.5 0.0 2.5 3 0 0 3 3 3 0 gag-polypeptide of LTR copia-type HTH_Tnp_Tc3_2 PF01498.13 EIE87967.1 - 1.4e-11 44.2 0.3 3.5e-11 42.9 0.2 1.7 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.1 EIE87967.1 - 0.0001 22.4 0.5 0.00017 21.6 0.3 1.4 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EIE87967.1 - 0.00022 20.7 0.2 0.0026 17.3 0.0 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_7 PF02796.10 EIE87967.1 - 0.001 18.9 0.3 0.065 13.1 0.0 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase rve PF00665.21 EIE87968.1 - 3.8e-19 68.9 0.0 5.4e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 EIE87969.1 - 1.7e-14 53.2 2.2 3e-14 52.4 1.5 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AhpC-TSA PF00578.16 EIE87971.1 - 1.7e-37 127.8 0.0 2.4e-37 127.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EIE87971.1 - 5e-15 55.3 0.0 6.8e-15 54.8 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 EIE87971.1 - 4.1e-13 48.7 0.1 9.5e-13 47.5 0.0 1.7 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin AhpC-TSA_2 PF13911.1 EIE87971.1 - 0.064 13.1 0.0 0.19 11.6 0.0 1.7 1 1 0 1 1 1 0 AhpC/TSA antioxidant enzyme 4HBT_2 PF13279.1 EIE87972.1 - 6e-10 39.6 0.2 9e-10 39.0 0.1 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.12 EIE87972.1 - 0.0048 15.8 0.1 0.0071 15.3 0.1 1.3 1 0 0 1 1 1 1 Acyl-ACP thioesterase ATP-synt_ab PF00006.20 EIE87973.1 - 4.9e-62 209.2 0.0 7e-62 208.7 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EIE87973.1 - 1.1e-16 61.3 0.2 2.4e-16 60.2 0.1 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain Exosortase_EpsH PF09721.5 EIE87974.1 - 0.055 12.6 0.9 0.072 12.2 0.6 1.1 1 0 0 1 1 1 0 Transmembrane exosortase (Exosortase_EpsH) DDE_3 PF13358.1 EIE87975.1 - 3.6e-09 36.5 0.0 4.9e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_IS1595 PF12762.2 EIE87976.1 - 9e-24 84.0 0.6 1.2e-23 83.6 0.4 1.1 1 0 0 1 1 1 1 ISXO2-like transposase domain DDE_Tnp_IS66 PF03050.9 EIE87976.1 - 0.043 13.0 0.1 0.057 12.6 0.1 1.2 1 0 0 1 1 1 0 Transposase IS66 family Arrestin_C PF02752.17 EIE87977.1 - 0.016 15.2 1.6 0.066 13.3 0.0 2.6 2 1 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain Homeobox PF00046.24 EIE87978.1 - 2e-21 75.3 1.1 5.6e-21 73.9 0.7 1.8 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EIE87978.1 - 1.5 8.6 4.2 0.37 10.5 0.2 2.1 2 0 0 2 2 2 0 Homeobox KN domain HMG_box PF00505.14 EIE87979.1 - 2.9e-19 69.1 1.2 5.6e-19 68.1 0.9 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EIE87979.1 - 2.1e-09 37.6 0.2 4.3e-09 36.6 0.2 1.5 1 0 0 1 1 1 1 HMG-box domain DDE_3 PF13358.1 EIE87981.1 - 8e-19 67.8 0.0 9.3e-19 67.6 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.14 EIE87981.1 - 0.026 13.6 0.0 0.029 13.5 0.0 1.0 1 0 0 1 1 1 0 DDE superfamily endonuclease rve PF00665.21 EIE87981.1 - 0.056 13.5 0.0 0.064 13.3 0.0 1.1 1 0 0 1 1 1 0 Integrase core domain LRRNT_2 PF08263.7 EIE87984.1 - 0.26 11.2 3.2 0.3 11.0 1.8 1.5 1 1 0 1 1 1 0 Leucine rich repeat N-terminal domain Plasmodium_Vir PF05795.6 EIE87986.1 - 0.21 10.7 9.6 0.014 14.6 1.7 2.1 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Dehydratase_SU PF02287.10 EIE87987.1 - 0.0079 15.9 2.8 0.33 10.6 0.1 2.4 1 1 1 2 2 2 2 Dehydratase small subunit YMF19 PF02326.10 EIE87987.1 - 1.1 9.8 6.5 0.48 11.0 1.4 2.5 1 1 1 2 2 2 0 Plant ATP synthase F0 WSN PF02206.13 EIE87987.1 - 1.5 8.6 5.8 0.55 10.0 0.6 2.6 3 1 0 3 3 3 0 Domain of unknown function Vir_act_alpha_C PF10400.4 EIE87987.1 - 2.1 8.7 10.2 2.3 8.6 0.4 2.9 2 1 1 3 3 3 0 Virulence activator alpha C-term DUF4367 PF14285.1 EIE87987.1 - 5.8 6.2 9.5 1.2 8.3 3.7 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4367) DUF1040 PF06288.8 EIE87987.1 - 7.7 6.8 7.9 1.6 9.0 1.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1040) Sec2p PF06428.6 EIE87988.1 - 9.5e-09 35.0 10.0 9.5e-09 35.0 6.9 2.5 1 1 1 2 2 2 1 GDP/GTP exchange factor Sec2p V_ATPase_I PF01496.14 EIE87988.1 - 2.5 5.8 9.2 3.3 5.4 6.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Matrilin_ccoil PF10393.4 EIE87988.1 - 7.2 6.0 9.8 20 4.6 0.1 2.7 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin AMP-binding PF00501.23 EIE87990.1 - 1.5e-96 323.3 0.0 1.9e-96 323.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EIE87990.1 - 6.7e-05 23.7 0.0 0.0021 18.9 0.0 2.9 2 1 1 3 3 3 1 AMP-binding enzyme C-terminal domain TPR_1 PF00515.23 EIE87992.1 - 2.6e-51 169.2 32.2 3.9e-09 35.7 0.0 10.7 11 1 0 11 11 11 8 Tetratricopeptide repeat TPR_2 PF07719.12 EIE87992.1 - 3.4e-45 148.3 30.5 1.5e-06 27.6 0.0 9.8 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_11 PF13414.1 EIE87992.1 - 4.8e-45 151.0 24.6 1.8e-13 49.9 0.2 6.7 4 2 3 7 7 7 6 TPR repeat TPR_16 PF13432.1 EIE87992.1 - 7.2e-33 112.5 10.0 5.4e-09 36.4 0.0 6.5 3 1 3 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.1 EIE87992.1 - 9e-33 109.5 31.5 4.7e-05 22.8 1.3 9.1 7 1 2 9 9 9 8 Tetratricopeptide repeat TPR_17 PF13431.1 EIE87992.1 - 2.5e-32 108.3 21.6 1.2e-05 25.0 0.1 10.6 11 0 0 11 11 10 6 Tetratricopeptide repeat TPR_12 PF13424.1 EIE87992.1 - 1.8e-28 98.2 22.8 2.2e-06 27.5 1.5 6.7 2 2 5 7 7 7 7 Tetratricopeptide repeat TPR_14 PF13428.1 EIE87992.1 - 5.4e-27 91.8 8.4 0.0016 18.9 0.1 8.5 3 2 6 9 9 9 7 Tetratricopeptide repeat TPR_19 PF14559.1 EIE87992.1 - 1.3e-24 86.2 14.1 6.6e-06 26.3 0.9 6.2 3 2 1 5 5 5 5 Tetratricopeptide repeat TPR_6 PF13174.1 EIE87992.1 - 3.4e-18 64.7 23.2 0.016 15.6 0.0 8.9 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_9 PF13371.1 EIE87992.1 - 9.9e-18 63.7 9.5 0.00049 19.9 0.1 5.5 3 3 2 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.1 EIE87992.1 - 2.4e-16 58.1 20.8 0.059 13.2 0.0 8.6 8 2 0 8 8 8 6 Tetratricopeptide repeat Apc3 PF12895.2 EIE87992.1 - 7.6e-12 45.2 17.1 2.7e-06 27.3 1.8 4.2 3 1 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 EIE87992.1 - 2.7e-08 33.2 8.6 0.023 13.7 1.1 4.6 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_20 PF14561.1 EIE87992.1 - 3.2e-05 23.9 0.1 3.6 7.7 0.0 5.0 3 2 2 5 5 5 1 Tetratricopeptide repeat DUF2225 PF09986.4 EIE87992.1 - 0.00025 20.5 5.0 0.26 10.7 0.1 3.1 2 2 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2225) TPR_21 PF09976.4 EIE87992.1 - 0.00029 20.7 6.1 2.7 7.9 0.1 4.8 4 1 0 5 5 5 2 Tetratricopeptide repeat SNAP PF14938.1 EIE87992.1 - 0.0018 17.4 14.0 0.27 10.3 1.3 4.1 1 1 2 3 3 3 1 Soluble NSF attachment protein, SNAP ChAPs PF09295.5 EIE87992.1 - 0.0085 14.9 2.4 6.2 5.4 0.1 3.2 2 1 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) Tcf25 PF04910.9 EIE87992.1 - 0.054 12.4 5.1 0.58 9.0 0.0 3.7 3 1 0 4 4 4 0 Transcriptional repressor TCF25 MIT PF04212.13 EIE87992.1 - 0.35 10.7 22.7 2.6 8.0 0.2 5.7 5 1 0 5 5 5 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.1 EIE87992.1 - 0.61 10.1 22.5 1.6 8.8 0.0 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat BTAD PF03704.12 EIE87992.1 - 0.78 10.0 7.8 9 6.5 0.3 3.1 2 1 1 3 3 3 0 Bacterial transcriptional activator domain RPN7 PF10602.4 EIE87992.1 - 1.5 8.1 7.3 11 5.3 0.0 4.1 3 2 2 5 5 5 0 26S proteasome subunit RPN7 BBP1_N PF15271.1 EIE87992.1 - 3 8.2 7.2 9.7 6.5 5.0 1.8 1 1 0 1 1 1 0 Spindle pole body component BBP1, Mps2-binding protein DUF1751 PF08551.5 EIE87993.1 - 2.2e-28 98.4 4.5 5.8e-28 97.1 3.1 1.8 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 EIE87993.1 - 8.6e-10 38.8 12.1 1.6e-09 37.9 8.4 1.4 1 0 0 1 1 1 1 Rhomboid family E2F_TDP PF02319.15 EIE87994.1 - 1.3e-23 82.3 0.2 1.3e-23 82.3 0.1 2.1 2 0 0 2 2 2 1 E2F/DP family winged-helix DNA-binding domain TMF_TATA_bd PF12325.3 EIE87994.1 - 0.00085 19.0 2.3 0.0017 18.0 1.6 1.6 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding IncA PF04156.9 EIE87994.1 - 0.0023 17.5 3.3 0.003 17.1 2.3 1.4 1 0 0 1 1 1 1 IncA protein Tropomyosin_1 PF12718.2 EIE87994.1 - 0.0025 17.6 5.1 0.0062 16.3 3.5 1.6 1 0 0 1 1 1 1 Tropomyosin like APG6 PF04111.7 EIE87994.1 - 0.0046 16.0 4.8 0.0046 16.0 3.4 1.4 2 0 0 2 2 2 1 Autophagy protein Apg6 EAP30 PF04157.11 EIE87994.1 - 0.015 14.4 0.9 0.03 13.4 0.5 1.6 1 1 0 1 1 1 0 EAP30/Vps36 family Peptidase_C47 PF05543.8 EIE87994.1 - 0.017 14.5 0.2 2.6 7.4 0.0 2.3 2 0 0 2 2 2 0 Staphopain peptidase C47 DUF724 PF05266.9 EIE87994.1 - 0.043 13.4 1.4 0.043 13.4 1.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Baculo_PEP_C PF04513.7 EIE87994.1 - 0.1 12.4 0.7 0.22 11.3 0.5 1.6 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3086 PF11285.3 EIE87994.1 - 0.41 9.4 4.2 0.66 8.7 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) UPF0122 PF04297.9 EIE87994.1 - 1.3 9.1 0.0 1.3 9.1 0.0 3.8 4 2 0 4 4 4 0 Putative helix-turn-helix protein, YlxM / p13 like DUF4140 PF13600.1 EIE87994.1 - 1.9 8.9 4.4 0.87 10.0 0.8 2.1 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) AF0941-like PF14591.1 EIE87994.1 - 2.6 8.1 8.7 1.1 9.3 2.1 2.5 2 1 1 3 3 3 0 AF0941-like bZIP_1 PF00170.16 EIE87994.1 - 3.2 7.7 12.3 0.29 11.1 4.8 2.1 2 0 0 2 2 2 0 bZIP transcription factor DivIC PF04977.10 EIE87994.1 - 9.6 5.7 9.9 5.1 6.6 4.6 2.3 2 1 0 2 2 2 0 Septum formation initiator DDE_1 PF03184.14 EIE87996.1 - 3.3e-19 68.8 0.3 1.6e-16 60.1 0.4 2.6 1 1 1 2 2 2 2 DDE superfamily endonuclease DDE_3 PF13358.1 EIE87996.1 - 0.082 12.6 0.0 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 DDE superfamily endonuclease SWIM PF04434.12 EIE87997.1 - 5.2e-07 29.0 1.9 7.8e-07 28.4 1.3 1.3 1 0 0 1 1 1 1 SWIM zinc finger Peptidase_M49 PF03571.10 EIE87998.1 - 0.00026 19.2 0.5 0.0023 16.0 0.1 2.2 1 1 1 2 2 2 2 Peptidase family M49 Mito_carr PF00153.22 EIE87999.1 - 4.9e-66 218.4 4.9 1.6e-22 78.9 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein NUDIX PF00293.23 EIE88001.1 - 2.1e-15 56.5 0.2 2.5e-15 56.3 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain YgaB PF14182.1 EIE88001.1 - 0.014 15.6 1.0 0.026 14.7 0.7 1.5 1 0 0 1 1 1 0 YgaB-like protein GTP_EFTU PF00009.22 EIE88002.1 - 6.5e-42 143.1 1.6 6.5e-42 143.1 1.1 2.5 2 1 0 2 2 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EIE88002.1 - 2e-29 101.6 2.9 2e-29 101.6 2.0 2.0 2 0 0 2 2 2 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 EIE88002.1 - 9.6e-13 48.0 5.9 8.2e-06 25.8 0.2 3.2 3 0 0 3 3 3 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EIE88002.1 - 1.4e-08 34.7 0.1 4.2e-08 33.1 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EIE88002.1 - 8.2e-07 29.5 0.0 2.9e-06 27.7 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIE88002.1 - 5.9e-05 22.3 0.0 0.00016 21.0 0.0 1.7 1 0 0 1 1 1 1 ADP-ribosylation factor family FeoB_N PF02421.13 EIE88002.1 - 0.00033 19.9 1.9 0.0014 17.9 0.0 2.7 2 1 0 2 2 2 1 Ferrous iron transport protein B SRPRB PF09439.5 EIE88002.1 - 0.001 18.3 0.1 0.0033 16.6 0.1 1.9 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 EIE88002.1 - 0.0018 17.7 0.1 0.0056 16.1 0.1 1.9 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 EIE88002.1 - 0.032 13.9 0.1 0.12 12.0 0.1 2.1 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Rotamase_2 PF13145.1 EIE88002.1 - 0.12 13.0 5.5 0.087 13.4 1.4 2.4 2 0 0 2 2 2 0 PPIC-type PPIASE domain Dynamin_N PF00350.18 EIE88002.1 - 0.5 10.1 10.4 1.8 8.3 0.1 3.8 3 1 1 4 4 4 0 Dynamin family PH PF00169.24 EIE88003.1 - 0.00019 21.5 0.2 0.0011 19.1 0.1 2.1 1 1 0 1 1 1 1 PH domain Disaggr_repeat PF06848.6 EIE88004.1 - 0.048 13.0 0.0 0.053 12.9 0.0 1.1 1 0 0 1 1 1 0 Disaggregatase related repeat Cas_Csy1 PF09611.5 EIE88004.1 - 0.086 11.7 1.3 0.1 11.5 0.9 1.0 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy1) UTP15_C PF09384.5 EIE88007.1 - 3.3e-45 153.4 0.1 5.9e-45 152.5 0.1 1.4 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.27 EIE88007.1 - 3.2e-27 93.3 4.3 7.6e-06 25.6 0.1 7.0 7 0 0 7 7 7 4 WD domain, G-beta repeat Nup160 PF11715.3 EIE88007.1 - 0.037 12.1 0.1 0.2 9.7 0.1 2.2 2 1 0 2 2 2 0 Nucleoporin Nup120/160 BSP_II PF05432.6 EIE88009.1 - 0.041 13.1 8.8 0.044 13.0 6.1 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) HDV_ag PF01517.13 EIE88009.1 - 0.064 12.9 9.8 0.079 12.6 6.8 1.1 1 0 0 1 1 1 0 Hepatitis delta virus delta antigen Sigma70_ner PF04546.8 EIE88009.1 - 0.22 11.1 10.3 0.26 10.8 7.1 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Presenilin PF01080.12 EIE88009.1 - 0.26 10.0 11.7 0.29 9.9 8.1 1.0 1 0 0 1 1 1 0 Presenilin DUF966 PF06136.8 EIE88009.1 - 0.73 9.1 12.7 0.78 9.0 8.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) AIF-MLS PF14962.1 EIE88009.1 - 0.91 9.1 11.2 1.1 8.9 7.7 1.2 1 0 0 1 1 1 0 Mitochondria Localisation Sequence DUF3537 PF12056.3 EIE88009.1 - 2.1 6.9 6.3 2.5 6.6 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) FancD2 PF14631.1 EIE88009.1 - 2.2 5.2 11.8 2.6 5.0 8.1 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease FAM60A PF15396.1 EIE88009.1 - 2.9 7.5 11.2 3.4 7.3 7.8 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Cwf_Cwc_15 PF04889.7 EIE88009.1 - 3.4 7.3 21.2 4.4 6.9 14.7 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF1510 PF07423.6 EIE88009.1 - 3.8 6.8 21.4 4.5 6.5 14.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF3807 PF12720.2 EIE88009.1 - 4.6 7.3 15.2 5.9 7.0 10.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Zip PF02535.17 EIE88009.1 - 5.4 5.9 5.9 5.7 5.8 4.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.9 EIE88009.1 - 5.4 4.9 11.9 6 4.7 8.3 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF1764 PF08576.5 EIE88009.1 - 6.3 7.6 20.5 14 6.5 14.2 1.7 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) RR_TM4-6 PF06459.7 EIE88009.1 - 6.7 6.5 19.8 8.6 6.1 13.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FNIP_N PF14636.1 EIE88009.1 - 9.3 6.7 11.8 14 6.2 8.2 1.4 1 1 0 1 1 1 0 Folliculin-interacting protein N-terminus zf-UBR PF02207.15 EIE88010.1 - 5.2e-18 64.5 13.6 5.2e-18 64.5 9.4 3.6 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 EIE88010.1 - 1.3e-15 56.8 0.2 3.6e-15 55.4 0.1 1.8 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS ECH PF00378.15 EIE88011.1 - 5.7e-51 173.0 0.0 8.1e-51 172.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 EIE88011.1 - 0.026 14.6 0.1 0.047 13.8 0.0 1.4 1 0 0 1 1 1 0 2-enoyl-CoA Hydratase C-terminal region ubiquitin PF00240.18 EIE88012.1 - 2.3e-68 225.4 8.2 6.6e-34 115.1 0.6 2.2 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.3 EIE88012.1 - 3.9e-39 132.1 7.0 2.5e-19 68.6 0.5 2.2 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EIE88012.1 - 3.3e-12 46.4 2.3 9.2e-05 22.6 0.1 3.2 2 2 0 2 2 2 2 Ubiquitin-like domain zf-AN1 PF01428.11 EIE88012.1 - 1.7e-10 40.5 10.9 2.7e-10 39.9 7.6 1.3 1 0 0 1 1 1 1 AN1-like Zinc finger Telomere_Sde2 PF13019.1 EIE88012.1 - 1.8e-09 37.4 4.9 9.1e-05 22.1 0.0 2.4 3 0 0 3 3 2 2 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EIE88012.1 - 2.2e-08 33.9 0.9 0.00086 19.1 0.1 2.7 2 2 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EIE88012.1 - 6.3e-07 29.5 1.4 0.011 15.9 0.2 2.3 1 1 1 2 2 2 2 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 EIE88012.1 - 6.3e-05 22.9 0.0 0.39 10.7 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF2870) TUG-UBL1 PF11470.3 EIE88012.1 - 0.0036 17.1 0.6 2.8 7.9 0.0 2.4 2 0 0 2 2 2 2 GLUT4 regulating protein TUG Plexin_cytopl PF08337.7 EIE88012.1 - 0.005 15.2 4.1 1.5 7.0 0.2 3.4 3 1 0 3 3 3 2 Plexin cytoplasmic RasGAP domain FlgD_ig PF13860.1 EIE88012.1 - 0.021 14.5 0.5 6.5 6.5 0.0 2.3 2 0 0 2 2 2 0 FlgD Ig-like domain DUF3861 PF12977.2 EIE88012.1 - 0.049 13.7 1.2 12 6.1 0.0 3.1 1 1 1 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3861) GABP-alpha PF11620.3 EIE88012.1 - 0.2 11.6 1.4 16 5.5 0.1 2.3 2 0 0 2 2 2 0 GA-binding protein alpha chain Tash_PEST PF07708.6 EIE88012.1 - 0.3 11.0 11.2 2.5 8.1 1.2 2.3 2 0 0 2 2 2 0 Tash protein PEST motif DUF2788 PF10981.3 EIE88015.1 - 0.039 13.7 0.1 0.055 13.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2788) DUF420 PF04238.7 EIE88016.1 - 0.1 12.5 0.1 0.1 12.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF420) Plasmodium_HRP PF05403.6 EIE88017.1 - 9.2e-07 28.6 85.7 3.1e-05 23.6 41.8 2.1 1 1 1 2 2 2 2 Plasmodium histidine-rich protein (HRPII/III) FAM196 PF15265.1 EIE88017.1 - 2 7.5 39.9 2.7 7.1 27.6 1.1 1 0 0 1 1 1 0 FAM196 family DUF3868 PF12984.2 EIE88018.1 - 0.14 11.6 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3868) NCD2 PF04905.8 EIE88019.1 - 2.6e-07 30.5 0.1 2.6e-07 30.5 0.1 2.9 2 1 1 3 3 3 1 NAB conserved region 2 (NCD2) SAM_2 PF07647.12 EIE88019.1 - 0.0063 16.3 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EIE88019.1 - 0.049 13.8 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Pkinase PF00069.20 EIE88020.1 - 4.2e-49 167.0 0.2 6.2e-49 166.4 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE88020.1 - 1.5e-24 86.4 0.0 2.7e-24 85.6 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE88020.1 - 0.058 12.3 0.0 0.092 11.6 0.0 1.5 1 0 0 1 1 1 0 Kinase-like SKIP_SNW PF02731.10 EIE88020.1 - 0.12 11.7 8.6 0.25 10.7 5.9 1.5 1 0 0 1 1 1 0 SKIP/SNW domain HLH PF00010.21 EIE88021.1 - 6.9e-09 35.2 2.6 1.3e-08 34.3 0.9 2.3 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain MerR-DNA-bind PF09278.6 EIE88021.1 - 2.2 8.7 11.4 0.13 12.6 0.6 3.1 2 0 0 2 2 2 0 MerR, DNA binding YjeF_N PF03853.10 EIE88022.1 - 3.5e-29 101.5 0.0 7.7e-29 100.4 0.0 1.6 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.5 EIE88022.1 - 1.6e-06 28.5 1.9 1.6e-06 28.5 1.3 2.3 2 0 0 2 2 2 1 FDF domain LSM14 PF12701.2 EIE88022.1 - 0.0016 18.2 0.1 0.046 13.5 0.1 2.7 1 1 0 1 1 1 1 Scd6-like Sm domain DUF1344 PF07076.6 EIE88022.1 - 0.067 12.7 0.0 0.18 11.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1344) DUF3772 PF12607.3 EIE88022.1 - 0.073 12.7 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3772) adh_short PF00106.20 EIE88022.1 - 0.11 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase NST1 PF13945.1 EIE88022.1 - 4.6 7.2 16.1 6.5 6.7 11.2 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator efThoc1 PF11957.3 EIE88023.1 - 6e-89 298.7 0.4 8.9e-89 298.2 0.3 1.1 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor Thaumatin PF00314.12 EIE88023.1 - 1.4e-45 155.3 9.3 8.1e-45 152.8 6.4 2.0 1 1 0 1 1 1 1 Thaumatin family Glyco_hydro_85 PF03644.8 EIE88024.1 - 2.5e-37 128.6 0.1 2.8e-37 128.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 WLM PF08325.5 EIE88025.1 - 9.9e-43 146.1 0.0 1.3e-42 145.7 0.0 1.1 1 0 0 1 1 1 1 WLM domain Peptidase_MA_2 PF13485.1 EIE88025.1 - 0.0065 16.5 0.2 0.013 15.5 0.2 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily DUF45 PF01863.12 EIE88025.1 - 0.044 13.5 0.7 0.11 12.2 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF45 Dymeclin PF09742.4 EIE88027.1 - 1.8e-43 148.6 7.1 2e-43 148.5 4.9 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Hid1 PF12722.2 EIE88027.1 - 0.00038 18.2 2.8 0.00046 18.0 1.9 1.1 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Avl9 PF09794.4 EIE88027.1 - 0.04 12.3 2.7 0.049 12.1 1.9 1.1 1 0 0 1 1 1 0 Transport protein Avl9 Kinesin PF00225.18 EIE88029.1 - 8.5e-87 290.9 7.4 1.8e-59 201.1 1.5 3.5 3 2 1 4 4 4 2 Kinesin motor domain Abhydrolase_3 PF07859.8 EIE88030.1 - 6.8e-27 94.4 0.0 1.1e-26 93.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EIE88030.1 - 8.8e-13 47.6 0.6 1.4e-11 43.7 0.4 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EIE88030.1 - 0.002 17.8 0.0 0.0031 17.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EIE88030.1 - 0.011 14.9 0.0 0.025 13.7 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EIE88030.1 - 0.053 13.3 0.0 0.07 12.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Microtub_assoc PF07989.6 EIE88032.1 - 3.4e-18 65.2 4.9 3.4e-18 65.2 3.4 7.8 5 3 2 7 7 7 1 Microtubule associated TPR_MLP1_2 PF07926.7 EIE88032.1 - 0.006 16.3 4.0 0.006 16.3 2.7 7.1 2 1 5 7 7 7 1 TPR/MLP1/MLP2-like protein Cep57_CLD_2 PF14197.1 EIE88032.1 - 0.097 12.6 0.2 0.097 12.6 0.1 8.7 5 3 3 8 8 8 0 Centrosome localisation domain of PPC89 Filament PF00038.16 EIE88032.1 - 0.86 9.0 86.2 0.09 12.2 20.5 3.4 1 1 1 2 2 2 0 Intermediate filament protein APG6 PF04111.7 EIE88032.1 - 4.9 6.0 99.1 0.035 13.1 10.3 5.1 1 1 5 6 6 6 0 Autophagy protein Apg6 PK PF00224.16 EIE88033.1 - 2.1e-139 463.9 5.8 1.5e-96 323.0 0.7 2.1 1 1 1 2 2 2 2 Pyruvate kinase, barrel domain PK_C PF02887.11 EIE88033.1 - 3.4e-30 104.0 0.0 6.4e-30 103.1 0.0 1.5 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 EIE88033.1 - 0.0019 17.1 0.6 0.0054 15.6 0.4 1.8 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.20 EIE88033.1 - 0.0074 15.2 0.5 0.037 12.9 0.0 2.2 2 1 0 3 3 3 1 IMP dehydrogenase / GMP reductase domain PRK PF00485.13 EIE88034.1 - 2.2e-29 102.4 0.0 2.8e-29 102.0 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 EIE88034.1 - 0.0057 16.9 0.2 0.013 15.8 0.1 1.6 1 1 0 1 1 1 1 AAA domain Spore_II_R PF09551.5 EIE88034.1 - 0.13 12.3 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Stage II sporulation protein R (spore_II_R) GATA PF00320.22 EIE88035.1 - 3.8e-27 93.3 17.5 1.1e-14 53.4 2.4 2.7 2 0 0 2 2 2 2 GATA zinc finger DUF1752 PF08550.5 EIE88035.1 - 3.8e-11 42.3 1.8 2.3e-10 39.8 0.5 2.6 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1752) Zn-ribbon_8 PF09723.5 EIE88035.1 - 0.024 14.5 1.4 2.4 8.1 0.0 2.6 2 0 0 2 2 2 0 Zinc ribbon domain DZR PF12773.2 EIE88035.1 - 0.066 13.0 8.4 1.7 8.5 0.1 3.1 2 1 1 3 3 3 0 Double zinc ribbon TF_Zn_Ribbon PF08271.7 EIE88035.1 - 0.13 11.6 5.8 1.5 8.2 0.3 2.6 2 0 0 2 2 2 0 TFIIB zinc-binding zf-ribbon_3 PF13248.1 EIE88035.1 - 0.14 11.4 7.9 0.35 10.1 0.4 2.8 2 1 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.2 EIE88035.1 - 0.28 11.0 2.1 18 5.2 0.1 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain HNH PF01844.18 EIE88035.1 - 0.3 10.9 4.9 0.89 9.4 0.6 2.6 2 0 0 2 2 2 0 HNH endonuclease Serinc PF03348.10 EIE88035.1 - 6.4 5.3 6.4 12 4.5 4.4 1.4 1 0 0 1 1 1 0 Serine incorporator (Serinc) HTH_32 PF13565.1 EIE88037.1 - 0.011 16.5 0.0 0.032 15.0 0.0 1.9 1 1 1 2 2 2 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.13 EIE88037.1 - 0.066 13.2 0.1 0.4 10.7 0.0 2.3 2 1 1 3 3 3 0 Transposase RasGEF PF00617.14 EIE88038.1 - 6.8e-44 149.8 0.3 1.6e-43 148.6 0.2 1.7 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EIE88038.1 - 2.2e-18 66.2 3.8 1.5e-17 63.5 2.6 2.5 1 0 0 1 1 1 1 RasGEF N-terminal motif Ank_2 PF12796.2 EIE88039.1 - 4.5e-53 177.5 5.9 2.5e-17 62.9 0.3 2.9 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EIE88039.1 - 1.3e-29 100.4 3.1 1.6e-08 33.9 0.2 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 EIE88039.1 - 5.9e-28 96.7 1.3 1e-07 32.2 0.0 4.3 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIE88039.1 - 5.6e-24 81.8 1.7 8.2e-05 22.4 0.0 5.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 EIE88039.1 - 2.5e-22 78.3 5.5 4.1e-07 30.0 1.9 4.4 1 1 4 5 5 5 4 Ankyrin repeats (many copies) DUF285 PF03382.9 EIE88041.1 - 0.0054 16.2 0.0 0.2 11.2 0.0 2.2 2 0 0 2 2 2 2 Mycoplasma protein of unknown function, DUF285 PIF1 PF05970.9 EIE88042.1 - 2.5e-16 59.5 0.2 3e-16 59.3 0.1 1.1 1 0 0 1 1 1 1 PIF1-like helicase PIF1 PF05970.9 EIE88043.1 - 9.7e-30 103.7 0.0 1e-29 103.6 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 EIE88043.1 - 1.5e-06 27.9 0.0 1.7e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EIE88043.1 - 8.8e-05 22.1 0.0 0.0001 21.9 0.0 1.1 1 0 0 1 1 1 1 Part of AAA domain ResIII PF04851.10 EIE88043.1 - 0.0021 17.9 0.0 0.0024 17.7 0.0 1.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.4 EIE88043.1 - 0.005 15.5 0.0 0.0058 15.3 0.0 1.1 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain DAP3 PF10236.4 EIE88043.1 - 0.016 14.1 0.0 0.019 13.9 0.0 1.0 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 PhoH PF02562.11 EIE88043.1 - 0.018 14.2 0.0 0.019 14.1 0.0 1.1 1 0 0 1 1 1 0 PhoH-like protein SRP54 PF00448.17 EIE88043.1 - 0.043 13.2 0.0 0.057 12.8 0.0 1.1 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain T2SE PF00437.15 EIE88043.1 - 0.056 12.3 0.0 0.063 12.1 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF2075 PF09848.4 EIE88043.1 - 0.063 12.2 0.0 0.07 12.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.1 EIE88043.1 - 0.064 13.2 0.0 0.074 13.0 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.9 EIE88043.1 - 0.079 12.6 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EIE88043.1 - 0.1 12.7 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EIE88043.1 - 0.11 11.9 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Sigma-54 interaction domain PALP PF00291.20 EIE88043.1 - 0.14 11.3 0.0 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme GFA PF04828.9 EIE88045.1 - 0.075 12.9 2.1 0.17 11.8 1.5 1.6 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme Spectrin PF00435.16 EIE88046.1 - 0.0093 16.2 1.0 0.025 14.8 0.3 1.9 2 0 0 2 2 2 1 Spectrin repeat TniQ PF06527.6 EIE88046.1 - 0.019 15.1 0.0 0.031 14.4 0.0 1.4 1 1 0 1 1 1 0 TniQ LRR_4 PF12799.2 EIE88047.1 - 0.044 13.4 0.0 0.093 12.3 0.0 1.5 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) zf-RVT PF13966.1 EIE88051.1 - 3.2e-06 27.3 0.8 7.7e-06 26.1 0.6 1.6 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Kinesin PF00225.18 EIE88052.1 - 3e-91 305.6 3.5 3e-91 305.6 2.4 4.5 4 2 0 5 5 5 1 Kinesin motor domain GATA PF00320.22 EIE88053.1 - 0.2 11.0 1.6 0.36 10.2 1.1 1.4 1 0 0 1 1 1 0 GATA zinc finger SDA1 PF05285.7 EIE88053.1 - 0.31 10.2 8.7 0.44 9.7 6.0 1.2 1 0 0 1 1 1 0 SDA1 Mit_ribos_Mrp51 PF11709.3 EIE88053.1 - 0.78 8.9 6.3 0.86 8.7 3.6 1.6 1 1 1 2 2 2 0 Mitochondrial ribosomal protein subunit Polysacc_deac_1 PF01522.16 EIE88055.1 - 5.9e-25 87.3 0.0 1.1e-24 86.4 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Polysacc_deac_1 PF01522.16 EIE88056.1 - 4.8e-26 90.8 0.0 9.4e-26 89.8 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Kinesin PF00225.18 EIE88057.1 - 1.2e-83 280.6 4.2 1.2e-83 280.6 2.9 4.4 3 1 0 3 3 3 1 Kinesin motor domain Not3 PF04065.10 EIE88060.1 - 2.9 7.0 12.9 1.6 7.9 1.6 2.5 2 1 0 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component PX PF00787.19 EIE88061.1 - 2.3e-10 40.2 0.6 5.2e-10 39.1 0.2 1.8 2 0 0 2 2 2 1 PX domain Vps5 PF09325.5 EIE88061.1 - 6.6e-06 25.5 1.0 6.6e-06 25.5 0.7 2.0 2 1 0 2 2 2 1 Vps5 C terminal like Pro_isomerase PF00160.16 EIE88062.1 - 4.7e-29 101.6 0.0 7.8e-29 100.8 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD U1snRNP70_N PF12220.3 EIE88062.1 - 1.4 9.3 7.7 3.9 7.8 2.4 2.2 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Rtf2 PF04641.7 EIE88063.1 - 3.2e-09 36.3 0.2 5.1e-09 35.7 0.1 1.3 1 0 0 1 1 1 1 Rtf2 RING-finger U-box PF04564.10 EIE88063.1 - 9.4e-07 28.7 0.9 9.2e-05 22.3 0.0 2.7 2 1 0 2 2 2 1 U-box domain TMEM206 PF15122.1 EIE88063.1 - 0.031 13.2 0.1 0.43 9.4 0.0 2.0 1 1 1 2 2 2 0 TMEM206 protein family zf-Nse PF11789.3 EIE88063.1 - 0.088 12.3 2.6 0.69 9.4 1.2 2.7 2 1 1 3 3 3 0 Zinc-finger of the MIZ type in Nse subunit DUF2407 PF10302.4 EIE88064.1 - 0.81 9.9 4.3 15 5.8 1.6 2.6 2 1 0 2 2 2 0 DUF2407 ubiquitin-like domain DUF4094 PF13334.1 EIE88064.1 - 5 7.5 6.6 1.6 9.2 2.0 2.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4094) AAA_23 PF13476.1 EIE88065.1 - 0.015 15.6 6.2 0.024 14.9 4.3 1.3 1 0 0 1 1 1 0 AAA domain DUF676 PF05057.9 EIE88065.1 - 0.066 12.5 0.0 0.3 10.3 0.0 2.0 2 0 0 2 2 2 0 Putative serine esterase (DUF676) Ferrochelatase PF00762.14 EIE88065.1 - 0.076 11.9 0.2 0.18 10.7 0.1 1.6 1 1 0 1 1 1 0 Ferrochelatase DUF1993 PF09351.5 EIE88065.1 - 0.14 12.0 0.2 0.22 11.4 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1993) Trehalase PF01204.13 EIE88066.1 - 9.1e-163 542.5 0.9 1.9e-162 541.5 0.6 1.5 1 1 0 1 1 1 1 Trehalase MMR_HSR1 PF01926.18 EIE88067.1 - 1.1e-15 57.5 0.0 1.7e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase IIGP PF05049.8 EIE88067.1 - 1e-05 24.5 0.9 1.5e-05 23.9 0.1 1.6 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) DUF258 PF03193.11 EIE88067.1 - 1.5e-05 24.2 0.0 3.1e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 EIE88067.1 - 1.6e-05 24.2 0.0 2.6e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B AIG1 PF04548.11 EIE88067.1 - 0.00034 19.7 0.2 0.00065 18.8 0.1 1.4 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.18 EIE88067.1 - 0.00045 20.0 1.4 0.091 12.5 0.1 2.4 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 EIE88067.1 - 0.059 13.8 0.1 0.21 12.0 0.1 2.0 2 0 0 2 2 2 0 Miro-like protein Septin PF00735.13 EIE88067.1 - 0.059 12.3 0.0 0.09 11.7 0.0 1.2 1 0 0 1 1 1 0 Septin MobB PF03205.9 EIE88067.1 - 0.074 12.7 0.2 0.13 11.9 0.2 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.1 EIE88067.1 - 0.12 11.9 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RRM_1 PF00076.17 EIE88068.1 - 3.8e-18 64.8 0.0 6.8e-18 64.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE88068.1 - 8.6e-10 38.4 0.0 1.3e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE88068.1 - 1.4e-05 24.8 0.0 2.4e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TM2 PF05154.11 EIE88069.1 - 5.7e-15 55.2 8.4 1.2e-14 54.1 5.8 1.5 1 0 0 1 1 1 1 TM2 domain 5_nucleotid_C PF02872.13 EIE88071.1 - 2.5e-33 115.2 0.0 7.7e-33 113.6 0.0 1.7 1 1 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 EIE88071.1 - 0.00062 19.2 0.6 0.0018 17.7 0.4 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Mito_carr PF00153.22 EIE88073.1 - 6.3e-26 89.9 4.4 2.3e-08 33.5 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Daxx PF03344.10 EIE88074.1 - 0.069 11.6 42.9 0.1 11.0 29.8 1.3 1 0 0 1 1 1 0 Daxx Family Macoilin PF09726.4 EIE88074.1 - 2.5 6.2 22.3 2.7 6.1 15.5 1.0 1 0 0 1 1 1 0 Transmembrane protein TFIIF_alpha PF05793.7 EIE88074.1 - 6.4 5.0 62.2 8 4.7 43.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SPT6_acidic PF14632.1 EIE88075.1 - 0.027 14.6 9.6 0.037 14.1 6.7 1.2 1 0 0 1 1 1 0 Acidic N-terminal SPT6 RP-C_C PF11800.3 EIE88075.1 - 0.19 11.4 2.1 0.21 11.2 1.5 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region Protocadherin PF08374.6 EIE88075.1 - 0.27 10.8 4.2 0.3 10.6 2.9 1.2 1 0 0 1 1 1 0 Protocadherin RNA_polI_A34 PF08208.6 EIE88075.1 - 0.83 9.2 13.4 0.94 9.1 9.3 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF1510 PF07423.6 EIE88075.1 - 1.7 7.9 11.3 1.8 7.8 7.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) FLO_LFY PF01698.11 EIE88075.1 - 1.7 7.3 8.1 2.2 7.0 5.6 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein CDC45 PF02724.9 EIE88075.1 - 6.2 4.7 7.5 7.1 4.5 5.2 1.0 1 0 0 1 1 1 0 CDC45-like protein RNA_pol_Rpc4 PF05132.9 EIE88075.1 - 6.9 6.6 9.3 10 6.1 6.4 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 PPI_Ypi1 PF07491.6 EIE88076.1 - 0.042 13.4 1.0 0.088 12.4 0.7 1.5 1 0 0 1 1 1 0 Protein phosphatase inhibitor NST1 PF13945.1 EIE88076.1 - 0.35 10.9 5.0 0.36 10.8 3.5 1.0 1 0 0 1 1 1 0 Salt tolerance down-regulator DUF2681 PF10883.3 EIE88076.1 - 8.7 6.6 8.0 14 5.9 5.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Di19_C PF14571.1 EIE88076.1 - 9.9 6.5 7.2 13 6.1 5.0 1.2 1 0 0 1 1 1 0 Stress-induced protein Di19, C-terminal Striatin PF08232.7 EIE88077.1 - 0.013 15.8 5.8 0.013 15.8 4.0 3.0 1 1 0 2 2 2 0 Striatin family Med15_fungi PF05397.7 EIE88077.1 - 0.013 15.4 2.7 0.013 15.4 1.9 2.0 1 1 1 2 2 2 0 Mediator complex subunit 15 Cupin_8 PF13621.1 EIE88077.1 - 0.015 14.8 4.6 0.034 13.6 3.2 1.7 1 1 0 1 1 1 0 Cupin-like domain Fib_alpha PF08702.5 EIE88077.1 - 8.5 6.4 17.3 2.2 8.3 1.3 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF3659 PF12396.3 EIE88078.1 - 3.4e-33 113.1 9.8 4.4e-18 64.7 0.7 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF3659) DUF1993 PF09351.5 EIE88078.1 - 0.049 13.5 0.3 0.049 13.5 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1993) TRAP_alpha PF03896.11 EIE88078.1 - 1.5 7.7 14.4 0.029 13.3 3.4 2.3 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Lipase_GDSL PF00657.17 EIE88080.1 - 5e-11 42.8 0.2 8.4e-11 42.1 0.1 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EIE88080.1 - 9.6e-08 32.3 0.0 1.8e-06 28.2 0.0 2.1 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Gtr1_RagA PF04670.7 EIE88081.1 - 1.2e-56 191.4 6.9 4.7e-56 189.5 4.8 1.9 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 EIE88081.1 - 3.9e-06 26.2 0.1 8.3e-06 25.1 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EIE88081.1 - 0.00037 20.4 0.1 0.0017 18.2 0.0 2.2 1 1 0 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.5 EIE88081.1 - 0.00092 18.4 0.0 0.002 17.3 0.0 1.6 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FliS PF02561.9 EIE88081.1 - 0.014 15.2 1.5 0.046 13.5 1.1 1.8 1 0 0 1 1 1 0 Flagellar protein FliS Miro PF08477.8 EIE88081.1 - 0.059 13.8 1.5 0.23 11.9 0.1 2.6 2 1 1 3 3 3 0 Miro-like protein TBPIP PF07106.8 EIE88082.1 - 7.4e-31 106.9 14.5 9.3e-31 106.6 10.1 1.1 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DivIC PF04977.10 EIE88082.1 - 0.00044 19.6 13.6 0.00062 19.1 3.3 3.0 1 1 2 3 3 3 1 Septum formation initiator Syntaxin PF00804.20 EIE88082.1 - 0.00073 19.6 3.6 0.0015 18.6 2.5 1.6 1 0 0 1 1 1 1 Syntaxin DUF1319 PF07028.6 EIE88082.1 - 0.0029 17.7 1.1 0.0029 17.7 0.8 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF1319) Tmemb_cc2 PF10267.4 EIE88082.1 - 0.0099 14.5 8.0 0.013 14.1 5.6 1.2 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein Latarcin PF10279.4 EIE88082.1 - 0.019 15.1 6.2 0.019 15.1 4.3 2.2 2 0 0 2 2 2 0 Latarcin precursor Cob_adeno_trans PF01923.13 EIE88082.1 - 0.025 14.3 0.3 0.038 13.7 0.2 1.2 1 0 0 1 1 1 0 Cobalamin adenosyltransferase Ax_dynein_light PF10211.4 EIE88082.1 - 0.045 13.5 8.4 0.091 12.5 5.8 1.5 1 0 0 1 1 1 0 Axonemal dynein light chain Peptidase_S46 PF10459.4 EIE88082.1 - 0.046 12.1 5.4 0.05 12.0 3.7 1.1 1 0 0 1 1 1 0 Peptidase S46 Bacillus_HBL PF05791.6 EIE88082.1 - 0.05 12.9 6.7 0.24 10.7 1.8 2.2 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) IncA PF04156.9 EIE88082.1 - 0.055 13.0 10.9 0.088 12.3 6.9 1.6 1 1 0 1 1 1 0 IncA protein DUF342 PF03961.8 EIE88082.1 - 0.12 10.7 12.0 0.19 10.1 8.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF342) DUF3373 PF11853.3 EIE88082.1 - 0.14 10.6 1.1 0.15 10.5 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Erp_C PF06780.6 EIE88082.1 - 0.15 11.9 14.6 0.31 10.8 8.0 2.2 1 1 1 2 2 2 0 Erp protein C-terminus APG6 PF04111.7 EIE88082.1 - 0.16 11.0 8.2 0.2 10.6 5.7 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 TipAS PF07739.8 EIE88082.1 - 0.17 12.1 1.9 0.55 10.5 0.4 2.5 2 1 0 2 2 1 0 TipAS antibiotic-recognition domain Allexi_40kDa PF05549.6 EIE88082.1 - 0.19 10.9 4.4 0.25 10.6 2.7 1.4 1 1 0 1 1 1 0 Allexivirus 40kDa protein Symplekin_C PF12295.3 EIE88082.1 - 0.21 11.4 1.5 1.2 8.9 0.0 2.4 1 1 0 3 3 3 0 Symplekin tight junction protein C terminal TMPIT PF07851.8 EIE88082.1 - 0.24 10.4 2.5 0.36 9.8 1.8 1.2 1 0 0 1 1 1 0 TMPIT-like protein YABBY PF04690.8 EIE88082.1 - 0.27 11.4 1.2 0.43 10.7 0.6 1.4 1 1 0 1 1 1 0 YABBY protein Lip_prot_lig_C PF10437.4 EIE88082.1 - 0.37 10.5 3.8 2.9 7.6 0.5 2.7 2 1 0 2 2 2 0 Bacterial lipoate protein ligase C-terminus Macoilin PF09726.4 EIE88082.1 - 0.37 9.0 8.0 0.45 8.7 5.6 1.1 1 0 0 1 1 1 0 Transmembrane protein Mnd1 PF03962.10 EIE88082.1 - 0.48 10.0 10.7 0.74 9.4 7.4 1.5 1 1 0 1 1 1 0 Mnd1 family DUF3452 PF11934.3 EIE88082.1 - 0.58 9.4 3.3 0.98 8.7 1.7 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3452) DUF1640 PF07798.6 EIE88082.1 - 0.66 9.9 9.0 0.4 10.6 2.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) bZIP_1 PF00170.16 EIE88082.1 - 0.75 9.7 14.5 2.2 8.3 4.7 2.6 1 1 1 2 2 2 0 bZIP transcription factor DUF4298 PF14131.1 EIE88082.1 - 0.77 9.6 4.0 7.2 6.5 2.8 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4298) YlqD PF11068.3 EIE88082.1 - 0.83 9.6 6.7 1.8 8.5 4.7 1.7 1 1 0 1 1 1 0 YlqD protein V_ATPase_I PF01496.14 EIE88082.1 - 1.1 6.9 7.2 1.3 6.7 5.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TSC22 PF01166.13 EIE88082.1 - 1.6 8.7 7.0 3.1 7.8 4.4 1.9 1 1 0 1 1 1 0 TSC-22/dip/bun family UPF0242 PF06785.6 EIE88082.1 - 1.6 7.3 5.9 2 7.0 4.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) DUF972 PF06156.8 EIE88082.1 - 2.1 8.7 12.4 1.7 9.0 6.8 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF972) Rootletin PF15035.1 EIE88082.1 - 2.3 8.1 13.5 7.6 6.4 9.3 1.9 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion bZIP_2 PF07716.10 EIE88082.1 - 2.3 8.1 10.5 9.1 6.1 3.2 2.8 2 0 0 2 2 2 0 Basic region leucine zipper DASH_Dad3 PF08656.5 EIE88082.1 - 3.1 7.5 8.7 7.5 6.3 0.1 2.8 1 1 2 3 3 3 0 DASH complex subunit Dad3 Adaptin_binding PF10199.4 EIE88082.1 - 3.4 7.9 10.4 3.1 8.0 6.1 1.9 1 1 1 2 2 2 0 Alpha and gamma adaptin binding protein p34 Nnf1 PF03980.9 EIE88082.1 - 4.4 7.3 11.4 8.5 6.4 4.5 2.8 2 1 0 2 2 2 0 Nnf1 FlaC_arch PF05377.6 EIE88082.1 - 5.8 6.8 9.7 5.7 6.9 3.9 2.4 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) IFP_35_N PF07334.8 EIE88082.1 - 6.3 6.8 8.3 6.7 6.7 2.4 2.5 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DUF3810 PF12725.2 EIE88082.1 - 7 5.4 8.1 5.2 5.8 3.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3810) DUF904 PF06005.7 EIE88082.1 - 7 7.0 16.4 3.9e+02 1.4 11.4 2.7 1 1 0 1 1 1 0 Protein of unknown function (DUF904) Abhydrolase_6 PF12697.2 EIE88083.1 - 4.5e-31 108.5 0.0 6.5e-31 107.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIE88083.1 - 2e-16 60.0 0.0 7.2e-16 58.2 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family DSPc PF00782.15 EIE88083.1 - 3.5e-15 55.7 0.0 2.1e-14 53.2 0.0 2.1 1 1 1 2 2 2 1 Dual specificity phosphatase, catalytic domain Abhydrolase_1 PF00561.15 EIE88083.1 - 8.1e-15 54.9 0.0 1.1e-14 54.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.8 EIE88083.1 - 3.9e-06 26.5 0.0 8.2e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase Y_phosphatase PF00102.22 EIE88083.1 - 0.00032 20.1 0.0 0.00079 18.8 0.0 1.6 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Hydrolase_4 PF12146.3 EIE88083.1 - 0.0013 18.5 0.1 0.0025 17.6 0.1 1.6 1 0 0 1 1 1 1 Putative lysophospholipase PTPlike_phytase PF14566.1 EIE88083.1 - 0.0028 17.7 0.0 0.0048 16.9 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Abhydrolase_2 PF02230.11 EIE88083.1 - 0.0062 15.9 0.1 2.8 7.3 0.0 2.6 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase PGAP1 PF07819.8 EIE88083.1 - 0.083 12.4 0.1 0.61 9.6 0.1 2.1 1 1 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.20 EIE88083.1 - 0.11 12.1 0.0 0.3 10.6 0.0 1.8 1 0 0 1 1 1 0 Lipase (class 3) SH3BGR PF04908.10 EIE88084.1 - 6.1e-12 45.3 0.2 6.1e-12 45.3 0.2 3.8 3 2 1 5 5 5 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.19 EIE88084.1 - 0.0001 22.1 0.0 0.00064 19.6 0.0 2.5 1 0 0 1 1 1 1 Glutaredoxin UPF0113 PF03657.8 EIE88085.1 - 2e-06 27.5 0.0 2.9e-06 27.0 0.0 1.3 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0113) Pkinase PF00069.20 EIE88086.1 - 1.8e-73 246.9 0.0 2.3e-73 246.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE88086.1 - 1e-30 106.7 0.0 1.5e-30 106.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EIE88086.1 - 5.9e-05 22.2 0.0 0.00017 20.7 0.0 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIE88086.1 - 0.00066 19.4 0.0 0.001 18.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EIE88086.1 - 0.0012 17.8 0.0 0.042 12.8 0.0 2.2 1 1 0 2 2 2 1 Kinase-like RIO1 PF01163.17 EIE88086.1 - 0.057 12.7 0.0 0.09 12.1 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Sel1 PF08238.7 EIE88087.1 - 6e-10 39.4 0.5 6e-08 33.0 0.0 2.7 3 0 0 3 3 3 1 Sel1 repeat DUF4575 PF15143.1 EIE88087.1 - 0.059 13.1 0.0 0.084 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4575) Methyltransf_11 PF08241.7 EIE88089.1 - 8.8e-08 32.5 0.0 1.5e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIE88089.1 - 8.2e-06 25.4 0.0 1e-05 25.1 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIE88089.1 - 0.0017 17.5 0.0 0.0027 16.8 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 EIE88089.1 - 0.0071 16.0 0.0 0.0074 16.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIE88089.1 - 0.024 14.9 0.0 0.033 14.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_29 PF03141.11 EIE88089.1 - 0.067 11.5 0.0 0.07 11.4 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase PAP_central PF04928.12 EIE88090.1 - 1.8e-99 331.6 0.0 2.5e-99 331.2 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 EIE88090.1 - 6.3e-27 94.0 1.0 7.8e-26 90.4 0.1 2.8 2 1 0 2 2 2 1 Poly(A) polymerase predicted RNA binding domain RRM_1 PF00076.17 EIE88091.1 - 3.1e-12 45.9 0.1 1.7e-11 43.5 0.1 1.9 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE88091.1 - 1.1e-09 38.1 0.0 2e-09 37.2 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE88091.1 - 2e-06 27.5 0.0 3.2e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1777 PF08648.7 EIE88091.1 - 2.8 7.6 26.4 5 6.8 18.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) DUF3808 PF10300.4 EIE88092.1 - 3.6e-57 193.9 6.5 5.4e-57 193.3 4.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_12 PF13424.1 EIE88092.1 - 0.00041 20.2 2.6 3.8 7.5 0.2 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EIE88092.1 - 0.0048 16.7 10.2 2.1 8.4 0.1 4.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 EIE88092.1 - 0.0059 16.2 1.5 0.24 11.2 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 EIE88092.1 - 0.031 14.7 3.0 9.5 6.9 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 EIE88092.1 - 0.034 14.8 3.0 0.45 11.2 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 EIE88092.1 - 1.9 8.2 6.5 0.94 9.1 0.3 3.1 3 0 0 3 3 3 0 TPR repeat MRP-S25 PF13741.1 EIE88093.1 - 1e-28 100.3 0.2 1.1e-28 100.3 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 DUF1107 PF06526.7 EIE88093.1 - 0.0091 15.7 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1107) MRP-S23 PF10484.4 EIE88093.1 - 0.016 15.1 2.2 1.2 9.0 0.1 2.3 1 1 0 2 2 2 0 Mitochondrial ribosomal protein S23 DUF2457 PF10446.4 EIE88093.1 - 0.03 13.0 0.1 0.03 13.0 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) HECT PF00632.20 EIE88094.1 - 5.3e-68 229.5 0.0 9.4e-68 228.6 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) PFK PF00365.15 EIE88095.1 - 1.4e-156 519.6 12.6 4e-86 288.4 0.3 3.1 2 1 1 3 3 3 3 Phosphofructokinase Glyoxalase_2 PF12681.2 EIE88095.1 - 2.8e-06 27.9 0.0 2.3e-05 24.9 0.0 2.5 2 0 0 2 2 2 1 Glyoxalase-like domain DUF4646 PF15496.1 EIE88095.1 - 0.1 12.6 0.0 0.34 10.9 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4646) WD40 PF00400.27 EIE88096.1 - 1.2e-49 164.5 4.5 1.2e-10 40.8 0.3 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat F-box PF00646.28 EIE88096.1 - 8.3e-07 28.5 0.1 2.2e-06 27.1 0.1 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EIE88096.1 - 0.0002 20.9 0.3 0.00042 19.9 0.2 1.5 1 0 0 1 1 1 1 F-box-like PQQ_3 PF13570.1 EIE88096.1 - 0.00067 19.8 1.1 0.61 10.4 0.0 3.4 3 0 0 3 3 3 1 PQQ-like domain PQQ_2 PF13360.1 EIE88096.1 - 0.0049 16.3 0.0 2.2 7.6 0.0 2.3 2 0 0 2 2 2 2 PQQ-like domain Nucleoporin_N PF08801.6 EIE88096.1 - 0.045 12.5 0.1 14 4.2 0.0 3.6 1 1 1 4 4 4 0 Nup133 N terminal like Mito_carr PF00153.22 EIE88097.1 - 1.5e-68 226.5 2.7 2.5e-23 81.5 0.1 3.7 2 1 1 3 3 3 3 Mitochondrial carrier protein DUF221 PF02714.10 EIE88099.1 - 4.2e-75 252.5 24.0 5.6e-75 252.1 16.6 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF221 Tropomyosin_1 PF12718.2 EIE88099.1 - 1.4e-16 60.5 24.5 3e-15 56.2 17.0 2.1 1 1 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 EIE88099.1 - 1.5e-10 40.5 19.3 2.4e-10 39.8 13.4 1.2 1 0 0 1 1 1 1 Tropomyosin Nup54 PF13874.1 EIE88099.1 - 0.093 12.3 14.0 0.16 11.5 9.7 1.3 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 ERM PF00769.14 EIE88099.1 - 0.5 9.8 30.9 0.032 13.7 16.3 2.0 2 0 0 2 2 2 0 Ezrin/radixin/moesin family DUF342 PF03961.8 EIE88099.1 - 1.1 7.6 16.3 0.047 12.1 3.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) APG6 PF04111.7 EIE88099.1 - 1.1 8.1 21.3 2.1 7.3 14.7 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF641 PF04859.7 EIE88099.1 - 1.2 8.9 15.9 0.11 12.3 3.2 2.5 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Laminin_II PF06009.7 EIE88099.1 - 1.6 8.5 11.8 2.5 7.8 6.4 2.1 1 1 1 2 2 2 0 Laminin Domain II Med9 PF07544.8 EIE88099.1 - 5.1 6.9 14.9 7.3 6.4 1.8 2.6 1 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Pkinase PF00069.20 EIE88100.1 - 4.1e-39 134.3 0.2 6.1e-39 133.7 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE88100.1 - 2.7e-16 59.4 0.1 3.7e-16 58.9 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIE88100.1 - 0.00033 20.4 0.1 0.00082 19.1 0.1 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EIE88100.1 - 0.019 13.8 0.1 0.036 12.9 0.1 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 tRNA_Me_trans PF03054.11 EIE88101.1 - 9.6e-116 386.2 0.0 1.1e-115 386.0 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase ThiI PF02568.9 EIE88101.1 - 0.00012 21.5 0.0 0.00018 21.0 0.0 1.2 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) Asn_synthase PF00733.16 EIE88101.1 - 0.0022 17.5 0.0 0.0033 16.9 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase NAD_synthase PF02540.12 EIE88101.1 - 0.0082 15.0 0.0 0.015 14.2 0.0 1.4 1 0 0 1 1 1 1 NAD synthase Motile_Sperm PF00635.21 EIE88102.1 - 5.1e-18 64.7 2.8 4.2e-17 61.7 2.0 1.9 1 1 0 1 1 1 1 MSP (Major sperm protein) domain Tubulin PF00091.20 EIE88103.1 - 3.6e-72 242.7 0.0 4.7e-72 242.3 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EIE88103.1 - 4e-49 165.8 0.0 6.3e-49 165.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EIE88103.1 - 0.00035 20.0 0.0 0.0006 19.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Porin_3 PF01459.17 EIE88104.1 - 5.9e-52 176.6 5.1 6.6e-52 176.4 3.5 1.0 1 0 0 1 1 1 1 Eukaryotic porin NSP13 PF06460.7 EIE88105.1 - 0.12 11.2 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Coronavirus NSP13 Acyl-CoA_dh_1 PF00441.19 EIE88106.1 - 8.5e-33 113.5 0.3 1.3e-32 112.9 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.23 EIE88106.1 - 1.5e-21 75.9 0.1 3.2e-21 74.8 0.1 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.14 EIE88106.1 - 2e-18 65.6 0.1 4.2e-18 64.5 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EIE88106.1 - 2.4e-08 34.5 0.0 3.7e-07 30.7 0.0 2.5 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EIE88106.1 - 0.00012 22.3 0.0 0.00022 21.4 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain NAD_binding_10 PF13460.1 EIE88108.1 - 4.5e-13 49.6 0.0 6.3e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EIE88108.1 - 7.9e-08 31.8 0.1 1.1e-07 31.3 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EIE88108.1 - 0.026 13.9 0.2 0.083 12.3 0.0 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family ACP_syn_III_C PF08541.5 EIE88108.1 - 0.1 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal WD40 PF00400.27 EIE88109.1 - 5e-10 38.8 3.6 0.48 10.3 0.1 5.4 5 1 0 5 5 5 4 WD domain, G-beta repeat PQQ PF01011.16 EIE88109.1 - 0.034 13.6 0.1 0.14 11.7 0.0 2.0 2 0 0 2 2 2 0 PQQ enzyme repeat PQQ_2 PF13360.1 EIE88109.1 - 0.049 13.0 0.0 0.089 12.2 0.0 1.4 1 1 0 1 1 1 0 PQQ-like domain UreD PF01774.12 EIE88110.1 - 5e-50 169.8 0.0 5.8e-50 169.6 0.0 1.0 1 0 0 1 1 1 1 UreD urease accessory protein Asp PF00026.18 EIE88111.1 - 5.4e-93 311.7 4.7 6.3e-93 311.4 3.3 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIE88111.1 - 1.8e-07 31.2 0.5 8.1e-05 22.6 0.2 3.1 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EIE88111.1 - 6.7e-07 29.7 0.9 0.0038 17.7 0.1 3.0 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 EIE88111.1 - 8.6e-06 25.3 0.2 0.001 18.6 0.2 2.5 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal DIM1 PF02966.11 EIE88112.1 - 9.4e-69 229.0 0.2 1.1e-68 228.8 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.15 EIE88112.1 - 1.2e-05 24.8 0.0 1.6e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EIE88112.1 - 0.023 14.7 0.3 0.039 14.0 0.2 1.5 1 1 0 1 1 1 0 Thioredoxin-like Thioredoxin_7 PF13899.1 EIE88112.1 - 0.071 13.1 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like UCH PF00443.24 EIE88115.1 - 6.9e-21 74.5 0.0 7.8e-21 74.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EIE88115.1 - 0.00018 21.0 0.0 0.00019 20.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DNA_RNApol_7kD PF03604.8 EIE88116.1 - 3.6e-18 64.7 3.9 4.8e-18 64.3 2.7 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit NinF PF05810.7 EIE88116.1 - 0.00046 19.9 0.1 0.00051 19.7 0.1 1.1 1 0 0 1 1 1 1 NinF protein DZR PF12773.2 EIE88116.1 - 0.0015 18.3 1.6 0.0031 17.2 1.2 1.5 1 1 0 1 1 1 1 Double zinc ribbon HypA PF01155.14 EIE88116.1 - 0.0028 17.3 0.4 0.003 17.2 0.3 1.1 1 0 0 1 1 1 1 Hydrogenase expression/synthesis hypA family DUF2197 PF09963.4 EIE88116.1 - 0.0032 17.3 4.1 0.54 10.2 0.1 2.1 1 1 1 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2197) zf-NADH-PPase PF09297.6 EIE88116.1 - 0.0076 15.7 3.5 0.029 13.8 2.4 1.8 1 1 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain Zn_ribbon_recom PF13408.1 EIE88116.1 - 0.011 15.9 2.0 0.098 12.9 0.2 2.1 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain zf-ISL3 PF14690.1 EIE88116.1 - 0.018 15.0 2.3 0.033 14.2 0.3 2.0 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 TFIIS_C PF01096.13 EIE88116.1 - 0.018 14.6 0.9 2.7 7.6 0.2 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) GFA PF04828.9 EIE88116.1 - 0.022 14.7 0.6 2.3 8.2 0.1 2.0 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme OrfB_Zn_ribbon PF07282.6 EIE88116.1 - 0.027 14.1 0.3 0.032 13.9 0.2 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain DUF2296 PF10058.4 EIE88116.1 - 0.034 13.8 1.0 0.6 9.8 0.0 2.1 1 1 1 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) GATA PF00320.22 EIE88116.1 - 0.036 13.4 1.8 0.38 10.1 0.0 2.2 1 1 1 2 2 2 0 GATA zinc finger A2L_zn_ribbon PF08792.5 EIE88116.1 - 0.048 13.1 1.1 6.5 6.3 0.0 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain Zn-ribbon_8 PF09723.5 EIE88116.1 - 0.061 13.2 3.3 0.23 11.4 2.3 1.9 1 1 0 1 1 1 0 Zinc ribbon domain zinc_ribbon_6 PF14599.1 EIE88116.1 - 0.069 12.9 2.7 3.7 7.4 0.2 2.2 1 1 1 2 2 2 0 Zinc-ribbon zf-ribbon_3 PF13248.1 EIE88116.1 - 0.11 11.7 0.4 11 5.4 0.0 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Cas_CXXC_CXXC PF09706.5 EIE88116.1 - 0.11 12.6 2.7 2.2 8.5 0.3 2.1 1 1 1 2 2 2 0 CRISPR-associated protein (Cas_CXXC_CXXC) Zn_Tnp_IS1595 PF12760.2 EIE88116.1 - 0.13 12.1 2.3 1.8 8.4 1.5 2.0 1 1 2 3 3 3 0 Transposase zinc-ribbon domain zf-trcl PF13451.1 EIE88116.1 - 0.14 11.7 5.2 1.3 8.7 0.5 2.2 1 1 1 2 2 2 0 Probable zinc-binding domain zinc_ribbon_2 PF13240.1 EIE88116.1 - 0.17 11.4 1.6 3.4 7.2 1.1 2.1 1 1 0 1 1 1 0 zinc-ribbon domain zf-dskA_traR PF01258.12 EIE88116.1 - 0.19 11.5 2.7 3.6 7.4 0.2 2.2 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger DUF951 PF06107.6 EIE88116.1 - 0.21 11.1 0.5 0.21 11.1 0.4 1.5 2 0 0 2 2 1 0 Bacterial protein of unknown function (DUF951) YhfH PF14149.1 EIE88116.1 - 0.22 11.3 1.9 4.7 7.0 0.1 2.2 2 0 0 2 2 2 0 YhfH-like protein Lar_restr_allev PF14354.1 EIE88116.1 - 0.23 11.8 1.4 9.9 6.5 0.1 2.1 1 1 1 2 2 2 0 Restriction alleviation protein Lar zf-Sec23_Sec24 PF04810.10 EIE88116.1 - 0.26 10.8 2.2 4.4 6.9 0.4 2.2 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Mu-like_Com PF10122.4 EIE88116.1 - 0.36 9.9 2.2 6.3 5.9 0.0 2.1 1 1 1 2 2 2 0 Mu-like prophage protein Com TF_Zn_Ribbon PF08271.7 EIE88116.1 - 0.4 10.0 2.3 4.5 6.6 1.7 2.0 1 1 1 2 2 2 0 TFIIB zinc-binding zf-HYPF PF07503.7 EIE88116.1 - 1.4 8.3 4.7 26 4.3 3.2 2.3 1 1 0 1 1 1 0 HypF finger Ribosomal_L44 PF00935.14 EIE88116.1 - 1.5 8.8 5.5 14 5.7 3.8 2.2 1 1 0 1 1 1 0 Ribosomal protein L44 Aldo_ket_red PF00248.16 EIE88118.1 - 3.2e-81 272.2 0.0 3.7e-81 272.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.16 EIE88119.1 - 1.2e-39 135.8 0.0 6.8e-20 71.0 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family IF-2B PF01008.12 EIE88120.1 - 1.9e-62 210.8 1.9 3.3e-62 210.0 1.3 1.4 1 1 0 1 1 1 1 Initiation factor 2 subunit family Metallophos PF00149.23 EIE88121.1 - 1.4e-45 155.1 0.2 1.7e-45 154.8 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Aa_trans PF01490.13 EIE88122.1 - 1.7e-57 194.8 24.9 2.1e-57 194.4 17.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Septin PF00735.13 EIE88123.1 - 3.7e-90 301.7 2.1 1.2e-66 224.5 0.3 2.1 1 1 1 2 2 2 2 Septin MMR_HSR1 PF01926.18 EIE88123.1 - 1.5e-06 28.1 0.0 3.1e-06 27.1 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EIE88123.1 - 2.1e-06 27.0 0.2 3.8e-06 26.1 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 EIE88123.1 - 5.2e-05 22.4 0.1 0.00011 21.4 0.0 1.5 1 1 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.22 EIE88123.1 - 0.00012 21.5 0.1 0.00023 20.6 0.1 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 EIE88123.1 - 0.0019 18.4 0.2 0.0033 17.7 0.2 1.6 1 1 0 1 1 1 1 ABC transporter NB-ARC PF00931.17 EIE88123.1 - 0.0034 16.2 0.2 0.0055 15.6 0.2 1.3 1 0 0 1 1 1 1 NB-ARC domain Ras PF00071.17 EIE88123.1 - 0.004 16.5 0.0 0.0079 15.5 0.0 1.5 1 0 0 1 1 1 1 Ras family AAA_10 PF12846.2 EIE88123.1 - 0.012 15.0 0.0 0.019 14.3 0.0 1.5 1 1 0 1 1 1 0 AAA-like domain IIGP PF05049.8 EIE88123.1 - 0.033 13.0 0.0 0.05 12.4 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Gtr1_RagA PF04670.7 EIE88123.1 - 0.078 12.0 0.1 0.21 10.7 0.1 1.8 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Dynamin_N PF00350.18 EIE88123.1 - 0.092 12.5 1.7 12 5.6 0.0 2.5 1 1 0 2 2 2 0 Dynamin family Miro PF08477.8 EIE88123.1 - 0.11 13.0 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein AAA_16 PF13191.1 EIE88123.1 - 0.12 12.3 0.0 0.46 10.4 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain R3H PF01424.17 EIE88124.1 - 6.8e-11 41.7 0.1 1.3e-10 40.8 0.1 1.5 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.12 EIE88124.1 - 2.2e-08 33.8 214.8 0.00025 20.9 10.6 14.1 13 2 1 14 14 14 9 NF-X1 type zinc finger Aldo_ket_red PF00248.16 EIE88125.1 - 2.2e-80 269.5 0.0 2.5e-80 269.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family IL1_propep PF02394.11 EIE88126.1 - 0.096 13.0 3.6 0.64 10.4 2.2 2.1 2 0 0 2 2 2 0 Interleukin-1 propeptide Aldo_ket_red PF00248.16 EIE88127.1 - 4.8e-76 255.2 0.1 6.1e-76 254.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ADH_zinc_N PF00107.21 EIE88128.1 - 7.1e-22 77.3 0.0 9e-22 77.0 0.0 1.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF3661 PF12400.3 EIE88129.1 - 4e-37 127.1 13.5 6.9e-37 126.4 9.3 1.4 1 0 0 1 1 1 1 Vaculolar membrane protein MULE PF10551.4 EIE88130.1 - 2.2e-05 24.5 0.2 4.9e-05 23.4 0.1 1.6 2 0 0 2 2 2 1 MULE transposase domain DDE_3 PF13358.1 EIE88131.1 - 1.4e-10 41.1 0.0 1.5e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.14 EIE88131.1 - 0.12 11.5 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease RVT_1 PF00078.22 EIE88132.1 - 1.7e-21 76.6 0.0 1.9e-21 76.4 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Mannitol_dh PF01232.18 EIE88134.1 - 0.58 10.1 11.8 0.17 11.8 1.9 2.6 1 1 1 2 2 2 0 Mannitol dehydrogenase Rossmann domain DUF3584 PF12128.3 EIE88134.1 - 1.8 5.7 48.0 2.3 5.4 33.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Reo_sigmaC PF04582.7 EIE88134.1 - 5.8 5.9 8.4 2.2 7.3 0.7 2.1 1 1 0 2 2 2 0 Reovirus sigma C capsid protein LEA_2 PF03168.8 EIE88135.1 - 0.00038 20.7 0.1 0.00052 20.3 0.1 1.2 1 0 0 1 1 1 1 Late embryogenesis abundant protein BRI3BP PF14965.1 EIE88135.1 - 0.085 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Negative regulator of p53/TP53 DUF2897 PF11446.3 EIE88135.1 - 4 7.3 6.6 6.8 6.6 4.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) PH PF00169.24 EIE88136.1 - 2.1e-21 76.0 0.9 2.1e-21 76.0 0.6 2.9 2 1 0 2 2 2 1 PH domain SAM_2 PF07647.12 EIE88136.1 - 1.3e-13 50.5 0.6 2.8e-13 49.5 0.1 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EIE88136.1 - 1.3e-10 41.2 0.2 1.3e-10 41.2 0.1 2.1 3 0 0 3 3 2 1 SAM domain (Sterile alpha motif) CH PF00307.26 EIE88136.1 - 1.5e-07 31.3 0.0 3.7e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 Calponin homology (CH) domain SH3_9 PF14604.1 EIE88136.1 - 1.8e-05 24.1 0.1 5.1e-05 22.7 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain Ste50p-SAM PF09235.5 EIE88136.1 - 8.7e-05 22.4 0.2 0.00023 21.1 0.1 1.7 1 0 0 1 1 1 1 Ste50p, sterile alpha motif PH_11 PF15413.1 EIE88136.1 - 0.00027 21.1 5.6 0.00027 21.1 3.9 3.7 3 1 0 3 3 3 1 Pleckstrin homology domain SH3_1 PF00018.23 EIE88136.1 - 0.00071 18.9 0.4 0.0016 17.7 0.3 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EIE88136.1 - 0.0021 17.4 0.2 0.005 16.2 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain PH_3 PF14593.1 EIE88136.1 - 0.0021 17.9 1.0 0.007 16.2 0.7 1.8 1 0 0 1 1 1 1 PH domain PH_9 PF15410.1 EIE88136.1 - 0.0043 17.1 0.2 0.017 15.2 0.1 2.1 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 EIE88136.1 - 0.0086 16.1 1.4 0.048 13.7 1.0 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain SAM_PNT PF02198.11 EIE88136.1 - 0.026 14.2 0.3 0.13 12.0 0.0 2.1 2 0 0 2 2 2 0 Sterile alpha motif (SAM)/Pointed domain Pkinase PF00069.20 EIE88137.1 - 7e-53 179.4 0.6 1.8e-44 151.8 0.0 2.4 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIE88137.1 - 4.4e-17 62.0 0.1 5.3e-14 51.9 0.0 2.5 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EIE88137.1 - 0.00087 18.3 0.0 0.0064 15.4 0.0 2.0 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 EIE88137.1 - 0.011 15.5 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family EcKinase PF02958.15 EIE88137.1 - 0.024 13.8 0.1 0.033 13.3 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Mt_ATP-synt_B PF05405.9 EIE88137.1 - 0.07 12.5 0.1 0.13 11.7 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) YrbL-PhoP_reg PF10707.4 EIE88137.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Nfu_N PF08712.6 EIE88138.1 - 8e-31 105.5 0.0 1.5e-30 104.6 0.0 1.4 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 EIE88138.1 - 8.1e-23 79.9 0.1 1.2e-22 79.4 0.1 1.3 1 0 0 1 1 1 1 NifU-like domain Prefoldin_2 PF01920.15 EIE88139.1 - 1.9e-17 62.9 4.9 2.5e-17 62.5 3.4 1.2 1 0 0 1 1 1 1 Prefoldin subunit DivIC PF04977.10 EIE88139.1 - 0.0055 16.1 2.4 0.011 15.1 1.7 1.5 1 0 0 1 1 1 1 Septum formation initiator IFT20 PF14931.1 EIE88139.1 - 0.014 15.2 1.0 0.014 15.2 0.7 1.7 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 RNA_pol_Rpb1_6 PF04992.9 EIE88139.1 - 0.02 14.6 1.1 0.024 14.3 0.8 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 6 Rep_1 PF01446.12 EIE88139.1 - 0.028 13.7 0.9 0.035 13.4 0.6 1.1 1 0 0 1 1 1 0 Replication protein HALZ PF02183.13 EIE88139.1 - 0.035 13.8 1.2 0.035 13.8 0.8 2.3 3 0 0 3 3 3 0 Homeobox associated leucine zipper Tn7_Tnp_TnsA_N PF08722.6 EIE88139.1 - 0.1 12.6 0.5 0.15 12.0 0.3 1.4 1 0 0 1 1 1 0 TnsA endonuclease N terminal Acetyltransf_8 PF13523.1 EIE88139.1 - 0.15 11.9 0.3 0.5 10.2 0.2 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain V_ATPase_I PF01496.14 EIE88139.1 - 0.57 7.9 2.3 0.54 8.0 1.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_23 PF13476.1 EIE88139.1 - 0.58 10.4 4.4 0.61 10.3 3.0 1.1 1 0 0 1 1 1 0 AAA domain TMF_DNA_bd PF12329.3 EIE88139.1 - 7.8 6.3 8.7 0.55 10.0 1.4 2.2 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding PH PF00169.24 EIE88142.1 - 5.6e-25 87.5 6.7 1e-12 48.1 1.3 2.8 3 0 0 3 3 3 2 PH domain PH_11 PF15413.1 EIE88142.1 - 5.5e-12 45.9 5.5 1.8e-06 28.1 0.0 3.2 2 1 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.1 EIE88142.1 - 5.7e-09 35.9 2.3 0.0015 18.5 0.0 2.4 2 0 0 2 2 2 2 Pleckstrin homology domain PH_3 PF14593.1 EIE88142.1 - 1.3e-06 28.2 5.7 0.00041 20.1 2.7 2.4 2 0 0 2 2 2 2 PH domain PH_9 PF15410.1 EIE88142.1 - 0.023 14.8 11.2 0.68 10.1 4.1 3.5 2 2 1 3 3 3 0 Pleckstrin homology domain PH_7 PF15408.1 EIE88142.1 - 0.16 11.8 1.0 14 5.6 0.1 2.5 2 1 0 2 2 2 0 Pleckstrin homology domain PBP1_TM PF14812.1 EIE88142.1 - 0.27 11.5 0.1 0.27 11.5 0.1 3.6 4 0 0 4 4 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Glyco_hydro_38C PF07748.8 EIE88143.1 - 1.4e-80 271.3 0.0 2e-80 270.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Glyco_hydro_38 PF01074.17 EIE88143.1 - 4.1e-55 186.9 1.1 3.7e-26 91.9 1.1 2.5 2 0 0 2 2 2 2 Glycosyl hydrolases family 38 N-terminal domain Alpha-mann_mid PF09261.6 EIE88143.1 - 3e-22 78.6 0.0 8.7e-22 77.1 0.0 1.8 1 0 0 1 1 1 1 Alpha mannosidase, middle domain AAA PF00004.24 EIE88144.1 - 3.1e-15 56.5 0.0 6.4e-15 55.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EIE88144.1 - 1.2e-09 38.3 0.0 2.5e-09 37.3 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EIE88144.1 - 7.6e-09 35.7 0.0 1.5e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EIE88144.1 - 1.4e-05 24.9 0.0 3.2e-05 23.7 0.0 1.6 1 1 1 2 2 2 1 Archaeal ATPase NACHT PF05729.7 EIE88144.1 - 3.3e-05 23.5 0.0 0.00014 21.5 0.0 2.0 2 0 0 2 2 2 1 NACHT domain DUF2075 PF09848.4 EIE88144.1 - 4.8e-05 22.4 0.0 8.9e-05 21.6 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 EIE88144.1 - 0.00017 21.2 0.0 0.00055 19.6 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain Cdc6_C PF09079.6 EIE88144.1 - 0.00022 20.8 0.0 0.00052 19.6 0.0 1.7 1 0 0 1 1 1 1 CDC6, C terminal AAA_14 PF13173.1 EIE88144.1 - 0.00029 20.7 0.0 0.00084 19.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EIE88144.1 - 0.0018 18.5 0.0 0.0047 17.2 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_11 PF13086.1 EIE88144.1 - 0.0022 17.5 0.3 0.0038 16.8 0.2 1.6 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EIE88144.1 - 0.0043 17.8 0.0 0.019 15.7 0.0 2.0 2 1 0 2 2 2 1 AAA domain UvrD-helicase PF00580.16 EIE88144.1 - 0.016 14.5 0.0 0.039 13.2 0.0 1.6 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain NTPase_1 PF03266.10 EIE88144.1 - 0.019 14.6 0.0 0.064 12.9 0.0 1.9 1 0 0 1 1 1 0 NTPase RNA_helicase PF00910.17 EIE88144.1 - 0.026 14.6 0.0 0.1 12.7 0.0 2.1 2 0 0 2 2 2 0 RNA helicase ArgK PF03308.11 EIE88144.1 - 0.036 12.8 0.1 0.48 9.1 0.0 2.3 2 0 0 2 2 2 0 ArgK protein KAP_NTPase PF07693.9 EIE88144.1 - 0.069 12.1 0.1 1.7 7.5 0.0 2.1 1 1 1 2 2 2 0 KAP family P-loop domain SspH PF08141.7 EIE88144.1 - 0.74 9.9 3.9 16 5.6 0.0 3.2 3 0 0 3 3 3 0 Small acid-soluble spore protein H family DUF943 PF06092.7 EIE88145.1 - 0.05 12.8 0.1 0.098 11.9 0.0 1.4 1 0 0 1 1 1 0 Enterobacterial putative membrane protein (DUF943) Autoind_synth PF00765.12 EIE88148.1 - 0.0082 15.4 0.0 0.01 15.0 0.0 1.2 1 0 0 1 1 1 1 Autoinducer synthetase HTH_Tnp_Tc5 PF03221.11 EIE88150.1 - 5.9e-05 22.8 0.0 9.7e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CPSase_sm_chain PF00988.17 EIE88151.1 - 2.6e-47 159.5 0.0 3.8e-47 159.0 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 EIE88151.1 - 7.5e-41 139.6 0.0 1.1e-40 139.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EIE88151.1 - 0.00012 21.6 0.4 0.033 13.6 0.3 2.8 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.19 EIE88151.1 - 0.089 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 DJ-1/PfpI family Dynactin PF12455.3 EIE88152.1 - 7.3e-70 235.0 11.6 7.3e-70 235.0 8.1 3.2 4 0 0 4 4 4 1 Dynein associated protein CAP_GLY PF01302.20 EIE88152.1 - 1.5e-23 82.2 1.2 2.7e-23 81.4 0.8 1.4 1 0 0 1 1 1 1 CAP-Gly domain Hydrolase_like PF13242.1 EIE88152.1 - 2.3e-08 33.6 0.0 5.5e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like HAMP PF00672.20 EIE88152.1 - 0.19 11.9 1.4 1.7 8.9 0.4 2.8 2 0 0 2 2 2 0 HAMP domain Pro_isomerase PF00160.16 EIE88153.1 - 2.9e-47 160.7 0.1 3.2e-47 160.6 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 3-HAO PF06052.7 EIE88155.1 - 3.1e-52 176.0 0.3 3.8e-52 175.7 0.2 1.1 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase HMG_box PF00505.14 EIE88156.1 - 2.2e-20 72.7 4.8 2.2e-20 72.7 3.4 2.1 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EIE88156.1 - 4.5e-10 39.7 5.8 1.3e-09 38.2 2.6 2.4 2 0 0 2 2 2 1 HMG-box domain Rota_VP2 PF05087.7 EIE88156.1 - 0.061 11.2 2.8 0.077 10.9 1.9 1.1 1 0 0 1 1 1 0 Rotavirus VP2 protein DDE_3 PF13358.1 EIE88158.1 - 0.0071 16.1 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease MARVEL PF01284.18 EIE88160.1 - 0.00019 21.2 4.9 0.00029 20.6 3.4 1.3 1 0 0 1 1 1 1 Membrane-associating domain SUR7 PF06687.7 EIE88160.1 - 0.0088 15.6 2.8 0.0083 15.7 1.3 1.4 1 1 0 1 1 1 1 SUR7/PalI family DUF3180 PF11377.3 EIE88160.1 - 0.013 15.3 0.1 0.61 9.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3180) DsbD_2 PF13386.1 EIE88160.1 - 0.019 14.6 3.1 0.84 9.3 1.0 2.1 2 0 0 2 2 2 0 Cytochrome C biogenesis protein transmembrane region DUF308 PF03729.8 EIE88160.1 - 0.028 14.3 16.2 0.035 14.0 1.3 2.5 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) EI24 PF07264.6 EIE88160.1 - 0.042 13.2 4.6 0.067 12.6 3.1 1.4 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) COPI_assoc PF08507.5 EIE88160.1 - 0.05 13.2 0.0 0.05 13.2 0.0 2.5 2 1 0 2 2 2 0 COPI associated protein Renin_r PF07850.9 EIE88160.1 - 0.053 13.8 3.1 0.14 12.4 0.3 2.2 2 0 0 2 2 2 0 Renin receptor-like protein PIRT PF15099.1 EIE88160.1 - 0.066 12.4 0.1 0.13 11.4 0.1 1.5 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family E1-E2_ATPase PF00122.15 EIE88160.1 - 0.079 11.9 0.7 2.3 7.2 0.0 2.1 2 0 0 2 2 2 0 E1-E2 ATPase Ost4 PF10215.4 EIE88160.1 - 0.13 11.8 3.0 0.31 10.5 2.1 1.7 1 0 0 1 1 1 0 Oligosaccaryltransferase Claudin_2 PF13903.1 EIE88160.1 - 0.13 11.9 6.7 0.75 9.4 3.2 2.1 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF2422 PF10337.4 EIE88160.1 - 0.27 9.9 0.0 0.27 9.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2422) DUF3487 PF11990.3 EIE88160.1 - 0.33 10.3 3.7 19 4.6 1.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) DUF4282 PF14110.1 EIE88160.1 - 0.36 11.0 13.1 1.4 9.1 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) Pox_I5 PF04713.7 EIE88160.1 - 0.45 10.2 5.6 0.18 11.5 0.5 2.3 2 0 0 2 2 2 0 Poxvirus protein I5 Tetraspannin PF00335.15 EIE88160.1 - 0.51 9.5 16.5 0.13 11.4 4.9 2.1 1 1 2 3 3 3 0 Tetraspanin family FtsX PF02687.16 EIE88160.1 - 0.58 9.9 12.0 2.4 7.9 0.8 3.0 2 1 1 3 3 3 0 FtsX-like permease family NfeD PF01957.13 EIE88160.1 - 0.98 9.5 6.9 3.6 7.7 2.7 2.1 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding PIG-P PF08510.7 EIE88160.1 - 1.4 8.6 4.2 0.28 10.8 0.2 1.8 2 0 0 2 2 2 0 PIG-P DUF2232 PF09991.4 EIE88160.1 - 1.7 7.5 10.1 11 4.8 5.2 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2232) RDD PF06271.7 EIE88160.1 - 1.9 8.3 6.8 6.1 6.7 2.3 2.1 2 0 0 2 2 2 0 RDD family SNARE PF05739.14 EIE88161.1 - 3.9e-16 58.4 5.1 3.9e-16 58.4 3.6 2.9 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 EIE88161.1 - 1.6e-07 31.4 12.5 2e-07 31.1 0.7 3.3 2 1 0 3 3 3 1 Syntaxin Syntaxin_2 PF14523.1 EIE88161.1 - 0.027 14.5 8.9 0.039 13.9 1.5 2.5 2 0 0 2 2 2 0 Syntaxin-like protein Vasculin PF15337.1 EIE88161.1 - 0.042 14.3 0.2 0.086 13.3 0.2 1.6 1 0 0 1 1 1 0 Vascular protein family Vasculin-like 1 FliG_N PF14842.1 EIE88161.1 - 0.089 12.9 6.0 1.1 9.4 0.1 3.0 3 0 0 3 3 3 0 FliG N-terminal domain BRE1 PF08647.6 EIE88161.1 - 0.33 10.9 7.6 2.9 7.9 0.1 2.4 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase H-kinase_dim PF02895.9 EIE88161.1 - 2.2 8.7 8.5 59 4.1 4.7 3.2 1 1 1 2 2 2 0 Signal transducing histidine kinase, homodimeric domain MCPsignal PF00015.16 EIE88161.1 - 2.4 7.6 16.5 0.06 12.8 1.1 2.7 2 1 1 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF2203 PF09969.4 EIE88161.1 - 5.5 7.2 6.3 65 3.7 3.5 2.6 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Got1 PF04178.7 EIE88162.1 - 7.8e-22 77.6 8.4 9.2e-22 77.3 5.8 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family DUF1109 PF06532.6 EIE88162.1 - 0.0079 15.6 1.7 0.0079 15.6 1.2 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1109) HOOK PF05622.7 EIE88163.1 - 1.1e-12 46.6 50.5 1.2e-09 36.6 11.5 3.7 1 1 0 2 2 2 2 HOOK protein DUF3897 PF13036.1 EIE88163.1 - 0.0091 15.6 1.6 3.1 7.3 0.6 2.8 1 1 1 2 2 2 2 Protein of unknown function (DUF3897) YjcQ PF09639.5 EIE88163.1 - 0.052 13.6 1.8 0.13 12.3 0.1 2.6 2 1 1 3 3 3 0 YjcQ protein HALZ PF02183.13 EIE88163.1 - 0.11 12.2 0.1 0.11 12.2 0.1 6.3 6 1 0 6 6 6 0 Homeobox associated leucine zipper Filament PF00038.16 EIE88163.1 - 1.4 8.3 48.9 0.29 10.5 25.1 2.4 1 1 1 2 2 2 0 Intermediate filament protein V-SNARE_C PF12352.3 EIE88163.1 - 1.4 9.0 14.2 0.93 9.6 0.2 4.4 3 2 0 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus Spc7 PF08317.6 EIE88163.1 - 2 7.0 46.2 0.0068 15.0 10.2 3.3 1 1 2 3 3 3 0 Spc7 kinetochore protein Reo_sigmaC PF04582.7 EIE88163.1 - 2.7 7.1 10.2 1.6 7.8 0.9 2.8 2 1 0 3 3 3 0 Reovirus sigma C capsid protein DUF349 PF03993.7 EIE88163.1 - 9.9 6.4 12.0 10 6.3 0.8 3.3 3 0 0 3 3 3 0 Domain of Unknown Function (DUF349) UvrD_C PF13361.1 EIE88164.1 - 1.2e-74 251.8 0.2 1.2e-74 251.8 0.1 4.2 3 1 0 4 4 4 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 EIE88164.1 - 9.3e-63 212.4 6.7 9.3e-63 212.4 4.6 3.7 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.1 EIE88164.1 - 4.1e-12 45.6 0.1 9.8e-12 44.4 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain UvrD_C_2 PF13538.1 EIE88164.1 - 2e-09 37.5 0.0 2.2e-08 34.1 0.0 2.8 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.1 EIE88164.1 - 0.00043 19.9 0.3 0.057 12.9 0.0 2.8 3 0 0 3 3 3 1 AAA domain RVT_1 PF00078.22 EIE88165.1 - 7.3e-08 32.0 0.0 1.1e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HNH PF01844.18 EIE88167.1 - 0.061 13.2 0.4 0.12 12.3 0.3 1.5 1 0 0 1 1 1 0 HNH endonuclease Glyco_transf_64 PF09258.5 EIE88168.1 - 7.9e-51 172.5 0.4 1e-50 172.2 0.3 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain DUF3822 PF12864.2 EIE88168.1 - 0.0031 16.7 1.1 0.0045 16.2 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3822) Proteasome PF00227.21 EIE88171.1 - 8.9e-62 207.7 0.3 1.3e-61 207.2 0.2 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EIE88171.1 - 5.2e-14 51.2 0.1 1e-13 50.3 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature IL6 PF00489.12 EIE88171.1 - 0.1 12.2 1.1 0.2 11.2 0.4 1.7 2 0 0 2 2 2 0 Interleukin-6/G-CSF/MGF family HSP70 PF00012.15 EIE88172.1 - 1.2e-09 36.6 0.0 7.8e-09 33.9 0.0 1.9 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EIE88172.1 - 0.015 13.9 0.0 0.42 9.1 0.0 2.2 2 0 0 2 2 2 0 MreB/Mbl protein HOOK PF05622.7 EIE88173.1 - 3.3e-41 140.9 89.4 4.5e-30 104.1 10.8 3.1 1 1 2 3 3 3 3 HOOK protein MTS PF05175.9 EIE88175.1 - 3.9e-11 42.6 0.0 5.7e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 EIE88175.1 - 1.1e-10 41.1 0.0 1.5e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 EIE88175.1 - 1.4e-08 34.7 0.0 1.9e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 EIE88175.1 - 1.8e-07 30.8 0.0 2.4e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_31 PF13847.1 EIE88175.1 - 5.9e-07 29.1 0.2 7.6e-07 28.8 0.2 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIE88175.1 - 6.2e-07 29.9 0.0 8.9e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 EIE88175.1 - 3.2e-05 23.5 0.0 5e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.10 EIE88175.1 - 0.0011 18.4 0.0 0.0014 18.0 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein 95 DUF43 PF01861.11 EIE88175.1 - 0.0044 16.0 0.0 0.0044 16.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF43 Methyltransf_25 PF13649.1 EIE88175.1 - 0.008 16.5 0.0 0.016 15.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain DUF3303 PF11746.3 EIE88175.1 - 0.01 16.1 0.0 0.028 14.7 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3303) Methyltransf_12 PF08242.7 EIE88175.1 - 0.011 16.2 0.0 0.023 15.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain N6_Mtase PF02384.11 EIE88175.1 - 0.034 13.2 0.0 0.045 12.8 0.0 1.3 1 0 0 1 1 1 0 N-6 DNA Methylase Methyltransf_23 PF13489.1 EIE88175.1 - 0.059 13.0 0.0 0.073 12.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Fer4_2 PF12797.2 EIE88176.1 - 7.6 6.6 7.5 4.6 7.3 1.8 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain HSP70 PF00012.15 EIE88177.1 - 7.9e-273 905.8 8.6 9e-273 905.6 6.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EIE88177.1 - 7.7e-17 60.8 0.1 3e-15 55.6 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 EIE88177.1 - 0.0028 17.3 0.0 0.012 15.2 0.0 2.1 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 EIE88177.1 - 0.038 13.0 2.9 0.054 12.5 0.1 2.5 2 1 1 3 3 3 0 Hydantoinase/oxoprolinase Not1 PF04054.10 EIE88180.1 - 5e-142 473.2 3.1 1.2e-141 471.9 2.2 1.8 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 EIE88180.1 - 1.7e-49 167.3 4.8 1.7e-49 167.3 3.3 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF3819) Sec2p PF06428.6 EIE88181.1 - 4.1e-12 45.8 20.0 4.1e-12 45.8 13.9 1.8 1 1 0 1 1 1 1 GDP/GTP exchange factor Sec2p V_ATPase_I PF01496.14 EIE88181.1 - 0.0032 15.4 12.5 0.0038 15.1 8.6 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Exonuc_VII_L PF02601.10 EIE88181.1 - 0.018 14.2 13.3 0.027 13.6 9.2 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Atg14 PF10186.4 EIE88181.1 - 0.022 13.6 16.6 0.04 12.8 11.5 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 CAF-1_p150 PF11600.3 EIE88181.1 - 0.022 14.1 15.1 0.033 13.5 10.4 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF342 PF03961.8 EIE88181.1 - 0.054 11.8 7.8 0.079 11.3 5.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF3584 PF12128.3 EIE88181.1 - 0.06 10.6 18.1 0.078 10.3 12.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) YqaJ PF09588.5 EIE88181.1 - 0.13 12.1 1.5 0.18 11.7 1.0 1.2 1 0 0 1 1 1 0 YqaJ-like viral recombinase domain IFT57 PF10498.4 EIE88181.1 - 0.25 10.0 16.7 0.36 9.5 11.6 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Spc7 PF08317.6 EIE88181.1 - 0.31 9.6 18.4 0.62 8.6 12.7 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4407 PF14362.1 EIE88181.1 - 0.37 9.7 8.7 0.53 9.1 6.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) UPF0449 PF15136.1 EIE88181.1 - 1.1 9.5 16.3 2 8.6 4.7 2.5 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 Tropomyosin_1 PF12718.2 EIE88181.1 - 1.2 8.9 26.9 2.1 8.2 18.7 1.3 1 0 0 1 1 1 0 Tropomyosin like YgaB PF14182.1 EIE88181.1 - 3 8.1 15.9 0.16 12.1 3.2 2.7 1 1 1 2 2 2 0 YgaB-like protein Peptidase_S46 PF10459.4 EIE88181.1 - 5.4 5.2 10.6 6.9 4.9 7.4 1.1 1 0 0 1 1 1 0 Peptidase S46 APG6 PF04111.7 EIE88181.1 - 5.8 5.8 23.5 8.4 5.3 15.7 1.6 1 1 1 2 2 2 0 Autophagy protein Apg6 TH1 PF04858.8 EIE88182.1 - 2.1e-15 55.9 1.3 6.3e-11 41.1 0.3 2.0 2 0 0 2 2 2 2 TH1 protein TH1 PF04858.8 EIE88183.1 - 1.5e-21 76.1 0.0 1.8e-21 75.9 0.0 1.0 1 0 0 1 1 1 1 TH1 protein ArfGap PF01412.13 EIE88184.1 - 3.7e-31 107.3 0.1 3.7e-31 107.3 0.1 2.3 2 1 0 2 2 2 1 Putative GTPase activating protein for Arf UBA PF00627.26 EIE88184.1 - 5.8e-07 29.1 0.2 3.6e-06 26.6 0.0 2.2 2 0 0 2 2 2 1 UBA/TS-N domain XG_FTase PF03254.8 EIE88185.1 - 0.00066 18.3 0.0 0.0021 16.6 0.0 1.7 2 0 0 2 2 2 1 Xyloglucan fucosyltransferase VAD1-2 PF15310.1 EIE88185.1 - 0.14 11.8 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Vitamin A-deficiency (VAD) rat model signalling DUF3689 PF12463.3 EIE88186.1 - 0.017 13.8 0.1 0.017 13.8 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3689) BTB PF00651.26 EIE88187.1 - 1.8e-08 34.3 0.1 3.5e-08 33.4 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain Kelch_6 PF13964.1 EIE88187.1 - 2.3e-07 30.6 1.9 0.0012 18.8 0.0 3.8 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 EIE88187.1 - 3.7e-07 29.6 0.1 1.7e-06 27.5 0.0 2.2 1 0 0 1 1 1 1 Kelch motif Kelch_5 PF13854.1 EIE88187.1 - 8.1e-07 28.8 0.3 0.13 12.2 0.0 3.4 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 EIE88187.1 - 1.3e-05 24.8 0.0 0.063 13.0 0.0 2.8 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_1 PF01344.20 EIE88187.1 - 0.00052 19.5 0.3 0.0013 18.2 0.2 1.7 1 0 0 1 1 1 1 Kelch motif DUF2738 PF10927.3 EIE88187.1 - 0.0014 17.7 0.2 0.0025 16.8 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2738) Kelch_3 PF13415.1 EIE88187.1 - 0.056 13.6 0.1 7.9 6.7 0.0 3.6 3 0 0 3 3 3 0 Galactose oxidase, central domain TRAPP PF04051.11 EIE88188.1 - 3.5e-46 156.4 0.0 4e-46 156.2 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component LT-IIB PF06453.6 EIE88188.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Type II heat-labile enterotoxin , B subunit (LT-IIB) Yip1 PF04893.12 EIE88189.1 - 2.3e-17 63.0 16.0 3.8e-17 62.3 11.1 1.3 1 1 0 1 1 1 1 Yip1 domain RNA_polI_A34 PF08208.6 EIE88191.1 - 2.2e-11 43.7 0.0 4.4e-11 42.8 0.0 1.5 1 1 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 ubiquitin PF00240.18 EIE88192.1 - 9.2e-12 44.1 0.0 9.9e-12 44.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.1 EIE88192.1 - 0.00088 19.1 0.0 0.00088 19.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD PF11976.3 EIE88192.1 - 0.0022 17.6 0.0 0.0026 17.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EIE88192.1 - 0.021 14.9 0.0 0.021 14.9 0.0 1.1 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain DUF2362 PF10154.4 EIE88193.1 - 2.4e-48 165.0 46.1 6.2e-39 134.0 6.8 5.2 2 1 1 3 3 3 2 Uncharacterized conserved protein (DUF2362) UBA PF00627.26 EIE88193.1 - 7.9e-06 25.5 0.1 7.9e-06 25.5 0.1 2.0 2 0 0 2 2 2 1 UBA/TS-N domain Ndc1_Nup PF09531.5 EIE88193.1 - 0.18 10.1 11.3 0.31 9.3 7.8 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TSA PF03249.8 EIE88193.1 - 3 6.2 12.6 4.6 5.6 8.7 1.2 1 0 0 1 1 1 0 Type specific antigen DUF775 PF05603.7 EIE88193.1 - 4.2 6.8 15.1 13 5.2 10.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF775) Polysacc_deac_1 PF01522.16 EIE88197.1 - 3.7e-36 123.4 0.0 7.1e-36 122.5 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 EIE88197.1 - 0.0026 16.7 1.0 0.016 14.1 0.0 1.9 1 1 1 2 2 2 1 Glycosyl hydrolase family 57 zf-met2 PF12907.2 EIE88198.1 - 6.6e-14 51.5 9.8 2.2e-13 49.9 6.8 1.9 1 1 0 1 1 1 1 Zinc-binding 4F5 PF04419.9 EIE88198.1 - 0.00082 20.0 12.3 0.00082 20.0 8.6 2.0 2 1 0 2 2 2 1 4F5 protein family DUF2296 PF10058.4 EIE88198.1 - 0.11 12.2 0.2 0.17 11.6 0.2 1.4 1 0 0 1 1 1 0 Predicted integral membrane metal-binding protein (DUF2296) DUF4451 PF14616.1 EIE88198.1 - 0.19 11.5 4.3 0.22 11.2 3.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4451) Rpr2 PF04032.11 EIE88198.1 - 0.62 9.9 4.2 0.8 9.6 2.9 1.3 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-Di19 PF05605.7 EIE88198.1 - 1.3 9.1 4.7 0.46 10.6 0.6 1.9 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DUF3340 PF11818.3 EIE88200.1 - 0.058 13.3 0.9 0.092 12.6 0.6 1.3 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) 3HCDH_N PF02737.13 EIE88202.1 - 1.3e-57 194.3 1.0 1.7e-57 194.0 0.7 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 EIE88202.1 - 8e-32 109.5 0.1 2.6e-31 107.8 0.0 1.9 2 1 1 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Pyr_redox_2 PF07992.9 EIE88202.1 - 0.00024 21.0 0.1 0.00034 20.5 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.10 EIE88202.1 - 0.00037 20.3 2.6 0.0051 16.6 1.8 2.2 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.16 EIE88202.1 - 0.00041 19.9 0.2 0.00077 19.0 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_Gly3P_dh_N PF01210.18 EIE88202.1 - 0.005 16.5 0.6 0.0098 15.6 0.4 1.6 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Saccharop_dh PF03435.13 EIE88202.1 - 0.027 13.4 0.2 0.037 12.9 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase YbaB_DNA_bd PF02575.11 EIE88202.1 - 0.029 14.2 2.1 0.065 13.1 0.3 2.4 2 1 0 3 3 3 0 YbaB/EbfC DNA-binding family DAO PF01266.19 EIE88202.1 - 0.029 13.2 0.0 0.037 12.9 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase TrkA_N PF02254.13 EIE88202.1 - 0.031 14.2 0.1 0.14 12.1 0.1 2.1 2 0 0 2 2 2 0 TrkA-N domain XdhC_C PF13478.1 EIE88202.1 - 0.035 14.4 0.0 0.055 13.7 0.0 1.5 1 1 0 1 1 1 0 XdhC Rossmann domain ApbA PF02558.11 EIE88202.1 - 0.04 13.3 0.0 0.068 12.6 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.12 EIE88202.1 - 0.053 13.9 1.6 0.16 12.3 1.1 1.9 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 EIE88202.1 - 0.083 12.9 0.7 2.1 8.4 0.0 2.5 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Ribosomal_L29e PF01779.12 EIE88203.1 - 2.2e-22 78.6 14.1 3.3e-22 78.0 9.8 1.3 1 0 0 1 1 1 1 Ribosomal L29e protein family Baculo_PEP_C PF04513.7 EIE88204.1 - 0.013 15.3 1.3 0.03 14.1 0.9 1.6 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus SlyX PF04102.7 EIE88204.1 - 0.041 14.2 0.5 0.041 14.2 0.4 2.7 3 0 0 3 3 3 0 SlyX Prefoldin PF02996.12 EIE88204.1 - 0.045 13.4 1.6 0.1 12.2 1.1 1.6 1 0 0 1 1 1 0 Prefoldin subunit PEP-utilisers_N PF05524.8 EIE88204.1 - 0.12 12.2 1.0 2.1 8.1 0.2 2.4 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal Fib_alpha PF08702.5 EIE88204.1 - 0.22 11.6 5.2 0.15 12.2 2.0 1.8 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Atg14 PF10186.4 EIE88204.1 - 0.26 10.1 5.7 0.13 11.2 2.1 1.9 2 1 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 YjcZ PF13990.1 EIE88204.1 - 0.28 10.2 2.2 0.21 10.6 0.5 1.5 2 0 0 2 2 2 0 YjcZ-like protein DUF4094 PF13334.1 EIE88204.1 - 1.3 9.4 5.9 5.1 7.5 2.4 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) Glyco_hydro_8 PF01270.12 EIE88206.1 - 7.6e-44 149.8 1.0 1.2e-43 149.1 0.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 8 DDE_3 PF13358.1 EIE88209.1 - 4.9e-14 52.3 0.0 5.6e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease RNase_HII PF01351.13 EIE88210.1 - 1.3 8.5 4.6 3.1 7.3 2.6 1.7 1 1 1 2 2 2 0 Ribonuclease HII Aminotran_1_2 PF00155.16 EIE88211.1 - 6e-56 189.9 0.0 7.3e-56 189.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EIE88211.1 - 1.8e-07 30.5 0.0 2.9e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 EIE88211.1 - 0.00011 20.5 0.2 0.00031 19.1 0.1 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 EIE88211.1 - 0.00014 21.1 0.0 0.00021 20.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EIE88211.1 - 0.00037 19.3 0.0 0.0079 14.9 0.0 2.1 2 0 0 2 2 2 1 Aminotransferase class-V Proteasom_PSMB PF10508.4 EIE88212.1 - 4.7e-36 124.1 7.1 7.9e-28 96.9 1.9 3.5 1 1 3 4 4 4 3 Proteasome non-ATPase 26S subunit RICTOR_M PF14666.1 EIE88212.1 - 0.0014 17.7 0.5 0.31 10.0 0.0 2.6 2 1 0 2 2 2 2 Rapamycin-insensitive companion of mTOR, middle domain BSD PF03909.12 EIE88213.1 - 2.2e-06 27.3 0.1 5.5e-06 26.0 0.1 1.7 1 0 0 1 1 1 1 BSD domain TFIIH_BTF_p62_N PF08567.6 EIE88213.1 - 2.4e-05 23.9 0.0 5e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain Pex14_N PF04695.8 EIE88213.1 - 0.069 13.1 5.3 0.17 11.9 3.7 1.7 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MSP1_C PF07462.6 EIE88213.1 - 1 7.6 4.5 1.6 6.9 3.1 1.4 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Herpes_BLLF1 PF05109.8 EIE88213.1 - 1.1 7.1 19.2 1.4 6.7 13.3 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) Mucin PF01456.12 EIE88213.1 - 3.7 7.3 25.9 6.6 6.4 17.9 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein SSP160 PF06933.6 EIE88213.1 - 6.6 4.5 14.9 8.5 4.2 10.3 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 WH1 PF00568.18 EIE88214.1 - 1.2e-16 60.3 0.8 2e-16 59.7 0.5 1.3 1 0 0 1 1 1 1 WH1 domain PBD PF00786.23 EIE88214.1 - 1.6e-07 31.6 0.7 3.6e-07 30.4 0.1 1.9 2 0 0 2 2 2 1 P21-Rho-binding domain Gly-zipper_OmpA PF13436.1 EIE88214.1 - 0.011 15.4 2.6 0.021 14.4 1.8 1.5 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Shadoo PF14999.1 EIE88214.1 - 0.017 14.9 5.7 0.027 14.3 3.9 1.2 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective WH2 PF02205.15 EIE88214.1 - 0.054 13.1 0.2 0.14 11.7 0.1 1.8 1 0 0 1 1 1 0 WH2 motif Nif11 PF07862.6 EIE88214.1 - 0.073 13.0 0.4 0.15 11.9 0.3 1.6 1 0 0 1 1 1 0 Nitrogen fixation protein of unknown function FERM_N PF09379.5 EIE88215.1 - 0.025 14.6 0.4 0.075 13.0 0.1 1.8 1 1 1 2 2 2 0 FERM N-terminal domain tRNA-synt_1c_C PF03950.13 EIE88215.1 - 0.033 13.8 0.2 0.038 13.6 0.1 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), anti-codon binding domain YueH PF14166.1 EIE88217.1 - 0.023 14.4 0.0 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 YueH-like protein YTH PF04146.10 EIE88218.1 - 0.079 12.5 0.0 0.13 11.8 0.0 1.4 1 1 0 1 1 1 0 YT521-B-like domain Exo_endo_phos PF03372.18 EIE88219.1 - 1.3e-14 54.7 0.2 2.3e-14 53.9 0.2 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RVT_1 PF00078.22 EIE88219.1 - 1.4e-14 54.0 0.0 2.3e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EIE88219.1 - 8.6e-06 25.3 0.1 4.6e-05 23.0 0.0 2.4 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase zf-CCHC PF00098.18 EIE88219.1 - 6.3 6.9 22.0 0.023 14.6 3.2 3.6 3 0 0 3 3 3 0 Zinc knuckle zf-RVT PF13966.1 EIE88220.1 - 0.012 15.9 1.0 0.039 14.2 0.7 1.9 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase WD40 PF00400.27 EIE88221.1 - 4.2e-16 58.1 8.1 0.00044 20.0 0.1 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat Dynein_IC2 PF11540.3 EIE88221.1 - 0.0009 18.5 0.1 0.0022 17.3 0.1 1.6 1 0 0 1 1 1 1 Cytoplasmic dynein 1 intermediate chain 2 FlgN PF05130.7 EIE88221.1 - 1.4 9.1 10.0 2.7 8.2 1.3 2.3 2 0 0 2 2 2 0 FlgN protein DUF3835 PF12927.2 EIE88221.1 - 4.7 8.2 12.9 29 5.6 5.8 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3835) Flagellin_N PF00669.15 EIE88222.1 - 0.89 9.3 5.4 1.4 8.7 0.5 2.9 1 1 1 3 3 3 0 Bacterial flagellin N-terminal helical region GSIII_N PF12437.3 EIE88223.1 - 8.7e-68 226.8 0.1 1.4e-67 226.1 0.1 1.4 1 0 0 1 1 1 1 Glutamine synthetase type III N terminal Gln-synt_C PF00120.19 EIE88223.1 - 2.2e-37 128.6 0.0 4.2e-37 127.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Rep-A_N PF04057.7 EIE88224.1 - 5.1e-25 87.1 1.3 9.2e-25 86.3 0.9 1.4 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.20 EIE88224.1 - 3.8e-11 42.6 0.2 7.8e-09 35.2 0.0 3.0 3 0 0 3 3 3 2 OB-fold nucleic acid binding domain POT1 PF02765.12 EIE88224.1 - 0.05 13.5 0.0 0.15 11.9 0.0 1.7 2 0 0 2 2 2 0 Telomeric single stranded DNA binding POT1/CDC13 Cys_Met_Meta_PP PF01053.15 EIE88225.1 - 2.3e-141 470.5 0.0 2.6e-141 470.3 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EIE88225.1 - 2.1e-08 33.5 0.0 4.6e-08 32.4 0.0 1.4 2 0 0 2 2 2 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EIE88225.1 - 2.4e-08 33.4 0.0 5.9e-08 32.1 0.0 1.5 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 EIE88225.1 - 1.6e-06 27.1 0.1 2.5e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EIE88225.1 - 2.8e-06 26.7 0.0 4.5e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase SelA PF03841.8 EIE88225.1 - 9.6e-05 21.2 0.0 0.00021 20.1 0.0 1.5 1 1 0 1 1 1 1 L-seryl-tRNA selenium transferase Met_gamma_lyase PF06838.6 EIE88225.1 - 0.00058 18.2 0.1 0.001 17.4 0.0 1.5 1 1 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.11 EIE88225.1 - 0.0029 16.3 0.0 0.0039 15.9 0.0 1.1 1 0 0 1 1 1 1 Glycine cleavage system P-protein PWI PF01480.12 EIE88227.1 - 9.3e-29 99.3 0.5 3.1e-28 97.6 0.1 2.2 3 0 0 3 3 3 1 PWI domain BRAP2 PF07576.7 EIE88227.1 - 1.7e-22 79.0 0.9 5.2e-22 77.4 0.6 1.8 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.14 EIE88227.1 - 1.1e-16 60.7 9.2 1.3e-16 60.4 5.0 2.3 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 EIE88227.1 - 2.8e-05 23.8 9.6 2.8e-05 23.8 6.6 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EIE88227.1 - 0.0012 18.4 7.2 0.0012 18.4 5.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-DHHC PF01529.15 EIE88227.1 - 0.025 13.9 0.0 0.025 13.9 0.0 3.1 3 1 0 3 3 3 0 DHHC palmitoyltransferase zf-RING_5 PF14634.1 EIE88227.1 - 0.13 11.9 22.4 0.076 12.7 5.2 2.5 2 0 0 2 2 2 0 zinc-RING finger domain DUF1664 PF07889.7 EIE88227.1 - 0.46 10.2 6.4 1.1 9.1 4.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) zf-C3HC4_2 PF13923.1 EIE88227.1 - 1.8 8.6 24.5 0.021 14.8 6.3 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Adaptin_binding PF10199.4 EIE88228.1 - 0.47 10.7 6.3 0.93 9.7 4.4 1.5 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Aldo_ket_red PF00248.16 EIE88229.1 - 2.4e-46 157.8 0.4 7.1e-46 156.2 0.2 1.6 1 1 0 1 1 1 1 Aldo/keto reductase family Pribosyl_synth PF14572.1 EIE88230.1 - 2e-39 135.2 0.5 1.3e-32 113.0 0.1 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 EIE88230.1 - 3.9e-37 126.5 0.3 2.2e-34 117.6 0.0 2.6 3 0 0 3 3 3 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 EIE88230.1 - 9.8e-13 47.9 0.1 2e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EIE88230.1 - 0.0072 15.5 0.1 0.012 14.8 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.1 EIE88230.1 - 0.11 11.7 0.5 0.2 10.9 0.1 1.5 2 0 0 2 2 2 0 Phosphoribosyl transferase HLH PF00010.21 EIE88231.1 - 2.3e-19 68.7 3.2 5e-19 67.7 2.2 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF3106 PF11304.3 EIE88231.1 - 0.11 12.9 2.8 0.2 12.0 2.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3106) Cortex-I_coil PF09304.5 EIE88231.1 - 0.92 9.5 11.1 0.49 10.4 0.5 2.7 1 1 1 2 2 2 0 Cortexillin I, coiled coil SlyX PF04102.7 EIE88231.1 - 0.94 9.8 5.2 0.95 9.8 0.2 2.7 2 1 0 2 2 2 0 SlyX SAB PF04382.8 EIE88231.1 - 2.9 7.6 7.5 0.27 10.9 1.8 1.8 2 0 0 2 2 2 0 SAB domain TMPIT PF07851.8 EIE88231.1 - 3.4 6.6 8.3 0.49 9.4 3.3 1.3 2 0 0 2 2 2 0 TMPIT-like protein DUF1825 PF08855.5 EIE88231.1 - 6.3 6.8 8.3 9.9 6.2 0.6 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF1825) Macoilin PF09726.4 EIE88231.1 - 7.8 4.6 11.9 22 3.1 8.2 1.5 1 1 0 1 1 1 0 Transmembrane protein IncA PF04156.9 EIE88231.1 - 9 5.8 10.6 43 3.6 6.7 2.0 1 1 0 1 1 1 0 IncA protein NMD3 PF04981.8 EIE88232.1 - 2.3e-72 242.9 5.2 2.3e-72 242.9 3.6 1.8 2 0 0 2 2 2 1 NMD3 family RbsD_FucU PF05025.8 EIE88232.1 - 3.2 8.0 6.1 0.51 10.6 0.2 2.3 2 1 1 3 3 3 0 RbsD / FucU transport protein family Ribosomal_L24e PF01246.15 EIE88233.1 - 4.4e-30 103.3 4.7 9.6e-30 102.2 3.3 1.6 1 0 0 1 1 1 1 Ribosomal protein L24e Flu_M1 PF00598.14 EIE88233.1 - 0.095 12.1 0.1 0.13 11.6 0.1 1.2 1 0 0 1 1 1 0 Influenza Matrix protein (M1) IMS PF00817.15 EIE88234.1 - 2.9e-38 130.9 0.1 6.1e-37 126.6 0.0 2.6 3 0 0 3 3 3 1 impB/mucB/samB family IMS_C PF11799.3 EIE88234.1 - 2.8e-17 62.8 0.1 5.7e-17 61.8 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 EIE88234.1 - 1.9e-05 24.3 0.0 5e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 IMS family HHH motif SR-25 PF10500.4 EIE88234.1 - 0.00045 19.7 15.5 0.00045 19.7 10.8 1.8 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein APG17 PF04108.7 EIE88234.1 - 0.0028 16.5 1.6 0.0028 16.5 1.1 2.0 2 0 0 2 2 2 1 Autophagy protein Apg17 Trm112p PF03966.11 EIE88234.1 - 0.036 14.4 0.4 1.2 9.5 0.0 3.2 3 0 0 3 3 3 0 Trm112p-like protein DUF3246 PF11596.3 EIE88234.1 - 4.3 6.5 7.5 7.4 5.7 5.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) DUF4428 PF14471.1 EIE88235.1 - 0.042 13.6 0.6 0.15 11.8 0.4 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) TMF_DNA_bd PF12329.3 EIE88235.1 - 0.054 13.3 15.8 0.087 12.6 1.6 3.0 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding ALMT PF11744.3 EIE88235.1 - 0.11 11.0 2.6 0.14 10.7 1.8 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4164 PF13747.1 EIE88235.1 - 0.43 10.7 6.7 2.4 8.3 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) DUF724 PF05266.9 EIE88235.1 - 2.2 7.8 16.7 0.074 12.6 1.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF724) COG2 PF06148.6 EIE88235.1 - 4.3 7.2 13.1 0.2 11.5 2.5 2.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4220 PF13968.1 EIE88235.1 - 4.4 6.2 6.5 6.7 5.7 4.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) Tropomyosin_1 PF12718.2 EIE88235.1 - 5.3 6.8 21.5 43 3.9 14.9 2.4 1 1 0 1 1 1 0 Tropomyosin like MRP-L46 PF11788.3 EIE88236.1 - 2.7e-21 76.3 3.2 4.6e-21 75.5 2.2 1.3 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.23 EIE88236.1 - 0.00033 20.3 0.0 0.00087 18.9 0.0 1.7 2 0 0 2 2 2 1 NUDIX domain DUF4102 PF13356.1 EIE88236.1 - 0.081 12.8 0.0 0.22 11.4 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4102) RVT_1 PF00078.22 EIE88238.1 - 4.3e-36 124.2 0.0 8.5e-36 123.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.1 EIE88238.1 - 0.0019 18.4 1.1 0.0059 16.8 0.8 1.9 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase DDE_3 PF13358.1 EIE88239.1 - 4.3e-21 75.2 0.4 5.9e-21 74.7 0.3 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease RVT_1 PF00078.22 EIE88240.1 - 1.4e-13 50.7 0.1 2.7e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.12 EIE88240.1 - 5.1e-09 36.0 0.1 1.3e-08 34.8 0.1 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein UBN2 PF14223.1 EIE88240.1 - 0.082 12.6 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type rve PF00665.21 EIE88241.1 - 3.8e-23 81.8 0.0 6.7e-23 81.0 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 EIE88241.1 - 1.4e-07 31.0 0.1 2.6e-07 30.1 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 EIE88241.1 - 0.00031 20.0 1.6 0.00031 20.0 1.1 2.3 2 0 0 2 2 2 1 His(2)-Cys(2) zinc finger Tudor-knot PF11717.3 EIE88241.1 - 0.02 14.5 0.2 0.073 12.7 0.2 2.0 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain Rep_fac-A_C PF08646.5 EIE88242.1 - 0.073 12.7 0.1 0.17 11.5 0.1 1.6 1 0 0 1 1 1 0 Replication factor-A C terminal domain zf-DNA_Pol PF08996.5 EIE88242.1 - 0.079 12.3 0.3 0.16 11.3 0.2 1.5 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger zf-C2H2 PF00096.21 EIE88242.1 - 1.9 8.9 7.5 0.91 9.9 0.1 3.2 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIE88242.1 - 4.3 7.8 6.4 8.7 6.8 1.1 2.5 2 0 0 2 2 2 0 Zinc-finger double domain DDE_3 PF13358.1 EIE88243.1 - 1e-21 77.2 0.2 1.8e-21 76.4 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE88243.1 - 4.1e-16 58.7 2.0 9.9e-16 57.5 0.1 2.3 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 EIE88243.1 - 9.2e-08 32.2 0.2 3.6e-07 30.3 0.1 2.1 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EIE88243.1 - 4.7e-07 29.2 0.1 6.9e-05 22.3 0.0 2.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_7 PF02796.10 EIE88243.1 - 1.8e-06 27.6 3.4 5.7e-05 22.8 0.4 3.2 2 1 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_32 PF13565.1 EIE88243.1 - 4.8e-06 27.2 1.5 0.0002 22.0 0.0 3.7 3 1 1 4 4 4 1 Homeodomain-like domain HTH_33 PF13592.1 EIE88243.1 - 5.8e-06 25.7 0.2 2.3e-05 23.8 0.0 2.2 2 0 0 2 2 1 1 Winged helix-turn helix HTH_36 PF13730.1 EIE88243.1 - 0.00011 22.1 1.8 0.0086 16.1 0.4 3.4 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_28 PF13518.1 EIE88243.1 - 0.00022 21.1 0.0 0.13 12.2 0.0 3.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_21 PF13276.1 EIE88243.1 - 0.00026 20.9 0.3 0.0058 16.6 0.0 3.0 4 0 0 4 4 2 1 HTH-like domain HTH_24 PF13412.1 EIE88243.1 - 0.00064 19.0 0.3 0.18 11.2 0.1 2.9 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_Tnp_ISL3 PF13542.1 EIE88243.1 - 0.0009 18.3 0.1 0.14 11.3 0.0 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_11 PF08279.7 EIE88243.1 - 0.0014 18.2 0.7 0.13 11.9 0.1 2.5 2 0 0 2 2 2 1 HTH domain rve PF00665.21 EIE88243.1 - 0.0025 17.9 0.0 0.01 15.9 0.0 1.9 1 1 0 2 2 1 1 Integrase core domain HTH_38 PF13936.1 EIE88243.1 - 0.0046 16.4 0.2 0.021 14.3 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_17 PF12728.2 EIE88243.1 - 0.0096 16.1 0.2 3.8 7.8 0.0 4.1 4 0 0 4 4 4 1 Helix-turn-helix domain HTH_AsnC-type PF13404.1 EIE88243.1 - 0.015 14.8 0.1 0.06 12.9 0.0 2.0 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain LacI PF00356.16 EIE88243.1 - 0.015 14.9 0.4 2.7 7.6 0.1 2.5 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family HTH_3 PF01381.17 EIE88243.1 - 0.025 14.4 0.9 0.14 12.0 0.2 2.2 2 0 0 2 2 2 0 Helix-turn-helix Sigma54_DBD PF04552.8 EIE88243.1 - 0.027 13.9 0.2 0.4 10.1 0.1 2.6 2 0 0 2 2 2 0 Sigma-54, DNA binding domain DDE_Tnp_IS66 PF03050.9 EIE88243.1 - 0.031 13.4 0.7 4.7 6.3 0.1 3.0 2 1 0 2 2 2 0 Transposase IS66 family HTH_22 PF13309.1 EIE88243.1 - 0.035 13.8 0.2 0.21 11.3 0.1 2.2 2 0 0 2 2 2 0 HTH domain GerE PF00196.14 EIE88243.1 - 0.038 13.3 0.9 0.084 12.2 0.1 2.0 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family Trp_repressor PF01371.14 EIE88243.1 - 0.04 13.8 0.2 0.13 12.2 0.1 1.8 1 0 0 1 1 1 0 Trp repressor protein HMG_box_2 PF09011.5 EIE88243.1 - 0.055 13.8 1.9 0.084 13.2 0.2 2.1 2 0 0 2 2 2 0 HMG-box domain DUF3107 PF11305.3 EIE88243.1 - 0.068 13.0 0.1 17 5.3 0.0 2.7 2 1 1 3 3 2 0 Protein of unknown function (DUF3107) KorB PF08535.5 EIE88243.1 - 0.089 12.9 0.1 0.26 11.4 0.0 1.8 1 0 0 1 1 1 0 KorB domain HMG_box PF00505.14 EIE88243.1 - 0.098 12.9 1.4 0.5 10.6 0.6 2.5 2 0 0 2 2 2 0 HMG (high mobility group) box Acetyltransf_2 PF00797.12 EIE88243.1 - 0.11 12.0 0.8 3.2 7.2 0.0 2.5 2 1 0 2 2 2 0 N-acetyltransferase GntR PF00392.16 EIE88243.1 - 0.11 11.9 0.1 6 6.3 0.0 2.5 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family TrmB PF01978.14 EIE88243.1 - 0.15 11.7 0.6 1.2 8.9 0.2 2.4 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB THP2 PF09432.5 EIE88243.1 - 0.52 10.1 3.5 1.1 9.1 0.1 3.0 4 0 0 4 4 4 0 Tho complex subunit THP2 DUF4633 PF15464.1 EIE88244.1 - 0.017 14.9 1.9 0.02 14.7 1.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4633) RVT_1 PF00078.22 EIE88245.1 - 1.3e-16 60.5 0.0 1.7e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SIS PF01380.17 EIE88246.1 - 0.03 13.9 0.1 0.038 13.5 0.1 1.2 1 0 0 1 1 1 0 SIS domain RVT_1 PF00078.22 EIE88247.1 - 2.3e-14 53.2 0.9 6.5e-14 51.8 0.6 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 EIE88247.1 - 0.00013 22.4 0.1 0.0003 21.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 EIE88247.1 - 0.00031 20.6 0.1 0.0013 18.5 0.0 2.2 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EIE88247.1 - 0.049 13.4 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease rve PF00665.21 EIE88248.1 - 1.6e-18 66.9 0.0 3.1e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 EIE88248.1 - 4.9e-07 29.3 1.1 9.3e-07 28.4 0.8 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 EIE88248.1 - 0.0043 16.7 0.6 0.0089 15.7 0.4 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain YcgR_2 PF12945.2 EIE88248.1 - 0.01 15.6 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 Flagellar protein YcgR DDE_Tnp_IS1595 PF12762.2 EIE88249.1 - 5.9e-23 81.3 0.8 1e-22 80.5 0.3 1.6 2 0 0 2 2 2 1 ISXO2-like transposase domain Exo_endo_phos_2 PF14529.1 EIE88250.1 - 7.4e-19 67.5 0.0 1.7e-18 66.3 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EIE88250.1 - 1.3e-06 28.5 0.3 3.7e-06 27.0 0.0 1.9 2 1 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Mod_r PF07200.8 EIE88251.1 - 0.026 14.4 0.1 0.046 13.6 0.1 1.3 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Matrilin_ccoil PF10393.4 EIE88251.1 - 0.056 12.8 0.3 0.12 11.7 0.2 1.5 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin Reo_sigmaC PF04582.7 EIE88251.1 - 0.076 12.1 0.3 0.11 11.6 0.2 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF1395 PF07160.7 EIE88251.1 - 0.11 11.9 0.1 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1395) DUF904 PF06005.7 EIE88251.1 - 0.15 12.4 2.4 0.33 11.2 1.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF904) DivIC PF04977.10 EIE88251.1 - 0.18 11.2 0.8 0.38 10.2 0.5 1.5 1 0 0 1 1 1 0 Septum formation initiator DUF4164 PF13747.1 EIE88251.1 - 2.4 8.3 8.2 0.72 10.0 1.8 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) HTH_Tnp_4 PF13613.1 EIE88252.1 - 0.00014 21.3 0.0 0.00029 20.3 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease HTH_23 PF13384.1 EIE88252.1 - 0.00063 19.3 0.1 0.0021 17.6 0.0 1.9 2 1 0 2 2 2 1 Homeodomain-like domain HTH_36 PF13730.1 EIE88252.1 - 0.016 15.3 0.2 0.73 10.0 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_28 PF13518.1 EIE88252.1 - 0.072 13.1 0.0 0.67 10.0 0.0 2.3 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_30 PF13556.1 EIE88252.1 - 0.085 12.4 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain RecX PF02631.11 EIE88252.1 - 0.092 12.9 0.1 0.14 12.4 0.1 1.3 1 0 0 1 1 1 0 RecX family RVT_1 PF00078.22 EIE88253.1 - 3.3e-28 98.5 0.0 5.4e-28 97.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EIE88253.1 - 1.5e-18 66.5 0.0 3.4e-18 65.3 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EIE88253.1 - 5.4e-05 23.2 0.0 0.00018 21.5 0.0 1.9 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LacI PF00356.16 EIE88254.1 - 0.27 10.8 2.7 0.92 9.1 0.0 2.7 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family Exo_endo_phos_2 PF14529.1 EIE88255.1 - 5.4e-14 51.8 0.0 6e-14 51.6 0.0 1.0 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EIE88255.1 - 0.015 15.2 0.1 0.019 14.9 0.1 1.1 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family TPR_MLP1_2 PF07926.7 EIE88256.1 - 0.00012 21.8 0.1 0.00017 21.3 0.1 1.2 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein Paramyx_P_V_C PF03210.8 EIE88256.1 - 0.0044 16.9 0.1 0.008 16.0 0.1 1.5 1 0 0 1 1 1 1 Paramyxovirus P/V phosphoprotein C-terminal DUF972 PF06156.8 EIE88256.1 - 0.049 13.9 0.3 0.08 13.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Phage_GP20 PF06810.6 EIE88256.1 - 0.073 12.5 0.1 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 Reo_sigmaC PF04582.7 EIE88256.1 - 0.075 12.2 3.5 0.11 11.7 2.4 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DivIC PF04977.10 EIE88256.1 - 0.12 11.9 0.2 0.21 11.0 0.1 1.4 1 0 0 1 1 1 0 Septum formation initiator DUF4200 PF13863.1 EIE88256.1 - 0.16 11.9 0.1 0.25 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) bZIP_2 PF07716.10 EIE88256.1 - 0.2 11.4 2.7 1.6 8.6 0.1 2.4 1 1 1 2 2 2 0 Basic region leucine zipper RHIM PF12721.2 EIE88256.1 - 2.5 8.5 7.4 0.31 11.4 1.5 2.2 2 0 0 2 2 2 0 RIP homotypic interaction motif Transposase_21 PF02992.9 EIE88257.1 - 2e-21 76.1 0.2 4.3e-21 75.0 0.0 1.6 2 0 0 2 2 2 1 Transposase family tnp2 DUF1258 PF06869.7 EIE88257.1 - 0.0052 15.9 0.0 0.0096 15.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) 3HCDH_N PF02737.13 EIE88257.1 - 0.016 14.8 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Rep_fac_C PF08542.6 EIE88257.1 - 0.12 12.3 0.1 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 Replication factor C C-terminal domain Epsilon_antitox PF08998.6 EIE88257.1 - 0.49 10.4 4.5 0.34 10.9 0.2 2.4 2 0 0 2 2 2 0 Bacterial epsilon antitoxin Asp_protease PF09668.5 EIE88259.1 - 2.6e-10 39.9 0.0 6e-10 38.7 0.0 1.6 2 0 0 2 2 2 1 Aspartyl protease Asp_protease_2 PF13650.1 EIE88259.1 - 8.5e-09 35.8 0.0 1.5e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 EIE88259.1 - 2.8e-07 30.3 0.0 8e-07 28.9 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.6 EIE88259.1 - 9.6e-07 28.8 0.0 1.9e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EIE88259.1 - 1.2e-05 25.0 0.1 2.1e-05 24.2 0.1 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1043 PF06295.7 EIE88259.1 - 0.088 12.4 3.8 0.2 11.3 2.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF1759 PF03564.10 EIE88260.1 - 0.0024 17.6 0.2 0.0076 16.0 0.2 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) rve PF00665.21 EIE88262.1 - 7.1e-18 64.8 0.0 3.2e-17 62.7 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 EIE88262.1 - 3.4e-14 52.7 0.9 9e-14 51.3 0.6 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 EIE88262.1 - 3.8e-05 24.0 0.1 0.0004 20.8 0.0 2.4 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.15 EIE88262.1 - 0.00048 19.9 0.1 0.0018 18.1 0.0 2.0 1 0 0 1 1 1 1 Retroviral aspartyl protease YcgR_2 PF12945.2 EIE88262.1 - 0.047 13.5 0.0 0.76 9.6 0.0 2.5 2 0 0 2 2 2 0 Flagellar protein YcgR gag-asp_proteas PF13975.1 EIE88262.1 - 0.061 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DDE_Tnp_IS1595 PF12762.2 EIE88263.1 - 5.9e-23 81.3 0.8 1e-22 80.5 0.3 1.6 2 0 0 2 2 2 1 ISXO2-like transposase domain LexA_DNA_bind PF01726.11 EIE88264.1 - 0.11 12.1 0.1 0.2 11.2 0.0 1.5 1 1 0 1 1 1 0 LexA DNA binding domain RRF_GI PF12614.3 EIE88266.1 - 0.022 14.5 0.1 0.023 14.5 0.1 1.2 1 0 0 1 1 1 0 Ribosome recycling factor HTH_Tnp_Tc3_2 PF01498.13 EIE88267.1 - 2.3e-08 33.9 0.2 3.5e-08 33.3 0.2 1.3 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.1 EIE88267.1 - 0.019 14.7 0.0 0.04 13.6 0.0 1.5 1 0 0 1 1 1 0 DDE superfamily endonuclease DDE_Tnp_ISAZ013 PF07592.6 EIE88267.1 - 0.12 11.1 0.0 0.15 10.8 0.0 1.1 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain rve PF00665.21 EIE88268.1 - 1.9e-22 79.6 0.0 4.5e-22 78.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE88268.1 - 2.6e-13 49.8 0.1 5.2e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.12 EIE88268.1 - 8.2e-09 35.4 0.1 2.3e-08 34.0 0.1 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein Chromo PF00385.19 EIE88268.1 - 4.2e-08 32.7 0.1 9.7e-08 31.5 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 EIE88268.1 - 0.00047 19.4 1.6 0.0015 17.9 1.1 1.9 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger UBN2 PF14223.1 EIE88268.1 - 0.13 12.0 0.0 0.36 10.6 0.0 1.8 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type RVT_1 PF00078.22 EIE88270.1 - 1.8e-16 60.1 0.0 2.6e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) UAA PF08449.6 EIE88272.1 - 2.1e-78 263.3 18.0 3.5e-78 262.5 12.5 1.3 1 0 0 1 1 1 1 UAA transporter family Pox_A14 PF05767.7 EIE88272.1 - 0.0005 19.9 0.4 0.0019 18.1 0.3 2.0 1 0 0 1 1 1 1 Poxvirus virion envelope protein A14 TPT PF03151.11 EIE88272.1 - 0.044 13.4 30.4 0.052 13.1 6.3 3.6 2 2 0 3 3 3 0 Triose-phosphate Transporter family EamA PF00892.15 EIE88272.1 - 1.1 9.2 30.7 0.11 12.5 7.7 3.2 3 0 0 3 3 3 0 EamA-like transporter family UPF0546 PF10639.4 EIE88272.1 - 2.6 7.8 11.8 3.3 7.5 2.3 2.6 2 0 0 2 2 2 0 Uncharacterised protein family UPF0546 Vezatin PF12632.2 EIE88273.1 - 2.5e-24 85.7 6.8 4.6e-24 84.8 4.7 1.5 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes DDE_3 PF13358.1 EIE88274.1 - 4.9e-29 100.9 0.0 1e-28 99.9 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 EIE88274.1 - 4.2e-10 39.7 0.1 1.7e-09 37.8 0.0 1.9 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.1 EIE88274.1 - 4e-08 33.9 0.3 1.1e-07 32.5 0.0 2.0 2 0 0 2 2 1 1 Homeodomain-like domain HTH_23 PF13384.1 EIE88274.1 - 2.6e-07 30.0 1.8 4.3e-05 23.0 0.0 2.9 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.1 EIE88274.1 - 3.4e-07 30.1 2.9 1.7e-05 24.7 0.1 3.1 3 0 0 3 3 3 1 Helix-turn-helix domain rve PF00665.21 EIE88274.1 - 0.00035 20.6 0.0 0.0052 16.8 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain HTH_17 PF12728.2 EIE88274.1 - 0.0012 19.1 0.3 1.7 8.9 0.2 2.7 2 0 0 2 2 2 2 Helix-turn-helix domain DDE_1 PF03184.14 EIE88274.1 - 0.0015 17.7 0.0 0.031 13.4 0.0 2.4 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_1 PF01527.15 EIE88274.1 - 0.0051 16.7 1.1 0.014 15.3 0.1 2.0 2 0 0 2 2 2 1 Transposase HTH_Tnp_Tc3_2 PF01498.13 EIE88274.1 - 0.028 14.4 0.0 0.14 12.2 0.0 2.2 2 0 0 2 2 2 0 Transposase HTH_30 PF13556.1 EIE88274.1 - 0.075 12.6 0.6 0.2 11.2 0.1 1.9 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain HTH_Tnp_ISL3 PF13542.1 EIE88274.1 - 0.076 12.2 0.0 0.16 11.1 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 DDE_3 PF13358.1 EIE88275.1 - 4.9e-29 100.9 0.0 1e-28 99.9 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 EIE88275.1 - 4.2e-10 39.7 0.1 1.7e-09 37.8 0.0 1.9 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.1 EIE88275.1 - 4e-08 33.9 0.3 1.1e-07 32.5 0.0 2.0 2 0 0 2 2 1 1 Homeodomain-like domain HTH_23 PF13384.1 EIE88275.1 - 2.6e-07 30.0 1.8 4.3e-05 23.0 0.0 2.9 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.1 EIE88275.1 - 3.4e-07 30.1 2.9 1.7e-05 24.7 0.1 3.1 3 0 0 3 3 3 1 Helix-turn-helix domain rve PF00665.21 EIE88275.1 - 0.00035 20.6 0.0 0.0052 16.8 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain HTH_17 PF12728.2 EIE88275.1 - 0.0012 19.1 0.3 1.7 8.9 0.2 2.7 2 0 0 2 2 2 2 Helix-turn-helix domain DDE_1 PF03184.14 EIE88275.1 - 0.0015 17.7 0.0 0.031 13.4 0.0 2.4 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_1 PF01527.15 EIE88275.1 - 0.0051 16.7 1.1 0.014 15.3 0.1 2.0 2 0 0 2 2 2 1 Transposase HTH_Tnp_Tc3_2 PF01498.13 EIE88275.1 - 0.028 14.4 0.0 0.14 12.2 0.0 2.2 2 0 0 2 2 2 0 Transposase HTH_30 PF13556.1 EIE88275.1 - 0.075 12.6 0.6 0.2 11.2 0.1 1.9 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain HTH_Tnp_ISL3 PF13542.1 EIE88275.1 - 0.076 12.2 0.0 0.16 11.1 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Glycos_transf_2 PF00535.21 EIE88277.1 - 0.00036 20.2 0.1 0.00072 19.2 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Cag12 PF13117.1 EIE88277.1 - 6.9 6.6 8.0 1.6 8.6 0.0 3.1 4 1 0 4 4 4 0 Cag pathogenicity island protein Cag12 Grp1_Fun34_YaaH PF01184.14 EIE88278.1 - 2.5e-69 232.7 16.5 3.3e-69 232.4 11.4 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family TPR_11 PF13414.1 EIE88279.1 - 7.2e-07 28.7 16.0 0.0015 18.1 0.2 5.5 6 1 1 7 7 7 2 TPR repeat TPR_17 PF13431.1 EIE88279.1 - 0.00081 19.4 0.3 6.9 7.1 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 EIE88279.1 - 0.0011 19.5 9.8 3.3 8.5 0.1 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TOM20_plant PF06552.7 EIE88279.1 - 0.0028 17.2 2.9 0.005 16.4 1.1 2.2 2 1 0 2 2 2 1 Plant specific mitochondrial import receptor subunit TOM20 AAA_25 PF13481.1 EIE88279.1 - 0.1 11.9 0.3 0.22 10.9 0.2 1.4 1 0 0 1 1 1 0 AAA domain TPR_1 PF00515.23 EIE88279.1 - 2.5 7.8 7.2 32 4.3 0.2 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat Sel1 PF08238.7 EIE88279.1 - 5 7.9 9.7 11 6.8 0.5 3.8 4 0 0 4 4 4 0 Sel1 repeat SH3_2 PF07653.12 EIE88280.1 - 0.0012 18.3 0.0 0.0024 17.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain FCH PF00611.18 EIE88280.1 - 0.0029 17.7 4.1 0.0057 16.8 0.0 3.3 2 1 1 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain PLA2_B PF01735.13 EIE88281.1 - 1.3e-40 138.9 0.1 2.6e-20 72.0 0.1 2.1 2 0 0 2 2 2 2 Lysophospholipase catalytic domain UPF0270 PF06794.7 EIE88281.1 - 0.077 12.7 0.1 0.35 10.6 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0270) GTP_CH_N PF12471.3 EIE88282.1 - 8.4e-92 306.1 0.0 1.2e-91 305.6 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.15 EIE88282.1 - 6.1e-17 61.3 0.0 9.7e-17 60.7 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II UPRTase PF14681.1 EIE88283.1 - 1.4e-63 213.8 0.0 1.6e-63 213.6 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EIE88283.1 - 0.001 18.7 0.0 0.0015 18.2 0.0 1.5 1 1 0 1 1 1 1 Phosphoribosyl transferase domain MRP-L20 PF12824.2 EIE88284.1 - 7.9e-23 81.2 0.9 9.7e-23 80.9 0.6 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Ku PF02735.11 EIE88285.1 - 5.3e-22 78.2 1.3 7.3e-22 77.7 0.1 1.8 2 0 0 2 2 2 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.6 EIE88285.1 - 7.7e-12 45.1 2.7 8.9e-11 41.7 0.7 2.9 2 1 1 3 3 3 2 Ku C terminal domain like S-antigen PF05756.6 EIE88286.1 - 0.12 12.3 2.0 1.8 8.5 2.0 2.2 2 0 0 2 2 2 0 S-antigen protein DDE_3 PF13358.1 EIE88289.1 - 7.3e-20 71.2 0.1 1.3e-19 70.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE88289.1 - 2.2e-08 34.0 2.9 3.1e-08 33.5 0.3 2.4 1 1 1 2 2 2 1 Transposase rve PF00665.21 EIE88289.1 - 0.036 14.1 0.1 0.093 12.8 0.0 1.8 2 0 0 2 2 2 0 Integrase core domain HTH_12 PF08461.5 EIE88289.1 - 0.11 12.2 0.1 0.34 10.6 0.0 1.8 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain HTH_29 PF13551.1 EIE88289.1 - 0.23 11.6 2.9 0.23 11.6 0.8 2.0 2 1 0 2 2 2 0 Winged helix-turn helix DUF1033 PF06279.6 EIE88289.1 - 0.33 10.7 4.6 0.38 10.5 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1033) NFRKB_winged PF14465.1 EIE88289.1 - 0.54 10.1 3.7 5.8 6.8 0.4 2.9 2 1 1 3 3 3 0 NFRKB Winged Helix-like HTH_32 PF13565.1 EIE88289.1 - 0.71 10.7 5.9 0.27 12.0 0.6 2.7 4 0 0 4 4 4 0 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.1 EIE88289.1 - 1.8 7.8 3.8 1.1 8.5 0.1 2.4 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 Exo_endo_phos PF03372.18 EIE88290.1 - 2.8e-14 53.6 4.6 5.8e-14 52.6 3.2 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EIE88290.1 - 6.6e-11 41.8 1.8 1.7e-10 40.5 1.2 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase zf-CCHC PF00098.18 EIE88290.1 - 0.0018 18.1 1.9 0.0036 17.1 1.3 1.5 1 0 0 1 1 1 1 Zinc knuckle HTH_IclR PF09339.5 EIE88291.1 - 0.0002 20.8 0.3 0.03 13.9 0.0 2.2 2 0 0 2 2 2 2 IclR helix-turn-helix domain RNA_pol_Rpb1_3 PF04983.13 EIE88291.1 - 0.063 13.0 0.0 0.069 12.8 0.0 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 3 Mak10 PF04112.8 EIE88291.1 - 0.086 12.0 0.1 0.1 11.7 0.1 1.1 1 0 0 1 1 1 0 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase RCC1_2 PF13540.1 EIE88292.1 - 2.4e-05 23.7 6.8 0.0051 16.3 1.8 2.9 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 EIE88292.1 - 0.029 14.5 0.0 13 6.0 0.0 3.1 3 0 0 3 3 3 0 Regulator of chromosome condensation (RCC1) repeat ADH_N PF08240.7 EIE88293.1 - 1e-26 92.8 7.8 1.8e-26 92.0 5.4 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIE88293.1 - 4.7e-19 68.2 0.0 6.7e-19 67.7 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 EIE88293.1 - 7.2e-05 22.4 0.1 0.00013 21.5 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 EIE88293.1 - 7.9e-05 21.8 0.0 0.00026 20.1 0.0 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 EIE88293.1 - 0.0047 16.7 0.0 0.0076 16.1 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 EIE88293.1 - 0.05 13.2 0.0 0.071 12.7 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.16 EIE88293.1 - 0.099 12.1 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ThiF PF00899.16 EIE88293.1 - 0.11 12.3 0.1 0.45 10.3 0.1 2.0 2 0 0 2 2 2 0 ThiF family Methyltransf_31 PF13847.1 EIE88293.1 - 0.11 12.0 0.0 0.84 9.2 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Kelch_4 PF13418.1 EIE88295.1 - 1.7e-15 56.5 2.8 1.6e-05 24.5 0.0 4.9 4 1 0 4 4 4 3 Galactose oxidase, central domain Kelch_5 PF13854.1 EIE88295.1 - 5.9e-15 54.8 0.0 3.7e-05 23.5 0.0 3.6 3 0 0 3 3 3 3 Kelch motif Kelch_6 PF13964.1 EIE88295.1 - 5.3e-14 51.7 1.9 0.0012 18.9 0.0 4.5 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.1 EIE88295.1 - 8.2e-13 48.1 3.4 8.3e-07 29.0 0.1 5.3 5 0 0 5 5 5 2 Galactose oxidase, central domain BTB PF00651.26 EIE88295.1 - 8.3e-09 35.4 0.0 1.5e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Kelch_1 PF01344.20 EIE88295.1 - 2.4e-08 33.3 0.1 0.063 12.8 0.0 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.10 EIE88295.1 - 0.00022 20.8 0.2 0.6 9.9 0.0 4.1 4 0 0 4 4 4 1 Kelch motif Lip_prot_lig_C PF10437.4 EIE88296.1 - 2.6e-13 49.4 0.0 1.1e-12 47.4 0.0 2.1 2 0 0 2 2 2 1 Bacterial lipoate protein ligase C-terminus BPL_LplA_LipB PF03099.14 EIE88296.1 - 3.4e-10 39.9 0.0 5.5e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family ADK PF00406.17 EIE88297.1 - 2.9e-48 163.5 0.1 3.7e-48 163.2 0.1 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 EIE88297.1 - 8.2e-12 45.5 1.0 1e-11 45.2 0.1 1.5 2 0 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.12 EIE88297.1 - 2.1e-09 37.0 1.5 3e-05 23.4 0.2 2.1 2 0 0 2 2 2 2 Thymidylate kinase AAA_17 PF13207.1 EIE88297.1 - 2.1e-08 35.0 0.1 2.8e-08 34.5 0.1 1.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EIE88297.1 - 1.1e-07 31.8 0.0 2.6e-07 30.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EIE88297.1 - 0.00015 20.9 0.0 0.0002 20.5 0.0 1.3 1 1 0 1 1 1 1 Zeta toxin NTase_sub_bind PF08780.6 EIE88297.1 - 0.048 13.4 0.7 1.2 8.8 0.0 2.2 1 1 1 2 2 2 0 Nucleotidyltransferase substrate binding protein like SRP54 PF00448.17 EIE88297.1 - 0.083 12.3 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ScpA_ScpB PF02616.9 EIE88297.1 - 0.25 10.9 3.7 0.33 10.5 1.9 1.6 1 1 1 2 2 2 0 ScpA/B protein RhoGAP PF00620.22 EIE88298.1 - 1.2e-28 99.5 0.2 2.4e-28 98.6 0.1 1.5 1 0 0 1 1 1 1 RhoGAP domain DUF1708 PF08101.6 EIE88298.1 - 0.0098 14.7 0.0 0.016 14.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) Vps5 PF09325.5 EIE88301.1 - 4.7e-08 32.5 8.4 5.2e-08 32.4 5.5 1.3 1 1 0 1 1 1 1 Vps5 C terminal like CENP-F_leu_zip PF10473.4 EIE88301.1 - 0.0051 16.6 10.1 0.011 15.5 7.0 1.6 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Pox_J1 PF03338.10 EIE88301.1 - 0.074 12.7 1.8 0.78 9.4 0.0 2.3 1 1 0 2 2 2 0 Poxvirus J1 protein GIDA PF01134.17 EIE88301.1 - 0.12 11.1 0.2 0.17 10.7 0.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A TMF_TATA_bd PF12325.3 EIE88301.1 - 0.18 11.5 10.6 0.43 10.3 2.5 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Indigoidine_A PF04227.7 EIE88302.1 - 2.5e-45 154.9 1.0 3.3e-26 92.1 0.3 2.0 1 1 1 2 2 2 2 Indigoidine synthase A like protein TPP_enzyme_N PF02776.13 EIE88302.1 - 0.013 15.0 0.1 0.021 14.2 0.1 1.4 1 1 0 1 1 1 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Scramblase PF03803.10 EIE88303.1 - 2.6e-52 177.1 0.1 3.3e-52 176.7 0.0 1.1 1 0 0 1 1 1 1 Scramblase Caa3_CtaG PF09678.5 EIE88306.1 - 0.14 11.0 2.3 0.15 10.9 1.6 1.1 1 0 0 1 1 1 0 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) Lectin_legB PF00139.14 EIE88308.1 - 2.6e-18 66.2 0.0 3.7e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 Legume lectin domain Lectin_leg-like PF03388.8 EIE88308.1 - 1.8e-05 24.0 0.0 0.0016 17.6 0.0 2.2 2 0 0 2 2 2 2 Legume-like lectin family Rad4 PF03835.10 EIE88308.1 - 9.3e-05 21.8 0.2 0.0002 20.7 0.1 1.5 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Sulfotransfer_3 PF13469.1 EIE88309.1 - 0.048 14.5 0.0 0.059 14.3 0.0 1.3 1 0 0 1 1 1 0 Sulfotransferase family DivIC PF04977.10 EIE88311.1 - 0.0022 17.4 2.0 0.0057 16.1 1.4 1.6 1 0 0 1 1 1 1 Septum formation initiator Lebercilin PF15619.1 EIE88311.1 - 0.012 15.0 2.6 0.012 15.0 1.8 1.5 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Herpes_BLRF2 PF05812.7 EIE88311.1 - 0.016 15.0 0.1 0.032 14.0 0.1 1.5 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein SlyX PF04102.7 EIE88311.1 - 0.07 13.5 0.8 0.15 12.4 0.5 1.6 1 0 0 1 1 1 0 SlyX Gag_spuma PF03276.9 EIE88311.1 - 0.11 10.7 7.0 0.15 10.3 4.8 1.1 1 0 0 1 1 1 0 Spumavirus gag protein Cep57_CLD_2 PF14197.1 EIE88311.1 - 0.4 10.6 2.5 1 9.3 1.7 1.6 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 TFIIF_alpha PF05793.7 EIE88311.1 - 9.5 4.4 5.8 12 4.0 4.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) zf-CCHC PF00098.18 EIE88313.1 - 2.7e-05 23.8 14.4 0.0022 17.8 1.3 2.2 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 EIE88313.1 - 0.021 14.5 13.0 0.052 13.2 1.1 2.8 3 0 0 3 3 3 0 Zinc knuckle TMEM51 PF15345.1 EIE88313.1 - 0.37 10.4 3.6 0.47 10.1 2.5 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 zf-CCHC_3 PF13917.1 EIE88313.1 - 0.47 10.2 14.8 0.18 11.5 1.9 2.3 1 1 1 2 2 2 0 Zinc knuckle Cytomega_UL20A PF05984.7 EIE88313.1 - 3.2 8.0 8.2 2.6 8.3 4.1 1.8 1 1 1 2 2 2 0 Cytomegalovirus UL20A protein RVT_1 PF00078.22 EIE88314.1 - 6.5e-21 74.6 0.1 1.3e-20 73.6 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Dam PF05869.6 EIE88314.1 - 6.6e-07 28.9 0.3 2e-06 27.3 0.2 1.8 1 0 0 1 1 1 1 DNA N-6-adenine-methyltransferase (Dam) RVT_3 PF13456.1 EIE88314.1 - 0.0019 17.9 0.0 0.0054 16.4 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase-like Phage_int_SAM_4 PF13495.1 EIE88314.1 - 0.014 15.7 1.8 0.027 14.7 0.3 2.3 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_1 PF02899.12 EIE88314.1 - 0.026 14.6 3.4 0.042 14.0 0.6 2.6 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain DUF1204 PF06721.6 EIE88314.1 - 0.17 11.1 0.0 0.32 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1204) Ipi1_N PF12333.3 EIE88314.1 - 0.78 9.7 7.2 7.1 6.6 0.2 3.2 3 0 0 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation DDE_3 PF13358.1 EIE88315.1 - 2.4e-23 82.4 0.0 1.1e-22 80.3 0.0 2.0 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 EIE88315.1 - 0.00016 21.7 0.0 0.00029 20.9 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EIE88315.1 - 0.0053 16.3 0.0 0.012 15.2 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.1 EIE88315.1 - 0.053 13.5 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain DUF1804 PF08822.6 EIE88315.1 - 0.066 12.9 1.0 0.17 11.6 0.3 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1804) AIP3 PF03915.8 EIE88318.1 - 0.014 14.2 5.5 0.017 14.0 3.8 1.0 1 0 0 1 1 1 0 Actin interacting protein 3 DUF484 PF04340.7 EIE88318.1 - 0.25 10.7 4.7 0.36 10.2 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF484 DUF948 PF06103.6 EIE88318.1 - 0.32 10.8 3.3 0.62 9.9 2.3 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) SlyX PF04102.7 EIE88318.1 - 1 9.7 12.7 0.36 11.2 2.6 2.3 2 0 0 2 2 2 0 SlyX Mto2_bdg PF12808.2 EIE88318.1 - 1.2 9.2 13.1 0.16 12.1 2.2 2.4 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DivIVA PF05103.8 EIE88318.1 - 2.4 8.2 7.6 3.6 7.6 5.3 1.3 1 0 0 1 1 1 0 DivIVA protein Spc24 PF08286.6 EIE88318.1 - 5.2 6.8 10.5 0.63 9.7 3.4 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF3450 PF11932.3 EIE88318.1 - 8.1 5.6 18.7 58 2.8 13.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) NTP_transferase PF00483.18 EIE88320.1 - 1.1e-32 113.2 0.0 1.6e-32 112.7 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 EIE88320.1 - 6.7e-13 47.5 10.6 6e-10 38.1 1.1 3.4 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EIE88320.1 - 1.2e-06 27.9 10.5 1.1e-05 24.9 2.5 3.3 3 1 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase NTP_transf_3 PF12804.2 EIE88320.1 - 0.017 15.2 0.0 0.025 14.6 0.0 1.3 1 0 0 1 1 1 0 MobA-like NTP transferase domain DUF2810 PF10928.3 EIE88320.1 - 0.045 13.4 0.1 0.11 12.2 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2810) SNF2_N PF00176.18 EIE88321.1 - 9.1e-58 195.4 0.7 2.1e-57 194.2 0.5 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EIE88321.1 - 5.1e-16 58.3 0.1 3e-15 55.8 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SnAC PF14619.1 EIE88321.1 - 1.8e-05 24.8 0.3 6.9e-05 22.9 0.2 2.1 1 0 0 1 1 1 1 Snf2-ATP coupling, chromatin remodelling complex AAA_22 PF13401.1 EIE88321.1 - 0.00036 20.6 0.3 0.069 13.2 0.0 3.2 2 1 0 2 2 2 1 AAA domain DUF1087 PF06465.8 EIE88321.1 - 0.00071 19.4 0.6 0.003 17.4 0.4 2.1 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1087) Chitin_synth_2 PF03142.10 EIE88322.1 - 1.6e-147 492.1 0.2 2.5e-147 491.4 0.1 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 EIE88322.1 - 1.6e-126 423.1 9.8 4.5e-126 421.6 6.8 1.7 1 1 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.23 EIE88322.1 - 2e-18 65.9 3.3 4.4e-09 36.0 0.0 3.0 3 0 0 3 3 3 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.1 EIE88322.1 - 4.1e-08 33.1 0.0 4.1e-08 33.1 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EIE88322.1 - 1.7e-07 31.2 0.0 9.6e-05 22.2 0.0 2.7 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EIE88322.1 - 5.1e-06 26.2 0.0 0.00019 21.1 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EIE88322.1 - 0.00097 18.4 0.0 0.002 17.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 AAA_22 PF13401.1 EIE88322.1 - 0.017 15.2 0.1 0.052 13.6 0.1 1.8 1 0 0 1 1 1 0 AAA domain Jiv90 PF14901.1 EIE88322.1 - 0.025 14.5 3.6 3.9 7.5 0.1 3.6 4 0 0 4 4 4 0 Cleavage inducing molecular chaperone T2SE PF00437.15 EIE88322.1 - 0.067 12.0 0.2 0.16 10.8 0.1 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Linker_histone PF00538.14 EIE88326.1 - 2.1e-14 53.3 0.2 2.1e-14 53.3 0.1 2.3 2 1 0 2 2 2 1 linker histone H1 and H5 family MIP-T3 PF10243.4 EIE88326.1 - 3.5 6.0 77.8 5.2 5.4 53.9 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Dapper PF15268.1 EIE88326.1 - 6.8 5.3 40.8 7.3 5.2 28.3 1.2 1 0 0 1 1 1 0 Dapper RibD_C PF01872.12 EIE88327.1 - 4.2e-23 82.0 0.0 1.1e-22 80.6 0.0 1.6 1 1 0 1 1 1 1 RibD C-terminal domain Sec7 PF01369.15 EIE88328.1 - 4.9e-57 192.6 0.0 2.6e-56 190.3 0.0 2.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 EIE88328.1 - 1.6e-46 157.7 3.3 2.5e-46 157.2 0.9 2.5 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EIE88328.1 - 3e-29 100.3 8.4 1.2e-27 95.2 0.1 6.1 6 0 0 6 6 6 1 Domain of unknown function (DUF1981) CENP-O PF09496.5 EIE88328.1 - 0.0024 18.0 0.0 0.0076 16.4 0.0 1.9 1 0 0 1 1 1 1 Cenp-O kinetochore centromere component IBR PF01485.16 EIE88329.1 - 1.4e-19 69.7 36.5 9.1e-11 41.4 4.0 3.3 3 0 0 3 3 3 2 IBR domain RNA_pol_Rpb4 PF03874.11 EIE88329.1 - 3.2 7.7 10.6 0.24 11.3 0.4 2.8 2 2 1 3 3 3 0 RNA polymerase Rpb4 YL1 PF05764.8 EIE88329.1 - 4.4 6.8 14.8 0.05 13.2 4.3 2.0 2 0 0 2 2 2 0 YL1 nuclear protein DeoC PF01791.4 EIE88330.1 - 4.2e-46 157.1 2.9 4.8e-46 156.9 2.0 1.0 1 0 0 1 1 1 1 DeoC/LacD family aldolase FMN_dh PF01070.13 EIE88330.1 - 0.038 12.8 0.2 0.89 8.3 0.0 2.1 1 1 0 2 2 2 0 FMN-dependent dehydrogenase DUF735 PF05246.6 EIE88330.1 - 0.049 13.3 0.1 0.098 12.3 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF735) His_biosynth PF00977.16 EIE88330.1 - 0.053 12.7 0.0 0.17 11.1 0.0 1.5 1 1 0 1 1 1 0 Histidine biosynthesis protein Peptidase_M57 PF12388.3 EIE88330.1 - 0.063 12.5 0.1 0.089 12.1 0.0 1.3 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase BCS1_N PF08740.6 EIE88331.1 - 7.5e-17 61.5 5.1 7.3e-14 51.8 0.1 2.4 2 1 0 3 3 3 2 BCS1 N terminal DUF3808 PF10300.4 EIE88332.1 - 6.9e-59 199.6 3.3 1.8e-57 194.9 0.7 2.2 1 1 0 2 2 2 2 Protein of unknown function (DUF3808) TPR_2 PF07719.12 EIE88332.1 - 0.012 15.4 1.0 9.7 6.3 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 EIE88332.1 - 0.017 15.0 0.0 0.081 12.8 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Zn_Tnp_IS1595 PF12760.2 EIE88333.1 - 0.057 13.2 4.5 0.11 12.3 3.1 1.4 1 1 0 1 1 1 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.5 EIE88333.1 - 0.53 10.2 2.7 16 5.5 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain DUF3716 PF12511.3 EIE88333.1 - 0.76 9.4 5.6 1.5 8.5 3.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3716) ZZ PF00569.12 EIE88333.1 - 0.92 9.1 5.0 1.3 8.6 1.4 2.2 2 0 0 2 2 2 0 Zinc finger, ZZ type Zn_Tnp_IS1 PF03811.8 EIE88333.1 - 3.2 7.3 6.0 15 5.1 0.2 2.4 2 0 0 2 2 2 0 InsA N-terminal domain PI31_Prot_N PF11566.3 EIE88334.1 - 3e-11 43.1 0.0 5.3e-05 22.8 0.0 2.1 1 1 1 2 2 2 2 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.6 EIE88334.1 - 1.3e-10 41.7 15.5 1.3e-10 41.7 10.8 2.7 2 1 1 3 3 3 1 PI31 proteasome regulator E1-E2_ATPase PF00122.15 EIE88335.1 - 1.7e-42 145.0 0.5 6.3e-38 130.0 0.0 2.6 1 1 1 2 2 2 2 E1-E2 ATPase Hydrolase PF00702.21 EIE88335.1 - 1.3e-28 100.9 0.0 2e-27 96.9 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 EIE88335.1 - 4.7e-26 91.4 1.4 4.7e-26 91.4 1.0 2.8 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase_like2 PF13246.1 EIE88335.1 - 1.5e-16 60.1 0.0 3.3e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EIE88335.1 - 1.3e-12 48.3 0.0 3.5e-12 46.8 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EIE88335.1 - 1e-08 34.5 0.0 1.3e-07 31.0 0.0 2.4 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EIE88335.1 - 6.4e-05 22.6 0.4 0.00038 20.1 0.3 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Piwi PF02171.12 EIE88336.1 - 8.7e-104 346.7 0.0 1.2e-103 346.2 0.0 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 EIE88336.1 - 2.9e-27 94.6 0.1 6.2e-27 93.5 0.1 1.5 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 EIE88336.1 - 1.1e-17 63.1 0.0 2.3e-17 62.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PPAK PF02818.10 EIE88337.1 - 0.052 13.4 8.1 0.1 12.5 5.6 1.4 1 0 0 1 1 1 0 PPAK motif DUF3608 PF12257.3 EIE88339.1 - 1.5e-66 224.2 1.3 1.3e-65 221.0 0.9 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3608) DEP PF00610.16 EIE88339.1 - 5.5e-20 70.8 0.1 1.6e-19 69.3 0.0 1.9 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) HLH PF00010.21 EIE88340.1 - 5.7e-13 48.3 2.6 1.1e-12 47.4 1.8 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PhoU_div PF01865.11 EIE88340.1 - 0.01 15.0 0.7 0.037 13.2 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function DUF47 DUF591 PF04569.9 EIE88340.1 - 0.047 13.7 2.7 0.083 12.9 1.9 1.4 1 0 0 1 1 1 0 Protein of unknown function Myc-LZ PF02344.10 EIE88340.1 - 0.083 12.5 5.8 2.6 7.7 0.4 2.5 2 0 0 2 2 2 0 Myc leucine zipper domain Band_7 PF01145.20 EIE88341.1 - 2.2e-30 105.8 0.5 2.2e-30 105.8 0.3 1.7 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 EIE88341.1 - 0.092 12.2 0.0 0.23 10.9 0.0 1.7 1 0 0 1 1 1 0 SPFH domain-Band 7 family LPP20 PF02169.11 EIE88341.1 - 0.43 10.7 4.4 3 7.9 3.0 2.5 1 1 0 1 1 1 0 LPP20 lipoprotein SCP2 PF02036.12 EIE88342.1 - 2.5e-06 27.7 0.0 3.1e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 SCP-2 sterol transfer family Nucleoporin_N PF08801.6 EIE88343.1 - 1e-40 139.7 0.5 1.9e-40 138.9 0.3 1.4 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.9 EIE88343.1 - 3.1e-34 118.4 7.2 4.6e-34 117.9 5.0 1.2 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal SpoOE-like PF09388.5 EIE88343.1 - 0.02 14.4 0.0 0.1 12.1 0.0 2.2 2 0 0 2 2 2 0 Spo0E like sporulation regulatory protein Carn_acyltransf PF00755.15 EIE88346.1 - 4.3e-186 619.5 0.1 4.9e-186 619.3 0.1 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Tropomyosin PF00261.15 EIE88346.1 - 0.033 13.2 0.3 0.16 11.0 0.1 2.2 2 0 0 2 2 2 0 Tropomyosin ApbA_C PF08546.6 EIE88347.1 - 8.9e-29 100.0 0.4 1.4e-28 99.3 0.3 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 EIE88347.1 - 1.1e-28 99.6 0.1 1.5e-28 99.1 0.1 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 EIE88347.1 - 3.5e-07 30.0 0.1 6.6e-07 29.1 0.1 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_10 PF13460.1 EIE88347.1 - 0.00041 20.4 0.0 0.0006 19.8 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3HCDH_N PF02737.13 EIE88347.1 - 0.00091 18.9 0.0 0.002 17.7 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.22 EIE88347.1 - 0.0013 19.1 0.0 0.0032 17.8 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EIE88347.1 - 0.0088 16.0 0.0 0.038 13.9 0.0 2.1 2 0 0 2 2 2 1 TrkA-N domain NAD_binding_2 PF03446.10 EIE88347.1 - 0.011 15.6 0.0 0.031 14.1 0.0 1.9 2 1 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 EIE88347.1 - 0.028 13.5 0.0 0.088 11.9 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NmrA PF05368.8 EIE88347.1 - 0.071 12.3 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family F420_oxidored PF03807.12 EIE88347.1 - 0.076 13.4 0.0 0.2 12.1 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DAO PF01266.19 EIE88347.1 - 0.13 11.1 0.0 0.28 10.0 0.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase Dor1 PF04124.7 EIE88348.1 - 4.9e-57 192.9 9.2 8e-57 192.2 6.4 1.3 1 1 0 1 1 1 1 Dor1-like family Vps51 PF08700.6 EIE88348.1 - 6.6e-05 22.6 3.0 0.00021 21.0 2.1 1.9 1 0 0 1 1 1 1 Vps51/Vps67 DUF3793 PF12672.2 EIE88348.1 - 0.0072 15.9 0.5 0.38 10.3 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3793) Sec5 PF15469.1 EIE88348.1 - 0.03 14.0 5.4 0.074 12.7 2.1 2.6 1 1 1 2 2 2 0 Exocyst complex component Sec5 UPF0184 PF03670.8 EIE88348.1 - 0.078 13.1 0.9 0.23 11.6 0.6 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) DDE_3 PF13358.1 EIE88349.1 - 3.5e-29 101.4 0.0 4.3e-29 101.1 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE88349.1 - 0.11 12.6 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain Cytidylate_kin PF02224.13 EIE88350.1 - 7.2e-37 126.2 2.5 3.8e-30 104.3 0.5 2.1 1 1 1 2 2 2 2 Cytidylate kinase AAA_17 PF13207.1 EIE88350.1 - 9.3e-13 49.0 0.0 6.3e-12 46.3 0.0 2.1 1 1 1 2 2 2 1 AAA domain Cytidylate_kin2 PF13189.1 EIE88350.1 - 1.7e-06 28.0 0.1 0.00094 19.1 0.0 2.2 2 0 0 2 2 2 2 Cytidylate kinase-like family AAA_18 PF13238.1 EIE88350.1 - 3.7e-05 24.0 0.1 0.00013 22.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EIE88350.1 - 0.00045 20.1 0.1 0.0023 17.8 0.0 2.1 2 1 0 2 2 2 1 AAA domain SKI PF01202.17 EIE88350.1 - 0.004 17.0 0.1 0.0081 16.0 0.1 1.5 1 0 0 1 1 1 1 Shikimate kinase ADK PF00406.17 EIE88350.1 - 0.0045 16.8 0.0 0.01 15.7 0.0 1.6 1 0 0 1 1 1 1 Adenylate kinase Poly_export PF02563.11 EIE88350.1 - 0.02 14.6 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis/export protein ABC_tran PF00005.22 EIE88350.1 - 0.039 14.2 0.1 0.42 10.8 0.0 2.2 1 1 0 1 1 1 0 ABC transporter CoaE PF01121.15 EIE88350.1 - 0.049 13.0 0.0 0.09 12.1 0.0 1.4 1 0 0 1 1 1 0 Dephospho-CoA kinase AAA_28 PF13521.1 EIE88350.1 - 0.13 12.2 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF802 PF05650.6 EIE88351.1 - 0.045 13.8 0.3 0.07 13.2 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF802) Cpn60_TCP1 PF00118.19 EIE88352.1 - 4e-146 487.4 8.4 4.5e-146 487.2 5.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Erv26 PF04148.8 EIE88354.1 - 2.9e-30 105.2 10.7 7e-30 103.9 7.4 1.6 1 1 0 1 1 1 1 Transmembrane adaptor Erv26 ATP_bind_4 PF01902.12 EIE88355.1 - 7.8e-37 126.7 0.0 1.4e-36 125.9 0.0 1.4 1 1 0 1 1 1 1 ATP-binding region P22_AR_C PF10548.4 EIE88355.1 - 0.11 12.3 0.2 2.5 8.0 0.0 2.8 3 0 0 3 3 3 0 P22AR C-terminal domain Transketolase_N PF00456.16 EIE88356.1 - 6.6e-151 501.8 0.0 9.2e-151 501.3 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 EIE88356.1 - 1.6e-43 148.2 0.0 5.4e-43 146.5 0.0 1.9 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EIE88356.1 - 4.3e-13 49.2 0.0 1.1e-12 48.0 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 EIE88356.1 - 2.6e-07 29.8 0.0 0.00011 21.2 0.0 2.2 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.15 EIE88356.1 - 0.001 17.8 0.0 0.0039 15.9 0.0 1.8 2 0 0 2 2 2 1 Dehydrogenase E1 component UPF0066 PF01980.11 EIE88356.1 - 0.063 13.2 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0066 Terpene_synth PF01397.16 EIE88356.1 - 0.066 12.5 0.1 0.15 11.3 0.0 1.6 2 0 0 2 2 2 0 Terpene synthase, N-terminal domain GATase_2 PF00310.16 EIE88357.1 - 5.1e-21 74.7 0.0 7.6e-21 74.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.1 EIE88357.1 - 3.4e-17 62.6 0.0 7.4e-17 61.5 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EIE88357.1 - 1.5e-15 57.0 0.0 2.6e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 EIE88357.1 - 2.7e-11 43.2 1.1 4.2e-11 42.6 0.1 1.8 2 0 0 2 2 2 1 Phosphoribosyl transferase domain GATase_4 PF13230.1 EIE88357.1 - 1e-07 30.9 0.0 1.7e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Pkinase PF00069.20 EIE88358.1 - 4.2e-34 117.8 0.0 4.2e-34 117.8 0.0 2.7 2 1 0 2 2 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE88358.1 - 6.3e-23 81.1 0.0 1.4e-22 80.0 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase CAF-1_p150 PF11600.3 EIE88358.1 - 0.00015 21.2 61.6 0.00025 20.4 42.7 1.4 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Mitofilin PF09731.4 EIE88358.1 - 0.01 14.5 31.6 0.013 14.2 21.9 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein MIP-T3 PF10243.4 EIE88358.1 - 0.011 14.2 61.3 0.015 13.7 42.5 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CDC27 PF09507.5 EIE88358.1 - 0.067 12.4 46.5 0.089 11.9 32.3 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Asp-B-Hydro_N PF05279.6 EIE88358.1 - 0.5 10.1 41.3 0.76 9.5 28.6 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region eIF-3_zeta PF05091.7 EIE88358.1 - 0.59 8.6 30.0 1.1 7.7 20.8 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SAPS PF04499.10 EIE88358.1 - 1 7.9 24.9 1.7 7.1 17.2 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Borrelia_P83 PF05262.6 EIE88358.1 - 3.3 5.8 48.5 4.7 5.3 33.6 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Ycf1 PF05758.7 EIE88358.1 - 6.4 4.3 35.6 9.3 3.8 24.7 1.2 1 0 0 1 1 1 0 Ycf1 HMG_CoA_synt_C PF08540.5 EIE88360.1 - 1.7e-101 339.4 4.3 2.3e-101 339.0 2.9 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 EIE88360.1 - 1.7e-87 291.4 0.3 2.8e-87 290.7 0.2 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal ACP_syn_III_C PF08541.5 EIE88360.1 - 0.0019 18.1 0.1 1.2 9.2 0.0 2.4 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal FAD-SLDH PF12318.3 EIE88361.1 - 0.024 14.3 1.3 0.045 13.4 0.9 1.4 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase DivIC PF04977.10 EIE88361.1 - 0.026 14.0 5.9 0.049 13.1 4.1 1.4 1 0 0 1 1 1 0 Septum formation initiator DUF3373 PF11853.3 EIE88361.1 - 0.029 12.9 1.1 0.042 12.3 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) TUDOR PF00567.19 EIE88361.1 - 0.035 13.9 0.2 0.072 12.9 0.1 1.5 1 0 0 1 1 1 0 Tudor domain Gp-FAR-1 PF05823.7 EIE88361.1 - 0.039 13.9 0.2 0.039 13.9 0.2 2.1 2 0 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF3829 PF12889.2 EIE88361.1 - 0.2 10.7 8.5 0.25 10.5 5.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3829) Pec_lyase_N PF04431.8 EIE88361.1 - 0.39 10.8 3.0 13 5.9 0.0 3.0 3 0 0 3 3 3 0 Pectate lyase, N terminus YvrJ PF12841.2 EIE88361.1 - 2.7 7.3 4.6 19 4.6 0.3 2.4 2 0 0 2 2 2 0 YvrJ protein family Activator_LAG-3 PF11498.3 EIE88361.1 - 7.6 5.1 14.9 12 4.5 10.3 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Rad17 PF03215.10 EIE88362.1 - 2.3e-11 43.0 0.1 1e-08 34.3 0.0 2.0 1 1 1 2 2 2 2 Rad17 cell cycle checkpoint protein NTF2 PF02136.15 EIE88363.1 - 4.4e-34 117.3 0.1 4.8e-34 117.2 0.1 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Thioredoxin PF00085.15 EIE88364.1 - 1.7e-63 210.8 0.1 3.5e-32 110.1 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_7 PF13899.1 EIE88364.1 - 4.3e-14 52.2 0.0 4e-07 29.9 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 EIE88364.1 - 1.6e-12 47.6 1.6 7.6e-05 22.8 0.1 3.7 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EIE88364.1 - 8.9e-11 41.7 0.3 0.00031 20.7 0.0 3.2 3 1 1 4 4 4 2 Thioredoxin-like AhpC-TSA PF00578.16 EIE88364.1 - 2.3e-08 33.7 0.1 0.003 17.2 0.0 2.4 2 0 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.5 EIE88364.1 - 6.8e-07 28.9 0.5 0.036 13.6 0.0 2.3 2 0 0 2 2 2 2 Redoxin Thioredoxin_6 PF13848.1 EIE88364.1 - 2.4e-05 24.2 0.1 0.54 10.0 0.0 4.2 2 1 2 4 4 4 2 Thioredoxin-like domain Thioredoxin_4 PF13462.1 EIE88364.1 - 0.001 19.0 0.4 0.47 10.4 0.0 2.7 3 0 0 3 3 3 2 Thioredoxin UL11 PF11094.3 EIE88364.1 - 0.0065 16.2 0.2 0.22 11.3 0.0 2.4 2 0 0 2 2 2 1 Membrane-associated tegument protein TraF PF13728.1 EIE88364.1 - 0.015 14.7 0.0 0.94 8.9 0.0 2.3 2 0 0 2 2 2 0 F plasmid transfer operon protein Thioredoxin_9 PF14595.1 EIE88364.1 - 0.015 14.8 0.1 1.1 8.8 0.0 2.5 2 0 0 2 2 2 0 Thioredoxin CMD PF02627.15 EIE88365.1 - 0.12 12.2 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 Carboxymuconolactone decarboxylase family Borrelia_orfA PF02414.10 EIE88370.1 - 0.0089 15.1 5.6 0.0089 15.1 3.9 1.7 1 1 0 1 1 1 1 Borrelia ORF-A PACT_coil_coil PF10495.4 EIE88370.1 - 0.065 13.1 1.4 0.39 10.6 1.0 2.3 1 1 0 1 1 1 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein Herpes_capsid PF06112.6 EIE88370.1 - 0.15 12.1 4.5 0.26 11.3 3.1 1.5 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein TerB-C PF15615.1 EIE88370.1 - 0.82 9.9 8.5 0.034 14.3 1.7 1.8 2 0 0 2 2 2 0 TerB-C domain IncA PF04156.9 EIE88370.1 - 1.4 8.4 15.7 2.7 7.5 10.9 1.4 1 0 0 1 1 1 0 IncA protein CoA_binding PF02629.14 EIE88371.1 - 4.2e-30 104.0 2.9 6.4e-30 103.5 0.4 2.4 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 EIE88371.1 - 3.2e-23 82.0 0.2 6.5e-23 81.0 0.1 1.5 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 EIE88371.1 - 5e-07 29.4 0.0 1e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 EIE88371.1 - 0.00038 20.6 0.4 0.0011 19.1 0.1 1.9 2 1 1 3 3 3 1 CoA binding domain GFO_IDH_MocA PF01408.17 EIE88371.1 - 0.023 15.2 0.1 0.056 13.9 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Ribosomal_L28e PF01778.12 EIE88372.1 - 7.7e-35 119.8 4.4 9.8e-35 119.4 3.1 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family B12D PF06522.6 EIE88373.1 - 3.1e-16 58.8 0.0 3.4e-16 58.7 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit Ribosomal_S11 PF00411.14 EIE88374.1 - 7.8e-26 90.4 0.4 9e-26 90.2 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S11 eIF-5a PF01287.15 EIE88376.1 - 9.2e-30 102.4 0.8 1.4e-29 101.8 0.6 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 EIE88376.1 - 0.00043 19.8 0.4 0.00079 19.0 0.3 1.4 1 0 0 1 1 1 1 KOW motif EFP_N PF08207.7 EIE88376.1 - 0.061 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain PH PF00169.24 EIE88377.1 - 5.2e-14 52.3 0.7 5.2e-14 52.3 0.5 1.9 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 EIE88377.1 - 3.9e-06 27.0 1.5 3.9e-06 27.0 1.1 2.8 2 2 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.1 EIE88377.1 - 3.6e-05 23.7 2.9 6.3e-05 22.9 0.6 2.4 2 1 0 2 2 2 1 Pleckstrin homology domain PH_9 PF15410.1 EIE88377.1 - 0.16 12.1 3.9 0.11 12.6 0.3 2.3 2 2 0 2 2 2 0 Pleckstrin homology domain RhoGAP PF00620.22 EIE88378.1 - 1e-40 138.8 0.6 2e-40 137.8 0.4 1.5 1 0 0 1 1 1 1 RhoGAP domain PIF1 PF05970.9 EIE88379.1 - 3.1e-29 102.0 0.2 7.2e-22 77.8 0.1 2.5 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 EIE88379.1 - 3.5e-19 69.1 0.0 5.5e-19 68.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 EIE88379.1 - 7.4e-05 22.3 0.0 0.0003 20.3 0.0 2.0 1 1 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 EIE88379.1 - 0.00021 20.9 0.0 0.00037 20.1 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 EIE88379.1 - 0.00074 19.6 0.0 0.0015 18.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EIE88379.1 - 0.001 19.3 0.1 0.0022 18.2 0.0 1.8 1 1 0 1 1 1 1 ABC transporter AAA_17 PF13207.1 EIE88379.1 - 0.011 16.5 0.0 0.027 15.3 0.0 1.9 2 1 0 2 2 1 0 AAA domain AAA_14 PF13173.1 EIE88379.1 - 0.013 15.3 0.0 0.036 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EIE88379.1 - 0.031 13.7 0.0 0.054 12.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.10 EIE88379.1 - 0.038 13.8 0.3 0.093 12.5 0.1 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit PLATZ PF04640.9 EIE88379.1 - 0.041 14.0 0.1 0.09 12.9 0.1 1.6 1 0 0 1 1 1 0 PLATZ transcription factor FtsK_SpoIIIE PF01580.13 EIE88379.1 - 0.046 13.1 0.1 0.12 11.8 0.0 1.7 1 1 1 2 2 2 0 FtsK/SpoIIIE family DEAD PF00270.24 EIE88379.1 - 0.083 12.3 0.2 0.24 10.8 0.1 2.0 1 1 0 1 1 1 0 DEAD/DEAH box helicase T2SE PF00437.15 EIE88379.1 - 0.085 11.7 0.0 0.15 10.9 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_28 PF13521.1 EIE88379.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF2953 PF11167.3 EIE88379.1 - 0.13 12.2 0.0 0.3 11.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2953) DUF853 PF05872.7 EIE88379.1 - 0.13 10.5 0.0 0.2 9.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) AAA PF00004.24 EIE88379.1 - 0.14 12.4 0.0 0.31 11.2 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EIE88379.1 - 0.14 12.0 0.0 0.33 10.9 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain Helitron_like_N PF14214.1 EIE88380.1 - 1.6e-08 34.4 0.1 2.1e-08 34.0 0.1 1.2 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Glyco_hydro_16 PF00722.16 EIE88384.1 - 1.6e-38 131.8 4.1 2.2e-38 131.4 2.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DEAD PF00270.24 EIE88385.1 - 4e-44 150.0 0.0 1.6e-43 148.0 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIE88385.1 - 2e-26 91.6 0.1 4e-26 90.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIE88385.1 - 0.00021 21.1 0.0 0.00056 19.7 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 EIE88385.1 - 0.018 13.4 0.0 0.12 10.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) DUF3035 PF11233.3 EIE88385.1 - 0.08 12.9 0.1 2.6 8.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3035) Aa_trans PF01490.13 EIE88386.1 - 1.3e-47 162.1 21.7 1.7e-47 161.8 15.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.1 EIE88386.1 - 1.4e-13 50.1 29.1 1.9e-13 49.7 20.2 1.1 1 0 0 1 1 1 1 Amino acid permease Spore_permease PF03845.8 EIE88386.1 - 9.2e-07 27.8 17.7 2e-06 26.6 12.3 1.6 1 1 0 1 1 1 1 Spore germination protein DUF3422 PF11902.3 EIE88386.1 - 1.7 7.4 4.1 3 6.5 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3422) OrfB_Zn_ribbon PF07282.6 EIE88387.1 - 0.076 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain DUF755 PF05501.6 EIE88387.1 - 0.17 11.9 4.8 0.21 11.6 2.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF755) JmjC PF02373.17 EIE88389.1 - 9.5e-42 141.8 0.5 9.5e-42 141.8 0.3 2.5 3 0 0 3 3 3 1 JmjC domain, hydroxylase PLU-1 PF08429.6 EIE88389.1 - 6.7e-27 94.2 16.7 8.4e-25 87.3 8.1 2.3 2 0 0 2 2 2 2 PLU-1-like protein PHD PF00628.24 EIE88389.1 - 9.1e-21 73.2 26.2 2.3e-12 46.3 3.7 3.4 3 0 0 3 3 3 2 PHD-finger ARID PF01388.16 EIE88389.1 - 2.2e-20 72.2 0.0 5.7e-20 70.9 0.0 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain JmjN PF02375.12 EIE88389.1 - 6.9e-17 60.6 2.1 1.7e-16 59.3 0.8 2.3 2 0 0 2 2 2 1 jmjN domain zf-C5HC2 PF02928.11 EIE88389.1 - 1.4e-12 47.5 13.3 1.4e-12 47.5 9.2 2.8 2 0 0 2 2 2 1 C5HC2 zinc finger zf-PHD-like PF15446.1 EIE88389.1 - 0.041 13.1 11.6 0.047 12.9 1.2 3.0 3 0 0 3 3 3 0 PHD/FYVE-zinc-finger like domain Phage_term_smal PF05944.7 EIE88389.1 - 0.079 12.6 1.3 42 3.8 0.1 3.3 3 0 0 3 3 3 0 Phage small terminase subunit DUF2024 PF09630.5 EIE88389.1 - 1.7 8.3 7.0 6 6.6 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF2024) SIR2 PF02146.12 EIE88390.1 - 1.5e-28 99.7 0.0 1.8e-28 99.4 0.0 1.1 1 0 0 1 1 1 1 Sir2 family Lar_restr_allev PF14354.1 EIE88390.1 - 0.1 12.9 0.0 0.91 9.8 0.0 2.1 2 0 0 2 2 2 0 Restriction alleviation protein Lar DUF364 PF04016.7 EIE88390.1 - 0.14 11.5 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF364) Ctf8 PF09696.5 EIE88391.1 - 1.5e-14 53.8 0.0 3.5e-14 52.6 0.0 1.6 1 1 0 1 1 1 1 Ctf8 RepB-RCR_reg PF10723.4 EIE88392.1 - 0.087 12.5 0.0 0.1 12.3 0.0 1.1 1 0 0 1 1 1 0 Replication regulatory protein RepB DZR PF12773.2 EIE88392.1 - 0.61 9.9 5.7 6 6.7 4.2 1.9 1 1 1 2 2 2 0 Double zinc ribbon Zn_Tnp_IS1595 PF12760.2 EIE88392.1 - 3.1 7.6 8.5 4.7 7.1 2.6 2.1 2 0 0 2 2 2 0 Transposase zinc-ribbon domain ZZ PF00569.12 EIE88392.1 - 8.4 6.0 10.4 2.4e+02 1.3 7.2 2.3 1 1 0 1 1 1 0 Zinc finger, ZZ type zf-RVT PF13966.1 EIE88394.1 - 1.6e-07 31.5 1.9 2.3e-07 31.0 1.3 1.3 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase YopR_core PF09025.5 EIE88394.1 - 0.14 12.1 0.0 0.28 11.1 0.0 1.4 2 0 0 2 2 2 0 YopR Core RVT_1 PF00078.22 EIE88395.1 - 0.00026 20.4 0.0 0.0004 19.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ank_4 PF13637.1 EIE88398.1 - 6.5e-15 55.1 0.3 9.7e-08 32.3 0.0 3.1 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EIE88398.1 - 1.1e-13 51.3 0.3 4.3e-06 26.9 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 EIE88398.1 - 3.4e-12 45.5 0.0 9.9e-05 21.9 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 EIE88398.1 - 4.9e-09 35.5 0.1 0.017 15.2 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 EIE88398.1 - 1.1e-07 31.8 0.0 0.028 14.6 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) KilA-N PF04383.8 EIE88398.1 - 8.8e-05 22.0 0.0 0.00069 19.2 0.0 2.5 1 1 0 1 1 1 1 KilA-N domain Sec61_beta PF03911.11 EIE88399.1 - 1.4e-17 63.1 0.4 1.8e-17 62.8 0.3 1.1 1 0 0 1 1 1 1 Sec61beta family DDR PF08841.5 EIE88400.1 - 0.085 11.6 0.1 0.085 11.6 0.1 1.1 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain dUTPase_2 PF08761.6 EIE88400.1 - 0.099 12.7 0.1 0.11 12.5 0.1 1.1 1 0 0 1 1 1 0 dUTPase Glycogen_syn PF05693.8 EIE88401.1 - 1.4e-300 998.1 0.3 3.9e-234 778.6 0.7 2.0 1 1 1 2 2 2 2 Glycogen synthase Glycos_transf_1 PF00534.15 EIE88401.1 - 1.5e-08 34.2 0.0 4e-05 23.0 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EIE88401.1 - 0.082 13.0 0.0 0.25 11.4 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain Cullin_binding PF03556.10 EIE88402.1 - 6.2e-18 65.0 0.5 7.3e-18 64.8 0.3 1.0 1 0 0 1 1 1 1 Cullin binding NDK PF00334.14 EIE88403.1 - 3.7e-27 94.7 0.0 4.2e-27 94.5 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase ETC_C1_NDUFA4 PF04800.7 EIE88403.1 - 0.046 13.5 0.0 0.081 12.7 0.0 1.4 1 0 0 1 1 1 0 ETC complex I subunit conserved region PQ-loop PF04193.9 EIE88404.1 - 1.2e-18 66.3 4.2 2.7e-18 65.2 0.8 2.3 2 0 0 2 2 2 1 PQ loop repeat E1_dh PF00676.15 EIE88406.1 - 4.7e-120 399.8 0.1 5.6e-120 399.5 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 EIE88406.1 - 0.0059 15.5 0.0 0.012 14.5 0.0 1.6 1 1 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Beta_elim_lyase PF01212.16 EIE88406.1 - 0.01 15.0 0.0 1.1 8.3 0.0 2.2 2 0 0 2 2 2 0 Beta-eliminating lyase KRTAP7 PF15034.1 EIE88406.1 - 0.042 14.5 4.0 0.1 13.2 0.1 2.7 2 1 0 2 2 2 0 KRTAP type 7 family Cupin_8 PF13621.1 EIE88407.1 - 4.5e-43 147.5 0.2 6.7e-43 146.9 0.1 1.3 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 EIE88407.1 - 1.4e-11 44.2 0.1 3.3e-11 43.0 0.1 1.6 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.17 EIE88407.1 - 2.3e-05 24.6 0.1 6.6e-05 23.1 0.1 1.9 1 1 0 1 1 1 1 JmjC domain, hydroxylase DUF1971 PF09313.6 EIE88407.1 - 0.093 12.4 0.0 0.59 9.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1971) PRD PF00874.15 EIE88408.1 - 0.016 15.3 1.0 0.49 10.5 0.0 2.8 3 0 0 3 3 3 0 PRD domain FH2 PF02181.18 EIE88410.1 - 1.8e-79 267.3 6.5 1.8e-79 267.3 4.5 2.7 3 0 0 3 3 3 2 Formin Homology 2 Domain Drf_FH3 PF06367.11 EIE88410.1 - 8.7e-45 152.5 13.6 1.4e-43 148.6 3.9 3.1 2 1 1 3 3 3 2 Diaphanous FH3 Domain Drf_GBD PF06371.8 EIE88410.1 - 3e-30 104.9 0.9 3e-30 104.9 0.6 3.3 3 1 0 3 3 3 1 Diaphanous GTPase-binding Domain Apo-CII PF05355.6 EIE88410.1 - 0.018 14.8 0.8 0.34 10.8 0.1 2.6 2 0 0 2 2 2 0 Apolipoprotein C-II DUF4250 PF14056.1 EIE88410.1 - 0.051 13.3 4.2 0.19 11.4 0.1 3.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4250) Metallophos PF00149.23 EIE88411.1 - 3e-11 43.0 0.0 3.3e-06 26.6 0.0 2.4 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase PPP5 PF08321.7 EIE88411.1 - 0.071 13.1 0.0 0.21 11.6 0.0 1.8 2 0 0 2 2 2 0 PPP5 TPR repeat region PXA PF02194.10 EIE88412.1 - 2.8e-46 157.4 1.3 2.8e-46 157.4 0.9 2.8 3 0 0 3 3 3 1 PXA domain RGS PF00615.14 EIE88412.1 - 4.2e-20 72.0 8.2 2.3e-19 69.6 2.7 3.0 2 0 0 2 2 2 1 Regulator of G protein signaling domain PX PF00787.19 EIE88412.1 - 1.2e-19 70.1 0.5 7.5e-19 67.5 0.0 2.7 3 0 0 3 3 3 1 PX domain Nexin_C PF08628.7 EIE88412.1 - 1.3e-16 60.6 0.2 1.3e-16 60.6 0.2 3.9 5 0 0 5 5 5 1 Sorting nexin C terminal Shisa PF13908.1 EIE88413.1 - 0.00019 21.6 0.5 0.00022 21.4 0.3 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Herpes_gE PF02480.11 EIE88413.1 - 0.0019 16.5 0.0 0.0019 16.5 0.0 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E RCR PF12273.3 EIE88413.1 - 0.0061 17.1 6.4 0.014 15.9 4.4 1.5 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red WBP-1 PF11669.3 EIE88413.1 - 0.012 15.6 0.3 0.016 15.2 0.2 1.1 1 0 0 1 1 1 0 WW domain-binding protein 1 EphA2_TM PF14575.1 EIE88413.1 - 0.016 15.5 0.1 0.023 15.0 0.1 1.2 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF2668 PF10873.3 EIE88413.1 - 0.017 15.3 1.6 0.019 15.1 1.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2668) DUF2561 PF10812.3 EIE88413.1 - 0.017 14.7 0.0 0.017 14.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) Chordopox_A13L PF05961.6 EIE88413.1 - 0.074 13.0 0.2 0.15 11.9 0.0 1.6 2 0 0 2 2 2 0 Chordopoxvirus A13L protein OrfB_Zn_ribbon PF07282.6 EIE88414.1 - 5e-08 32.4 4.0 1.3e-07 31.1 2.7 1.8 1 0 0 1 1 1 1 Putative transposase DNA-binding domain Stanniocalcin PF03298.8 EIE88414.1 - 0.0081 15.1 0.1 0.0081 15.1 0.1 2.7 2 1 0 2 2 2 1 Stanniocalcin family DUF4298 PF14131.1 EIE88414.1 - 0.41 10.5 9.8 0.75 9.7 0.2 4.1 3 1 1 4 4 4 0 Domain of unknown function (DUF4298) DUF2207 PF09972.4 EIE88415.1 - 6.6 5.2 8.2 0.12 10.9 0.4 1.7 1 1 0 2 2 2 0 Predicted membrane protein (DUF2207) DDE_3 PF13358.1 EIE88416.1 - 2.7e-14 53.1 0.0 3.5e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Ebp2 PF05890.7 EIE88417.1 - 3.4e-31 108.5 15.5 7.8e-31 107.3 10.8 1.4 1 1 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 Phlebovirus_NSM PF07246.6 EIE88417.1 - 0.57 9.2 4.7 0.87 8.6 3.3 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DUF3043 PF11241.3 EIE88417.1 - 1.3 8.6 5.5 1.8 8.1 3.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) DUF1510 PF07423.6 EIE88417.1 - 2.5 7.4 8.8 3.6 6.9 6.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) EF1G PF00647.14 EIE88418.1 - 2.4e-43 146.2 0.3 6.1e-43 144.8 0.2 1.7 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_N PF02798.15 EIE88418.1 - 3.1e-12 46.4 0.2 1.4e-11 44.3 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EIE88418.1 - 1.4e-11 44.2 0.2 5.8e-11 42.2 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EIE88418.1 - 1.8e-09 37.3 0.0 4.3e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EIE88418.1 - 8.4e-08 32.3 0.0 2e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EIE88418.1 - 7.4e-07 29.5 0.0 1.8e-06 28.3 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EIE88418.1 - 4.4e-05 23.4 0.0 0.00018 21.4 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Glyco_transf_20 PF00982.16 EIE88419.1 - 1.2e-155 518.6 0.0 1.6e-155 518.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EIE88419.1 - 4.9e-82 274.3 0.0 9.1e-82 273.4 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.7 EIE88419.1 - 1.5e-05 24.7 0.0 0.014 14.9 0.0 2.5 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 EIE88419.1 - 0.00024 21.3 0.0 0.078 13.1 0.0 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF3331 PF11811.3 EIE88419.1 - 0.045 13.3 0.0 0.46 10.0 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3331) Glyco_trans_1_4 PF13692.1 EIE88419.1 - 0.055 13.6 0.1 0.18 11.9 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferases group 1 EMP24_GP25L PF01105.19 EIE88420.1 - 9.2e-32 110.2 0.2 1.1e-31 109.9 0.2 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Pkinase PF00069.20 EIE88421.1 - 2.9e-62 210.1 0.0 4.1e-62 209.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE88421.1 - 2.7e-36 124.9 0.0 4.2e-36 124.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EIE88421.1 - 1.5e-06 27.4 0.0 2.9e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIE88421.1 - 9.9e-05 22.1 0.0 0.00022 21.0 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EIE88421.1 - 0.0015 17.5 0.0 0.0043 16.0 0.0 1.7 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EIE88421.1 - 0.0016 17.8 0.1 0.0035 16.7 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.15 EIE88421.1 - 0.018 14.6 0.2 0.051 13.1 0.1 1.7 1 1 0 1 1 1 0 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.4 EIE88421.1 - 0.036 13.3 0.0 0.07 12.4 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL EcKinase PF02958.15 EIE88421.1 - 0.1 11.7 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase LSM PF01423.17 EIE88422.1 - 2.5e-19 68.5 0.1 2.8e-19 68.4 0.1 1.0 1 0 0 1 1 1 1 LSM domain HORMA PF02301.13 EIE88423.1 - 8.5e-23 80.9 0.6 9.9e-23 80.7 0.4 1.0 1 0 0 1 1 1 1 HORMA domain DUF4478 PF14793.1 EIE88423.1 - 0.021 14.3 0.0 0.027 14.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4478) Pam17 PF08566.5 EIE88424.1 - 2.4e-56 190.1 0.0 2.9e-56 189.8 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 HTH_Tnp_Tc3_2 PF01498.13 EIE88426.1 - 8.2e-18 64.2 0.5 8.2e-18 64.2 0.3 2.5 3 1 1 4 4 4 1 Transposase DDE_3 PF13358.1 EIE88426.1 - 4.3e-09 36.2 1.1 6.6e-08 32.4 0.2 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_29 PF13551.1 EIE88426.1 - 1.1e-05 25.5 0.9 8.4e-05 22.6 0.2 2.5 2 1 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.1 EIE88426.1 - 3.5e-05 24.5 2.7 0.014 16.1 0.0 3.8 4 1 0 4 4 4 1 Homeodomain-like domain HTH_23 PF13384.1 EIE88426.1 - 0.00077 19.0 0.3 0.034 13.8 0.0 2.9 3 0 0 3 3 3 1 Homeodomain-like domain HTH_21 PF13276.1 EIE88426.1 - 0.0077 16.2 0.0 0.06 13.3 0.0 2.4 3 0 0 3 3 3 1 HTH-like domain FUR PF01475.14 EIE88426.1 - 0.071 13.0 0.2 6.1 6.7 0.0 2.5 1 1 1 2 2 2 0 Ferric uptake regulator family HTH_28 PF13518.1 EIE88426.1 - 0.075 13.0 0.1 0.27 11.2 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.13 EIE88427.1 - 2.7e-08 33.7 0.2 2.7e-08 33.7 0.1 2.1 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 EIE88427.1 - 0.023 14.8 1.2 0.065 13.3 0.8 1.8 1 1 0 1 1 1 0 Winged helix-turn helix HTH_21 PF13276.1 EIE88427.1 - 0.038 13.9 1.1 0.31 11.0 0.0 2.3 2 0 0 2 2 2 0 HTH-like domain HTH_Tnp_ISL3 PF13542.1 EIE88427.1 - 0.075 12.2 0.7 0.51 9.5 0.1 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_32 PF13565.1 EIE88427.1 - 0.075 13.8 1.4 0.16 12.7 0.4 1.9 2 0 0 2 2 2 0 Homeodomain-like domain DDE_3 PF13358.1 EIE88428.1 - 1.2e-11 44.5 0.2 1.5e-11 44.2 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1033 PF06279.6 EIE88428.1 - 0.033 13.9 0.7 0.057 13.2 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1033) rve PF00665.21 EIE88428.1 - 0.072 13.1 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Integrase core domain HMG_box PF00505.14 EIE88428.1 - 0.11 12.7 0.2 0.3 11.3 0.2 1.8 2 0 0 2 2 2 0 HMG (high mobility group) box Myb_DNA-bind_5 PF13873.1 EIE88428.1 - 0.13 12.1 0.6 10 6.0 0.2 2.5 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain rve PF00665.21 EIE88429.1 - 1.2e-17 64.0 0.0 2.5e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 EIE88429.1 - 4.6e-05 22.8 0.0 0.00014 21.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Sp100 PF03172.8 EIE88429.1 - 0.067 13.1 0.0 0.23 11.4 0.0 1.9 2 0 0 2 2 2 0 Sp100 domain HTH_Tnp_Tc3_2 PF01498.13 EIE88430.1 - 2.6e-05 24.1 0.4 2.6e-05 24.1 0.3 2.0 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.1 EIE88430.1 - 6.5e-05 22.7 0.0 0.00011 21.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease RVT_1 PF00078.22 EIE88431.1 - 0.0082 15.5 0.2 0.0082 15.5 0.1 1.3 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Leader_Erm PF08253.6 EIE88432.1 - 0.33 10.4 0.3 0.33 10.4 0.2 2.1 2 0 0 2 2 2 0 Erm Leader peptide rve PF00665.21 EIE88433.1 - 2.6e-20 72.6 0.0 8.4e-20 71.0 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE88433.1 - 4.2e-11 42.6 0.3 9e-11 41.5 0.2 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE88433.1 - 2.1e-10 40.1 0.4 5.6e-10 38.7 0.3 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Transposase_21 PF02992.9 EIE88434.1 - 9.6e-22 77.1 0.4 3.1e-21 75.5 0.0 1.9 2 0 0 2 2 2 1 Transposase family tnp2 DUF1258 PF06869.7 EIE88434.1 - 0.0049 16.0 0.0 0.01 14.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) TFIIA PF03153.8 EIE88435.1 - 0.048 13.5 6.4 0.058 13.2 4.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DDE_3 PF13358.1 EIE88436.1 - 2.3e-16 59.8 0.0 3.1e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE88436.1 - 1.6e-15 56.8 0.4 5.7e-15 55.1 0.2 1.9 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 EIE88436.1 - 0.017 15.2 0.1 0.089 12.9 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn helix HTH_32 PF13565.1 EIE88436.1 - 0.02 15.6 1.5 2.7 8.8 0.0 3.4 4 0 0 4 4 4 0 Homeodomain-like domain DUF3427 PF11907.3 EIE88436.1 - 0.058 12.3 0.0 0.076 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3427) Transposase_21 PF02992.9 EIE88437.1 - 1.4e-22 79.9 0.1 1.4e-22 79.9 0.1 1.5 2 0 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.1 EIE88438.1 - 6.1e-05 22.4 0.2 0.0001 21.7 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) DDE_3 PF13358.1 EIE88440.1 - 1e-19 70.7 0.2 2e-19 69.7 0.1 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE88440.1 - 8e-16 57.8 1.7 2.3e-15 56.4 0.3 2.3 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 EIE88440.1 - 2.1e-06 27.8 0.5 6.7e-06 26.2 0.2 2.0 2 0 0 2 2 2 1 Winged helix-turn helix HTH_38 PF13936.1 EIE88440.1 - 1e-05 25.0 0.1 2.7e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.1 EIE88440.1 - 5.8e-05 22.5 0.1 0.0023 17.4 0.0 2.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.1 EIE88440.1 - 8.6e-05 23.2 3.5 0.016 15.9 0.1 3.7 4 0 0 4 4 4 1 Homeodomain-like domain HTH_28 PF13518.1 EIE88440.1 - 0.00096 19.1 0.0 0.0046 16.9 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.7 EIE88440.1 - 0.0012 18.2 0.5 0.02 14.3 0.0 2.5 3 0 0 3 3 3 1 Sigma-70, region 4 HTH_21 PF13276.1 EIE88440.1 - 0.0013 18.6 0.3 0.11 12.5 0.0 2.8 3 0 0 3 3 2 1 HTH-like domain HTH_7 PF02796.10 EIE88440.1 - 0.0016 18.2 1.1 0.087 12.6 0.0 2.8 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase LacI PF00356.16 EIE88440.1 - 0.012 15.2 1.7 2.4 7.8 0.2 2.7 3 0 0 3 3 3 0 Bacterial regulatory proteins, lacI family HTH_Tnp_4 PF13613.1 EIE88440.1 - 0.018 14.5 0.1 0.048 13.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease rve PF00665.21 EIE88440.1 - 0.029 14.4 0.1 0.089 12.9 0.0 2.0 2 1 0 2 2 2 0 Integrase core domain CPSase_L_D3 PF02787.14 EIE88440.1 - 0.044 13.5 0.0 0.12 12.1 0.0 1.7 2 0 0 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain HTH_36 PF13730.1 EIE88440.1 - 0.05 13.7 0.3 3.4 7.8 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.1 EIE88440.1 - 0.12 11.5 2.8 7.1 5.8 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 Sigma70_r4 PF04545.11 EIE88440.1 - 0.17 11.2 0.4 0.66 9.3 0.0 2.2 3 0 0 3 3 3 0 Sigma-70, region 4 HTH_17 PF12728.2 EIE88440.1 - 0.47 10.7 2.8 13 6.1 0.1 2.7 3 0 0 3 3 2 0 Helix-turn-helix domain rve PF00665.21 EIE88441.1 - 4.2e-21 75.2 0.0 1.1e-20 73.8 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE88441.1 - 1.1e-15 57.6 0.1 2.2e-15 56.5 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.12 EIE88441.1 - 7.4e-09 35.5 0.1 1.8e-08 34.3 0.1 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein zf-H2C2 PF09337.5 EIE88441.1 - 0.00049 19.4 1.6 0.0012 18.2 1.1 1.7 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger UBN2 PF14223.1 EIE88441.1 - 0.12 12.1 0.0 0.29 10.9 0.0 1.7 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Rpr2 PF04032.11 EIE88443.1 - 0.037 13.8 1.5 2.2 8.2 0.1 2.5 1 1 1 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain FXa_inhibition PF14670.1 EIE88443.1 - 1 9.5 4.0 2 8.6 0.4 2.4 2 0 0 2 2 2 0 Coagulation Factor Xa inhibitory site zf-BED PF02892.10 EIE88443.1 - 1.1 9.1 4.1 2.8 7.7 2.1 2.3 2 1 0 2 2 2 0 BED zinc finger RNA_pol_3_Rpc31 PF11705.3 EIE88444.1 - 0.0022 17.9 13.3 0.0031 17.4 9.2 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 TFIIA PF03153.8 EIE88444.1 - 0.012 15.4 10.3 0.016 15.0 7.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Daxx PF03344.10 EIE88444.1 - 0.025 13.0 12.1 0.027 13.0 8.4 1.1 1 0 0 1 1 1 0 Daxx Family Recombinase PF07508.8 EIE88444.1 - 0.028 14.6 0.3 0.045 13.9 0.2 1.5 1 1 0 1 1 1 0 Recombinase CobT PF06213.7 EIE88444.1 - 0.094 11.8 12.6 0.1 11.6 8.7 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT TFIIF_alpha PF05793.7 EIE88444.1 - 0.1 10.9 20.6 0.027 12.8 12.4 1.3 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.9 EIE88444.1 - 0.27 9.2 10.5 0.28 9.1 7.3 1.1 1 0 0 1 1 1 0 CDC45-like protein ROS_MUCR PF05443.6 EIE88444.1 - 0.33 10.7 4.5 0.74 9.5 0.0 2.5 2 1 0 2 2 2 0 ROS/MUCR transcriptional regulator protein Orbi_VP6 PF01516.11 EIE88444.1 - 0.43 9.5 8.3 0.72 8.8 5.8 1.3 1 0 0 1 1 1 0 Orbivirus helicase VP6 DUF2457 PF10446.4 EIE88444.1 - 0.51 9.0 17.3 0.68 8.6 12.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Rotamase_2 PF13145.1 EIE88444.1 - 0.93 10.1 11.0 0.27 11.8 5.4 1.7 1 1 1 2 2 2 0 PPIC-type PPIASE domain TRAP_alpha PF03896.11 EIE88444.1 - 2.2 7.1 12.9 3.6 6.5 9.0 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Ribosomal_60s PF00428.14 EIE88444.1 - 4.6 7.7 15.5 12 6.4 10.7 1.8 1 1 0 1 1 1 0 60s Acidic ribosomal protein Mito_carr PF00153.22 EIE88445.1 - 7.3e-47 157.0 1.3 9.1e-17 60.5 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein SieB PF14163.1 EIE88445.1 - 0.1 12.1 5.0 0.23 11.0 0.1 2.9 3 0 0 3 3 3 0 Superinfection exclusion protein B ER_lumen_recept PF00810.13 EIE88445.1 - 0.66 10.4 5.0 0.12 12.8 0.5 1.8 2 0 0 2 2 2 0 ER lumen protein retaining receptor ETC_C1_NDUFA4 PF04800.7 EIE88446.1 - 2.2e-31 107.7 0.9 3.1e-31 107.2 0.6 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region Dppa2_A PF14049.1 EIE88446.1 - 0.077 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Dppa2/4 conserved region in higher vertebrates DUF3892 PF13031.1 EIE88446.1 - 0.17 12.3 0.7 0.29 11.5 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3892) Lon_C PF05362.8 EIE88447.1 - 1.4e-20 73.5 0.1 4e-20 71.9 0.0 1.7 2 0 0 2 2 2 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.24 EIE88447.1 - 7.5e-10 39.1 0.0 1.5e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 EIE88447.1 - 0.0076 16.1 0.1 0.021 14.7 0.0 1.8 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_2 PF07724.9 EIE88447.1 - 0.045 13.6 0.0 0.32 10.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) Ran-binding PF05508.6 EIE88448.1 - 3.8e-41 140.9 7.0 8.1e-40 136.5 4.9 2.6 1 1 0 1 1 1 1 RanGTP-binding protein L31 PF09784.4 EIE88448.1 - 0.049 13.7 0.4 0.35 10.9 0.0 2.4 1 1 1 2 2 2 0 Mitochondrial ribosomal protein L31 DUF1664 PF07889.7 EIE88448.1 - 0.058 13.1 0.9 0.17 11.6 0.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Alpha-amylase_C PF02806.13 EIE88449.1 - 2.3e-24 85.3 0.0 5.9e-24 84.0 0.0 1.7 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 EIE88449.1 - 3.7e-17 62.6 0.0 6.2e-12 45.5 0.0 2.2 1 1 1 2 2 2 2 Alpha amylase, catalytic domain CBM_48 PF02922.13 EIE88449.1 - 9.5e-14 51.2 0.1 3.4e-13 49.4 0.1 1.9 2 0 0 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Flp_N PF03930.9 EIE88449.1 - 0.021 14.5 0.2 0.049 13.3 0.1 1.6 1 0 0 1 1 1 0 Recombinase Flp protein N-terminus Fork_head PF00250.13 EIE88450.1 - 4.6e-29 100.3 0.1 7e-29 99.7 0.1 1.2 1 0 0 1 1 1 1 Fork head domain NAD_binding_10 PF13460.1 EIE88451.1 - 4.7e-07 29.9 0.0 0.00013 22.0 0.0 2.2 2 0 0 2 2 2 2 NADH(P)-binding NAD_binding_4 PF07993.7 EIE88451.1 - 1.7e-05 23.8 0.1 0.0023 16.9 0.1 2.1 1 1 1 2 2 2 2 Male sterility protein Semialdhyde_dh PF01118.19 EIE88451.1 - 0.00079 19.7 0.2 0.0057 16.9 0.1 2.2 1 1 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 EIE88451.1 - 0.002 17.5 0.0 0.0031 16.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EIE88451.1 - 0.0037 17.1 0.0 0.0059 16.5 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIE88451.1 - 0.0045 16.6 0.0 0.0062 16.2 0.0 1.3 1 0 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 EIE88451.1 - 0.06 12.3 0.0 0.085 11.8 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Fcf1 PF04900.7 EIE88452.1 - 4.9e-42 142.1 0.7 6.3e-42 141.7 0.5 1.1 1 0 0 1 1 1 1 Fcf1 Porin_3 PF01459.17 EIE88453.1 - 1.6e-63 214.5 5.7 1.8e-63 214.4 3.9 1.0 1 0 0 1 1 1 1 Eukaryotic porin DUF4115 PF13464.1 EIE88453.1 - 0.068 12.8 0.0 18 5.0 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4115) Aa_trans PF01490.13 EIE88454.1 - 8.3e-63 212.2 34.6 9.9e-63 212.0 24.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PH PF00169.24 EIE88455.1 - 0.041 14.0 0.0 0.22 11.7 0.0 2.3 2 1 0 2 2 2 0 PH domain QCR10 PF09796.4 EIE88456.1 - 2.2e-18 65.6 0.0 2.4e-18 65.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) DUF2064 PF09837.4 EIE88456.1 - 0.15 11.6 0.0 0.17 11.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2064) RhoGAP PF00620.22 EIE88457.1 - 1.4e-37 128.6 0.0 2.1e-37 128.0 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain DUF1345 PF07077.6 EIE88458.1 - 0.37 10.3 4.0 1 8.8 2.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1345) FUSC_2 PF13515.1 EIE88458.1 - 0.52 10.2 9.9 0.18 11.7 5.1 1.5 1 1 0 1 1 1 0 Fusaric acid resistance protein-like CitMHS PF03600.11 EIE88458.1 - 0.82 8.1 11.3 0.98 7.9 7.9 1.1 1 0 0 1 1 1 0 Citrate transporter HlyIII PF03006.15 EIE88458.1 - 1.6 8.1 8.5 2.1 7.7 5.9 1.3 1 0 0 1 1 1 0 Haemolysin-III related DUF2207 PF09972.4 EIE88459.1 - 0.37 9.3 3.1 0.43 9.1 2.0 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) SHP PF03579.8 EIE88459.1 - 5.9 6.3 7.8 0.76 9.1 0.9 2.7 2 0 0 2 2 2 0 Small hydrophobic protein OrfB_Zn_ribbon PF07282.6 EIE88460.1 - 5.8e-08 32.2 4.1 1.5e-07 30.9 2.8 1.8 1 0 0 1 1 1 1 Putative transposase DNA-binding domain Stanniocalcin PF03298.8 EIE88460.1 - 0.0081 15.1 0.1 0.0081 15.1 0.1 2.8 3 1 0 3 3 3 1 Stanniocalcin family DUF4298 PF14131.1 EIE88460.1 - 0.085 12.7 9.1 0.75 9.7 0.2 4.2 4 1 1 5 5 5 0 Domain of unknown function (DUF4298) UPF0081 PF03652.10 EIE88460.1 - 0.1 12.7 0.0 0.6 10.2 0.0 2.4 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0081) TPR_11 PF13414.1 EIE88461.1 - 4.4e-43 144.7 39.6 2.4e-10 39.9 0.2 9.8 4 3 5 10 10 10 10 TPR repeat TPR_1 PF00515.23 EIE88461.1 - 3.1e-37 124.6 33.2 1.8e-06 27.3 0.3 13.5 15 0 0 15 15 15 8 Tetratricopeptide repeat TPR_2 PF07719.12 EIE88461.1 - 4.5e-31 104.2 36.4 1.5e-05 24.5 0.4 14.7 16 0 0 16 16 15 8 Tetratricopeptide repeat TPR_19 PF14559.1 EIE88461.1 - 1.3e-30 105.5 23.9 2e-08 34.4 0.0 9.3 5 4 4 10 10 10 6 Tetratricopeptide repeat TPR_16 PF13432.1 EIE88461.1 - 2.7e-29 101.1 26.8 4.6e-07 30.3 0.1 10.7 7 4 4 11 11 11 7 Tetratricopeptide repeat TPR_8 PF13181.1 EIE88461.1 - 1.3e-27 93.4 18.6 0.00015 21.2 0.1 12.5 13 1 0 13 13 13 6 Tetratricopeptide repeat TPR_14 PF13428.1 EIE88461.1 - 8.1e-27 91.2 13.9 0.0025 18.2 0.0 13.0 7 4 7 14 14 14 8 Tetratricopeptide repeat TPR_6 PF13174.1 EIE88461.1 - 4.5e-24 83.1 36.9 0.00016 21.8 0.2 13.4 15 1 0 15 15 14 6 Tetratricopeptide repeat TPR_12 PF13424.1 EIE88461.1 - 2.1e-23 82.0 50.9 3e-06 27.0 0.7 10.4 5 4 8 13 13 13 8 Tetratricopeptide repeat TPR_7 PF13176.1 EIE88461.1 - 2.8e-21 73.5 25.8 0.0017 18.0 0.0 11.4 11 1 1 12 12 11 5 Tetratricopeptide repeat TPR_17 PF13431.1 EIE88461.1 - 3.5e-19 67.3 22.7 0.028 14.5 0.0 13.1 14 0 0 14 14 14 4 Tetratricopeptide repeat Apc3 PF12895.2 EIE88461.1 - 5.5e-13 48.8 46.4 2.1e-06 27.7 1.1 6.9 6 2 1 7 7 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EIE88461.1 - 1e-09 38.1 7.9 0.11 12.3 0.0 6.6 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_15 PF13429.1 EIE88461.1 - 2.5e-06 26.7 25.2 7.9e-05 21.8 0.8 5.2 2 2 3 5 5 5 2 Tetratricopeptide repeat TPPII_N PF12583.3 EIE88461.1 - 5.9e-06 26.4 5.8 0.0013 18.8 0.0 3.4 2 1 0 2 2 2 2 Tripeptidyl peptidase II N terminal TPR_10 PF13374.1 EIE88461.1 - 0.0017 18.2 21.2 0.44 10.5 0.1 8.6 9 0 0 9 9 8 1 Tetratricopeptide repeat PPR_2 PF13041.1 EIE88461.1 - 0.073 13.0 0.1 4.8 7.2 0.0 3.7 4 0 0 4 4 2 0 PPR repeat family TPR_3 PF07720.7 EIE88461.1 - 0.16 11.7 0.1 0.16 11.7 0.1 6.6 7 0 0 7 7 7 0 Tetratricopeptide repeat PC_rep PF01851.17 EIE88462.1 - 4.4e-39 130.5 17.3 1.3e-06 28.2 0.1 9.6 10 0 0 10 10 10 7 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EIE88462.1 - 1.9e-14 53.6 0.5 1.8e-09 37.7 0.0 4.5 2 1 2 4 4 4 2 HEAT repeats HEAT PF02985.17 EIE88462.1 - 2.7e-06 27.0 0.7 2.2 8.5 0.1 5.2 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.1 EIE88462.1 - 0.0019 18.6 1.3 0.41 11.1 0.0 4.6 4 1 2 6 6 6 2 HEAT-like repeat DUF2228 PF10228.4 EIE88462.1 - 0.066 12.7 5.5 0.48 9.9 1.1 2.6 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2228) TFIIA_gamma_N PF02268.11 EIE88463.1 - 2.8e-26 90.8 0.0 4.2e-26 90.2 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.9 EIE88463.1 - 4.4e-26 90.4 1.5 5.9e-26 90.0 1.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit HECT PF00632.20 EIE88464.1 - 3e-95 319.0 0.1 3.9e-95 318.6 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 EIE88464.1 - 3.5e-35 119.4 21.8 2.4e-12 46.4 0.3 3.7 4 0 0 4 4 4 3 WW domain WD40 PF00400.27 EIE88465.1 - 3.6e-54 178.8 7.9 2.9e-08 33.2 0.1 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.2 EIE88465.1 - 3.2e-15 55.5 0.9 3.2e-15 55.5 0.6 1.9 2 0 0 2 2 2 1 F-box-like Nup160 PF11715.3 EIE88465.1 - 1.1e-14 53.5 11.3 0.0004 18.6 0.0 5.8 1 1 3 5 5 5 4 Nucleoporin Nup120/160 F-box PF00646.28 EIE88465.1 - 6.6e-10 38.3 0.3 1.5e-09 37.2 0.2 1.6 1 0 0 1 1 1 1 F-box domain Nucleoporin_N PF08801.6 EIE88465.1 - 0.0014 17.4 3.1 0.63 8.7 0.0 4.2 2 2 2 4 4 4 2 Nup133 N terminal like BBS2_Mid PF14783.1 EIE88465.1 - 0.0033 17.1 0.0 22 4.8 0.0 3.9 2 2 3 5 5 5 0 Ciliary BBSome complex subunit 2, middle region Elongin_A PF06881.6 EIE88465.1 - 0.17 12.2 1.8 0.24 11.8 0.2 2.1 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A RabGAP-TBC PF00566.13 EIE88466.1 - 9.9e-22 77.4 0.2 1.3e-21 77.0 0.1 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain MBF1 PF08523.5 EIE88467.1 - 1.6e-21 76.0 3.0 3e-21 75.1 2.1 1.4 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 EIE88467.1 - 5.8e-14 51.6 0.3 1e-13 50.9 0.2 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.1 EIE88467.1 - 9e-05 22.6 0.0 0.00018 21.6 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.2 EIE88467.1 - 0.00013 21.9 0.1 0.0002 21.3 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain RrnaAD PF00398.15 EIE88467.1 - 0.067 12.1 0.0 0.086 11.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Ribosomal_L19e PF01280.15 EIE88468.1 - 4.4e-60 201.7 10.1 4.4e-60 201.7 7.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L19e Sigma54_DBD PF04552.8 EIE88468.1 - 0.29 10.6 4.7 0.67 9.4 0.1 2.5 3 0 0 3 3 3 0 Sigma-54, DNA binding domain DUF4602 PF15375.1 EIE88468.1 - 0.45 10.5 8.6 0.79 9.7 5.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4602) OmdA PF13376.1 EIE88468.1 - 2.1 8.0 6.8 0.53 9.9 0.4 2.6 1 1 1 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated SpoIIE PF07228.7 EIE88469.1 - 8.4e-15 54.9 0.0 1.1e-14 54.5 0.0 1.1 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 EIE88469.1 - 5.5e-13 48.8 0.0 1.9e-05 24.2 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 EIE88469.1 - 1.3e-09 37.7 0.0 2.1e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C Ribosomal_S3_C PF00189.15 EIE88470.1 - 2.9e-14 53.0 0.1 5.4e-14 52.1 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 EIE88470.1 - 5.2e-14 51.5 0.1 8.7e-14 50.8 0.1 1.4 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.3 EIE88470.1 - 0.0068 16.6 0.0 0.012 15.8 0.0 1.4 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 Oxidored_q6 PF01058.17 EIE88472.1 - 1e-22 80.1 0.1 1.4e-22 79.6 0.1 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Bap31 PF05529.7 EIE88473.1 - 9e-47 159.0 5.9 1e-46 158.8 4.1 1.0 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like Cluap1 PF10234.4 EIE88473.1 - 0.002 17.3 13.3 0.0025 17.0 9.2 1.1 1 0 0 1 1 1 1 Clusterin-associated protein-1 NPV_P10 PF05531.7 EIE88473.1 - 0.0075 16.4 4.1 0.0099 16.1 2.2 1.7 1 1 0 1 1 1 1 Nucleopolyhedrovirus P10 protein DUF4577 PF15145.1 EIE88473.1 - 0.0082 16.0 0.4 0.13 12.1 0.0 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF4577) rve_3 PF13683.1 EIE88473.1 - 0.016 14.7 0.1 0.031 13.8 0.1 1.5 1 0 0 1 1 1 0 Integrase core domain DNA_alkylation PF08713.6 EIE88473.1 - 0.027 13.9 1.9 0.043 13.3 1.3 1.3 1 0 0 1 1 1 0 DNA alkylation repair enzyme DUF3450 PF11932.3 EIE88473.1 - 0.045 13.0 7.2 0.066 12.4 5.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) MRP-L46 PF11788.3 EIE88473.1 - 0.062 13.9 4.2 2 9.1 3.7 2.1 2 1 0 2 2 2 0 39S mitochondrial ribosomal protein L46 Lectin_N PF03954.9 EIE88473.1 - 0.064 12.6 4.8 0.13 11.7 3.3 1.5 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain DUF4239 PF14023.1 EIE88473.1 - 0.073 12.4 3.3 0.15 11.4 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) Atg14 PF10186.4 EIE88473.1 - 0.12 11.3 12.5 0.18 10.7 8.6 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF2110 PF09883.4 EIE88473.1 - 0.13 11.8 1.6 0.19 11.3 1.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2110) SID-1_RNA_chan PF13965.1 EIE88473.1 - 0.25 9.4 4.7 0.3 9.2 3.2 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 AAA_23 PF13476.1 EIE88473.1 - 0.87 9.8 12.2 1.1 9.5 8.4 1.3 1 0 0 1 1 1 0 AAA domain Fib_alpha PF08702.5 EIE88473.1 - 0.98 9.5 11.9 0.15 12.1 5.8 1.5 2 0 0 2 2 1 0 Fibrinogen alpha/beta chain family Med9 PF07544.8 EIE88473.1 - 1 9.1 9.5 2.6 7.8 6.6 1.7 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 DUF4446 PF14584.1 EIE88473.1 - 1.1 9.0 8.8 2.1 8.1 4.2 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF4446) Zip PF02535.17 EIE88473.1 - 1.4 7.8 4.5 3.2 6.6 3.1 1.6 1 1 0 1 1 1 0 ZIP Zinc transporter 7tm_6 PF02949.15 EIE88473.1 - 1.8 7.3 4.5 0.7 8.7 0.1 2.0 1 1 1 2 2 2 0 7tm Odorant receptor DivIC PF04977.10 EIE88473.1 - 2.2 7.8 19.5 0.7 9.4 6.3 3.5 2 1 1 3 3 3 0 Septum formation initiator MscL PF01741.13 EIE88473.1 - 3.6 7.7 6.4 1.1 9.4 0.0 2.6 1 1 0 3 3 3 0 Large-conductance mechanosensitive channel, MscL IncA PF04156.9 EIE88473.1 - 4.8 6.7 21.0 1.1 8.7 12.3 1.6 1 1 0 1 1 1 0 IncA protein DUF904 PF06005.7 EIE88473.1 - 5.4 7.3 20.4 0.49 10.7 8.4 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF904) TMF_DNA_bd PF12329.3 EIE88473.1 - 6.2 6.6 21.0 0.19 11.5 8.0 2.6 2 1 1 3 3 2 0 TATA element modulatory factor 1 DNA binding EIF_2_alpha PF07541.7 EIE88474.1 - 2e-42 143.5 0.2 5.1e-42 142.1 0.0 1.8 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 EIE88474.1 - 9.8e-13 48.0 3.1 2.2e-12 46.9 1.2 2.2 2 0 0 2 2 2 1 S1 RNA binding domain EXOSC1 PF10447.4 EIE88474.1 - 0.039 13.9 0.4 0.13 12.2 0.1 2.1 2 1 0 2 2 2 0 Exosome component EXOSC1/CSL4 APC10 PF03256.11 EIE88475.1 - 0.00017 21.2 0.0 0.00023 20.8 0.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) PQ-loop PF04193.9 EIE88476.1 - 1.4e-19 69.4 10.6 7.5e-19 67.0 3.1 2.5 2 0 0 2 2 2 2 PQ loop repeat DUF793 PF05633.6 EIE88476.1 - 0.0036 16.1 0.0 0.0045 15.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF793) Scs3p PF10261.4 EIE88476.1 - 0.041 12.9 0.4 0.041 12.9 0.3 1.6 2 0 0 2 2 2 0 Inositol phospholipid synthesis and fat-storage-inducing TM DUF2572 PF10833.3 EIE88476.1 - 0.16 11.3 0.6 0.28 10.5 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2572) Gp_dh_C PF02800.15 EIE88477.1 - 3.2e-74 247.6 0.1 5.4e-74 246.8 0.0 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 EIE88477.1 - 4.3e-57 192.3 0.1 6.7e-57 191.7 0.1 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 EIE88477.1 - 0.032 14.1 0.0 0.14 12.0 0.0 2.1 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Poty_coat PF00767.13 EIE88477.1 - 0.096 11.9 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Potyvirus coat protein Pkinase PF00069.20 EIE88478.1 - 8.3e-63 211.9 0.0 1.4e-62 211.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE88478.1 - 3.4e-31 108.2 0.0 3.4e-31 108.2 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE88478.1 - 0.0081 15.1 0.0 0.015 14.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EIE88478.1 - 0.013 14.5 0.0 0.027 13.5 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIE88478.1 - 0.025 14.3 0.1 0.12 12.1 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.17 EIE88478.1 - 0.16 11.2 0.0 0.16 11.2 0.0 2.7 3 1 1 4 4 4 0 RIO1 family YrbL-PhoP_reg PF10707.4 EIE88478.1 - 0.52 9.6 4.1 1.4 8.2 0.0 2.5 3 0 0 3 3 3 0 PhoP regulatory network protein YrbL CENP-B_dimeris PF09026.5 EIE88478.1 - 0.55 10.4 9.2 1.7 8.9 6.4 1.8 1 1 0 1 1 1 0 Centromere protein B dimerisation domain CDC45 PF02724.9 EIE88478.1 - 0.98 7.3 6.8 1.4 6.8 4.7 1.1 1 0 0 1 1 1 0 CDC45-like protein MRI PF15325.1 EIE88479.1 - 0.13 13.2 1.9 0.15 12.9 1.3 1.2 1 0 0 1 1 1 0 Modulator of retrovirus infection AAA PF00004.24 EIE88480.1 - 3.5e-44 150.2 0.0 9.1e-44 148.8 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EIE88480.1 - 2.5e-07 30.7 0.0 5.1e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EIE88480.1 - 3.8e-07 29.8 0.1 2.4e-06 27.3 0.0 2.4 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EIE88480.1 - 2.7e-06 27.4 0.0 1.1e-05 25.4 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EIE88480.1 - 3.4e-06 27.2 0.0 0.00021 21.4 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EIE88480.1 - 5.8e-05 23.9 0.0 0.00016 22.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EIE88480.1 - 9.4e-05 21.5 0.0 0.00016 20.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EIE88480.1 - 0.00012 21.7 0.1 0.00026 20.6 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EIE88480.1 - 0.00036 20.0 0.0 0.00065 19.1 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 EIE88480.1 - 0.00091 18.0 0.0 0.0019 16.9 0.0 1.5 1 1 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 EIE88480.1 - 0.0014 18.5 0.0 0.0029 17.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EIE88480.1 - 0.0015 18.4 0.0 0.0025 17.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EIE88480.1 - 0.0027 16.8 0.0 0.0051 15.9 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_28 PF13521.1 EIE88480.1 - 0.0035 17.3 0.0 0.0059 16.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 EIE88480.1 - 0.004 16.7 0.0 0.011 15.3 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 EIE88480.1 - 0.0058 15.8 0.1 0.015 14.4 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI PhoH PF02562.11 EIE88480.1 - 0.0065 15.7 0.0 0.069 12.3 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein KaiC PF06745.8 EIE88480.1 - 0.0079 15.3 0.0 0.023 13.7 0.0 1.8 2 0 0 2 2 2 1 KaiC AAA_18 PF13238.1 EIE88480.1 - 0.008 16.4 0.0 0.028 14.7 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_25 PF13481.1 EIE88480.1 - 0.014 14.8 0.1 0.088 12.1 0.0 2.0 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.1 EIE88480.1 - 0.016 14.8 0.0 0.034 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EIE88480.1 - 0.017 14.6 0.2 0.086 12.3 0.0 2.2 2 1 0 2 2 2 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 EIE88480.1 - 0.026 14.5 0.1 0.17 11.9 0.0 2.4 2 1 0 2 2 2 0 Sigma-54 interaction domain DUF815 PF05673.8 EIE88480.1 - 0.027 13.3 0.0 0.049 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RNA_helicase PF00910.17 EIE88480.1 - 0.029 14.5 0.0 0.052 13.7 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Parvo_NS1 PF01057.12 EIE88480.1 - 0.041 12.7 0.0 0.077 11.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NACHT PF05729.7 EIE88480.1 - 0.076 12.6 0.0 0.48 10.0 0.0 2.1 1 1 1 2 2 2 0 NACHT domain DUF2072 PF09845.4 EIE88480.1 - 0.12 12.3 0.1 0.31 10.9 0.1 1.7 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) WAK PF08488.6 EIE88481.1 - 0.097 12.9 0.7 0.24 11.7 0.5 1.7 1 0 0 1 1 1 0 Wall-associated kinase Peptidase_M16 PF00675.15 EIE88482.1 - 9.8e-29 100.0 0.3 6e-18 65.0 0.0 4.1 2 2 2 4 4 4 2 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EIE88482.1 - 1.5e-24 86.6 1.6 4.2e-15 55.8 0.0 3.5 3 0 0 3 3 3 2 Peptidase M16 inactive domain DUF3759 PF12585.3 EIE88483.1 - 1.9e-21 75.7 11.5 2.7e-21 75.2 7.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) RicinB_lectin_2 PF14200.1 EIE88483.1 - 8.9e-12 45.3 0.2 0.00023 21.5 0.0 2.8 1 1 2 3 3 3 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 EIE88483.1 - 8.2e-11 42.0 0.0 0.00011 22.2 0.0 2.3 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain DUF4473 PF14747.1 EIE88483.1 - 0.027 14.6 0.4 0.051 13.7 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) Kinesin PF00225.18 EIE88484.1 - 3.1e-81 272.7 3.2 2.3e-80 269.8 0.0 3.2 3 0 0 3 3 3 2 Kinesin motor domain MRP-S23 PF10484.4 EIE88485.1 - 0.012 15.5 2.4 0.013 15.4 1.7 1.0 1 0 0 1 1 1 0 Mitochondrial ribosomal protein S23 Ax_dynein_light PF10211.4 EIE88485.1 - 0.077 12.8 5.4 0.08 12.7 3.8 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain UPF0449 PF15136.1 EIE88485.1 - 0.087 13.0 1.8 0.1 12.8 1.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 LURAP PF14854.1 EIE88485.1 - 0.11 12.2 1.0 0.12 12.0 0.7 1.1 1 0 0 1 1 1 0 Leucine rich adaptor protein MAD PF05557.8 EIE88485.1 - 0.11 10.5 8.5 0.12 10.4 5.9 1.0 1 0 0 1 1 1 0 Mitotic checkpoint protein DUF2681 PF10883.3 EIE88485.1 - 0.29 11.3 2.6 0.36 11.0 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) GrpE PF01025.14 EIE88485.1 - 0.42 10.1 7.6 0.45 10.0 5.3 1.1 1 0 0 1 1 1 0 GrpE DivIC PF04977.10 EIE88485.1 - 0.53 9.8 7.2 0.5 9.8 4.2 1.5 1 1 1 2 2 2 0 Septum formation initiator APG6 PF04111.7 EIE88485.1 - 0.53 9.2 6.0 0.52 9.3 4.1 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 Atg14 PF10186.4 EIE88485.1 - 0.78 8.6 4.8 0.81 8.5 3.3 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4337 PF14235.1 EIE88485.1 - 0.86 9.4 4.9 0.85 9.4 3.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Histone_HNS PF00816.16 EIE88485.1 - 3 8.4 6.7 4.3 7.8 4.6 1.2 1 0 0 1 1 1 0 H-NS histone family Cpn60_TCP1 PF00118.19 EIE88486.1 - 5.7e-153 510.0 0.2 6.5e-153 509.8 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Ribosomal_L3 PF00297.17 EIE88489.1 - 1e-119 398.7 9.4 1.2e-119 398.5 6.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 FadA PF09403.5 EIE88489.1 - 3.5 7.6 6.8 1.8 8.6 2.4 2.0 1 1 1 2 2 2 0 Adhesion protein FadA Pkinase PF00069.20 EIE88491.1 - 6.9e-51 172.8 0.1 9.3e-51 172.4 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE88491.1 - 8.5e-38 129.9 0.0 1.1e-37 129.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE88491.1 - 0.0002 20.4 0.0 0.0017 17.4 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Bystin PF05291.6 EIE88492.1 - 2.7e-137 456.7 0.4 2.7e-137 456.7 0.3 1.4 2 0 0 2 2 2 1 Bystin DUF1649 PF07855.7 EIE88493.1 - 0.037 13.7 0.1 0.071 12.7 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1649) HlyD PF00529.15 EIE88493.1 - 0.058 12.6 0.9 0.094 12.0 0.6 1.3 1 1 0 1 1 1 0 HlyD family secretion protein zf-C2H2 PF00096.21 EIE88495.1 - 7.2e-08 32.3 8.2 9.1e-05 22.5 1.1 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIE88495.1 - 5.3e-07 29.6 1.1 5.3e-07 29.6 0.8 4.2 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EIE88495.1 - 1.1e-06 28.5 4.5 0.00058 19.9 0.6 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EIE88495.1 - 0.032 14.1 0.8 0.23 11.4 0.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger PfkB PF00294.19 EIE88496.1 - 1.4e-07 30.9 0.0 1.7e-07 30.6 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Mt_ATP-synt_B PF05405.9 EIE88497.1 - 7.5e-45 152.3 5.9 1.2e-44 151.6 4.1 1.3 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DivIC PF04977.10 EIE88497.1 - 0.041 13.3 0.4 0.041 13.3 0.3 2.2 1 1 1 2 2 2 0 Septum formation initiator Hepatitis_core PF00906.15 EIE88497.1 - 0.068 12.8 0.2 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 Hepatitis core antigen TFIIE_beta PF02186.10 EIE88498.1 - 1.6e-08 34.4 0.4 4.5e-08 32.9 0.3 1.8 1 0 0 1 1 1 1 TFIIE beta subunit core domain DUF3895 PF13034.1 EIE88498.1 - 0.052 13.0 0.1 0.11 11.9 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3895) AHS2 PF02626.10 EIE88499.1 - 1.5e-06 27.7 3.7 4.3 6.5 0.0 6.8 1 1 8 9 9 9 4 Allophanate hydrolase subunit 2 Stb3 PF10330.4 EIE88499.1 - 6.2e-05 22.6 1.8 12 5.6 0.0 5.9 5 1 2 7 7 7 3 Putative Sin3 binding protein CBS PF00571.23 EIE88499.1 - 0.024 14.3 2.3 2.2e+02 1.7 0.0 6.0 7 0 0 7 7 7 0 CBS domain Pkinase PF00069.20 EIE88500.1 - 1.4e-26 93.2 0.2 1.4e-26 93.2 0.1 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE88500.1 - 6.6e-09 35.2 0.0 6.6e-09 35.2 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Defensin_propep PF00879.13 EIE88501.1 - 0.099 12.6 0.8 0.14 12.0 0.6 1.3 1 0 0 1 1 1 0 Defensin propeptide Homeobox PF00046.24 EIE88502.1 - 3.2e-18 65.0 1.0 5.4e-18 64.3 0.7 1.4 1 0 0 1 1 1 1 Homeobox domain HTH_23 PF13384.1 EIE88502.1 - 0.012 15.2 0.1 0.025 14.2 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain Chitin_synth_2 PF03142.10 EIE88503.1 - 7.7e-244 809.9 1.7 1.1e-243 809.4 1.2 1.2 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 EIE88503.1 - 3.8e-12 46.3 8.7 3.8e-12 46.3 6.0 2.5 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EIE88503.1 - 4.2e-11 43.0 0.0 1.3e-10 41.4 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 EIE88503.1 - 4.4e-06 26.4 0.0 3e-05 23.7 0.0 2.2 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glyco_transf_21 PF13506.1 EIE88503.1 - 0.0037 16.5 0.0 0.41 9.9 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 21 DUF1772 PF08592.6 EIE88504.1 - 5.7e-12 45.5 0.2 8.1e-12 45.0 0.1 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) TMEM237 PF15383.1 EIE88504.1 - 0.13 11.3 0.4 2 7.4 0.0 2.0 2 0 0 2 2 2 0 Transmembrane protein 237 PIF1 PF05970.9 EIE88505.1 - 1.3e-08 34.2 0.0 0.0017 17.3 0.0 2.5 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 EIE88505.1 - 0.0094 15.5 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 EIE88505.1 - 0.017 15.2 0.1 0.11 12.6 0.0 2.1 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain RVT_1 PF00078.22 EIE88506.1 - 5.6e-27 94.4 0.0 8.8e-27 93.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EIE88506.1 - 2.7e-14 52.8 0.1 7.6e-14 51.3 0.0 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EIE88506.1 - 1.3e-05 25.2 0.1 4e-05 23.6 0.0 1.9 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family FlxA PF14282.1 EIE88506.1 - 0.22 11.4 3.6 0.41 10.6 2.5 1.4 1 0 0 1 1 1 0 FlxA-like protein Serglycin PF04360.7 EIE88506.1 - 1.1 9.0 11.3 0.013 15.2 2.3 2.0 2 0 0 2 2 2 0 Serglycin RVT_1 PF00078.22 EIE88507.1 - 0.0015 17.9 0.0 0.0021 17.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EIE88508.1 - 2.9e-15 55.9 0.1 8.1e-15 54.4 0.0 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EIE88508.1 - 4.4e-06 26.7 0.1 1.5e-05 25.1 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Serglycin PF04360.7 EIE88508.1 - 0.027 14.1 4.4 0.057 13.1 2.7 1.8 2 0 0 2 2 2 0 Serglycin FlxA PF14282.1 EIE88508.1 - 0.23 11.4 2.7 0.44 10.5 1.8 1.4 1 0 0 1 1 1 0 FlxA-like protein DUF3408 PF11888.3 EIE88509.1 - 0.003 17.5 1.1 0.014 15.3 0.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3408) Sin3_corepress PF08295.7 EIE88509.1 - 0.058 13.1 0.6 38 4.1 0.0 3.4 3 0 0 3 3 3 0 Sin3 family co-repressor Fmp27_WPPW PF10359.4 EIE88509.1 - 0.062 11.7 0.8 0.098 11.0 0.6 1.3 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF4407 PF14362.1 EIE88509.1 - 0.78 8.6 5.1 1.5 7.7 3.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RVT_1 PF00078.22 EIE88510.1 - 4.7e-29 101.2 0.0 1.5e-28 99.6 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EIE88510.1 - 1.3e-14 53.8 0.0 3.1e-14 52.5 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RVT_1 PF00078.22 EIE88511.1 - 1.7e-15 56.9 0.0 3.3e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EIE88511.1 - 1.3e-14 53.7 0.1 4.4e-14 52.0 0.0 2.0 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EIE88511.1 - 1.1e-05 25.5 0.0 3.8e-05 23.7 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SYCE1 PF15233.1 EIE88511.1 - 0.006 16.5 0.5 0.012 15.5 0.3 1.4 1 0 0 1 1 1 1 Synaptonemal complex central element protein 1 TBPIP PF07106.8 EIE88511.1 - 0.29 10.6 0.0 0.52 9.8 0.0 1.3 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF972 PF06156.8 EIE88511.1 - 0.29 11.4 0.1 0.53 10.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) RVT_1 PF00078.22 EIE88513.1 - 4.7e-29 101.2 0.0 1.5e-28 99.6 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EIE88513.1 - 1.7e-15 56.6 0.0 4.8e-15 55.2 0.0 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RVT_1 PF00078.22 EIE88514.1 - 1.3e-19 70.4 0.0 2.3e-19 69.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EIE88514.1 - 1.2e-14 53.9 0.0 3.2e-14 52.5 0.0 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EIE88514.1 - 9.8e-06 25.6 1.1 1.5e-05 25.0 0.0 1.9 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family SYCE1 PF15233.1 EIE88514.1 - 0.006 16.5 0.5 0.013 15.4 0.3 1.5 1 0 0 1 1 1 1 Synaptonemal complex central element protein 1 DUF972 PF06156.8 EIE88514.1 - 0.19 12.0 0.3 0.56 10.5 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DUF177 PF02620.12 EIE88514.1 - 0.21 11.6 0.0 0.39 10.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized ACR, COG1399 TBPIP PF07106.8 EIE88514.1 - 0.26 10.8 0.0 0.47 9.9 0.0 1.3 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DNA_pol3_delta2 PF13177.1 EIE88515.1 - 0.038 13.6 0.1 0.051 13.2 0.1 1.2 1 0 0 1 1 1 0 DNA polymerase III, delta subunit RVT_1 PF00078.22 EIE88517.1 - 1.3e-32 112.8 0.2 3e-32 111.7 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.1 EIE88517.1 - 6.8e-06 26.3 0.7 2.4e-05 24.5 0.5 2.0 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Aa_trans PF01490.13 EIE88518.1 - 2.5e-77 260.0 39.4 2.9e-77 259.8 27.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Spore_permease PF03845.8 EIE88518.1 - 0.00013 20.7 25.3 0.00028 19.6 17.5 1.6 1 0 0 1 1 1 1 Spore germination protein DUF3808 PF10300.4 EIE88519.1 - 1.4e-10 40.3 0.1 1.9e-10 39.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) DUF1789 PF08748.6 EIE88519.1 - 0.1 12.7 0.1 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1789) RNA_pol_Rpb2_6 PF00562.23 EIE88521.1 - 2e-128 428.4 0.0 3.2e-128 427.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EIE88521.1 - 4e-67 225.0 0.0 6e-67 224.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EIE88521.1 - 6.1e-47 159.5 0.0 5e-46 156.5 0.0 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EIE88521.1 - 8.7e-32 109.2 0.1 3e-31 107.4 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 EIE88521.1 - 2e-26 91.5 0.1 4.4e-26 90.4 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.12 EIE88521.1 - 4.6e-23 80.9 0.1 1e-22 79.7 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_3 PF04565.11 EIE88521.1 - 9.1e-23 79.7 0.0 1.9e-22 78.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 Beta_helix PF13229.1 EIE88522.1 - 0.0001 22.1 6.7 0.039 13.7 4.7 2.6 1 1 0 1 1 1 1 Right handed beta helix region DUF4174 PF13778.1 EIE88522.1 - 0.00083 19.4 3.5 3.6 7.7 0.0 4.1 3 2 1 4 4 4 2 Domain of unknown function (DUF4174) Multi_ubiq PF14452.1 EIE88522.1 - 0.068 13.1 4.9 19 5.3 0.0 4.7 4 2 0 4 4 4 0 Multiubiquitin Borrelia_lipo_2 PF06238.6 EIE88522.1 - 0.15 12.1 16.4 3.2 7.8 0.0 5.4 6 0 0 6 6 6 0 Borrelia burgdorferi BBR25 lipoprotein S4_2 PF13275.1 EIE88522.1 - 4.3 7.0 15.3 0.5 9.9 0.3 4.7 3 1 2 6 6 6 0 S4 domain HAD_2 PF13419.1 EIE88523.1 - 9e-22 78.1 0.0 1.6e-21 77.3 0.0 1.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EIE88523.1 - 0.011 15.4 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like Hydrolase PF00702.21 EIE88523.1 - 0.013 15.9 0.1 0.069 13.5 0.1 1.9 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase MBOAT PF03062.14 EIE88524.1 - 1.2e-28 100.1 4.7 2.8e-28 98.9 3.2 1.6 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family EST1_DNA_bind PF10373.4 EIE88524.1 - 0.0075 15.5 0.6 0.11 11.6 0.0 2.4 3 0 0 3 3 3 1 Est1 DNA/RNA binding domain MMR_HSR1 PF01926.18 EIE88526.1 - 8.7e-13 48.2 0.0 1.5e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EIE88526.1 - 2.2e-05 23.7 0.0 3.3e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 EIE88526.1 - 0.00049 19.4 0.0 0.0011 18.2 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EIE88526.1 - 0.0014 18.4 0.9 0.0073 16.1 0.1 2.3 2 1 1 3 3 3 1 Dynamin family Miro PF08477.8 EIE88526.1 - 0.0079 16.6 0.0 0.016 15.6 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein AIG1 PF04548.11 EIE88526.1 - 0.014 14.4 0.0 0.025 13.6 0.0 1.3 1 0 0 1 1 1 0 AIG1 family MobB PF03205.9 EIE88526.1 - 0.058 13.0 0.3 0.31 10.7 0.1 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NPV_P10 PF05531.7 EIE88527.1 - 0.02 15.0 5.5 0.86 9.8 0.1 3.3 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF4320 PF14208.1 EIE88527.1 - 0.096 12.6 0.9 5.9 6.8 0.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4320) MbeD_MobD PF04899.7 EIE88527.1 - 0.16 11.9 5.5 0.18 11.7 1.4 3.0 2 2 0 2 2 2 0 MbeD/MobD like MerR-DNA-bind PF09278.6 EIE88527.1 - 2.7 8.4 11.7 3.9 7.9 0.1 4.1 4 1 1 5 5 5 0 MerR, DNA binding ATG16 PF08614.6 EIE88527.1 - 8.7 6.1 29.0 0.28 11.0 5.5 3.3 3 1 1 4 4 4 0 Autophagy protein 16 (ATG16) SEP PF08059.8 EIE88528.1 - 1.6e-26 92.4 0.1 3.6e-26 91.2 0.0 1.7 2 0 0 2 2 2 1 SEP domain UBA_4 PF14555.1 EIE88528.1 - 1.2e-08 34.3 0.1 2.1e-08 33.5 0.1 1.5 1 0 0 1 1 1 1 UBA-like domain Turandot PF07240.6 EIE88528.1 - 0.022 14.2 0.0 0.064 12.7 0.0 1.7 1 0 0 1 1 1 0 Stress-inducible humoral factor Turandot zf-C2H2_4 PF13894.1 EIE88529.1 - 2.3e-12 46.2 18.6 0.00034 20.7 1.0 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EIE88529.1 - 1.7e-10 40.5 20.4 7.6e-05 22.8 2.0 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIE88529.1 - 2.3e-08 33.9 17.7 0.00024 21.2 0.9 3.9 4 0 0 4 4 4 3 Zinc-finger double domain zf-Di19 PF05605.7 EIE88529.1 - 0.00036 20.5 8.9 0.0045 17.0 3.1 2.3 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 EIE88529.1 - 0.0028 17.7 12.1 0.18 12.0 0.1 3.4 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 EIE88529.1 - 0.0051 16.9 1.9 0.0051 16.9 1.3 3.9 3 1 0 3 3 3 1 C2H2-type zinc-finger domain DUF629 PF04780.7 EIE88529.1 - 0.044 12.2 7.4 0.079 11.4 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF629) zf-C2H2_2 PF12756.2 EIE88529.1 - 0.064 13.3 10.7 2.5 8.2 0.1 3.1 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) Rpr2 PF04032.11 EIE88529.1 - 0.13 12.1 4.5 0.11 12.3 1.3 2.0 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zinc-ribbons_6 PF07191.7 EIE88529.1 - 0.38 10.5 3.6 4.6 7.1 0.9 2.3 2 0 0 2 2 2 0 zinc-ribbons Elf1 PF05129.8 EIE88529.1 - 0.47 10.1 13.6 0.42 10.3 5.1 2.4 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like DZR PF12773.2 EIE88529.1 - 6 6.7 7.1 43 4.0 0.2 2.3 1 1 1 2 2 2 0 Double zinc ribbon C1_4 PF07975.7 EIE88529.1 - 9.5 6.3 10.2 13 5.8 0.2 2.8 2 1 1 3 3 3 0 TFIIH C1-like domain Radical_SAM PF04055.16 EIE88531.1 - 1.9e-16 60.6 0.0 5.1e-16 59.2 0.0 1.7 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 EIE88531.1 - 2.2e-11 43.6 0.0 6e-11 42.2 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EIE88531.1 - 0.15 11.8 0.0 0.37 10.5 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein HAUS-augmin3 PF14932.1 EIE88532.1 - 0.0036 16.5 9.6 0.034 13.3 0.5 2.1 1 1 1 2 2 2 2 HAUS augmin-like complex subunit 3 Occludin_ELL PF07303.8 EIE88532.1 - 0.011 16.4 7.2 1.6 9.5 2.1 2.6 1 1 1 2 2 2 0 Occludin homology domain Phage_GP20 PF06810.6 EIE88532.1 - 0.038 13.4 6.8 1.4 8.3 2.4 2.3 1 1 1 2 2 2 0 Phage minor structural protein GP20 Fib_alpha PF08702.5 EIE88532.1 - 0.13 12.4 6.8 0.12 12.4 1.0 2.7 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family GAS PF13851.1 EIE88532.1 - 0.17 11.0 11.5 0.26 10.4 5.0 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding FTA4 PF13093.1 EIE88532.1 - 0.2 11.0 7.3 0.49 9.7 4.5 2.1 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 V_ATPase_I PF01496.14 EIE88532.1 - 0.35 8.6 4.4 0.4 8.4 3.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CENP-Q PF13094.1 EIE88532.1 - 0.78 9.7 10.6 0.14 12.1 3.7 2.3 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF4446 PF14584.1 EIE88532.1 - 0.85 9.4 4.7 0.52 10.1 1.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) DUF4407 PF14362.1 EIE88532.1 - 1 8.2 5.8 1.3 7.9 4.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2951 PF11166.3 EIE88532.1 - 1.1 9.1 5.5 0.52 10.1 1.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2951) YlbD_coat PF14071.1 EIE88532.1 - 1.4 8.9 6.3 0.93 9.5 0.9 2.8 1 1 2 3 3 3 0 Putative coat protein Ly49 PF08391.5 EIE88532.1 - 2.1 8.4 6.2 0.15 12.2 0.2 2.1 3 0 0 3 3 2 0 Ly49-like protein, N-terminal region SlyX PF04102.7 EIE88532.1 - 2.8 8.3 5.6 2.1 8.7 0.5 2.8 3 0 0 3 3 3 0 SlyX DUF972 PF06156.8 EIE88532.1 - 6 7.2 9.3 10 6.5 2.2 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Kinesin PF00225.18 EIE88533.1 - 1e-97 326.8 0.1 5.2e-97 324.5 0.0 2.2 2 0 0 2 2 2 1 Kinesin motor domain DUF3694 PF12473.3 EIE88533.1 - 2.5e-22 79.0 0.5 7.5e-22 77.5 0.4 1.9 1 0 0 1 1 1 1 Kinesin protein RBD-FIP PF09457.5 EIE88535.1 - 0.033 13.9 0.3 0.069 12.9 0.0 1.6 2 0 0 2 2 2 0 FIP domain Med8 PF10232.4 EIE88536.1 - 7.1e-11 42.0 9.4 1.1e-10 41.4 6.5 1.4 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 TMCO5 PF14992.1 EIE88537.1 - 0.0037 16.4 10.2 0.0037 16.4 7.1 3.8 1 1 3 4 4 4 1 TMCO5 family DUF904 PF06005.7 EIE88537.1 - 0.012 15.8 3.3 0.012 15.8 2.3 6.7 3 1 1 4 4 4 0 Protein of unknown function (DUF904) bZIP_1 PF00170.16 EIE88537.1 - 0.016 15.1 1.2 0.016 15.1 0.8 7.7 6 2 2 8 8 8 0 bZIP transcription factor C1_4 PF07975.7 EIE88537.1 - 1.1 9.2 4.4 2.8 8.0 0.9 2.7 2 0 0 2 2 2 0 TFIIH C1-like domain DUF763 PF05559.6 EIE88537.1 - 7 5.5 15.4 1.7 7.5 2.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF763) Metallophos PF00149.23 EIE88538.1 - 4.1e-34 117.7 0.1 5.6e-34 117.3 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase eIF-1a PF01176.14 EIE88541.1 - 7.1e-28 95.8 0.4 9.9e-28 95.3 0.3 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Myb_DNA-bind_6 PF13921.1 EIE88541.1 - 0.069 13.2 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain DUF1212 PF06738.7 EIE88542.1 - 4.3e-39 134.0 8.6 2.9e-37 127.9 0.7 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 EIE88542.1 - 3.7e-19 68.9 6.6 3.7e-19 68.9 4.6 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3815) RNA_pol_Rpb2_1 PF04563.10 EIE88544.1 - 0.035 13.0 0.1 0.045 12.6 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase beta subunit AMP-binding PF00501.23 EIE88545.1 - 1.7e-23 82.7 0.0 1.9e-23 82.5 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EIE88546.1 - 2.9e-11 42.7 0.0 9e-11 41.1 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein Nup54 PF13874.1 EIE88547.1 - 2.2e-35 121.3 7.5 2.2e-35 121.3 5.2 1.9 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 NPV_P10 PF05531.7 EIE88547.1 - 0.54 10.5 2.8 33 4.8 0.4 3.0 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Retrotrans_gag PF03732.12 EIE88547.1 - 1.6 8.8 5.1 2.4 8.3 0.6 2.6 1 1 2 3 3 3 0 Retrotransposon gag protein Nucleoporin_FG PF13634.1 EIE88547.1 - 1.8 8.8 40.4 4 7.7 28.0 1.5 1 0 0 1 1 1 0 Nucleoporin FG repeat region IBN_N PF03810.14 EIE88549.1 - 3.1e-16 59.0 0.1 3.2e-15 55.7 0.0 2.6 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.7 EIE88549.1 - 0.0017 18.2 0.8 0.0041 17.0 0.2 1.9 2 1 0 2 2 2 1 Exportin 1-like protein HEAT_2 PF13646.1 EIE88550.1 - 0.0023 18.1 0.1 0.0096 16.1 0.1 2.2 1 1 0 1 1 1 1 HEAT repeats HEAT_EZ PF13513.1 EIE88550.1 - 0.034 14.6 0.2 0.52 10.8 0.0 3.0 2 0 0 2 2 2 0 HEAT-like repeat NUDIX PF00293.23 EIE88551.1 - 9.7e-15 54.4 0.0 1.6e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Pacs-1 PF10254.4 EIE88551.1 - 0.066 11.8 2.1 0.083 11.5 1.5 1.2 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein RF-1 PF00472.15 EIE88552.1 - 6.5e-41 138.7 5.1 1.2e-40 137.8 3.5 1.5 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 EIE88552.1 - 4.3e-26 90.8 0.5 1.4e-25 89.2 0.3 1.9 1 0 0 1 1 1 1 PCRF domain MIR PF02815.14 EIE88552.1 - 0.013 15.0 0.6 0.035 13.6 0.1 1.9 2 0 0 2 2 2 0 MIR domain CorA PF01544.13 EIE88552.1 - 3.3 6.6 7.8 0.44 9.5 2.5 1.6 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein GCR1_C PF12550.3 EIE88554.1 - 1e-23 82.9 0.2 3.9e-23 81.1 0.1 2.1 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes DDE_3 PF13358.1 EIE88555.1 - 1.3e-20 73.5 0.1 2.2e-20 72.8 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE88555.1 - 1.5e-15 57.0 2.5 3.8e-15 55.6 0.2 2.6 3 0 0 3 3 3 1 Transposase Ku_PK_bind PF08785.6 EIE88555.1 - 0.0037 17.1 0.0 0.0073 16.1 0.0 1.5 1 0 0 1 1 1 1 Ku C terminal domain like rve PF00665.21 EIE88555.1 - 0.011 15.8 0.0 0.026 14.6 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain HTH_21 PF13276.1 EIE88555.1 - 0.049 13.6 0.1 0.15 12.0 0.1 1.9 1 0 0 1 1 1 0 HTH-like domain TC1 PF15063.1 EIE88555.1 - 0.078 12.5 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 Thyroid cancer protein 1 DDE_3 PF13358.1 EIE88556.1 - 3.6e-08 33.2 0.1 4.7e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EIE88557.1 - 2.5e-18 66.2 0.1 6e-18 64.9 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE88557.1 - 4.2e-09 36.3 0.7 1.8e-08 34.3 0.7 2.0 2 1 0 2 2 2 1 Transposase Pox_RNA_Pol_19 PF05320.7 EIE88558.1 - 8 6.1 8.0 8.1 6.1 5.5 1.1 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit DDE_3 PF13358.1 EIE88559.1 - 9.8e-21 74.0 0.0 1.8e-20 73.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE88559.1 - 8.9e-05 22.4 1.0 0.00014 21.8 0.1 1.8 2 0 0 2 2 2 1 Transposase Sigma70_r1_2 PF00140.15 EIE88559.1 - 0.0051 16.4 0.1 0.011 15.4 0.1 1.5 1 0 0 1 1 1 1 Sigma-70 factor, region 1.2 DDE_3 PF13358.1 EIE88560.1 - 2.5e-20 72.7 0.2 4.4e-20 71.9 0.2 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE88560.1 - 2.7e-18 65.7 3.2 3.7e-18 65.3 0.9 2.3 3 0 0 3 3 3 1 Transposase HTH_29 PF13551.1 EIE88560.1 - 4.8e-08 33.1 0.9 1.4e-07 31.6 0.6 1.8 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EIE88560.1 - 0.00039 19.9 0.7 0.0069 16.0 0.0 2.9 3 0 0 3 3 3 1 Homeodomain-like domain HTH_32 PF13565.1 EIE88560.1 - 0.0014 19.4 5.4 0.0025 18.5 0.2 3.7 4 1 1 5 5 4 1 Homeodomain-like domain rve PF00665.21 EIE88560.1 - 0.0049 16.9 0.0 0.016 15.3 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Ku_PK_bind PF08785.6 EIE88560.1 - 0.0072 16.2 0.1 0.02 14.7 0.0 1.8 2 0 0 2 2 2 1 Ku C terminal domain like HTH_28 PF13518.1 EIE88560.1 - 0.015 15.2 0.0 0.061 13.3 0.0 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_40 PF14493.1 EIE88560.1 - 0.026 14.7 0.5 0.95 9.7 0.0 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain Trp_repressor PF01371.14 EIE88560.1 - 0.072 13.0 0.0 0.54 10.2 0.0 2.2 2 0 0 2 2 2 0 Trp repressor protein Peptidase_C34 PF05413.6 EIE88560.1 - 0.083 12.9 0.0 3.5 7.7 0.0 2.4 2 0 0 2 2 2 0 Putative closterovirus papain-like endopeptidase HTH_12 PF08461.5 EIE88560.1 - 0.22 11.2 0.2 0.22 11.2 0.1 2.5 4 0 0 4 4 4 0 Ribonuclease R winged-helix domain HTH_17 PF12728.2 EIE88560.1 - 0.25 11.6 1.8 0.94 9.7 0.1 2.6 3 0 0 3 3 3 0 Helix-turn-helix domain Transposase_21 PF02992.9 EIE88562.1 - 1.9e-21 76.1 0.3 6.5e-21 74.4 0.0 1.9 2 0 0 2 2 2 1 Transposase family tnp2 DUF1258 PF06869.7 EIE88562.1 - 0.0054 15.8 0.0 0.011 14.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) HTH_Tnp_Tc3_2 PF01498.13 EIE88564.1 - 0.00019 21.4 0.3 0.00024 21.1 0.2 1.2 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.1 EIE88565.1 - 3.4e-12 46.3 0.8 7.7e-12 45.1 0.1 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease NUDIX_4 PF14815.1 EIE88565.1 - 0.053 12.9 0.4 0.068 12.5 0.3 1.2 1 0 0 1 1 1 0 NUDIX domain HTH_Tnp_Tc3_2 PF01498.13 EIE88566.1 - 5.4e-17 61.6 0.6 5.4e-17 61.6 0.4 1.6 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 EIE88566.1 - 3.1e-06 27.2 0.2 9.6e-06 25.7 0.2 1.8 1 1 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EIE88566.1 - 0.0001 21.8 0.2 0.0026 17.3 0.0 2.9 4 0 0 4 4 4 1 Homeodomain-like domain HTH_32 PF13565.1 EIE88566.1 - 0.001 19.7 2.3 0.0056 17.4 0.1 2.9 3 1 0 3 3 3 1 Homeodomain-like domain HTH_21 PF13276.1 EIE88566.1 - 0.087 12.8 0.2 0.46 10.5 0.0 2.2 2 0 0 2 2 2 0 HTH-like domain Transposase_21 PF02992.9 EIE88568.1 - 1.2e-08 34.3 0.0 3.1e-07 29.7 0.0 2.3 1 1 1 2 2 2 1 Transposase family tnp2 DUF3713 PF12506.3 EIE88568.1 - 0.00021 21.3 0.5 0.00055 19.9 0.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3713) TGS PF02824.16 EIE88568.1 - 0.023 14.5 0.0 5.3 6.9 0.0 2.8 2 1 0 2 2 2 0 TGS domain HTH_Tnp_Tc3_2 PF01498.13 EIE88570.1 - 4e-08 33.2 1.7 9.2e-08 32.0 0.7 1.9 1 1 1 2 2 2 1 Transposase HTH_Tnp_Tc3_2 PF01498.13 EIE88572.1 - 1.7e-08 34.4 3.3 4.7e-08 32.9 0.4 2.2 1 1 1 2 2 2 1 Transposase HTH_Tnp_Tc3_2 PF01498.13 EIE88573.1 - 6e-09 35.8 1.4 1.3e-08 34.7 0.7 1.8 1 1 1 2 2 2 1 Transposase DDE_3 PF13358.1 EIE88573.1 - 0.0044 16.7 0.0 0.011 15.4 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease Transposase_21 PF02992.9 EIE88574.1 - 1.2e-21 76.8 0.0 1.9e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 Transposase family tnp2 DUF1258 PF06869.7 EIE88574.1 - 0.0033 16.5 0.0 0.0053 15.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) Evr1_Alr PF04777.8 EIE88574.1 - 0.11 12.4 0.2 1.5 8.7 0.1 2.3 2 0 0 2 2 2 0 Erv1 / Alr family DDE_3 PF13358.1 EIE88575.1 - 3.8e-15 55.8 0.1 7.1e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE88575.1 - 8.7e-14 51.3 0.3 2.5e-13 49.8 0.2 1.9 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.1 EIE88575.1 - 2.3e-06 27.6 0.5 4.7e-06 26.7 0.3 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EIE88575.1 - 0.00078 19.0 0.2 0.0033 17.0 0.0 2.1 2 0 0 2 2 2 1 Homeodomain-like domain HTH_7 PF02796.10 EIE88575.1 - 0.0016 18.2 0.3 0.081 12.7 0.0 2.7 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase rve PF00665.21 EIE88575.1 - 0.081 13.0 0.0 0.21 11.7 0.0 1.9 1 1 0 1 1 1 0 Integrase core domain HTH_Tnp_Tc3_2 PF01498.13 EIE88576.1 - 2.5e-16 59.4 0.2 2.7e-16 59.3 0.2 1.0 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.1 EIE88576.1 - 0.0063 16.6 0.1 0.011 15.8 0.0 1.4 2 0 0 2 2 2 1 Winged helix-turn helix HTH_21 PF13276.1 EIE88576.1 - 0.03 14.3 0.0 0.05 13.6 0.0 1.4 1 0 0 1 1 1 0 HTH-like domain HTH_32 PF13565.1 EIE88576.1 - 0.032 15.0 0.1 0.36 11.6 0.0 2.0 2 0 0 2 2 2 0 Homeodomain-like domain HTH_12 PF08461.5 EIE88576.1 - 0.033 13.9 0.2 0.22 11.2 0.0 1.9 1 1 1 2 2 2 0 Ribonuclease R winged-helix domain DDE_Tnp_ISAZ013 PF07592.6 EIE88576.1 - 0.073 11.7 0.0 0.074 11.7 0.0 1.1 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain Ribonucleas_3_2 PF11469.3 EIE88576.1 - 0.088 13.0 0.0 0.096 12.8 0.0 1.1 1 0 0 1 1 1 0 Ribonuclease III IncA PF04156.9 EIE88579.1 - 1.5 8.4 15.2 1.9 8.0 10.5 1.2 1 0 0 1 1 1 0 IncA protein DDE_Tnp_IS1595 PF12762.2 EIE88580.1 - 1.5e-14 54.0 0.0 6e-09 35.9 0.0 2.8 2 1 0 2 2 2 2 ISXO2-like transposase domain DDE_Tnp_IS1595 PF12762.2 EIE88581.1 - 3.5e-18 65.8 2.4 2.2e-12 47.0 0.1 3.1 2 1 0 2 2 2 2 ISXO2-like transposase domain DDE_3 PF13358.1 EIE88582.1 - 0.0023 17.6 0.1 0.0059 16.3 0.1 1.8 1 1 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EIE88584.1 - 1.5e-12 47.4 2.1 2.1e-12 46.9 0.5 1.8 2 1 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE88584.1 - 1e-08 35.0 0.2 1e-08 35.0 0.1 2.4 1 1 1 2 2 2 1 Transposase rve PF00665.21 EIE88584.1 - 0.043 13.9 0.0 0.079 13.0 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain Imm35 PF15581.1 EIE88584.1 - 0.091 12.7 0.5 1.9 8.5 0.0 2.5 2 0 0 2 2 2 0 Immunity protein 35 HTH_29 PF13551.1 EIE88584.1 - 0.14 12.3 2.7 0.16 12.1 0.8 2.0 2 1 0 2 2 2 0 Winged helix-turn helix HTH_32 PF13565.1 EIE88584.1 - 0.18 12.6 0.4 0.18 12.6 0.3 2.6 3 0 0 3 3 3 0 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.1 EIE88584.1 - 0.8 8.9 3.1 0.81 8.9 0.1 2.5 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 DUF1033 PF06279.6 EIE88584.1 - 0.82 9.4 5.9 0.3 10.8 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1033) NFRKB_winged PF14465.1 EIE88584.1 - 1.4 8.7 6.0 4.3 7.2 0.7 2.9 2 2 1 3 3 3 0 NFRKB Winged Helix-like DDE_3 PF13358.1 EIE88585.1 - 2.8e-08 33.6 0.1 2.2e-07 30.7 0.0 2.3 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_29 PF13551.1 EIE88585.1 - 2.1e-05 24.6 0.2 0.00096 19.2 0.0 2.6 1 1 1 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.1 EIE88585.1 - 0.002 17.6 0.0 0.0053 16.3 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.1 EIE88585.1 - 0.018 15.7 1.6 7.4 7.4 0.1 3.1 3 1 1 4 4 4 0 Homeodomain-like domain FliT PF05400.8 EIE88585.1 - 0.12 12.7 0.2 0.12 12.7 0.2 2.9 4 0 0 4 4 4 0 Flagellar protein FliT zf-RVT PF13966.1 EIE88586.1 - 0.041 14.1 3.3 0.087 13.1 2.3 1.6 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase RVT_1 PF00078.22 EIE88587.1 - 3.5e-05 23.2 2.5 0.00025 20.4 0.4 2.4 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) AP-5_subunit_s1 PF15001.1 EIE88587.1 - 0.064 13.2 0.1 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 RVT_1 PF00078.22 EIE88588.1 - 1.5e-24 86.5 0.5 3e-24 85.5 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_3 PF13358.1 EIE88588.1 - 9e-18 64.4 0.0 2e-17 63.3 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE88588.1 - 1.7e-08 34.3 1.3 5e-08 32.8 0.9 1.9 1 0 0 1 1 1 1 Transposase Exo_endo_phos PF03372.18 EIE88589.1 - 5e-13 49.5 0.4 9.3e-13 48.6 0.3 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EIE88589.1 - 9.4e-06 25.2 0.0 2.6e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase zf-CCHC PF00098.18 EIE88589.1 - 0.00046 19.9 12.0 0.0011 18.7 3.1 2.7 2 0 0 2 2 2 2 Zinc knuckle rve PF00665.21 EIE88590.1 - 7.1e-18 64.8 0.0 2.1e-17 63.3 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE88590.1 - 5.7e-15 55.2 0.2 1.3e-14 54.0 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.5 EIE88590.1 - 0.00057 19.2 0.4 0.00057 19.2 0.2 2.1 2 0 0 2 2 2 1 His(2)-Cys(2) zinc finger Retrotrans_gag PF03732.12 EIE88591.1 - 1.5e-06 28.1 0.1 5.4e-06 26.3 0.0 2.1 2 0 0 2 2 2 1 Retrotransposon gag protein HAD PF12710.2 EIE88592.1 - 0.00011 22.4 0.4 0.18 11.9 0.1 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase DDE_3 PF13358.1 EIE88593.1 - 2.8e-20 72.5 0.4 5.7e-20 71.5 0.1 1.6 1 1 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_ISAZ013 PF07592.6 EIE88593.1 - 0.00074 18.3 0.5 0.015 14.0 0.0 2.0 2 0 0 2 2 2 2 Rhodopirellula transposase DDE domain YdjO PF14169.1 EIE88593.1 - 0.12 11.8 0.2 0.22 10.9 0.0 1.6 2 0 0 2 2 2 0 Cold-inducible protein YdjO MULE PF10551.4 EIE88594.1 - 1.3e-07 31.6 0.0 3.2e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 EIE88594.1 - 2.6e-05 22.9 0.5 3.2e-05 22.6 0.3 1.2 1 0 0 1 1 1 1 Transposase, Mutator family DDE_Tnp_IS240 PF13610.1 EIE88594.1 - 0.021 14.7 0.0 0.76 9.7 0.0 2.2 2 0 0 2 2 2 0 DDE domain Porphobil_deam PF01379.15 EIE88594.1 - 0.11 11.3 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Porphobilinogen deaminase, dipyromethane cofactor binding domain DUF3446 PF11928.3 EIE88595.1 - 0.74 10.0 9.2 2 8.6 1.5 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) DUF2783 PF10932.3 EIE88599.1 - 0.13 11.7 0.1 0.27 10.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2783) RPN7 PF10602.4 EIE88601.1 - 0.079 12.3 1.3 6.6 6.0 0.0 2.1 1 1 1 2 2 2 0 26S proteasome subunit RPN7 DDE_3 PF13358.1 EIE88603.1 - 6.1e-22 77.9 0.0 1.3e-21 76.8 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_1 PF03184.14 EIE88603.1 - 1.4e-07 30.8 0.1 2.4e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_ISAZ013 PF07592.6 EIE88603.1 - 0.0037 16.0 0.0 0.0056 15.4 0.0 1.2 1 0 0 1 1 1 1 Rhodopirellula transposase DDE domain rve PF00665.21 EIE88603.1 - 0.0037 17.3 0.0 0.0069 16.4 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain DUF605 PF04652.11 EIE88603.1 - 0.14 11.4 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Vta1 like DUF806 PF05657.6 EIE88604.1 - 0.084 12.9 0.2 0.086 12.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF806) Heme_oxygenase PF01126.15 EIE88605.1 - 2.5e-56 190.4 0.9 3.4e-56 190.0 0.6 1.2 1 0 0 1 1 1 1 Heme oxygenase HLH PF00010.21 EIE88606.1 - 2.8e-15 55.7 0.4 7.4e-15 54.3 0.3 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain CBP4 PF07960.6 EIE88606.1 - 0.079 12.5 1.1 0.15 11.7 0.4 1.7 2 0 0 2 2 2 0 CBP4 TPR_11 PF13414.1 EIE88607.1 - 3.3e-16 58.6 15.5 2.5e-05 23.8 0.0 6.1 6 0 0 6 6 6 4 TPR repeat TPR_19 PF14559.1 EIE88607.1 - 2e-13 50.4 12.8 0.0072 16.6 0.1 6.3 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 EIE88607.1 - 8.6e-13 48.5 0.1 0.015 15.9 0.0 5.0 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 EIE88607.1 - 9.2e-13 47.3 4.9 0.06 13.5 0.0 7.6 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_1 PF00515.23 EIE88607.1 - 1.7e-12 46.3 21.1 0.02 14.5 0.0 8.1 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_14 PF13428.1 EIE88607.1 - 4.5e-10 39.2 3.9 0.65 10.8 0.0 6.4 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.12 EIE88607.1 - 7.4e-10 37.9 16.9 0.25 11.3 0.0 8.1 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_12 PF13424.1 EIE88607.1 - 3.5e-06 26.8 23.1 0.23 11.3 0.7 7.6 4 2 3 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.1 EIE88607.1 - 2.1e-05 23.9 19.1 0.49 10.3 0.0 6.9 8 0 0 8 8 8 3 Tetratricopeptide repeat Apc3 PF12895.2 EIE88607.1 - 4.1e-05 23.6 12.6 1.1 9.4 0.0 5.0 5 1 0 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EIE88607.1 - 0.00027 20.7 2.5 0.13 12.1 0.0 4.1 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 EIE88607.1 - 0.056 13.2 3.9 31 4.6 0.0 5.5 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 EIE88607.1 - 6.3 7.4 13.1 93 3.8 0.0 6.2 6 0 0 6 6 5 0 Tetratricopeptide repeat Glycos_transf_1 PF00534.15 EIE88608.1 - 1.6e-24 86.2 0.0 2.7e-24 85.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 EIE88608.1 - 9.3e-13 48.2 1.3 2.8e-12 46.6 0.9 1.8 1 1 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_1_4 PF13692.1 EIE88608.1 - 5.9e-09 36.1 0.0 1.8e-08 34.6 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EIE88608.1 - 0.029 14.5 0.0 0.073 13.2 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain DUF3425 PF11905.3 EIE88609.1 - 6.7e-16 58.4 6.6 7.5e-14 51.7 4.6 2.5 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 EIE88609.1 - 2.5e-10 40.1 6.2 2.5e-10 40.1 4.3 2.0 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EIE88609.1 - 0.0037 17.0 11.4 0.0088 15.8 7.9 1.6 1 0 0 1 1 1 1 Basic region leucine zipper FAD_binding_2 PF00890.19 EIE88610.1 - 6.6e-125 417.2 5.2 9.2e-125 416.7 3.6 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 EIE88610.1 - 4.2e-48 162.4 0.4 7e-48 161.7 0.3 1.4 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 EIE88610.1 - 1.1e-07 31.9 0.0 0.0012 18.7 0.1 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EIE88610.1 - 4.1e-06 26.0 0.2 0.0079 15.3 0.0 2.5 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.17 EIE88610.1 - 2e-05 23.6 1.7 0.012 14.5 1.6 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A DAO PF01266.19 EIE88610.1 - 7.3e-05 21.8 0.1 0.00076 18.4 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EIE88610.1 - 0.0044 16.1 0.2 0.0077 15.3 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EIE88610.1 - 0.057 11.8 2.4 0.44 8.9 0.6 2.9 4 0 0 4 4 4 0 HI0933-like protein Pyr_redox_3 PF13738.1 EIE88610.1 - 0.19 11.7 3.4 2.4 8.1 1.4 3.1 2 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DnaJ-X PF14308.1 EIE88611.1 - 2.1e-50 170.8 7.5 2.1e-50 170.8 5.2 3.2 2 1 0 3 3 3 1 X-domain of DnaJ-containing Tropomyosin_1 PF12718.2 EIE88611.1 - 5e-31 107.4 34.8 5e-31 107.4 24.1 3.4 4 0 0 4 4 4 1 Tropomyosin like DnaJ PF00226.26 EIE88611.1 - 6.4e-22 77.0 1.3 3e-21 74.9 0.9 2.3 1 0 0 1 1 1 1 DnaJ domain Tropomyosin PF00261.15 EIE88611.1 - 4.4e-07 29.2 36.8 1.5e-06 27.5 12.3 3.7 3 2 1 4 4 4 2 Tropomyosin TPR_MLP1_2 PF07926.7 EIE88611.1 - 0.007 16.1 35.0 0.95 9.2 14.6 4.0 1 1 2 3 3 3 1 TPR/MLP1/MLP2-like protein Pox_A_type_inc PF04508.7 EIE88611.1 - 0.027 14.2 6.7 0.15 11.8 0.1 4.0 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Lectin_N PF03954.9 EIE88611.1 - 0.089 12.1 8.6 0.054 12.8 1.7 2.6 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain Glycohydro_20b2 PF14845.1 EIE88611.1 - 1.1 9.9 9.6 24 5.5 0.0 3.0 2 1 0 2 2 2 0 beta-acetyl hexosaminidase like Pro_isomerase PF00160.16 EIE88612.1 - 3.6e-40 137.6 0.2 7.9e-40 136.5 0.2 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD MIP-T3 PF10243.4 EIE88612.1 - 0.65 8.3 39.1 0.85 8.0 27.1 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Asp-B-Hydro_N PF05279.6 EIE88612.1 - 1.3 8.8 16.0 1.9 8.3 11.1 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region UPRTase PF14681.1 EIE88613.1 - 3.3e-56 189.7 0.0 9e-56 188.3 0.0 1.7 2 0 0 2 2 2 1 Uracil phosphoribosyltransferase PRK PF00485.13 EIE88613.1 - 8e-24 84.2 1.4 3.8e-23 82.0 0.2 2.5 2 1 1 3 3 3 1 Phosphoribulokinase / Uridine kinase family DUF4257 PF14074.1 EIE88613.1 - 0.019 14.6 0.7 0.052 13.1 0.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4257) SKG6 PF08693.5 EIE88614.1 - 0.059 12.6 1.9 0.2 11.0 1.3 2.0 1 0 0 1 1 1 0 Transmembrane alpha-helix domain RRM_1 PF00076.17 EIE88615.1 - 1.6e-29 101.3 0.2 3.2e-14 52.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MatE PF01554.13 EIE88615.1 - 1.1e-27 96.6 8.6 1.4e-27 96.2 6.0 1.1 1 0 0 1 1 1 1 MatE RRM_6 PF14259.1 EIE88615.1 - 4.4e-17 61.8 0.1 1.1e-08 34.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE88615.1 - 1.8e-06 27.6 0.0 0.0011 18.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EIE88615.1 - 0.00025 20.8 0.5 0.0069 16.2 0.0 2.2 1 1 1 2 2 2 1 RNA binding motif DUF566 PF04484.7 EIE88615.1 - 3.2 7.1 13.9 4.5 6.6 9.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) DUF1777 PF08648.7 EIE88615.1 - 6.8 6.3 39.6 11 5.6 27.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) MatE PF01554.13 EIE88616.1 - 1.2e-20 73.8 13.8 1.4e-20 73.5 9.6 1.1 1 0 0 1 1 1 1 MatE MOZ_SAS PF01853.13 EIE88617.1 - 2.2e-87 291.1 1.0 4.2e-87 290.2 0.7 1.4 1 0 0 1 1 1 1 MOZ/SAS family He_PIG_assoc PF10632.4 EIE88617.1 - 0.075 12.3 0.1 0.18 11.1 0.1 1.6 1 0 0 1 1 1 0 He_PIG associated, NEW1 domain of bacterial glycohydrolase Asp PF00026.18 EIE88619.1 - 2.9e-90 302.7 4.7 3.7e-90 302.4 3.3 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIE88619.1 - 1e-07 32.0 3.5 1.1e-06 28.7 0.5 3.2 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EIE88619.1 - 2e-06 28.2 0.5 0.021 15.3 0.0 2.8 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 EIE88619.1 - 0.00043 19.8 0.1 0.18 11.3 0.0 2.6 1 1 1 2 2 2 2 Xylanase inhibitor C-terminal EF-hand_7 PF13499.1 EIE88621.1 - 1.3e-19 70.0 3.9 8.2e-09 35.4 0.4 3.3 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 EIE88621.1 - 3.2e-18 63.5 9.6 3.7e-05 22.7 0.1 5.8 5 1 0 5 5 5 4 EF hand EF-hand_6 PF13405.1 EIE88621.1 - 5.4e-16 56.9 6.5 0.0004 20.0 0.1 4.8 5 0 0 5 5 5 3 EF-hand domain EF-hand_5 PF13202.1 EIE88621.1 - 7.7e-13 47.1 8.1 0.00013 21.1 0.0 4.5 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.1 EIE88621.1 - 2.4e-11 43.0 10.2 0.00083 18.9 0.3 4.9 2 2 3 5 5 5 5 EF-hand domain pair EF-hand_9 PF14658.1 EIE88621.1 - 0.015 15.2 0.1 0.36 10.7 0.0 2.7 3 0 0 3 3 3 0 EF-hand domain Toprim_2 PF13155.1 EIE88621.1 - 0.029 14.7 0.2 0.39 11.0 0.0 2.5 3 0 0 3 3 3 0 Toprim-like DHC_N2 PF08393.8 EIE88621.1 - 0.07 11.6 0.1 0.084 11.3 0.0 1.2 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 2 Bindin PF02084.10 EIE88621.1 - 0.51 10.3 5.5 0.64 10.0 3.8 1.1 1 0 0 1 1 1 0 Bindin Methyltransf_11 PF08241.7 EIE88622.1 - 1.2e-16 60.9 0.0 6.4e-16 58.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIE88622.1 - 2.3e-12 46.9 0.0 3.2e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIE88622.1 - 1.1e-11 45.2 0.0 1.8e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIE88622.1 - 3.8e-09 36.9 0.0 6e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIE88622.1 - 3.5e-08 33.1 0.0 6.1e-08 32.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIE88622.1 - 3.2e-05 23.1 0.0 5.1e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EIE88622.1 - 5.1e-05 23.5 0.0 8.5e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.7 EIE88622.1 - 0.00034 19.5 0.0 0.00047 19.1 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase MTS PF05175.9 EIE88622.1 - 0.00088 18.6 0.0 0.0032 16.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EIE88622.1 - 0.0012 18.8 0.0 0.017 15.1 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain RrnaAD PF00398.15 EIE88622.1 - 0.0058 15.6 0.0 0.0074 15.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_8 PF05148.10 EIE88622.1 - 0.01 15.4 0.0 0.018 14.7 0.0 1.3 1 1 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_PK PF05891.7 EIE88622.1 - 0.03 13.6 0.0 0.04 13.2 0.0 1.3 1 1 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Methyltransf_16 PF10294.4 EIE88622.1 - 0.033 13.6 0.0 0.07 12.5 0.0 1.5 1 1 0 1 1 1 0 Putative methyltransferase TehB PF03848.9 EIE88622.1 - 0.12 11.5 0.0 0.22 10.6 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB LON PF02190.11 EIE88623.1 - 9.2e-15 54.8 0.0 1.2e-14 54.5 0.0 1.1 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain Fork_head PF00250.13 EIE88624.1 - 1.3e-12 47.5 0.3 2.3e-12 46.8 0.2 1.3 1 0 0 1 1 1 1 Fork head domain YABBY PF04690.8 EIE88624.1 - 0.018 15.2 0.5 0.019 15.2 0.3 1.2 1 0 0 1 1 1 0 YABBY protein UMP1 PF05348.6 EIE88624.1 - 0.057 13.3 0.0 0.095 12.6 0.0 1.3 1 0 0 1 1 1 0 Proteasome maturation factor UMP1 RA PF00788.18 EIE88626.1 - 1.2e-13 51.3 0.1 1.9e-08 34.6 0.0 2.7 2 0 0 2 2 2 2 Ras association (RalGDS/AF-6) domain SH3_1 PF00018.23 EIE88626.1 - 5.7e-07 28.8 0.0 1.1e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EIE88626.1 - 0.014 14.9 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain THDPS_N PF14790.1 EIE88626.1 - 0.027 14.0 0.4 0.57 9.7 0.1 2.3 2 0 0 2 2 2 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal DUF3354 PF11834.3 EIE88626.1 - 0.062 12.9 0.0 4.9 6.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3354) SH3_3 PF08239.6 EIE88626.1 - 0.079 13.1 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain LAGLIDADG_1 PF00961.14 EIE88626.1 - 0.49 10.9 0.1 0.49 10.9 0.0 2.8 3 1 0 3 3 3 0 LAGLIDADG endonuclease LRR_6 PF13516.1 EIE88627.1 - 8e-06 25.4 15.5 1.6 9.0 0.0 6.7 7 0 0 7 7 7 3 Leucine Rich repeat LRR_1 PF00560.28 EIE88627.1 - 7.8e-05 22.1 12.2 0.14 12.2 0.0 6.4 6 2 0 6 6 6 2 Leucine Rich Repeat LRR_4 PF12799.2 EIE88627.1 - 0.0004 19.9 11.2 1.4 8.6 0.0 4.7 3 2 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EIE88627.1 - 0.003 17.2 10.0 0.021 14.5 1.6 3.9 4 1 0 4 4 4 2 Leucine rich repeat Serendipity_A PF05482.7 EIE88627.1 - 0.0081 14.6 0.1 0.011 14.1 0.1 1.1 1 0 0 1 1 1 1 Serendipity locus alpha protein (SRY-A) LRR_7 PF13504.1 EIE88627.1 - 0.02 15.0 12.2 1.9 9.0 0.0 5.7 4 2 0 4 4 4 0 Leucine rich repeat F-box-like PF12937.2 EIE88627.1 - 0.81 9.4 5.5 0.67 9.7 0.2 3.1 3 0 0 3 3 3 0 F-box-like Tubulin PF00091.20 EIE88628.1 - 1.9e-70 237.0 0.0 2.5e-70 236.6 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EIE88628.1 - 3e-48 163.0 0.0 4.6e-48 162.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EIE88628.1 - 0.00087 18.8 0.0 0.0015 18.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Neurochondrin PF05536.6 EIE88629.1 - 8.4e-33 113.4 6.9 1.2e-32 113.0 4.8 1.1 1 0 0 1 1 1 1 Neurochondrin zf-rbx1 PF12678.2 EIE88629.1 - 4.8e-18 65.0 12.0 3.9e-17 62.1 8.3 2.3 1 1 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EIE88629.1 - 2.8e-08 33.4 10.3 9.8e-07 28.5 7.1 2.3 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 EIE88629.1 - 4.7e-07 29.5 3.8 1.2e-06 28.2 2.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EIE88629.1 - 0.0015 18.1 3.3 0.0041 16.7 2.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIE88629.1 - 0.0018 18.2 2.1 0.0041 17.1 1.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) MOR2-PAG1_C PF14225.1 EIE88629.1 - 0.021 14.5 1.6 0.039 13.7 0.3 1.9 1 1 1 2 2 2 0 Cell morphogenesis C-terminal zf-C3HC4_3 PF13920.1 EIE88629.1 - 0.021 14.4 1.1 0.039 13.6 0.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIE88629.1 - 0.31 10.8 2.6 0.74 9.5 1.8 1.7 1 0 0 1 1 1 0 zinc-RING finger domain Opi1 PF08618.5 EIE88630.1 - 6.3e-49 167.0 10.6 3.6e-35 121.7 2.8 3.2 1 1 2 3 3 3 3 Transcription factor Opi1 Perilipin PF03036.11 EIE88630.1 - 2.4e-05 23.3 0.8 0.00032 19.6 0.0 2.5 2 1 0 2 2 2 1 Perilipin family Zip PF02535.17 EIE88630.1 - 1.7 7.5 5.3 2.5 7.0 3.7 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter RRM_6 PF14259.1 EIE88631.1 - 3.1e-29 100.7 0.2 2.1e-07 30.8 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EIE88631.1 - 3.7e-29 100.1 0.3 2.6e-10 39.7 0.1 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE88631.1 - 3e-21 75.0 2.9 9.9e-05 22.1 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EIE88631.1 - 0.087 12.6 0.0 3.1 7.6 0.0 3.0 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif HLH PF00010.21 EIE88632.1 - 2.2e-12 46.4 0.3 2.2e-12 46.4 0.2 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF2161 PF09929.4 EIE88632.1 - 0.067 13.1 1.7 0.14 12.1 0.2 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2161) GATA PF00320.22 EIE88633.1 - 8.8e-30 101.7 17.0 1.9e-16 59.0 3.3 2.5 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 EIE88633.1 - 1.9e-06 27.0 2.8 0.0036 16.5 0.5 2.7 2 0 0 2 2 2 2 TFIIB zinc-binding RRN7 PF11781.3 EIE88633.1 - 0.0059 16.0 0.2 0.0059 16.0 0.1 2.5 2 1 0 2 2 2 1 RNA polymerase I-specific transcription initiation factor Rrn7 eIF-5_eIF-2B PF01873.12 EIE88633.1 - 0.0094 15.6 5.9 0.082 12.5 0.3 2.7 3 0 0 3 3 3 2 Domain found in IF2B/IF5 Zn-ribbon_8 PF09723.5 EIE88633.1 - 0.051 13.5 2.3 3.7 7.5 0.1 2.7 2 0 0 2 2 2 0 Zinc ribbon domain DUF2248 PF10005.4 EIE88633.1 - 0.068 12.0 1.4 0.1 11.4 1.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2248) zf-CHY PF05495.7 EIE88633.1 - 0.2 11.8 4.1 1.4 9.0 2.2 2.3 1 1 1 2 2 2 0 CHY zinc finger DZR PF12773.2 EIE88633.1 - 0.21 11.4 8.4 6 6.7 0.6 2.9 1 1 2 3 3 3 0 Double zinc ribbon C1_3 PF07649.7 EIE88633.1 - 1.2 9.2 5.7 11 6.2 0.1 3.2 3 0 0 3 3 3 0 C1-like domain FYVE PF01363.16 EIE88633.1 - 1.7 8.6 6.9 6.4 6.7 4.7 2.1 1 1 0 1 1 1 0 FYVE zinc finger zf-C2H2_3 PF13878.1 EIE88633.1 - 3.1 7.4 10.6 4.5 6.9 0.2 4.0 3 1 1 4 4 4 0 zinc-finger of acetyl-transferase ESCO zf-Sec23_Sec24 PF04810.10 EIE88633.1 - 5.9 6.5 9.3 0.29 10.7 0.7 2.5 2 1 0 2 2 2 0 Sec23/Sec24 zinc finger TPR_1 PF00515.23 EIE88634.1 - 6.4e-14 50.8 2.3 1.9e-06 27.2 0.1 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 EIE88634.1 - 6.3e-12 44.3 0.7 0.011 15.4 0.0 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 EIE88634.1 - 3.1e-11 42.2 11.6 8.5e-06 25.3 0.1 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 EIE88634.1 - 6.9e-08 32.0 13.7 0.00082 18.9 0.0 4.7 4 1 0 5 5 5 2 TPR repeat TPR_12 PF13424.1 EIE88634.1 - 1.5e-07 31.2 5.9 0.0053 16.6 0.1 3.7 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EIE88634.1 - 8.1e-07 29.1 0.1 0.024 15.2 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat Apc3 PF12895.2 EIE88634.1 - 1.9e-06 27.9 19.6 3.7e-06 26.9 0.7 4.5 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 EIE88634.1 - 1.9e-06 28.1 1.4 0.012 15.9 0.0 4.6 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 EIE88634.1 - 2e-05 24.0 2.0 2 8.4 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 EIE88634.1 - 2.9e-05 24.2 1.2 0.013 15.8 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EIE88634.1 - 3.8e-05 24.2 4.6 0.057 14.1 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 EIE88634.1 - 0.0011 18.9 8.6 14 6.1 0.0 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_3 PF07720.7 EIE88634.1 - 0.011 15.5 1.8 0.12 12.1 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 EIE88634.1 - 0.028 14.3 4.6 4.4 7.3 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_21 PF09976.4 EIE88634.1 - 0.21 11.5 2.8 1.6 8.6 0.2 3.0 3 1 0 3 3 3 0 Tetratricopeptide repeat ATPase-cat_bd PF12156.3 EIE88635.1 - 0.08 13.4 0.0 0.08 13.4 0.0 1.1 1 0 0 1 1 1 0 Putative metal-binding domain of cation transport ATPase FBPase PF00316.15 EIE88636.1 - 7.1e-126 419.4 0.0 8e-126 419.2 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase Zn_clus PF00172.13 EIE88637.1 - 3.9e-08 33.0 7.4 6.9e-08 32.2 5.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_60s PF00428.14 EIE88637.1 - 0.38 11.1 6.3 0.81 10.1 4.3 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein K_channel_TID PF07941.6 EIE88637.1 - 0.77 10.0 11.3 1.1 9.5 6.7 2.0 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain IncA PF04156.9 EIE88637.1 - 4 6.9 6.3 3.9 7.0 3.2 1.6 1 1 1 2 2 2 0 IncA protein Ras PF00071.17 EIE88638.1 - 1.6e-26 92.5 0.3 1.9e-26 92.3 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIE88638.1 - 9.7e-07 29.3 0.1 2.1e-06 28.2 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EIE88638.1 - 3.2e-05 23.2 0.2 3.6e-05 23.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EIE88638.1 - 0.017 14.5 0.1 0.021 14.2 0.1 1.1 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain CAP_GLY PF01302.20 EIE88640.1 - 9.7e-13 47.6 0.7 1.6e-12 46.9 0.5 1.3 1 0 0 1 1 1 1 CAP-Gly domain UME PF08064.8 EIE88640.1 - 0.82 9.6 5.4 0.29 11.1 1.3 2.2 2 1 0 2 2 2 0 UME (NUC010) domain Reo_sigmaC PF04582.7 EIE88640.1 - 4.4 6.3 6.3 0.88 8.6 1.6 1.7 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DnaJ PF00226.26 EIE88641.1 - 5.3e-22 77.3 3.2 1.5e-21 75.8 1.4 2.4 2 0 0 2 2 2 1 DnaJ domain RRM_1 PF00076.17 EIE88641.1 - 0.0029 17.2 0.0 0.0066 16.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE88641.1 - 0.025 14.5 0.0 0.071 13.0 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF87 PF01935.12 EIE88641.1 - 1.9 8.2 5.1 3 7.6 3.6 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 Phlebovirus_NSM PF07246.6 EIE88641.1 - 4.9 6.2 11.5 1.3 8.0 6.0 1.5 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M HSP70 PF00012.15 EIE88641.1 - 7.4 4.3 11.7 2.7 5.7 5.6 1.8 2 0 0 2 2 2 0 Hsp70 protein eIF-6 PF01912.13 EIE88642.1 - 5.2e-86 286.8 0.6 7.8e-86 286.2 0.4 1.3 1 0 0 1 1 1 1 eIF-6 family DUF4119 PF13494.1 EIE88644.1 - 0.31 11.0 6.8 0.055 13.4 0.9 2.5 2 0 0 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF4119) UPF0086 PF01868.11 EIE88645.1 - 5e-27 93.3 1.1 1.5e-25 88.6 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function UPF0086 Ras PF00071.17 EIE88646.1 - 1.2e-54 184.1 0.0 1.4e-54 183.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIE88646.1 - 5.6e-14 52.6 0.0 8.5e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIE88646.1 - 5e-08 32.3 0.0 7.3e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EIE88646.1 - 0.0015 17.7 0.0 0.0022 17.2 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 EIE88646.1 - 0.0044 16.4 0.0 0.011 15.2 0.0 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EIE88646.1 - 0.04 13.0 0.0 0.044 12.9 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region UCH PF00443.24 EIE88648.1 - 5.9e-71 238.7 0.1 8.4e-71 238.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EIE88648.1 - 3.1e-23 82.6 0.1 1.7e-22 80.1 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-MIZ PF02891.15 EIE88648.1 - 0.036 13.5 0.1 0.094 12.2 0.0 1.7 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger CpXC PF14353.1 EIE88648.1 - 0.09 12.7 0.1 13 5.7 0.0 2.4 2 0 0 2 2 2 0 CpXC protein Homeobox PF00046.24 EIE88649.1 - 5.1e-19 67.6 1.8 9.3e-19 66.8 1.3 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EIE88649.1 - 0.039 13.6 0.2 0.14 11.9 0.1 2.0 1 0 0 1 1 1 0 Homeobox KN domain Septin PF00735.13 EIE88651.1 - 5.5e-125 416.0 0.7 5.5e-125 416.0 0.5 1.7 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 EIE88651.1 - 6.1e-09 35.8 0.0 1.3e-08 34.7 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EIE88651.1 - 5.7e-07 28.8 0.0 1.5e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EIE88651.1 - 1.2e-05 24.7 2.3 0.00032 20.1 0.0 2.9 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 EIE88651.1 - 1.9e-05 24.9 1.0 0.00076 19.7 0.0 2.5 2 0 0 2 2 2 1 ABC transporter AIG1 PF04548.11 EIE88651.1 - 0.00022 20.3 0.1 0.00022 20.3 0.0 1.8 2 0 0 2 2 2 1 AIG1 family AAA_22 PF13401.1 EIE88651.1 - 0.00027 21.0 0.0 0.0013 18.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain Gtr1_RagA PF04670.7 EIE88651.1 - 0.00079 18.6 0.0 0.0022 17.1 0.0 1.7 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 EIE88651.1 - 0.00091 18.6 2.2 0.0016 17.8 0.0 2.3 2 0 0 2 2 2 1 Ras family Miro PF08477.8 EIE88651.1 - 0.0011 19.4 2.3 0.0018 18.7 0.1 2.4 3 0 0 3 3 3 1 Miro-like protein AAA_10 PF12846.2 EIE88651.1 - 0.0018 17.8 0.1 0.0056 16.1 0.0 1.9 2 0 0 2 2 2 1 AAA-like domain Dynamin_N PF00350.18 EIE88651.1 - 0.0021 17.8 5.5 0.12 12.2 0.1 3.2 2 1 1 3 3 3 1 Dynamin family AAA_16 PF13191.1 EIE88651.1 - 0.0041 17.1 0.2 0.015 15.2 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 EIE88651.1 - 0.016 14.7 0.0 0.031 13.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Exonuc_VII_L PF02601.10 EIE88651.1 - 0.023 13.8 5.1 0.057 12.6 3.4 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit PduV-EutP PF10662.4 EIE88651.1 - 0.027 13.9 0.3 0.37 10.2 0.1 2.8 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.17 EIE88651.1 - 0.14 12.3 0.4 0.53 10.4 0.0 2.2 2 1 1 3 3 2 0 RNA helicase FtsK_SpoIIIE PF01580.13 EIE88651.1 - 0.36 10.2 0.0 0.36 10.2 0.0 2.4 3 0 0 3 3 3 0 FtsK/SpoIIIE family ATP_bind_1 PF03029.12 EIE88651.1 - 1.1 8.7 4.0 17 4.8 0.0 3.1 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein DUF2937 PF11157.3 EIE88651.1 - 1.8 7.8 4.4 3.2 7.0 3.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) IncA PF04156.9 EIE88651.1 - 1.9 8.0 6.7 3.3 7.2 4.7 1.5 1 0 0 1 1 1 0 IncA protein Atg14 PF10186.4 EIE88651.1 - 3.5 6.4 7.4 5.5 5.8 5.1 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Hexokinase_2 PF03727.11 EIE88652.1 - 1.2e-78 263.7 0.2 1.6e-78 263.2 0.1 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EIE88652.1 - 3.7e-72 241.9 0.2 6.6e-72 241.1 0.1 1.4 1 0 0 1 1 1 1 Hexokinase CsbD PF05532.7 EIE88654.1 - 2.1e-16 59.2 18.9 3.7e-12 45.7 4.3 2.0 1 1 1 2 2 2 2 CsbD-like PCNA_N PF00705.13 EIE88655.1 - 2.5e-54 182.1 3.4 5e-54 181.1 2.4 1.5 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 EIE88655.1 - 1.1e-50 170.8 0.2 1.6e-50 170.3 0.2 1.2 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.8 EIE88655.1 - 4.2e-09 35.9 0.1 5.4e-09 35.5 0.1 1.1 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.11 EIE88655.1 - 2.2e-08 33.2 1.2 1.1e-06 27.6 0.8 2.1 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Hus1 PF04005.7 EIE88655.1 - 3.2e-05 23.0 0.2 0.0039 16.1 0.0 2.1 2 0 0 2 2 2 2 Hus1-like protein ADK PF00406.17 EIE88656.1 - 2.5e-60 202.7 0.0 3.3e-60 202.3 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 EIE88656.1 - 1e-15 57.0 0.0 2.1e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.1 EIE88656.1 - 0.00032 21.4 0.0 0.00086 20.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EIE88656.1 - 0.0021 17.9 0.0 0.0037 17.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EIE88656.1 - 0.0095 16.2 0.0 0.03 14.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EIE88656.1 - 0.037 13.1 0.2 0.063 12.3 0.1 1.6 1 1 0 1 1 1 0 Zeta toxin DUF2443 PF10398.4 EIE88656.1 - 0.1 12.3 1.0 5.3 6.9 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2443) Arm PF00514.18 EIE88657.1 - 4.5e-06 26.2 9.0 0.00045 19.9 0.1 4.2 4 0 0 4 4 4 3 Armadillo/beta-catenin-like repeat GPI-anchored PF10342.4 EIE88658.1 - 0.073 13.5 0.1 0.1 13.1 0.0 1.2 1 0 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family SRP54 PF00448.17 EIE88659.1 - 6.5e-77 257.4 1.1 1.2e-76 256.5 0.8 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.14 EIE88659.1 - 4.9e-14 52.1 5.6 6.5e-14 51.7 2.7 2.2 2 0 0 2 2 1 1 SRP54-type protein, helical bundle domain SRP_SPB PF02978.14 EIE88659.1 - 1.2e-12 48.0 1.5 1.2e-12 48.0 1.0 3.0 2 0 0 2 2 2 1 Signal peptide binding domain cobW PF02492.14 EIE88659.1 - 1.4e-08 34.3 0.1 3.4e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 EIE88659.1 - 1.3e-05 25.0 0.0 3.8e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 EIE88659.1 - 2.7e-05 23.8 0.2 9.9e-05 22.0 0.0 2.1 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.18 EIE88659.1 - 0.00045 19.6 0.3 0.0023 17.3 0.1 2.2 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain Zeta_toxin PF06414.7 EIE88659.1 - 0.0013 17.9 0.0 0.003 16.6 0.0 1.6 1 1 0 1 1 1 1 Zeta toxin AAA_17 PF13207.1 EIE88659.1 - 0.0018 19.1 0.3 0.012 16.4 0.0 2.6 3 1 0 3 3 1 1 AAA domain ArgK PF03308.11 EIE88659.1 - 0.011 14.5 0.2 0.059 12.1 0.0 2.3 1 1 1 2 2 2 0 ArgK protein AAA_30 PF13604.1 EIE88659.1 - 0.015 14.9 0.0 0.033 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EIE88659.1 - 0.015 15.4 0.7 0.14 12.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 EIE88659.1 - 0.048 13.1 1.1 0.13 11.7 0.1 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_31 PF13614.1 EIE88659.1 - 0.062 13.2 0.0 17 5.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.15 EIE88659.1 - 0.07 12.7 0.0 0.2 11.3 0.0 1.7 1 0 0 1 1 1 0 Adenylylsulphate kinase Thymidylate_kin PF02223.12 EIE88659.1 - 0.09 12.1 1.2 0.28 10.5 0.1 2.4 3 0 0 3 3 3 0 Thymidylate kinase AAA_16 PF13191.1 EIE88659.1 - 0.1 12.5 0.0 0.35 10.8 0.0 1.9 1 1 1 2 2 2 0 AAA ATPase domain AAA_19 PF13245.1 EIE88659.1 - 0.1 12.3 0.0 0.28 10.9 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain RasGAP PF00616.14 EIE88660.1 - 3.3e-54 183.5 0.2 8.6e-54 182.2 0.0 1.9 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 EIE88660.1 - 7.1e-31 106.7 2.5 7.1e-31 106.7 1.7 2.1 2 0 0 2 2 2 1 RasGAP C-terminus DUF972 PF06156.8 EIE88660.1 - 0.013 15.8 6.3 0.54 10.6 0.2 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF972) RNase_P_p30 PF01876.11 EIE88660.1 - 0.062 12.5 0.1 0.26 10.5 0.0 2.0 2 0 0 2 2 2 0 RNase P subunit p30 MitMem_reg PF13012.1 EIE88660.1 - 0.4 10.7 5.2 0.26 11.3 0.3 2.9 3 0 0 3 3 3 0 Maintenance of mitochondrial structure and function Sugar_tr PF00083.19 EIE88661.1 - 2.5e-103 346.0 31.2 8.7e-101 337.7 21.6 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIE88661.1 - 3.6e-28 98.2 55.1 2.6e-24 85.5 18.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 EIE88661.1 - 0.41 8.6 11.2 0.42 8.6 1.0 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector Vma12 PF11712.3 EIE88661.1 - 0.67 9.6 3.2 2 8.1 0.0 2.9 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase RRM_1 PF00076.17 EIE88662.1 - 1.1e-19 69.8 5.1 8.3e-15 54.1 0.0 3.7 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE88662.1 - 6.7e-10 38.8 0.1 4.9e-08 32.8 0.0 2.8 2 1 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE88662.1 - 7.2e-08 32.1 0.1 0.0031 17.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sec20 PF03908.8 EIE88665.1 - 3.5e-20 71.5 2.5 3.5e-20 71.5 1.8 2.8 2 1 1 3 3 3 1 Sec20 DUF4407 PF14362.1 EIE88665.1 - 0.0015 17.5 5.4 0.0021 17.0 3.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) HOASN PF14515.1 EIE88665.1 - 0.0096 16.2 0.4 0.02 15.2 0.3 1.5 1 0 0 1 1 1 1 Haem-oxygenase-associated N-terminal helices Imm43 PF15602.1 EIE88665.1 - 0.018 15.0 0.0 0.031 14.2 0.0 1.3 1 1 0 1 1 1 0 Immunity protein 43 MobC PF05713.6 EIE88665.1 - 0.1 12.5 0.3 0.69 9.9 0.1 2.3 2 0 0 2 2 2 0 Bacterial mobilisation protein (MobC) zf-C4pol PF14260.1 EIE88665.1 - 0.92 9.5 3.0 5.2 7.1 0.6 2.7 1 1 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta ACCA PF03255.9 EIE88665.1 - 3.4 7.1 6.5 0.97 8.9 1.2 2.4 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit ABC_tran PF00005.22 EIE88666.1 - 1.6e-35 122.4 0.1 2.2e-17 63.6 0.0 2.9 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EIE88666.1 - 3.4e-12 46.9 14.6 0.0058 16.6 0.1 4.8 3 2 2 5 5 5 4 AAA domain SMC_N PF02463.14 EIE88666.1 - 4.4e-11 42.4 5.2 0.00084 18.6 0.4 3.9 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain Fer4 PF00037.22 EIE88666.1 - 6.7e-09 34.9 2.8 1.3e-08 34.0 1.9 1.4 1 0 0 1 1 1 1 4Fe-4S binding domain AAA_15 PF13175.1 EIE88666.1 - 4.6e-07 29.2 3.7 0.86 8.5 0.2 4.2 3 1 1 4 4 4 2 AAA ATPase domain AAA_29 PF13555.1 EIE88666.1 - 1.4e-06 27.7 0.5 0.048 13.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain Fer4_6 PF12837.2 EIE88666.1 - 6e-06 25.9 1.1 1.1e-05 25.0 0.8 1.4 1 0 0 1 1 1 1 4Fe-4S binding domain DUF258 PF03193.11 EIE88666.1 - 2.1e-05 23.7 0.0 0.077 12.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 EIE88666.1 - 5.4e-05 23.9 0.4 0.43 11.4 0.0 2.8 2 2 0 2 2 2 2 AAA domain Fer4_21 PF14697.1 EIE88666.1 - 0.00016 21.4 1.8 0.00032 20.5 1.2 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_18 PF13238.1 EIE88666.1 - 0.00027 21.2 0.1 0.27 11.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain Fer4_7 PF12838.2 EIE88666.1 - 0.0004 20.7 0.3 0.00082 19.7 0.2 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA PF00004.24 EIE88666.1 - 0.00055 20.1 0.0 1.4 9.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Fer4_9 PF13187.1 EIE88666.1 - 0.00062 19.9 0.3 0.0014 18.8 0.2 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_16 PF13191.1 EIE88666.1 - 0.00083 19.3 0.2 0.11 12.4 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain Fer4_2 PF12797.2 EIE88666.1 - 0.0011 18.7 1.8 0.0022 17.7 1.2 1.5 1 0 0 1 1 1 1 4Fe-4S binding domain Fer4_10 PF13237.1 EIE88666.1 - 0.0013 18.4 0.2 0.0023 17.6 0.2 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.1 EIE88666.1 - 0.0014 19.3 0.1 0.0027 18.4 0.1 1.5 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain VirE PF05272.6 EIE88666.1 - 0.002 17.6 0.0 0.96 8.8 0.0 2.4 2 0 0 2 2 2 1 Virulence-associated protein E Miro PF08477.8 EIE88666.1 - 0.0028 18.1 0.1 0.39 11.2 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein AAA_22 PF13401.1 EIE88666.1 - 0.0034 17.5 0.0 0.48 10.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EIE88666.1 - 0.0042 16.9 0.0 0.24 11.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.12 EIE88666.1 - 0.0044 16.4 0.2 4.5 6.5 0.0 3.3 3 0 0 3 3 3 0 Thymidylate kinase NACHT PF05729.7 EIE88666.1 - 0.0046 16.6 0.6 0.72 9.4 0.0 2.5 2 0 0 2 2 2 1 NACHT domain RNA_helicase PF00910.17 EIE88666.1 - 0.0059 16.7 0.1 3 8.0 0.0 2.7 2 0 0 2 2 2 1 RNA helicase Rad17 PF03215.10 EIE88666.1 - 0.0062 15.2 0.0 0.085 11.5 0.0 2.1 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein MobB PF03205.9 EIE88666.1 - 0.0075 15.9 1.2 0.79 9.4 0.0 2.7 3 0 0 3 3 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.9 EIE88666.1 - 0.0089 15.7 0.4 0.42 10.3 0.0 2.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Fer4_8 PF13183.1 EIE88666.1 - 0.011 15.7 0.1 0.022 14.8 0.1 1.4 1 0 0 1 1 1 0 4Fe-4S dicluster domain SRP54 PF00448.17 EIE88666.1 - 0.011 15.1 1.1 1 8.7 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_25 PF13481.1 EIE88666.1 - 0.013 14.8 0.0 5.5 6.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 EIE88666.1 - 0.019 14.9 0.1 4.7 7.2 0.0 3.3 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Fer4_17 PF13534.1 EIE88666.1 - 0.019 15.3 0.1 0.045 14.1 0.1 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain AAA_23 PF13476.1 EIE88666.1 - 0.02 15.2 5.4 0.04 14.2 0.1 2.6 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 EIE88666.1 - 0.027 14.4 0.0 2.8 7.9 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase Fer4_3 PF12798.2 EIE88666.1 - 0.031 14.8 5.2 0.061 13.9 3.6 1.5 1 0 0 1 1 1 0 4Fe-4S binding domain Fer4_4 PF12800.2 EIE88666.1 - 0.032 14.5 2.1 0.061 13.6 1.5 1.4 1 0 0 1 1 1 0 4Fe-4S binding domain Fer4_18 PF13746.1 EIE88666.1 - 0.039 14.3 0.9 0.087 13.2 0.6 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_15 PF13459.1 EIE88666.1 - 0.045 14.3 0.8 0.11 13.1 0.6 1.7 1 0 0 1 1 1 0 4Fe-4S single cluster domain ArgK PF03308.11 EIE88666.1 - 0.057 12.2 0.1 2.4 6.8 0.0 2.2 2 0 0 2 2 2 0 ArgK protein AAA_28 PF13521.1 EIE88666.1 - 0.1 12.5 0.6 5.9 6.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EIE88666.1 - 0.1 12.4 0.7 10 6.0 0.0 3.1 2 1 0 2 2 2 0 AAA domain DUF815 PF05673.8 EIE88666.1 - 0.11 11.4 0.2 5.1 5.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_30 PF13604.1 EIE88666.1 - 0.11 12.0 0.0 3 7.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EIE88666.1 - 0.19 11.1 1.5 9.5 5.5 0.0 2.8 3 0 0 3 3 3 0 AAA-like domain AAA_13 PF13166.1 EIE88666.1 - 0.19 10.1 0.8 0.42 9.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain HD_3 PF13023.1 EIE88667.1 - 8e-08 32.1 0.1 8e-08 32.1 0.0 1.0 1 0 0 1 1 1 1 HD domain Macoilin PF09726.4 EIE88668.1 - 0.035 12.4 0.0 0.041 12.1 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein Pkinase PF00069.20 EIE88670.1 - 1.2e-47 162.2 0.4 2.1e-42 145.0 0.0 2.4 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIE88670.1 - 1.1e-13 50.8 0.0 4.7e-10 38.9 0.0 2.4 1 1 1 2 2 2 2 Protein tyrosine kinase RIO1 PF01163.17 EIE88670.1 - 0.085 12.1 0.1 0.18 11.1 0.1 1.6 1 0 0 1 1 1 0 RIO1 family MORN_2 PF07661.8 EIE88670.1 - 0.21 11.7 0.7 30 5.0 0.0 2.7 2 0 0 2 2 2 0 MORN repeat variant zf-C2H2 PF00096.21 EIE88671.1 - 4.4e-12 45.5 8.6 1.6e-06 28.0 0.8 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIE88671.1 - 2.5e-10 40.1 8.6 5.3e-08 32.7 0.2 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EIE88671.1 - 4.9e-09 35.8 11.2 1.8e-05 24.7 0.9 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EIE88671.1 - 1.6e-06 28.0 2.1 0.011 15.8 0.1 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EIE88671.1 - 0.0068 16.4 4.6 0.091 12.8 0.3 2.5 1 1 1 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 EIE88671.1 - 0.017 15.3 2.7 1.1 9.5 0.1 2.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-BED PF02892.10 EIE88671.1 - 0.026 14.2 8.3 0.17 11.6 0.6 2.6 1 1 1 2 2 2 0 BED zinc finger zf-CHY PF05495.7 EIE88671.1 - 0.15 12.2 3.9 0.31 11.2 2.7 1.5 1 0 0 1 1 1 0 CHY zinc finger zf-C2H2_6 PF13912.1 EIE88671.1 - 0.21 11.5 1.6 0.73 9.8 0.0 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2HC_2 PF13913.1 EIE88671.1 - 0.89 9.3 8.7 2.6 7.7 0.5 3.2 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-TRAF PF02176.13 EIE88671.1 - 1.9 8.9 5.7 2.3 8.6 3.2 1.7 1 1 0 1 1 1 0 TRAF-type zinc finger Molybdopterin PF00384.17 EIE88673.1 - 1.3e-69 235.0 0.0 9.1e-69 232.2 0.0 2.0 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.1 EIE88673.1 - 1.8e-18 66.0 0.2 1.2e-17 63.5 0.1 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.4 EIE88673.1 - 5.3e-18 63.9 0.1 1.3e-17 62.7 0.1 1.7 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region DUF1982 PF09326.6 EIE88673.1 - 8.5e-15 54.6 0.1 2.1e-14 53.3 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1982) Fer2 PF00111.22 EIE88673.1 - 5e-08 32.5 0.4 5e-08 32.5 0.2 1.8 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.17 EIE88673.1 - 0.0053 16.5 0.0 1.1 9.0 0.0 2.8 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain Metallophos PF00149.23 EIE88674.1 - 2.1e-41 141.5 0.2 3.5e-41 140.8 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Zds_C PF08632.5 EIE88675.1 - 3.3e-21 74.4 3.3 5.5e-21 73.7 0.2 2.3 2 0 0 2 2 2 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term UCH PF00443.24 EIE88677.1 - 1.3e-52 178.6 0.0 1.6e-52 178.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EIE88677.1 - 4e-19 69.1 4.2 1.4e-18 67.3 2.9 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 EIE88677.1 - 3.5e-09 35.9 0.0 1.1e-08 34.3 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin family CLTH PF10607.4 EIE88678.1 - 9.6e-09 35.0 1.6 1.4e-08 34.5 0.2 1.8 1 1 1 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain Med2 PF11214.3 EIE88678.1 - 0.015 15.3 0.4 0.019 14.9 0.3 1.3 1 0 0 1 1 1 0 Mediator complex subunit 2 Tau95 PF09734.4 EIE88678.1 - 0.034 13.4 0.2 0.035 13.4 0.2 1.1 1 0 0 1 1 1 0 RNA polymerase III transcription factor (TF)IIIC subunit Imm28 PF15574.1 EIE88678.1 - 0.06 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 28 ALIX_LYPXL_bnd PF13949.1 EIE88679.1 - 0.00031 19.8 31.3 0.00048 19.1 21.7 1.3 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV Filament PF00038.16 EIE88679.1 - 0.00051 19.6 43.6 0.00068 19.2 30.2 1.1 1 0 0 1 1 1 1 Intermediate filament protein Tropomyosin PF00261.15 EIE88679.1 - 0.0058 15.7 12.5 0.0058 15.7 8.6 2.8 1 1 1 2 2 2 1 Tropomyosin Mitofilin PF09731.4 EIE88679.1 - 0.04 12.5 42.0 0.048 12.3 29.1 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein CorA PF01544.13 EIE88679.1 - 0.24 10.4 26.1 0.25 10.3 1.9 3.0 1 1 2 3 3 3 0 CorA-like Mg2+ transporter protein Laminin_II PF06009.7 EIE88679.1 - 0.25 11.0 35.0 0.074 12.8 4.9 3.6 1 1 3 4 4 4 0 Laminin Domain II MutS_III PF05192.13 EIE88679.1 - 0.33 10.6 20.2 0.12 12.1 9.4 2.4 1 1 1 2 2 2 0 MutS domain III ROK PF00480.15 EIE88679.1 - 0.35 10.6 7.0 0.32 10.7 0.1 2.6 1 1 2 3 3 3 0 ROK family ATG16 PF08614.6 EIE88679.1 - 0.38 10.5 45.8 0.18 11.6 7.4 2.6 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) TMCO5 PF14992.1 EIE88679.1 - 0.6 9.1 44.5 0.3 10.1 3.3 3.1 1 1 2 3 3 3 0 TMCO5 family Pneumovirus_M2 PF06436.6 EIE88679.1 - 0.63 9.2 9.1 1 8.5 4.5 2.3 1 1 1 2 2 2 0 Pneumovirus matrix protein 2 (M2) DASH_Dam1 PF08653.5 EIE88679.1 - 0.87 9.4 3.8 32 4.3 0.0 3.8 4 0 0 4 4 4 0 DASH complex subunit Dam1 BicD PF09730.4 EIE88679.1 - 0.92 7.7 46.3 0.45 8.8 21.6 2.0 1 1 1 2 2 2 0 Microtubule-associated protein Bicaudal-D CENP-F_leu_zip PF10473.4 EIE88679.1 - 1 9.1 50.5 3.3 7.5 3.7 3.7 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MscS_porin PF12795.2 EIE88679.1 - 2 7.6 53.3 0.044 13.1 10.5 3.0 1 1 2 3 3 3 0 Mechanosensitive ion channel porin domain S-AdoMet_synt_M PF02772.11 EIE88679.1 - 2.3 8.1 9.6 0.64 9.9 3.6 2.3 1 1 2 3 3 3 0 S-adenosylmethionine synthetase, central domain APG6 PF04111.7 EIE88679.1 - 2.7 6.9 51.1 1.2 8.0 10.6 2.3 1 1 1 2 2 2 0 Autophagy protein Apg6 IncA PF04156.9 EIE88679.1 - 9.1 5.8 50.2 0.47 10.0 14.1 2.7 1 1 2 3 3 3 0 IncA protein AATF-Che1 PF13339.1 EIE88679.1 - 9.2 6.4 38.7 6.4 6.9 3.4 3.8 1 1 3 4 4 4 0 Apoptosis antagonizing transcription factor GAS PF13851.1 EIE88679.1 - 9.3 5.3 49.3 0.41 9.8 7.3 2.9 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding CCD PF07860.6 EIE88680.1 - 2.7 7.4 5.6 1.6 8.1 0.9 2.4 1 1 0 2 2 2 0 WisP family C-Terminal Region Peptidase_C14 PF00656.17 EIE88683.1 - 1.9e-39 135.8 0.1 3.4e-37 128.4 0.0 2.4 1 1 0 1 1 1 1 Caspase domain Fungal_trans PF04082.13 EIE88683.1 - 1.1e-26 93.2 0.0 2.4e-26 92.1 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Acyl-CoA_dh_1 PF00441.19 EIE88684.1 - 2.9e-47 160.5 2.8 4.8e-47 159.8 2.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EIE88684.1 - 7.3e-23 81.2 0.0 1.9e-22 79.9 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EIE88684.1 - 3.2e-21 75.9 0.4 6.1e-21 75.0 0.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EIE88684.1 - 1.4e-19 69.3 0.1 5.2e-19 67.4 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain GN3L_Grn1 PF08701.6 EIE88685.1 - 1.2e-14 54.0 13.7 1.6e-14 53.5 9.5 1.2 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase Stn1 PF10451.4 EIE88685.1 - 0.24 10.2 4.9 0.24 10.2 3.4 1.0 1 0 0 1 1 1 0 Telomere regulation protein Stn1 ATP-synt_E PF05680.7 EIE88685.1 - 0.79 9.7 6.4 1.1 9.3 4.5 1.3 1 0 0 1 1 1 0 ATP synthase E chain Arteri_nucleo PF01481.11 EIE88685.1 - 1.6 8.8 4.0 1.9 8.6 2.8 1.1 1 0 0 1 1 1 0 Arterivirus nucleocapsid protein DUF4337 PF14235.1 EIE88685.1 - 1.8 8.3 3.9 1.9 8.3 2.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF3987 PF13148.1 EIE88685.1 - 2.3 6.6 9.7 2.6 6.5 6.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) DUF3340 PF11818.3 EIE88685.1 - 2.4 8.0 10.7 3.3 7.6 7.4 1.2 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) Utp21 PF04192.7 EIE88685.1 - 3.4 6.7 8.9 3.6 6.6 6.2 1.0 1 0 0 1 1 1 0 Utp21 specific WD40 associated putative domain CRAL_TRIO PF00650.15 EIE88687.1 - 1.3e-16 60.5 0.2 2.2e-16 59.7 0.1 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 EIE88687.1 - 0.004 17.0 2.1 0.012 15.5 0.3 2.4 2 1 0 2 2 2 1 Divergent CRAL/TRIO domain DUF244 PF03112.9 EIE88687.1 - 0.044 13.3 3.5 0.11 12.0 2.4 1.7 1 0 0 1 1 1 0 Uncharacterized protein family (ORF7) DUF Abhydrolase_3 PF07859.8 EIE88688.1 - 5.2e-20 71.9 0.0 7.4e-19 68.1 0.0 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EIE88688.1 - 4.7e-10 38.6 0.0 1.4e-09 37.0 0.0 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF2424) Peptidase_S9 PF00326.16 EIE88688.1 - 0.00052 19.2 0.0 0.0011 18.2 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase_phd PF10503.4 EIE88688.1 - 0.021 14.0 0.0 0.039 13.1 0.0 1.4 1 0 0 1 1 1 0 Esterase PHB depolymerase DUF2974 PF11187.3 EIE88688.1 - 0.044 13.1 0.0 0.077 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.2 EIE88688.1 - 0.056 13.2 0.0 0.077 12.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family RRM_1 PF00076.17 EIE88689.1 - 5.8e-27 93.1 0.6 2.3e-13 49.5 0.1 3.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE88689.1 - 5e-24 84.0 0.1 1.2e-10 41.2 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE88689.1 - 2.1e-08 33.9 0.0 0.0037 17.0 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pap_E4 PF02711.9 EIE88689.1 - 8.6 7.2 16.4 24 5.8 0.6 2.5 2 0 0 2 2 2 0 E4 protein DUF3658 PF12395.3 EIE88690.1 - 0.049 13.1 1.1 0.073 12.6 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function GDPD PF03009.12 EIE88690.1 - 0.1 12.0 0.4 0.24 10.8 0.2 1.6 1 1 1 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family GWT1 PF06423.7 EIE88690.1 - 0.26 11.3 1.5 0.68 10.0 0.2 2.0 1 1 1 2 2 2 0 GWT1 PilJ PF13675.1 EIE88690.1 - 0.28 11.4 4.0 0.75 10.1 0.3 2.7 2 1 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term NUDIX PF00293.23 EIE88692.1 - 1e-15 57.5 0.1 1.4e-15 57.1 0.1 1.2 1 0 0 1 1 1 1 NUDIX domain Ribosomal_S28e PF01200.13 EIE88694.1 - 5.7e-34 115.6 2.6 6.2e-34 115.5 1.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e NmrA PF05368.8 EIE88695.1 - 3.4e-14 52.6 0.0 3.3e-08 33.0 0.0 2.1 2 0 0 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.1 EIE88695.1 - 9.8e-14 51.7 0.0 1.4e-13 51.2 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EIE88695.1 - 7.9e-05 22.1 0.0 0.00013 21.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 EIE88695.1 - 0.00029 20.7 0.0 0.0007 19.5 0.0 1.7 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_2 PF03446.10 EIE88695.1 - 0.0018 18.0 0.0 0.0029 17.4 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EIE88695.1 - 0.024 15.0 0.0 0.092 13.1 0.0 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.1 EIE88695.1 - 0.027 14.7 0.0 0.14 12.4 0.0 2.0 2 1 0 2 2 2 0 Putative NAD(P)-binding adh_short PF00106.20 EIE88695.1 - 0.035 14.0 0.0 0.059 13.2 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase 3Beta_HSD PF01073.14 EIE88695.1 - 0.037 12.7 0.0 0.062 11.9 0.0 1.4 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 EIE88695.1 - 0.069 13.4 0.2 0.42 10.9 0.1 2.4 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain FA_hydroxylase PF04116.8 EIE88696.1 - 1.4e-12 47.9 22.3 1.4e-12 47.9 15.4 2.3 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Melibiase PF02065.13 EIE88697.1 - 3.6e-17 62.1 1.0 5.2e-17 61.6 0.7 1.1 1 0 0 1 1 1 1 Melibiase Glyco_hydro_31 PF01055.21 EIE88697.1 - 1.3e-12 47.3 0.2 1.7e-12 46.9 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 GHL6 PF14871.1 EIE88697.1 - 0.00035 20.5 0.0 0.079 12.9 0.0 2.4 2 0 0 2 2 2 2 Hypothetical glycosyl hydrolase 6 Raffinose_syn PF05691.7 EIE88697.1 - 0.0021 15.6 0.1 0.0033 15.0 0.0 1.2 1 0 0 1 1 1 1 Raffinose synthase or seed imbibition protein Sip1 DUF1581 PF07619.6 EIE88697.1 - 0.049 13.6 0.2 5.6 7.0 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1581) Ubie_methyltran PF01209.13 EIE88698.1 - 1.7e-82 276.0 0.0 2.1e-82 275.7 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EIE88698.1 - 5.1e-15 55.3 0.0 9.4e-15 54.5 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIE88698.1 - 9.3e-14 51.6 0.0 1.8e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIE88698.1 - 4e-11 42.9 0.0 6.1e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIE88698.1 - 9.6e-11 42.0 0.0 1.9e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIE88698.1 - 4.7e-09 36.5 0.0 1.1e-08 35.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIE88698.1 - 1.1e-07 32.4 0.0 2e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIE88698.1 - 0.00015 21.7 0.0 0.00038 20.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EIE88698.1 - 0.0013 18.3 0.3 0.0077 15.8 0.0 2.2 2 1 0 2 2 2 1 Hypothetical methyltransferase Methyltransf_28 PF02636.12 EIE88698.1 - 0.003 16.9 0.0 0.0045 16.4 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase DUF3577 PF12101.3 EIE88698.1 - 0.032 14.1 0.0 0.085 12.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3577) STN1_2 PF09170.5 EIE88698.1 - 0.036 13.8 0.1 7.4 6.3 0.1 2.2 2 0 0 2 2 2 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 Ecl1 PF12855.2 EIE88700.1 - 1.3e-08 33.9 4.7 2.2e-08 33.2 3.3 1.3 1 0 0 1 1 1 1 Life-span regulatory factor DUF2116 PF09889.4 EIE88700.1 - 0.26 11.1 2.6 0.48 10.2 1.8 1.4 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) RGS PF00615.14 EIE88701.1 - 1.2e-07 31.8 1.3 1.4e-06 28.3 0.3 2.7 2 1 0 2 2 2 1 Regulator of G protein signaling domain Neurensin PF14927.1 EIE88701.1 - 0.0065 15.8 0.1 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Neurensin Tetraspannin PF00335.15 EIE88701.1 - 0.055 12.7 8.1 0.09 12.0 5.6 1.2 1 0 0 1 1 1 0 Tetraspanin family SdpI PF13630.1 EIE88701.1 - 2.7 7.7 15.7 0.93 9.2 0.5 3.8 3 1 0 3 3 3 0 SdpI/YhfL protein family HSP90 PF00183.13 EIE88702.1 - 1.7e-75 254.4 0.9 1.7e-75 254.4 0.6 2.3 2 1 1 3 3 3 2 Hsp90 protein HATPase_c_3 PF13589.1 EIE88702.1 - 4.8e-13 48.9 0.2 1.5e-12 47.3 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EIE88702.1 - 7.5e-07 28.8 0.1 2e-06 27.4 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF4159 PF13709.1 EIE88702.1 - 0.043 12.9 0.1 0.33 10.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4159) RVT_1 PF00078.22 EIE88703.1 - 6.2e-21 74.7 0.1 1.1e-19 70.5 0.0 2.3 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) ASFV_L11L PF05293.6 EIE88703.1 - 1.1 9.4 4.1 4.5 7.4 0.3 3.3 3 0 0 3 3 3 0 African swine fever virus (ASFV) L11L protein Exo_endo_phos_2 PF14529.1 EIE88704.1 - 6.2e-12 45.1 0.9 6.2e-12 45.1 0.6 2.4 2 1 1 3 3 3 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EIE88704.1 - 3.6e-10 40.1 3.0 9.1e-10 38.8 2.1 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-CCHC PF00098.18 EIE88704.1 - 4.3e-07 29.5 10.0 3.8e-05 23.4 0.7 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 EIE88704.1 - 0.001 18.6 3.3 0.31 10.7 0.2 2.6 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.1 EIE88704.1 - 0.0052 16.2 1.8 0.0052 16.2 1.2 2.2 1 1 1 2 2 2 1 Zinc knuckle zf-CCHC_6 PF15288.1 EIE88704.1 - 1 9.1 8.6 3.6 7.3 1.0 2.5 1 1 1 2 2 2 0 Zinc knuckle TBCA PF02970.11 EIE88705.1 - 0.14 12.2 1.7 1.7 8.7 0.1 2.9 1 1 1 2 2 2 0 Tubulin binding cofactor A Drc1-Sld2 PF11719.3 EIE88707.1 - 0.013 14.5 1.9 0.017 14.2 1.3 1.2 1 0 0 1 1 1 0 DNA replication and checkpoint protein PLRV_ORF5 PF01690.12 EIE88707.1 - 0.042 13.0 1.4 0.043 12.9 0.9 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF4519 PF15012.1 EIE88707.1 - 2.2 8.2 6.4 0.3 11.0 1.4 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4519) DDE_3 PF13358.1 EIE88708.1 - 6.2e-20 71.4 0.0 1.5e-19 70.2 0.0 1.6 1 1 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE88708.1 - 0.0061 16.6 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain DDE_1 PF03184.14 EIE88708.1 - 0.097 11.7 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease Exo_endo_phos PF03372.18 EIE88709.1 - 5.7e-12 46.0 0.3 9.5e-12 45.3 0.2 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family NAD_binding_10 PF13460.1 EIE88711.1 - 5.7e-15 55.7 0.0 7.7e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EIE88711.1 - 1.9e-13 50.2 0.0 3.1e-08 33.1 0.0 2.1 2 0 0 2 2 2 2 NmrA-like family TrkA_N PF02254.13 EIE88711.1 - 0.00027 20.9 0.0 0.00056 19.8 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain Epimerase PF01370.16 EIE88711.1 - 0.00076 18.9 0.0 0.0014 18.0 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_2 PF03446.10 EIE88711.1 - 0.0028 17.5 0.0 0.0045 16.8 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EIE88711.1 - 0.007 16.7 0.0 0.036 14.4 0.0 2.2 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.14 EIE88711.1 - 0.028 13.1 0.0 0.12 11.1 0.0 1.9 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EIE88711.1 - 0.031 14.2 0.0 0.058 13.3 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase NAD_binding_7 PF13241.1 EIE88711.1 - 0.045 14.0 0.0 0.13 12.5 0.0 1.7 2 0 0 2 2 2 0 Putative NAD(P)-binding Semialdhyde_dh PF01118.19 EIE88711.1 - 0.067 13.4 0.3 0.23 11.7 0.1 2.2 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain MMS19_N PF14500.1 EIE88712.1 - 2e-68 230.5 4.8 1.1e-65 221.5 0.8 2.9 3 0 0 3 3 3 2 Dos2-interacting transcription regulator of RNA-Pol-II DUF2683 PF10884.3 EIE88712.1 - 0.0061 16.4 0.2 3.7 7.5 0.0 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF2683) ATP-cone PF03477.11 EIE88712.1 - 0.014 15.7 0.1 20 5.6 0.0 3.9 3 1 1 4 4 4 0 ATP cone domain DnaJ-X PF14308.1 EIE88712.1 - 0.093 11.9 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 X-domain of DnaJ-containing Pkinase PF00069.20 EIE88714.1 - 7.6e-74 248.1 0.0 1.4e-73 247.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE88714.1 - 7.5e-38 130.0 0.0 1.1e-37 129.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIE88714.1 - 1.7e-06 27.9 0.2 0.0013 18.4 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EIE88714.1 - 0.0086 15.0 0.0 0.28 10.1 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Choline_kinase PF01633.15 EIE88714.1 - 0.022 14.3 0.1 0.053 13.0 0.1 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.9 EIE88714.1 - 0.046 12.7 0.0 0.092 11.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-CCHC PF00098.18 EIE88716.1 - 0.0012 18.6 2.8 0.0012 18.6 1.9 3.1 3 0 0 3 3 3 1 Zinc knuckle zf-CCHC_6 PF15288.1 EIE88716.1 - 0.0016 18.0 5.4 0.0022 17.5 2.1 2.3 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.1 EIE88716.1 - 0.049 13.3 2.4 0.049 13.3 1.7 2.2 1 1 1 2 2 2 0 Zinc knuckle Cytochrome_C554 PF13435.1 EIE88716.1 - 0.15 12.1 6.1 0.37 10.8 4.2 1.7 1 0 0 1 1 1 0 Cytochrome c554 and c-prime RVT_1 PF00078.22 EIE88717.1 - 1.7e-31 109.2 0.1 2.7e-31 108.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.1 EIE88717.1 - 0.0061 16.8 0.2 0.016 15.4 0.2 1.7 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase RVT_1 PF00078.22 EIE88718.1 - 2.7e-33 115.1 0.0 4.7e-33 114.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EIE88718.1 - 3.3e-11 42.8 0.9 3.3e-11 42.8 0.6 2.3 2 1 1 3 3 3 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EIE88718.1 - 2.8e-10 40.5 2.0 2.8e-10 40.5 1.4 2.0 3 0 0 3 3 3 1 Endonuclease/Exonuclease/phosphatase family Egg_lysin PF01303.12 EIE88718.1 - 0.055 13.4 0.8 0.14 12.1 0.5 1.6 1 0 0 1 1 1 0 Egg lysin (Sperm-lysin) zf-CCHC PF00098.18 EIE88719.1 - 3.1e-07 29.9 10.4 0.00013 21.6 0.8 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 EIE88719.1 - 3.3e-05 23.4 2.5 0.07 12.8 0.2 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.1 EIE88719.1 - 0.0032 16.9 4.2 0.0071 15.8 0.7 2.4 1 1 1 2 2 2 1 Zinc knuckle zf-CCHC_6 PF15288.1 EIE88719.1 - 0.0076 15.8 11.7 0.11 12.1 2.8 2.6 1 1 1 2 2 2 2 Zinc knuckle RRM_1 PF00076.17 EIE88719.1 - 0.044 13.4 0.0 0.32 10.6 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE88719.1 - 0.11 12.4 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Cmc1 PF08583.5 EIE88719.1 - 0.23 11.2 5.0 0.43 10.3 3.5 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like HTH_29 PF13551.1 EIE88720.1 - 2e-10 40.8 0.1 3.3e-10 40.0 0.0 1.4 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.1 EIE88720.1 - 4.7e-08 33.7 0.2 1e-07 32.6 0.0 1.6 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.13 EIE88720.1 - 0.00021 21.2 0.1 0.0004 20.3 0.0 1.5 1 0 0 1 1 1 1 Transposase HTH_28 PF13518.1 EIE88720.1 - 0.027 14.4 0.3 0.9 9.6 0.0 2.9 3 1 0 3 3 3 0 Helix-turn-helix domain DDE_3 PF13358.1 EIE88720.1 - 0.075 12.7 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 DDE superfamily endonuclease Exo_endo_phos PF03372.18 EIE88721.1 - 5.1e-10 39.7 0.0 1.7e-09 37.9 0.0 1.8 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EIE88721.1 - 2.2e-05 24.0 0.0 5.3e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase zf-CCHC PF00098.18 EIE88722.1 - 0.043 13.7 1.8 0.043 13.7 1.3 1.9 2 0 0 2 2 2 0 Zinc knuckle FYRC PF05965.9 EIE88723.1 - 3.4e-16 58.8 0.0 7.9e-16 57.6 0.0 1.6 1 0 0 1 1 1 1 F/Y rich C-terminus FYRN PF05964.9 EIE88723.1 - 1.2e-11 43.8 0.6 1.6e-10 40.2 0.1 2.8 2 1 0 2 2 2 1 F/Y-rich N-terminus XRN_N PF03159.13 EIE88724.1 - 0.027 13.8 0.8 0.034 13.5 0.6 1.1 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus UCR_hinge PF02320.11 EIE88725.1 - 3.4e-20 71.7 6.2 5.7e-20 71.0 4.3 1.4 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein Sigma70_ner PF04546.8 EIE88725.1 - 0.0042 16.7 3.2 0.0048 16.5 2.2 1.0 1 0 0 1 1 1 1 Sigma-70, non-essential region DUF3391 PF11871.3 EIE88725.1 - 0.0071 16.5 0.7 0.0082 16.3 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3391) zf-TAZ PF02135.11 EIE88725.1 - 0.1 12.6 3.0 0.13 12.2 2.1 1.2 1 0 0 1 1 1 0 TAZ zinc finger DUF2052 PF09747.4 EIE88725.1 - 0.12 12.2 5.0 0.14 12.0 3.4 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF3484 PF11983.3 EIE88725.1 - 0.15 12.9 2.4 0.23 12.3 1.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3484) UPF0203 PF05254.7 EIE88725.1 - 1.4 8.7 8.3 15 5.4 5.8 2.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) TFIIF_alpha PF05793.7 EIE88725.1 - 2.8 6.2 6.4 3.2 6.0 4.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Adeno_terminal PF02459.10 EIE88725.1 - 3.2 5.7 7.0 3.4 5.7 4.9 1.0 1 0 0 1 1 1 0 Adenoviral DNA terminal protein EF_assoc_2 PF08356.7 EIE88726.1 - 4.3e-34 116.1 0.0 9.7e-34 115.0 0.0 1.6 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.7 EIE88726.1 - 7.5e-32 108.4 0.7 1.3e-31 107.6 0.5 1.4 1 0 0 1 1 1 1 EF hand associated Miro PF08477.8 EIE88726.1 - 2e-30 105.7 0.1 9.2e-16 58.4 0.0 2.4 2 0 0 2 2 2 2 Miro-like protein Ras PF00071.17 EIE88726.1 - 2.7e-22 78.8 0.2 1.3e-11 44.1 0.0 2.3 2 0 0 2 2 2 2 Ras family EF-hand_1 PF00036.27 EIE88726.1 - 6.1e-08 31.4 3.3 0.0015 17.6 0.2 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 EIE88726.1 - 5.6e-07 28.9 1.5 0.0047 16.7 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 EIE88726.1 - 1.5e-06 28.1 0.2 0.077 13.1 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EIE88726.1 - 7.5e-06 25.0 6.6 0.00063 18.9 0.4 2.6 2 0 0 2 2 2 2 EF hand MMR_HSR1 PF01926.18 EIE88726.1 - 2.6e-05 24.1 0.0 0.0003 20.7 0.0 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase EF-hand_8 PF13833.1 EIE88726.1 - 0.00022 20.7 1.5 0.26 10.9 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain pair AAA_22 PF13401.1 EIE88726.1 - 0.00065 19.8 0.0 0.018 15.2 0.0 2.7 2 1 0 2 2 2 1 AAA domain EF-hand_10 PF14788.1 EIE88726.1 - 0.001 18.6 5.1 0.012 15.2 0.2 2.8 3 0 0 3 3 3 1 EF hand AAA PF00004.24 EIE88726.1 - 0.0049 17.0 0.0 0.0092 16.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EIE88726.1 - 0.006 16.5 0.0 0.016 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain Dynamin_N PF00350.18 EIE88726.1 - 0.0097 15.7 0.1 0.031 14.0 0.0 1.8 1 1 1 2 2 2 1 Dynamin family Viral_helicase1 PF01443.13 EIE88726.1 - 0.022 14.2 0.0 0.041 13.3 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Arch_ATPase PF01637.13 EIE88726.1 - 0.028 14.1 0.0 0.047 13.3 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase SPARC_Ca_bdg PF10591.4 EIE88726.1 - 0.041 13.9 0.1 1 9.4 0.1 2.5 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region AAA_28 PF13521.1 EIE88726.1 - 0.043 13.7 0.0 0.097 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EIE88726.1 - 0.056 14.2 0.0 0.16 12.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EIE88726.1 - 0.075 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_24 PF13479.1 EIE88726.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 EIE88726.1 - 0.11 11.9 0.0 0.31 10.4 0.0 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 EIE88726.1 - 0.13 11.6 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family UQ_con PF00179.21 EIE88727.1 - 6.9e-35 119.5 0.1 8.5e-35 119.2 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DDE_3 PF13358.1 EIE88728.1 - 0.001 18.8 0.2 0.0027 17.4 0.1 1.9 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE88728.1 - 0.017 15.2 0.1 0.29 11.2 0.0 2.8 2 0 0 2 2 2 0 Transposase Vsr PF03852.10 EIE88728.1 - 0.044 13.4 0.0 0.14 11.7 0.0 1.9 1 0 0 1 1 1 0 DNA mismatch endonuclease Vsr NST1 PF13945.1 EIE88729.1 - 4e-46 157.4 13.7 4e-46 157.4 9.5 3.9 2 1 2 4 4 4 1 Salt tolerance down-regulator CUE PF02845.11 EIE88730.1 - 4e-08 32.5 0.1 9.2e-08 31.4 0.0 1.6 1 0 0 1 1 1 1 CUE domain DUF1296 PF06972.6 EIE88730.1 - 0.036 14.0 0.0 0.094 12.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) PIF1 PF05970.9 EIE88731.1 - 3.3e-30 105.2 0.1 3.1e-23 82.3 0.1 2.4 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 EIE88731.1 - 4.9e-19 68.6 0.0 8.4e-19 67.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 EIE88731.1 - 5.8e-10 39.0 0.1 6.7e-07 29.0 0.0 2.5 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase Herpes_Helicase PF02689.9 EIE88731.1 - 7.8e-06 23.9 0.3 0.0047 14.7 0.0 2.1 2 0 0 2 2 2 2 Helicase AAA_19 PF13245.1 EIE88731.1 - 8.2e-06 25.4 0.0 2.1e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain ABC_tran PF00005.22 EIE88731.1 - 0.00012 22.3 0.1 0.00033 20.9 0.1 1.9 1 1 0 1 1 1 1 ABC transporter AAA_22 PF13401.1 EIE88731.1 - 0.00019 21.5 0.0 0.0004 20.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EIE88731.1 - 0.0014 19.4 0.0 0.0033 18.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 EIE88731.1 - 0.0015 18.6 0.1 0.0077 16.3 0.0 2.1 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_14 PF13173.1 EIE88731.1 - 0.0037 17.1 0.0 0.0093 15.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain Helicase_RecD PF05127.9 EIE88731.1 - 0.0065 16.1 0.2 0.1 12.2 0.1 2.3 1 1 0 1 1 1 1 Helicase AAA_16 PF13191.1 EIE88731.1 - 0.007 16.3 0.0 0.013 15.4 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 EIE88731.1 - 0.011 15.4 0.1 0.032 13.8 0.1 1.9 1 1 0 1 1 1 0 NACHT domain KAP_NTPase PF07693.9 EIE88731.1 - 0.018 14.0 0.0 0.022 13.7 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain AAA_28 PF13521.1 EIE88731.1 - 0.02 14.8 0.1 0.044 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EIE88731.1 - 0.023 13.9 0.1 0.071 12.3 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein DUF258 PF03193.11 EIE88731.1 - 0.03 13.4 0.0 0.049 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Sigma54_activat PF00158.21 EIE88731.1 - 0.046 13.2 0.0 0.084 12.3 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain UPF0079 PF02367.12 EIE88731.1 - 0.051 13.1 0.2 0.33 10.5 0.0 2.2 1 1 1 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Sigma54_activ_2 PF14532.1 EIE88731.1 - 0.078 13.0 0.1 0.22 11.5 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA PF00004.24 EIE88731.1 - 0.12 12.5 0.0 0.47 10.6 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 EIE88731.1 - 0.14 11.1 0.1 0.4 9.6 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DDE_3 PF13358.1 EIE88736.1 - 4.3e-17 62.2 0.6 1.2e-16 60.7 0.1 2.0 3 0 0 3 3 3 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE88736.1 - 2.7e-10 40.1 0.3 6.5e-10 38.9 0.2 1.7 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.1 EIE88736.1 - 0.043 13.9 0.0 0.12 12.5 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn helix RVT_1 PF00078.22 EIE88737.1 - 7e-23 81.0 0.0 1.1e-22 80.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EIE88737.1 - 2.1e-05 24.0 0.0 5.8e-05 22.6 0.0 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase TPR_MLP1_2 PF07926.7 EIE88738.1 - 0.00012 21.7 0.4 0.00019 21.1 0.3 1.2 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein Phage_GP20 PF06810.6 EIE88738.1 - 0.00028 20.3 0.3 0.0004 19.8 0.2 1.2 1 0 0 1 1 1 1 Phage minor structural protein GP20 Med4 PF10018.4 EIE88738.1 - 0.00082 18.8 0.1 0.0011 18.3 0.1 1.2 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 DUF972 PF06156.8 EIE88738.1 - 0.0086 16.4 0.6 0.015 15.6 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF972) DivIVA PF05103.8 EIE88738.1 - 0.017 15.2 0.2 0.027 14.5 0.1 1.4 1 0 0 1 1 1 0 DivIVA protein Cluap1 PF10234.4 EIE88738.1 - 0.019 14.1 0.2 0.027 13.6 0.2 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 DivIC PF04977.10 EIE88738.1 - 0.033 13.6 0.2 0.064 12.7 0.1 1.5 1 0 0 1 1 1 0 Septum formation initiator HALZ PF02183.13 EIE88738.1 - 0.04 13.6 1.5 0.1 12.3 1.1 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper Mito_fiss_reg PF05308.6 EIE88738.1 - 0.042 13.2 1.0 0.06 12.6 0.7 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator SlyX PF04102.7 EIE88738.1 - 0.044 14.1 0.4 0.12 12.7 0.3 1.8 1 0 0 1 1 1 0 SlyX MAD PF05557.8 EIE88738.1 - 0.065 11.3 0.8 0.098 10.7 0.6 1.2 1 0 0 1 1 1 0 Mitotic checkpoint protein Rogdi_lz PF10259.4 EIE88738.1 - 0.067 12.2 1.5 0.1 11.6 1.0 1.2 1 0 0 1 1 1 0 Rogdi leucine zipper containing protein DUF1875 PF08961.5 EIE88738.1 - 0.093 12.0 0.1 0.14 11.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1875) Baculo_PEP_C PF04513.7 EIE88738.1 - 0.13 12.0 9.5 0.24 11.2 6.6 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 EIE88738.1 - 0.57 9.3 6.3 0.79 8.8 4.4 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein rve PF00665.21 EIE88739.1 - 1.8e-22 79.7 0.0 4.3e-22 78.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE88739.1 - 8.1e-15 54.7 0.1 1.6e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.12 EIE88739.1 - 7.8e-09 35.4 0.1 2.2e-08 34.0 0.1 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein Chromo PF00385.19 EIE88739.1 - 4e-08 32.8 0.1 9.3e-08 31.6 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 EIE88739.1 - 0.00048 19.4 1.6 0.0014 17.9 1.1 1.9 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Tudor-knot PF11717.3 EIE88739.1 - 0.11 12.2 0.2 0.31 10.7 0.1 1.7 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain Transposase_21 PF02992.9 EIE88740.1 - 1.9e-21 76.2 0.0 3.3e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DUF1258 PF06869.7 EIE88740.1 - 0.007 15.4 0.0 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) DUF3373 PF11853.3 EIE88741.1 - 0.072 11.6 1.0 0.087 11.3 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) TSA PF03249.8 EIE88741.1 - 0.089 11.3 4.3 0.11 10.9 3.0 1.1 1 0 0 1 1 1 0 Type specific antigen LAG1-DNAbind PF09271.6 EIE88741.1 - 0.22 12.0 3.3 0.27 11.7 1.8 1.5 1 1 0 1 1 1 0 LAG1, DNA binding DUF2140 PF09911.4 EIE88741.1 - 0.29 10.2 2.1 0.47 9.6 1.5 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) DDE_3 PF13358.1 EIE88742.1 - 5.1e-14 52.2 0.6 7.2e-14 51.7 0.3 1.4 1 1 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE88742.1 - 0.0024 17.9 0.1 0.0056 16.7 0.0 1.6 2 0 0 2 2 2 1 Integrase core domain DDE_3 PF13358.1 EIE88745.1 - 2.8e-10 40.1 0.1 4.6e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-trcl PF13451.1 EIE88745.1 - 1.4 8.6 4.9 0.62 9.7 0.3 2.2 2 0 0 2 2 2 0 Probable zinc-binding domain HTH_Tnp_Tc3_2 PF01498.13 EIE88746.1 - 8e-08 32.2 0.5 2.9e-07 30.4 0.1 2.2 2 0 0 2 2 2 1 Transposase GTP_EFTU_D2 PF03144.20 EIE88746.1 - 0.015 15.4 0.2 0.12 12.5 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu domain 2 DDE_3 PF13358.1 EIE88746.1 - 0.054 13.2 0.0 0.093 12.4 0.0 1.4 1 0 0 1 1 1 0 DDE superfamily endonuclease DUF1582 PF07621.6 EIE88747.1 - 0.92 9.6 3.9 0.38 10.8 0.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1582) PBP PF01161.15 EIE88749.1 - 2.7e-31 108.3 0.8 3.4e-31 108.0 0.5 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Ribosomal_S6e PF01092.14 EIE88750.1 - 5.2e-48 161.8 0.3 5.2e-48 161.8 0.2 2.1 2 0 0 2 2 2 1 Ribosomal protein S6e YpjP PF14005.1 EIE88750.1 - 0.12 12.1 0.4 4.3 7.1 0.0 2.1 2 0 0 2 2 2 0 YpjP-like protein IF4E PF01652.13 EIE88751.1 - 2.6e-57 192.9 1.3 3.1e-57 192.6 0.9 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Ras PF00071.17 EIE88752.1 - 5.7e-59 198.1 0.1 6.8e-59 197.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIE88752.1 - 5.5e-21 75.2 0.0 8.9e-21 74.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIE88752.1 - 9.9e-08 31.4 0.0 1.2e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EIE88752.1 - 4.3e-05 23.0 0.0 0.00014 21.3 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EIE88752.1 - 0.00099 19.0 0.0 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EIE88752.1 - 0.092 11.9 0.1 0.16 11.1 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function, DUF258 IstB_IS21 PF01695.12 EIE88752.1 - 0.16 11.3 0.2 0.46 9.8 0.1 1.8 1 1 1 2 2 2 0 IstB-like ATP binding protein Actin PF00022.14 EIE88753.1 - 4.4e-85 285.4 0.0 6e-85 285.0 0.0 1.1 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EIE88753.1 - 3.3e-05 22.6 0.0 0.16 10.5 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Robl_LC7 PF03259.12 EIE88753.1 - 0.076 12.5 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Roadblock/LC7 domain PA26 PF04636.8 EIE88754.1 - 9.7e-79 265.1 0.0 1.5e-78 264.4 0.0 1.2 1 0 0 1 1 1 1 PA26 p53-induced protein (sestrin) DUF4458 PF14660.1 EIE88755.1 - 0.0025 17.8 0.2 0.0025 17.8 0.2 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF4458) Shikimate_dh_N PF08501.6 EIE88755.1 - 0.013 15.5 0.2 0.093 12.7 0.0 2.4 3 0 0 3 3 3 0 Shikimate dehydrogenase substrate binding domain GPI-anchored PF10342.4 EIE88755.1 - 1 9.9 9.1 0.81 10.2 1.0 2.4 2 0 0 2 2 2 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family SKIP_SNW PF02731.10 EIE88756.1 - 1.7e-64 216.0 1.0 1.7e-64 216.0 0.7 2.4 2 0 0 2 2 2 1 SKIP/SNW domain Abhydrolase_9_N PF15420.1 EIE88758.1 - 0.085 12.6 0.4 0.085 12.6 0.3 2.0 2 1 1 3 3 3 0 Alpha/beta-hydrolase family N-terminus CbiQ PF02361.11 EIE88758.1 - 2 7.8 7.1 1.3 8.5 3.8 1.5 2 0 0 2 2 2 0 Cobalt transport protein Aminotran_4 PF01063.14 EIE88759.1 - 3e-32 111.9 0.0 4e-32 111.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV RasGEF PF00617.14 EIE88761.1 - 5.7e-42 143.5 0.3 1.1e-41 142.6 0.2 1.4 1 0 0 1 1 1 1 RasGEF domain TPR_11 PF13414.1 EIE88762.1 - 8.1e-30 102.2 9.5 3e-19 68.4 3.2 2.4 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 EIE88762.1 - 3.8e-25 86.4 10.1 1.8e-10 39.9 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EIE88762.1 - 1.2e-20 71.6 9.5 1.3e-07 31.0 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 EIE88762.1 - 1.6e-15 56.1 3.8 4.4e-05 23.7 0.0 4.0 2 1 2 4 4 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 EIE88762.1 - 8.3e-15 53.6 13.2 7.3e-08 32.0 0.2 4.1 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 EIE88762.1 - 1.6e-13 49.3 1.8 9.5e-06 25.0 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 EIE88762.1 - 5.5e-13 49.0 8.7 4.4e-07 30.1 0.4 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EIE88762.1 - 1.8e-12 47.0 3.3 1.8e-07 30.9 0.8 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 EIE88762.1 - 4.5e-11 41.7 5.8 0.00069 19.2 0.2 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EIE88762.1 - 8.6e-11 42.2 6.8 9.8e-07 29.2 2.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 EIE88762.1 - 5.3e-09 36.1 5.1 5.4e-09 36.0 2.2 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EIE88762.1 - 0.00011 21.9 0.6 0.00081 19.1 0.1 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_15 PF13429.1 EIE88762.1 - 0.00013 21.1 3.3 0.0027 16.7 0.7 3.0 1 1 0 2 2 2 1 Tetratricopeptide repeat BTAD PF03704.12 EIE88762.1 - 0.0013 19.0 0.4 0.018 15.3 0.3 2.2 1 1 0 1 1 1 1 Bacterial transcriptional activator domain TPR_10 PF13374.1 EIE88762.1 - 0.0039 17.0 1.3 0.75 9.8 0.2 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat MIT PF04212.13 EIE88762.1 - 0.0061 16.4 8.5 0.12 12.2 0.5 3.6 2 2 1 3 3 3 3 MIT (microtubule interacting and transport) domain NARP1 PF12569.3 EIE88762.1 - 0.0084 14.9 4.9 0.086 11.5 1.6 2.5 1 1 1 2 2 2 1 NMDA receptor-regulated protein 1 TPR_6 PF13174.1 EIE88762.1 - 0.015 15.7 6.0 2.5 8.7 0.5 4.0 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 EIE88762.1 - 0.028 14.8 0.1 0.24 11.9 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_20 PF14561.1 EIE88762.1 - 0.12 12.4 7.7 0.074 13.1 1.0 3.3 1 1 1 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EIE88762.1 - 0.25 11.2 1.4 13 5.7 0.1 3.3 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat PPR PF01535.15 EIE88762.1 - 0.67 10.0 3.5 47 4.2 0.1 3.9 4 0 0 4 4 3 0 PPR repeat HgmA PF04209.8 EIE88763.1 - 5e-191 634.6 0.0 5.6e-191 634.4 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase HTH_15 PF12324.3 EIE88764.1 - 0.06 13.0 0.1 0.14 11.8 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of alkylmercury lyase KapB PF08810.5 EIE88764.1 - 0.14 12.2 1.4 0.28 11.2 0.9 1.5 1 0 0 1 1 1 0 Kinase associated protein B MAS20 PF02064.10 EIE88764.1 - 0.73 9.7 7.9 2 8.3 0.7 2.4 1 1 0 2 2 2 0 MAS20 protein import receptor Yippee-Mis18 PF03226.9 EIE88766.1 - 6.2e-08 32.5 0.9 3.2e-06 27.1 0.1 2.1 1 1 1 2 2 2 2 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Pga1 PF10333.4 EIE88767.1 - 0.074 12.7 2.1 2.6 7.6 1.5 2.3 1 1 0 1 1 1 0 GPI-Mannosyltransferase II co-activator Ribosomal_S8e PF01201.17 EIE88768.1 - 7.5e-39 132.8 0.1 9.7e-39 132.5 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e ERG4_ERG24 PF01222.12 EIE88769.1 - 4.9e-108 361.4 6.4 6.1e-108 361.1 4.4 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF2207 PF09972.4 EIE88769.1 - 0.038 12.5 0.1 0.098 11.2 0.0 1.8 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) DPPIV_N PF00930.16 EIE88770.1 - 3.9e-72 242.7 13.6 2.2e-60 204.1 5.1 2.1 1 1 1 2 2 2 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 EIE88770.1 - 5.6e-38 130.2 1.0 1.2e-37 129.1 0.7 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EIE88770.1 - 2.3e-10 40.4 0.0 4.1e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIE88770.1 - 1.3e-07 31.7 0.0 2.3e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EIE88770.1 - 2.9e-06 26.9 1.3 7.5e-06 25.5 0.7 1.7 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.7 EIE88770.1 - 0.0058 15.1 0.0 0.097 11.1 0.0 2.2 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.8 EIE88770.1 - 0.088 12.3 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold WD40 PF00400.27 EIE88771.1 - 1.9e-31 106.7 10.3 1.2e-09 37.6 0.0 6.8 7 0 0 7 7 7 4 WD domain, G-beta repeat Nup160 PF11715.3 EIE88771.1 - 0.0011 17.2 0.1 0.038 12.1 0.0 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Med31 PF05669.7 EIE88771.1 - 0.0034 17.0 0.4 0.0084 15.8 0.3 1.6 1 0 0 1 1 1 1 SOH1 Bromodomain PF00439.20 EIE88771.1 - 0.0049 16.7 0.0 0.014 15.2 0.0 1.7 1 0 0 1 1 1 1 Bromodomain alpha-hel2 PF14456.1 EIE88771.1 - 0.1 11.3 0.3 0.29 9.8 0.2 1.7 1 0 0 1 1 1 0 Alpha-helical domain 2 GCR1_C PF12550.3 EIE88772.1 - 5.1e-26 90.3 0.7 5.1e-25 87.1 0.2 2.6 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes RVT_1 PF00078.22 EIE88773.1 - 1.7e-18 66.7 0.0 1.9e-18 66.5 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Mito_fiss_reg PF05308.6 EIE88774.1 - 0.062 12.6 3.0 0.099 11.9 2.1 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF3573 PF12097.3 EIE88774.1 - 0.12 10.9 1.6 0.12 10.9 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3573) TMF_TATA_bd PF12325.3 EIE88774.1 - 9.2 6.0 9.7 0.11 12.2 0.7 2.4 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding DDE_1 PF03184.14 EIE88777.1 - 5.5e-26 91.0 0.5 1.3e-25 89.8 0.5 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_3 PF13358.1 EIE88777.1 - 0.014 15.1 0.1 0.033 13.9 0.0 1.7 1 1 0 1 1 1 0 DDE superfamily endonuclease DDE_1 PF03184.14 EIE88780.1 - 3.3e-26 91.7 0.6 7.7e-26 90.5 0.6 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_3 PF13358.1 EIE88780.1 - 0.014 15.1 0.1 0.033 13.9 0.0 1.7 1 1 0 1 1 1 0 DDE superfamily endonuclease Pkinase PF00069.20 EIE88784.1 - 7.8e-68 228.4 0.0 1.5e-67 227.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE88784.1 - 1.4e-30 106.2 0.0 2.1e-30 105.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIE88784.1 - 0.043 13.5 0.0 0.043 13.5 0.0 2.6 2 2 0 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EIE88784.1 - 0.065 12.0 0.1 0.13 11.0 0.1 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Tom37_C PF11801.3 EIE88784.1 - 1.2 8.9 8.3 3.2 7.5 5.7 1.7 1 1 0 1 1 1 0 Tom37 C-terminal domain RNA_pol_Rpc4 PF05132.9 EIE88784.1 - 6.9 6.6 14.1 86 3.1 9.7 2.2 1 1 0 1 1 1 0 RNA polymerase III RPC4 GAGA_bind PF06217.7 EIE88784.1 - 7.1 6.4 9.6 9.8 6.0 6.7 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family GnRH PF00446.12 EIE88785.1 - 0.15 12.1 4.3 0.34 11.0 3.0 1.6 1 0 0 1 1 1 0 Gonadotropin-releasing hormone RNase_PH PF01138.16 EIE88787.1 - 2.2e-25 89.4 0.1 3.6e-25 88.7 0.1 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EIE88787.1 - 4.2e-05 23.3 0.0 9.8e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Cas_Csd1 PF09709.5 EIE88787.1 - 0.032 12.5 0.0 0.046 12.0 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csd1) Rsbr_N PF08678.5 EIE88787.1 - 0.1 12.4 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Rsbr N terminal Y_phosphatase2 PF03162.8 EIE88788.1 - 1.5e-40 138.2 0.2 2e-20 72.8 0.0 2.0 1 1 1 2 2 2 2 Tyrosine phosphatase family Hemerythrin PF01814.18 EIE88789.1 - 0.0036 17.4 2.0 0.0072 16.4 1.4 1.5 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain MCP_N PF05581.7 EIE88789.1 - 0.18 11.9 0.6 0.58 10.3 0.1 2.1 2 1 0 2 2 2 0 Vibrio chemotaxis protein N terminus Nsp1_C PF05064.8 EIE88789.1 - 0.2 11.2 5.7 0.44 10.2 0.1 3.1 3 0 0 3 3 3 0 Nsp1-like C-terminal region IMD PF08397.6 EIE88789.1 - 0.25 10.6 7.0 0.54 9.5 4.9 1.5 1 0 0 1 1 1 0 IRSp53/MIM homology domain DUF501 PF04417.7 EIE88789.1 - 1.4 8.7 4.1 2.2 8.1 1.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF501) ING PF12998.2 EIE88789.1 - 1.7 8.9 12.0 0.83 9.9 1.8 2.9 1 1 2 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding DUF1664 PF07889.7 EIE88789.1 - 5.9 6.7 11.8 1.3 8.8 0.7 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) WD40 PF00400.27 EIE88790.1 - 4.1e-30 102.5 1.9 1.3e-06 28.0 0.0 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 EIE88790.1 - 0.0039 16.0 2.8 2.6 6.7 0.1 3.2 1 1 3 4 4 4 2 Coatomer WD associated region Bacteriocin_IIi PF11758.3 EIE88790.1 - 0.52 9.9 2.8 1.2 8.8 1.9 1.5 1 0 0 1 1 1 0 Aureocin-like type II bacteriocin Fungal_trans PF04082.13 EIE88792.1 - 8.7e-20 70.6 0.7 4.7e-19 68.2 0.1 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Fungal_trans PF04082.13 EIE88793.1 - 1.3e-25 89.7 0.0 2.6e-25 88.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain YyzF PF14116.1 EIE88793.1 - 0.074 13.0 0.2 0.16 11.9 0.1 1.6 1 0 0 1 1 1 0 YyzF-like protein B-block_TFIIIC PF04182.7 EIE88794.1 - 2.1e-10 40.2 3.4 2.1e-08 33.8 0.0 4.1 4 0 0 4 4 4 1 B-block binding subunit of TFIIIC PBP1_TM PF14812.1 EIE88794.1 - 2.2 8.6 18.2 8.5 6.7 12.6 2.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RasGEF PF00617.14 EIE88795.1 - 7.6e-62 208.3 2.3 1.2e-61 207.7 1.0 1.8 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 EIE88795.1 - 1.7e-27 95.5 1.5 6.8e-27 93.6 0.3 2.6 2 0 0 2 2 2 1 RasGEF N-terminal motif Serinc PF03348.10 EIE88795.1 - 0.017 13.8 1.8 0.028 13.1 1.2 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) MFS_1 PF07690.11 EIE88796.1 - 5.9e-33 114.0 16.2 5.9e-33 114.0 11.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIE88796.1 - 9.3e-05 21.1 17.2 0.00017 20.3 0.8 2.8 2 1 1 3 3 3 3 Sugar (and other) transporter DUF4131 PF13567.1 EIE88796.1 - 8.2 5.8 13.3 0.11 11.8 0.1 2.9 2 2 1 3 3 3 0 Domain of unknown function (DUF4131) DUF575 PF04746.7 EIE88797.1 - 0.078 13.0 0.4 0.16 12.0 0.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF575) Adeno_E4 PF05385.6 EIE88797.1 - 0.078 12.9 0.8 0.35 10.8 0.2 1.9 1 1 1 2 2 2 0 Mastadenovirus early E4 13 kDa protein CDC37_N PF03234.9 EIE88797.1 - 0.69 10.2 10.4 0.87 9.8 7.2 1.2 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding Kinesin PF00225.18 EIE88798.1 - 1.2e-65 221.4 0.5 1.3e-65 221.3 0.3 1.1 1 0 0 1 1 1 1 Kinesin motor domain DUF3231 PF11553.3 EIE88798.1 - 0.036 13.5 0.0 0.086 12.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3231) T2SE PF00437.15 EIE88798.1 - 0.05 12.4 0.0 0.096 11.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Penicillinase_R PF03965.11 EIE88798.1 - 0.089 12.8 0.1 0.3 11.1 0.0 1.9 2 0 0 2 2 2 0 Penicillinase repressor Sigma54_activat PF00158.21 EIE88798.1 - 0.13 11.7 0.0 0.35 10.3 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain Gemin6 PF06372.7 EIE88799.1 - 0.00017 20.9 0.0 0.00023 20.5 0.0 1.1 1 0 0 1 1 1 1 Gemin6 protein Pkinase PF00069.20 EIE88800.1 - 5.3e-62 209.3 0.0 6.4e-62 209.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE88800.1 - 6.8e-41 140.0 0.0 8.6e-41 139.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EIE88800.1 - 1.5e-06 27.6 0.3 3.1e-06 26.6 0.2 1.4 1 1 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 EIE88800.1 - 6e-06 25.4 0.0 7.6e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EIE88800.1 - 0.001 18.8 0.0 0.0016 18.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EIE88800.1 - 0.092 12.3 0.4 0.17 11.4 0.1 1.4 1 1 0 1 1 1 0 Choline/ethanolamine kinase SapB_1 PF05184.10 EIE88800.1 - 0.13 12.1 1.1 0.71 9.7 0.8 2.3 1 1 0 1 1 1 0 Saposin-like type B, region 1 Exo_endo_phos PF03372.18 EIE88801.1 - 7.4e-14 52.2 0.0 1.1e-13 51.7 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EIE88801.1 - 6.1e-11 41.9 0.0 2e-10 40.3 0.0 1.9 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase zf-GRF PF06839.7 EIE88801.1 - 1.8e-08 34.1 1.6 4.2e-08 32.9 1.1 1.7 1 0 0 1 1 1 1 GRF zinc finger Kinesin PF00225.18 EIE88802.1 - 5.1e-95 318.0 0.0 5.1e-95 318.0 0.0 2.0 2 0 0 2 2 2 1 Kinesin motor domain zf-C2H2 PF00096.21 EIE88803.1 - 1.6e-11 43.7 11.1 6.5e-06 26.1 2.8 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIE88803.1 - 5.7e-11 42.1 15.8 8.4e-08 32.1 1.0 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EIE88803.1 - 4e-10 39.3 10.0 4.4e-05 23.5 2.9 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 EIE88803.1 - 0.00039 20.5 3.6 0.11 12.7 0.3 2.3 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EIE88803.1 - 0.016 15.3 4.8 0.39 10.9 0.6 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.13 EIE88803.1 - 0.024 14.9 1.8 0.036 14.4 1.2 1.3 1 0 0 1 1 1 0 TRAF-type zinc finger zf-C2H2_2 PF12756.2 EIE88803.1 - 0.23 11.5 3.2 1.2 9.2 0.3 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Ras PF00071.17 EIE88804.1 - 4.8e-54 182.1 0.0 5.5e-54 181.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIE88804.1 - 6.6e-17 62.1 0.0 9.1e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIE88804.1 - 1.7e-10 40.4 0.0 2.1e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EIE88804.1 - 0.0022 17.1 0.0 0.0028 16.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EIE88804.1 - 0.0025 17.2 0.0 0.013 14.8 0.0 1.8 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EIE88804.1 - 0.0026 16.9 0.0 0.004 16.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EIE88804.1 - 0.0048 16.8 0.0 0.0067 16.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 EIE88804.1 - 0.017 14.5 0.0 0.25 10.8 0.0 2.2 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation RRM_1 PF00076.17 EIE88805.1 - 9.7e-36 121.2 0.0 3e-21 74.8 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE88805.1 - 1.9e-24 85.4 0.2 1.7e-14 53.5 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE88805.1 - 3.9e-21 74.6 0.0 5.3e-10 39.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EIE88805.1 - 0.00082 19.0 0.1 1.5 8.6 0.0 2.6 2 1 1 3 3 3 2 Nup53/35/40-type RNA recognition motif WD40 PF00400.27 EIE88806.1 - 1e-07 31.5 0.1 3.5e-06 26.6 0.0 2.5 2 0 0 2 2 2 1 WD domain, G-beta repeat EcoRI_methylase PF13651.1 EIE88806.1 - 0.0059 15.7 0.4 0.01 14.9 0.2 1.3 1 1 0 1 1 1 1 Adenine-specific methyltransferase EcoRI DUF1319 PF07028.6 EIE88806.1 - 0.019 15.1 0.6 0.043 14.0 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1319) FlgD_ig PF13860.1 EIE88806.1 - 0.021 14.5 0.0 0.042 13.5 0.0 1.4 1 0 0 1 1 1 0 FlgD Ig-like domain Mgr1 PF08602.5 EIE88806.1 - 0.038 12.9 0.5 0.053 12.5 0.4 1.1 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit eIF2A PF08662.6 EIE88806.1 - 0.068 12.8 0.6 1.3 8.7 0.0 2.7 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A Atg14 PF10186.4 EIE88806.1 - 0.35 9.7 4.2 0.51 9.2 2.9 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 CaM_binding PF07839.6 EIE88806.1 - 0.39 10.9 5.3 0.34 11.1 2.4 1.8 2 1 0 2 2 2 0 Plant calmodulin-binding domain ABC_tran_2 PF12848.2 EIE88806.1 - 0.98 9.3 4.7 2 8.2 2.6 1.9 1 1 1 2 2 2 0 ABC transporter PseudoU_synth_1 PF01416.15 EIE88808.1 - 8.1e-15 55.1 0.0 3.3e-13 49.9 0.0 3.0 3 0 0 3 3 3 1 tRNA pseudouridine synthase Flu_NS2 PF00601.14 EIE88808.1 - 0.057 13.6 1.8 0.15 12.2 0.8 2.2 1 1 0 1 1 1 0 Influenza non-structural protein (NS2) Kinesin PF00225.18 EIE88808.1 - 0.058 12.0 4.0 0.11 11.1 2.8 1.4 1 0 0 1 1 1 0 Kinesin motor domain Spore_coat_CotO PF14153.1 EIE88808.1 - 0.19 11.1 12.2 0.37 10.2 8.4 1.4 1 0 0 1 1 1 0 Spore coat protein CotO Histone PF00125.19 EIE88809.1 - 9.3e-32 108.9 0.4 1.4e-31 108.3 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EIE88809.1 - 7.3e-06 26.0 0.0 1.1e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EIE88809.1 - 0.0015 18.5 0.1 0.0029 17.6 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EIE88809.1 - 0.0035 17.0 0.1 0.0064 16.1 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated CENP-T PF15511.1 EIE88809.1 - 0.14 11.3 1.3 0.29 10.3 0.9 1.6 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T AA_kinase PF00696.23 EIE88810.1 - 1.3e-27 96.9 0.0 1.7e-27 96.4 0.0 1.2 1 0 0 1 1 1 1 Amino acid kinase family ACT PF01842.20 EIE88810.1 - 2.8e-05 23.4 0.2 0.00014 21.2 0.0 2.2 2 1 0 2 2 2 1 ACT domain ACT_7 PF13840.1 EIE88810.1 - 0.027 13.9 0.1 0.06 12.8 0.0 1.6 1 0 0 1 1 1 0 ACT domain MFS_1 PF07690.11 EIE88811.1 - 7.8e-09 34.7 18.1 2.5e-06 26.4 4.3 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.1 EIE88811.1 - 0.0011 17.4 0.0 0.0011 17.4 0.0 2.5 1 1 1 2 2 2 1 MFS/sugar transport protein MFS_1_like PF12832.2 EIE88811.1 - 0.3 10.9 4.5 4.1 7.2 0.0 2.9 3 0 0 3 3 3 0 MFS_1 like family Sugar_tr PF00083.19 EIE88811.1 - 2.9 6.3 12.8 0.79 8.2 0.4 2.7 3 0 0 3 3 3 0 Sugar (and other) transporter DUF1972 PF09314.6 EIE88812.1 - 0.075 12.4 0.5 0.13 11.7 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1972) CH PF00307.26 EIE88813.1 - 1.1e-23 83.3 2.3 1.7e-10 40.9 0.0 4.3 4 0 0 4 4 4 2 Calponin homology (CH) domain GAS2 PF02187.12 EIE88813.1 - 4.3e-08 32.8 0.2 1.5e-07 31.0 0.2 1.9 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain CAMSAP_CH PF11971.3 EIE88813.1 - 3.6e-07 29.7 0.5 4.2e-05 23.1 0.0 3.7 3 0 0 3 3 3 1 CAMSAP CH domain PH PF00169.24 EIE88814.1 - 1.2e-05 25.4 0.0 1.2e-05 25.4 0.0 2.0 2 1 0 2 2 2 1 PH domain Cofilin_ADF PF00241.15 EIE88814.1 - 1.6e-05 24.8 1.2 0.00014 21.7 0.0 2.3 2 0 0 2 2 2 1 Cofilin/tropomyosin-type actin-binding protein PH_11 PF15413.1 EIE88814.1 - 0.099 12.9 3.6 0.72 10.1 0.1 2.9 2 1 0 2 2 2 0 Pleckstrin homology domain APG6 PF04111.7 EIE88814.1 - 2.6 7.0 14.2 4.5 6.2 9.8 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Mg_trans_NIPA PF05653.9 EIE88815.1 - 2e-79 266.6 25.0 2.4e-79 266.4 17.3 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.15 EIE88815.1 - 5.8e-06 26.3 7.3 5.8e-06 26.3 5.1 3.4 2 1 1 3 3 3 1 EamA-like transporter family EmrE PF13536.1 EIE88815.1 - 2.7e-05 24.3 7.2 2.7e-05 24.3 5.0 3.2 2 1 1 3 3 3 1 Multidrug resistance efflux transporter DUF1482 PF07358.6 EIE88817.1 - 0.04 13.5 0.0 0.075 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1482) DUF1643 PF07799.7 EIE88817.1 - 0.055 13.1 0.1 0.082 12.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1643) Prok-E2_B PF14461.1 EIE88817.1 - 0.097 12.4 0.1 0.32 10.7 0.0 1.8 2 0 0 2 2 2 0 Prokaryotic E2 family B DUF2358 PF10184.4 EIE88818.1 - 0.023 14.5 0.0 2.3 8.1 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2358) FIST PF08495.5 EIE88819.1 - 1e-05 24.7 0.0 2.1e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 FIST N domain DEAD PF00270.24 EIE88820.1 - 1.9e-41 141.4 0.0 3.7e-41 140.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIE88820.1 - 2e-21 75.6 0.0 4.6e-21 74.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EIE88820.1 - 1.6e-18 65.9 0.1 4e-18 64.7 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 EIE88820.1 - 0.00086 19.1 7.7 0.0014 18.5 0.0 3.5 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EIE88820.1 - 0.083 13.0 0.6 0.91 9.6 0.4 2.7 1 1 0 1 1 1 0 AAA domain Sugar_tr PF00083.19 EIE88821.1 - 4.5e-29 101.3 0.7 5.4e-29 101.0 0.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIE88821.1 - 4.8e-07 28.8 1.3 6.1e-07 28.4 0.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 EIE88821.1 - 0.0084 14.5 3.3 0.0088 14.4 0.0 1.9 1 1 0 2 2 2 1 MFS/sugar transport protein DUF1616 PF07760.6 EIE88821.1 - 0.057 12.5 0.9 0.068 12.2 0.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1616) Oxidored_q5_N PF01059.12 EIE88821.1 - 0.083 12.7 5.4 0.67 9.8 0.4 2.4 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase chain 4, amino terminus YkuI_C PF10388.4 EIE88821.1 - 0.26 10.9 2.6 0.35 10.5 0.5 1.8 2 0 0 2 2 2 0 EAL-domain associated signalling protein domain DUF2269 PF10027.4 EIE88821.1 - 1.7 8.4 4.9 4.6 7.0 0.0 2.3 1 1 0 2 2 2 0 Predicted integral membrane protein (DUF2269) NADH_dehy_S2_C PF06444.6 EIE88821.1 - 5.5 7.3 7.5 0.38 11.1 0.9 2.2 3 0 0 3 3 3 0 NADH dehydrogenase subunit 2 C-terminus zf-Tim10_DDP PF02953.10 EIE88822.1 - 4.5 6.6 8.4 22 4.4 5.9 1.8 1 1 0 1 1 1 0 Tim10/DDP family zinc finger ASL_C PF08328.6 EIE88823.1 - 0.038 13.8 0.1 0.048 13.5 0.1 1.2 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminal zf-Tim10_DDP PF02953.10 EIE88824.1 - 4.5 6.6 8.4 22 4.4 5.9 1.8 1 1 0 1 1 1 0 Tim10/DDP family zinc finger RicinB_lectin_2 PF14200.1 EIE88825.1 - 6.1e-05 23.3 2.2 0.0026 18.1 1.8 2.2 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 EIE88825.1 - 8e-05 22.6 1.7 0.00013 21.9 1.2 1.6 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain PPO1_DWL PF12142.3 EIE88825.1 - 0.0041 16.6 2.3 0.05 13.1 0.4 2.8 1 1 2 3 3 3 1 Polyphenol oxidase middle domain ERM PF00769.14 EIE88826.1 - 0.0016 18.0 26.2 0.0016 18.0 18.2 3.3 1 1 2 3 3 3 1 Ezrin/radixin/moesin family Beta-Casp PF10996.3 EIE88827.1 - 1e-08 35.1 0.0 3.1e-08 33.5 0.0 1.8 1 1 1 2 2 2 1 Beta-Casp domain Nop10p PF04135.7 EIE88828.1 - 2.9e-22 78.1 0.4 3.5e-22 77.8 0.3 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family Ribosomal_60s PF00428.14 EIE88829.1 - 5.6e-26 90.7 7.9 6.8e-26 90.4 5.4 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Anti-adapt_IraP PF10796.4 EIE88830.1 - 0.089 13.1 0.0 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 Sigma-S stabilisation anti-adaptor protein DUF373 PF04123.8 EIE88830.1 - 0.11 11.4 0.6 0.12 11.3 0.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF373) APH PF01636.18 EIE88831.1 - 9.3e-35 120.4 0.0 1.3e-34 119.9 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EIE88831.1 - 0.078 12.1 0.0 0.18 10.9 0.0 1.6 1 1 0 1 1 1 0 Ecdysteroid kinase IATP PF04568.7 EIE88833.1 - 2.7e-06 27.3 7.6 3.4e-06 27.0 5.3 1.3 1 1 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP HemX PF04375.9 EIE88833.1 - 0.011 14.3 1.4 0.011 14.3 0.9 1.0 1 0 0 1 1 1 0 HemX Blo-t-5 PF11642.3 EIE88833.1 - 0.028 14.1 0.8 0.035 13.8 0.6 1.2 1 0 0 1 1 1 0 Mite allergen Blo t 5 DUF3560 PF12083.3 EIE88833.1 - 0.028 14.4 3.3 0.032 14.2 2.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3560) Glutaredoxin2_C PF04399.8 EIE88833.1 - 0.12 11.9 0.6 0.13 11.8 0.4 1.1 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain Bap31 PF05529.7 EIE88833.1 - 0.59 9.5 4.3 0.64 9.4 3.0 1.0 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like PEARLI-4 PF05278.7 EIE88833.1 - 0.83 8.9 7.8 1.2 8.4 5.3 1.3 1 1 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) TraI_2 PF07514.6 EIE88837.1 - 0.096 11.4 0.0 0.1 11.3 0.0 1.1 1 0 0 1 1 1 0 Putative helicase RicinB_lectin_2 PF14200.1 EIE88838.1 - 3.2e-05 24.2 2.3 0.0014 19.0 2.0 2.2 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 EIE88838.1 - 7.3e-05 22.7 2.4 0.00015 21.8 1.6 1.8 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain PPO1_DWL PF12142.3 EIE88838.1 - 0.003 17.0 2.5 0.04 13.4 0.7 2.8 1 1 2 3 3 3 1 Polyphenol oxidase middle domain CD20 PF04103.10 EIE88839.1 - 0.02 14.8 0.0 0.021 14.7 0.0 1.0 1 0 0 1 1 1 0 CD20-like family Methyltransf_11 PF08241.7 EIE88840.1 - 4.2e-16 59.2 0.0 1.4e-15 57.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIE88840.1 - 2.6e-12 46.7 0.0 7.8e-12 45.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIE88840.1 - 1.4e-11 44.2 0.3 4.2e-10 39.4 0.2 2.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIE88840.1 - 3.7e-11 43.3 0.2 3.2e-09 37.1 0.0 2.9 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIE88840.1 - 9.6e-11 41.9 0.0 9.5e-10 38.7 0.0 2.5 3 1 0 3 3 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIE88840.1 - 2.6e-09 37.6 0.1 3.7e-08 33.9 0.0 2.6 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIE88840.1 - 1.6e-08 34.5 0.0 4.4e-08 33.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EIE88840.1 - 4.6e-08 32.9 0.0 7.6e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase Ubie_methyltran PF01209.13 EIE88840.1 - 6.1e-07 28.7 0.0 1.3e-05 24.4 0.0 2.7 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 EIE88840.1 - 3e-06 26.4 0.0 2.4e-05 23.4 0.0 2.3 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_29 PF03141.11 EIE88840.1 - 7.5e-06 24.5 0.0 1.8e-05 23.2 0.0 1.5 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase CMAS PF02353.15 EIE88840.1 - 0.0064 15.6 0.1 2.8 6.9 0.0 2.2 2 0 0 2 2 2 2 Mycolic acid cyclopropane synthetase FtsJ PF01728.14 EIE88840.1 - 0.0092 15.9 0.1 0.026 14.4 0.1 1.8 1 1 0 1 1 1 1 FtsJ-like methyltransferase CheR PF01739.13 EIE88840.1 - 0.023 13.9 0.0 0.13 11.5 0.0 2.1 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain MetW PF07021.7 EIE88840.1 - 0.043 13.2 0.0 0.086 12.2 0.0 1.5 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW MTS PF05175.9 EIE88840.1 - 0.11 11.9 0.0 0.45 9.8 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase small domain Vps8 PF12816.2 EIE88846.1 - 6.1e-64 214.8 0.0 3.4e-62 209.1 0.0 3.0 3 0 0 3 3 3 1 Golgi CORVET complex core vacuolar protein 8 WD40 PF00400.27 EIE88846.1 - 0.05 13.5 0.7 0.7 9.8 0.4 2.8 2 0 0 2 2 2 0 WD domain, G-beta repeat RhoGAP PF00620.22 EIE88847.1 - 2.3e-26 92.2 5.5 4.1e-20 71.9 0.0 3.0 2 1 1 3 3 3 2 RhoGAP domain Pkinase PF00069.20 EIE88848.1 - 6.2e-66 222.2 0.0 9.8e-66 221.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE88848.1 - 7.4e-49 166.1 0.0 1.2e-48 165.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE88848.1 - 7e-08 31.7 0.0 2.4e-05 23.4 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Ras_bdg_2 PF14847.1 EIE88848.1 - 4.8e-06 26.4 0.0 9.9e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 Ras-binding domain of Byr2 APH PF01636.18 EIE88848.1 - 0.038 13.7 0.0 0.15 11.7 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 EIE88848.1 - 0.04 12.9 0.0 0.083 11.9 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Septin PF00735.13 EIE88849.1 - 3.2e-113 377.4 0.0 3.2e-113 377.4 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 EIE88849.1 - 2e-05 24.5 0.0 4.7e-05 23.3 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EIE88849.1 - 0.0018 18.1 3.6 0.78 9.5 0.0 3.1 2 1 1 3 3 3 2 Dynamin family DUF258 PF03193.11 EIE88849.1 - 0.0031 16.7 0.2 0.013 14.7 0.1 1.9 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 EIE88849.1 - 0.014 14.5 0.0 0.054 12.6 0.0 1.9 2 0 0 2 2 2 0 AIG1 family GTP_EFTU PF00009.22 EIE88849.1 - 0.019 14.3 0.1 0.063 12.7 0.0 1.8 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Miro PF08477.8 EIE88849.1 - 0.044 14.2 0.1 0.14 12.6 0.0 1.9 2 0 0 2 2 2 0 Miro-like protein AAA_22 PF13401.1 EIE88849.1 - 0.07 13.2 0.3 0.25 11.4 0.0 2.3 2 2 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EIE88849.1 - 0.16 12.7 5.1 1.2 9.9 3.5 2.6 1 1 0 1 1 1 0 AAA domain Ras PF00071.17 EIE88849.1 - 0.17 11.2 0.5 0.46 9.8 0.0 2.0 2 0 0 2 2 2 0 Ras family RRM_1 PF00076.17 EIE88854.1 - 2e-19 68.9 0.1 2.9e-19 68.4 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE88854.1 - 2.1e-12 46.8 0.1 3.3e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE88854.1 - 1.8e-09 37.3 0.0 2.7e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MIP-T3 PF10243.4 EIE88854.1 - 0.61 8.4 12.2 0.57 8.5 8.4 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Beta_protein PF14350.1 EIE88855.1 - 0.012 14.8 0.1 0.013 14.7 0.1 1.0 1 0 0 1 1 1 0 Beta protein DUF2404 PF10296.4 EIE88856.1 - 8.4e-25 86.7 0.0 1.6e-24 85.8 0.0 1.5 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) PH PF00169.24 EIE88856.1 - 1.9e-05 24.7 0.3 8.9e-05 22.6 0.2 2.2 2 1 0 2 2 2 1 PH domain PEN-2 PF10251.4 EIE88856.1 - 0.015 15.4 0.1 0.03 14.5 0.1 1.5 1 0 0 1 1 1 0 Presenilin enhancer-2 subunit of gamma secretase IncA PF04156.9 EIE88859.1 - 0.18 11.3 8.0 0.28 10.7 5.5 1.2 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 EIE88859.1 - 0.23 10.4 11.9 2.5 7.0 7.7 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF342 PF03961.8 EIE88859.1 - 1.8 6.9 11.8 3 6.1 8.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DivIC PF04977.10 EIE88859.1 - 7.4 6.1 10.7 1.5 8.3 3.3 2.5 1 1 1 2 2 2 0 Septum formation initiator ADH_zinc_N PF00107.21 EIE88860.1 - 1.7e-23 82.5 0.5 2.6e-23 82.0 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIE88860.1 - 2.9e-10 41.1 0.2 8.1e-10 39.6 0.0 1.8 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIE88860.1 - 1e-05 25.2 0.1 2.1e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NAD_binding_7 PF13241.1 EIE88860.1 - 0.027 14.6 0.1 0.048 13.9 0.1 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding ACP_syn_III_C PF08541.5 EIE88860.1 - 0.048 13.6 0.3 0.53 10.3 0.1 2.4 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal HTH_Tnp_Tc3_2 PF01498.13 EIE88863.1 - 0.015 15.3 0.1 0.031 14.3 0.0 1.6 1 0 0 1 1 1 0 Transposase KH_1 PF00013.24 EIE88864.1 - 7.5e-08 31.9 0.0 3.6e-05 23.3 0.0 2.4 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 EIE88864.1 - 3.9e-05 23.1 0.5 0.00059 19.4 0.1 3.0 2 1 0 2 2 2 1 KH domain HSF_DNA-bind PF00447.12 EIE88865.1 - 1.5e-17 63.6 0.1 2.3e-16 59.8 0.0 2.2 2 0 0 2 2 2 1 HSF-type DNA-binding B3_4 PF03483.12 EIE88866.1 - 4.9e-28 97.7 0.1 9.2e-28 96.8 0.1 1.5 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 EIE88866.1 - 4.1e-17 61.7 0.0 1.4e-15 56.8 0.0 2.5 2 0 0 2 2 2 1 tRNA synthetase B5 domain tRNA-synt_2d PF01409.15 EIE88866.1 - 0.00054 19.2 0.0 0.0014 17.8 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetases class II core domain (F) DUF2740 PF10872.3 EIE88866.1 - 0.065 12.9 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2740) LRR_4 PF12799.2 EIE88867.1 - 1.4e-37 126.7 38.4 4.6e-09 35.7 0.1 9.2 5 2 5 10 10 10 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EIE88867.1 - 2.3e-28 97.7 42.4 2.2e-07 30.5 0.1 8.4 3 3 5 8 8 8 8 Leucine rich repeat LRR_1 PF00560.28 EIE88867.1 - 9e-12 43.3 44.1 0.2 11.8 0.2 14.4 12 3 2 14 14 14 4 Leucine Rich Repeat LRR_7 PF13504.1 EIE88867.1 - 9.3e-09 34.0 37.3 3.2 8.3 0.2 13.0 13 1 1 14 14 14 3 Leucine rich repeat LRR_6 PF13516.1 EIE88867.1 - 1.2e-05 24.9 28.9 0.95 9.7 0.1 11.0 10 3 1 11 11 11 1 Leucine Rich repeat LRR_9 PF14580.1 EIE88867.1 - 0.00013 21.5 15.4 0.012 15.1 0.2 3.9 1 1 3 4 4 4 3 Leucine-rich repeat Peptidase_M18 PF02127.10 EIE88868.1 - 4.5e-170 565.8 0.5 5.1e-170 565.6 0.4 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 EIE88868.1 - 4.4e-08 32.2 0.3 4.4e-06 25.6 0.1 2.2 1 1 0 2 2 2 2 M42 glutamyl aminopeptidase Peptidase_M20 PF01546.23 EIE88868.1 - 0.0017 17.8 0.3 0.0038 16.7 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 SLAM PF06214.6 EIE88868.1 - 0.054 13.4 0.3 0.28 11.1 0.1 2.2 2 0 0 2 2 2 0 Signaling lymphocytic activation molecule (SLAM) protein YHYH PF14240.1 EIE88870.1 - 0.02 14.5 0.0 0.025 14.2 0.0 1.1 1 0 0 1 1 1 0 YHYH protein WD40 PF00400.27 EIE88872.1 - 1.2e-12 47.2 8.1 0.00024 20.8 0.4 5.0 4 1 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 EIE88872.1 - 0.0043 15.2 0.2 2.3 6.2 0.0 3.1 2 1 1 3 3 3 3 Nucleoporin Nup120/160 DUF2248 PF10005.4 EIE88872.1 - 0.032 13.1 0.0 0.1 11.4 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2248) Peptidase_S66 PF02016.10 EIE88872.1 - 0.11 11.4 0.0 0.27 10.1 0.0 1.7 2 0 0 2 2 2 0 LD-carboxypeptidase UIM PF02809.15 EIE88872.1 - 3.9 7.3 11.7 21 5.0 0.6 4.4 5 0 0 5 5 5 0 Ubiquitin interaction motif Pkinase PF00069.20 EIE88873.1 - 4.3e-62 209.6 0.0 5.1e-62 209.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE88873.1 - 1.3e-22 80.1 0.0 1.6e-22 79.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE88873.1 - 1.6e-05 24.0 0.0 0.00021 20.3 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EIE88873.1 - 0.0037 16.3 0.0 0.0053 15.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIE88873.1 - 0.0052 16.5 0.0 0.008 15.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EIE88873.1 - 0.0097 14.5 0.6 0.021 13.4 0.5 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.15 EIE88873.1 - 0.047 13.2 0.1 0.068 12.7 0.1 1.4 1 1 0 1 1 1 0 Choline/ethanolamine kinase Peptidase_S41 PF03572.13 EIE88874.1 - 1.5e-07 31.0 0.0 3.3e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Peptidase family S41 CI-B14_5a PF07347.7 EIE88875.1 - 0.0019 17.8 0.3 0.0031 17.2 0.2 1.3 1 1 0 1 1 1 1 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) Metallophos PF00149.23 EIE88876.1 - 0.12 11.6 14.3 0.23 10.8 0.6 3.6 2 1 1 3 3 3 0 Calcineurin-like phosphoesterase DUF320 PF03777.8 EIE88877.1 - 0.025 14.3 0.0 0.03 14.0 0.0 1.1 1 0 0 1 1 1 0 Small secreted domain (DUF320) RVT_1 PF00078.22 EIE88878.1 - 6.8e-19 68.0 0.0 9.4e-19 67.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GCR1_C PF12550.3 EIE88879.1 - 6.1e-15 54.8 0.8 1.3e-14 53.7 0.4 1.8 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes NUDIX PF00293.23 EIE88881.1 - 3.1e-30 104.5 0.0 4.2e-30 104.1 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain Mito_carr PF00153.22 EIE88883.1 - 9.3e-48 159.8 1.7 9.4e-24 82.9 0.0 2.6 3 0 0 3 3 3 2 Mitochondrial carrier protein RNA12 PF10443.4 EIE88884.1 - 1.2e-88 297.4 7.4 4.8e-87 292.2 5.1 2.4 1 1 0 1 1 1 1 RNA12 protein Arch_ATPase PF01637.13 EIE88884.1 - 2.1e-10 40.7 4.5 7.3e-05 22.5 0.0 2.7 3 0 0 3 3 3 2 Archaeal ATPase RRM_1 PF00076.17 EIE88884.1 - 3.2e-07 29.8 0.0 8.7e-07 28.4 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_16 PF13191.1 EIE88884.1 - 0.0001 22.3 0.0 0.00021 21.3 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EIE88884.1 - 0.00033 20.7 0.0 0.00087 19.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 EIE88884.1 - 0.00069 20.1 2.2 0.0047 17.4 0.6 3.0 2 1 0 2 2 2 1 Miro-like protein RRM_6 PF14259.1 EIE88884.1 - 0.00079 19.3 0.0 0.0031 17.4 0.0 2.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE88884.1 - 0.0079 16.0 0.0 0.023 14.5 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2487 PF10673.4 EIE88884.1 - 0.01 15.6 0.0 0.037 13.8 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF2487) DUF815 PF05673.8 EIE88884.1 - 0.015 14.2 0.0 0.03 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_29 PF13555.1 EIE88884.1 - 0.022 14.2 0.0 0.054 13.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EIE88884.1 - 0.034 14.1 0.1 0.074 13.0 0.1 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase T2SE PF00437.15 EIE88884.1 - 0.046 12.6 0.0 0.11 11.4 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_10 PF12846.2 EIE88884.1 - 0.084 12.3 0.0 0.64 9.4 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain Sel1 PF08238.7 EIE88885.1 - 6.6e-44 147.3 14.8 1.5e-07 31.8 0.1 7.4 7 0 0 7 7 7 7 Sel1 repeat NAD_binding_6 PF08030.7 EIE88888.1 - 3.1e-12 46.6 0.4 1.3e-11 44.5 0.1 2.1 2 1 1 3 3 3 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EIE88888.1 - 8.9e-10 38.7 17.8 1.5e-09 37.9 10.8 2.4 2 1 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.16 EIE88888.1 - 0.008 16.7 0.0 0.015 15.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Trm112p PF03966.11 EIE88889.1 - 9.1e-20 70.8 0.1 1.1e-19 70.5 0.1 1.1 1 0 0 1 1 1 1 Trm112p-like protein His_kinase PF06580.8 EIE88889.1 - 0.015 15.1 0.1 0.031 14.1 0.0 1.7 1 1 1 2 2 2 0 Histidine kinase SRP54_N PF02881.14 EIE88889.1 - 0.058 13.5 0.0 0.082 13.0 0.0 1.4 1 1 0 1 1 1 0 SRP54-type protein, helical bundle domain zinc_ribbon_5 PF13719.1 EIE88889.1 - 0.072 12.6 0.1 0.072 12.6 0.1 1.8 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EIE88889.1 - 0.073 12.7 0.1 0.073 12.7 0.0 1.8 2 0 0 2 2 2 0 zinc-ribbon domain MOZART1 PF12554.3 EIE88889.1 - 0.079 12.4 0.0 0.21 11.0 0.0 1.8 2 0 0 2 2 2 0 Mitotic-spindle organizing gamma-tubulin ring associated COX5B PF01215.14 EIE88889.1 - 0.083 12.5 0.1 0.14 11.8 0.1 1.4 1 1 0 1 1 1 0 Cytochrome c oxidase subunit Vb PhnA_Zn_Ribbon PF08274.7 EIE88889.1 - 0.11 12.2 0.1 0.24 11.2 0.1 1.5 1 0 0 1 1 1 0 PhnA Zinc-Ribbon A2L_zn_ribbon PF08792.5 EIE88889.1 - 0.17 11.4 0.2 0.17 11.4 0.1 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-NADH-PPase PF09297.6 EIE88889.1 - 0.29 10.6 0.3 0.29 10.6 0.2 1.7 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain zf-C3HC4_2 PF13923.1 EIE88890.1 - 6.9e-08 32.3 14.5 1.5e-07 31.2 8.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EIE88890.1 - 0.0002 20.9 10.7 0.0015 18.2 5.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIE88890.1 - 0.00065 19.3 11.7 0.00065 19.3 8.1 2.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIE88890.1 - 0.0016 18.1 10.6 0.0016 18.1 7.3 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 EIE88890.1 - 0.0016 18.2 14.0 0.0016 18.2 9.7 2.2 2 0 0 2 2 2 1 Ring finger domain zf-Apc11 PF12861.2 EIE88890.1 - 0.011 15.5 2.6 0.011 15.5 1.8 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.3 EIE88890.1 - 0.087 12.3 6.0 0.19 11.2 4.1 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DZR PF12773.2 EIE88890.1 - 2.4 8.0 9.7 0.62 9.9 0.9 2.7 3 0 0 3 3 3 0 Double zinc ribbon zf-rbx1 PF12678.2 EIE88890.1 - 7.7 6.7 13.4 86 3.3 0.0 3.0 2 1 0 2 2 2 0 RING-H2 zinc finger DUF3457 PF11939.3 EIE88891.1 - 0.041 13.3 0.1 0.058 12.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3457) FAM176 PF14851.1 EIE88891.1 - 0.35 10.5 4.9 0.49 10.0 3.4 1.1 1 0 0 1 1 1 0 FAM176 family NAD_binding_1 PF00175.16 EIE88892.1 - 3.6e-28 98.3 0.0 5.3e-28 97.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EIE88892.1 - 1.1e-07 31.9 0.0 4.4e-06 26.6 0.0 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_6 PF00970.19 EIE88892.1 - 3.8e-06 26.9 0.0 6.6e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Ribosomal_S13 PF00416.17 EIE88893.1 - 3.8e-38 130.2 1.7 4.6e-38 129.9 1.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 EIE88893.1 - 0.0011 17.5 0.0 0.0013 17.4 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) DUF1822 PF08852.6 EIE88893.1 - 0.091 11.5 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1822) VPS9 PF02204.13 EIE88894.1 - 0.024 14.6 0.6 0.093 12.7 0.0 2.3 2 0 0 2 2 2 0 Vacuolar sorting protein 9 (VPS9) domain bact-PGI_C PF10432.4 EIE88894.1 - 0.073 12.7 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial phospho-glucose isomerase C-terminal region Carn_acyltransf PF00755.15 EIE88895.1 - 5.8e-150 500.2 0.0 6.6e-150 500.0 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase IL2 PF00715.12 EIE88895.1 - 0.11 12.2 0.1 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Interleukin 2 Syntaxin PF00804.20 EIE88896.1 - 2e-14 53.5 5.8 2e-14 53.5 4.0 2.2 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.14 EIE88896.1 - 2.7e-08 33.3 0.4 2.7e-08 33.3 0.3 3.3 3 1 1 4 4 4 1 SNARE domain Sin3_corepress PF08295.7 EIE88896.1 - 0.35 10.6 3.9 0.22 11.3 0.2 2.2 2 0 0 2 2 2 0 Sin3 family co-repressor Syntaxin-6_N PF09177.6 EIE88896.1 - 0.62 10.4 6.9 0.45 10.9 1.3 2.5 2 0 0 2 2 2 0 Syntaxin 6, N-terminal TEX13 PF15186.1 EIE88896.1 - 0.93 9.0 5.4 1.2 8.6 0.1 2.6 2 1 1 3 3 3 0 Testis-expressed sequence 13 protein family Spectrin PF00435.16 EIE88896.1 - 0.98 9.7 10.1 0.11 12.8 1.0 2.9 2 1 0 2 2 2 0 Spectrin repeat ALMT PF11744.3 EIE88896.1 - 1.5 7.3 6.1 1.1 7.7 3.1 1.5 1 1 0 1 1 1 0 Aluminium activated malate transporter Osmo_CC PF08946.5 EIE88896.1 - 1.9 8.5 5.4 27 4.8 0.7 3.4 3 0 0 3 3 3 0 Osmosensory transporter coiled coil APC_CDC26 PF10471.4 EIE88896.1 - 4 8.2 10.6 5.8 7.7 2.1 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 Thioredoxin PF00085.15 EIE88897.1 - 3.2e-30 103.8 0.0 3.5e-30 103.7 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EIE88897.1 - 8.3e-11 42.0 0.1 5.9e-10 39.3 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EIE88897.1 - 1.3e-10 41.2 0.1 1.3e-09 38.0 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.1 EIE88897.1 - 1.1e-06 28.6 0.1 1.6e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 EIE88897.1 - 7e-06 25.6 0.0 7.9e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.16 EIE88897.1 - 9e-06 25.3 0.1 1.8e-05 24.4 0.1 1.5 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EIE88897.1 - 7.1e-05 22.3 0.1 9.9e-05 21.9 0.0 1.3 1 1 0 1 1 1 1 Redoxin Glutaredoxin PF00462.19 EIE88897.1 - 8.4e-05 22.4 0.1 0.00014 21.7 0.1 1.4 1 0 0 1 1 1 1 Glutaredoxin HyaE PF07449.6 EIE88897.1 - 0.0022 17.8 0.0 0.0042 16.9 0.0 1.4 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE DIM1 PF02966.11 EIE88897.1 - 0.0042 16.5 0.0 0.0045 16.4 0.0 1.1 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredox_DsbH PF03190.10 EIE88897.1 - 0.13 12.0 0.2 0.19 11.4 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function, DUF255 SEEEED PF14797.1 EIE88898.1 - 0.0041 17.2 2.1 0.0041 17.2 1.5 1.9 2 0 0 2 2 2 1 Serine-rich region of AP3B1, clathrin-adaptor complex GCD14 PF08704.5 EIE88899.1 - 1.1e-90 303.4 0.0 1.2e-90 303.2 0.0 1.0 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_18 PF12847.2 EIE88899.1 - 1.5e-07 31.9 0.0 2.8e-07 31.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIE88899.1 - 2.3e-07 30.5 0.0 4.4e-07 29.5 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIE88899.1 - 5.3e-06 26.4 0.0 7.6e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EIE88899.1 - 6.2e-06 25.8 0.0 1.1e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.1 EIE88899.1 - 1.2e-05 26.0 0.0 2.1e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EIE88899.1 - 0.0068 15.7 0.0 0.0093 15.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain RrnaAD PF00398.15 EIE88899.1 - 0.048 12.6 0.0 0.074 12.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_3 PF01596.12 EIE88899.1 - 0.14 11.1 0.0 0.26 10.3 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase CAP_GLY PF01302.20 EIE88900.1 - 1e-21 76.3 0.0 1.7e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 CAP-Gly domain Ribosomal_60s PF00428.14 EIE88900.1 - 0.00019 21.7 5.7 0.00091 19.5 3.9 2.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein Aminotran_1_2 PF00155.16 EIE88900.1 - 0.025 13.5 0.1 0.064 12.1 0.1 1.6 1 0 0 1 1 1 0 Aminotransferase class I and II Usp PF00582.21 EIE88901.1 - 1.7e-22 80.1 0.1 2.1e-22 79.8 0.1 1.1 1 0 0 1 1 1 1 Universal stress protein family Metallophos_2 PF12850.2 EIE88901.1 - 0.044 13.6 0.1 0.051 13.4 0.1 1.2 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Pkinase PF00069.20 EIE88902.1 - 1e-73 247.6 0.0 1.5e-73 247.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE88902.1 - 2e-50 171.2 0.0 3.1e-50 170.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 EIE88902.1 - 7.8e-21 74.2 0.8 3.1e-20 72.3 0.1 2.4 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.1 EIE88902.1 - 1.1e-06 27.8 0.0 2.6e-06 26.6 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EIE88902.1 - 0.006 16.3 0.0 0.24 11.1 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EIE88902.1 - 0.0086 15.1 0.2 0.017 14.1 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family DSHCT PF08148.7 EIE88902.1 - 0.096 11.9 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 DSHCT (NUC185) domain UQ_con PF00179.21 EIE88903.1 - 2.8e-44 149.9 0.0 3.1e-44 149.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EIE88903.1 - 0.0019 18.0 0.0 0.0023 17.7 0.0 1.3 1 0 0 1 1 1 1 RWD domain UFC1 PF08694.6 EIE88903.1 - 0.0085 15.5 0.0 0.0097 15.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 RicinB_lectin_2 PF14200.1 EIE88905.1 - 0.0003 21.1 0.0 0.0024 18.2 0.0 1.8 1 1 1 2 2 2 1 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 EIE88905.1 - 0.015 15.3 0.0 0.11 12.5 0.0 1.9 1 1 1 2 2 2 0 Ricin-type beta-trefoil lectin domain Lum_binding PF00677.12 EIE88906.1 - 1.7e-45 152.7 1.6 2.7e-23 81.6 0.1 2.1 2 0 0 2 2 2 2 Lumazine binding domain Peptidase_M41 PF01434.13 EIE88906.1 - 0.028 13.9 0.5 0.48 9.8 0.2 2.1 1 1 1 2 2 2 0 Peptidase family M41 DUF1767 PF08585.7 EIE88907.1 - 0.00021 21.5 0.1 0.0004 20.6 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF1767) Rep-A_N PF04057.7 EIE88907.1 - 0.033 13.9 0.0 0.05 13.4 0.0 1.3 1 0 0 1 1 1 0 Replication factor-A protein 1, N-terminal domain TraO PF10626.4 EIE88908.1 - 0.18 11.1 1.1 0.32 10.3 0.8 1.4 1 0 0 1 1 1 0 Conjugative transposon protein TraO RNA_pol_Rpb8 PF03870.10 EIE88909.1 - 3.2e-32 111.5 0.1 3.6e-32 111.4 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 Sialidase_penC PF12135.3 EIE88909.1 - 0.58 9.8 2.3 2.1 8.0 0.4 2.3 2 0 0 2 2 2 0 Sialidase enzyme penultimate C terminal domain RVT_1 PF00078.22 EIE88913.1 - 4.8e-16 58.7 0.0 7.4e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.1 EIE88913.1 - 0.00027 21.2 1.2 0.00052 20.2 0.9 1.4 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase CAP_GLY PF01302.20 EIE88915.1 - 1.9e-18 65.9 0.4 3.1e-18 65.2 0.3 1.3 1 0 0 1 1 1 1 CAP-Gly domain Presenilin PF01080.12 EIE88915.1 - 1.7 7.3 11.3 2.3 6.9 7.8 1.2 1 0 0 1 1 1 0 Presenilin SUFU_C PF12470.3 EIE88915.1 - 2.5 7.6 6.8 4.3 6.8 4.7 1.3 1 0 0 1 1 1 0 Suppressor of Fused Gli/Ci N terminal binding domain SOBP PF15279.1 EIE88915.1 - 2.5 8.3 15.3 3.1 8.1 10.6 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein BRCT PF00533.21 EIE88916.1 - 1e-13 51.1 2.0 1.1e-09 38.2 0.0 3.6 3 1 0 3 3 3 3 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EIE88916.1 - 8.4e-10 38.3 0.7 0.00021 21.0 0.0 3.3 3 0 0 3 3 3 2 twin BRCT domain TCTP PF00838.12 EIE88917.1 - 1.1e-54 184.8 0.4 1.2e-54 184.7 0.3 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Phage_int_SAM_4 PF13495.1 EIE88917.1 - 0.12 12.7 0.4 0.23 11.8 0.0 1.6 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain Mus7 PF09462.5 EIE88917.1 - 0.13 11.0 0.1 0.15 10.8 0.0 1.1 1 0 0 1 1 1 0 Mus7/MMS22 family PDZ_1 PF12812.2 EIE88919.1 - 5.3e-36 122.3 0.0 7.7e-26 89.7 0.0 2.8 2 0 0 2 2 2 2 PDZ-like domain PDZ_2 PF13180.1 EIE88919.1 - 1.5e-18 66.4 0.3 2.8e-06 27.1 0.0 4.8 4 0 0 4 4 4 3 PDZ domain Trypsin_2 PF13365.1 EIE88919.1 - 4.8e-12 45.9 0.0 2e-11 43.8 0.0 2.1 2 0 0 2 2 2 1 Trypsin-like peptidase domain PDZ PF00595.19 EIE88919.1 - 6.4e-12 45.4 0.2 0.0012 18.9 0.0 4.4 4 0 0 4 4 4 2 PDZ domain (Also known as DHR or GLGF) Trypsin PF00089.21 EIE88919.1 - 0.00018 21.1 0.0 0.0039 16.8 0.0 2.7 3 0 0 3 3 3 1 Trypsin Tricorn_PDZ PF14685.1 EIE88919.1 - 0.00037 20.2 0.4 0.15 11.8 0.0 3.6 4 0 0 4 4 4 1 Tricorn protease PDZ domain Peptidase_S7 PF00949.16 EIE88919.1 - 0.056 12.8 0.4 0.13 11.6 0.3 1.5 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease Peptidase_S3 PF00944.14 EIE88919.1 - 0.077 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Alphavirus core protein Peptidase_S46 PF10459.4 EIE88919.1 - 0.13 10.6 0.5 0.33 9.3 0.1 1.7 2 0 0 2 2 2 0 Peptidase S46 DUF31 PF01732.11 EIE88919.1 - 0.27 10.5 0.1 0.46 9.7 0.1 1.3 1 0 0 1 1 1 0 Putative peptidase (DUF31) Ipi1_N PF12333.3 EIE88920.1 - 1.3e-19 70.0 0.4 5.9e-19 67.9 0.1 2.3 2 0 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation HEAT_EZ PF13513.1 EIE88920.1 - 0.059 13.8 0.0 0.16 12.5 0.0 1.8 1 0 0 1 1 1 0 HEAT-like repeat HEAT PF02985.17 EIE88920.1 - 0.11 12.6 0.0 0.78 9.9 0.0 2.4 2 0 0 2 2 2 0 HEAT repeat HEAT PF02985.17 EIE88921.1 - 2e-25 86.5 9.7 8.3e-06 25.4 0.0 8.8 8 0 0 8 8 8 5 HEAT repeat HEAT_EZ PF13513.1 EIE88921.1 - 8e-23 80.2 21.0 9.8e-09 35.4 0.0 9.9 9 2 3 12 12 10 4 HEAT-like repeat HEAT_2 PF13646.1 EIE88921.1 - 1.3e-21 76.6 4.1 7.1e-07 29.4 0.1 6.0 4 2 2 6 6 6 6 HEAT repeats Vac14_Fab1_bd PF12755.2 EIE88921.1 - 2.4e-11 43.8 0.2 0.21 11.9 0.0 6.3 5 2 2 7 7 6 3 Vacuolar 14 Fab1-binding region Arm PF00514.18 EIE88921.1 - 2.7e-08 33.3 5.3 0.15 11.9 0.2 5.9 5 0 0 5 5 5 3 Armadillo/beta-catenin-like repeat IBN_N PF03810.14 EIE88921.1 - 6.9e-06 25.8 0.0 3.6e-05 23.5 0.0 2.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain Adaptin_N PF01602.15 EIE88921.1 - 1.3e-05 23.7 3.5 0.042 12.1 0.0 3.9 3 1 0 4 4 4 2 Adaptin N terminal region Cnd1 PF12717.2 EIE88921.1 - 8e-05 22.5 3.6 5 6.9 0.0 5.2 3 2 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Xpo1 PF08389.7 EIE88921.1 - 0.00029 20.7 0.9 2.2 8.1 0.0 4.2 4 0 0 4 4 4 1 Exportin 1-like protein RasGEF_N_2 PF14663.1 EIE88921.1 - 0.00035 20.4 1.5 0.13 12.2 0.0 3.5 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain TIP120 PF08623.5 EIE88921.1 - 0.0013 18.3 0.0 1.3 8.5 0.0 3.6 3 0 0 3 3 3 1 TATA-binding protein interacting (TIP20) UME PF08064.8 EIE88921.1 - 0.017 15.0 1.0 0.99 9.3 0.0 3.9 5 0 0 5 5 5 0 UME (NUC010) domain ParcG PF10274.4 EIE88921.1 - 0.023 14.6 3.2 4.9 7.0 0.1 3.6 4 0 0 4 4 4 0 Parkin co-regulated protein MHCassoc_trimer PF08831.5 EIE88921.1 - 0.1 12.4 0.1 1.3 8.9 0.0 2.8 2 0 0 2 2 2 0 Class II MHC-associated invariant chain trimerisation domain Cohesin_HEAT PF12765.2 EIE88921.1 - 0.13 12.2 1.2 2.3e+02 1.8 0.0 4.5 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion VTC PF09359.5 EIE88922.1 - 4e-73 245.8 0.0 7.8e-73 244.9 0.0 1.5 1 0 0 1 1 1 1 VTC domain DUF202 PF02656.10 EIE88922.1 - 2.3e-09 37.3 6.4 2.3e-09 37.3 4.4 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SPX PF03105.14 EIE88922.1 - 0.28 10.9 15.4 0.17 11.6 0.5 3.3 2 2 2 4 4 4 0 SPX domain VTC PF09359.5 EIE88923.1 - 1.2e-68 231.2 0.1 6.6e-68 228.7 0.0 2.1 2 0 0 2 2 2 1 VTC domain SPX PF03105.14 EIE88923.1 - 4.6e-25 88.9 7.4 8.9e-12 45.3 2.0 3.4 1 1 1 2 2 2 2 SPX domain DUF202 PF02656.10 EIE88923.1 - 0.034 14.3 0.0 0.073 13.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF202) Glyco_hydro_18 PF00704.23 EIE88924.1 - 5.9e-93 312.0 0.1 6.8e-93 311.8 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 HSP90 PF00183.13 EIE88925.1 - 3.8e-256 850.6 35.0 5.8e-256 850.0 24.3 1.3 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.21 EIE88925.1 - 1.2e-11 44.2 0.1 2.4e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EIE88925.1 - 8.7e-11 41.6 0.1 8.7e-11 41.6 0.1 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF399 PF04187.8 EIE88925.1 - 0.022 14.2 0.3 0.41 10.1 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function, DUF399 Pox_P35 PF03213.9 EIE88925.1 - 0.085 11.8 3.8 0.2 10.6 2.6 1.6 1 0 0 1 1 1 0 Poxvirus P35 protein SH3_7 PF12914.2 EIE88926.1 - 0.055 13.2 0.0 0.081 12.7 0.0 1.3 1 0 0 1 1 1 0 SH3 domain of SH3b2 type Ribosomal_L29 PF00831.18 EIE88927.1 - 1.2e-14 53.6 2.1 1.2e-14 53.6 1.4 2.2 2 1 0 2 2 2 1 Ribosomal L29 protein Ribosomal_S9 PF00380.14 EIE88927.1 - 0.12 12.6 3.1 0.21 11.8 2.2 1.5 1 1 0 1 1 1 0 Ribosomal protein S9/S16 CENP-B_N PF04218.8 EIE88927.1 - 0.76 9.2 4.7 4.3 6.8 0.0 3.0 3 0 0 3 3 3 0 CENP-B N-terminal DNA-binding domain Ribosomal_L37ae PF01780.14 EIE88928.1 - 1.3e-40 137.1 10.7 1.4e-40 137.0 7.4 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.2 EIE88928.1 - 0.00094 18.9 2.4 0.0014 18.4 1.6 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain A2L_zn_ribbon PF08792.5 EIE88928.1 - 0.005 16.2 2.6 0.84 9.1 0.1 2.2 2 0 0 2 2 2 2 A2L zinc ribbon domain zf-FCS PF06467.9 EIE88928.1 - 0.015 14.9 1.7 0.75 9.4 0.1 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif Rep_fac-A_C PF08646.5 EIE88928.1 - 0.052 13.2 0.5 0.068 12.8 0.3 1.3 1 0 0 1 1 1 0 Replication factor-A C terminal domain zf-BED PF02892.10 EIE88928.1 - 0.059 13.1 5.0 0.088 12.5 0.3 2.3 1 1 1 2 2 2 0 BED zinc finger Zn-ribbon_8 PF09723.5 EIE88928.1 - 0.11 12.4 1.5 0.9 9.5 0.1 2.2 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.1 EIE88928.1 - 0.15 12.3 1.1 2.5 8.5 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger double domain zf-Sec23_Sec24 PF04810.10 EIE88928.1 - 0.27 10.8 1.2 5.7 6.5 0.0 2.1 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Elf1 PF05129.8 EIE88928.1 - 0.3 10.8 2.3 0.54 9.9 1.6 1.5 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like zf-MYND PF01753.13 EIE88928.1 - 0.34 10.8 2.4 0.57 10.0 1.6 1.3 1 0 0 1 1 1 0 MYND finger zf-C2H2 PF00096.21 EIE88928.1 - 1.4 9.4 3.6 18 5.8 0.3 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type CarbpepA_inh PF02977.10 EIE88928.1 - 3.3 7.3 5.7 16 5.1 3.9 2.0 1 1 0 1 1 1 0 Carboxypeptidase A inhibitor DUF4391 PF14335.1 EIE88931.1 - 0.046 13.0 4.7 0.067 12.5 3.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4391) KLRAQ PF10205.4 EIE88931.1 - 0.064 13.2 0.4 0.067 13.2 0.3 1.1 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein Phage_GP20 PF06810.6 EIE88931.1 - 0.075 12.4 3.7 0.074 12.4 2.6 1.0 1 0 0 1 1 1 0 Phage minor structural protein GP20 DUF1690 PF07956.6 EIE88931.1 - 0.11 12.4 1.4 0.12 12.3 1.0 1.1 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) Fzo_mitofusin PF04799.8 EIE88931.1 - 0.11 11.8 1.1 0.13 11.6 0.8 1.1 1 0 0 1 1 1 0 fzo-like conserved region DivIC PF04977.10 EIE88931.1 - 0.43 10.0 3.0 0.27 10.7 1.0 1.5 1 1 1 2 2 2 0 Septum formation initiator HR1 PF02185.11 EIE88931.1 - 1.1 9.0 6.4 0.38 10.5 2.6 1.5 2 0 0 2 2 2 0 Hr1 repeat YvrJ PF12841.2 EIE88931.1 - 2.1 7.7 5.4 0.65 9.3 1.3 2.0 2 1 0 2 2 2 0 YvrJ protein family DUF1162 PF06650.7 EIE88932.1 - 2e-63 214.1 0.0 2.4e-59 200.8 0.0 3.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1162) Chorein_N PF12624.2 EIE88932.1 - 1.2e-20 73.1 1.0 4.6e-13 48.7 0.0 2.7 1 1 1 2 2 2 2 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 EIE88932.1 - 8.3e-09 35.5 0.0 4.4e-08 33.1 0.0 2.3 2 0 0 2 2 2 1 ATG C terminal domain ADP_ribosyl_GH PF03747.9 EIE88933.1 - 1.4e-18 67.7 0.0 2.4e-18 66.9 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylglycohydrolase DUF4011 PF13195.1 EIE88934.1 - 0.44 10.5 9.1 0.5 10.3 6.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) Endonuc_Holl PF10107.4 EIE88934.1 - 0.86 9.2 7.6 0.98 9.0 5.3 1.1 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase FlxA PF14282.1 EIE88934.1 - 1.4 8.8 14.0 1.6 8.7 1.6 2.1 1 1 1 2 2 2 0 FlxA-like protein DUF2890 PF11081.3 EIE88934.1 - 1.6 8.7 12.8 1.9 8.4 8.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Tom22 PF04281.8 EIE88934.1 - 2.7 7.5 8.1 3.7 7.0 5.6 1.3 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 DNA_pol_phi PF04931.8 EIE88934.1 - 7.9 4.1 14.6 8.1 4.0 10.1 1.0 1 0 0 1 1 1 0 DNA polymerase phi OrfB_Zn_ribbon PF07282.6 EIE88935.1 - 0.079 12.6 0.0 0.22 11.1 0.0 1.7 1 0 0 1 1 1 0 Putative transposase DNA-binding domain FUSC-like PF12805.2 EIE88936.1 - 0.11 11.4 0.1 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS Pkinase PF00069.20 EIE88937.1 - 2.1e-23 82.8 4.4 1.2e-21 77.0 0.0 2.9 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE88937.1 - 1.4e-09 37.4 0.1 5e-09 35.6 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.17 EIE88937.1 - 0.017 14.5 0.3 0.071 12.4 0.0 2.1 2 0 0 2 2 2 0 RIO1 family Pox_ser-thr_kin PF05445.6 EIE88937.1 - 0.017 13.9 0.0 0.027 13.3 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF1168 PF06658.7 EIE88937.1 - 0.028 13.9 7.0 0.051 13.0 4.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Peptidase_S49_N PF08496.5 EIE88937.1 - 0.23 11.2 3.9 0.41 10.4 2.7 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Aminotran_1_2 PF00155.16 EIE88938.1 - 7.1e-51 173.2 0.0 9.9e-51 172.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EIE88938.1 - 8.6e-06 25.0 0.1 1.4e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase OKR_DC_1 PF01276.15 EIE88938.1 - 0.0069 14.9 0.0 0.013 14.0 0.0 1.4 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Cys_Met_Meta_PP PF01053.15 EIE88938.1 - 0.013 13.8 0.0 0.022 13.0 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EIE88938.1 - 0.03 13.3 0.0 0.049 12.6 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 EIE88938.1 - 0.044 12.5 0.0 0.073 11.7 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V CAP_N PF01213.14 EIE88939.1 - 6.8 5.8 7.2 7.1 5.8 5.0 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal FLILHELTA PF10306.4 EIE88940.1 - 1.4e-11 44.2 0.1 2.9e-11 43.2 0.0 1.5 1 1 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.8 EIE88940.1 - 0.00094 19.4 0.5 0.0023 18.2 0.2 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) RRM_1 PF00076.17 EIE88941.1 - 5.3e-48 160.5 1.4 4.9e-21 74.1 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE88941.1 - 5.1e-32 109.6 0.1 5.7e-16 58.2 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE88941.1 - 7.8e-27 92.8 0.2 4.7e-10 39.1 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 EIE88941.1 - 4.2e-22 78.2 0.1 8.2e-22 77.2 0.1 1.5 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_3 PF08777.6 EIE88941.1 - 5.6e-05 22.9 0.0 0.027 14.3 0.0 2.6 2 0 0 2 2 2 2 RNA binding motif Nup35_RRM_2 PF14605.1 EIE88941.1 - 0.0014 18.3 0.0 1.7 8.4 0.0 3.2 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif DUF1777 PF08648.7 EIE88941.1 - 0.065 12.9 44.9 0.12 12.1 31.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) MIP-T3 PF10243.4 EIE88941.1 - 3.9 5.8 15.9 5.9 5.2 11.0 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 LINES_N PF14694.1 EIE88942.1 - 0.026 13.8 0.3 0.026 13.8 0.2 1.0 1 0 0 1 1 1 0 Lines N-terminus O-FucT PF10250.4 EIE88944.1 - 1.9e-10 40.4 0.2 6.4e-09 35.3 0.1 2.5 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Thioredoxin PF00085.15 EIE88945.1 - 4.4e-09 35.9 0.1 4.9e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EIE88945.1 - 0.0022 18.0 0.1 0.003 17.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like DUF2847 PF11009.3 EIE88945.1 - 0.044 13.3 0.2 0.053 13.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) NAD_binding_4 PF07993.7 EIE88948.1 - 1.6e-47 161.5 0.0 2.9e-47 160.6 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Acyltransferase PF01553.16 EIE88948.1 - 8.9e-07 28.4 0.0 1.9e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase Epimerase PF01370.16 EIE88948.1 - 3.4e-06 26.6 0.4 1.7e-05 24.3 0.3 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EIE88948.1 - 0.013 14.2 1.6 0.46 9.1 0.7 2.7 2 1 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EIE88948.1 - 0.017 14.0 0.4 0.42 9.4 0.3 2.5 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein NuA4 PF09340.5 EIE88949.1 - 6.5e-26 89.7 0.7 6.5e-26 89.7 0.5 2.2 2 1 0 2 2 2 1 Histone acetyltransferase subunit NuA4 ATG16 PF08614.6 EIE88949.1 - 0.074 12.8 8.4 0.095 12.5 1.2 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) PASTA PF03793.14 EIE88949.1 - 0.094 12.3 0.0 0.3 10.7 0.0 1.8 1 0 0 1 1 1 0 PASTA domain Biotin_lipoyl_2 PF13533.1 EIE88949.1 - 0.47 10.1 2.6 0.55 9.9 0.1 2.1 2 0 0 2 2 2 0 Biotin-lipoyl like Uds1 PF15456.1 EIE88949.1 - 1.6 8.7 9.2 0.23 11.4 0.6 2.2 2 0 0 2 2 2 0 Up-regulated During Septation MFS_1 PF07690.11 EIE88951.1 - 1.8e-19 69.6 56.3 2.5e-14 52.7 23.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily CCDC84 PF14968.1 EIE88952.1 - 0.022 14.3 4.2 0.028 13.9 2.9 1.1 1 0 0 1 1 1 0 Coiled coil protein 84 HTH_Tnp_Tc3_2 PF01498.13 EIE88953.1 - 1.6e-16 60.0 1.1 3.5e-16 58.9 0.8 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.1 EIE88953.1 - 2.9e-16 59.5 0.0 5e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 EIE88953.1 - 2.3e-08 34.1 0.4 3.6e-07 30.3 0.0 2.7 3 0 0 3 3 3 1 Winged helix-turn helix HTH_23 PF13384.1 EIE88953.1 - 0.00016 21.2 0.1 0.00061 19.3 0.0 2.0 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.1 EIE88953.1 - 0.0018 18.2 0.0 0.0062 16.5 0.0 2.0 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_17 PF12728.2 EIE88953.1 - 0.0074 16.5 0.6 0.29 11.3 0.0 3.0 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_24 PF13412.1 EIE88953.1 - 0.011 15.1 0.0 0.14 11.5 0.0 2.5 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding HTH_38 PF13936.1 EIE88953.1 - 0.012 15.1 0.0 0.036 13.6 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_7 PF02796.10 EIE88953.1 - 0.046 13.5 0.4 1 9.2 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase SpoIIID PF12116.3 EIE88953.1 - 0.046 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Stage III sporulation protein D HTH_IclR PF09339.5 EIE88953.1 - 0.049 13.2 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain MerR PF00376.18 EIE88953.1 - 0.07 12.6 0.3 7.2 6.2 0.0 3.0 3 0 0 3 3 3 0 MerR family regulatory protein zf-CCHC PF00098.18 EIE88955.1 - 5.7e-05 22.8 4.2 0.00045 20.0 0.0 2.6 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_6 PF15288.1 EIE88955.1 - 0.013 15.1 0.1 0.04 13.5 0.1 1.9 1 0 0 1 1 1 0 Zinc knuckle Ubie_methyltran PF01209.13 EIE88956.1 - 3.8e-15 55.6 0.4 2.6e-11 43.1 0.0 2.0 1 1 1 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 EIE88956.1 - 7.3e-05 23.1 0.0 0.00011 22.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIE88956.1 - 0.0027 17.2 0.0 0.0037 16.8 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain ATP_bind_1 PF03029.12 EIE88956.1 - 0.0029 17.2 0.0 0.003 17.1 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein Methyltransf_8 PF05148.10 EIE88956.1 - 0.014 15.0 0.0 0.016 14.8 0.0 1.1 1 0 0 1 1 1 0 Hypothetical methyltransferase HrpJ PF07201.6 EIE88958.1 - 0.25 11.3 2.5 0.28 11.1 1.7 1.0 1 0 0 1 1 1 0 HrpJ-like domain zf-Sec23_Sec24 PF04810.10 EIE88959.1 - 0.0069 15.9 0.0 0.0099 15.4 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Ima1_N PF09779.4 EIE88959.1 - 0.064 13.7 0.0 0.084 13.3 0.0 1.3 1 0 0 1 1 1 0 Ima1 N-terminal domain Sec16 PF12932.2 EIE88959.1 - 0.092 12.7 0.0 0.097 12.6 0.0 1.1 1 0 0 1 1 1 0 Vesicle coat trafficking protein Sec16 mid-region zf-Di19 PF05605.7 EIE88959.1 - 1.2 9.2 3.4 1.2 9.3 0.1 2.4 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Pkinase PF00069.20 EIE88960.1 - 1.9e-63 214.0 0.0 4.6e-63 212.7 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE88960.1 - 3.2e-34 118.1 0.1 1e-33 116.4 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 EIE88960.1 - 4e-05 22.7 0.1 6.9e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EIE88960.1 - 0.0007 18.6 0.0 0.0026 16.7 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EIE88960.1 - 0.049 13.3 0.1 0.18 11.4 0.1 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.17 EIE88960.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 RIO1 family FAM70 PF14967.1 EIE88960.1 - 1.4 8.0 6.4 2.4 7.2 4.4 1.3 1 0 0 1 1 1 0 FAM70 protein HTH_Tnp_Tc3_2 PF01498.13 EIE88961.1 - 1.6e-16 60.0 1.1 3.5e-16 58.9 0.8 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.1 EIE88961.1 - 2.9e-16 59.5 0.0 5e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 EIE88961.1 - 2.3e-08 34.1 0.4 3.6e-07 30.3 0.0 2.7 3 0 0 3 3 3 1 Winged helix-turn helix HTH_23 PF13384.1 EIE88961.1 - 0.00016 21.2 0.1 0.00061 19.3 0.0 2.0 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.1 EIE88961.1 - 0.0018 18.2 0.0 0.0062 16.5 0.0 2.0 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_17 PF12728.2 EIE88961.1 - 0.0074 16.5 0.6 0.29 11.3 0.0 3.0 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_24 PF13412.1 EIE88961.1 - 0.011 15.1 0.0 0.14 11.5 0.0 2.5 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding HTH_38 PF13936.1 EIE88961.1 - 0.012 15.1 0.0 0.036 13.6 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_7 PF02796.10 EIE88961.1 - 0.046 13.5 0.4 1 9.2 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase SpoIIID PF12116.3 EIE88961.1 - 0.046 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Stage III sporulation protein D HTH_IclR PF09339.5 EIE88961.1 - 0.049 13.2 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain MerR PF00376.18 EIE88961.1 - 0.07 12.6 0.3 7.2 6.2 0.0 3.0 3 0 0 3 3 3 0 MerR family regulatory protein AA_permease_2 PF13520.1 EIE88963.1 - 1.8e-50 171.7 33.4 1.8e-50 171.7 23.2 2.0 1 1 1 2 2 2 1 Amino acid permease AA_permease PF00324.16 EIE88963.1 - 2.3e-16 59.2 43.4 2e-15 56.1 30.1 1.9 1 1 0 1 1 1 1 Amino acid permease DUF2305 PF10230.4 EIE88966.1 - 9.1e-49 166.2 1.1 9e-39 133.4 0.0 2.0 1 1 1 2 2 2 2 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 EIE88966.1 - 1e-09 38.6 0.0 1.6e-09 37.9 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIE88966.1 - 2.5e-05 24.0 0.0 4.1e-05 23.3 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF3089 PF11288.3 EIE88966.1 - 0.004 16.3 0.0 0.0076 15.4 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3089) Abhydrolase_1 PF00561.15 EIE88966.1 - 0.012 15.1 0.0 0.018 14.6 0.0 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.8 EIE88966.1 - 0.059 12.9 0.0 0.21 11.1 0.0 1.8 2 0 0 2 2 2 0 PGAP1-like protein DUF900 PF05990.7 EIE88966.1 - 0.13 11.5 0.0 4.4 6.5 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) MRG PF05712.8 EIE88967.1 - 7e-34 116.4 6.3 3.4e-19 68.4 0.3 2.5 2 1 1 3 3 3 2 MRG Tudor-knot PF11717.3 EIE88967.1 - 1.2e-08 34.4 1.4 1.2e-08 34.4 0.9 2.8 3 0 0 3 3 3 1 RNA binding activity-knot of a chromodomain Chromo PF00385.19 EIE88967.1 - 0.1 12.2 2.7 0.38 10.4 1.9 2.0 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Phage_integrase PF00589.17 EIE88968.1 - 6.7e-07 29.1 0.5 8.8e-07 28.7 0.3 1.2 1 0 0 1 1 1 1 Phage integrase family Malate_synthase PF01274.17 EIE88968.1 - 0.0081 14.2 1.0 0.43 8.5 0.0 2.1 1 1 1 2 2 2 2 Malate synthase pRN1_helical PF13010.1 EIE88970.1 - 0.0025 17.4 0.9 0.0051 16.4 0.6 1.5 1 0 0 1 1 1 1 Primase helical domain DASH_Duo1 PF08651.5 EIE88970.1 - 0.019 14.5 2.9 0.027 14.0 0.0 2.5 3 0 0 3 3 3 0 DASH complex subunit Duo1 Transaldolase PF00923.14 EIE88970.1 - 0.12 11.4 3.9 0.58 9.2 0.2 2.2 2 0 0 2 2 2 0 Transaldolase FliG_N PF14842.1 EIE88970.1 - 0.66 10.1 4.3 3.7 7.7 0.2 3.0 1 1 1 3 3 3 0 FliG N-terminal domain DUF2422 PF10337.4 EIE88970.1 - 1.7 7.3 5.2 5.3 5.7 3.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2422) zf-CCHC PF00098.18 EIE88973.1 - 0.068 13.1 1.8 0.11 12.4 1.2 1.3 1 0 0 1 1 1 0 Zinc knuckle Exo_endo_phos PF03372.18 EIE88974.1 - 0.002 18.0 0.0 0.0022 18.0 0.0 1.0 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EIE88975.1 - 0.033 13.8 0.0 0.1 12.1 0.0 1.9 1 1 1 2 2 2 0 Endonuclease-reverse transcriptase RVT_1 PF00078.22 EIE88976.1 - 4.9e-25 88.1 0.0 7.5e-25 87.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Crinivirus_P26 PF07416.6 EIE88976.1 - 0.1 12.1 0.1 0.16 11.4 0.1 1.2 1 0 0 1 1 1 0 Crinivirus P26 protein zf-RVT PF13966.1 EIE88977.1 - 3.1e-05 24.1 0.7 4.2e-05 23.7 0.5 1.2 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase GST_N_2 PF13409.1 EIE88978.1 - 3e-22 78.4 0.0 4.9e-22 77.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIE88978.1 - 1.4e-06 28.0 0.0 4.8e-06 26.3 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EIE88978.1 - 1.2e-05 25.1 0.1 2.9e-05 23.9 0.1 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EIE88978.1 - 3e-05 24.1 0.0 0.00048 20.2 0.0 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Tropomyosin_1 PF12718.2 EIE88979.1 - 2.7e-16 59.6 28.6 2.1e-11 43.8 7.5 2.1 1 1 1 2 2 2 2 Tropomyosin like Tropomyosin PF00261.15 EIE88979.1 - 5.1e-07 29.0 25.4 7.1e-07 28.5 17.6 1.2 1 0 0 1 1 1 1 Tropomyosin DUF948 PF06103.6 EIE88979.1 - 9.2e-05 22.2 2.5 9.2e-05 22.2 1.8 2.3 1 1 2 3 3 3 1 Bacterial protein of unknown function (DUF948) KLRAQ PF10205.4 EIE88979.1 - 0.00026 20.9 11.9 0.00058 19.8 3.3 2.1 1 1 1 2 2 2 1 Predicted coiled-coil domain-containing protein CENP-F_leu_zip PF10473.4 EIE88979.1 - 0.00054 19.8 25.7 0.028 14.2 8.7 2.1 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Flagellin_C PF00700.16 EIE88979.1 - 0.00082 19.4 3.8 0.00082 19.4 2.6 2.2 2 1 1 3 3 2 1 Bacterial flagellin C-terminal helical region Occludin_ELL PF07303.8 EIE88979.1 - 0.0021 18.7 8.8 0.0026 18.4 4.0 2.3 1 1 1 2 2 2 1 Occludin homology domain ATG16 PF08614.6 EIE88979.1 - 0.0045 16.8 21.6 0.012 15.4 14.9 1.6 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) MscS_porin PF12795.2 EIE88979.1 - 0.0048 16.2 24.3 0.016 14.5 17.0 1.4 1 1 0 1 1 1 1 Mechanosensitive ion channel porin domain WXG100 PF06013.7 EIE88979.1 - 0.0057 16.6 16.6 0.16 11.9 1.9 3.3 2 1 1 3 3 3 2 Proteins of 100 residues with WXG Myosin_tail_1 PF01576.14 EIE88979.1 - 0.0057 14.4 25.2 0.0066 14.2 17.5 1.0 1 0 0 1 1 1 1 Myosin tail Uds1 PF15456.1 EIE88979.1 - 0.0082 16.1 16.3 0.079 12.9 9.9 2.0 2 0 0 2 2 2 1 Up-regulated During Septation APG6 PF04111.7 EIE88979.1 - 0.0086 15.1 22.6 0.0098 14.9 15.6 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 FliD_C PF07195.7 EIE88979.1 - 0.0097 15.2 13.4 0.26 10.5 3.0 2.1 1 1 1 2 2 2 2 Flagellar hook-associated protein 2 C-terminus GAS PF13851.1 EIE88979.1 - 0.01 15.0 23.0 0.019 14.1 13.1 1.8 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF3450 PF11932.3 EIE88979.1 - 0.011 14.9 19.6 0.13 11.5 4.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) WEMBL PF05701.6 EIE88979.1 - 0.012 14.0 29.4 0.02 13.3 20.4 1.3 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Spc7 PF08317.6 EIE88979.1 - 0.015 14.0 20.6 0.019 13.6 5.9 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein ADIP PF11559.3 EIE88979.1 - 0.015 15.2 22.7 0.08 12.8 8.9 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Tup_N PF08581.5 EIE88979.1 - 0.015 15.4 13.2 0.017 15.3 3.2 2.3 1 1 0 2 2 2 0 Tup N-terminal Nup54 PF13874.1 EIE88979.1 - 0.02 14.5 15.3 0.026 14.1 6.9 2.0 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Laminin_I PF06008.9 EIE88979.1 - 0.021 14.1 18.5 0.13 11.5 12.5 1.8 1 1 1 2 2 2 0 Laminin Domain I DUF869 PF05911.6 EIE88979.1 - 0.022 13.0 18.4 0.026 12.7 12.8 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) Filament PF00038.16 EIE88979.1 - 0.041 13.3 19.7 0.037 13.5 10.1 1.8 1 1 0 1 1 1 0 Intermediate filament protein Reo_sigmaC PF04582.7 EIE88979.1 - 0.044 12.9 1.2 0.055 12.6 0.8 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein IZUMO PF15005.1 EIE88979.1 - 0.046 13.7 5.7 0.051 13.6 3.9 1.2 1 0 0 1 1 1 0 Izumo sperm-egg fusion TMF_DNA_bd PF12329.3 EIE88979.1 - 0.051 13.3 29.9 0.61 9.9 3.4 2.9 1 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4200 PF13863.1 EIE88979.1 - 0.057 13.3 26.5 0.044 13.7 7.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF812 PF05667.6 EIE88979.1 - 0.058 11.9 16.9 0.087 11.3 11.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) FlaC_arch PF05377.6 EIE88979.1 - 0.075 12.9 11.4 1.2 9.1 0.1 3.7 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) Syntaxin PF00804.20 EIE88979.1 - 0.076 13.1 14.2 0.92 9.7 6.2 2.1 1 1 1 2 2 2 0 Syntaxin Snapin_Pallidin PF14712.1 EIE88979.1 - 0.083 13.2 11.7 0.44 10.8 0.1 2.5 1 1 1 2 2 2 0 Snapin/Pallidin Atg14 PF10186.4 EIE88979.1 - 0.094 11.6 17.3 0.082 11.8 10.7 1.7 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Prefoldin_2 PF01920.15 EIE88979.1 - 0.097 12.4 26.2 0.22 11.2 5.1 3.1 1 1 2 3 3 3 0 Prefoldin subunit HalX PF08663.5 EIE88979.1 - 0.11 12.5 20.0 0.72 9.8 5.2 3.4 2 1 1 3 3 3 0 HalX domain DUF3584 PF12128.3 EIE88979.1 - 0.11 9.7 21.2 0.13 9.5 14.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Nsp1_C PF05064.8 EIE88979.1 - 0.13 11.9 15.4 0.063 12.9 4.3 2.1 1 1 1 2 2 2 0 Nsp1-like C-terminal region Vps5 PF09325.5 EIE88979.1 - 0.14 11.4 15.9 0.22 10.7 5.2 2.3 1 1 0 2 2 2 0 Vps5 C terminal like Laminin_II PF06009.7 EIE88979.1 - 0.16 11.7 11.8 0.26 11.0 7.8 1.6 1 1 0 1 1 1 0 Laminin Domain II DUF4201 PF13870.1 EIE88979.1 - 0.19 11.1 17.2 0.98 8.8 5.7 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) TPR_MLP1_2 PF07926.7 EIE88979.1 - 0.19 11.4 27.4 1.2 8.9 18.8 2.4 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein AAA_13 PF13166.1 EIE88979.1 - 0.31 9.4 18.4 0.36 9.2 11.0 1.6 1 1 0 1 1 1 0 AAA domain Mnd1 PF03962.10 EIE88979.1 - 0.35 10.5 21.9 1.4 8.5 15.2 1.8 1 1 0 1 1 1 0 Mnd1 family GrpE PF01025.14 EIE88979.1 - 0.35 10.3 26.1 0.25 10.8 2.9 3.0 1 1 2 3 3 3 0 GrpE Syntaxin-6_N PF09177.6 EIE88979.1 - 0.41 11.0 13.4 7.2 7.0 5.8 2.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF2704 PF10866.3 EIE88979.1 - 0.41 10.0 2.6 0.45 9.8 1.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2704) TBPIP PF07106.8 EIE88979.1 - 0.41 10.1 18.4 9.3 5.7 12.8 2.2 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Transposase_22 PF02994.9 EIE88979.1 - 0.43 9.0 13.0 0.51 8.7 9.0 1.1 1 0 0 1 1 1 0 L1 transposable element Tektin PF03148.9 EIE88979.1 - 0.44 9.0 21.0 0.069 11.6 7.2 2.0 1 1 1 2 2 2 0 Tektin family DUF4337 PF14235.1 EIE88979.1 - 0.45 10.3 25.8 2.4 7.9 8.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) Fib_alpha PF08702.5 EIE88979.1 - 0.54 10.3 11.3 1.5 8.9 7.1 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Lebercilin PF15619.1 EIE88979.1 - 0.55 9.6 22.8 1.8 7.9 15.8 1.8 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease AAA_27 PF13514.1 EIE88979.1 - 0.58 7.7 23.2 0.51 7.9 5.5 1.6 1 1 0 1 1 1 0 AAA domain DUF724 PF05266.9 EIE88979.1 - 0.62 9.6 20.7 0.57 9.7 5.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Fmp27_WPPW PF10359.4 EIE88979.1 - 0.73 8.1 14.3 1.7 6.9 9.8 1.6 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Seryl_tRNA_N PF02403.17 EIE88979.1 - 0.73 9.8 24.3 1.5 8.9 8.7 2.5 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain RmuC PF02646.11 EIE88979.1 - 0.78 8.5 11.9 0.58 8.9 6.1 2.1 1 1 2 3 3 3 0 RmuC family DUF972 PF06156.8 EIE88979.1 - 0.8 10.0 17.2 1.6 9.1 5.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF1664 PF07889.7 EIE88979.1 - 0.82 9.4 8.1 3.9 7.2 3.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Exonuc_VII_L PF02601.10 EIE88979.1 - 0.84 8.7 13.5 0.95 8.5 9.3 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Peptidase_S15 PF02129.13 EIE88979.1 - 0.89 8.9 3.4 1 8.7 2.4 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Striatin PF08232.7 EIE88979.1 - 0.99 9.7 15.2 1.4 9.2 10.5 1.3 1 0 0 1 1 1 0 Striatin family V-ATPase_C PF03223.10 EIE88979.1 - 1 8.2 7.8 1.4 7.7 5.4 1.3 1 0 0 1 1 1 0 V-ATPase subunit C IncA PF04156.9 EIE88979.1 - 1.1 8.7 22.9 2.5 7.6 15.9 1.5 1 1 0 1 1 1 0 IncA protein ERM PF00769.14 EIE88979.1 - 1.2 8.6 28.8 2.6 7.4 19.2 1.8 1 1 0 1 1 1 0 Ezrin/radixin/moesin family CDC37_N PF03234.9 EIE88979.1 - 1.3 9.3 17.1 4.5 7.5 11.9 1.7 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding DUF641 PF04859.7 EIE88979.1 - 1.4 8.6 16.5 0.32 10.7 6.8 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Cortex-I_coil PF09304.5 EIE88979.1 - 1.5 8.9 21.6 1.2 9.2 7.1 2.5 1 1 1 2 2 2 0 Cortexillin I, coiled coil V_ATPase_I PF01496.14 EIE88979.1 - 1.5 6.5 13.2 2.3 5.9 9.1 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FH2 PF02181.18 EIE88979.1 - 1.5 7.5 13.9 0.15 10.9 4.0 2.0 1 1 1 2 2 2 0 Formin Homology 2 Domain MtrG PF04210.8 EIE88979.1 - 1.8 8.2 7.1 23 4.7 0.1 3.7 1 1 3 4 4 4 0 Tetrahydromethanopterin S-methyltransferase, subunit G FliJ PF02050.11 EIE88979.1 - 2.1 8.3 23.1 4.2 7.4 8.6 2.2 1 1 1 2 2 2 0 Flagellar FliJ protein Spc24 PF08286.6 EIE88979.1 - 2.3 7.9 19.6 2.2 7.9 1.6 2.6 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 DUF4472 PF14739.1 EIE88979.1 - 2.3 8.7 15.6 3.8 8.0 7.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) BLOC1_2 PF10046.4 EIE88979.1 - 2.3 8.4 14.6 8.6 6.5 5.5 2.5 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3552 PF12072.3 EIE88979.1 - 2.4 7.3 24.6 72 2.5 15.4 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) Bacillus_HBL PF05791.6 EIE88979.1 - 2.6 7.3 12.8 20 4.5 8.9 2.0 1 1 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) CALCOCO1 PF07888.6 EIE88979.1 - 2.6 6.2 15.9 3.5 5.7 11.0 1.3 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like bZIP_1 PF00170.16 EIE88979.1 - 2.8 7.9 21.9 1.6 8.7 3.4 3.6 2 2 1 3 3 3 0 bZIP transcription factor FUSC PF04632.7 EIE88979.1 - 2.9 6.2 8.3 3.2 6.0 5.8 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family U1snRNP70_N PF12220.3 EIE88979.1 - 3.1 8.1 9.8 1.2 9.4 4.2 2.1 1 1 1 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Allexi_40kDa PF05549.6 EIE88979.1 - 3.4 6.8 6.6 4.7 6.4 4.4 1.4 1 1 0 1 1 1 0 Allexivirus 40kDa protein CENP-Q PF13094.1 EIE88979.1 - 3.5 7.6 28.0 1.4e+02 2.4 19.4 2.1 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF2681 PF10883.3 EIE88979.1 - 3.5 7.8 17.5 2 8.6 4.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2681) DUF2968 PF11180.3 EIE88979.1 - 3.7 6.8 20.4 8.7 5.6 6.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) TMCO5 PF14992.1 EIE88979.1 - 3.8 6.5 17.2 9 5.3 4.5 2.0 1 1 1 2 2 2 0 TMCO5 family DUF904 PF06005.7 EIE88979.1 - 3.9 7.8 25.6 0.88 9.9 3.3 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF904) PilJ PF13675.1 EIE88979.1 - 4 7.8 11.1 7 7.0 4.4 2.2 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Viral_P18 PF04521.8 EIE88979.1 - 4.5 6.7 17.0 3.6 7.0 4.3 2.7 1 1 2 3 3 3 0 ssRNA positive strand viral 18kD cysteine rich protein TMPIT PF07851.8 EIE88979.1 - 4.6 6.2 9.3 5.6 5.9 6.5 1.2 1 0 0 1 1 1 0 TMPIT-like protein FlxA PF14282.1 EIE88979.1 - 4.7 7.2 18.8 27 4.7 6.0 2.6 1 1 1 2 2 2 0 FlxA-like protein Phlebovirus_NSM PF07246.6 EIE88979.1 - 4.7 6.2 11.5 5.3 6.1 8.0 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Ax_dynein_light PF10211.4 EIE88979.1 - 4.8 6.9 22.4 9.6 5.9 2.9 2.5 1 1 1 2 2 2 0 Axonemal dynein light chain DivIC PF04977.10 EIE88979.1 - 5.3 6.5 25.7 7.3 6.1 3.3 3.3 1 1 2 3 3 3 0 Septum formation initiator PspB PF06667.7 EIE88979.1 - 5.3 7.0 10.4 0.88 9.5 2.3 2.7 2 2 1 3 3 2 0 Phage shock protein B OmpH PF03938.9 EIE88979.1 - 6 6.7 30.6 5.8 6.8 11.1 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Lectin_N PF03954.9 EIE88979.1 - 6.2 6.2 7.8 5.2 6.4 3.1 2.0 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain EMP24_GP25L PF01105.19 EIE88979.1 - 7 6.3 10.9 51 3.5 7.5 2.3 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD TMF_TATA_bd PF12325.3 EIE88979.1 - 8.5 6.1 19.6 1.2e+02 2.4 12.6 2.6 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding NPV_P10 PF05531.7 EIE88979.1 - 8.8 6.6 9.0 74 3.7 0.2 2.8 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein KxDL PF10241.4 EIE88979.1 - 9.5 6.2 10.4 14 5.6 4.2 2.6 1 1 1 2 2 2 0 Uncharacterized conserved protein TIP49 PF06068.8 EIE88980.1 - 1.7e-190 632.9 1.1 2e-190 632.6 0.8 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 EIE88980.1 - 4.2e-11 43.1 0.6 1.2e-06 28.7 0.0 3.1 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EIE88980.1 - 2.2e-10 40.0 1.9 1.1e-06 27.9 0.0 3.1 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EIE88980.1 - 2.8e-08 33.9 0.0 0.013 15.5 0.0 3.0 3 0 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 EIE88980.1 - 1.4e-05 25.1 0.0 0.077 13.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EIE88980.1 - 0.0021 17.7 0.0 0.31 10.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EIE88980.1 - 0.0021 17.2 0.1 0.066 12.3 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 EIE88980.1 - 0.0031 16.9 0.0 0.0057 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EIE88980.1 - 0.0031 17.2 0.0 0.0068 16.1 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain Sigma54_activat PF00158.21 EIE88980.1 - 0.0054 16.2 0.1 2.8 7.3 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_18 PF13238.1 EIE88980.1 - 0.0066 16.7 0.0 0.029 14.6 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EIE88980.1 - 0.0089 15.9 0.0 0.029 14.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EIE88980.1 - 0.014 15.2 0.0 0.46 10.3 0.0 2.5 2 1 0 2 2 2 0 AAA domain DUF2075 PF09848.4 EIE88980.1 - 0.025 13.5 0.0 0.043 12.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 EIE88980.1 - 0.029 14.1 0.7 0.51 10.1 0.0 2.3 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit IstB_IS21 PF01695.12 EIE88980.1 - 0.035 13.5 0.1 0.074 12.4 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_17 PF13207.1 EIE88980.1 - 0.045 14.5 0.0 0.13 13.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EIE88980.1 - 0.045 12.8 0.1 0.1 11.6 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin Parvo_NS1 PF01057.12 EIE88980.1 - 0.12 11.1 0.0 0.22 10.3 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Reticulon PF02453.12 EIE88981.1 - 2.3e-21 76.1 1.9 3e-21 75.7 1.3 1.1 1 0 0 1 1 1 1 Reticulon SET PF00856.23 EIE88984.1 - 2.1e-12 47.6 0.1 1.9e-11 44.5 0.0 2.2 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.13 EIE88984.1 - 7.6e-07 28.9 9.7 7.6e-07 28.9 6.8 1.9 2 0 0 2 2 2 1 MYND finger Herpes_UL4 PF03277.8 EIE88984.1 - 0.009 15.2 0.1 0.019 14.1 0.1 1.5 1 0 0 1 1 1 1 Herpesvirus UL4 family WBP-1 PF11669.3 EIE88985.1 - 0.01 15.9 0.0 5.8 7.0 0.0 2.9 2 0 0 2 2 2 0 WW domain-binding protein 1 Sigma_1s PF02454.11 EIE88985.1 - 0.046 13.4 0.8 0.36 10.5 0.1 2.6 2 0 0 2 2 2 0 Sigma 1s protein DUF4381 PF14316.1 EIE88985.1 - 3.7 7.6 9.3 0.32 11.0 0.1 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4381) Cullin PF00888.17 EIE88987.1 - 1.8e-81 274.4 28.9 1e-77 262.0 18.0 2.0 1 1 1 2 2 2 2 Cullin family HbrB PF08539.6 EIE88987.1 - 0.00067 19.5 2.0 0.00079 19.2 0.5 1.8 2 0 0 2 2 2 1 HbrB-like DUF2431 PF10354.4 EIE88987.1 - 0.044 13.7 0.8 0.089 12.7 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2431) Ribosomal_S7 PF00177.16 EIE88987.1 - 0.14 11.7 1.0 4.1 6.9 0.4 2.8 2 0 0 2 2 2 0 Ribosomal protein S7p/S5e rve PF00665.21 EIE88990.1 - 1.1e-16 60.9 0.0 4.8e-16 58.9 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE88990.1 - 6.3e-11 42.0 0.5 5.5e-10 38.9 0.2 2.6 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE88990.1 - 2.8e-08 33.3 2.9 9.9e-08 31.5 0.1 2.9 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain RVP PF00077.15 EIE88990.1 - 0.002 17.9 0.1 0.0088 15.9 0.1 2.2 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 EIE88990.1 - 0.0042 17.5 0.1 0.0092 16.4 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.12 EIE88990.1 - 0.033 14.2 0.0 0.26 11.4 0.0 2.6 1 0 0 1 1 1 0 Retrotransposon gag protein DDE_3 PF13358.1 EIE88991.1 - 3.5e-20 72.2 0.1 7.2e-20 71.2 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE88991.1 - 2e-07 30.9 1.4 2e-07 30.9 1.0 2.3 1 1 1 2 2 2 1 Transposase rve PF00665.21 EIE88991.1 - 0.037 14.1 0.1 0.089 12.8 0.0 1.9 1 1 0 1 1 1 0 Integrase core domain HTH_12 PF08461.5 EIE88991.1 - 0.086 12.5 0.1 0.28 10.9 0.0 1.8 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain HTH_29 PF13551.1 EIE88991.1 - 0.21 11.7 2.9 0.19 11.8 0.8 1.9 2 0 0 2 2 2 0 Winged helix-turn helix DUF1033 PF06279.6 EIE88991.1 - 0.36 10.6 0.0 0.36 10.6 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1033) NFRKB_winged PF14465.1 EIE88991.1 - 0.37 10.6 3.4 5.5 6.8 0.4 2.9 2 1 0 2 2 2 0 NFRKB Winged Helix-like HTH_32 PF13565.1 EIE88991.1 - 0.96 10.2 7.5 0.19 12.5 1.1 2.7 4 0 0 4 4 4 0 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.1 EIE88991.1 - 1.6 7.9 3.7 1.1 8.5 0.1 2.4 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 HTH_Tnp_Tc3_2 PF01498.13 EIE88992.1 - 3.2e-08 33.5 2.3 3.2e-08 33.5 1.6 2.5 2 1 1 3 3 3 1 Transposase DDE_3 PF13358.1 EIE88994.1 - 2.7e-18 66.1 0.0 7e-18 64.7 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE88994.1 - 4.7e-09 36.1 0.7 2e-08 34.1 0.7 2.0 2 1 0 2 2 2 1 Transposase DDE_3 PF13358.1 EIE88995.1 - 9e-18 64.4 0.4 8.1e-17 61.3 0.0 2.5 3 0 0 3 3 3 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE88995.1 - 1e-09 38.3 1.8 2.4e-09 37.0 1.2 1.7 1 0 0 1 1 1 1 Transposase GCR1_C PF12550.3 EIE88996.1 - 5.1e-26 90.3 0.7 5.1e-25 87.1 0.2 2.6 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes DUF1246 PF06849.7 EIE88996.1 - 0.0058 16.3 0.1 0.057 13.1 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1246) Transposase_21 PF02992.9 EIE88997.1 - 1.9e-21 76.1 0.0 3.6e-21 75.3 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DUF1258 PF06869.7 EIE88997.1 - 0.0055 15.8 0.0 0.0096 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) DDE_Tnp_IS1595 PF12762.2 EIE88999.1 - 1.8e-07 31.0 0.1 4.1e-07 29.9 0.1 1.6 1 0 0 1 1 1 1 ISXO2-like transposase domain ESAG1 PF03238.8 EIE88999.1 - 0.013 14.8 3.0 0.028 13.7 0.5 2.0 2 0 0 2 2 2 0 ESAG protein DUF1203 PF06718.6 EIE89000.1 - 0.069 12.9 0.0 0.2 11.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1203) VIT1 PF01988.14 EIE89000.1 - 1.5 8.2 4.4 2.7 7.4 3.1 1.4 1 1 0 1 1 1 0 VIT family Transposase_21 PF02992.9 EIE89001.1 - 7.3e-20 71.0 0.0 1.1e-19 70.3 0.0 1.2 1 0 0 1 1 1 1 Transposase family tnp2 HTH_Tnp_Tc3_2 PF01498.13 EIE89002.1 - 8e-06 25.8 0.3 1e-05 25.5 0.2 1.1 1 0 0 1 1 1 1 Transposase DDE_Tnp_ISAZ013 PF07592.6 EIE89002.1 - 0.091 11.4 0.2 0.091 11.4 0.1 1.0 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain Galactosyl_T PF01762.16 EIE89002.1 - 0.1 12.1 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Galactosyltransferase TRAPP PF04051.11 EIE89002.1 - 0.11 12.0 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 Transport protein particle (TRAPP) component DDE_3 PF13358.1 EIE89003.1 - 6e-18 64.9 0.1 1.4e-17 63.7 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE89003.1 - 5.4e-12 45.5 1.0 5.4e-12 45.5 0.7 2.2 3 0 0 3 3 3 1 Transposase HTH_29 PF13551.1 EIE89003.1 - 0.0002 21.4 0.7 0.0004 20.5 0.1 1.8 2 0 0 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.1 EIE89003.1 - 0.00094 18.7 0.1 0.0025 17.3 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_7 PF02796.10 EIE89003.1 - 0.0074 16.1 0.0 0.021 14.6 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_30 PF13556.1 EIE89003.1 - 0.021 14.3 0.0 0.17 11.4 0.0 2.1 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain HTH_38 PF13936.1 EIE89003.1 - 0.031 13.8 0.0 0.11 12.0 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain RecX PF02631.11 EIE89003.1 - 0.13 12.4 0.3 0.27 11.4 0.2 1.5 1 0 0 1 1 1 0 RecX family DUF2534 PF10749.4 EIE89004.1 - 0.14 12.1 1.1 0.18 11.7 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2534) DDE_Tnp_IS1595 PF12762.2 EIE89006.1 - 2.8e-22 79.1 0.3 3.5e-22 78.8 0.2 1.1 1 0 0 1 1 1 1 ISXO2-like transposase domain DDE_Tnp_IS66 PF03050.9 EIE89006.1 - 0.0012 18.1 0.1 0.0016 17.7 0.0 1.1 1 0 0 1 1 1 1 Transposase IS66 family HTH_Tnp_Tc3_2 PF01498.13 EIE89007.1 - 7.8e-16 57.8 0.3 1.4e-15 57.1 0.2 1.4 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.1 EIE89007.1 - 0.015 15.4 0.1 0.034 14.2 0.0 1.7 2 0 0 2 2 2 0 Winged helix-turn helix DDE_Tnp_ISAZ013 PF07592.6 EIE89007.1 - 0.03 13.0 0.0 0.036 12.8 0.0 1.2 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain HTH_32 PF13565.1 EIE89007.1 - 0.079 13.7 0.4 1.1 10.1 0.0 2.6 3 0 0 3 3 3 0 Homeodomain-like domain HTH_21 PF13276.1 EIE89007.1 - 0.092 12.7 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 HTH-like domain HTH_12 PF08461.5 EIE89007.1 - 0.16 11.7 0.1 0.69 9.6 0.0 1.9 1 1 1 2 2 2 0 Ribonuclease R winged-helix domain DDE_Tnp_IS1595 PF12762.2 EIE89008.1 - 1e-06 28.6 0.1 1.9e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 ISXO2-like transposase domain HTH_Tnp_Tc3_2 PF01498.13 EIE89009.1 - 5.6e-16 58.3 0.4 8.4e-16 57.7 0.3 1.3 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.1 EIE89009.1 - 0.00032 21.4 1.4 0.0051 17.5 0.0 2.4 2 1 1 3 3 3 1 Homeodomain-like domain HTH_29 PF13551.1 EIE89009.1 - 0.0027 17.8 1.1 0.0035 17.4 0.1 1.7 2 0 0 2 2 2 1 Winged helix-turn helix HTH_21 PF13276.1 EIE89009.1 - 0.023 14.6 0.0 0.051 13.5 0.0 1.5 1 0 0 1 1 1 0 HTH-like domain DDE_Tnp_IS1595 PF12762.2 EIE89010.1 - 1e-06 28.6 0.1 1.9e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 ISXO2-like transposase domain Retrotrans_gag PF03732.12 EIE89011.1 - 7.3e-06 25.9 0.3 1.7e-05 24.7 0.2 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein UBN2 PF14223.1 EIE89011.1 - 0.015 15.0 0.1 0.039 13.7 0.0 1.6 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 EIE89011.1 - 0.035 13.6 0.0 0.088 12.3 0.0 1.6 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type GCR1_C PF12550.3 EIE89012.1 - 1.2e-19 69.9 1.8 3.2e-19 68.5 0.6 2.2 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes Phage_int_SAM_1 PF02899.12 EIE89012.1 - 0.058 13.5 0.0 6.8 6.9 0.0 2.6 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain DDE_3 PF13358.1 EIE89014.1 - 1.7e-19 70.0 0.0 1.9e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.14 EIE89014.1 - 0.00046 19.4 0.1 0.00049 19.3 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease AAA_28 PF13521.1 EIE89014.1 - 0.044 13.7 0.1 0.059 13.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain HTH_Tnp_Tc3_2 PF01498.13 EIE89015.1 - 1.4e-14 53.8 1.1 2.4e-14 53.1 0.3 1.7 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 EIE89015.1 - 3.1e-05 24.0 1.2 4.2e-05 23.6 0.1 1.7 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.1 EIE89015.1 - 4e-05 24.3 0.5 0.011 16.4 0.0 3.0 3 0 0 3 3 3 1 Homeodomain-like domain HTH_38 PF13936.1 EIE89015.1 - 8.8e-05 21.9 0.0 0.00038 19.9 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_7 PF02796.10 EIE89015.1 - 0.0012 18.7 0.8 0.17 11.7 0.0 2.9 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase HTH_23 PF13384.1 EIE89015.1 - 0.0019 17.7 0.0 0.022 14.4 0.0 2.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_21 PF13276.1 EIE89015.1 - 0.0075 16.2 0.0 0.03 14.3 0.0 1.9 2 0 0 2 2 2 1 HTH-like domain Sigma70_r4_2 PF08281.7 EIE89015.1 - 0.026 13.9 0.1 0.12 11.9 0.0 2.0 2 0 0 2 2 2 0 Sigma-70, region 4 CPSase_L_D3 PF02787.14 EIE89015.1 - 0.043 13.5 0.1 0.13 12.0 0.0 1.7 2 0 0 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain DUF2642 PF10842.3 EIE89015.1 - 0.052 13.0 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2642) HTH_28 PF13518.1 EIE89015.1 - 0.082 12.9 0.5 0.25 11.4 0.0 2.0 2 1 0 2 2 2 0 Helix-turn-helix domain GerE PF00196.14 EIE89015.1 - 0.12 11.6 0.0 4.4 6.7 0.0 2.4 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family DDE_3 PF13358.1 EIE89016.1 - 3.9e-16 59.1 0.1 5.8e-16 58.5 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE89016.1 - 0.0029 17.7 0.0 0.0049 16.9 0.0 1.5 1 1 0 1 1 1 1 Integrase core domain zf-trcl PF13451.1 EIE89016.1 - 1.9 8.1 4.9 0.92 9.1 0.3 2.4 2 0 0 2 2 2 0 Probable zinc-binding domain DDE_3 PF13358.1 EIE89017.1 - 8.6e-21 74.2 0.3 1.4e-20 73.4 0.2 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE89017.1 - 3.7e-06 26.9 0.5 9.1e-06 25.6 0.1 1.9 2 0 0 2 2 2 1 Transposase rve PF00665.21 EIE89017.1 - 0.0048 16.9 0.1 0.015 15.4 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain HTH_Tnp_Tc3_2 PF01498.13 EIE89018.1 - 7.8e-05 22.6 0.9 0.00013 21.9 0.2 1.8 2 1 0 2 2 2 1 Transposase HTH_23 PF13384.1 EIE89018.1 - 0.082 12.5 0.0 0.9 9.2 0.0 2.3 2 0 0 2 2 2 0 Homeodomain-like domain DDE_3 PF13358.1 EIE89019.1 - 3.8e-33 114.3 0.0 5.4e-33 113.8 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_ISAZ013 PF07592.6 EIE89019.1 - 0.0016 17.2 0.0 0.55 8.9 0.0 2.1 2 0 0 2 2 2 2 Rhodopirellula transposase DDE domain rve PF00665.21 EIE89019.1 - 0.0075 16.3 0.0 0.014 15.4 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain DDE_1 PF03184.14 EIE89019.1 - 0.073 12.1 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease MTS PF05175.9 EIE89019.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain HTH_Tnp_Tc3_2 PF01498.13 EIE89022.1 - 5.4e-15 55.2 0.6 8.4e-15 54.5 0.2 1.5 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.1 EIE89022.1 - 2.1e-05 24.2 0.9 0.00052 19.7 0.1 2.2 1 1 1 2 2 2 2 DDE superfamily endonuclease HTH_29 PF13551.1 EIE89022.1 - 0.028 14.5 0.1 0.062 13.4 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn helix DDE_3 PF13358.1 EIE89023.1 - 9.8e-24 83.7 0.1 1.5e-23 83.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE89023.1 - 8.3e-12 44.9 0.4 3.5e-11 43.0 0.1 2.1 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.1 EIE89023.1 - 1.6e-05 24.3 0.0 0.0007 19.1 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.1 EIE89023.1 - 0.00011 22.0 0.0 0.0021 17.9 0.0 2.7 3 0 0 3 3 3 1 Helix-turn-helix domain DDE_Tnp_ISAZ013 PF07592.6 EIE89023.1 - 0.00021 20.1 0.0 0.029 13.1 0.0 2.1 2 0 0 2 2 2 2 Rhodopirellula transposase DDE domain HTH_29 PF13551.1 EIE89023.1 - 0.00039 20.5 0.0 0.0015 18.6 0.0 2.0 1 1 0 1 1 1 1 Winged helix-turn helix HTH_11 PF08279.7 EIE89023.1 - 0.00081 18.9 0.1 0.016 14.8 0.0 2.3 2 0 0 2 2 2 1 HTH domain PAX PF00292.13 EIE89023.1 - 0.0014 18.2 0.0 0.003 17.2 0.0 1.5 1 0 0 1 1 1 1 'Paired box' domain rve PF00665.21 EIE89023.1 - 0.002 18.1 0.0 0.0044 17.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Trp_repressor PF01371.14 EIE89023.1 - 0.0036 17.2 0.0 0.0097 15.8 0.0 1.7 1 0 0 1 1 1 1 Trp repressor protein HTH_26 PF13443.1 EIE89023.1 - 0.015 15.5 0.1 0.22 11.7 0.0 2.7 3 0 0 3 3 2 0 Cro/C1-type HTH DNA-binding domain HTH_7 PF02796.10 EIE89023.1 - 0.019 14.7 2.1 0.46 10.3 0.1 3.1 3 1 0 3 3 3 0 Helix-turn-helix domain of resolvase HTH_Tnp_ISL3 PF13542.1 EIE89023.1 - 0.04 13.1 0.0 0.3 10.3 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 CENP-B_N PF04218.8 EIE89023.1 - 0.047 13.1 0.0 0.38 10.1 0.0 2.2 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain UPF0258 PF06789.7 EIE89023.1 - 0.068 13.2 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0258) LacI PF00356.16 EIE89023.1 - 0.11 12.1 0.0 6.2 6.5 0.0 2.6 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family HTH_38 PF13936.1 EIE89023.1 - 0.14 11.7 0.1 0.54 9.8 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain Leader_Erm PF08253.6 EIE89025.1 - 0.33 10.4 0.3 0.33 10.4 0.2 2.1 2 0 0 2 2 2 0 Erm Leader peptide DDE_3 PF13358.1 EIE89026.1 - 1.7e-15 57.0 0.2 2.4e-15 56.5 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE89026.1 - 0.0045 17.0 0.0 0.0077 16.3 0.0 1.5 1 1 0 1 1 1 1 Integrase core domain HTH_Tnp_Tc3_2 PF01498.13 EIE89029.1 - 2.1e-05 24.4 0.2 2.7e-05 24.1 0.1 1.2 1 0 0 1 1 1 1 Transposase DDE_Tnp_ISAZ013 PF07592.6 EIE89029.1 - 0.11 11.1 0.1 0.11 11.1 0.1 1.0 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain HTH_Tnp_Tc3_2 PF01498.13 EIE89030.1 - 9.6e-07 28.7 6.2 3.2e-06 27.1 0.3 2.4 1 1 1 2 2 2 1 Transposase HTH_21 PF13276.1 EIE89030.1 - 0.0073 16.2 1.4 1.7 8.7 0.0 2.6 3 0 0 3 3 3 2 HTH-like domain DDE_3 PF13358.1 EIE89030.1 - 0.028 14.1 0.0 0.069 12.8 0.0 1.6 1 0 0 1 1 1 0 DDE superfamily endonuclease Sigma70_r1_2 PF00140.15 EIE89030.1 - 0.05 13.2 0.2 0.092 12.4 0.1 1.4 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 Trp_repressor PF01371.14 EIE89030.1 - 0.12 12.3 0.0 0.31 11.0 0.0 1.7 1 0 0 1 1 1 0 Trp repressor protein HTH_Tnp_Tc3_2 PF01498.13 EIE89031.1 - 2e-16 59.7 0.8 2.1e-15 56.5 0.2 2.4 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 EIE89031.1 - 1.7e-06 28.1 1.6 2.1e-06 27.8 0.2 1.8 2 0 0 2 2 2 1 Winged helix-turn helix HTH_38 PF13936.1 EIE89031.1 - 1.1e-05 24.8 0.0 3e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.1 EIE89031.1 - 4.8e-05 22.8 0.6 0.0017 17.9 0.0 2.9 3 0 0 3 3 3 1 Homeodomain-like domain HTH_32 PF13565.1 EIE89031.1 - 0.0001 23.0 5.3 0.0092 16.7 0.1 3.3 3 1 0 3 3 3 1 Homeodomain-like domain HTH_7 PF02796.10 EIE89031.1 - 0.00013 21.7 1.2 0.013 15.3 0.0 2.8 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase HTH_21 PF13276.1 EIE89031.1 - 0.00038 20.3 0.0 0.04 13.9 0.0 2.4 2 0 0 2 2 2 1 HTH-like domain HTH_28 PF13518.1 EIE89031.1 - 0.00099 19.0 0.0 0.0086 16.0 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.7 EIE89031.1 - 0.0036 16.7 1.1 0.024 14.0 0.0 2.6 3 1 0 3 3 3 1 Sigma-70, region 4 HTH_Tnp_4 PF13613.1 EIE89031.1 - 0.013 15.0 0.5 0.032 13.7 0.1 1.8 2 0 0 2 2 2 0 Helix-turn-helix of DDE superfamily endonuclease LacI PF00356.16 EIE89031.1 - 0.018 14.6 1.0 0.76 9.4 0.1 2.4 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family CPSase_L_D3 PF02787.14 EIE89031.1 - 0.028 14.1 0.0 0.083 12.6 0.0 1.7 2 0 0 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain HTH_17 PF12728.2 EIE89031.1 - 0.039 14.2 0.7 6.4 7.1 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain GerE PF00196.14 EIE89031.1 - 0.042 13.1 0.0 1.2 8.5 0.0 2.3 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family Sigma70_r4 PF04545.11 EIE89031.1 - 0.047 13.0 0.1 0.34 10.2 0.0 2.3 3 0 0 3 3 3 0 Sigma-70, region 4 HTH_Tnp_ISL3 PF13542.1 EIE89031.1 - 0.12 11.5 3.7 7.5 5.8 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 HTH_40 PF14493.1 EIE89031.1 - 0.13 12.5 0.1 0.36 11.0 0.0 1.8 1 1 0 1 1 1 0 Helix-turn-helix domain DUF2642 PF10842.3 EIE89031.1 - 0.13 11.7 0.0 0.32 10.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2642) HTH_36 PF13730.1 EIE89031.1 - 0.14 12.3 0.0 3.8 7.7 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.13 EIE89032.1 - 6.3e-12 45.3 0.7 1.1e-11 44.5 0.1 1.8 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 EIE89032.1 - 4.4e-05 23.5 0.3 7.9e-05 22.7 0.2 1.4 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EIE89032.1 - 0.00067 19.2 0.0 0.0017 17.9 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_7 PF02796.10 EIE89032.1 - 0.00084 19.1 0.5 0.047 13.5 0.1 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase Mod_r PF07200.8 EIE89033.1 - 0.00026 20.9 0.1 0.00051 19.9 0.1 1.4 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Matrilin_ccoil PF10393.4 EIE89033.1 - 0.023 14.0 0.2 0.05 12.9 0.2 1.5 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin Reo_sigmaC PF04582.7 EIE89033.1 - 0.068 12.3 1.1 0.1 11.7 0.8 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein TMF_DNA_bd PF12329.3 EIE89033.1 - 0.14 11.9 4.0 1.5 8.6 1.4 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding LacI PF00356.16 EIE89033.1 - 0.39 10.3 2.5 1.2 8.7 0.0 2.7 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family Exo_endo_phos_2 PF14529.1 EIE89034.1 - 4e-19 68.3 0.0 6.7e-19 67.6 0.0 1.4 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EIE89034.1 - 1.4e-05 25.1 0.0 2.4e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RVT_1 PF00078.22 EIE89035.1 - 3.2e-29 101.8 0.0 4.9e-29 101.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Transposase_21 PF02992.9 EIE89036.1 - 4.9e-23 81.4 0.1 4.9e-23 81.4 0.1 1.7 2 0 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.1 EIE89036.1 - 3.3e-05 23.3 0.3 7.1e-05 22.2 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) DDE_3 PF13358.1 EIE89037.1 - 3.9e-17 62.3 0.1 8.1e-17 61.3 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE89037.1 - 7.8e-09 35.4 0.9 2.1e-08 34.1 0.5 1.8 1 1 0 1 1 1 1 Transposase rve PF00665.21 EIE89038.1 - 4.5e-17 62.2 0.0 1e-16 61.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE89038.1 - 5.6e-17 61.8 0.1 1.3e-16 60.6 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE89038.1 - 3.4e-09 36.2 0.5 7.7e-09 35.1 0.3 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.1 EIE89038.1 - 1.5e-07 31.8 0.0 3.9e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 EIE89038.1 - 6.7e-07 29.1 0.1 2.6e-06 27.2 0.0 2.0 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EIE89038.1 - 0.00062 19.5 0.0 0.0014 18.4 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.5 EIE89038.1 - 0.007 15.9 0.1 0.058 12.9 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease Tudor-knot PF11717.3 EIE89038.1 - 0.018 14.7 0.2 0.059 13.0 0.1 1.8 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain Lzipper-MIP1 PF14389.1 EIE89040.1 - 0.0038 17.3 0.4 0.011 15.7 0.3 1.8 1 0 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 IncA PF04156.9 EIE89040.1 - 0.14 11.7 1.1 0.24 10.9 0.8 1.4 1 0 0 1 1 1 0 IncA protein SRR PF07709.6 EIE89040.1 - 0.17 12.2 4.4 4.9 7.7 0.0 3.6 3 0 0 3 3 3 0 Seven Residue Repeat ChaB PF06150.7 EIE89040.1 - 0.21 11.4 0.2 0.21 11.4 0.1 2.2 3 0 0 3 3 3 0 ChaB DDE_3 PF13358.1 EIE89041.1 - 4.3e-21 75.2 0.4 5.9e-21 74.7 0.3 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EIE89043.1 - 1.4e-19 70.2 0.0 2.4e-19 69.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE89043.1 - 4.5e-08 33.0 3.3 5.2e-08 32.8 0.1 2.4 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 EIE89043.1 - 0.0012 19.0 1.5 0.004 17.2 1.0 2.0 1 1 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_ISL3 PF13542.1 EIE89043.1 - 0.047 12.8 0.8 0.047 12.8 0.5 2.4 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 rve PF00665.21 EIE89043.1 - 0.073 13.1 0.1 0.21 11.7 0.0 1.9 2 0 0 2 2 2 0 Integrase core domain HTH_21 PF13276.1 EIE89043.1 - 0.3 11.1 2.7 1.3 9.0 0.0 2.7 3 0 0 3 3 3 0 HTH-like domain HTH_23 PF13384.1 EIE89043.1 - 0.43 10.3 2.9 3.8 7.2 0.2 2.6 2 0 0 2 2 2 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.13 EIE89044.1 - 6.4e-05 22.9 0.7 6.4e-05 22.9 0.5 1.8 1 1 0 1 1 1 1 Transposase Sigma70_r1_2 PF00140.15 EIE89044.1 - 0.0036 16.9 0.1 0.0067 16.0 0.1 1.4 1 0 0 1 1 1 1 Sigma-70 factor, region 1.2 DDE_3 PF13358.1 EIE89044.1 - 0.0049 16.6 0.0 0.01 15.5 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE89045.1 - 5.9e-07 29.4 0.1 3.7e-06 26.9 0.0 2.1 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.1 EIE89045.1 - 9.9e-06 25.0 0.0 5.3e-05 22.7 0.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.1 EIE89045.1 - 0.0015 18.4 0.1 0.018 15.0 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_38 PF13936.1 EIE89045.1 - 0.0057 16.1 0.3 0.012 15.1 0.2 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4 PF04545.11 EIE89045.1 - 0.032 13.5 0.0 0.063 12.5 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 Trp_repressor PF01371.14 EIE89045.1 - 0.056 13.3 0.1 0.1 12.5 0.1 1.3 1 0 0 1 1 1 0 Trp repressor protein HTH_Tnp_ISL3 PF13542.1 EIE89045.1 - 0.1 11.7 0.0 0.2 10.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 DUF2521 PF10730.4 EIE89046.1 - 0.072 12.9 0.2 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2521) Zn_protease PF05618.6 EIE89046.1 - 0.11 12.1 2.0 0.15 11.7 1.4 1.1 1 0 0 1 1 1 0 Putative ATP-dependant zinc protease Pkinase PF00069.20 EIE89051.1 - 4.1e-57 193.2 0.0 5.5e-55 186.3 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE89051.1 - 5.2e-22 78.1 0.0 1.5e-21 76.6 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE89051.1 - 4.7e-10 38.9 0.0 4e-09 35.8 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EIE89051.1 - 1.3e-06 27.6 0.0 2e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIE89051.1 - 4e-06 26.7 0.0 5.4e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EIE89051.1 - 0.0041 16.7 0.0 0.0062 16.1 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.4 EIE89051.1 - 0.041 13.2 0.0 0.064 12.5 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Med31 PF05669.7 EIE89052.1 - 0.1 12.3 0.4 0.45 10.2 0.1 1.8 1 1 1 2 2 2 0 SOH1 NeuB PF03102.9 EIE89052.1 - 0.13 11.4 0.5 0.13 11.3 0.3 1.0 1 0 0 1 1 1 0 NeuB family VHS PF00790.14 EIE89053.1 - 3.4e-17 62.3 0.4 3.4e-17 62.3 0.3 2.5 2 1 1 3 3 3 1 VHS domain GAT PF03127.9 EIE89053.1 - 2e-06 27.6 3.0 2e-06 27.6 2.1 3.5 3 2 0 3 3 3 1 GAT domain Tom7 PF08038.7 EIE89054.1 - 2.4e-16 58.8 0.3 2.8e-16 58.6 0.2 1.1 1 0 0 1 1 1 1 TOM7 family Plant_tran PF04827.9 EIE89056.1 - 0.03 13.6 0.0 0.03 13.6 0.0 1.1 1 0 0 1 1 1 0 Plant transposon protein SAC3_GANP PF03399.11 EIE89057.1 - 1.3e-49 168.5 2.3 1.3e-49 168.5 1.6 2.0 2 0 0 2 2 2 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family HTH_Tnp_Tc3_2 PF01498.13 EIE89059.1 - 2.1e-10 40.4 2.5 1.7e-09 37.5 0.9 2.2 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.1 EIE89059.1 - 0.00017 21.0 0.1 0.00042 19.8 0.0 1.6 2 0 0 2 2 1 1 Homeodomain-like domain HTH_IclR PF09339.5 EIE89059.1 - 0.00027 20.4 0.0 0.00058 19.3 0.0 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_11 PF08279.7 EIE89059.1 - 0.0003 20.3 0.0 0.0007 19.1 0.0 1.6 1 0 0 1 1 1 1 HTH domain HTH_7 PF02796.10 EIE89059.1 - 0.00055 19.7 0.3 0.021 14.6 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_32 PF13565.1 EIE89059.1 - 0.0012 19.5 1.6 1.1 10.0 0.0 2.5 2 1 0 2 2 2 2 Homeodomain-like domain HTH_38 PF13936.1 EIE89059.1 - 0.0027 17.2 0.0 0.0058 16.1 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.1 EIE89059.1 - 0.0029 17.7 0.1 0.033 14.3 0.0 2.0 2 0 0 2 2 2 1 Winged helix-turn helix Sigma70_r4_2 PF08281.7 EIE89059.1 - 0.006 16.0 0.0 0.012 15.0 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_AsnC-type PF13404.1 EIE89059.1 - 0.0068 15.9 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_36 PF13730.1 EIE89059.1 - 0.0081 16.2 0.0 0.096 12.8 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_24 PF13412.1 EIE89059.1 - 0.017 14.4 0.0 0.036 13.4 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Sigma70_r4 PF04545.11 EIE89059.1 - 0.018 14.3 0.0 0.033 13.4 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_17 PF12728.2 EIE89059.1 - 0.02 15.1 0.0 0.037 14.2 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain UPF0122 PF04297.9 EIE89059.1 - 0.021 14.8 0.1 0.038 14.0 0.0 1.3 1 0 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like GerE PF00196.14 EIE89059.1 - 0.038 13.2 0.0 0.071 12.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family Terminase_5 PF06056.7 EIE89059.1 - 0.04 13.4 0.0 0.087 12.3 0.0 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) HTH_Tnp_4 PF13613.1 EIE89059.1 - 0.059 12.9 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_Crp_2 PF13545.1 EIE89059.1 - 0.077 12.7 0.0 0.22 11.3 0.0 1.7 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_6 PF01418.12 EIE89059.1 - 0.08 12.6 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family Trp_repressor PF01371.14 EIE89059.1 - 0.082 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Trp repressor protein HTH_28 PF13518.1 EIE89059.1 - 0.1 12.6 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_22 PF13309.1 EIE89059.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 HTH domain HTH_30 PF13556.1 EIE89059.1 - 0.12 12.0 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain MarR_2 PF12802.2 EIE89059.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 MarR family ABC2_membrane PF01061.19 EIE89061.1 - 6.8e-88 293.2 62.6 1.9e-47 161.1 15.4 3.2 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 EIE89061.1 - 4.6e-36 124.1 0.0 1.4e-20 73.9 0.0 2.7 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EIE89061.1 - 1.1e-19 70.0 0.1 9.8e-19 66.9 0.0 2.7 2 0 0 2 2 2 1 CDR ABC transporter ABC_trans_N PF14510.1 EIE89061.1 - 2e-12 47.0 0.1 4.9e-12 45.7 0.1 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal ABC2_membrane_3 PF12698.2 EIE89061.1 - 1.1e-10 41.0 54.5 3.1e-08 33.0 15.3 3.0 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 EIE89061.1 - 8.1e-06 25.9 0.8 0.14 12.0 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 EIE89061.1 - 0.00013 22.0 0.1 0.11 12.6 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EIE89061.1 - 0.00022 20.7 0.0 0.0056 16.1 0.0 2.8 3 0 0 3 3 3 1 AAA domain DUF258 PF03193.11 EIE89061.1 - 0.00031 19.9 0.1 0.0037 16.4 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EIE89061.1 - 0.0012 18.3 0.3 0.0063 16.0 0.1 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain cobW PF02492.14 EIE89061.1 - 0.0018 17.7 0.0 0.029 13.8 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 EIE89061.1 - 0.0032 17.3 0.1 0.12 12.2 0.0 2.9 2 1 0 2 2 2 1 AAA domain UPF0079 PF02367.12 EIE89061.1 - 0.0062 16.1 1.3 0.79 9.3 0.1 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA PF00004.24 EIE89061.1 - 0.013 15.7 0.0 1.2 9.3 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EIE89061.1 - 0.019 15.2 0.1 0.43 10.8 0.0 2.9 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.7 EIE89061.1 - 0.02 14.0 0.0 1.5 7.8 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_17 PF13207.1 EIE89061.1 - 0.031 15.0 0.0 0.65 10.8 0.0 2.9 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 EIE89061.1 - 0.033 14.0 0.0 0.22 11.4 0.0 2.4 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_19 PF13245.1 EIE89061.1 - 0.047 13.4 0.6 3.8 7.3 0.3 2.5 2 0 0 2 2 2 0 Part of AAA domain AAA_16 PF13191.1 EIE89061.1 - 0.049 13.6 1.5 0.47 10.4 0.2 2.6 2 1 0 2 2 2 0 AAA ATPase domain Miro PF08477.8 EIE89061.1 - 0.074 13.5 0.0 9.7 6.7 0.0 2.9 2 0 0 2 2 2 0 Miro-like protein AAA_28 PF13521.1 EIE89061.1 - 0.2 11.6 2.2 0.16 11.8 0.1 1.9 2 0 0 2 2 1 0 AAA domain AAA_30 PF13604.1 EIE89061.1 - 0.26 10.8 0.2 4.8 6.7 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EIE89061.1 - 1.5 9.1 9.9 0.71 10.1 0.1 3.0 3 0 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.13 EIE89061.1 - 2.2 7.6 3.6 8.1 5.8 0.1 2.9 3 0 0 3 3 3 0 FtsK/SpoIIIE family Aft1_OSA PF11785.3 EIE89062.1 - 1.4e-05 25.4 0.3 2.6e-05 24.6 0.2 1.4 1 0 0 1 1 1 1 Aft1 osmotic stress response (OSM) domain Paramyxo_PNT PF13825.1 EIE89063.1 - 0.37 9.9 1.6 0.51 9.4 1.1 1.2 1 0 0 1 1 1 0 Paramyxovirus structural protein V/P N-terminus Peptidase_M24 PF00557.19 EIE89064.1 - 2.1e-20 73.2 0.0 2.8e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C2H2 PF00096.21 EIE89065.1 - 2.3e-09 37.0 10.0 0.00011 22.3 0.4 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIE89065.1 - 2.8e-08 33.5 8.4 0.00029 20.9 0.6 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EIE89065.1 - 7.1e-06 26.0 5.3 0.0095 16.1 0.0 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-Di19 PF05605.7 EIE89065.1 - 0.003 17.6 0.9 0.003 17.6 0.6 2.6 2 1 1 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-Sec23_Sec24 PF04810.10 EIE89065.1 - 0.0047 16.4 0.2 0.2 11.2 0.0 2.3 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger zf-H2C2_5 PF13909.1 EIE89065.1 - 0.0087 16.2 0.9 0.0087 16.2 0.6 2.9 3 0 0 3 3 3 2 C2H2-type zinc-finger domain C1_4 PF07975.7 EIE89065.1 - 0.011 15.6 2.1 1.4 8.9 0.2 2.5 2 0 0 2 2 2 0 TFIIH C1-like domain zf-C2H2_jaz PF12171.3 EIE89065.1 - 0.036 14.1 13.0 0.12 12.5 0.6 2.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Zn_Tnp_IS1595 PF12760.2 EIE89065.1 - 0.043 13.6 1.4 0.043 13.6 1.0 1.8 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Endonuclease_7 PF02945.10 EIE89065.1 - 0.068 12.8 9.2 0.04 13.6 3.2 2.3 2 1 0 2 2 2 0 Recombination endonuclease VII Rad50_zn_hook PF04423.9 EIE89065.1 - 0.1 12.1 0.6 3.9 7.0 0.1 2.3 2 0 0 2 2 2 0 Rad50 zinc hook motif Elf1 PF05129.8 EIE89065.1 - 0.21 11.3 3.8 3.4 7.4 0.3 2.3 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-met PF12874.2 EIE89065.1 - 0.23 11.6 0.3 0.23 11.6 0.2 2.7 2 1 0 2 2 2 0 Zinc-finger of C2H2 type zf-nanos PF05741.8 EIE89065.1 - 0.42 10.6 0.2 0.42 10.6 0.1 2.4 3 0 0 3 3 3 0 Nanos RNA binding domain Enterotoxin_ST PF02048.11 EIE89065.1 - 0.51 10.6 3.9 12 6.2 0.1 2.7 3 0 0 3 3 2 0 Heat-stable enterotoxin ST zf-CHY PF05495.7 EIE89065.1 - 0.91 9.7 10.3 2.1 8.5 2.9 2.5 2 1 0 2 2 2 0 CHY zinc finger zf-C2H2_2 PF12756.2 EIE89065.1 - 1.4 9.0 13.1 0.84 9.7 1.1 3.1 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) WD40 PF00400.27 EIE89066.1 - 1.1e-42 142.3 15.7 2.1e-10 40.0 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 EIE89066.1 - 1.5e-05 24.7 0.2 0.13 11.9 0.0 3.2 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 EIE89066.1 - 0.005 16.3 0.0 0.075 12.4 0.0 2.4 2 1 0 2 2 2 1 PQQ-like domain Nup160 PF11715.3 EIE89066.1 - 0.0076 14.4 0.3 0.043 11.9 0.1 2.1 1 1 2 3 3 3 1 Nucleoporin Nup120/160 Polysacc_deac_1 PF01522.16 EIE89067.1 - 0.021 14.4 0.1 0.085 12.4 0.0 1.9 2 0 0 2 2 2 0 Polysaccharide deacetylase LigB PF02900.13 EIE89068.1 - 1.3e-21 76.8 0.1 1.7e-18 66.6 0.0 2.1 1 1 1 2 2 2 2 Catalytic LigB subunit of aromatic ring-opening dioxygenase DAO PF01266.19 EIE89069.1 - 2.2e-47 161.7 0.0 2.9e-47 161.3 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EIE89069.1 - 3e-10 39.5 0.9 0.0004 19.3 0.3 2.1 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.2 EIE89069.1 - 5.5e-09 35.5 1.2 6.5e-06 25.4 0.3 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EIE89069.1 - 0.001 18.1 0.0 0.32 9.9 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 EIE89069.1 - 0.0014 18.5 0.3 0.0088 15.9 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EIE89069.1 - 0.0019 17.0 0.2 0.081 11.7 0.1 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 EIE89069.1 - 0.013 15.4 0.5 0.059 13.4 0.5 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain GDI PF00996.13 EIE89069.1 - 0.03 12.6 0.4 1.1 7.4 0.1 2.3 2 1 0 2 2 2 0 GDP dissociation inhibitor 3HCDH_N PF02737.13 EIE89069.1 - 0.034 13.7 0.1 0.07 12.7 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.22 EIE89069.1 - 0.041 14.2 1.0 0.22 11.9 0.2 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EIE89069.1 - 0.042 12.9 0.4 0.14 11.2 0.1 1.9 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.9 EIE89069.1 - 0.044 12.2 0.3 0.096 11.1 0.2 1.5 1 0 0 1 1 1 0 HI0933-like protein DinI PF06183.8 EIE89069.1 - 0.066 13.2 0.0 4.7 7.3 0.0 3.2 3 0 0 3 3 3 0 DinI-like family K_oxygenase PF13434.1 EIE89069.1 - 0.075 11.9 0.1 0.93 8.3 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) SDA1 PF05285.7 EIE89070.1 - 0.00058 19.2 22.9 0.00058 19.2 15.9 1.6 2 0 0 2 2 2 1 SDA1 EF-hand_7 PF13499.1 EIE89071.1 - 2.1e-14 53.4 3.4 2.1e-14 53.4 2.4 2.4 1 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EIE89071.1 - 3.8e-13 47.6 4.1 0.00014 20.8 0.0 3.5 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 EIE89071.1 - 6.4e-11 41.1 4.8 9.9e-05 21.9 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.1 EIE89071.1 - 5.1e-09 35.0 1.2 0.001 18.3 0.0 3.4 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 EIE89071.1 - 4.9e-06 26.0 9.0 0.011 15.3 2.4 2.8 1 1 1 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EIE89071.1 - 0.00072 19.5 1.8 0.0016 18.4 1.0 1.7 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EIE89071.1 - 0.025 14.2 6.8 0.32 10.7 0.7 3.0 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand Leuk-A4-hydro_C PF09127.6 EIE89071.1 - 0.058 12.9 0.1 0.087 12.4 0.1 1.3 1 0 0 1 1 1 0 Leukotriene A4 hydrolase, C-terminal Nse4-Nse3_bdg PF15412.1 EIE89071.1 - 0.067 13.0 0.1 0.15 11.8 0.1 1.6 1 0 0 1 1 1 0 Binding domain of Nse4/EID3 to Nse3-MAGE Abhydrolase_6 PF12697.2 EIE89072.1 - 4.7e-12 46.2 3.4 1.7e-11 44.4 2.3 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIE89072.1 - 1.2e-08 34.8 0.0 1.9e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF4063 PF13272.1 EIE89072.1 - 0.089 12.6 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4063) Abhydrolase_1 PF00561.15 EIE89072.1 - 0.11 12.0 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold LAG1-DNAbind PF09271.6 EIE89073.1 - 5.3e-20 72.3 1.5 6.3e-16 59.1 0.3 2.9 2 1 0 2 2 2 1 LAG1, DNA binding BTD PF09270.5 EIE89073.1 - 7.1e-19 68.1 0.0 1.4e-18 67.1 0.0 1.5 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain MPC PF03650.8 EIE89074.1 - 5e-21 74.8 0.2 5.8e-21 74.6 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) MFS_1 PF07690.11 EIE89075.1 - 4.7e-35 120.9 42.3 3.8e-21 75.1 16.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIE89075.1 - 3.2e-10 39.2 41.2 1.7e-07 30.1 14.2 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter DUF2956 PF11169.3 EIE89075.1 - 0.12 12.3 0.4 1.1 9.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) Cytomega_UL84 PF06284.6 EIE89075.1 - 0.16 10.3 0.1 0.26 9.6 0.1 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein DUF912 PF06024.7 EIE89075.1 - 1.2 9.2 6.6 2.1 8.4 0.1 3.3 2 1 1 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Band_7 PF01145.20 EIE89076.1 - 2.1e-23 83.1 3.5 3e-23 82.6 2.4 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Cyclin PF08613.6 EIE89077.1 - 1.4e-11 45.0 0.2 1.6e-11 44.8 0.1 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EIE89077.1 - 4.6e-10 39.1 0.2 7.7e-10 38.4 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain MS_channel PF00924.13 EIE89078.1 - 1.2e-13 50.8 0.1 1.2e-13 50.8 0.1 1.6 2 0 0 2 2 2 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 EIE89078.1 - 7e-06 24.9 0.0 1.7e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.1 EIE89078.1 - 8.6e-05 21.7 0.1 0.00023 20.3 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 EIE89078.1 - 0.00014 21.4 0.0 0.00038 20.0 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.1 EIE89078.1 - 0.00038 20.5 0.3 0.001 19.1 0.0 1.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.1 EIE89078.1 - 0.09 12.4 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair NAD_Gly3P_dh_N PF01210.18 EIE89079.1 - 1.4e-50 171.1 0.0 1.7e-50 170.8 0.0 1.1 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 EIE89079.1 - 1.3e-08 34.6 0.3 2.3e-08 33.8 0.2 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.12 EIE89079.1 - 0.11 12.8 0.3 15 6.0 0.0 2.6 2 1 1 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent CDP-OH_P_transf PF01066.16 EIE89080.1 - 2.6e-14 53.3 3.7 2.6e-14 53.3 2.6 2.1 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase PCI PF01399.22 EIE89081.1 - 3.6e-20 72.2 0.1 2.1e-19 69.7 0.1 2.1 2 0 0 2 2 2 1 PCI domain TPR_12 PF13424.1 EIE89081.1 - 0.079 12.9 14.5 0.037 13.9 5.6 2.6 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 EIE89081.1 - 0.46 10.5 5.5 0.39 10.7 1.3 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 EIE89081.1 - 0.81 10.0 6.7 4.7 7.6 2.7 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat Arf PF00025.16 EIE89083.1 - 4.8e-77 257.1 0.1 5.4e-77 256.9 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EIE89083.1 - 5.1e-13 48.7 0.0 5.3e-13 48.6 0.0 1.0 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 EIE89083.1 - 8.8e-13 47.8 0.0 1e-12 47.6 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EIE89083.1 - 3.8e-11 42.5 0.0 4.2e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 EIE89083.1 - 8.2e-11 41.2 1.4 5e-09 35.3 0.2 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 EIE89083.1 - 6.5e-09 36.3 0.0 8.9e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EIE89083.1 - 7.2e-06 25.9 0.0 9.1e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 EIE89083.1 - 0.02 13.9 0.4 0.038 13.0 0.2 1.7 1 1 0 1 1 1 0 6-phosphofructo-2-kinase AAA_33 PF13671.1 EIE89083.1 - 0.072 12.9 0.1 0.12 12.2 0.1 1.7 1 1 0 1 1 1 0 AAA domain GTP_EFTU PF00009.22 EIE89083.1 - 0.084 12.3 0.1 0.37 10.1 0.0 1.8 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain Peptidase_C48 PF02902.14 EIE89084.1 - 7.7e-24 84.5 0.2 7.7e-24 84.5 0.1 2.3 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain RVT_1 PF00078.22 EIE89085.1 - 5e-36 124.0 0.0 1.1e-35 122.9 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.18 EIE89086.1 - 1.8e-05 24.4 10.5 0.0025 17.6 1.0 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 EIE89086.1 - 0.043 13.4 8.2 0.039 13.6 1.3 2.4 2 0 0 2 2 2 0 Zinc knuckle Zn_ribbon_2 PF12674.2 EIE89086.1 - 2.9 8.3 8.2 11 6.4 0.9 2.5 1 1 1 2 2 2 0 Putative zinc ribbon domain PPR_2 PF13041.1 EIE89088.1 - 0.24 11.4 2.3 2.6 8.1 0.1 2.6 2 0 0 2 2 2 0 PPR repeat family PPR PF01535.15 EIE89088.1 - 1.1 9.3 6.5 8.5 6.5 0.1 3.2 3 0 0 3 3 3 0 PPR repeat CobT PF06213.7 EIE89089.1 - 0.00077 18.6 15.4 0.00096 18.3 10.7 1.0 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT RNA_pol_3_Rpc31 PF11705.3 EIE89089.1 - 0.085 12.7 19.1 0.095 12.6 13.2 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF1840 PF08895.6 EIE89089.1 - 0.13 12.3 6.9 0.18 11.8 4.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) PBP_sp32 PF07222.7 EIE89089.1 - 0.15 11.1 14.7 0.19 10.8 10.2 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 CDC45 PF02724.9 EIE89089.1 - 0.18 9.8 10.1 0.18 9.8 7.0 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF1510 PF07423.6 EIE89089.1 - 0.36 10.1 13.8 0.38 10.1 9.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Zip PF02535.17 EIE89089.1 - 0.41 9.5 1.7 0.45 9.4 1.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Spore_coat_CotO PF14153.1 EIE89089.1 - 0.49 9.8 14.4 0.53 9.7 10.0 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Tom37_C PF11801.3 EIE89089.1 - 0.55 10.0 4.8 1.1 9.1 3.4 1.5 1 1 0 1 1 1 0 Tom37 C-terminal domain Paf1 PF03985.8 EIE89089.1 - 0.63 8.7 16.5 0.62 8.7 11.4 1.1 1 0 0 1 1 1 0 Paf1 DDHD PF02862.12 EIE89089.1 - 0.67 9.7 3.8 0.65 9.7 2.6 1.1 1 0 0 1 1 1 0 DDHD domain Dicty_REP PF05086.7 EIE89089.1 - 0.84 7.3 10.6 0.95 7.1 7.4 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Ycf1 PF05758.7 EIE89089.1 - 0.98 7.0 7.3 0.89 7.1 5.1 1.0 1 0 0 1 1 1 0 Ycf1 PTRF_SDPR PF15237.1 EIE89089.1 - 1 8.7 13.1 1.3 8.4 9.1 1.0 1 0 0 1 1 1 0 PTRF/SDPR family Daxx PF03344.10 EIE89089.1 - 1.1 7.7 21.5 1.1 7.6 14.9 1.0 1 0 0 1 1 1 0 Daxx Family VID27 PF08553.5 EIE89089.1 - 1.1 7.3 13.2 1.1 7.3 9.1 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Vfa1 PF08432.5 EIE89089.1 - 1.2 9.1 11.1 1.3 9.0 7.7 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 IncA PF04156.9 EIE89089.1 - 1.2 8.6 11.3 1.3 8.5 7.8 1.1 1 0 0 1 1 1 0 IncA protein DUF162 PF02589.10 EIE89089.1 - 1.3 8.4 4.6 1.5 8.3 3.2 1.0 1 0 0 1 1 1 0 Uncharacterised ACR, YkgG family COG1556 Saw1 PF11561.3 EIE89089.1 - 1.5 8.1 6.7 1.7 8.0 4.6 1.1 1 0 0 1 1 1 0 Single strand annealing-weakened 1 TRAP_alpha PF03896.11 EIE89089.1 - 1.6 7.6 14.5 2 7.3 10.1 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit PPP4R2 PF09184.6 EIE89089.1 - 1.9 7.9 19.2 2.1 7.7 13.3 1.1 1 0 0 1 1 1 0 PPP4R2 Nop14 PF04147.7 EIE89089.1 - 2.5 5.9 22.8 2.6 5.8 15.8 1.0 1 0 0 1 1 1 0 Nop14-like family YqfQ PF14181.1 EIE89089.1 - 2.8 7.9 8.3 3.2 7.7 5.7 1.2 1 0 0 1 1 1 0 YqfQ-like protein NOA36 PF06524.7 EIE89089.1 - 4.1 6.5 9.7 5.2 6.2 6.7 1.2 1 0 0 1 1 1 0 NOA36 protein Radial_spoke PF04712.7 EIE89089.1 - 5.3 5.6 17.5 6.1 5.4 12.1 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein APG6 PF04111.7 EIE89089.1 - 5.5 5.9 15.1 6.3 5.7 10.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 BTV_NS2 PF04514.7 EIE89089.1 - 7.3 5.3 12.5 7.8 5.2 8.7 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 CKAP2_C PF15297.1 EIE89089.1 - 8.3 5.1 16.5 10 4.7 11.1 1.4 1 1 1 2 2 2 0 Cytoskeleton-associated protein 2 C-terminus SAC3_GANP PF03399.11 EIE89091.1 - 1.5e-46 158.5 2.0 2e-46 158.1 1.4 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Exo_endo_phos_2 PF14529.1 EIE89092.1 - 0.0034 16.9 0.0 0.0049 16.4 0.0 1.3 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EIE89092.1 - 0.016 15.1 0.1 0.018 15.0 0.1 1.2 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family CobT PF06213.7 EIE89094.1 - 0.00077 18.6 15.4 0.00096 18.3 10.7 1.0 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT RNA_pol_3_Rpc31 PF11705.3 EIE89094.1 - 0.085 12.7 19.1 0.095 12.6 13.2 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF1840 PF08895.6 EIE89094.1 - 0.13 12.3 6.9 0.18 11.8 4.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) PBP_sp32 PF07222.7 EIE89094.1 - 0.15 11.1 14.7 0.19 10.8 10.2 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 CDC45 PF02724.9 EIE89094.1 - 0.18 9.8 10.1 0.18 9.8 7.0 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF1510 PF07423.6 EIE89094.1 - 0.36 10.1 13.8 0.38 10.1 9.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Zip PF02535.17 EIE89094.1 - 0.41 9.5 1.7 0.45 9.4 1.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Spore_coat_CotO PF14153.1 EIE89094.1 - 0.49 9.8 14.4 0.53 9.7 10.0 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Tom37_C PF11801.3 EIE89094.1 - 0.55 10.0 4.8 1.1 9.1 3.4 1.5 1 1 0 1 1 1 0 Tom37 C-terminal domain Paf1 PF03985.8 EIE89094.1 - 0.63 8.7 16.5 0.62 8.7 11.4 1.1 1 0 0 1 1 1 0 Paf1 DDHD PF02862.12 EIE89094.1 - 0.67 9.7 3.8 0.65 9.7 2.6 1.1 1 0 0 1 1 1 0 DDHD domain Dicty_REP PF05086.7 EIE89094.1 - 0.84 7.3 10.6 0.95 7.1 7.4 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Ycf1 PF05758.7 EIE89094.1 - 0.98 7.0 7.3 0.89 7.1 5.1 1.0 1 0 0 1 1 1 0 Ycf1 PTRF_SDPR PF15237.1 EIE89094.1 - 1 8.7 13.1 1.3 8.4 9.1 1.0 1 0 0 1 1 1 0 PTRF/SDPR family Daxx PF03344.10 EIE89094.1 - 1.1 7.7 21.5 1.1 7.6 14.9 1.0 1 0 0 1 1 1 0 Daxx Family VID27 PF08553.5 EIE89094.1 - 1.1 7.3 13.2 1.1 7.3 9.1 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Vfa1 PF08432.5 EIE89094.1 - 1.2 9.1 11.1 1.3 9.0 7.7 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 IncA PF04156.9 EIE89094.1 - 1.2 8.6 11.3 1.3 8.5 7.8 1.1 1 0 0 1 1 1 0 IncA protein DUF162 PF02589.10 EIE89094.1 - 1.3 8.4 4.6 1.5 8.3 3.2 1.0 1 0 0 1 1 1 0 Uncharacterised ACR, YkgG family COG1556 Saw1 PF11561.3 EIE89094.1 - 1.5 8.1 6.7 1.7 8.0 4.6 1.1 1 0 0 1 1 1 0 Single strand annealing-weakened 1 TRAP_alpha PF03896.11 EIE89094.1 - 1.6 7.6 14.5 2 7.3 10.1 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit PPP4R2 PF09184.6 EIE89094.1 - 1.9 7.9 19.2 2.1 7.7 13.3 1.1 1 0 0 1 1 1 0 PPP4R2 Nop14 PF04147.7 EIE89094.1 - 2.5 5.9 22.8 2.6 5.8 15.8 1.0 1 0 0 1 1 1 0 Nop14-like family YqfQ PF14181.1 EIE89094.1 - 2.8 7.9 8.3 3.2 7.7 5.7 1.2 1 0 0 1 1 1 0 YqfQ-like protein NOA36 PF06524.7 EIE89094.1 - 4.1 6.5 9.7 5.2 6.2 6.7 1.2 1 0 0 1 1 1 0 NOA36 protein Radial_spoke PF04712.7 EIE89094.1 - 5.3 5.6 17.5 6.1 5.4 12.1 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein APG6 PF04111.7 EIE89094.1 - 5.5 5.9 15.1 6.3 5.7 10.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 BTV_NS2 PF04514.7 EIE89094.1 - 7.3 5.3 12.5 7.8 5.2 8.7 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 CKAP2_C PF15297.1 EIE89094.1 - 8.3 5.1 16.5 10 4.7 11.1 1.4 1 1 1 2 2 2 0 Cytoskeleton-associated protein 2 C-terminus zf-CCHC PF00098.18 EIE89095.1 - 4.9e-05 23.0 11.2 0.0039 17.0 0.9 2.3 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 EIE89095.1 - 0.0047 16.5 5.7 0.0089 15.6 0.3 2.4 2 0 0 2 2 2 1 Zinc knuckle RRM_1 PF00076.17 EIE89095.1 - 0.057 13.0 0.0 0.17 11.5 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC_3 PF13917.1 EIE89095.1 - 3.7 7.3 8.2 2.3 7.9 0.1 2.4 1 1 1 2 2 2 0 Zinc knuckle Zn_ribbon_2 PF12674.2 EIE89095.1 - 7.3 7.0 7.4 34 4.8 0.6 2.6 1 1 1 2 2 2 0 Putative zinc ribbon domain RVT_1 PF00078.22 EIE89096.1 - 2.7e-39 134.7 0.0 3.1e-39 134.5 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.1 EIE89097.1 - 0.0018 18.5 0.3 0.0035 17.6 0.2 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase zf-CCHC PF00098.18 EIE89099.1 - 3.3e-05 23.6 9.1 0.0001 22.0 0.4 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 EIE89099.1 - 0.0078 15.8 0.9 0.0078 15.8 0.6 2.3 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_6 PF15288.1 EIE89099.1 - 0.014 15.0 0.4 0.035 13.7 0.2 1.7 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.22 EIE89101.1 - 6.9e-19 68.0 0.5 1.6e-18 66.8 0.1 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Dam PF05869.6 EIE89101.1 - 0.0042 16.5 1.1 0.0052 16.2 0.0 1.7 2 0 0 2 2 2 1 DNA N-6-adenine-methyltransferase (Dam) RVT_3 PF13456.1 EIE89101.1 - 0.1 12.4 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 Reverse transcriptase-like DUF2458 PF10454.4 EIE89103.1 - 0.014 15.3 1.3 0.025 14.4 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2458) ER_lumen_recept PF00810.13 EIE89105.1 - 7.8e-36 123.7 6.2 1.3e-35 123.0 4.3 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor DUF2512 PF10710.4 EIE89105.1 - 0.021 14.2 3.3 0.029 13.8 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2512) PQ-loop PF04193.9 EIE89105.1 - 0.09 12.3 0.3 0.09 12.3 0.2 2.1 3 0 0 3 3 3 0 PQ loop repeat TPR_2 PF07719.12 EIE89107.1 - 3.2e-06 26.6 3.0 0.22 11.5 0.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EIE89107.1 - 6.7e-05 22.3 6.8 0.042 13.4 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EIE89107.1 - 0.00055 19.8 4.0 3.4 7.6 0.1 3.4 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 EIE89107.1 - 0.0007 19.1 4.8 0.032 14.0 0.0 3.9 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 EIE89107.1 - 0.00089 18.8 6.3 0.48 10.0 0.1 3.2 2 1 1 3 3 3 2 TPR repeat TPR_16 PF13432.1 EIE89107.1 - 0.021 15.5 0.1 1.6 9.5 0.0 3.0 2 1 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 EIE89107.1 - 0.043 14.1 0.7 11 6.4 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Acyl-CoA_dh_1 PF00441.19 EIE89108.1 - 4.5e-37 127.4 0.5 7.1e-37 126.8 0.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EIE89108.1 - 1e-21 76.1 0.4 2.6e-21 74.8 0.3 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.23 EIE89108.1 - 1.3e-21 76.1 0.0 2.5e-21 75.2 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.11 EIE89108.1 - 2.1e-17 63.7 0.3 9.3e-17 61.6 0.2 2.1 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain CDP-OH_P_transf PF01066.16 EIE89108.1 - 1.4e-15 57.4 5.6 2.6e-15 56.5 3.4 1.8 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Acyl-CoA_dh_2 PF08028.6 EIE89108.1 - 0.00034 20.8 0.1 0.00061 20.0 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Iso_dh PF00180.15 EIE89109.1 - 1.1e-80 271.1 0.0 1.3e-80 270.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase CDC37_M PF08565.6 EIE89109.1 - 0.08 12.4 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 Cdc37 Hsp90 binding domain GTP_EFTU PF00009.22 EIE89110.1 - 6.7e-47 159.3 0.0 1.2e-46 158.5 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EIE89110.1 - 4.9e-26 90.7 0.1 1.8e-25 88.9 0.1 2.0 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EIE89110.1 - 1.4e-11 44.3 0.2 3.6e-11 43.0 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EIE89110.1 - 0.00021 21.2 0.0 0.00062 19.7 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Mitofilin PF09731.4 EIE89110.1 - 0.0097 14.6 5.4 0.013 14.2 3.7 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein G-alpha PF00503.15 EIE89110.1 - 0.09 11.4 0.1 0.16 10.6 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit Med3 PF11593.3 EIE89110.1 - 7.7 5.6 8.5 11 5.1 5.9 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Not3 PF04065.10 EIE89111.1 - 9.9e-45 152.6 9.4 9.9e-45 152.6 6.5 2.5 3 0 0 3 3 3 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 EIE89111.1 - 3.4e-13 49.6 2.8 3.4e-13 49.6 1.9 2.5 2 1 0 2 2 2 1 NOT2 / NOT3 / NOT5 family DUF605 PF04652.11 EIE89111.1 - 0.0054 16.1 17.4 0.0063 15.9 12.1 1.2 1 0 0 1 1 1 1 Vta1 like DUF572 PF04502.8 EIE89111.1 - 0.044 12.9 20.7 0.067 12.3 14.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) SmpA_OmlA PF04355.8 EIE89111.1 - 0.063 12.9 0.3 0.14 11.7 0.2 1.6 1 0 0 1 1 1 0 SmpA / OmlA family Mucin PF01456.12 EIE89111.1 - 0.074 12.8 24.3 0.12 12.1 16.9 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Dicty_REP PF05086.7 EIE89111.1 - 0.085 10.6 19.1 0.03 12.1 8.3 2.0 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein DUF1192 PF06698.6 EIE89111.1 - 0.46 10.3 4.3 0.24 11.2 0.6 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1192) ABC_tran_2 PF12848.2 EIE89111.1 - 1.3 8.8 5.8 0.82 9.5 2.1 2.1 2 0 0 2 2 2 0 ABC transporter Ribosomal_L12 PF00542.14 EIE89112.1 - 7.5e-22 77.1 12.5 1.6e-21 76.0 7.2 2.0 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain DUF2267 PF10025.4 EIE89112.1 - 0.0034 17.4 0.4 0.0071 16.3 0.3 1.8 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2267) Ribosomal_60s PF00428.14 EIE89112.1 - 1.2 9.5 12.4 0.15 12.5 3.1 2.5 1 1 0 2 2 2 0 60s Acidic ribosomal protein UCH PF00443.24 EIE89113.1 - 3.9e-39 134.3 21.3 1.1e-38 132.9 14.8 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.1 EIE89113.1 - 4.6e-11 41.9 2.5 1.6e-08 33.8 0.3 3.1 3 0 0 3 3 3 2 A repeated domain in UCH-protein UCH_1 PF13423.1 EIE89113.1 - 2.2e-10 40.4 14.4 1.4e-08 34.5 8.7 3.5 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase PUB PF09409.5 EIE89113.1 - 1e-05 25.1 0.3 7.2e-05 22.4 0.1 2.6 2 0 0 2 2 2 1 PUB domain Atg14 PF10186.4 EIE89113.1 - 0.079 11.8 7.9 0.17 10.8 5.5 1.5 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 FlaC_arch PF05377.6 EIE89113.1 - 7.1 6.6 9.4 12 5.8 0.3 4.1 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) ZapA PF05164.8 EIE89113.1 - 9.9 6.2 9.4 0.72 9.8 0.3 3.4 3 0 0 3 3 3 0 Cell division protein ZapA MFS_1 PF07690.11 EIE89114.1 - 1.9e-34 118.9 40.7 2.7e-24 85.5 14.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIE89114.1 - 8e-13 47.7 32.3 5.3e-12 45.0 10.9 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter DUF912 PF06024.7 EIE89114.1 - 0.59 10.2 5.3 18 5.4 0.2 3.8 3 1 1 4 4 4 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Nucleopor_Nup85 PF07575.8 EIE89115.1 - 1.1e-09 37.1 0.9 3.6e-06 25.4 0.6 2.8 1 1 0 1 1 1 1 Nup85 Nucleoporin M16C_assoc PF08367.6 EIE89115.1 - 0.079 11.8 0.2 0.11 11.3 0.1 1.2 1 0 0 1 1 1 0 Peptidase M16C associated MHYT PF03707.11 EIE89116.1 - 2.5e-09 37.1 6.0 5.6e-05 23.1 1.4 2.6 2 0 0 2 2 2 2 Bacterial signalling protein N terminal repeat Translin PF01997.11 EIE89117.1 - 9.5e-32 110.2 0.3 6.7e-20 71.5 0.0 2.1 2 0 0 2 2 2 2 Translin family BLOC1_2 PF10046.4 EIE89117.1 - 0.0055 16.8 1.5 2.8 8.1 0.2 2.4 2 1 0 2 2 2 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.7 EIE89117.1 - 0.02 15.1 0.2 5.4 7.3 0.0 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF1479 PF07350.7 EIE89117.1 - 0.029 12.8 0.1 0.045 12.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) Syntaxin PF00804.20 EIE89117.1 - 0.043 13.9 1.9 0.6 10.3 0.1 2.4 2 0 0 2 2 2 0 Syntaxin IncA PF04156.9 EIE89117.1 - 0.046 13.3 2.7 0.57 9.7 0.3 2.1 2 0 0 2 2 2 0 IncA protein TBPIP PF07106.8 EIE89117.1 - 0.05 13.1 2.3 0.35 10.3 0.1 2.1 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) GMP_synt_C PF00958.17 EIE89117.1 - 0.074 12.7 0.0 0.2 11.4 0.0 1.7 1 0 0 1 1 1 0 GMP synthase C terminal domain GerA PF03323.8 EIE89117.1 - 0.14 10.2 0.0 0.18 9.9 0.0 1.1 1 0 0 1 1 1 0 Bacillus/Clostridium GerA spore germination protein DUF1664 PF07889.7 EIE89117.1 - 0.16 11.8 0.5 7 6.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Metallophos PF00149.23 EIE89118.1 - 7.9e-18 64.5 2.9 1.2e-17 64.0 2.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase 3Beta_HSD PF01073.14 EIE89119.1 - 7.3e-68 228.2 0.0 9e-68 227.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EIE89119.1 - 8e-32 110.5 0.0 9.9e-32 110.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIE89119.1 - 1.7e-15 57.5 0.0 2.3e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 EIE89119.1 - 2.9e-14 52.6 0.0 3.8e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 EIE89119.1 - 2e-13 49.8 0.0 1.2e-11 44.0 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.10 EIE89119.1 - 2e-06 26.9 0.0 1.3e-05 24.2 0.0 2.3 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.5 EIE89119.1 - 0.00087 18.9 0.0 0.044 13.4 0.0 2.3 1 1 0 1 1 1 1 KR domain adh_short PF00106.20 EIE89119.1 - 0.0068 16.3 0.0 0.095 12.6 0.0 2.3 1 1 0 1 1 1 1 short chain dehydrogenase RNA_pol_A_bac PF01000.21 EIE89120.1 - 4.3e-34 117.0 0.1 6e-34 116.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EIE89120.1 - 2e-09 36.4 0.0 2.7e-09 35.9 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF22 PF01629.11 EIE89120.1 - 0.039 13.4 0.1 0.087 12.3 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function DUF22 NPDC1 PF06809.6 EIE89121.1 - 0.17 10.6 2.0 0.1 11.3 0.4 1.4 1 1 0 1 1 1 0 Neural proliferation differentiation control-1 protein (NPDC1) MPP6 PF10175.4 EIE89122.1 - 0.0031 17.8 1.2 0.0032 17.8 0.8 1.0 1 0 0 1 1 1 1 M-phase phosphoprotein 6 GBP_C PF02841.9 EIE89122.1 - 0.29 10.2 1.8 0.32 10.1 1.3 1.0 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain zf-C2H2 PF00096.21 EIE89123.1 - 3e-09 36.6 18.3 9e-05 22.5 1.8 3.8 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIE89123.1 - 9.1e-09 35.1 18.7 3.6e-07 30.1 0.4 4.0 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EIE89123.1 - 1.3e-06 28.3 11.7 0.0059 16.8 0.2 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EIE89123.1 - 0.0026 17.8 5.8 0.01 15.9 1.0 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 EIE89123.1 - 0.0086 15.8 2.4 0.6 9.9 0.1 2.6 2 0 0 2 2 2 1 BED zinc finger zf-met PF12874.2 EIE89123.1 - 0.031 14.4 6.0 0.51 10.6 1.0 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EIE89123.1 - 0.24 11.3 4.2 2.6 8.0 0.6 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-U1 PF06220.7 EIE89123.1 - 1.4 8.4 6.4 0.31 10.6 1.8 1.9 2 0 0 2 2 2 0 U1 zinc finger zf-H2C2_5 PF13909.1 EIE89123.1 - 7.5 7.0 10.1 16 5.9 0.1 3.7 3 0 0 3 3 3 0 C2H2-type zinc-finger domain Ricin_B_lectin PF00652.17 EIE89124.1 - 5e-55 184.8 21.7 3.5e-08 33.5 0.0 15.2 10 3 5 15 15 15 14 Ricin-type beta-trefoil lectin domain UCR_TM PF02921.9 EIE89125.1 - 9.2e-20 70.6 2.7 2e-19 69.5 1.9 1.5 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.21 EIE89125.1 - 4e-18 64.7 0.1 7e-18 63.9 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain CesA PF11439.3 EIE89127.1 - 0.046 13.6 0.2 0.062 13.2 0.2 1.2 1 0 0 1 1 1 0 Type III secretion system filament chaperone CesA Hydrophobin_2 PF06766.6 EIE89127.1 - 0.14 11.8 1.6 0.27 10.9 1.1 1.4 1 0 0 1 1 1 0 Fungal hydrophobin DDE_3 PF13358.1 EIE89128.1 - 1.3e-22 80.1 0.0 1.6e-22 79.7 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE89128.1 - 0.014 15.4 0.0 0.028 14.5 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain DUF4240 PF14024.1 EIE89128.1 - 0.097 12.5 0.0 0.22 11.3 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4240) Asp PF00026.18 EIE89129.1 - 1.6e-52 178.7 0.0 2e-52 178.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIE89129.1 - 0.00011 22.2 0.0 0.0016 18.3 0.0 2.6 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EIE89129.1 - 0.00092 18.7 0.1 0.004 16.7 0.0 1.9 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 EIE89129.1 - 0.017 15.5 0.1 15 6.1 0.0 3.2 2 1 0 2 2 2 0 Aspartyl protease Peptidase_S10 PF00450.17 EIE89130.1 - 2.2e-113 379.5 5.3 2.7e-113 379.2 3.7 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase OPT PF03169.10 EIE89131.1 - 1.6e-96 324.1 38.8 1.8e-96 323.9 26.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein VIT1 PF01988.14 EIE89131.1 - 7.2e-06 25.6 0.2 1.1 8.7 1.2 4.2 4 2 0 4 4 4 2 VIT family COX14 PF14880.1 EIE89131.1 - 8 6.1 5.9 38 3.9 0.5 3.0 2 0 0 2 2 2 0 Cytochrome oxidase c assembly TFIIF_beta PF02270.10 EIE89132.1 - 1.1e-67 228.7 0.8 1.8e-42 146.0 0.0 2.1 1 1 1 2 2 2 2 Transcription initiation factor IIF, beta subunit POX PF07526.6 EIE89132.1 - 0.13 12.5 1.1 0.3 11.3 0.8 1.5 1 0 0 1 1 1 0 Associated with HOX Actin PF00022.14 EIE89133.1 - 7.1e-131 436.2 0.0 8e-131 436.0 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EIE89133.1 - 9.5e-09 34.2 0.0 3.2e-05 22.6 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein DDE_3 PF13358.1 EIE89137.1 - 1.8e-21 76.4 0.1 3.6e-21 75.4 0.1 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE89137.1 - 1.6e-15 56.8 1.3 5.3e-15 55.2 0.3 2.3 3 0 0 3 3 3 1 Transposase HTH_29 PF13551.1 EIE89137.1 - 4.5e-06 26.7 0.1 1.8e-05 24.8 0.1 2.0 2 0 0 2 2 2 1 Winged helix-turn helix HTH_38 PF13936.1 EIE89137.1 - 4.6e-05 22.8 0.0 0.00014 21.3 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_32 PF13565.1 EIE89137.1 - 0.00012 22.7 3.3 0.0093 16.7 0.1 3.7 3 1 1 4 4 3 1 Homeodomain-like domain Sigma70_r4_2 PF08281.7 EIE89137.1 - 0.00016 21.0 0.6 0.0052 16.2 0.0 3.1 4 0 0 4 4 4 1 Sigma-70, region 4 HTH_23 PF13384.1 EIE89137.1 - 0.00017 21.1 0.0 0.0061 16.1 0.0 2.7 2 0 0 2 2 2 1 Homeodomain-like domain rve PF00665.21 EIE89137.1 - 0.00072 19.6 0.0 0.0022 18.1 0.0 2.0 2 1 0 2 2 2 1 Integrase core domain HTH_21 PF13276.1 EIE89137.1 - 0.0021 18.0 0.2 0.13 12.2 0.0 2.8 3 0 0 3 3 2 1 HTH-like domain Sigma70_r4 PF04545.11 EIE89137.1 - 0.0054 16.0 0.1 0.045 13.0 0.0 2.6 4 0 0 4 4 4 1 Sigma-70, region 4 HTH_7 PF02796.10 EIE89137.1 - 0.0059 16.4 1.3 0.24 11.2 0.0 2.8 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase HTH_28 PF13518.1 EIE89137.1 - 0.008 16.1 0.0 0.035 14.1 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain LacI PF00356.16 EIE89137.1 - 0.015 14.9 1.3 2.8 7.6 0.2 2.6 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family HTH_36 PF13730.1 EIE89137.1 - 0.054 13.6 0.3 3.4 7.8 0.0 3.0 3 0 0 3 3 2 0 Helix-turn-helix domain GcrA PF07750.6 EIE89137.1 - 0.059 13.5 0.1 0.098 12.8 0.1 1.3 1 0 0 1 1 1 0 GcrA cell cycle regulator CPSase_L_D3 PF02787.14 EIE89137.1 - 0.075 12.8 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain UPF0122 PF04297.9 EIE89137.1 - 0.081 12.9 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like HTH_Tnp_4 PF13613.1 EIE89137.1 - 0.11 12.0 0.1 0.28 10.7 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_17 PF12728.2 EIE89137.1 - 0.19 11.9 2.7 15 5.9 0.1 3.3 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.1 EIE89137.1 - 0.46 9.7 4.1 8.7 5.6 0.0 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 rve PF00665.21 EIE89138.1 - 3e-23 82.2 0.0 7.5e-23 80.9 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE89138.1 - 9e-16 57.8 0.3 2.1e-15 56.6 0.2 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE89138.1 - 4e-11 42.3 1.1 9.6e-11 41.1 0.7 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.12 EIE89138.1 - 0.00053 20.0 0.9 0.0024 17.9 0.6 2.2 1 0 0 1 1 1 1 Retrotransposon gag protein zf-H2C2 PF09337.5 EIE89138.1 - 0.0014 18.0 0.1 0.0041 16.4 0.1 1.9 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Asp_protease_2 PF13650.1 EIE89138.1 - 0.0054 17.1 0.2 0.014 15.9 0.2 1.8 1 0 0 1 1 1 1 Aspartyl protease rve_3 PF13683.1 EIE89138.1 - 0.0076 15.7 0.1 0.05 13.1 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain UBN2_2 PF14227.1 EIE89138.1 - 0.024 14.1 5.6 0.049 13.1 0.0 3.3 3 0 0 3 3 3 0 gag-polypeptide of LTR copia-type Asp_protease PF09668.5 EIE89138.1 - 0.04 13.4 0.1 0.12 11.9 0.1 1.8 1 1 0 1 1 1 0 Aspartyl protease UBN2 PF14223.1 EIE89138.1 - 0.059 13.1 0.1 0.22 11.3 0.1 2.0 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type HTH_Tnp_Tc3_2 PF01498.13 EIE89140.1 - 8e-06 25.8 0.3 1e-05 25.5 0.2 1.1 1 0 0 1 1 1 1 Transposase DDE_Tnp_ISAZ013 PF07592.6 EIE89140.1 - 0.091 11.4 0.2 0.091 11.4 0.1 1.0 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain Galactosyl_T PF01762.16 EIE89140.1 - 0.1 12.1 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Galactosyltransferase TRAPP PF04051.11 EIE89140.1 - 0.11 12.0 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 Transport protein particle (TRAPP) component DDE_3 PF13358.1 EIE89141.1 - 4.6e-13 49.1 0.1 7.2e-13 48.5 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE89141.1 - 3e-10 40.0 0.3 4.7e-10 39.3 0.2 1.3 1 0 0 1 1 1 1 Transposase rve PF00665.21 EIE89142.1 - 4.6e-18 65.4 0.0 1.1e-17 64.2 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE89142.1 - 5.4e-15 55.3 0.3 1.3e-14 54.0 0.2 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 EIE89142.1 - 0.0032 17.9 0.0 0.0083 16.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EIE89142.1 - 0.042 13.6 0.0 0.086 12.6 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF2759 PF10958.3 EIE89142.1 - 0.24 11.0 0.8 0.51 9.9 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2759) rve PF00665.21 EIE89144.1 - 1.1e-16 60.9 0.0 4.8e-16 58.9 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE89144.1 - 6.1e-11 42.0 0.5 4.9e-10 39.1 0.2 2.6 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE89144.1 - 2.8e-08 33.3 2.9 9.9e-08 31.5 0.1 2.9 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain RVP PF00077.15 EIE89144.1 - 0.002 17.9 0.1 0.0088 15.9 0.1 2.2 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 EIE89144.1 - 0.0042 17.5 0.1 0.0092 16.4 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.12 EIE89144.1 - 0.033 14.2 0.0 0.26 11.4 0.0 2.6 1 0 0 1 1 1 0 Retrotransposon gag protein SSDP PF04503.8 EIE89145.1 - 1.3 8.7 6.0 1.6 8.3 4.2 1.1 1 0 0 1 1 1 0 Single-stranded DNA binding protein, SSDP DDE_3 PF13358.1 EIE89146.1 - 3.3e-12 46.3 0.0 4.1e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF2567 PF10821.3 EIE89146.1 - 0.045 13.2 0.0 0.06 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2567) HCBP_related PF06594.6 EIE89146.1 - 0.089 12.4 0.1 1.7 8.3 0.0 2.7 3 0 0 3 3 3 0 Haemolysin-type calcium binding protein related domain DDE_3 PF13358.1 EIE89147.1 - 3.5e-22 78.7 0.2 5.2e-22 78.1 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE89147.1 - 0.001 19.1 0.0 0.0032 17.5 0.0 2.0 1 1 0 1 1 1 1 Integrase core domain THP2 PF09432.5 EIE89147.1 - 0.014 15.2 0.1 0.63 9.9 0.0 2.3 2 0 0 2 2 2 0 Tho complex subunit THP2 rve PF00665.21 EIE89148.1 - 1.7e-22 79.7 0.0 4.3e-22 78.4 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE89148.1 - 4.5e-16 58.8 0.1 9.1e-16 57.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.12 EIE89148.1 - 8.5e-09 35.3 0.1 2.4e-08 33.9 0.0 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein Chromo PF00385.19 EIE89148.1 - 4e-08 32.8 0.1 9.2e-08 31.6 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.1 EIE89148.1 - 4.9e-05 23.7 0.0 0.00011 22.5 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.5 EIE89148.1 - 0.00039 19.7 1.5 0.0014 18.0 1.1 2.1 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Asp_protease PF09668.5 EIE89148.1 - 0.0079 15.7 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EIE89148.1 - 0.021 14.6 0.0 0.053 13.3 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease HTH_Tnp_Tc3_2 PF01498.13 EIE89149.1 - 1.6e-08 34.5 0.4 1.6e-08 34.5 0.3 2.1 1 1 1 2 2 2 1 Transposase HTH_29 PF13551.1 EIE89149.1 - 0.00051 20.1 1.7 0.0013 18.8 1.2 1.7 1 1 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_ISL3 PF13542.1 EIE89149.1 - 0.0066 15.5 1.8 0.021 13.9 0.5 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_12 PF08461.5 EIE89149.1 - 0.067 12.9 0.1 0.19 11.4 0.0 1.7 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain HTH_21 PF13276.1 EIE89149.1 - 0.078 12.9 1.7 0.66 10.0 0.0 2.3 2 0 0 2 2 2 0 HTH-like domain HTH_32 PF13565.1 EIE89149.1 - 0.12 13.1 2.6 0.13 13.0 0.7 1.9 2 0 0 2 2 2 0 Homeodomain-like domain HTH_23 PF13384.1 EIE89149.1 - 0.14 11.8 2.9 1.9 8.2 0.2 2.5 2 0 0 2 2 2 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.13 EIE89151.1 - 1.6e-07 31.2 1.5 1.9e-07 31.0 0.2 1.9 2 1 0 2 2 2 1 Transposase DDE_3 PF13358.1 EIE89152.1 - 1.6e-20 73.3 0.0 2.6e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_IS1595 PF12762.2 EIE89153.1 - 2.9e-06 27.2 0.1 5.3e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 ISXO2-like transposase domain Exo_endo_phos_2 PF14529.1 EIE89154.1 - 3.9e-15 55.4 0.0 1.1e-14 54.0 0.0 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EIE89154.1 - 5.8e-06 26.4 0.1 1.5e-05 25.0 0.1 1.7 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF972 PF06156.8 EIE89154.1 - 0.00013 22.2 1.7 0.00023 21.4 1.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF972) TSC22 PF01166.13 EIE89154.1 - 0.00016 21.5 0.6 0.00036 20.4 0.4 1.5 1 0 0 1 1 1 1 TSC-22/dip/bun family DUF904 PF06005.7 EIE89154.1 - 0.037 14.3 2.3 0.092 13.0 1.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF904) Transposase_21 PF02992.9 EIE89155.1 - 2.2e-20 72.7 1.4 4.1e-20 71.8 0.0 1.9 2 0 0 2 2 2 1 Transposase family tnp2 rve PF00665.21 EIE89156.1 - 3.3e-15 56.2 0.0 7.3e-15 55.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE89156.1 - 5.1e-15 55.4 0.1 1.1e-14 54.2 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE89156.1 - 4.8e-09 35.7 0.5 1.1e-08 34.5 0.3 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.1 EIE89156.1 - 1.8e-07 31.5 0.0 4.7e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 EIE89156.1 - 5.3e-07 29.4 0.1 3.3e-06 26.9 0.0 2.4 2 0 0 2 2 2 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EIE89156.1 - 0.00085 19.0 0.0 0.002 17.9 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.12 EIE89156.1 - 0.0038 17.2 0.1 0.0038 17.2 0.0 3.2 4 0 0 4 4 4 1 Retrotransposon gag protein Asp_protease PF09668.5 EIE89156.1 - 0.0042 16.6 0.2 0.027 14.0 0.1 2.2 2 0 0 2 2 2 1 Aspartyl protease Tudor-knot PF11717.3 EIE89156.1 - 0.022 14.4 0.2 0.086 12.5 0.1 2.0 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain DDE_3 PF13358.1 EIE89157.1 - 7.3e-12 45.2 1.7 3.7e-10 39.7 1.0 2.3 1 1 1 2 2 2 2 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE89157.1 - 2.8e-07 30.4 0.4 7.3e-07 29.1 0.1 2.0 2 0 0 2 2 2 1 Transposase NUDIX_4 PF14815.1 EIE89157.1 - 0.043 13.2 0.3 0.074 12.4 0.2 1.4 1 0 0 1 1 1 0 NUDIX domain HTH_Tnp_ISL3 PF13542.1 EIE89158.1 - 9e-05 21.5 0.2 0.00011 21.2 0.1 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_28 PF13518.1 EIE89158.1 - 0.0033 17.3 0.0 0.0046 16.9 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.1 EIE89158.1 - 0.0059 16.2 0.0 0.0065 16.0 0.0 1.2 1 0 0 1 1 1 1 Homeodomain-like domain HTH_11 PF08279.7 EIE89158.1 - 0.0084 15.7 0.0 0.0098 15.5 0.0 1.2 1 0 0 1 1 1 1 HTH domain MerR PF00376.18 EIE89158.1 - 0.068 12.7 0.1 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 MerR family regulatory protein Sigma70_r4_2 PF08281.7 EIE89158.1 - 0.13 11.7 0.1 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_7 PF02796.10 EIE89158.1 - 0.13 12.1 0.0 0.15 11.9 0.0 1.1 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase ETC_C1_NDUFA4 PF04800.7 EIE89159.1 - 3.9e-35 119.7 1.6 5e-35 119.3 1.1 1.1 1 0 0 1 1 1 1 ETC complex I subunit conserved region Alpha-amylase_C PF02806.13 EIE89160.1 - 7.6e-26 90.0 0.1 2.4e-25 88.4 0.1 1.9 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 EIE89160.1 - 1.2e-16 61.0 0.0 3e-11 43.2 0.0 2.4 1 1 1 2 2 2 2 Alpha amylase, catalytic domain CBM_48 PF02922.13 EIE89160.1 - 3.1e-14 52.7 0.1 8.3e-14 51.4 0.1 1.7 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Fork_head PF00250.13 EIE89161.1 - 2.2e-30 104.5 0.1 4.6e-30 103.5 0.1 1.5 1 0 0 1 1 1 1 Fork head domain Corona_NS1 PF06145.6 EIE89162.1 - 1 8.7 3.5 1.8 7.9 2.5 1.5 1 1 0 1 1 1 0 Coronavirus nonstructural protein NS1 GAT PF03127.9 EIE89163.1 - 5e-08 32.8 0.5 1.4e-07 31.4 0.3 1.6 1 1 0 1 1 1 1 GAT domain Mito_fiss_reg PF05308.6 EIE89163.1 - 0.46 9.8 12.9 0.1 11.9 0.5 2.2 2 0 0 2 2 2 0 Mitochondrial fission regulator Glyco_hydro_16 PF00722.16 EIE89164.1 - 9.3e-35 119.5 1.3 1.3e-34 119.1 0.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 BiPBP_C PF06832.7 EIE89164.1 - 0.044 13.6 0.1 0.082 12.8 0.1 1.5 1 0 0 1 1 1 0 Penicillin-Binding Protein C-terminus Family Aa_trans PF01490.13 EIE89166.1 - 1.6e-58 198.1 30.6 1.8e-58 197.9 21.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.1 EIE89166.1 - 4.9e-07 28.6 41.6 1.2e-06 27.4 28.8 1.5 1 1 0 1 1 1 1 Amino acid permease MIG-14_Wnt-bd PF06664.7 EIE89166.1 - 8.2 5.1 13.3 0.42 9.3 3.6 2.7 1 1 2 3 3 3 0 Wnt-binding factor required for Wnt secretion Sulfotransfer_3 PF13469.1 EIE89167.1 - 0.00018 22.4 0.0 0.00025 22.0 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase family Porin_3 PF01459.17 EIE89168.1 - 4e-65 219.8 6.0 4.5e-65 219.6 4.2 1.0 1 0 0 1 1 1 1 Eukaryotic porin Caps_assemb_Wzi PF14052.1 EIE89168.1 - 0.008 15.0 1.2 0.038 12.8 0.2 2.0 2 0 0 2 2 2 1 Capsule assembly protein Wzi SDA1 PF05285.7 EIE89169.1 - 4.1e-80 269.4 53.7 1.5e-79 267.6 28.8 2.2 2 0 0 2 2 2 2 SDA1 NUC130_3NT PF08158.7 EIE89169.1 - 8e-22 77.2 0.2 2.1e-21 75.9 0.1 1.8 1 0 0 1 1 1 1 NUC130/3NT domain Mating_N PF12731.2 EIE89169.1 - 0.012 15.4 0.1 0.04 13.7 0.1 1.9 1 0 0 1 1 1 0 Mating-type protein beta 1 Imm45 PF15603.1 EIE89169.1 - 0.052 13.6 3.7 0.06 13.5 0.5 2.5 2 0 0 2 2 2 0 Immunity protein 45 TGT PF01702.13 EIE89170.1 - 4.3e-76 255.3 0.2 4.9e-72 242.0 0.0 2.1 1 1 1 2 2 2 2 Queuine tRNA-ribosyltransferase DDE_3 PF13358.1 EIE89171.1 - 8.6e-32 109.8 0.0 1.7e-31 108.9 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.1 EIE89171.1 - 0.00014 22.6 0.0 0.0026 18.5 0.0 2.6 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_1 PF01527.15 EIE89171.1 - 0.00017 21.4 0.2 0.00039 20.3 0.1 1.6 1 0 0 1 1 1 1 Transposase DDE_Tnp_ISAZ013 PF07592.6 EIE89171.1 - 0.0013 17.5 0.1 1.3 7.7 0.0 2.5 2 1 1 3 3 3 2 Rhodopirellula transposase DDE domain CP12 PF02672.10 EIE89171.1 - 0.006 17.0 0.8 0.016 15.6 0.5 1.7 1 0 0 1 1 1 1 CP12 domain HTH_28 PF13518.1 EIE89171.1 - 0.011 15.6 0.0 0.047 13.7 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_psq PF05225.11 EIE89171.1 - 0.012 15.1 0.2 0.085 12.4 0.1 2.2 2 0 0 2 2 2 0 helix-turn-helix, Psq domain YniB PF14002.1 EIE89171.1 - 0.027 13.9 0.0 0.48 9.8 0.0 2.1 2 0 0 2 2 2 0 YniB-like protein HTH_29 PF13551.1 EIE89171.1 - 0.043 13.9 0.0 0.15 12.1 0.0 1.9 2 0 0 2 2 2 0 Winged helix-turn helix FAM219A PF15260.1 EIE89171.1 - 0.078 13.3 0.2 0.14 12.5 0.1 1.3 1 0 0 1 1 1 0 Protein family FAM219A Pox_A_type_inc PF04508.7 EIE89172.1 - 0.03 14.0 0.2 0.03 14.0 0.1 21.0 23 1 1 24 24 24 0 Viral A-type inclusion protein repeat Reo_sigmaC PF04582.7 EIE89172.1 - 5.9 5.9 118.5 0.016 14.3 5.9 11.0 2 2 7 11 11 11 0 Reovirus sigma C capsid protein Med9 PF07544.8 EIE89173.1 - 0.0058 16.3 22.7 0.29 10.9 6.3 3.3 2 1 0 2 2 2 2 RNA polymerase II transcription mediator complex subunit 9 TMEM247 PF15444.1 EIE89173.1 - 1.5 8.6 16.6 0.08 12.7 5.9 2.2 1 1 1 2 2 2 0 Transmembrane protein 247 Fib_alpha PF08702.5 EIE89173.1 - 3.5 7.7 21.0 3.2 7.8 5.9 2.7 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family SEP PF08059.8 EIE89174.1 - 1.1e-27 96.1 0.2 3.7e-27 94.4 0.0 1.9 2 0 0 2 2 2 1 SEP domain UBA_4 PF14555.1 EIE89174.1 - 2.9e-16 58.7 1.3 5.1e-16 57.9 0.9 1.4 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 EIE89174.1 - 2.4e-07 30.7 0.0 5.4e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 UBX domain zf-C2H2_4 PF13894.1 EIE89175.1 - 9.4e-10 38.1 9.0 9.3e-05 22.4 1.3 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EIE89175.1 - 2.2e-07 30.7 10.4 0.00032 20.8 1.2 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIE89175.1 - 7.3e-06 26.0 9.9 0.00027 21.0 0.9 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-Di19 PF05605.7 EIE89175.1 - 2.9e-05 24.0 3.4 4.6e-05 23.4 2.3 1.3 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.1 EIE89175.1 - 0.0066 16.6 0.6 0.0066 16.6 0.4 2.8 2 1 0 2 2 2 1 C2H2-type zinc-finger domain Terminase_GpA PF05876.7 EIE89175.1 - 0.057 11.7 0.6 0.074 11.3 0.4 1.1 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) DUF1465 PF07323.7 EIE89175.1 - 0.094 12.2 1.0 0.13 11.8 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1465) OrfB_Zn_ribbon PF07282.6 EIE89175.1 - 0.15 11.7 4.8 0.59 9.8 3.3 2.0 1 1 0 1 1 1 0 Putative transposase DNA-binding domain DUF454 PF04304.8 EIE89175.1 - 0.18 11.8 0.0 0.28 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF454) zf-C2H2_jaz PF12171.3 EIE89175.1 - 0.37 10.9 3.8 7.6 6.8 0.3 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Elf1 PF05129.8 EIE89175.1 - 0.39 10.4 6.8 1.4 8.6 4.7 1.8 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like Radical_SAM PF04055.16 EIE89177.1 - 1.9e-16 60.6 0.0 5.1e-16 59.2 0.0 1.7 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 EIE89177.1 - 2.2e-11 43.5 0.0 6e-11 42.2 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Reo_sigmaC PF04582.7 EIE89178.1 - 0.0036 16.5 6.6 0.0043 16.2 4.6 1.2 1 0 0 1 1 1 1 Reovirus sigma C capsid protein DUF1227 PF06777.6 EIE89178.1 - 0.012 15.2 2.0 0.024 14.3 1.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1227) ParB PF08775.5 EIE89178.1 - 0.033 14.4 3.7 0.057 13.7 2.5 1.3 1 0 0 1 1 1 0 ParB family SecD-TM1 PF13721.1 EIE89178.1 - 0.057 13.6 3.7 0.069 13.4 2.3 1.4 1 1 0 1 1 1 0 SecD export protein N-terminal TM region Mga PF05043.8 EIE89178.1 - 0.11 12.8 7.5 0.18 12.0 2.7 2.1 1 1 1 2 2 2 0 Mga helix-turn-helix domain DUF651 PF04895.7 EIE89178.1 - 0.11 12.0 3.9 0.055 13.0 0.6 1.9 2 0 0 2 2 2 0 Archaeal protein of unknown function (DUF651) DUF3718 PF12514.3 EIE89178.1 - 0.14 12.2 1.9 0.27 11.3 1.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3718) ArsR PF09824.4 EIE89178.1 - 0.19 11.0 2.9 0.74 9.1 0.4 2.1 1 1 2 3 3 3 0 ArsR transcriptional regulator Tweety PF04906.8 EIE89178.1 - 0.64 8.3 8.7 1.1 7.5 6.0 1.4 1 1 0 1 1 1 0 Tweety Spectrin PF00435.16 EIE89178.1 - 0.8 10.0 9.1 19 5.6 6.3 2.2 1 1 0 1 1 1 0 Spectrin repeat DUF1664 PF07889.7 EIE89178.1 - 1.8 8.3 7.8 1.6 8.5 2.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF745 PF05335.8 EIE89178.1 - 1.9 7.9 9.5 2.3 7.6 6.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF745) Spc7 PF08317.6 EIE89178.1 - 2 6.9 12.8 1.7 7.1 1.4 1.8 1 1 0 1 1 1 0 Spc7 kinetochore protein LRS4 PF10422.4 EIE89178.1 - 2.1 7.6 12.5 2.5 7.4 8.7 1.1 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 Laminin_II PF06009.7 EIE89178.1 - 2.4 7.9 13.6 1.1 8.9 6.1 2.0 1 1 1 2 2 2 0 Laminin Domain II Atg14 PF10186.4 EIE89178.1 - 3.6 6.4 12.7 4.5 6.1 8.8 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 NPV_P10 PF05531.7 EIE89178.1 - 4.7 7.5 12.1 5 7.4 2.4 2.7 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein Toxin_52 PF15605.1 EIE89178.1 - 6.9 6.6 9.3 0.95 9.3 1.3 2.4 1 1 1 2 2 2 0 Putative toxin 52 GLE1 PF07817.8 EIE89178.1 - 9 5.1 10.2 4 6.3 3.6 1.8 1 1 1 2 2 2 0 GLE1-like protein WXG100 PF06013.7 EIE89178.1 - 9.1 6.3 10.7 7.1 6.7 2.2 3.3 1 1 2 3 3 3 0 Proteins of 100 residues with WXG Kinesin PF00225.18 EIE89179.1 - 1.6e-97 326.2 6.5 6.9e-97 324.1 0.1 3.5 3 1 0 3 3 3 2 Kinesin motor domain DUF3694 PF12473.3 EIE89179.1 - 1.8e-25 89.2 0.9 4.9e-25 87.8 0.6 1.8 1 0 0 1 1 1 1 Kinesin protein Metallophos PF00149.23 EIE89180.1 - 4.3e-34 117.6 0.0 5.5e-34 117.3 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ACT_7 PF13840.1 EIE89181.1 - 6.5e-23 80.0 0.0 1e-22 79.3 0.0 1.3 1 0 0 1 1 1 1 ACT domain DUF2007 PF09413.5 EIE89181.1 - 0.0031 17.2 0.0 0.0063 16.3 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF2007) Lipocalin_7 PF14651.1 EIE89181.1 - 0.012 15.3 0.0 0.032 13.9 0.0 1.6 1 1 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family ACT PF01842.20 EIE89181.1 - 0.082 12.4 0.0 0.17 11.4 0.0 1.5 1 1 0 1 1 1 0 ACT domain DUF1212 PF06738.7 EIE89182.1 - 3.1e-33 114.8 10.3 1.8e-27 96.0 0.2 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 EIE89182.1 - 3.1e-18 65.9 10.3 3.1e-18 65.9 7.2 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3815) E1-E2_ATPase PF00122.15 EIE89187.1 - 1e-57 194.8 7.9 1e-57 194.8 5.5 2.4 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EIE89187.1 - 5.1e-28 98.9 0.2 1.1e-27 97.9 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EIE89187.1 - 2.1e-16 60.6 0.1 6.3e-16 59.1 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EIE89187.1 - 1.3e-08 34.1 0.0 4e-08 32.5 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EIE89187.1 - 0.0015 18.1 0.1 0.0052 16.4 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase cNMP_binding PF00027.24 EIE89188.1 - 2.1e-40 136.4 0.0 5.3e-21 74.2 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain F-box PF00646.28 EIE89188.1 - 7.5e-06 25.4 1.6 2.9e-05 23.5 0.6 2.4 1 1 1 2 2 2 1 F-box domain F-box-like PF12937.2 EIE89188.1 - 0.06 13.0 0.1 0.19 11.4 0.1 1.9 1 0 0 1 1 1 0 F-box-like Cupin_3 PF05899.7 EIE89188.1 - 0.12 11.7 0.0 0.36 10.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Mcp5_PH PF12814.2 EIE89189.1 - 1.6e-31 108.7 0.5 1.6e-31 108.7 0.3 2.6 2 0 0 2 2 2 1 Meiotic cell cortex C-terminal pleckstrin homology ATP-synt_Eps PF04627.8 EIE89189.1 - 0.31 10.6 8.5 0.023 14.2 0.5 3.1 2 0 0 2 2 2 0 Mitochondrial ATP synthase epsilon chain FATC PF02260.15 EIE89189.1 - 0.73 9.3 4.3 85 2.7 0.0 5.0 5 0 0 5 5 5 0 FATC domain DUF2370 PF10176.4 EIE89190.1 - 5.7e-47 160.0 4.8 1e-33 116.6 2.1 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF2370) RVT_1 PF00078.22 EIE89191.1 - 2.2e-30 105.6 0.1 3.5e-30 104.9 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HTH_Tnp_Tc3_2 PF01498.13 EIE89192.1 - 1.6e-16 60.0 1.1 3.5e-16 58.9 0.8 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.1 EIE89192.1 - 2.9e-16 59.5 0.0 5e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 EIE89192.1 - 2.3e-08 34.1 0.4 3.6e-07 30.3 0.0 2.7 3 0 0 3 3 3 1 Winged helix-turn helix HTH_23 PF13384.1 EIE89192.1 - 0.00016 21.2 0.1 0.00061 19.3 0.0 2.0 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.1 EIE89192.1 - 0.0018 18.2 0.0 0.0062 16.5 0.0 2.0 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_17 PF12728.2 EIE89192.1 - 0.0074 16.5 0.6 0.29 11.3 0.0 3.0 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_24 PF13412.1 EIE89192.1 - 0.011 15.1 0.0 0.14 11.5 0.0 2.5 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding HTH_38 PF13936.1 EIE89192.1 - 0.012 15.1 0.0 0.036 13.6 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_7 PF02796.10 EIE89192.1 - 0.046 13.5 0.4 1 9.2 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase SpoIIID PF12116.3 EIE89192.1 - 0.046 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Stage III sporulation protein D HTH_IclR PF09339.5 EIE89192.1 - 0.049 13.2 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain MerR PF00376.18 EIE89192.1 - 0.07 12.6 0.3 7.2 6.2 0.0 3.0 3 0 0 3 3 3 0 MerR family regulatory protein zf-RVT PF13966.1 EIE89197.1 - 3.1e-06 27.3 0.8 3.1e-06 27.3 0.6 2.1 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase RVT_1 PF00078.22 EIE89198.1 - 1.6e-07 30.9 0.0 2.5e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Cbl_N3 PF02762.9 EIE89198.1 - 0.044 13.4 0.0 12 5.6 0.1 2.8 3 0 0 3 3 3 0 CBL proto-oncogene N-terminus, SH2-like domain DUF2509 PF10713.4 EIE89198.1 - 0.067 12.9 0.3 0.11 12.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2509) Y_phosphatase2 PF03162.8 EIE89201.1 - 2.2e-33 114.9 0.0 2.7e-33 114.6 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 EIE89201.1 - 3.4e-09 37.1 0.0 4.3e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 EIE89201.1 - 2.4e-05 23.8 0.0 2.7e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 EIE89201.1 - 0.00028 20.4 0.0 0.00031 20.3 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Myotub-related PF06602.9 EIE89201.1 - 0.017 13.9 0.0 0.02 13.6 0.0 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain OmpH PF03938.9 EIE89202.1 - 0.0086 16.0 2.2 0.0096 15.8 1.5 1.2 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) TFR_dimer PF04253.10 EIE89202.1 - 0.024 14.2 0.4 0.032 13.8 0.3 1.3 1 0 0 1 1 1 0 Transferrin receptor-like dimerisation domain DUF3355 PF11835.3 EIE89202.1 - 0.08 12.7 0.0 0.088 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3355) Tox-REase-3 PF15647.1 EIE89202.1 - 0.11 12.3 2.6 0.12 12.2 1.8 1.1 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 3 DUF499 PF04465.7 EIE89202.1 - 0.14 9.6 0.9 0.13 9.7 0.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF499) DivIC PF04977.10 EIE89202.1 - 2.5 7.6 5.3 1.8 8.1 2.6 1.5 1 1 1 2 2 2 0 Septum formation initiator DDE_Tnp_IS1595 PF12762.2 EIE89203.1 - 1.8e-18 66.8 0.0 2.9e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 ISXO2-like transposase domain rve PF00665.21 EIE89204.1 - 1.5e-20 73.5 0.0 5.1e-20 71.7 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE89204.1 - 2.4e-11 43.4 0.3 5.2e-11 42.3 0.2 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE89204.1 - 1.4e-10 40.6 0.4 3.6e-10 39.3 0.3 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.12 EIE89205.1 - 0.00024 21.1 0.1 0.0008 19.4 0.0 1.9 1 0 0 1 1 1 1 Retrotransposon gag protein DUF972 PF06156.8 EIE89206.1 - 1.8e-05 25.0 1.8 2.2e-05 24.7 1.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF972) TSC22 PF01166.13 EIE89206.1 - 0.00016 21.5 5.1 0.00019 21.3 2.9 1.6 1 1 0 1 1 1 1 TSC-22/dip/bun family DUF904 PF06005.7 EIE89206.1 - 0.0049 17.1 3.8 0.0079 16.4 2.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF904) Lebercilin PF15619.1 EIE89206.1 - 0.0054 16.1 1.9 0.0066 15.8 1.3 1.2 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease Syntaxin PF00804.20 EIE89206.1 - 0.014 15.5 0.7 0.017 15.2 0.5 1.2 1 0 0 1 1 1 0 Syntaxin HAP1_N PF04849.8 EIE89206.1 - 0.016 14.1 1.1 0.016 14.1 0.7 1.0 1 0 0 1 1 1 0 HAP1 N-terminal conserved region DUF2216 PF10226.4 EIE89206.1 - 0.02 14.4 0.4 0.022 14.2 0.3 1.1 1 0 0 1 1 1 0 Uncharacterized conserved proteins (DUF2216) bZIP_1 PF00170.16 EIE89206.1 - 0.023 14.6 1.6 0.023 14.6 1.1 1.5 2 0 0 2 2 2 0 bZIP transcription factor Jnk-SapK_ap_N PF09744.4 EIE89206.1 - 0.029 14.3 1.0 0.034 14.1 0.7 1.1 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF947 PF06102.7 EIE89206.1 - 0.03 14.1 0.2 0.031 14.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF947) IncA PF04156.9 EIE89206.1 - 0.038 13.5 1.2 0.047 13.2 0.9 1.2 1 0 0 1 1 1 0 IncA protein DUF4200 PF13863.1 EIE89206.1 - 0.039 13.9 3.9 0.05 13.5 2.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) BLOC1_2 PF10046.4 EIE89206.1 - 0.055 13.6 0.1 0.063 13.4 0.1 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DivIC PF04977.10 EIE89206.1 - 0.063 12.7 3.1 0.12 11.8 2.2 1.4 1 1 0 1 1 1 0 Septum formation initiator PEARLI-4 PF05278.7 EIE89206.1 - 0.067 12.5 0.0 0.075 12.4 0.0 1.0 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) Cep57_CLD_2 PF14197.1 EIE89206.1 - 0.11 12.4 3.7 0.21 11.5 2.6 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 Med9 PF07544.8 EIE89206.1 - 0.29 10.9 5.2 0.99 9.1 3.6 1.8 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 TMF_DNA_bd PF12329.3 EIE89206.1 - 0.97 9.2 4.8 1.9 8.3 3.3 1.5 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding rve PF00665.21 EIE89207.1 - 9e-23 80.6 0.0 2.7e-22 79.0 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE89207.1 - 1e-16 60.9 0.0 2.1e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE89207.1 - 8.2e-11 41.4 0.6 2.7e-10 39.7 0.4 2.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.1 EIE89207.1 - 0.00028 21.3 0.2 0.00086 19.7 0.2 1.9 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.5 EIE89207.1 - 0.00039 19.7 0.1 0.0011 18.3 0.1 1.9 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger UBN2_2 PF14227.1 EIE89207.1 - 0.01 15.4 0.4 0.3 10.6 0.0 2.7 3 0 0 3 3 3 0 gag-polypeptide of LTR copia-type rve_3 PF13683.1 EIE89207.1 - 0.032 13.7 0.0 0.09 12.3 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain Asp_protease PF09668.5 EIE89207.1 - 0.053 13.0 0.1 0.15 11.6 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease UBN2 PF14223.1 EIE89207.1 - 0.067 12.9 0.0 0.27 11.0 0.0 2.0 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type gag-asp_proteas PF13975.1 EIE89207.1 - 0.14 12.0 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DDE_3 PF13358.1 EIE89208.1 - 3.2e-17 62.6 0.1 6.1e-17 61.7 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE89208.1 - 2.4e-12 46.7 0.4 6.5e-12 45.3 0.3 1.8 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.1 EIE89208.1 - 0.0012 18.3 0.0 0.0033 17.0 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.1 EIE89208.1 - 0.0018 18.3 0.5 0.0037 17.3 0.3 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_7 PF02796.10 EIE89208.1 - 0.0021 17.8 0.2 0.081 12.7 0.0 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase rve PF00665.21 EIE89208.1 - 0.028 14.5 0.0 0.073 13.1 0.0 1.9 1 1 0 1 1 1 0 Integrase core domain rve PF00665.21 EIE89209.1 - 1.2e-17 64.0 0.0 8.4e-17 61.3 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 EIE89209.1 - 5.7e-17 61.7 0.2 1.3e-16 60.5 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE89209.1 - 5.2e-09 35.6 0.5 1.3e-08 34.3 0.3 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.1 EIE89209.1 - 8.3e-08 32.6 0.0 2.2e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 EIE89209.1 - 1.9e-06 27.7 0.1 1.5e-05 24.8 0.0 2.6 2 0 0 2 2 2 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EIE89209.1 - 0.00082 19.1 0.0 0.0019 17.9 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.12 EIE89209.1 - 0.0015 18.6 2.4 0.0051 16.8 0.0 3.2 4 0 0 4 4 4 1 Retrotransposon gag protein Asp_protease PF09668.5 EIE89209.1 - 0.013 15.1 0.2 0.1 12.1 0.1 2.4 2 0 0 2 2 2 0 Aspartyl protease Tudor-knot PF11717.3 EIE89209.1 - 0.07 12.8 2.9 0.086 12.5 0.1 2.5 2 0 0 2 2 2 0 RNA binding activity-knot of a chromodomain IncA PF04156.9 EIE89209.1 - 1.5 8.3 6.7 3.9 7.0 4.6 1.6 1 0 0 1 1 1 0 IncA protein DDE_3 PF13358.1 EIE89210.1 - 0.00018 21.2 0.0 0.0002 21.1 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease FAD_binding_3 PF01494.14 EIE89211.1 - 1.8e-72 244.3 0.1 2.4e-72 243.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EIE89211.1 - 8.4e-06 25.9 0.0 3e-05 24.1 0.0 1.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EIE89211.1 - 2.1e-05 23.7 0.0 0.00013 21.2 0.0 2.0 2 0 0 2 2 2 1 Thi4 family DAO PF01266.19 EIE89211.1 - 2.3e-05 23.5 0.4 0.0021 17.0 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIE89211.1 - 0.00041 20.3 0.3 0.001 19.0 0.0 1.8 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EIE89211.1 - 0.0005 20.0 0.0 0.0026 17.6 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Phe_hydrox_dim PF07976.7 EIE89211.1 - 0.00068 19.2 0.1 0.0025 17.4 0.0 2.0 2 1 0 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain SE PF08491.5 EIE89211.1 - 0.0011 17.8 0.0 0.0035 16.2 0.0 1.8 1 1 0 1 1 1 1 Squalene epoxidase Lycopene_cycl PF05834.7 EIE89211.1 - 0.0017 17.3 1.2 0.0082 15.1 0.8 2.0 1 1 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 EIE89211.1 - 0.0022 16.5 0.1 0.0038 15.7 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_7 PF13241.1 EIE89211.1 - 0.004 17.3 0.0 0.013 15.7 0.0 1.9 1 0 0 1 1 1 1 Putative NAD(P)-binding 3HCDH_N PF02737.13 EIE89211.1 - 0.015 14.9 0.0 0.029 14.0 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EIE89211.1 - 0.018 14.6 0.4 0.14 11.6 0.0 2.3 3 0 0 3 3 2 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.22 EIE89211.1 - 0.019 15.3 0.5 0.081 13.3 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EIE89211.1 - 0.028 13.2 0.1 0.066 12.0 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain Trp_halogenase PF04820.9 EIE89211.1 - 0.031 12.9 0.1 0.057 12.0 0.0 1.4 1 0 0 1 1 1 0 Tryptophan halogenase FAD_oxidored PF12831.2 EIE89211.1 - 0.15 11.1 2.9 0.56 9.2 2.0 1.8 1 1 0 1 1 1 0 FAD dependent oxidoreductase XdhC_C PF13478.1 EIE89211.1 - 0.16 12.3 1.0 2.3 8.5 0.0 3.1 4 0 0 4 4 4 0 XdhC Rossmann domain HIGH_NTase1 PF05636.6 EIE89212.1 - 0.022 13.7 0.9 0.03 13.3 0.7 1.1 1 0 0 1 1 1 0 HIGH Nucleotidyl Transferase DUF4247 PF14042.1 EIE89212.1 - 2.1 8.3 6.4 1.3 8.9 1.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4247) Rer1 PF03248.8 EIE89213.1 - 3.4e-43 147.2 0.3 3.8e-43 147.1 0.2 1.0 1 0 0 1 1 1 1 Rer1 family LTV PF04180.9 EIE89214.1 - 2.2e-50 172.4 29.1 1.5e-41 143.2 13.3 3.8 2 2 1 3 3 3 2 Low temperature viability protein DUF1743 PF08489.6 EIE89214.1 - 0.014 15.1 1.2 0.014 15.1 0.9 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1743) Syntaxin PF00804.20 EIE89215.1 - 0.00047 20.2 8.8 0.00047 20.2 6.1 5.0 2 1 2 4 4 4 1 Syntaxin Baculo_PEP_C PF04513.7 EIE89215.1 - 0.04 13.7 2.9 0.22 11.3 0.1 2.9 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TraF_2 PF13729.1 EIE89215.1 - 1.5 7.5 4.9 11 4.6 1.2 2.3 2 0 0 2 2 2 0 F plasmid transfer operon, TraF, protein DUF2730 PF10805.3 EIE89215.1 - 1.7 8.4 14.3 0.11 12.2 1.4 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF2730) DUF948 PF06103.6 EIE89215.1 - 2.2 8.2 10.5 0.18 11.7 0.5 3.6 3 2 1 4 4 4 0 Bacterial protein of unknown function (DUF948) Bacillus_HBL PF05791.6 EIE89215.1 - 2.7 7.3 23.7 1.7 7.9 0.2 4.1 2 2 2 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) Methyltransf_23 PF13489.1 EIE89217.1 - 1.4e-15 57.3 0.0 3.9e-15 55.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIE89217.1 - 3e-14 53.2 0.0 4.6e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIE89217.1 - 2.6e-13 49.8 0.0 8.4e-13 48.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIE89217.1 - 4.2e-11 42.4 0.0 1.2e-10 40.8 0.0 1.8 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EIE89217.1 - 2.3e-09 37.5 0.0 4.5e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIE89217.1 - 1.1e-07 32.4 0.0 2.9e-07 31.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIE89217.1 - 2.1e-06 28.1 0.0 4.3e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EIE89217.1 - 0.00068 18.7 0.0 0.02 13.9 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_8 PF05148.10 EIE89217.1 - 0.00086 18.9 0.0 0.0013 18.3 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_29 PF03141.11 EIE89217.1 - 0.0075 14.6 0.0 0.0085 14.4 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase TPMT PF05724.6 EIE89217.1 - 0.02 14.3 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) FmrO PF07091.6 EIE89217.1 - 0.1 11.5 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) BURP PF03181.10 EIE89217.1 - 0.12 11.5 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 BURP domain Glyco_trans_2_3 PF13632.1 EIE89218.1 - 4e-16 59.3 0.5 4e-16 59.3 0.4 1.9 2 0 0 2 2 2 1 Glycosyl transferase family group 2 PWWP PF00855.12 EIE89219.1 - 2.7e-19 69.1 0.1 2.7e-19 69.1 0.1 1.8 2 1 0 2 2 2 1 PWWP domain Med26 PF08711.6 EIE89219.1 - 9.8e-07 28.1 0.0 2.8e-06 26.7 0.0 1.8 2 0 0 2 2 2 1 TFIIS helical bundle-like domain 4HBT PF03061.17 EIE89220.1 - 1.5e-11 44.2 0.0 2e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.1 EIE89220.1 - 0.11 12.4 0.0 0.14 12.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) Methyltransf_16 PF10294.4 EIE89222.1 - 1.3e-05 24.7 0.0 2.5e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Glyco_hydro_18 PF00704.23 EIE89223.1 - 2.5e-62 211.3 5.9 2.9e-62 211.1 4.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Med5 PF08689.5 EIE89224.1 - 5.3e-10 37.6 6.6 7.5e-10 37.1 4.6 1.2 1 0 0 1 1 1 1 Mediator complex subunit Med5 ABC_membrane_2 PF06472.10 EIE89225.1 - 3.7e-21 75.4 1.5 7e-21 74.5 0.4 1.7 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EIE89225.1 - 7.2e-09 36.0 0.0 2.4e-08 34.3 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 EIE89225.1 - 2.9e-06 27.4 7.6 8.6e-06 25.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 EIE89225.1 - 5.4e-05 23.6 3.9 0.0012 19.2 0.3 2.4 1 1 1 2 2 2 1 AAA domain T2SE PF00437.15 EIE89225.1 - 0.001 18.0 0.0 0.0015 17.4 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.1 EIE89225.1 - 0.0011 18.9 0.1 0.0027 17.7 0.0 1.6 2 0 0 2 2 1 1 AAA ATPase domain MutS_V PF00488.16 EIE89225.1 - 0.0037 16.7 0.0 0.006 16.0 0.0 1.3 1 0 0 1 1 1 1 MutS domain V AAA_29 PF13555.1 EIE89225.1 - 0.0042 16.5 0.0 0.0077 15.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain NACHT PF05729.7 EIE89225.1 - 0.0044 16.6 0.0 0.0087 15.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_19 PF13245.1 EIE89225.1 - 0.0045 16.7 0.0 0.0092 15.7 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EIE89225.1 - 0.012 15.2 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.14 EIE89225.1 - 0.013 14.7 0.0 0.033 13.4 0.0 1.6 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_28 PF13521.1 EIE89225.1 - 0.018 14.9 0.0 0.041 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EIE89225.1 - 0.027 15.3 0.4 0.083 13.7 0.0 2.0 3 0 0 3 3 2 0 AAA domain AAA_22 PF13401.1 EIE89225.1 - 0.028 14.5 0.1 0.083 13.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EIE89225.1 - 0.028 13.8 0.0 0.042 13.3 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Mg_chelatase PF01078.16 EIE89225.1 - 0.031 13.4 0.0 0.054 12.6 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 EIE89225.1 - 0.043 13.7 0.1 0.17 11.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.1 EIE89225.1 - 0.053 13.5 0.0 0.26 11.3 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_18 PF13238.1 EIE89225.1 - 0.073 13.3 0.4 0.33 11.2 0.0 2.2 3 0 0 3 3 3 0 AAA domain Miro PF08477.8 EIE89225.1 - 0.078 13.4 0.0 0.21 12.1 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein cobW PF02492.14 EIE89225.1 - 0.12 11.8 0.2 0.26 10.7 0.0 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain 2OG-FeII_Oxy PF03171.15 EIE89226.1 - 0.00017 21.8 0.0 0.00042 20.5 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-Fe_Oxy_2 PF10014.4 EIE89226.1 - 0.04 13.2 0.0 0.12 11.6 0.0 1.8 2 0 0 2 2 2 0 2OG-Fe dioxygenase Hce2 PF14856.1 EIE89226.1 - 0.12 12.2 0.6 1.2 9.1 0.1 2.2 2 0 0 2 2 2 0 Pathogen effector; putative necrosis-inducing factor PAP_central PF04928.12 EIE89227.1 - 4.1e-33 114.2 1.0 1.1e-32 112.8 0.7 1.6 1 1 0 1 1 1 1 Poly(A) polymerase central domain DUF484 PF04340.7 EIE89227.1 - 0.04 13.3 0.1 0.057 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF484 Bap31 PF05529.7 EIE89228.1 - 1.4e-06 27.8 9.5 1.9e-06 27.5 6.6 1.2 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like Cluap1 PF10234.4 EIE89228.1 - 0.0035 16.6 12.9 0.0041 16.3 8.9 1.0 1 0 0 1 1 1 1 Clusterin-associated protein-1 IncA PF04156.9 EIE89228.1 - 0.0087 15.6 14.0 0.011 15.4 9.7 1.1 1 0 0 1 1 1 1 IncA protein NPV_P10 PF05531.7 EIE89228.1 - 0.04 14.1 1.9 0.04 14.1 1.3 2.0 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF3540 PF12059.3 EIE89228.1 - 0.084 12.5 4.9 0.21 11.2 3.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3540) DUF4239 PF14023.1 EIE89228.1 - 0.25 10.6 4.2 0.32 10.3 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) DUF3090 PF11290.3 EIE89228.1 - 0.35 10.3 2.0 0.41 10.0 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3090) APG6 PF04111.7 EIE89228.1 - 0.55 9.2 11.3 0.59 9.1 7.9 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Z1 PF10593.4 EIE89228.1 - 1.2 8.2 7.3 1.5 7.9 5.0 1.1 1 0 0 1 1 1 0 Z1 domain Fib_alpha PF08702.5 EIE89228.1 - 1.5 8.9 14.1 2.6 8.1 9.8 1.4 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family SID-1_RNA_chan PF13965.1 EIE89228.1 - 2.5 6.1 6.2 2.7 6.0 4.3 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 SAC3_GANP PF03399.11 EIE89231.1 - 6.8e-55 185.7 2.3 1.6e-54 184.5 1.6 1.7 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family IFN-gamma PF00714.12 EIE89232.1 - 0.061 13.1 0.1 0.12 12.2 0.1 1.7 1 1 0 1 1 1 0 Interferon gamma UPF0093 PF03653.8 EIE89232.1 - 0.13 12.2 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0093) RasGEF PF00617.14 EIE89233.1 - 5.2e-41 140.4 0.2 6.1e-22 78.2 0.0 3.0 1 1 1 2 2 2 2 RasGEF domain RasGEF_N PF00618.15 EIE89233.1 - 1.5e-26 92.4 1.1 6.9e-26 90.3 0.3 2.6 2 0 0 2 2 2 1 RasGEF N-terminal motif WW PF00397.21 EIE89233.1 - 5.2e-08 32.6 6.5 1.6e-07 31.0 0.1 2.6 2 0 0 2 2 2 1 WW domain NESP55 PF06390.7 EIE89233.1 - 0.37 10.1 10.8 0.78 9.0 7.5 1.4 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) Proteasome PF00227.21 EIE89235.1 - 3e-60 202.7 0.4 2e-59 200.0 0.2 2.0 2 0 0 2 2 2 1 Proteasome subunit Proteasome_A_N PF10584.4 EIE89235.1 - 3e-14 51.9 0.0 5.8e-14 51.0 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Polyketide_cyc PF03364.15 EIE89235.1 - 5.2e-08 32.9 0.0 9.5e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Vps26 PF03643.10 EIE89237.1 - 0.082 11.6 0.0 0.19 10.5 0.0 1.4 1 1 0 1 1 1 0 Vacuolar protein sorting-associated protein 26 XAP5 PF04921.9 EIE89237.1 - 0.085 12.4 4.3 0.16 11.4 3.0 1.4 1 0 0 1 1 1 0 XAP5, circadian clock regulator Exo_endo_phos PF03372.18 EIE89239.1 - 5.4e-06 26.5 0.0 7.4e-06 26.0 0.0 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-RVT PF13966.1 EIE89239.1 - 0.044 14.0 0.2 0.085 13.1 0.1 1.4 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase DUF1212 PF06738.7 EIE89240.1 - 1.8e-33 115.6 16.3 9.6e-33 113.2 0.0 2.6 3 0 0 3 3 3 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 EIE89240.1 - 7.6e-07 29.1 8.0 7.6e-07 29.1 5.6 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3815) B-block_TFIIIC PF04182.7 EIE89241.1 - 3.3e-10 39.6 0.4 3.3e-10 39.6 0.3 2.5 2 0 0 2 2 2 1 B-block binding subunit of TFIIIC polyprenyl_synt PF00348.12 EIE89242.1 - 3.3e-31 108.1 1.0 7.1e-31 107.0 0.7 1.5 1 1 0 1 1 1 1 Polyprenyl synthetase Kelch_4 PF13418.1 EIE89242.1 - 3.5e-14 52.2 13.6 0.00019 21.1 0.0 6.4 6 1 0 6 6 6 3 Galactose oxidase, central domain Kelch_3 PF13415.1 EIE89242.1 - 3e-10 39.9 14.5 0.00033 20.7 0.1 6.1 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_6 PF13964.1 EIE89242.1 - 5.2e-10 39.0 19.6 0.0013 18.7 0.1 7.3 6 1 1 7 7 7 2 Kelch motif Kelch_5 PF13854.1 EIE89242.1 - 4.2e-08 32.9 5.6 0.088 12.7 0.0 5.6 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.20 EIE89242.1 - 1.6e-07 30.7 1.6 0.077 12.5 0.0 5.5 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.10 EIE89242.1 - 0.00025 20.6 9.0 0.015 15.0 0.0 6.0 7 0 0 7 7 7 1 Kelch motif HEPPP_synt_1 PF07307.6 EIE89242.1 - 0.0072 15.7 0.6 0.016 14.6 0.2 1.7 2 0 0 2 2 2 1 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 SQS_PSY PF00494.14 EIE89242.1 - 0.1 11.8 0.2 0.18 11.1 0.1 1.3 1 0 0 1 1 1 0 Squalene/phytoene synthase RabGAP-TBC PF00566.13 EIE89243.1 - 1.4e-23 83.4 6.1 6.5e-17 61.7 0.3 2.2 1 1 1 2 2 2 2 Rab-GTPase-TBC domain NusB PF01029.13 EIE89243.1 - 0.091 12.7 0.8 0.17 11.8 0.5 1.5 1 0 0 1 1 1 0 NusB family Synaptobrevin PF00957.16 EIE89244.1 - 5.3e-25 86.8 0.3 6e-25 86.6 0.2 1.0 1 0 0 1 1 1 1 Synaptobrevin ETRAMP PF09716.5 EIE89244.1 - 0.0012 18.7 0.0 0.0012 18.7 0.0 1.1 1 0 0 1 1 1 1 Malarial early transcribed membrane protein (ETRAMP) TauE PF01925.14 EIE89244.1 - 0.03 13.7 0.2 0.034 13.5 0.1 1.1 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE DUF2077 PF09850.4 EIE89244.1 - 0.075 12.4 0.0 0.081 12.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2077) 4HB_MCP_1 PF12729.2 EIE89244.1 - 0.44 9.8 2.0 0.61 9.4 0.5 1.8 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction NUDIX PF00293.23 EIE89246.1 - 3.6e-17 62.2 0.0 6.1e-17 61.5 0.0 1.4 1 1 0 1 1 1 1 NUDIX domain PAP2 PF01569.16 EIE89247.1 - 4.6e-11 42.5 15.4 4.5e-10 39.2 10.7 2.4 1 1 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.1 EIE89247.1 - 8.1e-06 25.4 3.4 1.8e-05 24.3 2.4 1.6 1 0 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.1 EIE89247.1 - 7.8 6.8 13.8 0.34 11.2 3.7 2.7 2 1 1 3 3 3 0 PAP2 superfamily C-terminal Acetyltransf_1 PF00583.19 EIE89248.1 - 3.8e-16 58.8 0.0 4.8e-16 58.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EIE89248.1 - 3e-09 36.8 0.1 5.5e-09 36.0 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EIE89248.1 - 6.8e-07 29.2 0.0 8.4e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EIE89248.1 - 9e-07 28.5 0.0 1.4e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EIE89248.1 - 2.6e-05 24.3 0.0 3.1e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EIE89248.1 - 3.8e-05 23.6 0.1 4.6e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EIE89248.1 - 0.00026 21.1 0.0 0.00054 20.1 0.0 1.5 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EIE89248.1 - 0.0045 16.8 0.0 0.0089 15.8 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EIE89248.1 - 0.021 14.7 0.1 0.036 13.9 0.0 1.5 1 1 0 1 1 1 0 GCN5-related N-acetyl-transferase zf-RING_2 PF13639.1 EIE89250.1 - 2.5e-12 46.4 7.4 2.5e-12 46.4 5.2 1.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EIE89250.1 - 5.2e-09 35.9 8.2 1.2e-08 34.8 5.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIE89250.1 - 1.3e-08 34.2 6.3 1.3e-08 34.2 4.3 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIE89250.1 - 3.2e-07 29.9 5.7 5.8e-07 29.1 3.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EIE89250.1 - 1.3e-06 27.9 7.8 2.4e-06 27.1 5.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EIE89250.1 - 6.3e-05 23.0 7.7 0.00026 21.0 5.5 1.9 1 1 1 2 2 2 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 EIE89250.1 - 0.0057 16.5 7.7 0.013 15.3 5.4 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EIE89250.1 - 0.076 12.7 0.4 0.076 12.7 0.2 3.0 3 0 0 3 3 3 0 RING-type zinc-finger zf-RING_4 PF14570.1 EIE89250.1 - 0.72 9.4 9.7 1.6 8.3 6.7 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 EIE89250.1 - 0.86 9.4 7.3 2.7 7.8 5.1 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-P11 PF03854.9 EIE89250.1 - 1 8.9 8.3 2.8 7.4 5.8 1.8 1 0 0 1 1 1 0 P-11 zinc finger Prok-RING_4 PF14447.1 EIE89250.1 - 4.3 6.9 7.6 10 5.7 5.3 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 RNA_pol_Rpc4 PF05132.9 EIE89252.1 - 2 8.4 7.9 3.6 7.5 5.5 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 Pkinase PF00069.20 EIE89253.1 - 8.1e-40 136.6 0.0 8.9e-40 136.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE89253.1 - 5.2e-16 58.5 0.0 6.8e-16 58.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIE89253.1 - 6.4e-05 22.7 0.0 0.0015 18.3 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EIE89253.1 - 0.014 14.1 0.1 0.021 13.6 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.9 EIE89253.1 - 0.062 12.3 0.4 0.12 11.3 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EIE89253.1 - 0.1 12.1 0.1 0.19 11.2 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase VHS PF00790.14 EIE89254.1 - 1.4e-31 108.9 0.1 1.3e-30 105.8 0.0 2.4 2 0 0 2 2 2 1 VHS domain Alpha_adaptinC2 PF02883.15 EIE89254.1 - 7.8e-19 68.0 2.2 2.2e-18 66.6 1.5 1.8 1 0 0 1 1 1 1 Adaptin C-terminal domain GAT PF03127.9 EIE89254.1 - 4.9e-14 52.1 0.3 2.4e-13 49.9 0.2 2.2 1 0 0 1 1 1 1 GAT domain RBM39linker PF15519.1 EIE89254.1 - 0.13 12.5 1.5 0.6 10.4 1.0 2.1 1 0 0 1 1 1 0 linker between RRM2 and RRM3 domains in RBM39 protein DUF897 PF05982.7 EIE89254.1 - 2.3 6.9 4.1 0.32 9.7 0.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF897) Asp PF00026.18 EIE89256.1 - 3.5e-114 381.3 0.0 4.2e-114 381.0 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIE89256.1 - 1.2e-10 41.6 0.0 6.7e-10 39.1 0.0 2.1 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EIE89256.1 - 9.1e-05 22.0 0.0 0.00044 19.8 0.0 2.2 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 EIE89256.1 - 0.0016 18.9 0.2 1.1 9.8 0.0 3.0 3 1 0 3 3 3 2 Aspartyl protease CYSTM PF12734.2 EIE89257.1 - 0.00031 20.7 29.8 0.00031 20.7 20.6 4.0 2 2 1 3 3 3 1 Cysteine-rich TM module stress tolerance Pex14_N PF04695.8 EIE89257.1 - 1.5 8.8 9.5 2.3 8.2 6.6 1.4 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Formyl_trans_N PF00551.14 EIE89259.1 - 5.5e-28 97.7 0.0 6.3e-28 97.5 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase Ribosomal_L37e PF01907.14 EIE89260.1 - 5.5e-26 90.1 12.6 1.1e-25 89.2 8.7 1.5 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.2 EIE89260.1 - 0.00027 20.6 2.9 0.00043 20.0 2.0 1.3 1 0 0 1 1 1 1 Double zinc ribbon SelR PF01641.13 EIE89260.1 - 0.0077 15.9 1.2 0.011 15.3 0.9 1.5 1 1 0 1 1 1 1 SelR domain HypA PF01155.14 EIE89260.1 - 0.029 14.0 1.0 0.041 13.5 0.7 1.2 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-RING_5 PF14634.1 EIE89260.1 - 0.034 13.8 4.0 0.052 13.2 2.8 1.3 1 0 0 1 1 1 0 zinc-RING finger domain C1_1 PF00130.17 EIE89260.1 - 0.046 13.4 3.6 0.084 12.6 2.5 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Ribosomal_S14 PF00253.16 EIE89260.1 - 0.16 11.3 6.9 0.83 9.0 0.1 2.5 1 1 1 2 2 2 0 Ribosomal protein S14p/S29e Ogr_Delta PF04606.7 EIE89260.1 - 0.21 11.2 3.3 0.66 9.6 0.2 2.3 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger GFA PF04828.9 EIE89260.1 - 0.35 10.8 4.3 1.6 8.7 2.5 2.1 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zf-ribbon_3 PF13248.1 EIE89260.1 - 0.48 9.6 4.1 2.8 7.2 3.0 1.9 1 1 1 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 EIE89260.1 - 0.61 9.6 5.3 6.9 6.2 3.7 2.1 1 1 1 2 2 2 0 zinc-ribbon domain zf-C3HC4_2 PF13923.1 EIE89260.1 - 0.62 10.1 5.1 0.98 9.4 3.5 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIE89260.1 - 0.9 9.2 5.1 1.4 8.6 3.5 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) YhfH PF14149.1 EIE89260.1 - 3.1 7.6 6.0 3.1 7.6 1.3 2.2 1 1 1 2 2 2 0 YhfH-like protein RNA_POL_M_15KD PF02150.11 EIE89260.1 - 4.3 7.1 5.9 32 4.3 4.2 2.0 1 1 0 1 1 1 0 RNA polymerases M/15 Kd subunit zf-HYPF PF07503.7 EIE89260.1 - 8.8 5.8 7.6 5.2 6.5 3.1 2.1 2 1 1 3 3 3 0 HypF finger zf-CCCH PF00642.19 EIE89262.1 - 1.2e-08 34.4 37.1 0.00037 20.1 4.5 5.3 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EIE89262.1 - 0.011 15.6 1.4 0.011 15.6 1.0 4.1 4 0 0 4 4 4 0 Zinc finger C-x8-C-x5-C-x3-H type PPP4R2 PF09184.6 EIE89262.1 - 0.51 9.8 16.7 1.7 8.0 9.7 2.2 2 0 0 2 2 2 0 PPP4R2 Glyoxalase PF00903.20 EIE89264.1 - 3.2e-22 78.8 0.0 3.9e-22 78.5 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EIE89264.1 - 7.7e-15 55.4 0.0 1.1e-14 54.9 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 EIE89264.1 - 2.2e-10 40.4 0.0 1.9e-09 37.4 0.0 2.0 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 EIE89264.1 - 0.0029 17.5 0.0 0.0078 16.1 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase-like domain CppA_N PF14506.1 EIE89264.1 - 0.13 11.9 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 CppA N-terminal T_Ag_DNA_bind PF02217.11 EIE89265.1 - 0.081 13.3 0.6 3.3 8.1 0.0 2.4 2 0 0 2 2 2 0 Origin of replication binding protein Cobl PF09469.5 EIE89265.1 - 3.1 7.8 7.3 1.5 8.8 3.1 2.0 2 0 0 2 2 2 0 Cordon-bleu ubiquitin-like domain Na_H_Exchanger PF00999.16 EIE89267.1 - 4.8e-49 166.8 22.9 4.5e-48 163.6 15.9 1.9 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family Vma12 PF11712.3 EIE89267.1 - 1.6 8.4 5.8 0.5 10.0 0.3 2.6 2 1 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase SPC12 PF06645.8 EIE89267.1 - 6.3 6.6 8.6 0.48 10.2 0.3 3.0 3 0 0 3 3 3 0 Microsomal signal peptidase 12 kDa subunit (SPC12) WW PF00397.21 EIE89268.1 - 8.8e-09 35.0 1.6 8.8e-09 35.0 1.1 2.2 2 0 0 2 2 2 1 WW domain HMA PF00403.21 EIE89269.1 - 5.6e-51 170.5 2.5 2.5e-13 49.9 0.0 4.7 4 0 0 4 4 4 4 Heavy-metal-associated domain E1-E2_ATPase PF00122.15 EIE89269.1 - 3.1e-48 163.8 1.1 8.6e-48 162.3 0.8 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EIE89269.1 - 1.5e-40 139.9 0.8 3.7e-40 138.6 0.1 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EIE89269.1 - 3e-14 53.6 0.0 9.4e-14 52.0 0.0 1.9 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EIE89269.1 - 7.4e-05 22.4 0.2 0.031 13.8 0.0 2.6 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase DUF2997 PF11211.3 EIE89269.1 - 0.15 11.4 2.0 3.8 6.9 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2997) zf-MYND PF01753.13 EIE89270.1 - 9.4e-09 35.0 18.1 3.2e-07 30.1 6.9 2.6 2 0 0 2 2 2 2 MYND finger zf-ribbon_3 PF13248.1 EIE89270.1 - 0.0019 17.3 3.0 0.0019 17.3 2.0 2.4 2 0 0 2 2 2 1 zinc-ribbon domain TPR_1 PF00515.23 EIE89270.1 - 0.086 12.4 0.1 0.2 11.2 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Siva PF05458.7 EIE89270.1 - 3.5 7.1 17.7 0.36 10.3 3.9 2.8 3 0 0 3 3 3 0 Cd27 binding protein (Siva) zinc_ribbon_2 PF13240.1 EIE89270.1 - 8.4 6.0 11.1 1.6 8.3 0.2 3.8 4 0 0 4 4 4 0 zinc-ribbon domain Ribosomal_L31 PF01197.13 EIE89272.1 - 0.0001 22.2 0.1 0.00017 21.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L31 DUF1838 PF08894.6 EIE89273.1 - 1.8e-13 50.3 0.0 2.2e-13 49.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1838) APG17 PF04108.7 EIE89275.1 - 1.5e-26 93.1 18.9 1.5e-15 56.9 1.5 2.3 1 1 1 2 2 2 2 Autophagy protein Apg17 COX14 PF14880.1 EIE89276.1 - 0.035 13.7 0.1 0.042 13.4 0.1 1.2 1 0 0 1 1 1 0 Cytochrome oxidase c assembly Herpes_UL47 PF03362.8 EIE89276.1 - 0.13 10.5 0.0 0.13 10.5 0.0 1.0 1 0 0 1 1 1 0 Herpesvirus UL47 protein Snf7 PF03357.16 EIE89277.1 - 4.1e-41 140.1 10.0 4.1e-41 140.1 6.9 1.9 1 1 1 2 2 2 1 Snf7 DASH_Dad4 PF08650.5 EIE89277.1 - 0.013 15.4 1.0 0.026 14.4 0.5 1.6 1 1 0 1 1 1 0 DASH complex subunit Dad4 TraF_2 PF13729.1 EIE89277.1 - 0.031 13.1 1.8 0.04 12.7 0.7 1.5 1 1 0 1 1 1 0 F plasmid transfer operon, TraF, protein Upf2 PF04050.9 EIE89277.1 - 0.079 12.7 4.2 0.11 12.3 2.9 1.2 1 0 0 1 1 1 0 Up-frameshift suppressor 2 DUF1425 PF07233.7 EIE89279.1 - 0.039 13.4 0.1 0.048 13.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1425) TIP49 PF06068.8 EIE89280.1 - 1.9e-184 612.9 4.4 2.3e-184 612.7 3.0 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 EIE89280.1 - 3.7e-08 33.6 3.6 4.3e-05 23.7 0.0 3.3 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EIE89280.1 - 1.2e-07 31.0 4.3 0.0003 19.8 0.0 3.2 2 1 1 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus DnaB_C PF03796.10 EIE89280.1 - 1.9e-06 26.9 0.2 3.6e-06 26.0 0.1 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_22 PF13401.1 EIE89280.1 - 4.7e-05 23.5 1.6 0.1 12.7 0.0 3.2 2 1 1 3 3 3 2 AAA domain AAA_5 PF07728.9 EIE89280.1 - 8.6e-05 22.2 0.1 0.11 12.1 0.0 3.0 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EIE89280.1 - 0.00022 20.6 0.0 0.0013 18.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EIE89280.1 - 0.00025 20.9 0.3 0.9 9.4 0.0 3.3 3 1 0 3 3 3 2 AAA domain Mg_chelatase PF01078.16 EIE89280.1 - 0.00029 20.0 1.5 0.02 14.0 0.5 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 EIE89280.1 - 0.00084 19.3 0.0 0.015 15.2 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain Sigma54_activat PF00158.21 EIE89280.1 - 0.0022 17.5 0.9 3.8 6.9 0.0 3.4 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_19 PF13245.1 EIE89280.1 - 0.0046 16.6 0.1 0.014 15.1 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 EIE89280.1 - 0.022 14.3 0.1 0.054 13.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EIE89280.1 - 0.03 14.2 0.0 0.086 12.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.12 EIE89280.1 - 0.034 13.0 0.1 0.071 11.9 0.1 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 FtsK_SpoIIIE PF01580.13 EIE89280.1 - 0.24 10.8 2.0 3 7.2 0.1 2.9 3 0 0 3 3 3 0 FtsK/SpoIIIE family HLH PF00010.21 EIE89285.1 - 4e-15 55.2 0.3 1.2e-14 53.7 0.2 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Med11 PF10280.4 EIE89285.1 - 0.11 12.5 0.2 0.19 11.7 0.2 1.4 1 0 0 1 1 1 0 Mediator complex protein Nro1 PF12753.2 EIE89288.1 - 8.1e-29 100.7 22.2 1.5e-21 76.8 2.4 2.0 2 0 0 2 2 2 2 Nuclear pore complex subunit Nro1 TPR_16 PF13432.1 EIE89288.1 - 1.1e-07 32.3 4.8 0.0025 18.4 0.0 4.3 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 EIE89288.1 - 8.5e-05 22.4 1.4 0.97 9.7 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EIE89288.1 - 0.00071 19.4 6.8 0.57 10.1 0.1 4.3 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 EIE89288.1 - 0.00075 19.0 7.0 0.1 12.2 0.1 3.9 3 1 0 3 3 3 1 TPR repeat TPR_19 PF14559.1 EIE89288.1 - 0.0098 16.2 7.6 1 9.7 0.0 4.6 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EIE89288.1 - 0.037 14.6 6.5 1.6 9.5 0.0 4.5 4 1 0 4 4 4 0 Tetratricopeptide repeat DUF4054 PF13262.1 EIE89288.1 - 0.14 12.4 2.4 6.8 6.9 0.0 3.6 2 2 1 3 3 3 0 Protein of unknown function (DUF4054) Nuc_deoxyrib_tr PF05014.10 EIE89288.1 - 0.76 9.6 3.8 0.88 9.4 0.3 2.4 2 1 0 2 2 2 0 Nucleoside 2-deoxyribosyltransferase DUF936 PF06075.7 EIE89288.1 - 1.9 7.3 10.4 0.084 11.7 3.2 1.6 2 0 0 2 2 2 0 Plant protein of unknown function (DUF936) tRNA-synt_2 PF00152.15 EIE89289.1 - 8.4e-82 274.6 0.3 8e-81 271.4 0.2 2.1 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EIE89289.1 - 2.4e-12 46.5 0.0 5.2e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EIE89289.1 - 1.7e-09 37.2 0.1 0.00021 20.5 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti-like PF12869.2 EIE89289.1 - 0.11 11.9 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 tRNA_anti-like Ribosomal_60s PF00428.14 EIE89289.1 - 0.42 11.0 12.9 0.98 9.8 8.9 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein SPRY PF00622.23 EIE89290.1 - 3.7e-09 36.7 0.1 2.2e-08 34.2 0.0 2.2 2 0 0 2 2 2 1 SPRY domain LAP1C PF05609.7 EIE89290.1 - 0.059 12.0 0.7 0.088 11.4 0.5 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Actin PF00022.14 EIE89291.1 - 1.5e-162 540.5 0.0 1.7e-162 540.3 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 EIE89291.1 - 0.081 13.3 0.0 0.2 12.0 0.0 1.7 1 1 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) zf-C2H2_4 PF13894.1 EIE89292.1 - 0.00034 20.7 21.1 0.044 14.1 0.2 4.3 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EIE89292.1 - 0.012 15.8 19.2 0.21 11.9 1.0 4.3 4 0 0 4 4 4 0 Zinc finger, C2H2 type DUF629 PF04780.7 EIE89292.1 - 0.065 11.7 9.9 0.29 9.6 0.2 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF629) Evr1_Alr PF04777.8 EIE89292.1 - 0.093 12.6 3.6 4.3 7.2 0.3 2.7 2 1 0 2 2 2 0 Erv1 / Alr family zf-C2H2_2 PF12756.2 EIE89292.1 - 0.16 12.1 6.8 5.3 7.2 0.3 3.1 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 EIE89292.1 - 0.4 10.9 4.8 8.7 6.7 0.1 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.1 EIE89292.1 - 1.9 8.9 24.3 0.31 11.4 0.7 5.4 6 0 0 6 6 6 0 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EIE89292.1 - 3.5 7.8 7.9 62 3.9 1.1 3.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met2 PF12907.2 EIE89292.1 - 6.1 6.9 12.2 9.8 6.2 0.8 3.4 3 1 1 4 4 4 0 Zinc-binding Helicase_C PF00271.26 EIE89293.1 - 3.3e-19 68.5 0.1 9.6e-19 67.0 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIE89293.1 - 3.3e-19 69.4 0.4 2.3e-18 66.7 0.0 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EIE89293.1 - 1.8e-18 66.5 0.0 5.1e-18 65.1 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase VHS PF00790.14 EIE89294.1 - 2.8e-32 111.3 0.1 5.9e-32 110.2 0.1 1.5 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.23 EIE89294.1 - 3.3e-17 61.5 0.1 6.5e-17 60.6 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EIE89294.1 - 6.9e-17 60.7 0.3 1.4e-16 59.7 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EIE89294.1 - 1.9e-13 49.6 0.3 5e-13 48.3 0.2 1.7 2 0 0 2 2 2 1 Variant SH3 domain UIM PF02809.15 EIE89294.1 - 0.0024 17.2 4.1 0.0048 16.3 2.1 2.2 2 0 0 2 2 2 1 Ubiquitin interaction motif GAT PF03127.9 EIE89294.1 - 0.0097 15.8 1.4 0.027 14.4 1.0 1.7 1 0 0 1 1 1 1 GAT domain HEAT_2 PF13646.1 EIE89294.1 - 0.07 13.4 0.4 3.5 7.9 0.1 2.5 2 0 0 2 2 2 0 HEAT repeats NdhO PF11910.3 EIE89295.1 - 0.1 12.2 0.0 0.78 9.4 0.0 2.0 2 0 0 2 2 2 0 Cyanobacterial and plant NDH-1 subunit O Ank_2 PF12796.2 EIE89296.1 - 1.2e-13 51.1 0.1 2.6e-13 50.1 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) TIG PF01833.19 EIE89296.1 - 1.5e-12 47.2 0.2 3e-12 46.3 0.1 1.5 1 0 0 1 1 1 1 IPT/TIG domain Ank PF00023.25 EIE89296.1 - 3.9e-12 45.3 1.3 3.9e-05 23.2 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 EIE89296.1 - 2e-11 43.7 1.1 9.6e-07 28.8 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIE89296.1 - 5e-10 38.6 0.3 0.00016 21.5 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 EIE89296.1 - 9.6e-10 38.7 0.6 2.2e-09 37.5 0.4 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) LisH PF08513.6 EIE89297.1 - 2.4e-05 23.9 0.3 4e-05 23.2 0.2 1.4 1 0 0 1 1 1 1 LisH Ribosomal_L28 PF00830.14 EIE89300.1 - 1.2e-22 79.4 1.5 1.9e-22 78.8 1.1 1.3 1 0 0 1 1 1 1 Ribosomal L28 family Coprogen_oxidas PF01218.13 EIE89301.1 - 3e-121 403.5 0.0 3.4e-121 403.3 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase RNB PF00773.14 EIE89302.1 - 6.4e-62 209.7 0.1 1e-61 209.0 0.0 1.4 1 0 0 1 1 1 1 RNB domain Inhibitor_I9 PF05922.11 EIE89303.1 - 1.2e-09 38.5 0.0 1.6e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase inhibitor I9 Prefoldin_2 PF01920.15 EIE89304.1 - 1.8e-25 88.7 6.0 2e-25 88.6 4.1 1.0 1 0 0 1 1 1 1 Prefoldin subunit UBN2 PF14223.1 EIE89304.1 - 0.00044 20.0 0.7 0.18 11.5 0.1 2.1 2 0 0 2 2 2 2 gag-polypeptide of LTR copia-type DUF2935 PF11155.3 EIE89304.1 - 0.0041 17.2 0.5 0.0058 16.7 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2935) IncA PF04156.9 EIE89304.1 - 0.0048 16.5 2.9 0.0072 15.9 2.0 1.2 1 0 0 1 1 1 1 IncA protein DASH_Spc34 PF08657.5 EIE89304.1 - 0.0092 15.6 2.5 0.0092 15.6 1.8 1.8 1 1 1 2 2 2 1 DASH complex subunit Spc34 EzrA PF06160.7 EIE89304.1 - 0.018 13.2 3.3 0.24 9.5 0.0 2.0 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA TBPIP PF07106.8 EIE89304.1 - 0.018 14.5 0.7 0.018 14.5 0.5 1.9 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) BLOC1_2 PF10046.4 EIE89304.1 - 0.037 14.1 5.7 0.092 12.8 0.7 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 UBN2_2 PF14227.1 EIE89304.1 - 0.039 13.4 0.4 0.13 11.8 0.2 1.8 1 1 1 2 2 2 0 gag-polypeptide of LTR copia-type TMF_TATA_bd PF12325.3 EIE89304.1 - 0.046 13.4 3.8 1.2 8.8 0.7 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Tho2 PF11262.3 EIE89304.1 - 0.048 12.7 2.5 0.16 10.9 0.5 1.9 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 GrpE PF01025.14 EIE89304.1 - 0.075 12.5 3.0 1.9 8.0 0.1 2.1 2 0 0 2 2 2 0 GrpE HJURP_C PF12347.3 EIE89304.1 - 0.084 12.4 0.8 0.21 11.2 0.0 2.0 2 1 1 3 3 3 0 Holliday junction regulator protein family C-terminal repeat Tup_N PF08581.5 EIE89304.1 - 0.093 12.9 3.4 0.1 12.8 0.5 2.0 2 0 0 2 2 2 0 Tup N-terminal DASH_Dad3 PF08656.5 EIE89304.1 - 0.11 12.2 3.0 0.11 12.1 0.7 1.8 2 0 0 2 2 2 0 DASH complex subunit Dad3 IFT57 PF10498.4 EIE89304.1 - 0.11 11.1 6.9 0.62 8.7 4.8 1.8 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 DUF2089 PF09862.4 EIE89304.1 - 0.11 12.2 1.7 2.4 7.9 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2089) DUF3552 PF12072.3 EIE89304.1 - 0.25 10.5 6.3 0.049 12.8 2.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) Nnf1 PF03980.9 EIE89304.1 - 0.26 11.3 2.9 0.57 10.1 0.5 2.2 2 1 1 3 3 3 0 Nnf1 Prefoldin PF02996.12 EIE89304.1 - 0.27 10.8 4.3 7.6 6.2 3.0 2.1 1 1 0 1 1 1 0 Prefoldin subunit Fib_alpha PF08702.5 EIE89304.1 - 0.4 10.7 3.3 0.92 9.6 2.3 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family TMF_DNA_bd PF12329.3 EIE89304.1 - 1.6 8.5 6.1 0.66 9.8 1.7 1.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DivIVA PF05103.8 EIE89304.1 - 1.7 8.6 6.5 0.9 9.5 1.3 2.0 2 0 0 2 2 2 0 DivIVA protein WD40 PF00400.27 EIE89305.1 - 8e-06 25.5 0.2 8.4e-05 22.3 0.0 2.5 2 0 0 2 2 2 1 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EIE89305.1 - 0.09 12.3 0.1 4 7.0 0.0 3.3 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain BBS2_N PF14781.1 EIE89305.1 - 0.13 11.8 0.2 31 4.2 0.0 3.5 5 0 0 5 5 5 0 Ciliary BBSome complex subunit 2, N-terminal RabGAP-TBC PF00566.13 EIE89306.1 - 3.3e-54 183.6 0.4 3.3e-54 183.6 0.3 2.2 2 0 0 2 2 2 1 Rab-GTPase-TBC domain APG6 PF04111.7 EIE89306.1 - 0.015 14.3 23.3 0.14 11.1 8.8 3.0 3 0 0 3 3 3 0 Autophagy protein Apg6 DMPK_coil PF08826.5 EIE89306.1 - 0.21 11.4 13.1 0.12 12.3 0.3 3.7 3 0 0 3 3 3 0 DMPK coiled coil domain like Selenoprotein_S PF06936.6 EIE89306.1 - 2.7 7.4 11.5 0.17 11.4 1.9 2.6 2 0 0 2 2 2 0 Selenoprotein S (SelS) TBPIP PF07106.8 EIE89306.1 - 3.6 7.1 18.3 0.21 11.0 5.0 2.9 3 0 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Gln-synt_C PF00120.19 EIE89307.1 - 8.2e-63 211.9 0.0 9.9e-63 211.6 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 EIE89307.1 - 5.7e-18 64.2 0.0 9.2e-18 63.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain PIP5K PF01504.13 EIE89308.1 - 2.3e-22 79.3 0.3 1.1e-16 60.7 0.0 2.0 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 EIE89309.1 - 1.3e-23 83.4 0.1 2.2e-23 82.6 0.1 1.3 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cyt-b5 PF00173.23 EIE89311.1 - 1.1e-11 44.3 0.0 1.3e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DEAD PF00270.24 EIE89312.1 - 1.8e-40 138.1 0.0 4.2e-40 136.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIE89312.1 - 3.1e-25 87.8 0.0 4e-24 84.2 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EIE89312.1 - 0.00048 19.0 0.0 0.00048 19.0 0.0 2.4 3 0 0 3 3 3 1 SNF2 family N-terminal domain Helicase_C_2 PF13307.1 EIE89312.1 - 0.043 13.7 0.9 0.15 11.9 0.0 2.2 2 0 0 2 2 2 0 Helicase C-terminal domain AAA_22 PF13401.1 EIE89312.1 - 0.071 13.2 4.2 0.099 12.7 0.4 3.0 2 2 0 2 2 2 0 AAA domain PLRV_ORF5 PF01690.12 EIE89312.1 - 2.7 7.0 26.3 0.28 10.2 14.1 2.1 2 0 0 2 2 2 0 Potato leaf roll virus readthrough protein Calreticulin PF00262.13 EIE89313.1 - 1.8e-107 359.1 14.1 1.8e-107 359.1 9.8 2.0 2 0 0 2 2 2 1 Calreticulin family SpaB_C PF14028.1 EIE89313.1 - 0.064 12.7 1.3 0.13 11.7 0.9 1.4 1 0 0 1 1 1 0 SpaB C-terminal domain DEAD PF00270.24 EIE89314.1 - 2.9e-39 134.2 0.0 9.3e-39 132.6 0.0 1.8 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIE89314.1 - 1.2e-25 89.1 1.2 5.1e-23 80.7 0.3 3.1 3 0 0 3 3 3 2 Helicase conserved C-terminal domain CMS1 PF14617.1 EIE89314.1 - 0.0014 17.7 0.0 0.0039 16.3 0.0 1.7 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit FXR1P_C PF12235.3 EIE89314.1 - 0.017 15.2 7.7 0.017 15.2 5.3 1.8 2 0 0 2 2 2 0 Fragile X-related 1 protein C terminal CNH PF00780.17 EIE89315.1 - 1.1e-05 24.9 0.1 0.043 13.2 0.0 2.2 2 0 0 2 2 2 2 CNH domain Lactamase_B PF00753.22 EIE89316.1 - 2e-16 60.2 0.9 3.6e-16 59.4 0.6 1.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EIE89316.1 - 3.2e-07 30.0 0.3 4.4e-07 29.6 0.2 1.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EIE89316.1 - 0.0008 19.1 0.0 0.0012 18.5 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain FUSC_2 PF13515.1 EIE89317.1 - 1.7e-21 76.4 11.2 1.7e-21 76.4 7.8 2.1 2 0 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.3 EIE89317.1 - 1.3e-14 53.7 3.5 1.7e-14 53.3 0.2 2.2 2 0 0 2 2 2 1 Aluminium activated malate transporter FUSC PF04632.7 EIE89317.1 - 3e-13 49.1 6.4 3e-13 49.1 4.4 2.0 2 0 0 2 2 2 1 Fusaric acid resistance protein family DUF2421 PF10334.4 EIE89317.1 - 3.7e-12 46.3 0.2 9.9e-12 44.9 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) DUF939 PF06081.6 EIE89317.1 - 0.00082 19.2 4.0 0.0031 17.3 2.8 2.0 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF939) MARVEL PF01284.18 EIE89317.1 - 0.51 10.1 18.0 0.04 13.7 1.7 3.5 2 1 0 2 2 2 0 Membrane-associating domain SHR3_chaperone PF08229.6 EIE89318.1 - 1.7e-21 76.0 2.6 1.9e-21 75.9 1.8 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 DUF2393 PF09624.5 EIE89318.1 - 0.12 11.8 1.4 0.25 10.8 0.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2393) Aa_trans PF01490.13 EIE89319.1 - 5.5e-32 110.7 17.6 7.2e-32 110.3 12.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Peptidase_S10 PF00450.17 EIE89320.1 - 6e-12 45.4 5.1 1.3e-09 37.7 0.6 2.0 1 1 1 2 2 2 2 Serine carboxypeptidase SET PF00856.23 EIE89321.1 - 4.7e-05 23.7 1.1 0.002 18.4 0.8 2.8 1 1 0 1 1 1 1 SET domain SUR7 PF06687.7 EIE89322.1 - 3e-16 59.6 16.6 3.8e-16 59.3 11.5 1.1 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.3 EIE89322.1 - 0.11 12.3 9.3 0.18 11.7 6.4 1.3 1 0 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 PIG-P PF08510.7 EIE89322.1 - 4.4 6.9 8.8 8.6 6.0 6.1 1.5 1 0 0 1 1 1 0 PIG-P Ribonuc_red_lgC PF02867.10 EIE89323.1 - 5.4e-176 586.3 0.0 7.3e-176 585.8 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 EIE89323.1 - 4.2e-18 64.9 0.2 1.3e-17 63.3 0.0 1.9 2 0 0 2 2 2 1 Ribonucleotide reductase, all-alpha domain PALP PF00291.20 EIE89324.1 - 3.7e-14 52.6 0.2 5.3e-14 52.1 0.2 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme FtsZ_C PF12327.3 EIE89324.1 - 0.064 13.3 0.1 0.62 10.1 0.0 2.2 2 1 0 2 2 2 0 FtsZ family, C-terminal domain TMEM154 PF15102.1 EIE89325.1 - 3.5e-05 23.5 0.4 6.8e-05 22.6 0.2 1.4 1 0 0 1 1 1 1 TMEM154 protein family EphA2_TM PF14575.1 EIE89325.1 - 0.02 15.2 0.0 0.075 13.4 0.0 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF106 PF01956.11 EIE89325.1 - 0.071 12.6 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Integral membrane protein DUF106 GNVR PF13807.1 EIE89325.1 - 0.098 12.4 0.1 0.21 11.3 0.1 1.5 1 0 0 1 1 1 0 G-rich domain on putative tyrosine kinase DUF1980 PF09323.5 EIE89325.1 - 0.45 10.2 7.1 3.6 7.2 0.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF1980) Gti1_Pac2 PF09729.4 EIE89325.1 - 3.1 7.6 7.6 0.37 10.6 1.7 2.1 2 1 0 2 2 2 0 Gti1/Pac2 family PP2C PF00481.16 EIE89326.1 - 8.6e-12 44.9 0.0 1.8e-05 24.2 0.0 2.1 1 1 1 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.7 EIE89326.1 - 1.5e-07 31.3 0.0 6e-06 26.0 0.0 2.1 1 1 1 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 EIE89326.1 - 0.0015 18.0 0.1 1.3 8.3 0.0 2.3 1 1 1 2 2 2 2 Protein phosphatase 2C Oxidored_q6 PF01058.17 EIE89329.1 - 1.2e-06 28.1 0.4 1.4e-06 27.9 0.3 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit SAC3_GANP PF03399.11 EIE89334.1 - 2.4e-54 184.0 2.8 4.4e-54 183.1 1.9 1.4 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Pro_CA PF00484.14 EIE89334.1 - 0.07 13.1 0.1 0.18 11.7 0.1 1.7 1 0 0 1 1 1 0 Carbonic anhydrase Cyt-b5 PF00173.23 EIE89336.1 - 2.5e-23 81.6 0.1 4.7e-23 80.7 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ATP_synt_I PF03899.10 EIE89336.1 - 0.026 14.6 0.2 0.057 13.5 0.1 1.5 1 0 0 1 1 1 0 ATP synthase I chain DUF1614 PF07758.6 EIE89336.1 - 0.042 13.5 0.2 0.067 12.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1614) Hema_stalk PF08720.5 EIE89338.1 - 0.13 11.7 1.4 0.25 10.8 1.0 1.4 1 0 0 1 1 1 0 Influenza C hemagglutinin stalk DUF4279 PF14106.1 EIE89338.1 - 0.67 9.8 4.4 1.4 8.7 0.1 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4279) HAP1_N PF04849.8 EIE89338.1 - 2 7.3 40.9 4.9 6.0 28.0 1.8 1 1 1 2 2 2 0 HAP1 N-terminal conserved region Matrilin_ccoil PF10393.4 EIE89338.1 - 4.2 6.8 10.7 5 6.5 1.3 3.2 3 0 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin Tcp11 PF05794.8 EIE89339.1 - 7.1e-61 206.2 7.7 1.5e-60 205.2 5.4 1.5 1 0 0 1 1 1 1 T-complex protein 11 DUF4137 PF13593.1 EIE89340.1 - 1.1e-82 277.6 18.2 1.3e-82 277.3 12.6 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.11 EIE89340.1 - 1.8e-06 27.4 9.4 1.8e-06 27.4 6.5 2.0 2 1 0 2 2 2 1 Sodium Bile acid symporter family DUF1451 PF07295.6 EIE89342.1 - 0.0021 17.8 11.4 0.33 10.7 0.8 4.1 3 2 1 4 4 4 3 Protein of unknown function (DUF1451) FKBP_N PF01346.13 EIE89342.1 - 0.0031 17.5 3.6 0.18 11.8 0.1 3.3 2 1 1 3 3 3 1 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase FliG_N PF14842.1 EIE89342.1 - 0.13 12.3 4.1 1.4 9.0 0.3 3.7 3 2 1 4 4 4 0 FliG N-terminal domain DUF1767 PF08585.7 EIE89342.1 - 0.21 11.8 1.7 1 9.6 0.5 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF1767) RhoGAP PF00620.22 EIE89342.1 - 0.45 10.1 2.9 1.6 8.3 0.0 2.9 2 1 0 2 2 2 0 RhoGAP domain Ish1 PF10281.4 EIE89342.1 - 0.79 9.8 11.3 0.61 10.2 0.3 4.5 4 0 0 4 4 4 0 Putative stress-responsive nuclear envelope protein ParB PF08775.5 EIE89342.1 - 6.5 7.0 15.5 4 7.7 0.1 4.5 3 2 3 6 6 6 0 ParB family DUF1002 PF06207.6 EIE89342.1 - 6.8 5.9 9.5 7 5.8 0.1 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF1002) DEAD PF00270.24 EIE89343.1 - 8.8e-42 142.4 0.0 8.8e-41 139.1 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIE89343.1 - 3.1e-26 91.0 0.1 9.4e-26 89.4 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PH_9 PF15410.1 EIE89345.1 - 1.7e-33 115.2 4.3 1.9e-33 115.1 0.9 2.4 2 1 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 EIE89345.1 - 2.6e-07 30.7 1.0 6.1e-07 29.6 0.1 2.1 2 0 0 2 2 2 1 PH domain PH_9 PF15410.1 EIE89346.1 - 1.9e-33 115.1 4.3 2.1e-33 114.9 0.9 2.4 2 1 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 EIE89346.1 - 2.4e-07 30.8 0.9 6.8e-07 29.4 0.1 2.1 2 0 0 2 2 2 1 PH domain OPT PF03169.10 EIE89347.1 - 4.8e-150 500.9 42.5 6e-150 500.6 29.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Poty_PP PF08440.5 EIE89350.1 - 0.0029 16.7 1.6 0.0043 16.1 1.1 1.2 1 0 0 1 1 1 1 Potyviridae polyprotein AIP3 PF03915.8 EIE89350.1 - 0.014 14.3 2.5 0.02 13.8 1.8 1.2 1 0 0 1 1 1 0 Actin interacting protein 3 ATP-synt_B PF00430.13 EIE89350.1 - 1.4 8.7 8.1 0.67 9.7 3.8 1.8 2 1 0 2 2 2 0 ATP synthase B/B' CF(0) Nucleotid_trans PF03407.11 EIE89351.1 - 1.3e-26 93.7 0.2 1.6e-26 93.4 0.2 1.1 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase PNK3P PF08645.6 EIE89353.1 - 5.2e-57 191.7 0.5 1.2e-56 190.5 0.0 1.8 2 0 0 2 2 2 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.1 EIE89353.1 - 4.7e-23 81.6 0.0 2.2e-22 79.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EIE89353.1 - 1.7e-07 30.5 0.0 0.019 14.0 0.0 2.9 3 0 0 3 3 3 2 Zeta toxin KTI12 PF08433.5 EIE89353.1 - 5e-05 22.6 4.4 0.0074 15.5 1.0 2.3 1 1 1 2 2 2 2 Chromatin associated protein KTI12 HAD_2 PF13419.1 EIE89353.1 - 0.0021 18.2 0.1 0.094 12.9 0.0 2.4 1 1 1 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EIE89353.1 - 0.0057 16.5 0.0 0.02 14.7 0.0 1.9 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase NIF PF03031.13 EIE89353.1 - 0.014 15.0 0.1 0.045 13.4 0.0 1.9 2 0 0 2 2 2 0 NLI interacting factor-like phosphatase AAA_17 PF13207.1 EIE89353.1 - 0.03 15.1 0.0 0.17 12.6 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EIE89353.1 - 0.037 13.9 0.0 0.076 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain zf-CCCH PF00642.19 EIE89354.1 - 0.0022 17.6 0.5 0.0035 16.9 0.0 1.6 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) tRNA_anti-codon PF01336.20 EIE89354.1 - 0.094 12.5 0.1 0.43 10.4 0.0 2.1 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain Methyltransf_23 PF13489.1 EIE89354.1 - 0.13 12.0 0.0 0.51 10.0 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain zf-CCCH_2 PF14608.1 EIE89354.1 - 0.25 11.3 3.0 0.91 9.6 2.1 2.0 1 1 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type MoCF_biosynth PF00994.19 EIE89355.1 - 6.1e-30 103.5 0.0 9.6e-30 102.8 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain Transket_pyr PF02779.19 EIE89358.1 - 3.6e-63 212.2 0.0 5.7e-63 211.6 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 EIE89358.1 - 1.1e-60 204.9 0.0 1.4e-60 204.5 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component UQ_con PF00179.21 EIE89359.1 - 2.8e-44 149.9 0.2 3.1e-44 149.7 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme PAH PF02671.16 EIE89361.1 - 9.7e-45 149.9 4.3 1.2e-16 60.0 0.3 4.0 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 EIE89361.1 - 1.6e-36 124.0 0.5 1.6e-36 124.0 0.4 2.2 2 0 0 2 2 2 1 Sin3 family co-repressor TRAP_alpha PF03896.11 EIE89361.1 - 0.22 10.5 10.8 0.51 9.2 7.5 1.6 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Trypan_PARP PF05887.6 EIE89361.1 - 8.6 6.1 13.5 20 4.9 9.3 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) EMG1 PF03587.9 EIE89362.1 - 6.3e-76 254.1 0.1 7.9e-76 253.8 0.1 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Pardaxin PF07425.6 EIE89363.1 - 0.88 9.0 3.7 0.48 9.8 0.2 2.2 2 0 0 2 2 2 0 Pardaxin SUI1 PF01253.17 EIE89365.1 - 2e-20 72.3 0.0 3.6e-20 71.5 0.0 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 LIM PF00412.17 EIE89366.1 - 3e-20 72.0 7.2 3.3e-10 39.8 2.3 2.3 2 0 0 2 2 2 2 LIM domain GlcNAc PF11397.3 EIE89366.1 - 0.061 12.4 0.1 0.092 11.8 0.1 1.3 1 0 0 1 1 1 0 Glycosyltransferase (GlcNAc) ATPase-cat_bd PF12156.3 EIE89366.1 - 0.11 13.0 4.4 6.2 7.4 0.1 2.3 2 0 0 2 2 2 0 Putative metal-binding domain of cation transport ATPase Fer4_21 PF14697.1 EIE89366.1 - 0.35 10.7 3.4 0.29 11.0 0.4 2.1 2 0 0 2 2 2 0 4Fe-4S dicluster domain DUF1364 PF07102.7 EIE89366.1 - 4.6 7.1 6.9 14 5.6 0.1 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF1364) CK_II_beta PF01214.13 EIE89367.1 - 9.6e-77 256.6 0.1 1.1e-76 256.3 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit HlyIII PF03006.15 EIE89368.1 - 4e-18 65.6 5.3 4.6e-18 65.4 3.7 1.0 1 0 0 1 1 1 1 Haemolysin-III related FMN_red PF03358.10 EIE89369.1 - 2.1e-13 50.0 0.0 3.1e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 EIE89369.1 - 3.2e-09 36.6 0.0 4.1e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_4 PF12682.2 EIE89369.1 - 0.023 14.0 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 Flavodoxin G-patch PF01585.18 EIE89370.1 - 2.6e-15 55.9 1.6 3.6e-15 55.4 1.1 1.2 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EIE89370.1 - 4.7e-07 29.5 0.0 7.4e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 DExH-box splicing factor binding site SPRY PF00622.23 EIE89370.1 - 0.072 13.1 0.0 0.095 12.7 0.0 1.2 1 0 0 1 1 1 0 SPRY domain Rrp15p PF07890.7 EIE89371.1 - 7.1e-32 110.1 7.1 7.1e-32 110.1 4.9 1.9 2 1 0 2 2 2 1 Rrp15p TPT PF03151.11 EIE89371.1 - 8.9e-29 100.1 15.8 8.9e-29 100.1 11.0 2.1 2 0 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EIE89371.1 - 1.9e-05 24.7 29.6 0.0073 16.3 3.0 2.5 2 1 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 EIE89371.1 - 0.00092 19.3 0.7 0.00092 19.3 0.5 3.2 2 1 1 3 3 3 1 Multidrug resistance efflux transporter LcrR PF09621.5 EIE89371.1 - 0.02 14.1 0.0 0.039 13.2 0.0 1.4 1 0 0 1 1 1 0 Type III secretion system regulator (LcrR) UAA PF08449.6 EIE89371.1 - 0.073 11.9 19.8 0.29 10.0 13.7 1.9 1 1 0 1 1 1 0 UAA transporter family Astro_capsid PF03115.9 EIE89371.1 - 0.085 11.1 9.9 0.14 10.3 6.8 1.3 1 0 0 1 1 1 0 Astrovirus capsid protein precursor TT_ORF2 PF02957.10 EIE89371.1 - 3.5 8.3 7.9 0.74 10.5 3.1 1.6 2 0 0 2 2 2 0 TT viral ORF2 CDC45 PF02724.9 EIE89371.1 - 8.9 4.2 16.0 12 3.7 11.1 1.1 1 0 0 1 1 1 0 CDC45-like protein LRR_8 PF13855.1 EIE89373.1 - 7.2e-35 118.5 31.1 8e-14 51.1 2.0 7.3 3 1 4 8 8 8 7 Leucine rich repeat LRR_4 PF12799.2 EIE89373.1 - 5e-32 108.9 32.5 3e-07 29.8 3.5 8.2 6 2 1 8 8 8 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EIE89373.1 - 2.1e-22 75.6 36.3 0.052 13.5 0.4 14.3 16 0 0 16 16 16 7 Leucine Rich Repeat LRR_7 PF13504.1 EIE89373.1 - 2.7e-12 44.7 30.1 1.1 9.7 0.1 12.5 13 0 0 13 13 13 5 Leucine rich repeat LRR_6 PF13516.1 EIE89373.1 - 4.2e-06 26.2 24.0 0.45 10.7 0.4 9.5 11 0 0 11 11 11 3 Leucine Rich repeat LRR_9 PF14580.1 EIE89373.1 - 2.1e-05 24.1 1.7 0.074 12.6 0.0 2.8 2 1 1 3 3 3 2 Leucine-rich repeat LRR_5 PF13306.1 EIE89373.1 - 5.9e-05 22.7 2.6 0.00058 19.5 0.1 3.1 3 0 0 3 3 3 1 Leucine rich repeats (6 copies) Peptidase_M18 PF02127.10 EIE89375.1 - 2.2e-07 29.7 0.1 2.5e-07 29.5 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) DnaJ PF00226.26 EIE89375.1 - 0.0094 15.6 0.0 0.012 15.3 0.0 1.2 1 0 0 1 1 1 1 DnaJ domain MFS_1 PF07690.11 EIE89376.1 - 5.6e-13 48.3 27.5 7.7e-13 47.8 19.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 EIE89376.1 - 1.5e-11 44.0 3.7 1.5e-11 44.0 2.6 2.4 2 1 0 2 2 2 1 Ion channel regulatory protein UNC-93 DDE_Tnp_1_assoc PF13808.1 EIE89378.1 - 0.034 13.8 0.1 0.22 11.2 0.0 1.9 2 0 0 2 2 2 0 DDE_Tnp_1-associated WRKY PF03106.10 EIE89379.1 - 0.31 10.9 2.1 0.64 9.8 1.4 1.5 1 0 0 1 1 1 0 WRKY DNA -binding domain Pex14_N PF04695.8 EIE89379.1 - 0.55 10.2 4.9 13 5.8 0.0 2.9 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region P53_TAD PF08563.6 EIE89379.1 - 0.84 8.7 4.4 6.8 5.8 0.2 2.7 2 0 0 2 2 2 0 P53 transactivation motif PAS_3 PF08447.6 EIE89380.1 - 1.5e-13 50.6 0.0 3.4e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS PF00989.19 EIE89380.1 - 3.6e-10 39.6 0.0 2.8e-09 36.7 0.0 2.0 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.5 EIE89380.1 - 3.4e-09 36.7 0.0 6.6e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.1 EIE89380.1 - 6.6e-08 32.8 0.0 1.5e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS_11 PF14598.1 EIE89380.1 - 7.5e-08 32.3 0.0 1.5e-07 31.3 0.0 1.5 1 1 0 1 1 1 1 PAS domain PAS_2 PF08446.6 EIE89380.1 - 0.0041 17.5 0.0 0.0091 16.4 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.1 EIE89380.1 - 0.076 12.9 0.0 0.98 9.3 0.0 2.5 2 0 0 2 2 2 0 PAS domain ATP_bind_1 PF03029.12 EIE89381.1 - 5.2e-84 281.5 0.4 6.1e-84 281.2 0.3 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 EIE89381.1 - 7.4e-07 28.7 0.6 1e-05 25.0 0.4 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_10 PF12846.2 EIE89381.1 - 3.2e-05 23.5 0.0 4.5e-05 23.0 0.0 1.4 1 1 0 1 1 1 1 AAA-like domain AAA_22 PF13401.1 EIE89381.1 - 5.2e-05 23.4 0.0 0.00015 21.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain cobW PF02492.14 EIE89381.1 - 7.5e-05 22.2 0.0 0.36 10.2 0.0 2.5 2 1 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain G-alpha PF00503.15 EIE89381.1 - 8.6e-05 21.3 0.0 0.025 13.2 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit AAA_33 PF13671.1 EIE89381.1 - 0.00025 20.9 0.0 0.00048 20.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 EIE89381.1 - 0.00026 20.9 0.0 0.00047 20.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EIE89381.1 - 0.00039 19.7 0.0 0.0066 15.7 0.0 2.5 3 0 0 3 3 3 1 Ferrous iron transport protein B AAA_16 PF13191.1 EIE89381.1 - 0.00051 20.0 0.0 0.00093 19.2 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.17 EIE89381.1 - 0.0011 17.8 0.2 0.0056 15.5 0.0 2.0 3 0 0 3 3 3 1 NB-ARC domain NACHT PF05729.7 EIE89381.1 - 0.0018 17.9 0.0 0.0031 17.1 0.0 1.4 1 0 0 1 1 1 1 NACHT domain SRP54 PF00448.17 EIE89381.1 - 0.0019 17.7 0.0 0.018 14.4 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain MobB PF03205.9 EIE89381.1 - 0.0035 17.0 0.0 0.0062 16.2 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 EIE89381.1 - 0.0037 18.0 0.0 0.0081 16.9 0.0 1.7 2 0 0 2 2 1 1 AAA domain PduV-EutP PF10662.4 EIE89381.1 - 0.0064 15.9 0.1 0.071 12.5 0.0 2.5 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation ArgK PF03308.11 EIE89381.1 - 0.01 14.6 0.0 1.1 7.9 0.0 2.2 2 0 0 2 2 2 0 ArgK protein Arf PF00025.16 EIE89381.1 - 0.011 14.9 0.0 0.39 9.9 0.0 2.7 2 1 0 2 2 2 0 ADP-ribosylation factor family UPF0079 PF02367.12 EIE89381.1 - 0.013 15.1 0.0 0.072 12.7 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 EIE89381.1 - 0.013 15.1 0.0 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EIE89381.1 - 0.026 14.2 0.0 0.1 12.2 0.0 2.0 2 1 0 2 2 2 0 Archaeal ATPase Zeta_toxin PF06414.7 EIE89381.1 - 0.027 13.5 0.0 0.048 12.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Glyco_tranf_2_3 PF13641.1 EIE89381.1 - 0.034 13.9 0.0 0.045 13.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 FtsK_SpoIIIE PF01580.13 EIE89381.1 - 0.041 13.3 0.0 0.065 12.7 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family PRK PF00485.13 EIE89381.1 - 0.044 13.3 0.0 0.1 12.1 0.0 1.7 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family SRPRB PF09439.5 EIE89381.1 - 0.048 12.8 0.0 1.4 8.1 0.0 2.2 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit APS_kinase PF01583.15 EIE89381.1 - 0.057 13.0 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_19 PF13245.1 EIE89381.1 - 0.064 13.0 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain AAA_14 PF13173.1 EIE89381.1 - 0.081 12.8 0.0 0.57 10.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.12 EIE89381.1 - 0.093 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Thymidylate kinase KTI12 PF08433.5 EIE89381.1 - 0.12 11.5 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Skp1 PF01466.14 EIE89382.1 - 7.1e-39 131.7 2.2 7.1e-39 131.7 1.5 1.5 2 0 0 2 2 2 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 EIE89382.1 - 6.1e-27 93.4 0.6 2e-26 91.8 0.1 2.0 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain BTB PF00651.26 EIE89382.1 - 0.068 13.1 0.0 0.82 9.6 0.0 2.1 1 1 0 1 1 1 0 BTB/POZ domain DUF4375 PF14300.1 EIE89382.1 - 0.58 10.1 3.8 0.41 10.6 0.2 2.2 2 1 0 3 3 3 0 Domain of unknown function (DUF4375) Ribosomal_L9_N PF01281.14 EIE89383.1 - 0.04 13.1 0.0 0.06 12.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L9, N-terminal domain MukE PF04288.8 EIE89383.1 - 0.05 12.4 0.2 0.052 12.3 0.1 1.1 1 0 0 1 1 1 0 MukE-like family Abhydrolase_3 PF07859.8 EIE89385.1 - 9.1e-22 77.6 0.0 1.4e-21 77.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EIE89385.1 - 3.9e-19 68.7 0.2 1e-18 67.3 0.2 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 EIE89385.1 - 7.4e-08 32.2 0.2 1.1e-07 31.7 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EIE89385.1 - 1.8e-05 24.0 0.5 7.8e-05 21.9 0.3 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EIE89385.1 - 0.00029 20.7 0.3 0.00096 19.0 0.2 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EIE89385.1 - 0.011 15.1 0.3 0.11 11.9 0.0 2.6 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase UFD1 PF03152.9 EIE89386.1 - 1.1e-57 194.0 0.1 1.4e-46 157.8 0.0 2.1 1 1 1 2 2 2 2 Ubiquitin fusion degradation protein UFD1 HA2 PF04408.18 EIE89387.1 - 3.1e-20 72.0 0.0 1e-19 70.4 0.0 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EIE89387.1 - 2.4e-19 69.2 0.0 7.4e-19 67.6 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EIE89387.1 - 1.6e-13 50.2 0.0 8.6e-13 47.9 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EIE89387.1 - 9.1e-08 31.7 0.8 3.1e-07 30.0 0.6 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EIE89387.1 - 6.7e-07 29.5 0.0 2.7e-06 27.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 EIE89387.1 - 0.0021 17.0 0.0 0.0038 16.1 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein KaiC PF06745.8 EIE89387.1 - 0.0039 16.3 0.0 0.0083 15.2 0.0 1.6 1 0 0 1 1 1 1 KaiC ResIII PF04851.10 EIE89387.1 - 0.0043 16.8 2.3 0.29 10.9 0.0 3.6 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit FtsK_SpoIIIE PF01580.13 EIE89387.1 - 0.015 14.7 0.0 0.1 12.0 0.0 2.2 1 1 1 2 2 2 0 FtsK/SpoIIIE family AAA_33 PF13671.1 EIE89387.1 - 0.02 14.7 0.1 0.062 13.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 EIE89387.1 - 0.042 13.0 0.2 0.12 11.5 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein FERM_M PF00373.13 EIE89387.1 - 0.078 13.1 2.7 4.2 7.5 0.1 2.9 3 0 0 3 3 3 0 FERM central domain YL1 PF05764.8 EIE89387.1 - 0.12 11.9 24.1 0.16 11.5 0.0 3.5 3 0 0 3 3 3 0 YL1 nuclear protein RRM_1 PF00076.17 EIE89389.1 - 0.0001 21.8 0.1 0.01 15.4 0.0 3.0 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE89389.1 - 0.00024 21.0 0.0 0.0013 18.7 0.0 2.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE89389.1 - 0.00082 19.1 0.1 0.0054 16.5 0.1 2.3 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CDC45 PF02724.9 EIE89389.1 - 3.4 5.6 28.1 0.026 12.5 11.1 2.1 2 0 0 2 2 2 0 CDC45-like protein FAD_binding_1 PF00667.15 EIE89391.1 - 2.4e-07 30.4 0.0 2.5e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain BCAS3 PF12490.3 EIE89392.1 - 8.3e-10 38.3 3.8 9.9e-08 31.5 1.4 3.3 2 1 0 2 2 2 1 Breast carcinoma amplified sequence 3 WD40 PF00400.27 EIE89392.1 - 0.00017 21.3 0.6 0.00017 21.3 0.4 3.1 3 0 0 3 3 3 1 WD domain, G-beta repeat RrnaAD PF00398.15 EIE89393.1 - 4.7e-60 202.8 0.0 6.3e-60 202.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 EIE89393.1 - 2.8e-11 43.4 0.0 4.3e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIE89393.1 - 3.3e-05 24.4 0.0 5.4e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.7 EIE89393.1 - 0.0028 16.5 0.0 0.0048 15.7 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase PCMT PF01135.14 EIE89393.1 - 0.0029 17.1 0.0 0.0048 16.4 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 EIE89393.1 - 0.0031 16.9 0.0 0.007 15.7 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_12 PF08242.7 EIE89393.1 - 0.0043 17.4 0.0 0.0082 16.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIE89393.1 - 0.0044 16.7 0.0 0.0065 16.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_28 PF02636.12 EIE89393.1 - 0.0045 16.4 0.0 0.0068 15.8 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase CMAS PF02353.15 EIE89393.1 - 0.0094 15.0 0.0 0.023 13.7 0.0 1.5 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.13 EIE89393.1 - 0.016 14.4 0.0 0.026 13.7 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase NodS PF05401.6 EIE89393.1 - 0.04 13.3 0.0 0.068 12.5 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) PRMT5 PF05185.11 EIE89393.1 - 0.06 12.2 0.0 0.085 11.7 0.0 1.2 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Met_10 PF02475.11 EIE89393.1 - 0.073 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_25 PF13649.1 EIE89393.1 - 0.13 12.6 0.0 0.3 11.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain RVT_1 PF00078.22 EIE89394.1 - 1.6e-07 30.9 0.0 2.1e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Viral_env_E26 PF11050.3 EIE89397.1 - 0.018 14.2 0.1 0.021 14.0 0.0 1.0 1 0 0 1 1 1 0 Virus envelope protein E26 Ribosomal_L19e PF01280.15 EIE89397.1 - 0.076 12.7 0.2 0.092 12.5 0.2 1.1 1 0 0 1 1 1 0 Ribosomal protein L19e Ribosomal_L9_C PF03948.9 EIE89398.1 - 0.021 14.8 0.0 0.036 14.1 0.0 1.4 1 1 0 1 1 1 0 Ribosomal protein L9, C-terminal domain FAR1 PF03101.10 EIE89399.1 - 1.6e-05 25.3 0.2 3.2e-05 24.3 0.1 1.4 1 0 0 1 1 1 1 FAR1 DNA-binding domain TAF4 PF05236.9 EIE89400.1 - 1e-19 70.8 1.1 1e-19 70.8 0.8 1.7 2 0 0 2 2 2 1 Transcription initiation factor TFIID component TAF4 family DUF4078 PF13300.1 EIE89401.1 - 6.3e-22 77.4 4.5 6.3e-22 77.4 3.1 4.1 3 2 1 4 4 4 1 Domain of unknown function (DUF4078) GWT1 PF06423.7 EIE89402.1 - 1.4e-10 41.4 3.1 3.3e-10 40.1 0.1 2.7 2 1 0 2 2 2 1 GWT1 DUF3353 PF11833.3 EIE89402.1 - 0.16 11.3 3.8 0.54 9.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3353) Ribosomal_S25 PF03297.10 EIE89403.1 - 9.2e-42 141.3 2.4 9.9e-42 141.2 1.6 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_24 PF13412.1 EIE89403.1 - 0.0066 15.8 0.5 0.0097 15.2 0.3 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding BioT2 PF15368.1 EIE89403.1 - 0.026 14.2 0.2 0.026 14.2 0.2 1.2 1 0 0 1 1 1 0 Spermatogenesis family BioT2 MarR_2 PF12802.2 EIE89403.1 - 0.044 13.4 0.0 0.051 13.2 0.0 1.2 1 0 0 1 1 1 0 MarR family RNA_pol_Rpc34 PF05158.7 EIE89403.1 - 0.11 11.7 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase Rpc34 subunit Acyltransferase PF01553.16 EIE89404.1 - 2.1e-11 43.3 0.0 1.7e-10 40.4 0.0 2.2 1 1 0 1 1 1 1 Acyltransferase IIGP PF05049.8 EIE89405.1 - 2.1e-16 59.7 0.0 2.5e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) MMR_HSR1 PF01926.18 EIE89405.1 - 5.9e-07 29.4 0.0 8.1e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EIE89405.1 - 0.00016 20.8 0.0 0.00021 20.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 EIE89405.1 - 0.0052 17.2 0.0 0.0076 16.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein cobW PF02492.14 EIE89405.1 - 0.0059 16.0 0.1 0.0091 15.4 0.0 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.18 EIE89405.1 - 0.008 16.0 0.2 0.035 13.9 0.2 1.8 2 0 0 2 2 2 1 Dynamin family AIG1 PF04548.11 EIE89405.1 - 0.011 14.8 0.0 0.013 14.5 0.0 1.2 1 0 0 1 1 1 0 AIG1 family FtsK_SpoIIIE PF01580.13 EIE89405.1 - 0.02 14.3 0.0 0.027 13.9 0.0 1.1 1 0 0 1 1 1 0 FtsK/SpoIIIE family FeoB_N PF02421.13 EIE89405.1 - 0.025 13.8 0.0 0.036 13.3 0.0 1.2 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_32 PF13654.1 EIE89405.1 - 0.039 12.6 0.0 0.05 12.2 0.0 1.1 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EIE89405.1 - 0.04 14.2 0.0 0.057 13.7 0.0 1.2 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 EIE89405.1 - 0.082 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 EIE89405.1 - 0.084 12.8 0.0 0.097 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain DUF815 PF05673.8 EIE89405.1 - 0.11 11.3 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Vac_ImportDeg PF09783.4 EIE89406.1 - 9e-32 109.9 5.0 9.9e-32 109.8 3.5 1.0 1 0 0 1 1 1 1 Vacuolar import and degradation protein DUF2138 PF09909.4 EIE89406.1 - 0.1 10.7 0.2 0.11 10.6 0.1 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2138) LRR_4 PF12799.2 EIE89407.1 - 0.028 14.0 0.4 3.7 7.2 0.1 2.9 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) Sec20 PF03908.8 EIE89408.1 - 0.03 14.0 0.1 0.44 10.2 0.0 2.4 2 1 0 2 2 2 0 Sec20 Not3 PF04065.10 EIE89409.1 - 0.016 14.5 0.5 0.016 14.5 0.3 1.1 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component Response_reg PF00072.19 EIE89410.1 - 1e-16 60.9 0.0 1.4e-16 60.4 0.0 1.1 1 0 0 1 1 1 1 Response regulator receiver domain Biotin_carb_C PF02785.14 EIE89411.1 - 0.075 13.0 0.1 0.11 12.5 0.0 1.4 1 1 0 1 1 1 0 Biotin carboxylase C-terminal domain Phage_C PF12025.3 EIE89412.1 - 0.032 14.1 0.1 0.071 13.0 0.0 1.6 2 0 0 2 2 2 0 Phage protein C YABBY PF04690.8 EIE89413.1 - 3.4e-05 24.1 0.4 3.7e-05 24.0 0.3 1.1 1 0 0 1 1 1 1 YABBY protein DUF1014 PF06244.7 EIE89413.1 - 0.0031 17.7 6.2 0.0043 17.2 4.3 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1014) HMG_box PF00505.14 EIE89413.1 - 0.02 15.1 1.9 0.044 14.0 1.2 1.7 1 1 0 1 1 1 0 HMG (high mobility group) box PTH2 PF01981.11 EIE89414.1 - 7.8e-08 32.0 0.1 1e-07 31.6 0.1 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 TRM PF02005.11 EIE89415.1 - 2.9e-133 444.4 0.1 3.7e-133 444.1 0.1 1.0 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase MTS PF05175.9 EIE89415.1 - 0.00028 20.3 0.0 0.00054 19.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.11 EIE89415.1 - 0.0022 17.6 0.1 0.0044 16.6 0.1 1.5 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.10 EIE89415.1 - 0.0038 16.6 0.0 0.0071 15.7 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical protein 95 SSFA2_C PF14723.1 EIE89415.1 - 0.058 13.1 0.1 0.43 10.2 0.0 2.3 3 0 0 3 3 3 0 Sperm-specific antigen 2 C-terminus Methyltransf_26 PF13659.1 EIE89415.1 - 0.082 12.9 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF1492 PF07374.6 EIE89415.1 - 0.45 10.6 3.2 2.1 8.4 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1492) PX PF00787.19 EIE89416.1 - 3e-27 94.6 0.0 3.5e-27 94.4 0.0 1.1 1 0 0 1 1 1 1 PX domain SET PF00856.23 EIE89418.1 - 4.2e-09 36.9 0.1 1.8e-08 34.8 0.1 2.0 2 0 0 2 2 2 1 SET domain FeoC PF09012.5 EIE89419.1 - 0.12 12.1 1.1 0.22 11.2 0.0 1.8 2 0 0 2 2 2 0 FeoC like transcriptional regulator Y_phosphatase3 PF13350.1 EIE89421.1 - 7.6e-18 65.2 0.0 1.3e-17 64.5 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 EIE89421.1 - 9.6e-10 38.4 0.2 1.7e-09 37.6 0.1 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Y_phosphatase2 PF03162.8 EIE89421.1 - 1.9e-06 27.3 0.0 2.4e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 EIE89421.1 - 0.12 11.6 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Plant_tran PF04827.9 EIE89423.1 - 2.8e-57 193.4 0.2 3.7e-57 193.0 0.1 1.1 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_4 PF13359.1 EIE89423.1 - 0.02 14.4 0.0 0.027 14.0 0.0 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease DUF3582 PF12122.3 EIE89424.1 - 0.029 14.3 0.0 0.078 12.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3582) Aminotran_1_2 PF00155.16 EIE89426.1 - 4e-40 137.8 0.0 5.2e-40 137.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EIE89426.1 - 0.00074 18.7 0.0 0.0016 17.6 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase zf-C5HC2 PF02928.11 EIE89428.1 - 0.00077 19.4 10.4 0.19 11.7 0.5 2.4 2 0 0 2 2 2 2 C5HC2 zinc finger BT1 PF03092.11 EIE89428.1 - 0.31 9.6 5.6 0.42 9.2 3.9 1.2 1 0 0 1 1 1 0 BT1 family DUF515 PF04415.7 EIE89428.1 - 0.76 7.9 14.1 1.1 7.4 9.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) EGF_3 PF12947.2 EIE89428.1 - 2.5 8.1 15.7 0.24 11.3 2.7 2.7 2 0 0 2 2 2 0 EGF domain Glycohydro_20b2 PF14845.1 EIE89429.1 - 1.2 9.7 5.6 2.5 8.7 3.9 1.4 1 1 0 1 1 1 0 beta-acetyl hexosaminidase like Rho_GDI PF02115.12 EIE89430.1 - 1.4e-65 220.4 1.1 1.5e-65 220.3 0.8 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Ribosomal_S4 PF00163.14 EIE89431.1 - 1.5e-12 47.6 2.4 2.7e-12 46.8 1.6 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 EIE89431.1 - 2.2e-11 43.0 0.0 4e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 S4 domain Peptidase_S76 PF13611.1 EIE89431.1 - 0.14 12.2 0.7 0.22 11.6 0.3 1.5 1 1 0 1 1 1 0 Serine peptidase of plant viral polyprotein, P1 UvdE PF03851.9 EIE89432.1 - 1.2e-62 211.4 0.2 1.9e-35 122.2 0.1 2.3 2 0 0 2 2 2 2 UV-endonuclease UvdE Acyl_transf_1 PF00698.16 EIE89432.1 - 2.8e-26 92.6 0.1 7.6e-26 91.1 0.1 1.7 1 0 0 1 1 1 1 Acyl transferase domain AAA PF00004.24 EIE89433.1 - 2.3e-62 209.0 0.4 7.1e-37 126.5 0.0 3.5 2 1 1 3 3 3 3 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EIE89433.1 - 2.2e-09 37.1 0.3 5e-05 23.0 0.0 3.6 3 2 1 4 4 4 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EIE89433.1 - 6.8e-09 35.9 0.5 0.0026 17.7 0.1 3.2 2 1 0 2 2 2 2 AAA ATPase domain RuvB_N PF05496.7 EIE89433.1 - 3e-07 29.7 0.0 0.013 14.5 0.0 3.5 5 0 0 5 5 4 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EIE89433.1 - 4.2e-07 30.1 0.0 0.0085 16.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EIE89433.1 - 3.6e-06 26.9 0.0 0.00052 19.9 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EIE89433.1 - 5.3e-06 27.2 0.0 0.00039 21.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EIE89433.1 - 5.5e-06 26.2 0.0 0.26 10.9 0.0 3.2 2 1 0 2 2 2 2 Archaeal ATPase RNA_helicase PF00910.17 EIE89433.1 - 7.4e-06 26.0 0.0 0.0098 16.0 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_24 PF13479.1 EIE89433.1 - 9.5e-06 25.3 1.0 0.035 13.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 EIE89433.1 - 8.5e-05 22.4 0.0 0.38 10.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 EIE89433.1 - 0.0001 21.8 0.1 0.0056 16.1 0.0 2.6 3 0 0 3 3 2 1 IstB-like ATP binding protein AAA_25 PF13481.1 EIE89433.1 - 0.00018 21.0 0.1 0.0091 15.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EIE89433.1 - 0.00054 19.6 0.9 0.57 9.9 0.0 3.2 3 0 0 3 3 3 1 Part of AAA domain Zeta_toxin PF06414.7 EIE89433.1 - 0.0006 18.9 0.0 0.3 10.1 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin Rad17 PF03215.10 EIE89433.1 - 0.00062 18.5 0.1 0.05 12.2 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_3 PF07726.6 EIE89433.1 - 0.0011 18.6 0.0 0.11 12.1 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 EIE89433.1 - 0.0011 18.6 0.0 0.1 12.3 0.0 3.0 3 0 0 3 3 3 1 NTPase DUF815 PF05673.8 EIE89433.1 - 0.0012 17.8 0.0 0.25 10.2 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_2 PF07724.9 EIE89433.1 - 0.0013 18.6 0.0 0.61 9.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_11 PF13086.1 EIE89433.1 - 0.0018 17.9 0.0 0.55 9.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EIE89433.1 - 0.0023 17.1 0.2 0.6 9.2 0.0 2.8 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_10 PF12846.2 EIE89433.1 - 0.0041 16.5 0.1 0.15 11.4 0.0 2.8 2 1 1 3 3 3 1 AAA-like domain cobW PF02492.14 EIE89433.1 - 0.0071 15.8 0.1 0.42 10.0 0.0 2.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.22 EIE89433.1 - 0.008 16.4 0.0 1.4 9.2 0.0 2.6 3 0 0 3 3 2 1 ABC transporter AAA_28 PF13521.1 EIE89433.1 - 0.0099 15.8 0.1 0.16 11.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 EIE89433.1 - 0.026 13.2 0.2 3.8 6.1 0.0 2.5 2 1 0 2 2 2 0 TIP49 C-terminus PIF1 PF05970.9 EIE89433.1 - 0.032 13.1 0.1 3.4 6.5 0.0 2.4 2 0 0 2 2 2 0 PIF1-like helicase NACHT PF05729.7 EIE89433.1 - 0.038 13.6 0.2 0.85 9.2 0.0 2.5 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.1 EIE89433.1 - 0.056 13.7 0.1 0.39 11.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain AFG1_ATPase PF03969.11 EIE89433.1 - 0.08 11.7 0.0 1.3 7.7 0.0 2.2 2 0 0 2 2 2 0 AFG1-like ATPase Bac_DnaA PF00308.13 EIE89433.1 - 0.086 12.4 0.1 8 6.0 0.0 3.5 4 0 0 4 4 4 0 Bacterial dnaA protein UPF0079 PF02367.12 EIE89433.1 - 0.1 12.2 0.0 3.4 7.3 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Molydop_binding PF01568.16 EIE89434.1 - 0.0019 17.9 0.0 0.0023 17.7 0.0 1.1 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain Med7 PF05983.6 EIE89435.1 - 4.6e-32 111.0 7.7 8.5e-22 77.6 1.2 2.0 1 1 1 2 2 2 2 MED7 protein AAA_11 PF13086.1 EIE89436.1 - 5.7e-61 206.0 2.0 5.3e-60 202.9 0.2 2.1 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 EIE89436.1 - 2.8e-57 193.3 1.1 5.6e-57 192.3 0.1 1.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EIE89436.1 - 9e-13 47.7 0.5 3.6e-12 45.8 0.1 2.1 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EIE89436.1 - 9.7e-13 48.1 0.0 6.8e-09 35.5 0.0 2.8 3 0 0 3 3 3 2 AAA domain Viral_helicase1 PF01443.13 EIE89436.1 - 1.2e-10 41.3 0.0 0.0016 18.0 0.0 3.3 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase ResIII PF04851.10 EIE89436.1 - 1.6e-07 31.3 0.0 6.7e-07 29.3 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 EIE89436.1 - 4.4e-07 29.1 2.0 0.0083 15.1 0.0 3.0 3 1 0 3 3 3 2 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 EIE89436.1 - 1e-05 25.6 1.3 0.00021 21.4 0.1 3.0 2 2 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EIE89436.1 - 5.8e-05 23.1 0.4 0.00021 21.3 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain Helicase_RecD PF05127.9 EIE89436.1 - 7.9e-05 22.3 0.1 0.0028 17.3 0.1 2.4 1 1 0 1 1 1 1 Helicase AAA_25 PF13481.1 EIE89436.1 - 9.2e-05 21.9 0.9 0.031 13.6 0.0 3.2 2 1 1 3 3 3 1 AAA domain UvrD-helicase PF00580.16 EIE89436.1 - 0.00015 21.2 0.2 0.00043 19.6 0.2 1.9 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain DEAD PF00270.24 EIE89436.1 - 0.00053 19.5 0.2 0.011 15.2 0.2 2.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase PhoH PF02562.11 EIE89436.1 - 0.0012 18.0 0.2 0.013 14.7 0.1 2.3 1 1 0 1 1 1 1 PhoH-like protein AAA PF00004.24 EIE89436.1 - 0.0031 17.6 3.3 0.0078 16.4 0.2 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) UvrD_C PF13361.1 EIE89436.1 - 0.0033 16.9 0.9 0.13 11.6 0.1 2.5 1 1 1 2 2 2 1 UvrD-like helicase C-terminal domain UvrD_C_2 PF13538.1 EIE89436.1 - 0.0043 17.1 0.0 0.02 14.9 0.0 2.1 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain SNF2_N PF00176.18 EIE89436.1 - 0.0048 15.7 0.1 0.011 14.5 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain PIF1 PF05970.9 EIE89436.1 - 0.0064 15.4 0.0 0.14 11.0 0.0 2.3 2 0 0 2 2 2 1 PIF1-like helicase TK PF00265.13 EIE89436.1 - 0.0065 16.0 0.1 3.4 7.1 0.1 2.6 2 0 0 2 2 2 1 Thymidine kinase Arch_ATPase PF01637.13 EIE89436.1 - 0.0068 16.1 0.1 0.18 11.5 0.0 2.9 2 1 0 2 2 2 1 Archaeal ATPase ABC_tran PF00005.22 EIE89436.1 - 0.0079 16.5 0.0 0.038 14.2 0.0 2.3 1 1 0 1 1 1 1 ABC transporter AAA_5 PF07728.9 EIE89436.1 - 0.0085 15.8 0.0 0.046 13.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 EIE89436.1 - 0.0097 15.3 0.0 0.054 12.9 0.0 2.2 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_14 PF13173.1 EIE89436.1 - 0.011 15.6 0.0 0.17 11.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EIE89436.1 - 0.017 15.4 0.0 0.44 10.8 0.0 2.9 2 1 0 2 2 2 0 AAA domain Flavi_DEAD PF07652.9 EIE89436.1 - 0.024 14.3 0.4 0.15 11.8 0.0 2.2 2 0 0 2 2 2 0 Flavivirus DEAD domain FtsK_SpoIIIE PF01580.13 EIE89436.1 - 0.038 13.4 0.9 0.23 10.8 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family Zot PF05707.7 EIE89436.1 - 0.045 13.2 0.0 0.22 10.9 0.0 2.1 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_17 PF13207.1 EIE89436.1 - 0.049 14.4 0.6 0.21 12.4 0.1 2.5 2 1 0 2 2 1 0 AAA domain RNA_helicase PF00910.17 EIE89436.1 - 0.094 12.9 0.0 0.3 11.2 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.1 EIE89436.1 - 0.11 12.0 0.8 1.2 8.7 0.6 2.3 1 1 0 1 1 1 0 AAA domain CbiA PF01656.18 EIE89436.1 - 0.13 11.6 2.1 0.7 9.2 0.2 2.7 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Syndecan PF01034.15 EIE89438.1 - 0.04 13.5 0.1 0.079 12.6 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain MtrF PF09472.5 EIE89438.1 - 0.04 13.1 0.9 0.066 12.4 0.7 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) EphA2_TM PF14575.1 EIE89438.1 - 0.07 13.5 0.3 0.27 11.6 0.0 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain IgaA PF07095.6 EIE89438.1 - 0.09 10.5 0.3 0.16 9.7 0.1 1.3 1 1 0 1 1 1 0 Intracellular growth attenuator protein IgaA ETRAMP PF09716.5 EIE89438.1 - 0.11 12.4 3.4 0.12 12.3 0.9 2.0 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) DUF2011 PF09428.5 EIE89438.1 - 0.25 11.2 3.8 4.6 7.1 0.0 3.0 3 0 0 3 3 3 0 Fungal protein of unknown function (DUF2011) DUF202 PF02656.10 EIE89439.1 - 1.7e-22 79.4 0.8 2.6e-22 78.8 0.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF202) DUF4293 PF14126.1 EIE89439.1 - 0.014 15.3 0.1 0.023 14.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) Tropomyosin_1 PF12718.2 EIE89440.1 - 3e-10 40.1 24.1 3.6e-10 39.8 16.7 1.1 1 0 0 1 1 1 1 Tropomyosin like Cg6151-P PF10233.4 EIE89440.1 - 8e-10 38.6 17.1 5.5e-06 26.3 6.0 2.3 1 1 1 2 2 2 2 Uncharacterized conserved protein CG6151-P Tropomyosin PF00261.15 EIE89440.1 - 0.00075 18.6 21.9 0.00088 18.4 15.2 1.0 1 0 0 1 1 1 1 Tropomyosin MAD PF05557.8 EIE89440.1 - 0.0015 16.7 13.5 0.002 16.3 9.4 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein Herpes_UL6 PF01763.11 EIE89440.1 - 0.0053 14.9 5.3 0.0071 14.5 3.7 1.1 1 0 0 1 1 1 1 Herpesvirus UL6 like WEMBL PF05701.6 EIE89440.1 - 0.0075 14.7 14.7 0.011 14.2 10.2 1.2 1 0 0 1 1 1 1 Weak chloroplast movement under blue light Rootletin PF15035.1 EIE89440.1 - 0.0099 15.8 10.1 0.015 15.3 7.0 1.3 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion Mod_r PF07200.8 EIE89440.1 - 0.017 15.0 15.6 0.023 14.6 10.8 1.1 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein DUF4149 PF13664.1 EIE89440.1 - 0.019 14.9 1.7 0.019 14.9 1.2 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4149) ADIP PF11559.3 EIE89440.1 - 0.038 13.8 15.5 0.038 13.8 8.7 1.9 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF3450 PF11932.3 EIE89440.1 - 0.073 12.3 8.4 0.15 11.2 5.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) AAA_23 PF13476.1 EIE89440.1 - 0.091 13.0 9.8 0.14 12.5 6.8 1.3 1 0 0 1 1 1 0 AAA domain Striatin PF08232.7 EIE89440.1 - 0.18 12.0 11.5 0.27 11.5 8.0 1.2 1 0 0 1 1 1 0 Striatin family DUF4139 PF13598.1 EIE89440.1 - 0.25 10.6 1.8 0.33 10.2 1.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4139) ATG16 PF08614.6 EIE89440.1 - 0.36 10.6 18.3 0.6 9.9 12.1 1.5 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DMPK_coil PF08826.5 EIE89440.1 - 0.42 10.5 21.3 0.63 9.9 5.4 2.7 1 1 1 2 2 2 0 DMPK coiled coil domain like Nup54 PF13874.1 EIE89440.1 - 0.69 9.5 8.0 1.6 8.4 5.6 1.7 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 TMF_TATA_bd PF12325.3 EIE89440.1 - 0.77 9.4 19.1 2 8.1 13.2 1.6 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding BLOC1_2 PF10046.4 EIE89440.1 - 1.2 9.2 15.3 1.3 9.1 6.9 2.2 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Nsp1_C PF05064.8 EIE89440.1 - 1.4 8.5 13.3 2.3 7.8 1.6 2.1 1 1 1 2 2 2 0 Nsp1-like C-terminal region DUF3829 PF12889.2 EIE89440.1 - 2.2 7.3 12.2 2.8 7.0 8.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) V_ATPase_I PF01496.14 EIE89440.1 - 2.3 5.9 10.6 3.8 5.2 7.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIC PF04977.10 EIE89440.1 - 2.5 7.6 16.1 2.6 7.5 4.7 2.6 1 1 1 2 2 2 0 Septum formation initiator Fib_alpha PF08702.5 EIE89440.1 - 3.3 7.8 7.8 1.3 9.1 2.0 2.1 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Laminin_II PF06009.7 EIE89440.1 - 6 6.6 12.3 9.9 5.9 8.2 1.6 1 1 1 2 2 2 0 Laminin Domain II MFS_1 PF07690.11 EIE89441.1 - 2.3e-33 115.3 32.0 2.3e-33 115.3 22.2 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.11 EIE89442.1 - 4.3e-40 137.4 37.1 4.3e-40 137.4 25.7 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3139 PF11337.3 EIE89442.1 - 0.22 11.8 0.1 0.22 11.8 0.1 3.6 5 0 0 5 5 5 0 Protein of unknown function (DUF3139) RVT_1 PF00078.22 EIE89443.1 - 3.3e-15 56.0 0.0 3.6e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) USP8_interact PF08941.5 EIE89443.1 - 0.041 13.1 0.0 0.06 12.6 0.0 1.2 1 0 0 1 1 1 0 USP8 interacting SpoIIE PF07228.7 EIE89445.1 - 1.5e-15 57.3 0.0 2.3e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 EIE89445.1 - 2.3e-06 27.1 0.0 7e-06 25.5 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 EIE89445.1 - 1.2e-05 24.8 0.1 0.044 13.1 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C DUF3583 PF12126.3 EIE89445.1 - 0.078 12.0 0.1 7.9 5.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3583) zf-RING_2 PF13639.1 EIE89448.1 - 2e-13 49.9 8.6 3.3e-13 49.2 6.0 1.4 1 0 0 1 1 1 1 Ring finger domain PA PF02225.17 EIE89448.1 - 6.4e-10 38.6 0.0 9.8e-10 38.0 0.0 1.3 1 0 0 1 1 1 1 PA domain zf-rbx1 PF12678.2 EIE89448.1 - 2.6e-09 37.0 3.0 5.6e-09 35.9 2.1 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EIE89448.1 - 4.4e-09 35.8 4.7 8.6e-09 34.9 3.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EIE89448.1 - 7.6e-08 31.9 5.4 1.4e-07 31.0 3.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIE89448.1 - 4.9e-07 29.6 5.0 9.8e-07 28.7 3.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIE89448.1 - 4.9e-06 26.1 7.2 8e-06 25.4 5.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EIE89448.1 - 0.0002 21.1 4.8 0.00052 19.8 3.4 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EIE89448.1 - 0.00077 18.9 4.2 0.0015 18.1 2.9 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RINGv PF12906.2 EIE89448.1 - 0.027 14.5 2.7 0.071 13.1 1.9 1.7 1 1 0 1 1 1 0 RING-variant domain FANCL_C PF11793.3 EIE89448.1 - 0.23 11.4 8.1 3.3 7.7 5.5 2.6 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.24 EIE89448.1 - 1.4 8.7 7.1 2.6 7.8 4.9 1.5 1 0 0 1 1 1 0 PHD-finger Vps39_2 PF10367.4 EIE89448.1 - 1.6 8.9 5.8 13 6.0 0.1 2.4 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 Rifin_STEVOR PF02009.11 EIE89450.1 - 2.3e-05 24.2 0.0 2.6e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Rifin/stevor family UPF0506 PF11703.3 EIE89450.1 - 0.00089 19.1 6.4 0.0024 17.7 4.4 1.7 1 0 0 1 1 1 1 UPF0506 DUF2370 PF10176.4 EIE89450.1 - 0.012 14.9 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) EB PF01683.13 EIE89450.1 - 0.024 14.7 10.5 0.026 14.5 6.1 2.0 2 0 0 2 2 2 0 EB module Actino_peptide PF14408.1 EIE89450.1 - 0.054 13.4 0.1 1.3 8.9 0.0 2.6 2 1 0 2 2 2 0 Ribosomally synthesized peptide in actinomycetes DUF2106 PF09879.4 EIE89450.1 - 0.067 12.5 0.1 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2106) Colipase PF01114.13 EIE89450.1 - 5.5 6.5 8.8 2.9 7.4 4.4 1.8 1 1 1 2 2 2 0 Colipase, N-terminal domain DUF16 PF01519.11 EIE89451.1 - 0.04 14.1 1.2 0.044 14.0 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF16 Baculo_PEP_C PF04513.7 EIE89451.1 - 0.12 12.2 1.0 0.14 12.0 0.7 1.0 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus OmpH PF03938.9 EIE89451.1 - 0.18 11.7 2.5 0.2 11.5 1.7 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) XPG_I PF00867.13 EIE89452.1 - 5.8e-21 74.3 0.0 9.7e-21 73.6 0.0 1.3 1 0 0 1 1 1 1 XPG I-region DUF4142 PF13628.1 EIE89452.1 - 0.049 13.6 0.3 0.063 13.3 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4142) TFR_dimer PF04253.10 EIE89453.1 - 2.5e-13 49.6 0.1 4.6e-13 48.8 0.1 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 EIE89453.1 - 2.3e-07 30.7 0.0 5.5e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EIE89453.1 - 0.0039 16.8 0.0 0.011 15.3 0.0 1.8 1 0 0 1 1 1 1 PA domain Pkinase PF00069.20 EIE89454.1 - 1.7e-13 50.3 0.0 3.3e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE89454.1 - 6.1e-12 45.1 0.0 1e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HECT PF00632.20 EIE89455.1 - 1.6e-22 80.1 0.0 3.8e-22 78.8 0.0 1.6 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF3102 PF11300.3 EIE89455.1 - 0.059 13.4 0.8 1.2 9.2 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3102) Terminase_GpA PF05876.7 EIE89455.1 - 0.13 10.6 0.0 0.21 9.8 0.0 1.2 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) PAPA-1 PF04795.7 EIE89456.1 - 7.6e-16 58.5 6.4 7.6e-16 58.5 4.4 1.8 2 0 0 2 2 2 1 PAPA-1-like conserved region zf-HIT PF04438.11 EIE89456.1 - 0.024 14.2 1.9 0.032 13.8 1.3 1.2 1 0 0 1 1 1 0 HIT zinc finger HemX PF04375.9 EIE89456.1 - 0.58 8.6 6.8 0.74 8.3 4.7 1.1 1 0 0 1 1 1 0 HemX IncA PF04156.9 EIE89456.1 - 1.1 8.7 6.5 1.6 8.2 4.5 1.1 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 EIE89456.1 - 4.3 6.2 9.1 5.5 5.9 6.3 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 NDUFB10 PF10249.4 EIE89457.1 - 2.4e-08 34.2 0.6 2.5e-08 34.1 0.4 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 PH_4 PF15404.1 EIE89457.1 - 0.097 12.1 0.1 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Pleckstrin homology domain CSTF2_hinge PF14327.1 EIE89459.1 - 4e-23 81.2 6.1 4e-23 81.2 4.2 3.1 3 2 0 3 3 3 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.17 EIE89459.1 - 4.3e-21 74.3 0.1 9.8e-21 73.1 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE89459.1 - 7.2e-14 51.5 0.0 1.8e-13 50.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 EIE89459.1 - 1.4e-08 33.8 10.6 4.7e-08 32.1 7.4 1.9 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal RRM_5 PF13893.1 EIE89459.1 - 3.4e-08 33.2 0.0 5.8e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MgtE_N PF03448.12 EIE89459.1 - 0.24 11.7 2.8 2.7 8.3 0.0 2.9 3 0 0 3 3 3 0 MgtE intracellular N domain WD40 PF00400.27 EIE89460.1 - 1.9e-09 36.9 3.4 0.00022 20.9 0.1 5.2 6 0 0 6 6 6 2 WD domain, G-beta repeat Toxin_40 PF15520.1 EIE89460.1 - 0.14 11.6 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 Putative toxin 40 Lgl_C PF08596.5 EIE89461.1 - 2.3e-11 42.7 0.2 3.2e-11 42.3 0.1 1.2 1 0 0 1 1 1 1 Lethal giant larvae(Lgl) like, C-terminal Synaptobrevin PF00957.16 EIE89461.1 - 0.0015 18.1 0.2 0.0038 16.7 0.1 1.7 1 0 0 1 1 1 1 Synaptobrevin YkyA PF10368.4 EIE89461.1 - 8.1 5.7 10.7 0.69 9.2 2.9 2.2 2 1 0 2 2 2 0 Putative cell-wall binding lipoprotein CRM1_C PF08767.6 EIE89462.1 - 3.5e-116 387.5 6.7 3.5e-116 387.5 4.7 2.4 2 1 0 2 2 2 1 CRM1 C terminal Xpo1 PF08389.7 EIE89462.1 - 0.062 13.1 7.1 13 5.6 0.3 4.2 2 1 2 4 4 4 0 Exportin 1-like protein DUF3385 PF11865.3 EIE89462.1 - 0.13 12.2 3.6 0.21 11.4 0.0 3.0 3 1 1 4 4 4 0 Domain of unknown function (DUF3385) Glyco_transf_8 PF01501.15 EIE89463.1 - 1.5e-35 122.7 0.0 5.9e-35 120.7 0.0 2.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 PTH2 PF01981.11 EIE89464.1 - 1.2e-39 134.5 0.1 1.8e-39 134.0 0.0 1.3 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 TraH_2 PF06871.6 EIE89464.1 - 0.054 12.9 0.0 0.079 12.4 0.0 1.2 1 0 0 1 1 1 0 TraH_2 DUF1161 PF06649.7 EIE89464.1 - 0.08 12.8 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1161) CorA PF01544.13 EIE89467.1 - 9.5e-46 156.1 7.8 9.5e-46 156.1 5.4 1.9 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein DPBB_1 PF03330.13 EIE89468.1 - 3.7e-11 42.8 0.0 5e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EIE89468.1 - 0.0013 18.3 0.1 0.0018 17.9 0.1 1.2 1 0 0 1 1 1 1 Barwin family zf-ribbon_3 PF13248.1 EIE89468.1 - 0.12 11.6 1.4 2.4 7.4 0.1 2.8 3 0 0 3 3 3 0 zinc-ribbon domain SIR2 PF02146.12 EIE89469.1 - 3.2e-61 206.1 0.0 4.7e-61 205.5 0.0 1.3 1 0 0 1 1 1 1 Sir2 family PITH PF06201.8 EIE89470.1 - 1.3e-44 151.5 6.7 2.3e-44 150.8 4.6 1.4 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.15 EIE89470.1 - 1.4e-28 98.6 0.5 3.5e-28 97.3 0.4 1.7 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EIE89470.1 - 1.1e-06 28.8 0.5 1.2e-05 25.4 0.3 2.4 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EIE89470.1 - 8.5e-05 22.5 0.5 0.00024 21.1 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.1 EIE89470.1 - 0.00054 19.5 0.2 0.0014 18.1 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin UbiA PF01040.13 EIE89471.1 - 4.4e-24 85.1 15.2 5.3e-24 84.8 10.5 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Pkinase PF00069.20 EIE89472.1 - 1e-64 218.2 0.0 1.3e-64 217.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE89472.1 - 6.1e-32 110.6 0.0 8.2e-32 110.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE89472.1 - 1.4e-06 27.5 0.0 1.8e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EIE89472.1 - 0.00012 21.2 0.0 0.0002 20.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EIE89472.1 - 0.00018 20.8 0.2 0.00046 19.5 0.0 1.7 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL APH PF01636.18 EIE89472.1 - 0.0051 16.5 0.1 0.009 15.7 0.1 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family HMG-CoA_red PF00368.13 EIE89473.1 - 3e-161 536.2 6.6 5.2e-161 535.4 4.6 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Sterol-sensing PF12349.3 EIE89473.1 - 1.2e-15 57.2 4.1 2.9e-15 56.0 2.9 1.6 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 EIE89473.1 - 6.8e-07 27.6 6.7 9.6e-07 27.1 4.6 1.2 1 0 0 1 1 1 1 Patched family Globin PF00042.17 EIE89474.1 - 1.1e-08 35.3 0.1 2.8e-06 27.6 0.0 3.0 2 1 0 2 2 2 1 Globin NIT PF08376.5 EIE89474.1 - 0.016 14.7 0.0 0.024 14.1 0.0 1.2 1 0 0 1 1 1 0 Nitrate and nitrite sensing PA28_beta PF02252.13 EIE89474.1 - 0.048 13.1 0.0 0.085 12.3 0.0 1.4 1 0 0 1 1 1 0 Proteasome activator pa28 beta subunit RVT_1 PF00078.22 EIE89475.1 - 6.6e-35 120.4 0.1 1.9e-34 118.9 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.1 EIE89475.1 - 1.5e-05 25.2 0.9 5.4e-05 23.4 0.6 2.0 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Rtt102p PF09510.5 EIE89476.1 - 0.13 12.2 0.2 0.13 12.2 0.1 2.5 3 0 0 3 3 3 0 Rtt102p-like transcription regulator protein RRM_1 PF00076.17 EIE89476.1 - 0.13 11.9 2.0 0.78 9.4 0.0 3.1 4 0 0 4 4 4 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.18 EIE89476.1 - 0.44 10.5 2.7 1.3 9.1 0.2 2.2 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.1 EIE89476.1 - 1.9 8.2 8.7 0.54 9.9 0.5 2.8 3 0 0 3 3 3 0 Zinc knuckle DDE_3 PF13358.1 EIE89477.1 - 5.8e-08 32.6 0.0 7.8e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Rtt102p PF09510.5 EIE89478.1 - 0.13 12.2 0.2 0.13 12.2 0.1 2.5 3 0 0 3 3 3 0 Rtt102p-like transcription regulator protein RRM_1 PF00076.17 EIE89478.1 - 0.13 11.9 2.0 0.78 9.4 0.0 3.1 4 0 0 4 4 4 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.18 EIE89478.1 - 0.44 10.5 2.7 1.3 9.1 0.2 2.2 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.1 EIE89478.1 - 1.9 8.2 8.7 0.54 9.9 0.5 2.8 3 0 0 3 3 3 0 Zinc knuckle RVT_1 PF00078.22 EIE89479.1 - 6.6e-35 120.4 0.1 1.9e-34 118.9 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.1 EIE89479.1 - 1.5e-05 25.2 0.9 5.4e-05 23.4 0.6 2.0 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase DER1 PF04511.10 EIE89480.1 - 1.5e-19 70.2 0.1 1.7e-19 70.0 0.1 1.0 1 0 0 1 1 1 1 Der1-like family Cor1 PF04803.7 EIE89481.1 - 0.11 12.2 0.8 0.12 12.1 0.6 1.1 1 0 0 1 1 1 0 Cor1/Xlr/Xmr conserved region zf-MYND PF01753.13 EIE89482.1 - 0.00046 20.0 14.3 0.00046 20.0 9.9 2.5 3 0 0 3 3 3 1 MYND finger SET PF00856.23 EIE89482.1 - 0.011 16.0 0.0 0.021 15.1 0.0 1.5 1 0 0 1 1 1 0 SET domain Glutaredoxin PF00462.19 EIE89484.1 - 1.5e-18 66.4 0.0 2.3e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin HMG_box PF00505.14 EIE89485.1 - 1.7e-17 63.4 0.2 1.7e-17 63.4 0.2 2.1 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EIE89485.1 - 2.6e-11 43.7 0.3 2.6e-11 43.7 0.2 2.3 3 0 0 3 3 3 1 HMG-box domain Tol_Tol_Ttg2 PF05494.7 EIE89485.1 - 0.0025 17.3 0.1 0.0056 16.2 0.0 1.5 1 0 0 1 1 1 1 Toluene tolerance, Ttg2 PSCyt1 PF07635.6 EIE89485.1 - 0.098 12.9 0.4 9.9 6.5 0.1 2.4 2 0 0 2 2 2 0 Planctomycete cytochrome C Ligase_CoA PF00549.14 EIE89486.1 - 8.2e-17 61.2 0.1 1.5e-16 60.3 0.1 1.5 1 0 0 1 1 1 1 CoA-ligase Citrate_synt PF00285.16 EIE89486.1 - 5.3e-15 55.0 0.0 2.2e-13 49.7 0.0 2.7 1 1 1 2 2 2 1 Citrate synthase CoA_binding PF02629.14 EIE89486.1 - 1.6e-12 47.7 0.0 3.5e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 CoA binding domain ATP-grasp_2 PF08442.5 EIE89486.1 - 9.8e-10 38.1 0.0 1.8e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.1 EIE89486.1 - 1.1e-05 24.9 0.2 2.8e-05 23.7 0.0 1.8 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain zf-C2H2_4 PF13894.1 EIE89487.1 - 6.9e-10 38.5 11.7 0.00016 21.7 0.8 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EIE89487.1 - 1e-09 38.1 11.7 8e-05 22.7 0.7 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIE89487.1 - 2.7e-07 30.5 2.3 2.7e-07 30.5 1.6 3.3 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 EIE89487.1 - 0.071 13.0 0.4 0.071 13.0 0.3 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger RPAP2_Rtr1 PF04181.8 EIE89487.1 - 0.23 11.5 4.2 25 5.0 2.9 2.3 1 1 0 1 1 1 0 Rtr1/RPAP2 family FKS1_dom1 PF14288.1 EIE89487.1 - 0.62 9.9 3.6 3.8 7.4 2.5 2.1 1 1 0 1 1 1 0 1,3-beta-glucan synthase subunit FKS1, domain-1 zf-RING_4 PF14570.1 EIE89488.1 - 3.1e-21 74.6 10.9 5.7e-21 73.8 7.6 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.1 EIE89488.1 - 0.042 13.8 12.1 0.082 12.9 8.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.1 EIE89488.1 - 0.11 12.3 4.1 0.3 10.8 2.8 1.7 1 0 0 1 1 1 0 Zinc-binding RING-finger Baculo_IE-1 PF05290.6 EIE89488.1 - 0.14 11.8 3.8 0.4 10.4 2.6 1.7 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-C3HC4 PF00097.20 EIE89488.1 - 0.64 9.7 11.4 1.2 8.8 7.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RIC1 PF07064.8 EIE89489.1 - 8.3e-37 127.0 1.1 3.5e-35 121.7 0.4 2.9 3 1 0 3 3 3 1 RIC1 Apc4_WD40 PF12894.2 EIE89489.1 - 0.076 12.5 0.0 0.27 10.7 0.0 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.1 EIE89489.1 - 0.078 11.9 0.2 0.29 10.0 0.0 1.8 1 1 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus WD40 PF00400.27 EIE89489.1 - 0.44 10.5 6.0 29 4.7 0.6 4.1 5 0 0 5 5 5 0 WD domain, G-beta repeat tRNA-synt_2b PF00587.20 EIE89491.1 - 5.2e-45 153.1 0.0 1e-44 152.1 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EIE89491.1 - 6.9e-22 77.1 0.0 1.8e-21 75.9 0.0 1.7 2 0 0 2 2 2 1 Anticodon binding domain PAT1 PF09770.4 EIE89492.1 - 7.9 4.5 14.8 8.7 4.4 10.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Fe-S_biosyn PF01521.15 EIE89493.1 - 7.3e-20 70.9 0.0 9.2e-20 70.6 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Lysyl_oxidase PF01186.12 EIE89494.1 - 0.0089 15.6 0.1 0.01 15.5 0.1 1.1 1 0 0 1 1 1 1 Lysyl oxidase Fib_alpha PF08702.5 EIE89495.1 - 0.027 14.6 4.1 2.1 8.4 0.0 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF3665 PF12427.3 EIE89495.1 - 0.17 11.2 0.4 2 7.8 0.0 2.3 2 0 0 2 2 2 0 Branched-chain amino acid aminotransferase DUF2419 PF10343.4 EIE89496.1 - 0.11 11.7 0.5 0.18 11.0 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2419) zf-CCHC PF00098.18 EIE89498.1 - 1.8e-05 24.4 11.2 0.0024 17.7 0.9 2.3 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 EIE89498.1 - 0.0022 17.6 5.0 0.011 15.3 0.2 2.5 2 0 0 2 2 2 1 Zinc knuckle Macin PF14865.1 EIE89498.1 - 0.022 14.8 2.1 0.26 11.3 1.6 2.4 1 1 1 2 2 2 0 Macin RRM_1 PF00076.17 EIE89498.1 - 0.023 14.3 0.0 0.1 12.2 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Zn_ribbon_2 PF12674.2 EIE89498.1 - 1.2 9.5 6.7 13 6.2 1.2 2.5 1 1 1 2 2 2 0 Putative zinc ribbon domain zf-CCHC_3 PF13917.1 EIE89498.1 - 1.5 8.5 8.1 1.5 8.6 0.1 2.3 1 1 1 2 2 2 0 Zinc knuckle RVT_1 PF00078.22 EIE89499.1 - 2.9e-36 124.8 0.0 4.3e-36 124.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_3 PF13358.1 EIE89500.1 - 0.001 18.7 0.1 0.0027 17.4 0.0 1.7 1 1 1 2 2 2 1 DDE superfamily endonuclease zf-CCHC PF00098.18 EIE89501.1 - 1.8e-05 24.4 11.2 0.0024 17.7 0.9 2.3 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 EIE89501.1 - 0.0022 17.6 5.0 0.011 15.3 0.2 2.5 2 0 0 2 2 2 1 Zinc knuckle Macin PF14865.1 EIE89501.1 - 0.022 14.8 2.1 0.26 11.3 1.6 2.4 1 1 1 2 2 2 0 Macin RRM_1 PF00076.17 EIE89501.1 - 0.023 14.3 0.0 0.1 12.2 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Zn_ribbon_2 PF12674.2 EIE89501.1 - 1.2 9.5 6.7 13 6.2 1.2 2.5 1 1 1 2 2 2 0 Putative zinc ribbon domain zf-CCHC_3 PF13917.1 EIE89501.1 - 1.5 8.5 8.1 1.5 8.6 0.1 2.3 1 1 1 2 2 2 0 Zinc knuckle BMF PF15185.1 EIE89502.1 - 0.015 14.5 0.0 0.017 14.4 0.0 1.2 1 0 0 1 1 1 0 Bcl-2-modifying factor, apoptosis DUF3545 PF12065.3 EIE89502.1 - 0.092 12.5 3.6 0.14 11.8 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3545) DUF2093 PF09866.4 EIE89503.1 - 0.013 14.6 0.4 2.7 7.2 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2093) Lar_restr_allev PF14354.1 EIE89504.1 - 0.015 15.5 0.4 0.033 14.4 0.3 1.5 1 0 0 1 1 1 0 Restriction alleviation protein Lar DUF2296 PF10058.4 EIE89504.1 - 0.031 14.0 0.3 0.074 12.8 0.2 1.5 1 0 0 1 1 1 0 Predicted integral membrane metal-binding protein (DUF2296) Zn-ribbon_8 PF09723.5 EIE89504.1 - 0.039 13.9 2.4 5.1 7.1 0.1 2.5 2 0 0 2 2 2 0 Zinc ribbon domain NPV_P10 PF05531.7 EIE89504.1 - 0.062 13.5 0.4 0.23 11.7 0.3 1.9 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein LRR_4 PF12799.2 EIE89504.1 - 0.071 12.7 0.0 0.2 11.3 0.0 1.7 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) zf-ISL3 PF14690.1 EIE89504.1 - 0.083 12.9 1.5 0.78 9.8 0.5 2.5 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 OrfB_Zn_ribbon PF07282.6 EIE89504.1 - 0.11 12.1 0.5 5.6 6.6 0.1 2.5 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Zn_Tnp_IS1595 PF12760.2 EIE89504.1 - 0.17 11.7 4.4 0.59 9.9 3.1 1.9 1 1 0 1 1 1 0 Transposase zinc-ribbon domain DnaJ_CXXCXGXG PF00684.14 EIE89504.1 - 0.17 11.9 1.4 0.37 10.8 0.9 1.5 1 0 0 1 1 1 0 DnaJ central domain HypA PF01155.14 EIE89504.1 - 0.21 11.2 2.2 6.5 6.4 1.5 2.4 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-H2C2_2 PF13465.1 EIE89504.1 - 0.25 11.7 3.7 14 6.2 0.1 2.7 2 0 0 2 2 2 0 Zinc-finger double domain Zn_Tnp_IS1 PF03811.8 EIE89504.1 - 0.35 10.3 2.7 0.97 8.9 1.9 1.8 1 0 0 1 1 1 0 InsA N-terminal domain zf-Mss51 PF13824.1 EIE89504.1 - 0.71 9.7 3.6 0.47 10.3 0.8 2.0 2 0 0 2 2 1 0 Zinc-finger of mitochondrial splicing suppressor 51 FlgN PF05130.7 EIE89504.1 - 1.1 9.4 11.7 2.6 8.2 1.8 2.8 3 0 0 3 3 3 0 FlgN protein ADIP PF11559.3 EIE89504.1 - 2 8.2 10.0 4.4 7.1 1.8 2.5 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding THOC7 PF05615.8 EIE89504.1 - 3.1 8.0 8.9 0.25 11.5 0.3 2.8 3 0 0 3 3 3 0 Tho complex subunit 7 DUF2046 PF09755.4 EIE89504.1 - 4.9 5.9 9.8 0.29 10.0 0.5 2.7 3 0 0 3 3 3 0 Uncharacterized conserved protein H4 (DUF2046) TFIIS_C PF01096.13 EIE89504.1 - 9.8 5.9 9.5 0.092 12.3 0.7 2.2 2 0 0 2 2 1 0 Transcription factor S-II (TFIIS) NUC153 PF08159.7 EIE89505.1 - 0.038 13.5 0.1 0.065 12.8 0.1 1.4 1 0 0 1 1 1 0 NUC153 domain GCR1_C PF12550.3 EIE89506.1 - 2e-13 50.0 0.3 3.3e-13 49.3 0.2 1.4 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes DUF465 PF04325.8 EIE89506.1 - 0.071 12.8 0.1 0.2 11.3 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF465) Mlp PF03304.8 EIE89507.1 - 0.13 12.2 5.7 0.11 12.4 0.3 2.4 2 0 0 2 2 2 0 Mlp lipoprotein family SET PF00856.23 EIE89509.1 - 1.1e-24 87.5 2.5 5e-24 85.4 0.1 3.2 3 1 0 3 3 3 1 SET domain WW PF00397.21 EIE89509.1 - 2.5e-08 33.6 0.4 2.5e-08 33.6 0.3 2.0 2 0 0 2 2 2 1 WW domain SRI PF08236.6 EIE89509.1 - 7.1e-06 25.8 2.5 7.1e-06 25.8 1.7 2.4 2 0 0 2 2 2 1 SRI (Set2 Rpb1 interacting) domain Med26 PF08711.6 EIE89509.1 - 0.0012 18.3 0.1 0.025 14.0 0.0 2.9 2 0 0 2 2 2 1 TFIIS helical bundle-like domain RGS PF00615.14 EIE89509.1 - 0.0028 17.7 3.3 0.72 9.9 0.2 3.9 3 2 0 3 3 3 2 Regulator of G protein signaling domain Flavi_capsid PF01003.14 EIE89509.1 - 0.12 11.9 0.4 0.26 10.8 0.3 1.5 1 0 0 1 1 1 0 Flavivirus capsid protein C Glyco_hydro_47 PF01532.15 EIE89511.1 - 1.3e-119 399.8 1.9 8.8e-101 337.7 0.1 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 47 C5-epim_C PF06662.8 EIE89511.1 - 0.026 13.8 2.0 1.4 8.1 0.1 3.2 2 1 1 3 3 3 0 D-glucuronyl C5-epimerase C-terminus PA PF02225.17 EIE89512.1 - 2.7e-09 36.6 0.0 3.5e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 PA domain LNS2 PF08235.8 EIE89513.1 - 7.3e-69 230.3 0.1 1.4e-68 229.4 0.0 1.5 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) PS_Dcarbxylase PF02666.10 EIE89514.1 - 3.5e-77 258.2 0.0 2.9e-75 251.9 0.0 2.3 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase DNA_pol_E_B PF04042.11 EIE89514.1 - 4.9e-42 143.5 0.1 9.1e-42 142.6 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B eIF-1a PF01176.14 EIE89514.1 - 1.2e-12 47.1 0.0 2.5e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Ribosomal_L6e PF01159.14 EIE89517.1 - 5e-34 116.7 0.8 5e-34 116.7 0.5 1.7 2 0 0 2 2 2 1 Ribosomal protein L6e Ribosomal_L6e_N PF03868.10 EIE89517.1 - 1.6e-14 53.5 1.0 1.6e-14 53.5 0.7 2.2 2 1 0 2 2 2 1 Ribosomal protein L6, N-terminal domain Na_Ca_ex PF01699.19 EIE89518.1 - 2.1e-24 85.7 14.5 1.1e-22 80.1 6.9 2.6 2 0 0 2 2 2 2 Sodium/calcium exchanger protein SET PF00856.23 EIE89518.1 - 2.2e-24 86.6 0.4 2.2e-24 86.6 0.3 3.6 4 1 0 4 4 4 1 SET domain N-SET PF11764.3 EIE89518.1 - 4.7e-07 29.8 1.1 4.7e-07 29.8 0.8 4.8 3 1 1 4 4 4 1 COMPASS (Complex proteins associated with Set1p) component N RRM_1 PF00076.17 EIE89518.1 - 8.4e-06 25.3 0.0 0.00048 19.6 0.0 3.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE89518.1 - 0.00016 21.5 0.0 0.0033 17.3 0.0 2.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.3 EIE89518.1 - 0.0019 17.4 0.0 0.0045 16.2 0.0 1.7 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated Transferase PF02458.10 EIE89519.1 - 3.9e-43 147.5 0.0 4.8e-43 147.2 0.0 1.1 1 0 0 1 1 1 1 Transferase family EF-hand_4 PF12763.2 EIE89520.1 - 1.8e-18 66.1 0.0 5.4e-18 64.6 0.0 1.8 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 EIE89520.1 - 2.8e-06 27.3 0.0 1.2e-05 25.2 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EIE89520.1 - 9.7e-05 21.4 0.0 0.016 14.4 0.0 2.7 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 EIE89520.1 - 0.0055 16.4 0.0 4.5 7.4 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain CesT PF05932.8 EIE89520.1 - 0.067 13.0 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Tir chaperone protein (CesT) family APG6 PF04111.7 EIE89520.1 - 0.087 11.8 11.3 0.06 12.3 0.7 2.4 2 0 0 2 2 2 0 Autophagy protein Apg6 Anti-adapt_IraP PF10796.4 EIE89520.1 - 0.14 12.5 4.1 0.1 12.9 0.9 2.2 2 0 0 2 2 2 0 Sigma-S stabilisation anti-adaptor protein PAP2_3 PF14378.1 EIE89520.1 - 0.24 10.8 0.0 1.8 8.0 0.0 2.0 2 0 0 2 2 2 0 PAP2 superfamily Syntaxin PF00804.20 EIE89520.1 - 0.61 10.2 12.5 0.76 9.9 0.7 3.5 2 1 0 3 3 3 0 Syntaxin DUF1192 PF06698.6 EIE89520.1 - 1.6 8.5 7.7 0.28 11.0 0.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) Syntaxin-6_N PF09177.6 EIE89520.1 - 5.2 7.5 12.8 0.92 9.9 0.8 3.8 4 1 0 4 4 4 0 Syntaxin 6, N-terminal IncA PF04156.9 EIE89520.1 - 6.3 6.3 10.3 6.9 6.2 2.2 2.8 2 0 0 2 2 2 0 IncA protein DivIC PF04977.10 EIE89520.1 - 9.4 5.8 21.7 2.3 7.7 0.0 5.8 5 1 1 6 6 6 0 Septum formation initiator Peptidase_M3 PF01432.15 EIE89521.1 - 2.4e-123 412.5 0.2 3.9e-123 411.8 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M3 RabGAP-TBC PF00566.13 EIE89522.1 - 1.5e-33 116.0 0.9 3.5e-33 114.8 0.6 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain TPR_11 PF13414.1 EIE89523.1 - 8.7e-35 118.2 4.0 1.3e-16 59.9 0.4 3.6 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 EIE89523.1 - 1.5e-24 84.5 2.8 1.3e-09 37.2 0.0 5.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 EIE89523.1 - 1.6e-24 83.7 1.9 2.3e-08 33.3 0.0 5.2 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_12 PF13424.1 EIE89523.1 - 2.2e-24 85.1 5.9 1.8e-10 40.6 0.1 3.7 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 EIE89523.1 - 4.3e-19 66.7 3.8 1e-06 28.0 0.0 5.1 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 EIE89523.1 - 6.8e-17 60.2 0.5 7e-06 25.8 0.0 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 EIE89523.1 - 8.1e-15 55.0 0.2 1.1e-07 32.2 0.0 3.3 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 EIE89523.1 - 1.4e-14 54.1 5.8 2.3e-08 34.2 0.1 3.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 EIE89523.1 - 2.2e-13 49.6 2.3 0.00026 21.2 0.0 4.4 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 EIE89523.1 - 1.2e-12 46.6 0.3 4e-05 23.0 0.0 4.1 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 EIE89523.1 - 1.4e-11 43.9 0.1 0.0087 16.6 0.1 5.0 2 1 3 5 5 5 3 Tetratricopeptide repeat Apc3 PF12895.2 EIE89523.1 - 3e-11 43.2 3.7 4e-08 33.2 0.1 2.3 2 1 1 3 3 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 EIE89523.1 - 1.9e-08 33.9 0.2 0.3 11.0 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.1 EIE89523.1 - 8.8e-06 25.4 0.0 0.00047 19.9 0.0 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat Paf67 PF10255.4 EIE89523.1 - 4.2e-05 22.6 0.2 0.00069 18.5 0.2 2.0 1 1 1 2 2 2 1 RNA polymerase I-associated factor PAF67 TPR_15 PF13429.1 EIE89523.1 - 0.00011 21.3 0.1 0.00029 19.9 0.1 1.8 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_20 PF14561.1 EIE89523.1 - 0.00014 21.9 1.0 0.023 14.7 0.1 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat YfiO PF13525.1 EIE89523.1 - 0.0015 18.0 0.3 0.0025 17.3 0.2 1.3 1 0 0 1 1 1 1 Outer membrane lipoprotein Foie-gras_1 PF11817.3 EIE89523.1 - 0.0064 16.0 0.6 7.7 5.9 0.0 3.0 1 1 2 3 3 3 0 Foie gras liver health family 1 TPR_5 PF12688.2 EIE89523.1 - 0.026 14.5 0.1 0.27 11.2 0.0 2.3 2 0 0 2 2 2 0 Tetratrico peptide repeat Coatomer_E PF04733.9 EIE89523.1 - 0.036 13.2 0.0 0.071 12.2 0.0 1.6 1 0 0 1 1 1 0 Coatomer epsilon subunit BTAD PF03704.12 EIE89523.1 - 0.036 14.3 0.2 0.24 11.7 0.1 2.1 1 1 1 2 2 2 0 Bacterial transcriptional activator domain RPN7 PF10602.4 EIE89523.1 - 0.045 13.1 5.2 0.19 11.0 0.2 3.5 1 1 2 4 4 4 0 26S proteasome subunit RPN7 DUF3366 PF11846.3 EIE89523.1 - 0.056 13.3 0.0 1.6 8.5 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3366) EST1_DNA_bind PF10373.4 EIE89523.1 - 0.065 12.4 0.6 0.32 10.1 0.4 1.9 1 1 0 1 1 1 0 Est1 DNA/RNA binding domain TPR_3 PF07720.7 EIE89523.1 - 0.11 12.2 0.9 2.6 7.9 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3856 PF12968.2 EIE89523.1 - 0.2 11.4 1.3 7.5 6.3 0.1 3.0 1 1 1 2 2 2 0 Domain of Unknown Function (DUF3856) Sec15 PF04091.7 EIE89524.1 - 1.4e-48 165.8 1.1 1.4e-48 165.8 0.7 2.8 3 0 0 3 3 3 1 Exocyst complex subunit Sec15-like Vps51 PF08700.6 EIE89524.1 - 9e-06 25.4 3.1 1.5e-05 24.7 0.1 2.9 2 0 0 2 2 2 1 Vps51/Vps67 COG2 PF06148.6 EIE89524.1 - 0.0012 18.7 4.1 0.0012 18.7 2.8 3.0 3 0 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 Sec8_exocyst PF04048.9 EIE89524.1 - 0.0013 18.3 7.2 0.0015 18.1 2.9 2.7 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain Eno-Rase_FAD_bd PF07055.7 EIE89524.1 - 0.087 12.7 1.1 6.4 6.8 0.0 3.9 3 0 0 3 3 3 0 Enoyl reductase FAD binding domain Methyltransf_29 PF03141.11 EIE89524.1 - 0.14 10.4 4.3 0.22 9.8 3.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase COG5 PF10392.4 EIE89524.1 - 0.2 11.6 8.2 0.029 14.3 0.9 2.9 3 0 0 3 3 3 0 Golgi transport complex subunit 5 ABC2_membrane_3 PF12698.2 EIE89524.1 - 0.2 10.6 1.2 0.39 9.6 0.8 1.5 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF4211 PF13926.1 EIE89525.1 - 0.046 13.1 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4211) DUF1822 PF08852.6 EIE89525.1 - 0.13 11.1 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1822) BCDHK_Adom3 PF10436.4 EIE89527.1 - 1.9e-37 128.3 0.0 3e-37 127.6 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EIE89527.1 - 2.6e-19 68.9 0.0 9.3e-19 67.1 0.0 2.0 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EIE89527.1 - 4.1e-05 23.2 0.0 9.5e-05 22.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.1 EIE89527.1 - 0.018 14.7 0.0 0.059 13.0 0.0 1.9 1 1 0 1 1 1 0 GHKL domain HATPase_c_2 PF13581.1 EIE89527.1 - 0.025 14.3 0.0 4.6 7.0 0.0 2.3 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain ABC_tran PF00005.22 EIE89528.1 - 2.4e-47 160.6 0.0 5.9e-23 81.6 0.0 3.3 3 1 0 3 3 2 2 ABC transporter ABC_tran_2 PF12848.2 EIE89528.1 - 8.3e-23 80.0 4.4 8.3e-23 80.0 3.1 2.7 2 0 0 2 2 1 1 ABC transporter AAA_21 PF13304.1 EIE89528.1 - 8.6e-15 55.4 9.7 0.013 15.4 0.0 4.9 5 1 0 6 6 4 4 AAA domain SMC_N PF02463.14 EIE89528.1 - 4.5e-11 42.3 4.7 0.0032 16.7 0.0 4.4 4 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EIE89528.1 - 1.6e-07 30.7 0.0 0.013 15.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain Miro PF08477.8 EIE89528.1 - 1.9e-07 31.5 0.0 0.0099 16.3 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_17 PF13207.1 EIE89528.1 - 2.9e-07 31.3 7.0 0.0048 17.6 0.0 4.5 5 2 0 5 5 3 2 AAA domain AAA_22 PF13401.1 EIE89528.1 - 5e-07 29.9 0.1 0.026 14.6 0.0 3.5 4 1 0 4 4 3 2 AAA domain DUF258 PF03193.11 EIE89528.1 - 2.7e-06 26.6 0.0 0.019 14.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EIE89528.1 - 2.8e-06 27.2 0.0 0.07 13.0 0.0 3.1 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_28 PF13521.1 EIE89528.1 - 3.9e-06 26.9 0.0 0.15 12.0 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 EIE89528.1 - 5.1e-06 26.1 0.1 0.055 12.8 0.0 2.7 3 0 0 3 3 2 2 AAA-like domain AAA_16 PF13191.1 EIE89528.1 - 9.9e-06 25.6 0.0 0.096 12.6 0.0 3.0 2 0 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.1 EIE89528.1 - 1.8e-05 24.6 0.2 0.26 11.1 0.0 3.1 3 0 0 3 3 3 2 AAA domain MobB PF03205.9 EIE89528.1 - 2e-05 24.3 0.1 0.22 11.2 0.0 2.9 3 0 0 3 3 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 EIE89528.1 - 2.1e-05 24.8 3.0 0.19 12.0 0.0 4.5 4 1 0 4 4 3 2 AAA domain AAA_23 PF13476.1 EIE89528.1 - 8.3e-05 23.0 30.9 0.024 14.9 0.0 5.2 4 1 1 5 5 5 2 AAA domain AAA_14 PF13173.1 EIE89528.1 - 9.9e-05 22.2 1.5 0.93 9.4 0.0 3.7 4 0 0 4 4 3 2 AAA domain NACHT PF05729.7 EIE89528.1 - 0.00011 21.8 0.1 0.24 11.0 0.0 2.9 3 0 0 3 3 2 2 NACHT domain AAA_25 PF13481.1 EIE89528.1 - 0.00016 21.1 0.0 0.21 11.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 EIE89528.1 - 0.00041 20.5 1.2 1.9 8.7 0.1 3.8 2 2 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) ArgK PF03308.11 EIE89528.1 - 0.0011 17.8 0.1 0.99 8.1 0.0 2.5 2 0 0 2 2 2 2 ArgK protein RNA_helicase PF00910.17 EIE89528.1 - 0.0014 18.7 0.0 2.6 8.2 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_30 PF13604.1 EIE89528.1 - 0.0022 17.6 0.0 0.21 11.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 EIE89528.1 - 0.003 17.0 0.0 0.41 10.0 0.0 2.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family SbcCD_C PF13558.1 EIE89528.1 - 0.0047 16.8 0.2 0.096 12.6 0.0 3.0 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Septin PF00735.13 EIE89528.1 - 0.0073 15.3 0.0 1.5 7.8 0.0 2.5 2 0 0 2 2 2 1 Septin AAA_24 PF13479.1 EIE89528.1 - 0.0081 15.7 0.1 5.6 6.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EIE89528.1 - 0.0097 15.0 0.5 0.65 9.0 0.0 3.1 3 0 0 3 3 3 1 Zeta toxin Dynamin_N PF00350.18 EIE89528.1 - 0.0099 15.7 10.7 0.32 10.8 0.0 4.2 3 1 0 4 4 4 2 Dynamin family NB-ARC PF00931.17 EIE89528.1 - 0.016 14.0 0.2 0.72 8.6 0.0 2.6 2 1 0 2 2 2 0 NB-ARC domain cobW PF02492.14 EIE89528.1 - 0.022 14.2 1.0 2.3 7.6 0.0 2.7 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PIN PF01850.16 EIE89528.1 - 0.024 14.9 0.3 0.25 11.6 0.0 2.6 2 0 0 2 2 2 0 PIN domain NTPase_1 PF03266.10 EIE89528.1 - 0.026 14.2 0.1 11 5.7 0.0 2.7 2 0 0 2 2 2 0 NTPase GBP_repeat PF02526.9 EIE89528.1 - 0.072 12.4 0.3 0.85 9.0 0.0 2.5 2 0 0 2 2 2 0 Glycophorin-binding protein PduV-EutP PF10662.4 EIE89528.1 - 0.074 12.5 0.0 16 5.0 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATP-synt_ab PF00006.20 EIE89528.1 - 0.11 11.9 0.0 0.78 9.1 0.0 2.1 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain ATP_bind_1 PF03029.12 EIE89528.1 - 0.13 11.7 2.1 3.5 7.1 0.0 2.9 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein SRP54 PF00448.17 EIE89528.1 - 0.16 11.3 1.7 11 5.4 0.0 3.3 3 1 1 4 4 4 0 SRP54-type protein, GTPase domain DUF87 PF01935.12 EIE89528.1 - 0.2 11.4 0.0 0.2 11.4 0.0 4.5 3 1 2 5 5 4 0 Domain of unknown function DUF87 Ribosomal_S19e PF01090.14 EIE89529.1 - 3.1e-61 204.8 0.2 3.5e-61 204.7 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e CWC25 PF12542.3 EIE89530.1 - 0.19 12.1 4.6 0.41 11.1 3.2 1.6 1 0 0 1 1 1 0 Pre-mRNA splicing factor Es2 PF09751.4 EIE89531.1 - 5.4e-65 220.4 6.4 1e-49 170.0 1.6 2.2 1 1 1 2 2 2 2 Nuclear protein Es2 GST_C_2 PF13410.1 EIE89532.1 - 4.4e-10 39.3 0.0 6.3e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EIE89532.1 - 2.9e-09 36.7 0.0 8.9e-09 35.2 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EIE89532.1 - 6.4e-06 26.5 0.0 8.4e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EIE89532.1 - 5.1e-05 23.4 0.0 0.00024 21.2 0.0 2.0 1 1 1 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIE89532.1 - 0.00065 19.6 0.0 0.0038 17.2 0.0 1.9 1 1 1 2 2 2 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 EIE89532.1 - 0.045 13.7 0.1 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 Glutaredoxin GST_N PF02798.15 EIE89532.1 - 0.088 12.9 0.1 0.73 10.0 0.0 2.3 2 1 1 3 3 3 0 Glutathione S-transferase, N-terminal domain Mito_carr PF00153.22 EIE89533.1 - 5.9e-54 179.7 2.3 3.9e-24 84.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF787 PF05619.6 EIE89533.1 - 0.16 10.5 0.0 0.25 9.9 0.0 1.2 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF787) WD40 PF00400.27 EIE89534.1 - 4e-51 169.1 14.9 1.8e-09 37.0 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EIE89534.1 - 0.037 12.7 0.0 1.5 7.5 0.0 2.6 2 1 1 3 3 3 0 Nup133 N terminal like Nup160 PF11715.3 EIE89534.1 - 0.039 12.0 3.1 2 6.4 0.1 4.0 2 1 3 5 5 5 0 Nucleoporin Nup120/160 BNR PF02012.15 EIE89536.1 - 5.2e-06 25.4 9.0 9.4 6.5 0.0 6.7 6 0 0 6 6 6 3 BNR/Asp-box repeat Reg_prop PF07494.6 EIE89536.1 - 0.047 13.7 0.3 71 3.9 0.1 4.6 3 0 0 3 3 3 0 Two component regulator propeller Sulfate_transp PF00916.15 EIE89537.1 - 3e-66 223.2 11.1 7.5e-41 139.9 1.4 2.3 2 0 0 2 2 2 2 Sulfate transporter family STAS PF01740.16 EIE89537.1 - 3.9e-10 39.1 0.0 8.4e-10 38.0 0.0 1.5 1 0 0 1 1 1 1 STAS domain SpoIIIAC PF06686.6 EIE89537.1 - 0.0061 16.3 0.3 0.0061 16.3 0.2 2.6 2 0 0 2 2 2 1 Stage III sporulation protein AC/AD protein family SOG2 PF10428.4 EIE89540.1 - 2.8e-30 105.3 6.2 2.2e-17 62.8 0.4 2.1 1 1 1 2 2 2 2 RAM signalling pathway protein DUF892 PF05974.7 EIE89540.1 - 0.0054 16.5 0.5 0.069 12.9 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF892) FAD_binding_1 PF00667.15 EIE89541.1 - 2.1e-56 190.8 0.1 3.5e-56 190.0 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EIE89541.1 - 2.3e-34 118.4 0.3 5.2e-34 117.2 0.2 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 EIE89541.1 - 2.2e-21 76.4 0.0 1.5e-20 73.7 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain CbiG_N PF11760.3 EIE89541.1 - 0.18 11.5 0.0 0.41 10.3 0.0 1.5 1 0 0 1 1 1 0 Cobalamin synthesis G N-terminal ING PF12998.2 EIE89542.1 - 6.6e-08 32.7 3.9 7e-08 32.6 0.1 2.0 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 EIE89542.1 - 1.6e-06 27.7 2.6 3.1e-06 26.7 1.8 1.4 1 0 0 1 1 1 1 PHD-finger zf-RING-like PF08746.6 EIE89542.1 - 0.074 13.0 2.9 0.17 11.8 2.0 1.6 1 0 0 1 1 1 0 RING-like domain zf-HC5HC2H PF13771.1 EIE89542.1 - 0.078 13.1 2.5 0.21 11.7 1.7 1.9 1 1 0 1 1 1 0 PHD-like zinc-binding domain DUF2962 PF11176.3 EIE89542.1 - 0.54 9.8 0.0 0.54 9.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2962) Ferritin PF00210.19 EIE89543.1 - 5.9e-44 149.2 0.9 6.9e-44 149.0 0.7 1.0 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.12 EIE89543.1 - 1.7e-06 28.4 0.1 2.2e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Rubrerythrin DUF4185 PF13810.1 EIE89543.1 - 0.046 12.6 0.2 0.063 12.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4185) Septum_form PF13845.1 EIE89543.1 - 0.074 12.5 0.3 0.3 10.5 0.0 1.9 1 1 1 2 2 2 0 Septum formation DUF779 PF05610.6 EIE89543.1 - 0.11 12.4 0.0 0.32 11.0 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF779) Zds_C PF08632.5 EIE89544.1 - 5.3e-21 73.7 1.6 1.1e-20 72.6 1.1 1.5 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Aminotran_1_2 PF00155.16 EIE89545.1 - 1.1e-35 123.3 0.0 1.2e-35 123.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II ASFV_p27 PF06556.6 EIE89545.1 - 0.063 13.1 0.0 7.1 6.5 0.0 2.3 2 0 0 2 2 2 0 IAP-like protein p27 C-terminus MOZ_SAS PF01853.13 EIE89546.1 - 2.1e-89 297.7 0.5 3.3e-89 297.1 0.3 1.3 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 EIE89546.1 - 3.8e-20 71.3 0.4 1e-19 69.9 0.0 1.9 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain HTH_11 PF08279.7 EIE89546.1 - 0.0057 16.2 0.6 0.012 15.1 0.4 1.5 1 0 0 1 1 1 1 HTH domain HTH_IclR PF09339.5 EIE89546.1 - 0.077 12.5 0.1 0.37 10.4 0.1 2.1 2 0 0 2 2 2 0 IclR helix-turn-helix domain PHD PF00628.24 EIE89547.1 - 4.4e-07 29.4 9.4 4.4e-07 29.4 6.5 1.8 2 1 0 2 2 2 1 PHD-finger NAD_binding_1 PF00175.16 EIE89547.1 - 0.12 12.9 0.0 0.27 11.8 0.0 1.6 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain DUF2399 PF09664.5 EIE89547.1 - 0.14 12.0 1.0 0.24 11.2 0.1 1.8 2 1 0 2 2 2 0 Protein of unknown function C-terminus (DUF2399) PHD_2 PF13831.1 EIE89547.1 - 1.1 8.6 13.1 0.29 10.4 5.9 2.5 2 1 0 2 2 2 0 PHD-finger C1_1 PF00130.17 EIE89547.1 - 4.5 7.0 8.5 0.34 10.6 0.9 2.4 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) RRS1 PF04939.7 EIE89548.1 - 1.1e-13 50.9 6.4 1.1e-13 50.9 4.4 1.9 2 0 0 2 2 2 1 Ribosome biogenesis regulatory protein (RRS1) DUF2829 PF11195.3 EIE89548.1 - 0.97 9.9 4.1 2.5 8.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2829) DUF4407 PF14362.1 EIE89548.1 - 2 7.3 6.4 1.8 7.4 4.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) LRR_9 PF14580.1 EIE89549.1 - 3e-07 30.1 0.0 5e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.2 EIE89549.1 - 4.6e-07 29.3 9.0 2.4e-05 23.8 2.1 2.6 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EIE89549.1 - 7.9e-05 22.3 1.3 0.00079 19.1 0.2 2.3 1 1 1 2 2 2 2 Leucine rich repeat Tap-RNA_bind PF09162.5 EIE89549.1 - 0.0011 18.5 0.0 0.0038 16.7 0.0 1.9 2 0 0 2 2 2 1 Tap, RNA-binding NTF2 PF02136.15 EIE89549.1 - 0.0019 18.5 0.0 0.0049 17.2 0.0 1.8 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain LRR_6 PF13516.1 EIE89549.1 - 0.014 15.3 2.9 7.7 6.9 0.1 3.8 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.28 EIE89549.1 - 0.023 14.6 0.5 3.4 8.0 0.0 3.5 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_7 PF13504.1 EIE89549.1 - 0.061 13.5 2.0 29 5.4 0.1 3.6 3 0 0 3 3 3 0 Leucine rich repeat CBFB_NFYA PF02045.10 EIE89550.1 - 2.8e-11 43.7 0.6 2.8e-11 43.7 0.4 1.8 2 0 0 2 2 2 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Ribosomal_L35Ae PF01247.13 EIE89551.1 - 5.8e-42 141.3 1.7 6.5e-42 141.2 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 EIE89551.1 - 0.0029 17.5 0.1 0.33 10.8 0.0 2.1 2 0 0 2 2 2 2 RimM N-terminal domain EamA PF00892.15 EIE89552.1 - 9.5e-05 22.4 23.7 0.00016 21.7 2.6 2.6 2 1 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.10 EIE89552.1 - 0.0018 17.4 6.4 0.0041 16.2 4.4 1.8 1 1 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.11 EIE89552.1 - 0.015 14.9 15.3 0.48 10.0 6.3 2.4 2 1 0 2 2 2 0 Triose-phosphate Transporter family UAA PF08449.6 EIE89552.1 - 0.11 11.4 12.3 0.99 8.2 8.5 2.0 1 1 0 1 1 1 0 UAA transporter family MerC PF03203.9 EIE89552.1 - 0.32 11.3 5.7 2.1 8.7 4.0 2.5 1 1 0 1 1 1 0 MerC mercury resistance protein EmrE PF13536.1 EIE89552.1 - 4.2 7.5 22.7 0.038 14.1 1.5 2.8 2 1 1 3 3 3 0 Multidrug resistance efflux transporter Ribosomal_L18e PF00828.14 EIE89554.1 - 3.9e-24 85.4 0.1 3.9e-24 85.4 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 eIF-3c_N PF05470.7 EIE89555.1 - 0.0084 14.2 0.0 0.0086 14.2 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus BSP_II PF05432.6 EIE89555.1 - 0.064 12.5 13.2 0.099 11.9 9.1 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) CENP-B_dimeris PF09026.5 EIE89555.1 - 0.088 13.0 7.6 0.2 11.9 5.2 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Pox_Ag35 PF03286.9 EIE89555.1 - 0.74 9.3 5.0 1.5 8.2 3.5 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Nop14 PF04147.7 EIE89555.1 - 1.3 6.8 10.1 2 6.2 7.0 1.2 1 0 0 1 1 1 0 Nop14-like family VID27 PF08553.5 EIE89555.1 - 2.5 6.2 12.7 3.8 5.6 8.8 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Sporozoite_P67 PF05642.6 EIE89555.1 - 3.1 5.5 5.8 4.5 5.0 4.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Daxx PF03344.10 EIE89555.1 - 7.8 4.8 10.9 12 4.2 7.6 1.2 1 0 0 1 1 1 0 Daxx Family Kelch_1 PF01344.20 EIE89556.1 - 2e-12 46.4 5.1 0.00049 19.5 0.4 4.3 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.1 EIE89556.1 - 4.5e-11 42.3 2.4 0.0027 17.4 0.0 4.8 4 1 0 4 4 4 3 Galactose oxidase, central domain Kelch_6 PF13964.1 EIE89556.1 - 4.1e-10 39.4 2.0 0.0044 17.1 0.1 4.3 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.1 EIE89556.1 - 2.6e-09 36.9 3.1 0.0046 17.0 0.0 4.5 4 1 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.10 EIE89556.1 - 5.9e-07 28.9 4.9 0.28 10.9 0.4 4.7 4 1 0 4 4 4 3 Kelch motif Kelch_5 PF13854.1 EIE89556.1 - 6.2e-07 29.2 1.1 0.003 17.4 0.2 3.5 3 0 0 3 3 3 2 Kelch motif RAG2 PF03089.9 EIE89556.1 - 0.01 14.5 0.1 0.059 12.0 0.0 1.8 1 1 1 2 2 2 0 Recombination activating protein 2 Ribosomal_L18p PF00861.17 EIE89559.1 - 2.9e-44 150.0 0.0 6e-44 149.0 0.0 1.5 1 0 0 1 1 1 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 EIE89559.1 - 2.5e-30 104.8 2.8 2.5e-30 104.8 2.0 1.7 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region O-FucT PF10250.4 EIE89560.1 - 9.6e-14 51.2 1.1 7.5e-06 25.2 0.3 3.5 2 1 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase RLAN PF14401.1 EIE89560.1 - 0.0036 16.8 0.0 0.0061 16.0 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATPgrasp N-terminal domain FYRC PF05965.9 EIE89561.1 - 6.9e-19 67.4 0.0 1.6e-18 66.2 0.0 1.7 1 0 0 1 1 1 1 F/Y rich C-terminus FYRN PF05964.9 EIE89561.1 - 1.8e-17 62.5 0.0 5.1e-17 61.0 0.0 1.8 1 0 0 1 1 1 1 F/Y-rich N-terminus DUF2540 PF10802.3 EIE89561.1 - 0.47 10.1 4.3 2.9 7.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2540) V_ATPase_I PF01496.14 EIE89561.1 - 0.76 7.5 3.7 1.2 6.8 2.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PAS_9 PF13426.1 EIE89562.1 - 8.9e-30 103.1 0.0 1e-15 57.9 0.0 3.8 3 1 0 3 3 3 3 PAS domain PAS_3 PF08447.6 EIE89562.1 - 3.5e-23 81.5 0.0 5.3e-14 52.0 0.0 3.8 3 0 0 3 3 3 3 PAS fold GATA PF00320.22 EIE89562.1 - 8.1e-16 57.0 2.9 2e-15 55.8 2.0 1.7 1 0 0 1 1 1 1 GATA zinc finger PAS_11 PF14598.1 EIE89562.1 - 1.1e-12 47.8 0.1 1.9e-08 34.2 0.0 3.1 3 1 0 3 3 3 2 PAS domain PAS PF00989.19 EIE89562.1 - 1.6e-11 43.9 0.0 8.6e-06 25.5 0.0 3.5 3 0 0 3 3 3 2 PAS fold PAS_4 PF08448.5 EIE89562.1 - 3.3e-10 39.9 0.0 0.0067 16.4 0.0 3.4 3 0 0 3 3 3 3 PAS fold KilA-N PF04383.8 EIE89563.1 - 8.4e-05 22.1 0.5 0.00024 20.7 0.0 1.9 2 0 0 2 2 2 1 KilA-N domain Med15 PF09606.5 EIE89563.1 - 0.00097 17.4 10.9 0.00097 17.4 7.5 1.0 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Spt20 PF12090.3 EIE89563.1 - 0.0015 17.8 3.0 0.0017 17.7 2.1 1.2 1 0 0 1 1 1 1 Spt20 family DUF940 PF06082.6 EIE89563.1 - 0.0018 16.9 0.7 0.002 16.7 0.5 1.0 1 0 0 1 1 1 1 Bacterial putative lipoprotein (DUF940) DUF2201_N PF13203.1 EIE89563.1 - 0.015 14.4 3.1 0.019 14.1 2.1 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Anp1 PF03452.9 EIE89563.1 - 0.024 13.8 0.5 0.026 13.7 0.3 1.1 1 0 0 1 1 1 0 Anp1 Folate_carrier PF01770.13 EIE89563.1 - 0.071 11.6 1.9 0.092 11.2 1.3 1.0 1 0 0 1 1 1 0 Reduced folate carrier FimP PF09766.4 EIE89563.1 - 0.11 11.4 7.6 0.14 11.1 5.3 1.1 1 0 0 1 1 1 0 Fms-interacting protein RAB3GAP2_N PF14655.1 EIE89563.1 - 0.13 11.2 3.8 0.15 10.9 2.7 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Serinc PF03348.10 EIE89563.1 - 0.14 10.8 2.5 0.15 10.6 1.8 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Suf PF05843.9 EIE89563.1 - 0.23 11.1 5.8 0.27 10.9 4.0 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) BAF1_ABF1 PF04684.8 EIE89563.1 - 0.32 9.7 10.8 0.36 9.6 7.5 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor PHD_3 PF13922.1 EIE89563.1 - 0.38 11.0 5.0 0.83 9.9 3.5 1.7 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx DUF4175 PF13779.1 EIE89563.1 - 1.1 6.8 15.2 1.3 6.5 10.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF788 PF05620.6 EIE89563.1 - 2.3 8.0 5.5 3.4 7.5 3.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF788) DivIC PF04977.10 EIE89563.1 - 4.4 6.8 11.2 8.2 6.0 7.7 1.4 1 0 0 1 1 1 0 Septum formation initiator DUF2967 PF11179.3 EIE89563.1 - 5.4 6.4 12.8 10 5.5 8.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) OrfB_Zn_ribbon PF07282.6 EIE89564.1 - 0.04 13.5 0.6 0.045 13.4 0.4 1.3 1 1 0 1 1 1 0 Putative transposase DNA-binding domain Ribosomal_L17 PF01196.14 EIE89565.1 - 1.1e-35 122.0 0.4 3e-35 120.6 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L17 5_3_exonuc PF01367.15 EIE89565.1 - 0.047 13.9 1.1 0.1 12.8 0.4 1.8 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold GCV_T PF01571.16 EIE89566.1 - 2.9e-10 39.8 0.0 4.1e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EIE89566.1 - 4.3e-06 26.6 0.0 8.6e-06 25.7 0.0 1.5 1 1 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain FYVE PF01363.16 EIE89567.1 - 9.5e-17 60.6 8.5 2.8e-16 59.1 5.9 1.8 1 0 0 1 1 1 1 FYVE zinc finger zf-AN1 PF01428.11 EIE89567.1 - 0.021 14.7 10.0 0.021 14.7 6.9 2.6 2 0 0 2 2 2 0 AN1-like Zinc finger HEAT_EZ PF13513.1 EIE89568.1 - 6.3e-19 67.8 0.6 7.3e-08 32.6 0.0 7.5 7 1 1 8 8 8 3 HEAT-like repeat HEAT PF02985.17 EIE89568.1 - 1.2e-18 65.3 7.8 0.00037 20.3 0.0 7.6 7 0 0 7 7 7 4 HEAT repeat HEAT_2 PF13646.1 EIE89568.1 - 4.8e-16 58.8 0.1 0.00053 20.2 0.0 5.1 4 1 0 4 4 4 4 HEAT repeats Vac14_Fab1_bd PF12755.2 EIE89568.1 - 9.6e-11 41.9 0.9 0.67 10.3 0.0 5.5 4 1 1 5 5 5 4 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 EIE89568.1 - 3.4e-05 23.3 0.6 0.56 9.5 0.0 3.9 4 2 1 5 5 5 2 CLASP N terminal Cnd1 PF12717.2 EIE89568.1 - 0.00021 21.2 2.2 0.33 10.7 0.3 4.3 3 2 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 DUF2435 PF10363.4 EIE89568.1 - 0.00089 19.1 0.2 2.1 8.2 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF2435) Arm PF00514.18 EIE89568.1 - 1.3 8.9 6.8 11 6.0 0.0 4.8 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat DUF4179 PF13786.1 EIE89569.1 - 0.14 12.4 1.6 4.2 7.6 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) CAF-1_p150 PF11600.3 EIE89569.1 - 9.5 5.5 21.1 16 4.7 14.7 1.4 1 1 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Iron_permease PF04120.7 EIE89570.1 - 7.5 6.1 7.9 21 4.6 5.5 1.8 1 0 0 1 1 1 0 Low affinity iron permease PDH PF02153.12 EIE89571.1 - 1.8e-16 59.8 0.1 2.4e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.12 EIE89571.1 - 6.6e-06 26.4 0.0 1.3e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 EIE89571.1 - 0.006 16.4 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 EIE89571.1 - 0.0064 16.5 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 EIE89571.1 - 0.011 15.1 0.0 0.024 14.0 0.0 1.6 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 EIE89571.1 - 0.019 14.6 0.0 0.069 12.8 0.0 1.9 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.16 EIE89571.1 - 0.048 13.4 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 ThiF family Reprolysin_4 PF13583.1 EIE89572.1 - 7.2e-36 123.6 1.5 1.4e-35 122.7 1.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EIE89572.1 - 7.4e-36 123.9 6.9 7.4e-36 123.9 4.8 2.0 2 1 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 EIE89572.1 - 4.8e-27 95.1 3.0 4.8e-27 95.1 2.1 1.8 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 EIE89572.1 - 7.3e-20 71.7 0.4 7.3e-20 71.7 0.3 2.7 3 0 0 3 3 3 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.18 EIE89572.1 - 6.3e-18 64.7 23.5 6.3e-18 64.7 16.3 4.5 4 1 1 5 5 5 1 Disintegrin Reprolysin PF01421.14 EIE89572.1 - 8.2e-07 28.7 4.0 3.8e-06 26.6 2.8 2.0 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease DUF4043 PF13252.1 EIE89572.1 - 0.0024 16.8 0.1 0.0064 15.5 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4043) MIS13 PF08202.6 EIE89573.1 - 4.8e-19 68.5 28.3 8.9e-19 67.6 6.9 2.4 1 1 1 2 2 2 2 Mis12-Mtw1 protein family Peptidase_M15 PF01427.12 EIE89573.1 - 0.0017 17.9 0.6 0.0034 16.9 0.4 1.5 1 0 0 1 1 1 1 D-ala-D-ala dipeptidase zf-CCCH PF00642.19 EIE89574.1 - 7.6e-12 44.6 8.9 1.8e-08 33.8 1.9 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EIE89574.1 - 0.00086 19.2 3.4 0.75 9.8 0.6 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type ABC_tran PF00005.22 EIE89575.1 - 2.8e-30 105.4 1.9 6e-29 101.0 0.0 2.6 2 0 0 2 2 2 1 ABC transporter AAA_22 PF13401.1 EIE89575.1 - 7.1e-06 26.1 1.2 6.1e-05 23.1 0.1 2.9 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EIE89575.1 - 7.5e-06 26.0 0.0 1.8e-05 24.8 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 EIE89575.1 - 9.9e-06 25.4 5.6 0.0011 18.9 0.0 3.8 2 1 2 4 4 4 1 AAA domain AAA_17 PF13207.1 EIE89575.1 - 1.6e-05 25.7 0.0 0.00015 22.5 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_29 PF13555.1 EIE89575.1 - 0.00017 21.0 0.0 0.00043 19.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.1 EIE89575.1 - 0.00028 21.1 3.9 0.00033 20.9 0.0 2.9 4 0 0 4 4 2 1 AAA domain ATP-synt_ab PF00006.20 EIE89575.1 - 0.00045 19.7 0.7 0.00099 18.6 0.0 1.9 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 EIE89575.1 - 0.00074 19.0 0.0 0.0016 17.9 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA PF00004.24 EIE89575.1 - 0.00085 19.5 0.8 0.011 15.9 0.0 2.8 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EIE89575.1 - 0.0019 18.3 0.1 0.014 15.5 0.0 2.5 2 0 0 2 2 2 1 RNA helicase DUF258 PF03193.11 EIE89575.1 - 0.0046 16.1 0.0 0.011 14.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_5 PF07728.9 EIE89575.1 - 0.0047 16.6 0.6 0.069 12.8 0.0 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.18 EIE89575.1 - 0.0048 16.8 0.7 0.13 12.2 0.0 3.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_30 PF13604.1 EIE89575.1 - 0.0066 16.0 0.0 0.02 14.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EIE89575.1 - 0.0073 16.1 0.3 0.031 14.1 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EIE89575.1 - 0.013 14.9 0.1 0.052 12.9 0.0 2.0 1 1 0 1 1 1 0 AAA-like domain NTPase_1 PF03266.10 EIE89575.1 - 0.013 15.2 0.1 0.3 10.7 0.0 2.5 1 1 1 2 2 2 0 NTPase AAA_19 PF13245.1 EIE89575.1 - 0.02 14.6 0.0 0.057 13.1 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_25 PF13481.1 EIE89575.1 - 0.025 14.0 0.0 0.05 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 EIE89575.1 - 0.038 12.7 0.0 0.078 11.7 0.0 1.4 1 0 0 1 1 1 0 ArgK protein Fer4_NifH PF00142.13 EIE89575.1 - 0.058 12.5 0.9 0.63 9.1 0.0 2.2 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_23 PF13476.1 EIE89575.1 - 0.16 12.2 10.4 0.54 10.5 7.2 1.9 1 1 0 1 1 1 0 AAA domain Ribosomal_S9 PF00380.14 EIE89575.1 - 0.26 11.5 2.0 0.74 10.0 1.0 2.1 1 1 1 2 2 2 0 Ribosomal protein S9/S16 Paf67 PF10255.4 EIE89576.1 - 2e-156 520.9 10.1 2.9e-156 520.3 7.0 1.2 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.12 EIE89576.1 - 3e-05 23.5 0.2 0.00047 19.8 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EIE89576.1 - 0.0003 20.2 0.7 0.0017 17.8 0.0 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF2042 PF09743.4 EIE89576.1 - 0.00046 19.5 0.6 0.066 12.5 0.0 2.6 3 0 0 3 3 3 2 Uncharacterized conserved protein (DUF2042) TPR_12 PF13424.1 EIE89576.1 - 0.00079 19.3 0.8 0.044 13.7 0.1 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat PCI PF01399.22 EIE89576.1 - 0.013 15.7 0.1 0.049 13.9 0.0 1.9 1 0 0 1 1 1 0 PCI domain NTP_transf_2 PF01909.18 EIE89576.1 - 0.047 14.0 0.0 0.18 12.1 0.0 1.9 1 0 0 1 1 1 0 Nucleotidyltransferase domain TPR_11 PF13414.1 EIE89576.1 - 0.11 12.1 0.1 0.11 12.1 0.1 2.7 3 1 0 3 3 3 0 TPR repeat TPR_6 PF13174.1 EIE89576.1 - 0.12 12.8 1.0 16 6.1 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Ecl1 PF12855.2 EIE89577.1 - 0.00052 19.2 5.1 0.00052 19.2 3.5 2.2 2 0 0 2 2 2 1 Life-span regulatory factor DZR PF12773.2 EIE89577.1 - 0.14 12.0 1.6 0.17 11.7 0.6 1.5 2 0 0 2 2 2 0 Double zinc ribbon DUF581 PF04570.9 EIE89577.1 - 0.19 11.0 8.4 0.65 9.3 4.6 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF581) PLATZ PF04640.9 EIE89577.1 - 1.9 8.7 5.9 0.55 10.4 2.0 1.6 2 0 0 2 2 2 0 PLATZ transcription factor zf-UBP PF02148.14 EIE89577.1 - 7.5 6.7 6.6 1.1e+02 3.0 4.6 2.3 1 1 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein Adaptin_binding PF10199.4 EIE89578.1 - 9.3e-16 58.3 10.1 2e-15 57.2 7.0 1.6 1 0 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 SAD_SRA PF02182.12 EIE89579.1 - 2.2e-21 75.8 0.0 3.4e-21 75.1 0.0 1.3 1 0 0 1 1 1 1 SAD/SRA domain PHD PF00628.24 EIE89579.1 - 9.3e-05 22.0 13.3 9.3e-05 22.0 9.2 2.2 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.1 EIE89579.1 - 0.0002 20.5 3.2 0.0002 20.5 2.2 2.9 3 1 0 3 3 3 1 PHD-finger ubiquitin PF00240.18 EIE89579.1 - 0.00068 18.9 0.1 0.0018 17.5 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin family CsiD PF08943.5 EIE89579.1 - 0.0014 17.6 0.1 0.0023 16.8 0.1 1.3 1 0 0 1 1 1 1 CsiD Glucosamine_iso PF01182.15 EIE89580.1 - 2e-23 83.1 0.0 3.1e-23 82.5 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase TBCC PF07986.7 EIE89581.1 - 6.9e-27 93.2 1.3 1.3e-26 92.3 0.9 1.5 1 0 0 1 1 1 1 Tubulin binding cofactor C Osmo_CC PF08946.5 EIE89581.1 - 0.085 12.8 1.3 0.27 11.2 0.0 2.6 2 0 0 2 2 2 0 Osmosensory transporter coiled coil Exonuc_VII_L PF02601.10 EIE89581.1 - 0.33 10.0 7.1 0.59 9.2 4.9 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Bin3 PF06859.7 EIE89582.1 - 2.9e-32 110.8 0.0 4.7e-32 110.2 0.0 1.3 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_18 PF12847.2 EIE89582.1 - 2.1e-14 54.0 0.0 1.7e-13 51.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIE89582.1 - 3.8e-14 52.5 0.0 4.4e-09 36.1 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.1 EIE89582.1 - 1e-13 51.3 0.0 1.7e-13 50.6 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIE89582.1 - 1.3e-11 44.8 0.0 4e-07 30.4 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.7 EIE89582.1 - 4.7e-09 36.6 0.0 6.2e-05 23.4 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_26 PF13659.1 EIE89582.1 - 1.2e-07 31.7 0.0 2.9e-07 30.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EIE89582.1 - 1.6e-06 27.4 0.0 2.5e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 EIE89582.1 - 1.8e-06 27.1 0.0 2.1e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.9 EIE89582.1 - 3.9e-06 26.3 0.0 5.7e-05 22.5 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EIE89582.1 - 8.2e-06 26.1 0.0 4.7e-05 23.6 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Spermine_synth PF01564.12 EIE89582.1 - 2.8e-05 23.1 0.2 0.018 13.9 0.0 2.1 2 0 0 2 2 2 2 Spermine/spermidine synthase Methyltransf_PK PF05891.7 EIE89582.1 - 0.001 18.4 0.1 0.024 13.9 0.0 2.0 2 0 0 2 2 2 1 AdoMet dependent proline di-methyltransferase CMAS PF02353.15 EIE89582.1 - 0.0017 17.5 0.0 0.095 11.7 0.0 2.1 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase PCMT PF01135.14 EIE89582.1 - 0.0019 17.7 0.0 0.0054 16.2 0.0 1.6 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.13 EIE89582.1 - 0.0026 16.8 0.2 0.0086 15.2 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.1 EIE89582.1 - 0.0066 16.1 0.0 0.019 14.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain FmrO PF07091.6 EIE89582.1 - 0.037 13.0 0.0 0.069 12.1 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) RrnaAD PF00398.15 EIE89582.1 - 0.052 12.5 0.0 0.083 11.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_15 PF09445.5 EIE89582.1 - 0.11 11.9 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_9 PF08003.6 EIE89582.1 - 0.15 10.7 0.1 0.79 8.3 0.0 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1698) Peptidase_M22 PF00814.20 EIE89583.1 - 2.7e-67 227.0 0.0 3.3e-67 226.8 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family DUF3773 PF12608.3 EIE89583.1 - 0.08 12.9 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3773) DUF3591 PF12157.3 EIE89584.1 - 5.5e-172 572.2 0.0 1.1e-171 571.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) TBP-binding PF09247.6 EIE89584.1 - 1.3e-08 34.8 0.1 4.5e-08 33.1 0.1 2.0 1 0 0 1 1 1 1 TATA box-binding protein binding zf-CCHC_6 PF15288.1 EIE89584.1 - 1.2e-05 24.8 1.8 2.7e-05 23.7 1.2 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-ribbon_3 PF13248.1 EIE89584.1 - 0.37 10.0 0.7 0.63 9.3 0.5 1.4 1 0 0 1 1 1 0 zinc-ribbon domain zf-CCHC PF00098.18 EIE89584.1 - 0.85 9.6 3.3 1.6 8.8 2.3 1.5 1 0 0 1 1 1 0 Zinc knuckle UDG PF03167.14 EIE89585.1 - 6.3e-29 100.4 0.1 1e-28 99.7 0.0 1.4 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily JAB PF01398.16 EIE89586.1 - 1.2e-14 54.0 0.0 3.8e-14 52.3 0.0 1.9 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF3685 PF12452.3 EIE89586.1 - 0.5 9.4 2.7 9.4 5.3 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3685) Rep_fac-A_3 PF08661.6 EIE89587.1 - 0.03 14.2 0.0 0.058 13.3 0.0 1.4 1 0 0 1 1 1 0 Replication factor A protein 3 zf-C4pol PF14260.1 EIE89588.1 - 0.019 14.9 5.0 0.28 11.2 3.5 2.0 1 1 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta DZR PF12773.2 EIE89588.1 - 0.035 13.9 9.2 0.41 10.4 6.4 2.3 1 1 0 1 1 1 0 Double zinc ribbon zf-piccolo PF05715.8 EIE89588.1 - 0.26 11.3 3.2 1.2 9.2 0.9 2.2 2 0 0 2 2 2 0 Piccolo Zn-finger GFA PF04828.9 EIE89588.1 - 0.39 10.6 8.8 0.047 13.6 1.7 2.0 1 1 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zf-ribbon_3 PF13248.1 EIE89588.1 - 0.48 9.6 7.1 0.15 11.3 1.2 2.5 2 1 0 2 2 2 0 zinc-ribbon domain A2L_zn_ribbon PF08792.5 EIE89588.1 - 0.57 9.7 8.4 18 4.9 0.1 3.1 3 0 0 3 3 3 0 A2L zinc ribbon domain HypA PF01155.14 EIE89588.1 - 2 8.0 6.7 0.66 9.6 1.1 2.0 1 1 0 2 2 2 0 Hydrogenase expression/synthesis hypA family zinc_ribbon_2 PF13240.1 EIE89588.1 - 3.9 7.0 9.6 3.1 7.3 0.1 2.9 2 1 1 3 3 3 0 zinc-ribbon domain Spt4 PF06093.8 EIE89588.1 - 8 6.4 7.0 22 5.0 4.2 2.0 1 1 0 1 1 1 0 Spt4/RpoE2 zinc finger MutS_II PF05188.12 EIE89590.1 - 0.033 14.2 0.1 0.062 13.3 0.0 1.4 1 0 0 1 1 1 0 MutS domain II Dimerisation PF08100.6 EIE89590.1 - 0.15 11.8 0.4 0.59 10.0 0.0 2.1 2 0 0 2 2 2 0 Dimerisation domain AAA_12 PF13087.1 EIE89591.1 - 1.3e-16 60.6 0.2 2.8e-16 59.5 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EIE89591.1 - 2.7e-08 33.6 0.0 4.2e-07 29.7 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EIE89591.1 - 0.00035 20.2 0.1 0.00071 19.2 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain PhoH PF02562.11 EIE89591.1 - 0.0017 17.6 0.1 0.0042 16.3 0.1 1.6 1 0 0 1 1 1 1 PhoH-like protein AAA_30 PF13604.1 EIE89591.1 - 0.0021 17.6 0.1 0.0048 16.5 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EIE89591.1 - 0.0029 17.3 0.1 3 7.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EIE89591.1 - 0.015 14.7 0.1 0.034 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EIE89591.1 - 0.023 15.4 0.0 0.097 13.4 0.0 2.2 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EIE89591.1 - 0.054 13.8 0.8 1.3 9.2 0.0 3.5 4 0 0 4 4 4 0 AAA domain AAA_22 PF13401.1 EIE89591.1 - 0.056 13.5 0.1 0.36 10.9 0.0 2.4 3 0 0 3 3 2 0 AAA domain IstB_IS21 PF01695.12 EIE89591.1 - 0.056 12.8 0.1 0.24 10.8 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein FANCI_S2 PF14676.1 EIE89591.1 - 0.3 10.9 1.9 5.3 6.9 0.1 3.0 3 0 0 3 3 3 0 FANCI solenoid 2 LRR_4 PF12799.2 EIE89592.1 - 5.5e-23 80.1 37.2 1.6e-08 33.9 3.4 4.7 1 1 4 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EIE89592.1 - 1.8e-19 69.1 22.0 1.3e-09 37.6 3.5 3.4 1 1 3 4 4 4 4 Leucine rich repeat LRR_1 PF00560.28 EIE89592.1 - 1.8e-12 45.4 9.8 0.32 11.1 0.1 6.9 6 0 0 6 6 6 4 Leucine Rich Repeat LRR_7 PF13504.1 EIE89592.1 - 2.5e-08 32.7 16.5 0.53 10.7 0.2 6.7 7 0 0 7 7 7 4 Leucine rich repeat LRR_6 PF13516.1 EIE89592.1 - 2.6e-05 23.8 15.4 0.78 9.9 0.1 5.9 5 0 0 5 5 5 2 Leucine Rich repeat LRR_9 PF14580.1 EIE89592.1 - 0.046 13.2 1.1 0.2 11.2 0.1 2.0 1 1 1 2 2 2 0 Leucine-rich repeat RGS PF00615.14 EIE89596.1 - 2e-22 79.5 0.0 7e-22 77.7 0.0 2.0 1 1 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.16 EIE89596.1 - 9.9e-13 47.6 0.2 1.3e-07 31.2 0.0 2.9 2 1 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) VID27 PF08553.5 EIE89597.1 - 0.18 10.0 0.9 0.18 10.0 0.6 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein zf-RING_2 PF13639.1 EIE89598.1 - 1.8e-09 37.2 2.8 3.7e-09 36.2 1.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EIE89598.1 - 2.7e-05 23.7 0.3 5.2e-05 22.8 0.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EIE89598.1 - 7.2e-05 22.8 1.9 0.00018 21.5 1.3 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger PA PF02225.17 EIE89598.1 - 0.00012 21.7 0.0 0.00026 20.6 0.0 1.5 1 0 0 1 1 1 1 PA domain zf-C3HC4_2 PF13923.1 EIE89598.1 - 0.0005 20.0 2.7 0.0011 18.9 1.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIE89598.1 - 0.0019 17.8 2.1 0.0035 17.0 1.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Polysacc_synt_C PF14667.1 EIE89598.1 - 0.075 12.8 0.2 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain zf-C3HC4_3 PF13920.1 EIE89598.1 - 0.093 12.4 2.0 0.17 11.6 1.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 EIE89598.1 - 0.22 11.2 2.5 0.39 10.4 1.7 1.4 1 0 0 1 1 1 0 PHD-finger zf-Apc11 PF12861.2 EIE89598.1 - 0.35 10.7 3.7 1.6 8.6 2.5 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Pkinase PF00069.20 EIE89599.1 - 7.8e-60 202.2 0.0 1.1e-59 201.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE89599.1 - 6.9e-33 113.7 0.1 5.8e-30 104.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EIE89599.1 - 3.8e-06 26.0 0.0 2.2e-05 23.6 0.0 2.1 1 1 0 1 1 1 1 Kinase-like Glyco_transf_22 PF03901.12 EIE89600.1 - 7e-84 282.2 22.7 8.7e-84 281.9 15.7 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Tmemb_170 PF10190.4 EIE89600.1 - 1.6 8.7 12.7 0.36 10.9 2.0 3.4 2 2 1 4 4 4 0 Putative transmembrane protein 170 PDR_assoc PF08370.6 EIE89600.1 - 5.7 6.5 7.2 3.9 7.0 0.3 3.3 3 0 0 3 3 3 0 Plant PDR ABC transporter associated CNH PF00780.17 EIE89601.1 - 3.9e-47 160.9 0.0 2.5e-40 138.6 0.0 2.4 1 1 1 2 2 2 2 CNH domain RhoGEF PF00621.15 EIE89601.1 - 7.7e-38 130.1 2.1 7.7e-38 130.1 1.5 1.7 2 0 0 2 2 2 1 RhoGEF domain PH_5 PF15405.1 EIE89601.1 - 7.8e-23 80.9 0.0 2e-22 79.5 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain NDUF_B8 PF05821.6 EIE89602.1 - 9e-10 38.4 0.0 1.5e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Tetraspannin PF00335.15 EIE89603.1 - 0.028 13.6 7.6 0.052 12.8 5.2 1.6 1 1 0 1 1 1 0 Tetraspanin family DUF1129 PF06570.6 EIE89603.1 - 2.1 7.6 4.5 2.6 7.3 1.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Fasciclin PF02469.17 EIE89604.1 - 1.4e-79 264.3 0.3 1.2e-21 77.0 0.1 5.1 5 0 0 5 5 5 5 Fasciclin domain DUF211 PF02680.9 EIE89604.1 - 0.18 11.6 5.2 20 5.0 0.0 3.4 3 0 0 3 3 3 0 Uncharacterized ArCR, COG1888 Ras PF00071.17 EIE89605.1 - 2.1e-55 186.4 0.0 2.4e-55 186.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIE89605.1 - 8e-18 65.0 0.0 1.1e-17 64.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIE89605.1 - 1.3e-08 34.2 0.0 1.6e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EIE89605.1 - 0.0014 18.1 0.0 0.012 15.0 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Oxidored_FMN PF00724.15 EIE89608.1 - 1.2e-74 251.4 0.0 1.5e-74 251.0 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.12 EIE89608.1 - 0.0054 15.6 0.5 0.016 14.0 0.0 1.7 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) UNC-93 PF05978.11 EIE89608.1 - 0.067 12.6 0.2 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 Ion channel regulatory protein UNC-93 Glyco_transf_20 PF00982.16 EIE89609.1 - 6.6e-157 522.7 0.0 8.7e-157 522.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EIE89609.1 - 1.3e-58 197.6 0.0 2.2e-46 157.6 0.0 2.3 1 1 1 2 2 2 2 Trehalose-phosphatase Ribosomal_L27e PF01777.13 EIE89610.1 - 4.9e-36 122.7 6.1 4.9e-36 122.7 4.3 2.4 2 0 0 2 2 2 1 Ribosomal L27e protein family KOW PF00467.24 EIE89610.1 - 0.00013 21.4 1.2 0.00027 20.5 0.8 1.5 1 0 0 1 1 1 1 KOW motif RRM_1 PF00076.17 EIE89610.1 - 0.0022 17.5 0.3 0.0083 15.7 0.1 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DMP1 PF07263.6 EIE89610.1 - 1.4 7.5 8.9 1.8 7.1 6.2 1.1 1 0 0 1 1 1 0 Dentin matrix protein 1 (DMP1) p450 PF00067.17 EIE89611.1 - 5.1e-70 236.2 0.6 7e-70 235.8 0.4 1.1 1 0 0 1 1 1 1 Cytochrome P450 Hpt PF01627.18 EIE89615.1 - 1.4e-11 44.2 0.0 2.8e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 Hpt domain DUF1250 PF06855.7 EIE89615.1 - 0.064 12.7 0.4 12 5.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1250) PhoQ_Sensor PF08918.5 EIE89615.1 - 0.33 10.4 3.3 0.67 9.4 2.2 1.6 1 1 0 1 1 1 0 PhoQ Sensor TUSC2 PF15000.1 EIE89615.1 - 0.78 9.8 5.2 0.33 11.0 2.0 1.6 2 0 0 2 2 2 0 Tumour suppressor candidate 2 GPI-anchored PF10342.4 EIE89616.1 - 7.9e-15 55.1 2.9 7.9e-15 55.1 2.0 2.6 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family TP_methylase PF00590.15 EIE89616.1 - 3.4 7.3 7.6 1 9.0 3.1 1.8 1 1 1 2 2 2 0 Tetrapyrrole (Corrin/Porphyrin) Methylases Macoilin PF09726.4 EIE89616.1 - 5.2 5.2 17.2 5.8 5.0 12.0 1.1 1 0 0 1 1 1 0 Transmembrane protein MBOAT PF03062.14 EIE89617.1 - 7.6e-28 97.5 17.7 1.3e-18 67.1 5.9 2.6 1 1 1 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family Spt5-NGN PF03439.8 EIE89618.1 - 7.1e-20 70.5 0.0 1.5e-19 69.5 0.0 1.5 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.24 EIE89618.1 - 8.5e-17 60.1 32.3 2.3e-06 27.1 0.2 7.5 7 1 0 7 7 7 4 KOW motif CTD PF12815.2 EIE89618.1 - 4.9e-12 46.3 37.1 1.3e-10 41.7 25.1 2.7 1 1 1 2 2 2 2 Spt5 C-terminal nonapeptide repeat binding Spt4 Spt5_N PF11942.3 EIE89618.1 - 1.2e-06 29.0 11.9 1.2e-06 29.0 8.3 3.0 3 0 0 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal SPT6_acidic PF14632.1 EIE89618.1 - 2.4 8.3 31.1 0.37 10.9 10.9 2.7 2 0 0 2 2 2 0 Acidic N-terminal SPT6 YajC PF02699.10 EIE89618.1 - 3.9 7.2 5.5 6.9 6.4 0.2 3.5 3 1 1 4 4 4 0 Preprotein translocase subunit Aldo_ket_red PF00248.16 EIE89619.1 - 2.7e-12 46.1 0.0 1.4e-05 24.0 0.0 2.0 2 0 0 2 2 2 2 Aldo/keto reductase family HAMP PF00672.20 EIE89620.1 - 7.5e-99 323.9 39.1 2e-08 34.3 0.2 13.9 13 0 0 13 13 13 12 HAMP domain HATPase_c PF02518.21 EIE89620.1 - 1.2e-30 105.4 0.1 6e-30 103.2 0.1 2.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EIE89620.1 - 7.5e-24 83.8 0.4 5.4e-23 81.1 0.0 2.6 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 EIE89620.1 - 6.6e-19 67.6 1.4 6.3e-18 64.5 0.4 3.4 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain HTH_6 PF01418.12 EIE89620.1 - 1.1e-06 28.2 7.4 28 4.5 0.0 10.1 11 0 0 11 11 11 0 Helix-turn-helix domain, rpiR family Pox_A_type_inc PF04508.7 EIE89620.1 - 0.00046 19.7 1.7 0.14 12.0 0.0 5.3 6 0 0 6 6 6 1 Viral A-type inclusion protein repeat HMG_box PF00505.14 EIE89620.1 - 0.00056 20.1 0.0 32 4.8 0.0 5.2 5 0 0 5 5 5 0 HMG (high mobility group) box RNA_pol_Rpb2_4 PF04566.8 EIE89620.1 - 0.014 15.1 11.5 13 5.6 0.0 7.6 9 0 0 9 9 9 0 RNA polymerase Rpb2, domain 4 PilJ PF13675.1 EIE89620.1 - 2.8 8.3 12.0 3.6 7.9 0.0 6.4 8 0 0 8 8 8 0 Type IV pili methyl-accepting chemotaxis transducer N-term HsbA PF12296.3 EIE89621.1 - 2e-17 63.1 11.5 7.4e-17 61.3 5.1 1.8 1 1 1 2 2 2 2 Hydrophobic surface binding protein A NPV_P10 PF05531.7 EIE89621.1 - 0.021 15.0 7.1 0.82 9.9 0.1 2.9 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein P16-Arc PF04699.9 EIE89621.1 - 0.034 14.1 0.4 0.062 13.3 0.1 1.5 1 1 0 1 1 1 0 ARP2/3 complex 16 kDa subunit (p16-Arc) RE_HindVP PF09519.5 EIE89621.1 - 0.036 12.9 0.3 0.047 12.5 0.2 1.1 1 0 0 1 1 1 0 HindVP restriction endonuclease Serine_rich PF08824.5 EIE89621.1 - 0.092 12.4 0.9 8.5 6.0 0.2 2.0 1 1 1 2 2 2 0 Serine rich protein interaction domain RTX_C PF08339.5 EIE89621.1 - 1.2 8.8 8.2 2 8.1 1.8 2.3 1 1 1 2 2 2 0 RTX C-terminal domain ATP-grasp_2 PF08442.5 EIE89622.1 - 1.7e-79 265.9 0.2 2.8e-79 265.2 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 EIE89622.1 - 1.7e-24 86.1 0.6 2.9e-24 85.4 0.4 1.4 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 EIE89622.1 - 1.1e-09 37.8 0.0 2.3e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 EIE89622.1 - 1.8e-05 24.3 0.9 0.015 14.8 0.0 3.1 2 1 0 3 3 3 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain PASTA PF03793.14 EIE89622.1 - 0.0035 16.9 1.7 2.2 8.0 0.0 3.6 3 0 0 3 3 3 2 PASTA domain ATP-grasp_4 PF13535.1 EIE89622.1 - 0.0092 15.7 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 EIE89622.1 - 0.032 13.5 0.2 0.53 9.5 0.0 2.4 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, ATP binding domain Succ_CoA_lig PF13607.1 EIE89622.1 - 0.059 12.9 0.3 3.1 7.3 0.0 2.5 1 1 1 2 2 2 0 Succinyl-CoA ligase like flavodoxin domain NT-C2 PF10358.4 EIE89622.1 - 0.068 12.6 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 N-terminal C2 in EEIG1 and EHBP1 proteins HipA_N PF07805.7 EIE89622.1 - 0.12 12.5 0.1 0.75 10.0 0.0 2.4 3 0 0 3 3 3 0 HipA-like N-terminal domain Sugar_tr PF00083.19 EIE89623.1 - 2.7e-100 336.0 21.1 3.3e-100 335.8 14.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIE89623.1 - 9.3e-26 90.3 36.1 1.3e-18 66.8 10.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EIE89623.1 - 0.0014 16.9 1.8 0.0014 16.9 1.3 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF1228 PF06779.9 EIE89623.1 - 1.1 9.3 11.2 0.89 9.6 0.2 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) RNase_T PF00929.19 EIE89624.1 - 4.7e-31 108.2 0.1 5.6e-31 108.0 0.1 1.0 1 0 0 1 1 1 1 Exonuclease NKWYS PF10364.4 EIE89624.1 - 0.016 14.9 0.6 0.034 13.8 0.4 1.5 1 0 0 1 1 1 0 Putative capsular polysaccharide synthesis protein PsbU PF06514.6 EIE89624.1 - 0.05 13.4 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Photosystem II 12 kDa extrinsic protein (PsbU) SCP2_2 PF13530.1 EIE89624.1 - 0.073 12.4 0.0 0.12 11.7 0.0 1.4 1 1 0 1 1 1 0 Sterol carrier protein domain GATA PF00320.22 EIE89625.1 - 7.5e-18 63.5 4.0 1.6e-17 62.5 2.8 1.6 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.5 EIE89625.1 - 7.8e-15 54.1 2.2 1.9e-14 52.9 1.5 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) AMP-binding PF00501.23 EIE89627.1 - 4.9e-95 318.3 0.0 6.4e-95 317.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EIE89627.1 - 0.023 15.6 0.0 0.054 14.4 0.0 1.6 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain CutA1 PF03091.10 EIE89628.1 - 0.093 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 CutA1 divalent ion tolerance protein TFIIS_C PF01096.13 EIE89629.1 - 1e-16 60.2 1.8 1e-16 60.2 1.2 2.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EIE89629.1 - 9.4e-05 22.0 17.3 0.00081 19.0 3.1 3.1 2 1 0 2 2 2 1 RNA polymerases M/15 Kd subunit zinc_ribbon_2 PF13240.1 EIE89629.1 - 0.00018 20.9 13.4 0.17 11.3 0.1 3.7 4 0 0 4 4 4 3 zinc-ribbon domain Lar_restr_allev PF14354.1 EIE89629.1 - 0.0007 19.8 0.4 0.0007 19.8 0.3 2.9 2 1 0 2 2 2 1 Restriction alleviation protein Lar DZR PF12773.2 EIE89629.1 - 0.00099 18.8 9.3 0.078 12.8 0.4 3.0 2 1 0 2 2 2 2 Double zinc ribbon DUF523 PF04463.7 EIE89629.1 - 0.001 18.8 4.2 0.0024 17.6 2.9 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF523) Terminase_GpA PF05876.7 EIE89629.1 - 0.01 14.1 2.8 0.014 13.8 1.9 1.3 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) IBR PF01485.16 EIE89629.1 - 0.016 15.0 8.7 0.25 11.2 0.2 2.5 2 1 0 2 2 2 0 IBR domain TF_Zn_Ribbon PF08271.7 EIE89629.1 - 0.037 13.3 11.7 0.44 9.9 1.8 3.1 2 2 0 2 2 2 0 TFIIB zinc-binding zf-ribbon_3 PF13248.1 EIE89629.1 - 0.041 13.0 17.2 0.41 9.9 0.2 3.5 3 1 1 4 4 4 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.2 EIE89629.1 - 0.046 13.5 1.5 0.046 13.5 1.1 3.2 2 1 1 3 3 3 0 Transposase zinc-ribbon domain zf-IS66 PF13005.2 EIE89629.1 - 0.058 13.3 11.8 5.7 7.0 0.1 4.1 4 0 0 4 4 4 0 zinc-finger binding domain of transposase IS66 DNA_ligase_ZBD PF03119.11 EIE89629.1 - 0.06 13.0 6.5 2.5 7.8 0.0 2.5 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain eIF-5_eIF-2B PF01873.12 EIE89629.1 - 0.062 12.9 0.4 0.062 12.9 0.3 2.0 2 1 0 2 2 2 0 Domain found in IF2B/IF5 Baculo_LEF5_C PF11792.3 EIE89629.1 - 0.072 12.4 0.9 0.072 12.4 0.6 3.0 3 1 0 3 3 3 0 Baculoviridae late expression factor 5 C-terminal domain NOB1_Zn_bind PF08772.6 EIE89629.1 - 0.11 12.3 9.9 1.6 8.5 0.6 3.4 2 1 1 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like Prok-RING_1 PF14446.1 EIE89629.1 - 0.18 11.5 10.4 0.37 10.5 1.5 3.2 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 A2L_zn_ribbon PF08792.5 EIE89629.1 - 0.24 10.9 16.2 4.9 6.7 0.6 4.1 4 0 0 4 4 4 0 A2L zinc ribbon domain Rpr2 PF04032.11 EIE89629.1 - 0.29 11.0 9.1 0.39 10.6 3.6 2.5 2 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-CSL PF05207.8 EIE89629.1 - 0.31 10.5 0.2 0.31 10.5 0.1 3.6 2 2 0 3 3 3 0 CSL zinc finger ArfGap PF01412.13 EIE89629.1 - 0.32 10.7 6.6 0.2 11.4 1.1 2.1 1 1 1 2 2 2 0 Putative GTPase activating protein for Arf GATA PF00320.22 EIE89629.1 - 0.55 9.6 9.4 1.5 8.2 0.1 3.1 3 0 0 3 3 3 0 GATA zinc finger Viral_NABP PF05515.6 EIE89629.1 - 0.58 10.4 4.2 0.24 11.6 1.0 1.9 1 1 1 2 2 2 0 Viral nucleic acid binding zf-HYPF PF07503.7 EIE89629.1 - 0.67 9.4 0.1 0.67 9.4 0.0 3.6 4 0 0 4 4 3 0 HypF finger C1_1 PF00130.17 EIE89629.1 - 0.74 9.5 7.0 0.93 9.2 0.4 2.5 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) OrfB_Zn_ribbon PF07282.6 EIE89629.1 - 0.75 9.4 9.3 4.2 7.1 2.3 2.8 1 1 2 3 3 3 0 Putative transposase DNA-binding domain zf-TFIIB PF13453.1 EIE89629.1 - 0.76 9.0 9.6 0.15 11.2 1.1 2.5 2 1 0 2 2 2 0 Transcription factor zinc-finger DUF164 PF02591.10 EIE89629.1 - 0.93 9.3 8.5 4.3 7.2 0.1 3.8 4 0 0 4 4 4 0 Putative zinc ribbon domain PHD PF00628.24 EIE89629.1 - 1 9.1 9.9 0.59 9.8 0.5 2.5 2 1 0 2 2 2 0 PHD-finger Zn_ribbon_recom PF13408.1 EIE89629.1 - 1.1 9.6 10.0 9.2 6.6 2.4 3.3 3 1 0 3 3 3 0 Recombinase zinc beta ribbon domain zf-RING_3 PF14369.1 EIE89629.1 - 1.3 9.1 10.3 18 5.4 0.1 3.5 4 0 0 4 4 3 0 zinc-finger Nudix_N_2 PF14803.1 EIE89629.1 - 1.3 8.7 15.2 6.6 6.5 0.1 3.9 3 1 0 3 3 3 0 Nudix N-terminal zinc-ribbons_6 PF07191.7 EIE89629.1 - 1.3 8.8 9.4 0.97 9.2 0.3 2.8 2 1 0 2 2 2 0 zinc-ribbons PolC_DP2 PF03833.8 EIE89629.1 - 1.8 6.1 4.9 0.41 8.2 1.1 1.5 1 1 1 2 2 2 0 DNA polymerase II large subunit DP2 DUF2387 PF09526.5 EIE89629.1 - 1.8 8.5 8.5 0.52 10.2 0.2 2.8 1 1 1 2 2 2 0 Probable metal-binding protein (DUF2387) Zn-ribbon_8 PF09723.5 EIE89629.1 - 4.3 7.3 20.8 3 7.8 0.1 4.3 4 1 1 5 5 4 0 Zinc ribbon domain RIG-I_C-RD PF11648.3 EIE89629.1 - 4.9 7.0 6.4 0.85 9.4 1.4 1.8 1 1 1 2 2 2 0 C-terminal domain of RIG-I Ribosomal_L31e PF01198.14 EIE89630.1 - 1.9e-31 107.5 3.1 2.3e-31 107.2 2.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e DDE_3 PF13358.1 EIE89631.1 - 8.1e-29 100.2 0.0 1.4e-28 99.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Ribosomal_S19 PF00203.16 EIE89632.1 - 2.6e-34 116.6 0.2 3.6e-34 116.2 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 FliH PF02108.11 EIE89632.1 - 0.1 12.4 0.0 0.13 12.1 0.0 1.1 1 0 0 1 1 1 0 Flagellar assembly protein FliH PIF1 PF05970.9 EIE89634.1 - 4.3e-16 58.8 0.2 5.2e-16 58.5 0.1 1.1 1 0 0 1 1 1 1 PIF1-like helicase Herpes_Helicase PF02689.9 EIE89634.1 - 0.00011 20.2 0.0 0.00012 19.9 0.0 1.0 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.1 EIE89634.1 - 0.0022 18.0 0.0 0.0038 17.3 0.0 1.5 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain RVT_1 PF00078.22 EIE89635.1 - 2.1e-11 43.6 2.1 5.1e-11 42.3 0.4 2.4 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP PF00077.15 EIE89635.1 - 0.011 15.6 0.3 0.048 13.5 0.1 2.3 2 0 0 2 2 2 0 Retroviral aspartyl protease DUF2361 PF10153.4 EIE89635.1 - 0.096 12.8 2.7 0.24 11.5 1.9 1.6 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2361) rve PF00665.21 EIE89636.1 - 1.8e-24 86.1 0.0 5.8e-24 84.5 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE89636.1 - 1.1e-15 57.6 0.1 2.3e-15 56.5 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE89636.1 - 9.2e-11 41.2 0.6 2.6e-10 39.8 0.4 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 EIE89636.1 - 0.00038 19.8 0.1 0.0011 18.3 0.1 1.9 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger UBN2_2 PF14227.1 EIE89636.1 - 0.017 14.6 1.0 0.34 10.4 0.0 2.8 3 0 0 3 3 3 0 gag-polypeptide of LTR copia-type rve_3 PF13683.1 EIE89636.1 - 0.027 14.0 0.0 0.089 12.3 0.0 1.9 1 0 0 1 1 1 0 Integrase core domain UBN2 PF14223.1 EIE89636.1 - 0.063 13.0 0.6 0.16 11.7 0.1 1.9 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type rve PF00665.21 EIE89637.1 - 4.6e-20 71.9 0.0 3.4e-19 69.1 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.19 EIE89637.1 - 8.4e-08 31.7 0.1 1.8e-07 30.6 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Integrase_Zn PF02022.14 EIE89637.1 - 0.013 14.9 0.4 0.051 13.0 0.3 2.1 1 0 0 1 1 1 0 Integrase Zinc binding domain zf-H2C2 PF09337.5 EIE89637.1 - 0.15 11.4 1.4 0.64 9.4 0.3 2.3 2 0 0 2 2 2 0 His(2)-Cys(2) zinc finger HTH_Tnp_Tc3_2 PF01498.13 EIE89638.1 - 3.3e-19 68.7 0.7 3.3e-19 68.7 0.5 2.4 2 1 1 3 3 3 1 Transposase HTH_29 PF13551.1 EIE89638.1 - 1.2e-06 28.6 0.9 2.6e-06 27.5 0.6 1.6 1 1 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.1 EIE89638.1 - 8.5e-05 23.2 3.8 0.00025 21.7 0.2 2.9 2 1 1 3 3 3 1 Homeodomain-like domain HTH_23 PF13384.1 EIE89638.1 - 0.00031 20.3 0.6 0.042 13.5 0.0 3.4 3 0 0 3 3 3 1 Homeodomain-like domain HTH_21 PF13276.1 EIE89638.1 - 0.0079 16.1 0.3 0.38 10.7 0.0 3.0 2 1 2 4 4 4 1 HTH-like domain NUMOD3 PF07460.6 EIE89638.1 - 0.038 13.8 0.1 0.34 10.8 0.1 2.2 2 0 0 2 2 2 0 NUMOD3 motif (2 copies) RVT_1 PF00078.22 EIE89639.1 - 3.2e-26 92.0 0.0 5.4e-26 91.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EIE89639.1 - 5.2e-08 32.5 0.0 1.6e-07 30.9 0.0 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EIE89639.1 - 6.2e-05 23.0 0.0 0.00015 21.7 0.0 1.7 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SYCE1 PF15233.1 EIE89639.1 - 0.012 15.5 1.5 0.016 15.1 0.3 1.7 2 0 0 2 2 2 0 Synaptonemal complex central element protein 1 TBPIP PF07106.8 EIE89639.1 - 0.33 10.4 0.1 0.62 9.5 0.0 1.3 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF972 PF06156.8 EIE89639.1 - 0.37 11.1 0.1 0.72 10.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Serglycin PF04360.7 EIE89639.1 - 1.6 8.4 11.6 0.087 12.5 2.6 2.4 2 0 0 2 2 2 0 Serglycin RVT_1 PF00078.22 EIE89641.1 - 2e-27 95.9 0.0 3.2e-27 95.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EIE89641.1 - 1.4e-14 53.7 0.1 4.2e-14 52.1 0.0 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EIE89641.1 - 9.3e-06 25.7 0.1 2.6e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family FlxA PF14282.1 EIE89641.1 - 0.18 11.8 3.6 0.33 10.9 2.5 1.4 1 0 0 1 1 1 0 FlxA-like protein Serglycin PF04360.7 EIE89641.1 - 0.81 9.4 11.2 0.079 12.6 2.6 2.6 2 0 0 2 2 2 0 Serglycin Asp_protease_2 PF13650.1 EIE89642.1 - 2.8e-05 24.5 0.0 9.2e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EIE89642.1 - 0.00043 20.0 0.0 0.00088 19.0 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.5 EIE89642.1 - 0.0039 16.7 0.1 0.008 15.7 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 EIE89642.1 - 0.021 14.7 0.0 0.077 12.9 0.0 2.1 1 0 0 1 1 1 0 Retroviral aspartyl protease rve PF00665.21 EIE89644.1 - 2.1e-17 63.3 0.0 4.7e-17 62.2 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE89644.1 - 6.9e-17 61.5 0.1 1.6e-16 60.3 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE89644.1 - 5.5e-09 35.5 1.0 1.2e-08 34.5 0.7 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.1 EIE89644.1 - 1.7e-07 31.6 0.1 4.3e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 EIE89644.1 - 6e-07 29.3 0.1 2.4e-06 27.4 0.0 2.1 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EIE89644.1 - 0.00046 19.9 0.0 0.0011 18.7 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.5 EIE89644.1 - 0.0067 15.9 0.2 0.061 12.8 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease Tudor-knot PF11717.3 EIE89644.1 - 0.038 13.7 0.2 0.11 12.2 0.2 1.7 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain Peptidase_M3_N PF08439.5 EIE89644.1 - 0.041 13.9 0.3 0.16 12.0 0.2 2.0 1 0 0 1 1 1 0 Oligopeptidase F Retrotrans_gag PF03732.12 EIE89645.1 - 0.00014 21.8 1.7 0.00081 19.4 0.0 2.9 3 1 0 3 3 3 1 Retrotransposon gag protein DUF342 PF03961.8 EIE89645.1 - 0.026 12.9 3.1 0.042 12.2 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) IncA PF04156.9 EIE89645.1 - 0.072 12.6 3.8 0.12 11.9 2.6 1.3 1 0 0 1 1 1 0 IncA protein FlxA PF14282.1 EIE89645.1 - 0.1 12.5 6.1 0.1 12.5 1.2 2.5 1 1 1 2 2 2 0 FlxA-like protein V-SNARE PF05008.10 EIE89645.1 - 7.2 6.8 14.3 0.18 11.9 4.5 2.4 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus V_ATPase_I PF01496.14 EIE89645.1 - 9.5 3.9 8.1 13 3.4 5.2 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DDE_Tnp_IS1595 PF12762.2 EIE89646.1 - 2.9e-06 27.2 0.1 5.3e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 ISXO2-like transposase domain Cut8_M PF14483.1 EIE89647.1 - 0.029 14.1 0.1 0.17 11.7 0.0 2.3 2 0 0 2 2 2 0 Cut8 dimerisation domain Rsd_AlgQ PF04353.8 EIE89647.1 - 0.032 13.9 0.4 0.053 13.2 0.2 1.3 1 0 0 1 1 1 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ DDE_3 PF13358.1 EIE89648.1 - 2.4e-20 72.7 0.1 4.9e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE89648.1 - 1.6e-15 56.9 2.6 3e-15 56.0 0.5 2.3 3 0 0 3 3 2 1 Transposase HTH_29 PF13551.1 EIE89648.1 - 1.7e-06 28.1 0.3 5.2e-06 26.5 0.2 1.9 2 0 0 2 2 1 1 Winged helix-turn helix HTH_38 PF13936.1 EIE89648.1 - 1.2e-05 24.7 0.1 3.3e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.1 EIE89648.1 - 8e-05 22.1 0.1 0.0028 17.2 0.0 2.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.1 EIE89648.1 - 0.00012 22.8 3.2 0.019 15.7 0.1 3.6 4 0 0 4 4 3 1 Homeodomain-like domain Sigma70_r4_2 PF08281.7 EIE89648.1 - 0.00092 18.6 1.3 0.024 14.0 0.0 3.2 4 0 0 4 4 4 1 Sigma-70, region 4 HTH_28 PF13518.1 EIE89648.1 - 0.0013 18.7 0.0 0.0056 16.6 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_21 PF13276.1 EIE89648.1 - 0.0014 18.6 0.1 0.13 12.2 0.0 2.9 3 0 0 3 3 3 1 HTH-like domain rve PF00665.21 EIE89648.1 - 0.0042 17.1 0.0 0.012 15.6 0.0 2.0 2 1 0 2 2 2 1 Integrase core domain HTH_7 PF02796.10 EIE89648.1 - 0.0045 16.8 1.8 0.1 12.4 0.0 2.8 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase LacI PF00356.16 EIE89648.1 - 0.017 14.7 1.7 2.8 7.6 0.2 2.7 3 0 0 3 3 3 0 Bacterial regulatory proteins, lacI family HTH_Tnp_4 PF13613.1 EIE89648.1 - 0.022 14.2 0.1 0.057 12.9 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease DUF2857 PF11198.3 EIE89648.1 - 0.038 13.4 0.0 0.073 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2857) CPSase_L_D3 PF02787.14 EIE89648.1 - 0.052 13.3 0.0 0.14 11.8 0.0 1.7 2 0 0 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain HTH_36 PF13730.1 EIE89648.1 - 0.07 13.2 0.3 4.1 7.6 0.0 3.0 3 0 0 3 3 2 0 Helix-turn-helix domain Sigma70_r4 PF04545.11 EIE89648.1 - 0.12 11.7 0.4 0.79 9.0 0.0 2.6 4 0 0 4 4 4 0 Sigma-70, region 4 HTH_Tnp_ISL3 PF13542.1 EIE89648.1 - 0.17 11.0 2.8 8.4 5.6 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 HTH_17 PF12728.2 EIE89648.1 - 0.2 11.9 2.4 15 5.9 0.1 3.2 3 0 0 3 3 3 0 Helix-turn-helix domain DDE_3 PF13358.1 EIE89650.1 - 2.2e-19 69.6 0.0 4.1e-19 68.7 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE89650.1 - 9.9e-10 38.3 3.5 1.1e-09 38.1 0.7 2.2 2 0 0 2 2 2 1 Transposase HTH_Tnp_4 PF13613.1 EIE89650.1 - 0.0044 16.5 0.0 0.0084 15.6 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease FAM70 PF14967.1 EIE89650.1 - 0.012 14.8 0.0 0.018 14.2 0.0 1.2 1 0 0 1 1 1 0 FAM70 protein HTH_23 PF13384.1 EIE89650.1 - 0.071 12.7 0.0 0.17 11.5 0.0 1.7 1 0 0 1 1 1 0 Homeodomain-like domain RVT_1 PF00078.22 EIE89651.1 - 1.8e-22 79.7 0.6 4e-22 78.6 0.4 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EIE89651.1 - 2.4e-07 30.8 0.1 0.0021 18.1 0.0 2.7 1 1 1 2 2 2 2 Integrase core domain RVP PF00077.15 EIE89651.1 - 9.7e-07 28.6 0.0 2.3e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EIE89651.1 - 9.7e-06 25.3 0.0 2.2e-05 24.1 0.0 1.6 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EIE89651.1 - 1.5e-05 25.4 0.0 2.8e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.18 EIE89651.1 - 0.0034 17.2 1.3 0.0034 17.2 0.9 2.2 2 0 0 2 2 2 1 Zinc knuckle RVP_2 PF08284.6 EIE89651.1 - 0.0041 17.0 0.0 0.0083 16.0 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease rve_3 PF13683.1 EIE89651.1 - 0.03 13.8 0.0 0.11 12.0 0.0 2.0 1 0 0 1 1 1 0 Integrase core domain Asp_protease PF09668.5 EIE89651.1 - 0.091 12.3 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC_2 PF13696.1 EIE89651.1 - 0.75 9.3 4.7 0.19 11.2 0.4 2.1 2 0 0 2 2 2 0 Zinc knuckle DDE_3 PF13358.1 EIE89652.1 - 1.7e-21 76.4 0.0 2.8e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE89652.1 - 5e-05 23.2 0.2 5e-05 23.2 0.1 1.8 2 0 0 2 2 2 1 Transposase Sigma70_r1_2 PF00140.15 EIE89652.1 - 0.005 16.4 0.1 0.01 15.4 0.1 1.5 1 0 0 1 1 1 1 Sigma-70 factor, region 1.2 SNF2_N PF00176.18 EIE89653.1 - 3.7e-63 213.1 0.0 3.7e-63 213.1 0.0 2.4 2 0 0 2 2 2 1 SNF2 family N-terminal domain Chromo PF00385.19 EIE89653.1 - 1.9e-14 53.0 6.9 9e-08 31.6 0.1 3.5 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 EIE89653.1 - 7.7e-14 51.3 0.0 2.3e-13 49.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HTH_Tnp_Tc3_2 PF01498.13 EIE89654.1 - 3.9e-11 42.8 1.0 6.7e-11 42.0 0.3 1.6 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 EIE89654.1 - 0.0078 16.3 0.1 0.075 13.1 0.0 2.4 2 1 0 3 3 3 1 Winged helix-turn helix DUF273 PF03314.9 EIE89654.1 - 0.24 10.6 2.6 0.35 10.1 0.3 1.9 1 1 1 2 2 2 0 Protein of unknown function, DUF273 Mito_carr PF00153.22 EIE89655.1 - 1.2e-63 210.8 2.9 3.6e-21 74.6 0.4 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein GSAP-16 PF14959.1 EIE89657.1 - 0.073 12.8 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 gamma-Secretase-activating protein C-term Transposase_31 PF04754.7 EIE89659.1 - 0.022 14.1 0.1 0.067 12.5 0.0 1.8 2 0 0 2 2 2 0 Putative transposase, YhgA-like zf-RVT PF13966.1 EIE89660.1 - 8.6e-07 29.1 2.1 3.2e-06 27.3 1.5 2.0 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Imm28 PF15574.1 EIE89662.1 - 0.054 13.0 0.1 0.13 11.8 0.0 1.6 1 1 0 1 1 1 0 Immunity protein 28 DUF3045 PF11243.3 EIE89662.1 - 0.14 12.4 2.2 0.17 12.1 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3045) IBN_N PF03810.14 EIE89663.1 - 0.033 14.0 0.1 2.9 7.8 0.0 2.8 2 0 0 2 2 2 0 Importin-beta N-terminal domain RST PF12174.3 EIE89663.1 - 0.05 13.4 0.5 1.5 8.7 0.0 2.8 3 0 0 3 3 3 0 RCD1-SRO-TAF4 (RST) plant domain Fungal_trans PF04082.13 EIE89664.1 - 4.3e-43 147.0 0.4 8.7e-43 146.0 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIE89665.1 - 1.8e-08 34.1 9.2 2.9e-08 33.4 6.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pap_E4 PF02711.9 EIE89665.1 - 0.3 11.9 3.5 14 6.5 0.1 2.5 2 1 0 2 2 2 0 E4 protein Pterin_4a PF01329.14 EIE89666.1 - 1.8e-32 110.9 0.1 2e-32 110.8 0.0 1.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase SbcCD_C PF13558.1 EIE89667.1 - 1e-09 38.1 0.0 2.7e-09 36.8 0.0 1.7 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit Rad50_zn_hook PF04423.9 EIE89667.1 - 1.8e-05 24.0 3.4 4.3e-05 22.9 0.1 3.7 2 1 1 3 3 3 1 Rad50 zinc hook motif SMC_N PF02463.14 EIE89667.1 - 7e-05 22.1 13.9 0.00018 20.8 9.6 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_13 PF13166.1 EIE89667.1 - 0.075 11.4 83.2 0.015 13.7 10.0 5.0 1 1 2 5 5 5 0 AAA domain Chlam_vir PF05475.6 EIE89668.1 - 1 8.4 6.8 0.55 9.2 1.5 2.2 1 1 1 2 2 2 0 Chlamydia virulence protein PGP3-D FHA PF00498.21 EIE89669.1 - 2.5e-14 53.1 0.1 4.8e-14 52.2 0.1 1.5 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 EIE89669.1 - 3.8e-10 39.4 8.1 8.1e-10 38.3 5.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EIE89669.1 - 2.4e-06 27.5 4.8 9.3e-06 25.6 3.3 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EIE89669.1 - 2e-05 24.1 6.9 4.3e-05 23.0 4.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIE89669.1 - 0.00018 21.1 7.0 0.00041 20.0 4.8 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EIE89669.1 - 0.00058 19.8 9.2 0.0014 18.6 6.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EIE89669.1 - 0.00096 18.7 4.1 0.00096 18.7 2.9 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 EIE89669.1 - 0.02 14.6 3.7 0.042 13.5 2.5 1.6 1 0 0 1 1 1 0 PHD-finger zf-Apc11 PF12861.2 EIE89669.1 - 0.043 13.6 3.0 0.11 12.3 2.0 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger HD PF01966.17 EIE89670.1 - 0.0022 18.0 0.0 0.0027 17.7 0.0 1.3 1 0 0 1 1 1 1 HD domain Avirulence PF03377.8 EIE89670.1 - 0.068 11.8 0.0 0.08 11.6 0.0 1.0 1 0 0 1 1 1 0 Xanthomonas avirulence protein, Avr/PthA Pkinase PF00069.20 EIE89671.1 - 1.1e-51 175.5 0.0 1.4e-50 171.8 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE89671.1 - 5.1e-23 81.4 0.0 1.2e-16 60.6 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EIE89671.1 - 5.9e-05 22.1 0.1 0.0015 17.5 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EIE89671.1 - 0.00035 19.7 0.0 0.00063 18.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_C PF00433.19 EIE89671.1 - 0.00036 21.0 0.1 0.0006 20.2 0.1 1.4 1 0 0 1 1 1 1 Protein kinase C terminal domain APH PF01636.18 EIE89671.1 - 0.00051 19.8 1.3 0.066 12.9 0.3 2.5 2 1 1 3 3 3 2 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EIE89671.1 - 0.0042 15.9 0.0 0.0066 15.3 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Pox_ser-thr_kin PF05445.6 EIE89671.1 - 0.018 13.8 0.1 0.029 13.1 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.17 EIE89671.1 - 0.04 13.2 0.0 0.065 12.5 0.0 1.3 1 0 0 1 1 1 0 RIO1 family PDEase_I PF00233.14 EIE89672.1 - 2.6e-51 174.6 0.0 3.5e-51 174.2 0.0 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.17 EIE89672.1 - 0.00051 20.0 0.1 0.00081 19.4 0.1 1.5 1 0 0 1 1 1 1 HD domain LysM PF01476.15 EIE89673.1 - 2.7e-06 27.1 0.3 5.9e-06 26.0 0.2 1.6 1 0 0 1 1 1 1 LysM domain HC2 PF07382.6 EIE89673.1 - 0.002 18.0 14.5 0.0029 17.5 10.0 1.2 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 DNA_pol_viral_N PF00242.12 EIE89673.1 - 0.14 11.1 8.8 0.19 10.7 6.1 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain ABC2_membrane_3 PF12698.2 EIE89673.1 - 7.1 5.5 5.6 11 4.9 3.7 1.3 1 1 0 1 1 1 0 ABC-2 family transporter protein DEAD PF00270.24 EIE89674.1 - 1.5e-33 115.6 0.0 2e-33 115.2 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Flavi_DEAD PF07652.9 EIE89674.1 - 0.0095 15.6 0.1 7.8 6.2 0.0 3.1 3 0 0 3 3 3 2 Flavivirus DEAD domain RhoGAP PF00620.22 EIE89675.1 - 9.2e-51 171.4 0.1 9.2e-51 171.4 0.1 2.2 2 1 1 3 3 3 1 RhoGAP domain C1_1 PF00130.17 EIE89675.1 - 3.9e-07 29.6 7.0 6.8e-07 28.9 4.8 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) LPP PF04728.8 EIE89675.1 - 0.0053 16.5 1.3 0.099 12.4 0.1 2.6 2 0 0 2 2 2 1 Lipoprotein leucine-zipper COG2 PF06148.6 EIE89675.1 - 0.011 15.6 13.4 0.029 14.2 2.1 3.0 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 ArdA PF07275.6 EIE89675.1 - 0.065 13.4 2.6 0.87 9.8 0.3 2.4 2 0 0 2 2 2 0 Antirestriction protein (ArdA) ADIP PF11559.3 EIE89675.1 - 0.82 9.5 14.4 0.93 9.3 1.6 3.0 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding Striatin PF08232.7 EIE89675.1 - 4.8 7.4 13.7 2.9 8.1 1.0 2.8 2 1 0 2 2 2 0 Striatin family F-box-like PF12937.2 EIE89676.1 - 2.3e-09 36.8 1.8 2.3e-09 36.8 1.3 2.7 3 0 0 3 3 3 1 F-box-like LRR_6 PF13516.1 EIE89676.1 - 1.9e-07 30.3 21.3 1.3 9.2 0.0 10.0 11 0 0 11 11 11 3 Leucine Rich repeat LRR_4 PF12799.2 EIE89676.1 - 1.4e-06 27.7 2.2 1.5 8.5 0.0 5.9 5 2 1 6 6 6 2 Leucine Rich repeats (2 copies) F-box PF00646.28 EIE89676.1 - 0.0065 16.0 0.1 0.036 13.7 0.0 2.3 1 0 0 1 1 1 1 F-box domain LRR_1 PF00560.28 EIE89676.1 - 0.02 14.8 17.0 8.6 6.8 0.1 8.4 6 3 0 6 6 6 0 Leucine Rich Repeat Hormone_recep PF00104.25 EIE89676.1 - 0.086 11.9 1.3 3.3 6.7 0.0 3.5 4 1 1 5 5 5 0 Ligand-binding domain of nuclear hormone receptor LRR_7 PF13504.1 EIE89676.1 - 1.3 9.5 13.6 68 4.3 0.0 7.4 8 2 0 8 8 8 0 Leucine rich repeat Phage_HK97_TLTM PF06120.6 EIE89677.1 - 0.0088 15.4 0.2 0.01 15.1 0.2 1.0 1 0 0 1 1 1 1 Tail length tape measure protein FtsL PF04999.8 EIE89677.1 - 0.023 14.4 0.3 0.027 14.1 0.2 1.1 1 0 0 1 1 1 0 Cell division protein FtsL Tmpp129 PF10272.4 EIE89677.1 - 0.068 11.8 0.1 0.074 11.7 0.1 1.1 1 0 0 1 1 1 0 Putative transmembrane protein precursor DUF106 PF01956.11 EIE89677.1 - 0.13 11.7 0.9 0.16 11.4 0.6 1.1 1 0 0 1 1 1 0 Integral membrane protein DUF106 CD34_antigen PF06365.7 EIE89677.1 - 0.15 11.7 0.4 0.34 10.5 0.1 1.6 1 1 1 2 2 2 0 CD34/Podocalyxin family DUF2681 PF10883.3 EIE89677.1 - 0.2 11.8 1.6 0.42 10.8 1.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2681) DUF4381 PF14316.1 EIE89677.1 - 0.35 10.9 2.8 0.47 10.5 1.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4381) Aa_trans PF01490.13 EIE89678.1 - 4.4e-60 203.2 21.2 5.2e-60 203.0 14.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DDE_3 PF13358.1 EIE89679.1 - 2.9e-24 85.4 0.1 4.4e-24 84.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE89679.1 - 0.0071 16.4 0.0 0.013 15.6 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Phage_Integr_2 PF13009.1 EIE89680.1 - 0.019 13.9 0.0 0.019 13.8 0.0 1.0 1 0 0 1 1 1 0 Putative phage integrase PP2C PF00481.16 EIE89681.1 - 1.2e-66 224.7 0.1 3.3e-65 220.0 0.1 2.2 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EIE89681.1 - 0.00016 21.1 0.1 0.0014 18.1 0.0 2.4 3 0 0 3 3 3 1 Protein phosphatase 2C Bromodomain PF00439.20 EIE89682.1 - 1.1e-05 25.2 0.1 3.4e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 Bromodomain CH PF00307.26 EIE89683.1 - 0.00028 20.9 0.0 0.0003 20.7 0.0 1.1 1 0 0 1 1 1 1 Calponin homology (CH) domain EB1 PF03271.12 EIE89684.1 - 1.6e-14 53.6 0.4 3.1e-14 52.7 0.3 1.5 1 0 0 1 1 1 1 EB1-like C-terminal motif Herpes_UL6 PF01763.11 EIE89684.1 - 0.018 13.2 0.1 0.018 13.2 0.1 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like DivIC PF04977.10 EIE89684.1 - 0.056 12.9 0.3 0.093 12.2 0.2 1.4 1 0 0 1 1 1 0 Septum formation initiator FlxA PF14282.1 EIE89684.1 - 0.059 13.3 0.2 0.077 12.9 0.1 1.4 1 1 0 1 1 1 0 FlxA-like protein Suppressor_APC PF11414.3 EIE89684.1 - 0.11 12.2 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein Bromodomain PF00439.20 EIE89685.1 - 7.8e-51 169.9 1.2 2.7e-24 84.8 0.0 2.6 2 0 0 2 2 2 2 Bromodomain FlxA PF14282.1 EIE89685.1 - 0.0015 18.4 14.5 0.0015 18.4 10.0 2.6 2 1 1 3 3 3 1 FlxA-like protein DUF3573 PF12097.3 EIE89685.1 - 0.12 10.9 4.4 0.23 10.0 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DUF4407 PF14362.1 EIE89685.1 - 0.34 9.8 7.9 0.7 8.7 5.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3138 PF11336.3 EIE89685.1 - 0.34 9.0 0.5 0.47 8.5 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Sec62 PF03839.11 EIE89685.1 - 0.45 9.8 12.9 0.023 14.1 2.0 2.3 2 0 0 2 2 2 0 Translocation protein Sec62 MerR-DNA-bind PF09278.6 EIE89685.1 - 0.95 9.9 4.4 1.2 9.5 1.8 2.0 2 0 0 2 2 2 0 MerR, DNA binding HAUS-augmin3 PF14932.1 EIE89685.1 - 2 7.5 13.0 0.52 9.4 6.2 1.9 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 TraV PF09676.5 EIE89685.1 - 3 8.5 10.8 1.7 9.3 0.2 2.3 2 0 0 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) YL1 PF05764.8 EIE89685.1 - 3.3 7.2 31.6 0.16 11.5 11.1 2.1 2 0 0 2 2 2 0 YL1 nuclear protein DivIC PF04977.10 EIE89685.1 - 10 5.7 7.0 2.7 7.5 1.0 2.6 2 0 0 2 2 2 0 Septum formation initiator DUF4451 PF14616.1 EIE89686.1 - 6.3e-25 87.3 2.9 1.7e-24 85.9 2.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) CENP-B_dimeris PF09026.5 EIE89686.1 - 6.1 7.1 10.7 0.39 10.9 2.1 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain RNA_pol_Rpc4 PF05132.9 EIE89686.1 - 6.3 6.7 8.0 2.7 7.9 0.6 2.5 2 0 0 2 2 2 0 RNA polymerase III RPC4 DUF4611 PF15387.1 EIE89686.1 - 7.6 6.7 11.7 0.23 11.6 2.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) RRM_1 PF00076.17 EIE89688.1 - 5.8e-17 61.0 0.3 7.9e-17 60.6 0.2 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE89688.1 - 4.2e-15 55.4 0.1 6.2e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE89688.1 - 1.9e-12 46.8 0.1 2.6e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EIE89688.1 - 9e-05 22.2 0.1 0.00015 21.5 0.0 1.2 1 0 0 1 1 1 1 RNA binding motif Nup35_RRM_2 PF14605.1 EIE89688.1 - 0.00058 19.5 0.1 0.00095 18.8 0.1 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif SAP PF02037.22 EIE89689.1 - 9e-06 25.0 0.0 2e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 SAP domain RRM_1 PF00076.17 EIE89690.1 - 1.4e-16 59.9 0.4 2.5e-10 39.8 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE89690.1 - 9.1e-08 31.9 0.1 2e-05 24.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE89690.1 - 1.6e-05 24.6 0.1 0.027 14.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CHY PF05495.7 EIE89691.1 - 4.5e-12 45.9 15.8 4.5e-12 45.9 10.9 3.8 3 1 0 3 3 3 2 CHY zinc finger GATA PF00320.22 EIE89692.1 - 4.7e-30 102.6 18.5 4.3e-17 61.1 4.5 2.4 2 0 0 2 2 2 2 GATA zinc finger DZR PF12773.2 EIE89692.1 - 1.1e-05 25.0 7.2 0.0049 16.6 0.3 2.7 2 1 0 2 2 2 2 Double zinc ribbon TF_Zn_Ribbon PF08271.7 EIE89692.1 - 3.1e-05 23.1 6.3 0.038 13.3 0.1 3.2 1 1 1 3 3 3 3 TFIIB zinc-binding Zn-ribbon_8 PF09723.5 EIE89692.1 - 0.0033 17.3 0.6 2.5 8.1 0.0 2.6 2 0 0 2 2 2 2 Zinc ribbon domain zf-A20 PF01754.11 EIE89692.1 - 0.0051 16.3 0.3 0.0051 16.3 0.2 3.0 4 0 0 4 4 3 1 A20-like zinc finger eIF-5_eIF-2B PF01873.12 EIE89692.1 - 0.0061 16.2 3.5 0.44 10.2 0.0 2.6 3 0 0 3 3 3 2 Domain found in IF2B/IF5 FYVE PF01363.16 EIE89692.1 - 0.0064 16.3 1.7 0.023 14.5 1.1 1.9 1 1 0 1 1 1 1 FYVE zinc finger Elf1 PF05129.8 EIE89692.1 - 0.03 14.0 2.5 0.98 9.1 0.1 2.8 1 1 0 2 2 2 0 Transcription elongation factor Elf1 like Zn_Tnp_IS1595 PF12760.2 EIE89692.1 - 0.032 14.0 7.2 0.91 9.3 0.2 2.5 2 1 0 2 2 2 0 Transposase zinc-ribbon domain zf-CHY PF05495.7 EIE89692.1 - 0.08 13.1 2.7 3.2 8.0 0.2 2.5 1 1 0 2 2 2 0 CHY zinc finger NMD3 PF04981.8 EIE89692.1 - 0.13 11.3 4.4 1.8 7.6 1.3 2.2 1 1 1 2 2 2 0 NMD3 family zinc_ribbon_2 PF13240.1 EIE89692.1 - 0.16 11.5 12.4 0.66 9.5 0.3 3.7 4 0 0 4 4 4 0 zinc-ribbon domain DUF3039 PF11238.3 EIE89692.1 - 0.21 11.0 0.9 8.7 5.8 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3039) zf-B_box PF00643.19 EIE89692.1 - 0.28 11.0 5.2 2.8 7.9 0.1 3.1 2 2 0 2 2 2 0 B-box zinc finger HypA PF01155.14 EIE89692.1 - 1 9.0 4.5 11 5.7 3.1 2.4 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family zf-ribbon_3 PF13248.1 EIE89692.1 - 3.8 6.8 18.0 1.5 8.1 0.2 3.5 2 1 1 3 3 3 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 EIE89692.1 - 5.4 6.7 15.9 0.74 9.5 0.7 2.9 2 1 1 3 3 2 0 Putative transposase DNA-binding domain SR-25 PF10500.4 EIE89692.1 - 9 5.6 14.1 0.28 10.5 5.4 1.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein 4HBT_3 PF13622.1 EIE89693.1 - 8.9e-24 84.6 0.0 1e-23 84.3 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF4358 PF14270.1 EIE89693.1 - 0.012 15.5 0.1 0.02 14.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4358) PGM_PMM_I PF02878.11 EIE89694.1 - 2.7e-36 124.0 0.1 4.8e-36 123.2 0.1 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 EIE89694.1 - 1.8e-27 95.5 0.0 3.4e-27 94.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 EIE89694.1 - 5.5e-16 58.7 0.1 2e-15 57.0 0.1 2.0 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EIE89694.1 - 2.6e-11 43.3 0.1 7.1e-11 41.9 0.1 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain DUF1900 PF08954.6 EIE89695.1 - 7.2e-54 180.9 0.0 2.8e-53 179.1 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 EIE89695.1 - 1.8e-32 110.7 0.1 3.2e-32 109.9 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 EIE89695.1 - 6.1e-25 86.1 0.6 6.5e-07 28.9 0.0 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat PspA_IM30 PF04012.7 EIE89695.1 - 0.0017 17.7 1.5 0.15 11.3 2.0 2.1 2 0 0 2 2 2 1 PspA/IM30 family Myosin_tail_1 PF01576.14 EIE89695.1 - 0.0023 15.7 2.5 0.003 15.3 1.7 1.0 1 0 0 1 1 1 1 Myosin tail Phage_GP20 PF06810.6 EIE89695.1 - 0.042 13.2 1.6 0.07 12.5 1.1 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 Tropomyosin_1 PF12718.2 EIE89695.1 - 0.06 13.1 4.6 0.09 12.6 3.2 1.2 1 0 0 1 1 1 0 Tropomyosin like Nup160 PF11715.3 EIE89695.1 - 0.11 10.5 0.3 5.7 4.9 0.0 2.2 1 1 1 2 2 2 0 Nucleoporin Nup120/160 NTS PF15447.1 EIE89695.1 - 0.19 12.1 1.0 0.41 11.0 0.7 1.5 1 0 0 1 1 1 0 N-terminal segments of PfEMP1 Shugoshin_N PF07558.6 EIE89695.1 - 0.23 11.2 1.2 0.52 10.0 0.8 1.6 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region Geminin PF07412.7 EIE89695.1 - 0.25 11.0 4.9 0.46 10.1 3.4 1.3 1 0 0 1 1 1 0 Geminin Transket_pyr PF02779.19 EIE89696.1 - 6.3e-46 156.1 0.0 1.2e-45 155.2 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EIE89696.1 - 5.7e-41 139.3 0.2 1.7e-40 137.7 0.1 1.9 2 0 0 2 2 2 1 Transketolase, C-terminal domain CP2 PF04516.10 EIE89697.1 - 2e-40 138.3 0.3 2.9e-40 137.8 0.2 1.2 1 0 0 1 1 1 1 CP2 transcription factor Med26 PF08711.6 EIE89697.1 - 0.11 11.9 0.2 0.24 10.9 0.1 1.5 1 0 0 1 1 1 0 TFIIS helical bundle-like domain WD40 PF00400.27 EIE89698.1 - 1e-56 186.8 12.6 9.2e-11 41.1 0.0 6.5 5 1 1 6 6 6 6 WD domain, G-beta repeat Tup_N PF08581.5 EIE89698.1 - 3e-22 78.6 11.6 4.9e-22 77.9 8.1 1.3 1 0 0 1 1 1 1 Tup N-terminal Nup160 PF11715.3 EIE89698.1 - 0.00044 18.5 0.2 0.66 8.0 0.0 3.5 1 1 2 3 3 3 1 Nucleoporin Nup120/160 Nbas_N PF15492.1 EIE89698.1 - 0.00049 19.2 0.1 2.7 6.9 0.0 3.2 1 1 1 3 3 3 1 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.11 EIE89698.1 - 0.00061 18.1 0.1 0.0036 15.6 0.1 2.2 1 1 1 2 2 2 1 Cytochrome D1 heme domain eIF2A PF08662.6 EIE89698.1 - 0.0053 16.4 0.0 1.2 8.8 0.0 3.1 3 1 0 4 4 3 1 Eukaryotic translation initiation factor eIF2A TPR_MLP1_2 PF07926.7 EIE89698.1 - 0.015 15.0 6.9 0.015 15.0 3.5 2.0 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF2362 PF10154.4 EIE89698.1 - 0.021 13.4 0.7 0.036 12.7 0.5 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) Nucleoporin_N PF08801.6 EIE89698.1 - 0.022 13.5 0.1 2.9 6.5 0.0 3.2 1 1 2 3 3 3 0 Nup133 N terminal like Proteasome_A_N PF10584.4 EIE89698.1 - 0.039 13.2 1.0 4.3 6.7 0.0 3.5 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature HOOK PF05622.7 EIE89698.1 - 0.043 11.6 4.6 0.059 11.1 3.2 1.1 1 0 0 1 1 1 0 HOOK protein DUF3450 PF11932.3 EIE89698.1 - 0.047 12.9 9.6 0.093 11.9 6.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) PD40 PF07676.7 EIE89698.1 - 0.076 12.7 1.6 17 5.2 0.0 4.6 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat APG6 PF04111.7 EIE89698.1 - 0.19 10.7 7.2 0.28 10.1 5.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF724 PF05266.9 EIE89698.1 - 0.46 10.0 5.3 0.73 9.4 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) CENP-F_leu_zip PF10473.4 EIE89698.1 - 0.5 10.2 8.5 0.89 9.4 5.9 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Prp19 PF08606.6 EIE89698.1 - 0.65 9.7 4.4 0.35 10.6 0.9 2.0 2 0 0 2 2 2 0 Prp19/Pso4-like Atg14 PF10186.4 EIE89698.1 - 0.96 8.3 7.0 1.6 7.5 4.8 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 COX6A PF02046.10 EIE89699.1 - 2.2e-27 95.2 0.3 2.3e-27 95.1 0.2 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa DUF601 PF04642.7 EIE89701.1 - 0.029 13.7 0.6 0.034 13.5 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF601 NAP PF00956.13 EIE89702.1 - 4.5e-85 284.6 7.3 4.5e-85 284.6 5.1 2.0 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) PBP1_TM PF14812.1 EIE89702.1 - 0.027 14.7 7.3 0.027 14.7 5.1 3.3 3 1 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RNase_H2_suC PF08615.6 EIE89702.1 - 0.064 13.0 1.5 1.7 8.5 0.1 2.5 1 1 1 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) RdRP PF05183.7 EIE89702.1 - 0.37 9.4 0.0 0.37 9.4 0.0 2.5 2 1 1 3 3 3 0 RNA dependent RNA polymerase Cwf_Cwc_15 PF04889.7 EIE89702.1 - 9.8 5.8 16.6 3.8 7.1 6.7 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein S-methyl_trans PF02574.11 EIE89703.1 - 1.2e-47 162.7 0.0 3.8e-47 161.0 0.0 1.6 1 1 1 2 2 2 1 Homocysteine S-methyltransferase DUF3444 PF11926.3 EIE89703.1 - 0.062 12.5 0.0 0.099 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3444) PcrB PF01884.12 EIE89703.1 - 0.13 11.4 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 PcrB family Sulfate_transp PF00916.15 EIE89704.1 - 1.4e-58 198.1 11.1 1.4e-58 198.1 7.7 1.7 2 0 0 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EIE89704.1 - 3.7e-30 103.4 2.5 3.7e-30 103.4 1.8 2.8 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EIE89704.1 - 5.8e-09 35.3 0.0 1.3e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 EIE89704.1 - 0.0071 16.3 0.0 0.073 13.1 0.0 2.3 2 0 0 2 2 2 1 STAS domain HLH PF00010.21 EIE89705.1 - 5.1e-19 67.7 3.1 2.4e-18 65.5 1.2 2.9 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain AMP-binding PF00501.23 EIE89706.1 - 3.4e-83 279.3 0.0 4.1e-83 279.1 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EIE89706.1 - 5.6e-16 59.2 0.1 1.1e-15 58.3 0.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GH3 PF03321.8 EIE89706.1 - 0.031 12.7 0.0 0.15 10.5 0.0 1.8 2 0 0 2 2 2 0 GH3 auxin-responsive promoter LEA_2 PF03168.8 EIE89707.1 - 3.6e-07 30.4 0.0 5.3e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Late embryogenesis abundant protein TIG PF01833.19 EIE89707.1 - 1.5 8.8 5.2 0.15 12.0 0.6 1.7 2 1 0 2 2 2 0 IPT/TIG domain Thr_synth_N PF14821.1 EIE89708.1 - 3.1e-28 97.5 0.0 6.4e-28 96.5 0.0 1.6 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.20 EIE89708.1 - 6.6e-21 74.8 0.0 1.2e-20 74.0 0.0 1.3 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PH PF00169.24 EIE89709.1 - 5.2e-09 36.2 5.7 9.4e-05 22.5 0.0 3.0 3 0 0 3 3 3 2 PH domain PH_9 PF15410.1 EIE89709.1 - 1.7e-05 24.9 7.3 0.048 13.8 0.0 4.0 3 1 0 3 3 3 2 Pleckstrin homology domain CENP-B_dimeris PF09026.5 EIE89709.1 - 1.1 9.5 27.4 0.063 13.5 6.1 3.2 3 0 0 3 3 3 0 Centromere protein B dimerisation domain NOA36 PF06524.7 EIE89709.1 - 6.7 5.8 25.6 0.12 11.6 4.6 2.4 2 0 0 2 2 2 0 NOA36 protein DUF4499 PF14934.1 EIE89710.1 - 1.1e-09 38.1 0.2 1.6e-09 37.5 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4499) FMO-like PF00743.14 EIE89711.1 - 0.0032 15.7 0.0 0.0038 15.4 0.0 1.1 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like zf-C2H2 PF00096.21 EIE89712.1 - 0.033 14.5 1.0 0.033 14.5 0.7 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIE89712.1 - 0.047 13.9 0.3 0.047 13.9 0.2 3.4 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2H2_4 PF13894.1 EIE89712.1 - 0.069 13.5 3.0 0.44 10.9 0.6 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-Di19 PF05605.7 EIE89712.1 - 0.24 11.5 1.6 10 6.3 0.1 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding V-SNARE_C PF12352.3 EIE89713.1 - 3.6e-13 49.3 1.5 3.6e-13 49.3 1.1 2.2 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 EIE89713.1 - 1.4e-07 31.0 3.7 1.5e-07 31.0 0.1 2.4 2 1 0 2 2 2 1 Sec20 TPR_MLP1_2 PF07926.7 EIE89713.1 - 0.016 14.9 12.4 0.2 11.3 3.8 2.3 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein HDAC4_Gln PF12203.3 EIE89713.1 - 0.021 14.7 2.3 0.021 14.7 1.6 2.5 3 0 0 3 3 3 0 Glutamine rich N terminal domain of histone deacetylase 4 Syntaxin-18_N PF10496.4 EIE89713.1 - 0.081 12.7 3.4 0.3 10.9 2.3 2.0 1 1 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus dTMP_synthase PF02593.9 EIE89713.1 - 0.09 12.1 0.0 0.61 9.3 0.0 1.9 1 1 1 2 2 2 0 Thymidylate synthase Orbi_VP5 PF00901.12 EIE89713.1 - 0.12 10.5 3.5 0.15 10.2 2.5 1.1 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 Tox-MPTase2 PF15638.1 EIE89713.1 - 0.47 9.9 4.0 0.57 9.6 2.3 1.6 1 1 0 1 1 1 0 Metallopeptidase toxin 2 Serine_rich PF08824.5 EIE89713.1 - 1.2 8.8 7.3 0.81 9.3 1.3 2.3 2 1 0 2 2 2 0 Serine rich protein interaction domain DUF948 PF06103.6 EIE89713.1 - 2 8.3 6.2 5.4 6.9 0.2 2.6 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) GRIP PF01465.15 EIE89714.1 - 5.1e-13 48.2 0.3 2.3e-12 46.2 0.2 2.2 1 0 0 1 1 1 1 GRIP domain DUF2184 PF09950.4 EIE89714.1 - 0.00033 19.8 1.5 0.00052 19.1 0.1 1.8 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2184) HlyD_2 PF12700.2 EIE89714.1 - 0.0027 16.9 8.0 0.0038 16.4 5.5 1.2 1 0 0 1 1 1 1 HlyD family secretion protein UPF0552 PF10574.4 EIE89714.1 - 0.25 10.7 5.9 0.35 10.3 1.8 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0552 DivIVA PF05103.8 EIE89714.1 - 3 7.9 28.1 0.031 14.3 8.1 3.1 2 1 1 3 3 3 0 DivIVA protein DUF2408 PF10303.4 EIE89714.1 - 3.3 7.8 22.2 0.94 9.5 5.7 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2408) GAS PF13851.1 EIE89714.1 - 5.9 6.0 33.8 0.35 10.0 11.4 2.8 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding SLA_LP_auto_ag PF05889.8 EIE89714.1 - 6.2 5.1 7.7 1.1 7.6 2.0 1.9 2 0 0 2 2 2 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Fib_alpha PF08702.5 EIE89714.1 - 7 6.7 28.2 3.7 7.6 5.2 3.2 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family bZIP_1 PF00170.16 EIE89715.1 - 9.7e-11 41.4 9.4 1.2e-10 41.1 6.5 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EIE89715.1 - 1.9e-10 40.3 10.0 2.1e-10 40.2 5.8 1.7 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 EIE89715.1 - 0.0017 18.6 6.2 0.0023 18.1 4.3 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor DUF2400 PF09674.5 EIE89715.1 - 0.0024 17.6 1.5 0.0025 17.5 1.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2400) Tektin PF03148.9 EIE89715.1 - 0.0059 15.1 3.5 0.0061 15.1 2.4 1.0 1 0 0 1 1 1 1 Tektin family DUF4201 PF13870.1 EIE89715.1 - 0.007 15.8 4.3 0.0081 15.6 3.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) Macoilin PF09726.4 EIE89715.1 - 0.012 14.0 3.8 0.012 13.9 2.7 1.0 1 0 0 1 1 1 0 Transmembrane protein GAS PF13851.1 EIE89715.1 - 0.017 14.3 5.6 0.02 14.1 3.9 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.4 EIE89715.1 - 0.028 14.2 1.8 0.028 14.2 1.3 1.1 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ADIP PF11559.3 EIE89715.1 - 0.039 13.8 7.9 0.042 13.7 5.5 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Phage_lysis PF03245.8 EIE89715.1 - 0.047 13.6 4.6 0.061 13.3 3.0 1.4 1 1 0 1 1 1 0 Bacteriophage Rz lysis protein TMP_2 PF06791.8 EIE89715.1 - 0.048 13.2 0.5 0.055 13.0 0.4 1.1 1 0 0 1 1 1 0 Prophage tail length tape measure protein Phlebovirus_NSM PF07246.6 EIE89715.1 - 0.051 12.7 2.8 0.052 12.7 1.9 1.0 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M FlaC_arch PF05377.6 EIE89715.1 - 0.058 13.2 2.4 0.083 12.7 1.6 1.2 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) L27_1 PF09058.5 EIE89715.1 - 0.079 12.8 0.5 0.19 11.5 0.2 1.9 1 1 1 2 2 2 0 L27_1 DUF972 PF06156.8 EIE89715.1 - 0.11 12.9 2.3 0.12 12.6 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) GHL13 PF14883.1 EIE89715.1 - 0.11 11.5 1.1 0.13 11.3 0.7 1.0 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase family 13 DUF4578 PF15147.1 EIE89715.1 - 0.12 12.7 1.1 0.15 12.4 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4578) Phage_T4_Ndd PF06591.6 EIE89715.1 - 0.13 11.8 0.3 0.14 11.7 0.2 1.1 1 0 0 1 1 1 0 T4-like phage nuclear disruption protein (Ndd) TSC22 PF01166.13 EIE89715.1 - 0.14 12.1 1.8 0.22 11.4 1.0 1.6 1 1 0 1 1 1 0 TSC-22/dip/bun family TMF_DNA_bd PF12329.3 EIE89715.1 - 0.17 11.7 3.5 0.22 11.3 2.4 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF904 PF06005.7 EIE89715.1 - 0.22 11.8 4.6 0.17 12.1 2.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF904) APG6 PF04111.7 EIE89715.1 - 0.28 10.2 5.8 0.31 10.0 4.0 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 Spc24 PF08286.6 EIE89715.1 - 0.36 10.5 3.0 0.45 10.2 2.1 1.1 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Prp18 PF02840.10 EIE89715.1 - 0.4 10.4 3.3 0.48 10.2 2.3 1.0 1 0 0 1 1 1 0 Prp18 domain DUF2937 PF11157.3 EIE89715.1 - 0.41 9.9 2.5 0.43 9.8 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) Nup54 PF13874.1 EIE89715.1 - 0.42 10.2 8.0 0.7 9.5 5.6 1.5 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 Lipase_GDSL_3 PF14606.1 EIE89715.1 - 0.51 10.0 3.3 0.64 9.7 0.2 1.9 1 1 1 2 2 2 0 GDSL-like Lipase/Acylhydrolase family DUF3251 PF11622.3 EIE89715.1 - 0.53 9.6 3.4 0.61 9.4 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) Jnk-SapK_ap_N PF09744.4 EIE89715.1 - 0.77 9.7 7.1 0.83 9.6 4.9 1.0 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Phage_GP20 PF06810.6 EIE89715.1 - 1.1 8.7 4.6 1.4 8.3 3.2 1.1 1 0 0 1 1 1 0 Phage minor structural protein GP20 CK_II_beta PF01214.13 EIE89716.1 - 4.6e-33 114.2 0.5 6.6e-24 84.4 0.1 2.0 1 1 1 2 2 2 2 Casein kinase II regulatory subunit Methyltransf_23 PF13489.1 EIE89718.1 - 6e-13 48.8 0.0 9.1e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIE89718.1 - 1.6e-07 31.6 0.0 2.9e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIE89718.1 - 4.6e-05 23.0 0.0 7.6e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIE89718.1 - 0.0004 20.6 0.0 0.00083 19.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIE89718.1 - 0.00073 19.9 0.0 0.0014 19.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 EIE89718.1 - 0.0011 18.1 0.0 0.0017 17.5 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_18 PF12847.2 EIE89718.1 - 0.0012 19.3 0.0 0.0021 18.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EIE89718.1 - 0.06 12.3 0.0 0.15 11.1 0.0 1.5 1 1 0 1 1 1 0 Putative methyltransferase Glyco_transf_15 PF01793.11 EIE89719.1 - 2.8e-128 427.5 7.6 2.8e-128 427.5 5.3 1.7 2 0 0 2 2 2 1 Glycolipid 2-alpha-mannosyltransferase Myb_DNA-bind_6 PF13921.1 EIE89719.1 - 9.2e-07 28.8 0.6 2.4e-06 27.5 0.0 2.1 3 0 0 3 3 3 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EIE89719.1 - 0.00015 21.7 2.8 0.17 11.9 0.1 3.0 3 0 0 3 3 3 2 Myb-like DNA-binding domain Cation_efflux PF01545.16 EIE89720.1 - 2.2e-45 154.9 0.4 2.6e-45 154.7 0.3 1.0 1 0 0 1 1 1 1 Cation efflux family DUF1449 PF07290.6 EIE89720.1 - 0.079 12.2 0.5 0.12 11.7 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1449) FMO-like PF00743.14 EIE89721.1 - 8.4e-34 116.6 0.0 1.1e-16 60.1 0.0 3.8 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EIE89721.1 - 1.3e-12 48.2 0.0 3.8e-11 43.4 0.0 2.5 2 1 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIE89721.1 - 4.1e-07 29.9 0.0 8.4e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EIE89721.1 - 1.7e-05 23.8 0.0 0.00014 20.8 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 EIE89721.1 - 0.0004 19.5 0.0 0.00069 18.7 0.0 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 EIE89721.1 - 0.00049 18.6 0.0 0.00068 18.2 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_9 PF13454.1 EIE89721.1 - 0.0012 18.6 0.1 0.054 13.2 0.0 3.2 4 0 0 4 4 4 1 FAD-NAD(P)-binding IlvN PF07991.7 EIE89721.1 - 0.0015 17.9 0.0 0.0029 16.9 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain Pyr_redox_2 PF07992.9 EIE89721.1 - 0.0021 17.9 0.0 0.097 12.5 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EIE89721.1 - 0.0024 18.2 0.1 0.023 15.0 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EIE89721.1 - 0.028 13.4 0.0 0.055 12.5 0.0 1.4 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase NAD_Gly3P_dh_N PF01210.18 EIE89721.1 - 0.041 13.5 0.0 0.068 12.8 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_binding_3 PF01494.14 EIE89721.1 - 0.058 12.4 0.1 0.092 11.7 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain 2-Hacid_dh_C PF02826.14 EIE89721.1 - 0.16 11.0 0.0 0.28 10.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 EIE89721.1 - 0.19 10.5 0.1 0.31 9.8 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_2 PF03446.10 EIE89721.1 - 0.21 11.4 0.0 0.35 10.6 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase DRIM PF07539.7 EIE89722.1 - 9.5e-46 154.7 1.2 3.6e-45 152.8 0.3 2.7 2 0 0 2 2 2 1 Down-regulated in metastasis HEAT PF02985.17 EIE89722.1 - 0.025 14.6 0.1 21 5.5 0.1 5.5 5 0 0 5 5 5 0 HEAT repeat Lyase_8 PF02278.13 EIE89723.1 - 5.8e-35 120.9 3.4 8.4e-35 120.4 2.4 1.1 1 0 0 1 1 1 1 Polysaccharide lyase family 8, super-sandwich domain Lyase_8_N PF08124.6 EIE89723.1 - 8e-17 61.0 0.2 1.6e-16 60.0 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide lyase family 8, N terminal alpha-helical domain Lyase_8_C PF02884.12 EIE89723.1 - 4.1e-09 36.3 0.1 1.3e-08 34.6 0.0 1.9 1 0 0 1 1 1 1 Polysaccharide lyase family 8, C-terminal beta-sandwich domain zf-C2H2 PF00096.21 EIE89725.1 - 0.0046 17.2 8.0 0.63 10.4 0.6 2.8 1 1 1 2 2 2 2 Zinc finger, C2H2 type SMN PF06003.7 EIE89725.1 - 0.014 14.5 0.5 0.016 14.3 0.3 1.1 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Stc1 PF12898.2 EIE89725.1 - 0.015 15.3 2.3 0.023 14.7 1.6 1.4 1 0 0 1 1 1 0 Stc1 domain C1_4 PF07975.7 EIE89725.1 - 0.026 14.5 2.4 0.045 13.7 1.7 1.4 1 0 0 1 1 1 0 TFIIH C1-like domain zf-C2H2_6 PF13912.1 EIE89725.1 - 0.043 13.7 5.0 0.2 11.6 3.4 2.0 1 1 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_4 PF13894.1 EIE89725.1 - 0.068 13.5 5.3 0.068 13.5 3.7 2.6 2 1 0 2 2 2 0 C2H2-type zinc finger Osteoregulin PF07175.6 EIE89725.1 - 0.16 11.8 1.3 0.24 11.1 0.9 1.3 1 0 0 1 1 1 0 Osteoregulin zf-met PF12874.2 EIE89725.1 - 1.4 9.1 5.2 5.8 7.2 0.6 2.7 1 1 1 2 2 2 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.1 EIE89725.1 - 2.9 8.3 11.2 0.66 10.3 2.6 2.7 2 0 0 2 2 2 0 Zinc-finger double domain Ras PF00071.17 EIE89726.1 - 5.1e-47 159.2 0.1 6e-47 159.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIE89726.1 - 3.1e-23 82.5 0.0 4e-23 82.1 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIE89726.1 - 5.1e-14 51.8 0.1 6.1e-14 51.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EIE89726.1 - 3.6e-05 23.0 0.0 4.3e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EIE89726.1 - 8.5e-05 22.4 0.0 0.0001 22.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EIE89726.1 - 0.016 14.6 0.0 0.035 13.5 0.0 1.5 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EIE89726.1 - 0.059 12.5 0.2 0.15 11.2 0.1 1.7 1 1 0 2 2 2 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 EIE89726.1 - 0.061 13.3 0.0 0.094 12.6 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 EIE89726.1 - 0.096 12.8 0.0 0.37 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.15 EIE89726.1 - 0.13 10.8 1.9 6.4 5.3 0.2 2.7 1 1 1 2 2 2 0 G-protein alpha subunit MIF4G PF02854.14 EIE89727.1 - 1.7e-63 213.8 10.0 7.8e-35 120.1 0.2 4.0 4 0 0 4 4 4 3 MIF4G domain Upf2 PF04050.9 EIE89727.1 - 3e-43 147.5 27.3 3e-43 147.5 19.0 2.9 4 0 0 4 4 4 1 Up-frameshift suppressor 2 Adap_comp_sub PF00928.16 EIE89728.1 - 5e-56 189.7 0.1 7.3e-56 189.1 0.1 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EIE89728.1 - 8.3e-06 25.5 1.3 1.4e-05 24.8 0.9 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain OB_NTP_bind PF07717.11 EIE89729.1 - 1.2e-30 105.6 0.0 3.7e-30 104.0 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EIE89729.1 - 1.3e-21 76.5 0.1 1.3e-21 76.5 0.1 4.2 3 1 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EIE89729.1 - 7.2e-14 51.4 0.0 1.8e-13 50.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EIE89729.1 - 7.6e-07 28.7 0.0 1.8e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EIE89729.1 - 1.1e-05 25.5 0.1 0.00026 21.1 0.0 3.0 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EIE89729.1 - 0.0006 18.8 0.0 0.0014 17.5 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein SRP54 PF00448.17 EIE89729.1 - 0.0028 17.1 0.0 0.022 14.2 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_14 PF13173.1 EIE89729.1 - 0.28 11.0 5.2 0.84 9.5 0.1 3.6 2 1 0 2 2 2 0 AAA domain Mito_carr PF00153.22 EIE89730.1 - 2.3e-75 248.4 1.0 1.5e-26 91.9 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 EIE89730.1 - 5.9e-13 48.7 9.1 0.0013 18.8 0.9 4.4 3 2 1 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 EIE89730.1 - 6.7e-13 47.3 9.1 5.1e-05 22.8 0.0 6.5 7 0 0 7 7 7 2 EF-hand domain EF-hand_1 PF00036.27 EIE89730.1 - 2.6e-12 45.0 8.1 5e-06 25.4 0.0 5.5 6 0 0 6 6 6 2 EF hand EF-hand_8 PF13833.1 EIE89730.1 - 4.6e-11 42.1 5.9 0.017 14.7 0.1 4.7 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 EIE89730.1 - 0.00017 20.7 3.8 0.012 14.9 0.1 3.1 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.1 EIE89730.1 - 0.064 13.1 0.5 9.9 6.1 0.0 3.9 4 0 0 4 4 4 0 EF-hand domain EF-hand_4 PF12763.2 EIE89730.1 - 8.6 6.1 7.2 3.1 7.6 0.5 3.3 2 2 2 4 4 4 0 Cytoskeletal-regulatory complex EF hand Aconitase PF00330.15 EIE89731.1 - 2.7e-158 527.3 0.1 2.4e-157 524.1 0.1 2.1 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EIE89731.1 - 2.1e-40 137.8 0.0 3.8e-40 137.0 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.8 EIE89731.1 - 0.096 11.2 0.0 0.21 10.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF521) ArfGap PF01412.13 EIE89732.1 - 2.2e-37 127.4 1.5 4.6e-37 126.3 0.1 2.3 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf PH PF00169.24 EIE89732.1 - 6.8e-14 51.9 2.5 8.7e-14 51.5 0.3 2.3 2 0 0 2 2 2 1 PH domain NAPRTase PF04095.11 EIE89732.1 - 0.025 13.8 0.8 1 8.5 0.2 2.6 1 1 1 2 2 2 0 Nicotinate phosphoribosyltransferase (NAPRTase) family Sel1 PF08238.7 EIE89733.1 - 1.1e-33 114.8 62.3 1.3e-05 25.6 0.0 11.8 12 1 0 12 12 12 9 Sel1 repeat TPR_6 PF13174.1 EIE89733.1 - 0.0096 16.3 0.1 0.0096 16.3 0.1 7.2 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_16 PF13432.1 EIE89733.1 - 4.5 8.0 34.7 0.11 13.1 2.1 7.0 6 1 1 7 7 7 0 Tetratricopeptide repeat Stk19 PF10494.4 EIE89734.1 - 4.1e-28 98.4 0.8 5.3e-28 98.0 0.6 1.2 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 Bromodomain PF00439.20 EIE89735.1 - 5.4e-45 151.2 6.0 1.2e-21 76.4 0.1 3.5 3 0 0 3 3 3 2 Bromodomain Arch_flagellin PF01917.11 EIE89736.1 - 0.11 12.0 0.5 0.14 11.7 0.3 1.2 1 0 0 1 1 1 0 Archaebacterial flagellin Fork_head PF00250.13 EIE89737.1 - 9.1e-33 112.1 0.2 9.1e-33 112.1 0.1 1.7 2 0 0 2 2 2 1 Fork head domain HAD PF12710.2 EIE89740.1 - 2.3e-13 50.7 0.0 9.1e-13 48.8 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EIE89740.1 - 2.8e-12 46.4 0.0 1e-11 44.6 0.0 1.9 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit E1-E2_ATPase PF00122.15 EIE89740.1 - 2.6e-10 39.7 0.6 7.6e-09 34.9 0.5 2.7 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EIE89740.1 - 1.4e-09 38.6 1.1 1.2e-06 29.1 0.5 2.7 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EIE89740.1 - 0.0011 18.6 0.2 0.0045 16.5 0.1 2.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase CusF_Ec PF11604.3 EIE89740.1 - 0.095 12.5 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 Copper binding periplasmic protein CusF PIG-S PF10510.4 EIE89742.1 - 1.1e-56 192.6 0.8 1.2e-56 192.5 0.6 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein EH_Signature PF15611.1 EIE89742.1 - 0.006 15.6 0.0 0.0084 15.2 0.0 1.1 1 0 0 1 1 1 1 EH_Signature domain Cas_Csy1 PF09611.5 EIE89742.1 - 0.04 12.8 0.1 0.046 12.6 0.1 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy1) PIG-S PF10510.4 EIE89743.1 - 7.1e-15 54.6 0.0 8.1e-15 54.4 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein XPG_N PF00752.12 EIE89744.1 - 8.6e-16 58.0 0.0 1.8e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain UBN2_2 PF14227.1 EIE89744.1 - 0.03 13.8 1.2 0.066 12.7 0.3 1.8 1 1 1 2 2 2 0 gag-polypeptide of LTR copia-type Baculo_PEP_C PF04513.7 EIE89744.1 - 0.12 12.1 1.7 0.34 10.7 1.1 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Nsp1_C PF05064.8 EIE89744.1 - 0.43 10.2 3.3 0.53 9.9 0.4 2.2 1 1 2 3 3 3 0 Nsp1-like C-terminal region CTNNB1_binding PF08347.6 EIE89744.1 - 2.4 8.3 6.1 5.1 7.3 0.9 2.1 1 1 0 2 2 2 0 N-terminal CTNNB1 binding zf-RING_2 PF13639.1 EIE89746.1 - 1.8e-16 59.6 5.1 2.5e-16 59.1 3.5 1.2 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EIE89746.1 - 1.6e-09 37.7 6.4 3.4e-09 36.6 4.4 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EIE89746.1 - 3.3e-09 36.3 4.2 4.9e-09 35.7 2.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EIE89746.1 - 1.3e-08 34.3 3.5 2e-08 33.7 2.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIE89746.1 - 1.4e-08 34.6 6.3 2e-08 34.1 4.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIE89746.1 - 3.8e-07 29.6 6.0 6e-07 29.0 4.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EIE89746.1 - 2e-06 27.5 1.6 3.3e-06 26.8 1.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.1 EIE89746.1 - 0.00059 19.5 0.9 0.00099 18.8 0.6 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 EIE89746.1 - 0.004 16.8 6.6 0.0071 16.0 0.6 2.7 3 0 0 3 3 3 1 RING-type zinc-finger Baculo_RING PF05883.6 EIE89746.1 - 0.0089 15.8 1.2 0.012 15.4 0.8 1.3 1 0 0 1 1 1 1 Baculovirus U-box/Ring-like domain Prok-RING_1 PF14446.1 EIE89746.1 - 0.025 14.2 6.6 0.21 11.3 1.8 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-C3HC4_4 PF15227.1 EIE89746.1 - 0.026 14.3 5.2 0.071 13.0 3.5 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EIE89746.1 - 0.052 13.1 3.8 0.11 12.1 2.6 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.3 EIE89746.1 - 0.067 12.7 3.7 0.12 11.9 2.6 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit RINGv PF12906.2 EIE89746.1 - 0.077 13.0 5.3 0.17 11.9 3.3 1.8 1 1 1 2 2 2 0 RING-variant domain Vps39_2 PF10367.4 EIE89746.1 - 0.086 13.0 1.8 0.73 10.0 0.3 2.2 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 FANCL_C PF11793.3 EIE89746.1 - 0.13 12.2 6.7 0.93 9.5 4.7 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.24 EIE89746.1 - 0.16 11.6 5.0 0.53 10.0 3.6 1.8 1 1 0 1 1 1 0 PHD-finger zf-HC5HC2H_2 PF13832.1 EIE89746.1 - 0.17 11.8 3.0 0.36 10.8 2.1 1.6 1 1 1 2 2 2 0 PHD-zinc-finger like domain Rtf2 PF04641.7 EIE89746.1 - 0.19 10.8 2.4 0.48 9.5 1.9 1.4 1 1 1 2 2 2 0 Rtf2 RING-finger C1_1 PF00130.17 EIE89746.1 - 0.35 10.6 5.7 1.4 8.7 1.7 2.5 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_4 PF14447.1 EIE89746.1 - 0.48 10.0 5.8 1.9 8.1 4.1 2.0 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-HC5HC2H PF13771.1 EIE89746.1 - 0.59 10.3 3.8 0.21 11.7 0.4 1.8 1 1 1 2 2 2 0 PHD-like zinc-binding domain zf-RING-like PF08746.6 EIE89746.1 - 0.74 9.8 4.1 2 8.5 2.9 1.7 1 1 0 1 1 1 0 RING-like domain zf-RING_3 PF14369.1 EIE89747.1 - 0.0095 15.9 0.2 0.018 15.0 0.1 1.5 1 0 0 1 1 1 1 zinc-finger PCI PF01399.22 EIE89748.1 - 2.3e-11 43.9 2.6 3.8e-11 43.2 0.4 2.1 2 0 0 2 2 2 1 PCI domain Atg14 PF10186.4 EIE89748.1 - 0.46 9.3 5.1 0.57 9.0 3.6 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Methyltransf_4 PF02390.12 EIE89749.1 - 0.0002 20.4 0.0 0.00022 20.3 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_11 PF08241.7 EIE89749.1 - 0.0011 19.4 0.0 0.0023 18.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIE89749.1 - 0.0017 17.9 0.0 0.0022 17.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIE89749.1 - 0.0043 17.0 0.0 0.0051 16.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIE89749.1 - 0.01 16.3 0.0 0.014 15.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 EIE89749.1 - 0.011 15.4 0.0 0.011 15.4 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain CmcI PF04989.7 EIE89749.1 - 0.037 13.3 0.0 0.051 12.8 0.0 1.2 1 0 0 1 1 1 0 Cephalosporin hydroxylase MTS PF05175.9 EIE89749.1 - 0.096 12.0 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain N-SET PF11764.3 EIE89750.1 - 0.05 13.5 0.0 0.1 12.5 0.0 1.5 1 1 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component N IMPDH PF00478.20 EIE89751.1 - 1.1e-138 461.9 4.4 1.2e-138 461.7 3.1 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 EIE89751.1 - 9.9e-13 47.6 0.0 2.8e-06 26.9 0.0 2.5 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.13 EIE89751.1 - 2.1e-10 40.0 0.8 9e-10 37.9 0.6 2.0 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.10 EIE89751.1 - 1.4e-09 37.5 2.2 1.6e-06 27.5 0.8 2.2 2 0 0 2 2 2 2 Nitronate monooxygenase His_biosynth PF00977.16 EIE89751.1 - 1.8e-05 24.1 2.6 0.0018 17.6 0.2 2.6 1 1 1 2 2 2 2 Histidine biosynthesis protein ThiG PF05690.9 EIE89751.1 - 0.00028 20.0 1.3 0.001 18.2 0.2 2.2 1 1 0 2 2 2 1 Thiazole biosynthesis protein ThiG Aldolase PF01081.14 EIE89751.1 - 0.029 13.5 0.7 0.079 12.1 0.0 2.0 2 0 0 2 2 2 0 KDPG and KHG aldolase PK PF00224.16 EIE89751.1 - 0.044 12.3 0.0 0.1 11.1 0.0 1.6 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain Cpn60_TCP1 PF00118.19 EIE89752.1 - 5.3e-145 483.7 2.4 6.1e-145 483.5 1.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CPT PF07931.7 EIE89752.1 - 0.042 13.4 0.1 0.33 10.5 0.1 2.2 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein DUF4241 PF14025.1 EIE89752.1 - 0.14 11.8 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4241) RVT_1 PF00078.22 EIE89755.1 - 3.1e-26 92.0 0.0 4.1e-26 91.6 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_3 PF13358.1 EIE89756.1 - 1.6e-09 37.6 0.0 2.2e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE89756.1 - 0.049 13.6 0.7 0.099 12.7 0.0 1.7 2 0 0 2 2 2 0 Transposase DUF1917 PF08939.5 EIE89760.1 - 0.016 14.9 1.3 0.021 14.5 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1917) RR_TM4-6 PF06459.7 EIE89760.1 - 0.098 12.5 5.6 0.1 12.4 3.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Vfa1 PF08432.5 EIE89760.1 - 0.41 10.6 13.4 0.53 10.2 9.3 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CDC45 PF02724.9 EIE89760.1 - 0.43 8.5 5.4 0.45 8.4 3.8 1.0 1 0 0 1 1 1 0 CDC45-like protein BTV_NS2 PF04514.7 EIE89760.1 - 0.52 9.1 10.2 0.63 8.8 7.1 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DDHD PF02862.12 EIE89760.1 - 0.68 9.6 3.3 0.76 9.5 2.3 1.1 1 0 0 1 1 1 0 DDHD domain Selenoprotein_S PF06936.6 EIE89760.1 - 0.75 9.2 9.5 0.92 9.0 6.6 1.1 1 0 0 1 1 1 0 Selenoprotein S (SelS) DUF1510 PF07423.6 EIE89760.1 - 1.1 8.5 10.2 1.4 8.2 7.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) NARP1 PF12569.3 EIE89760.1 - 1.4 7.5 12.3 1.7 7.3 8.5 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RNase_H2-Ydr279 PF09468.5 EIE89760.1 - 1.9 7.5 8.7 2.4 7.2 6.0 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) DUF2413 PF10310.4 EIE89760.1 - 1.9 7.1 8.9 2.5 6.7 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) RNA_pol_Rpc4 PF05132.9 EIE89760.1 - 5.9 6.8 7.5 8.3 6.4 5.2 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 Apelin PF15360.1 EIE89760.1 - 8.2 6.7 7.6 0.89 9.8 0.1 2.8 1 1 2 3 3 3 0 APJ endogenous ligand DUF1682 PF07946.9 EIE89760.1 - 9.9 4.9 15.4 12 4.6 10.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF1819 PF08849.6 EIE89761.1 - 0.017 14.5 0.3 0.025 13.9 0.2 1.3 1 0 0 1 1 1 0 Putative inner membrane protein (DUF1819) zf-CHY PF05495.7 EIE89762.1 - 1.3e-15 57.2 18.1 1.6e-15 56.9 12.5 1.1 1 0 0 1 1 1 1 CHY zinc finger zf-FPG_IleRS PF06827.9 EIE89762.1 - 0.0091 15.6 0.5 0.025 14.1 0.4 1.8 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS C1_4 PF07975.7 EIE89762.1 - 0.012 15.6 3.6 0.012 15.6 2.5 2.6 1 1 2 3 3 3 0 TFIIH C1-like domain NOB1_Zn_bind PF08772.6 EIE89762.1 - 0.023 14.5 1.9 0.023 14.5 1.3 1.7 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Zn_Tnp_IS1595 PF12760.2 EIE89762.1 - 0.025 14.3 9.3 1 9.2 4.0 2.5 2 1 0 2 2 2 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.5 EIE89762.1 - 0.036 14.0 4.0 0.036 14.0 2.8 2.5 2 1 0 2 2 2 0 Zinc ribbon domain RNHCP PF12647.2 EIE89762.1 - 0.059 13.2 6.8 0.15 11.8 1.4 2.2 1 1 1 2 2 2 0 RNHCP domain zinc_ribbon_2 PF13240.1 EIE89762.1 - 0.078 12.4 0.1 0.078 12.4 0.1 3.1 3 0 0 3 3 3 0 zinc-ribbon domain zf-UDP PF14569.1 EIE89762.1 - 0.097 12.4 3.2 0.12 12.0 1.8 1.4 1 1 0 1 1 1 0 Zinc-binding RING-finger zf-RING_3 PF14369.1 EIE89762.1 - 0.34 10.9 7.4 1.6 8.7 2.9 2.5 1 1 1 2 2 2 0 zinc-finger DZR PF12773.2 EIE89762.1 - 0.41 10.5 11.3 2.2 8.1 7.8 2.3 1 1 1 2 2 2 0 Double zinc ribbon SIR2 PF02146.12 EIE89762.1 - 0.43 10.2 2.3 0.63 9.7 1.6 1.4 1 0 0 1 1 1 0 Sir2 family HypA PF01155.14 EIE89762.1 - 0.45 10.2 8.7 1.4 8.6 6.0 1.9 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-ribbon_3 PF13248.1 EIE89762.1 - 0.53 9.5 8.3 0.59 9.4 3.3 2.4 2 1 0 2 2 2 0 zinc-ribbon domain Evr1_Alr PF04777.8 EIE89762.1 - 2.2 8.2 10.0 27 4.7 6.9 2.5 1 1 0 1 1 1 0 Erv1 / Alr family LIM PF00412.17 EIE89762.1 - 5.9 7.0 13.8 8.6 6.5 7.4 2.3 1 1 1 2 2 2 0 LIM domain Ribosomal_L37ae PF01780.14 EIE89762.1 - 8.5 6.3 6.7 17 5.3 2.8 2.1 1 1 1 2 2 2 0 Ribosomal L37ae protein family Hus1 PF04005.7 EIE89763.1 - 2.5e-20 72.6 0.0 2.7e-20 72.5 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein Pkinase PF00069.20 EIE89764.1 - 5.7e-26 91.2 0.1 5.8e-12 45.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIE89764.1 - 7.7e-06 25.1 0.2 2.7e-05 23.3 0.0 1.8 2 1 0 2 2 2 1 Protein tyrosine kinase Bac_surface_Ag PF01103.18 EIE89765.1 - 1.5e-44 152.7 1.0 1.8e-44 152.5 0.7 1.1 1 0 0 1 1 1 1 Surface antigen HMGL-like PF00682.14 EIE89767.1 - 1.5e-71 240.8 0.1 2.7e-71 239.9 0.0 1.4 1 0 0 1 1 1 1 HMGL-like UvrD_C PF13361.1 EIE89767.1 - 0.0013 18.2 0.1 0.92 8.8 0.0 2.3 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain MTHFR PF02219.12 EIE89768.1 - 2.5e-103 345.1 0.0 3.1e-103 344.8 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase AP_endonuc_2 PF01261.19 EIE89768.1 - 0.028 13.7 0.2 0.14 11.4 0.0 2.2 3 0 0 3 3 3 0 Xylose isomerase-like TIM barrel Lipase_3 PF01764.20 EIE89769.1 - 2.5e-21 75.7 0.0 3e-20 72.2 0.0 2.2 1 1 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 EIE89769.1 - 2.8e-05 23.6 0.0 0.00018 20.9 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.2 EIE89769.1 - 0.0057 16.5 0.0 0.053 13.3 0.0 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIE89769.1 - 0.042 13.5 0.0 0.064 13.0 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.8 EIE89769.1 - 0.046 13.2 0.0 0.076 12.5 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_9 PF10081.4 EIE89769.1 - 0.065 11.9 0.0 0.1 11.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta-hydrolase family DUF676 PF05057.9 EIE89769.1 - 0.07 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Ribosomal_L29e PF01779.12 EIE89770.1 - 2.2e-22 78.5 14.1 3.3e-22 78.0 9.8 1.3 1 0 0 1 1 1 1 Ribosomal L29e protein family Metallophos PF00149.23 EIE89772.1 - 2.8e-45 154.1 0.2 3.5e-45 153.8 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Aa_trans PF01490.13 EIE89773.1 - 2.2e-18 65.9 4.4 2.8e-18 65.5 3.0 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein F-box-like PF12937.2 EIE89775.1 - 1.7e-07 30.8 0.3 3.1e-07 30.0 0.2 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIE89775.1 - 8.6e-07 28.4 0.9 1.9e-06 27.3 0.7 1.5 1 0 0 1 1 1 1 F-box domain PRANC PF09372.5 EIE89775.1 - 0.081 12.8 2.0 0.17 11.8 0.1 2.2 2 0 0 2 2 2 0 PRANC domain Tim17 PF02466.14 EIE89776.1 - 1.1e-09 38.3 1.5 3.4e-07 30.3 0.1 2.6 3 0 0 3 3 3 2 Tim17/Tim22/Tim23/Pmp24 family Rax2 PF12768.2 EIE89777.1 - 1.1e-57 195.3 24.9 8.3e-43 146.6 0.1 5.2 2 1 2 5 5 5 4 Cortical protein marker for cell polarity SH3_9 PF14604.1 EIE89777.1 - 1.9e-08 33.7 0.0 4.8e-08 32.4 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EIE89777.1 - 2.5e-06 26.7 0.1 5.1e-06 25.7 0.1 1.6 1 0 0 1 1 1 1 SH3 domain IncA PF04156.9 EIE89777.1 - 0.16 11.5 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 IncA protein Kelch_1 PF01344.20 EIE89777.1 - 1.3 8.6 8.7 8.7 5.9 0.0 4.1 4 0 0 4 4 4 0 Kelch motif Plasmid_parti PF01672.11 EIE89778.1 - 0.18 12.2 5.9 0.4 11.1 1.3 2.3 2 0 0 2 2 2 0 Putative plasmid partition protein DUF2508 PF10704.4 EIE89778.1 - 0.2 11.8 2.9 0.28 11.3 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2508) BAR_2 PF10455.4 EIE89779.1 - 6.9e-52 176.1 7.2 1.2e-50 172.0 5.0 2.0 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 EIE89779.1 - 3.6e-22 79.0 3.9 6.2e-22 78.2 2.7 1.4 1 1 0 1 1 1 1 BAR domain DltD_C PF04914.7 EIE89779.1 - 0.0096 15.7 0.1 0.02 14.7 0.1 1.5 1 0 0 1 1 1 1 DltD C-terminal region rve_3 PF13683.1 EIE89779.1 - 0.0097 15.4 0.0 0.039 13.4 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain FANCI_HD2 PF14680.1 EIE89779.1 - 0.022 13.8 0.0 0.33 10.0 0.0 2.3 1 1 0 2 2 2 0 FANCI helical domain 2 ATG16 PF08614.6 EIE89779.1 - 0.8 9.5 9.3 0.49 10.1 0.1 2.3 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) MamL-1 PF09596.5 EIE89779.1 - 0.81 9.5 7.7 0.075 12.8 0.9 2.5 3 0 0 3 3 3 0 MamL-1 domain DUF4110 PF13422.1 EIE89779.1 - 0.87 9.4 5.9 0.16 11.7 0.8 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4110) Tom22 PF04281.8 EIE89780.1 - 0.02 14.4 0.9 0.028 13.9 0.6 1.3 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 Nucleoplasmin PF03066.10 EIE89780.1 - 0.03 13.8 2.1 0.044 13.2 1.5 1.2 1 0 0 1 1 1 0 Nucleoplasmin RXT2_N PF08595.6 EIE89780.1 - 0.043 13.6 1.4 0.062 13.1 1.0 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal Daxx PF03344.10 EIE89780.1 - 0.047 12.1 2.6 0.051 12.0 1.8 1.1 1 0 0 1 1 1 0 Daxx Family PBP1_TM PF14812.1 EIE89780.1 - 0.11 12.7 2.5 0.25 11.6 1.8 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CDC45 PF02724.9 EIE89780.1 - 0.17 9.9 1.5 0.22 9.4 1.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Retrotrans_gag PF03732.12 EIE89783.1 - 0.0071 16.3 0.0 0.0071 16.3 0.0 2.7 2 1 0 2 2 2 1 Retrotransposon gag protein SPARC_Ca_bdg PF10591.4 EIE89784.1 - 0.52 10.3 5.8 0.69 9.9 4.0 1.3 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region TT_ORF2 PF02957.10 EIE89784.1 - 0.88 10.2 4.8 1 10.0 3.3 1.1 1 0 0 1 1 1 0 TT viral ORF2 Rrp15p PF07890.7 EIE89784.1 - 2.7 8.0 13.5 3.5 7.6 9.3 1.3 1 0 0 1 1 1 0 Rrp15p POR_N PF01855.14 EIE89784.1 - 6.7 6.1 5.7 7.7 5.9 4.0 1.1 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Phage_Nu1 PF07471.7 EIE89785.1 - 0.072 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Phage DNA packaging protein Nu1 Fib_alpha PF08702.5 EIE89785.1 - 4.8 7.2 6.4 2.3 8.3 0.8 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Glyco_transf_49 PF13896.1 EIE89786.1 - 4.7e-42 144.2 0.1 7.1e-33 114.0 0.0 2.1 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glyco_tranf_2_2 PF10111.4 EIE89786.1 - 0.00019 20.6 0.1 0.00037 19.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.1 EIE89786.1 - 0.0079 16.4 1.4 0.011 15.9 0.1 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 2 Ribosomal_L1 PF00687.16 EIE89787.1 - 1.5e-51 174.8 1.1 1.8e-51 174.6 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family CIAPIN1 PF05093.8 EIE89787.1 - 0.13 12.3 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Metallophos PF00149.23 EIE89788.1 - 4.1e-43 147.1 0.6 5.6e-43 146.6 0.4 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase cwf21 PF08312.7 EIE89788.1 - 0.036 13.9 0.6 0.059 13.2 0.4 1.3 1 0 0 1 1 1 0 cwf21 domain SNF2_N PF00176.18 EIE89791.1 - 8.7e-82 274.2 0.6 8.7e-82 274.2 0.4 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain Bromodomain PF00439.20 EIE89791.1 - 3.4e-24 84.5 1.2 1.4e-23 82.5 0.7 2.3 1 1 1 2 2 2 1 Bromodomain HSA PF07529.8 EIE89791.1 - 8.5e-19 67.1 9.8 2.9e-18 65.4 6.8 2.0 1 0 0 1 1 1 1 HSA Helicase_C PF00271.26 EIE89791.1 - 4.3e-18 64.9 0.0 6.2e-17 61.2 0.0 3.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SnAC PF14619.1 EIE89791.1 - 8.2e-16 57.9 4.3 8.2e-16 57.9 3.0 3.6 2 0 0 2 2 2 1 Snf2-ATP coupling, chromatin remodelling complex QLQ PF08880.6 EIE89791.1 - 1.2e-12 47.0 4.1 2.6e-12 45.9 2.8 1.6 1 0 0 1 1 1 1 QLQ ResIII PF04851.10 EIE89791.1 - 2.5e-06 27.4 4.6 9.1e-06 25.6 0.0 3.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C2H2 PF00096.21 EIE89792.1 - 4.8e-13 48.6 4.9 4e-07 29.9 0.2 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIE89792.1 - 8.9e-10 38.2 10.2 1.3e-05 25.1 0.5 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EIE89792.1 - 1.2e-09 37.9 14.2 1e-06 28.6 0.1 3.5 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_6 PF13912.1 EIE89792.1 - 0.0066 16.3 0.5 1.7 8.6 0.0 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EIE89792.1 - 0.013 15.5 0.0 0.27 11.4 0.0 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 EIE89792.1 - 0.027 14.5 1.6 0.054 13.6 1.1 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.1 EIE89792.1 - 0.19 11.9 3.9 5.9 7.3 0.3 2.6 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-BED PF02892.10 EIE89792.1 - 0.38 10.5 1.7 2.3 8.0 0.2 2.2 1 1 1 2 2 2 0 BED zinc finger RRM_1 PF00076.17 EIE89793.1 - 1.5e-38 130.2 0.0 1.7e-19 69.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE89793.1 - 1.6e-34 117.6 0.0 1.5e-16 60.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE89793.1 - 4.2e-18 64.9 0.0 2.9e-10 39.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EIE89793.1 - 0.00023 20.8 0.0 0.14 11.9 0.0 2.5 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Band_3_cyto PF07565.8 EIE89793.1 - 0.14 11.6 6.7 0.22 11.0 4.6 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Limkain-b1 PF11608.3 EIE89793.1 - 0.15 11.8 1.9 0.82 9.4 0.0 2.7 2 1 1 3 3 2 0 Limkain b1 Spore_coat_CotO PF14153.1 EIE89793.1 - 0.18 11.2 12.4 0.23 10.8 8.6 1.2 1 0 0 1 1 1 0 Spore coat protein CotO CDC45 PF02724.9 EIE89793.1 - 0.18 9.7 10.6 0.21 9.5 7.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 EIE89793.1 - 0.58 8.5 18.5 0.84 8.0 12.8 1.1 1 0 0 1 1 1 0 Daxx Family Ycf1 PF05758.7 EIE89793.1 - 0.72 7.4 6.8 0.66 7.6 4.7 1.1 1 0 0 1 1 1 0 Ycf1 Nop14 PF04147.7 EIE89793.1 - 0.9 7.3 19.3 1.2 6.9 13.4 1.2 1 0 0 1 1 1 0 Nop14-like family Myc_N PF01056.13 EIE89793.1 - 3.2 6.8 13.3 4.8 6.2 9.2 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Sporozoite_P67 PF05642.6 EIE89793.1 - 4.1 5.1 9.0 5.7 4.6 6.2 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen GOLD_2 PF13897.1 EIE89793.1 - 4.1 7.6 7.2 11 6.2 5.0 1.8 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking NOA36 PF06524.7 EIE89793.1 - 7.1 5.7 12.4 13 4.9 8.6 1.4 1 0 0 1 1 1 0 NOA36 protein HSP90 PF00183.13 EIE89793.1 - 8.2 4.6 21.0 11 4.2 14.6 1.1 1 0 0 1 1 1 0 Hsp90 protein DUF1510 PF07423.6 EIE89793.1 - 9.1 5.5 21.6 13 5.0 15.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Striatin PF08232.7 EIE89794.1 - 0.0025 18.1 4.1 0.0025 18.1 2.9 2.2 1 1 1 2 2 2 1 Striatin family DUF4618 PF15397.1 EIE89794.1 - 0.011 15.0 3.8 0.011 15.0 2.6 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4618) SlyX PF04102.7 EIE89794.1 - 0.015 15.6 7.4 0.019 15.2 0.3 2.8 2 1 1 3 3 3 0 SlyX RmuC PF02646.11 EIE89794.1 - 0.016 14.0 6.0 0.049 12.4 0.3 2.2 1 1 0 2 2 2 0 RmuC family FliD_C PF07195.7 EIE89794.1 - 0.069 12.4 6.0 0.76 9.0 0.8 2.3 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus WXG100 PF06013.7 EIE89794.1 - 0.1 12.6 2.4 0.76 9.8 0.2 2.7 2 0 0 2 2 2 0 Proteins of 100 residues with WXG MscS_porin PF12795.2 EIE89794.1 - 0.16 11.2 11.2 2.7 7.2 2.6 2.4 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain Reo_sigmaC PF04582.7 EIE89794.1 - 0.34 10.0 5.7 0.3 10.2 1.9 1.8 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Retrotrans_gag PF03732.12 EIE89794.1 - 0.46 10.5 3.2 1.1 9.3 0.2 2.2 2 0 0 2 2 2 0 Retrotransposon gag protein AATF-Che1 PF13339.1 EIE89794.1 - 0.5 10.5 14.2 0.98 9.5 2.4 2.1 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor TPR_MLP1_2 PF07926.7 EIE89794.1 - 0.63 9.7 13.1 0.46 10.2 1.2 2.6 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein YscO PF07321.7 EIE89794.1 - 0.76 9.5 11.8 0.39 10.5 2.9 2.3 1 1 1 2 2 2 0 Type III secretion protein YscO DUF4349 PF14257.1 EIE89794.1 - 0.87 8.7 7.2 1.5 7.9 0.1 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF4349) DUF1284 PF06935.6 EIE89794.1 - 0.88 9.7 3.5 0.56 10.4 0.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1284) CorA PF01544.13 EIE89794.1 - 1 8.2 8.9 0.41 9.6 2.2 2.0 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein V_ATPase_I PF01496.14 EIE89794.1 - 1.1 7.0 12.7 0.12 10.2 2.6 1.9 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family IncA PF04156.9 EIE89794.1 - 2.1 7.8 14.6 7.4 6.1 4.0 2.1 1 1 1 2 2 2 0 IncA protein DUF2400 PF09674.5 EIE89794.1 - 2.5 7.7 6.3 8.7 5.9 0.3 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF2400) Halogen_Hydrol PF10112.4 EIE89794.1 - 3 7.2 7.2 1.2 8.4 1.8 2.2 1 1 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Bacillus_HBL PF05791.6 EIE89794.1 - 3 7.1 8.2 4.1 6.7 1.8 2.3 1 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF2203 PF09969.4 EIE89794.1 - 3.4 7.8 6.9 11 6.2 0.2 2.3 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF3571 PF12095.3 EIE89794.1 - 4.1 7.6 6.2 4 7.7 0.4 2.9 1 1 1 3 3 3 0 Protein of unknown function (DUF3571) DUF1664 PF07889.7 EIE89794.1 - 4.4 7.1 7.9 18 5.1 3.2 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Med4 PF10018.4 EIE89794.1 - 5.5 6.3 10.8 0.25 10.6 1.0 2.3 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF904 PF06005.7 EIE89794.1 - 8.5 6.7 10.7 0.43 10.9 1.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF904) Ead_Ea22 PF13935.1 EIE89794.1 - 9.1 6.6 8.4 30 4.9 3.7 2.8 1 1 1 2 2 2 0 Ead/Ea22-like protein DUF2638 PF10937.3 EIE89795.1 - 4e-08 34.2 3.9 2.9e-05 25.0 0.1 3.0 2 1 1 3 3 3 3 Protein of unknown function (DUF2638) Pkinase PF00069.20 EIE89796.1 - 7.7e-67 225.1 0.0 1.3e-66 224.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE89796.1 - 1.8e-34 119.0 0.0 3.3e-34 118.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.17 EIE89796.1 - 4e-19 68.0 29.5 6.3e-11 41.8 7.6 2.7 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) HR1 PF02185.11 EIE89796.1 - 2.8e-12 46.1 6.8 5.2e-06 26.0 0.5 2.5 2 0 0 2 2 2 2 Hr1 repeat Pkinase_C PF00433.19 EIE89796.1 - 1.5e-08 35.0 1.5 3.6e-08 33.8 0.1 2.3 2 0 0 2 2 2 1 Protein kinase C terminal domain RIB43A PF05914.7 EIE89796.1 - 3.3 6.2 10.9 0.015 13.9 1.2 1.7 2 0 0 2 2 2 0 RIB43A OMPdecase PF00215.19 EIE89797.1 - 7.9e-81 270.7 0.1 9.1e-81 270.5 0.1 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family DUF3159 PF11361.3 EIE89799.1 - 0.098 12.1 15.3 0.29 10.5 10.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3159) APOC4 PF15119.1 EIE89799.1 - 0.11 12.4 0.3 0.22 11.4 0.2 1.5 1 0 0 1 1 1 0 Apolipoprotein C4 IspA PF04279.10 EIE89799.1 - 1.4 8.8 15.5 0.099 12.6 4.8 2.2 1 1 0 2 2 2 0 Intracellular septation protein A MerC PF03203.9 EIE89799.1 - 2.1 8.7 10.8 6.2 7.2 3.7 2.7 1 1 1 2 2 2 0 MerC mercury resistance protein DUF3754 PF12576.3 EIE89799.1 - 6.8 6.3 6.7 19 4.8 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3754) DUF2109 PF09882.4 EIE89799.1 - 8.9 6.3 7.7 3.1 7.7 0.3 3.2 3 1 1 4 4 4 0 Predicted membrane protein (DUF2109) CPSF73-100_C PF11718.3 EIE89800.1 - 4.8e-43 147.0 0.3 8.9e-43 146.1 0.2 1.4 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 EIE89800.1 - 7.7e-34 116.3 0.0 2.5e-33 114.6 0.0 1.9 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B PF00753.22 EIE89800.1 - 6.7e-14 51.9 0.6 1.1e-13 51.2 0.4 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EIE89800.1 - 7.5e-12 45.1 1.3 1.6e-11 44.1 0.3 2.0 3 0 0 3 3 3 1 Beta-lactamase superfamily domain RMMBL PF07521.7 EIE89800.1 - 1.5e-10 40.6 0.1 3.5e-10 39.5 0.1 1.7 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 EIE89800.1 - 3.6e-09 36.5 0.1 8.4e-09 35.3 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DUF4116 PF13475.1 EIE89801.1 - 0.0039 16.6 0.0 0.0069 15.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4116) Rsm22 PF09243.5 EIE89802.1 - 7.3e-70 235.1 0.0 9.4e-70 234.7 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_31 PF13847.1 EIE89802.1 - 0.0001 21.9 0.0 0.00038 20.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIE89802.1 - 0.00037 20.2 0.0 0.00059 19.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIE89802.1 - 0.00076 19.8 0.0 0.0016 18.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIE89802.1 - 0.0022 18.4 0.0 0.0045 17.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIE89802.1 - 0.0044 17.4 0.0 0.0089 16.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIE89802.1 - 0.0052 17.3 0.0 0.0088 16.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain HSP70 PF00012.15 EIE89803.1 - 4.6e-08 31.4 0.0 2.5e-06 25.6 0.0 2.1 2 0 0 2 2 2 2 Hsp70 protein BcrAD_BadFG PF01869.15 EIE89803.1 - 0.039 13.2 0.1 0.094 11.9 0.0 1.7 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Ribosomal_L6 PF00347.18 EIE89804.1 - 1.1e-29 102.7 7.9 2e-17 63.4 2.6 2.0 2 0 0 2 2 2 2 Ribosomal protein L6 Pkinase PF00069.20 EIE89805.1 - 5.6e-51 173.1 0.0 1.6e-50 171.6 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE89805.1 - 7.1e-22 77.7 0.0 1.1e-21 77.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE89805.1 - 0.00022 20.3 0.0 0.0005 19.1 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EIE89805.1 - 0.15 11.7 0.0 0.63 9.7 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF1819 PF08849.6 EIE89806.1 - 0.017 14.5 0.3 0.025 13.9 0.2 1.3 1 0 0 1 1 1 0 Putative inner membrane protein (DUF1819) DUF1819 PF08849.6 EIE89807.1 - 0.017 14.5 0.3 0.025 13.9 0.2 1.3 1 0 0 1 1 1 0 Putative inner membrane protein (DUF1819) KASH PF10541.4 EIE89808.1 - 0.18 11.6 1.6 0.28 11.0 0.3 1.8 2 0 0 2 2 2 0 Nuclear envelope localisation domain DUF4244 PF14029.1 EIE89808.1 - 0.97 8.5 3.8 0.28 10.2 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4244) DctQ PF04290.7 EIE89808.1 - 2.1 8.0 6.7 2.5 7.8 4.6 1.1 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component DUF1917 PF08939.5 EIE89809.1 - 0.0069 16.1 1.2 0.0083 15.9 0.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1917) DUF4557 PF15101.1 EIE89809.1 - 0.25 11.1 2.0 0.29 10.9 1.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) RR_TM4-6 PF06459.7 EIE89809.1 - 0.28 11.0 7.8 0.31 10.8 5.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF262 PF03235.9 EIE89809.1 - 0.35 10.7 3.5 0.37 10.7 2.5 1.0 1 0 0 1 1 1 0 Protein of unknown function DUF262 Selenoprotein_S PF06936.6 EIE89809.1 - 0.36 10.3 9.5 0.4 10.1 6.6 1.1 1 0 0 1 1 1 0 Selenoprotein S (SelS) Vfa1 PF08432.5 EIE89809.1 - 0.39 10.7 14.0 0.47 10.4 9.7 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Pox_Ag35 PF03286.9 EIE89809.1 - 0.4 10.1 8.8 0.46 9.9 6.1 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein BTV_NS2 PF04514.7 EIE89809.1 - 0.46 9.3 10.8 0.52 9.1 7.5 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 U79_P34 PF03064.11 EIE89809.1 - 0.56 9.6 10.0 0.59 9.6 6.9 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF1510 PF07423.6 EIE89809.1 - 0.61 9.4 10.0 0.68 9.2 7.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Paf1 PF03985.8 EIE89809.1 - 0.73 8.5 10.2 0.82 8.3 7.1 1.0 1 0 0 1 1 1 0 Paf1 DUF2413 PF10310.4 EIE89809.1 - 0.97 8.1 8.7 1.1 7.9 6.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DDHD PF02862.12 EIE89809.1 - 1 9.1 4.5 1.1 8.9 3.1 1.1 1 0 0 1 1 1 0 DDHD domain RNase_H2-Ydr279 PF09468.5 EIE89809.1 - 1.1 8.3 9.2 1.3 8.1 6.3 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) NARP1 PF12569.3 EIE89809.1 - 1.3 7.7 13.0 1.5 7.5 9.0 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 HlyD PF00529.15 EIE89809.1 - 1.7 7.8 6.5 2.2 7.5 4.5 1.1 1 0 0 1 1 1 0 HlyD family secretion protein CDC45 PF02724.9 EIE89809.1 - 1.8 6.4 7.9 2 6.3 5.5 1.0 1 0 0 1 1 1 0 CDC45-like protein Ycf1 PF05758.7 EIE89809.1 - 2.4 5.7 7.1 2.5 5.6 4.9 1.0 1 0 0 1 1 1 0 Ycf1 RNA_pol_Rpc4 PF05132.9 EIE89809.1 - 3.7 7.5 7.5 5 7.1 5.2 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF1682 PF07946.9 EIE89809.1 - 3.9 6.2 14.9 4.5 6.0 10.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) PBP_sp32 PF07222.7 EIE89809.1 - 6.4 5.8 13.2 8.3 5.4 9.1 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Apelin PF15360.1 EIE89809.1 - 9.5 6.5 8.8 0.58 10.4 0.1 2.8 1 1 1 2 2 2 0 APJ endogenous ligand Myb_DNA-bind_6 PF13921.1 EIE89811.1 - 6.4e-05 22.9 0.1 0.0001 22.3 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EIE89811.1 - 0.095 12.7 0.4 0.21 11.6 0.3 1.7 1 1 0 1 1 1 0 Myb-like DNA-binding domain MFS_1 PF07690.11 EIE89812.1 - 2.3e-28 98.9 45.8 2.6e-20 72.4 11.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIE89812.1 - 1.8e-08 33.4 34.5 0.0016 17.1 6.6 3.3 2 2 1 3 3 3 3 Sugar (and other) transporter MFS_2 PF13347.1 EIE89812.1 - 3.3e-08 32.3 24.4 4.7e-08 31.8 14.7 2.1 1 1 1 2 2 2 2 MFS/sugar transport protein RVT_1 PF00078.22 EIE89814.1 - 6.8e-08 32.1 0.0 1.4e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Inhibitor_I67 PF11405.3 EIE89815.1 - 0.016 15.2 3.0 0.041 13.9 2.1 1.7 1 0 0 1 1 1 0 Bromelain inhibitor VI UPF0150 PF03681.10 EIE89815.1 - 0.017 14.7 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0150) MFS_1 PF07690.11 EIE89816.1 - 1e-28 100.1 45.3 1.2e-20 73.5 8.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIE89816.1 - 9.2e-09 34.3 33.5 0.0032 16.1 7.7 3.3 2 2 1 3 3 3 3 Sugar (and other) transporter MFS_2 PF13347.1 EIE89816.1 - 1.5e-07 30.2 24.2 1.7e-07 30.0 14.5 2.0 1 1 1 2 2 2 2 MFS/sugar transport protein zf-RVT PF13966.1 EIE89817.1 - 6.1e-05 23.2 0.8 6.1e-05 23.2 0.5 1.9 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase DDE_3 PF13358.1 EIE89818.1 - 0.0099 15.6 0.1 0.016 14.9 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Lar_restr_allev PF14354.1 EIE89819.1 - 0.13 12.6 0.1 2.1 8.6 0.0 2.3 2 0 0 2 2 2 0 Restriction alleviation protein Lar DUF3783 PF12646.2 EIE89820.1 - 0.023 14.4 0.4 3.2 7.5 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) AARP2CN PF08142.7 EIE89820.1 - 0.039 13.4 0.3 0.94 9.0 0.0 2.0 1 1 1 2 2 2 0 AARP2CN (NUC121) domain Mvb12 PF09452.5 EIE89820.1 - 0.066 13.3 0.0 13 6.0 0.0 2.0 1 1 1 2 2 2 0 ESCRT-I subunit Mvb12 RVT_1 PF00078.22 EIE89821.1 - 6.3e-39 133.5 0.0 1.3e-38 132.4 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.18 EIE89822.1 - 3.6e-05 23.4 11.2 0.0033 17.2 0.9 2.3 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 EIE89822.1 - 0.0033 17.0 5.7 0.0075 15.9 0.3 2.4 2 0 0 2 2 2 1 Zinc knuckle RRM_1 PF00076.17 EIE89822.1 - 0.046 13.3 0.0 0.14 11.7 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC_3 PF13917.1 EIE89822.1 - 2.5 7.8 7.9 2.2 8.0 0.1 2.3 1 1 1 2 2 2 0 Zinc knuckle Zn_ribbon_2 PF12674.2 EIE89822.1 - 6.3 7.2 7.6 31 5.0 1.3 2.6 1 1 1 2 2 2 0 Putative zinc ribbon domain zf-RVT PF13966.1 EIE89823.1 - 2.2e-05 24.6 0.8 4.7e-05 23.6 0.5 1.6 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Abhydrolase_5 PF12695.2 EIE89825.1 - 6.9e-09 35.6 0.1 1e-08 35.0 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIE89825.1 - 2.9e-06 27.3 0.2 3.6e-06 27.0 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EIE89825.1 - 0.0022 17.4 0.0 0.0022 17.4 0.0 1.1 1 0 0 1 1 1 1 Putative esterase DUF2048 PF09752.4 EIE89825.1 - 0.0031 16.4 0.3 0.0034 16.3 0.2 1.3 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2048) DLH PF01738.13 EIE89825.1 - 0.0039 16.4 0.0 0.0056 15.9 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family GSHPx PF00255.14 EIE89826.1 - 1.4e-41 140.1 1.0 1.8e-41 139.8 0.7 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 EIE89826.1 - 5.1e-08 32.6 0.1 1.1e-07 31.6 0.1 1.7 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EIE89826.1 - 8.2e-07 28.6 0.1 2.3e-06 27.2 0.0 1.7 1 1 0 1 1 1 1 Redoxin DUF4174 PF13778.1 EIE89826.1 - 0.061 13.4 0.0 0.31 11.1 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4174) GHMP_kinases_N PF00288.21 EIE89828.1 - 3.8e-13 49.2 0.6 9.1e-13 48.0 0.4 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EIE89828.1 - 0.0042 17.2 0.0 0.014 15.5 0.0 1.9 2 0 0 2 2 2 1 GHMP kinases C terminal HOASN PF14515.1 EIE89828.1 - 0.073 13.4 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 Haem-oxygenase-associated N-terminal helices CDC50 PF03381.10 EIE89829.1 - 1.4e-90 303.2 1.3 1.7e-90 302.9 0.9 1.0 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family zf-DHHC PF01529.15 EIE89830.1 - 1.4e-19 70.1 5.6 1.7e-19 69.8 3.9 1.1 1 0 0 1 1 1 1 DHHC palmitoyltransferase PsbI PF02532.9 EIE89830.1 - 7.3 6.2 7.5 13 5.4 5.2 1.3 1 0 0 1 1 1 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) Tim17 PF02466.14 EIE89831.1 - 2.1e-23 82.7 10.1 2.8e-23 82.3 7.0 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family SIR2 PF02146.12 EIE89832.1 - 2.4e-60 203.3 0.0 2.4e-60 203.3 0.0 2.0 2 0 0 2 2 2 1 Sir2 family DUF592 PF04574.8 EIE89832.1 - 0.00026 20.6 0.7 0.00026 20.6 0.5 3.5 2 2 1 3 3 3 1 Protein of unknown function (DUF592) Borrelia_P83 PF05262.6 EIE89832.1 - 0.0023 16.2 13.2 0.0023 16.2 9.1 2.2 2 0 0 2 2 2 1 Borrelia P83/100 protein TPP_enzyme_M PF00205.17 EIE89832.1 - 0.073 12.8 0.0 0.9 9.2 0.0 2.2 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Arm PF00514.18 EIE89833.1 - 0.024 14.4 12.3 0.45 10.4 0.0 6.0 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat HEAT PF02985.17 EIE89833.1 - 0.058 13.5 0.1 0.91 9.7 0.0 3.0 2 0 0 2 2 2 0 HEAT repeat DUF1840 PF08895.6 EIE89833.1 - 0.73 9.8 2.9 1.2 9.1 0.0 2.8 4 0 0 4 4 4 0 Domain of unknown function (DUF1840) HTH_Tnp_Tc3_2 PF01498.13 EIE89835.1 - 6.8e-08 32.4 0.4 1.3e-07 31.6 0.3 1.4 1 0 0 1 1 1 1 Transposase PUL PF08324.6 EIE89835.1 - 0.15 10.8 0.5 7.2 5.3 0.0 2.2 1 1 1 2 2 2 0 PUL domain DDE_3 PF13358.1 EIE89836.1 - 2.4e-11 43.5 0.2 3.4e-11 43.0 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_IS1595 PF12762.2 EIE89837.1 - 8.3e-05 22.4 1.4 0.00014 21.7 0.6 1.7 1 1 0 1 1 1 1 ISXO2-like transposase domain Fibrinogen_aC PF12160.3 EIE89837.1 - 0.016 14.6 0.2 0.03 13.7 0.2 1.5 1 0 0 1 1 1 0 Fibrinogen alpha C domain Transposase_21 PF02992.9 EIE89839.1 - 6.8e-22 77.6 0.0 1.5e-21 76.5 0.0 1.5 1 0 0 1 1 1 1 Transposase family tnp2 DUF1258 PF06869.7 EIE89839.1 - 0.0025 16.9 0.0 0.0041 16.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) Med15 PF09606.5 EIE89840.1 - 0.028 12.6 12.5 0.04 12.1 8.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal FlgM PF04316.8 EIE89840.1 - 2.2 8.2 5.1 13 5.8 2.9 2.3 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM Transposase_21 PF02992.9 EIE89841.1 - 2e-21 76.1 0.0 4.1e-21 75.1 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 DUF1258 PF06869.7 EIE89841.1 - 0.0053 15.8 0.0 0.011 14.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) FKBP_N PF01346.13 EIE89842.1 - 0.0098 15.9 1.5 0.0098 15.9 1.1 1.5 2 0 0 2 2 2 1 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase LAG1-DNAbind PF09271.6 EIE89842.1 - 0.028 14.8 0.3 0.057 13.9 0.2 1.5 1 0 0 1 1 1 0 LAG1, DNA binding HTH_37 PF13744.1 EIE89842.1 - 0.77 9.5 6.0 16 5.3 3.3 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain RRF_GI PF12614.3 EIE89843.1 - 0.02 14.7 0.2 0.021 14.6 0.1 1.2 1 0 0 1 1 1 0 Ribosome recycling factor HTH_Tnp_Tc3_2 PF01498.13 EIE89844.1 - 6e-09 35.8 0.5 8.4e-09 35.3 0.3 1.2 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.1 EIE89844.1 - 0.0044 16.7 0.0 0.0058 16.3 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EIE89846.1 - 8.5e-10 38.5 0.6 6.5e-06 25.9 0.5 2.8 2 1 1 3 3 3 2 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE89846.1 - 1.3e-08 34.7 1.0 2.3e-08 33.9 0.6 1.5 1 1 0 1 1 1 1 Transposase MULE PF10551.4 EIE89847.1 - 8.3e-08 32.3 0.1 1.6e-07 31.3 0.1 1.5 1 0 0 1 1 1 1 MULE transposase domain Vps5 PF09325.5 EIE89847.1 - 0.091 12.0 3.9 0.055 12.7 0.5 2.0 2 1 0 2 2 2 0 Vps5 C terminal like Transposase_21 PF02992.9 EIE89848.1 - 5.3e-20 71.4 1.1 6e-20 71.2 0.0 1.5 2 0 0 2 2 2 1 Transposase family tnp2 DDE_3 PF13358.1 EIE89849.1 - 2e-21 76.2 0.3 3.5e-21 75.4 0.2 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE89849.1 - 4.6e-15 55.4 0.4 1.1e-14 54.2 0.3 1.7 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.1 EIE89849.1 - 3.9e-06 27.5 0.0 0.00038 21.1 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_33 PF13592.1 EIE89849.1 - 0.00014 21.3 0.1 0.00058 19.3 0.0 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_21 PF13276.1 EIE89849.1 - 0.0023 17.8 0.0 0.039 13.9 0.0 2.5 2 0 0 2 2 2 1 HTH-like domain HTH_29 PF13551.1 EIE89849.1 - 0.0047 17.0 0.1 0.019 15.1 0.0 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HMG_box_2 PF09011.5 EIE89849.1 - 0.038 14.3 1.7 0.083 13.2 0.3 2.1 2 0 0 2 2 2 0 HMG-box domain DDE_Tnp_IS66 PF03050.9 EIE89849.1 - 0.039 13.1 1.3 4.7 6.3 0.1 3.0 2 1 0 3 3 3 0 Transposase IS66 family rve PF00665.21 EIE89849.1 - 0.056 13.5 0.0 0.18 11.8 0.0 2.0 1 1 0 1 1 1 0 Integrase core domain HMG_box PF00505.14 EIE89849.1 - 0.067 13.4 1.2 0.29 11.4 0.5 2.3 2 0 0 2 2 2 0 HMG (high mobility group) box HTH_Tnp_Tc3_2 PF01498.13 EIE89850.1 - 1e-08 35.0 0.1 2.3e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.1 EIE89850.1 - 2.7e-06 27.1 0.0 4.9e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_ISAZ013 PF07592.6 EIE89850.1 - 0.061 12.0 0.0 0.081 11.6 0.0 1.2 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain TPR_MLP1_2 PF07926.7 EIE89851.1 - 2e-05 24.3 0.3 2.9e-05 23.8 0.2 1.2 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.7 EIE89851.1 - 0.0063 15.7 1.4 0.0089 15.2 0.9 1.2 1 0 0 1 1 1 1 Reovirus sigma C capsid protein DUF972 PF06156.8 EIE89851.1 - 0.0098 16.2 0.1 0.017 15.4 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF972) DivIVA PF05103.8 EIE89851.1 - 0.016 15.2 0.0 0.03 14.3 0.0 1.5 1 0 0 1 1 1 0 DivIVA protein HALZ PF02183.13 EIE89851.1 - 0.04 13.6 0.1 0.095 12.4 0.1 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper SlyX PF04102.7 EIE89851.1 - 0.085 13.2 0.2 0.24 11.7 0.1 1.8 1 0 0 1 1 1 0 SlyX Phage_GP20 PF06810.6 EIE89851.1 - 0.085 12.2 0.4 0.13 11.7 0.3 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 DivIC PF04977.10 EIE89851.1 - 0.1 12.0 1.6 0.21 11.1 0.9 1.7 1 1 0 1 1 1 0 Septum formation initiator DUF3446 PF11928.3 EIE89851.1 - 0.81 9.9 10.5 6.2 7.0 6.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) HTH_Tnp_Tc3_2 PF01498.13 EIE89853.1 - 2.9e-07 30.4 1.5 4.7e-06 26.5 0.4 2.2 2 0 0 2 2 2 1 Transposase HTH_11 PF08279.7 EIE89853.1 - 0.00023 20.7 0.1 0.00056 19.4 0.0 1.6 2 0 0 2 2 1 1 HTH domain HTH_IclR PF09339.5 EIE89853.1 - 0.00024 20.6 0.0 0.00051 19.5 0.0 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_23 PF13384.1 EIE89853.1 - 0.00026 20.5 0.0 0.00064 19.2 0.0 1.6 2 0 0 2 2 2 1 Homeodomain-like domain HTH_7 PF02796.10 EIE89853.1 - 0.0015 18.3 0.1 0.083 12.7 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_38 PF13936.1 EIE89853.1 - 0.0074 15.8 0.0 0.016 14.7 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Crp_2 PF13545.1 EIE89853.1 - 0.008 15.9 0.0 0.027 14.2 0.0 1.8 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_29 PF13551.1 EIE89853.1 - 0.0092 16.1 0.0 0.017 15.2 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn helix HTH_17 PF12728.2 EIE89853.1 - 0.011 15.9 0.0 0.02 15.1 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4_2 PF08281.7 EIE89853.1 - 0.013 14.9 0.0 0.028 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 Sigma70_r4 PF04545.11 EIE89853.1 - 0.014 14.7 0.0 0.025 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_24 PF13412.1 EIE89853.1 - 0.016 14.5 0.0 0.038 13.3 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding GerE PF00196.14 EIE89853.1 - 0.019 14.2 0.0 0.035 13.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family HTH_36 PF13730.1 EIE89853.1 - 0.019 15.0 0.1 0.29 11.3 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain UPF0122 PF04297.9 EIE89853.1 - 0.024 14.6 0.0 0.04 13.9 0.0 1.3 1 0 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like MarR_2 PF12802.2 EIE89853.1 - 0.033 13.8 0.0 0.065 12.9 0.0 1.4 1 0 0 1 1 1 0 MarR family Terminase_5 PF06056.7 EIE89853.1 - 0.034 13.6 0.0 0.058 12.9 0.0 1.3 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) HTH_AsnC-type PF13404.1 EIE89853.1 - 0.034 13.6 0.0 0.063 12.8 0.0 1.4 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_22 PF13309.1 EIE89853.1 - 0.06 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 HTH domain HTH_6 PF01418.12 EIE89853.1 - 0.066 12.9 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family HTH_Tnp_4 PF13613.1 EIE89853.1 - 0.084 12.4 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease DUF603 PF04645.7 EIE89853.1 - 0.094 12.6 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF603 TetR_N PF00440.18 EIE89853.1 - 0.11 12.1 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family HTH_31 PF13560.1 EIE89853.1 - 0.12 12.6 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain DUF658 PF04936.7 EIE89853.1 - 0.13 12.0 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF658) Retrotrans_gag PF03732.12 EIE89855.1 - 4.7e-07 29.7 0.0 1e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein HTH_Tnp_Tc3_2 PF01498.13 EIE89856.1 - 1.4e-15 57.0 0.2 2.2e-15 56.4 0.2 1.3 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.1 EIE89856.1 - 0.022 14.5 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease HTH_29 PF13551.1 EIE89856.1 - 0.023 14.8 0.1 0.044 13.9 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn helix HTH_21 PF13276.1 EIE89856.1 - 0.13 12.2 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 HTH-like domain DDE_3 PF13358.1 EIE89857.1 - 1.1e-14 54.4 0.0 2.5e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE89857.1 - 0.00018 21.5 1.8 0.00018 21.5 1.2 2.1 2 1 0 2 2 2 1 Transposase FAM70 PF14967.1 EIE89857.1 - 0.12 11.6 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 FAM70 protein Septin PF00735.13 EIE89860.1 - 2.7e-109 364.5 0.0 3e-109 364.4 0.0 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EIE89860.1 - 3.8e-06 26.8 0.0 9.2e-06 25.6 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EIE89860.1 - 0.00036 20.3 0.1 0.89 9.3 0.0 2.3 1 1 1 2 2 2 2 Dynamin family AIG1 PF04548.11 EIE89860.1 - 0.0044 16.1 0.1 0.012 14.7 0.1 1.7 2 1 0 2 2 2 1 AIG1 family GTP_EFTU PF00009.22 EIE89860.1 - 0.013 14.8 0.1 0.056 12.8 0.0 1.8 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.13 EIE89860.1 - 0.026 14.0 0.1 0.06 12.8 0.1 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF258 PF03193.11 EIE89860.1 - 0.026 13.6 0.3 0.11 11.6 0.2 1.9 1 1 0 1 1 1 0 Protein of unknown function, DUF258 T2SE PF00437.15 EIE89860.1 - 0.051 12.4 0.0 0.078 11.8 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein MobB PF03205.9 EIE89860.1 - 0.052 13.2 0.0 0.08 12.6 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 EIE89860.1 - 0.054 13.6 0.0 0.12 12.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain Miro PF08477.8 EIE89860.1 - 0.08 13.4 0.0 0.17 12.4 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein AAA_17 PF13207.1 EIE89860.1 - 0.14 12.9 2.0 0.48 11.2 1.4 2.2 1 1 0 1 1 1 0 AAA domain Ras PF00071.17 EIE89861.1 - 7.5e-30 103.4 0.2 4.3e-28 97.7 0.1 2.1 1 1 0 1 1 1 1 Ras family Arf PF00025.16 EIE89861.1 - 1.3e-05 24.5 0.4 0.0028 16.8 0.0 2.1 1 1 1 2 2 2 2 ADP-ribosylation factor family Miro PF08477.8 EIE89861.1 - 0.00015 22.2 0.1 0.0015 18.9 0.0 2.3 1 1 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 EIE89861.1 - 0.0012 18.2 0.0 0.0057 16.1 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Carn_acyltransf PF00755.15 EIE89862.1 - 8.3e-165 549.2 0.6 1.1e-164 548.8 0.4 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Peptidase_C14 PF00656.17 EIE89863.1 - 4.6e-70 236.1 0.0 8.3e-70 235.2 0.0 1.4 1 0 0 1 1 1 1 Caspase domain Snf7 PF03357.16 EIE89863.1 - 3.4e-42 143.7 22.8 6.2e-42 142.8 15.8 1.4 1 0 0 1 1 1 1 Snf7 KRBA1 PF15287.1 EIE89863.1 - 0.81 9.0 0.0 0.81 9.0 0.0 2.4 3 0 0 3 3 3 0 KRBA1 family repeat Hydrolase PF00702.21 EIE89864.1 - 5.5e-16 59.6 0.0 1.4e-15 58.2 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EIE89864.1 - 1.6e-11 44.7 0.5 5.6e-11 42.9 0.3 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EIE89864.1 - 4.2e-09 35.7 0.0 8.5e-09 34.7 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 EIE89864.1 - 9.5e-07 28.6 0.0 5.1e-06 26.3 0.0 2.1 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EIE89864.1 - 4.1e-05 23.2 0.1 0.00031 20.4 0.0 2.5 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase DDE_3 PF13358.1 EIE89865.1 - 9.2e-07 28.7 0.1 1.9e-06 27.7 0.0 1.4 1 1 0 1 1 1 1 DDE superfamily endonuclease RNA_pol PF00940.14 EIE89866.1 - 8.2e-160 531.7 0.0 1.2e-159 531.1 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 EIE89866.1 - 9.3e-86 287.9 0.5 2.4e-84 283.3 0.1 2.3 2 0 0 2 2 2 1 DNA-directed RNA polymerase N-terminal PPR_2 PF13041.1 EIE89866.1 - 3.8e-08 33.1 2.3 1.1e-06 28.4 0.2 2.5 2 0 0 2 2 2 1 PPR repeat family PPR_3 PF13812.1 EIE89866.1 - 0.0013 18.8 0.1 16 6.0 0.0 4.1 4 0 0 4 4 4 2 Pentatricopeptide repeat domain PPR PF01535.15 EIE89866.1 - 0.11 12.5 1.3 7.9 6.6 0.1 3.5 3 1 0 3 3 3 0 PPR repeat CHZ PF09649.5 EIE89869.1 - 2.1e-11 42.8 0.1 2.1e-11 42.8 0.1 2.7 3 0 0 3 3 1 1 Histone chaperone domain CHZ DUF3807 PF12720.2 EIE89869.1 - 0.0077 16.4 19.4 0.0093 16.1 13.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3807) PAXIP1_C PF15364.1 EIE89869.1 - 0.017 15.0 17.2 0.025 14.5 11.9 1.4 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein BUD22 PF09073.5 EIE89869.1 - 0.086 11.8 27.2 0.11 11.5 18.8 1.1 1 0 0 1 1 1 0 BUD22 SRP-alpha_N PF04086.8 EIE89869.1 - 0.41 9.9 20.8 0.52 9.6 14.4 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal MIP-T3 PF10243.4 EIE89869.1 - 0.55 8.6 28.1 0.59 8.5 19.5 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Daxx PF03344.10 EIE89869.1 - 0.7 8.2 23.8 0.72 8.2 16.5 1.0 1 0 0 1 1 1 0 Daxx Family DUF572 PF04502.8 EIE89869.1 - 0.91 8.6 20.3 1 8.5 14.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) BSP_II PF05432.6 EIE89869.1 - 1.3 8.2 26.7 2.3 7.3 18.4 1.5 1 1 0 1 1 1 0 Bone sialoprotein II (BSP-II) Tim54 PF11711.3 EIE89869.1 - 1.5 7.3 14.0 1.6 7.2 9.7 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF3827 PF12877.2 EIE89869.1 - 1.7 6.6 14.6 2 6.3 10.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) GAGA_bind PF06217.7 EIE89869.1 - 2 8.2 11.5 2.8 7.8 8.0 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Rtf2 PF04641.7 EIE89869.1 - 2.2 7.4 19.1 3.2 6.8 13.3 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger TFIIF_alpha PF05793.7 EIE89869.1 - 2.3 6.5 35.5 3.6 5.8 24.6 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC27 PF09507.5 EIE89869.1 - 2.6 7.1 29.9 3.1 6.9 20.7 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Neur_chan_memb PF02932.11 EIE89869.1 - 3 7.6 8.5 3.2 7.5 5.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FLO_LFY PF01698.11 EIE89869.1 - 3.2 6.5 16.5 3.8 6.2 11.5 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Sec62 PF03839.11 EIE89869.1 - 3.3 7.0 20.3 4 6.7 14.0 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 DNA_pol_phi PF04931.8 EIE89869.1 - 3.7 5.2 27.7 4.6 4.8 19.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF2890 PF11081.3 EIE89869.1 - 4.7 7.2 23.6 6.1 6.8 16.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) HGTP_anticodon2 PF12745.2 EIE89869.1 - 5.2 6.1 16.4 7 5.7 11.4 1.1 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs CENP-T PF15511.1 EIE89869.1 - 6.2 5.9 23.2 1.2 8.2 13.8 1.5 1 1 1 2 2 2 0 Centromere kinetochore component CENP-T Dsh_C PF12316.3 EIE89869.1 - 6.9 6.7 9.4 8.8 6.3 6.5 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal DUF966 PF06136.8 EIE89869.1 - 7.2 5.9 17.3 7.9 5.7 12.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) BTV_NS2 PF04514.7 EIE89869.1 - 7.5 5.3 18.1 10 4.8 12.6 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 RR_TM4-6 PF06459.7 EIE89869.1 - 7.7 6.3 21.3 11 5.8 14.7 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Hid1 PF12722.2 EIE89869.1 - 8.9 3.8 14.3 9.2 3.8 9.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Dicty_REP PF05086.7 EIE89869.1 - 9.2 3.8 12.0 10 3.6 8.3 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Paf1 PF03985.8 EIE89869.1 - 9.3 4.8 28.1 11 4.5 19.5 1.1 1 0 0 1 1 1 0 Paf1 Sipho_Gp157 PF05565.6 EIE89870.1 - 0.086 12.4 7.1 0.15 11.6 4.9 1.3 1 0 0 1 1 1 0 Siphovirus Gp157 DUF3293 PF11697.3 EIE89870.1 - 0.43 10.7 1.9 0.54 10.4 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3293) SRPRB PF09439.5 EIE89870.1 - 5.6 6.1 8.4 5.2 6.2 1.5 2.2 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit DUF3417 PF11897.3 EIE89870.1 - 6.6 6.7 7.2 7.9 6.4 0.1 2.8 1 1 1 3 3 3 0 Protein of unknown function (DUF3417) CENP-H PF05837.7 EIE89870.1 - 9.4 6.4 16.2 0.78 9.9 6.3 2.5 2 1 0 2 2 2 0 Centromere protein H (CENP-H) ALG3 PF05208.8 EIE89871.1 - 9.3e-95 317.9 12.9 1e-94 317.8 8.9 1.0 1 0 0 1 1 1 1 ALG3 protein ParA PF10609.4 EIE89872.1 - 8.1e-36 121.7 0.0 1.6e-35 120.8 0.0 1.5 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EIE89872.1 - 1e-12 47.9 0.0 1.5e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.10 EIE89872.1 - 0.00014 21.0 0.1 0.00046 19.3 0.0 1.8 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_31 PF13614.1 EIE89872.1 - 0.0015 18.4 0.0 0.0087 16.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EIE89872.1 - 0.003 16.7 0.0 0.0053 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 EIE89872.1 - 0.0037 16.7 0.0 0.0059 16.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain MipZ PF09140.6 EIE89872.1 - 0.0093 15.0 0.0 0.02 14.0 0.0 1.5 1 1 0 1 1 1 1 ATPase MipZ AAA_26 PF13500.1 EIE89872.1 - 0.015 14.9 0.0 0.4 10.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain Fer4_NifH PF00142.13 EIE89872.1 - 0.046 12.8 0.0 1.5 7.9 0.0 2.4 2 1 1 3 3 3 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family TF_Zn_Ribbon PF08271.7 EIE89872.1 - 0.046 13.0 0.1 0.12 11.7 0.1 1.7 1 0 0 1 1 1 0 TFIIB zinc-binding AAA_16 PF13191.1 EIE89872.1 - 0.074 13.0 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain ArgK PF03308.11 EIE89872.1 - 0.11 11.2 0.1 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 ArgK protein SNARE PF05739.14 EIE89873.1 - 1.7e-10 40.4 2.4 1.9e-10 40.2 1.7 1.1 1 0 0 1 1 1 1 SNARE domain TBCA PF02970.11 EIE89873.1 - 0.069 13.2 0.6 0.086 12.9 0.4 1.3 1 1 0 1 1 1 0 Tubulin binding cofactor A SlyX PF04102.7 EIE89873.1 - 0.1 13.0 1.9 9.5 6.6 0.1 2.1 1 1 1 2 2 2 0 SlyX Pkinase PF00069.20 EIE89874.1 - 3.7e-67 226.2 0.0 5.3e-67 225.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE89874.1 - 2.4e-29 102.1 0.0 3.4e-29 101.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EIE89874.1 - 2.2e-11 44.1 4.3 2.2e-11 44.1 3.0 2.0 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 EIE89874.1 - 5.5e-05 22.2 0.0 8.1e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EIE89874.1 - 0.094 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 EIE89874.1 - 0.12 11.4 0.0 0.23 10.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PDEase_I PF00233.14 EIE89875.1 - 2.7e-53 181.1 3.3 1e-52 179.2 2.3 1.8 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase BTD PF09270.5 EIE89876.1 - 5.9e-26 91.1 0.5 3.7e-16 59.2 0.0 3.2 2 1 0 2 2 2 2 Beta-trefoil DNA-binding domain LAG1-DNAbind PF09271.6 EIE89876.1 - 1.7e-21 77.1 0.6 3e-21 76.3 0.4 1.4 1 0 0 1 1 1 1 LAG1, DNA binding TIG PF01833.19 EIE89876.1 - 5.7e-05 23.0 0.0 0.0002 21.3 0.0 2.0 1 0 0 1 1 1 1 IPT/TIG domain TFIIA PF03153.8 EIE89877.1 - 3 7.6 28.4 4 7.2 19.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Syntaxin PF00804.20 EIE89878.1 - 0.67 10.1 3.3 2.9 8.1 2.3 1.8 1 1 0 1 1 1 0 Syntaxin NDUF_B12 PF08122.7 EIE89879.1 - 1.3e-20 72.8 0.7 1.5e-20 72.6 0.5 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family Acetyltransf_1 PF00583.19 EIE89880.1 - 1e-06 28.6 0.0 1.9e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EIE89880.1 - 1.4e-06 28.4 0.0 0.0028 17.7 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EIE89880.1 - 5.8e-05 23.1 0.0 0.00052 20.1 0.0 2.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EIE89880.1 - 0.0031 17.7 1.0 0.013 15.6 0.2 2.3 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Thiolase_N PF00108.18 EIE89881.1 - 1.6e-97 325.6 0.1 2.1e-97 325.2 0.0 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EIE89881.1 - 5.7e-42 142.0 0.7 5.7e-42 142.0 0.5 1.6 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EIE89881.1 - 3e-05 23.6 2.1 3e-05 23.6 1.5 2.6 2 1 1 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 EIE89881.1 - 0.028 14.0 1.9 2.3 7.9 0.1 2.7 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Glyco_transf_20 PF00982.16 EIE89882.1 - 1.3e-162 541.5 0.0 1.8e-162 541.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EIE89882.1 - 2.7e-80 268.6 0.0 5.1e-80 267.7 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase Glyco_trans_1_4 PF13692.1 EIE89882.1 - 0.043 13.9 0.0 0.23 11.6 0.0 2.4 2 1 0 2 2 2 0 Glycosyl transferases group 1 HAD PF12710.2 EIE89882.1 - 0.53 10.4 2.0 8 6.5 1.4 2.6 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Voldacs PF03517.8 EIE89883.1 - 8.2e-14 51.5 0.0 1.1e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling Sulfotransfer_3 PF13469.1 EIE89884.1 - 0.00073 20.5 0.0 0.0022 18.9 0.0 1.8 1 1 0 1 1 1 1 Sulfotransferase family DDE_3 PF13358.1 EIE89885.1 - 0.0072 16.0 0.1 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease cIII PF08134.6 EIE89885.1 - 0.59 9.7 2.4 0.47 10.1 0.2 1.8 2 0 0 2 2 2 0 cIII protein family zf-CCHC_3 PF13917.1 EIE89886.1 - 0.079 12.7 6.9 7.2 6.4 0.0 2.3 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC PF00098.18 EIE89886.1 - 0.13 12.2 11.6 0.16 11.9 0.2 2.2 2 0 0 2 2 2 0 Zinc knuckle RVT_1 PF00078.22 EIE89887.1 - 2e-16 60.0 0.0 4.4e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.18 EIE89888.1 - 0.0017 18.2 0.5 0.0017 18.2 0.3 3.3 3 0 0 3 3 3 2 Zinc knuckle SOUL PF04832.7 EIE89888.1 - 0.039 13.4 0.1 0.1 12.1 0.1 1.6 2 0 0 2 2 2 0 SOUL heme-binding protein DnaJ_CXXCXGXG PF00684.14 EIE89888.1 - 0.16 12.0 7.8 5.1 7.2 0.1 2.6 2 0 0 2 2 2 0 DnaJ central domain Sulfotransfer_3 PF13469.1 EIE89889.1 - 0.00089 20.2 0.0 0.0029 18.5 0.0 1.8 1 1 0 1 1 1 1 Sulfotransferase family Dehydratase_SU PF02287.10 EIE89889.1 - 0.097 12.4 0.1 0.16 11.6 0.1 1.3 1 0 0 1 1 1 0 Dehydratase small subunit Fork_head PF00250.13 EIE89890.1 - 1.4e-35 121.1 0.4 3.5e-35 119.9 0.2 1.7 1 0 0 1 1 1 1 Fork head domain DUF2423 PF10338.4 EIE89890.1 - 2.9e-11 43.1 8.5 2.9e-11 43.1 5.9 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) PAP2_C PF14360.1 EIE89891.1 - 5.4e-17 61.8 9.5 5.4e-17 61.8 6.6 2.1 2 1 0 2 2 2 1 PAP2 superfamily C-terminal PAP2 PF01569.16 EIE89891.1 - 4.8e-06 26.2 4.8 4.8e-06 26.2 3.4 1.8 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 EIE89891.1 - 0.031 13.7 6.4 0.019 14.4 2.6 1.9 1 1 1 2 2 2 0 PAP2 superfamily DUF872 PF05915.7 EIE89891.1 - 0.15 11.9 1.0 0.41 10.5 0.0 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) HMG_box PF00505.14 EIE89892.1 - 1.7e-36 124.3 18.1 6.4e-19 67.9 1.1 2.9 3 0 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.5 EIE89892.1 - 7.7e-32 109.4 10.8 4.4e-16 59.0 1.3 2.8 2 1 1 3 3 3 2 HMG-box domain HMG_box_5 PF14887.1 EIE89892.1 - 0.025 14.3 2.1 0.025 14.3 1.5 2.7 1 1 2 3 3 3 0 HMG (high mobility group) box 5 Pkinase PF00069.20 EIE89893.1 - 1.5e-30 106.2 0.1 1.1e-23 83.7 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIE89893.1 - 2.7e-10 39.7 0.0 4.1e-05 22.7 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EIE89893.1 - 0.0066 16.2 0.1 0.082 12.6 0.0 2.3 2 1 1 3 3 3 1 Phosphotransferase enzyme family Peptidase_M20 PF01546.23 EIE89894.1 - 6.9e-31 107.2 0.0 1e-30 106.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EIE89894.1 - 1.3e-12 47.4 0.0 2.6e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain WG_beta_rep PF14903.1 EIE89894.1 - 0.08 13.2 0.0 0.22 11.8 0.0 1.7 1 0 0 1 1 1 0 WG containing repeat Mito_carr PF00153.22 EIE89895.1 - 7.3e-58 192.2 0.0 1.1e-22 79.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein CompInhib_SCIN PF11546.3 EIE89896.1 - 0.61 9.9 3.4 1.1 9.1 0.3 2.2 2 0 0 2 2 2 0 Staphylococcal complement inhibitor SCIN RNase_PH PF01138.16 EIE89897.1 - 1.4e-30 106.3 0.1 1.5e-30 106.1 0.0 1.0 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Rax2 PF12768.2 EIE89898.1 - 5.7e-49 166.8 25.6 2e-46 158.4 0.3 4.9 4 1 2 6 6 6 3 Cortical protein marker for cell polarity SH3_1 PF00018.23 EIE89898.1 - 8.2e-09 34.7 0.2 2.3e-08 33.2 0.1 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EIE89898.1 - 5e-06 26.0 0.1 1.2e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EIE89898.1 - 9.6e-05 21.7 0.0 0.00024 20.5 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain Pkinase PF00069.20 EIE89899.1 - 1.3e-61 207.9 0.0 1.7e-61 207.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE89899.1 - 2.1e-31 108.9 0.1 8e-31 107.0 0.1 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE89899.1 - 1.4e-05 24.1 0.0 2.5e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EIE89899.1 - 0.042 13.5 0.4 0.7 9.5 0.0 2.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family Imm46 PF15585.1 EIE89899.1 - 0.095 12.7 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 46 Pkinase PF00069.20 EIE89900.1 - 4.3e-12 45.7 0.0 1.2e-11 44.3 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE89900.1 - 1.9e-09 36.9 0.0 4.7e-09 35.7 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Nucleoplasmin PF03066.10 EIE89901.1 - 0.0002 20.9 7.1 0.0003 20.3 4.9 1.4 1 0 0 1 1 1 1 Nucleoplasmin Nop14 PF04147.7 EIE89901.1 - 0.0011 17.0 7.1 0.0013 16.7 4.9 1.1 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.7 EIE89901.1 - 0.0052 16.1 5.4 0.0065 15.7 3.7 1.2 1 0 0 1 1 1 1 SDA1 YL1 PF05764.8 EIE89901.1 - 0.0055 16.3 4.4 0.0055 16.3 3.0 1.9 2 0 0 2 2 2 1 YL1 nuclear protein TFIIF_alpha PF05793.7 EIE89901.1 - 0.0092 14.3 6.6 0.012 14.0 4.5 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) TRAP_alpha PF03896.11 EIE89901.1 - 0.01 14.8 3.0 0.01 14.8 2.0 1.9 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit CDC45 PF02724.9 EIE89901.1 - 0.024 12.7 5.3 0.028 12.4 3.6 1.1 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.5 EIE89901.1 - 0.029 13.4 11.2 0.038 13.0 7.8 1.2 1 0 0 1 1 1 0 BUD22 FAM176 PF14851.1 EIE89901.1 - 0.19 11.4 5.8 0.43 10.2 4.0 1.6 1 0 0 1 1 1 0 FAM176 family Sporozoite_P67 PF05642.6 EIE89901.1 - 0.21 9.3 6.7 0.3 8.9 4.6 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RXT2_N PF08595.6 EIE89901.1 - 1.1 9.0 13.1 0.95 9.2 7.4 2.0 2 0 0 2 2 2 0 RXT2-like, N-terminal DUF1510 PF07423.6 EIE89901.1 - 1.1 8.5 8.2 1.9 7.7 5.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) COPI_C PF06957.6 EIE89901.1 - 1.1 7.6 3.2 1.5 7.2 2.2 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Sigma70_ner PF04546.8 EIE89901.1 - 1.8 8.1 13.4 3.1 7.3 9.3 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF3306 PF11748.3 EIE89901.1 - 2.2 8.9 12.1 1.9 9.1 3.2 2.6 3 0 0 3 3 2 0 Protein of unknown function (DUF3306) PP_M1 PF03012.9 EIE89901.1 - 2.3 7.5 6.8 4.8 6.4 4.7 1.5 1 0 0 1 1 1 0 Phosphoprotein RRN3 PF05327.6 EIE89901.1 - 4.3 5.3 7.2 7 4.6 5.0 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CobT PF06213.7 EIE89901.1 - 6.9 5.7 15.2 11 5.0 10.6 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Gly_transf_sug PF04488.10 EIE89902.1 - 1.5e-06 28.5 0.4 3.1e-06 27.4 0.1 1.7 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 EIE89902.1 - 0.05 12.7 1.1 0.21 10.6 0.2 2.0 2 0 0 2 2 2 0 Capsular polysaccharide synthesis protein NIPSNAP PF07978.8 EIE89902.1 - 0.1 12.5 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 NIPSNAP DUF3584 PF12128.3 EIE89903.1 - 0.0058 14.0 2.2 0.006 14.0 1.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Sugarporin_N PF11471.3 EIE89903.1 - 0.014 15.0 0.3 0.029 13.9 0.2 1.5 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension DUF4351 PF14261.1 EIE89903.1 - 0.17 11.7 1.3 0.36 10.7 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4351) IncA PF04156.9 EIE89903.1 - 0.27 10.8 5.2 0.34 10.4 3.6 1.1 1 0 0 1 1 1 0 IncA protein Flavokinase PF01687.12 EIE89904.1 - 3.1e-39 133.7 0.0 3.6e-39 133.4 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase ATP_bind_1 PF03029.12 EIE89905.1 - 2.2e-81 272.8 0.1 2.6e-81 272.6 0.1 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_33 PF13671.1 EIE89905.1 - 0.0034 17.2 0.0 0.0065 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 EIE89905.1 - 0.0039 16.9 0.0 0.013 15.2 0.0 1.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B ArgK PF03308.11 EIE89905.1 - 0.0045 15.7 0.0 0.0083 14.9 0.0 1.3 1 0 0 1 1 1 1 ArgK protein AAA_17 PF13207.1 EIE89905.1 - 0.0048 17.7 1.7 0.017 15.9 1.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EIE89905.1 - 0.017 14.5 0.0 0.025 13.9 0.0 1.7 1 1 0 1 1 1 0 AAA-like domain MMR_HSR1 PF01926.18 EIE89905.1 - 0.02 14.8 1.0 0.19 11.6 0.4 2.5 1 1 1 2 2 2 0 50S ribosome-binding GTPase AAA_19 PF13245.1 EIE89905.1 - 0.022 14.4 0.1 0.048 13.4 0.1 1.5 1 0 0 1 1 1 0 Part of AAA domain cobW PF02492.14 EIE89905.1 - 0.043 13.2 0.0 0.67 9.3 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.1 EIE89905.1 - 0.059 12.9 0.0 0.099 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain CbiA PF01656.18 EIE89905.1 - 0.075 12.4 0.0 0.14 11.5 0.0 1.7 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain SRP54 PF00448.17 EIE89905.1 - 0.1 11.9 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_30 PF13604.1 EIE89905.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EIE89905.1 - 0.13 12.5 0.0 0.33 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.5 EIE89905.1 - 0.13 11.3 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA PF00004.24 EIE89905.1 - 0.14 12.3 0.0 0.4 10.8 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 EIE89905.1 - 0.16 11.6 0.0 0.45 10.2 0.0 1.7 2 0 0 2 2 2 0 NTPase CarboxypepD_reg PF13620.1 EIE89905.1 - 0.17 11.9 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain Zeta_toxin PF06414.7 EIE89905.1 - 0.18 10.8 0.0 0.38 9.8 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin F-box-like PF12937.2 EIE89906.1 - 1.3e-09 37.6 1.2 1.3e-09 37.6 0.8 2.3 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 EIE89906.1 - 9.1e-08 31.5 2.6 3.5e-07 29.6 0.6 3.0 2 0 0 2 2 2 1 F-box domain TPR_19 PF14559.1 EIE89906.1 - 6.8e-05 23.1 0.8 0.017 15.4 0.0 2.8 1 1 2 3 3 3 2 Tetratricopeptide repeat LRR_4 PF12799.2 EIE89906.1 - 0.0027 17.2 4.1 0.8 9.3 1.1 4.0 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) TPR_2 PF07719.12 EIE89906.1 - 0.017 14.9 0.0 1.7 8.7 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 EIE89906.1 - 0.04 13.5 0.3 0.1 12.2 0.2 1.7 1 0 0 1 1 1 0 TPR repeat Apc3 PF12895.2 EIE89906.1 - 2 8.5 9.0 0.66 10.1 2.2 2.7 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 DFP PF04127.10 EIE89907.1 - 2.2e-12 46.9 0.0 2.8e-05 23.8 0.0 2.7 2 1 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein BSP PF04450.7 EIE89907.1 - 0.078 12.4 0.1 0.32 10.4 0.0 1.9 2 0 0 2 2 2 0 Peptidase of plants and bacteria DDE_3 PF13358.1 EIE89909.1 - 8.8e-11 41.7 0.0 1.1e-10 41.3 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE89910.1 - 4.1e-09 36.3 0.2 1.5e-08 34.5 0.1 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.1 EIE89910.1 - 1.2e-06 28.3 0.0 1.6e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease GHMP_kinases_C PF08544.8 EIE89910.1 - 0.11 12.7 0.0 5.1 7.3 0.0 2.3 2 0 0 2 2 2 0 GHMP kinases C terminal TC1 PF15063.1 EIE89910.1 - 0.11 12.0 0.1 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Thyroid cancer protein 1 RVT_1 PF00078.22 EIE89911.1 - 8.5e-29 100.4 0.0 1.4e-28 99.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_Tnp_IS1595 PF12762.2 EIE89912.1 - 2.7e-06 27.3 0.1 4.8e-06 26.4 0.1 1.4 1 0 0 1 1 1 1 ISXO2-like transposase domain Exo_endo_phos_2 PF14529.1 EIE89913.1 - 4.3e-16 58.5 0.0 1.3e-15 57.0 0.0 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EIE89913.1 - 3.3e-06 27.2 0.1 8.9e-06 25.8 0.1 1.7 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family TSC22 PF01166.13 EIE89913.1 - 0.00013 21.8 0.6 0.00027 20.8 0.4 1.4 1 0 0 1 1 1 1 TSC-22/dip/bun family DUF972 PF06156.8 EIE89913.1 - 0.00015 22.0 1.6 0.00026 21.3 1.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF972) DUF904 PF06005.7 EIE89913.1 - 0.077 13.3 0.7 0.17 12.1 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF904) Mto2_bdg PF12808.2 EIE89914.1 - 0.35 11.0 6.3 4.6 7.4 0.2 3.3 3 0 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Transposase_21 PF02992.9 EIE89915.1 - 1.2e-22 80.0 0.1 1.2e-22 80.0 0.0 1.8 2 0 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.1 EIE89915.1 - 3.7e-05 23.1 0.5 8.4e-05 22.0 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) SDA1 PF05285.7 EIE89915.1 - 0.59 9.3 6.1 1.1 8.5 4.2 1.3 1 0 0 1 1 1 0 SDA1 HTH_Tnp_4 PF13613.1 EIE89916.1 - 0.0001 21.7 0.0 0.00017 21.0 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease HTH_23 PF13384.1 EIE89916.1 - 0.00057 19.4 0.1 0.0011 18.5 0.0 1.6 2 0 0 2 2 2 1 Homeodomain-like domain HTH_30 PF13556.1 EIE89916.1 - 0.04 13.5 0.0 0.095 12.3 0.0 1.6 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain RecX PF02631.11 EIE89916.1 - 0.096 12.9 0.1 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 RecX family RVT_1 PF00078.22 EIE89918.1 - 3.8e-27 95.0 0.2 7.4e-27 94.1 0.2 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Golgin_A5 PF09787.4 EIE89921.1 - 0.12 10.8 2.0 0.18 10.2 1.4 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 zf-CCHC PF00098.18 EIE89924.1 - 0.00045 20.0 12.6 0.028 14.3 0.3 2.9 3 0 0 3 3 3 2 Zinc knuckle zf-CCHC_4 PF14392.1 EIE89924.1 - 0.0017 18.0 2.9 0.065 12.9 0.4 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-nanos PF05741.8 EIE89924.1 - 1.4 8.9 4.8 6.2 6.8 3.3 2.0 1 1 0 1 1 1 0 Nanos RNA binding domain DDE_Tnp_IS1595 PF12762.2 EIE89925.1 - 3.5e-23 82.0 0.7 4.5e-23 81.7 0.5 1.1 1 0 0 1 1 1 1 ISXO2-like transposase domain DDE_Tnp_IS66 PF03050.9 EIE89925.1 - 0.016 14.4 0.1 0.022 14.0 0.1 1.1 1 0 0 1 1 1 0 Transposase IS66 family Adeno_terminal PF02459.10 EIE89926.1 - 0.19 9.8 1.3 0.25 9.4 0.9 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein Colipase PF01114.13 EIE89926.1 - 1 8.9 5.3 2.2 7.8 3.7 1.5 1 0 0 1 1 1 0 Colipase, N-terminal domain Ribosomal_L14 PF00238.14 EIE89928.1 - 8.3e-44 148.2 0.9 9.2e-44 148.1 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e ACP_syn_III PF08545.5 EIE89928.1 - 0.069 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III CoaE PF01121.15 EIE89929.1 - 7.2e-60 201.4 0.1 8.7e-60 201.1 0.1 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_17 PF13207.1 EIE89929.1 - 5.5e-05 23.9 0.1 0.00017 22.4 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EIE89929.1 - 0.0036 17.2 0.0 0.0083 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EIE89929.1 - 0.0058 16.9 0.5 0.028 14.7 0.4 2.1 1 1 0 1 1 1 1 AAA domain FOP_dimer PF09398.5 EIE89929.1 - 0.022 14.7 0.0 0.091 12.7 0.0 1.9 2 0 0 2 2 2 0 FOP N terminal dimerisation domain Med18 PF09637.5 EIE89929.1 - 0.035 13.6 0.0 0.054 13.0 0.0 1.3 1 0 0 1 1 1 0 Med18 protein DUF348 PF03990.9 EIE89929.1 - 0.077 12.5 0.1 0.41 10.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF348) AAA_33 PF13671.1 EIE89929.1 - 0.1 12.4 0.0 0.74 9.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 EIE89929.1 - 0.11 12.3 0.1 0.29 10.9 0.0 1.7 2 0 0 2 2 2 0 Dynamin family MCPVI PF02993.9 EIE89930.1 - 3.6 7.6 5.9 4.1 7.4 4.1 1.1 1 0 0 1 1 1 0 Minor capsid protein VI Ufd2P_core PF10408.4 EIE89931.1 - 1.3e-206 687.7 13.9 1.5e-206 687.5 9.6 1.0 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 EIE89931.1 - 2.7e-18 65.6 0.4 1e-17 63.8 0.3 2.1 1 0 0 1 1 1 1 U-box domain DRY_EERY PF09750.4 EIE89931.1 - 0.09 12.8 1.3 4.3 7.4 0.6 2.8 2 0 0 2 2 2 0 Alternative splicing regulator zf-C4H2 PF10146.4 EIE89931.1 - 0.17 11.8 3.1 0.14 12.1 0.7 1.9 2 0 0 2 2 2 0 Zinc finger-containing protein RNase_PH PF01138.16 EIE89932.1 - 2.3e-23 82.9 0.0 3.3e-23 82.4 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Pro_isomerase PF00160.16 EIE89933.1 - 1e-38 133.0 0.0 1.2e-38 132.7 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4576 PF15144.1 EIE89934.1 - 0.026 14.1 0.2 0.28 10.8 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4576) DPBB_1 PF03330.13 EIE89936.1 - 9.5e-07 28.7 0.1 1.9e-06 27.7 0.1 1.5 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EIE89936.1 - 0.0095 15.6 0.1 0.015 15.0 0.1 1.3 1 0 0 1 1 1 1 Barwin family DUF3039 PF11238.3 EIE89936.1 - 0.14 11.6 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3039) Pro_dh PF01619.13 EIE89937.1 - 9.1e-59 198.9 1.4 1.5e-58 198.2 1.0 1.3 1 0 0 1 1 1 1 Proline dehydrogenase zf-met PF12874.2 EIE89938.1 - 3.4e-07 30.2 1.8 3.4e-07 30.2 1.2 1.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.4 EIE89938.1 - 0.00011 21.7 0.9 0.00018 21.1 0.6 1.3 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein PRP4 PF08799.6 EIE89938.1 - 0.035 13.3 0.6 0.061 12.6 0.4 1.4 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like CBS PF00571.23 EIE89939.1 - 1.6e-37 127.0 5.4 3.5e-09 36.3 0.0 5.2 5 1 0 5 5 5 4 CBS domain PB1 PF00564.19 EIE89939.1 - 1.6e-10 40.4 0.8 2.9e-10 39.6 0.1 1.8 2 0 0 2 2 2 1 PB1 domain P22_AR_C PF10548.4 EIE89939.1 - 0.12 12.2 0.1 0.35 10.7 0.1 1.8 1 0 0 1 1 1 0 P22AR C-terminal domain RNA_pol_Rpc82 PF05645.8 EIE89939.1 - 0.26 10.7 7.8 0.16 11.4 1.5 2.9 2 1 0 2 2 2 0 RNA polymerase III subunit RPC82 LRR_8 PF13855.1 EIE89941.1 - 6e-17 61.1 25.1 2e-09 37.0 5.7 3.5 3 1 1 4 4 4 3 Leucine rich repeat LRR_4 PF12799.2 EIE89941.1 - 2.4e-13 49.3 17.2 2.7e-06 26.8 0.2 3.9 2 1 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EIE89941.1 - 8.9e-13 46.3 15.4 0.003 17.3 0.3 6.3 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_7 PF13504.1 EIE89941.1 - 5.6e-09 34.7 17.1 0.013 15.5 0.2 5.8 6 0 0 6 6 6 3 Leucine rich repeat LRR_6 PF13516.1 EIE89941.1 - 4.7e-07 29.2 12.3 0.087 12.9 0.1 4.5 3 1 1 4 4 4 3 Leucine Rich repeat LRR_9 PF14580.1 EIE89941.1 - 0.042 13.4 0.5 0.18 11.3 0.2 1.9 1 1 1 2 2 2 0 Leucine-rich repeat LRR_5 PF13306.1 EIE89941.1 - 0.042 13.5 0.1 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 Leucine rich repeats (6 copies) DUF2076 PF09849.4 EIE89942.1 - 0.11 12.5 2.0 0.14 12.1 1.4 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) SPX PF03105.14 EIE89942.1 - 0.16 11.7 5.0 0.21 11.3 3.4 1.3 1 0 0 1 1 1 0 SPX domain SlyX PF04102.7 EIE89942.1 - 5.4 7.4 8.5 0.26 11.6 1.5 2.1 3 0 0 3 3 3 0 SlyX PTR2 PF00854.16 EIE89943.1 - 4.5e-18 65.1 1.7 5.5e-18 64.8 1.2 1.1 1 0 0 1 1 1 1 POT family MFS_1 PF07690.11 EIE89943.1 - 0.0072 15.0 2.7 0.021 13.5 2.2 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Ocular_alb PF02101.10 EIE89943.1 - 0.035 12.7 1.2 0.046 12.3 0.8 1.2 1 0 0 1 1 1 0 Ocular albinism type 1 protein DUF4018 PF13210.1 EIE89943.1 - 0.18 11.2 1.6 1.1 8.5 0.3 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4018) Acyl_transf_3 PF01757.17 EIE89943.1 - 0.18 10.5 4.1 0.22 10.3 2.9 1.1 1 0 0 1 1 1 0 Acyltransferase family Copper-fist PF00649.13 EIE89945.1 - 2.5e-17 61.7 2.7 7.5e-17 60.2 1.9 1.8 1 0 0 1 1 1 1 Copper fist DNA binding domain ATP-synt_C PF00137.16 EIE89946.1 - 0.38 10.6 5.2 1.6 8.6 0.3 2.6 1 1 2 3 3 3 0 ATP synthase subunit C Erf4 PF10256.4 EIE89947.1 - 1.2e-13 50.9 0.0 1.4e-13 50.7 0.0 1.0 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Glyco_hydro_18 PF00704.23 EIE89948.1 - 1.8e-64 218.3 5.4 7.4e-62 209.7 3.7 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 ubiquitin PF00240.18 EIE89949.1 - 5e-35 118.7 1.3 6.5e-35 118.3 0.9 1.1 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.12 EIE89949.1 - 9.8e-31 105.1 11.1 1.6e-30 104.4 7.7 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.3 EIE89949.1 - 2.5e-20 71.9 1.0 4e-20 71.2 0.7 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EIE89949.1 - 2.9e-06 27.4 0.2 1e-05 25.6 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EIE89949.1 - 0.00011 21.9 0.0 0.00016 21.4 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EIE89949.1 - 0.003 17.4 0.1 0.0058 16.4 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EIE89949.1 - 0.0045 17.1 0.1 0.0046 17.1 0.0 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 EIE89949.1 - 0.091 12.8 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2870) Plexin_cytopl PF08337.7 EIE89949.1 - 0.16 10.2 0.7 2.8 6.1 0.3 2.0 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain Fer2_3 PF13085.1 EIE89949.1 - 0.22 11.3 2.0 0.92 9.3 0.9 2.1 1 1 1 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain Polysacc_synt_4 PF04669.8 EIE89950.1 - 5.1e-23 81.4 1.5 1.9e-21 76.3 1.1 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis HLH PF00010.21 EIE89951.1 - 2.7e-15 55.8 0.2 2.7e-15 55.8 0.1 2.2 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain GATA PF00320.22 EIE89952.1 - 3e-32 109.6 17.2 2.2e-16 58.8 1.9 2.4 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 EIE89952.1 - 9.3e-05 21.6 8.1 0.009 15.3 0.7 2.6 2 0 0 2 2 2 2 TFIIB zinc-binding ArfGap PF01412.13 EIE89952.1 - 0.00029 20.5 1.9 0.53 10.0 0.1 2.4 2 0 0 2 2 2 2 Putative GTPase activating protein for Arf Zn-ribbon_8 PF09723.5 EIE89952.1 - 0.03 14.2 6.2 0.79 9.7 0.2 2.9 3 0 0 3 3 3 0 Zinc ribbon domain NMD3 PF04981.8 EIE89952.1 - 0.042 12.9 2.6 0.62 9.1 0.1 2.3 2 0 0 2 2 2 0 NMD3 family COX5B PF01215.14 EIE89952.1 - 0.14 11.8 3.1 1.2 8.7 0.1 2.8 2 1 0 2 2 2 0 Cytochrome c oxidase subunit Vb RRN7 PF11781.3 EIE89952.1 - 0.18 11.3 5.4 2.2 7.8 0.4 2.5 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 eIF-5_eIF-2B PF01873.12 EIE89952.1 - 0.53 9.9 5.3 5.8 6.5 0.3 2.5 2 0 0 2 2 2 0 Domain found in IF2B/IF5 DZR PF12773.2 EIE89952.1 - 1.1 9.1 14.5 0.95 9.3 1.1 3.3 2 1 2 4 4 4 0 Double zinc ribbon FYVE PF01363.16 EIE89952.1 - 2.1 8.3 8.0 2.8 7.9 2.4 2.9 2 1 0 2 2 2 0 FYVE zinc finger Prim_Zn_Ribbon PF08273.7 EIE89952.1 - 2.3 8.3 7.4 6.4 6.9 0.4 2.6 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase Ras PF00071.17 EIE89953.1 - 3.8e-52 175.9 0.1 4.7e-52 175.6 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIE89953.1 - 7.4e-18 65.1 0.0 1.4e-17 64.2 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIE89953.1 - 1.3e-13 50.5 0.3 1.7e-13 50.1 0.2 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EIE89953.1 - 2.5e-05 23.5 0.1 2.8e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EIE89953.1 - 0.00079 19.3 0.0 0.0018 18.2 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EIE89953.1 - 0.0012 18.3 0.2 0.0023 17.3 0.1 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EIE89953.1 - 0.032 13.4 0.0 0.054 12.6 0.0 1.6 2 1 0 2 2 2 0 Protein of unknown function, DUF258 SRPRB PF09439.5 EIE89953.1 - 0.053 12.7 0.0 0.072 12.3 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PNPase PF03726.9 EIE89953.1 - 0.083 13.1 0.2 0.17 12.1 0.1 1.5 1 0 0 1 1 1 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain zf-C2H2 PF00096.21 EIE89954.1 - 6e-15 54.5 16.6 0.00012 22.1 0.7 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIE89954.1 - 5.6e-14 51.6 14.4 1.3e-06 28.4 0.4 3.9 4 0 0 4 4 4 2 Zinc-finger double domain Myb_DNA-binding PF00249.26 EIE89954.1 - 3.5e-13 49.3 0.8 1.3e-12 47.5 0.3 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EIE89954.1 - 3.8e-11 42.9 2.9 6.5e-11 42.1 0.8 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain zf-C2H2_4 PF13894.1 EIE89954.1 - 2.5e-10 39.9 13.4 0.0075 16.5 0.5 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EIE89954.1 - 0.00041 20.1 8.5 0.016 15.0 0.7 3.4 3 0 0 3 3 3 1 C2H2-type zinc finger Zn_Tnp_IS1595 PF12760.2 EIE89954.1 - 0.01 15.6 8.1 0.029 14.1 3.2 3.0 2 1 1 3 3 3 0 Transposase zinc-ribbon domain DUF4054 PF13262.1 EIE89954.1 - 0.013 15.6 5.5 1.6 8.9 0.3 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4054) Phage_connect_1 PF05135.8 EIE89954.1 - 0.015 15.4 1.5 0.11 12.7 0.5 2.4 2 0 0 2 2 2 0 Phage gp6-like head-tail connector protein zf-C2H2_jaz PF12171.3 EIE89954.1 - 0.048 13.8 6.3 2.2 8.5 0.1 3.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.5 EIE89954.1 - 0.23 11.4 6.6 5.5 7.0 0.8 3.0 1 1 0 2 2 2 0 Zinc ribbon domain GAGA PF09237.6 EIE89954.1 - 0.37 10.4 3.2 0.5 9.9 0.3 2.7 2 1 0 2 2 2 0 GAGA factor zf-met PF12874.2 EIE89954.1 - 0.41 10.9 11.9 3.7 7.8 0.2 3.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Zn_Tnp_IS1 PF03811.8 EIE89954.1 - 3.1 7.3 6.6 3.6 7.1 3.2 2.2 2 0 0 2 2 2 0 InsA N-terminal domain Rap1_C PF11626.3 EIE89954.1 - 3.4 7.6 5.4 62 3.5 3.7 2.5 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain C1_4 PF07975.7 EIE89954.1 - 4.6 7.3 7.0 2.9 7.9 2.2 2.4 1 1 0 1 1 1 0 TFIIH C1-like domain Cullin PF00888.17 EIE89955.1 - 4.6e-163 543.9 23.9 5.6e-163 543.6 16.6 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EIE89955.1 - 1.8e-29 101.3 8.0 2.6e-29 100.8 2.7 3.3 4 0 0 4 4 4 1 Cullin protein neddylation domain HTH_34 PF13601.1 EIE89955.1 - 0.04 13.9 0.1 0.15 12.1 0.1 2.0 1 0 0 1 1 1 0 Winged helix DNA-binding domain DUF4404 PF14357.1 EIE89955.1 - 0.39 11.1 6.7 1.2 9.6 0.1 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4404) DUF1053 PF06327.9 EIE89955.1 - 1.3 9.4 7.4 11 6.4 0.3 3.7 2 1 1 3 3 3 0 Domain of Unknown Function (DUF1053) Tmemb_14 PF03647.8 EIE89956.1 - 6.4e-26 90.5 3.0 7.6e-26 90.3 2.1 1.1 1 0 0 1 1 1 1 Transmembrane proteins 14C Gly-zipper_OmpA PF13436.1 EIE89956.1 - 4.3 7.0 6.0 6.4 6.4 4.1 1.3 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Gly-zipper_YMGG PF13441.1 EIE89956.1 - 4.9 6.7 10.4 1.5 8.4 3.0 2.3 2 0 0 2 2 2 0 YMGG-like Gly-zipper TPR_11 PF13414.1 EIE89957.1 - 7.7e-24 83.1 9.4 1.8e-08 33.9 0.1 6.2 5 0 0 5 5 5 4 TPR repeat TPR_16 PF13432.1 EIE89957.1 - 4.3e-19 68.6 3.4 7.2e-05 23.3 0.0 5.0 3 1 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 EIE89957.1 - 1.7e-18 64.9 12.3 0.018 14.9 0.1 10.4 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_1 PF00515.23 EIE89957.1 - 8.6e-15 53.6 18.0 0.0064 16.0 0.2 8.5 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_14 PF13428.1 EIE89957.1 - 1.2e-13 50.3 4.1 0.094 13.3 0.0 7.2 5 2 2 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.1 EIE89957.1 - 1.9e-13 49.1 9.3 0.11 12.3 0.3 8.4 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.1 EIE89957.1 - 1.9e-10 40.9 6.3 0.19 12.0 0.0 6.3 5 2 1 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.1 EIE89957.1 - 2.3e-10 40.2 18.5 0.0027 17.6 0.4 7.3 6 2 2 8 8 8 4 Tetratricopeptide repeat TPR_7 PF13176.1 EIE89957.1 - 1.6e-09 36.8 4.1 0.00023 20.7 0.1 6.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.1 EIE89957.1 - 1.7e-09 37.5 7.3 0.79 10.3 0.1 8.1 9 0 0 9 9 7 2 Tetratricopeptide repeat TPR_17 PF13431.1 EIE89957.1 - 2.1e-08 33.7 6.8 0.71 10.2 0.0 7.4 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_9 PF13371.1 EIE89957.1 - 8.4e-05 22.3 1.2 0.009 15.8 0.0 3.9 3 2 2 5 5 5 1 Tetratricopeptide repeat TPR_20 PF14561.1 EIE89957.1 - 0.0027 17.8 6.7 0.052 13.6 0.0 5.1 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.1 EIE89957.1 - 0.0039 17.0 12.2 0.52 10.3 0.0 6.9 8 0 0 8 8 8 1 Tetratricopeptide repeat Apc3 PF12895.2 EIE89957.1 - 0.0052 16.9 12.6 1.4 9.1 0.1 5.5 5 2 0 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 RRM_1 PF00076.17 EIE89960.1 - 1.9e-06 27.4 0.1 7.5e-06 25.4 0.0 1.9 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE89960.1 - 0.00076 19.4 0.0 0.0016 18.3 0.0 1.6 1 1 1 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE89960.1 - 0.0022 17.8 0.8 0.0033 17.2 0.1 1.7 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TEA PF01285.13 EIE89961.1 - 2.2e-34 119.3 8.7 2.3e-32 112.7 0.9 2.8 2 1 0 2 2 2 2 TEA/ATTS domain family His_kinase PF06580.8 EIE89961.1 - 0.049 13.5 3.6 0.28 11.1 0.0 2.8 1 1 1 2 2 2 0 Histidine kinase MFS_1 PF07690.11 EIE89962.1 - 1.7e-35 122.4 27.1 2.3e-35 121.9 18.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily PX PF00787.19 EIE89963.1 - 1.3e-21 76.4 1.1 2.6e-21 75.5 0.1 2.0 3 0 0 3 3 3 1 PX domain Vps5 PF09325.5 EIE89963.1 - 5.2e-12 45.5 6.9 1.5e-06 27.6 0.4 2.5 3 0 0 3 3 3 2 Vps5 C terminal like BAR_3_WASP_bdg PF10456.4 EIE89963.1 - 0.0035 16.6 2.4 0.03 13.5 0.2 2.5 2 1 0 2 2 2 1 WASP-binding domain of Sorting nexin protein BAR PF03114.13 EIE89963.1 - 0.0084 15.6 2.5 0.37 10.2 0.0 2.3 2 0 0 2 2 2 2 BAR domain Peptidase_C10 PF01640.12 EIE89963.1 - 0.026 14.3 0.2 0.049 13.4 0.1 1.4 1 0 0 1 1 1 0 Peptidase C10 family DUF3510 PF12022.3 EIE89963.1 - 0.031 14.4 0.2 0.098 12.7 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3510) DUF2535 PF10751.4 EIE89963.1 - 0.11 12.6 0.8 1.8 8.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2535) DUF1451 PF07295.6 EIE89963.1 - 3.8 7.2 5.8 1.7 8.4 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1451) ThiF PF00899.16 EIE89964.1 - 1.1e-23 83.5 0.1 1.7e-23 82.9 0.1 1.2 1 0 0 1 1 1 1 ThiF family ELFV_dehydrog PF00208.16 EIE89964.1 - 0.00046 19.8 0.1 0.00068 19.2 0.1 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ApbA PF02558.11 EIE89964.1 - 0.0083 15.5 0.1 0.015 14.7 0.1 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.14 EIE89964.1 - 0.0093 15.0 0.0 0.012 14.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain TrkA_N PF02254.13 EIE89964.1 - 0.01 15.8 0.1 0.22 11.5 0.0 2.2 1 1 1 2 2 2 0 TrkA-N domain 3HCDH_N PF02737.13 EIE89964.1 - 0.043 13.4 0.2 0.081 12.5 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EIE89964.1 - 0.12 12.4 0.2 0.2 11.7 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase CS PF04969.11 EIE89965.1 - 1.1e-20 73.9 1.7 1.8e-20 73.2 1.2 1.4 1 0 0 1 1 1 1 CS domain HMG_box PF00505.14 EIE89966.1 - 0.00038 20.6 0.3 0.0033 17.6 0.0 2.5 1 1 1 2 2 2 1 HMG (high mobility group) box Glyco_hydro_15 PF00723.16 EIE89968.1 - 3e-38 131.5 0.0 3.9e-25 88.3 0.0 4.0 2 2 0 2 2 2 2 Glycosyl hydrolases family 15 Methyltransf_11 PF08241.7 EIE89969.1 - 2e-15 57.0 0.0 5e-14 52.5 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIE89969.1 - 9.3e-13 48.0 0.4 6.7e-12 45.2 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIE89969.1 - 1.5e-12 47.4 0.0 3.8e-12 46.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIE89969.1 - 9.7e-11 41.9 0.0 3.4e-10 40.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIE89969.1 - 1.4e-10 41.7 0.0 6.4e-10 39.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIE89969.1 - 1.7e-10 41.2 0.0 6.6e-10 39.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIE89969.1 - 3.5e-08 32.8 0.0 1.1e-07 31.2 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 EIE89969.1 - 6.2e-05 22.1 0.0 0.0012 17.9 0.0 2.5 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_8 PF05148.10 EIE89969.1 - 0.00019 21.1 0.0 0.00029 20.5 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase FtsJ PF01728.14 EIE89969.1 - 0.00027 21.0 0.0 0.00057 19.9 0.0 1.7 1 1 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.9 EIE89969.1 - 0.00091 18.6 0.0 0.0027 17.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain MetW PF07021.7 EIE89969.1 - 0.00093 18.6 0.0 0.0023 17.3 0.0 1.6 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_9 PF08003.6 EIE89969.1 - 0.0029 16.3 0.0 0.0052 15.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_2 PF00891.13 EIE89969.1 - 0.0044 16.2 0.0 0.01 15.0 0.0 1.7 1 1 0 1 1 1 1 O-methyltransferase CMAS PF02353.15 EIE89969.1 - 0.0068 15.5 0.0 0.014 14.4 0.0 1.6 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 EIE89969.1 - 0.013 15.5 0.0 0.026 14.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain BBS2_Mid PF14783.1 EIE89970.1 - 0.0021 17.8 0.1 1.5 8.6 0.0 2.6 2 0 0 2 2 2 2 Ciliary BBSome complex subunit 2, middle region FG-GAP PF01839.18 EIE89970.1 - 0.12 12.0 0.7 0.4 10.4 0.3 2.2 2 0 0 2 2 2 0 FG-GAP repeat NOA36 PF06524.7 EIE89970.1 - 9.4 5.3 16.9 24 4.0 11.7 1.6 1 0 0 1 1 1 0 NOA36 protein polyprenyl_synt PF00348.12 EIE89971.1 - 1.5e-76 256.6 0.0 1.8e-76 256.4 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Musclin PF11037.3 EIE89971.1 - 0.077 12.6 0.1 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Insulin-resistance promoting peptide in skeletal muscle TTKRSYEDQ PF10212.4 EIE89972.1 - 1.1e-06 27.8 23.5 1.1e-06 27.8 16.3 1.7 1 1 0 1 1 1 1 Predicted coiled-coil domain-containing protein Acylphosphatase PF00708.13 EIE89972.1 - 0.18 11.9 0.3 0.18 11.9 0.2 3.3 3 1 0 3 3 3 0 Acylphosphatase Methyltransf_1N PF02870.10 EIE89972.1 - 0.22 12.1 5.5 0.15 12.6 1.1 2.7 2 1 1 3 3 3 0 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain Methyltransf_12 PF08242.7 EIE89972.1 - 1.3 9.5 4.2 1.7 9.2 0.0 2.9 1 1 1 2 2 2 0 Methyltransferase domain XPG_I_2 PF12813.2 EIE89972.1 - 2.4 7.5 16.5 1.2 8.5 3.9 2.6 1 1 0 2 2 2 0 XPG domain containing COG2 PF06148.6 EIE89972.1 - 3.5 7.5 23.3 0.064 13.1 3.6 3.4 2 2 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Nop PF01798.13 EIE89973.1 - 4.2e-44 149.4 0.2 1.3e-43 147.9 0.1 1.9 1 0 0 1 1 1 1 Putative snoRNA binding domain Prp31_C PF09785.4 EIE89973.1 - 1.2e-37 129.0 1.3 1.2e-37 129.0 0.9 2.3 2 0 0 2 2 2 1 Prp31 C terminal domain NOSIC PF08060.8 EIE89973.1 - 2.6e-21 75.1 0.1 7.1e-21 73.7 0.1 1.8 1 0 0 1 1 1 1 NOSIC (NUC001) domain ABC2_membrane_3 PF12698.2 EIE89973.1 - 2 7.3 3.1 3.5 6.5 2.1 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein Pyr_redox PF00070.22 EIE89974.1 - 4.9e-12 46.0 0.0 1.9e-11 44.2 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EIE89974.1 - 6.5e-12 45.7 0.0 1.9e-10 40.9 0.0 3.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EIE89974.1 - 0.00067 18.6 0.0 0.0051 15.7 0.0 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EIE89974.1 - 0.0007 19.7 0.0 0.0064 16.5 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EIE89974.1 - 0.002 17.9 0.0 1.2 8.8 0.0 3.3 2 1 1 3 3 3 1 FAD-NAD(P)-binding RGS PF00615.14 EIE89974.1 - 0.0021 18.1 0.2 0.0035 17.4 0.1 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain K_oxygenase PF13434.1 EIE89974.1 - 0.004 16.1 0.0 0.012 14.5 0.0 1.7 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EIE89974.1 - 0.017 15.1 0.0 0.059 13.3 0.0 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain MannoseP_isomer PF01050.13 EIE89974.1 - 0.024 14.2 0.1 0.049 13.2 0.0 1.4 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase FAD_binding_3 PF01494.14 EIE89974.1 - 0.063 12.3 0.0 0.096 11.7 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain TrkA_N PF02254.13 EIE89974.1 - 0.091 12.7 0.0 0.23 11.4 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain ThiF PF00899.16 EIE89974.1 - 0.098 12.4 0.0 0.27 11.0 0.0 1.7 2 0 0 2 2 2 0 ThiF family HEAT PF02985.17 EIE89975.1 - 3.7e-05 23.4 0.0 0.23 11.6 0.0 4.5 4 0 0 4 4 4 1 HEAT repeat Epimerase_2 PF02350.14 EIE89975.1 - 0.013 14.3 0.1 0.64 8.7 0.0 2.4 2 0 0 2 2 2 0 UDP-N-acetylglucosamine 2-epimerase HEAT_2 PF13646.1 EIE89975.1 - 0.02 15.1 0.1 3.2 8.0 0.0 3.8 3 1 1 4 4 4 0 HEAT repeats TPR_12 PF13424.1 EIE89976.1 - 1.1e-12 47.7 9.5 1.1e-05 25.2 0.4 3.8 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 EIE89976.1 - 1.2e-08 35.3 0.6 0.02 15.5 0.2 3.8 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EIE89976.1 - 1.9e-08 33.5 2.4 0.0026 17.2 0.1 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 EIE89976.1 - 2.7e-08 33.0 7.3 0.0011 18.6 0.2 3.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 EIE89976.1 - 4.3e-08 32.7 5.9 0.0049 16.4 0.2 3.7 1 1 0 3 3 3 2 TPR repeat TPR_7 PF13176.1 EIE89976.1 - 5.2e-08 32.1 5.1 0.0072 16.0 0.1 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EIE89976.1 - 5.2e-07 29.1 11.1 0.014 15.3 0.0 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 EIE89976.1 - 8.2e-07 29.1 4.6 2.2 9.1 0.1 5.2 4 1 1 5 5 5 2 Tetratricopeptide repeat SNAP PF14938.1 EIE89976.1 - 3e-06 26.6 1.3 0.015 14.4 0.1 2.5 1 1 1 2 2 2 2 Soluble NSF attachment protein, SNAP TPR_10 PF13374.1 EIE89976.1 - 9.5e-06 25.3 5.8 2.2 8.3 0.1 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 EIE89976.1 - 3.1e-05 24.2 5.1 0.12 12.6 0.1 4.0 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_21 PF09976.4 EIE89976.1 - 0.00035 20.5 4.2 0.043 13.7 0.1 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat RPN7 PF10602.4 EIE89976.1 - 0.0018 17.6 1.2 0.32 10.3 0.3 3.1 2 1 0 2 2 2 1 26S proteasome subunit RPN7 MIT PF04212.13 EIE89976.1 - 0.0028 17.5 4.0 0.7 9.8 0.3 4.1 3 1 1 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_17 PF13431.1 EIE89976.1 - 0.02 15.0 0.2 5.6 7.4 0.0 3.9 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 EIE89976.1 - 0.64 10.5 5.4 1.6 9.3 0.1 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat Chitin_synth_2 PF03142.10 EIE89977.1 - 4.7e-243 807.3 0.0 4.7e-243 807.3 0.0 1.5 2 0 0 2 2 2 1 Chitin synthase Myosin_head PF00063.16 EIE89977.1 - 9.9e-85 284.9 0.0 1.3e-84 284.6 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.23 EIE89977.1 - 2.7e-20 71.9 0.1 3.5e-14 52.3 0.0 2.8 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.6 EIE89977.1 - 1.1e-18 66.7 0.3 1.4e-17 63.2 0.2 2.6 2 0 0 2 2 2 1 DEK C terminal domain Glyco_trans_2_3 PF13632.1 EIE89977.1 - 1e-14 54.7 1.3 3.7e-14 52.8 0.9 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EIE89977.1 - 3.1e-14 53.3 0.0 7e-11 42.3 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EIE89977.1 - 1.9e-05 24.4 0.0 0.0016 18.1 0.0 2.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EIE89977.1 - 0.0034 16.6 0.0 0.0079 15.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 Utp14 PF04615.8 EIE89978.1 - 3.8e-163 544.4 101.8 6.6e-99 332.0 50.6 3.0 1 1 2 3 3 3 2 Utp14 protein DUF2999 PF11212.3 EIE89980.1 - 0.1 12.6 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2999) MFS_1 PF07690.11 EIE89981.1 - 3.2e-24 85.2 45.2 5.8e-24 84.4 31.3 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily zf-MYND PF01753.13 EIE89982.1 - 3.4e-08 33.2 15.3 7.2e-08 32.1 10.6 1.6 1 0 0 1 1 1 1 MYND finger Amino_oxidase PF01593.19 EIE89983.1 - 3.8e-64 217.4 0.0 5.9e-50 170.6 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EIE89983.1 - 1.4e-10 41.0 0.1 3.6e-10 39.7 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EIE89983.1 - 2.4e-06 26.6 0.2 0.0009 18.2 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EIE89983.1 - 7.3e-06 26.1 0.1 0.00015 21.8 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EIE89983.1 - 5.9e-05 23.3 1.0 0.013 15.9 0.2 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EIE89983.1 - 0.00021 20.2 0.3 0.00034 19.5 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 EIE89983.1 - 0.0012 17.9 0.3 0.0029 16.7 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 EIE89983.1 - 0.0014 17.2 2.5 0.26 9.6 0.3 2.9 3 0 0 3 3 3 2 HI0933-like protein FAD_oxidored PF12831.2 EIE89983.1 - 0.0059 15.7 0.0 0.019 14.0 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EIE89983.1 - 0.025 13.4 0.3 1.8 7.3 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.12 EIE89983.1 - 0.033 13.2 0.1 0.061 12.4 0.1 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.1 EIE89983.1 - 0.058 13.1 0.4 5.6 6.7 0.1 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EIE89983.1 - 0.063 13.1 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EIE89983.1 - 0.15 10.8 0.4 0.31 9.8 0.3 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A SNARE_assoc PF09335.6 EIE89984.1 - 7.6e-21 74.5 8.3 2.6e-20 72.8 4.6 2.2 2 1 0 2 2 2 1 SNARE associated Golgi protein Ebp2 PF05890.7 EIE89985.1 - 0.054 12.8 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic rRNA processing protein EBP2 Glyco_transf_15 PF01793.11 EIE89986.1 - 6.1e-132 439.5 14.1 7.6e-132 439.2 9.8 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase SelR PF01641.13 EIE89988.1 - 4.7e-54 181.3 0.1 5.3e-54 181.1 0.0 1.0 1 0 0 1 1 1 1 SelR domain DUF2296 PF10058.4 EIE89988.1 - 0.042 13.6 1.0 0.36 10.6 0.0 2.1 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) Endonuclease_7 PF02945.10 EIE89988.1 - 0.18 11.5 1.9 1.6 8.5 1.3 2.0 1 1 0 1 1 1 0 Recombination endonuclease VII Ribosomal_S10 PF00338.17 EIE89989.1 - 2.3e-31 107.4 0.6 2.7e-31 107.2 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Methyltransf_3 PF01596.12 EIE89990.1 - 7.8e-16 57.7 0.0 8.1e-16 57.6 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EIE89990.1 - 5.7e-05 23.6 0.0 6.2e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EIE89990.1 - 0.00031 20.3 0.0 0.00037 20.0 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CmcI PF04989.7 EIE89990.1 - 0.00089 18.6 0.0 0.00098 18.4 0.0 1.0 1 0 0 1 1 1 1 Cephalosporin hydroxylase Methyltransf_26 PF13659.1 EIE89990.1 - 0.014 15.4 0.0 0.016 15.2 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.4 EIE89990.1 - 0.025 14.0 0.0 0.029 13.8 0.0 1.0 1 0 0 1 1 1 0 Putative methyltransferase Rsm22 PF09243.5 EIE89990.1 - 0.031 13.3 0.0 0.034 13.1 0.0 1.0 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_24 PF13578.1 EIE89990.1 - 0.036 14.8 0.0 0.042 14.6 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EIE89990.1 - 0.052 12.9 0.0 0.061 12.6 0.0 1.0 1 0 0 1 1 1 0 Methyltransferase small domain rve PF00665.21 EIE89993.1 - 1.9e-22 79.6 0.0 4.5e-22 78.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE89993.1 - 1.4e-15 57.2 0.1 2.8e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.12 EIE89993.1 - 8e-09 35.4 0.1 2.3e-08 34.0 0.1 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein Chromo PF00385.19 EIE89993.1 - 4.2e-08 32.7 0.1 9.7e-08 31.5 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 EIE89993.1 - 0.00047 19.4 1.6 0.0015 17.9 1.1 1.9 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger UBN2 PF14223.1 EIE89993.1 - 0.12 12.1 0.0 0.36 10.6 0.0 1.8 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Chromo PF00385.19 EIE89994.1 - 3.5e-15 55.4 1.1 6.1e-15 54.6 0.7 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.21 EIE89995.1 - 7.5e-19 68.0 0.0 1.9e-18 66.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE89995.1 - 4.5e-17 62.1 0.8 9.1e-17 61.1 0.2 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 EIE89995.1 - 0.00038 20.9 0.0 0.00087 19.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 EIE89995.1 - 0.00045 20.0 0.1 0.0015 18.4 0.1 1.9 1 0 0 1 1 1 1 Retroviral aspartyl protease F_actin_bind PF08919.5 EIE89995.1 - 0.043 13.5 0.1 0.31 10.7 0.0 2.5 2 0 0 2 2 2 0 F-actin binding RNase_H PF00075.19 EIE89995.1 - 0.07 13.4 0.0 0.2 12.0 0.0 1.7 1 0 0 1 1 1 0 RNase H DDE_Tnp_IS1595 PF12762.2 EIE89996.1 - 4.5e-07 29.8 0.1 1.1e-06 28.5 0.1 1.6 1 0 0 1 1 1 1 ISXO2-like transposase domain Polysacc_deac_1 PF01522.16 EIE89997.1 - 0.017 14.7 0.1 1.9 8.1 0.0 2.1 2 0 0 2 2 2 0 Polysaccharide deacetylase Lzipper-MIP1 PF14389.1 EIE89998.1 - 0.0049 16.9 0.4 0.013 15.5 0.3 1.7 1 0 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 ChaB PF06150.7 EIE89998.1 - 0.069 12.9 0.6 0.25 11.1 0.1 2.2 2 0 0 2 2 2 0 ChaB IncA PF04156.9 EIE89998.1 - 0.17 11.5 1.2 0.28 10.7 0.9 1.4 1 0 0 1 1 1 0 IncA protein DUF4404 PF14357.1 EIE89998.1 - 0.21 11.9 1.9 5.7 7.4 0.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) SRR PF07709.6 EIE89998.1 - 0.23 11.7 4.4 5.5 7.6 0.0 3.5 3 0 0 3 3 3 0 Seven Residue Repeat Transposase_21 PF02992.9 EIE89999.1 - 2e-22 79.4 0.1 2e-22 79.4 0.1 1.6 2 0 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.1 EIE89999.1 - 3.8e-05 23.1 0.3 8.6e-05 21.9 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) DUF1759 PF03564.10 EIE90000.1 - 8.8e-05 22.3 0.6 0.00011 22.0 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) Retrotrans_gag PF03732.12 EIE90000.1 - 0.0089 16.0 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein DDE_3 PF13358.1 EIE90001.1 - 2.6e-07 30.4 0.0 6.4e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.1 EIE90001.1 - 0.00022 21.9 0.0 0.00051 20.7 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain CP12 PF02672.10 EIE90001.1 - 0.0023 18.3 1.1 0.0051 17.2 0.8 1.5 1 0 0 1 1 1 1 CP12 domain HTH_Tnp_1 PF01527.15 EIE90001.1 - 0.015 15.2 0.7 0.029 14.3 0.5 1.4 1 0 0 1 1 1 0 Transposase HTH_29 PF13551.1 EIE90001.1 - 0.075 13.1 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn helix FAM219A PF15260.1 EIE90001.1 - 0.077 13.3 0.2 0.14 12.5 0.1 1.3 1 0 0 1 1 1 0 Protein family FAM219A DDE_3 PF13358.1 EIE90003.1 - 2.4e-12 46.8 0.3 2.7e-12 46.6 0.2 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE90003.1 - 0.1 12.7 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Integrase core domain MCPVI PF02993.9 EIE90004.1 - 0.012 15.7 2.9 0.016 15.3 2.0 1.2 1 0 0 1 1 1 0 Minor capsid protein VI NUDE_C PF04880.8 EIE90004.1 - 0.029 14.7 2.8 0.045 14.1 1.9 1.3 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region DUF3580 PF12117.3 EIE90004.1 - 0.73 9.8 3.9 1.1 9.2 0.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3580) Phage_XkdX PF09693.5 EIE90005.1 - 0.031 13.8 0.0 0.053 13.0 0.0 1.3 1 0 0 1 1 1 0 Phage uncharacterised protein (Phage_XkdX) Phage_int_SAM_1 PF02899.12 EIE90006.1 - 0.15 12.2 0.0 0.6 10.3 0.0 1.9 1 1 1 2 2 2 0 Phage integrase, N-terminal SAM-like domain HTH_Tnp_Tc3_2 PF01498.13 EIE90009.1 - 6.2e-08 32.5 0.3 1.3e-07 31.5 0.2 1.5 1 0 0 1 1 1 1 Transposase HTH_Tnp_Tc3_2 PF01498.13 EIE90011.1 - 1.7e-16 60.0 1.1 3.5e-16 58.9 0.8 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.1 EIE90011.1 - 2.9e-16 59.5 0.0 5e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 EIE90011.1 - 6.9e-08 32.6 0.5 9.8e-07 28.9 0.0 2.7 3 0 0 3 3 3 1 Winged helix-turn helix HTH_23 PF13384.1 EIE90011.1 - 0.00033 20.2 0.1 0.0012 18.3 0.0 2.0 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.1 EIE90011.1 - 0.0032 17.4 0.0 0.011 15.6 0.0 2.0 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_17 PF12728.2 EIE90011.1 - 0.0071 16.5 0.8 0.25 11.5 0.0 3.0 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_38 PF13936.1 EIE90011.1 - 0.0074 15.8 0.0 0.022 14.2 0.0 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.1 EIE90011.1 - 0.0086 15.4 0.1 0.1 11.9 0.0 2.5 3 0 0 3 3 3 1 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.5 EIE90011.1 - 0.04 13.4 0.0 0.084 12.4 0.0 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_7 PF02796.10 EIE90011.1 - 0.041 13.7 0.5 0.85 9.5 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase MerR PF00376.18 EIE90011.1 - 0.065 12.7 0.3 6.1 6.4 0.0 3.0 3 0 0 3 3 3 0 MerR family regulatory protein PDEase_I PF00233.14 EIE90013.1 - 0.083 12.6 0.0 0.1 12.3 0.0 1.1 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase CD52 PF15116.1 EIE90014.1 - 0.46 10.3 3.8 0.68 9.7 2.6 1.2 1 0 0 1 1 1 0 CAMPATH-1 antigen Ribosomal_L18e PF00828.14 EIE90015.1 - 1.6e-14 54.3 0.1 1.6e-14 54.3 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 IATP PF04568.7 EIE90016.1 - 2.6e-07 30.5 1.5 2.9e-07 30.4 1.0 1.1 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP ATG16 PF08614.6 EIE90016.1 - 0.0058 16.4 0.9 0.0061 16.3 0.6 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF2188 PF09954.4 EIE90016.1 - 0.092 12.6 0.3 0.11 12.4 0.2 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2188) Vac14_Fig4_bd PF11916.3 EIE90017.1 - 7e-82 272.9 9.1 1.6e-81 271.8 6.3 1.6 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 EIE90017.1 - 5.9e-22 77.8 1.0 3.1e-16 59.5 0.0 4.7 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT PF02985.17 EIE90017.1 - 1.4e-12 46.5 0.9 0.6 10.3 0.0 6.9 6 0 0 6 6 6 4 HEAT repeat HEAT_2 PF13646.1 EIE90017.1 - 2.4e-07 30.9 0.3 4.4 7.6 0.0 5.9 5 1 0 5 5 5 3 HEAT repeats HEAT_EZ PF13513.1 EIE90017.1 - 4.7e-07 30.0 2.7 1.3 9.5 0.0 6.5 6 2 1 7 7 7 2 HEAT-like repeat Arm PF00514.18 EIE90017.1 - 5.1e-07 29.2 0.2 1.1 9.1 0.0 5.6 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat OSCP PF00213.13 EIE90018.1 - 2.4e-47 161.0 2.3 2.7e-47 160.8 1.6 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit vATP-synt_E PF01991.13 EIE90018.1 - 0.0052 16.0 1.4 0.027 13.7 0.5 1.9 1 1 1 2 2 2 1 ATP synthase (E/31 kDa) subunit SWIRM PF04433.12 EIE90019.1 - 5e-16 58.5 0.4 1.5e-15 57.0 0.0 2.0 2 0 0 2 2 2 1 SWIRM domain ZZ PF00569.12 EIE90019.1 - 6.7e-09 35.1 7.6 1.2e-08 34.3 5.3 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.26 EIE90019.1 - 9.1e-09 35.2 0.0 2.8e-08 33.6 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EIE90019.1 - 0.037 14.1 0.1 0.11 12.5 0.1 1.9 1 0 0 1 1 1 0 Myb-like DNA-binding domain Dus PF01207.12 EIE90020.1 - 1.8e-77 260.2 0.0 2.3e-77 259.8 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) SOR_SNZ PF01680.12 EIE90020.1 - 0.0046 16.5 0.2 0.017 14.7 0.1 1.9 1 1 1 2 2 2 1 SOR/SNZ family NMO PF03060.10 EIE90020.1 - 0.027 13.6 0.0 0.044 12.9 0.0 1.4 1 0 0 1 1 1 0 Nitronate monooxygenase His_biosynth PF00977.16 EIE90020.1 - 0.044 13.0 0.1 0.081 12.1 0.0 1.5 1 1 0 1 1 1 0 Histidine biosynthesis protein FMN_dh PF01070.13 EIE90020.1 - 0.044 12.6 0.0 0.072 11.9 0.0 1.3 1 0 0 1 1 1 0 FMN-dependent dehydrogenase ThiG PF05690.9 EIE90020.1 - 0.055 12.5 0.0 0.095 11.7 0.0 1.3 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG PEP_mutase PF13714.1 EIE90020.1 - 0.093 11.9 0.0 0.18 10.9 0.0 1.5 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase DHO_dh PF01180.16 EIE90020.1 - 0.1 11.5 0.0 0.2 10.5 0.0 1.4 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase FRG1 PF06229.7 EIE90021.1 - 1.1e-24 86.9 0.0 1.5e-24 86.5 0.0 1.1 1 0 0 1 1 1 1 FRG1-like family Fascin PF06268.8 EIE90021.1 - 0.0011 19.0 0.0 0.0024 17.9 0.0 1.6 1 1 0 1 1 1 1 Fascin domain DUF4137 PF13593.1 EIE90022.1 - 2.6e-86 289.5 19.2 3e-86 289.3 13.3 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.11 EIE90022.1 - 4.4e-10 39.2 14.2 4.4e-10 39.2 9.8 2.3 2 0 0 2 2 2 1 Sodium Bile acid symporter family IlvGEDA_leader PF08046.6 EIE90022.1 - 1.4 8.1 5.0 0.33 10.1 0.4 2.3 2 0 0 2 2 2 0 IlvGEDA operon leader peptide GTF2I PF02946.9 EIE90025.1 - 0.034 13.9 0.0 0.04 13.7 0.0 1.1 1 0 0 1 1 1 0 GTF2I-like repeat PMSR PF01625.16 EIE90027.1 - 5e-59 198.6 3.7 6e-59 198.3 2.5 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase PCI PF01399.22 EIE90028.1 - 1.6e-13 50.8 2.1 4.2e-13 49.5 0.0 2.6 3 1 0 3 3 3 1 PCI domain DUF1268 PF06896.6 EIE90028.1 - 0.018 15.3 2.2 0.054 13.8 1.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1268) NPV_P10 PF05531.7 EIE90028.1 - 0.021 15.0 3.7 3.2 8.0 0.1 3.0 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.6 EIE90028.1 - 0.031 14.1 0.2 0.031 14.1 0.1 3.2 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) CBM_21 PF03370.8 EIE90029.1 - 1e-18 67.3 0.1 1e-18 67.3 0.1 1.7 2 0 0 2 2 2 1 Putative phosphatase regulatory subunit MFS_1 PF07690.11 EIE90030.1 - 1.7e-30 105.9 31.3 1.3e-28 99.8 11.7 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily URO-D PF01208.12 EIE90031.1 - 3.2e-127 424.1 0.0 3.6e-127 423.9 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) DUF961 PF06125.6 EIE90032.1 - 0.09 12.9 0.1 0.18 12.0 0.1 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF961) Lentivirus_VIF PF05851.6 EIE90032.1 - 0.095 11.3 1.6 0.096 11.3 0.5 1.4 1 1 0 1 1 1 0 Lentivirus virion infectivity factor (VIF) DUF633 PF04816.7 EIE90033.1 - 0.16 11.3 0.5 0.19 11.0 0.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF633) RNB PF00773.14 EIE90034.1 - 2.3e-72 244.0 0.1 2.3e-72 244.0 0.1 1.8 2 0 0 2 2 2 1 RNB domain OB_RNB PF08206.6 EIE90034.1 - 0.011 15.2 0.0 0.026 14.0 0.0 1.6 1 0 0 1 1 1 0 Ribonuclease B OB domain DUF1869 PF08956.5 EIE90034.1 - 0.049 13.2 0.6 0.14 11.8 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1869) MCM PF00493.18 EIE90035.1 - 2.7e-136 453.7 2.0 4.7e-136 452.9 1.4 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EIE90035.1 - 7.5e-20 71.6 0.0 2.1e-19 70.1 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EIE90035.1 - 1.6e-08 34.0 0.0 1.7e-07 30.6 0.0 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EIE90035.1 - 0.00011 21.8 0.0 0.00023 20.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EIE90035.1 - 0.00013 21.4 0.0 0.00031 20.2 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.9 EIE90035.1 - 0.00027 20.6 0.0 0.00064 19.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ENTH PF01417.15 EIE90036.1 - 8.9e-32 109.5 0.1 1.3e-22 79.9 0.0 2.4 1 1 1 2 2 2 2 ENTH domain ANTH PF07651.11 EIE90036.1 - 0.00099 17.8 0.5 0.0019 16.9 0.4 1.5 1 0 0 1 1 1 1 ANTH domain UIM PF02809.15 EIE90036.1 - 0.0036 16.7 5.7 0.05 13.1 0.3 2.8 2 0 0 2 2 2 2 Ubiquitin interaction motif GCR1_C PF12550.3 EIE90037.1 - 5.1e-26 90.3 0.7 5.1e-25 87.1 0.2 2.6 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes ADH_N PF08240.7 EIE90038.1 - 1e-26 92.7 3.1 1.7e-26 92.1 2.2 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIE90038.1 - 8.9e-11 41.4 0.0 2.1e-09 37.0 0.0 2.5 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIE90038.1 - 0.00024 21.9 0.0 0.0006 20.7 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EIE90038.1 - 0.0076 15.4 0.0 0.018 14.2 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.13 EIE90038.1 - 0.095 12.7 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain ADH_N_assoc PF13823.1 EIE90038.1 - 4.8 6.9 5.4 3 7.6 0.1 2.7 3 0 0 3 3 3 0 Alcohol dehydrogenase GroES-associated CBS PF00571.23 EIE90039.1 - 0.0003 20.4 0.1 0.00044 19.9 0.0 1.2 1 0 0 1 1 1 1 CBS domain RVT_1 PF00078.22 EIE90040.1 - 3.9e-12 45.9 0.1 5.8e-12 45.4 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1204 PF06721.6 EIE90040.1 - 0.042 13.1 0.0 0.066 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1204) FlxA PF14282.1 EIE90041.1 - 0.076 12.9 0.7 0.11 12.5 0.5 1.2 1 0 0 1 1 1 0 FlxA-like protein EamA PF00892.15 EIE90042.1 - 3.1e-23 82.1 27.3 4.2e-15 55.8 6.9 2.9 2 1 1 3 3 3 2 EamA-like transporter family EmrE PF13536.1 EIE90042.1 - 6.6e-06 26.3 10.6 6.6e-06 26.3 7.4 3.5 2 2 1 3 3 3 2 Multidrug resistance efflux transporter Nuc_sug_transp PF04142.10 EIE90042.1 - 0.0015 17.6 1.6 0.003 16.7 1.1 1.5 1 0 0 1 1 1 1 Nucleotide-sugar transporter zf-RVT PF13966.1 EIE90044.1 - 5.4e-06 26.6 0.3 7.9e-06 26.1 0.2 1.2 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase LsmAD PF06741.8 EIE90045.1 - 9e-24 83.3 0.0 9e-24 83.3 0.0 2.8 2 1 1 3 3 3 1 LsmAD domain SM-ATX PF14438.1 EIE90045.1 - 6.6e-16 57.9 0.0 1.9e-15 56.5 0.0 1.8 1 0 0 1 1 1 1 Ataxin 2 SM domain PAM2 PF07145.10 EIE90045.1 - 0.94 9.1 7.2 4 7.1 0.4 2.9 3 0 0 3 3 3 0 Ataxin-2 C-terminal region CBS PF00571.23 EIE90046.1 - 2.3e-36 123.2 5.6 4.2e-10 39.2 0.0 4.6 4 0 0 4 4 4 4 CBS domain PB1 PF00564.19 EIE90046.1 - 9.7e-07 28.3 1.1 7.3e-06 25.5 0.8 2.3 1 1 0 1 1 1 1 PB1 domain KaiC PF06745.8 EIE90046.1 - 0.092 11.8 0.0 0.19 10.8 0.0 1.5 1 0 0 1 1 1 0 KaiC 6PF2K PF01591.13 EIE90047.1 - 4.9e-82 274.3 0.0 6.5e-82 273.9 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EIE90047.1 - 7.2e-26 91.1 0.0 2.1e-25 89.6 0.0 1.8 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EIE90047.1 - 8.7e-07 28.9 0.0 1.5e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EIE90047.1 - 0.0029 18.3 0.5 0.021 15.6 0.0 2.5 2 1 0 2 2 2 1 AAA domain Pkinase PF00069.20 EIE90048.1 - 3.7e-68 229.4 0.7 1.2e-67 227.8 0.0 2.1 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE90048.1 - 1.4e-48 165.2 0.0 2.3e-48 164.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 EIE90048.1 - 5.1e-25 87.4 1.1 9.2e-25 86.6 0.2 1.8 2 0 0 2 2 2 1 Ras-binding domain of Byr2 RA PF00788.18 EIE90048.1 - 3.3e-10 40.3 0.0 8.2e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Kinase-like PF14531.1 EIE90048.1 - 2.7e-09 36.3 0.0 4e-08 32.5 0.0 2.2 2 0 0 2 2 2 1 Kinase-like BCDHK_Adom3 PF10436.4 EIE90049.1 - 3e-45 153.6 0.8 4.6e-45 153.0 0.6 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EIE90049.1 - 3.7e-16 58.8 0.0 6.9e-16 57.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EIE90049.1 - 0.00021 20.9 0.0 0.00038 20.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 EIE90049.1 - 0.0086 15.8 0.1 0.064 13.0 0.0 2.0 1 1 1 2 2 2 1 Histidine kinase-like ATPase domain AAA_assoc PF14363.1 EIE90049.1 - 0.076 13.0 0.1 0.42 10.7 0.0 2.2 2 1 0 2 2 2 0 Domain associated at C-terminal with AAA zf-RVT PF13966.1 EIE90051.1 - 5.6e-06 26.5 2.2 5.6e-06 26.5 1.5 1.8 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase Nol1_Nop2_Fmu PF01189.12 EIE90051.1 - 0.12 11.7 0.1 6.8 5.9 0.0 2.2 1 1 1 2 2 2 0 NOL1/NOP2/sun family LIF_OSM PF01291.12 EIE90053.1 - 0.0069 16.3 0.0 0.011 15.6 0.0 1.4 1 1 0 1 1 1 1 LIF / OSM family Lzipper-MIP1 PF14389.1 EIE90053.1 - 0.085 12.9 0.1 0.16 12.1 0.1 1.4 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 zf-RVT PF13966.1 EIE90054.1 - 2.7e-05 24.3 3.3 3.2e-05 24.1 0.8 2.2 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase PhageP22-tail PF09251.5 EIE90055.1 - 0.12 10.5 0.0 0.14 10.4 0.0 1.1 1 0 0 1 1 1 0 Salmonella phage P22 tail-spike Rtt102p PF09510.5 EIE90056.1 - 0.02 14.8 0.1 0.024 14.6 0.0 1.2 1 0 0 1 1 1 0 Rtt102p-like transcription regulator protein DUF4545 PF15078.1 EIE90056.1 - 0.082 11.8 0.1 0.084 11.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4545) DDE_3 PF13358.1 EIE90057.1 - 2.8e-12 46.6 0.3 3.5e-12 46.2 0.2 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE90057.1 - 0.11 12.5 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Integrase core domain zf-CCHC_4 PF14392.1 EIE90058.1 - 0.23 11.1 4.8 0.28 10.8 0.4 2.5 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC PF00098.18 EIE90058.1 - 0.43 10.5 0.1 0.43 10.5 0.1 1.9 2 0 0 2 2 2 0 Zinc knuckle FYDLN_acid PF09538.5 EIE90058.1 - 6.2 7.4 8.8 12 6.5 6.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) HTH_Tnp_Tc3_2 PF01498.13 EIE90059.1 - 1e-11 44.6 2.1 1.1e-11 44.5 0.6 1.8 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.1 EIE90059.1 - 0.0012 18.4 0.3 0.0036 16.9 0.0 2.0 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.1 EIE90059.1 - 0.028 14.5 0.3 0.067 13.3 0.0 1.8 2 0 0 2 2 2 0 Winged helix-turn helix HTH_30 PF13556.1 EIE90059.1 - 0.054 13.0 0.0 0.36 10.4 0.0 2.0 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain RecX PF02631.11 EIE90059.1 - 0.1 12.7 0.2 0.17 12.1 0.1 1.3 1 0 0 1 1 1 0 RecX family DUF3713 PF12506.3 EIE90060.1 - 0.00012 22.1 0.4 0.00025 21.0 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3713) TGS PF02824.16 EIE90060.1 - 0.0074 16.1 0.0 3.1 7.7 0.0 2.9 2 1 0 2 2 2 2 TGS domain Transposase_21 PF02992.9 EIE90060.1 - 0.017 14.2 0.0 0.032 13.3 0.0 1.4 1 0 0 1 1 1 0 Transposase family tnp2 DDE_3 PF13358.1 EIE90061.1 - 2.5e-13 50.0 0.0 3.8e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_23 PF13384.1 EIE90061.1 - 0.01 15.4 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain GcrA PF07750.6 EIE90061.1 - 0.017 15.3 0.1 0.028 14.6 0.0 1.4 1 0 0 1 1 1 0 GcrA cell cycle regulator HTH_7 PF02796.10 EIE90061.1 - 0.021 14.6 0.1 0.05 13.4 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase DUF2567 PF10821.3 EIE90061.1 - 0.079 12.4 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2567) HTH_20 PF12840.2 EIE90061.1 - 0.084 12.6 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Transposase_21 PF02992.9 EIE90062.1 - 0.0015 17.6 0.0 0.0026 16.8 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DUF1648 PF07853.6 EIE90064.1 - 0.093 12.2 0.1 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1648) RVT_1 PF00078.22 EIE90066.1 - 8.3e-28 97.2 0.0 1.2e-27 96.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Serglycin PF04360.7 EIE90066.1 - 1.6 8.4 15.0 0.078 12.7 4.5 2.4 2 0 0 2 2 2 0 Serglycin Exo_endo_phos PF03372.18 EIE90067.1 - 6.6e-05 22.9 0.0 0.00024 21.1 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EIE90067.1 - 0.0054 16.3 0.0 0.016 14.7 0.0 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase SYCE1 PF15233.1 EIE90067.1 - 0.015 15.2 0.5 0.023 14.5 0.4 1.2 1 0 0 1 1 1 0 Synaptonemal complex central element protein 1 DUF972 PF06156.8 EIE90067.1 - 0.083 13.2 0.4 0.13 12.5 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF3450 PF11932.3 EIE90067.1 - 0.087 12.0 0.5 0.14 11.4 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Lzipper-MIP1 PF14389.1 EIE90068.1 - 0.0063 16.5 0.4 0.017 15.2 0.3 1.7 1 0 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 ChaB PF06150.7 EIE90068.1 - 0.08 12.7 0.4 0.31 10.8 0.1 2.1 2 0 0 2 2 2 0 ChaB SRR PF07709.6 EIE90068.1 - 0.39 11.0 4.4 6.7 7.3 0.0 3.5 3 0 0 3 3 3 0 Seven Residue Repeat HTH_Tnp_Tc3_2 PF01498.13 EIE90069.1 - 3.1e-09 36.7 0.8 1.5e-08 34.5 0.7 2.1 2 1 1 3 3 3 1 Transposase DDE_3 PF13358.1 EIE90069.1 - 1.3e-07 31.5 0.0 3e-07 30.3 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_Tnp_IS1595 PF12762.2 EIE90070.1 - 5.9e-10 39.1 0.0 1.9e-09 37.5 0.0 1.8 2 0 0 2 2 2 1 ISXO2-like transposase domain CDC45 PF02724.9 EIE90072.1 - 0.56 8.1 6.3 0.64 7.9 4.3 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4611 PF15387.1 EIE90072.1 - 0.62 10.2 7.3 0.49 10.5 3.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) YL1 PF05764.8 EIE90072.1 - 2.9 7.4 8.5 3.4 7.2 5.9 1.1 1 0 0 1 1 1 0 YL1 nuclear protein DDE_3 PF13358.1 EIE90073.1 - 2.8e-21 75.7 1.0 3.4e-21 75.5 0.3 1.4 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE90075.1 - 6.1e-09 35.8 0.5 8.4e-09 35.3 0.3 1.2 1 0 0 1 1 1 1 Transposase Atg8 PF02991.11 EIE90075.1 - 0.12 12.3 0.1 0.18 11.8 0.1 1.3 1 0 0 1 1 1 0 Autophagy protein Atg8 ubiquitin like KRTAP PF11759.3 EIE90078.1 - 0.0032 17.6 26.1 0.0037 17.4 18.1 1.2 1 0 0 1 1 1 1 Keratin-associated matrix DUF2847 PF11009.3 EIE90079.1 - 0.069 12.7 0.1 0.069 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) DUF2847 PF11009.3 EIE90086.1 - 0.069 12.7 0.1 0.069 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) rve PF00665.21 EIE90091.1 - 1.1e-18 67.4 0.0 2.3e-18 66.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE90091.1 - 5.5e-17 61.8 0.2 1.2e-16 60.7 0.2 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE90091.1 - 3.6e-13 48.9 1.0 1e-12 47.4 0.7 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVP PF00077.15 EIE90091.1 - 0.00045 20.0 0.1 0.0018 18.1 0.1 2.1 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 EIE90091.1 - 0.00046 20.6 0.0 0.0011 19.4 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease DUF1068 PF06364.7 EIE90094.1 - 0.13 11.8 0.6 0.17 11.4 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1068) HTH_Tnp_Tc3_2 PF01498.13 EIE90095.1 - 0.0056 16.7 0.1 0.0084 16.1 0.0 1.2 1 0 0 1 1 1 1 Transposase SIS PF01380.17 EIE90096.1 - 4.2e-60 201.0 0.1 5.2e-32 110.2 0.1 2.4 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 EIE90096.1 - 1.8e-26 92.7 0.1 7.1e-19 67.7 0.0 2.2 2 0 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EIE90096.1 - 2.9e-19 69.3 0.0 6.9e-19 68.1 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EIE90096.1 - 3.4e-14 52.6 0.0 7.2e-14 51.6 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 EIE90096.1 - 3.3e-08 32.5 0.0 6.1e-08 31.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 EIE90096.1 - 0.00024 20.8 0.0 0.00077 19.1 0.0 2.0 2 0 0 2 2 2 1 SIS domain zf-Tim10_DDP PF02953.10 EIE90097.1 - 1.7e-18 65.6 1.7 1.9e-18 65.4 1.2 1.0 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 EIE90097.1 - 0.013 14.9 2.0 0.025 14.0 1.4 1.5 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) zf-RING_UBOX PF13445.1 EIE90098.1 - 0.00018 21.1 0.5 0.00043 19.9 0.3 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.1 EIE90098.1 - 0.00024 20.8 0.4 0.00045 19.9 0.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EIE90098.1 - 0.014 15.0 1.1 0.022 14.4 0.8 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIE90098.1 - 0.015 15.2 0.5 0.027 14.5 0.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2616 PF11077.3 EIE90098.1 - 0.052 13.0 0.3 0.097 12.1 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2616) zf-rbx1 PF12678.2 EIE90098.1 - 0.094 12.8 2.1 0.42 10.7 1.4 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EIE90098.1 - 0.1 12.2 0.5 0.18 11.5 0.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FH2 PF02181.18 EIE90099.1 - 8.5e-55 186.1 28.4 5e-48 163.8 4.4 3.3 3 1 0 3 3 3 2 Formin Homology 2 Domain Drf_GBD PF06371.8 EIE90099.1 - 9.5e-33 113.1 0.7 3.3e-32 111.3 0.5 2.0 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 EIE90099.1 - 9.9e-23 80.5 2.4 9.9e-23 80.5 1.6 2.4 2 1 0 2 2 2 1 Diaphanous FH3 Domain DUF1752 PF08550.5 EIE90100.1 - 2.9e-10 39.5 2.3 5.4e-10 38.6 1.6 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) DNA_primase_lrg PF04104.9 EIE90101.1 - 2.8e-84 282.4 0.2 2.8e-84 282.4 0.1 2.9 3 1 1 4 4 4 1 Eukaryotic and archaeal DNA primase, large subunit RabGAP-TBC PF00566.13 EIE90101.1 - 5.3e-31 107.7 8.7 1.2e-26 93.5 1.7 3.4 2 1 1 3 3 3 2 Rab-GTPase-TBC domain Ribosomal_L23eN PF03939.8 EIE90102.1 - 1.8e-20 72.6 13.1 3.8e-20 71.6 9.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.15 EIE90102.1 - 2.1e-19 69.2 2.5 2.1e-19 69.2 1.8 1.9 2 0 0 2 2 2 1 Ribosomal protein L23 WD40 PF00400.27 EIE90103.1 - 4.7e-34 115.0 13.6 3.3e-09 36.2 0.1 6.3 6 1 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 EIE90103.1 - 6.7e-07 29.2 2.0 0.00018 21.2 0.8 2.9 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 EIE90103.1 - 0.0066 14.3 0.6 0.083 10.6 0.0 2.1 2 0 0 2 2 2 1 IKI3 family HPS3_N PF14761.1 EIE90103.1 - 0.07 12.5 0.0 0.21 10.9 0.0 1.7 2 0 0 2 2 2 0 Hermansky-Pudlak syndrome 3 G-patch PF01585.18 EIE90104.1 - 4.4e-11 42.3 1.1 1.1e-10 41.0 0.8 1.8 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EIE90104.1 - 0.0088 15.8 0.7 0.0088 15.8 0.5 2.5 3 0 0 3 3 3 1 DExH-box splicing factor binding site Fungal_trans PF04082.13 EIE90105.1 - 7.7e-43 146.2 0.2 7.7e-43 146.2 0.1 2.0 3 0 0 3 3 3 1 Fungal specific transcription factor domain Ribosomal_S26e PF01283.14 EIE90106.1 - 2e-25 89.2 1.4 2.1e-25 89.1 1.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e ABC_membrane PF00664.18 EIE90107.1 - 8.7e-57 192.6 34.2 3.3e-30 105.4 2.7 3.2 4 0 0 4 4 3 2 ABC transporter transmembrane region ABC_tran PF00005.22 EIE90107.1 - 2.4e-52 176.8 0.0 8.2e-31 107.1 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EIE90107.1 - 1.6e-09 37.3 3.8 0.00046 19.4 0.1 4.2 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain T2SE PF00437.15 EIE90107.1 - 5.9e-07 28.6 0.0 0.0082 15.0 0.1 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_25 PF13481.1 EIE90107.1 - 8.7e-07 28.5 0.2 0.04 13.3 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_23 PF13476.1 EIE90107.1 - 1.8e-06 28.3 0.5 0.0024 18.2 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_29 PF13555.1 EIE90107.1 - 5.4e-06 25.8 0.8 0.068 12.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EIE90107.1 - 6.7e-06 26.9 0.0 0.17 12.7 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EIE90107.1 - 7.2e-06 25.9 0.0 0.01 15.6 0.0 3.6 3 0 0 3 3 3 1 AAA domain DUF87 PF01935.12 EIE90107.1 - 2.6e-05 24.1 0.6 0.073 12.8 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function DUF87 AAA_18 PF13238.1 EIE90107.1 - 6.5e-05 23.2 0.0 0.78 10.0 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.1 EIE90107.1 - 7.8e-05 22.7 8.4 0.41 10.5 0.1 4.6 5 1 0 5 5 3 2 AAA domain AAA_22 PF13401.1 EIE90107.1 - 0.0001 22.4 3.0 0.1 12.7 0.0 3.4 2 1 0 2 2 2 1 AAA domain MobB PF03205.9 EIE90107.1 - 0.00012 21.7 0.6 0.23 11.1 0.1 2.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 EIE90107.1 - 0.00015 22.2 0.1 0.17 12.4 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein AAA_10 PF12846.2 EIE90107.1 - 0.00019 20.9 0.9 0.25 10.7 0.1 2.4 2 0 0 2 2 2 2 AAA-like domain FtsK_SpoIIIE PF01580.13 EIE90107.1 - 0.0012 18.3 0.0 1.7 8.0 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family NACHT PF05729.7 EIE90107.1 - 0.0015 18.2 0.7 0.26 10.9 0.1 2.7 2 0 0 2 2 2 1 NACHT domain DUF258 PF03193.11 EIE90107.1 - 0.0016 17.6 0.1 0.23 10.6 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_14 PF13173.1 EIE90107.1 - 0.0016 18.2 0.4 2.3 8.1 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 EIE90107.1 - 0.0021 18.0 1.0 2.1 8.2 0.1 2.5 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.18 EIE90107.1 - 0.0031 17.4 0.8 0.64 9.9 0.1 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase ResIII PF04851.10 EIE90107.1 - 0.0042 16.9 0.0 2.2 8.0 0.0 2.6 3 0 0 3 3 2 1 Type III restriction enzyme, res subunit Zeta_toxin PF06414.7 EIE90107.1 - 0.0055 15.8 0.3 2.5 7.1 0.1 3.0 3 0 0 3 3 3 1 Zeta toxin AAA_19 PF13245.1 EIE90107.1 - 0.0058 16.3 0.5 0.079 12.7 0.1 2.7 2 0 0 2 2 2 1 Part of AAA domain Pox_A32 PF04665.7 EIE90107.1 - 0.0066 15.7 0.5 2.9 7.1 0.0 2.4 2 0 0 2 2 2 1 Poxvirus A32 protein Dynamin_N PF00350.18 EIE90107.1 - 0.01 15.6 0.5 0.69 9.7 0.0 2.5 2 0 0 2 2 2 0 Dynamin family IstB_IS21 PF01695.12 EIE90107.1 - 0.016 14.6 0.8 10 5.4 0.0 3.3 4 0 0 4 4 3 0 IstB-like ATP binding protein AAA PF00004.24 EIE90107.1 - 0.032 14.4 0.6 4.7 7.4 0.1 3.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.14 EIE90107.1 - 0.048 13.1 3.2 0.18 11.2 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.17 EIE90107.1 - 0.061 13.5 0.5 19 5.4 0.0 2.8 3 0 0 3 3 2 0 RNA helicase SbcCD_C PF13558.1 EIE90107.1 - 0.065 13.1 0.0 16 5.4 0.0 3.0 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit NB-ARC PF00931.17 EIE90107.1 - 0.081 11.7 3.2 1.2 7.8 0.0 3.2 4 0 0 4 4 3 0 NB-ARC domain DEAD PF00270.24 EIE90107.1 - 0.089 12.2 0.2 3 7.3 0.0 2.9 3 0 0 3 3 3 0 DEAD/DEAH box helicase ATP_bind_1 PF03029.12 EIE90107.1 - 0.094 12.2 5.4 3 7.2 0.1 3.7 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein AAA_24 PF13479.1 EIE90107.1 - 0.11 12.0 0.9 2.4 7.7 0.2 2.3 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.4 EIE90107.1 - 0.11 11.0 0.3 6.2 5.3 0.1 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_30 PF13604.1 EIE90107.1 - 0.21 11.1 0.3 7.9 6.0 0.0 3.0 3 0 0 3 3 3 0 AAA domain SRP54 PF00448.17 EIE90107.1 - 0.22 10.9 0.6 3.1 7.2 0.1 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF106 PF01956.11 EIE90107.1 - 1.4 8.4 9.6 0.047 13.2 1.5 2.3 2 0 0 2 2 2 0 Integral membrane protein DUF106 Alginate_lyase PF05426.7 EIE90108.1 - 7.9e-35 120.5 0.0 9.8e-35 120.2 0.0 1.1 1 0 0 1 1 1 1 Alginate lyase OKR_DC_1_N PF03709.10 EIE90110.1 - 0.02 14.9 0.1 0.15 12.1 0.0 2.0 1 1 1 2 2 2 0 Orn/Lys/Arg decarboxylase, N-terminal domain PseudoU_synth_1 PF01416.15 EIE90111.1 - 1.6e-27 96.0 0.0 2.8e-15 56.6 0.0 2.5 2 0 0 2 2 2 2 tRNA pseudouridine synthase Abhydrolase_3 PF07859.8 EIE90112.1 - 2.3e-16 60.0 0.0 3e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Glyco_transf_20 PF00982.16 EIE90113.1 - 2.7e-198 659.2 0.0 3.3e-198 658.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EIE90113.1 - 6.2e-43 146.3 0.0 1.7e-42 144.9 0.0 1.7 1 1 0 1 1 1 1 Trehalose-phosphatase Glycos_transf_1 PF00534.15 EIE90113.1 - 0.0052 16.2 0.0 0.26 10.7 0.0 3.1 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 EIE90113.1 - 0.032 13.7 0.1 0.07 12.6 0.1 1.5 1 0 0 1 1 1 0 Starch synthase catalytic domain PGP_phosphatase PF09419.5 EIE90113.1 - 0.11 11.8 0.1 1.4 8.2 0.0 2.8 4 0 0 4 4 4 0 Mitochondrial PGP phosphatase Ribosomal_L7Ae PF01248.21 EIE90114.1 - 6e-23 80.1 1.7 1.1e-22 79.3 1.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 EIE90114.1 - 0.013 15.3 0.2 0.025 14.3 0.1 1.5 1 1 0 1 1 1 0 RNase P subunit Pop3 Arch_ATPase PF01637.13 EIE90114.1 - 0.021 14.5 0.4 0.036 13.7 0.3 1.3 1 0 0 1 1 1 0 Archaeal ATPase cNMP_binding PF00027.24 EIE90116.1 - 1.2e-42 143.5 0.1 2.2e-20 72.2 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.12 EIE90116.1 - 2.6e-10 39.5 1.0 5e-10 38.6 0.7 1.5 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Septin PF00735.13 EIE90117.1 - 1.7e-111 371.7 0.7 2.4e-111 371.2 0.5 1.2 1 0 0 1 1 1 1 Septin GTP_EFTU PF00009.22 EIE90117.1 - 5.9e-08 32.3 0.9 4.7e-06 26.1 0.0 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EIE90117.1 - 4.3e-07 29.8 0.0 8.6e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EIE90117.1 - 6e-07 28.7 0.3 2e-06 27.1 0.2 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 EIE90117.1 - 9.7e-05 22.8 0.4 0.00029 21.2 0.2 2.1 1 1 0 1 1 1 1 Miro-like protein AAA_22 PF13401.1 EIE90117.1 - 0.00034 20.7 0.7 0.00098 19.2 0.0 2.3 2 2 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EIE90117.1 - 0.00066 19.5 0.2 0.0045 16.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 EIE90117.1 - 0.0035 16.8 0.1 0.0095 15.4 0.1 1.7 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_10 PF12846.2 EIE90117.1 - 0.0035 16.8 0.0 0.0076 15.7 0.0 1.5 1 1 0 1 1 1 1 AAA-like domain Sigma54_activat PF00158.21 EIE90117.1 - 0.0046 16.4 0.0 0.0084 15.5 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain RNA_helicase PF00910.17 EIE90117.1 - 0.0047 17.0 0.5 0.019 15.1 0.0 2.2 2 1 0 2 2 1 1 RNA helicase Dynamin_N PF00350.18 EIE90117.1 - 0.0049 16.7 7.2 0.28 10.9 0.0 3.2 2 1 1 3 3 3 2 Dynamin family IIGP PF05049.8 EIE90117.1 - 0.0052 15.6 0.1 0.011 14.5 0.1 1.6 1 1 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AAA_24 PF13479.1 EIE90117.1 - 0.0053 16.3 0.0 0.011 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AIG1 PF04548.11 EIE90117.1 - 0.0061 15.6 0.1 0.017 14.1 0.1 1.8 1 0 0 1 1 1 1 AIG1 family Ras PF00071.17 EIE90117.1 - 0.0083 15.5 0.2 0.031 13.6 0.1 2.0 1 1 0 1 1 1 1 Ras family NTPase_1 PF03266.10 EIE90117.1 - 0.0088 15.7 1.8 0.64 9.7 0.4 2.5 2 0 0 2 2 2 1 NTPase PduV-EutP PF10662.4 EIE90117.1 - 0.011 15.1 0.8 1.6 8.2 0.0 3.0 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.22 EIE90117.1 - 0.012 15.9 1.4 0.066 13.5 0.0 2.3 2 0 0 2 2 2 0 ABC transporter Dynamitin PF04912.9 EIE90117.1 - 0.015 14.1 6.0 0.028 13.2 4.1 1.4 1 0 0 1 1 1 0 Dynamitin AAA_16 PF13191.1 EIE90117.1 - 0.02 14.8 0.4 0.094 12.6 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain ATP_bind_1 PF03029.12 EIE90117.1 - 0.028 13.9 1.5 0.81 9.1 0.1 3.1 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein AAA_18 PF13238.1 EIE90117.1 - 0.029 14.6 1.7 0.11 12.8 0.0 2.6 2 1 0 2 2 2 0 AAA domain Pox_A32 PF04665.7 EIE90117.1 - 0.032 13.5 0.4 0.077 12.2 0.0 1.8 2 0 0 2 2 2 0 Poxvirus A32 protein NACHT PF05729.7 EIE90117.1 - 0.045 13.3 0.0 0.098 12.3 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Cut12 PF11500.3 EIE90117.1 - 0.065 12.9 7.0 0.14 11.8 4.8 1.6 1 0 0 1 1 1 0 Spindle pole body formation-associated protein MobB PF03205.9 EIE90117.1 - 0.072 12.7 0.2 0.15 11.7 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Dus PF01207.12 EIE90117.1 - 0.074 11.8 0.0 0.074 11.8 0.0 2.1 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) AAA_29 PF13555.1 EIE90117.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain PRK PF00485.13 EIE90117.1 - 0.18 11.3 2.3 0.19 11.2 0.0 2.0 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family T2SE PF00437.15 EIE90117.1 - 0.55 9.0 3.8 0.16 10.8 0.3 1.8 3 0 0 3 3 3 0 Type II/IV secretion system protein Mnd1 PF03962.10 EIE90117.1 - 1.2 8.7 11.0 2.7 7.5 7.1 2.0 2 0 0 2 2 2 0 Mnd1 family AAA_17 PF13207.1 EIE90117.1 - 1.6 9.5 4.3 0.73 10.6 0.1 2.6 2 2 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EIE90117.1 - 4.4 7.5 17.6 1.5e+02 2.5 12.2 2.3 1 1 0 1 1 1 0 AAA domain APG6 PF04111.7 EIE90117.1 - 9.3 5.1 13.1 14 4.5 9.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Glycos_transf_1 PF00534.15 EIE90118.1 - 1.3e-16 60.5 0.0 9.2e-16 57.7 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EIE90118.1 - 0.0067 16.5 0.0 0.17 12.0 0.0 2.3 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EIE90118.1 - 0.13 12.4 0.0 1.2 9.2 0.0 2.2 1 1 1 2 2 2 0 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.1 EIE90118.1 - 0.13 11.9 0.1 5 6.8 0.1 2.3 1 1 0 1 1 1 0 Glycosyltransferase Family 4 Mito_carr PF00153.22 EIE90119.1 - 2.6e-64 212.9 3.2 1.5e-21 75.9 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.14 EIE90119.1 - 0.024 14.6 0.1 0.38 10.7 0.0 2.5 2 0 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family Ribosomal_L23 PF00276.15 EIE90120.1 - 1.1e-17 63.7 0.0 2.1e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L23 DOT1 PF08123.8 EIE90121.1 - 4.1e-47 160.1 0.1 6.4e-30 104.0 0.0 2.2 1 1 1 2 2 2 2 Histone methylation protein DOT1 Methyltransf_31 PF13847.1 EIE90121.1 - 1.4e-05 24.7 0.1 4e-05 23.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIE90121.1 - 2.7e-05 24.1 0.0 4.3e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIE90121.1 - 0.00015 22.2 0.0 0.00026 21.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EIE90121.1 - 0.00044 19.4 0.0 0.00065 18.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase AdoMet_MTase PF07757.8 EIE90121.1 - 0.0012 18.9 0.0 0.0039 17.3 0.0 1.9 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_11 PF08241.7 EIE90121.1 - 0.0018 18.7 0.0 0.0033 17.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIE90121.1 - 0.0022 17.7 0.0 0.004 16.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIE90121.1 - 0.0033 17.8 0.0 0.0069 16.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EIE90121.1 - 0.0061 15.6 0.0 0.012 14.6 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 EIE90121.1 - 0.021 14.1 0.0 0.03 13.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain MetW PF07021.7 EIE90121.1 - 0.023 14.0 0.0 0.042 13.2 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW SWIRM PF04433.12 EIE90122.1 - 9.6e-33 112.1 0.1 9.6e-33 112.1 0.1 2.8 3 1 0 3 3 3 1 SWIRM domain Myb_DNA-binding PF00249.26 EIE90122.1 - 5.9e-12 45.4 0.4 5.9e-12 45.4 0.3 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EIE90122.1 - 3.5e-08 33.4 1.3 3.6e-07 30.1 0.1 2.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Pkinase PF00069.20 EIE90123.1 - 3.4e-46 157.4 0.0 1e-39 136.2 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIE90123.1 - 8.9e-34 116.7 0.0 1.2e-28 99.9 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EIE90123.1 - 0.0012 17.9 0.0 0.0062 15.5 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Smr PF01713.16 EIE90124.1 - 2.3e-12 46.9 0.0 8.6e-12 45.0 0.0 2.1 1 0 0 1 1 1 1 Smr domain CUE PF02845.11 EIE90124.1 - 7.3e-08 31.7 0.2 0.00037 19.9 0.1 2.5 2 0 0 2 2 2 2 CUE domain DUF1771 PF08590.5 EIE90124.1 - 1.9e-06 27.8 0.9 1.9e-06 27.8 0.7 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) FNIP_M PF14637.1 EIE90124.1 - 0.038 13.5 0.2 0.98 8.9 0.0 2.4 2 0 0 2 2 2 0 Folliculin-interacting protein middle domain DMA PF03474.9 EIE90124.1 - 0.078 12.8 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 DMRTA motif RVT_1 PF00078.22 EIE90125.1 - 1e-33 116.5 0.0 1.8e-33 115.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) NumbF PF06311.7 EIE90125.1 - 0.036 14.1 0.1 0.28 11.3 0.0 2.5 2 0 0 2 2 2 0 NUMB domain Herpes_BLRF2 PF05812.7 EIE90126.1 - 0.029 14.1 0.2 3.4 7.4 0.1 2.5 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein SWIM PF04434.12 EIE90127.1 - 0.0096 15.3 0.8 0.018 14.4 0.5 1.4 1 0 0 1 1 1 1 SWIM zinc finger Pepsin-I3 PF06394.8 EIE90127.1 - 0.11 12.1 0.1 0.18 11.4 0.1 1.3 1 0 0 1 1 1 0 Pepsin inhibitor-3-like repeated domain Dsh_C PF12316.3 EIE90128.1 - 0.065 13.3 0.9 0.072 13.1 0.6 1.0 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Dehydrin PF00257.14 EIE90128.1 - 0.096 13.0 0.0 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 Dehydrin LON PF02190.11 EIE90128.1 - 0.14 11.8 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 ATP-dependent protease La (LON) domain DUF4589 PF15252.1 EIE90128.1 - 0.16 11.7 1.0 0.19 11.5 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4589) Ribosomal_S4e PF00900.15 EIE90129.1 - 6.3e-34 115.4 2.2 3.1e-33 113.2 0.6 2.3 2 0 0 2 2 2 1 Ribosomal family S4e RS4NT PF08071.7 EIE90129.1 - 1.6e-19 69.4 5.5 1.4e-18 66.4 4.6 2.0 2 0 0 2 2 2 1 RS4NT (NUC023) domain S4 PF01479.20 EIE90129.1 - 3.5e-06 26.3 0.0 7e-06 25.3 0.0 1.6 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 EIE90129.1 - 0.00034 20.2 2.7 0.00034 20.2 1.9 3.4 4 0 0 4 4 4 1 KOW motif YflT PF11181.3 EIE90130.1 - 0.067 13.3 0.1 0.077 13.1 0.1 1.1 1 0 0 1 1 1 0 Heat induced stress protein YflT DUF3018 PF11455.3 EIE90130.1 - 3.9 7.4 5.6 1.1 9.2 1.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3018) WD40 PF00400.27 EIE90131.1 - 4.4e-43 143.6 11.6 9.4e-09 34.8 0.4 5.4 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 EIE90131.1 - 3.1e-06 25.6 6.9 0.00032 18.9 0.1 3.9 1 1 3 4 4 4 3 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 EIE90131.1 - 0.00096 18.9 0.0 0.7 9.6 0.0 3.2 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region F-box-like PF12937.2 EIE90131.1 - 0.0054 16.4 0.1 0.013 15.2 0.1 1.6 1 0 0 1 1 1 1 F-box-like Cytochrom_D1 PF02239.11 EIE90131.1 - 0.017 13.4 0.1 0.19 9.9 0.0 2.1 1 1 0 2 2 2 0 Cytochrome D1 heme domain Urease_beta PF00699.15 EIE90131.1 - 0.14 11.9 0.0 0.35 10.7 0.0 1.7 1 0 0 1 1 1 0 Urease beta subunit GIT_SHD PF08518.6 EIE90132.1 - 1.3e-17 62.8 3.6 1.8e-11 43.2 0.2 2.7 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT Rootletin PF15035.1 EIE90132.1 - 0.004 17.1 10.3 0.004 17.1 7.2 2.2 2 0 0 2 2 2 1 Ciliary rootlet component, centrosome cohesion CCD PF07860.6 EIE90132.1 - 0.024 14.0 1.1 0.054 12.9 0.2 2.0 2 0 0 2 2 2 0 WisP family C-Terminal Region DivIC PF04977.10 EIE90132.1 - 0.11 12.0 7.0 0.41 10.1 4.3 2.5 1 1 1 2 2 2 0 Septum formation initiator DUF3450 PF11932.3 EIE90132.1 - 0.22 10.7 10.4 0.032 13.4 4.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF904 PF06005.7 EIE90132.1 - 0.4 11.0 21.4 0.15 12.3 10.1 3.3 2 1 0 2 2 2 0 Protein of unknown function (DUF904) APG6 PF04111.7 EIE90132.1 - 0.41 9.6 15.6 0.11 11.5 8.3 1.9 2 0 0 2 2 2 0 Autophagy protein Apg6 Mod_r PF07200.8 EIE90132.1 - 0.77 9.6 15.7 0.91 9.4 6.6 3.5 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein TPR_14 PF13428.1 EIE90133.1 - 0.0091 16.5 0.2 0.024 15.2 0.2 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat Ribosomal_L11_N PF03946.9 EIE90135.1 - 2.2e-18 65.4 0.1 4.6e-18 64.4 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 EIE90135.1 - 1.7e-12 47.2 0.1 2.9e-12 46.5 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain IF2_N PF04760.10 EIE90135.1 - 0.055 13.1 0.1 0.4 10.3 0.0 2.3 1 1 1 2 2 2 0 Translation initiation factor IF-2, N-terminal region DUF814 PF05670.8 EIE90136.1 - 5e-23 80.7 0.0 8.7e-23 80.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF814) DUF904 PF06005.7 EIE90136.1 - 0.18 12.1 4.6 0.43 10.9 1.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF904) VRR_NUC PF08774.6 EIE90137.1 - 0.036 14.0 0.0 0.06 13.3 0.0 1.4 1 0 0 1 1 1 0 VRR-NUC domain MAPEG PF01124.13 EIE90138.1 - 1.4e-21 76.4 1.0 1.7e-21 76.1 0.7 1.0 1 0 0 1 1 1 1 MAPEG family NAD_synthase PF02540.12 EIE90139.1 - 0.069 12.0 0.3 0.075 11.9 0.2 1.1 1 0 0 1 1 1 0 NAD synthase Homeobox PF00046.24 EIE90140.1 - 1.2e-15 56.9 0.8 1.9e-15 56.2 0.6 1.4 1 0 0 1 1 1 1 Homeobox domain HTH_23 PF13384.1 EIE90140.1 - 0.015 14.9 0.1 0.029 14.0 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain TetR_N PF00440.18 EIE90140.1 - 0.069 12.8 0.0 0.14 11.8 0.0 1.5 1 1 0 1 1 1 0 Bacterial regulatory proteins, tetR family Homeobox_KN PF05920.6 EIE90140.1 - 0.069 12.8 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 Homeobox KN domain DUF3350 PF11830.3 EIE90140.1 - 0.11 12.5 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3350) NOA36 PF06524.7 EIE90141.1 - 0.1 11.8 2.8 0.1 11.8 1.9 1.2 1 0 0 1 1 1 0 NOA36 protein Nop25 PF09805.4 EIE90142.1 - 0.075 13.1 21.4 0.35 10.9 8.5 2.4 2 1 1 3 3 3 0 Nucleolar protein 12 (25kDa) Vmethyltransf_C PF08456.5 EIE90142.1 - 0.86 8.9 8.5 1.1 8.6 5.9 1.1 1 0 0 1 1 1 0 Viral methyltransferase C-terminal Spore_coat_CotO PF14153.1 EIE90142.1 - 3.3 7.1 14.8 4.1 6.7 10.3 1.1 1 0 0 1 1 1 0 Spore coat protein CotO SWIB PF02201.13 EIE90144.1 - 0.066 12.8 0.2 1 9.0 0.0 2.4 2 0 0 2 2 2 0 SWIB/MDM2 domain RVT_1 PF00078.22 EIE90145.1 - 7.8e-24 84.2 0.1 1.3e-23 83.5 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CCDC92 PF14916.1 EIE90145.1 - 0.09 12.3 0.6 0.4 10.3 0.0 2.2 2 0 0 2 2 2 0 Coiled-coil domain of unknown function DDE_3 PF13358.1 EIE90147.1 - 0.0059 16.3 0.0 0.0081 15.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EIE90148.1 - 1.5e-18 66.9 0.0 1.8e-18 66.7 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE90148.1 - 0.0012 18.9 0.0 0.0016 18.5 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain PHP PF02811.14 EIE90149.1 - 0.086 12.6 0.9 0.19 11.4 0.3 1.8 2 0 0 2 2 2 0 PHP domain CCDC92 PF14916.1 EIE90150.1 - 0.0085 15.6 0.0 0.021 14.4 0.0 1.6 1 0 0 1 1 1 1 Coiled-coil domain of unknown function Rab5-bind PF09311.6 EIE90150.1 - 0.034 14.0 1.7 0.061 13.2 1.2 1.4 1 0 0 1 1 1 0 Rabaptin-like protein DivIC PF04977.10 EIE90150.1 - 0.055 12.9 2.5 0.1 12.1 1.7 1.4 1 0 0 1 1 1 0 Septum formation initiator Herpes_BLRF2 PF05812.7 EIE90150.1 - 0.081 12.7 0.1 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein DUF904 PF06005.7 EIE90150.1 - 0.14 12.4 1.1 0.29 11.4 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF904) RHINO PF15319.1 EIE90150.1 - 0.19 11.5 6.6 0.28 10.9 4.5 1.2 1 0 0 1 1 1 0 RAD9, RAD1, HUS1-interacting nuclear orphan protein Cep57_CLD_2 PF14197.1 EIE90150.1 - 0.32 10.9 3.6 0.2 11.5 1.0 1.8 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Lebercilin PF15619.1 EIE90150.1 - 2.5 7.5 6.1 0.26 10.6 1.3 1.5 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease HALZ PF02183.13 EIE90150.1 - 3.2 7.5 4.9 1.1 9.0 1.2 1.9 2 1 0 2 2 2 0 Homeobox associated leucine zipper HTH_Tnp_Tc5 PF03221.11 EIE90152.1 - 0.038 13.7 0.0 0.062 13.1 0.0 1.4 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain EF-hand_7 PF13499.1 EIE90152.1 - 0.12 12.4 0.0 0.33 11.1 0.0 1.8 1 1 0 1 1 1 0 EF-hand domain pair Myc_N PF01056.13 EIE90153.1 - 0.066 12.3 1.7 0.069 12.2 1.2 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Phage_integrase PF00589.17 EIE90154.1 - 0.00028 20.6 0.1 0.00037 20.1 0.1 1.3 1 0 0 1 1 1 1 Phage integrase family RVT_1 PF00078.22 EIE90155.1 - 8.2e-20 71.0 0.2 1.3e-19 70.4 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PseudoU_synth_1 PF01416.15 EIE90157.1 - 0.011 16.2 0.1 0.024 15.0 0.1 1.8 1 1 0 1 1 1 0 tRNA pseudouridine synthase PRP1_N PF06424.7 EIE90157.1 - 6.5 7.0 11.8 19 5.5 0.0 3.3 3 1 0 3 3 3 0 PRP1 splicing factor, N-terminal RRM_1 PF00076.17 EIE90158.1 - 0.088 12.4 1.7 0.75 9.4 0.0 3.2 4 0 0 4 4 4 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.18 EIE90158.1 - 0.46 10.5 2.7 1.3 9.1 0.2 2.2 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.1 EIE90158.1 - 2.7 7.7 9.3 0.55 9.9 0.5 2.9 3 0 0 3 3 3 0 Zinc knuckle RVT_1 PF00078.22 EIE90159.1 - 1.8e-35 122.2 0.1 5e-35 120.8 0.1 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.1 EIE90159.1 - 1.6e-05 25.1 0.8 6.1e-05 23.2 0.6 2.1 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Phage_int_SAM_1 PF02899.12 EIE90160.1 - 5.6e-05 23.2 0.1 0.0014 18.7 0.0 2.5 2 0 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.1 EIE90160.1 - 0.009 16.3 1.8 1.3 9.3 0.1 2.6 2 0 0 2 2 2 2 Phage integrase, N-terminal SAM-like domain DUF2501 PF10696.4 EIE90161.1 - 0.0062 16.4 0.1 0.0072 16.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2501) IL8 PF00048.15 EIE90161.1 - 0.039 13.9 0.0 0.051 13.5 0.0 1.3 1 1 0 1 1 1 0 Small cytokines (intecrine/chemokine), interleukin-8 like DDE_3 PF13358.1 EIE90162.1 - 0.0059 16.3 0.0 0.0081 15.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease RVT_1 PF00078.22 EIE90164.1 - 3.1e-13 49.5 0.0 5.2e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CCDC92 PF14916.1 EIE90164.1 - 0.069 12.7 0.6 0.34 10.5 0.0 2.3 2 0 0 2 2 2 0 Coiled-coil domain of unknown function Myc_N PF01056.13 EIE90165.1 - 0.066 12.3 1.7 0.069 12.2 1.2 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Phage_integrase PF00589.17 EIE90166.1 - 0.00028 20.6 0.1 0.00037 20.1 0.1 1.3 1 0 0 1 1 1 1 Phage integrase family RVT_1 PF00078.22 EIE90167.1 - 8.2e-20 71.0 0.2 1.3e-19 70.4 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PseudoU_synth_1 PF01416.15 EIE90169.1 - 0.011 16.1 0.1 0.024 15.0 0.1 1.8 1 1 0 1 1 1 0 tRNA pseudouridine synthase PRP1_N PF06424.7 EIE90169.1 - 0.39 11.0 12.4 0.77 10.0 0.1 3.3 3 1 0 3 3 3 0 PRP1 splicing factor, N-terminal Phage_int_SAM_1 PF02899.12 EIE90170.1 - 5.6e-05 23.2 0.1 0.0014 18.7 0.0 2.5 2 0 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.1 EIE90170.1 - 0.009 16.3 1.8 1.3 9.3 0.1 2.6 2 0 0 2 2 2 2 Phage integrase, N-terminal SAM-like domain Myosin_head PF00063.16 EIE90171.1 - 5.1e-249 827.9 0.7 9.1e-249 827.1 0.5 1.4 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.14 EIE90171.1 - 3.3e-31 107.2 4.8 3.3e-31 107.2 3.4 2.9 4 0 0 4 4 4 1 DIL domain IQ PF00612.22 EIE90171.1 - 2.3e-09 36.0 40.7 0.00024 20.4 2.0 6.5 7 0 0 7 7 7 4 IQ calmodulin-binding motif AAA_22 PF13401.1 EIE90171.1 - 0.005 16.9 0.0 0.051 13.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain CbiA PF01656.18 EIE90171.1 - 0.0084 15.5 0.1 0.024 14.0 0.1 1.8 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_19 PF13245.1 EIE90171.1 - 0.026 14.2 0.0 0.067 12.9 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_16 PF13191.1 EIE90171.1 - 0.027 14.4 0.0 0.027 14.4 0.0 3.3 3 1 0 3 3 3 0 AAA ATPase domain Reo_sigmaC PF04582.7 EIE90171.1 - 0.21 10.7 1.0 0.36 9.9 0.7 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein ABC_tran PF00005.22 EIE90171.1 - 0.3 11.3 0.0 0.3 11.3 0.0 3.4 3 1 0 3 3 3 0 ABC transporter WW PF00397.21 EIE90172.1 - 3.8e-05 23.4 1.9 9.6e-05 22.1 1.3 1.8 1 0 0 1 1 1 1 WW domain GRP PF07172.6 EIE90172.1 - 0.00035 20.9 13.9 0.00035 20.9 9.7 2.3 2 0 0 2 2 2 1 Glycine rich protein family DUF3824 PF12868.2 EIE90172.1 - 0.095 13.6 0.3 0.095 13.6 0.2 4.6 1 1 3 4 4 4 0 Domain of unknwon function (DUF3824) WD40 PF00400.27 EIE90174.1 - 8.8e-17 60.2 19.4 0.0027 17.5 0.0 7.0 8 0 0 8 8 8 6 WD domain, G-beta repeat PUF PF00806.14 EIE90175.1 - 9.4e-22 75.2 0.2 0.00049 19.4 0.0 7.2 7 0 0 7 7 7 5 Pumilio-family RNA binding repeat Cation_efflux PF01545.16 EIE90177.1 - 1.7e-23 83.1 0.6 2.9e-23 82.3 0.4 1.3 1 0 0 1 1 1 1 Cation efflux family MFS_1 PF07690.11 EIE90178.1 - 5.4e-10 38.5 10.7 3.6e-08 32.5 0.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Hum_adeno_E3A PF05393.6 EIE90178.1 - 0.094 12.3 1.1 0.9 9.2 0.1 2.3 2 0 0 2 2 2 0 Human adenovirus early E3A glycoprotein Methyltransf_11 PF08241.7 EIE90183.1 - 4.2e-08 33.5 0.0 7.9e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIE90183.1 - 0.00017 21.9 0.0 0.00048 20.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIE90183.1 - 0.00041 20.0 0.1 0.00061 19.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIE90183.1 - 0.00048 20.5 0.0 0.0016 18.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIE90183.1 - 0.00049 19.2 0.0 0.00067 18.8 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.10 EIE90183.1 - 0.019 14.6 0.0 0.024 14.2 0.0 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase TPMT PF05724.6 EIE90183.1 - 0.026 13.9 0.0 0.03 13.7 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Myb_DNA-bind_6 PF13921.1 EIE90184.1 - 7.2e-05 22.8 0.3 0.00011 22.2 0.2 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Spot_14 PF07084.7 EIE90186.1 - 0.066 13.0 0.0 0.071 12.9 0.0 1.1 1 0 0 1 1 1 0 Thyroid hormone-inducible hepatic protein Spot 14 Prenylcys_lyase PF07156.9 EIE90188.1 - 0.0046 15.8 0.1 0.0046 15.8 0.1 1.0 1 0 0 1 1 1 1 Prenylcysteine lyase WRW PF10206.4 EIE90188.1 - 0.079 13.0 0.5 0.15 12.1 0.4 1.5 1 1 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f Phage_term_sma PF07141.6 EIE90189.1 - 0.073 12.6 1.8 0.09 12.3 1.2 1.1 1 0 0 1 1 1 0 Putative bacteriophage terminase small subunit YxiJ PF14176.1 EIE90189.1 - 0.095 12.8 0.2 0.13 12.3 0.2 1.3 1 0 0 1 1 1 0 YxiJ-like protein Kinase-like PF14531.1 EIE90192.1 - 0.039 12.9 0.1 0.055 12.4 0.1 1.2 1 0 0 1 1 1 0 Kinase-like DUF3546 PF12066.3 EIE90195.1 - 0.0072 16.3 0.8 0.025 14.6 0.4 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3546) HTH_Tnp_Tc5 PF03221.11 EIE90195.1 - 0.056 13.2 0.0 0.24 11.2 0.0 2.1 2 0 0 2 2 2 0 Tc5 transposase DNA-binding domain GSHPx PF00255.14 EIE90196.1 - 6.6e-45 150.9 0.1 8.2e-45 150.6 0.1 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 EIE90196.1 - 4.2e-08 32.9 0.4 3.7e-07 29.8 0.3 2.0 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EIE90196.1 - 1.2e-06 28.1 0.1 3.7e-06 26.5 0.1 1.7 1 1 0 1 1 1 1 Redoxin SCO1-SenC PF02630.9 EIE90196.1 - 0.0031 17.1 0.1 0.26 10.8 0.0 2.4 2 1 0 2 2 2 1 SCO1/SenC YtfJ_HI0045 PF09695.5 EIE90196.1 - 0.035 13.4 0.1 0.12 11.6 0.0 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (YtfJ_HI0045) DUF4174 PF13778.1 EIE90196.1 - 0.085 12.9 0.0 0.27 11.3 0.0 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4174) GCR1_C PF12550.3 EIE90197.1 - 5.6e-26 90.2 0.6 5.7e-25 86.9 0.2 2.6 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes Vps53_N PF04100.7 EIE90199.1 - 8.9e-07 28.0 0.2 2.2e-06 26.7 0.1 1.7 2 0 0 2 2 2 1 Vps53-like, N-terminal COG7 PF10191.4 EIE90199.1 - 0.033 12.1 0.3 0.06 11.2 0.2 1.4 1 0 0 1 1 1 0 Golgi complex component 7 (COG7) DUF2529 PF10740.4 EIE90199.1 - 0.035 13.5 0.0 0.076 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2529) Ribosomal_L30 PF00327.15 EIE90200.1 - 4.5e-19 67.7 0.9 9.5e-19 66.7 0.6 1.6 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.7 EIE90200.1 - 9e-18 64.0 19.2 3.2e-17 62.2 13.3 2.0 1 1 0 1 1 1 1 Ribosomal L30 N-terminal domain CTP_transf_2 PF01467.21 EIE90201.1 - 1.7e-09 37.9 0.1 3.6e-09 36.8 0.0 1.6 2 0 0 2 2 2 1 Cytidylyltransferase FAD_syn PF06574.7 EIE90201.1 - 0.073 12.7 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 FAD synthetase NmrA PF05368.8 EIE90202.1 - 0.045 13.0 0.0 0.12 11.6 0.0 1.7 2 0 0 2 2 2 0 NmrA-like family RdRP PF05183.7 EIE90203.1 - 1.8e-98 330.7 0.1 5.5e-97 325.8 0.0 2.1 2 0 0 2 2 2 2 RNA dependent RNA polymerase Inhibitor_I53 PF11714.3 EIE90203.1 - 0.71 9.8 3.2 0.77 9.7 0.4 2.3 3 0 0 3 3 3 0 Thrombin inhibitor Madanin UQ_con PF00179.21 EIE90204.1 - 0.0013 18.1 0.0 0.0014 18.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme AAA PF00004.24 EIE90206.1 - 3.3e-13 49.9 0.0 8.2e-13 48.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 EIE90206.1 - 1.6e-12 46.8 0.6 2.1e-05 23.4 0.0 3.3 3 0 0 3 3 3 3 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 EIE90206.1 - 4.9e-08 33.1 0.1 2.7e-07 30.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EIE90206.1 - 9.4e-06 25.3 0.0 2.4e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EIE90206.1 - 1.3e-05 25.0 0.1 5.2e-05 23.1 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_18 PF13238.1 EIE90206.1 - 7.8e-05 22.9 0.2 0.00075 19.7 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_19 PF13245.1 EIE90206.1 - 0.00021 20.9 0.0 0.00064 19.4 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EIE90206.1 - 0.00028 21.7 0.1 0.0024 18.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EIE90206.1 - 0.00029 19.9 0.0 0.00077 18.5 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Zeta_toxin PF06414.7 EIE90206.1 - 0.00096 18.2 0.0 0.0023 17.0 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_25 PF13481.1 EIE90206.1 - 0.0012 18.2 0.1 0.3 10.4 0.0 2.6 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EIE90206.1 - 0.0035 16.7 0.0 0.029 13.7 0.0 2.3 1 1 0 1 1 1 1 IstB-like ATP binding protein APS_kinase PF01583.15 EIE90206.1 - 0.0088 15.7 0.0 0.021 14.4 0.0 1.7 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.1 EIE90206.1 - 0.016 15.1 0.5 0.051 13.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EIE90206.1 - 0.019 14.9 0.1 0.092 12.7 0.0 2.2 2 1 0 2 2 1 0 AAA ATPase domain RNA_helicase PF00910.17 EIE90206.1 - 0.02 15.0 2.4 0.1 12.7 0.1 3.4 3 1 0 3 3 3 0 RNA helicase AAA_30 PF13604.1 EIE90206.1 - 0.021 14.4 0.0 0.045 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EIE90206.1 - 0.023 14.4 0.5 1.1 8.9 0.0 2.6 1 1 1 2 2 2 0 NTPase AAA_28 PF13521.1 EIE90206.1 - 0.031 14.2 0.9 0.5 10.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EIE90206.1 - 0.22 11.8 0.1 0.22 11.8 0.0 3.5 2 2 1 3 3 3 0 AAA domain Pro_isomerase PF00160.16 EIE90208.1 - 4.2e-49 166.7 0.1 9.2e-49 165.6 0.1 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 EIE90208.1 - 3.9e-07 29.7 3.3 0.0039 17.0 0.1 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat Fungal_trans PF04082.13 EIE90209.1 - 7.2e-07 28.3 0.0 2.6e-06 26.4 0.0 1.8 1 1 1 2 2 2 1 Fungal specific transcription factor domain Peptidase_C14 PF00656.17 EIE90210.1 - 5.3e-61 206.4 0.0 6.2e-61 206.2 0.0 1.0 1 0 0 1 1 1 1 Caspase domain B PF02216.11 EIE90210.1 - 0.074 12.8 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 B domain Snf7 PF03357.16 EIE90211.1 - 5.8e-35 120.1 13.5 7e-35 119.9 9.4 1.0 1 0 0 1 1 1 1 Snf7 DUF3879 PF12995.2 EIE90211.1 - 0.02 14.5 0.4 0.025 14.1 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3879) Resolvase PF00239.16 EIE90211.1 - 0.068 13.0 2.7 0.086 12.7 1.6 1.4 1 1 0 1 1 1 0 Resolvase, N terminal domain DUF3418 PF11898.3 EIE90211.1 - 0.072 11.4 1.3 0.17 10.2 0.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3418) Glyco_hydro_17 PF00332.13 EIE90211.1 - 0.1 11.5 0.1 0.14 11.1 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 17 DUF4208 PF13907.1 EIE90211.1 - 0.22 11.7 2.2 8.2 6.7 0.1 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4208) Hydrolase PF00702.21 EIE90212.1 - 6.6e-17 62.6 0.0 1.9e-16 61.1 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EIE90212.1 - 6.3e-12 46.0 0.5 1.8e-11 44.5 0.4 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EIE90212.1 - 1.6e-09 37.1 0.3 3.9e-09 35.8 0.2 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 EIE90212.1 - 3.3e-06 26.9 0.1 2.1e-05 24.3 0.0 2.2 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EIE90212.1 - 8.5e-06 25.5 0.3 4.5e-05 23.1 0.0 2.3 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Glyco_tran_WecB PF03808.8 EIE90212.1 - 0.11 11.9 0.0 0.39 10.1 0.0 2.0 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family HECT PF00632.20 EIE90214.1 - 6e-51 173.4 0.2 7.2e-51 173.2 0.1 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Peptidase_C78 PF07910.8 EIE90215.1 - 1.2e-56 191.3 0.3 1.6e-56 190.9 0.2 1.1 1 0 0 1 1 1 1 Peptidase family C78 Myc_N PF01056.13 EIE90215.1 - 0.0035 16.5 6.0 0.0064 15.7 4.1 1.3 1 0 0 1 1 1 1 Myc amino-terminal region Pex16 PF08610.5 EIE90215.1 - 0.042 12.8 0.5 0.11 11.4 0.1 1.7 2 0 0 2 2 2 0 Peroxisomal membrane protein (Pex16) CDC45 PF02724.9 EIE90215.1 - 0.046 11.7 1.6 0.061 11.3 1.1 1.1 1 0 0 1 1 1 0 CDC45-like protein RXT2_N PF08595.6 EIE90215.1 - 0.33 10.7 6.0 0.072 12.8 1.7 1.7 2 0 0 2 2 2 0 RXT2-like, N-terminal CAF1A PF12253.3 EIE90215.1 - 1.3 9.1 13.7 3.6 7.7 9.5 1.7 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A NOA36 PF06524.7 EIE90215.1 - 1.8 7.7 5.9 3 7.0 4.1 1.2 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.5 EIE90215.1 - 3.4 7.9 19.2 3.7 7.8 12.2 1.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Thiolase_C PF02803.13 EIE90217.1 - 8.2e-11 41.4 0.2 8.5e-11 41.3 0.1 1.0 1 0 0 1 1 1 1 Thiolase, C-terminal domain DUF2620 PF10941.3 EIE90217.1 - 0.013 15.5 0.5 0.013 15.5 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF2620 Phospholip_A2_1 PF00068.14 EIE90218.1 - 0.048 13.8 9.9 0.37 11.0 0.4 2.1 2 0 0 2 2 2 0 Phospholipase A2 ET PF01684.11 EIE90218.1 - 6.8 6.8 14.2 5.4 7.1 1.5 2.5 2 0 0 2 2 2 0 ET module UDPGT PF00201.13 EIE90219.1 - 1.4e-30 106.2 0.0 1.8e-30 105.9 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 EIE90219.1 - 1.7e-06 27.7 0.0 2.6e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 EIE90219.1 - 2.5e-05 23.6 0.0 5.5e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 1 tRNA_int_endo_N PF02778.9 EIE90219.1 - 0.061 12.8 0.0 0.47 10.0 0.0 2.4 2 0 0 2 2 2 0 tRNA intron endonuclease, N-terminal domain Glyco_trans_1_4 PF13692.1 EIE90219.1 - 0.11 12.5 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 EIE90219.1 - 0.13 11.6 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferases group 1 DUF1981 PF09324.5 EIE90220.1 - 0.065 12.7 0.0 1.4 8.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1981) UDPGT PF00201.13 EIE90221.1 - 8.8e-39 133.3 0.0 8.1e-38 130.2 0.0 2.0 1 1 1 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_trans_1_3 PF13528.1 EIE90221.1 - 5.6e-07 29.0 0.0 0.00014 21.1 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 1 Glyco_tran_28_C PF04101.11 EIE90221.1 - 4.5e-06 26.4 0.0 7.7e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Phospholip_A2_1 PF00068.14 EIE90222.1 - 0.048 13.8 9.9 0.37 11.0 0.4 2.1 2 0 0 2 2 2 0 Phospholipase A2 ET PF01684.11 EIE90222.1 - 6.8 6.8 14.2 5.4 7.1 1.5 2.5 2 0 0 2 2 2 0 ET module Thiolase_C PF02803.13 EIE90223.1 - 8.2e-11 41.4 0.2 8.5e-11 41.3 0.1 1.0 1 0 0 1 1 1 1 Thiolase, C-terminal domain DUF2620 PF10941.3 EIE90223.1 - 0.013 15.5 0.5 0.013 15.5 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF2620 Phospholip_A2_1 PF00068.14 EIE90224.1 - 0.048 13.8 9.9 0.37 11.0 0.4 2.1 2 0 0 2 2 2 0 Phospholipase A2 ET PF01684.11 EIE90224.1 - 6.8 6.8 14.2 5.4 7.1 1.5 2.5 2 0 0 2 2 2 0 ET module UDPGT PF00201.13 EIE90225.1 - 8.3e-35 120.2 0.0 1.1e-33 116.5 0.0 2.0 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_trans_1_3 PF13528.1 EIE90225.1 - 5.2e-11 42.2 0.0 0.00014 21.2 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 1 Glyco_tran_28_C PF04101.11 EIE90225.1 - 3.5e-06 26.7 0.0 6.2e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain NmrA PF05368.8 EIE90225.1 - 0.025 13.8 0.0 0.049 12.8 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family Serglycin PF04360.7 EIE90226.1 - 0.01 15.5 0.1 0.017 14.8 0.1 1.4 1 0 0 1 1 1 0 Serglycin DUF1620 PF07774.8 EIE90226.1 - 0.019 14.2 0.2 0.025 13.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1620) Pkinase PF00069.20 EIE90227.1 - 8.1e-74 248.0 0.0 1.1e-73 247.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE90227.1 - 2.8e-34 118.3 0.0 3.8e-34 117.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EIE90227.1 - 5.6e-12 45.9 4.4 1.6e-11 44.5 3.1 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EIE90227.1 - 2.4e-05 23.4 0.0 8.1e-05 21.7 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EIE90227.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 EIE90227.1 - 0.13 11.3 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family X8 PF07983.8 EIE90228.1 - 0.13 12.7 0.1 0.2 12.1 0.1 1.3 1 0 0 1 1 1 0 X8 domain DDE_3 PF13358.1 EIE90229.1 - 3.6e-14 52.7 0.1 4.9e-14 52.3 0.1 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease CreD PF06123.7 EIE90230.1 - 0.051 12.1 1.6 0.12 10.8 1.1 1.6 1 0 0 1 1 1 0 Inner membrane protein CreD NDUF_B12 PF08122.7 EIE90232.1 - 7.9e-20 70.3 0.6 9.1e-20 70.1 0.4 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family Thiolase_N PF00108.18 EIE90233.1 - 1.2e-101 339.1 0.9 1.8e-101 338.5 0.6 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EIE90233.1 - 6.6e-44 148.2 1.0 6.6e-44 148.2 0.7 2.0 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EIE90233.1 - 1.7e-05 24.4 0.4 1.7e-05 24.4 0.3 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 EIE90233.1 - 0.15 11.7 2.3 2.6 7.7 0.1 3.1 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III UDPGT PF00201.13 EIE90235.1 - 1.1e-35 123.1 0.0 5e-35 121.0 0.0 1.8 1 1 1 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_trans_1_3 PF13528.1 EIE90235.1 - 1.7e-05 24.2 0.0 0.00082 18.6 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 1 Glyco_tran_28_C PF04101.11 EIE90235.1 - 0.00074 19.2 0.0 0.0013 18.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glycos_transf_1 PF00534.15 EIE90235.1 - 0.016 14.5 0.0 0.034 13.5 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EIE90235.1 - 0.09 12.9 0.0 0.31 11.1 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferases group 1 tRNA_int_endo_N PF02778.9 EIE90235.1 - 0.12 11.9 0.0 1 8.9 0.0 2.3 2 0 0 2 2 2 0 tRNA intron endonuclease, N-terminal domain eIF3_subunit PF08597.5 EIE90236.1 - 1.2e-49 169.0 32.8 1.5e-49 168.8 22.7 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit IF-2B PF01008.12 EIE90236.1 - 0.12 11.2 0.1 0.12 11.2 0.1 1.7 2 0 0 2 2 2 0 Initiation factor 2 subunit family DUF2547 PF10818.3 EIE90236.1 - 0.73 10.5 2.7 21 5.8 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2547) CDC27 PF09507.5 EIE90236.1 - 7 5.7 25.6 12 5.0 13.6 2.1 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 AATF-Che1 PF13339.1 EIE90236.1 - 7 6.8 16.0 2.6 8.2 7.5 2.1 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor IncA PF04156.9 EIE90237.1 - 0.0011 18.6 8.8 0.0011 18.6 6.1 2.7 2 1 0 2 2 2 1 IncA protein TMF_TATA_bd PF12325.3 EIE90237.1 - 0.0012 18.5 6.2 0.0012 18.5 4.3 2.2 2 0 0 2 2 2 1 TATA element modulatory factor 1 TATA binding OmpH PF03938.9 EIE90237.1 - 0.0027 17.6 3.8 0.0027 17.6 2.6 1.8 2 1 0 2 2 2 1 Outer membrane protein (OmpH-like) CENP-Q PF13094.1 EIE90237.1 - 0.0054 16.7 8.4 0.0054 16.7 5.8 1.8 2 0 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit RTBV_P46 PF06216.6 EIE90237.1 - 0.017 13.9 3.6 0.035 12.9 2.5 1.4 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein TMCO5 PF14992.1 EIE90237.1 - 0.022 13.9 10.9 0.012 14.8 5.7 1.8 2 0 0 2 2 2 0 TMCO5 family Ribosomal_L13 PF00572.13 EIE90237.1 - 0.03 14.3 0.8 0.064 13.3 0.6 1.5 1 0 0 1 1 1 0 Ribosomal protein L13 TMPIT PF07851.8 EIE90237.1 - 0.06 12.4 6.1 0.83 8.6 2.1 2.4 2 0 0 2 2 2 0 TMPIT-like protein Tropomyosin_1 PF12718.2 EIE90237.1 - 0.079 12.8 14.8 0.078 12.8 7.3 2.3 2 0 0 2 2 2 0 Tropomyosin like ADIP PF11559.3 EIE90237.1 - 0.15 11.9 13.3 0.016 15.1 5.7 2.0 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF1515 PF07439.6 EIE90237.1 - 0.74 9.6 2.7 11 5.9 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1515) V_ATPase_I PF01496.14 EIE90237.1 - 0.83 7.4 5.1 1.2 6.9 3.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF812 PF05667.6 EIE90237.1 - 1.2 7.5 16.0 0.11 10.9 8.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF812) XhlA PF10779.4 EIE90237.1 - 2.4 8.1 5.1 5.2 7.0 3.6 1.6 1 0 0 1 1 1 0 Haemolysin XhlA bZIP_1 PF00170.16 EIE90237.1 - 4.1 7.4 17.7 0.23 11.4 4.3 3.2 3 1 0 3 3 3 0 bZIP transcription factor RVT_1 PF00078.22 EIE90238.1 - 5.5e-27 94.5 0.0 1.2e-26 93.4 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EIE90238.1 - 1e-17 63.8 2.8 2.4e-17 62.6 1.5 2.0 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EIE90238.1 - 1e-07 32.2 0.1 2.4e-07 30.9 0.1 1.7 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family UDPGT PF00201.13 EIE90240.1 - 5.1e-33 114.3 0.0 4.7e-32 111.1 0.0 2.0 1 1 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_trans_1_3 PF13528.1 EIE90240.1 - 9.8e-07 28.2 0.0 0.0032 16.7 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 1 Glyco_tran_28_C PF04101.11 EIE90240.1 - 0.00024 20.8 0.0 0.00049 19.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_hydro_20b PF02838.10 EIE90240.1 - 0.016 15.7 0.0 0.17 12.4 0.0 2.1 2 0 0 2 2 2 0 Glycosyl hydrolase family 20, domain 2 Glyco_trans_1_4 PF13692.1 EIE90240.1 - 0.041 14.0 0.0 0.22 11.6 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferases group 1 tRNA_int_endo_N PF02778.9 EIE90240.1 - 0.043 13.3 0.0 1 8.9 0.0 2.6 2 0 0 2 2 2 0 tRNA intron endonuclease, N-terminal domain UDPGT PF00201.13 EIE90241.1 - 1.1e-35 123.2 0.0 5.2e-35 120.9 0.0 1.9 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_trans_1_3 PF13528.1 EIE90241.1 - 5e-08 32.4 0.0 0.0052 16.0 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 1 Glyco_tran_28_C PF04101.11 EIE90241.1 - 1.3e-05 24.8 0.0 2.6e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glycos_transf_1 PF00534.15 EIE90241.1 - 0.018 14.4 0.0 0.046 13.1 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EIE90241.1 - 0.044 13.9 0.0 0.15 12.2 0.0 1.9 1 0 0 1 1 1 0 Glycosyl transferases group 1 tRNA_int_endo_N PF02778.9 EIE90241.1 - 0.047 13.2 0.0 1.1 8.8 0.0 2.6 2 0 0 2 2 2 0 tRNA intron endonuclease, N-terminal domain ET PF01684.11 EIE90242.1 - 1.9 8.6 13.3 4.7 7.3 1.4 2.5 2 0 0 2 2 2 0 ET module Toxin_19 PF08088.7 EIE90242.1 - 5.1 7.0 21.9 5.2 7.0 4.7 2.4 2 0 0 2 2 2 0 Conotoxin I-superfamily UDPGT PF00201.13 EIE90243.1 - 1.3e-26 93.2 0.1 6.3e-24 84.3 0.0 2.0 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_trans_1_3 PF13528.1 EIE90243.1 - 3.2e-05 23.2 0.0 7.8e-05 22.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 1 Glyco_tran_28_C PF04101.11 EIE90243.1 - 7.7e-05 22.4 0.0 0.00014 21.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glycos_transf_1 PF00534.15 EIE90243.1 - 0.00046 19.6 0.0 0.00068 19.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EIE90243.1 - 0.035 14.2 0.0 0.06 13.4 0.0 1.5 1 1 0 1 1 1 0 Glycosyl transferases group 1 tRNA_int_endo_N PF02778.9 EIE90243.1 - 0.082 12.4 1.2 0.42 10.1 0.0 2.4 3 0 0 3 3 3 0 tRNA intron endonuclease, N-terminal domain Metallophos PF00149.23 EIE90244.1 - 2.9e-29 101.9 0.0 3.1e-29 101.8 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase NOA36 PF06524.7 EIE90244.1 - 0.13 11.5 0.0 0.18 11.0 0.0 1.1 1 0 0 1 1 1 0 NOA36 protein GCR1_C PF12550.3 EIE90245.1 - 1.3e-22 79.3 0.5 1.3e-22 79.3 0.3 1.5 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes DUF3375 PF11855.3 EIE90245.1 - 0.0036 16.1 0.2 0.01 14.6 0.0 1.8 2 1 0 2 2 2 1 Protein of unknown function (DUF3375) OmpH PF03938.9 EIE90245.1 - 0.035 14.0 0.0 0.043 13.7 0.0 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF605 PF04652.11 EIE90245.1 - 6.3 6.0 11.6 7.7 5.7 8.0 1.1 1 0 0 1 1 1 0 Vta1 like C2 PF00168.25 EIE90247.1 - 1.9e-06 27.6 0.0 2.5e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 C2 domain Myosin_head PF00063.16 EIE90249.1 - 1.4e-247 823.2 3.6 1.4e-247 823.2 2.5 2.1 2 0 0 2 2 2 1 Myosin head (motor domain) DIL PF01843.14 EIE90249.1 - 2.1e-21 75.7 1.3 8.9e-21 73.7 0.5 2.5 2 0 0 2 2 2 1 DIL domain IQ PF00612.22 EIE90249.1 - 3.4e-13 47.9 25.3 4.9e-05 22.5 0.4 6.1 6 0 0 6 6 6 4 IQ calmodulin-binding motif AAA_22 PF13401.1 EIE90249.1 - 0.0031 17.6 0.6 0.027 14.6 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EIE90249.1 - 0.01 15.8 2.6 0.17 11.8 0.0 3.1 2 1 0 2 2 2 0 AAA ATPase domain AAA_10 PF12846.2 EIE90249.1 - 0.021 14.2 0.1 0.086 12.2 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain AAA_19 PF13245.1 EIE90249.1 - 0.091 12.5 0.0 0.27 11.0 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain ABC_tran PF00005.22 EIE90249.1 - 0.41 10.9 0.0 0.41 10.9 0.0 3.1 2 1 0 2 2 1 0 ABC transporter DUF2730 PF10805.3 EIE90249.1 - 1.5 8.5 13.0 0.089 12.5 0.4 3.9 2 1 2 4 4 4 0 Protein of unknown function (DUF2730) Retrotrans_gag PF03732.12 EIE90249.1 - 1.8 8.7 12.6 0.18 11.9 2.5 3.5 3 0 0 3 3 3 0 Retrotransposon gag protein IncA PF04156.9 EIE90249.1 - 8.2 5.9 27.3 4.6 6.7 9.6 2.5 1 1 1 2 2 2 0 IncA protein Med12 PF09497.5 EIE90250.1 - 3.1e-23 81.5 1.0 8.7e-23 80.0 0.1 2.4 2 0 0 2 2 2 1 Transcription mediator complex subunit Med12 Med12-LCEWAV PF12145.3 EIE90250.1 - 0.00062 18.3 2.5 0.00076 18.0 0.1 2.2 2 0 0 2 2 2 1 Eukaryotic Mediator 12 subunit domain zf-C2H2_4 PF13894.1 EIE90251.1 - 1.5e-06 28.1 4.2 0.0025 18.0 0.2 2.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EIE90251.1 - 7.5e-06 25.9 9.1 0.0015 18.7 0.4 2.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type INO80_Ies4 PF08193.6 EIE90251.1 - 7.7e-06 26.0 8.1 7.7e-06 26.0 5.6 1.7 2 0 0 2 2 2 1 INO80 complex subunit Ies4 Ribosomal_60s PF00428.14 EIE90251.1 - 0.041 14.2 1.4 0.1 13.0 1.0 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein zf-C2H2_6 PF13912.1 EIE90251.1 - 0.35 10.8 1.8 7.1 6.6 0.0 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EIE90251.1 - 8 6.9 10.2 1.9 8.9 0.1 3.0 3 0 0 3 3 3 0 Zinc-finger double domain LRR_8 PF13855.1 EIE90252.1 - 0.074 12.8 13.3 14 5.5 0.1 6.1 5 2 1 6 6 6 0 Leucine rich repeat JmjC PF02373.17 EIE90253.1 - 3.3e-40 136.8 1.3 1.5e-39 134.7 0.9 2.2 1 1 0 1 1 1 1 JmjC domain, hydroxylase zf-HC5HC2H PF13771.1 EIE90253.1 - 2e-18 66.2 8.5 5.9e-18 64.8 5.9 1.8 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 EIE90253.1 - 1.8e-17 63.2 8.7 3.9e-17 62.2 6.1 1.6 1 0 0 1 1 1 1 PHD-zinc-finger like domain JmjN PF02375.12 EIE90253.1 - 7.9e-09 34.8 0.6 1.7e-08 33.7 0.4 1.6 1 0 0 1 1 1 1 jmjN domain MDH PF02315.11 EIE90253.1 - 0.013 15.4 0.3 0.044 13.7 0.2 2.0 1 0 0 1 1 1 0 Methanol dehydrogenase beta subunit YajC PF02699.10 EIE90253.1 - 0.15 11.7 0.3 0.3 10.7 0.2 1.4 1 0 0 1 1 1 0 Preprotein translocase subunit DUF1779 PF08680.5 EIE90253.1 - 0.21 11.4 1.2 0.28 11.0 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1779) MIR PF02815.14 EIE90254.1 - 3.2e-15 56.1 0.4 9.4e-14 51.3 0.0 2.0 1 1 1 2 2 2 2 MIR domain Ins145_P3_rec PF08709.6 EIE90254.1 - 0.0028 16.7 0.1 0.0089 15.0 0.0 1.7 2 0 0 2 2 2 1 Inositol 1,4,5-trisphosphate/ryanodine receptor DUF1700 PF08006.6 EIE90255.1 - 0.077 12.2 3.3 0.94 8.7 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) Cnd2 PF05786.9 EIE90256.1 - 7.9e-104 348.6 36.8 1.6e-76 258.3 9.4 3.0 1 1 1 2 2 2 2 Condensin complex subunit 2 Sulfate_transp PF00916.15 EIE90257.1 - 3.9e-74 249.1 10.1 7.3e-74 248.2 7.0 1.5 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EIE90257.1 - 1.3e-33 114.4 2.2 1.3e-33 114.4 1.5 4.0 4 0 0 4 4 4 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EIE90257.1 - 3.6e-11 42.5 0.0 6.6e-11 41.6 0.0 1.3 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 EIE90257.1 - 0.00057 19.8 0.1 0.0013 18.7 0.1 1.6 1 0 0 1 1 1 1 STAS domain Cpn60_TCP1 PF00118.19 EIE90258.1 - 1e-145 486.1 13.0 1.2e-145 485.9 9.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family RNA_pol_Rpb2_6 PF00562.23 EIE90258.1 - 0.057 12.1 0.1 0.077 11.7 0.1 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 6 PcfK PF14058.1 EIE90258.1 - 0.13 12.4 0.2 0.24 11.5 0.2 1.4 1 0 0 1 1 1 0 PcfK-like protein adh_short PF00106.20 EIE90259.1 - 2e-27 96.1 0.2 2.2e-27 95.9 0.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIE90259.1 - 6e-12 45.5 0.1 6.7e-12 45.4 0.1 1.0 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EIE90259.1 - 4.7e-09 36.3 0.1 5.5e-09 36.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 EIE90259.1 - 0.00014 20.9 0.1 0.00014 20.8 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EIE90259.1 - 0.00033 20.7 1.2 0.00071 19.6 0.8 1.6 1 1 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EIE90259.1 - 0.00042 20.0 0.1 0.00093 18.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_4 PF07993.7 EIE90259.1 - 0.00082 18.3 0.1 0.0013 17.7 0.1 1.3 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 EIE90259.1 - 0.00097 18.4 0.4 0.0012 18.0 0.3 1.1 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EIE90259.1 - 0.0025 17.2 0.1 0.003 17.0 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 EIE90259.1 - 0.0035 17.3 0.2 0.0063 16.5 0.2 1.4 1 0 0 1 1 1 1 TrkA-N domain Methyltransf_18 PF12847.2 EIE90259.1 - 0.0065 17.0 0.1 0.011 16.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Zeta_toxin PF06414.7 EIE90259.1 - 0.009 15.1 0.1 0.011 14.8 0.0 1.2 1 1 0 1 1 1 1 Zeta toxin Methyltransf_25 PF13649.1 EIE90259.1 - 0.01 16.1 0.0 0.27 11.6 0.0 2.0 1 1 1 2 2 2 0 Methyltransferase domain DUF1776 PF08643.5 EIE90259.1 - 0.033 13.3 0.0 0.058 12.5 0.0 1.2 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) HTH_Tnp_Tc3_2 PF01498.13 EIE90260.1 - 4.4e-06 26.6 1.6 8.9e-06 25.6 0.2 2.0 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.1 EIE90261.1 - 1.3e-17 63.9 0.0 2.3e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE90261.1 - 2.6e-08 33.8 2.9 3.1e-08 33.5 0.3 2.2 1 1 1 2 2 2 1 Transposase HTH_29 PF13551.1 EIE90261.1 - 0.071 13.2 1.2 0.23 11.6 0.8 1.9 1 1 0 1 1 1 0 Winged helix-turn helix HTH_12 PF08461.5 EIE90261.1 - 0.11 12.2 0.1 0.34 10.6 0.0 1.8 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain NFRKB_winged PF14465.1 EIE90261.1 - 0.12 12.1 2.5 2.1 8.2 0.4 2.7 2 1 0 2 2 2 0 NFRKB Winged Helix-like HTH_32 PF13565.1 EIE90261.1 - 0.56 11.0 5.2 0.27 12.0 0.6 2.6 4 0 0 4 4 4 0 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.1 EIE90261.1 - 1.7 7.8 3.8 1.1 8.5 0.1 2.4 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 HTH_Tnp_Tc3_2 PF01498.13 EIE90265.1 - 4.1e-05 23.5 2.6 8e-05 22.6 0.5 2.1 1 1 2 3 3 3 1 Transposase HTH_23 PF13384.1 EIE90265.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain DDE_Tnp_IS1595 PF12762.2 EIE90266.1 - 8.8e-09 35.3 0.0 1.8e-08 34.3 0.0 1.5 1 1 0 1 1 1 1 ISXO2-like transposase domain DDE_3 PF13358.1 EIE90267.1 - 0.0013 18.5 0.0 0.0013 18.4 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE90268.1 - 2e-06 27.7 0.4 2e-06 27.7 0.3 1.9 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.1 EIE90269.1 - 4e-17 62.3 0.1 6.6e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE90269.1 - 1.7e-07 31.1 0.6 9.2e-07 28.8 0.1 2.3 2 0 0 2 2 2 1 Transposase GTP_EFTU_D2 PF03144.20 EIE90269.1 - 0.022 14.8 0.1 0.12 12.4 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu domain 2 DDE_3 PF13358.1 EIE90270.1 - 4.4e-21 75.1 0.4 6e-21 74.7 0.3 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_IS1595 PF12762.2 EIE90272.1 - 6.3e-19 68.3 0.0 9e-19 67.8 0.0 1.2 1 0 0 1 1 1 1 ISXO2-like transposase domain HTH_Tnp_ISL3 PF13542.1 EIE90273.1 - 2.5e-05 23.3 0.3 3.1e-05 23.0 0.2 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_28 PF13518.1 EIE90273.1 - 5.5e-05 23.0 0.0 6.8e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.1 EIE90273.1 - 7.1e-05 22.3 0.1 8.1e-05 22.1 0.1 1.1 1 0 0 1 1 1 1 Homeodomain-like domain HTH_11 PF08279.7 EIE90273.1 - 0.011 15.3 0.1 0.013 15.1 0.1 1.2 1 0 0 1 1 1 0 HTH domain HTH_DeoR PF08220.7 EIE90273.1 - 0.015 14.8 0.1 0.018 14.5 0.1 1.1 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain Sigma70_r4_2 PF08281.7 EIE90273.1 - 0.016 14.6 0.0 0.019 14.4 0.0 1.2 1 0 0 1 1 1 0 Sigma-70, region 4 GerE PF00196.14 EIE90273.1 - 0.032 13.5 0.0 0.039 13.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family HTH_AsnC-type PF13404.1 EIE90273.1 - 0.058 12.9 0.1 0.081 12.4 0.0 1.3 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain MerR PF00376.18 EIE90273.1 - 0.066 12.7 0.3 0.1 12.1 0.2 1.4 1 0 0 1 1 1 0 MerR family regulatory protein HTH_38 PF13936.1 EIE90273.1 - 0.072 12.6 0.0 0.081 12.4 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_1 PF01527.15 EIE90273.1 - 0.11 12.4 0.0 0.13 12.2 0.0 1.1 1 0 0 1 1 1 0 Transposase HTH_29 PF13551.1 EIE90273.1 - 0.11 12.6 0.0 0.12 12.5 0.0 1.1 1 0 0 1 1 1 0 Winged helix-turn helix HTH_30 PF13556.1 EIE90273.1 - 0.14 11.7 0.1 0.17 11.4 0.0 1.1 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain Transposase_21 PF02992.9 EIE90275.1 - 3.9e-22 78.4 0.1 3.9e-22 78.4 0.1 1.8 3 0 0 3 3 3 1 Transposase family tnp2 DDE_3 PF13358.1 EIE90276.1 - 9.5e-11 41.6 0.2 1.7e-10 40.8 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF3226 PF11536.3 EIE90276.1 - 0.0073 15.7 0.0 0.01 15.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3226) HTH_IclR PF09339.5 EIE90277.1 - 7.9e-05 22.1 0.1 0.00014 21.3 0.0 1.5 2 0 0 2 2 1 1 IclR helix-turn-helix domain HTH_23 PF13384.1 EIE90277.1 - 0.0001 21.7 0.0 0.00017 21.0 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_11 PF08279.7 EIE90277.1 - 0.00026 20.5 0.0 0.00043 19.8 0.0 1.3 1 0 0 1 1 1 1 HTH domain HTH_7 PF02796.10 EIE90277.1 - 0.0019 18.0 0.1 0.051 13.4 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase Sigma70_r4_2 PF08281.7 EIE90277.1 - 0.0021 17.4 0.0 0.0033 16.8 0.0 1.3 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_AsnC-type PF13404.1 EIE90277.1 - 0.0025 17.2 0.0 0.0039 16.6 0.0 1.3 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_17 PF12728.2 EIE90277.1 - 0.0039 17.3 0.0 0.0049 17.0 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4 PF04545.11 EIE90277.1 - 0.0048 16.1 0.0 0.0088 15.3 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_36 PF13730.1 EIE90277.1 - 0.0067 16.5 0.0 0.0092 16.0 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain GerE PF00196.14 EIE90277.1 - 0.0074 15.5 0.0 0.012 14.8 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_38 PF13936.1 EIE90277.1 - 0.0089 15.5 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain UPF0122 PF04297.9 EIE90277.1 - 0.0089 16.0 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 Putative helix-turn-helix protein, YlxM / p13 like HTH_24 PF13412.1 EIE90277.1 - 0.0099 15.2 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.2 EIE90277.1 - 0.011 15.3 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 MarR family Terminase_5 PF06056.7 EIE90277.1 - 0.012 15.0 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) HTH_29 PF13551.1 EIE90277.1 - 0.016 15.3 0.0 0.02 15.0 0.0 1.2 1 0 0 1 1 1 0 Winged helix-turn helix HTH_Tnp_4 PF13613.1 EIE90277.1 - 0.023 14.2 0.0 0.035 13.6 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_6 PF01418.12 EIE90277.1 - 0.025 14.3 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family HTH_22 PF13309.1 EIE90277.1 - 0.029 14.1 0.0 0.062 13.0 0.0 1.5 1 0 0 1 1 1 0 HTH domain DUF603 PF04645.7 EIE90277.1 - 0.042 13.8 0.0 0.042 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF603 HTH_31 PF13560.1 EIE90277.1 - 0.049 13.8 0.0 0.061 13.5 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain KfrA_N PF11740.3 EIE90277.1 - 0.055 13.9 0.0 0.062 13.7 0.0 1.1 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term DUF134 PF02001.11 EIE90277.1 - 0.058 13.3 0.0 0.082 12.8 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function DUF134 HTH_Crp_2 PF13545.1 EIE90277.1 - 0.06 13.1 0.0 0.079 12.7 0.0 1.3 1 1 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_28 PF13518.1 EIE90277.1 - 0.081 12.9 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_20 PF12840.2 EIE90277.1 - 0.091 12.5 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_ECF PF07638.6 EIE90277.1 - 0.12 12.0 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 ECF sigma factor TetR_N PF00440.18 EIE90277.1 - 0.13 11.9 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family HTH_Mga PF08280.6 EIE90277.1 - 0.14 11.9 0.1 0.3 10.8 0.0 1.5 2 0 0 2 2 2 0 M protein trans-acting positive regulator (MGA) HTH domain DDE_3 PF13358.1 EIE90278.1 - 6.9e-08 32.3 0.0 9.7e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_7 PF02796.10 EIE90278.1 - 0.0016 18.2 0.1 0.0043 16.8 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_23 PF13384.1 EIE90278.1 - 0.14 11.8 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain Transposase_21 PF02992.9 EIE90280.1 - 1.7e-17 63.2 0.1 2e-17 63.0 0.1 1.1 1 0 0 1 1 1 1 Transposase family tnp2 DUF1258 PF06869.7 EIE90280.1 - 0.042 12.9 0.0 0.06 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1258) DDE_3 PF13358.1 EIE90281.1 - 4.2e-18 65.4 0.0 1.1e-17 64.1 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE90281.1 - 2.3e-07 30.7 0.4 9e-07 28.8 0.4 2.0 2 1 0 2 2 2 1 Transposase Peptidase_S55 PF05580.7 EIE90281.1 - 0.069 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 SpoIVB peptidase S55 rve PF00665.21 EIE90284.1 - 8.1e-23 80.8 0.0 9.7e-22 77.3 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 EIE90284.1 - 9.1e-17 61.1 0.0 1.8e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 EIE90284.1 - 2.3e-06 27.9 0.0 1.3e-05 25.6 0.0 2.4 2 0 0 2 2 2 1 Aspartyl protease UBN2_2 PF14227.1 EIE90284.1 - 2e-05 24.1 0.7 0.00072 19.1 0.1 3.6 4 1 0 4 4 4 1 gag-polypeptide of LTR copia-type Retrotrans_gag PF03732.12 EIE90284.1 - 2.7e-05 24.1 1.1 0.0001 22.2 0.0 2.4 2 0 0 2 2 2 1 Retrotransposon gag protein gag-asp_proteas PF13975.1 EIE90284.1 - 0.0009 19.0 0.0 0.0019 17.9 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease UBN2 PF14223.1 EIE90284.1 - 0.0054 16.5 0.7 0.22 11.2 0.1 2.8 3 0 0 3 3 3 1 gag-polypeptide of LTR copia-type zf-H2C2 PF09337.5 EIE90284.1 - 0.0072 15.7 0.1 0.025 14.0 0.0 2.0 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Rep_4 PF05797.6 EIE90288.1 - 0.15 10.7 0.8 0.49 9.0 0.1 1.8 1 1 1 2 2 2 0 Yeast trans-acting factor (REP1/REP2) Retrotrans_gag PF03732.12 EIE90289.1 - 0.0031 17.5 0.3 0.011 15.8 0.1 1.9 2 0 0 2 2 2 1 Retrotransposon gag protein DUF2443 PF10398.4 EIE90289.1 - 0.092 12.5 0.3 0.19 11.5 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) HTH_Tnp_Tc3_2 PF01498.13 EIE90290.1 - 1e-14 54.3 1.1 1.7e-14 53.5 0.7 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.1 EIE90290.1 - 0.0023 17.6 0.1 0.0047 16.6 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE90291.1 - 0.067 13.2 1.2 0.3 11.1 0.0 2.8 4 0 0 4 4 4 0 Transposase HTH_29 PF13551.1 EIE90291.1 - 0.083 13.0 0.1 0.19 11.8 0.1 1.6 1 0 0 1 1 1 0 Winged helix-turn helix DDE_3 PF13358.1 EIE90292.1 - 0.00057 19.6 0.3 0.00083 19.1 0.2 1.6 1 1 0 1 1 1 1 DDE superfamily endonuclease PRMT5 PF05185.11 EIE90296.1 - 9.4e-169 562.0 0.4 1.2e-168 561.7 0.3 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Met_10 PF02475.11 EIE90296.1 - 0.014 15.0 0.0 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein DUF2392 PF10288.4 EIE90298.1 - 2.9e-24 85.4 0.0 5.9e-24 84.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) Alginate_lyase PF05426.7 EIE90299.1 - 4e-16 59.1 0.1 7.7e-13 48.4 0.0 2.3 2 0 0 2 2 2 2 Alginate lyase O-ag_pol_Wzy PF14296.1 EIE90299.1 - 0.14 10.7 0.1 2.8 6.4 0.0 2.1 2 0 0 2 2 2 0 O-antigen polysaccharide polymerase Wzy CP2 PF04516.10 EIE90301.1 - 3.3e-20 72.1 0.1 3.7e-20 71.9 0.1 1.0 1 0 0 1 1 1 1 CP2 transcription factor Lactamase_B_2 PF12706.2 EIE90302.1 - 3e-22 79.1 0.1 6.4e-22 78.0 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EIE90302.1 - 2.4e-09 37.1 0.0 5.3e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.1 EIE90302.1 - 3.8e-07 29.4 0.0 7.4e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 tRNase Z endonuclease HSP70 PF00012.15 EIE90303.1 - 9.9e-265 879.1 10.0 1.1e-264 878.9 6.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EIE90303.1 - 1.9e-14 52.9 3.6 9.4e-12 44.1 0.6 2.6 2 1 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.1 EIE90303.1 - 7.7e-05 22.5 3.7 0.6 9.9 0.0 4.3 3 1 1 4 4 4 3 Cell division protein FtsA FGGY_C PF02782.11 EIE90303.1 - 0.0002 21.0 0.0 0.00042 19.9 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DbpA PF03880.10 EIE90303.1 - 0.13 11.9 0.7 16 5.2 0.0 3.2 3 0 0 3 3 3 0 DbpA RNA binding domain DUF603 PF04645.7 EIE90303.1 - 0.14 12.1 3.5 0.57 10.0 1.9 2.2 2 1 0 2 2 2 0 Protein of unknown function, DUF603 Effector_1 PF04518.7 EIE90303.1 - 0.16 10.9 3.0 0.31 9.9 2.1 1.4 1 0 0 1 1 1 0 Effector from type III secretion system Hydantoinase_A PF01968.13 EIE90303.1 - 0.27 10.2 6.4 0.081 12.0 0.3 2.7 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase Glyco_hydro_28 PF00295.12 EIE90304.1 - 7.2e-66 222.3 28.7 9.3e-66 222.0 19.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 TSLP PF15216.1 EIE90304.1 - 0.0054 16.4 1.9 0.014 15.1 1.3 1.6 1 0 0 1 1 1 1 Thymic stromal lymphopoietin HEAT_2 PF13646.1 EIE90305.1 - 1.3e-13 51.0 8.1 0.0066 16.7 0.0 7.0 5 2 0 6 6 6 4 HEAT repeats HEAT PF02985.17 EIE90305.1 - 2e-09 36.7 18.0 0.28 11.3 0.0 8.9 10 0 0 10 10 10 4 HEAT repeat HEAT_EZ PF13513.1 EIE90305.1 - 4.4e-05 23.8 11.4 0.022 15.2 0.0 6.6 6 1 0 6 6 6 1 HEAT-like repeat Arm PF00514.18 EIE90305.1 - 0.002 17.8 3.7 0.43 10.4 0.0 5.2 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat FAR1 PF03101.10 EIE90307.1 - 1.4e-05 25.4 0.3 4e-05 24.0 0.2 1.8 1 0 0 1 1 1 1 FAR1 DNA-binding domain F-box-like PF12937.2 EIE90308.1 - 0.027 14.1 0.4 0.24 11.1 0.0 2.3 2 0 0 2 2 2 0 F-box-like RRM_1 PF00076.17 EIE90309.1 - 3.7e-17 61.7 0.2 1.2e-12 47.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE90309.1 - 3.8e-13 49.2 0.0 2.4e-08 33.8 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE90309.1 - 1.2e-12 47.5 0.1 1.8e-05 24.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Folate_carrier PF01770.13 EIE90309.1 - 0.013 14.0 1.8 0.018 13.5 1.2 1.1 1 0 0 1 1 1 0 Reduced folate carrier Ycf1 PF05758.7 EIE90309.1 - 0.025 12.3 2.3 0.029 12.0 1.6 1.1 1 0 0 1 1 1 0 Ycf1 zf-Tim10_DDP PF02953.10 EIE90310.1 - 1.2e-23 82.1 0.1 1.4e-23 81.9 0.1 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF3398 PF11878.3 EIE90310.1 - 0.048 13.5 0.0 0.057 13.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3398) Sad1_UNC PF07738.8 EIE90311.1 - 3.7e-24 85.0 0.0 1.1e-23 83.5 0.0 1.9 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal DUF3584 PF12128.3 EIE90311.1 - 0.00045 17.7 16.7 0.00045 17.7 11.6 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3584) Cullin_Nedd8 PF10557.4 EIE90311.1 - 0.026 14.3 3.4 0.24 11.2 0.3 3.4 3 0 0 3 3 3 0 Cullin protein neddylation domain Prominin PF05478.6 EIE90311.1 - 0.11 10.0 24.8 0.21 9.0 3.1 3.2 2 1 1 3 3 3 0 Prominin Baculo_PEP_C PF04513.7 EIE90311.1 - 0.13 12.1 31.5 0.076 12.8 6.0 2.7 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Myosin_tail_1 PF01576.14 EIE90311.1 - 0.24 9.0 33.7 0.0079 13.9 11.9 2.0 2 0 0 2 2 2 0 Myosin tail DUF1492 PF07374.6 EIE90311.1 - 0.78 9.8 10.3 0.32 11.1 0.7 3.1 2 1 0 3 3 3 0 Protein of unknown function (DUF1492) Exonuc_VII_L PF02601.10 EIE90311.1 - 0.89 8.6 27.0 0.14 11.2 12.1 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit Reo_sigmaC PF04582.7 EIE90311.1 - 3 6.9 14.8 19 4.3 4.0 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF2077 PF09850.4 EIE90311.1 - 5.4 6.3 9.2 1 8.7 0.2 3.4 2 1 1 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2077) AAA_13 PF13166.1 EIE90311.1 - 5.6 5.2 28.5 0.084 11.3 12.4 2.1 2 0 0 2 2 2 0 AAA domain DUF3450 PF11932.3 EIE90311.1 - 7.3 5.7 40.3 0.27 10.4 3.4 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) DLH PF01738.13 EIE90312.1 - 7.5e-15 54.7 0.0 9.4e-15 54.4 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EIE90312.1 - 5.9e-06 26.1 0.0 7.8e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIE90312.1 - 0.004 17.0 0.0 0.005 16.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EIE90312.1 - 0.13 11.7 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Pex16 PF08610.5 EIE90313.1 - 6.4e-75 252.2 6.6 8.4e-75 251.8 4.6 1.1 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) WD40 PF00400.27 EIE90314.1 - 1.2e-37 126.4 18.3 6.6e-11 41.6 0.3 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 EIE90314.1 - 4.7e-06 26.4 0.0 0.0076 15.9 0.0 3.5 2 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A HIRA_B PF09453.5 EIE90314.1 - 6e-05 22.4 0.6 0.00014 21.2 0.4 1.7 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.7 EIE90314.1 - 0.056 13.1 1.3 1.1 9.0 0.0 3.5 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat HSF_DNA-bind PF00447.12 EIE90315.1 - 0.012 15.7 0.1 0.012 15.7 0.1 2.0 2 1 0 2 2 2 0 HSF-type DNA-binding TFIIE_alpha PF02002.12 EIE90315.1 - 0.03 13.8 8.3 0.044 13.2 0.5 2.8 2 1 0 2 2 2 0 TFIIE alpha subunit TPR_7 PF13176.1 EIE90315.1 - 0.045 13.5 1.1 0.16 11.8 0.8 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF2969 PF11184.3 EIE90315.1 - 0.07 13.2 1.2 0.11 12.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2969) Feld-I_B PF09252.5 EIE90315.1 - 0.072 12.9 0.2 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 Allergen Fel d I-B chain Tox-GHH PF15636.1 EIE90315.1 - 2 8.0 7.7 0.72 9.5 2.1 2.4 1 1 1 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin DUF740 PF05340.7 EIE90315.1 - 2.7 6.2 7.0 3.2 6.0 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF740) DUF1910 PF08928.5 EIE90315.1 - 8.3 6.4 11.0 1e+02 2.9 6.1 2.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1910) TFIIIC_sub6 PF10419.4 EIE90317.1 - 6.8e-09 35.0 0.3 1.1e-08 34.4 0.2 1.3 1 0 0 1 1 1 1 TFIIIC subunit UCR_UQCRX_QCR9 PF05365.7 EIE90318.1 - 1.3e-26 91.9 1.7 1.5e-26 91.7 1.2 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like DUF4203 PF13886.1 EIE90318.1 - 0.09 12.2 0.0 0.09 12.2 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4203) ParA PF10609.4 EIE90319.1 - 6.7e-17 61.1 1.2 1.2e-16 60.3 0.9 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EIE90319.1 - 8e-17 61.2 0.3 1e-16 60.9 0.2 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EIE90319.1 - 2.6e-09 37.2 0.0 2.5e-08 33.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain MipZ PF09140.6 EIE90319.1 - 1e-07 31.2 0.0 1.8e-07 30.5 0.0 1.4 1 1 0 1 1 1 1 ATPase MipZ Fer4_NifH PF00142.13 EIE90319.1 - 2.9e-05 23.3 0.1 4.3e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArsA_ATPase PF02374.10 EIE90319.1 - 0.00012 21.2 1.7 0.0014 17.7 1.0 2.0 2 0 0 2 2 2 1 Anion-transporting ATPase VirC1 PF07015.6 EIE90319.1 - 0.0046 16.0 0.2 0.0074 15.3 0.2 1.3 1 0 0 1 1 1 1 VirC1 protein SRP54 PF00448.17 EIE90319.1 - 0.035 13.5 0.4 0.059 12.8 0.2 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_25 PF13481.1 EIE90319.1 - 0.036 13.4 3.2 0.11 11.8 2.2 1.8 1 1 0 1 1 1 0 AAA domain NAD_Gly3P_dh_C PF07479.9 EIE90319.1 - 0.038 13.7 0.1 1.6 8.4 0.2 2.1 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus AAA_19 PF13245.1 EIE90319.1 - 0.12 12.1 4.0 1.4 8.7 0.5 2.4 2 1 0 2 2 2 0 Part of AAA domain CobA_CobO_BtuR PF02572.10 EIE90319.1 - 0.91 9.1 3.2 1.7 8.2 2.2 1.6 1 1 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Pkinase PF00069.20 EIE90320.1 - 4.9e-66 222.5 0.0 8.2e-66 221.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE90320.1 - 7.8e-36 123.4 0.0 1.5e-35 122.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.17 EIE90320.1 - 8.9e-19 66.9 24.0 1.3e-09 37.6 8.1 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 EIE90320.1 - 1e-09 38.7 0.1 2.7e-09 37.3 0.1 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Ribosomal_60s PF00428.14 EIE90320.1 - 0.26 11.7 4.9 0.5 10.8 3.4 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein C1_2 PF03107.11 EIE90320.1 - 0.33 11.1 21.0 0.88 9.7 7.3 2.8 2 0 0 2 2 2 0 C1 domain FYVE_2 PF02318.11 EIE90320.1 - 0.93 9.4 18.9 1.3 8.9 6.2 2.6 1 1 1 2 2 2 0 FYVE-type zinc finger C1_3 PF07649.7 EIE90320.1 - 6.8 6.8 18.2 6.7 6.8 0.7 2.8 2 0 0 2 2 2 0 C1-like domain TrkH PF02386.11 EIE90322.1 - 4.6e-54 183.3 9.6 2.5e-52 177.5 6.6 2.0 1 1 0 1 1 1 1 Cation transport protein MtrE PF04206.7 EIE90322.1 - 0.083 11.8 0.1 0.083 11.8 0.1 1.9 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit E DKCLD PF08068.7 EIE90323.1 - 3.4e-31 106.9 0.2 1.2e-29 102.0 0.1 2.6 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.13 EIE90323.1 - 7.1e-24 84.6 0.2 6.4e-21 75.0 0.1 3.6 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 EIE90323.1 - 1.1e-19 69.9 1.5 2.3e-19 68.8 1.1 1.6 1 0 0 1 1 1 1 PUA domain RNA_polI_A34 PF08208.6 EIE90323.1 - 0.069 12.8 17.6 0.11 12.1 12.2 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 BLVR PF06375.6 EIE90323.1 - 0.41 10.4 13.0 0.33 10.7 7.9 1.7 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) WD40 PF00400.27 EIE90324.1 - 4.4e-10 39.0 17.0 0.00066 19.4 1.8 6.1 5 1 0 5 5 5 4 WD domain, G-beta repeat DZR PF12773.2 EIE90324.1 - 1.8e-05 24.4 8.5 3.9e-05 23.3 5.9 1.6 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.1 EIE90324.1 - 0.00022 20.3 7.1 0.018 14.2 0.8 2.5 2 0 0 2 2 2 2 zinc-ribbon domain RWD PF05773.17 EIE90324.1 - 0.0016 18.2 0.1 0.0043 16.9 0.1 1.7 1 0 0 1 1 1 1 RWD domain zinc_ribbon_2 PF13240.1 EIE90324.1 - 1.7 8.2 18.3 0.094 12.2 2.0 3.0 3 0 0 3 3 3 0 zinc-ribbon domain Dynactin_p62 PF05502.8 EIE90325.1 - 4.1e-66 223.7 10.1 1.3e-37 129.7 0.7 2.4 1 1 1 2 2 2 2 Dynactin p62 family Acyltransferase PF01553.16 EIE90327.1 - 9.7e-13 47.6 0.0 1.4e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase HSF_DNA-bind PF00447.12 EIE90328.1 - 7e-34 116.1 0.9 1.7e-33 114.8 0.7 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding IncA PF04156.9 EIE90328.1 - 0.021 14.4 7.3 0.032 13.8 5.0 1.3 1 0 0 1 1 1 0 IncA protein DUF260 PF03195.9 EIE90328.1 - 0.19 12.0 1.1 0.81 9.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF260 NAD_kinase PF01513.16 EIE90329.1 - 3e-51 173.8 0.0 3.9e-51 173.5 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DDE_3 PF13358.1 EIE90330.1 - 3.4e-05 23.6 0.0 3.8e-05 23.4 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease KBP_C PF12309.3 EIE90331.1 - 0.072 12.0 0.1 0.099 11.5 0.0 1.1 1 0 0 1 1 1 0 KIF-1 binding protein C terminal DDE_3 PF13358.1 EIE90333.1 - 1e-05 25.3 0.0 1.1e-05 25.1 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease RasGEF PF00617.14 EIE90335.1 - 1.1e-54 185.0 0.7 3.1e-54 183.5 0.1 2.1 2 0 0 2 2 2 1 RasGEF domain SH3_1 PF00018.23 EIE90335.1 - 3.9e-08 32.5 0.1 3.9e-08 32.5 0.0 2.4 3 0 0 3 3 3 1 SH3 domain SH3_2 PF07653.12 EIE90335.1 - 7e-08 31.8 0.1 1.3e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EIE90335.1 - 3.3e-06 26.5 0.1 9.3e-06 25.1 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain RasGEF_N PF00618.15 EIE90335.1 - 0.00059 19.9 10.6 0.019 15.0 0.1 4.7 4 1 1 5 5 5 2 RasGEF N-terminal motif DUF2951 PF11166.3 EIE90335.1 - 0.052 13.4 5.3 0.034 13.9 1.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) GTP_EFTU PF00009.22 EIE90336.1 - 6.6e-57 191.9 0.0 1.2e-56 191.1 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EIE90336.1 - 9.7e-37 125.1 0.0 2.4e-36 123.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EIE90336.1 - 5e-16 58.5 1.1 5e-16 58.5 0.7 2.4 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EIE90336.1 - 0.00097 19.0 0.3 0.0029 17.5 0.2 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 EIE90336.1 - 0.0013 18.3 0.4 0.0013 18.3 0.3 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 4 Semialdhyde_dhC PF02774.13 EIE90336.1 - 0.12 12.2 0.3 0.32 10.8 0.0 1.8 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain RWD PF05773.17 EIE90337.1 - 2.3e-09 37.1 12.0 0.00023 21.0 0.9 3.5 1 1 2 3 3 3 3 RWD domain Potyvirid-P3 PF13608.1 EIE90337.1 - 0.05 12.7 0.9 0.066 12.3 0.6 1.1 1 0 0 1 1 1 0 Protein P3 of Potyviral polyprotein RCC1 PF00415.13 EIE90338.1 - 1.3e-12 47.7 10.8 1.1e-05 25.5 0.3 4.5 4 0 0 4 4 4 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EIE90338.1 - 1.5e-07 30.8 8.6 4.8e-06 26.0 0.4 4.6 6 1 0 6 6 6 2 Regulator of chromosome condensation (RCC1) repeat zf-RING_2 PF13639.1 EIE90339.1 - 4e-11 42.5 8.7 5.3e-11 42.1 6.0 1.2 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EIE90339.1 - 1.3e-06 28.3 6.8 3.4e-06 27.0 4.7 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EIE90339.1 - 8.8e-06 25.2 7.4 1.3e-05 24.6 5.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIE90339.1 - 2.2e-05 24.0 7.7 3.6e-05 23.4 5.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EIE90339.1 - 0.00012 21.6 6.7 0.00017 21.1 4.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 EIE90339.1 - 0.00085 18.9 4.5 0.0014 18.2 3.1 1.4 1 0 0 1 1 1 1 PHD-finger zf-C3HC4_2 PF13923.1 EIE90339.1 - 0.00086 19.2 9.6 0.0013 18.7 6.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EIE90339.1 - 0.024 14.4 4.6 0.038 13.8 3.2 1.5 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-HC5HC2H_2 PF13832.1 EIE90339.1 - 0.044 13.7 0.6 0.044 13.7 0.4 1.4 2 0 0 2 2 2 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EIE90339.1 - 0.21 11.7 4.9 0.061 13.4 1.7 1.4 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-RING_UBOX PF13445.1 EIE90339.1 - 0.21 11.3 4.0 0.38 10.5 1.9 2.0 1 1 1 2 2 2 0 RING-type zinc-finger zf-RING_4 PF14570.1 EIE90339.1 - 1.7 8.3 7.8 15 5.2 5.7 2.0 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.3 EIE90339.1 - 2.1 7.9 5.0 3.3 7.3 3.5 1.4 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.1 EIE90339.1 - 9.2 6.2 9.9 42 4.1 6.9 2.0 1 1 2 3 3 3 0 zinc finger of C3HC4-type, RING Epimerase PF01370.16 EIE90340.1 - 5.7e-46 156.8 0.0 7.2e-46 156.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EIE90340.1 - 1.3e-12 46.9 0.0 1.8e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EIE90340.1 - 8.2e-12 44.5 0.0 1e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 EIE90340.1 - 3e-11 42.7 0.1 8.1e-07 28.2 0.0 2.1 1 1 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.10 EIE90340.1 - 1.5e-08 33.9 0.1 6.5e-05 21.9 0.1 2.9 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EIE90340.1 - 4.2e-05 23.6 0.0 6.2e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EIE90340.1 - 0.0082 16.0 0.0 0.019 14.8 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase IPK PF03770.11 EIE90341.1 - 1.9e-49 167.9 0.0 3.8e-49 167.0 0.0 1.5 1 1 0 1 1 1 1 Inositol polyphosphate kinase Podoplanin PF05808.6 EIE90343.1 - 0.025 14.1 0.0 0.033 13.7 0.0 1.2 1 0 0 1 1 1 0 Podoplanin Ribosomal_L21e PF01157.13 EIE90344.1 - 4.8e-43 145.0 4.7 6.7e-43 144.5 3.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L21e DUF1989 PF09347.5 EIE90344.1 - 0.0022 17.4 0.0 0.0029 17.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) DUF3865 PF12981.2 EIE90344.1 - 0.07 12.9 0.1 0.088 12.5 0.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3865) Surface_Ag_2 PF01617.12 EIE90344.1 - 0.084 12.0 0.2 0.1 11.8 0.1 1.3 1 0 0 1 1 1 0 Surface antigen LRS4 PF10422.4 EIE90344.1 - 0.098 11.9 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 Ribosomal_S4 PF00163.14 EIE90345.1 - 4.2e-28 97.5 1.0 7.6e-28 96.7 0.7 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 EIE90345.1 - 3.1e-13 48.9 1.4 3.1e-13 48.9 1.0 2.4 3 0 0 3 3 3 1 S4 domain Fz PF01392.17 EIE90347.1 - 0.011 16.0 0.6 0.26 11.6 0.1 2.0 1 1 1 2 2 2 0 Fz domain Carb_anhydrase PF00194.16 EIE90347.1 - 0.081 11.8 0.3 0.49 9.3 0.1 1.9 1 1 1 2 2 2 0 Eukaryotic-type carbonic anhydrase EspB PF05802.6 EIE90349.1 - 0.006 15.5 3.4 0.007 15.3 2.4 1.0 1 0 0 1 1 1 1 Enterobacterial EspB protein SH3_9 PF14604.1 EIE90350.1 - 1.1e-10 40.8 0.0 1.8e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EIE90350.1 - 3.1e-05 23.2 0.0 5.1e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EIE90350.1 - 0.0013 18.1 0.0 0.0027 17.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SAPS PF04499.10 EIE90350.1 - 0.005 15.5 10.9 0.0071 15.0 7.5 1.3 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein DUF1510 PF07423.6 EIE90350.1 - 0.16 11.2 23.0 1.1 8.5 16.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Syndecan PF01034.15 EIE90350.1 - 0.27 10.9 5.3 0.32 10.6 0.1 2.7 2 0 0 2 2 2 0 Syndecan domain MIP-T3 PF10243.4 EIE90350.1 - 0.41 9.0 28.0 0.71 8.2 19.4 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Utp14 PF04615.8 EIE90350.1 - 0.6 8.2 24.0 0.85 7.7 16.6 1.1 1 0 0 1 1 1 0 Utp14 protein TFIIF_alpha PF05793.7 EIE90350.1 - 7.9 4.7 33.1 11 4.2 23.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) eIF-3c_N PF05470.7 EIE90350.1 - 8.7 4.3 14.0 12 3.8 9.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus zf-C2H2_4 PF13894.1 EIE90351.1 - 4.3e-05 23.5 11.9 0.024 14.9 0.2 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EIE90351.1 - 0.00022 21.3 17.2 0.012 15.9 0.6 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIE90351.1 - 0.04 14.2 12.1 0.28 11.5 0.5 3.1 3 0 0 3 3 3 0 Zinc-finger double domain DUF3984 PF13136.1 EIE90351.1 - 3.1 6.9 7.4 0.085 12.0 0.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3984) CPSase_L_D2 PF02786.12 EIE90353.1 - 7.2e-112 371.7 0.1 8.8e-84 280.0 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.17 EIE90353.1 - 4.7e-47 158.7 0.0 1e-46 157.6 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 EIE90353.1 - 1.2e-45 155.3 0.0 2.2e-45 154.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I OTCace_N PF02729.16 EIE90353.1 - 6.2e-44 149.1 0.0 1.3e-43 148.0 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.14 EIE90353.1 - 8e-43 145.1 0.0 2e-42 143.8 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_L_chain PF00289.17 EIE90353.1 - 1.5e-41 140.8 0.0 1.1e-21 77.0 0.0 3.1 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain OTCace PF00185.19 EIE90353.1 - 7.1e-38 129.9 0.0 1.8e-37 128.6 0.0 1.8 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ATP-grasp_4 PF13535.1 EIE90353.1 - 1.6e-33 116.0 0.1 6.7e-23 81.3 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 EIE90353.1 - 4.1e-21 75.0 0.0 1.2e-11 44.0 0.0 3.6 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon MGS PF02142.17 EIE90353.1 - 2.6e-19 68.9 0.0 2e-18 66.0 0.0 2.7 3 0 0 3 3 2 1 MGS-like domain Dala_Dala_lig_C PF07478.8 EIE90353.1 - 3.9e-15 55.7 0.6 6.5e-08 32.2 0.0 2.8 2 1 1 3 3 3 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EIE90353.1 - 2.6e-13 49.7 0.1 6.6e-07 28.8 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_3 PF02655.9 EIE90353.1 - 3.3e-06 27.0 0.4 0.082 12.7 0.0 2.9 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.8 EIE90353.1 - 3.6e-05 23.3 0.1 0.0009 18.7 0.1 2.4 1 1 0 1 1 1 1 Peptidase C26 NmrA PF05368.8 EIE90353.1 - 0.00037 19.8 0.0 0.00082 18.6 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family SPRY PF00622.23 EIE90354.1 - 5e-24 84.7 0.4 1e-23 83.7 0.3 1.5 1 0 0 1 1 1 1 SPRY domain LisH PF08513.6 EIE90354.1 - 1.5e-05 24.5 0.2 3.2e-05 23.5 0.1 1.6 1 0 0 1 1 1 1 LisH MFMR PF07777.6 EIE90354.1 - 0.14 12.0 5.7 0.36 10.7 3.9 1.7 1 1 0 1 1 1 0 G-box binding protein MFMR zf-H2C2 PF09337.5 EIE90355.1 - 0.00027 20.2 0.2 0.00059 19.1 0.1 1.6 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Xpo1 PF08389.7 EIE90357.1 - 5.3e-27 94.5 3.7 1.1e-26 93.4 0.9 2.9 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.14 EIE90357.1 - 1.2e-05 25.0 2.8 0.00064 19.5 1.3 3.0 3 0 0 3 3 3 1 Importin-beta N-terminal domain Ribosomal_L30 PF00327.15 EIE90358.1 - 6.1e-11 41.7 0.1 8.1e-11 41.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Sugar_tr PF00083.19 EIE90359.1 - 1.1e-103 347.2 24.1 1.2e-103 347.1 16.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIE90359.1 - 9.5e-34 116.6 33.8 9e-32 110.1 15.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Folate_carrier PF01770.13 EIE90359.1 - 9e-06 24.4 0.1 1.5e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 Reduced folate carrier MFS_2 PF13347.1 EIE90359.1 - 0.004 15.6 13.2 0.004 15.6 9.2 3.5 2 2 1 4 4 4 2 MFS/sugar transport protein OATP PF03137.15 EIE90359.1 - 0.007 14.4 2.3 1 7.3 0.1 2.3 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family DUF1228 PF06779.9 EIE90359.1 - 0.14 12.1 5.9 0.21 11.6 0.3 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1228) ADH_N PF08240.7 EIE90360.1 - 5.1e-29 100.2 4.3 5.1e-29 100.2 3.0 2.1 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIE90360.1 - 8.7e-17 60.8 0.1 1.7e-16 59.9 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIE90360.1 - 0.00011 23.0 0.0 0.00029 21.7 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase HI0933_like PF03486.9 EIE90360.1 - 0.0006 18.4 0.1 0.00097 17.7 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_7 PF13241.1 EIE90360.1 - 0.0016 18.6 0.0 0.0031 17.7 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Pyr_redox PF00070.22 EIE90360.1 - 0.0017 18.6 0.2 0.0037 17.6 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EIE90360.1 - 0.0021 17.1 0.1 0.0031 16.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EIE90360.1 - 0.0067 15.3 0.1 0.011 14.7 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Methyltransf_18 PF12847.2 EIE90360.1 - 0.031 14.8 0.0 0.075 13.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain TrkA_N PF02254.13 EIE90360.1 - 0.042 13.8 0.0 0.083 12.8 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.13 EIE90360.1 - 0.061 12.9 0.1 0.14 11.8 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.1 EIE90360.1 - 0.073 13.0 0.0 0.23 11.5 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain 2-Hacid_dh_C PF02826.14 EIE90360.1 - 0.12 11.5 0.1 0.23 10.5 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pkinase PF00069.20 EIE90361.1 - 9.2e-51 172.4 3.4 6.5e-31 107.4 0.0 3.1 2 1 1 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 EIE90361.1 - 2e-21 76.2 1.0 7.4e-17 61.2 0.0 2.7 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EIE90361.1 - 0.0097 14.8 0.1 0.065 12.1 0.0 2.1 2 0 0 2 2 2 1 Kinase-like UTP15_C PF09384.5 EIE90363.1 - 0.0073 16.0 0.0 0.022 14.4 0.0 1.8 1 0 0 1 1 1 1 UTP15 C terminal DUF3666 PF12408.3 EIE90363.1 - 0.047 12.7 0.4 0.29 10.2 0.1 2.4 2 0 0 2 2 2 0 Ribose-5-phosphate isomerase ThiF PF00899.16 EIE90364.1 - 3.4e-39 133.7 0.1 1e-38 132.2 0.0 1.7 2 0 0 2 2 2 1 ThiF family UBACT PF02134.16 EIE90364.1 - 1.2e-18 66.4 0.1 3.4e-18 64.9 0.1 1.8 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EIE90364.1 - 1.8e-17 62.4 2.6 1.8e-17 62.4 1.8 1.7 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.15 EIE90364.1 - 9e-05 22.5 0.0 0.0002 21.4 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 EIE90364.1 - 0.045 14.1 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Gmx_para_CXXCG PF09535.5 EIE90364.1 - 0.061 12.3 0.0 10 5.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (Gmx_para_CXXCG) SPOB_ab PF14682.1 EIE90365.1 - 0.034 13.9 0.1 0.053 13.3 0.1 1.3 1 0 0 1 1 1 0 Sporulation initiation phospho-transferase B, C-terminal zf-CCHC PF00098.18 EIE90366.1 - 4.8e-07 29.3 11.4 6.5e-05 22.6 0.7 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.1 EIE90366.1 - 0.00065 19.1 3.1 0.00065 19.1 2.1 2.3 1 1 1 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.1 EIE90366.1 - 0.00072 19.1 3.9 0.086 12.5 0.3 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.1 EIE90366.1 - 0.26 11.0 10.3 0.34 10.6 1.4 2.7 1 1 1 2 2 2 0 Zinc knuckle RVT_1 PF00078.22 EIE90367.1 - 1.4e-31 109.5 0.0 2.2e-31 108.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SRF-TF PF00319.13 EIE90368.1 - 1.6e-22 78.4 0.2 2.5e-22 77.8 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) SURF6 PF04935.7 EIE90370.1 - 1.5e-34 119.1 58.4 1.5e-34 119.1 40.5 2.6 2 1 0 2 2 2 1 Surfeit locus protein 6 RRP14 PF15459.1 EIE90370.1 - 9.6e-21 73.6 6.0 9.6e-21 73.6 4.1 6.9 5 2 0 5 5 5 1 60S ribosome biogenesis protein Rrp14 DUF1762 PF08574.5 EIE90370.1 - 3.3 8.2 9.6 18 5.8 3.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1762) Sel1 PF08238.7 EIE90371.1 - 2.8e-16 59.5 26.3 4.9e-08 33.3 0.4 7.5 7 0 0 7 7 7 4 Sel1 repeat RNA_pol_Rpb4 PF03874.11 EIE90371.1 - 0.0043 17.0 2.7 0.22 11.5 0.0 2.7 2 0 0 2 2 2 1 RNA polymerase Rpb4 TPR_16 PF13432.1 EIE90371.1 - 0.0077 16.8 0.3 0.0077 16.8 0.2 4.4 3 2 4 7 7 7 1 Tetratricopeptide repeat TPR_11 PF13414.1 EIE90371.1 - 0.011 15.3 17.0 0.019 14.6 3.7 4.1 3 1 2 5 5 5 0 TPR repeat DUF3964 PF13107.1 EIE90371.1 - 0.016 15.4 0.1 0.65 10.2 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3964) TPR_2 PF07719.12 EIE90371.1 - 0.021 14.7 1.3 0.021 14.7 0.9 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.23 EIE90371.1 - 0.025 14.1 2.0 0.025 14.1 1.4 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_21 PF09976.4 EIE90371.1 - 0.06 13.2 8.5 0.03 14.2 1.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 EIE90371.1 - 0.13 12.6 8.9 0.18 12.1 0.6 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 EIE90371.1 - 3.1 7.8 7.2 2.9 7.8 0.4 4.0 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 EIE90371.1 - 3.8 8.3 7.9 3.8 8.4 0.1 4.1 4 1 1 5 5 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 EIE90371.1 - 4.9 7.1 19.7 2.4 8.1 2.5 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat AA_permease PF00324.16 EIE90372.1 - 1.5e-118 396.2 40.3 1.8e-118 395.9 27.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EIE90372.1 - 1e-36 126.4 45.3 1.5e-36 125.8 31.4 1.2 1 0 0 1 1 1 1 Amino acid permease DUF3593 PF12159.3 EIE90372.1 - 0.032 13.9 1.9 0.093 12.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3593) UPF0239 PF06783.6 EIE90373.1 - 0.11 12.4 0.2 0.22 11.4 0.0 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0239) FAP PF07174.6 EIE90373.1 - 0.15 11.3 9.6 0.17 11.1 6.7 1.0 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) ATP-synt_8 PF00895.15 EIE90373.1 - 0.18 12.0 1.7 0.27 11.4 1.2 1.2 1 0 0 1 1 1 0 ATP synthase protein 8 FTHFS PF01268.14 EIE90374.1 - 1e-266 885.3 0.4 1.6e-266 884.6 0.0 1.4 2 0 0 2 2 2 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 EIE90374.1 - 2.7e-66 221.5 0.9 2.7e-66 221.5 0.7 2.1 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 EIE90374.1 - 1.1e-42 144.8 0.7 2.5e-42 143.5 0.5 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain AdoHcyase_NAD PF00670.16 EIE90374.1 - 0.087 12.6 3.0 7.9 6.2 0.4 3.1 2 1 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Peptidase_M28 PF04389.12 EIE90376.1 - 6.3e-14 52.1 0.0 9.1e-14 51.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Rap_GAP PF02145.10 EIE90377.1 - 2.8e-47 160.5 0.0 7.1e-47 159.2 0.0 1.7 1 0 0 1 1 1 1 Rap/ran-GAP NAP PF00956.13 EIE90378.1 - 2.4e-81 272.4 10.1 2.4e-81 272.4 7.0 2.0 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) DUF4295 PF14128.1 EIE90378.1 - 0.019 14.5 0.8 0.046 13.3 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4295) TFIIE-A_C-term PF11521.3 EIE90378.1 - 0.046 13.6 0.8 0.046 13.6 0.6 3.1 2 1 1 3 3 3 0 C-terminal general transcription factor TFIIE alpha TFIIA PF03153.8 EIE90378.1 - 6.7 6.5 22.0 0.42 10.4 10.1 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Lar_restr_allev PF14354.1 EIE90379.1 - 0.089 13.1 0.1 0.21 11.8 0.1 1.5 1 0 0 1 1 1 0 Restriction alleviation protein Lar ATP-synt_C PF00137.16 EIE90380.1 - 1.7e-28 98.2 32.3 6.6e-16 57.9 7.0 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Asp PF00026.18 EIE90381.1 - 3.7e-48 164.4 5.8 1.1e-47 162.8 4.0 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIE90381.1 - 6.1e-07 29.5 3.2 1.1e-06 28.6 1.9 1.7 1 1 1 2 2 2 1 Xylanase inhibitor N-terminal ECH PF00378.15 EIE90382.1 - 4.6e-31 107.7 0.0 7.5e-31 107.1 0.0 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Sigma70_r1_1 PF03979.9 EIE90382.1 - 0.072 13.0 2.1 0.18 11.7 1.4 1.6 1 0 0 1 1 1 0 Sigma-70 factor, region 1.1 MFS_1 PF07690.11 EIE90383.1 - 2.3e-21 75.8 51.9 2.2e-19 69.4 18.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EIE90383.1 - 0.00033 19.1 14.2 0.00033 19.1 9.9 1.4 1 1 0 1 1 1 1 MFS/sugar transport protein S10_plectin PF03501.10 EIE90384.1 - 1.3e-42 143.5 0.0 1.5e-42 143.3 0.0 1.1 1 0 0 1 1 1 1 Plectin/S10 domain TrmB PF01978.14 EIE90384.1 - 0.11 12.2 0.0 0.28 10.9 0.0 1.6 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB DUF2250 PF10007.4 EIE90384.1 - 0.17 11.7 1.0 13 5.8 0.3 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) Rhodanese PF00581.15 EIE90385.1 - 1.9e-09 37.8 0.1 1e-08 35.4 0.0 2.3 3 0 0 3 3 3 1 Rhodanese-like domain FB_lectin PF07367.6 EIE90385.1 - 0.027 14.0 0.0 0.046 13.3 0.0 1.4 1 0 0 1 1 1 0 Fungal fruit body lectin ABC_membrane_2 PF06472.10 EIE90386.1 - 0.00048 19.3 9.3 1.2 8.1 0.1 4.3 4 0 0 4 4 4 4 ABC transporter transmembrane region 2 Velvet PF11754.3 EIE90387.1 - 5.6e-31 107.7 0.4 3e-30 105.3 0.3 1.9 1 1 0 1 1 1 1 Velvet factor CYSTM PF12734.2 EIE90388.1 - 0.00023 21.1 5.9 0.00023 21.1 4.1 3.7 1 1 1 2 2 2 1 Cysteine-rich TM module stress tolerance RCR PF12273.3 EIE90388.1 - 3 8.4 13.1 3.4 8.2 9.1 1.1 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red DUF2415 PF10313.4 EIE90389.1 - 3.5e-15 55.3 0.3 2.1e-14 52.9 0.0 2.1 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) WD40 PF00400.27 EIE90389.1 - 1.4e-05 24.7 1.8 8.7e-05 22.2 0.1 2.9 3 1 1 4 4 4 1 WD domain, G-beta repeat Pkinase PF00069.20 EIE90390.1 - 2.9e-62 210.1 0.0 4e-62 209.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE90390.1 - 7.5e-44 149.7 0.0 1.1e-43 149.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE90390.1 - 4.2e-06 25.9 0.0 3.9e-05 22.7 0.0 2.2 2 1 0 2 2 2 1 Kinase-like APH PF01636.18 EIE90390.1 - 0.076 12.7 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Mitofilin PF09731.4 EIE90391.1 - 0.071 11.7 4.3 0.07 11.7 3.0 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF4546 PF15079.1 EIE90391.1 - 0.071 12.2 0.4 0.071 12.2 0.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4546) TBPIP PF07106.8 EIE90391.1 - 0.075 12.5 1.6 0.075 12.5 1.1 1.0 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) GlutR_dimer PF00745.15 EIE90391.1 - 0.26 11.2 1.7 0.31 10.9 1.2 1.1 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, dimerisation domain DivIC PF04977.10 EIE90391.1 - 0.49 9.9 4.9 0.33 10.4 2.5 1.4 1 1 0 1 1 1 0 Septum formation initiator RINT1_TIP1 PF04437.8 EIE90392.1 - 1.2e-76 258.3 18.8 5.1e-48 163.8 6.7 2.2 1 1 1 2 2 2 2 RINT-1 / TIP-1 family DSPc PF00782.15 EIE90392.1 - 1.3e-19 70.0 0.6 1.3e-19 70.0 0.4 2.4 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain DUF2999 PF11212.3 EIE90392.1 - 0.27 11.3 4.2 2.6 8.1 0.2 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF2999) MFS_1 PF07690.11 EIE90393.1 - 1.6e-22 79.7 20.5 9.6e-21 73.8 14.1 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily ESSS PF10183.4 EIE90393.1 - 0.033 14.5 0.2 0.098 13.0 0.1 1.8 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) EF_assoc_1 PF08355.7 EIE90393.1 - 0.12 11.6 0.7 0.23 10.7 0.1 1.8 2 0 0 2 2 2 0 EF hand associated Gln-synt_C PF00120.19 EIE90394.1 - 2.5e-65 220.2 0.0 3.3e-65 219.7 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain DUF515 PF04415.7 EIE90395.1 - 2.8 6.0 10.6 3.3 5.8 7.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) DrrA_P4M PF14860.1 EIE90396.1 - 0.07 12.8 0.6 0.2 11.4 0.4 1.8 1 1 0 1 1 1 0 DrrA phosphatidylinositol 4-phosphate binding domain zf-CCHC PF00098.18 EIE90399.1 - 6.4e-05 22.6 9.0 0.04 13.8 1.2 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.1 EIE90399.1 - 0.19 11.4 11.3 0.4 10.4 1.1 2.5 1 1 1 2 2 2 0 Zinc knuckle HNH PF01844.18 EIE90399.1 - 0.38 10.6 6.0 7.3 6.5 0.5 3.4 3 0 0 3 3 3 0 HNH endonuclease zf-CCHC_4 PF14392.1 EIE90399.1 - 5.5 6.7 9.3 11 5.7 1.6 2.5 2 0 0 2 2 2 0 Zinc knuckle DDE_3 PF13358.1 EIE90400.1 - 5.9e-15 55.2 0.1 1.1e-14 54.4 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Bap31 PF05529.7 EIE90402.1 - 0.11 11.9 0.8 0.12 11.8 0.6 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF3439 PF11921.3 EIE90402.1 - 0.14 11.8 6.1 0.19 11.4 4.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Striatin PF08232.7 EIE90402.1 - 0.31 11.3 3.6 0.23 11.7 0.9 1.8 1 1 1 2 2 2 0 Striatin family DDE_3 PF13358.1 EIE90403.1 - 1.2e-15 57.4 0.0 1.9e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_ISAZ013 PF07592.6 EIE90403.1 - 0.048 12.4 0.0 0.066 11.9 0.0 1.1 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain Kelch_5 PF13854.1 EIE90404.1 - 8.6e-17 60.6 0.3 6.3e-05 22.8 0.0 3.6 3 0 0 3 3 3 3 Kelch motif Kelch_4 PF13418.1 EIE90404.1 - 2.1e-14 53.0 0.2 0.00054 19.6 0.0 4.4 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_6 PF13964.1 EIE90404.1 - 7.1e-14 51.2 1.2 0.0051 16.9 0.0 4.4 3 1 1 4 4 4 3 Kelch motif Kelch_3 PF13415.1 EIE90404.1 - 9.5e-13 47.9 1.3 2.2e-06 27.6 0.0 5.3 5 0 0 5 5 5 2 Galactose oxidase, central domain BTB PF00651.26 EIE90404.1 - 1.7e-07 31.2 0.1 2.9e-07 30.4 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain Kelch_1 PF01344.20 EIE90404.1 - 7.6e-07 28.5 0.0 0.61 9.6 0.0 3.4 3 0 0 3 3 3 3 Kelch motif Kelch_2 PF07646.10 EIE90404.1 - 9.4e-07 28.3 0.3 0.14 11.9 0.0 4.1 4 0 0 4 4 4 2 Kelch motif AA_permease_2 PF13520.1 EIE90407.1 - 3.1e-56 190.7 55.4 3.5e-56 190.5 37.5 1.6 1 1 1 2 2 2 1 Amino acid permease AA_permease PF00324.16 EIE90407.1 - 5.9e-38 130.4 49.1 7.8e-38 130.0 34.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.1 EIE90407.1 - 1.1e-07 31.6 4.9 1.1e-07 31.6 3.4 4.3 3 0 0 3 3 3 1 C-terminus of AA_permease DUF2410 PF10307.4 EIE90408.1 - 1.2e-27 96.5 0.2 7.2e-27 94.0 0.2 2.0 1 1 0 1 1 1 1 Hypothetical protein (DUF2410) DUF572 PF04502.8 EIE90409.1 - 7.1e-36 124.0 8.7 2.4e-17 63.1 6.5 2.0 1 1 1 2 2 2 2 Family of unknown function (DUF572) ALMT PF11744.3 EIE90410.1 - 3.2e-18 65.5 11.3 3.2e-18 65.5 7.9 2.1 1 1 0 2 2 2 1 Aluminium activated malate transporter FUSC_2 PF13515.1 EIE90410.1 - 1.5e-10 41.0 17.8 2.4e-10 40.4 11.8 1.7 1 1 0 1 1 1 1 Fusaric acid resistance protein-like FUSC PF04632.7 EIE90410.1 - 2e-10 39.7 4.4 4.8e-10 38.5 3.1 1.6 1 1 0 1 1 1 1 Fusaric acid resistance protein family DUF4625 PF15418.1 EIE90411.1 - 0.0059 16.7 0.0 0.008 16.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4625) MFS_1 PF07690.11 EIE90412.1 - 1.9e-37 128.8 29.9 1.9e-37 128.8 20.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIE90412.1 - 1.7e-10 40.0 14.6 1.7e-10 40.0 10.1 2.1 1 1 1 2 2 2 1 Sugar (and other) transporter DUF1298 PF06974.8 EIE90412.1 - 0.021 14.6 1.2 0.34 10.6 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1298) ETC_C1_NDUFA5 PF04716.9 EIE90413.1 - 3e-23 81.0 0.8 5.9e-23 80.1 0.6 1.5 1 0 0 1 1 1 1 ETC complex I subunit conserved region Oxysterol_BP PF01237.13 EIE90414.1 - 6.9e-64 215.5 4.3 8.7e-64 215.2 2.9 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein His_Phos_2 PF00328.17 EIE90415.1 - 1.3e-32 113.4 0.6 1.7e-32 113.1 0.4 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) MULE PF10551.4 EIE90416.1 - 7.3e-09 35.6 0.1 2.8e-08 33.8 0.0 2.1 2 0 0 2 2 2 1 MULE transposase domain DDE_Tnp_IS240 PF13610.1 EIE90416.1 - 0.00021 21.2 0.2 1.8 8.5 0.0 3.7 4 0 0 4 4 4 2 DDE domain FAR1 PF03101.10 EIE90416.1 - 0.037 14.5 1.3 0.11 13.0 0.9 1.8 1 0 0 1 1 1 0 FAR1 DNA-binding domain Herpes_U30 PF04523.8 EIE90418.1 - 0.012 13.1 0.1 0.018 12.5 0.0 1.2 1 0 0 1 1 1 0 Herpes virus tegument protein U30 DUF1664 PF07889.7 EIE90418.1 - 0.015 15.0 6.1 0.04 13.7 4.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Jnk-SapK_ap_N PF09744.4 EIE90418.1 - 0.08 12.9 11.6 0.15 12.0 8.0 1.5 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Phage_integrase PF00589.17 EIE90419.1 - 0.00061 19.5 0.7 0.001 18.7 0.5 1.5 1 1 1 2 2 2 1 Phage integrase family DDE_3 PF13358.1 EIE90420.1 - 0.00099 18.8 0.2 0.0027 17.4 0.1 1.9 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE90420.1 - 0.021 14.8 0.1 0.39 10.8 0.0 2.8 2 0 0 2 2 2 0 Transposase rve PF00665.21 EIE90422.1 - 1.4e-23 83.2 0.0 3.2e-23 82.0 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 EIE90422.1 - 6.5e-12 44.9 0.2 1.2e-11 44.0 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 EIE90422.1 - 0.0029 16.9 0.1 0.006 15.9 0.0 1.6 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger RVT_1 PF00078.22 EIE90423.1 - 7.1e-17 61.4 0.0 1.3e-16 60.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 EIE90423.1 - 1.7e-06 28.4 0.1 9.4e-06 26.0 0.0 2.4 2 0 0 2 2 2 1 Aspartyl protease Retrotrans_gag PF03732.12 EIE90423.1 - 4.8e-06 26.5 0.9 1.3e-05 25.1 0.0 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein UBN2_2 PF14227.1 EIE90423.1 - 1.7e-05 24.3 0.8 0.00067 19.2 0.1 3.7 4 1 0 4 4 4 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EIE90423.1 - 0.00029 20.5 1.0 0.16 11.7 0.1 3.0 3 0 0 3 3 3 2 gag-polypeptide of LTR copia-type gag-asp_proteas PF13975.1 EIE90423.1 - 0.00067 19.4 0.0 0.0014 18.3 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.22 EIE90424.1 - 3.3e-11 42.9 0.3 9e-11 41.5 0.2 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 EIE90424.1 - 4e-06 27.2 0.2 8.7e-06 26.1 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 EIE90424.1 - 1.2e-05 25.1 0.1 3.4e-05 23.6 0.1 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EIE90424.1 - 3.2e-05 23.6 0.0 7.4e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.5 EIE90424.1 - 0.065 12.7 0.0 0.2 11.2 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease rve PF00665.21 EIE90425.1 - 2.6e-10 40.4 0.0 8.9e-10 38.7 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.19 EIE90425.1 - 9.4e-08 31.6 2.4 1.9e-07 30.6 1.6 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 EIE90425.1 - 0.0019 17.8 1.0 0.0044 16.6 0.7 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain rve_3 PF13683.1 EIE90425.1 - 0.0035 16.8 0.0 0.01 15.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain YcgR_2 PF12945.2 EIE90425.1 - 0.096 12.5 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Flagellar protein YcgR zf-CCHC PF00098.18 EIE90426.1 - 0.00013 21.7 3.7 0.00013 21.7 2.6 3.4 3 0 0 3 3 3 1 Zinc knuckle eIF3g PF12353.3 EIE90426.1 - 0.79 9.6 15.3 3.5 7.5 1.0 3.3 2 1 1 3 3 3 0 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_2 PF13696.1 EIE90426.1 - 1.9 8.0 15.2 0.58 9.7 0.4 2.9 3 0 0 3 3 3 0 Zinc knuckle Exo_endo_phos_2 PF14529.1 EIE90427.1 - 7.7e-08 31.9 0.3 1.5e-07 31.0 0.2 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EIE90427.1 - 1.8e-07 31.3 2.1 3.5e-07 30.4 1.4 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Effector_1 PF04518.7 EIE90427.1 - 0.11 11.4 0.5 0.16 10.8 0.3 1.1 1 0 0 1 1 1 0 Effector from type III secretion system HTH_Tnp_Tc3_2 PF01498.13 EIE90429.1 - 1.5e-09 37.7 0.1 3.2e-09 36.6 0.1 1.5 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.1 EIE90429.1 - 4.5e-05 23.2 0.0 8.5e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease IL12 PF03039.9 EIE90429.1 - 0.023 13.8 0.1 0.04 13.0 0.1 1.4 1 0 0 1 1 1 0 Interleukin-12 alpha subunit HTH_Tnp_Tc3_2 PF01498.13 EIE90430.1 - 1.4e-16 60.2 1.9 5.1e-16 58.4 0.2 2.3 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 EIE90430.1 - 4.4e-09 36.4 0.1 1.3e-08 34.9 0.1 1.8 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EIE90430.1 - 1.4e-08 34.0 0.4 1.1e-05 24.8 0.0 2.9 3 0 0 3 3 2 1 Homeodomain-like domain DDE_3 PF13358.1 EIE90430.1 - 2.1e-08 34.0 0.1 3.7e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_7 PF02796.10 EIE90430.1 - 2.3e-07 30.5 5.5 8.8e-06 25.4 0.4 3.2 2 1 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_32 PF13565.1 EIE90430.1 - 2.9e-07 31.1 0.1 2.4e-05 25.0 0.0 3.2 2 1 1 3 3 3 1 Homeodomain-like domain HTH_11 PF08279.7 EIE90430.1 - 4.7e-06 26.1 1.2 0.00046 19.7 0.1 2.6 2 1 0 2 2 2 1 HTH domain HTH_36 PF13730.1 EIE90430.1 - 5.5e-06 26.4 1.3 0.00023 21.2 0.3 3.0 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_38 PF13936.1 EIE90430.1 - 8.3e-05 22.0 0.6 0.00075 19.0 0.0 2.5 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_28 PF13518.1 EIE90430.1 - 0.0001 22.2 0.0 0.026 14.5 0.0 3.2 3 0 0 3 3 2 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.1 EIE90430.1 - 0.00014 20.9 0.1 0.1 11.8 0.0 2.9 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_33 PF13592.1 EIE90430.1 - 0.00015 21.2 0.2 0.00046 19.6 0.0 1.9 2 0 0 2 2 1 1 Winged helix-turn helix HTH_24 PF13412.1 EIE90430.1 - 0.00024 20.4 0.6 0.017 14.5 0.1 2.8 3 0 0 3 3 2 1 Winged helix-turn-helix DNA-binding HTH_21 PF13276.1 EIE90430.1 - 0.00048 20.0 0.0 0.0023 17.8 0.0 2.1 2 0 0 2 2 2 1 HTH-like domain LacI PF00356.16 EIE90430.1 - 0.0012 18.3 0.6 1.1 8.8 0.0 2.5 2 0 0 2 2 2 2 Bacterial regulatory proteins, lacI family GerE PF00196.14 EIE90430.1 - 0.0028 16.9 0.2 0.0084 15.4 0.1 1.8 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family TrmB PF01978.14 EIE90430.1 - 0.004 16.8 0.3 0.05 13.3 0.1 2.4 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_AsnC-type PF13404.1 EIE90430.1 - 0.0041 16.6 0.1 0.011 15.1 0.0 1.7 2 0 0 2 2 1 1 AsnC-type helix-turn-helix domain KorB PF08535.5 EIE90430.1 - 0.0057 16.7 0.1 0.015 15.4 0.0 1.7 1 0 0 1 1 1 1 KorB domain HTH_6 PF01418.12 EIE90430.1 - 0.0059 16.3 0.7 0.64 9.7 0.1 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain, rpiR family GntR PF00392.16 EIE90430.1 - 0.0071 15.7 0.1 1.3 8.5 0.0 2.6 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family HTH_3 PF01381.17 EIE90430.1 - 0.013 15.3 0.7 0.2 11.5 0.2 2.2 2 0 0 2 2 2 0 Helix-turn-helix Trp_repressor PF01371.14 EIE90430.1 - 0.013 15.4 0.3 0.039 13.8 0.1 1.9 2 0 0 2 2 2 0 Trp repressor protein Phage_terminase PF10668.4 EIE90430.1 - 0.014 15.2 0.1 0.014 15.2 0.1 2.0 2 0 0 2 2 1 0 Phage terminase small subunit HTH_40 PF14493.1 EIE90430.1 - 0.03 14.5 0.0 0.063 13.4 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma54_DBD PF04552.8 EIE90430.1 - 0.03 13.8 1.5 0.21 11.1 0.1 2.6 3 0 0 3 3 2 0 Sigma-54, DNA binding domain Fe_dep_repress PF01325.14 EIE90430.1 - 0.037 13.9 2.2 1.6 8.7 0.1 3.3 3 0 0 3 3 3 0 Iron dependent repressor, N-terminal DNA binding domain HTH_10 PF04967.7 EIE90430.1 - 0.085 12.4 0.1 1.5 8.4 0.0 2.3 2 0 0 2 2 2 0 HTH DNA binding domain HTH_5 PF01022.15 EIE90430.1 - 0.094 12.3 0.1 1.3 8.7 0.0 2.4 2 1 0 2 2 2 0 Bacterial regulatory protein, arsR family DUF977 PF06163.6 EIE90430.1 - 0.12 12.1 0.8 4.9 6.9 0.0 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF977) Sigma70_r4_2 PF08281.7 EIE90430.1 - 0.12 11.8 0.5 1.5 8.3 0.1 2.3 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_17 PF12728.2 EIE90430.1 - 0.12 12.6 0.1 6.1 7.1 0.0 3.2 3 0 0 3 3 2 0 Helix-turn-helix domain RVT_1 PF00078.22 EIE90431.1 - 2.4e-14 53.2 0.0 2.8e-14 52.9 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EIE90432.1 - 5.1e-18 65.3 0.0 1.7e-17 63.6 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 EIE90432.1 - 5.4e-14 52.0 0.7 1.5e-13 50.6 0.5 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE90432.1 - 5.4e-07 29.1 1.3 2.8e-06 26.9 0.8 2.2 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 EIE90432.1 - 0.01 15.4 0.7 0.027 14.1 0.5 1.7 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain YcgR_2 PF12945.2 EIE90432.1 - 0.06 13.2 0.0 0.2 11.5 0.0 1.9 1 0 0 1 1 1 0 Flagellar protein YcgR HTH_Tnp_Tc3_2 PF01498.13 EIE90433.1 - 3.4e-05 23.8 0.2 4.4e-05 23.4 0.1 1.2 1 0 0 1 1 1 1 Transposase Galactosyl_T PF01762.16 EIE90433.1 - 0.13 11.8 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 Galactosyltransferase DDE_3 PF13358.1 EIE90434.1 - 2.1e-21 76.2 0.5 2.8e-21 75.7 0.3 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE90435.1 - 4.2e-07 29.9 0.4 7.3e-06 25.9 0.1 2.7 2 1 0 2 2 2 1 Transposase DDE_3 PF13358.1 EIE90435.1 - 0.0019 17.9 0.9 0.11 12.1 0.6 2.2 1 1 0 1 1 1 1 DDE superfamily endonuclease Helicase_IV_N PF12462.3 EIE90436.1 - 0.064 12.9 3.7 0.12 11.9 2.6 1.4 1 0 0 1 1 1 0 DNA helicase IV / RNA helicase N terminal PHD_3 PF13922.1 EIE90436.1 - 2.6 8.3 4.4 39 4.5 2.4 2.3 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx HTH_Tnp_Tc3_2 PF01498.13 EIE90437.1 - 3.4e-05 23.8 0.2 4.4e-05 23.4 0.1 1.2 1 0 0 1 1 1 1 Transposase Galactosyl_T PF01762.16 EIE90437.1 - 0.13 11.8 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 Galactosyltransferase HTH_Tnp_4 PF13613.1 EIE90438.1 - 0.0064 15.9 0.0 0.018 14.5 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix of DDE superfamily endonuclease HTH_23 PF13384.1 EIE90438.1 - 0.022 14.4 0.0 0.056 13.1 0.0 1.7 1 0 0 1 1 1 0 Homeodomain-like domain RecX PF02631.11 EIE90438.1 - 0.046 13.9 0.0 0.075 13.2 0.0 1.3 1 0 0 1 1 1 0 RecX family DUF2828 PF11443.3 EIE90438.1 - 0.099 10.8 0.0 0.099 10.8 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Flavi_capsid PF01003.14 EIE90440.1 - 0.026 14.0 0.0 0.04 13.4 0.0 1.4 1 0 0 1 1 1 0 Flavivirus capsid protein C DDE_3 PF13358.1 EIE90443.1 - 1.6e-17 63.5 0.4 8.9e-17 61.1 0.0 2.3 3 0 0 3 3 3 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE90443.1 - 1.8e-11 43.9 0.6 4.1e-11 42.7 0.4 1.7 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.1 EIE90443.1 - 0.02 15.6 0.1 0.88 10.4 0.0 2.9 3 0 0 3 3 3 0 Homeodomain-like domain HTH_29 PF13551.1 EIE90443.1 - 0.04 14.0 0.0 0.11 12.6 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn helix DDE_Tnp_IS1595 PF12762.2 EIE90446.1 - 1e-22 80.5 0.4 1.8e-22 79.7 0.3 1.4 1 0 0 1 1 1 1 ISXO2-like transposase domain rve PF00665.21 EIE90448.1 - 1.6e-26 92.7 0.0 4e-26 91.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 EIE90448.1 - 1.6e-05 24.3 0.0 5.5e-05 22.6 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.5 EIE90448.1 - 0.0015 17.9 0.0 0.004 16.5 0.0 1.8 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger RVT_1 PF00078.22 EIE90449.1 - 1.7e-30 105.9 0.2 3e-30 105.1 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease PF09668.5 EIE90449.1 - 7.8e-10 38.3 0.0 1.4e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 EIE90449.1 - 1.6e-07 31.7 0.0 3.8e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 EIE90449.1 - 3.9e-05 23.4 0.0 0.00018 21.3 0.0 2.2 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EIE90449.1 - 0.00028 20.6 0.0 0.00065 19.4 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 EIE90449.1 - 0.00093 19.1 0.0 0.0019 18.1 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Spuma_A9PTase PF03539.9 EIE90449.1 - 0.002 18.0 0.4 0.0068 16.3 0.0 2.0 2 0 0 2 2 2 1 Spumavirus aspartic protease (A9) Daxx PF03344.10 EIE90449.1 - 0.027 12.9 7.9 0.039 12.4 5.5 1.1 1 0 0 1 1 1 0 Daxx Family DUF1759 PF03564.10 EIE90450.1 - 0.0006 19.6 0.4 0.0006 19.6 0.3 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1759) 7TM_GPCR_Srx PF10328.4 EIE90452.1 - 0.075 12.1 1.7 0.087 11.9 1.2 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx DDE_Tnp_IS1595 PF12762.2 EIE90454.1 - 1.3e-14 54.2 0.0 4.3e-09 36.3 0.0 2.7 1 1 1 2 2 2 2 ISXO2-like transposase domain DDE_3 PF13358.1 EIE90455.1 - 3.2e-18 65.8 0.0 4.7e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE90455.1 - 7.3e-10 38.7 0.4 3.2e-09 36.7 0.3 2.2 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.1 EIE90455.1 - 0.00011 21.6 0.1 0.00038 20.0 0.0 1.9 2 0 0 2 2 2 1 Homeodomain-like domain DDE_Tnp_ISAZ013 PF07592.6 EIE90455.1 - 0.0076 15.0 0.1 0.04 12.6 0.0 1.9 2 0 0 2 2 2 1 Rhodopirellula transposase DDE domain rve PF00665.21 EIE90455.1 - 0.046 13.8 0.0 0.14 12.2 0.0 1.8 2 0 0 2 2 2 0 Integrase core domain Sigma70_r4 PF04545.11 EIE90455.1 - 0.12 11.6 0.1 0.3 10.4 0.1 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_38 PF13936.1 EIE90455.1 - 0.17 11.4 0.7 0.36 10.4 0.5 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain DDE_3 PF13358.1 EIE90456.1 - 4.1e-30 104.4 0.0 7.5e-30 103.6 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 EIE90456.1 - 5.9e-06 26.3 0.0 1.4e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.1 EIE90456.1 - 1.5e-05 24.9 0.6 3.4e-05 23.7 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_psq PF05225.11 EIE90456.1 - 1.6e-05 24.3 0.0 3.6e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_32 PF13565.1 EIE90456.1 - 5.7e-05 23.8 0.0 0.00027 21.6 0.0 2.2 3 0 0 3 3 2 1 Homeodomain-like domain HTH_23 PF13384.1 EIE90456.1 - 0.00026 20.5 0.0 0.00069 19.1 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_7 PF02796.10 EIE90456.1 - 0.0034 17.2 0.0 0.089 12.6 0.0 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase DDE_1 PF03184.14 EIE90456.1 - 0.0047 16.1 2.1 0.014 14.5 0.1 2.4 2 1 0 2 2 2 1 DDE superfamily endonuclease DUF1804 PF08822.6 EIE90456.1 - 0.0049 16.6 0.1 0.012 15.3 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1804) HTH_1 PF00126.22 EIE90456.1 - 0.0064 16.2 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family CENP-B_N PF04218.8 EIE90456.1 - 0.032 13.6 0.0 0.11 11.9 0.0 2.0 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_38 PF13936.1 EIE90456.1 - 0.045 13.3 0.0 0.35 10.4 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain rve PF00665.21 EIE90456.1 - 0.046 13.8 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain Sigma70_r4_2 PF08281.7 EIE90456.1 - 0.049 13.0 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 TrmB PF01978.14 EIE90456.1 - 0.11 12.2 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DDE_3 PF13358.1 EIE90457.1 - 7.7e-20 71.1 0.0 1.3e-19 70.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_23 PF13384.1 EIE90457.1 - 4.7e-05 22.8 0.0 0.0022 17.5 0.0 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.1 EIE90457.1 - 0.00021 21.2 0.0 0.029 14.3 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.1 EIE90457.1 - 0.0029 16.7 0.0 0.0062 15.6 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 Sigma70_r4_2 PF08281.7 EIE90457.1 - 0.01 15.3 0.0 0.024 14.1 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_17 PF12728.2 EIE90457.1 - 0.031 14.5 0.4 0.35 11.1 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain GerE PF00196.14 EIE90457.1 - 0.058 12.7 0.0 0.097 11.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family HTH_Tnp_4 PF13613.1 EIE90457.1 - 0.085 12.4 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease rve PF00665.21 EIE90458.1 - 5.9e-24 84.4 0.0 2.2e-23 82.6 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 EIE90458.1 - 1.3e-13 50.7 0.1 4.5e-13 49.0 0.0 1.9 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE90458.1 - 1.3e-08 34.3 0.7 1.2e-07 31.2 0.1 2.8 3 0 0 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.12 EIE90458.1 - 8.1e-06 25.8 3.3 1.8e-05 24.7 0.1 3.1 2 0 0 2 2 2 1 Retrotransposon gag protein rve_3 PF13683.1 EIE90458.1 - 0.0057 16.1 0.0 0.025 14.1 0.0 2.2 1 0 0 1 1 1 1 Integrase core domain DDE_3 PF13358.1 EIE90459.1 - 5.5e-21 74.8 0.4 7.6e-21 74.3 0.3 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF3153 PF11353.3 EIE90460.1 - 0.14 11.5 1.2 0.21 11.0 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3153) DDE_Tnp_4 PF13359.1 EIE90461.1 - 4.8e-11 42.5 0.0 2.2e-09 37.0 0.0 2.1 1 1 1 2 2 2 2 DDE superfamily endonuclease MtrG PF04210.8 EIE90461.1 - 0.099 12.3 0.1 0.4 10.4 0.0 2.0 2 1 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G F_actin_bind PF08919.5 EIE90462.1 - 0.027 14.1 0.7 0.034 13.8 0.5 1.3 1 0 0 1 1 1 0 F-actin binding NOD PF06816.8 EIE90462.1 - 0.036 13.1 0.5 0.058 12.4 0.3 1.3 1 0 0 1 1 1 0 NOTCH protein DEC-1_N PF04625.8 EIE90462.1 - 0.04 12.5 0.7 0.048 12.3 0.5 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region HAUS-augmin3 PF14932.1 EIE90462.1 - 0.099 11.8 5.1 0.13 11.4 3.5 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF262 PF03235.9 EIE90462.1 - 0.15 12.0 1.1 0.17 11.8 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF262 MULE PF10551.4 EIE90463.1 - 2.3e-07 30.8 0.0 6e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 EIE90463.1 - 1.7e-06 26.8 0.4 3e-06 26.0 0.3 1.3 1 0 0 1 1 1 1 Transposase, Mutator family SWIM PF04434.12 EIE90463.1 - 1.4e-05 24.4 1.6 3.2e-05 23.2 1.1 1.6 1 0 0 1 1 1 1 SWIM zinc finger FAR1 PF03101.10 EIE90463.1 - 0.00012 22.5 2.7 0.00014 22.3 0.6 2.1 2 0 0 2 2 2 1 FAR1 DNA-binding domain DDE_Tnp_IS240 PF13610.1 EIE90463.1 - 0.001 19.0 0.0 1.5 8.7 0.0 2.5 2 0 0 2 2 2 2 DDE domain zf-CCCH_2 PF14608.1 EIE90465.1 - 2.2e-15 55.9 58.5 9.2e-07 28.6 2.7 5.5 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type DUF3488 PF11992.3 EIE90465.1 - 0.21 10.1 1.2 0.31 9.6 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3488) Peptidase_S9 PF00326.16 EIE90466.1 - 1.3e-45 155.1 0.0 2.5e-45 154.3 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EIE90466.1 - 4.6e-11 42.6 0.0 7.5e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EIE90466.1 - 2.2e-07 30.4 0.0 4.8e-07 29.2 0.0 1.6 1 1 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.6 EIE90466.1 - 4e-06 26.6 0.0 8.4e-05 22.3 0.0 2.4 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.8 EIE90466.1 - 8.3e-05 22.2 0.0 0.00063 19.3 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 EIE90466.1 - 0.00024 20.7 0.0 0.0026 17.3 0.0 2.5 4 0 0 4 4 4 1 alpha/beta hydrolase fold FSH1 PF03959.8 EIE90466.1 - 0.00043 19.8 0.0 0.00078 18.9 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EIE90466.1 - 0.0024 17.7 0.0 0.0042 16.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 EIE90466.1 - 0.0042 15.6 0.1 0.063 11.7 0.1 2.2 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) DUF829 PF05705.9 EIE90466.1 - 0.0082 15.8 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Abhydrolase_4 PF08386.5 EIE90466.1 - 0.014 15.2 0.0 0.029 14.2 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Glycogen_syn PF05693.8 EIE90467.1 - 0 1076.5 0.0 0 1076.2 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 EIE90467.1 - 6.9e-08 32.1 0.0 3.9e-05 23.1 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 EIE90467.1 - 7.3e-07 28.9 0.1 8.6e-06 25.4 0.0 2.2 2 0 0 2 2 2 1 Starch synthase catalytic domain Glyco_trans_4_4 PF13579.1 EIE90467.1 - 0.00024 21.2 0.0 0.00046 20.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain cobW PF02492.14 EIE90468.1 - 2e-25 89.2 0.1 2.5e-25 88.9 0.1 1.0 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain Beta_elim_lyase PF01212.16 EIE90469.1 - 1e-73 248.0 0.1 1.3e-73 247.6 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 EIE90469.1 - 0.0004 18.7 0.0 0.00082 17.7 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EIE90469.1 - 0.0011 18.1 0.0 0.0042 16.1 0.0 1.9 3 0 0 3 3 3 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 EIE90469.1 - 0.0015 17.5 0.0 0.0034 16.3 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II Mannosyl_trans3 PF11051.3 EIE90470.1 - 1e-48 166.0 0.1 2.5e-48 164.7 0.0 1.7 1 0 0 1 1 1 1 Mannosyltransferase putative PQ-loop PF04193.9 EIE90470.1 - 4.7e-36 122.1 9.0 1.7e-20 72.3 2.8 2.5 2 0 0 2 2 2 2 PQ loop repeat DUF4446 PF14584.1 EIE90470.1 - 0.16 11.7 5.0 2 8.2 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) Glyco_transf_15 PF01793.11 EIE90471.1 - 1.6e-52 178.5 9.2 2e-52 178.1 6.4 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Corona_M PF01635.13 EIE90471.1 - 0.11 11.3 0.1 0.19 10.6 0.1 1.3 1 0 0 1 1 1 0 Coronavirus M matrix/glycoprotein E1-E2_ATPase PF00122.15 EIE90472.1 - 1.5e-58 197.5 9.4 1.5e-58 197.5 6.5 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 EIE90472.1 - 4.3e-26 92.6 0.1 2.2e-25 90.3 0.0 2.2 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EIE90472.1 - 3.2e-14 53.5 0.0 7.3e-14 52.3 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EIE90472.1 - 0.0009 18.8 0.4 0.0022 17.6 0.1 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase CUE PF02845.11 EIE90473.1 - 1.3e-07 30.9 0.0 2.2e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 CUE domain UBA PF00627.26 EIE90473.1 - 0.0013 18.4 0.0 0.0024 17.6 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain Myosin_TH1 PF06017.8 EIE90473.1 - 0.077 12.2 0.1 0.096 11.9 0.1 1.1 1 0 0 1 1 1 0 Myosin tail RNA_pol_Rpb5_N PF03871.9 EIE90473.1 - 0.083 13.3 0.2 0.12 12.8 0.1 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb5, N-terminal domain ATP-synt_G PF04718.10 EIE90474.1 - 4.2e-22 78.7 0.3 6.2e-22 78.2 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial ATP synthase g subunit Arrestin_C PF02752.17 EIE90476.1 - 5e-08 33.1 0.2 1.2e-06 28.6 0.0 2.4 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain WD-3 PF09765.4 EIE90477.1 - 1.6e-30 106.4 2.2 2e-30 106.0 1.5 1.0 1 0 0 1 1 1 1 WD-repeat region FANCL_C PF11793.3 EIE90477.1 - 0.0028 17.5 0.1 0.0054 16.6 0.0 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain RWD PF05773.17 EIE90477.1 - 0.034 14.0 2.0 0.058 13.2 1.0 1.8 2 1 0 2 2 2 0 RWD domain UQ_con PF00179.21 EIE90477.1 - 0.044 13.2 0.1 0.11 11.8 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-conjugating enzyme Myb_DNA-binding PF00249.26 EIE90478.1 - 4.5e-05 23.4 0.8 0.00015 21.7 0.0 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EIE90478.1 - 0.019 15.0 0.0 0.019 15.0 0.0 3.0 3 0 0 3 3 3 0 Myb-like DNA-binding domain Ras PF00071.17 EIE90479.1 - 5.4e-50 168.9 0.0 6.4e-50 168.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIE90479.1 - 1.4e-18 67.5 0.0 2e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIE90479.1 - 2.8e-08 33.2 0.0 4.6e-08 32.5 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EIE90479.1 - 4.9e-07 29.3 0.1 3.6e-06 26.5 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EIE90479.1 - 0.00016 20.8 0.0 0.00019 20.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EIE90479.1 - 0.0031 17.4 0.0 0.0045 16.9 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 EIE90479.1 - 0.015 14.8 0.5 0.18 11.2 0.3 2.5 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 EIE90479.1 - 0.018 14.2 0.0 0.029 13.6 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.22 EIE90479.1 - 0.11 12.8 0.0 0.15 12.3 0.0 1.5 1 1 0 1 1 1 0 ABC transporter Ribosomal_60s PF00428.14 EIE90480.1 - 2.3e-26 92.0 8.8 2.8e-26 91.7 6.1 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Sugar_tr PF00083.19 EIE90481.1 - 8.3e-80 268.5 38.9 2e-46 158.4 2.8 3.1 2 1 1 3 3 3 3 Sugar (and other) transporter MFS_1 PF07690.11 EIE90481.1 - 3.8e-14 52.1 33.8 3.4e-11 42.4 3.0 3.1 2 1 1 3 3 3 2 Major Facilitator Superfamily PSI PF01437.20 EIE90481.1 - 0.001 19.1 4.2 0.0017 18.4 2.9 1.3 1 0 0 1 1 1 1 Plexin repeat PAT1 PF09770.4 EIE90483.1 - 0.41 8.8 39.2 0.51 8.5 27.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF1980 PF09323.5 EIE90483.1 - 0.46 10.1 10.2 0.042 13.6 2.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Coiled-coil_56 PF09813.4 EIE90483.1 - 1.2 9.1 9.2 6.1 6.8 0.1 2.4 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 56 DUF2547 PF10818.3 EIE90483.1 - 1.4 9.6 22.4 2.6 8.7 2.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2547) COX16 PF14138.1 EIE90483.1 - 4.6 7.4 6.8 5.4 7.2 0.0 2.3 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 RNA_pol_Rpb2_6 PF00562.23 EIE90484.1 - 6.4e-116 387.2 1.6 8.5e-116 386.8 1.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EIE90484.1 - 2.1e-30 105.1 0.0 3.1e-30 104.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.11 EIE90484.1 - 5.4e-24 83.7 0.0 1.3e-23 82.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.7 EIE90484.1 - 3.6e-23 81.2 0.0 6.9e-23 80.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.15 EIE90484.1 - 5.8e-21 74.5 0.0 1.3e-20 73.4 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.9 EIE90484.1 - 5.8e-20 71.5 0.0 1e-19 70.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_5 PF04567.12 EIE90484.1 - 0.00074 19.4 0.0 0.0017 18.2 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Polysacc_deac_1 PF01522.16 EIE90485.1 - 4.5e-24 84.4 0.0 7.4e-24 83.7 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 EIE90485.1 - 4e-05 22.6 0.0 7.5e-05 21.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 DUF3580 PF12117.3 EIE90485.1 - 0.064 13.2 3.9 4.2 7.3 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3580) Gp_dh_C PF02800.15 EIE90486.1 - 2e-74 248.2 0.0 2.8e-74 247.7 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 EIE90486.1 - 2.9e-59 199.3 0.1 6.6e-59 198.2 0.1 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 EIE90486.1 - 0.08 12.8 0.3 0.41 10.5 0.0 2.3 3 0 0 3 3 3 0 Dihydrodipicolinate reductase, N-terminus DUF3808 PF10300.4 EIE90487.1 - 9.5e-28 96.9 0.1 9.5e-28 96.9 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3808) TPR_12 PF13424.1 EIE90487.1 - 1.4e-08 34.5 1.2 9.3e-06 25.4 0.0 3.7 3 1 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 EIE90487.1 - 0.00022 20.7 0.3 0.0028 17.3 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 EIE90487.1 - 0.0013 18.3 0.6 0.036 13.6 0.0 2.6 2 1 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 EIE90487.1 - 0.0035 16.8 0.0 0.024 14.2 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 EIE90487.1 - 0.011 15.6 5.6 0.035 14.0 0.0 3.8 4 1 0 4 4 4 0 Tetratricopeptide repeat RRP7 PF12923.2 EIE90488.1 - 8.4e-37 126.1 13.3 8.4e-37 126.1 9.2 1.8 3 0 0 3 3 3 1 Ribosomal RNA-processing protein 7 (RRP7) Enolase_C PF00113.17 EIE90488.1 - 0.015 14.2 0.0 0.076 11.9 0.0 2.0 2 0 0 2 2 2 0 Enolase, C-terminal TIM barrel domain RRM_1 PF00076.17 EIE90488.1 - 0.039 13.5 0.0 0.19 11.3 0.0 2.2 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4364 PF14277.1 EIE90488.1 - 0.06 12.9 1.1 0.15 11.6 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4364) Parathyroid PF01279.12 EIE90488.1 - 4.2 8.0 11.7 1.7 9.2 1.8 2.7 2 1 1 3 3 3 0 Parathyroid hormone family DnaJ-X PF14308.1 EIE90489.1 - 9.1e-42 142.6 2.9 1.5e-23 83.1 0.1 2.6 2 1 1 3 3 3 2 X-domain of DnaJ-containing DnaJ PF00226.26 EIE90489.1 - 1.2e-14 53.7 0.6 1.2e-14 53.7 0.4 2.1 2 0 0 2 2 2 1 DnaJ domain PRP1_N PF06424.7 EIE90489.1 - 0.39 11.0 2.9 0.21 11.9 0.4 1.7 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal GCOM2 PF15328.1 EIE90490.1 - 0.062 13.0 15.6 0.71 9.5 10.8 2.4 1 1 0 1 1 1 0 Putative GRINL1B complex locus protein 2 TFIIA PF03153.8 EIE90490.1 - 0.19 11.5 12.3 0.24 11.2 8.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit eIF-3c_N PF05470.7 EIE90490.1 - 0.23 9.5 8.4 0.24 9.4 5.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Kin17_mid PF10357.4 EIE90491.1 - 5.3e-45 152.1 0.4 5.3e-45 152.1 0.3 2.3 3 0 0 3 3 3 1 Domain of Kin17 curved DNA-binding protein zf-CCHC PF00098.18 EIE90491.1 - 5.6e-12 44.9 15.6 0.00086 19.1 0.9 4.1 3 0 0 3 3 3 3 Zinc knuckle zf-C2H2_jaz PF12171.3 EIE90491.1 - 0.0027 17.8 7.2 0.0027 17.8 5.0 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EIE90491.1 - 0.012 15.7 1.9 0.012 15.7 1.3 3.6 3 1 1 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 EIE90491.1 - 0.015 15.4 5.2 0.015 15.4 3.6 2.7 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-CCHC_4 PF14392.1 EIE90491.1 - 0.029 14.0 2.0 0.029 14.0 1.4 4.2 4 0 0 4 4 4 0 Zinc knuckle zf-CCHC_2 PF13696.1 EIE90491.1 - 0.049 13.1 13.3 0.39 10.2 0.2 3.5 2 1 1 3 3 3 0 Zinc knuckle HTH_Tnp_Tc5 PF03221.11 EIE90495.1 - 0.061 13.1 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain Stork_head PF10264.4 EIE90495.1 - 0.13 12.4 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 Winged helix Storkhead-box1 domain DDE_3 PF13358.1 EIE90496.1 - 1.3e-25 89.8 0.0 1.6e-25 89.6 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.14 EIE90496.1 - 0.0022 17.1 0.6 0.0068 15.5 0.4 1.8 1 1 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE90496.1 - 0.086 12.9 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Integrase core domain DDE_3 PF13358.1 EIE90498.1 - 6.4e-29 100.5 0.1 1.2e-27 96.4 0.1 2.3 1 1 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE90498.1 - 0.00023 21.2 0.0 0.00082 19.4 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain DDE_1 PF03184.14 EIE90498.1 - 0.00043 19.4 0.1 0.0068 15.5 0.0 2.1 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_28 PF13518.1 EIE90498.1 - 0.062 13.3 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.1 EIE90498.1 - 0.067 12.8 0.0 0.4 10.3 0.0 2.1 2 0 0 2 2 2 0 Homeodomain-like domain Myc_N PF01056.13 EIE90500.1 - 0.081 12.0 0.5 0.091 11.9 0.4 1.1 1 0 0 1 1 1 0 Myc amino-terminal region IL7 PF01415.11 EIE90501.1 - 0.026 14.1 0.5 0.7 9.5 0.0 2.2 2 0 0 2 2 2 0 Interleukin 7/9 family MbeB_N PF04837.7 EIE90501.1 - 0.056 13.5 0.2 1.3 9.1 0.0 2.9 2 0 0 2 2 2 0 MbeB-like, N-term conserved region Phosphodiest PF01663.17 EIE90503.1 - 2e-65 221.5 0.5 2.4e-65 221.2 0.3 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EIE90503.1 - 0.00058 19.1 0.1 0.0027 16.9 0.0 2.1 2 1 0 2 2 2 1 Sulfatase FAD-oxidase_C PF02913.14 EIE90505.1 - 2.8e-57 193.8 0.0 4e-57 193.3 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EIE90505.1 - 2.3e-37 127.5 0.4 4.4e-37 126.6 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain Relaxase PF03432.9 EIE90505.1 - 0.0014 18.0 0.1 0.028 13.8 0.0 2.7 3 1 1 4 4 4 1 Relaxase/Mobilisation nuclease domain Macro PF01661.16 EIE90506.1 - 1.8e-37 127.8 0.1 3.2e-37 127.0 0.1 1.4 1 0 0 1 1 1 1 Macro domain FLO_LFY PF01698.11 EIE90507.1 - 0.26 10.1 2.6 0.32 9.8 1.8 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein WD40 PF00400.27 EIE90508.1 - 3.5e-07 29.8 1.4 0.0012 18.6 0.0 4.9 5 1 1 6 6 6 1 WD domain, G-beta repeat PD40 PF07676.7 EIE90508.1 - 0.00063 19.3 0.1 0.32 10.7 0.0 3.5 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat eIF2A PF08662.6 EIE90508.1 - 0.00083 19.1 0.3 0.011 15.5 0.1 2.4 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A DPPIV_N PF00930.16 EIE90508.1 - 0.0057 15.2 2.1 2.5 6.5 0.1 3.2 3 1 1 4 4 4 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region Lactonase PF10282.4 EIE90508.1 - 0.011 14.8 0.0 4.5 6.2 0.0 2.4 3 0 0 3 3 3 0 Lactonase, 7-bladed beta-propeller Aminotran_1_2 PF00155.16 EIE90509.1 - 3.5e-42 144.6 0.0 4.4e-42 144.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EIE90509.1 - 0.0034 16.5 0.0 0.0059 15.7 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase SASRP1 PF15160.1 EIE90510.1 - 0.12 11.6 0.2 0.12 11.6 0.1 1.7 2 0 0 2 2 2 0 Spermatogenesis-associated serine-rich protein 1 UDP-g_GGTase PF06427.6 EIE90511.1 - 3e-56 190.0 0.7 3e-56 190.0 0.5 2.0 3 0 0 3 3 3 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 EIE90511.1 - 3.7e-08 33.0 0.1 9.2e-08 31.7 0.1 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 8 Peptidase_M56 PF05569.6 EIE90512.1 - 0.011 14.7 0.5 0.011 14.7 0.4 1.4 2 0 0 2 2 2 0 BlaR1 peptidase M56 MARVEL PF01284.18 EIE90512.1 - 0.012 15.4 2.6 0.02 14.6 1.8 1.4 1 0 0 1 1 1 0 Membrane-associating domain PgaD PF13994.1 EIE90512.1 - 1.7 8.1 4.3 0.86 9.0 0.0 2.1 2 0 0 2 2 2 0 PgaD-like protein PHD PF00628.24 EIE90513.1 - 5.4e-07 29.2 6.2 1.3e-06 27.9 4.3 1.7 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.1 EIE90513.1 - 0.0067 16.1 1.0 0.0067 16.1 0.7 1.8 1 1 1 2 2 2 1 Prokaryotic RING finger family 1 GDC-P PF02347.11 EIE90513.1 - 0.061 11.9 0.0 0.061 11.9 0.0 1.6 2 0 0 2 2 2 0 Glycine cleavage system P-protein WHIM1 PF15612.1 EIE90513.1 - 0.16 11.9 2.7 0.18 11.7 0.1 2.5 2 0 0 2 2 2 0 WSTF, HB1, Itc1p, MBD9 motif 1 zf-PHD-like PF15446.1 EIE90513.1 - 0.65 9.2 9.5 0.053 12.7 2.6 2.2 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Mucin PF01456.12 EIE90513.1 - 0.7 9.6 11.3 0.2 11.4 2.0 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein zf-C4pol PF14260.1 EIE90513.1 - 2.5 8.1 10.5 1.2 9.2 3.5 2.8 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta NIF PF03031.13 EIE90514.1 - 1.3e-25 89.9 0.4 2.1e-15 56.7 0.1 2.2 1 1 1 2 2 2 2 NLI interacting factor-like phosphatase FMN_dh PF01070.13 EIE90515.1 - 8.6e-106 353.7 0.0 1.2e-105 353.2 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EIE90515.1 - 6.6e-28 96.3 0.0 1.5e-27 95.2 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 EIE90515.1 - 1.3e-06 27.5 0.0 2.1e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 EIE90515.1 - 0.0013 17.7 0.0 0.0022 16.9 0.0 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 EIE90515.1 - 0.091 11.8 0.1 0.14 11.2 0.1 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase DUF3808 PF10300.4 EIE90516.1 - 2.9e-94 316.2 14.1 5.2e-94 315.4 7.1 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF3808) TPR_11 PF13414.1 EIE90516.1 - 0.00098 18.7 3.1 1.4 8.6 0.0 4.5 3 1 1 4 4 4 2 TPR repeat MIT PF04212.13 EIE90516.1 - 0.01 15.6 6.3 2 8.3 0.3 3.6 2 1 0 2 2 2 0 MIT (microtubule interacting and transport) domain AF1Q PF15017.1 EIE90518.1 - 0.056 13.3 1.2 0.083 12.7 0.8 1.3 1 0 0 1 1 1 0 Drug resistance and apoptosis regulator Myc_N PF01056.13 EIE90518.1 - 0.14 11.3 2.8 0.17 11.0 1.9 1.1 1 0 0 1 1 1 0 Myc amino-terminal region PGK PF00162.14 EIE90522.1 - 7.6e-140 465.8 1.2 8.5e-140 465.6 0.9 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase Ras PF00071.17 EIE90523.1 - 1.1e-12 47.6 0.3 5.5e-07 29.1 0.0 2.2 1 1 1 2 2 2 2 Ras family Arf PF00025.16 EIE90523.1 - 0.022 13.9 0.7 1.7 7.8 0.1 2.4 1 1 1 2 2 2 0 ADP-ribosylation factor family GTP_EFTU PF00009.22 EIE90523.1 - 0.04 13.3 0.1 0.05 13.0 0.1 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain FH2 PF02181.18 EIE90525.1 - 6.8e-09 35.0 0.4 8.8e-09 34.7 0.3 1.2 1 0 0 1 1 1 1 Formin Homology 2 Domain Imm24 PF15570.1 EIE90525.1 - 0.008 15.9 0.2 0.0089 15.7 0.2 1.1 1 0 0 1 1 1 1 Immunity protein 24 XFP_N PF09364.5 EIE90525.1 - 0.14 10.6 0.2 0.16 10.4 0.1 1.0 1 0 0 1 1 1 0 XFP N-terminal domain CAP_N PF01213.14 EIE90526.1 - 0.12 11.6 5.1 0.13 11.4 3.5 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.6 EIE90526.1 - 3.9 6.7 16.1 12 5.1 11.5 1.5 1 1 1 2 2 2 0 Mitochondrial fission regulator Drf_GBD PF06371.8 EIE90527.1 - 8.5e-08 31.7 0.7 1.3e-07 31.1 0.5 1.5 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain Imm42 PF15601.1 EIE90528.1 - 0.0027 17.1 0.0 0.0032 16.8 0.0 1.2 1 0 0 1 1 1 1 Immunity protein 42 TMF_DNA_bd PF12329.3 EIE90529.1 - 0.052 13.3 1.1 0.091 12.5 0.7 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.10 EIE90529.1 - 0.057 12.9 0.2 0.11 11.9 0.1 1.4 1 0 0 1 1 1 0 Septum formation initiator CCDC144C PF14915.1 EIE90529.1 - 0.19 10.5 1.6 0.26 10.1 1.1 1.1 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region DUF4140 PF13600.1 EIE90529.1 - 0.3 11.5 1.6 0.43 11.0 1.1 1.3 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Rad9 PF04139.8 EIE90530.1 - 1.3e-30 106.3 1.6 1.6e-30 106.0 1.1 1.1 1 0 0 1 1 1 1 Rad9 Glyoxal_oxid_N PF07250.6 EIE90531.1 - 5.9e-65 218.7 0.0 8.6e-63 211.6 0.0 2.8 2 2 1 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 EIE90531.1 - 5.9e-21 74.3 0.0 1e-20 73.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.1 EIE90531.1 - 0.00011 21.8 0.1 1.1 9.0 0.0 3.2 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.1 EIE90531.1 - 0.00084 19.4 2.0 3.9 7.8 0.0 5.2 5 1 1 6 6 6 1 Kelch motif Kelch_2 PF07646.10 EIE90531.1 - 0.014 15.1 0.0 3.1 7.7 0.0 3.9 5 0 0 5 5 5 0 Kelch motif Prenyltrans PF00432.16 EIE90532.1 - 7.3e-30 102.2 7.3 7.5e-08 31.8 0.0 5.9 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_1 PF13243.1 EIE90532.1 - 7.5e-28 96.7 1.8 1.2e-15 57.4 0.4 6.1 5 2 2 7 7 7 5 Prenyltransferase-like Prenyltrans_2 PF13249.1 EIE90532.1 - 7.1e-27 94.0 0.7 1.9e-15 57.2 0.3 4.6 3 2 2 5 5 5 3 Prenyltransferase-like Pec_lyase PF09492.5 EIE90532.1 - 1.1e-08 34.6 0.4 0.056 12.6 0.0 5.1 3 2 2 5 5 5 3 Pectic acid lyase A2M_comp PF07678.9 EIE90532.1 - 8.7e-05 21.8 0.2 0.0011 18.2 0.0 2.6 2 1 0 3 3 3 1 A-macroglobulin complement component X8 PF07983.8 EIE90532.1 - 0.12 12.9 4.6 0.081 13.4 1.5 2.0 1 1 1 2 2 2 0 X8 domain CdhD PF03599.11 EIE90532.1 - 0.13 10.7 0.3 0.21 10.0 0.2 1.2 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit TGS PF02824.16 EIE90533.1 - 5e-22 77.4 0.1 1e-21 76.5 0.1 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 EIE90533.1 - 1.9e-18 66.4 0.2 5.2e-18 65.0 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EIE90533.1 - 1.6e-11 43.7 0.1 7.3e-11 41.5 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EIE90533.1 - 0.0014 18.4 0.5 0.34 10.7 0.0 2.5 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.22 EIE90533.1 - 0.0033 16.9 0.4 6.4 6.1 0.0 3.5 2 2 1 3 3 3 2 Elongation factor Tu GTP binding domain ArgK PF03308.11 EIE90533.1 - 0.005 15.6 1.7 0.0064 15.3 0.3 1.8 2 0 0 2 2 2 1 ArgK protein Miro PF08477.8 EIE90533.1 - 0.011 16.2 0.1 0.034 14.6 0.0 2.0 2 0 0 2 2 2 0 Miro-like protein Pectinesterase PF01095.14 EIE90534.1 - 1.5e-47 161.6 2.2 2.7e-47 160.7 1.5 1.4 1 1 0 1 1 1 1 Pectinesterase Acetyltransf_2 PF00797.12 EIE90535.1 - 0.059 12.9 0.4 0.086 12.3 0.3 1.2 1 0 0 1 1 1 0 N-acetyltransferase CHIPS PF11434.3 EIE90535.1 - 0.14 11.7 5.2 0.16 11.6 0.9 2.7 2 1 0 2 2 2 0 Chemotaxis-inhibiting protein CHIPS HTH_Tnp_4 PF13613.1 EIE90538.1 - 0.0001 21.7 0.0 0.00017 21.0 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease HTH_23 PF13384.1 EIE90538.1 - 0.00057 19.4 0.1 0.0011 18.5 0.0 1.6 2 0 0 2 2 2 1 Homeodomain-like domain HTH_30 PF13556.1 EIE90538.1 - 0.04 13.5 0.0 0.095 12.3 0.0 1.6 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain RecX PF02631.11 EIE90538.1 - 0.096 12.9 0.1 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 RecX family rve PF00665.21 EIE90539.1 - 1.2e-17 64.0 0.0 7.9e-17 61.4 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 EIE90539.1 - 1.2e-16 60.6 0.1 2.8e-16 59.5 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE90539.1 - 4.5e-09 35.8 0.5 1.1e-08 34.5 0.3 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.1 EIE90539.1 - 2.8e-07 30.9 0.1 7.2e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 EIE90539.1 - 8.8e-07 28.7 0.1 4e-06 26.6 0.0 2.2 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EIE90539.1 - 0.00074 19.2 0.0 0.0017 18.1 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.12 EIE90539.1 - 0.0017 18.3 2.9 0.0049 16.9 0.0 3.3 4 0 0 4 4 4 1 Retrotransposon gag protein Asp_protease PF09668.5 EIE90539.1 - 0.012 15.2 0.2 0.1 12.1 0.0 2.4 2 0 0 2 2 2 0 Aspartyl protease Tudor-knot PF11717.3 EIE90539.1 - 0.019 14.6 0.1 0.081 12.6 0.1 2.1 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain IncA PF04156.9 EIE90539.1 - 2.9 7.4 6.9 7.6 6.0 4.8 1.7 1 0 0 1 1 1 0 IncA protein HTH_Tnp_Tc3_2 PF01498.13 EIE90540.1 - 9.5e-06 25.5 0.2 1.4e-05 25.0 0.1 1.3 1 0 0 1 1 1 1 Transposase DUF4224 PF13986.1 EIE90540.1 - 0.056 12.9 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4224) FliJ PF02050.11 EIE90541.1 - 0.019 15.0 0.9 0.021 14.8 0.6 1.1 1 0 0 1 1 1 0 Flagellar FliJ protein Mvb12 PF09452.5 EIE90541.1 - 0.12 12.5 0.9 0.15 12.2 0.6 1.3 1 1 0 1 1 1 0 ESCRT-I subunit Mvb12 rve PF00665.21 EIE90542.1 - 3.2e-25 88.5 0.0 5.3e-25 87.8 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 EIE90542.1 - 0.00038 19.9 0.0 0.00089 18.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE90543.1 - 6.1e-10 38.8 0.0 1.2e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease PF09668.5 EIE90543.1 - 0.026 14.1 0.0 0.043 13.3 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease AMIN PF11741.3 EIE90543.1 - 0.083 12.8 1.9 4.5 7.3 0.0 3.5 3 1 1 4 4 4 0 AMIN domain DUF1759 PF03564.10 EIE90544.1 - 0.0023 17.7 0.3 0.0023 17.7 0.2 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1759) Med15 PF09606.5 EIE90545.1 - 0.0028 15.9 14.4 0.0037 15.5 9.9 1.3 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal DUF1203 PF06718.6 EIE90545.1 - 0.085 12.6 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1203) Dicty_CTDC PF00526.13 EIE90546.1 - 0.083 12.7 2.0 0.12 12.2 1.4 1.2 1 0 0 1 1 1 0 Dictyostelium (slime mold) repeat Toxin_12 PF07740.7 EIE90546.1 - 1.3 9.6 4.8 1.5 9.4 3.3 1.2 1 0 0 1 1 1 0 Ion channel inhibitory toxin 3HCDH_N PF02737.13 EIE90547.1 - 0.0036 16.9 0.0 0.0054 16.3 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Rep_fac_C PF08542.6 EIE90547.1 - 0.027 14.4 0.0 0.057 13.3 0.0 1.5 1 0 0 1 1 1 0 Replication factor C C-terminal domain DUF4218 PF13960.1 EIE90547.1 - 0.036 13.5 0.0 0.061 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) rve PF00665.21 EIE90548.1 - 1.3e-17 64.0 0.0 3.7e-17 62.5 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE90548.1 - 4.1e-14 52.4 0.9 1e-13 51.1 0.6 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE90548.1 - 1.4e-06 27.8 1.3 5.6e-06 25.9 0.7 2.2 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.1 EIE90548.1 - 3e-05 24.4 0.1 0.00028 21.3 0.0 2.4 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.15 EIE90548.1 - 0.0014 18.5 0.1 0.0048 16.7 0.0 2.0 1 0 0 1 1 1 1 Retroviral aspartyl protease Tudor-knot PF11717.3 EIE90548.1 - 0.019 14.6 0.7 0.054 13.2 0.5 1.8 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain YcgR_2 PF12945.2 EIE90548.1 - 0.033 14.0 0.0 0.42 10.5 0.0 2.5 2 0 0 2 2 2 0 Flagellar protein YcgR gag-asp_proteas PF13975.1 EIE90548.1 - 0.07 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease HTH_Tnp_Tc3_2 PF01498.13 EIE90550.1 - 1.2e-10 41.3 1.8 1.5e-10 40.9 0.2 2.0 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.1 EIE90550.1 - 0.011 15.4 0.1 0.03 13.9 0.1 1.8 1 0 0 1 1 1 0 Homeodomain-like domain HTH_29 PF13551.1 EIE90550.1 - 0.011 15.8 0.3 0.024 14.7 0.0 1.7 2 0 0 2 2 2 0 Winged helix-turn helix HTH_30 PF13556.1 EIE90550.1 - 0.051 13.1 0.0 0.36 10.4 0.0 2.0 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain Leader_Erm PF08253.6 EIE90553.1 - 0.33 10.4 0.3 0.33 10.4 0.2 2.1 2 0 0 2 2 2 0 Erm Leader peptide RVT_1 PF00078.22 EIE90554.1 - 6e-27 94.4 0.0 9.5e-27 93.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EIE90554.1 - 6.1e-15 54.8 0.1 1.6e-14 53.5 0.0 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EIE90554.1 - 9.8e-06 25.6 0.1 3.1e-05 24.0 0.0 1.9 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family FlxA PF14282.1 EIE90554.1 - 0.44 10.5 2.7 0.81 9.6 1.8 1.4 1 0 0 1 1 1 0 FlxA-like protein Serglycin PF04360.7 EIE90554.1 - 1.3 8.7 11.3 0.013 15.2 2.2 1.8 2 0 0 2 2 2 0 Serglycin Exo_endo_phos_2 PF14529.1 EIE90555.1 - 7.3e-15 54.6 0.5 2e-14 53.2 0.0 2.0 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EIE90555.1 - 3.4e-06 27.1 0.1 1e-05 25.5 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family FlxA PF14282.1 EIE90555.1 - 0.16 11.9 2.7 0.32 10.9 1.8 1.5 1 0 0 1 1 1 0 FlxA-like protein X PF00739.14 EIE90555.1 - 1.9 8.3 7.9 3.3 7.6 2.0 2.4 1 1 1 2 2 2 0 Trans-activation protein X RVT_1 PF00078.22 EIE90556.1 - 1.8e-27 96.1 0.0 2.5e-27 95.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Serglycin PF04360.7 EIE90556.1 - 0.007 16.1 3.5 0.007 16.1 2.4 1.9 2 0 0 2 2 2 1 Serglycin RVT_1 PF00078.22 EIE90557.1 - 6.1e-27 94.3 0.0 9.5e-27 93.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EIE90557.1 - 6.2e-15 54.8 0.1 1.6e-14 53.5 0.0 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EIE90557.1 - 1.1e-05 25.5 0.1 3.1e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family FlxA PF14282.1 EIE90557.1 - 0.44 10.5 2.7 0.81 9.6 1.8 1.4 1 0 0 1 1 1 0 FlxA-like protein DDE_3 PF13358.1 EIE90560.1 - 5e-15 55.5 0.1 1.1e-14 54.4 0.1 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE90560.1 - 4.2e-12 45.9 2.9 7.1e-12 45.2 0.6 2.4 3 0 0 3 3 3 1 Transposase HTH_29 PF13551.1 EIE90560.1 - 0.002 18.2 0.8 0.0047 17.0 0.1 1.9 2 0 0 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.1 EIE90560.1 - 0.0076 15.8 0.1 0.023 14.3 0.0 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_30 PF13556.1 EIE90560.1 - 0.063 12.8 0.0 0.19 11.3 0.0 1.7 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain RecX PF02631.11 EIE90560.1 - 0.092 12.9 0.2 0.23 11.6 0.2 1.6 1 0 0 1 1 1 0 RecX family DDE_3 PF13358.1 EIE90561.1 - 5.4e-18 65.1 0.1 1.4e-17 63.8 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE90561.1 - 7e-09 35.6 0.6 3e-08 33.5 0.6 2.0 2 1 0 2 2 2 1 Transposase Retrotrans_gag PF03732.12 EIE90563.1 - 0.00027 20.9 0.5 0.00081 19.4 0.1 2.0 2 0 0 2 2 2 1 Retrotransposon gag protein rve PF00665.21 EIE90565.1 - 8.2e-21 74.3 0.0 2.9e-20 72.5 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 EIE90565.1 - 8.7e-11 41.3 0.4 2.2e-10 40.0 0.3 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain HTH_Tnp_Tc3_2 PF01498.13 EIE90568.1 - 2.7e-17 62.5 2.9 4.1e-17 61.9 0.3 2.2 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 EIE90568.1 - 9.1e-05 22.5 0.6 0.00026 21.1 0.4 1.8 1 1 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.1 EIE90568.1 - 0.00038 21.1 1.6 0.0025 18.5 0.2 2.7 1 1 1 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.1 EIE90568.1 - 0.04 13.5 1.5 1.1 8.9 0.1 3.3 3 1 0 3 3 3 0 Homeodomain-like domain HTH_21 PF13276.1 EIE90568.1 - 0.089 12.8 0.2 0.99 9.4 0.0 2.7 2 1 1 3 3 3 0 HTH-like domain Retrotrans_gag PF03732.12 EIE90569.1 - 7.3e-18 64.4 2.2 8.5e-18 64.2 0.2 2.1 2 0 0 2 2 2 1 Retrotransposon gag protein HTH_Mga PF08280.6 EIE90570.1 - 0.063 13.0 0.4 0.097 12.4 0.3 1.3 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain DUF1825 PF08855.5 EIE90570.1 - 0.11 12.4 0.4 0.13 12.2 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1825) DDE_3 PF13358.1 EIE90571.1 - 1.4e-17 63.8 0.1 2.6e-17 62.9 0.1 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE90571.1 - 5.6e-10 39.1 1.3 8.9e-10 38.5 0.4 1.7 2 0 0 2 2 2 1 Transposase NurA PF09376.5 EIE90572.1 - 0.034 13.6 0.5 0.039 13.4 0.3 1.2 1 0 0 1 1 1 0 NurA domain DUF4119 PF13494.1 EIE90572.1 - 0.15 12.0 2.2 0.29 11.1 0.7 2.0 1 1 1 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF4119) Asp_protease PF09668.5 EIE90573.1 - 3.4e-10 39.5 0.0 5.4e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 EIE90573.1 - 5.3e-08 33.2 0.0 1.5e-07 31.7 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 EIE90573.1 - 3.8e-06 26.7 0.3 1.9e-05 24.4 0.0 2.3 2 1 1 3 3 3 1 Retroviral aspartyl protease RVP_2 PF08284.6 EIE90573.1 - 5.6e-06 26.3 0.0 1.4e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EIE90573.1 - 0.00033 20.4 0.1 0.00062 19.5 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease NOA36 PF06524.7 EIE90573.1 - 2.5 7.2 7.0 5.2 6.2 4.8 1.5 1 0 0 1 1 1 0 NOA36 protein DUF1759 PF03564.10 EIE90574.1 - 0.00021 21.1 0.4 0.00021 21.1 0.3 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1759) DDE_3 PF13358.1 EIE90575.1 - 4.3e-21 75.2 0.4 5.9e-21 74.7 0.3 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_IS1595 PF12762.2 EIE90576.1 - 1.9e-15 57.0 0.1 9.3e-09 35.2 0.0 3.7 3 0 0 3 3 3 2 ISXO2-like transposase domain HTH_Tnp_Tc3_2 PF01498.13 EIE90576.1 - 2e-14 53.3 0.2 3.9e-14 52.4 0.2 1.5 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.1 EIE90576.1 - 2.2e-08 33.9 4.7 2.1e-06 27.5 0.2 3.7 3 1 1 4 4 4 2 DDE superfamily endonuclease HTH_29 PF13551.1 EIE90576.1 - 0.032 14.3 2.0 0.44 10.7 0.0 3.1 3 0 0 3 3 3 0 Winged helix-turn helix Retrotrans_gag PF03732.12 EIE90577.1 - 0.00025 21.0 0.5 0.00065 19.7 0.1 1.9 2 0 0 2 2 2 1 Retrotransposon gag protein rve PF00665.21 EIE90578.1 - 4.4e-20 71.9 0.0 1.4e-19 70.3 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE90578.1 - 2.2e-10 40.2 0.3 4.8e-10 39.1 0.2 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE90578.1 - 1.1e-09 37.8 0.3 2.9e-09 36.4 0.2 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain UCR_hinge PF02320.11 EIE90582.1 - 0.014 15.3 0.2 0.76 9.7 0.0 2.6 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein SURF4 PF02077.10 EIE90583.1 - 1.5e-92 309.7 8.8 1.7e-92 309.5 6.1 1.0 1 0 0 1 1 1 1 SURF4 family MtrE PF04206.7 EIE90583.1 - 0.069 12.1 5.2 1.3 7.9 1.1 2.1 1 1 1 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit E FtsX PF02687.16 EIE90583.1 - 3.5 7.4 20.0 2 8.1 0.6 3.6 2 1 1 3 3 3 0 FtsX-like permease family DUF1129 PF06570.6 EIE90583.1 - 5 6.3 10.1 3.6 6.8 5.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) Aldose_epim PF01263.15 EIE90584.1 - 1.3e-28 100.0 0.0 5.3e-20 71.7 0.0 2.0 1 1 1 2 2 2 2 Aldose 1-epimerase Prok-E2_E PF14462.1 EIE90585.1 - 0.013 15.1 0.0 0.074 12.6 0.0 1.9 1 1 1 2 2 2 0 Prokaryotic E2 family E MRF_C1 PF13887.1 EIE90587.1 - 0.02 13.9 0.1 0.034 13.1 0.1 1.3 1 0 0 1 1 1 0 Myelin gene regulatory factor -C-terminal domain 1 CutA1 PF03091.10 EIE90587.1 - 0.076 12.6 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 CutA1 divalent ion tolerance protein Peptidase_C16 PF01831.12 EIE90588.1 - 0.12 11.8 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Peptidase C16 family MADF_DNA_bdg PF10545.4 EIE90588.1 - 9 6.5 8.8 0.63 10.2 0.1 3.4 4 1 0 4 4 4 0 Alcohol dehydrogenase transcription factor Myb/SANT-like SpvB PF03534.8 EIE90589.1 - 0.046 12.7 0.4 0.051 12.5 0.3 1.0 1 0 0 1 1 1 0 Salmonella virulence plasmid 65kDa B protein DUF3040 PF11239.3 EIE90590.1 - 0.018 15.0 0.1 0.038 14.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) NAP PF00956.13 EIE90591.1 - 6.7e-17 61.4 17.2 2.7e-15 56.1 11.9 2.8 1 1 0 1 1 1 1 Nucleosome assembly protein (NAP) SDA1 PF05285.7 EIE90591.1 - 0.32 10.2 12.1 0.47 9.6 8.4 1.5 1 0 0 1 1 1 0 SDA1 Ribosomal_L18e PF00828.14 EIE90592.1 - 3.7e-25 88.7 0.3 3.7e-25 88.7 0.2 1.6 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 Sulfolobus_pRN PF05584.6 EIE90592.1 - 0.075 13.0 1.3 7.7 6.5 0.0 2.9 3 0 0 3 3 3 0 Sulfolobus plasmid regulatory protein Spindle_Spc25 PF08234.7 EIE90593.1 - 7.1e-12 45.1 0.3 2.5e-11 43.4 0.0 1.9 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 Fmp27_WPPW PF10359.4 EIE90593.1 - 0.0021 16.5 8.5 0.0026 16.2 5.9 1.1 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain MinE PF03776.9 EIE90593.1 - 0.0058 16.1 0.1 0.012 15.0 0.1 1.6 1 0 0 1 1 1 1 Septum formation topological specificity factor MinE AAA_13 PF13166.1 EIE90593.1 - 0.0063 15.0 6.2 0.0073 14.8 4.3 1.1 1 0 0 1 1 1 1 AAA domain DUF2895 PF11444.3 EIE90593.1 - 0.011 14.9 1.7 0.018 14.2 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2895) A2M_comp PF07678.9 EIE90593.1 - 0.033 13.4 0.5 0.044 13.0 0.3 1.2 1 0 0 1 1 1 0 A-macroglobulin complement component DcpS_C PF11969.3 EIE90593.1 - 0.036 14.2 0.3 0.059 13.5 0.2 1.4 1 0 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding COQ7 PF03232.8 EIE90593.1 - 0.1 12.0 2.7 0.088 12.2 1.0 1.5 1 1 0 1 1 1 0 Ubiquinone biosynthesis protein COQ7 DUF342 PF03961.8 EIE90593.1 - 0.12 10.7 8.1 0.15 10.4 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) IncA PF04156.9 EIE90593.1 - 0.17 11.4 8.1 0.26 10.8 5.6 1.4 1 0 0 1 1 1 0 IncA protein Cob_adeno_trans PF01923.13 EIE90593.1 - 0.99 9.1 5.5 0.31 10.8 0.3 2.3 2 1 1 3 3 3 0 Cobalamin adenosyltransferase Exonuc_VII_L PF02601.10 EIE90593.1 - 1.1 8.3 6.5 1.3 8.1 4.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit ATP-synt_B PF00430.13 EIE90593.1 - 1.3 8.8 13.9 2.8 7.7 9.7 1.5 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) Pox_A_type_inc PF04508.7 EIE90593.1 - 6.2 6.8 9.9 0.87 9.5 0.5 3.0 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat RNA_pol_L_2 PF13656.1 EIE90595.1 - 1.7e-30 104.2 0.1 2.6e-30 103.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EIE90595.1 - 5.2e-09 35.1 0.0 8.3e-09 34.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain UQ_con PF00179.21 EIE90596.1 - 1.1e-36 125.3 0.3 2.8e-36 124.0 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme Ank PF00023.25 EIE90596.1 - 0.067 13.0 0.1 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeat UPF0203 PF05254.7 EIE90596.1 - 0.07 12.9 0.4 0.17 11.7 0.3 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0203) NifU_N PF01592.11 EIE90597.1 - 5.1e-53 178.3 0.0 6e-53 178.1 0.0 1.0 1 0 0 1 1 1 1 NifU-like N terminal domain SlyX PF04102.7 EIE90599.1 - 0.014 15.7 1.3 0.014 15.7 0.9 2.3 2 0 0 2 2 2 0 SlyX CorA PF01544.13 EIE90599.1 - 0.017 14.1 2.1 0.021 13.8 1.5 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF904 PF06005.7 EIE90599.1 - 0.44 10.8 11.6 0.038 14.2 3.3 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF904) AATF-Che1 PF13339.1 EIE90599.1 - 0.96 9.6 20.5 6.9 6.8 3.1 2.6 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor G6PD_C PF02781.11 EIE90600.1 - 1.7e-121 404.5 0.0 2.3e-121 404.1 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 EIE90600.1 - 8.5e-39 133.6 0.6 1.6e-38 132.7 0.2 1.7 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, NAD binding domain IPK PF03770.11 EIE90601.1 - 9.3e-07 28.6 0.0 1.3e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase IPK PF03770.11 EIE90602.1 - 5.5e-08 32.6 0.3 5.9e-08 32.5 0.2 1.0 1 0 0 1 1 1 1 Inositol polyphosphate kinase Glyco_hydro_17 PF00332.13 EIE90604.1 - 7.8e-11 41.5 8.4 5.1e-09 35.6 0.6 2.9 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 LRR_4 PF12799.2 EIE90606.1 - 0.065 12.8 22.0 2.9 7.6 0.5 6.9 5 2 3 8 8 8 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EIE90606.1 - 2.6 8.3 16.0 18 5.7 0.0 6.6 10 0 0 10 10 10 0 Leucine Rich repeat LSM PF01423.17 EIE90607.1 - 1.2e-17 63.1 0.2 1.6e-17 62.7 0.2 1.2 1 0 0 1 1 1 1 LSM domain Mu-like_Com PF10122.4 EIE90607.1 - 0.18 10.9 1.6 0.25 10.4 0.2 1.9 2 1 0 2 2 2 0 Mu-like prophage protein Com Sel1 PF08238.7 EIE90608.1 - 6.2e-12 45.7 6.5 0.00034 21.1 0.1 5.3 5 0 0 5 5 5 3 Sel1 repeat zf-MYND PF01753.13 EIE90608.1 - 6.5e-10 38.7 14.1 1.3e-09 37.7 9.8 1.6 1 0 0 1 1 1 1 MYND finger MIT PF04212.13 EIE90608.1 - 0.023 14.5 2.5 6.3 6.7 0.0 4.0 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain Carot_N PF09150.5 EIE90608.1 - 0.085 12.5 0.1 0.25 10.9 0.1 1.8 1 0 0 1 1 1 0 Orange carotenoid protein, N-terminal DUF4164 PF13747.1 EIE90609.1 - 0.031 14.3 1.2 1.6 8.8 0.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) TMF_TATA_bd PF12325.3 EIE90609.1 - 0.065 12.9 0.1 0.12 12.0 0.1 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DivIC PF04977.10 EIE90609.1 - 0.095 12.1 0.6 0.18 11.2 0.4 1.4 1 0 0 1 1 1 0 Septum formation initiator zf-Tim10_DDP PF02953.10 EIE90611.1 - 1.2e-23 82.1 3.3 1.5e-23 81.8 2.3 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Vps54 PF07928.7 EIE90611.1 - 0.016 15.3 0.1 0.021 14.9 0.0 1.3 1 1 0 1 1 1 0 Vps54-like protein SAB PF04382.8 EIE90612.1 - 0.11 12.2 0.2 0.24 11.1 0.1 1.6 1 0 0 1 1 1 0 SAB domain 3HCDH PF00725.17 EIE90613.1 - 0.11 12.8 0.0 0.13 12.7 0.0 1.1 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Pkinase PF00069.20 EIE90614.1 - 2.4e-63 213.7 0.0 2.1e-62 210.6 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE90614.1 - 2e-29 102.4 0.0 3e-29 101.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EIE90614.1 - 8.1e-09 35.8 2.6 1.2e-08 35.3 0.4 2.4 2 0 0 2 2 2 1 Protein kinase C terminal domain PX PF00787.19 EIE90614.1 - 4.1e-07 29.7 4.9 1.1e-06 28.3 3.4 1.8 1 0 0 1 1 1 1 PX domain Kinase-like PF14531.1 EIE90614.1 - 8.4e-05 21.6 0.0 0.00041 19.4 0.0 2.1 2 0 0 2 2 2 1 Kinase-like DUF508 PF04370.7 EIE90614.1 - 0.047 13.3 3.0 0.087 12.4 2.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF508) Kdo PF06293.9 EIE90614.1 - 0.059 12.4 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_S8 PF00082.17 EIE90615.1 - 3.4e-55 187.1 6.9 4.5e-55 186.7 4.8 1.1 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EIE90615.1 - 2.2e-14 53.7 0.1 4.5e-14 52.7 0.1 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 TIR_2 PF13676.1 EIE90615.1 - 0.13 12.4 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 TIR domain Na_sulph_symp PF00939.14 EIE90616.1 - 1.2e-102 344.2 26.4 1.4e-102 344.0 18.3 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region DUF2754 PF10953.3 EIE90616.1 - 0.0066 16.4 0.4 0.0066 16.4 0.3 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF2754) DUF1985 PF09331.6 EIE90616.1 - 0.13 12.0 0.1 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1985) ABC_membrane_2 PF06472.10 EIE90617.1 - 8.1e-88 294.1 1.3 1.2e-87 293.6 0.9 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EIE90617.1 - 3.9e-18 66.0 0.0 1.5e-17 64.1 0.0 2.0 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.14 EIE90617.1 - 0.0011 18.2 0.1 0.27 10.4 0.1 2.5 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EIE90617.1 - 0.0012 18.3 0.6 0.013 15.0 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.1 EIE90617.1 - 0.0036 17.3 0.2 0.021 14.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 EIE90617.1 - 0.0041 17.4 0.0 0.0041 17.4 0.0 2.4 3 1 0 3 3 3 1 AAA domain AAA_16 PF13191.1 EIE90617.1 - 0.0067 16.4 0.0 0.016 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain BRO1 PF03097.13 EIE90618.1 - 1.3e-124 415.7 4.1 1.3e-124 415.7 2.8 2.3 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EIE90618.1 - 1.1e-61 208.3 22.3 1.1e-61 208.3 15.5 2.9 3 1 0 3 3 3 1 ALIX V-shaped domain binding to HIV SpoIIE PF07228.7 EIE90619.1 - 5.9e-15 55.4 0.0 7.2e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 EIE90619.1 - 3.9e-12 46.0 0.1 2.7e-05 23.7 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 EIE90619.1 - 2.1e-10 40.3 0.1 2.9e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C Pkinase PF00069.20 EIE90620.1 - 1.4e-33 116.1 1.8 1.7e-22 79.8 0.0 2.6 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIE90620.1 - 4.2e-19 68.6 0.1 3.1e-14 52.6 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EIE90620.1 - 0.0097 14.8 0.0 0.12 11.3 0.0 2.1 2 0 0 2 2 2 1 Kinase-like CBS PF00571.23 EIE90621.1 - 4e-12 45.7 0.1 5.3e-07 29.3 0.0 2.2 2 0 0 2 2 2 2 CBS domain DUF21 PF01595.15 EIE90622.1 - 1.3e-11 44.1 0.2 1.5e-11 43.9 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function DUF21 Staygreen PF12638.2 EIE90622.1 - 0.071 12.6 0.0 0.077 12.5 0.0 1.2 1 0 0 1 1 1 0 Staygreen protein GRIP PF01465.15 EIE90623.1 - 2.1e-17 62.3 0.5 7.9e-17 60.5 0.4 2.1 1 0 0 1 1 1 1 GRIP domain DUF948 PF06103.6 EIE90623.1 - 0.0082 15.9 9.7 0.0082 15.9 6.8 12.5 4 4 7 12 12 12 4 Bacterial protein of unknown function (DUF948) Reo_sigmaC PF04582.7 EIE90623.1 - 6.8 5.7 62.0 0.21 10.7 4.0 6.4 1 1 4 6 6 6 0 Reovirus sigma C capsid protein Chal_sti_synt_C PF02797.10 EIE90624.1 - 0.077 12.9 0.0 15 5.4 0.0 2.2 1 1 0 2 2 2 0 Chalcone and stilbene synthases, C-terminal domain DDE_3 PF13358.1 EIE90627.1 - 5.7e-06 26.1 0.0 9.3e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease muHD PF10291.4 EIE90629.1 - 2.1e-26 92.6 0.0 4.4e-26 91.6 0.0 1.6 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain Adap_comp_sub PF00928.16 EIE90629.1 - 4.2e-06 26.0 0.2 2.7e-05 23.4 0.2 2.1 1 1 0 1 1 1 1 Adaptor complexes medium subunit family BssS PF13991.1 EIE90629.1 - 0.1 12.3 0.0 0.1 12.3 0.0 2.2 2 0 0 2 2 2 0 BssS protein family Zn_clus PF00172.13 EIE90630.1 - 1.1e-08 34.8 8.7 2.4e-08 33.7 6.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EIE90630.1 - 1e-07 31.0 5.7 2.5e-07 29.8 4.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain GPI-anchored PF10342.4 EIE90633.1 - 2.7 8.5 10.0 2.4 8.7 0.9 3.3 2 1 1 3 3 3 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Xan_ur_permease PF00860.15 EIE90634.1 - 5.9e-25 87.5 21.2 1.8e-23 82.7 14.7 2.1 1 1 0 1 1 1 1 Permease family BenE PF03594.8 EIE90634.1 - 0.00052 18.6 0.3 0.00052 18.6 0.2 1.8 2 0 0 2 2 2 1 Benzoate membrane transport protein Wzy_C PF04932.10 EIE90634.1 - 2.7 7.7 14.3 0.65 9.7 0.4 3.1 3 0 0 3 3 3 0 O-Antigen ligase DUF2834 PF11196.3 EIE90634.1 - 6.4 7.0 10.9 0.093 12.8 1.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2834) FCH PF00611.18 EIE90637.1 - 0.0089 16.1 0.1 0.014 15.5 0.1 1.3 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain Poty_PP PF08440.5 EIE90637.1 - 0.12 11.3 0.1 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Potyviridae polyprotein TEX19 PF15553.1 EIE90638.1 - 0.44 10.4 6.3 0.24 11.2 3.1 1.5 1 1 0 1 1 1 0 Testis-expressed protein 19 Ribosomal_S27 PF01599.14 EIE90639.1 - 5.2e-29 99.8 2.8 1.1e-28 98.8 2.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S27a ubiquitin PF00240.18 EIE90639.1 - 4.7e-19 67.5 0.0 1.1e-18 66.4 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.3 EIE90639.1 - 4.3e-10 39.1 0.0 8.4e-10 38.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like IBR PF01485.16 EIE90639.1 - 0.012 15.5 0.8 0.019 14.8 0.5 1.4 1 0 0 1 1 1 0 IBR domain Ubiquitin_2 PF14560.1 EIE90639.1 - 0.024 14.8 0.0 0.1 12.8 0.0 2.0 2 1 0 2 2 2 0 Ubiquitin-like domain GTP_EFTU PF00009.22 EIE90640.1 - 6.6e-57 191.9 0.0 1.2e-56 191.1 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EIE90640.1 - 9.7e-37 125.1 0.0 2.4e-36 123.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EIE90640.1 - 5e-16 58.5 1.1 5e-16 58.5 0.7 2.4 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EIE90640.1 - 0.00097 19.0 0.3 0.0029 17.5 0.2 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 EIE90640.1 - 0.0013 18.3 0.4 0.0013 18.3 0.3 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 4 Semialdhyde_dhC PF02774.13 EIE90640.1 - 0.12 12.2 0.3 0.32 10.8 0.0 1.8 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain OHCU_decarbox PF09349.5 EIE90641.1 - 1.2e-15 58.1 0.0 1.3e-15 58.0 0.0 1.0 1 0 0 1 1 1 1 OHCU decarboxylase Septin PF00735.13 EIE90642.1 - 1.1e-57 195.2 8.8 6e-55 186.2 6.1 2.8 1 1 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EIE90642.1 - 4.2e-09 36.3 0.0 1.5e-08 34.5 0.0 1.9 1 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EIE90642.1 - 1.9e-07 30.6 0.0 1.7e-05 24.3 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.13 EIE90642.1 - 0.00012 21.6 0.0 0.00073 19.0 0.0 2.0 2 0 0 2 2 2 1 FtsK/SpoIIIE family MobB PF03205.9 EIE90642.1 - 0.00017 21.3 0.2 0.0012 18.5 0.0 2.2 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 EIE90642.1 - 0.0002 21.8 0.6 0.0012 19.3 0.1 2.4 1 1 1 2 2 2 1 Miro-like protein DUF258 PF03193.11 EIE90642.1 - 0.00022 20.4 0.1 0.033 13.3 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ATP_bind_1 PF03029.12 EIE90642.1 - 0.0023 17.5 0.3 0.53 9.7 0.0 2.8 3 0 0 3 3 3 1 Conserved hypothetical ATP binding protein ABC_tran PF00005.22 EIE90642.1 - 0.0034 17.6 0.2 0.008 16.4 0.1 1.9 1 1 0 1 1 1 1 ABC transporter AAA_22 PF13401.1 EIE90642.1 - 0.0048 17.0 0.0 0.012 15.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EIE90642.1 - 0.0057 16.5 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain UPF0079 PF02367.12 EIE90642.1 - 0.0063 16.1 0.0 0.017 14.7 0.0 1.7 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 EIE90642.1 - 0.011 16.0 1.0 2.9 8.2 0.0 2.5 2 1 0 2 2 2 0 AAA domain cobW PF02492.14 EIE90642.1 - 0.011 15.1 0.1 0.046 13.1 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.18 EIE90642.1 - 0.012 15.4 8.5 1.4 8.6 0.3 3.3 2 1 1 3 3 3 0 Dynamin family DUF463 PF04317.7 EIE90642.1 - 0.018 13.6 0.7 0.038 12.5 0.0 1.9 3 0 0 3 3 3 0 YcjX-like family, DUF463 AAA_24 PF13479.1 EIE90642.1 - 0.022 14.3 0.0 0.046 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EIE90642.1 - 0.032 14.2 0.0 0.083 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Pox_A32 PF04665.7 EIE90642.1 - 0.036 13.3 0.0 0.089 12.0 0.0 1.6 1 0 0 1 1 1 0 Poxvirus A32 protein PRK PF00485.13 EIE90642.1 - 0.039 13.5 0.1 0.11 12.0 0.0 1.7 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family DUF3987 PF13148.1 EIE90642.1 - 0.052 12.1 0.0 0.052 12.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) PduV-EutP PF10662.4 EIE90642.1 - 0.066 12.7 0.3 1.4 8.3 0.0 2.5 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.1 EIE90642.1 - 0.087 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EIE90642.1 - 0.1 12.2 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 NACHT domain DUF3970 PF13113.1 EIE90642.1 - 0.11 12.2 1.7 0.66 9.7 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3970) AAA_10 PF12846.2 EIE90642.1 - 0.11 11.8 0.3 0.7 9.2 0.0 2.0 2 0 0 2 2 2 0 AAA-like domain DUF4375 PF14300.1 EIE90642.1 - 0.17 11.8 3.1 0.48 10.4 2.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4375) Cyclin PF08613.6 EIE90643.1 - 2.8e-22 79.7 0.1 6.5e-22 78.5 0.1 1.5 1 0 0 1 1 1 1 Cyclin SOCS PF12610.3 EIE90643.1 - 0.18 12.1 0.9 13 6.1 0.1 2.4 2 0 0 2 2 2 0 Suppressor of cytokine signalling Peptidase_M17 PF00883.16 EIE90644.1 - 1.2e-116 389.0 0.0 1.6e-116 388.5 0.0 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.12 EIE90644.1 - 4.2e-13 49.1 0.5 8e-13 48.2 0.4 1.4 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain DUF3336 PF11815.3 EIE90645.1 - 1.3e-19 70.1 0.0 8.9e-19 67.4 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EIE90645.1 - 7.4e-18 65.2 0.0 1e-17 64.7 0.0 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase DUF3020 PF11223.3 EIE90646.1 - 1.7e-20 73.1 10.5 1.7e-20 73.1 7.3 3.1 4 0 0 4 4 4 1 Protein of unknown function (DUF3020) DUF2881 PF11087.3 EIE90647.1 - 0.57 9.7 5.5 0.75 9.3 3.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2881) Chorein_N PF12624.2 EIE90648.1 - 6e-14 51.5 3.5 7.4e-14 51.3 0.7 2.5 2 0 0 2 2 2 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG2_CAD PF13329.1 EIE90648.1 - 1.7e-12 47.2 1.0 1.7e-12 47.2 0.7 2.9 3 0 0 3 3 3 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.6 EIE90648.1 - 1.4e-11 44.3 0.0 5.5e-11 42.4 0.0 1.9 2 0 0 2 2 2 1 ATG C terminal domain Xpo1 PF08389.7 EIE90649.1 - 0.2 11.5 6.1 0.21 11.4 0.1 4.0 3 2 2 5 5 5 0 Exportin 1-like protein Ank_4 PF13637.1 EIE90650.1 - 1.1e-15 57.6 0.0 2e-09 37.6 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EIE90650.1 - 5.7e-12 45.8 0.0 1.1e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EIE90650.1 - 1.1e-07 31.2 0.0 3.2e-05 23.5 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 EIE90650.1 - 2.2e-06 27.7 0.0 8.1e-06 25.9 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) zf-NADH-PPase PF09297.6 EIE90650.1 - 3e-06 26.6 3.3 6.7e-06 25.5 2.3 1.6 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain Ank_3 PF13606.1 EIE90650.1 - 4e-06 26.5 0.0 6.5e-05 22.7 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat NUDIX-like PF09296.6 EIE90650.1 - 6e-06 26.5 0.0 1.1e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain EF-hand_1 PF00036.27 EIE90651.1 - 5.8e-24 81.5 6.8 2.7e-06 26.2 0.0 6.0 5 1 0 5 5 5 4 EF hand EF-hand_6 PF13405.1 EIE90651.1 - 2.2e-22 76.8 5.5 1.2e-05 24.8 0.0 5.1 5 0 0 5 5 5 4 EF-hand domain EF-hand_7 PF13499.1 EIE90651.1 - 3.5e-22 78.2 3.4 6.2e-09 35.8 0.0 3.3 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 EIE90651.1 - 3.9e-18 63.8 4.5 3.6e-06 26.0 0.0 4.7 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 EIE90651.1 - 5.8e-15 54.6 5.7 1.3e-07 31.1 0.0 4.9 3 2 2 5 5 5 4 EF-hand domain pair EF-hand_9 PF14658.1 EIE90651.1 - 0.0099 15.7 0.0 0.53 10.2 0.0 3.1 3 1 1 4 4 4 1 EF-hand domain Toprim_2 PF13155.1 EIE90651.1 - 0.021 15.1 0.3 22 5.4 0.0 3.2 1 1 2 3 3 3 0 Toprim-like Oxysterol_BP PF01237.13 EIE90652.1 - 4.5e-110 367.4 2.6 7.1e-110 366.8 1.8 1.3 1 0 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.1 EIE90652.1 - 4.7e-16 58.6 0.0 1.3e-15 57.2 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EIE90652.1 - 0.013 15.7 0.1 0.093 12.9 0.0 2.5 2 0 0 2 2 2 0 PH domain PH_11 PF15413.1 EIE90652.1 - 0.018 15.2 4.1 0.83 9.9 0.0 3.6 3 1 1 4 4 4 0 Pleckstrin homology domain COX7a PF02238.10 EIE90653.1 - 0.00017 21.2 0.0 0.0002 21.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIa DUF3318 PF11780.3 EIE90653.1 - 0.024 14.1 0.0 0.027 14.0 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3318) Ribosomal_L23eN PF03939.8 EIE90655.1 - 2.7e-19 68.9 10.1 5.7e-19 67.9 7.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.15 EIE90655.1 - 3.2e-19 68.6 2.9 3.2e-19 68.6 2.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L23 Ribosomal_L7Ae PF01248.21 EIE90656.1 - 5.2e-29 99.6 1.2 6.6e-29 99.2 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Adeno_E3A PF05248.7 EIE90656.1 - 0.041 13.9 0.0 0.054 13.5 0.0 1.3 1 0 0 1 1 1 0 Adenovirus E3A FliM PF02154.10 EIE90656.1 - 0.056 13.1 0.0 0.099 12.2 0.0 1.4 1 1 0 1 1 1 0 Flagellar motor switch protein FliM DUF2096 PF09869.4 EIE90656.1 - 0.083 12.7 0.5 0.12 12.2 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2096) Condensin2nSMC PF12422.3 EIE90657.1 - 0.088 12.5 0.3 0.14 11.8 0.2 1.5 1 1 0 1 1 1 0 Condensin II non structural maintenance of chromosomes subunit Stm1_N PF09598.5 EIE90658.1 - 0.047 14.3 0.2 0.076 13.7 0.1 1.5 1 1 0 1 1 1 0 Stm1 Sec63 PF02889.11 EIE90660.1 - 0.098 11.8 0.1 0.15 11.2 0.1 1.5 1 1 0 1 1 1 0 Sec63 Brl domain Sed5p PF11416.3 EIE90660.1 - 0.26 10.7 2.0 0.75 9.2 0.1 2.3 2 0 0 2 2 2 0 Integral membrane protein Sed5p GTP_EFTU_D3 PF03143.12 EIE90661.1 - 3.3e-23 81.7 0.1 4e-23 81.4 0.0 1.0 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain DUF2917 PF11142.3 EIE90661.1 - 0.06 12.5 0.0 1.8 7.8 0.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2917) ERG4_ERG24 PF01222.12 EIE90662.1 - 3.2e-130 434.5 28.6 9.2e-128 426.4 19.8 2.0 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 EIE90662.1 - 0.0038 16.5 0.4 0.0072 15.6 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Aldedh PF00171.17 EIE90663.1 - 3.4e-186 619.1 0.1 3.9e-186 618.9 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EIE90663.1 - 0.0094 14.7 0.1 0.042 12.5 0.1 2.1 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 EIE90663.1 - 0.02 14.1 0.0 1.3 8.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) TPR_11 PF13414.1 EIE90664.1 - 4.6e-34 115.8 22.4 9.2e-19 66.8 0.4 4.8 5 0 0 5 5 5 3 TPR repeat TPR_1 PF00515.23 EIE90664.1 - 1.5e-28 97.1 16.9 8.7e-07 28.2 0.2 6.8 7 0 0 7 7 6 6 Tetratricopeptide repeat TPR_2 PF07719.12 EIE90664.1 - 8.7e-21 72.1 17.1 0.00022 20.8 0.1 6.9 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_12 PF13424.1 EIE90664.1 - 3.6e-15 55.6 15.5 2.5e-10 40.1 0.3 4.8 2 1 5 7 7 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 EIE90664.1 - 2.5e-11 43.9 2.7 0.021 15.5 0.0 4.7 2 2 2 5 5 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 EIE90664.1 - 5.1e-10 38.3 8.0 5.3e-05 22.7 0.0 5.4 6 1 0 6 6 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 EIE90664.1 - 8e-10 38.9 9.9 0.07 13.4 0.0 6.0 3 2 2 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.1 EIE90664.1 - 6.8e-09 34.8 22.9 5.8e-05 22.5 0.2 6.1 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 EIE90664.1 - 8.9e-09 34.8 10.7 0.2 11.9 0.1 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 EIE90664.1 - 2.6e-08 33.7 4.4 0.19 12.4 0.0 6.4 5 3 2 7 7 6 2 Tetratricopeptide repeat Apc3 PF12895.2 EIE90664.1 - 3.7e-08 33.3 14.0 1.7e-06 28.0 2.0 3.8 2 1 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EIE90664.1 - 0.0068 16.2 3.4 0.18 11.6 0.0 4.3 2 1 4 6 6 6 1 Tetratricopeptide repeat TPR_10 PF13374.1 EIE90664.1 - 0.02 14.8 0.3 4.3 7.4 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Peptidase_M74 PF03411.8 EIE90664.1 - 0.034 13.3 0.0 0.051 12.7 0.0 1.3 1 0 0 1 1 1 0 Penicillin-insensitive murein endopeptidase Acetyltransf_11 PF13720.1 EIE90664.1 - 0.16 12.2 0.9 0.79 9.9 0.0 2.5 2 1 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 ASD2 PF08687.6 EIE90664.1 - 0.16 11.2 0.1 0.16 11.2 0.0 2.9 2 1 0 3 3 3 0 Apx/Shroom domain ASD2 PSD4 PF07631.6 EIE90664.1 - 0.22 11.9 3.3 5.8 7.3 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1592) MIT PF04212.13 EIE90664.1 - 0.43 10.4 11.7 2.8 7.9 0.0 4.9 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.1 EIE90664.1 - 0.68 10.5 0.1 0.68 10.5 0.0 6.2 8 0 0 8 8 6 0 Tetratricopeptide repeat FKBP_N PF01346.13 EIE90664.1 - 0.9 9.5 9.5 1.6 8.7 0.4 2.9 2 1 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase V_ATPase_I PF01496.14 EIE90664.1 - 1.1 7.0 3.9 1.4 6.7 2.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TIG PF01833.19 EIE90665.1 - 2.4e-13 49.8 1.0 6.6e-13 48.4 0.1 2.1 2 0 0 2 2 2 1 IPT/TIG domain Ank_2 PF12796.2 EIE90665.1 - 4.3e-11 42.9 0.1 7.7e-11 42.1 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EIE90665.1 - 3.8e-10 39.0 0.5 4.5e-07 29.3 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 EIE90665.1 - 3.8e-08 33.3 0.1 1e-05 25.5 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIE90665.1 - 5.3e-08 32.3 0.2 0.00019 21.3 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EIE90665.1 - 4.2e-06 27.1 0.1 1.5e-05 25.3 0.0 2.0 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Cyclin PF08613.6 EIE90666.1 - 3.7e-16 59.8 1.5 4.5e-16 59.5 1.1 1.1 1 0 0 1 1 1 1 Cyclin LANC_like PF05147.8 EIE90666.1 - 0.011 14.2 0.1 0.013 14.0 0.1 1.1 1 0 0 1 1 1 0 Lanthionine synthetase C-like protein NAC PF01849.13 EIE90666.1 - 0.012 15.1 0.0 0.029 13.8 0.0 1.6 2 0 0 2 2 2 0 NAC domain Cyclin_N PF00134.18 EIE90666.1 - 0.013 15.0 1.7 0.018 14.6 1.2 1.3 1 1 0 1 1 1 0 Cyclin, N-terminal domain EcsB PF05975.7 EIE90666.1 - 1.5 7.1 5.8 3.9 5.8 4.0 1.6 1 1 0 1 1 1 0 Bacterial ABC transporter protein EcsB Flavin_Reduct PF01613.13 EIE90667.1 - 3.9e-39 133.9 0.1 5.3e-39 133.5 0.0 1.2 1 0 0 1 1 1 1 Flavin reductase like domain Yae1_N PF09811.4 EIE90667.1 - 9.6e-06 25.0 0.3 1.8e-05 24.1 0.2 1.5 1 0 0 1 1 1 1 Essential protein Yae1, N terminal TPP_enzyme_N PF02776.13 EIE90668.1 - 4e-52 176.1 0.0 4.7e-51 172.6 0.0 2.4 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EIE90668.1 - 1.9e-37 128.1 0.0 3.2e-37 127.3 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EIE90668.1 - 2.7e-25 88.7 0.0 8.4e-25 87.1 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.1 EIE90668.1 - 0.01 14.7 0.0 0.02 13.8 0.0 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase CO_dh PF02552.11 EIE90668.1 - 0.045 13.2 0.0 0.08 12.5 0.0 1.3 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit Mito_fiss_Elm1 PF06258.6 EIE90669.1 - 2.2e-17 62.9 0.0 2.8e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial fission ELM1 2-Hacid_dh PF00389.25 EIE90669.1 - 0.041 13.3 0.1 0.082 12.3 0.1 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain UNC-50 PF05216.8 EIE90669.1 - 0.066 12.4 0.1 0.093 11.9 0.1 1.2 1 0 0 1 1 1 0 UNC-50 family PHP PF02811.14 EIE90670.1 - 8.7e-15 54.9 0.1 1.4e-14 54.2 0.1 1.4 1 0 0 1 1 1 1 PHP domain Spb1_C PF07780.7 EIE90671.1 - 2.8e-69 232.9 34.5 2.8e-69 232.9 23.9 4.3 2 1 1 3 3 3 1 Spb1 C-terminal domain DUF3381 PF11861.3 EIE90671.1 - 5.4e-47 159.2 15.1 5.4e-47 159.2 10.5 6.5 4 1 2 6 6 6 1 Domain of unknown function (DUF3381) FtsJ PF01728.14 EIE90671.1 - 8e-36 123.7 0.4 1.1e-23 84.2 0.0 2.7 1 1 1 2 2 2 2 FtsJ-like methyltransferase Acyl-CoA_dh_1 PF00441.19 EIE90672.1 - 2.9e-41 141.0 0.0 4.6e-41 140.4 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EIE90672.1 - 1.3e-35 122.4 0.0 2.1e-35 121.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EIE90672.1 - 4.6e-19 67.6 0.0 8.4e-19 66.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EIE90672.1 - 9.9e-14 51.7 0.0 1.7e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain bZIP_1 PF00170.16 EIE90673.1 - 7.5e-10 38.6 19.3 2.2e-09 37.1 9.8 2.5 1 1 1 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.10 EIE90673.1 - 5.1e-06 26.2 26.0 6.7e-06 25.8 7.9 3.0 1 1 2 3 3 3 2 Basic region leucine zipper DUF972 PF06156.8 EIE90673.1 - 2.9e-05 24.3 6.9 2.9e-05 24.3 4.8 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF972) bZIP_Maf PF03131.12 EIE90673.1 - 4.9e-05 23.5 9.0 4.9e-05 23.5 6.2 2.4 1 1 2 3 3 3 1 bZIP Maf transcription factor DUF2205 PF10224.4 EIE90673.1 - 0.0004 19.8 5.0 0.0012 18.3 3.5 1.9 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) DUF904 PF06005.7 EIE90673.1 - 0.0019 18.4 8.4 0.0019 18.4 5.8 2.0 2 0 0 2 2 1 1 Protein of unknown function (DUF904) SlyX PF04102.7 EIE90673.1 - 0.0024 18.2 6.8 0.0024 18.2 4.7 2.4 3 0 0 3 3 1 1 SlyX V_ATPase_I PF01496.14 EIE90673.1 - 0.0027 15.6 6.4 0.003 15.5 4.4 1.2 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family GAS PF13851.1 EIE90673.1 - 0.0031 16.7 12.4 0.0032 16.6 7.6 1.6 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding Vac_Fusion PF02346.11 EIE90673.1 - 0.036 13.4 3.2 0.081 12.3 2.2 1.5 1 0 0 1 1 1 0 Chordopoxvirus fusion protein PDZ_assoc PF10600.4 EIE90673.1 - 0.076 13.3 0.1 16 5.8 0.0 2.5 2 0 0 2 2 2 0 PDZ-associated domain of NMDA receptors DUF2960 PF11173.3 EIE90673.1 - 0.078 13.2 0.1 0.28 11.5 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2960) ADIP PF11559.3 EIE90673.1 - 0.17 11.8 14.6 0.22 11.4 9.0 1.9 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF948 PF06103.6 EIE90673.1 - 0.2 11.5 2.4 1.3 8.8 1.3 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) YojJ PF10372.4 EIE90673.1 - 0.26 11.2 2.4 0.3 10.9 0.3 2.1 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus DUF4140 PF13600.1 EIE90673.1 - 0.33 11.4 10.0 0.058 13.8 3.2 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) TSC22 PF01166.13 EIE90673.1 - 0.37 10.7 10.3 0.17 11.8 4.5 2.5 2 0 0 2 2 2 0 TSC-22/dip/bun family Phage_GPO PF05929.6 EIE90673.1 - 0.44 9.7 5.0 0.7 9.0 3.4 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase SseC PF04888.7 EIE90673.1 - 0.46 9.7 2.7 0.61 9.3 1.9 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Macoilin PF09726.4 EIE90673.1 - 0.52 8.5 16.9 0.038 12.2 8.1 1.7 2 0 0 2 2 2 0 Transmembrane protein APG6 PF04111.7 EIE90673.1 - 0.7 8.8 16.0 0.2 10.6 9.1 1.5 1 1 0 1 1 1 0 Autophagy protein Apg6 Atg14 PF10186.4 EIE90673.1 - 0.71 8.7 13.0 1.5 7.6 9.0 1.6 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Ax_dynein_light PF10211.4 EIE90673.1 - 0.76 9.5 17.2 0.29 10.9 10.1 1.7 1 1 0 1 1 1 0 Axonemal dynein light chain Spc24 PF08286.6 EIE90673.1 - 2.1 8.0 10.0 0.22 11.1 3.6 1.9 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 K-box PF01486.12 EIE90673.1 - 2.3 8.0 16.6 3.8 7.3 3.0 2.6 1 1 1 2 2 2 0 K-box region Phlebovirus_NSM PF07246.6 EIE90673.1 - 4.2 6.4 10.4 6.9 5.7 7.2 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DUF4337 PF14235.1 EIE90673.1 - 9.2 6.0 7.4 18 5.1 5.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) OPT PF03169.10 EIE90674.1 - 1.1e-180 602.2 45.8 1.3e-180 601.9 31.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3595 PF12166.3 EIE90676.1 - 0.035 12.9 0.5 0.038 12.8 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3595) Chromo PF00385.19 EIE90677.1 - 7.1e-12 44.8 0.5 1.4e-11 43.8 0.4 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DXP_reductoisom PF02670.11 EIE90678.1 - 0.16 12.4 0.1 0.24 11.9 0.1 1.2 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase zf-CCHC PF00098.18 EIE90680.1 - 1.8e-10 40.2 8.0 1.2e-05 24.9 0.3 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 EIE90680.1 - 0.0014 18.2 5.2 0.047 13.3 0.3 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.1 EIE90680.1 - 1.2 8.6 4.5 0.75 9.3 0.3 2.3 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC_6 PF15288.1 EIE90680.1 - 1.7 8.3 8.2 0.078 12.6 1.2 2.1 1 1 1 2 2 2 0 Zinc knuckle RasGEF PF00617.14 EIE90681.1 - 1.7e-62 210.4 0.2 6.4e-62 208.6 0.1 2.0 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EIE90681.1 - 3.3e-27 94.6 0.6 1.5e-26 92.5 0.4 2.2 1 0 0 1 1 1 1 RasGEF N-terminal motif WW PF00397.21 EIE90681.1 - 4.2e-08 32.8 0.3 9.2e-08 31.8 0.2 1.6 1 0 0 1 1 1 1 WW domain zf-Mss51 PF13824.1 EIE90682.1 - 5.3e-18 64.6 14.4 1.1e-17 63.5 10.0 1.6 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 Rad50_zn_hook PF04423.9 EIE90682.1 - 0.072 12.5 0.5 0.32 10.4 0.1 2.3 2 0 0 2 2 2 0 Rad50 zinc hook motif OrfB_Zn_ribbon PF07282.6 EIE90682.1 - 5.7 6.6 8.9 14 5.4 6.2 1.7 1 0 0 1 1 1 0 Putative transposase DNA-binding domain EMP70 PF02990.11 EIE90684.1 - 6.1e-162 539.7 18.1 7.4e-162 539.4 12.6 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 DUF4231 PF14015.1 EIE90684.1 - 2.3 8.2 8.9 30 4.6 0.3 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF4231) TPR_11 PF13414.1 EIE90685.1 - 2.3e-55 184.1 36.0 3e-12 45.9 0.1 12.8 12 1 1 13 13 13 9 TPR repeat TPR_2 PF07719.12 EIE90685.1 - 9e-46 150.1 38.5 7e-05 22.4 0.0 18.2 18 0 0 18 18 18 9 Tetratricopeptide repeat TPR_1 PF00515.23 EIE90685.1 - 3.5e-40 134.0 28.3 2e-06 27.1 0.0 14.1 15 0 0 15 15 14 9 Tetratricopeptide repeat TPR_12 PF13424.1 EIE90685.1 - 6.6e-33 112.4 42.3 5.3e-07 29.4 0.0 13.6 7 4 5 13 13 13 10 Tetratricopeptide repeat TPR_16 PF13432.1 EIE90685.1 - 9.6e-32 108.9 28.4 0.00064 20.3 0.2 12.0 9 2 3 14 14 13 6 Tetratricopeptide repeat TPR_8 PF13181.1 EIE90685.1 - 8.8e-27 90.8 21.4 0.00013 21.4 0.0 14.8 15 0 0 15 15 15 5 Tetratricopeptide repeat TPR_14 PF13428.1 EIE90685.1 - 3.2e-26 89.4 21.2 0.0032 17.9 0.1 15.7 10 4 6 16 16 15 5 Tetratricopeptide repeat TPR_17 PF13431.1 EIE90685.1 - 5.4e-26 88.5 32.3 0.0084 16.2 0.0 16.4 18 0 0 18 18 15 5 Tetratricopeptide repeat TPR_19 PF14559.1 EIE90685.1 - 5.7e-26 90.6 14.5 9.8e-05 22.6 0.0 11.7 10 2 2 12 12 12 6 Tetratricopeptide repeat TPR_7 PF13176.1 EIE90685.1 - 2e-12 45.8 23.0 0.0062 16.2 0.0 10.5 11 1 1 12 12 8 4 Tetratricopeptide repeat TPR_9 PF13371.1 EIE90685.1 - 4.4e-07 29.6 12.8 0.002 17.9 0.0 7.8 9 1 2 11 11 10 1 Tetratricopeptide repeat TPR_6 PF13174.1 EIE90685.1 - 8.3e-07 29.0 35.2 6.1 7.5 0.0 14.0 16 0 0 16 16 14 2 Tetratricopeptide repeat TPR_10 PF13374.1 EIE90685.1 - 4.2e-05 23.3 18.4 4.1 7.4 0.1 9.6 11 0 0 11 11 11 2 Tetratricopeptide repeat NARP1 PF12569.3 EIE90685.1 - 7.3e-05 21.7 2.4 3.5 6.2 0.0 4.9 4 1 1 5 5 5 2 NMDA receptor-regulated protein 1 PPR_3 PF13812.1 EIE90685.1 - 0.074 13.3 0.1 15 6.1 0.0 3.5 2 0 0 2 2 2 0 Pentatricopeptide repeat domain PerC PF06069.6 EIE90685.1 - 0.092 12.7 0.0 0.75 9.8 0.0 2.5 2 0 0 2 2 2 0 PerC transcriptional activator TPR_20 PF14561.1 EIE90685.1 - 0.3 11.2 6.5 4.4 7.4 0.0 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_4 PF07721.9 EIE90685.1 - 1.4 9.5 17.7 8.6 7.1 0.1 6.8 9 0 0 9 9 7 0 Tetratricopeptide repeat Thioredoxin PF00085.15 EIE90686.1 - 6.8e-15 54.6 0.0 7.2e-15 54.5 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 EIE90686.1 - 1e-06 28.6 0.0 1.1e-06 28.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EIE90686.1 - 0.00014 22.0 0.1 0.00041 20.5 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EIE90686.1 - 0.0005 20.1 0.1 0.0011 19.0 0.1 1.6 1 1 0 1 1 1 1 Thioredoxin-like DUF836 PF05768.9 EIE90686.1 - 0.049 13.8 0.0 0.058 13.6 0.0 1.2 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) TrbC_Ftype PF09673.5 EIE90686.1 - 0.056 13.0 0.0 0.059 12.9 0.0 1.1 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein Redoxin PF08534.5 EIE90686.1 - 0.12 11.8 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 Redoxin Glutaredoxin PF00462.19 EIE90686.1 - 0.14 12.1 0.0 0.29 11.1 0.0 1.6 1 1 0 1 1 1 0 Glutaredoxin RRM_1 PF00076.17 EIE90687.1 - 1.1e-19 69.7 0.2 1.5e-19 69.3 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE90687.1 - 6e-15 54.9 0.0 8.6e-15 54.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE90687.1 - 5.8e-10 38.8 0.0 9.8e-10 38.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EIE90687.1 - 0.14 11.9 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif z-alpha PF02295.12 EIE90688.1 - 0.024 14.4 0.1 0.07 12.9 0.0 1.7 1 1 1 2 2 2 0 Adenosine deaminase z-alpha domain DUF4436 PF14494.1 EIE90689.1 - 1.1e-21 77.2 0.5 1.8e-21 76.6 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4436) DUF4442 PF14539.1 EIE90689.1 - 4.6e-16 58.9 0.0 3.7e-15 56.0 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4442) TPR_2 PF07719.12 EIE90689.1 - 0.00086 19.0 0.0 0.0023 17.7 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 EIE90689.1 - 0.0018 17.8 0.0 0.0048 16.4 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat F-box-like PF12937.2 EIE90689.1 - 0.0053 16.4 0.2 0.012 15.3 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIE90689.1 - 0.046 13.3 0.0 0.14 11.8 0.0 1.8 1 0 0 1 1 1 0 F-box domain Peripla_BP_1 PF00532.16 EIE90689.1 - 0.066 12.4 0.1 0.11 11.6 0.1 1.2 1 0 0 1 1 1 0 Periplasmic binding proteins and sugar binding domain of LacI family TPR_11 PF13414.1 EIE90689.1 - 0.084 12.5 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 TPR repeat DUF562 PF04763.7 EIE90689.1 - 0.11 11.7 0.0 0.64 9.2 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF562) DDE_Tnp_4 PF13359.1 EIE90695.1 - 5.5e-06 26.0 0.4 1.1e-05 25.0 0.2 1.5 1 1 0 1 1 1 1 DDE superfamily endonuclease Integrin_alpha PF00357.15 EIE90695.1 - 0.17 11.7 0.2 0.17 11.7 0.1 2.3 2 0 0 2 2 2 0 Integrin alpha cytoplasmic region EF-hand_6 PF13405.1 EIE90697.1 - 0.049 13.5 0.0 0.067 13.1 0.0 1.2 1 0 0 1 1 1 0 EF-hand domain EF-hand_1 PF00036.27 EIE90697.1 - 0.11 11.8 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.1 EIE90697.1 - 0.12 12.5 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 EF-hand domain pair RRM_1 PF00076.17 EIE90700.1 - 8.5e-18 63.7 0.9 1e-05 25.0 0.1 4.6 4 1 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE90700.1 - 3.3e-15 55.8 0.0 5.3e-07 29.5 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE90700.1 - 5.2e-13 48.6 0.1 4.1e-06 26.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Remorin_N PF03766.8 EIE90700.1 - 0.017 14.8 0.0 0.044 13.5 0.0 1.7 1 0 0 1 1 1 0 Remorin, N-terminal region DUF1777 PF08648.7 EIE90700.1 - 0.22 11.2 40.8 0.42 10.3 28.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) MIP-T3 PF10243.4 EIE90700.1 - 0.6 8.5 9.2 0.77 8.1 6.4 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 RVT_1 PF00078.22 EIE90701.1 - 8.1e-06 25.3 0.0 8.2e-06 25.3 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Cactin_mid PF10312.4 EIE90702.1 - 0.051 12.8 0.4 8.6 5.5 0.0 2.4 2 1 0 2 2 2 0 Conserved mid region of cactin zf-CCHC PF00098.18 EIE90703.1 - 4.7e-08 32.5 12.9 0.00047 19.9 0.3 2.3 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 EIE90703.1 - 0.0022 17.6 7.2 0.21 11.2 0.3 2.6 2 0 0 2 2 2 2 Zinc knuckle RRM_1 PF00076.17 EIE90703.1 - 0.0048 16.5 0.0 0.32 10.6 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC_2 PF13696.1 EIE90703.1 - 1.7 8.1 9.1 1.5 8.4 0.2 2.4 2 0 0 2 2 2 0 Zinc knuckle HTH_28 PF13518.1 EIE90704.1 - 4.1e-08 33.0 0.1 1.8e-05 24.6 0.1 2.3 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_29 PF13551.1 EIE90704.1 - 3.3e-07 30.4 0.0 5.7e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EIE90704.1 - 7.3e-07 28.6 0.1 0.00071 19.1 0.0 2.4 2 0 0 2 2 2 2 Homeodomain-like domain HTH_32 PF13565.1 EIE90704.1 - 6.4e-06 26.8 0.0 1.7e-05 25.4 0.0 1.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_17 PF12728.2 EIE90704.1 - 0.00027 21.1 0.0 0.58 10.4 0.0 2.5 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_Tnp_1 PF01527.15 EIE90704.1 - 0.00049 19.9 0.1 0.0021 17.9 0.0 1.9 2 0 0 2 2 2 1 Transposase HTH_Tnp_Tc3_2 PF01498.13 EIE90704.1 - 0.052 13.6 0.0 0.12 12.4 0.0 1.7 1 1 0 1 1 1 0 Transposase RVT_1 PF00078.22 EIE90706.1 - 8.2e-34 116.8 0.0 1.3e-33 116.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EIE90706.1 - 4.2e-08 32.8 0.7 1.1e-07 31.5 0.5 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EIE90706.1 - 0.00012 22.1 0.1 0.00039 20.4 0.0 2.0 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family DUF446 PF04287.7 EIE90706.1 - 0.041 13.6 0.0 0.13 12.0 0.0 1.9 1 0 0 1 1 1 0 tRNA pseudouridine synthase C zf-CCHC PF00098.18 EIE90707.1 - 0.0031 17.3 11.9 0.0054 16.5 0.2 3.4 3 0 0 3 3 3 1 Zinc knuckle RRM_1 PF00076.17 EIE90707.1 - 0.0098 15.5 0.0 0.31 10.7 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lar_restr_allev PF14354.1 EIE90707.1 - 0.033 14.4 1.8 0.068 13.4 1.3 1.5 1 0 0 1 1 1 0 Restriction alleviation protein Lar RRM_6 PF14259.1 EIE90707.1 - 0.089 12.7 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-CCHC_6 PF15288.1 EIE90707.1 - 0.34 10.6 9.6 0.14 11.8 0.5 3.0 1 1 1 2 2 2 0 Zinc knuckle Glyco_hydro_28 PF00295.12 EIE90708.1 - 1.3e-66 224.7 25.7 1.8e-66 224.3 17.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Kelch_4 PF13418.1 EIE90711.1 - 1.2e-15 56.9 10.3 2.1e-05 24.2 0.0 6.4 5 1 1 6 6 6 3 Galactose oxidase, central domain Kelch_3 PF13415.1 EIE90711.1 - 3.7e-11 42.8 22.8 3.2e-05 23.9 0.2 6.8 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_6 PF13964.1 EIE90711.1 - 6.1e-10 38.8 21.8 0.022 14.8 0.4 7.1 5 2 1 6 6 6 3 Kelch motif Kelch_1 PF01344.20 EIE90711.1 - 3.4e-07 29.6 17.2 0.3 10.6 0.3 5.6 5 1 0 5 5 5 4 Kelch motif Kelch_5 PF13854.1 EIE90711.1 - 2.7e-06 27.1 6.7 2 8.4 0.0 5.8 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.10 EIE90711.1 - 4.8e-06 26.1 9.2 1.7 8.5 0.1 6.3 6 2 0 6 6 6 3 Kelch motif SKG6 PF08693.5 EIE90711.1 - 0.043 13.1 0.5 0.11 11.8 0.4 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain YopD PF05844.7 EIE90711.1 - 0.087 11.8 0.1 0.14 11.1 0.1 1.2 1 0 0 1 1 1 0 YopD protein DUF3042 PF11240.3 EIE90711.1 - 0.32 10.8 3.0 0.9 9.3 2.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) MAPEG PF01124.13 EIE90713.1 - 0.0002 20.9 9.4 0.0021 17.6 6.5 2.0 1 1 0 1 1 1 1 MAPEG family DUF1077 PF06417.7 EIE90714.1 - 7.2e-47 157.8 2.3 9e-47 157.5 1.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) RRM_6 PF14259.1 EIE90715.1 - 8.4e-15 54.5 0.1 2.9e-08 33.5 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EIE90715.1 - 1.9e-13 49.8 0.2 1.7e-06 27.5 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE90715.1 - 2.2e-12 46.6 0.2 7.9e-10 38.4 0.1 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EIE90715.1 - 2.4e-08 33.5 0.0 0.00052 19.7 0.0 2.5 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif PWI PF01480.12 EIE90715.1 - 0.00051 20.0 0.0 0.0014 18.6 0.0 1.8 1 0 0 1 1 1 1 PWI domain zf-CCCH PF00642.19 EIE90715.1 - 0.0017 18.0 0.8 0.0036 16.9 0.6 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_3 PF08777.6 EIE90715.1 - 0.015 15.1 10.8 0.49 10.2 0.0 3.7 3 1 0 3 3 3 0 RNA binding motif Dict-STAT-coil PF09267.5 EIE90715.1 - 0.22 11.7 10.4 0.43 10.8 7.2 1.4 1 0 0 1 1 1 0 Dictyostelium STAT, coiled coil DUF2762 PF10960.3 EIE90715.1 - 0.5 10.1 5.5 1.4 8.6 3.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2762) Prominin PF05478.6 EIE90715.1 - 3.4 5.0 7.7 4.8 4.5 5.4 1.1 1 0 0 1 1 1 0 Prominin Nefa_Nip30_N PF10187.4 EIE90716.1 - 4e-16 59.0 16.9 4e-16 59.0 11.7 2.4 2 1 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF572 PF04502.8 EIE90716.1 - 0.0014 17.9 24.3 0.0018 17.6 16.8 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) Prp19_bind PF06991.6 EIE90716.1 - 0.046 12.9 24.9 0.48 9.6 9.8 2.2 2 0 0 2 2 2 0 Splicing factor, Prp19-binding domain HXXSHH PF07586.6 EIE90716.1 - 0.56 9.0 5.1 1 8.2 3.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) Ribosomal_L18ae PF01775.12 EIE90718.1 - 1.9e-58 195.7 2.4 2.4e-58 195.4 1.6 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain SOBP PF15279.1 EIE90719.1 - 0.055 13.8 4.4 0.059 13.7 3.0 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein Methyltransf_11 PF08241.7 EIE90720.1 - 5.9e-15 55.5 0.0 1.1e-14 54.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIE90720.1 - 2.6e-13 50.0 0.0 4e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIE90720.1 - 2.4e-09 36.9 0.1 1.6e-08 34.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIE90720.1 - 9.6e-09 35.5 0.0 2.4e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EIE90720.1 - 2.7e-08 33.1 0.3 5.6e-06 25.5 0.0 2.6 2 1 0 2 2 2 2 Putative methyltransferase Methyltransf_12 PF08242.7 EIE90720.1 - 4.3e-08 33.5 0.1 2.2e-07 31.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIE90720.1 - 7e-07 28.6 0.0 1.3e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EIE90720.1 - 2.3e-06 28.1 0.0 8.6e-06 26.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EIE90720.1 - 4.8e-05 22.5 0.0 9.8e-05 21.5 0.0 1.5 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.13 EIE90720.1 - 0.0021 17.2 0.0 0.0032 16.7 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase MTS PF05175.9 EIE90720.1 - 0.0023 17.3 0.0 0.0042 16.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain DUF938 PF06080.7 EIE90720.1 - 0.0047 16.4 0.0 0.0073 15.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_26 PF13659.1 EIE90720.1 - 0.0063 16.5 0.0 0.024 14.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EIE90720.1 - 0.0094 15.6 0.0 0.017 14.7 0.0 1.4 1 1 0 1 1 1 1 Hypothetical methyltransferase Tim54 PF11711.3 EIE90720.1 - 0.011 14.3 2.2 0.039 12.5 0.0 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 FtsJ PF01728.14 EIE90720.1 - 0.081 12.9 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_9 PF08003.6 EIE90720.1 - 0.092 11.4 0.0 0.15 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Nol1_Nop2_Fmu PF01189.12 EIE90721.1 - 2.5e-105 351.9 0.0 3.8e-105 351.3 0.0 1.3 1 0 0 1 1 1 1 NOL1/NOP2/sun family Met_10 PF02475.11 EIE90721.1 - 0.00033 20.3 0.0 0.00064 19.3 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_31 PF13847.1 EIE90721.1 - 0.00044 19.8 0.0 0.0013 18.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EIE90721.1 - 0.046 13.7 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 FtsJ-like methyltransferase Peptidase_M41 PF01434.13 EIE90722.1 - 5.5e-76 254.7 0.1 8.3e-76 254.1 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EIE90722.1 - 2.5e-43 147.4 0.0 6.2e-43 146.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) COX5A PF02284.11 EIE90722.1 - 2.6e-41 139.9 2.0 1.3e-40 137.6 0.1 2.7 3 0 0 3 3 3 1 Cytochrome c oxidase subunit Va FtsH_ext PF06480.10 EIE90722.1 - 5.4e-08 32.9 0.1 1.2e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 FtsH Extracellular AAA_17 PF13207.1 EIE90722.1 - 0.00019 22.2 0.0 0.0014 19.4 0.0 2.5 1 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EIE90722.1 - 0.00042 20.0 0.1 0.0034 17.0 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EIE90722.1 - 0.0011 19.1 0.3 0.22 11.6 0.1 2.8 1 1 1 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EIE90722.1 - 0.0013 17.8 0.5 0.063 12.3 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin TIP49 PF06068.8 EIE90722.1 - 0.0037 16.0 0.1 0.0063 15.2 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_19 PF13245.1 EIE90722.1 - 0.0041 16.8 0.7 0.015 14.9 0.5 2.0 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 EIE90722.1 - 0.0042 16.1 0.0 0.0088 15.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EIE90722.1 - 0.015 15.2 2.6 0.16 11.9 0.1 3.4 3 1 1 4 4 4 0 AAA ATPase domain AAA_2 PF07724.9 EIE90722.1 - 0.018 14.9 0.0 0.07 13.0 0.0 2.0 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 EIE90722.1 - 0.021 14.2 0.0 0.057 12.8 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.1 EIE90722.1 - 0.058 13.2 0.2 0.28 11.0 0.0 2.3 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.1 EIE90722.1 - 0.058 13.6 0.9 0.41 10.9 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.1 EIE90722.1 - 0.07 12.5 0.9 0.21 10.9 0.4 1.9 1 1 0 1 1 1 0 AAA domain GPP34 PF05719.6 EIE90722.1 - 0.11 12.6 1.0 0.19 11.8 0.1 1.9 2 0 0 2 2 2 0 Golgi phosphoprotein 3 (GPP34) Sec7 PF01369.15 EIE90722.1 - 4.4 6.9 7.0 0.26 10.9 0.2 2.3 3 0 0 3 3 2 0 Sec7 domain Ribonuclease_3 PF00636.21 EIE90723.1 - 3.7e-49 165.9 0.1 2.1e-24 86.1 0.0 2.8 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EIE90723.1 - 5.6e-26 90.9 0.0 2.9e-13 49.8 0.0 3.5 2 2 0 2 2 2 2 Ribonuclease-III-like Dicer_dimer PF03368.9 EIE90723.1 - 2.9e-22 78.2 0.6 3.8e-21 74.6 0.1 2.8 3 0 0 3 3 3 1 Dicer dimerisation domain Helicase_C PF00271.26 EIE90723.1 - 8.9e-18 63.9 0.0 2.4e-17 62.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain dsrm PF00035.20 EIE90723.1 - 0.0025 18.3 0.3 0.82 10.2 0.0 2.6 2 0 0 2 2 2 1 Double-stranded RNA binding motif PAZ PF02170.17 EIE90723.1 - 0.0028 16.9 0.0 0.011 15.0 0.0 2.0 2 0 0 2 2 2 1 PAZ domain ResIII PF04851.10 EIE90724.1 - 5.9e-13 49.0 0.1 1.3e-12 47.8 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EIE90724.1 - 8.1e-11 41.6 0.0 1.2e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase SNF2_N PF00176.18 EIE90724.1 - 0.0031 16.3 0.2 0.009 14.8 0.1 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain AAA_22 PF13401.1 EIE90724.1 - 0.09 12.9 0.0 0.22 11.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain ATP-gua_PtransN PF02807.10 EIE90724.1 - 0.093 12.8 0.3 0.71 10.0 0.1 2.4 2 1 0 2 2 2 0 ATP:guanido phosphotransferase, N-terminal domain AAA_26 PF13500.1 EIE90724.1 - 0.14 11.7 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain Sec8_exocyst PF04048.9 EIE90725.1 - 2e-22 79.3 0.1 8e-22 77.3 0.1 2.1 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain E1-E2_ATPase PF00122.15 EIE90726.1 - 2.9e-58 196.6 2.3 2.9e-58 196.6 1.6 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EIE90726.1 - 3.7e-44 150.4 12.2 3.7e-44 150.4 8.4 2.4 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EIE90726.1 - 1.5e-28 100.6 0.0 3.9e-28 99.3 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EIE90726.1 - 9.3e-21 73.6 0.0 1.8e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EIE90726.1 - 2.4e-15 57.2 0.0 5.2e-15 56.1 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EIE90726.1 - 5.3e-09 35.4 0.0 1.8e-07 30.5 0.0 2.7 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EIE90726.1 - 1.3e-05 24.9 0.3 0.00057 19.5 0.2 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase SpoA PF01052.15 EIE90726.1 - 0.04 13.5 0.0 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 Surface presentation of antigens (SPOA) DUF1514 PF07438.6 EIE90726.1 - 0.88 9.5 0.0 0.88 9.5 0.0 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF1514) Autoind_bind PF03472.10 EIE90727.1 - 0.046 12.9 0.1 0.14 11.4 0.0 1.9 2 0 0 2 2 2 0 Autoinducer binding domain Glyco_hydro_16 PF00722.16 EIE90728.1 - 4.2e-09 35.9 0.1 4.7e-08 32.5 0.0 2.1 1 1 1 2 2 2 1 Glycosyl hydrolases family 16 SKN1 PF03935.10 EIE90728.1 - 0.019 13.1 0.4 0.028 12.6 0.3 1.3 1 0 0 1 1 1 0 Beta-glucan synthesis-associated protein (SKN1) EF-hand_6 PF13405.1 EIE90732.1 - 0.057 13.3 0.0 0.074 12.9 0.0 1.2 1 0 0 1 1 1 0 EF-hand domain EF-hand_1 PF00036.27 EIE90732.1 - 0.098 12.0 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 EF hand Phosphoesterase PF04185.9 EIE90734.1 - 1.4e-84 284.4 1.4 1.9e-84 284.0 1.0 1.1 1 0 0 1 1 1 1 Phosphoesterase family VIT1 PF01988.14 EIE90735.1 - 1.3e-70 237.1 0.1 1.6e-70 236.9 0.0 1.1 1 0 0 1 1 1 1 VIT family DASH_Dad2 PF08654.5 EIE90738.1 - 2.4e-07 30.6 0.5 4.1e-07 29.9 0.4 1.3 1 0 0 1 1 1 1 DASH complex subunit Dad2 SpoVAD PF07451.6 EIE90738.1 - 0.023 13.1 0.1 0.027 12.9 0.1 1.0 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) DUF334 PF03904.8 EIE90738.1 - 0.041 13.2 1.3 0.047 13.0 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF334) DUF4163 PF13739.1 EIE90738.1 - 0.16 12.7 1.2 0.22 12.3 0.8 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4163) tRNA-synt_2b PF00587.20 EIE90739.1 - 1.3e-18 67.1 0.1 2.7e-14 53.1 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EIE90739.1 - 2.3e-16 59.7 7.1 2.3e-16 59.7 4.9 1.9 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain Pox_F11 PF04943.7 EIE90739.1 - 0.013 14.3 1.1 0.021 13.7 0.8 1.2 1 0 0 1 1 1 0 Poxvirus F11 protein Laminin_II PF06009.7 EIE90740.1 - 0.05 13.3 2.0 0.12 12.0 1.4 1.6 1 0 0 1 1 1 0 Laminin Domain II RRM_1 PF00076.17 EIE90741.1 - 1.5e-38 130.2 0.0 7.9e-19 67.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE90741.1 - 1.8e-21 75.8 0.0 1.5e-09 37.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE90741.1 - 5.7e-17 61.3 0.0 1.9e-08 34.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 EIE90741.1 - 0.0046 16.4 0.1 0.088 12.3 0.0 2.3 2 0 0 2 2 2 1 Ribonuclease B OB domain Limkain-b1 PF11608.3 EIE90741.1 - 0.0071 16.0 0.0 5 6.9 0.0 2.3 2 0 0 2 2 2 2 Limkain b1 CMV_1a_C PF12503.3 EIE90741.1 - 0.13 11.9 0.0 8.6 6.1 0.0 2.3 2 0 0 2 2 2 0 Cucumber mosaic virus 1a protein C terminal HSF_DNA-bind PF00447.12 EIE90742.1 - 7.7e-31 106.3 0.8 1.8e-30 105.1 0.6 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.19 EIE90742.1 - 7.4e-25 87.1 0.1 1.8e-24 85.8 0.1 1.7 1 0 0 1 1 1 1 Response regulator receiver domain DUF3130 PF11328.3 EIE90742.1 - 0.037 14.0 0.6 0.12 12.3 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3130 V_ATPase_I PF01496.14 EIE90742.1 - 0.21 9.4 3.9 0.28 8.9 2.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 EIE90742.1 - 0.87 9.1 4.8 1.4 8.4 3.4 1.3 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 EIE90742.1 - 0.97 8.4 8.7 1.5 7.8 6.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Vps51 PF08700.6 EIE90742.1 - 1.1 9.0 10.6 15 5.4 5.7 3.1 2 1 0 2 2 2 0 Vps51/Vps67 DUF972 PF06156.8 EIE90742.1 - 2 8.8 5.0 4.7 7.6 3.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) AKNA PF12443.3 EIE90742.1 - 2.4 8.1 7.9 0.36 10.8 1.3 2.7 2 1 1 3 3 3 0 AT-hook-containing transcription factor bZIP_1 PF00170.16 EIE90744.1 - 1.4e-08 34.5 21.3 1.5e-08 34.4 14.0 1.7 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EIE90744.1 - 1.2e-05 24.9 17.7 1.2e-05 24.9 12.3 3.2 2 1 2 4 4 4 1 Basic region leucine zipper Macoilin PF09726.4 EIE90744.1 - 0.00044 18.6 7.2 0.00049 18.5 5.0 1.1 1 0 0 1 1 1 1 Transmembrane protein bZIP_Maf PF03131.12 EIE90744.1 - 0.00048 20.3 11.4 0.00048 20.3 7.9 2.4 1 1 1 2 2 2 1 bZIP Maf transcription factor DUF4407 PF14362.1 EIE90744.1 - 0.0018 17.2 2.9 0.0024 16.8 2.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) FTZ PF03867.9 EIE90744.1 - 0.0029 16.8 4.3 0.0054 16.0 2.8 1.7 1 1 0 1 1 1 1 Fushi tarazu (FTZ), N-terminal region DUF106 PF01956.11 EIE90744.1 - 0.003 17.1 5.3 0.0041 16.6 2.3 1.9 2 0 0 2 2 2 1 Integral membrane protein DUF106 Mnd1 PF03962.10 EIE90744.1 - 0.0068 16.0 8.4 0.011 15.4 5.8 1.4 1 0 0 1 1 1 1 Mnd1 family FHIPEP PF00771.15 EIE90744.1 - 0.0095 14.3 4.7 0.012 13.9 3.3 1.1 1 0 0 1 1 1 1 FHIPEP family DUF4064 PF13273.1 EIE90744.1 - 0.016 15.2 0.4 0.061 13.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) DUF342 PF03961.8 EIE90744.1 - 0.025 13.0 10.6 0.029 12.7 7.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Zwint PF15556.1 EIE90744.1 - 0.036 13.3 12.2 0.046 12.9 8.4 1.1 1 0 0 1 1 1 0 ZW10 interactor DUF3987 PF13148.1 EIE90744.1 - 0.053 12.0 5.2 0.072 11.6 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) OppC_N PF12911.2 EIE90744.1 - 0.078 12.3 0.2 0.38 10.1 0.0 2.1 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C HCO3_cotransp PF00955.16 EIE90744.1 - 0.091 11.3 1.3 0.12 11.0 0.9 1.1 1 0 0 1 1 1 0 HCO3- transporter family Exonuc_VII_L PF02601.10 EIE90744.1 - 0.46 9.6 11.3 0.59 9.2 7.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3835 PF12927.2 EIE90744.1 - 0.6 11.1 9.1 3 8.8 6.3 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF3835) DUF607 PF04678.8 EIE90744.1 - 1 9.2 6.4 4.5 7.1 4.5 1.9 1 1 0 1 1 1 0 Protein of unknown function, DUF607 V_ATPase_I PF01496.14 EIE90744.1 - 1.6 6.4 8.1 2.1 6.0 5.6 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6 PF04111.7 EIE90744.1 - 1.8 7.5 16.2 2.6 7.0 11.2 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DnaG_DnaB_bind PF08278.6 EIE90744.1 - 4.2 7.5 11.8 2.5 8.3 6.7 1.7 1 1 1 2 2 2 0 DNA primase DnaG DnaB-binding Atg14 PF10186.4 EIE90744.1 - 6.8 5.5 18.0 9.5 5.0 12.5 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4044 PF13253.1 EIE90744.1 - 7.7 5.7 5.7 1.5 8.0 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4044) DUF912 PF06024.7 EIE90744.1 - 9.1 6.3 9.2 0.73 9.9 0.8 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DIL PF01843.14 EIE90745.1 - 8.2e-23 80.2 4.7 1.9e-22 79.0 3.2 1.7 1 0 0 1 1 1 1 DIL domain Ank PF00023.25 EIE90745.1 - 1e-18 66.0 0.0 1.4e-08 34.1 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 EIE90745.1 - 3.1e-18 65.8 0.0 1.6e-17 63.5 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EIE90745.1 - 3.7e-16 58.7 0.0 2.5e-09 37.0 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIE90745.1 - 2.8e-13 48.7 1.3 8.1e-07 28.6 0.0 4.2 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.1 EIE90745.1 - 1.9e-10 40.9 0.0 1.3e-09 38.3 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) ANF_receptor PF01094.23 EIE90746.1 - 8.8e-29 100.3 0.0 1.2e-28 99.8 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.1 EIE90746.1 - 6e-12 45.5 0.1 7.6e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein Asp_Glu_race PF01177.17 EIE90746.1 - 0.0057 16.5 0.0 0.013 15.4 0.0 1.5 1 1 0 1 1 1 1 Asp/Glu/Hydantoin racemase 7tm_3 PF00003.17 EIE90747.1 - 2e-10 40.4 9.0 2.5e-10 40.1 6.2 1.1 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR WD40 PF00400.27 EIE90748.1 - 3.5e-18 64.7 1.1 4.5e-09 35.8 0.0 2.1 2 0 0 2 2 2 2 WD domain, G-beta repeat eIF2A PF08662.6 EIE90748.1 - 0.0053 16.4 0.3 0.7 9.5 0.1 2.1 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 EIE90748.1 - 0.011 14.4 0.0 0.015 14.0 0.0 1.2 1 1 0 1 1 1 0 Nup133 N terminal like Perilipin PF03036.11 EIE90750.1 - 8.2e-12 44.6 1.3 1.2e-07 30.9 0.0 2.1 1 1 1 2 2 2 2 Perilipin family Fib_alpha PF08702.5 EIE90750.1 - 0.18 11.8 2.8 0.41 10.7 1.9 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Chorismate_synt PF01264.16 EIE90751.1 - 6.7e-132 439.1 0.0 7.7e-132 438.9 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase zf-ZPR1 PF03367.8 EIE90753.1 - 1.3e-112 372.2 0.1 1.9e-56 189.6 0.0 2.1 2 0 0 2 2 2 2 ZPR1 zinc-finger domain DnaJ_CXXCXGXG PF00684.14 EIE90753.1 - 0.026 14.5 3.5 1 9.4 0.6 2.5 2 0 0 2 2 2 0 DnaJ central domain UPF0547 PF10571.4 EIE90753.1 - 0.12 12.0 12.1 0.37 10.5 0.1 3.3 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 zinc-ribbons_6 PF07191.7 EIE90753.1 - 0.34 10.7 7.1 0.37 10.5 0.6 2.7 2 1 0 2 2 2 0 zinc-ribbons zf-ribbon_3 PF13248.1 EIE90753.1 - 0.36 10.1 10.8 2.7 7.3 0.1 3.2 2 1 0 2 2 2 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 EIE90753.1 - 0.38 10.7 6.9 26 4.8 0.0 4.2 4 0 0 4 4 4 0 Zinc ribbon domain Lar_restr_allev PF14354.1 EIE90753.1 - 2.5 8.4 10.4 0.34 11.2 0.8 2.9 2 1 0 2 2 2 0 Restriction alleviation protein Lar Zn_Tnp_IS1595 PF12760.2 EIE90753.1 - 5.5 6.8 6.6 11 5.9 0.0 3.5 4 0 0 4 4 4 0 Transposase zinc-ribbon domain zf-H2C2_2 PF13465.1 EIE90753.1 - 5.9 7.3 7.6 14 6.1 0.1 3.5 3 0 0 3 3 3 0 Zinc-finger double domain Elf1 PF05129.8 EIE90753.1 - 7.5 6.3 8.0 11 5.8 0.4 2.9 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like zf-H2C2_2 PF13465.1 EIE90754.1 - 1.3e-11 44.1 18.1 1.6e-06 28.1 2.5 3.4 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 EIE90754.1 - 1.8e-09 37.3 10.6 1.2e-05 25.3 2.0 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIE90754.1 - 1.3e-07 31.4 10.2 0.0014 18.8 2.0 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger Pkinase PF00069.20 EIE90755.1 - 5e-60 202.8 0.1 4.6e-57 193.1 0.0 2.6 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIE90755.1 - 1.3e-35 122.6 0.0 4.2e-31 107.9 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EIE90755.1 - 1.3e-06 27.5 0.0 2.5e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EIE90755.1 - 0.0066 16.2 0.1 0.014 15.1 0.1 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family H_PPase PF03030.11 EIE90756.1 - 0.026 12.8 1.1 0.028 12.6 0.7 1.0 1 0 0 1 1 1 0 Inorganic H+ pyrophosphatase Apq12 PF12716.2 EIE90756.1 - 1.6 8.4 17.6 0.24 11.1 9.6 1.6 2 0 0 2 2 2 0 Nuclear pore assembly and biogenesis CPSF_A PF03178.10 EIE90757.1 - 4.7e-58 196.7 0.0 1.9e-57 194.7 0.0 2.0 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.4 EIE90757.1 - 9.4e-57 192.2 0.9 2e-56 191.1 0.6 1.5 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Recep_L_domain PF01030.19 EIE90759.1 - 9.3e-10 38.4 2.7 0.029 14.3 0.1 4.8 1 1 3 4 4 4 3 Receptor L domain MFS_1 PF07690.11 EIE90760.1 - 1.6e-32 112.6 23.4 2e-32 112.2 16.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIE90760.1 - 2e-10 39.8 16.7 1.3e-09 37.1 11.5 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 EIE90760.1 - 1.4e-06 27.0 13.2 1.3e-05 23.7 1.4 2.3 1 1 1 2 2 2 2 MFS/sugar transport protein TRI12 PF06609.8 EIE90760.1 - 0.00051 18.3 0.3 0.00094 17.4 0.2 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Prp19 PF08606.6 EIE90762.1 - 1.3e-33 114.4 2.5 1.3e-33 114.4 1.7 1.7 2 0 0 2 2 2 1 Prp19/Pso4-like WD40 PF00400.27 EIE90762.1 - 7.8e-30 101.6 1.2 2.3e-06 27.2 0.0 5.4 5 0 0 5 5 5 5 WD domain, G-beta repeat U-box PF04564.10 EIE90762.1 - 0.0054 16.6 0.0 0.014 15.3 0.0 1.7 1 0 0 1 1 1 1 U-box domain DUF1631 PF07793.6 EIE90762.1 - 0.0093 14.1 3.5 0.014 13.5 2.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1631) Nbas_N PF15492.1 EIE90762.1 - 0.018 14.1 0.1 0.5 9.4 0.0 2.2 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal DUF3450 PF11932.3 EIE90762.1 - 0.044 13.0 4.7 0.096 11.9 3.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF3312 PF11768.3 EIE90762.1 - 0.059 11.5 0.0 0.59 8.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) DUF1395 PF07160.7 EIE90762.1 - 0.18 11.2 3.5 0.28 10.6 2.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1395) DUF1269 PF06897.7 EIE90762.1 - 0.19 11.7 0.6 47 4.0 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1269) HIG_1_N PF04588.8 EIE90763.1 - 2.7e-06 26.9 1.9 3.3e-06 26.7 0.5 1.7 2 0 0 2 2 2 1 Hypoxia induced protein conserved region RskA PF10099.4 EIE90763.1 - 0.037 13.7 0.1 0.25 11.0 0.1 1.9 1 1 0 1 1 1 0 Anti-sigma-K factor rskA Mito_carr PF00153.22 EIE90767.1 - 2.6e-60 200.1 2.9 3.1e-22 78.0 0.0 3.3 2 2 1 3 3 3 3 Mitochondrial carrier protein PBP PF01161.15 EIE90769.1 - 9.4e-26 90.4 0.1 1.2e-25 90.0 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein DUF2618 PF10940.3 EIE90769.1 - 0.076 12.7 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2618) NAD_Gly3P_dh_C PF07479.9 EIE90770.1 - 1.4e-53 180.6 0.3 1.9e-53 180.2 0.2 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.18 EIE90770.1 - 3.6e-15 56.0 0.1 1.1e-14 54.3 0.0 1.8 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DXPR_C PF13288.1 EIE90770.1 - 0.13 12.2 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 DXP reductoisomerase C-terminal domain GATase_4 PF13230.1 EIE90771.1 - 6.7e-16 57.7 0.1 2.6e-15 55.8 0.1 1.8 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_2 PF00310.16 EIE90771.1 - 5.3e-07 28.6 0.1 1.4e-06 27.2 0.0 1.7 1 1 1 2 2 2 1 Glutamine amidotransferases class-II GATase_6 PF13522.1 EIE90771.1 - 3.3e-06 27.0 0.0 6.1e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain HSF_DNA-bind PF00447.12 EIE90772.1 - 1.8e-32 111.6 1.6 1.8e-32 111.6 1.1 1.8 2 0 0 2 2 2 1 HSF-type DNA-binding DUF4298 PF14131.1 EIE90772.1 - 0.015 15.1 1.5 0.036 13.9 1.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4298) HD_assoc PF13286.1 EIE90772.1 - 0.034 14.4 0.6 0.074 13.3 0.4 1.5 1 0 0 1 1 1 0 Phosphohydrolase-associated domain ALMS_motif PF15309.1 EIE90772.1 - 0.075 12.8 2.1 0.12 12.1 1.5 1.3 1 0 0 1 1 1 0 ALMS motif Phage_GPO PF05929.6 EIE90772.1 - 0.08 12.1 0.9 0.12 11.6 0.6 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase TPD52 PF04201.10 EIE90772.1 - 0.14 11.8 1.5 0.26 11.0 1.0 1.3 1 0 0 1 1 1 0 Tumour protein D52 family SseC PF04888.7 EIE90772.1 - 5.1 6.3 12.1 17 4.6 8.4 1.7 1 1 0 1 1 1 0 Secretion system effector C (SseC) like family Peptidase_M13_N PF05649.8 EIE90773.1 - 5.1e-52 177.2 2.2 1.2e-51 175.9 1.6 1.5 1 1 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.16 EIE90773.1 - 7.4e-40 136.3 0.2 2.5e-39 134.5 0.0 2.1 3 0 0 3 3 3 1 Peptidase family M13 Peptidase_M48 PF01435.13 EIE90773.1 - 0.067 12.7 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M48 Chitin_synth_2 PF03142.10 EIE90774.1 - 2.1e-242 805.2 0.8 4.7e-242 804.0 0.6 1.6 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 EIE90774.1 - 2.1e-158 528.4 2.5 2.8e-158 528.0 1.7 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Glyco_trans_2_3 PF13632.1 EIE90774.1 - 8.3e-18 64.7 0.3 8.3e-18 64.7 0.2 2.3 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Cyt-b5 PF00173.23 EIE90774.1 - 2.2e-17 62.6 0.0 1.2e-13 50.5 0.0 2.7 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.1 EIE90774.1 - 1.1e-16 61.2 0.0 1.4e-14 54.4 0.0 2.4 1 1 1 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EIE90774.1 - 5.7e-05 22.8 0.0 0.0024 17.5 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EIE90774.1 - 7.3e-05 22.1 0.0 0.00044 19.5 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 21 AAA_5 PF07728.9 EIE90774.1 - 0.075 12.7 0.1 0.78 9.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) WBS_methylT PF12589.3 EIE90775.1 - 6.4e-17 61.8 10.4 1.1e-16 61.1 7.2 1.4 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 EIE90775.1 - 1.7e-11 44.4 0.0 3.6e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIE90775.1 - 2.9e-06 27.0 0.0 4.3e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIE90775.1 - 6.6e-06 25.7 0.0 1e-05 25.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIE90775.1 - 2e-05 24.8 0.0 4.3e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIE90775.1 - 2.6e-05 24.6 0.4 8.6e-05 22.9 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIE90775.1 - 5.8e-05 23.6 0.0 0.00012 22.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EIE90775.1 - 0.0056 15.8 0.4 0.011 14.8 0.0 1.7 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase AdoMet_MTase PF07757.8 EIE90775.1 - 0.0056 16.7 0.0 0.014 15.4 0.0 1.7 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase PCMT PF01135.14 EIE90775.1 - 0.0066 15.9 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 EIE90775.1 - 0.011 15.7 0.0 0.019 15.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 EIE90775.1 - 0.098 12.3 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Ribosomal_S13 PF00416.17 EIE90776.1 - 1.1e-25 90.1 0.1 1.4e-25 89.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 EIE90776.1 - 0.0017 17.0 0.0 0.0018 16.8 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) Pkinase PF00069.20 EIE90777.1 - 3.9e-33 114.6 0.0 5.5e-33 114.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE90777.1 - 1e-10 41.1 0.0 1.5e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase YrbL-PhoP_reg PF10707.4 EIE90777.1 - 0.024 13.9 0.0 0.053 12.8 0.0 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Cu-oxidase_3 PF07732.10 EIE90778.1 - 3.4e-34 117.0 2.9 4.9e-34 116.5 0.1 2.7 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.17 EIE90778.1 - 6.2e-26 91.1 0.0 2e-25 89.5 0.0 1.9 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EIE90778.1 - 7.6e-25 87.0 4.4 7.6e-25 87.0 3.0 3.9 3 1 0 3 3 3 2 Multicopper oxidase Proteasom_Rpn13 PF04683.8 EIE90779.1 - 2.2e-32 110.9 0.1 3.1e-32 110.4 0.0 1.2 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor S100PBPR PF15427.1 EIE90779.1 - 0.016 14.2 0.0 0.021 13.9 0.0 1.1 1 0 0 1 1 1 0 S100P-binding protein TDH PF03347.8 EIE90779.1 - 0.043 13.3 0.0 0.068 12.7 0.0 1.5 1 0 0 1 1 1 0 Vibrio thermostable direct hemolysin SUKH_6 PF14568.1 EIE90779.1 - 0.045 14.2 0.3 0.069 13.6 0.2 1.3 1 0 0 1 1 1 0 SMI1-KNR4 cell-wall SpoIISA_toxin PF14171.1 EIE90779.1 - 0.1 11.8 0.2 0.14 11.3 0.1 1.2 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system DUF3151 PF11349.3 EIE90780.1 - 0.024 14.6 0.0 0.033 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3151) PRP1_N PF06424.7 EIE90781.1 - 1.5 9.1 11.0 66 3.8 7.6 2.3 1 1 0 1 1 1 0 PRP1 splicing factor, N-terminal OSTbeta PF15048.1 EIE90781.1 - 2.3 8.2 5.1 0.79 9.8 0.6 2.1 1 1 1 2 2 2 0 Organic solute transporter subunit beta protein DDE_3 PF13358.1 EIE90783.1 - 4.2e-05 23.3 0.1 0.00018 21.3 0.0 1.9 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_29 PF13551.1 EIE90783.1 - 0.0084 16.2 0.1 0.028 14.5 0.0 1.9 1 1 0 1 1 1 1 Winged helix-turn helix ERG4_ERG24 PF01222.12 EIE90784.1 - 3.1e-96 322.5 9.6 3.5e-96 322.3 6.6 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family PEMT PF04191.8 EIE90784.1 - 0.00038 20.5 6.0 0.0067 16.5 0.0 2.7 3 0 0 3 3 3 2 Phospholipid methyltransferase Steroid_dh PF02544.11 EIE90784.1 - 0.0019 17.9 0.9 0.0019 17.9 0.6 2.4 1 1 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase HTH_Tnp_Tc3_2 PF01498.13 EIE90785.1 - 6.5e-05 22.9 1.1 0.00011 22.1 0.8 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.1 EIE90785.1 - 0.00034 20.3 0.0 0.00058 19.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease 2-oxoacid_dh PF00198.18 EIE90787.1 - 2.4e-75 252.7 0.1 3.9e-75 252.0 0.0 1.4 2 0 0 2 2 2 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EIE90787.1 - 2.2e-17 62.4 0.0 4.8e-17 61.3 0.0 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 EIE90787.1 - 1.3e-15 56.7 1.4 1.4e-15 56.6 0.2 1.7 2 0 0 2 2 2 1 e3 binding domain GCV_H PF01597.14 EIE90787.1 - 0.027 14.1 0.0 0.065 12.9 0.0 1.6 1 0 0 1 1 1 0 Glycine cleavage H-protein Biotin_lipoyl_2 PF13533.1 EIE90787.1 - 0.041 13.5 0.1 1.9 8.2 0.0 2.8 1 1 1 2 2 2 0 Biotin-lipoyl like DEAD PF00270.24 EIE90789.1 - 3.1e-42 143.9 0.0 1.3e-41 141.8 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIE90789.1 - 4.3e-19 68.1 0.1 2.6e-18 65.6 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EIE90789.1 - 5.9e-05 22.0 0.0 0.00014 20.7 0.0 1.7 1 1 1 2 2 2 1 SNF2 family N-terminal domain ResIII PF04851.10 EIE90789.1 - 7.6e-05 22.6 0.3 0.00017 21.4 0.2 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 EIE90789.1 - 0.00024 20.5 0.2 0.00028 20.2 0.1 1.3 1 0 0 1 1 1 1 SecA DEAD-like domain AAA_30 PF13604.1 EIE90789.1 - 0.00046 19.8 0.0 0.0058 16.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EIE90789.1 - 0.0038 16.9 0.0 0.015 15.0 0.0 2.0 1 0 0 1 1 1 1 Part of AAA domain PhoH PF02562.11 EIE90789.1 - 0.006 15.8 0.1 0.017 14.3 0.0 1.8 1 0 0 1 1 1 1 PhoH-like protein Helicase_C_2 PF13307.1 EIE90789.1 - 0.011 15.6 0.0 0.052 13.5 0.0 2.1 3 0 0 3 3 3 0 Helicase C-terminal domain AAA_22 PF13401.1 EIE90789.1 - 0.028 14.5 0.3 0.2 11.8 0.3 2.5 2 1 0 2 2 2 0 AAA domain RRM_1 PF00076.17 EIE90791.1 - 3.5e-30 103.4 0.0 4.3e-18 64.7 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE90791.1 - 5.2e-21 74.4 0.1 2e-12 46.9 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 EIE90791.1 - 4.7e-10 39.0 1.7 4.7e-08 32.5 0.2 2.4 2 0 0 2 2 2 2 Poly-adenylate binding protein, unique domain RRM_5 PF13893.1 EIE90791.1 - 1.2e-08 34.6 0.1 0.0012 18.6 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MgtE PF01769.11 EIE90793.1 - 9.2e-13 48.6 3.4 9.2e-13 48.6 2.4 1.5 2 0 0 2 2 2 1 Divalent cation transporter Tox-MPTase3 PF15639.1 EIE90793.1 - 0.0048 16.6 0.0 0.0077 15.9 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase toxin 3 DUF1282 PF06930.7 EIE90793.1 - 0.26 10.9 5.2 0.5 10.0 0.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1282) GNVR PF13807.1 EIE90793.1 - 0.41 10.4 3.4 0.7 9.6 0.0 2.7 3 0 0 3 3 3 0 G-rich domain on putative tyrosine kinase DUF4118 PF13493.1 EIE90793.1 - 0.94 9.7 14.4 0.96 9.6 3.9 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4118) Peptidase_S8 PF00082.17 EIE90794.1 - 9.8e-49 165.9 0.1 2.5e-48 164.6 0.1 1.7 1 1 0 1 1 1 1 Subtilase family PA PF02225.17 EIE90794.1 - 1.4e-16 60.0 1.9 4.2e-16 58.4 1.3 1.9 1 0 0 1 1 1 1 PA domain DUF1034 PF06280.7 EIE90794.1 - 3e-15 56.5 2.4 7.4e-15 55.3 1.7 1.7 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) Fn3-like PF14310.1 EIE90794.1 - 0.017 15.0 0.0 0.084 12.8 0.0 2.2 1 0 0 1 1 1 0 Fibronectin type III-like domain Inhibitor_I9 PF05922.11 EIE90794.1 - 0.02 15.4 0.5 0.1 13.1 0.4 2.2 1 1 0 1 1 1 0 Peptidase inhibitor I9 Peptidase_M13_N PF05649.8 EIE90795.1 - 4e-80 269.7 0.0 5.1e-80 269.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.16 EIE90795.1 - 2e-64 216.5 0.0 3.7e-64 215.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M48 PF01435.13 EIE90795.1 - 0.0026 17.3 0.0 0.007 15.9 0.0 1.7 1 0 0 1 1 1 1 Peptidase family M48 RasGAP PF00616.14 EIE90796.1 - 4.3e-39 134.2 0.1 2.1e-38 131.9 0.0 2.4 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.1 EIE90796.1 - 8.4e-18 64.7 1.2 2.2e-17 63.3 0.2 2.3 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain HEAT_2 PF13646.1 EIE90796.1 - 4e-05 23.7 0.1 0.048 13.9 0.0 4.1 3 0 0 3 3 3 1 HEAT repeats CRAL_TRIO PF00650.15 EIE90796.1 - 0.00025 20.5 0.1 0.00088 18.7 0.1 1.9 1 0 0 1 1 1 1 CRAL/TRIO domain HEAT PF02985.17 EIE90796.1 - 0.00034 20.4 4.9 0.021 14.9 0.0 4.2 3 0 0 3 3 3 1 HEAT repeat Glyco_hydro_28 PF00295.12 EIE90797.1 - 8.3e-72 241.8 28.5 1.1e-71 241.4 19.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Glyco_hydro_28 PF00295.12 EIE90799.1 - 3.2e-73 246.5 28.5 4e-73 246.1 19.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Glyco_hydro_28 PF00295.12 EIE90800.1 - 3.2e-73 246.5 28.5 4e-73 246.1 19.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 DUF303 PF03629.13 EIE90801.1 - 8.7e-40 136.5 0.0 1.4e-39 135.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF303) G-alpha PF00503.15 EIE90802.1 - 6.9e-29 100.7 1.6 8e-29 100.5 1.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EIE90802.1 - 0.0029 16.8 0.8 0.0075 15.5 0.1 1.9 1 1 1 2 2 2 1 ADP-ribosylation factor family MCM PF00493.18 EIE90802.1 - 0.0041 15.9 0.0 0.0063 15.3 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family AAA_29 PF13555.1 EIE90802.1 - 0.0066 15.9 0.0 0.016 14.7 0.0 1.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_15 PF13175.1 EIE90802.1 - 0.021 13.8 2.3 0.04 12.9 1.6 1.4 1 1 0 1 1 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.13 EIE90802.1 - 0.025 14.0 0.0 0.044 13.2 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_28 PF13521.1 EIE90802.1 - 0.036 14.0 0.0 0.053 13.4 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EIE90802.1 - 0.053 12.9 0.0 0.12 11.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain ComA PF02679.10 EIE90802.1 - 0.073 12.0 1.9 0.7 8.8 1.4 2.0 1 1 0 1 1 1 0 (2R)-phospho-3-sulfolactate synthase (ComA) Miro PF08477.8 EIE90802.1 - 0.099 13.1 0.3 0.29 11.6 0.2 1.9 1 1 0 1 1 1 0 Miro-like protein AAA_14 PF13173.1 EIE90802.1 - 0.11 12.3 0.3 0.29 11.0 0.2 1.8 1 1 0 1 1 1 0 AAA domain DDE_3 PF13358.1 EIE90803.1 - 0.0066 16.2 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease PAP1 PF08601.5 EIE90805.1 - 1e-05 25.3 0.1 1e-05 25.3 0.1 2.2 1 1 0 2 2 2 1 Transcription factor PAP1 DndB PF14072.1 EIE90806.1 - 0.022 13.9 0.1 0.026 13.6 0.1 1.2 1 0 0 1 1 1 0 DNA-sulfur modification-associated SSXRD PF09514.5 EIE90806.1 - 0.22 10.8 1.5 0.58 9.5 1.0 1.7 1 0 0 1 1 1 0 SSXRD motif TPR_12 PF13424.1 EIE90807.1 - 3.7e-06 26.7 0.6 0.014 15.3 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EIE90807.1 - 0.032 14.5 7.0 0.41 11.0 0.0 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat TOM20_plant PF06552.7 EIE90807.1 - 0.036 13.6 2.7 2.3 7.7 0.1 3.4 2 2 1 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 TPR_5 PF12688.2 EIE90807.1 - 0.043 13.8 0.7 2.5 8.1 0.0 2.7 3 0 0 3 3 3 0 Tetratrico peptide repeat TPR_11 PF13414.1 EIE90807.1 - 0.047 13.3 4.4 3.7 7.2 0.0 3.9 3 2 1 4 4 4 0 TPR repeat TPR_6 PF13174.1 EIE90807.1 - 0.099 13.1 0.8 23 5.7 0.0 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 EIE90807.1 - 0.1 12.5 3.3 77 3.4 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 EIE90807.1 - 0.26 10.9 4.5 0.64 9.7 0.4 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 EIE90807.1 - 2.3 8.3 10.8 1.2 9.2 0.7 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 EIE90807.1 - 6.6 6.7 6.2 15 5.6 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Las1 PF04031.8 EIE90808.1 - 2.1e-33 115.1 0.4 8e-33 113.2 0.1 1.9 2 1 0 2 2 2 1 Las1-like DUF1241 PF06840.6 EIE90808.1 - 0.07 12.3 0.1 1.9 7.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1241) DUF3425 PF11905.3 EIE90809.1 - 8.6e-11 41.8 5.6 5.3e-09 36.0 3.8 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) TPR_11 PF13414.1 EIE90810.1 - 8.7e-11 41.3 0.0 2.6e-06 26.9 0.0 3.2 1 1 2 3 3 3 3 TPR repeat zf-MYND PF01753.13 EIE90810.1 - 8.9e-08 31.8 11.7 1.8e-07 30.9 8.1 1.5 1 0 0 1 1 1 1 MYND finger TPR_1 PF00515.23 EIE90810.1 - 8.1e-06 25.2 0.5 0.00038 19.9 0.0 3.4 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EIE90810.1 - 2.3e-05 23.8 1.7 0.25 11.2 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EIE90810.1 - 0.00012 21.9 0.1 0.057 13.3 0.1 2.7 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 EIE90810.1 - 0.00013 21.8 0.1 0.011 15.8 0.0 3.4 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EIE90810.1 - 0.00055 19.6 1.4 0.11 12.4 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 EIE90810.1 - 0.0033 17.7 0.4 7.4 7.2 0.0 4.8 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 EIE90810.1 - 0.012 16.2 0.0 0.082 13.6 0.0 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EIE90810.1 - 0.029 14.9 0.0 0.5 11.1 0.0 3.0 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 EIE90810.1 - 0.068 13.5 3.0 8.8 6.7 0.0 3.4 2 2 1 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.20 EIE90814.1 - 4.7e-62 209.4 0.0 6e-62 209.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE90814.1 - 2.1e-40 138.4 0.0 3e-40 137.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 EIE90814.1 - 4.4e-18 65.4 3.9 1.1e-08 35.2 0.8 2.5 2 0 0 2 2 2 2 P21-Rho-binding domain Kinase-like PF14531.1 EIE90814.1 - 1.3e-07 30.9 0.0 2.6e-07 29.8 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 EIE90814.1 - 0.0088 15.1 0.1 0.015 14.3 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIE90814.1 - 0.091 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family ORC5_C PF14630.1 EIE90815.1 - 2.3e-46 158.4 0.9 2.8e-46 158.1 0.6 1.0 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus DUF4309 PF14172.1 EIE90815.1 - 0.057 13.4 0.1 0.89 9.5 0.0 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4309) ubiquitin PF00240.18 EIE90816.1 - 5e-35 118.7 1.3 6.5e-35 118.3 0.9 1.1 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.12 EIE90816.1 - 9.8e-31 105.1 11.1 1.6e-30 104.4 7.7 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.3 EIE90816.1 - 2.5e-20 71.9 1.0 4e-20 71.2 0.7 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EIE90816.1 - 2.9e-06 27.4 0.2 1e-05 25.6 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EIE90816.1 - 0.00011 21.9 0.0 0.00016 21.4 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EIE90816.1 - 0.003 17.4 0.1 0.0058 16.4 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EIE90816.1 - 0.0045 17.1 0.1 0.0046 17.1 0.0 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 EIE90816.1 - 0.091 12.8 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2870) Plexin_cytopl PF08337.7 EIE90816.1 - 0.16 10.2 0.7 2.8 6.1 0.3 2.0 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain Fer2_3 PF13085.1 EIE90816.1 - 0.22 11.3 2.0 0.92 9.3 0.9 2.1 1 1 1 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain Ras PF00071.17 EIE90817.1 - 2.5e-48 163.5 0.0 3e-48 163.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIE90817.1 - 1.8e-15 57.4 0.0 3.7e-15 56.4 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EIE90817.1 - 2e-10 40.2 0.0 2.4e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EIE90817.1 - 7.3e-05 22.0 0.0 9e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RNA_helicase PF00910.17 EIE90817.1 - 0.00038 20.5 0.1 0.0026 17.9 0.0 2.1 1 1 0 1 1 1 1 RNA helicase G-alpha PF00503.15 EIE90817.1 - 0.013 14.2 1.9 0.61 8.7 0.0 2.4 2 1 1 3 3 3 0 G-protein alpha subunit Pox_A32 PF04665.7 EIE90817.1 - 0.023 14.0 0.0 0.039 13.2 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_22 PF13401.1 EIE90817.1 - 0.068 13.3 0.1 0.39 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EIE90817.1 - 0.072 12.9 0.1 0.14 11.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EIE90817.1 - 0.16 11.0 0.1 0.25 10.4 0.1 1.2 1 0 0 1 1 1 0 KaiC AAA PF00004.24 EIE90818.1 - 1.5e-05 25.1 0.5 0.00039 20.6 0.3 2.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EIE90818.1 - 0.0012 18.9 0.3 0.0038 17.3 0.2 1.9 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EIE90818.1 - 0.014 14.5 0.0 0.029 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DUF815 PF05673.8 EIE90818.1 - 0.015 14.2 0.1 0.027 13.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Miro PF08477.8 EIE90818.1 - 0.016 15.7 0.3 0.016 15.7 0.2 2.4 2 0 0 2 2 2 0 Miro-like protein AAA_16 PF13191.1 EIE90818.1 - 0.019 14.9 0.0 0.072 13.0 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Arch_ATPase PF01637.13 EIE90818.1 - 0.023 14.3 1.4 0.058 13.0 1.0 1.7 1 0 0 1 1 1 0 Archaeal ATPase Pex16 PF08610.5 EIE90818.1 - 0.051 12.5 5.6 0.15 10.9 3.9 1.8 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) TFIIA PF03153.8 EIE90819.1 - 0.0015 18.4 12.3 0.002 18.0 8.6 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Astro_capsid PF03115.9 EIE90819.1 - 0.005 15.1 3.6 0.0046 15.2 2.5 1.2 1 0 0 1 1 1 1 Astrovirus capsid protein precursor CDC45 PF02724.9 EIE90819.1 - 0.0073 14.4 16.0 0.0088 14.1 11.1 1.1 1 0 0 1 1 1 1 CDC45-like protein Tim54 PF11711.3 EIE90819.1 - 0.052 12.1 9.8 0.096 11.2 6.8 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 FmdE PF02663.9 EIE90819.1 - 0.067 13.0 1.2 0.1 12.5 0.9 1.3 1 0 0 1 1 1 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon IncA PF04156.9 EIE90819.1 - 0.07 12.7 8.5 0.077 12.5 5.9 1.1 1 0 0 1 1 1 0 IncA protein Nop14 PF04147.7 EIE90819.1 - 0.11 10.4 27.4 0.15 9.9 19.0 1.1 1 0 0 1 1 1 0 Nop14-like family BTV_NS2 PF04514.7 EIE90819.1 - 0.25 10.1 16.4 0.33 9.8 11.4 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 SDA1 PF05285.7 EIE90819.1 - 0.95 8.6 26.7 1.2 8.2 18.5 1.1 1 0 0 1 1 1 0 SDA1 RNA_pol_3_Rpc31 PF11705.3 EIE90819.1 - 1.2 9.0 29.6 1.1 9.1 19.7 1.5 1 1 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Spore_coat_CotO PF14153.1 EIE90819.1 - 1.2 8.4 20.9 2.1 7.7 14.5 1.4 1 0 0 1 1 1 0 Spore coat protein CotO PPP4R2 PF09184.6 EIE90819.1 - 1.4 8.3 24.1 2.3 7.6 16.7 1.3 1 0 0 1 1 1 0 PPP4R2 RR_TM4-6 PF06459.7 EIE90819.1 - 1.6 8.5 17.9 2.4 7.9 12.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1510 PF07423.6 EIE90819.1 - 1.6 8.0 24.8 2.4 7.4 17.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Zip PF02535.17 EIE90819.1 - 1.6 7.6 5.3 1.6 7.6 3.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Hid1 PF12722.2 EIE90819.1 - 3.3 5.2 8.8 3.1 5.3 6.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Vfa1 PF08432.5 EIE90819.1 - 3.8 7.5 17.4 6.2 6.8 12.1 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Pox_Ag35 PF03286.9 EIE90819.1 - 4.2 6.8 18.0 7.6 6.0 12.5 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein NOA36 PF06524.7 EIE90819.1 - 4.9 6.3 15.5 6.3 5.9 10.8 1.1 1 0 0 1 1 1 0 NOA36 protein Paf1 PF03985.8 EIE90819.1 - 8.3 5.0 27.3 11 4.6 18.9 1.1 1 0 0 1 1 1 0 Paf1 VID27 PF08553.5 EIE90819.1 - 8.4 4.4 26.9 12 4.0 18.7 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein YL1 PF05764.8 EIE90819.1 - 8.9 5.8 29.4 16 5.0 20.4 1.4 1 0 0 1 1 1 0 YL1 nuclear protein Sigma70_ner PF04546.8 EIE90819.1 - 9.4 5.7 22.0 17 4.9 15.2 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region TRAP_alpha PF03896.11 EIE90819.1 - 9.6 5.1 21.2 13 4.6 14.7 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Mpp10 PF04006.7 EIE90819.1 - 9.7 4.4 31.9 12 4.0 22.1 1.1 1 0 0 1 1 1 0 Mpp10 protein Ycf1 PF05758.7 EIE90819.1 - 10 3.7 16.3 12 3.3 11.3 1.1 1 0 0 1 1 1 0 Ycf1 CLTH PF10607.4 EIE90821.1 - 8.9e-27 93.5 0.4 1.4e-22 79.9 0.1 2.1 1 1 1 2 2 2 2 CTLH/CRA C-terminal to LisH motif domain Lumazine_bd PF12870.2 EIE90821.1 - 0.02 14.9 0.1 5.9 6.9 0.0 2.5 2 1 1 3 3 3 0 Lumazine-binding domain His_biosynth PF00977.16 EIE90822.1 - 2.6e-24 85.7 0.0 4.7e-11 42.3 0.0 2.0 1 1 1 2 2 2 2 Histidine biosynthesis protein Aldolase PF01081.14 EIE90822.1 - 0.15 11.1 0.0 0.26 10.4 0.0 1.3 1 0 0 1 1 1 0 KDPG and KHG aldolase HIT PF01230.18 EIE90823.1 - 1.1e-11 45.1 0.1 1.5e-11 44.7 0.1 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EIE90823.1 - 0.043 14.0 0.0 0.072 13.3 0.0 1.4 1 0 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding MAGE PF01454.14 EIE90824.1 - 2.4e-21 75.9 6.7 2.4e-17 62.9 0.5 2.2 1 1 1 2 2 2 2 MAGE family NUDIX_2 PF13869.1 EIE90824.1 - 0.049 12.9 1.5 0.12 11.6 0.7 1.8 1 1 1 2 2 2 0 Nucleotide hydrolase Hep_59 PF07052.6 EIE90826.1 - 3.5e-29 101.2 4.4 3.5e-29 101.2 3.0 2.8 3 1 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 TAT_signal PF10518.4 EIE90828.1 - 2.7 8.2 6.6 0.68 10.0 1.4 2.2 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence BAR PF03114.13 EIE90829.1 - 1.7e-44 152.0 1.5 1.7e-44 152.0 1.0 1.8 2 0 0 2 2 2 1 BAR domain Ribosomal_L7Ae PF01248.21 EIE90829.1 - 8.3e-25 86.1 0.3 1.9e-24 84.9 0.2 1.7 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family ADH_zinc_N PF00107.21 EIE90829.1 - 3.4e-24 84.8 0.1 1.2e-23 83.1 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIE90829.1 - 0.0024 18.7 0.0 0.0092 16.8 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase RNase_P_pop3 PF08228.6 EIE90829.1 - 0.0031 17.3 0.0 0.0069 16.2 0.0 1.5 1 0 0 1 1 1 1 RNase P subunit Pop3 Arfaptin PF06456.8 EIE90829.1 - 0.012 14.9 3.1 0.032 13.5 2.2 1.7 1 1 0 1 1 1 0 Arfaptin-like domain Glutaredoxin2_C PF04399.8 EIE90829.1 - 0.096 12.2 0.9 7.1 6.2 0.6 2.6 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain AAA_13 PF13166.1 EIE90829.1 - 5.1 5.4 12.5 0.12 10.7 4.2 1.5 2 0 0 2 2 2 0 AAA domain GCIP PF13324.1 EIE90830.1 - 1.9e-21 76.5 0.3 2.6e-21 76.0 0.2 1.1 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting AOX PF01786.12 EIE90831.1 - 4.1e-79 264.7 0.2 5e-79 264.4 0.1 1.0 1 0 0 1 1 1 1 Alternative oxidase DUF3453 PF11935.3 EIE90832.1 - 1.1e-14 54.4 0.5 3.6e-14 52.7 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3453) Ras PF00071.17 EIE90833.1 - 2.2e-35 121.4 0.0 2.5e-35 121.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIE90833.1 - 1.8e-06 28.4 0.0 3.1e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Abhydrolase_2 PF02230.11 EIE90834.1 - 3.6e-09 36.3 0.6 2e-07 30.6 0.0 2.0 1 1 1 2 2 2 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 EIE90834.1 - 5.1e-09 35.6 0.1 6.3e-09 35.3 0.1 1.0 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EIE90834.1 - 1.3e-08 34.6 0.0 1.6e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIE90834.1 - 1.6e-06 28.1 0.0 2.2e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EIE90834.1 - 1.7e-06 27.7 0.0 2.1e-05 24.1 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2305 PF10230.4 EIE90834.1 - 8.2e-05 22.1 0.1 0.00012 21.6 0.0 1.5 1 1 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_1 PF00561.15 EIE90834.1 - 0.0002 20.9 2.6 0.056 12.9 0.4 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Ser_hydrolase PF06821.8 EIE90834.1 - 0.0012 18.4 0.0 0.0016 18.0 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase COesterase PF00135.23 EIE90834.1 - 0.0071 15.1 0.0 0.0071 15.1 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family PGAP1 PF07819.8 EIE90834.1 - 0.0089 15.6 0.1 0.018 14.6 0.0 1.5 2 0 0 2 2 2 1 PGAP1-like protein DLH PF01738.13 EIE90834.1 - 0.027 13.7 0.0 0.11 11.7 0.0 1.8 1 1 0 1 1 1 0 Dienelactone hydrolase family DUF915 PF06028.6 EIE90834.1 - 0.033 13.2 0.1 0.2 10.7 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.15 EIE90834.1 - 0.057 12.8 0.0 0.071 12.5 0.0 1.3 1 0 0 1 1 1 0 Putative esterase BAAT_C PF08840.6 EIE90834.1 - 0.064 12.9 0.0 0.11 12.2 0.0 1.5 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF3089 PF11288.3 EIE90834.1 - 0.076 12.1 0.1 0.15 11.2 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3089) Lipase_3 PF01764.20 EIE90834.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) HMG_box PF00505.14 EIE90835.1 - 6.4e-18 64.7 0.7 1.3e-17 63.8 0.5 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EIE90835.1 - 1e-12 48.2 0.6 2.1e-12 47.1 0.4 1.6 1 0 0 1 1 1 1 HMG-box domain Tol_Tol_Ttg2 PF05494.7 EIE90835.1 - 0.019 14.5 0.1 0.03 13.8 0.1 1.4 1 0 0 1 1 1 0 Toluene tolerance, Ttg2 NDUFB10 PF10249.4 EIE90835.1 - 0.027 14.6 0.3 0.04 14.0 0.2 1.3 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit 10 RNA_pol_Rpc4 PF05132.9 EIE90836.1 - 1e-30 106.4 5.9 1.4e-30 105.9 0.4 2.2 2 0 0 2 2 2 2 RNA polymerase III RPC4 TBP PF00352.16 EIE90838.1 - 3.1e-69 228.3 0.1 7.5e-35 118.1 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 EIE90838.1 - 0.00017 21.5 0.1 0.68 10.0 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) Ribosomal_L37 PF08561.5 EIE90839.1 - 2.1e-25 88.0 2.2 2.6e-25 87.8 1.5 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 FAD_binding_1 PF00667.15 EIE90840.1 - 1.3e-43 148.9 0.0 2.8e-43 147.9 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain Flavodoxin_1 PF00258.20 EIE90840.1 - 2.9e-29 101.9 1.3 5.8e-29 100.9 0.1 2.2 3 0 0 3 3 3 1 Flavodoxin NAD_binding_1 PF00175.16 EIE90840.1 - 4.7e-19 68.9 0.0 2e-18 66.9 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_3 PF12641.2 EIE90840.1 - 0.0022 17.4 0.0 0.0041 16.5 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin domain Glyoxalase_2 PF12681.2 EIE90841.1 - 7.4e-08 32.9 0.0 8.4e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 EIE90841.1 - 3.4e-05 23.8 0.0 4.2e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily AAA_2 PF07724.9 EIE90842.1 - 6.5e-57 192.1 0.5 6.2e-52 175.9 0.0 3.3 3 0 0 3 3 3 2 AAA domain (Cdc48 subfamily) AAA PF00004.24 EIE90842.1 - 8.4e-28 97.1 0.0 1.2e-14 54.6 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 EIE90842.1 - 1.7e-23 82.2 2.3 4.9e-23 80.8 0.1 3.0 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 EIE90842.1 - 2.6e-20 72.5 1.2 5.2e-11 42.4 0.0 4.2 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EIE90842.1 - 2.6e-14 53.6 3.1 4.3e-06 26.8 0.0 4.9 4 2 1 6 6 4 2 AAA ATPase domain Clp_N PF02861.15 EIE90842.1 - 1.5e-11 43.9 0.1 2.5e-09 36.9 0.1 3.0 2 0 0 2 2 2 1 Clp amino terminal domain AAA_22 PF13401.1 EIE90842.1 - 3.1e-10 40.3 0.1 0.0017 18.4 0.0 4.2 3 2 0 3 3 3 2 AAA domain Sigma54_activat PF00158.21 EIE90842.1 - 1.3e-09 37.7 0.0 3.2e-06 26.7 0.0 2.8 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_14 PF13173.1 EIE90842.1 - 5.3e-08 32.8 0.1 0.012 15.5 0.0 3.6 3 2 0 3 3 2 2 AAA domain AAA_17 PF13207.1 EIE90842.1 - 4.4e-07 30.7 7.6 0.018 15.8 0.0 4.1 4 2 0 4 4 3 2 AAA domain Mg_chelatase PF01078.16 EIE90842.1 - 5.2e-07 29.0 0.0 0.029 13.5 0.1 3.5 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 EIE90842.1 - 5.5e-07 29.1 0.0 0.039 13.3 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_19 PF13245.1 EIE90842.1 - 3.9e-05 23.3 0.0 0.036 13.8 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain AAA_18 PF13238.1 EIE90842.1 - 6.6e-05 23.2 7.8 0.015 15.5 0.0 3.9 4 1 0 4 4 2 2 AAA domain MobB PF03205.9 EIE90842.1 - 7.6e-05 22.4 0.0 0.078 12.6 0.0 2.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 EIE90842.1 - 0.00012 21.7 0.0 0.033 13.8 0.0 2.7 2 0 0 2 2 2 1 NACHT domain RNA_helicase PF00910.17 EIE90842.1 - 0.00021 21.4 0.0 0.86 9.8 0.0 2.9 3 0 0 3 3 2 2 RNA helicase Torsin PF06309.6 EIE90842.1 - 0.00032 20.5 0.0 0.00094 19.0 0.0 1.7 1 0 0 1 1 1 1 Torsin ABC_tran PF00005.22 EIE90842.1 - 0.00062 20.0 0.5 0.4 10.9 0.0 3.6 3 1 0 3 3 3 1 ABC transporter AAA_28 PF13521.1 EIE90842.1 - 0.0011 18.9 0.1 3.3 7.6 0.0 3.7 3 0 0 3 3 3 1 AAA domain Arch_ATPase PF01637.13 EIE90842.1 - 0.0018 18.0 10.4 0.14 11.8 0.0 4.8 3 2 1 4 4 4 1 Archaeal ATPase AAA_24 PF13479.1 EIE90842.1 - 0.002 17.7 0.0 0.25 10.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 EIE90842.1 - 0.0023 17.7 0.1 0.37 10.5 0.0 3.7 2 2 0 4 4 3 1 Type III restriction enzyme, res subunit DUF258 PF03193.11 EIE90842.1 - 0.0046 16.1 0.0 2.3 7.3 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EIE90842.1 - 0.005 16.7 0.0 0.7 9.8 0.0 3.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_25 PF13481.1 EIE90842.1 - 0.005 16.2 0.1 2.1 7.7 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_3 PF07726.6 EIE90842.1 - 0.005 16.4 0.0 2.1 7.9 0.0 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.17 EIE90842.1 - 0.011 15.2 0.0 1.1 8.6 0.0 2.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_10 PF12846.2 EIE90842.1 - 0.014 14.8 4.0 1 8.7 0.0 3.8 3 2 0 3 3 3 0 AAA-like domain NTPase_1 PF03266.10 EIE90842.1 - 0.014 15.1 0.0 4.8 6.8 0.0 3.6 3 0 0 3 3 3 0 NTPase AAA_33 PF13671.1 EIE90842.1 - 0.018 14.9 0.3 4.7 7.0 0.0 3.5 4 0 0 4 4 3 0 AAA domain BLOC1_2 PF10046.4 EIE90842.1 - 0.02 14.9 6.5 0.022 14.8 2.8 2.4 2 0 0 2 2 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ATP_bind_1 PF03029.12 EIE90842.1 - 0.023 14.2 0.0 1.2 8.6 0.0 3.1 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.4 EIE90842.1 - 0.024 14.1 0.0 1.6 8.2 0.0 2.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF458 PF04308.7 EIE90842.1 - 0.06 13.0 0.1 0.18 11.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF458) UPF0079 PF02367.12 EIE90842.1 - 0.066 12.8 0.0 18 5.0 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Fmp27_WPPW PF10359.4 EIE90842.1 - 0.087 11.2 6.7 0.15 10.4 4.7 1.3 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain AAA_29 PF13555.1 EIE90842.1 - 0.15 11.6 0.0 7.6 6.1 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain IncA PF04156.9 EIE90842.1 - 0.2 11.2 17.1 0.16 11.5 9.9 2.2 2 1 0 2 2 1 0 IncA protein DUF1192 PF06698.6 EIE90842.1 - 0.4 10.5 12.5 0.62 9.9 0.1 4.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) HGD-D PF06050.8 EIE90842.1 - 0.47 9.2 3.7 7.9 5.1 0.0 3.5 4 0 0 4 4 4 0 2-hydroxyglutaryl-CoA dehydratase, D-component Cob_adeno_trans PF01923.13 EIE90842.1 - 0.62 9.8 5.1 9.5 5.9 1.7 3.2 2 1 1 3 3 3 0 Cobalamin adenosyltransferase AAA_23 PF13476.1 EIE90842.1 - 2.4 8.4 23.3 0.037 14.3 1.3 4.6 4 1 0 4 4 4 0 AAA domain Viral_P18 PF04521.8 EIE90842.1 - 4.7 6.6 5.9 22 4.5 0.8 2.6 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein V_ATPase_I PF01496.14 EIE90842.1 - 5.8 4.6 5.1 9.7 3.8 3.5 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2040 PF09745.4 EIE90843.1 - 6.2e-35 119.8 24.0 6.2e-35 119.8 16.6 3.9 3 2 1 4 4 4 1 Coiled-coil domain-containing protein 55 (DUF2040) cNMP_binding PF00027.24 EIE90844.1 - 2e-35 120.4 0.4 1.4e-20 72.8 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.12 EIE90844.1 - 1.7e-06 27.3 0.1 3.8e-06 26.2 0.1 1.6 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Taeniidae_ag PF05596.6 EIE90845.1 - 0.13 12.0 0.0 0.14 12.0 0.0 1.1 1 0 0 1 1 1 0 Taeniidae antigen NUDIX PF00293.23 EIE90846.1 - 2.5e-19 69.2 0.8 3.5e-19 68.7 0.6 1.2 1 0 0 1 1 1 1 NUDIX domain BRF1 PF07741.8 EIE90846.1 - 1.7 8.8 5.7 1.6 8.9 2.7 1.9 1 1 1 2 2 2 0 Brf1-like TBP-binding domain Tropomyosin_1 PF12718.2 EIE90847.1 - 4.4e-16 59.0 29.5 2.5e-11 43.5 7.4 2.1 1 1 1 2 2 2 2 Tropomyosin like Tropomyosin PF00261.15 EIE90847.1 - 1.9e-06 27.1 26.2 2.7e-06 26.6 18.2 1.2 1 0 0 1 1 1 1 Tropomyosin DUF948 PF06103.6 EIE90847.1 - 0.00016 21.4 2.3 0.00016 21.4 1.6 2.3 1 1 2 3 3 3 1 Bacterial protein of unknown function (DUF948) KLRAQ PF10205.4 EIE90847.1 - 0.00036 20.5 12.3 0.00069 19.6 3.3 2.1 1 1 1 2 2 2 1 Predicted coiled-coil domain-containing protein Flagellin_C PF00700.16 EIE90847.1 - 0.00071 19.6 3.6 0.00071 19.6 2.5 2.2 2 1 1 3 3 2 1 Bacterial flagellin C-terminal helical region CENP-F_leu_zip PF10473.4 EIE90847.1 - 0.0011 18.8 25.8 0.059 13.2 8.8 2.1 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Occludin_ELL PF07303.8 EIE90847.1 - 0.0028 18.3 9.1 0.0034 18.0 4.2 2.3 1 1 1 2 2 2 1 Occludin homology domain ATG16 PF08614.6 EIE90847.1 - 0.0029 17.4 21.3 0.0089 15.8 14.7 1.7 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) MscS_porin PF12795.2 EIE90847.1 - 0.0052 16.1 24.5 0.016 14.5 17.2 1.5 1 1 0 1 1 1 1 Mechanosensitive ion channel porin domain FliD_C PF07195.7 EIE90847.1 - 0.0054 16.0 13.3 0.14 11.3 2.9 2.1 1 1 1 2 2 2 2 Flagellar hook-associated protein 2 C-terminus APG6 PF04111.7 EIE90847.1 - 0.0085 15.1 22.5 0.0099 14.9 15.6 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 WXG100 PF06013.7 EIE90847.1 - 0.013 15.5 16.7 1.1 9.2 0.7 3.3 2 1 0 2 2 2 0 Proteins of 100 residues with WXG GAS PF13851.1 EIE90847.1 - 0.013 14.6 22.8 0.019 14.1 13.2 1.8 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Myosin_tail_1 PF01576.14 EIE90847.1 - 0.015 13.0 25.1 0.017 12.8 17.4 1.0 1 0 0 1 1 1 0 Myosin tail ADIP PF11559.3 EIE90847.1 - 0.017 15.0 22.6 0.45 10.4 11.5 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF869 PF05911.6 EIE90847.1 - 0.018 13.3 18.4 0.021 13.0 12.8 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) Tup_N PF08581.5 EIE90847.1 - 0.019 15.1 13.1 0.022 14.9 3.1 2.3 1 1 0 2 2 2 0 Tup N-terminal Spc7 PF08317.6 EIE90847.1 - 0.02 13.5 20.8 0.017 13.8 6.0 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF3450 PF11932.3 EIE90847.1 - 0.02 14.1 19.5 0.13 11.5 4.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) WEMBL PF05701.6 EIE90847.1 - 0.021 13.2 29.6 0.026 13.0 20.5 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light HalX PF08663.5 EIE90847.1 - 0.026 14.5 19.6 0.34 10.9 4.5 3.4 2 1 1 3 3 3 0 HalX domain Uds1 PF15456.1 EIE90847.1 - 0.026 14.5 16.4 0.25 11.3 10.0 2.0 2 0 0 2 2 2 0 Up-regulated During Septation Laminin_I PF06008.9 EIE90847.1 - 0.041 13.1 18.1 0.11 11.7 12.5 1.7 1 1 0 1 1 1 0 Laminin Domain I DUF3584 PF12128.3 EIE90847.1 - 0.047 11.0 20.7 0.055 10.8 14.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Nup54 PF13874.1 EIE90847.1 - 0.047 13.3 15.4 0.037 13.6 7.0 2.0 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Snapin_Pallidin PF14712.1 EIE90847.1 - 0.053 13.8 11.6 0.26 11.6 0.1 2.6 1 1 1 2 2 2 0 Snapin/Pallidin Syntaxin PF00804.20 EIE90847.1 - 0.06 13.5 14.6 0.58 10.3 6.1 2.1 1 1 1 2 2 2 0 Syntaxin Reo_sigmaC PF04582.7 EIE90847.1 - 0.062 12.4 1.3 0.078 12.1 0.9 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Filament PF00038.16 EIE90847.1 - 0.071 12.5 19.7 0.21 10.9 13.7 1.7 1 1 0 1 1 1 0 Intermediate filament protein Prefoldin_2 PF01920.15 EIE90847.1 - 0.08 12.7 25.8 0.07 12.8 3.6 3.1 1 1 2 3 3 3 0 Prefoldin subunit TMF_DNA_bd PF12329.3 EIE90847.1 - 0.1 12.4 30.7 0.74 9.6 3.6 2.9 1 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding FlaC_arch PF05377.6 EIE90847.1 - 0.11 12.3 11.5 1.5 8.7 0.2 3.7 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) Nsp1_C PF05064.8 EIE90847.1 - 0.15 11.7 15.4 0.065 12.8 4.2 2.2 1 1 1 2 2 2 0 Nsp1-like C-terminal region Atg14 PF10186.4 EIE90847.1 - 0.17 10.7 17.1 0.16 10.8 10.7 1.7 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4201 PF13870.1 EIE90847.1 - 0.18 11.2 16.9 0.83 9.0 10.2 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) V-ATPase_C PF03223.10 EIE90847.1 - 0.2 10.5 7.9 0.24 10.2 5.4 1.1 1 0 0 1 1 1 0 V-ATPase subunit C DUF812 PF05667.6 EIE90847.1 - 0.22 10.0 17.1 0.33 9.3 11.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) IZUMO PF15005.1 EIE90847.1 - 0.25 11.3 5.6 0.28 11.1 3.9 1.2 1 0 0 1 1 1 0 Izumo sperm-egg fusion Transposase_22 PF02994.9 EIE90847.1 - 0.26 9.7 12.5 0.32 9.4 8.6 1.2 1 0 0 1 1 1 0 L1 transposable element RmuC PF02646.11 EIE90847.1 - 0.26 10.0 10.8 0.24 10.2 5.9 2.0 1 1 2 3 3 3 0 RmuC family Mnd1 PF03962.10 EIE90847.1 - 0.29 10.7 21.7 1.1 8.8 15.1 1.8 1 1 0 1 1 1 0 Mnd1 family Tektin PF03148.9 EIE90847.1 - 0.31 9.5 20.3 11 4.4 14.0 2.0 1 1 0 1 1 1 0 Tektin family AAA_13 PF13166.1 EIE90847.1 - 0.36 9.2 18.5 0.6 8.5 12.8 1.4 1 1 0 1 1 1 0 AAA domain Laminin_II PF06009.7 EIE90847.1 - 0.38 10.5 11.5 0.53 10.0 7.4 1.7 1 1 1 2 2 2 0 Laminin Domain II DUF4200 PF13863.1 EIE90847.1 - 0.4 10.6 26.3 0.49 10.3 7.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) TPR_MLP1_2 PF07926.7 EIE90847.1 - 0.4 10.4 27.3 2.3 7.9 10.1 2.5 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein GrpE PF01025.14 EIE90847.1 - 0.4 10.1 26.1 0.33 10.4 3.3 3.0 1 1 2 3 3 3 0 GrpE DUF208 PF02677.9 EIE90847.1 - 0.49 10.1 2.5 0.6 9.8 1.7 1.3 1 0 0 1 1 1 0 Uncharacterized BCR, COG1636 TBPIP PF07106.8 EIE90847.1 - 0.5 9.9 18.4 0.81 9.2 8.3 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Seryl_tRNA_N PF02403.17 EIE90847.1 - 0.56 10.2 24.2 0.99 9.4 8.6 2.5 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain IncA PF04156.9 EIE90847.1 - 0.57 9.7 23.3 1.6 8.3 16.2 1.6 1 1 0 1 1 1 0 IncA protein DUF4337 PF14235.1 EIE90847.1 - 0.58 9.9 25.8 2.6 7.8 8.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) Fib_alpha PF08702.5 EIE90847.1 - 0.59 10.2 11.3 2.2 8.4 7.1 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF724 PF05266.9 EIE90847.1 - 0.65 9.5 20.8 0.41 10.2 5.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Lebercilin PF15619.1 EIE90847.1 - 0.65 9.3 22.9 1.6 8.1 15.9 1.7 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease AAA_27 PF13514.1 EIE90847.1 - 0.66 7.5 22.7 2.2 5.8 15.8 1.4 1 1 0 1 1 1 0 AAA domain DUF641 PF04859.7 EIE90847.1 - 0.79 9.4 16.6 0.17 11.6 6.9 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Fmp27_WPPW PF10359.4 EIE90847.1 - 0.86 7.9 14.2 2.1 6.6 9.9 1.6 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Striatin PF08232.7 EIE90847.1 - 0.97 9.7 14.8 1.4 9.2 10.2 1.4 1 1 0 1 1 1 0 Striatin family DUF1664 PF07889.7 EIE90847.1 - 0.98 9.2 8.1 1.3 8.7 0.8 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Use1 PF09753.4 EIE90847.1 - 0.99 8.7 11.7 1.2 8.5 8.1 1.1 1 0 0 1 1 1 0 Membrane fusion protein Use1 Peptidase_S15 PF02129.13 EIE90847.1 - 1.1 8.6 3.4 1.2 8.5 2.3 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF972 PF06156.8 EIE90847.1 - 1.2 9.5 17.0 2.8 8.3 5.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Syntaxin-6_N PF09177.6 EIE90847.1 - 1.2 9.5 13.7 12 6.3 1.2 2.4 1 1 1 2 2 2 0 Syntaxin 6, N-terminal TEX12 PF15219.1 EIE90847.1 - 1.2 9.1 6.3 1.3 9.0 3.2 1.8 1 1 1 2 2 2 0 Testis-expressed 12 ERM PF00769.14 EIE90847.1 - 1.8 8.0 28.5 7.9 5.9 19.8 1.9 1 1 0 1 1 1 0 Ezrin/radixin/moesin family CDC37_N PF03234.9 EIE90847.1 - 1.8 8.8 17.2 6.4 7.0 11.9 1.7 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding DUF3552 PF12072.3 EIE90847.1 - 2 7.5 24.6 14 4.7 16.7 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) PilJ PF13675.1 EIE90847.1 - 2.1 8.6 10.8 3.5 7.9 4.0 2.2 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term MtrG PF04210.8 EIE90847.1 - 2.2 8.0 6.8 23 4.7 0.1 3.7 1 1 3 4 4 4 0 Tetrahydromethanopterin S-methyltransferase, subunit G DUF2968 PF11180.3 EIE90847.1 - 2.3 7.5 20.2 5.1 6.4 6.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) BLOC1_2 PF10046.4 EIE90847.1 - 2.6 8.2 14.6 9.5 6.4 5.4 2.5 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FH2 PF02181.18 EIE90847.1 - 2.6 6.8 14.2 0.23 10.2 4.0 1.9 1 1 1 2 2 2 0 Formin Homology 2 Domain DUF904 PF06005.7 EIE90847.1 - 2.6 8.3 25.4 1.1 9.6 4.0 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF904) Exonuc_VII_L PF02601.10 EIE90847.1 - 2.6 7.1 13.4 3 6.9 9.3 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Phlebovirus_NSM PF07246.6 EIE90847.1 - 2.7 7.0 11.5 3 6.9 7.9 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Spc24 PF08286.6 EIE90847.1 - 2.8 7.6 19.4 2.3 7.9 1.7 2.6 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Cortex-I_coil PF09304.5 EIE90847.1 - 2.9 7.9 21.9 1.9 8.5 7.2 2.5 1 1 1 2 2 2 0 Cortexillin I, coiled coil Allexi_40kDa PF05549.6 EIE90847.1 - 3.5 6.8 6.6 4.9 6.3 4.5 1.4 1 1 0 1 1 1 0 Allexivirus 40kDa protein bZIP_1 PF00170.16 EIE90847.1 - 3.6 7.6 22.0 1.1 9.2 4.3 3.6 2 2 1 3 3 3 0 bZIP transcription factor DivIC PF04977.10 EIE90847.1 - 3.7 7.0 25.9 7.6 6.1 3.3 3.3 1 1 2 3 3 3 0 Septum formation initiator EMP24_GP25L PF01105.19 EIE90847.1 - 4.4 6.9 10.2 3.9 7.1 4.9 2.3 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD Bacillus_HBL PF05791.6 EIE90847.1 - 4.4 6.6 12.6 34 3.7 8.7 2.0 1 1 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) DUF2681 PF10883.3 EIE90847.1 - 4.9 7.4 17.0 3.1 8.0 3.8 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF2681) DUF4472 PF14739.1 EIE90847.1 - 5.3 7.5 15.6 8.9 6.8 7.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) Viral_P18 PF04521.8 EIE90847.1 - 5.6 6.4 16.8 4.9 6.6 4.1 2.7 1 1 2 3 3 3 0 ssRNA positive strand viral 18kD cysteine rich protein MAD PF05557.8 EIE90847.1 - 5.9 4.8 22.6 9.6 4.1 15.6 1.4 1 1 0 1 1 1 0 Mitotic checkpoint protein FUSC PF04632.7 EIE90847.1 - 5.9 5.1 8.2 5.9 5.1 5.7 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Ax_dynein_light PF10211.4 EIE90847.1 - 6 6.6 22.7 6.9 6.4 2.5 2.6 1 1 2 3 3 3 0 Axonemal dynein light chain U1snRNP70_N PF12220.3 EIE90847.1 - 6.5 7.1 10.5 1.6 9.1 4.1 2.1 1 1 1 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal NPV_P10 PF05531.7 EIE90847.1 - 6.5 7.0 9.1 76 3.6 0.2 2.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein TMPIT PF07851.8 EIE90847.1 - 7 5.6 9.3 8.7 5.3 6.5 1.3 1 0 0 1 1 1 0 TMPIT-like protein TMCO5 PF14992.1 EIE90847.1 - 7.2 5.6 17.6 10 5.1 3.8 2.0 1 1 1 2 2 2 0 TMCO5 family Lectin_N PF03954.9 EIE90847.1 - 7.8 5.8 7.8 5.7 6.3 3.0 2.0 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain OmpH PF03938.9 EIE90847.1 - 8.7 6.2 30.5 1.2e+02 2.6 19.4 2.0 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) CENP-Q PF13094.1 EIE90847.1 - 9.1 6.2 27.8 15 5.5 14.8 2.1 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit PV-1 PF06637.6 EIE90847.1 - 9.5 4.6 18.0 13 4.2 12.5 1.1 1 0 0 1 1 1 0 PV-1 protein (PLVAP) V_ATPase_I PF01496.14 EIE90847.1 - 9.5 3.9 15.5 16 3.1 10.8 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family KxDL PF10241.4 EIE90847.1 - 9.6 6.1 9.4 12 5.8 3.8 2.5 1 1 2 3 3 3 0 Uncharacterized conserved protein HlyD PF00529.15 EIE90847.1 - 9.8 5.3 22.0 13 4.9 15.3 1.1 1 0 0 1 1 1 0 HlyD family secretion protein TIP49 PF06068.8 EIE90848.1 - 2e-190 632.7 0.8 2.3e-190 632.4 0.5 1.0 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 EIE90848.1 - 8.4e-11 41.3 2.4 1.2e-06 27.7 0.0 3.1 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 EIE90848.1 - 1.1e-10 41.8 1.0 1.2e-06 28.7 0.0 2.7 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EIE90848.1 - 1e-07 32.1 0.0 0.013 15.5 0.0 2.8 3 0 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 EIE90848.1 - 1.4e-05 25.2 0.0 0.077 13.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 EIE90848.1 - 0.0022 17.2 0.1 0.066 12.3 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EIE90848.1 - 0.0027 17.4 0.0 0.31 10.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EIE90848.1 - 0.0031 17.2 0.0 0.0068 16.1 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 EIE90848.1 - 0.0031 16.9 0.0 0.0057 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 EIE90848.1 - 0.0058 16.1 0.1 2.8 7.3 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_18 PF13238.1 EIE90848.1 - 0.007 16.6 0.0 0.029 14.6 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EIE90848.1 - 0.011 15.6 0.0 0.029 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EIE90848.1 - 0.014 15.2 0.0 0.46 10.3 0.0 2.5 2 1 0 2 2 2 0 AAA domain DUF2075 PF09848.4 EIE90848.1 - 0.025 13.5 0.0 0.043 12.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 EIE90848.1 - 0.029 14.1 0.7 0.51 10.1 0.0 2.3 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit IstB_IS21 PF01695.12 EIE90848.1 - 0.037 13.4 0.1 0.076 12.4 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_17 PF13207.1 EIE90848.1 - 0.044 14.6 0.0 0.13 13.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EIE90848.1 - 0.045 12.8 0.1 0.1 11.6 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin Parvo_NS1 PF01057.12 EIE90848.1 - 0.12 11.2 0.0 0.21 10.4 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Reticulon PF02453.12 EIE90849.1 - 3.1e-19 69.2 2.9 4.7e-19 68.6 2.0 1.2 1 0 0 1 1 1 1 Reticulon Pkinase PF00069.20 EIE90850.1 - 5.9e-69 232.1 0.4 5.9e-69 232.1 0.3 2.1 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE90850.1 - 2.8e-34 118.3 0.1 2.8e-32 111.8 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 EIE90850.1 - 1.5e-06 27.4 0.5 3.2e-06 26.3 0.4 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EIE90850.1 - 0.00011 21.2 0.0 0.00037 19.5 0.0 1.7 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 EIE90850.1 - 0.00045 20.0 1.9 0.026 14.2 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 EIE90850.1 - 0.018 14.6 0.4 0.018 14.6 0.3 2.1 2 0 0 2 2 2 0 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.4 EIE90850.1 - 0.14 11.4 2.6 0.59 9.4 1.9 2.0 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL tRNA-synt_1 PF00133.17 EIE90851.1 - 1.2e-129 433.1 15.9 1.7e-111 373.1 0.2 3.5 2 1 1 3 3 3 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EIE90851.1 - 1.6e-32 112.4 2.9 4.3e-32 111.0 2.0 1.8 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EIE90851.1 - 1.3e-13 50.3 0.1 1.5e-11 43.6 0.0 3.0 2 1 0 2 2 2 1 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 EIE90851.1 - 8.1e-05 22.0 0.1 0.00056 19.2 0.0 2.3 2 0 0 2 2 2 1 Leucyl-tRNA synthetase, Domain 2 TrbI_Ftype PF09677.5 EIE90851.1 - 0.1 12.4 5.5 1.7 8.4 0.2 2.7 2 0 0 2 2 2 0 Type-F conjugative transfer system protein (TrbI_Ftype) PRANC PF09372.5 EIE90851.1 - 0.26 11.3 0.1 0.26 11.3 0.1 3.7 4 0 0 4 4 4 0 PRANC domain NAD_binding_4 PF07993.7 EIE90852.1 - 6.4e-40 136.6 0.0 1.9e-39 135.0 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EIE90852.1 - 6.6e-05 22.4 0.7 0.00052 19.5 0.5 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Acyltransferase PF01553.16 EIE90852.1 - 0.00018 20.9 0.0 0.00038 19.8 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase Sterile PF03015.14 EIE90852.1 - 0.0056 16.9 0.0 0.037 14.2 0.0 2.5 1 0 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 EIE90852.1 - 0.16 10.6 4.8 0.21 10.2 0.5 2.7 2 1 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Hydrolase_6 PF13344.1 EIE90852.1 - 2.5 8.0 4.9 1.4 8.8 0.2 2.9 3 1 0 3 3 3 0 Haloacid dehalogenase-like hydrolase NuA4 PF09340.5 EIE90853.1 - 3.3e-26 90.7 0.5 3.3e-26 90.7 0.4 2.1 2 1 0 2 2 2 1 Histone acetyltransferase subunit NuA4 TMEM171 PF15471.1 EIE90853.1 - 0.014 14.2 0.3 0.02 13.7 0.2 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 zf-CpG_bind_C PF12269.3 EIE90853.1 - 0.11 11.9 0.5 4.8 6.5 0.0 2.0 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain PASTA PF03793.14 EIE90853.1 - 0.11 12.1 0.0 0.3 10.7 0.0 1.7 1 0 0 1 1 1 0 PASTA domain Biotin_lipoyl_2 PF13533.1 EIE90853.1 - 0.52 10.0 2.6 0.56 9.9 0.1 2.1 2 0 0 2 2 2 0 Biotin-lipoyl like TTL PF03133.10 EIE90854.1 - 1e-37 129.6 3.4 1e-37 129.6 2.4 2.0 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family DUF3435 PF11917.3 EIE90854.1 - 0.015 14.0 3.9 0.032 12.9 2.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) FAR1 PF03101.10 EIE90855.1 - 2.9e-08 34.1 2.1 1.2e-07 32.1 1.5 2.1 1 1 0 1 1 1 1 FAR1 DNA-binding domain DBD_Tnp_Mut PF03108.10 EIE90855.1 - 2.3e-07 30.2 1.6 3.5e-05 23.2 0.0 2.3 2 0 0 2 2 2 2 MuDR family transposase NAD_binding_7 PF13241.1 EIE90855.1 - 0.16 12.2 4.3 0.15 12.3 1.2 2.2 4 0 0 4 4 4 0 Putative NAD(P)-binding eIF-5_eIF-2B PF01873.12 EIE90856.1 - 9.4e-46 154.5 0.7 1.4e-45 153.9 0.5 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.7 EIE90856.1 - 0.0027 16.9 0.4 0.0058 15.9 0.3 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding SART-1 PF03343.8 EIE90856.1 - 0.036 12.4 30.9 0.053 11.8 21.4 1.3 1 0 0 1 1 1 0 SART-1 family zf-HYPF PF07503.7 EIE90856.1 - 0.1 12.0 0.2 14 5.1 0.0 2.4 2 0 0 2 2 2 0 HypF finger TATR PF03430.8 EIE90856.1 - 0.36 9.4 12.3 0.51 8.9 8.5 1.2 1 0 0 1 1 1 0 Trans-activating transcriptional regulator LRR_6 PF13516.1 EIE90857.1 - 6.8e-14 50.3 8.7 1.2 9.4 0.0 9.9 9 2 2 11 11 11 5 Leucine Rich repeat F-box-like PF12937.2 EIE90857.1 - 2.1e-09 36.9 0.6 2.1e-09 36.9 0.4 2.9 3 0 0 3 3 3 1 F-box-like LRR_4 PF12799.2 EIE90857.1 - 4.5e-08 32.5 1.1 2.3 7.9 0.0 6.2 4 2 0 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EIE90857.1 - 0.00031 20.4 13.8 0.017 14.8 0.2 5.5 4 2 2 6 6 6 3 Leucine rich repeat LRR_7 PF13504.1 EIE90857.1 - 1.7 9.1 18.3 37 5.1 0.1 8.0 10 0 0 10 10 10 0 Leucine rich repeat DUF3357 PF11837.3 EIE90859.1 - 0.00066 19.5 0.0 0.0013 18.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3357) DUF4448 PF14610.1 EIE90859.1 - 0.0032 17.0 0.0 0.0057 16.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF4381 PF14316.1 EIE90859.1 - 0.1 12.6 0.2 0.17 11.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) rve PF00665.21 EIE90862.1 - 3.2e-23 82.1 0.0 7.5e-23 80.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE90862.1 - 7.6e-16 58.1 0.3 2.1e-15 56.6 0.2 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE90862.1 - 4e-11 42.3 1.1 9.6e-11 41.1 0.7 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.12 EIE90862.1 - 0.00068 19.6 1.2 0.0031 17.5 0.8 2.2 1 0 0 1 1 1 1 Retrotransposon gag protein zf-H2C2 PF09337.5 EIE90862.1 - 0.0015 17.9 0.1 0.0041 16.4 0.1 1.8 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Asp_protease_2 PF13650.1 EIE90862.1 - 0.0041 17.5 0.2 0.011 16.2 0.2 1.8 1 0 0 1 1 1 1 Aspartyl protease rve_3 PF13683.1 EIE90862.1 - 0.0073 15.8 0.1 0.05 13.1 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain DUF2246 PF10229.4 EIE90862.1 - 0.0074 15.6 0.8 0.039 13.2 0.1 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2246) UBN2_2 PF14227.1 EIE90862.1 - 0.0097 15.4 4.9 0.036 13.6 0.0 3.4 3 0 0 3 3 3 1 gag-polypeptide of LTR copia-type Asp_protease PF09668.5 EIE90862.1 - 0.043 13.3 0.1 0.13 11.8 0.1 1.8 1 1 0 1 1 1 0 Aspartyl protease zf-CCHC PF00098.18 EIE90863.1 - 0.0039 17.0 1.3 0.0039 17.0 0.9 2.6 2 1 0 2 2 2 1 Zinc knuckle Macin PF14865.1 EIE90863.1 - 0.23 11.5 3.6 1.7 8.7 2.6 2.2 1 1 1 2 2 2 0 Macin HTH_Tnp_Tc3_2 PF01498.13 EIE90864.1 - 5.1e-14 52.0 2.1 5.1e-14 52.0 1.4 1.5 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.1 EIE90864.1 - 0.01 15.5 0.1 0.021 14.5 0.0 1.5 2 0 0 2 2 2 0 DDE superfamily endonuclease Mto2_bdg PF12808.2 EIE90866.1 - 0.017 15.2 1.9 0.68 10.0 0.5 2.6 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region HTH_Tnp_Tc3_2 PF01498.13 EIE90868.1 - 3.5e-17 62.2 1.4 3.5e-17 62.2 1.0 2.5 2 1 1 3 3 3 1 Transposase DDE_3 PF13358.1 EIE90868.1 - 1.5e-12 47.4 0.0 3e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 EIE90868.1 - 5.6e-05 23.2 1.3 0.00021 21.4 0.6 2.1 2 1 0 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.1 EIE90868.1 - 0.0013 18.3 0.3 0.089 12.4 0.0 3.3 3 0 0 3 3 3 1 Homeodomain-like domain HTH_32 PF13565.1 EIE90868.1 - 0.0032 18.2 5.5 0.0081 16.9 0.2 3.5 3 1 1 4 4 4 1 Homeodomain-like domain Transposase_21 PF02992.9 EIE90869.1 - 3.3e-23 81.9 0.1 3.3e-23 81.9 0.1 1.7 2 0 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.1 EIE90869.1 - 1.9e-05 24.0 0.3 4.1e-05 23.0 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) DDE_3 PF13358.1 EIE90871.1 - 4.1e-14 52.5 0.3 9.1e-14 51.4 0.1 1.6 1 1 1 2 2 2 1 DDE superfamily endonuclease rve PF00665.21 EIE90871.1 - 6.2e-05 23.0 0.1 0.00019 21.5 0.0 1.8 2 1 0 2 2 2 1 Integrase core domain DUF2284 PF10050.4 EIE90871.1 - 0.0096 15.5 0.2 0.016 14.8 0.1 1.3 1 0 0 1 1 1 1 Predicted metal-binding protein (DUF2284) HTH_Tnp_Tc3_2 PF01498.13 EIE90872.1 - 0.0022 18.0 0.1 0.0027 17.7 0.1 1.1 1 0 0 1 1 1 1 Transposase SPOR PF05036.8 EIE90872.1 - 0.061 13.4 0.1 3.2 7.9 0.0 2.0 1 1 1 2 2 2 0 Sporulation related domain RVT_1 PF00078.22 EIE90874.1 - 1.7e-16 60.2 0.1 3.7e-16 59.1 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 EIE90874.1 - 8.6e-08 32.5 0.0 2.4e-07 31.1 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 EIE90874.1 - 3.2e-07 30.2 0.2 1.7e-06 27.8 0.0 2.4 2 0 0 2 2 2 1 Retroviral aspartyl protease Retrotrans_gag PF03732.12 EIE90874.1 - 0.0002 21.3 2.3 0.0013 18.7 0.0 3.5 3 0 0 3 3 3 1 Retrotransposon gag protein gag-asp_proteas PF13975.1 EIE90874.1 - 0.00043 20.0 0.0 0.0011 18.7 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.5 EIE90874.1 - 0.006 16.1 0.6 0.014 14.9 0.1 1.8 2 0 0 2 2 2 1 Aspartyl protease PMC2NT PF08066.7 EIE90874.1 - 0.035 14.3 0.9 17 5.8 0.0 3.1 2 0 0 2 2 2 0 PMC2NT (NUC016) domain Peptidase_M3_N PF08439.5 EIE90874.1 - 0.052 13.5 1.7 0.13 12.3 0.2 2.4 2 0 0 2 2 2 0 Oligopeptidase F RVP_2 PF08284.6 EIE90874.1 - 0.068 13.0 0.1 0.25 11.2 0.0 1.9 2 0 0 2 2 2 0 Retroviral aspartyl protease DUF3479 PF11965.3 EIE90874.1 - 0.11 12.2 1.0 0.18 11.6 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3479) FlxA PF14282.1 EIE90874.1 - 0.34 10.8 5.0 3.2 7.7 3.5 2.6 1 1 0 1 1 1 0 FlxA-like protein IncA PF04156.9 EIE90874.1 - 2.9 7.4 4.5 7.6 6.0 3.1 1.7 1 0 0 1 1 1 0 IncA protein AAR2 PF05282.6 EIE90877.1 - 2.6e-15 56.2 0.1 1.2e-13 50.8 0.0 2.7 2 1 0 2 2 2 1 AAR2 protein Methyltransf_11 PF08241.7 EIE90877.1 - 5.6e-13 49.1 0.0 1.6e-12 47.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIE90877.1 - 1.5e-10 41.0 0.0 2.9e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIE90877.1 - 1.4e-08 34.4 0.0 3.2e-08 33.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIE90877.1 - 1.7e-07 30.6 0.0 4e-07 29.3 0.0 1.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EIE90877.1 - 1.1e-06 28.8 0.0 4.7e-06 26.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIE90877.1 - 5e-05 23.7 0.0 0.00017 21.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 EIE90877.1 - 6.1e-05 22.3 0.0 0.00012 21.3 0.0 1.5 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_4 PF02390.12 EIE90877.1 - 0.00014 20.9 0.1 0.00046 19.2 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase MetW PF07021.7 EIE90877.1 - 0.00058 19.2 0.0 0.001 18.4 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_8 PF05148.10 EIE90877.1 - 0.0015 18.2 0.0 0.0055 16.3 0.0 2.0 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_26 PF13659.1 EIE90877.1 - 0.0021 18.0 0.0 0.0043 17.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIE90877.1 - 0.0065 17.0 0.0 0.026 15.1 0.0 2.1 2 1 0 2 2 1 1 Methyltransferase domain TehB PF03848.9 EIE90877.1 - 0.029 13.5 0.0 0.069 12.3 0.0 1.6 1 0 0 1 1 1 0 Tellurite resistance protein TehB MTS PF05175.9 EIE90877.1 - 0.042 13.2 0.0 0.082 12.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain PCMT PF01135.14 EIE90877.1 - 0.17 11.4 0.2 0.56 9.7 0.0 1.8 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PH PF00169.24 EIE90878.1 - 2.5e-12 46.8 1.5 4.7e-12 46.0 1.0 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EIE90878.1 - 3.4e-06 27.2 1.7 6.8e-06 26.3 1.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 EIE90878.1 - 0.00097 19.1 0.9 0.065 13.3 0.0 2.3 2 0 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.1 EIE90878.1 - 0.0073 16.4 1.8 0.016 15.3 1.3 1.6 1 1 0 1 1 1 1 Pleckstrin homology domain Alk_phosphatase PF00245.15 EIE90879.1 - 3.4e-89 299.4 0.5 5.5e-47 160.4 0.0 2.1 1 1 1 2 2 2 2 Alkaline phosphatase Metalloenzyme PF01676.13 EIE90879.1 - 0.0017 17.7 2.4 0.0033 16.8 1.6 1.4 1 1 0 1 1 1 1 Metalloenzyme superfamily Cyclin PF08613.6 EIE90881.1 - 0.00084 19.7 1.8 0.0014 19.0 0.1 2.1 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 EIE90881.1 - 0.0038 16.7 0.2 0.15 11.6 0.1 2.5 2 1 0 2 2 2 1 Cyclin, N-terminal domain MFS_1 PF07690.11 EIE90882.1 - 3.7e-34 117.9 20.3 2.8e-32 111.8 9.5 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIE90882.1 - 5.4e-06 25.2 23.1 7.7e-06 24.7 4.8 3.1 2 1 1 3 3 3 3 Sugar (and other) transporter ESSS PF10183.4 EIE90882.1 - 0.0082 16.5 0.1 0.026 14.9 0.0 1.8 2 0 0 2 2 2 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF3099 PF11298.3 EIE90882.1 - 0.031 14.0 0.3 0.1 12.3 0.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3099) DUF4131 PF13567.1 EIE90882.1 - 0.84 9.0 5.1 5.3 6.4 0.0 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4131) PAS_3 PF08447.6 EIE90883.1 - 0.0041 17.1 0.0 0.01 15.8 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_11 PF14598.1 EIE90883.1 - 0.0047 16.8 1.0 0.02 14.8 0.1 2.3 1 1 1 2 2 2 1 PAS domain PAS PF00989.19 EIE90883.1 - 0.14 11.9 0.0 0.42 10.4 0.0 1.8 1 0 0 1 1 1 0 PAS fold WD40 PF00400.27 EIE90884.1 - 7.2e-15 54.2 0.1 0.00074 19.3 0.0 6.5 6 0 0 6 6 6 4 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EIE90884.1 - 0.00023 19.5 0.0 0.0029 15.9 0.0 2.3 2 0 0 2 2 2 1 Cytochrome D1 heme domain DUF3312 PF11768.3 EIE90884.1 - 0.0022 16.2 0.0 0.0052 15.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3312) Apc4_WD40 PF12894.2 EIE90884.1 - 0.041 13.3 0.0 0.55 9.7 0.0 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain SNF2_N PF00176.18 EIE90886.1 - 8.9e-40 136.3 0.1 1.7e-39 135.4 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain ASXH PF13919.1 EIE90887.1 - 2.9e-11 43.2 1.3 4.6e-11 42.6 0.9 1.3 1 0 0 1 1 1 1 Asx homology domain DUF4426 PF14467.1 EIE90889.1 - 0.0042 16.8 4.2 0.053 13.3 0.1 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4426) KLRAQ PF10205.4 EIE90889.1 - 1.1 9.2 15.7 0.28 11.2 7.1 2.6 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein DivIVA PF05103.8 EIE90889.1 - 1.4 8.9 26.1 0.27 11.2 10.8 3.2 3 1 0 3 3 3 0 DivIVA protein DUF3708 PF12501.3 EIE90889.1 - 4.1 7.2 9.4 3.4 7.4 2.8 2.4 1 1 1 2 2 2 0 Phosphate ATP-binding cassette transporter Endonuclease_NS PF01223.18 EIE90890.1 - 2.1e-62 210.4 0.2 2.7e-62 210.0 0.1 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease DUF533 PF04391.7 EIE90890.1 - 0.12 11.7 0.1 0.17 11.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF533) KH_3 PF13014.1 EIE90891.1 - 0.00081 18.9 0.0 0.0019 17.7 0.0 1.6 1 0 0 1 1 1 1 KH domain KH_1 PF00013.24 EIE90891.1 - 0.00087 18.8 0.0 0.0022 17.6 0.0 1.7 1 0 0 1 1 1 1 KH domain KH_4 PF13083.1 EIE90891.1 - 0.028 14.0 0.0 0.06 12.9 0.0 1.5 1 0 0 1 1 1 0 KH domain PITH PF06201.8 EIE90892.1 - 1.4e-47 161.2 0.0 2.1e-47 160.6 0.0 1.3 1 0 0 1 1 1 1 PITH domain BCIP PF13862.1 EIE90893.1 - 1.5e-51 174.6 10.9 6.6e-50 169.3 7.6 2.2 1 1 0 1 1 1 1 p21-C-terminal region-binding protein Pectate_lyase_2 PF06917.7 EIE90893.1 - 0.01 14.1 0.1 0.013 13.7 0.1 1.1 1 0 0 1 1 1 0 Periplasmic pectate lyase HsdM_N PF12161.3 EIE90893.1 - 0.21 12.0 5.0 0.21 12.0 0.2 2.3 2 0 0 2 2 2 0 HsdM N-terminal domain Tetraspannin PF00335.15 EIE90895.1 - 1.1 8.4 8.0 3.6 6.7 5.6 1.8 1 1 0 1 1 1 0 Tetraspanin family Hex_IIIa PF02455.11 EIE90896.1 - 2.3 6.8 5.8 2.9 6.4 4.0 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) SDF PF00375.13 EIE90897.1 - 9.3e-71 238.6 28.0 1.1e-70 238.4 19.4 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family DUF2461 PF09365.5 EIE90898.1 - 2.2e-59 200.3 0.1 3e-59 199.9 0.1 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) DUF2478 PF10649.4 EIE90898.1 - 0.014 14.7 0.1 0.026 13.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2478) SSXRD PF09514.5 EIE90898.1 - 0.063 12.6 2.1 0.14 11.4 1.5 1.6 1 0 0 1 1 1 0 SSXRD motif GAS PF13851.1 EIE90899.1 - 8.4e-05 21.8 29.2 0.004 16.3 5.9 2.3 2 0 0 2 2 2 2 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.4 EIE90899.1 - 0.0047 16.7 12.0 0.0047 16.7 8.3 2.5 2 1 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CS PF04969.11 EIE90900.1 - 5.1e-06 26.9 2.6 8.1e-06 26.3 1.2 1.7 2 0 0 2 2 2 1 CS domain DWNN PF08783.6 EIE90900.1 - 0.013 15.3 1.0 0.018 14.9 0.4 1.6 2 0 0 2 2 2 0 DWNN domain Asn_synthase PF00733.16 EIE90902.1 - 5.3e-71 239.1 0.1 7.5e-71 238.6 0.1 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EIE90902.1 - 5e-38 129.6 0.0 9.3e-38 128.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EIE90902.1 - 4.1e-31 107.6 0.0 1.1e-30 106.2 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.3 EIE90902.1 - 6.9e-11 41.7 0.0 1.3e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein GATase_2 PF00310.16 EIE90902.1 - 1.5e-07 30.5 0.0 0.25 10.0 0.0 3.2 1 1 2 3 3 3 3 Glutamine amidotransferases class-II NAD_synthase PF02540.12 EIE90902.1 - 0.0045 15.9 0.0 0.0096 14.8 0.0 1.4 1 0 0 1 1 1 1 NAD synthase QueC PF06508.8 EIE90902.1 - 0.13 11.5 0.0 0.25 10.5 0.0 1.4 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC Complex1_LYR_1 PF13232.1 EIE90903.1 - 1.3e-19 70.1 1.6 1.8e-19 69.7 1.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EIE90903.1 - 3.5e-19 68.3 1.6 5.8e-19 67.6 0.8 1.5 1 1 1 2 2 2 1 Complex 1 protein (LYR family) Methyltransf_11 PF08241.7 EIE90904.1 - 3.5e-14 53.0 0.0 7.3e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIE90904.1 - 9.3e-12 44.9 0.0 1.2e-11 44.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIE90904.1 - 1.4e-07 31.2 0.0 4.8e-07 29.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 EIE90904.1 - 4.9e-07 29.1 0.0 6.1e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EIE90904.1 - 7.6e-06 26.4 0.0 5.4e-05 23.7 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_8 PF05148.10 EIE90904.1 - 0.00014 21.6 0.0 0.00021 21.0 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_12 PF08242.7 EIE90904.1 - 0.00019 21.8 0.0 0.00089 19.6 0.0 2.2 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIE90904.1 - 0.00022 21.5 0.0 0.00046 20.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIE90904.1 - 0.00064 18.9 0.0 0.0069 15.5 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family GidB PF02527.10 EIE90904.1 - 0.0037 16.4 0.0 0.025 13.7 0.0 2.2 2 0 0 2 2 2 1 rRNA small subunit methyltransferase G UPF0258 PF06789.7 EIE90904.1 - 0.039 14.0 0.1 0.076 13.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0258) Methyltransf_4 PF02390.12 EIE90904.1 - 0.051 12.6 0.0 1.3 8.0 0.0 2.2 2 0 0 2 2 2 0 Putative methyltransferase MTS PF05175.9 EIE90904.1 - 0.091 12.1 0.0 1.8 7.9 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_16 PF10294.4 EIE90904.1 - 0.096 12.1 0.1 0.39 10.1 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase Glyco_trans_1_4 PF13692.1 EIE90905.1 - 4.2e-18 65.8 0.0 1e-17 64.5 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 EIE90905.1 - 1.5e-06 27.7 0.0 2.3e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EIE90905.1 - 0.00095 19.3 0.0 0.002 18.2 0.0 1.5 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Pkinase PF00069.20 EIE90906.1 - 6.3e-55 186.1 0.0 8.6e-55 185.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE90906.1 - 2e-35 122.1 0.0 2.5e-35 121.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE90906.1 - 8.8e-05 21.6 0.0 0.0002 20.4 0.0 1.6 2 0 0 2 2 2 1 Kinase-like RNA_pol_I_A49 PF06870.7 EIE90907.1 - 1.7e-77 260.6 2.9 1.9e-77 260.4 2.0 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor Methyltransf_31 PF13847.1 EIE90908.1 - 2.6e-13 49.8 0.1 6.3e-13 48.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EIE90908.1 - 3.3e-11 42.8 0.0 4.6e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 EIE90908.1 - 3.1e-10 40.6 0.0 1e-09 38.9 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIE90908.1 - 8e-10 39.0 0.0 3.3e-09 37.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIE90908.1 - 2e-09 37.4 0.0 3.4e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 EIE90908.1 - 1.4e-08 34.0 0.0 1.8e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_23 PF13489.1 EIE90908.1 - 9.5e-08 31.9 0.0 1.7e-07 31.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EIE90908.1 - 6.4e-07 28.9 0.3 1.5e-06 27.7 0.1 1.5 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_9 PF08003.6 EIE90908.1 - 6.8e-07 28.2 0.1 9.6e-07 27.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_12 PF08242.7 EIE90908.1 - 6.3e-06 26.5 0.0 1.3e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIE90908.1 - 2.2e-05 24.7 0.1 5.8e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 EIE90908.1 - 4.7e-05 22.5 0.0 6.5e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.14 EIE90908.1 - 0.00015 21.7 0.0 0.00035 20.6 0.0 1.5 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_24 PF13578.1 EIE90908.1 - 0.0044 17.8 0.0 0.01 16.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 EIE90908.1 - 0.0072 15.9 0.1 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_32 PF13679.1 EIE90908.1 - 0.011 15.3 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.4 EIE90908.1 - 0.012 15.1 0.2 0.017 14.5 0.1 1.2 1 0 0 1 1 1 0 Putative methyltransferase TehB PF03848.9 EIE90908.1 - 0.02 14.0 1.4 0.069 12.3 1.0 1.9 1 1 0 1 1 1 0 Tellurite resistance protein TehB PCMT PF01135.14 EIE90908.1 - 0.06 12.8 0.1 0.14 11.7 0.1 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Myc_N PF01056.13 EIE90909.1 - 0.4 9.7 2.6 0.5 9.4 1.8 1.1 1 0 0 1 1 1 0 Myc amino-terminal region ABC_tran PF00005.22 EIE90910.1 - 1.3e-46 158.3 0.0 2.9e-29 102.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EIE90910.1 - 3.9e-44 151.1 34.7 1.6e-24 86.7 10.1 3.6 3 0 0 3 3 3 2 ABC transporter transmembrane region AAA_25 PF13481.1 EIE90910.1 - 2.1e-07 30.5 0.1 0.0019 17.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain ResIII PF04851.10 EIE90910.1 - 1.6e-06 28.1 0.2 0.014 15.2 0.0 3.1 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit T2SE PF00437.15 EIE90910.1 - 1.7e-06 27.1 0.0 0.038 12.9 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_23 PF13476.1 EIE90910.1 - 2.9e-05 24.4 0.9 0.01 16.1 0.0 3.0 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 EIE90910.1 - 6e-05 22.3 6.7 0.0081 15.4 1.7 3.7 2 2 0 2 2 2 1 RecF/RecN/SMC N terminal domain FtsK_SpoIIIE PF01580.13 EIE90910.1 - 9.4e-05 21.9 0.1 0.056 12.9 0.0 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_29 PF13555.1 EIE90910.1 - 0.00015 21.2 1.5 0.1 12.1 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 EIE90910.1 - 0.00052 20.0 2.0 0.036 14.0 0.0 4.0 3 1 0 3 3 3 1 AAA domain AAA_10 PF12846.2 EIE90910.1 - 0.00086 18.8 0.1 0.26 10.6 0.0 2.4 2 0 0 2 2 2 1 AAA-like domain DUF87 PF01935.12 EIE90910.1 - 0.0012 18.7 4.3 0.14 11.9 0.1 2.4 2 0 0 2 2 2 2 Domain of unknown function DUF87 AAA_16 PF13191.1 EIE90910.1 - 0.0031 17.5 0.6 0.95 9.4 0.1 2.7 2 1 0 2 2 2 1 AAA ATPase domain KaiC PF06745.8 EIE90910.1 - 0.0096 15.0 0.2 1.7 7.7 0.0 2.4 2 0 0 2 2 2 1 KaiC AAA_22 PF13401.1 EIE90910.1 - 0.01 15.9 0.4 9.6 6.3 0.0 3.2 3 0 0 3 3 3 0 AAA domain TrwB_AAD_bind PF10412.4 EIE90910.1 - 0.013 14.1 0.6 1.6 7.2 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain DUF2075 PF09848.4 EIE90910.1 - 0.014 14.3 0.4 0.29 10.0 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.1 EIE90910.1 - 0.031 14.5 0.2 4.5 7.5 0.1 3.1 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 EIE90910.1 - 0.072 12.5 0.0 13 5.1 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein PhoH PF02562.11 EIE90910.1 - 0.1 11.7 0.3 6.9 5.8 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein Zeta_toxin PF06414.7 EIE90910.1 - 0.14 11.2 0.3 16 4.4 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin NACHT PF05729.7 EIE90910.1 - 0.21 11.2 2.3 9.9 5.7 0.2 2.5 2 0 0 2 2 2 0 NACHT domain MobB PF03205.9 EIE90910.1 - 0.34 10.6 2.5 3.4 7.3 0.1 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 EIE90910.1 - 1.6 9.5 7.3 1.2 10.0 0.8 3.1 3 0 0 3 3 2 0 AAA domain Voltage_CLC PF00654.15 EIE90911.1 - 1.3e-75 254.6 35.1 1.7e-43 149.0 10.8 3.3 2 2 1 3 3 3 2 Voltage gated chloride channel SUR7 PF06687.7 EIE90911.1 - 0.00045 19.8 0.1 0.00045 19.8 0.1 2.5 3 0 0 3 3 3 1 SUR7/PalI family CBS PF00571.23 EIE90911.1 - 0.01 15.5 0.1 0.045 13.5 0.0 2.1 2 0 0 2 2 2 0 CBS domain DUF3300 PF11737.3 EIE90911.1 - 0.017 14.4 0.2 0.31 10.2 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3300) TAT_signal PF10518.4 EIE90911.1 - 0.078 13.0 0.4 0.078 13.0 0.3 2.7 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence MFS_1 PF07690.11 EIE90912.1 - 2.4e-30 105.4 36.8 2.4e-30 105.4 25.5 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.15 EIE90912.1 - 7.5e-06 24.2 0.2 1.5e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family DDE_3 PF13358.1 EIE90917.1 - 8.6e-07 28.8 0.1 1.5e-06 28.0 0.1 1.4 2 0 0 2 2 2 1 DDE superfamily endonuclease Sugar_tr PF00083.19 EIE90918.1 - 1.4e-121 406.2 18.9 1.8e-121 405.9 13.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIE90918.1 - 4.5e-24 84.8 45.8 2.8e-22 78.9 13.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF441 PF04284.8 EIE90918.1 - 0.0012 18.6 0.2 0.0034 17.2 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF441) TM1586_NiRdase PF14512.1 EIE90919.1 - 0.063 12.4 0.0 0.072 12.2 0.0 1.1 1 0 0 1 1 1 0 Putative TM nitroreductase Hira PF07569.6 EIE90920.1 - 4.3e-46 156.8 2.2 2.8e-45 154.2 1.5 2.0 1 1 0 1 1 1 1 TUP1-like enhancer of split Invas_SpaK PF03519.9 EIE90920.1 - 0.019 14.8 0.2 0.038 13.8 0.1 1.5 1 0 0 1 1 1 0 Invasion protein B family LRR_4 PF12799.2 EIE90921.1 - 2.4e-18 65.3 7.0 1.1e-08 34.5 1.1 2.7 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EIE90921.1 - 5.6e-17 61.2 9.7 3.2e-11 42.8 4.5 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 EIE90921.1 - 5.7e-14 50.0 9.0 0.045 13.7 0.0 5.6 5 0 0 5 5 5 4 Leucine Rich Repeat PRKCSH PF07915.8 EIE90921.1 - 8.6e-09 36.0 5.5 8.6e-09 36.0 3.8 2.5 3 0 0 3 3 3 1 Glucosidase II beta subunit-like protein LRR_7 PF13504.1 EIE90921.1 - 9.7e-09 34.0 8.0 1.6 9.2 0.1 5.2 4 0 0 4 4 4 4 Leucine rich repeat LRR_6 PF13516.1 EIE90921.1 - 0.00016 21.4 7.2 4.9 7.5 0.1 5.0 4 0 0 4 4 4 2 Leucine Rich repeat DUF2397 PF09660.5 EIE90921.1 - 0.058 11.9 4.0 0.096 11.2 2.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2397) TAF4 PF05236.9 EIE90922.1 - 3e-20 72.6 10.1 4.3e-19 68.8 0.0 3.3 2 2 1 3 3 3 2 Transcription initiation factor TFIID component TAF4 family EF-hand_like PF09279.6 EIE90923.1 - 0.0023 17.9 9.8 0.0057 16.6 2.5 2.9 3 0 0 3 3 3 1 Phosphoinositide-specific phospholipase C, efhand-like UIM PF02809.15 EIE90923.1 - 0.0043 16.5 0.1 0.0043 16.5 0.1 2.5 2 0 0 2 2 2 1 Ubiquitin interaction motif zf-C2H2_jaz PF12171.3 EIE90923.1 - 0.094 12.8 0.1 0.26 11.5 0.1 1.8 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EIE90923.1 - 0.13 12.4 0.0 0.34 11.1 0.0 1.7 1 0 0 1 1 1 0 Zinc-finger of C2H2 type GATA PF00320.22 EIE90924.1 - 3.3e-31 106.3 15.3 3.1e-16 58.3 2.8 2.4 2 0 0 2 2 2 2 GATA zinc finger Zn-ribbon_8 PF09723.5 EIE90924.1 - 0.00095 19.0 1.5 0.36 10.8 0.1 2.4 2 0 0 2 2 2 2 Zinc ribbon domain TF_Zn_Ribbon PF08271.7 EIE90924.1 - 0.0012 18.1 5.0 0.24 10.7 0.3 2.6 2 0 0 2 2 2 2 TFIIB zinc-binding DZR PF12773.2 EIE90924.1 - 0.014 15.1 8.2 2.9 7.7 6.4 3.0 1 1 1 2 2 2 0 Double zinc ribbon zf-CHY PF05495.7 EIE90924.1 - 0.024 14.8 2.7 3.9 7.7 1.4 2.5 1 1 1 2 2 2 0 CHY zinc finger Zn_Tnp_IS1595 PF12760.2 EIE90924.1 - 0.03 14.1 3.0 0.42 10.4 0.2 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-ribbon_3 PF13248.1 EIE90924.1 - 0.036 13.2 7.8 0.52 9.5 0.1 2.9 2 1 0 2 2 2 0 zinc-ribbon domain zf-B_box PF00643.19 EIE90924.1 - 0.058 13.2 6.5 23 4.9 0.0 4.0 4 0 0 4 4 4 0 B-box zinc finger DUF2318 PF10080.4 EIE90924.1 - 0.088 12.5 0.6 5.7 6.7 0.0 2.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) eIF-5_eIF-2B PF01873.12 EIE90924.1 - 0.11 12.1 4.0 3.9 7.1 0.2 2.4 2 0 0 2 2 2 0 Domain found in IF2B/IF5 RRN7 PF11781.3 EIE90924.1 - 0.18 11.2 6.0 3.1 7.3 0.2 2.9 2 1 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 FYVE PF01363.16 EIE90924.1 - 0.49 10.3 4.9 2.1 8.2 3.3 2.1 1 1 0 1 1 1 0 FYVE zinc finger OrfB_Zn_ribbon PF07282.6 EIE90924.1 - 1.2 8.8 6.4 2.7 7.7 0.2 2.9 3 1 1 4 4 4 0 Putative transposase DNA-binding domain Sec1 PF00995.18 EIE90925.1 - 6.6e-112 374.9 0.0 8.3e-112 374.6 0.0 1.0 1 0 0 1 1 1 1 Sec1 family TnpV PF14198.1 EIE90926.1 - 0.78 9.6 6.3 0.24 11.3 2.3 1.6 2 0 0 2 2 2 0 Transposon-encoded protein TnpV GldM_N PF12081.3 EIE90926.1 - 1.4 8.4 7.2 0.35 10.3 2.4 1.7 2 0 0 2 2 2 0 GldM N-terminal domain DUF1115 PF06544.7 EIE90926.1 - 1.7 8.3 10.4 16 5.2 7.2 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1115) Ribosomal_L37e PF01907.14 EIE90927.1 - 1e-24 86.0 12.6 1.8e-24 85.2 8.7 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.2 EIE90927.1 - 0.0025 17.6 2.8 0.0046 16.7 2.0 1.4 1 0 0 1 1 1 1 Double zinc ribbon SelR PF01641.13 EIE90927.1 - 0.032 13.9 0.3 0.079 12.6 0.2 1.7 1 0 0 1 1 1 0 SelR domain MFS_1 PF07690.11 EIE90927.1 - 0.093 11.4 19.4 0.029 13.0 10.3 2.2 2 1 1 3 3 3 0 Major Facilitator Superfamily HypA PF01155.14 EIE90927.1 - 0.11 12.1 0.2 0.18 11.4 0.1 1.3 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-RING_5 PF14634.1 EIE90927.1 - 0.21 11.3 4.0 0.42 10.3 2.8 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-HYPF PF07503.7 EIE90927.1 - 3.2 7.2 6.4 14 5.1 2.1 2.6 2 1 0 2 2 2 0 HypF finger G-alpha PF00503.15 EIE90928.1 - 1.6e-98 329.9 3.0 1.8e-98 329.7 2.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EIE90928.1 - 1.2e-10 40.8 0.6 2.4e-10 39.9 0.1 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family Rhodanese PF00581.15 EIE90929.1 - 2.4e-17 63.3 0.0 3.2e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain Actin PF00022.14 EIE90930.1 - 1e-36 126.2 0.0 1.8e-36 125.4 0.0 1.4 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EIE90930.1 - 2e-05 23.3 0.0 0.0026 16.3 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein DUF1395 PF07160.7 EIE90930.1 - 0.061 12.8 0.2 0.061 12.8 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1395) PA26 PF04636.8 EIE90930.1 - 0.33 9.6 2.4 0.58 8.7 1.7 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF1749 PF08538.5 EIE90931.1 - 9e-34 116.7 0.2 1.1e-33 116.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) DUF900 PF05990.7 EIE90931.1 - 0.034 13.4 0.0 0.047 13.0 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF420 PF04238.7 EIE90932.1 - 0.065 13.1 14.4 0.085 12.8 0.9 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF420) Transmemb_17 PF09799.4 EIE90932.1 - 9.7 6.5 14.9 0.7 10.2 5.4 2.6 2 1 1 3 3 3 0 Predicted membrane protein ABC2_membrane PF01061.19 EIE90933.1 - 3.1e-70 235.5 74.0 2.9e-44 150.7 16.7 4.5 4 1 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.22 EIE90933.1 - 7.5e-38 129.9 0.0 2.6e-20 73.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EIE90933.1 - 3.2e-26 91.0 0.5 3e-19 68.5 0.0 3.3 4 0 0 4 4 2 2 CDR ABC transporter ABC_trans_N PF14510.1 EIE90933.1 - 6e-10 39.0 0.0 1.4e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal ABC2_membrane_3 PF12698.2 EIE90933.1 - 5.4e-09 35.5 8.4 5.4e-09 35.5 5.8 3.2 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 EIE90933.1 - 7.4e-06 26.1 0.0 0.16 11.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EIE90933.1 - 3e-05 23.5 0.0 0.0046 16.3 0.0 2.6 3 0 0 3 3 2 1 AAA domain DUF258 PF03193.11 EIE90933.1 - 5e-05 22.5 0.1 0.0021 17.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EIE90933.1 - 0.00026 21.1 0.4 0.098 12.7 0.0 3.1 3 1 0 3 3 2 1 AAA domain AAA_29 PF13555.1 EIE90933.1 - 0.00056 19.3 0.2 0.0075 15.7 0.1 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain UPF0079 PF02367.12 EIE90933.1 - 0.0013 18.3 1.2 0.95 9.1 0.1 2.4 2 0 0 2 2 2 2 Uncharacterised P-loop hydrolase UPF0079 AAA_33 PF13671.1 EIE90933.1 - 0.0033 17.2 0.9 0.46 10.3 0.0 2.8 3 0 0 3 3 2 1 AAA domain cobW PF02492.14 EIE90933.1 - 0.0071 15.8 0.1 0.11 11.9 0.0 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.1 EIE90933.1 - 0.014 15.1 0.4 2.2 8.0 0.1 2.6 2 0 0 2 2 2 0 Part of AAA domain AAA_16 PF13191.1 EIE90933.1 - 0.015 15.2 0.1 0.38 10.7 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.7 EIE90933.1 - 0.021 13.8 0.0 0.34 9.9 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin SbcCD_C PF13558.1 EIE90933.1 - 0.032 14.1 0.5 0.24 11.3 0.0 2.6 3 0 0 3 3 2 0 Putative exonuclease SbcCD, C subunit Arch_ATPase PF01637.13 EIE90933.1 - 0.037 13.7 0.0 1.8 8.1 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase AAA_17 PF13207.1 EIE90933.1 - 0.041 14.7 0.0 0.67 10.7 0.0 2.8 3 0 0 3 3 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EIE90933.1 - 0.045 13.2 0.7 3.2 7.1 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_18 PF13238.1 EIE90933.1 - 0.076 13.3 0.0 0.62 10.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 EIE90933.1 - 0.088 12.7 0.3 0.25 11.2 0.1 1.9 2 0 0 2 2 1 0 AAA domain NACHT PF05729.7 EIE90933.1 - 0.12 11.9 0.4 2.8 7.5 0.1 2.4 2 0 0 2 2 2 0 NACHT domain AAA_15 PF13175.1 EIE90933.1 - 0.16 10.9 0.0 3.3 6.6 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain PduV-EutP PF10662.4 EIE90933.1 - 0.19 11.2 0.2 1.3 8.5 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.1 EIE90933.1 - 0.23 11.0 0.6 4.9 6.6 0.1 2.3 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EIE90933.1 - 0.32 9.8 0.4 14 4.3 0.1 2.3 2 0 0 2 2 2 0 NB-ARC domain SCA7 PF08313.7 EIE90934.1 - 1.1e-19 69.7 0.4 2.2e-19 68.8 0.3 1.5 1 0 0 1 1 1 1 SCA7, zinc-binding domain DIT1_PvcA PF05141.7 EIE90934.1 - 0.056 12.7 0.0 0.081 12.2 0.0 1.3 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein Ank_2 PF12796.2 EIE90935.1 - 4.9e-45 151.7 1.5 8.6e-21 74.0 0.2 4.3 1 1 4 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 EIE90935.1 - 3.6e-25 86.4 0.2 3.3e-08 32.9 0.0 7.1 8 0 0 8 8 8 4 Ankyrin repeat Ank_4 PF13637.1 EIE90935.1 - 4.2e-24 84.4 0.4 1.4e-09 38.2 0.0 3.7 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EIE90935.1 - 1e-20 73.2 0.5 6.2e-09 35.8 0.0 4.7 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIE90935.1 - 8.9e-17 59.5 0.1 3.3e-05 23.7 0.0 5.1 5 0 0 5 5 5 3 Ankyrin repeat E2F_TDP PF02319.15 EIE90936.1 - 1.2e-13 50.4 3.9 1.6e-13 49.9 0.4 2.1 2 0 0 2 2 2 1 E2F/DP family winged-helix DNA-binding domain DP PF08781.5 EIE90936.1 - 0.0031 17.2 2.9 0.0035 17.0 1.3 1.7 2 0 0 2 2 2 1 Transcription factor DP YebO PF13974.1 EIE90936.1 - 0.22 11.3 1.7 0.24 11.2 0.2 1.8 2 0 0 2 2 2 0 YebO-like protein Mg_trans_NIPA PF05653.9 EIE90938.1 - 2.9e-25 88.8 14.4 4.3e-25 88.2 10.0 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.15 EIE90938.1 - 0.0026 17.7 2.5 0.0026 17.7 1.7 2.9 2 1 1 3 3 3 1 EamA-like transporter family EmrE PF13536.1 EIE90938.1 - 0.0088 16.2 3.4 0.0088 16.2 2.4 2.7 2 1 0 2 2 2 1 Multidrug resistance efflux transporter Neurensin PF14927.1 EIE90938.1 - 0.098 12.0 0.9 2.2 7.6 0.0 2.4 2 0 0 2 2 2 0 Neurensin NIF PF03031.13 EIE90939.1 - 2.1e-05 24.2 0.1 5.4e-05 22.9 0.1 1.7 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Pkinase PF00069.20 EIE90940.1 - 9.4e-60 201.9 0.0 1.1e-59 201.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE90940.1 - 7.3e-19 67.8 0.0 1.3e-18 66.9 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE90940.1 - 6.3e-05 22.0 0.0 0.0013 17.7 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Choline_kinase PF01633.15 EIE90940.1 - 0.0096 15.5 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 EIE90940.1 - 0.015 15.0 0.0 0.052 13.2 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family GDA1_CD39 PF01150.12 EIE90941.1 - 1.1e-100 337.2 0.0 1.3e-100 336.9 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.11 EIE90941.1 - 0.0063 15.7 0.0 0.0088 15.2 0.0 1.2 1 0 0 1 1 1 1 Ppx/GppA phosphatase family Prenyltransf PF01255.14 EIE90942.1 - 9.7e-70 234.1 0.1 1.2e-69 233.8 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase SNF2_N PF00176.18 EIE90943.1 - 1.4e-58 198.0 0.0 2e-58 197.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EIE90943.1 - 3.4e-16 58.8 0.0 2.6e-15 56.0 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.1 EIE90943.1 - 1.1e-10 40.9 7.2 2.7e-10 39.7 5.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIE90943.1 - 7.1e-09 35.1 8.4 1.6e-08 34.0 5.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIE90943.1 - 9.3e-09 35.1 7.9 9.3e-09 35.1 5.4 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EIE90943.1 - 2.7e-08 33.5 7.3 6.6e-08 32.2 5.0 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 EIE90943.1 - 2.1e-07 30.6 7.5 5.4e-07 29.3 5.2 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 EIE90943.1 - 2.4e-05 23.9 2.9 6.8e-05 22.5 2.0 1.8 1 0 0 1 1 1 1 RING-type zinc-finger DEAD PF00270.24 EIE90943.1 - 4.8e-05 22.9 0.0 0.00012 21.6 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_5 PF14634.1 EIE90943.1 - 0.00013 21.6 7.0 0.0003 20.4 4.8 1.7 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.1 EIE90943.1 - 0.00017 21.0 3.3 0.00051 19.5 2.3 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-UDP PF14569.1 EIE90943.1 - 0.007 16.0 1.5 0.021 14.5 1.0 1.8 1 0 0 1 1 1 1 Zinc-binding RING-finger zf-RING_4 PF14570.1 EIE90943.1 - 0.0074 15.8 8.5 0.017 14.7 5.9 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Baculo_IE-1 PF05290.6 EIE90943.1 - 0.011 15.4 0.2 0.023 14.4 0.2 1.5 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) MAPEG PF01124.13 EIE90944.1 - 1.4e-06 27.9 2.4 2.4e-06 27.1 1.7 1.4 1 1 0 1 1 1 1 MAPEG family MIG-14_Wnt-bd PF06664.7 EIE90944.1 - 0.018 13.8 2.5 0.028 13.2 1.7 1.3 1 0 0 1 1 1 0 Wnt-binding factor required for Wnt secretion Exo_endo_phos PF03372.18 EIE90945.1 - 0.00096 19.1 0.0 0.0013 18.7 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Podoplanin PF05808.6 EIE90946.1 - 0.0019 17.8 13.5 0.0029 17.2 9.4 1.2 1 0 0 1 1 1 1 Podoplanin Plasmodium_Vir PF05795.6 EIE90946.1 - 1.7 7.7 11.4 7.5 5.6 7.9 2.1 1 1 0 1 1 1 0 Plasmodium vivax Vir protein Dicty_REP PF05086.7 EIE90946.1 - 8.1 4.0 14.7 11 3.6 10.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Prp19_bind PF06991.6 EIE90947.1 - 1.8e-77 260.3 38.8 1.8e-77 260.3 26.9 2.2 1 1 1 2 2 2 1 Splicing factor, Prp19-binding domain MIP PF00230.15 EIE90948.1 - 7.3e-50 169.5 9.4 9.3e-50 169.1 6.5 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF3925 PF13063.1 EIE90948.1 - 0.059 13.3 2.5 0.18 11.8 1.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3925) Fungal_trans PF04082.13 EIE90949.1 - 4.1e-06 25.8 4.1 1.1e-05 24.4 2.8 1.9 1 0 0 1 1 1 1 Fungal specific transcription factor domain Di19_C PF14571.1 EIE90950.1 - 0.064 13.5 0.3 0.16 12.3 0.2 1.7 1 1 0 1 1 1 0 Stress-induced protein Di19, C-terminal HTH_Tnp_Tc3_2 PF01498.13 EIE90953.1 - 6.9e-08 32.4 1.1 1.5e-07 31.3 0.8 1.7 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.1 EIE90953.1 - 0.0019 17.9 0.0 0.0043 16.7 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_4 PF13613.1 EIE90953.1 - 0.054 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE90954.1 - 2.9e-07 30.4 1.1 5.7e-07 29.4 0.2 2.0 2 1 0 2 2 2 1 Transposase HTH_Tnp_Tc3_2 PF01498.13 EIE90955.1 - 0.0014 18.6 2.4 0.0017 18.3 0.9 1.9 2 1 0 2 2 2 1 Transposase PPDFL PF15060.1 EIE90955.1 - 0.066 13.2 0.0 0.094 12.7 0.0 1.2 1 0 0 1 1 1 0 Differentiation and proliferation regulator Leader_Erm PF08253.6 EIE90956.1 - 0.33 10.4 0.3 0.33 10.4 0.2 2.1 2 0 0 2 2 2 0 Erm Leader peptide Asp_protease_2 PF13650.1 EIE90959.1 - 1e-07 32.3 0.0 2.3e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EIE90959.1 - 0.00073 19.3 0.0 0.0036 17.0 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 EIE90959.1 - 0.04 13.8 0.0 0.18 11.7 0.0 2.1 2 1 0 2 2 2 0 Retroviral aspartyl protease DUF1789 PF08748.6 EIE90959.1 - 0.077 13.0 0.2 0.12 12.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1789) RVP_2 PF08284.6 EIE90959.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease rve PF00665.21 EIE90960.1 - 5.5e-24 84.5 0.0 2.2e-23 82.6 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 EIE90960.1 - 1e-13 51.1 0.1 3.6e-13 49.3 0.0 2.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE90960.1 - 1.1e-08 34.6 0.9 1.2e-07 31.2 0.1 2.9 3 0 0 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.12 EIE90960.1 - 2.3e-06 27.5 0.2 2.3e-06 27.5 0.1 3.0 2 0 0 2 2 2 1 Retrotransposon gag protein rve_3 PF13683.1 EIE90960.1 - 0.0058 16.1 0.0 0.025 14.1 0.0 2.2 1 0 0 1 1 1 1 Integrase core domain DDE_3 PF13358.1 EIE90961.1 - 5.4e-13 48.9 0.0 7.9e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease FlpD PF02662.11 EIE90961.1 - 0.15 11.7 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 Methyl-viologen-reducing hydrogenase, delta subunit Retrotrans_gag PF03732.12 EIE90962.1 - 7.4e-09 35.5 1.4 9.2e-09 35.2 0.3 1.7 2 0 0 2 2 2 1 Retrotransposon gag protein Autophagy_N PF03986.8 EIE90962.1 - 0.026 14.2 0.3 0.038 13.7 0.2 1.3 1 0 0 1 1 1 0 Autophagocytosis associated protein (Atg3), N-terminal domain RVT_1 PF00078.22 EIE90963.1 - 2.4e-27 95.7 0.0 7e-27 94.1 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EIE90963.1 - 2e-14 53.2 0.0 5.6e-14 51.7 0.0 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EIE90963.1 - 2.1e-05 24.6 0.4 6.6e-05 22.9 0.1 2.1 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family DDE_3 PF13358.1 EIE90964.1 - 9e-21 74.1 0.0 1.8e-20 73.1 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE90964.1 - 1.1e-15 57.4 1.9 2.8e-15 56.1 0.3 2.3 3 0 0 3 3 2 1 Transposase HTH_29 PF13551.1 EIE90964.1 - 2.7e-06 27.4 0.2 8.6e-06 25.8 0.2 1.9 2 0 0 2 2 1 1 Winged helix-turn helix HTH_38 PF13936.1 EIE90964.1 - 1.2e-05 24.7 0.1 3.3e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.1 EIE90964.1 - 7.6e-05 22.2 0.1 0.0028 17.2 0.0 2.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.1 EIE90964.1 - 9.7e-05 23.0 2.9 0.02 15.6 0.1 3.7 4 0 0 4 4 3 1 Homeodomain-like domain Sigma70_r4_2 PF08281.7 EIE90964.1 - 0.00054 19.3 0.6 0.024 14.0 0.0 3.2 4 0 0 4 4 4 1 Sigma-70, region 4 HTH_28 PF13518.1 EIE90964.1 - 0.0013 18.7 0.0 0.0056 16.6 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_21 PF13276.1 EIE90964.1 - 0.0014 18.6 0.1 0.13 12.2 0.0 2.8 3 0 0 3 3 3 1 HTH-like domain HTH_7 PF02796.10 EIE90964.1 - 0.0022 17.7 1.1 0.1 12.4 0.0 2.8 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase rve PF00665.21 EIE90964.1 - 0.0047 17.0 0.0 0.015 15.4 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain LacI PF00356.16 EIE90964.1 - 0.018 14.6 1.7 2.8 7.6 0.2 2.7 3 0 0 3 3 3 0 Bacterial regulatory proteins, lacI family HTH_Tnp_4 PF13613.1 EIE90964.1 - 0.022 14.2 0.1 0.057 12.9 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease CPSase_L_D3 PF02787.14 EIE90964.1 - 0.058 13.1 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain HTH_36 PF13730.1 EIE90964.1 - 0.074 13.1 0.4 4.1 7.6 0.0 2.9 3 0 0 3 3 2 0 Helix-turn-helix domain Sigma70_r4 PF04545.11 EIE90964.1 - 0.1 11.9 0.2 0.79 9.0 0.0 2.6 4 0 0 4 4 4 0 Sigma-70, region 4 HTH_Tnp_ISL3 PF13542.1 EIE90964.1 - 0.15 11.2 2.5 8.4 5.6 0.0 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 HTH_17 PF12728.2 EIE90964.1 - 0.2 11.9 2.4 15 5.9 0.1 3.2 3 0 0 3 3 3 0 Helix-turn-helix domain DUF972 PF06156.8 EIE90965.1 - 2.8e-05 24.4 2.0 4.5e-05 23.7 1.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF972) TSC22 PF01166.13 EIE90965.1 - 6.3e-05 22.8 1.2 0.00013 21.8 0.8 1.4 1 0 0 1 1 1 1 TSC-22/dip/bun family DUF904 PF06005.7 EIE90965.1 - 0.0067 16.6 1.8 0.011 15.9 1.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF904) DUF947 PF06102.7 EIE90965.1 - 0.037 13.8 0.2 0.037 13.8 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF947) Syntaxin PF00804.20 EIE90965.1 - 0.059 13.5 0.7 0.091 12.9 0.5 1.4 1 0 0 1 1 1 0 Syntaxin DivIC PF04977.10 EIE90965.1 - 0.086 12.3 1.0 0.15 11.5 0.7 1.4 1 0 0 1 1 1 0 Septum formation initiator Spc24 PF08286.6 EIE90965.1 - 0.11 12.2 0.7 0.18 11.5 0.2 1.5 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 bZIP_1 PF00170.16 EIE90965.1 - 0.11 12.4 2.0 0.25 11.3 1.4 1.5 1 0 0 1 1 1 0 bZIP transcription factor Med9 PF07544.8 EIE90965.1 - 0.27 10.9 2.4 0.71 9.6 1.7 1.7 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 DUF4200 PF13863.1 EIE90965.1 - 0.42 10.5 4.7 0.73 9.7 3.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DUF2216 PF10226.4 EIE90965.1 - 0.42 10.0 3.2 0.58 9.6 1.5 1.4 1 1 0 1 1 1 0 Uncharacterized conserved proteins (DUF2216) Amidase02_C PF12123.3 EIE90968.1 - 0.11 12.2 0.2 0.44 10.2 0.1 1.9 1 1 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase DDE_1 PF03184.14 EIE90970.1 - 6.7e-24 84.2 0.4 1.4e-23 83.2 0.3 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EIE90970.1 - 0.0025 17.5 0.0 0.0063 16.2 0.0 1.7 1 1 0 1 1 1 1 DDE superfamily endonuclease Band_7 PF01145.20 EIE90971.1 - 2.9e-24 85.9 5.1 3.5e-24 85.6 3.2 1.4 1 1 0 1 1 1 1 SPFH domain / Band 7 family DUF3811 PF11656.3 EIE90971.1 - 0.22 11.5 2.6 0.44 10.6 1.4 1.8 1 1 0 1 1 1 0 YjbD family (DUF3811) HTH_29 PF13551.1 EIE90972.1 - 0.00046 20.3 0.0 0.00048 20.2 0.0 1.0 1 0 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.1 EIE90972.1 - 0.0038 17.9 0.1 0.006 17.3 0.1 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.1 EIE90972.1 - 0.03 14.3 0.1 0.034 14.1 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.1 EIE90972.1 - 0.14 12.4 0.0 0.16 12.2 0.0 1.2 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 Ribosomal_L50 PF10501.4 EIE90973.1 - 0.013 15.4 0.1 0.024 14.5 0.1 1.5 1 1 0 1 1 1 0 Ribosomal subunit 39S VHS PF00790.14 EIE90975.1 - 4.9e-42 142.8 1.0 1.1e-41 141.7 0.0 2.1 2 0 0 2 2 2 1 VHS domain FYVE PF01363.16 EIE90975.1 - 9.1e-11 41.4 2.7 1.6e-10 40.6 1.9 1.3 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.15 EIE90975.1 - 4.8e-07 28.7 5.1 0.0027 17.1 0.8 2.7 2 0 0 2 2 2 2 Ubiquitin interaction motif Hrs_helical PF12210.3 EIE90975.1 - 0.002 18.3 0.2 0.004 17.3 0.1 1.4 1 0 0 1 1 1 1 Hepatocyte growth factor-regulated tyrosine kinase substrate FYVE_2 PF02318.11 EIE90975.1 - 0.04 13.8 0.9 0.087 12.7 0.6 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger Viral_env_E26 PF11050.3 EIE90975.1 - 0.21 10.7 1.0 2.5 7.2 0.1 2.2 2 0 0 2 2 2 0 Virus envelope protein E26 DUF2262 PF10020.4 EIE90976.1 - 0.023 14.9 0.6 0.067 13.3 0.2 1.8 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2262) DDE_3 PF13358.1 EIE90978.1 - 1.1e-11 44.6 0.1 1.1e-11 44.6 0.1 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease IP_trans PF02121.13 EIE90979.1 - 8.1e-97 323.3 1.7 9.2e-97 323.1 1.2 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein Polysacc_deac_1 PF01522.16 EIE90980.1 - 1.3e-23 82.9 0.0 2.1e-23 82.3 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase C2 PF00168.25 EIE90981.1 - 4.3e-55 183.5 0.8 3.1e-19 68.5 0.0 5.6 5 0 0 5 5 5 5 C2 domain Ribosomal_S17e PF00833.13 EIE90982.1 - 1.8e-60 202.0 0.4 2.2e-60 201.7 0.3 1.1 1 0 0 1 1 1 1 Ribosomal S17 MBOAT PF03062.14 EIE90983.1 - 4.3e-38 131.2 18.1 5.8e-38 130.8 12.5 1.2 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family SCAMP PF04144.8 EIE90984.1 - 1.5e-39 135.6 13.1 1.8e-39 135.4 9.1 1.1 1 0 0 1 1 1 1 SCAMP family DUF3552 PF12072.3 EIE90984.1 - 0.004 16.4 5.1 0.0077 15.4 3.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) OmpH PF03938.9 EIE90984.1 - 0.0068 16.3 0.5 0.011 15.6 0.4 1.3 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) DUF106 PF01956.11 EIE90984.1 - 0.14 11.7 2.8 0.49 9.9 0.0 2.8 3 1 0 3 3 3 0 Integral membrane protein DUF106 Fructosamin_kin PF03881.9 EIE90984.1 - 1.2 7.9 6.1 2.1 7.2 4.2 1.2 1 0 0 1 1 1 0 Fructosamine kinase Peptidase_M28 PF04389.12 EIE90985.1 - 2.8e-36 124.9 0.0 4.6e-36 124.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EIE90985.1 - 3e-08 33.3 0.0 5.4e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 EIE90985.1 - 0.00019 20.3 0.0 0.0027 16.5 0.0 2.4 1 1 1 2 2 2 1 M42 glutamyl aminopeptidase NADH-u_ox-rdase PF10785.4 EIE90986.1 - 4.6e-31 106.9 0.5 6.4e-31 106.4 0.4 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.2 EIE90986.1 - 1e-20 73.2 0.1 1.4e-20 72.7 0.0 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit Spond_N PF06468.8 EIE90986.1 - 0.02 14.5 0.2 0.11 12.1 0.1 1.9 1 1 0 1 1 1 0 Spondin_N Mcp5_PH PF12814.2 EIE90987.1 - 4.2e-29 100.9 0.2 1.5e-28 99.1 0.1 2.1 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology CENP-F_leu_zip PF10473.4 EIE90987.1 - 0.0094 15.8 3.2 0.0094 15.8 2.2 4.9 4 1 1 5 5 5 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 EIE90987.1 - 1.4 8.0 16.5 0.092 11.9 4.5 3.1 3 0 0 3 3 3 0 Reovirus sigma C capsid protein MFS_1 PF07690.11 EIE90988.1 - 2.5e-14 52.7 37.0 5.1e-14 51.7 24.7 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.11 EIE90988.1 - 5.9e-10 38.8 5.8 5.9e-10 38.8 4.0 2.2 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 LAB_N PF07578.6 EIE90988.1 - 0.098 12.5 8.9 0.29 11.0 0.1 3.6 3 0 0 3 3 3 0 Lipid A Biosynthesis N-terminal domain Arrestin_C PF02752.17 EIE90990.1 - 1.4e-17 64.1 0.0 4.5e-14 52.7 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EIE90990.1 - 1.7e-11 44.1 0.5 4.5e-11 42.7 0.0 1.9 3 0 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 EIE90990.1 - 1.3e-05 24.8 0.0 2.1e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Arrestin_N terminal like Engrail_1_C_sig PF10525.4 EIE90991.1 - 0.24 10.5 1.4 7.4 5.7 0.0 2.5 2 0 0 2 2 2 0 Engrailed homeobox C-terminal signature domain PH PF00169.24 EIE90992.1 - 8.1e-06 25.9 0.2 1.9e-05 24.7 0.2 1.7 1 1 0 1 1 1 1 PH domain Viral_DNA_bi PF02236.12 EIE90992.1 - 0.079 13.1 0.1 0.2 11.8 0.1 1.8 1 1 0 1 1 1 0 Viral DNA-binding protein, all alpha domain Ribosomal_L13 PF00572.13 EIE90993.1 - 3e-25 88.7 0.0 5.1e-25 87.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L13 WD40 PF00400.27 EIE90994.1 - 3.3e-10 39.4 0.0 1.4 8.9 0.0 5.7 6 0 0 6 6 6 5 WD domain, G-beta repeat NatB_MDM20 PF09797.4 EIE90995.1 - 5.1e-61 206.4 21.7 1e-60 205.4 10.9 2.9 2 1 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit Glyco_hydro_4C PF11975.3 EIE90995.1 - 0.21 11.3 4.3 0.36 10.5 0.2 3.1 3 0 0 3 3 3 0 Family 4 glycosyl hydrolase C-terminal domain TPR_19 PF14559.1 EIE90995.1 - 5.9 7.2 8.6 48 4.3 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat IBN_N PF03810.14 EIE90996.1 - 1.3e-14 53.8 0.0 9.8e-14 51.0 0.0 2.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain DnaJ PF00226.26 EIE90997.1 - 2.7e-14 52.6 0.1 3.1e-14 52.4 0.1 1.1 1 0 0 1 1 1 1 DnaJ domain RVT_1 PF00078.22 EIE90998.1 - 5.3e-33 114.1 0.0 7.6e-33 113.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.18 EIE90999.1 - 2.2e-06 27.3 9.0 0.0007 19.3 0.4 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 EIE90999.1 - 0.0011 18.5 2.5 0.16 11.6 0.1 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.1 EIE90999.1 - 0.0035 16.7 4.1 0.015 14.7 0.7 2.4 1 1 1 2 2 2 1 Zinc knuckle RRM_1 PF00076.17 EIE90999.1 - 0.064 12.9 0.0 0.31 10.7 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE90999.1 - 0.072 13.0 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Cmc1 PF08583.5 EIE90999.1 - 0.59 9.9 3.3 1.1 9.1 2.3 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like zf-CCHC_6 PF15288.1 EIE90999.1 - 3 7.5 12.6 3.3 7.4 1.3 2.9 2 1 1 3 3 3 0 Zinc knuckle RVT_1 PF00078.22 EIE91000.1 - 4.6e-36 124.1 0.0 1e-35 123.0 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.18 EIE91001.1 - 1.8e-05 24.4 10.5 0.0025 17.6 1.0 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 EIE91001.1 - 0.044 13.4 8.2 0.039 13.6 1.3 2.4 2 0 0 2 2 2 0 Zinc knuckle Zn_ribbon_2 PF12674.2 EIE91001.1 - 2.9 8.3 8.2 11 6.4 0.9 2.5 1 1 1 2 2 2 0 Putative zinc ribbon domain DDE_3 PF13358.1 EIE91002.1 - 6.6e-09 35.6 0.0 1.4e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_28 PF13518.1 EIE91002.1 - 5.7e-08 32.6 2.2 1.7e-06 27.8 0.0 2.7 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_23 PF13384.1 EIE91002.1 - 2e-07 30.4 1.9 2.5e-05 23.7 0.0 2.8 3 0 0 3 3 3 2 Homeodomain-like domain HTH_29 PF13551.1 EIE91002.1 - 3.5e-07 30.3 0.0 9.8e-07 28.9 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn helix HTH_17 PF12728.2 EIE91002.1 - 8.7e-06 25.8 0.0 0.098 12.9 0.0 2.6 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_32 PF13565.1 EIE91002.1 - 5.9e-05 23.7 0.1 0.00024 21.8 0.0 2.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_Tnp_1 PF01527.15 EIE91002.1 - 0.005 16.7 0.1 0.005 16.7 0.1 2.2 4 0 0 4 4 4 1 Transposase HTH_Tnp_ISL3 PF13542.1 EIE91002.1 - 0.028 13.6 0.0 0.061 12.5 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_30 PF13556.1 EIE91002.1 - 0.073 12.6 0.0 0.28 10.7 0.0 1.9 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain LZ_Tnp_IS481 PF13011.1 EIE91002.1 - 0.09 13.1 0.1 0.28 11.5 0.0 1.8 2 0 0 2 2 2 0 leucine-zipper of insertion element IS481 DUF4098 PF13345.1 EIE91003.1 - 1.3e-08 34.6 41.1 0.004 17.0 8.0 3.6 1 1 1 2 2 2 2 Domain of unknown function (DUF4098) Prosystemin PF07376.6 EIE91003.1 - 1.5e-05 24.4 33.2 0.042 13.2 4.2 3.7 1 1 2 3 3 3 3 Prosystemin Fil_haemagg_2 PF13332.1 EIE91003.1 - 0.36 10.6 38.0 2 8.1 18.9 3.6 1 1 1 2 2 2 0 Haemagluttinin repeat AsmA_2 PF13502.1 EIE91003.1 - 4 6.7 25.8 1.2e+04 -4.7 17.9 3.9 1 1 0 1 1 1 0 AsmA-like C-terminal region DUF4098 PF13345.1 EIE91004.1 - 0.009 15.9 22.8 0.036 13.9 12.3 3.0 2 1 0 2 2 2 1 Domain of unknown function (DUF4098) Prosystemin PF07376.6 EIE91004.1 - 0.025 13.9 16.6 0.097 12.0 5.5 2.5 1 1 1 2 2 2 0 Prosystemin Fil_haemagg_2 PF13332.1 EIE91004.1 - 1.7 8.4 22.1 13 5.4 2.8 2.8 2 1 0 2 2 2 0 Haemagluttinin repeat DDE_3 PF13358.1 EIE91005.1 - 6.6e-09 35.6 0.0 1.4e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_28 PF13518.1 EIE91005.1 - 5.7e-08 32.6 2.2 1.7e-06 27.8 0.0 2.7 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_23 PF13384.1 EIE91005.1 - 2e-07 30.4 1.9 2.5e-05 23.7 0.0 2.8 3 0 0 3 3 3 2 Homeodomain-like domain HTH_29 PF13551.1 EIE91005.1 - 3.5e-07 30.3 0.0 9.8e-07 28.9 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn helix HTH_17 PF12728.2 EIE91005.1 - 8.7e-06 25.8 0.0 0.098 12.9 0.0 2.6 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_32 PF13565.1 EIE91005.1 - 5.9e-05 23.7 0.1 0.00024 21.8 0.0 2.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_Tnp_1 PF01527.15 EIE91005.1 - 0.005 16.7 0.1 0.005 16.7 0.1 2.2 4 0 0 4 4 4 1 Transposase HTH_Tnp_ISL3 PF13542.1 EIE91005.1 - 0.028 13.6 0.0 0.061 12.5 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_30 PF13556.1 EIE91005.1 - 0.073 12.6 0.0 0.28 10.7 0.0 1.9 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain LZ_Tnp_IS481 PF13011.1 EIE91005.1 - 0.09 13.1 0.1 0.28 11.5 0.0 1.8 2 0 0 2 2 2 0 leucine-zipper of insertion element IS481 zf-RVT PF13966.1 EIE91007.1 - 0.0071 16.6 1.2 0.022 15.0 0.5 2.1 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase zf-CCHC PF00098.18 EIE91008.1 - 2.2e-06 27.3 9.0 0.0007 19.3 0.4 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 EIE91008.1 - 0.0011 18.5 2.5 0.16 11.6 0.1 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.1 EIE91008.1 - 0.0036 16.7 4.1 0.015 14.7 0.7 2.3 1 1 1 2 2 2 1 Zinc knuckle RRM_1 PF00076.17 EIE91008.1 - 0.064 12.9 0.0 0.31 10.7 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE91008.1 - 0.072 13.0 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Cmc1 PF08583.5 EIE91008.1 - 0.59 9.9 3.3 1.1 9.1 2.3 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like zf-CCHC_6 PF15288.1 EIE91008.1 - 3 7.5 12.6 3.3 7.4 1.3 2.9 2 1 1 3 3 3 0 Zinc knuckle Mcm10 PF09332.6 EIE91009.1 - 0.16 11.2 2.5 0.17 11.1 1.8 1.1 1 0 0 1 1 1 0 Mcm10 replication factor B56 PF01603.15 EIE91010.1 - 8.8e-80 268.3 6.7 3.6e-66 223.4 1.3 2.2 1 1 1 2 2 2 2 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.2 EIE91010.1 - 0.018 14.5 0.4 2.6 7.4 0.1 3.1 2 1 1 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Sulfotransfer_3 PF13469.1 EIE91011.1 - 0.00017 22.5 0.2 0.00032 21.6 0.1 1.4 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.22 EIE91011.1 - 0.023 13.9 0.0 0.068 12.4 0.0 1.9 1 1 0 1 1 1 0 Sulfotransferase domain AhpC-TSA PF00578.16 EIE91012.1 - 2.3e-35 120.9 0.0 3.2e-35 120.5 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EIE91012.1 - 3.1e-13 49.5 0.0 4.2e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 EIE91012.1 - 6.4e-13 48.1 0.0 1.1e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.9 EIE91012.1 - 0.095 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 SCO1/SenC tRNA-synt_1_2 PF13603.1 EIE91013.1 - 3e-57 192.9 0.0 5.7e-57 192.0 0.0 1.5 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1 PF00133.17 EIE91013.1 - 1.9e-52 178.1 0.0 6.3e-25 87.2 0.0 4.2 1 1 2 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EIE91013.1 - 3.8e-20 71.9 0.0 4.1e-14 52.0 0.0 4.1 3 1 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EIE91013.1 - 4.4e-17 62.2 1.3 8.3e-17 61.3 0.1 2.1 3 0 0 3 3 3 1 Anticodon-binding domain of tRNA tRNA-synt_1d PF00750.14 EIE91013.1 - 0.015 14.1 0.0 0.029 13.2 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (R) Reovirus_cap PF00979.12 EIE91013.1 - 0.035 13.0 0.0 0.058 12.3 0.0 1.2 1 0 0 1 1 1 0 Reovirus outer capsid protein, Sigma 3 Clr5 PF14420.1 EIE91013.1 - 0.069 13.0 0.2 0.21 11.5 0.1 1.7 1 0 0 1 1 1 0 Clr5 domain MoCF_biosynth PF00994.19 EIE91014.1 - 1e-60 203.3 0.3 8.2e-30 103.0 0.0 2.4 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.12 EIE91014.1 - 9.5e-35 119.3 1.8 1.5e-34 118.7 1.2 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.10 EIE91014.1 - 2.4e-13 49.8 0.0 5.6e-13 48.6 0.0 1.7 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) NAD_binding_4 PF07993.7 EIE91015.1 - 1.2e-21 76.8 0.0 2.3e-16 59.4 0.0 2.5 1 1 1 2 2 2 2 Male sterility protein Acyltransferase PF01553.16 EIE91015.1 - 6.1e-06 25.6 0.0 1.4e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase ABC_membrane PF00664.18 EIE91016.1 - 3e-105 351.5 27.4 3.3e-55 187.4 11.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EIE91016.1 - 2.9e-71 238.1 0.0 3.2e-35 121.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EIE91016.1 - 8.9e-16 57.7 0.1 7.2e-07 28.6 0.0 4.2 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.4 EIE91016.1 - 5.8e-11 41.6 0.7 1.5e-05 23.7 0.1 2.9 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_21 PF13304.1 EIE91016.1 - 2.5e-10 40.7 0.0 0.14 12.0 0.0 4.6 4 0 0 4 4 4 2 AAA domain AAA_22 PF13401.1 EIE91016.1 - 2.3e-08 34.2 0.2 0.034 14.2 0.0 4.2 4 1 0 4 4 3 2 AAA domain AAA_16 PF13191.1 EIE91016.1 - 3e-08 33.8 3.1 0.0085 16.1 0.0 3.5 2 2 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EIE91016.1 - 4e-07 29.4 0.7 0.023 14.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EIE91016.1 - 9.4e-07 28.1 0.0 0.027 13.6 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA PF00004.24 EIE91016.1 - 3.4e-06 27.2 1.6 1.8 8.7 0.0 4.6 4 1 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EIE91016.1 - 3.5e-06 27.8 0.0 0.11 13.2 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 EIE91016.1 - 8.2e-06 25.5 0.6 0.68 9.4 0.1 4.1 2 2 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EIE91016.1 - 6.6e-05 22.8 0.0 0.5 10.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 EIE91016.1 - 0.00012 21.9 3.2 0.22 11.4 0.2 3.8 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit G-alpha PF00503.15 EIE91016.1 - 0.00026 19.8 0.9 0.8 8.3 0.0 2.8 3 1 0 3 3 3 2 G-protein alpha subunit MobB PF03205.9 EIE91016.1 - 0.00053 19.7 0.1 0.95 9.1 0.0 2.8 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 EIE91016.1 - 0.00057 19.0 0.1 0.31 10.1 0.0 3.0 3 0 0 3 3 3 1 Zeta toxin AAA_10 PF12846.2 EIE91016.1 - 0.00068 19.1 3.1 0.75 9.1 0.1 3.4 3 1 0 3 3 3 1 AAA-like domain AAA_14 PF13173.1 EIE91016.1 - 0.0029 17.5 0.0 4.5 7.2 0.0 3.3 4 0 0 4 4 3 0 AAA domain Rad17 PF03215.10 EIE91016.1 - 0.003 16.3 0.1 0.12 11.0 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein RNA_helicase PF00910.17 EIE91016.1 - 0.0049 17.0 0.1 4.3 7.5 0.0 3.0 2 1 0 2 2 2 0 RNA helicase AAA_25 PF13481.1 EIE91016.1 - 0.0059 16.0 0.2 6.3 6.1 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.9 EIE91016.1 - 0.0075 15.9 0.3 9.2 5.9 0.0 3.4 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EIE91016.1 - 0.01 16.1 2.0 5.9 7.2 0.0 3.6 4 0 0 4 4 2 0 AAA domain AAA_28 PF13521.1 EIE91016.1 - 0.01 15.8 0.1 2.2 8.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.17 EIE91016.1 - 0.012 15.1 0.0 1 8.7 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain APS_kinase PF01583.15 EIE91016.1 - 0.016 14.8 0.0 5.1 6.7 0.0 3.4 3 0 0 3 3 3 0 Adenylylsulphate kinase AAA_19 PF13245.1 EIE91016.1 - 0.04 13.6 1.9 3.9 7.3 0.0 3.4 3 0 0 3 3 3 0 Part of AAA domain GMC_oxred_N PF00732.14 EIE91016.1 - 0.071 12.2 0.3 0.68 9.0 0.0 2.5 3 0 0 3 3 3 0 GMC oxidoreductase ATP_bind_1 PF03029.12 EIE91016.1 - 0.071 12.6 0.0 6.8 6.1 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NACHT PF05729.7 EIE91016.1 - 0.075 12.6 0.2 13 5.3 0.1 2.6 2 0 0 2 2 2 0 NACHT domain MMR_HSR1 PF01926.18 EIE91016.1 - 0.088 12.7 0.1 15 5.5 0.0 3.1 3 0 0 3 3 2 0 50S ribosome-binding GTPase Nuc_deoxyrib_tr PF05014.10 EIE91016.1 - 0.12 12.2 0.3 35 4.3 0.0 3.2 2 1 0 2 2 2 0 Nucleoside 2-deoxyribosyltransferase Synapsin_N PF10581.4 EIE91016.1 - 0.17 11.7 0.0 29 4.5 0.0 2.4 2 0 0 2 2 2 0 Synapsin N-terminal DUF2207 PF09972.4 EIE91016.1 - 0.4 9.2 0.0 0.4 9.2 0.0 3.0 4 0 0 4 4 4 0 Predicted membrane protein (DUF2207) DUF4131 PF13567.1 EIE91016.1 - 1.5 8.1 10.1 13 5.1 0.0 4.4 5 0 0 5 5 4 0 Domain of unknown function (DUF4131) Ribosomal_L2_C PF03947.13 EIE91017.1 - 3.4e-42 143.3 2.3 3.4e-42 143.3 1.6 1.5 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EIE91017.1 - 1.8e-15 56.6 0.1 4.4e-15 55.4 0.1 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain BolA PF01722.13 EIE91018.1 - 1.5e-17 63.2 0.0 2e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 BolA-like protein PPR_2 PF13041.1 EIE91019.1 - 4e-43 145.1 6.5 5.4e-13 48.7 0.0 14.4 10 2 5 15 15 15 9 PPR repeat family PPR PF01535.15 EIE91019.1 - 9.9e-36 119.2 5.5 2.5e-05 23.9 0.0 15.6 17 1 1 18 18 18 5 PPR repeat PPR_3 PF13812.1 EIE91019.1 - 8.2e-31 103.6 8.5 0.00025 21.0 0.0 13.4 15 1 1 16 16 13 5 Pentatricopeptide repeat domain PPR_1 PF12854.2 EIE91019.1 - 1.1e-23 82.3 2.5 3.1e-05 23.3 0.0 9.8 10 0 0 10 10 10 5 PPR repeat TPR_19 PF14559.1 EIE91019.1 - 1.4e-07 31.7 2.1 0.03 14.6 0.1 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.1 EIE91019.1 - 1.4e-06 28.8 0.0 1.6 9.4 0.0 7.4 8 1 2 10 10 9 1 Tetratricopeptide repeat TPR_14 PF13428.1 EIE91019.1 - 4.7e-06 26.7 4.8 1.7 9.5 0.0 7.9 10 1 1 11 11 6 1 Tetratricopeptide repeat Apc3 PF12895.2 EIE91019.1 - 5.1e-05 23.3 4.0 1.9 8.6 0.0 5.3 7 0 0 7 7 5 2 Anaphase-promoting complex, cyclosome, subunit 3 RPM2 PF08579.6 EIE91019.1 - 8.6e-05 22.6 0.7 2.7 8.1 0.0 4.8 4 1 0 4 4 4 2 Mitochondrial ribonuclease P subunit (RPM2) TPR_7 PF13176.1 EIE91019.1 - 0.0013 18.3 7.7 17 5.5 0.2 6.6 8 0 0 8 8 6 0 Tetratricopeptide repeat ATP13 PF12921.2 EIE91019.1 - 0.011 15.0 0.4 17 4.8 0.0 4.2 4 0 0 4 4 4 0 Mitochondrial ATPase expression TPR_2 PF07719.12 EIE91019.1 - 0.029 14.2 6.7 21 5.3 0.0 6.0 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 EIE91019.1 - 0.25 11.8 10.2 23 5.7 0.1 6.8 9 0 0 9 9 6 0 Tetratricopeptide repeat TPR_10 PF13374.1 EIE91019.1 - 1.2 9.1 6.0 13 5.9 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat vATP-synt_E PF01991.13 EIE91020.1 - 1.6e-42 145.0 12.4 1.8e-42 144.8 8.6 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Sec2p PF06428.6 EIE91020.1 - 0.69 9.7 11.5 0.069 13.0 0.7 2.3 1 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p RNA_pol_Rpb1_5 PF04998.12 EIE91020.1 - 1 8.5 4.1 1.7 7.8 2.8 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 V_ATPase_I PF01496.14 EIE91020.1 - 3.5 5.3 7.6 4.3 5.0 5.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family WD40 PF00400.27 EIE91022.1 - 1.9e-56 186.0 20.7 6.3e-10 38.5 0.0 7.8 9 0 0 9 9 9 6 WD domain, G-beta repeat F-box-like PF12937.2 EIE91022.1 - 1.1e-10 41.0 0.2 2.3e-10 40.0 0.1 1.6 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 EIE91022.1 - 5.3e-08 31.4 13.4 0.018 13.2 0.1 5.6 1 1 5 6 6 6 4 Nucleoporin Nup120/160 F-box PF00646.28 EIE91022.1 - 0.00021 20.8 0.1 0.00045 19.7 0.0 1.6 1 0 0 1 1 1 1 F-box domain Nucleoporin_N PF08801.6 EIE91022.1 - 0.00045 19.0 0.9 0.29 9.8 0.1 2.5 1 1 1 2 2 2 2 Nup133 N terminal like eIF2A PF08662.6 EIE91022.1 - 0.0057 16.3 0.0 0.11 12.1 0.0 2.7 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A MgtE_N PF03448.12 EIE91022.1 - 0.045 14.0 0.0 0.079 13.2 0.0 1.4 1 0 0 1 1 1 0 MgtE intracellular N domain PRANC PF09372.5 EIE91022.1 - 0.085 12.8 0.1 0.28 11.1 0.0 1.9 1 0 0 1 1 1 0 PRANC domain PQQ_3 PF13570.1 EIE91022.1 - 0.14 12.4 1.3 4 7.8 0.0 3.8 5 1 0 5 5 5 0 PQQ-like domain NTF2 PF02136.15 EIE91023.1 - 1.7e-28 99.3 0.9 3e-28 98.5 0.1 1.9 2 0 0 2 2 2 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.17 EIE91023.1 - 5.9e-12 45.0 0.0 1.3e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE91023.1 - 1.6e-08 34.3 0.0 3.3e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE91023.1 - 1.2e-05 25.0 0.0 2.5e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EIE91023.1 - 0.06 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Hexokinase_2 PF03727.11 EIE91024.1 - 1.3e-45 155.4 0.2 1.9e-45 154.9 0.1 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EIE91024.1 - 5.6e-36 123.8 0.0 8.2e-36 123.2 0.0 1.2 1 0 0 1 1 1 1 Hexokinase PIP5K PF01504.13 EIE91026.1 - 5.5e-36 123.9 0.9 1e-35 123.0 0.2 1.6 1 1 1 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase MCM2_N PF12619.3 EIE91026.1 - 0.024 14.6 2.4 0.041 13.8 1.7 1.4 1 0 0 1 1 1 0 Mini-chromosome maintenance protein 2 CRAL_TRIO PF00650.15 EIE91027.1 - 4.1e-33 114.1 0.1 7.6e-33 113.2 0.1 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EIE91027.1 - 3.6e-11 43.0 0.0 1.1e-10 41.4 0.0 2.0 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EIE91027.1 - 3.6e-08 33.4 0.0 6.2e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain PRA-CH PF01502.13 EIE91027.1 - 0.14 11.8 0.1 0.27 10.8 0.1 1.4 1 0 0 1 1 1 0 Phosphoribosyl-AMP cyclohydrolase Trehalase PF01204.13 EIE91028.1 - 8e-178 592.2 1.6 9.8e-178 591.9 1.1 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 EIE91028.1 - 4.6e-14 51.4 1.0 9e-14 50.4 0.7 1.5 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain YvbH_ext PF11724.3 EIE91028.1 - 0.0051 16.4 0.2 2.9 7.6 0.0 3.3 3 0 0 3 3 3 2 YvbH-like oligomerisation region DUF4259 PF14078.1 EIE91028.1 - 0.078 13.4 3.5 6 7.3 0.6 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4259) DEAD PF00270.24 EIE91029.1 - 2.6e-37 127.9 0.2 5e-37 126.9 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIE91029.1 - 2.5e-26 91.3 0.0 1.8e-25 88.6 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIE91029.1 - 0.0014 18.5 0.1 0.0014 18.5 0.0 2.2 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 EIE91029.1 - 0.0024 16.9 0.0 0.0051 15.9 0.0 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit CUE PF02845.11 EIE91030.1 - 0.027 13.9 0.0 0.047 13.1 0.0 1.4 1 0 0 1 1 1 0 CUE domain DDE_Tnp_IS1595 PF12762.2 EIE91032.1 - 3.2e-14 53.0 2.2 7.2e-10 38.8 0.1 2.9 2 1 0 2 2 2 2 ISXO2-like transposase domain DnaJ PF00226.26 EIE91033.1 - 6e-16 57.9 0.0 8.1e-16 57.5 0.0 1.1 1 0 0 1 1 1 1 DnaJ domain HTH_Tnp_Tc3_2 PF01498.13 EIE91034.1 - 4.9e-06 26.5 0.2 6.9e-06 26.0 0.1 1.3 1 0 0 1 1 1 1 Transposase DUF445 PF04286.7 EIE91035.1 - 0.034 13.6 0.7 0.045 13.2 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Clathrin PF00637.15 EIE91035.1 - 0.11 12.1 8.4 0.21 11.1 0.0 3.2 2 1 1 3 3 3 0 Region in Clathrin and VPS Apc3 PF12895.2 EIE91035.1 - 0.3 11.2 5.2 1.2 9.2 0.9 3.2 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Vps39_1 PF10366.4 EIE91035.1 - 1 9.4 12.7 0.25 11.3 0.5 3.6 3 2 2 5 5 5 0 Vacuolar sorting protein 39 domain 1 OPA3 PF07047.7 EIE91036.1 - 2.7e-17 62.8 0.1 3.1e-17 62.6 0.1 1.1 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) MR_MLE_C PF13378.1 EIE91037.1 - 5.9e-17 61.6 0.0 1.4e-16 60.3 0.0 1.7 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 EIE91037.1 - 5.6e-15 55.6 0.6 1.1e-13 51.5 0.2 2.4 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 EIE91037.1 - 2.1e-05 24.5 0.0 4.4e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain WD40 PF00400.27 EIE91038.1 - 5.8e-25 86.2 5.6 6.1e-08 32.2 0.0 5.4 6 0 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.6 EIE91038.1 - 0.029 14.0 0.0 0.12 12.1 0.0 1.9 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Nuc_sug_transp PF04142.10 EIE91039.1 - 2.2e-76 256.1 30.7 3.4e-44 150.7 2.5 2.6 3 0 0 3 3 3 2 Nucleotide-sugar transporter EmrE PF13536.1 EIE91039.1 - 2.2e-07 31.0 1.6 2.2e-07 31.0 1.1 2.7 3 0 0 3 3 3 1 Multidrug resistance efflux transporter UAA PF08449.6 EIE91039.1 - 4.3e-07 29.1 9.9 5.7e-05 22.1 0.3 2.4 2 0 0 2 2 2 2 UAA transporter family EamA PF00892.15 EIE91039.1 - 6.3e-06 26.2 5.3 6.3e-06 26.2 3.7 3.4 3 1 0 3 3 3 1 EamA-like transporter family TPT PF03151.11 EIE91039.1 - 0.00081 19.0 19.4 0.00098 18.7 2.6 3.2 2 2 0 2 2 2 1 Triose-phosphate Transporter family DUF4366 PF14283.1 EIE91039.1 - 0.0042 16.5 0.1 0.0066 15.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) DUF4094 PF13334.1 EIE91039.1 - 0.08 13.3 0.8 0.6 10.5 0.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) CAP_GLY PF01302.20 EIE91040.1 - 4e-07 29.6 0.1 6.5e-07 28.9 0.1 1.3 1 0 0 1 1 1 1 CAP-Gly domain DNA_pol_B_3 PF08408.5 EIE91041.1 - 0.081 12.8 3.1 0.093 12.5 1.1 1.8 1 1 1 2 2 2 0 DNA polymerase family B viral insert SCP2 PF02036.12 EIE91042.1 - 1.1e-23 83.4 1.3 1.3e-23 83.1 0.9 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 EIE91042.1 - 0.00021 21.2 0.3 0.00025 21.0 0.2 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal DUF1700 PF08006.6 EIE91042.1 - 0.048 12.9 0.0 0.059 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) SecA_PP_bind PF01043.15 EIE91042.1 - 0.095 13.0 0.1 0.13 12.6 0.1 1.3 1 1 0 1 1 1 0 SecA preprotein cross-linking domain DUF1410 PF07198.6 EIE91042.1 - 0.19 12.0 1.7 0.5 10.7 1.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1410) DUF721 PF05258.7 EIE91043.1 - 0.094 12.9 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF721) HMG_box PF00505.14 EIE91044.1 - 1.3e-15 57.3 1.8 2.9e-15 56.2 1.2 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EIE91044.1 - 6.7e-11 42.3 1.8 1.4e-10 41.4 1.2 1.5 1 0 0 1 1 1 1 HMG-box domain SAM_1 PF00536.25 EIE91044.1 - 1.9e-09 37.5 1.3 2.6e-09 37.1 0.1 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EIE91044.1 - 3e-07 30.2 1.1 3.9e-07 29.8 0.1 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) NCD1 PF04904.8 EIE91044.1 - 0.00013 21.6 0.0 0.00032 20.3 0.0 1.7 1 0 0 1 1 1 1 NAB conserved region 1 (NCD1) IPP-2 PF04979.9 EIE91045.1 - 0.00078 19.7 3.1 0.00078 19.7 2.2 1.1 1 0 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) Prenyltrans PF00432.16 EIE91046.1 - 1.2e-41 139.9 14.6 1.4e-08 34.1 0.6 5.3 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EIE91046.1 - 4e-23 81.9 0.0 2.3e-17 63.4 0.0 3.6 4 0 0 4 4 4 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 EIE91046.1 - 4e-06 26.8 0.0 0.00026 20.9 0.0 2.5 1 1 1 2 2 2 2 Prenyltransferase-like Ecl1 PF12855.2 EIE91047.1 - 2.1e-08 33.3 0.6 3.4e-08 32.6 0.4 1.3 1 0 0 1 1 1 1 Life-span regulatory factor zf-MYND PF01753.13 EIE91047.1 - 0.0042 16.9 0.3 0.007 16.2 0.2 1.4 1 0 0 1 1 1 1 MYND finger TPR_11 PF13414.1 EIE91049.1 - 4e-55 183.3 34.4 4.7e-17 61.4 1.2 5.6 4 1 1 5 5 5 5 TPR repeat TPR_1 PF00515.23 EIE91049.1 - 8.2e-48 158.1 29.6 3e-08 32.9 0.3 8.5 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_2 PF07719.12 EIE91049.1 - 3e-40 132.9 30.8 9.9e-06 25.1 0.1 9.5 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_16 PF13432.1 EIE91049.1 - 1.3e-28 99.0 21.5 8.3e-09 35.8 0.1 6.4 5 1 2 7 7 7 5 Tetratricopeptide repeat DnaJ PF00226.26 EIE91049.1 - 4.4e-27 93.5 3.9 6.9e-27 92.9 1.5 2.3 2 0 0 2 2 2 1 DnaJ domain TPR_19 PF14559.1 EIE91049.1 - 7.8e-27 93.4 27.4 3.8e-07 30.3 0.8 6.2 5 2 2 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.1 EIE91049.1 - 3.3e-21 73.8 19.6 0.0044 17.5 0.3 8.7 4 3 5 9 9 9 6 Tetratricopeptide repeat TPR_17 PF13431.1 EIE91049.1 - 3.7e-20 70.3 31.7 0.00061 19.7 0.1 10.4 10 3 0 10 10 10 5 Tetratricopeptide repeat TPR_8 PF13181.1 EIE91049.1 - 4.8e-18 63.5 30.0 0.013 15.2 0.2 9.1 8 1 1 9 9 8 7 Tetratricopeptide repeat TPR_12 PF13424.1 EIE91049.1 - 9.5e-18 63.9 31.5 5e-07 29.5 0.9 6.5 3 2 4 7 7 7 5 Tetratricopeptide repeat Apc3 PF12895.2 EIE91049.1 - 1.7e-14 53.6 27.4 2.7e-08 33.8 1.9 5.1 1 1 4 5 5 5 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EIE91049.1 - 3.3e-14 52.4 10.0 0.03 14.1 0.3 5.5 2 2 3 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.1 EIE91049.1 - 3e-08 32.8 15.2 0.0099 15.6 0.0 6.5 6 0 0 6 6 6 3 Tetratricopeptide repeat NARP1 PF12569.3 EIE91049.1 - 1.6e-07 30.4 24.3 0.012 14.4 6.0 4.0 3 1 1 4 4 4 3 NMDA receptor-regulated protein 1 TPR_6 PF13174.1 EIE91049.1 - 3.1e-07 30.3 30.9 0.012 15.9 0.0 8.1 10 1 0 10 10 7 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EIE91049.1 - 4.6e-07 29.6 25.7 0.31 10.9 0.0 8.0 7 1 1 8 8 8 1 Fis1 C-terminal tetratricopeptide repeat TPR_3 PF07720.7 EIE91049.1 - 4.3e-05 23.1 21.2 0.00068 19.3 0.0 6.6 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_10 PF13374.1 EIE91049.1 - 8e-05 22.4 19.4 0.083 12.8 0.1 7.0 7 0 0 7 7 7 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 EIE91049.1 - 0.014 14.6 5.7 3.4 7.0 0.0 4.4 4 0 0 4 4 4 0 SHNi-TPR Alkyl_sulf_dimr PF14863.1 EIE91049.1 - 0.018 15.2 13.7 0.3 11.3 0.0 4.4 1 1 4 5 5 5 0 Alkyl sulfatase dimerisation DUF1895 PF08988.5 EIE91049.1 - 0.021 14.8 0.4 4.4 7.4 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1895) Coatomer_E PF04733.9 EIE91049.1 - 0.065 12.4 12.0 0.64 9.1 0.2 3.9 2 2 2 4 4 4 0 Coatomer epsilon subunit TPR_4 PF07721.9 EIE91049.1 - 0.21 12.0 1.0 1.4e+02 3.4 0.2 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat MIT PF04212.13 EIE91049.1 - 0.72 9.7 22.1 0.79 9.6 0.7 5.4 3 2 2 5 5 5 0 MIT (microtubule interacting and transport) domain DUF4398 PF14346.1 EIE91049.1 - 0.89 9.6 26.6 0.11 12.5 0.4 5.7 4 1 0 5 5 5 0 Domain of unknown function (DUF4398) End3 PF12761.2 EIE91050.1 - 0.018 14.6 0.8 0.031 13.9 0.6 1.3 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 DUF3890 PF13029.1 EIE91050.1 - 0.22 11.5 0.2 0.22 11.5 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3890) DDE_3 PF13358.1 EIE91051.1 - 6e-08 32.5 0.0 4.8e-07 29.6 0.0 2.1 1 1 0 1 1 1 1 DDE superfamily endonuclease DUF1620 PF07774.8 EIE91052.1 - 2.1e-67 226.5 0.0 4.9e-67 225.3 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 EIE91052.1 - 8.7e-08 31.9 1.2 2.8e-05 23.7 0.7 3.1 2 1 0 2 2 2 2 PQQ-like domain Acyl-CoA_dh_1 PF00441.19 EIE91053.1 - 2.2e-35 121.9 1.3 3.2e-35 121.4 0.9 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.23 EIE91053.1 - 4e-19 68.1 0.0 9.1e-19 67.0 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.14 EIE91053.1 - 2.4e-17 62.1 0.1 7.8e-17 60.5 0.1 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EIE91053.1 - 2.7e-11 44.0 0.0 5.9e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EIE91053.1 - 5.1e-07 30.0 0.0 8.8e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain STE PF02200.11 EIE91055.1 - 3.7e-56 188.0 0.1 6.7e-56 187.1 0.1 1.4 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2_4 PF13894.1 EIE91055.1 - 4.4e-10 39.1 13.2 6.2e-05 23.0 0.4 3.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EIE91055.1 - 6.9e-10 38.7 11.9 2.4e-07 30.6 2.1 3.7 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 EIE91055.1 - 1.6e-09 37.5 21.4 3.9e-06 26.8 1.2 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EIE91055.1 - 1.8e-05 24.4 2.1 7.7e-05 22.4 0.5 2.4 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EIE91055.1 - 0.01 15.9 5.5 0.23 11.6 0.4 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Sterol_MT_C PF08498.5 EIE91056.1 - 5.8e-27 93.4 1.0 1.1e-26 92.5 0.7 1.5 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 EIE91056.1 - 2.4e-22 79.2 0.0 7e-22 77.7 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIE91056.1 - 7.9e-20 70.9 0.0 1.3e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIE91056.1 - 6.5e-14 52.1 0.0 1.8e-13 50.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIE91056.1 - 1e-13 51.3 0.1 3.4e-13 49.6 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 EIE91056.1 - 8.4e-12 44.7 0.2 1.7e-11 43.7 0.0 1.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.13 EIE91056.1 - 4.7e-11 42.2 0.0 7.6e-11 41.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EIE91056.1 - 3.8e-10 40.1 0.0 9.3e-10 38.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIE91056.1 - 4.5e-09 36.8 0.0 1.1e-08 35.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIE91056.1 - 1.8e-08 34.4 0.0 5.9e-08 32.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EIE91056.1 - 7.1e-06 25.5 0.0 1.5e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 EIE91056.1 - 0.0068 15.9 0.1 0.036 13.6 0.0 2.0 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.5 EIE91056.1 - 0.011 15.3 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_32 PF13679.1 EIE91056.1 - 0.033 13.8 0.0 0.073 12.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.7 EIE91056.1 - 0.033 13.5 0.0 0.06 12.7 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW O-FucT PF10250.4 EIE91056.1 - 0.051 12.6 0.1 0.073 12.1 0.0 1.3 1 0 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase YoaP PF14268.1 EIE91056.1 - 0.1 11.8 0.0 0.31 10.3 0.0 1.8 1 0 0 1 1 1 0 YoaP-like MutS_V PF00488.16 EIE91057.1 - 5.1e-91 304.2 0.0 8.1e-91 303.5 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EIE91057.1 - 1e-41 142.9 6.9 2.2e-41 141.9 4.8 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EIE91057.1 - 2.1e-23 82.4 0.0 1.1e-22 80.2 0.0 2.1 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.12 EIE91057.1 - 1.8e-15 57.2 0.7 1.7e-14 54.0 0.0 2.9 3 0 0 3 3 3 1 MutS domain II MutS_IV PF05190.13 EIE91057.1 - 2.4e-05 24.4 0.1 7.2e-05 22.8 0.0 1.9 1 0 0 1 1 1 1 MutS family domain IV NTPase_1 PF03266.10 EIE91057.1 - 0.0014 18.3 0.1 2.1 8.0 0.0 3.8 4 0 0 4 4 4 1 NTPase AAA_29 PF13555.1 EIE91057.1 - 0.047 13.2 0.0 0.12 11.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Glyco_transf_15 PF01793.11 EIE91058.1 - 1.1e-130 435.4 15.9 1.3e-130 435.1 11.0 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase IncA PF04156.9 EIE91059.1 - 0.00024 20.7 5.0 0.00032 20.3 3.5 1.3 1 1 0 1 1 1 1 IncA protein Laminin_II PF06009.7 EIE91059.1 - 0.002 17.8 0.7 0.0089 15.7 0.1 1.9 2 0 0 2 2 2 1 Laminin Domain II DUF848 PF05852.6 EIE91059.1 - 0.0028 17.5 1.5 0.0039 17.0 0.7 1.5 1 1 0 1 1 1 1 Gammaherpesvirus protein of unknown function (DUF848) CENP-F_leu_zip PF10473.4 EIE91059.1 - 0.026 14.4 1.9 0.026 14.4 1.3 2.0 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AKNA PF12443.3 EIE91059.1 - 0.026 14.5 1.0 0.85 9.6 0.3 2.3 1 1 0 2 2 2 0 AT-hook-containing transcription factor Bacillus_HBL PF05791.6 EIE91059.1 - 0.032 13.6 1.9 0.053 12.8 1.0 1.6 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) TMCO5 PF14992.1 EIE91059.1 - 0.033 13.3 5.2 0.013 14.6 1.6 1.7 1 1 0 1 1 1 0 TMCO5 family DUF4559 PF15112.1 EIE91059.1 - 0.034 13.3 0.6 0.034 13.3 0.4 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4559) HR1 PF02185.11 EIE91059.1 - 0.035 13.8 1.7 1.1 9.1 0.1 2.7 2 0 0 2 2 2 0 Hr1 repeat V_ATPase_I PF01496.14 EIE91059.1 - 0.061 11.1 1.9 0.062 11.1 1.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF972 PF06156.8 EIE91059.1 - 0.063 13.6 2.6 0.41 11.0 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) UFD1 PF03152.9 EIE91059.1 - 0.064 12.3 0.1 0.11 11.6 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin fusion degradation protein UFD1 Surfac_D-trimer PF09006.6 EIE91059.1 - 0.078 12.7 0.2 0.41 10.4 0.0 2.0 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation FlxA PF14282.1 EIE91059.1 - 0.079 12.9 0.7 0.16 11.9 0.5 1.8 1 1 0 1 1 1 0 FlxA-like protein T4SS PF07996.6 EIE91059.1 - 0.086 12.6 0.2 0.16 11.8 0.1 1.5 2 0 0 2 2 2 0 Type IV secretion system proteins Tup_N PF08581.5 EIE91059.1 - 0.11 12.6 4.3 2.1 8.5 0.1 2.5 2 1 0 2 2 2 0 Tup N-terminal HALZ PF02183.13 EIE91059.1 - 0.18 11.5 2.2 12 5.7 0.0 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper Rab5-bind PF09311.6 EIE91059.1 - 0.18 11.6 2.5 1.1 9.0 1.8 2.1 1 1 0 1 1 1 0 Rabaptin-like protein Med9 PF07544.8 EIE91059.1 - 0.43 10.3 4.7 1.7 8.4 0.5 2.7 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 GrpE PF01025.14 EIE91059.1 - 0.5 9.8 3.5 0.45 10.0 1.6 1.6 1 1 1 2 2 2 0 GrpE TPR_MLP1_2 PF07926.7 EIE91059.1 - 0.55 9.9 4.1 0.65 9.7 2.0 2.0 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein GAS PF13851.1 EIE91059.1 - 2.2 7.4 7.3 0.4 9.8 2.1 1.9 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DivIC PF04977.10 EIE91059.1 - 8.5 5.9 8.1 0.6 9.6 0.6 2.5 2 1 1 3 3 2 0 Septum formation initiator p450 PF00067.17 EIE91060.1 - 4.3e-18 65.0 0.1 5.1e-18 64.8 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 Luteo_coat PF00894.13 EIE91060.1 - 0.042 13.6 0.0 0.059 13.1 0.0 1.2 1 0 0 1 1 1 0 Luteovirus coat protein HTH_39 PF14090.1 EIE91061.1 - 0.087 12.3 0.1 0.69 9.4 0.0 2.3 3 0 0 3 3 3 0 Helix-turn-helix domain SRF-TF PF00319.13 EIE91062.1 - 5.5e-21 73.5 0.1 9.5e-21 72.7 0.0 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) CNF1 PF05785.7 EIE91062.1 - 0.061 12.2 0.2 0.096 11.5 0.2 1.3 1 0 0 1 1 1 0 Rho-activating domain of cytotoxic necrotizing factor Histone PF00125.19 EIE91064.1 - 6.4e-22 77.4 0.0 8.1e-22 77.1 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EIE91064.1 - 0.00079 19.4 0.0 0.0011 18.9 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Myosin_head PF00063.16 EIE91065.1 - 3.3e-234 779.0 1.2 5.2e-234 778.3 0.8 1.3 1 1 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 EIE91065.1 - 1.3e-42 145.4 0.0 1.9e-42 144.8 0.0 1.3 1 0 0 1 1 1 1 Myosin tail SH3_1 PF00018.23 EIE91065.1 - 2.8e-15 55.4 1.1 7.7e-15 54.0 0.8 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EIE91065.1 - 4.3e-13 48.6 0.6 9.7e-13 47.4 0.1 1.9 2 0 0 2 2 1 1 Variant SH3 domain SH3_2 PF07653.12 EIE91065.1 - 7e-12 44.6 0.1 3e-11 42.6 0.1 2.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 EIE91065.1 - 2.3e-05 24.4 0.4 5.5e-05 23.2 0.2 1.6 1 0 0 1 1 1 1 Bacterial SH3 domain AAA_22 PF13401.1 EIE91065.1 - 0.0037 17.3 0.1 0.014 15.5 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_17 PF13207.1 EIE91065.1 - 0.015 16.1 0.0 0.059 14.1 0.0 2.1 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EIE91065.1 - 0.017 14.2 0.0 0.033 13.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.1 EIE91065.1 - 0.023 14.6 0.0 0.061 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Hpr_kinase_C PF07475.7 EIE91065.1 - 0.058 12.7 0.4 4.1 6.6 0.0 2.4 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain IQ PF00612.22 EIE91065.1 - 0.058 13.0 9.6 0.23 11.1 0.8 3.3 3 0 0 3 3 2 0 IQ calmodulin-binding motif AAA_18 PF13238.1 EIE91065.1 - 0.059 13.6 0.0 0.24 11.7 0.0 2.2 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EIE91065.1 - 0.093 12.3 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Ribosomal_L32e PF01655.13 EIE91066.1 - 2.3e-47 159.5 1.5 2.8e-47 159.3 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 NADH_B2 PF14813.1 EIE91067.1 - 0.0024 17.5 0.6 0.0025 17.4 0.4 1.2 1 0 0 1 1 1 1 NADH dehydrogenase 1 beta subcomplex subunit 2 UCH PF00443.24 EIE91069.1 - 2.9e-78 262.6 0.0 6.5e-78 261.5 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EIE91069.1 - 1.3e-21 77.2 2.4 3.2e-13 49.7 0.1 2.5 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 EIE91069.1 - 3.8e-16 59.2 0.9 1.5e-15 57.3 0.6 2.1 1 0 0 1 1 1 1 DUSP domain DRMBL PF07522.9 EIE91070.1 - 5.2e-21 74.7 1.3 3.2e-18 65.7 0.9 2.6 1 1 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 EIE91070.1 - 7.9e-08 32.0 0.1 1.9e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EIE91070.1 - 0.015 14.9 0.1 0.032 13.8 0.0 1.5 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily RMMBL PF07521.7 EIE91070.1 - 0.11 12.2 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 RNA-metabolising metallo-beta-lactamase HLH PF00010.21 EIE91072.1 - 5.1e-09 35.7 7.0 5.1e-09 35.7 4.8 2.9 2 1 1 3 3 3 1 Helix-loop-helix DNA-binding domain Fib_alpha PF08702.5 EIE91072.1 - 0.046 13.8 5.0 0.078 13.0 3.4 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family POP1 PF06978.6 EIE91072.1 - 0.58 9.8 11.7 1.2 8.7 8.1 1.5 1 1 0 1 1 1 0 Ribonucleases P/MRP protein subunit POP1 ING PF12998.2 EIE91072.1 - 1.2 9.4 8.4 0.87 9.8 1.1 2.2 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding MerR-DNA-bind PF09278.6 EIE91072.1 - 2.1 8.7 6.6 15 6.0 0.5 2.3 2 0 0 2 2 2 0 MerR, DNA binding PPR_2 PF13041.1 EIE91073.1 - 5e-51 170.4 18.7 2.1e-10 40.3 0.4 13.2 11 3 3 14 14 14 9 PPR repeat family PPR_1 PF12854.2 EIE91073.1 - 4.7e-27 93.1 17.4 0.00019 20.8 0.0 12.4 14 0 0 14 14 14 8 PPR repeat PPR_3 PF13812.1 EIE91073.1 - 8.4e-27 91.1 9.1 0.0035 17.5 0.0 13.2 14 0 0 14 14 14 4 Pentatricopeptide repeat domain PPR PF01535.15 EIE91073.1 - 1.4e-21 74.9 18.8 0.0011 18.7 0.0 12.2 14 0 0 14 14 14 4 PPR repeat SPOB_a PF14689.1 EIE91073.1 - 0.15 11.6 4.0 0.95 9.0 0.0 3.8 5 0 0 5 5 5 0 Sensor_kinase_SpoOB-type, alpha-helical domain Clathrin PF00637.15 EIE91073.1 - 1.5 8.3 13.1 1.1 8.8 0.2 5.0 5 1 2 7 7 7 0 Region in Clathrin and VPS MMtag PF10159.4 EIE91074.1 - 1.6e-32 111.3 4.4 1.6e-32 111.3 3.0 4.0 2 1 1 3 3 3 1 Kinase phosphorylation protein PDCD2_C PF04194.8 EIE91074.1 - 1.7e-30 105.7 0.2 1.7e-30 105.7 0.2 3.9 3 1 0 3 3 3 1 Programmed cell death protein 2, C-terminal putative domain zf-MYND PF01753.13 EIE91074.1 - 1.9e-07 30.7 10.3 1.9e-07 30.7 7.1 2.8 3 0 0 3 3 3 1 MYND finger Ribosomal_S7e PF01251.13 EIE91076.1 - 4.3e-86 287.2 1.1 4.8e-86 287.1 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e DUF4174 PF13778.1 EIE91076.1 - 0.058 13.4 0.2 0.12 12.5 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4174) Sel1 PF08238.7 EIE91078.1 - 3.4e-136 440.7 68.1 1.9e-12 47.3 0.2 16.0 16 0 0 16 16 16 13 Sel1 repeat TPR_6 PF13174.1 EIE91078.1 - 0.0022 18.3 14.8 0.96 10.0 0.1 8.6 10 1 0 10 10 10 1 Tetratricopeptide repeat TPR_17 PF13431.1 EIE91078.1 - 0.012 15.7 17.5 24 5.4 0.2 9.3 7 2 3 10 10 10 0 Tetratricopeptide repeat TFIIB PF00382.14 EIE91078.1 - 0.31 10.8 2.1 25 4.7 0.0 4.8 6 0 0 6 6 6 0 Transcription factor TFIIB repeat Nuc_sug_transp PF04142.10 EIE91079.1 - 5.1e-95 317.2 7.3 6.7e-95 316.8 5.0 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter EmrE PF13536.1 EIE91079.1 - 8.9e-09 35.5 1.7 8.9e-09 35.5 1.2 2.5 2 1 0 2 2 2 1 Multidrug resistance efflux transporter EamA PF00892.15 EIE91079.1 - 1.5e-07 31.4 19.4 9.2e-07 28.9 1.3 2.4 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 EIE91079.1 - 0.00013 20.9 14.4 0.00034 19.6 8.9 2.0 1 1 1 2 2 2 2 UAA transporter family TPT PF03151.11 EIE91079.1 - 0.00017 21.3 1.5 0.00017 21.3 1.1 2.7 2 1 0 2 2 2 1 Triose-phosphate Transporter family UPF0546 PF10639.4 EIE91079.1 - 0.48 10.2 4.8 0.3 10.9 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0546 DUF202 PF02656.10 EIE91079.1 - 0.57 10.4 3.9 2.9 8.1 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF202) GTP_EFTU PF00009.22 EIE91080.1 - 1.8e-61 206.8 0.1 2.6e-61 206.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EIE91080.1 - 5.8e-36 122.6 0.0 1.5e-35 121.3 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 EIE91080.1 - 6.5e-23 80.4 0.0 1.6e-22 79.1 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EIE91080.1 - 5.5e-14 52.0 0.9 1.8e-13 50.3 0.1 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EIE91080.1 - 2.5e-13 49.6 0.0 5.6e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 EIE91080.1 - 0.00014 21.8 0.0 0.00032 20.6 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase HTH_29 PF13551.1 EIE91082.1 - 4.3e-08 33.2 0.3 1.1e-07 31.9 0.0 1.8 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.1 EIE91082.1 - 9e-08 32.8 0.0 3.6e-07 30.8 0.0 2.0 2 0 0 2 2 2 1 Homeodomain-like domain DDE_3 PF13358.1 EIE91082.1 - 0.00026 20.7 0.5 0.00097 18.8 0.4 2.0 1 1 0 1 1 1 1 DDE superfamily endonuclease PAX PF00292.13 EIE91082.1 - 0.0041 16.8 0.0 0.0071 16.0 0.0 1.3 1 0 0 1 1 1 1 'Paired box' domain HTH_Tnp_Tc3_2 PF01498.13 EIE91082.1 - 0.054 13.5 0.0 0.42 10.7 0.0 2.4 2 0 0 2 2 2 0 Transposase HTH_Tnp_1 PF01527.15 EIE91082.1 - 0.061 13.2 0.1 0.23 11.4 0.0 1.9 2 0 0 2 2 2 0 Transposase PBP1_TM PF14812.1 EIE91082.1 - 0.32 11.3 4.3 0.12 12.7 0.8 1.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DDE_3 PF13358.1 EIE91083.1 - 7.2e-10 38.7 0.1 8.7e-10 38.5 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Phage_DNA_bind PF02303.12 EIE91083.1 - 0.11 12.5 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Helix-destabilising protein Bac_DnaA PF00308.13 EIE91084.1 - 0.0018 17.9 0.3 0.003 17.2 0.2 1.4 1 1 0 1 1 1 1 Bacterial dnaA protein RhoGAP PF00620.22 EIE91085.1 - 2.4e-23 82.4 0.7 2.2e-14 53.3 0.3 2.5 1 1 1 2 2 2 2 RhoGAP domain Ribosomal_S6e PF01092.14 EIE91086.1 - 5.3e-63 210.3 0.3 5.3e-63 210.3 0.2 1.9 2 0 0 2 2 2 1 Ribosomal protein S6e Pkinase PF00069.20 EIE91087.1 - 2.4e-45 154.7 0.1 3.1e-45 154.3 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE91087.1 - 3e-23 82.2 0.0 3.6e-23 81.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE91087.1 - 0.00032 19.7 0.0 0.00041 19.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like POLO_box PF00659.13 EIE91088.1 - 4e-18 65.1 3.1 4.6e-09 36.1 0.6 3.1 2 1 1 3 3 3 2 POLO box duplicated region Tcp10_C PF07202.8 EIE91088.1 - 0.06 12.8 0.4 0.2 11.2 0.1 1.8 1 1 1 2 2 2 0 T-complex protein 10 C-terminus AA_permease PF00324.16 EIE91089.1 - 2.5e-125 418.5 55.2 2.8e-125 418.3 38.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EIE91089.1 - 1.1e-41 142.8 57.1 1.5e-41 142.3 39.6 1.2 1 0 0 1 1 1 1 Amino acid permease DUF1418 PF07214.7 EIE91089.1 - 5.8 6.6 8.4 1.2 8.7 1.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1418) Ras PF00071.17 EIE91090.1 - 2e-45 154.0 0.0 2.5e-45 153.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIE91090.1 - 1.8e-12 47.7 0.0 2.5e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIE91090.1 - 0.0043 16.3 0.0 0.0086 15.3 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family RVT_1 PF00078.22 EIE91091.1 - 5.9e-27 94.4 0.0 1.4e-26 93.2 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EIE91091.1 - 7.1e-18 64.3 2.2 2.7e-17 62.4 1.5 2.1 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EIE91091.1 - 1.2e-07 31.9 0.1 2.8e-07 30.7 0.1 1.7 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Lar_restr_allev PF14354.1 EIE91091.1 - 0.018 15.3 1.5 0.039 14.2 0.4 2.1 2 0 0 2 2 2 0 Restriction alleviation protein Lar Zn_Tnp_IS1595 PF12760.2 EIE91091.1 - 0.19 11.5 2.4 0.61 9.9 1.6 1.9 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.5 EIE91091.1 - 0.56 10.2 2.4 23 5.0 0.1 2.7 2 0 0 2 2 2 0 Zinc ribbon domain v110 PF01639.12 EIE91094.1 - 0.029 13.9 0.4 0.043 13.3 0.3 1.3 1 0 0 1 1 1 0 Viral family 110 RRM_1 PF00076.17 EIE91097.1 - 1.4e-05 24.5 0.0 2e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE91097.1 - 0.0097 15.8 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE91097.1 - 0.02 14.7 0.0 0.029 14.2 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EIE91097.1 - 0.05 13.4 0.0 0.074 12.8 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif SET PF00856.23 EIE91098.1 - 0.018 15.3 0.0 0.02 15.1 0.0 1.1 1 0 0 1 1 1 0 SET domain DDE_3 PF13358.1 EIE91100.1 - 7.7e-05 22.4 0.0 0.0001 22.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease SpoIIID PF12116.3 EIE91100.1 - 0.00049 19.9 0.1 0.001 18.9 0.0 1.6 1 0 0 1 1 1 1 Stage III sporulation protein D HTH_28 PF13518.1 EIE91100.1 - 0.0019 18.1 0.1 0.0085 16.0 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.1 EIE91100.1 - 0.0029 17.1 0.1 0.022 14.3 0.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain Sigma70_r4_2 PF08281.7 EIE91100.1 - 0.0035 16.7 0.0 0.0082 15.5 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_24 PF13412.1 EIE91100.1 - 0.012 14.9 0.1 0.029 13.7 0.1 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_38 PF13936.1 EIE91100.1 - 0.028 13.9 0.0 0.086 12.4 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain DivIC PF04977.10 EIE91100.1 - 0.042 13.3 2.2 0.084 12.3 1.5 1.5 1 0 0 1 1 1 0 Septum formation initiator HTH_17 PF12728.2 EIE91100.1 - 0.076 13.2 0.0 0.19 12.0 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_3 PF01381.17 EIE91100.1 - 0.11 12.3 0.5 0.25 11.2 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix TIR_2 PF13676.1 EIE91100.1 - 0.2 11.8 1.1 0.67 10.1 0.3 2.0 1 1 1 2 2 2 0 TIR domain DUF2360 PF10152.4 EIE91101.1 - 0.022 15.0 1.5 0.025 14.8 1.0 1.2 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) CASP_C PF08172.7 EIE91101.1 - 0.049 12.6 0.3 0.055 12.4 0.2 1.1 1 0 0 1 1 1 0 CASP C terminal DUF904 PF06005.7 EIE91101.1 - 0.057 13.7 2.2 0.083 13.1 1.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF904) EST1_DNA_bind PF10373.4 EIE91103.1 - 4.7e-26 91.6 1.8 7.8e-26 90.9 1.2 1.3 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.4 EIE91103.1 - 0.01 15.8 4.1 0.01 15.8 2.9 4.0 4 1 0 4 4 4 0 Telomerase activating protein Est1 Mpv17_PMP22 PF04117.7 EIE91103.1 - 0.11 12.0 0.1 0.39 10.3 0.0 1.9 2 0 0 2 2 2 0 Mpv17 / PMP22 family Ribosomal_L14e PF01929.12 EIE91104.1 - 4.6e-26 90.9 5.2 7.6e-26 90.2 3.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 EIE91104.1 - 0.0024 17.5 2.1 0.0027 17.3 0.4 1.8 2 0 0 2 2 2 1 KOW motif U6-snRNA_bdg PF10596.4 EIE91104.1 - 0.081 12.2 0.2 0.12 11.7 0.2 1.2 1 0 0 1 1 1 0 U6-snRNA interacting domain of PrP8 CTD_bind PF04818.8 EIE91105.1 - 0.00035 20.7 0.0 0.00091 19.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase II-binding domain. GTP_EFTU PF00009.22 EIE91105.1 - 0.017 14.5 0.1 0.035 13.5 0.1 1.5 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain DNA_RNApol_7kD PF03604.8 EIE91105.1 - 0.025 14.0 0.3 0.087 12.3 0.0 2.0 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zf-IS66 PF13005.2 EIE91105.1 - 0.037 13.9 0.1 0.79 9.7 0.0 2.7 2 0 0 2 2 2 0 zinc-finger binding domain of transposase IS66 zf-H2C2_2 PF13465.1 EIE91105.1 - 0.96 9.8 2.7 16 5.9 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger double domain Aminotran_4 PF01063.14 EIE91106.1 - 4.7e-06 26.2 0.0 5.6e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV zf-CCHC PF00098.18 EIE91108.1 - 0.00024 20.8 9.7 0.00047 19.9 1.3 2.4 2 0 0 2 2 2 2 Zinc knuckle Copper-fist PF00649.13 EIE91108.1 - 0.096 11.9 2.6 0.18 10.9 1.8 1.5 1 0 0 1 1 1 0 Copper fist DNA binding domain zf-CCHC_3 PF13917.1 EIE91108.1 - 0.17 11.6 9.7 0.072 12.8 1.6 2.3 1 1 1 2 2 2 0 Zinc knuckle GPI-anchored PF10342.4 EIE91109.1 - 2.1e-07 31.3 0.1 2.6e-07 30.9 0.1 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family GRAM PF02893.15 EIE91113.1 - 5.2e-19 67.5 0.1 9.6e-19 66.6 0.1 1.5 1 0 0 1 1 1 1 GRAM domain VitD-bind_III PF09164.5 EIE91113.1 - 0.037 13.6 0.1 0.083 12.5 0.1 1.5 1 0 0 1 1 1 0 Vitamin D binding protein, domain III Cyt-b5 PF00173.23 EIE91115.1 - 5.5e-23 80.5 0.3 8.5e-23 79.9 0.2 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Corona_6B_7B PF03262.8 EIE91115.1 - 0.089 12.0 0.1 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Coronavirus 6B/7B protein DUF1510 PF07423.6 EIE91116.1 - 0.0016 17.8 8.2 0.0022 17.3 5.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Sigma70_ner PF04546.8 EIE91116.1 - 6.6 6.2 11.4 9.1 5.8 7.9 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region PHD PF00628.24 EIE91117.1 - 2.1e-17 62.5 21.5 5.1e-10 38.8 7.2 2.9 2 1 1 3 3 3 2 PHD-finger zf-HC5HC2H PF13771.1 EIE91117.1 - 0.033 14.3 15.6 0.84 9.8 0.5 2.8 2 1 0 2 2 2 0 PHD-like zinc-binding domain DUF3895 PF13034.1 EIE91117.1 - 0.063 12.7 0.7 0.16 11.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3895) AP_endonuc_2 PF01261.19 EIE91117.1 - 0.15 11.3 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel C1_1 PF00130.17 EIE91117.1 - 0.16 11.7 18.8 0.045 13.4 1.3 3.1 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 EIE91117.1 - 8.3 6.2 20.0 0.48 10.1 1.2 3.0 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 zf-PHD-like PF15446.1 EIE91117.1 - 8.4 5.6 18.9 6.8 5.9 1.7 3.2 2 2 0 2 2 2 0 PHD/FYVE-zinc-finger like domain TRP PF06011.7 EIE91118.1 - 2.4e-11 42.8 0.2 2.8e-11 42.6 0.1 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel E1_DerP2_DerF2 PF02221.10 EIE91118.1 - 0.00073 19.7 0.0 0.0025 18.0 0.0 1.8 2 0 0 2 2 2 1 ML domain TRP PF06011.7 EIE91119.1 - 4.5e-18 65.0 1.6 4.6e-18 65.0 1.1 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel DUF1430 PF07242.6 EIE91119.1 - 1.5 8.9 11.3 0.3 11.1 3.1 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1430) Cation_ATPase_C PF00689.16 EIE91119.1 - 8.7 5.8 9.6 14 5.1 6.6 1.3 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus Ppx-GppA PF02541.11 EIE91120.1 - 1.5e-44 152.3 0.0 2.3e-44 151.6 0.0 1.2 1 0 0 1 1 1 1 Ppx/GppA phosphatase family DUF4099 PF13351.1 EIE91121.1 - 0.11 12.3 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4099) SNF2_N PF00176.18 EIE91127.1 - 1.5e-50 171.7 14.4 3.6e-27 94.9 0.0 3.5 2 1 1 3 3 3 2 SNF2 family N-terminal domain Helicase_C PF00271.26 EIE91127.1 - 1.1e-18 66.8 0.0 4.9e-17 61.5 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AT_hook PF02178.14 EIE91127.1 - 0.4 10.5 5.9 1.4 8.8 4.1 2.0 1 0 0 1 1 1 0 AT hook motif His_Phos_2 PF00328.17 EIE91128.1 - 2.3e-88 296.8 0.3 2.9e-88 296.5 0.2 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 EIE91128.1 - 6.2e-10 38.8 0.0 1.7e-09 37.4 0.0 1.7 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 EIE91128.1 - 0.0022 17.8 0.1 0.026 14.3 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp domain His_Phos_1 PF00300.17 EIE91128.1 - 0.036 14.1 0.0 0.089 12.8 0.0 1.7 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) DUF1162 PF06650.7 EIE91129.1 - 4.4e-65 219.6 13.9 2.8e-64 217.0 0.8 3.7 4 0 0 4 4 4 2 Protein of unknown function (DUF1162) Chorein_N PF12624.2 EIE91129.1 - 1.6e-39 134.1 2.5 6.4e-39 132.1 1.7 2.2 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 EIE91129.1 - 1e-06 28.8 0.0 8.5e-06 25.8 0.0 2.6 3 0 0 3 3 3 1 ATG C terminal domain Ribosomal_S3Ae PF01015.13 EIE91130.1 - 4.3e-66 221.9 5.6 5e-66 221.7 3.9 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Spt4 PF06093.8 EIE91130.1 - 0.081 12.8 0.3 0.73 9.7 0.0 2.3 2 0 0 2 2 2 0 Spt4/RpoE2 zinc finger DUF3571 PF12095.3 EIE91130.1 - 0.13 12.5 0.0 0.44 10.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3571) DUF496 PF04363.7 EIE91130.1 - 0.94 9.3 3.7 3.1 7.6 0.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF496) Ribosomal_S30 PF04758.9 EIE91131.1 - 3.9e-29 100.1 11.5 4.3e-29 100.0 8.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 IQ PF00612.22 EIE91132.1 - 2.8e-06 26.4 0.1 7.1e-06 25.2 0.1 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif Lzipper-MIP1 PF14389.1 EIE91132.1 - 0.00013 21.9 18.3 0.00033 20.6 3.2 3.7 1 1 2 3 3 3 1 Leucine-zipper of ternary complex factor MIP1 Viral_P18 PF04521.8 EIE91132.1 - 0.00056 19.3 1.6 0.00056 19.3 1.1 2.5 2 1 0 2 2 2 1 ssRNA positive strand viral 18kD cysteine rich protein DUF4391 PF14335.1 EIE91132.1 - 0.0015 17.9 4.3 0.0015 17.9 2.9 2.8 1 1 1 2 2 2 1 Domain of unknown function (DUF4391) Staphylokinase PF02821.11 EIE91132.1 - 0.017 14.9 5.3 0.2 11.4 0.1 2.8 2 0 0 2 2 2 0 Staphylokinase/Streptokinase family NPV_P10 PF05531.7 EIE91132.1 - 0.03 14.5 1.3 0.03 14.5 0.9 2.4 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein CENP-Q PF13094.1 EIE91132.1 - 0.31 11.0 25.8 3.7 7.5 7.9 2.6 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Hemerythrin PF01814.18 EIE91132.1 - 0.38 10.9 8.1 1.6 8.8 3.8 2.4 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain DUF4200 PF13863.1 EIE91132.1 - 3.4 7.6 29.2 0.23 11.4 13.9 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) V_ATPase_I PF01496.14 EIE91132.1 - 4.5 5.0 13.3 7.9 4.1 9.3 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cytochrom_B562 PF07361.6 EIE91132.1 - 4.6 7.7 13.3 2 8.8 1.8 3.6 2 1 2 4 4 4 0 Cytochrome b562 APG6 PF04111.7 EIE91132.1 - 7.8 5.4 23.0 28 3.5 15.8 2.0 1 1 0 1 1 1 0 Autophagy protein Apg6 PCI_Csn8 PF10075.4 EIE91133.1 - 6.8e-21 74.5 0.1 8.8e-21 74.1 0.1 1.1 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 EIE91133.1 - 0.0011 18.6 0.2 0.0014 18.2 0.1 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI PF01399.22 EIE91133.1 - 0.046 14.0 0.1 0.084 13.2 0.1 1.5 1 1 0 1 1 1 0 PCI domain Fasciclin PF02469.17 EIE91135.1 - 7.5e-44 148.8 10.2 1.8e-20 73.2 0.1 4.8 4 1 0 4 4 4 4 Fasciclin domain DUF4098 PF13345.1 EIE91135.1 - 0.0034 17.3 0.9 0.0034 17.3 0.6 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4098) Ubiquitin_2 PF14560.1 EIE91135.1 - 0.29 11.4 2.3 20 5.5 0.0 3.0 3 0 0 3 3 3 0 Ubiquitin-like domain zf-Nse PF11789.3 EIE91136.1 - 2.9e-18 65.1 0.4 5.2e-18 64.3 0.3 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4 PF00097.20 EIE91136.1 - 0.002 17.7 0.2 0.004 16.7 0.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-MIZ PF02891.15 EIE91136.1 - 0.011 15.1 0.9 0.027 13.9 0.6 1.7 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger zf-C3HC4_4 PF15227.1 EIE91136.1 - 0.013 15.4 0.3 0.028 14.3 0.1 1.6 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EIE91136.1 - 0.018 14.7 1.5 0.045 13.4 0.6 2.1 2 0 0 2 2 2 0 RING-type zinc-finger zf-Apc11 PF12861.2 EIE91136.1 - 0.022 14.5 0.3 0.076 12.8 0.2 1.9 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 EIE91136.1 - 0.054 13.5 0.2 0.17 12.0 0.1 2.0 2 1 0 2 2 2 0 RING-H2 zinc finger zf-RING_2 PF13639.1 EIE91136.1 - 0.083 12.7 0.5 0.18 11.6 0.4 1.6 1 0 0 1 1 1 0 Ring finger domain Ribosomal_S18 PF01084.15 EIE91137.1 - 1.3e-08 34.5 0.0 2.9e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S18 DUF3661 PF12400.3 EIE91141.1 - 1.3e-14 54.4 0.3 2.2e-14 53.6 0.2 1.4 1 0 0 1 1 1 1 Vaculolar membrane protein DUF1426 PF07234.6 EIE91141.1 - 0.0078 15.9 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1426) UCH PF00443.24 EIE91142.1 - 5.2e-10 38.8 1.1 8.6e-10 38.1 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.26 EIE91143.1 - 3.7e-08 32.9 0.3 1.1e-07 31.4 0.2 1.8 1 0 0 1 1 1 1 UBA/TS-N domain HBS1_N PF08938.5 EIE91143.1 - 0.004 17.2 0.3 0.29 11.2 0.0 2.6 2 1 0 2 2 2 1 HBS1 N-terminus Ribosomal_S17e PF00833.13 EIE91143.1 - 0.061 13.0 2.6 4.7 6.9 0.2 2.4 2 0 0 2 2 2 0 Ribosomal S17 KMP11 PF03037.11 EIE91147.1 - 0.031 14.8 0.0 0.042 14.4 0.0 1.4 1 1 0 1 1 1 0 Kinetoplastid membrane protein 11 Chromo PF00385.19 EIE91148.1 - 5.8e-11 41.8 0.6 1.3e-10 40.7 0.4 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain YcgR_2 PF12945.2 EIE91148.1 - 0.033 14.0 0.0 0.059 13.2 0.0 1.4 1 0 0 1 1 1 0 Flagellar protein YcgR S1_2 PF13509.1 EIE91148.1 - 0.1 12.5 0.0 0.27 11.1 0.0 1.7 1 0 0 1 1 1 0 S1 domain ALMS_motif PF15309.1 EIE91148.1 - 1.3 8.8 11.1 0.52 10.1 0.1 2.4 2 0 0 2 2 2 0 ALMS motif RVT_1 PF00078.22 EIE91149.1 - 5.5e-12 45.4 0.2 9.7e-12 44.6 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.12 EIE91151.1 - 0.00028 20.8 0.5 0.00081 19.4 0.1 1.9 2 0 0 2 2 2 1 Retrotransposon gag protein rve PF00665.21 EIE91152.1 - 2.7e-24 85.5 0.0 5.7e-24 84.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.5 EIE91152.1 - 0.00043 19.6 0.1 0.001 18.4 0.1 1.7 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger rve_3 PF13683.1 EIE91152.1 - 0.001 18.5 0.2 0.012 15.1 0.0 2.6 2 0 0 2 2 2 1 Integrase core domain DUF2246 PF10229.4 EIE91152.1 - 0.026 13.8 0.1 0.044 13.0 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2246) HTH_Tnp_Tc3_2 PF01498.13 EIE91153.1 - 1.1e-07 31.7 0.4 4.2e-07 29.9 0.1 2.1 2 0 0 2 2 2 1 Transposase RVT_1 PF00078.22 EIE91154.1 - 5.6e-10 38.9 0.1 3.1e-06 26.6 0.0 2.5 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) HTH_Tnp_Tc3_2 PF01498.13 EIE91155.1 - 0.001 19.0 0.3 0.002 18.1 0.2 1.4 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.1 EIE91155.1 - 0.012 15.3 0.0 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease RVT_1 PF00078.22 EIE91156.1 - 7.2e-30 103.9 0.2 1.6e-29 102.8 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease PF09668.5 EIE91156.1 - 4e-09 36.0 0.0 7.5e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 EIE91156.1 - 2.4e-07 31.1 0.0 6.1e-07 29.8 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 EIE91156.1 - 0.00031 20.6 2.0 0.00054 19.8 0.0 2.5 2 0 0 2 2 2 1 Retroviral aspartyl protease RVP_2 PF08284.6 EIE91156.1 - 0.00031 20.6 0.0 0.00072 19.5 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EIE91156.1 - 0.0059 16.4 0.1 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF3713 PF12506.3 EIE91157.1 - 0.00014 21.9 0.6 0.00028 20.9 0.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3713) TGS PF02824.16 EIE91157.1 - 0.0061 16.3 0.0 2.9 7.8 0.0 2.9 2 1 0 2 2 2 2 TGS domain rve PF00665.21 EIE91158.1 - 1.9e-22 79.6 0.0 4.7e-22 78.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE91158.1 - 1.5e-15 57.1 0.1 2.9e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.12 EIE91158.1 - 8.5e-09 35.3 0.1 2.4e-08 33.9 0.1 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein Chromo PF00385.19 EIE91158.1 - 4.4e-08 32.6 0.1 1e-07 31.5 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.1 EIE91158.1 - 5.3e-05 23.6 0.0 0.00012 22.4 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.5 EIE91158.1 - 0.00044 19.5 1.6 0.0015 17.8 1.1 2.0 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Asp_protease PF09668.5 EIE91158.1 - 0.0082 15.7 0.0 0.019 14.5 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EIE91158.1 - 0.023 14.4 0.0 0.058 13.2 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease UBN2 PF14223.1 EIE91158.1 - 0.14 11.9 0.0 0.37 10.5 0.0 1.8 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Transposase_21 PF02992.9 EIE91159.1 - 0.0015 17.6 0.0 0.0026 16.8 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DDE_3 PF13358.1 EIE91162.1 - 2.9e-18 66.0 0.5 9.4e-18 64.3 0.0 2.1 3 0 0 3 3 3 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE91162.1 - 4.6e-11 42.6 0.7 1.1e-10 41.4 0.5 1.7 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.1 EIE91162.1 - 0.045 13.8 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn helix Qn_am_d_aII PF14930.1 EIE91168.1 - 0.14 12.1 0.1 4.9 7.1 0.0 2.4 3 0 0 3 3 3 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain II DEC-1_N PF04625.8 EIE91168.1 - 0.17 10.5 9.7 0.3 9.7 6.7 1.5 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region PI31_Prot_N PF11566.3 EIE91169.1 - 0.037 13.6 0.2 0.045 13.3 0.1 1.1 1 0 0 1 1 1 0 PI31 proteasome regulator N-terminal OLF PF02191.11 EIE91170.1 - 0.03 13.5 1.3 0.032 13.4 0.9 1.0 1 0 0 1 1 1 0 Olfactomedin-like domain K_oxygenase PF13434.1 EIE91170.1 - 0.41 9.5 3.2 0.45 9.3 2.2 1.1 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) DUF3958 PF13125.1 EIE91170.1 - 0.8 9.6 6.8 0.28 11.1 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3958) DUF2058 PF09831.4 EIE91170.1 - 1.2 9.0 10.0 1.4 8.7 6.9 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) DUF1759 PF03564.10 EIE91171.1 - 0.0027 17.5 0.2 0.0046 16.7 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) RVT_1 PF00078.22 EIE91172.1 - 2.7e-11 43.2 0.0 5e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease PF09668.5 EIE91172.1 - 3.9e-10 39.3 0.0 8e-10 38.3 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 EIE91172.1 - 1e-08 35.5 0.0 2.4e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 EIE91172.1 - 5.1e-07 29.5 0.2 2.7e-06 27.2 0.0 2.4 2 0 0 2 2 2 1 Retroviral aspartyl protease RVP_2 PF08284.6 EIE91172.1 - 3.2e-06 27.1 0.0 6.7e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EIE91172.1 - 2.4e-05 24.0 0.1 5.1e-05 23.0 0.1 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease rve PF00665.21 EIE91173.1 - 3e-25 88.6 0.0 6.1e-25 87.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 EIE91173.1 - 0.00079 18.8 0.0 0.0022 17.4 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.5 EIE91173.1 - 0.00085 18.6 0.4 0.0024 17.2 0.3 1.8 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Transposase_21 PF02992.9 EIE91175.1 - 1.7e-21 76.3 0.0 3.2e-21 75.4 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 DUF1258 PF06869.7 EIE91175.1 - 0.0052 15.9 0.0 0.0088 15.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) FKBP_N PF01346.13 EIE91176.1 - 0.002 18.1 1.0 0.002 18.1 0.7 1.5 2 0 0 2 2 2 1 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Cornifin PF02389.10 EIE91176.1 - 0.0067 16.2 8.9 0.013 15.2 6.1 1.4 1 0 0 1 1 1 1 Cornifin (SPRR) family HTH_37 PF13744.1 EIE91176.1 - 0.14 11.9 5.8 11 5.9 3.6 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain RRF_GI PF12614.3 EIE91177.1 - 0.022 14.5 0.1 0.023 14.5 0.1 1.2 1 0 0 1 1 1 0 Ribosome recycling factor Transposase_21 PF02992.9 EIE91178.1 - 3.9e-22 78.4 0.1 8.2e-22 77.4 0.1 1.5 1 0 0 1 1 1 1 Transposase family tnp2 3HCDH_N PF02737.13 EIE91178.1 - 0.15 11.7 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RVT_1 PF00078.22 EIE91180.1 - 2.9e-23 82.3 0.6 6.3e-23 81.2 0.4 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP PF00077.15 EIE91180.1 - 8.7e-07 28.7 0.0 2e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EIE91180.1 - 7.8e-06 25.6 0.0 1.8e-05 24.4 0.0 1.7 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EIE91180.1 - 1.4e-05 25.5 0.0 2.5e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease rve PF00665.21 EIE91180.1 - 0.00042 20.4 0.0 0.001 19.1 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.6 EIE91180.1 - 0.0032 17.3 0.0 0.0067 16.3 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 EIE91180.1 - 0.051 13.1 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease RVT_1 PF00078.22 EIE91181.1 - 1e-21 77.2 0.1 1.8e-21 76.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.12 EIE91181.1 - 8.7e-08 32.1 0.2 2e-07 30.9 0.1 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein Asp_protease_2 PF13650.1 EIE91181.1 - 1e-07 32.3 0.1 3.7e-07 30.5 0.1 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EIE91181.1 - 7.9e-06 25.6 0.1 2.2e-05 24.1 0.1 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.18 EIE91181.1 - 0.00094 19.0 1.0 0.0018 18.1 0.7 1.5 1 0 0 1 1 1 1 Zinc knuckle Autophagy_N PF03986.8 EIE91181.1 - 0.025 14.3 0.3 0.054 13.2 0.2 1.5 1 0 0 1 1 1 0 Autophagocytosis associated protein (Atg3), N-terminal domain RVP PF00077.15 EIE91181.1 - 0.12 12.2 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease LAT PF15234.1 EIE91181.1 - 1.2 8.5 7.0 3 7.2 1.3 2.3 2 0 0 2 2 2 0 Linker for activation of T-cells rve PF00665.21 EIE91182.1 - 4.1e-21 75.2 0.0 5.8e-21 74.8 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain AcylCoA_dehyd_C PF12186.3 EIE91182.1 - 0.075 12.8 1.5 0.15 11.9 0.7 1.7 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase C terminal rve_3 PF13683.1 EIE91182.1 - 0.076 12.5 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain Chromo PF00385.19 EIE91183.1 - 1.6e-08 34.1 0.9 4.2e-08 32.7 0.6 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DDE_3 PF13358.1 EIE91184.1 - 8e-13 48.3 0.3 1e-12 48.0 0.2 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE91184.1 - 0.012 15.6 0.0 0.02 14.9 0.0 1.3 1 0 0 1 1 1 0 Integrase core domain rve PF00665.21 EIE91185.1 - 1.2e-19 70.5 0.0 7.7e-19 67.9 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 EIE91185.1 - 2.5e-11 43.3 1.3 9e-11 41.5 0.3 2.4 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP PF00077.15 EIE91185.1 - 0.0014 18.5 0.4 0.0054 16.6 0.1 2.3 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 EIE91185.1 - 0.022 15.2 0.1 0.091 13.2 0.0 2.2 2 0 0 2 2 2 0 Aspartyl protease Med15 PF09606.5 EIE91186.1 - 0.028 12.6 12.5 0.04 12.1 8.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal FlgM PF04316.8 EIE91186.1 - 2.2 8.2 5.1 13 5.8 2.9 2.3 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM Transposase_21 PF02992.9 EIE91187.1 - 6.8e-22 77.6 0.0 1.5e-21 76.5 0.0 1.5 1 0 0 1 1 1 1 Transposase family tnp2 DUF1258 PF06869.7 EIE91187.1 - 0.0026 16.8 0.0 0.0041 16.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) Chromo PF00385.19 EIE91189.1 - 3.6e-09 36.1 0.1 8.8e-09 34.9 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF1887 PF09002.6 EIE91189.1 - 0.043 12.2 0.0 3.1 6.0 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1887) DUF2870 PF11069.3 EIE91189.1 - 0.052 13.5 1.2 0.14 12.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) AKNA PF12443.3 EIE91189.1 - 0.063 13.2 0.1 0.21 11.6 0.1 1.9 1 0 0 1 1 1 0 AT-hook-containing transcription factor ATP-synt_D PF01813.12 EIE91189.1 - 0.41 10.1 3.8 0.25 10.8 0.9 1.8 2 0 0 2 2 2 0 ATP synthase subunit D HTH_23 PF13384.1 EIE91190.1 - 3.8e-05 23.1 0.0 4.8e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Homeodomain-like domain HTH_11 PF08279.7 EIE91190.1 - 6.3e-05 22.5 0.0 8.8e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 HTH domain HTH_IclR PF09339.5 EIE91190.1 - 6.5e-05 22.4 0.0 7.4e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_38 PF13936.1 EIE91190.1 - 0.00048 19.6 0.0 0.00055 19.4 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AsnC-type PF13404.1 EIE91190.1 - 0.0013 18.2 0.0 0.0018 17.7 0.0 1.3 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_7 PF02796.10 EIE91190.1 - 0.0014 18.4 0.0 0.002 17.9 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase Sigma70_r4_2 PF08281.7 EIE91190.1 - 0.0015 17.9 0.0 0.002 17.5 0.0 1.2 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_24 PF13412.1 EIE91190.1 - 0.003 16.9 0.0 0.0048 16.2 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding UPF0122 PF04297.9 EIE91190.1 - 0.0033 17.4 0.1 0.0037 17.2 0.0 1.1 1 0 0 1 1 1 1 Putative helix-turn-helix protein, YlxM / p13 like Sigma70_r4 PF04545.11 EIE91190.1 - 0.0036 16.5 0.0 0.0048 16.1 0.0 1.2 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_17 PF12728.2 EIE91190.1 - 0.0037 17.4 0.0 0.0042 17.2 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain Terminase_5 PF06056.7 EIE91190.1 - 0.008 15.7 0.0 0.0089 15.5 0.0 1.2 1 0 0 1 1 1 1 Putative ATPase subunit of terminase (gpP-like) GerE PF00196.14 EIE91190.1 - 0.0081 15.4 0.0 0.0095 15.2 0.0 1.2 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_36 PF13730.1 EIE91190.1 - 0.0099 15.9 0.0 0.014 15.4 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.1 EIE91190.1 - 0.01 15.9 0.0 0.011 15.9 0.0 1.1 1 0 0 1 1 1 0 Winged helix-turn helix HTH_Tnp_4 PF13613.1 EIE91190.1 - 0.013 15.0 0.0 0.017 14.6 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease Trp_repressor PF01371.14 EIE91190.1 - 0.014 15.3 0.0 0.015 15.2 0.0 1.1 1 0 0 1 1 1 0 Trp repressor protein HTH_6 PF01418.12 EIE91190.1 - 0.014 15.0 0.0 0.019 14.6 0.0 1.3 1 1 0 1 1 1 0 Helix-turn-helix domain, rpiR family HTH_28 PF13518.1 EIE91190.1 - 0.016 15.2 0.0 0.016 15.1 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Crp_2 PF13545.1 EIE91190.1 - 0.019 14.7 0.0 0.022 14.5 0.0 1.1 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain MarR_2 PF12802.2 EIE91190.1 - 0.02 14.5 0.0 0.029 14.0 0.0 1.3 1 1 0 1 1 1 0 MarR family HTH_30 PF13556.1 EIE91190.1 - 0.021 14.4 0.0 0.026 14.1 0.0 1.2 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain HTH_22 PF13309.1 EIE91190.1 - 0.025 14.3 0.0 0.034 13.9 0.0 1.2 1 0 0 1 1 1 0 HTH domain HTH_31 PF13560.1 EIE91190.1 - 0.028 14.6 0.0 0.032 14.4 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain DUF603 PF04645.7 EIE91190.1 - 0.055 13.4 0.0 0.058 13.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF603 HTH_40 PF14493.1 EIE91190.1 - 0.067 13.4 0.0 0.074 13.2 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_ECF PF07638.6 EIE91190.1 - 0.069 12.8 0.0 0.07 12.7 0.0 1.1 1 0 0 1 1 1 0 ECF sigma factor HTH_32 PF13565.1 EIE91190.1 - 0.071 13.9 0.4 0.13 13.1 0.0 1.6 1 1 1 2 2 2 0 Homeodomain-like domain HTH_20 PF12840.2 EIE91190.1 - 0.08 12.7 0.0 0.099 12.4 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_3 PF01381.17 EIE91190.1 - 0.088 12.6 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix HTH_Mga PF08280.6 EIE91190.1 - 0.088 12.5 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain TetR_N PF00440.18 EIE91190.1 - 0.098 12.3 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family DUF746 PF05344.6 EIE91190.1 - 0.12 11.9 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF746) DUF134 PF02001.11 EIE91190.1 - 0.14 12.0 0.0 0.16 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF134 DDE_3 PF13358.1 EIE91191.1 - 0.017 14.8 0.0 0.017 14.8 0.0 1.0 1 0 0 1 1 1 0 DDE superfamily endonuclease TFCD_C PF12612.3 EIE91192.1 - 0.01 15.2 0.1 0.017 14.5 0.1 1.4 1 0 0 1 1 1 0 Tubulin folding cofactor D C terminal DDE_3 PF13358.1 EIE91193.1 - 2.7e-28 98.5 0.0 6.1e-28 97.3 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 EIE91193.1 - 4e-10 39.8 0.2 1.7e-09 37.8 0.0 2.0 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.1 EIE91193.1 - 7.9e-08 32.9 0.4 2.4e-07 31.4 0.0 2.1 3 0 0 3 3 1 1 Homeodomain-like domain HTH_28 PF13518.1 EIE91193.1 - 2.3e-06 27.5 2.9 1e-05 25.4 0.1 2.9 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_23 PF13384.1 EIE91193.1 - 3.8e-05 23.1 2.4 0.00036 20.0 0.0 2.9 3 0 0 3 3 3 1 Homeodomain-like domain rve PF00665.21 EIE91193.1 - 0.0012 18.9 0.0 0.0038 17.3 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain HTH_17 PF12728.2 EIE91193.1 - 0.0046 17.1 0.2 0.92 9.8 0.1 2.8 2 0 0 2 2 2 1 Helix-turn-helix domain DDE_1 PF03184.14 EIE91193.1 - 0.0049 16.0 0.1 0.26 10.4 0.0 2.4 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_1 PF01527.15 EIE91193.1 - 0.0061 16.4 2.5 0.0072 16.2 0.3 2.1 2 0 0 2 2 2 1 Transposase Thioredoxin_2 PF13098.1 EIE91193.1 - 0.018 15.2 0.1 0.058 13.5 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin-like domain HTH_Tnp_ISL3 PF13542.1 EIE91193.1 - 0.033 13.3 0.1 0.069 12.3 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Terminase_5 PF06056.7 EIE91193.1 - 0.076 12.5 0.2 0.39 10.2 0.0 2.3 3 0 0 3 3 3 0 Putative ATPase subunit of terminase (gpP-like) PAS_3 PF08447.6 EIE91196.1 - 0.00033 20.6 0.1 0.00071 19.6 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS PF00989.19 EIE91196.1 - 0.075 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 PAS fold Epimerase PF01370.16 EIE91197.1 - 3.3e-69 232.9 0.0 4.4e-69 232.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EIE91197.1 - 1.4e-08 33.9 0.0 2.2e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EIE91197.1 - 0.00077 18.4 0.0 0.0014 17.6 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 EIE91197.1 - 0.0028 16.9 0.0 0.0047 16.2 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EIE91197.1 - 0.014 15.4 0.0 0.033 14.1 0.0 1.6 1 0 0 1 1 1 0 NADH(P)-binding Epimerase_Csub PF13950.1 EIE91197.1 - 0.017 15.0 0.0 0.033 14.1 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose 4-epimerase C-term subunit ASXH PF13919.1 EIE91198.1 - 1.5e-19 70.1 1.9 2.2e-19 69.6 1.3 1.2 1 0 0 1 1 1 1 Asx homology domain tRNA-synt_1b PF00579.20 EIE91199.1 - 1.8e-70 237.3 0.0 2.5e-70 236.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) DUF777 PF05606.6 EIE91202.1 - 0.12 11.5 0.5 0.56 9.3 0.0 1.9 1 1 1 2 2 2 0 Borrelia burgdorferi protein of unknown function (DUF777) Rsm22 PF09243.5 EIE91202.1 - 0.32 9.9 1.8 0.37 9.7 1.2 1.0 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 Ribosomal_S17e PF00833.13 EIE91203.1 - 1.5e-23 82.8 0.0 1.9e-23 82.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal S17 RNA_pol_Rpb5_C PF01191.14 EIE91203.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.4 1 1 0 1 1 1 0 RNA polymerase Rpb5, C-terminal domain DPM3 PF08285.6 EIE91204.1 - 3.5e-32 110.0 0.1 3.9e-32 109.9 0.1 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF1624 PF07786.7 EIE91204.1 - 0.072 12.4 0.2 0.081 12.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1624) DUF485 PF04341.7 EIE91204.1 - 0.13 11.9 0.8 0.15 11.7 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF485 FixP_N PF14715.1 EIE91204.1 - 0.35 10.2 8.7 2.5 7.5 0.8 2.2 2 0 0 2 2 2 0 N-terminal domain of cytochrome oxidase-cbb3, FixP ABC_membrane_2 PF06472.10 EIE91205.1 - 9.1e-102 339.9 8.1 1.3e-101 339.4 5.6 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EIE91205.1 - 2.7e-16 60.1 0.0 9.1e-16 58.4 0.0 1.9 3 0 0 3 3 1 1 ABC transporter RuvB_N PF05496.7 EIE91205.1 - 0.0054 15.8 0.0 0.013 14.5 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus SbmA_BacA PF05992.7 EIE91205.1 - 0.0062 15.7 1.7 0.0098 15.1 1.2 1.3 1 0 0 1 1 1 1 SbmA/BacA-like family AAA_19 PF13245.1 EIE91205.1 - 0.0075 15.9 0.0 0.019 14.7 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EIE91205.1 - 0.012 16.3 0.0 0.038 14.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EIE91205.1 - 0.014 15.5 0.0 0.032 14.4 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EIE91205.1 - 0.016 15.3 0.0 0.049 13.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EIE91205.1 - 0.019 14.9 0.0 0.036 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.1 EIE91205.1 - 0.023 15.0 2.4 0.57 10.4 0.0 2.7 3 0 0 3 3 3 0 AAA domain Mg_chelatase PF01078.16 EIE91205.1 - 0.034 13.3 0.0 0.067 12.3 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.7 EIE91205.1 - 0.048 13.3 0.0 0.091 12.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.1 EIE91205.1 - 0.076 12.5 0.0 0.22 11.0 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 EIE91205.1 - 0.12 12.1 0.0 0.26 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) FHA PF00498.21 EIE91206.1 - 1.7e-09 37.6 0.3 8.9e-09 35.3 0.2 2.1 1 1 0 1 1 1 1 FHA domain Pkinase PF00069.20 EIE91206.1 - 4.1e-05 22.8 0.1 8.3e-05 21.8 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE91206.1 - 0.05 12.6 0.0 0.079 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase YrpD PF15493.1 EIE91206.1 - 0.069 12.7 0.2 0.77 9.3 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function, YrpD SAF_2 PF13144.1 EIE91206.1 - 0.085 12.3 0.1 0.18 11.3 0.0 1.5 2 0 0 2 2 2 0 SAF-like AAA_18 PF13238.1 EIE91208.1 - 0.0026 18.0 0.0 0.0026 18.0 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 EIE91208.1 - 0.0029 18.4 0.0 0.005 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EIE91208.1 - 0.0064 16.6 1.8 0.02 15.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EIE91208.1 - 0.0077 15.9 0.0 0.017 14.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 EIE91208.1 - 0.0097 15.3 0.0 0.034 13.5 0.0 1.9 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_29 PF13555.1 EIE91208.1 - 0.013 14.9 0.0 0.037 13.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 EIE91208.1 - 0.013 15.4 2.1 0.029 14.3 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain DUF258 PF03193.11 EIE91208.1 - 0.038 13.1 0.0 0.038 13.1 0.0 1.9 3 0 0 3 3 3 0 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EIE91208.1 - 0.06 13.3 1.0 0.12 12.3 0.0 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase Miro PF08477.8 EIE91208.1 - 0.079 13.4 0.0 0.079 13.4 0.0 2.9 3 1 0 3 3 3 0 Miro-like protein ABC_tran PF00005.22 EIE91208.1 - 0.34 11.2 0.0 0.34 11.2 0.0 2.9 3 0 0 3 3 3 0 ABC transporter AAA_28 PF13521.1 EIE91208.1 - 1.6 8.6 0.0 1.6 8.6 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EIE91208.1 - 1.6 8.5 0.0 1.6 8.5 0.0 2.8 2 1 0 2 2 2 0 AAA domain TFIIA PF03153.8 EIE91208.1 - 3.4 7.4 30.5 5.5 6.7 21.1 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DAP3 PF10236.4 EIE91208.1 - 3.5 6.4 16.5 12 4.7 0.0 3.4 2 1 1 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 DDE_3 PF13358.1 EIE91213.1 - 7.5e-20 71.1 0.0 1e-12 48.0 0.0 2.1 2 0 0 2 2 2 2 DDE superfamily endonuclease WD40 PF00400.27 EIE91214.1 - 3.8e-23 80.4 0.9 0.00046 19.9 0.0 6.0 6 0 0 6 6 5 4 WD domain, G-beta repeat Methyltransf_31 PF13847.1 EIE91214.1 - 7.9e-13 48.2 0.1 1.6e-12 47.2 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EIE91214.1 - 9.5e-11 41.3 0.1 1.6e-10 40.5 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 EIE91214.1 - 9.5e-10 39.0 0.0 2.8e-09 37.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIE91214.1 - 3e-09 37.2 0.0 1.1e-08 35.4 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIE91214.1 - 4.8e-09 36.2 0.0 1.1e-08 35.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIE91214.1 - 2.2e-07 30.7 0.0 4.8e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 EIE91214.1 - 1.1e-06 27.5 0.1 2.1e-06 26.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.9 EIE91214.1 - 2e-06 27.2 0.2 4.3e-06 26.1 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 EIE91214.1 - 2e-05 24.9 0.0 6.5e-05 23.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIE91214.1 - 6e-05 23.3 0.0 0.00019 21.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EIE91214.1 - 0.00012 21.2 0.0 0.00021 20.4 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase LisH PF08513.6 EIE91214.1 - 0.00014 21.5 0.1 0.00042 19.9 0.0 1.9 2 0 0 2 2 1 1 LisH PRMT5 PF05185.11 EIE91214.1 - 0.00015 20.7 0.0 0.00024 20.1 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase FtsJ PF01728.14 EIE91214.1 - 0.0006 19.8 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_24 PF13578.1 EIE91214.1 - 0.0058 17.4 0.1 0.028 15.2 0.0 2.2 3 0 0 3 3 1 1 Methyltransferase domain UPF0020 PF01170.13 EIE91214.1 - 0.013 15.0 0.1 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_32 PF13679.1 EIE91214.1 - 0.024 14.3 0.0 0.058 13.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.4 EIE91214.1 - 0.027 13.9 0.2 0.048 13.1 0.1 1.3 1 0 0 1 1 1 0 Putative methyltransferase Cons_hypoth95 PF03602.10 EIE91214.1 - 0.036 13.4 0.0 2.7 7.3 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical protein 95 TehB PF03848.9 EIE91214.1 - 0.088 11.9 0.8 0.23 10.5 0.6 1.7 1 1 0 1 1 1 0 Tellurite resistance protein TehB 6PF2K PF01591.13 EIE91215.1 - 2.5e-79 265.4 0.1 3.8e-79 264.8 0.1 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EIE91215.1 - 3.7e-32 111.5 0.0 1.2e-31 110.0 0.0 1.9 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EIE91215.1 - 1.1e-11 44.7 0.0 2.5e-11 43.6 0.0 1.6 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.5 EIE91215.1 - 0.00055 19.2 0.1 0.00084 18.6 0.1 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.1 EIE91215.1 - 0.00059 20.6 1.2 0.0029 18.4 0.0 2.5 2 2 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EIE91215.1 - 0.0033 17.5 0.0 0.011 15.8 0.0 1.7 1 1 0 2 2 2 1 AAA domain SnoaL_2 PF12680.2 EIE91215.1 - 0.026 14.9 0.4 0.11 12.9 0.2 2.2 1 1 0 1 1 1 0 SnoaL-like domain AAA PF00004.24 EIE91215.1 - 0.047 13.8 0.0 0.19 11.9 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Val_tRNA-synt_C PF10458.4 EIE91215.1 - 0.073 13.1 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Valyl tRNA synthetase tRNA binding arm APS_kinase PF01583.15 EIE91215.1 - 0.096 12.3 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase DUF1098 PF06497.6 EIE91218.1 - 0.042 13.9 0.3 0.049 13.6 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1098) FlgN PF05130.7 EIE91218.1 - 0.095 12.9 0.1 0.11 12.8 0.0 1.1 1 0 0 1 1 1 0 FlgN protein ResIII PF04851.10 EIE91220.1 - 4.2e-21 75.6 0.0 1.6e-20 73.6 0.0 2.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EIE91220.1 - 2.2e-13 49.6 0.0 4.4e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 EIE91220.1 - 9.6e-09 34.9 0.0 1.7e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIE91220.1 - 1.9e-07 30.8 0.0 5.3e-07 29.4 0.0 1.8 1 1 0 1 1 1 1 Helicase conserved C-terminal domain AAA_34 PF13872.1 EIE91220.1 - 0.00069 18.4 0.0 0.0015 17.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 AAA_19 PF13245.1 EIE91220.1 - 0.081 12.6 0.1 0.2 11.4 0.1 1.6 1 0 0 1 1 1 0 Part of AAA domain eIF3_subunit PF08597.5 EIE91221.1 - 7.9e-37 127.1 31.2 7.9e-37 127.1 21.6 2.5 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit DUF3446 PF11928.3 EIE91221.1 - 0.05 13.8 8.0 0.12 12.6 5.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) Herpes_UL37_2 PF07413.6 EIE91221.1 - 0.16 10.7 2.8 0.086 11.6 0.1 1.8 2 0 0 2 2 2 0 Betaherpesvirus immediate-early glycoprotein UL37 GATA PF00320.22 EIE91222.1 - 9e-16 56.9 5.2 9e-16 56.9 3.6 2.3 2 0 0 2 2 2 1 GATA zinc finger M-inducer_phosp PF06617.8 EIE91222.1 - 4.2e-05 22.7 2.6 8.9e-05 21.6 1.8 1.5 1 0 0 1 1 1 1 M-phase inducer phosphatase PBP1_TM PF14812.1 EIE91222.1 - 0.026 14.8 5.4 0.026 14.8 3.7 1.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RRN7 PF11781.3 EIE91222.1 - 0.049 13.1 0.9 0.049 13.1 0.6 2.1 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 TF_Zn_Ribbon PF08271.7 EIE91222.1 - 0.054 12.8 1.8 0.19 11.0 1.2 2.0 1 0 0 1 1 1 0 TFIIB zinc-binding Pox_Ag35 PF03286.9 EIE91222.1 - 0.23 10.9 10.7 0.38 10.2 7.3 1.6 1 1 0 1 1 1 0 Pox virus Ag35 surface protein BSP_II PF05432.6 EIE91222.1 - 0.31 10.2 7.6 0.13 11.4 2.8 1.8 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) FAM60A PF15396.1 EIE91222.1 - 1.3 8.7 9.1 2.9 7.5 6.3 1.8 1 1 0 1 1 1 0 Protein Family FAM60A DUF755 PF05501.6 EIE91222.1 - 2.4 8.2 17.2 2.6 8.0 8.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Vpu PF00558.14 EIE91222.1 - 5.7 6.5 7.2 2.7 7.5 2.4 2.1 2 0 0 2 2 2 0 Vpu protein FAM176 PF14851.1 EIE91222.1 - 6.8 6.3 10.9 4.6 6.9 5.8 1.9 1 1 1 2 2 2 0 FAM176 family Cas_Csy4 PF09618.5 EIE91222.1 - 8.1 6.2 8.7 1.9 8.2 3.6 1.7 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csy4) Asn_synthase PF00733.16 EIE91223.1 - 6e-72 242.2 0.0 8.2e-72 241.7 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EIE91223.1 - 5.1e-41 139.3 0.0 9.4e-41 138.4 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EIE91223.1 - 2.3e-34 118.2 0.0 4.9e-34 117.1 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.3 EIE91223.1 - 1.2e-09 37.6 0.0 2.3e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein GATase_2 PF00310.16 EIE91223.1 - 3.5e-09 35.8 0.0 0.0049 15.6 0.0 3.2 1 1 2 3 3 3 3 Glutamine amidotransferases class-II NAD_synthase PF02540.12 EIE91223.1 - 0.03 13.2 0.0 0.079 11.8 0.0 1.7 2 0 0 2 2 2 0 NAD synthase DUF755 PF05501.6 EIE91224.1 - 0.58 10.2 8.8 0.83 9.7 6.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) DWNN PF08783.6 EIE91224.1 - 1.2 9.1 4.7 2.2 8.2 3.1 1.5 1 1 0 1 1 1 0 DWNN domain DUF2215 PF10225.4 EIE91224.1 - 1.9 7.8 4.3 2.1 7.7 3.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Methyltransf_11 PF08241.7 EIE91225.1 - 9.8e-16 58.0 0.0 2.1e-15 56.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIE91225.1 - 4.7e-14 52.4 0.0 7e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIE91225.1 - 5.3e-12 45.5 0.0 2.3e-11 43.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIE91225.1 - 2.4e-07 31.3 0.0 2.9e-06 27.8 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIE91225.1 - 9.6e-06 25.8 0.0 2e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EIE91225.1 - 4.9e-05 22.4 0.2 0.0015 17.6 0.0 2.4 2 1 0 2 2 2 1 Putative methyltransferase Methyltransf_12 PF08242.7 EIE91225.1 - 6.4e-05 23.3 0.0 0.00018 21.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIE91225.1 - 0.00035 19.7 0.0 0.001 18.2 0.0 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EIE91225.1 - 0.0077 16.2 0.0 0.018 15.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EIE91225.1 - 0.0081 15.5 0.0 0.022 14.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 EIE91225.1 - 0.011 14.8 0.0 0.02 14.0 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_8 PF05148.10 EIE91225.1 - 0.031 13.9 0.0 0.055 13.0 0.0 1.5 1 1 0 1 1 1 0 Hypothetical methyltransferase CMAS PF02353.15 EIE91225.1 - 0.031 13.3 0.7 0.75 8.8 0.0 2.5 2 1 0 2 2 2 0 Mycolic acid cyclopropane synthetase Pkinase PF00069.20 EIE91226.1 - 2.8e-53 180.7 0.0 3.4e-53 180.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE91226.1 - 1.4e-37 129.2 0.0 1.6e-37 128.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE91226.1 - 4.2e-06 25.9 0.0 6.2e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EIE91226.1 - 0.0067 15.2 0.0 0.0096 14.7 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Kinesin PF00225.18 EIE91227.1 - 5.3e-88 294.9 0.7 1.5e-87 293.4 0.0 2.2 2 0 0 2 2 2 1 Kinesin motor domain DUF2730 PF10805.3 EIE91227.1 - 0.0016 18.1 2.0 0.0016 18.1 1.4 4.1 4 1 0 4 4 4 1 Protein of unknown function (DUF2730) CotH PF08757.6 EIE91228.1 - 9.6e-36 123.6 8.6 1.8e-35 122.7 6.0 1.4 1 0 0 1 1 1 1 CotH protein C1_1 PF00130.17 EIE91230.1 - 3.3e-09 36.3 17.3 1.1e-05 25.0 4.0 2.6 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) UNC-79 PF14776.1 EIE91230.1 - 1.9e-05 23.2 0.1 0.0002 19.8 0.0 2.2 2 0 0 2 2 2 1 Cation-channel complex subunit UNC-79 Myb_DNA-binding PF00249.26 EIE91230.1 - 0.12 12.3 0.1 0.36 10.9 0.1 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain C1_3 PF07649.7 EIE91230.1 - 0.37 10.8 22.1 0.21 11.6 5.9 2.6 2 0 0 2 2 2 0 C1-like domain Nucleos_tra2_C PF07662.8 EIE91231.1 - 3.3e-67 226.0 12.3 7.3e-67 224.8 8.6 1.6 1 0 0 1 1 1 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 EIE91231.1 - 5.4e-24 84.3 3.9 5.4e-24 84.3 2.7 3.3 4 1 0 4 4 4 1 Na+ dependent nucleoside transporter N-terminus Pkinase PF00069.20 EIE91233.1 - 5.7e-60 202.6 0.0 6.8e-60 202.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE91233.1 - 1.5e-19 70.0 0.0 2.7e-19 69.2 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE91233.1 - 0.00011 21.2 0.0 0.0036 16.3 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Choline_kinase PF01633.15 EIE91233.1 - 0.0058 16.2 0.0 0.0092 15.5 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 EIE91233.1 - 0.016 14.9 0.0 0.053 13.2 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family GDA1_CD39 PF01150.12 EIE91234.1 - 1.7e-84 283.8 0.0 2e-84 283.6 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.11 EIE91234.1 - 9.6e-05 21.7 0.0 0.00014 21.1 0.0 1.2 1 0 0 1 1 1 1 Ppx/GppA phosphatase family MIP PF00230.15 EIE91236.1 - 3.3e-52 177.2 8.4 4.1e-52 176.9 5.8 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF3925 PF13063.1 EIE91236.1 - 0.088 12.8 1.6 0.26 11.3 1.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3925) Myb_DNA-binding PF00249.26 EIE91237.1 - 2.1e-08 34.0 0.0 5.6e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EIE91237.1 - 0.00012 22.0 0.1 0.00029 20.8 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain PT PF04886.7 EIE91237.1 - 0.0021 17.3 18.7 0.0021 17.3 13.0 2.5 1 1 0 1 1 1 1 PT repeat DUF4355 PF14265.1 EIE91237.1 - 0.01 15.8 21.9 0.01 15.8 15.2 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4355) PQ-loop PF04193.9 EIE91238.1 - 5.1e-21 73.9 6.8 7.3e-16 57.4 1.1 2.6 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.11 EIE91238.1 - 0.0068 16.2 1.3 0.0068 16.2 0.9 2.5 2 1 1 3 3 3 1 Sugar efflux transporter for intercellular exchange DUF912 PF06024.7 EIE91238.1 - 0.11 12.5 0.3 4.2 7.4 0.0 2.8 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) ER_lumen_recept PF00810.13 EIE91238.1 - 0.31 11.5 6.7 0.13 12.7 2.7 2.0 1 1 1 2 2 2 0 ER lumen protein retaining receptor MARVEL PF01284.18 EIE91238.1 - 0.37 10.6 9.8 1.9 8.3 1.3 2.6 1 1 1 2 2 2 0 Membrane-associating domain RhoGAP PF00620.22 EIE91242.1 - 4.4e-27 94.5 0.0 1.7e-26 92.6 0.0 2.0 2 0 0 2 2 2 1 RhoGAP domain MyTH4 PF00784.12 EIE91242.1 - 2.2e-13 50.1 3.5 1.2e-11 44.4 0.8 2.9 2 1 0 2 2 2 1 MyTH4 domain WW PF00397.21 EIE91242.1 - 0.00023 20.9 10.6 0.14 12.0 0.1 2.4 2 0 0 2 2 2 2 WW domain F-box-like PF12937.2 EIE91243.1 - 5.8e-07 29.1 1.1 3.3e-06 26.7 0.1 2.6 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 EIE91243.1 - 5.8e-07 28.9 0.3 1.4e-05 24.6 0.0 2.9 2 0 0 2 2 2 1 F-box domain F-box-like_2 PF13013.1 EIE91243.1 - 0.023 14.3 3.5 0.054 13.2 0.1 2.9 3 0 0 3 3 3 0 F-box-like domain LRR_4 PF12799.2 EIE91243.1 - 0.091 12.4 5.3 7.7 6.2 0.2 4.1 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EIE91243.1 - 7.8 6.9 6.8 50 4.4 0.1 4.1 4 0 0 4 4 4 0 Leucine Rich repeat Hydrolase_like2 PF13246.1 EIE91246.1 - 8.5e-20 70.5 0.1 2.4e-19 69.0 0.0 1.8 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase PF00702.21 EIE91246.1 - 2e-15 57.8 0.6 3.9e-15 56.8 0.3 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EIE91246.1 - 6.4e-07 29.7 0.0 1.1e-06 28.9 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EIE91246.1 - 0.0057 16.2 1.2 0.31 10.5 0.1 2.4 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EIE91246.1 - 0.022 14.9 0.0 0.28 11.3 0.0 2.5 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EIE91246.1 - 0.027 14.3 0.0 0.94 9.4 0.0 2.4 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EIE91247.1 - 4e-48 163.4 2.7 8.7e-48 162.3 1.9 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_N PF00690.21 EIE91247.1 - 2.5e-16 58.9 0.0 6e-16 57.6 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus DUF1622 PF07784.6 EIE91247.1 - 0.0023 17.5 0.1 0.033 13.8 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1622) CUE PF02845.11 EIE91249.1 - 2.6e-08 33.1 0.1 5.3e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 CUE domain GFA PF04828.9 EIE91250.1 - 2.2e-15 56.3 0.3 2.2e-15 56.3 0.2 1.6 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme RNA_POL_M_15KD PF02150.11 EIE91250.1 - 0.061 13.0 0.0 0.061 13.0 0.0 2.7 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit DUF2296 PF10058.4 EIE91250.1 - 0.36 10.6 3.4 7.4 6.4 0.7 2.3 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) Serum_albumin PF00273.15 EIE91251.1 - 0.0041 16.5 4.1 0.011 15.2 2.9 1.7 1 0 0 1 1 1 1 Serum albumin family Zn_clus PF00172.13 EIE91251.1 - 0.02 14.7 3.0 0.049 13.5 2.1 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4203 PF13886.1 EIE91252.1 - 3e-07 30.1 0.1 3.3e-07 29.9 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) DUF4203 PF13886.1 EIE91253.1 - 0.00038 19.9 11.8 0.00047 19.6 8.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) DUF872 PF05915.7 EIE91253.1 - 0.042 13.7 0.3 0.042 13.7 0.2 1.8 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF872) DUF3353 PF11833.3 EIE91254.1 - 0.022 14.2 0.5 0.03 13.7 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3353) Tim17 PF02466.14 EIE91254.1 - 0.066 13.2 0.1 0.17 11.9 0.0 1.6 1 1 1 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family Ank_2 PF12796.2 EIE91255.1 - 6.2e-26 90.5 0.0 4.1e-12 46.2 0.0 2.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EIE91255.1 - 2.2e-25 87.1 2.0 6.5e-08 32.0 0.0 6.0 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.1 EIE91255.1 - 9.1e-22 76.6 1.2 4.3e-09 36.3 0.0 4.7 1 1 4 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 EIE91255.1 - 3.6e-18 65.5 0.2 2.5e-10 40.5 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIE91255.1 - 3.6e-16 57.6 0.2 8.3e-05 22.4 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeat BAP PF06639.6 EIE91255.1 - 0.15 11.8 0.0 3.9 7.2 0.0 2.5 2 0 0 2 2 2 0 Basal layer antifungal peptide (BAP) GATA PF00320.22 EIE91256.1 - 1.4e-15 56.3 4.2 2.7e-15 55.4 2.9 1.5 1 0 0 1 1 1 1 GATA zinc finger COMPASS-Shg1 PF05205.7 EIE91256.1 - 0.089 13.0 1.5 0.15 12.3 1.1 1.3 1 0 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component shg1 ABC2_membrane PF01061.19 EIE91257.1 - 8.8e-84 279.8 74.2 2e-45 154.5 17.8 3.8 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.22 EIE91257.1 - 3.4e-36 124.5 0.0 4.5e-20 72.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EIE91257.1 - 2.8e-25 87.9 0.6 9.5e-19 66.9 0.0 3.8 4 1 2 6 6 4 2 CDR ABC transporter ABC2_membrane_3 PF12698.2 EIE91257.1 - 2.9e-11 42.9 48.3 4e-08 32.6 7.7 2.8 2 1 1 3 3 3 2 ABC-2 family transporter protein ABC_trans_N PF14510.1 EIE91257.1 - 1.2e-10 41.3 0.0 2.5e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_21 PF13304.1 EIE91257.1 - 1.7e-05 24.9 0.0 0.13 12.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EIE91257.1 - 7.1e-05 22.0 0.0 0.0025 17.0 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 EIE91257.1 - 0.00014 21.3 0.0 0.0046 16.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EIE91257.1 - 0.0008 19.5 1.1 0.11 12.6 0.0 3.5 4 1 0 4 4 3 1 AAA domain AAA_29 PF13555.1 EIE91257.1 - 0.0018 17.7 0.4 0.0076 15.7 0.1 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain UPF0079 PF02367.12 EIE91257.1 - 0.0021 17.7 0.9 0.96 9.0 0.1 2.4 2 0 0 2 2 2 2 Uncharacterised P-loop hydrolase UPF0079 AAA_33 PF13671.1 EIE91257.1 - 0.0037 17.1 0.9 0.76 9.6 0.0 3.2 4 0 0 4 4 2 1 AAA domain cobW PF02492.14 EIE91257.1 - 0.01 15.3 0.0 0.12 11.8 0.0 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.7 EIE91257.1 - 0.02 13.9 0.5 0.53 9.3 0.0 2.5 3 0 0 3 3 2 0 Zeta toxin AAA_17 PF13207.1 EIE91257.1 - 0.033 15.0 0.0 0.53 11.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EIE91257.1 - 0.035 13.8 0.7 2.3 8.0 0.1 2.5 2 0 0 2 2 2 0 Part of AAA domain Arch_ATPase PF01637.13 EIE91257.1 - 0.047 13.3 0.0 3.3 7.3 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase AAA_16 PF13191.1 EIE91257.1 - 0.052 13.5 0.1 0.68 9.8 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.1 EIE91257.1 - 0.085 12.8 0.1 0.28 11.1 0.1 1.9 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 EIE91257.1 - 0.088 12.7 0.0 0.54 10.2 0.0 2.2 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 EIE91257.1 - 0.11 12.7 0.0 0.7 10.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain TBD PF12845.2 EIE91257.1 - 0.21 11.1 0.0 0.51 9.9 0.0 1.6 1 0 0 1 1 1 0 TBD domain Miro PF08477.8 EIE91257.1 - 0.21 12.0 0.0 7.6 7.0 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein AAA PF00004.24 EIE91257.1 - 0.22 11.7 0.0 33 4.6 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EIE91257.1 - 0.3 10.7 0.4 3 7.4 0.1 2.3 2 0 0 2 2 2 0 NACHT domain FtsK_SpoIIIE PF01580.13 EIE91257.1 - 0.32 10.4 0.4 29 4.0 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_23 PF13476.1 EIE91257.1 - 0.83 9.9 0.0 0.83 9.9 0.0 1.8 2 0 0 2 2 1 0 AAA domain Oxidored_molyb PF00174.14 EIE91258.1 - 7.2e-23 80.8 0.0 9.1e-23 80.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 EIE91258.1 - 0.00084 18.9 0.0 0.0016 18.0 0.0 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain DUF4293 PF14126.1 EIE91259.1 - 0.96 9.3 7.8 1.3 8.9 5.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) Pox_D5 PF03288.11 EIE91260.1 - 0.058 13.6 0.4 0.071 13.3 0.3 1.3 1 0 0 1 1 1 0 Poxvirus D5 protein-like Ribosomal_L2_C PF03947.13 EIE91261.1 - 2.2e-47 160.0 3.2 2.9e-47 159.7 0.9 2.0 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EIE91261.1 - 1.1e-26 92.6 0.2 1.8e-26 91.8 0.1 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Cript PF10235.4 EIE91262.1 - 1.7e-06 28.2 1.7 4.9e-06 26.8 1.2 1.7 1 1 0 1 1 1 1 Microtubule-associated protein CRIPT Stanniocalcin PF03298.8 EIE91263.1 - 0.0013 17.7 0.1 0.0025 16.8 0.1 1.4 1 0 0 1 1 1 1 Stanniocalcin family DUF4298 PF14131.1 EIE91263.1 - 0.067 13.0 3.1 0.16 11.8 0.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4298) Glyco_transf_20 PF00982.16 EIE91264.1 - 2.4e-18 65.9 0.3 3.4e-18 65.4 0.2 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 AMP-binding PF00501.23 EIE91264.1 - 0.009 14.4 0.0 0.0099 14.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme RRM_1 PF00076.17 EIE91265.1 - 2.4e-09 36.7 0.9 7e-09 35.1 0.1 2.2 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE91265.1 - 1.2e-08 34.8 0.1 3.3e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) UPF0047 PF01894.12 EIE91266.1 - 1.2e-42 144.4 0.0 1.4e-42 144.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 PEPCK_ATP PF01293.15 EIE91267.1 - 3.3e-158 527.0 0.0 3.8e-158 526.8 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_16 PF13191.1 EIE91267.1 - 0.0075 16.2 0.0 0.032 14.2 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 EIE91267.1 - 0.11 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EIE91267.1 - 0.12 11.8 0.1 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EIE91267.1 - 0.13 13.0 0.0 0.32 11.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain Gti1_Pac2 PF09729.4 EIE91268.1 - 1.9e-47 161.2 3.5 8e-39 133.1 0.3 2.1 1 1 1 2 2 2 2 Gti1/Pac2 family AMP-binding PF00501.23 EIE91269.1 - 2.5e-91 306.1 0.1 3.4e-91 305.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme MPC PF03650.8 EIE91269.1 - 2.4e-39 133.9 0.1 6e-39 132.6 0.1 1.6 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) Acetyltransf_1 PF00583.19 EIE91270.1 - 2.2e-16 59.6 0.0 3.7e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EIE91270.1 - 3.2e-08 33.6 0.0 4.4e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EIE91270.1 - 2.4e-07 30.8 0.0 3.1e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EIE91270.1 - 3.4e-07 30.5 0.0 4.2e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EIE91270.1 - 5.9e-05 22.7 0.0 0.00011 21.8 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 EIE91270.1 - 0.0022 17.8 0.0 0.0058 16.4 0.0 1.8 1 1 1 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.1 EIE91270.1 - 0.053 13.4 0.0 0.091 12.7 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EIE91270.1 - 0.1 12.4 0.0 0.51 10.2 0.0 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain ZapA PF05164.8 EIE91271.1 - 0.071 13.0 0.7 0.15 12.0 0.5 1.6 1 1 0 1 1 1 0 Cell division protein ZapA NAAA-beta PF15508.1 EIE91271.1 - 0.077 13.3 0.5 0.83 10.0 0.0 2.1 1 1 1 2 2 2 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase DUF4600 PF15372.1 EIE91271.1 - 0.1 12.8 2.9 0.11 12.7 0.7 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4600) DUF3759 PF12585.3 EIE91272.1 - 2.6e-36 123.4 8.0 2.9e-36 123.2 5.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) SRP40_C PF05022.7 EIE91272.1 - 0.016 15.6 0.1 0.026 14.9 0.1 1.4 1 0 0 1 1 1 0 SRP40, C-terminal domain GnRH PF00446.12 EIE91273.1 - 9.5 6.4 6.2 0.98 9.5 0.7 2.0 2 0 0 2 2 2 0 Gonadotropin-releasing hormone zf-ribbon_3 PF13248.1 EIE91274.1 - 0.015 14.5 0.6 0.046 12.9 0.1 2.0 2 0 0 2 2 2 0 zinc-ribbon domain DUF1936 PF09151.5 EIE91274.1 - 0.069 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1936) GFA PF04828.9 EIE91274.1 - 0.099 12.5 1.0 1 9.3 0.1 2.3 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zinc_ribbon_2 PF13240.1 EIE91274.1 - 0.33 10.4 0.1 0.33 10.4 0.1 2.0 3 0 0 3 3 3 0 zinc-ribbon domain Fungal_trans PF04082.13 EIE91275.1 - 2.1e-31 108.7 0.8 2.1e-31 108.7 0.5 2.3 2 1 1 3 3 3 1 Fungal specific transcription factor domain Med3 PF11593.3 EIE91275.1 - 0.13 11.4 8.1 0.19 10.9 5.6 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal ChAPs PF09295.5 EIE91276.1 - 1.8e-113 379.3 0.2 1.7e-111 372.7 0.0 2.2 2 0 0 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.1 EIE91276.1 - 0.00058 20.1 0.1 0.019 15.3 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EIE91276.1 - 0.084 12.8 6.5 1.4 9.0 0.5 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Sugar_tr PF00083.19 EIE91277.1 - 4e-47 160.8 21.3 5e-47 160.4 14.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIE91277.1 - 8.5e-25 87.2 43.3 2.7e-21 75.7 20.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3357 PF11837.3 EIE91277.1 - 0.17 11.7 0.1 1.7 8.5 0.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) FUSC PF04632.7 EIE91277.1 - 0.21 10.0 0.0 0.21 10.0 0.0 2.6 3 0 0 3 3 3 0 Fusaric acid resistance protein family DUF2721 PF11026.3 EIE91277.1 - 2.2 7.9 7.7 2.7 7.6 1.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) AAA_11 PF13086.1 EIE91278.1 - 4.8e-13 49.2 0.0 1.1e-05 25.1 0.0 2.4 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.1 EIE91278.1 - 1.9e-08 34.1 0.0 0.00049 19.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EIE91278.1 - 0.0093 15.6 0.0 0.021 14.5 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 EIE91278.1 - 0.015 15.4 0.0 0.087 12.9 0.0 2.4 2 1 0 2 2 2 0 AAA domain DEAD PF00270.24 EIE91278.1 - 0.1 12.0 0.0 0.47 9.9 0.0 2.1 1 1 0 1 1 1 0 DEAD/DEAH box helicase PhoH PF02562.11 EIE91278.1 - 0.13 11.4 0.0 0.51 9.5 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein Fork_head PF00250.13 EIE91279.1 - 3.8e-35 119.8 0.6 8.3e-35 118.7 0.4 1.6 1 0 0 1 1 1 1 Fork head domain DUF155 PF02582.9 EIE91280.1 - 3.7e-37 127.8 2.6 7e-23 81.4 0.0 2.6 2 1 1 3 3 3 2 Uncharacterised ACR, YagE family COG1723 TraV PF09676.5 EIE91280.1 - 0.063 13.9 9.4 0.68 10.6 0.6 3.1 3 1 0 3 3 3 0 Type IV conjugative transfer system lipoprotein (TraV) RasGEF PF00617.14 EIE91281.1 - 8.7e-28 97.3 12.1 9.3e-27 93.9 3.8 3.2 2 2 0 2 2 2 2 RasGEF domain RasGEF_N PF00618.15 EIE91281.1 - 3.1e-17 62.5 3.1 3.1e-17 62.5 2.1 2.6 4 0 0 4 4 4 1 RasGEF N-terminal motif Delta_lysin PF05372.6 EIE91281.1 - 0.062 12.6 0.2 0.15 11.4 0.1 1.7 1 0 0 1 1 1 0 Delta lysin family NRN1 PF15056.1 EIE91281.1 - 0.085 12.8 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Neuritin protein family zf-HC5HC2H_2 PF13832.1 EIE91282.1 - 7.7e-15 54.8 8.5 7.7e-15 54.8 5.9 2.5 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EIE91282.1 - 3.9e-11 42.9 18.7 5.2e-11 42.5 4.1 3.1 2 1 0 2 2 2 1 PHD-like zinc-binding domain PHD_2 PF13831.1 EIE91282.1 - 4.5e-10 38.6 8.8 1.4e-09 37.0 1.3 2.9 2 0 0 2 2 2 1 PHD-finger PHD PF00628.24 EIE91282.1 - 1e-09 37.8 21.6 2.9e-07 30.0 5.8 2.9 2 0 0 2 2 2 2 PHD-finger FANCL_C PF11793.3 EIE91282.1 - 0.017 15.0 21.6 0.17 11.8 6.6 3.2 2 1 1 3 3 3 0 FANCL C-terminal domain MCPsignal PF00015.16 EIE91282.1 - 0.071 12.6 0.2 0.11 11.9 0.1 1.2 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain zf-RING-like PF08746.6 EIE91282.1 - 0.3 11.1 22.9 0.33 10.9 4.7 3.1 3 0 0 3 3 3 0 RING-like domain CENP-B_dimeris PF09026.5 EIE91282.1 - 1.1 9.4 16.5 0.55 10.5 3.0 2.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain NAD_kinase PF01513.16 EIE91283.1 - 1.9e-55 187.6 0.0 2.7e-54 183.8 0.0 2.1 1 1 0 1 1 1 1 ATP-NAD kinase Ribosomal_L12 PF00542.14 EIE91284.1 - 7.5e-05 22.6 0.0 10 6.1 0.0 5.0 3 1 2 5 5 5 2 Ribosomal protein L7/L12 C-terminal domain zf-CCCH_2 PF14608.1 EIE91284.1 - 0.00064 19.6 8.5 0.001 18.9 5.9 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type HLH PF00010.21 EIE91284.1 - 0.0036 16.9 0.3 14 5.4 0.0 5.5 7 0 0 7 7 7 1 Helix-loop-helix DNA-binding domain Ras PF00071.17 EIE91285.1 - 2.6e-62 209.0 0.2 3.3e-62 208.6 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIE91285.1 - 3.6e-22 79.0 0.1 5.3e-22 78.5 0.1 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIE91285.1 - 3.5e-13 49.1 0.1 4.9e-13 48.7 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EIE91285.1 - 3.5e-07 30.1 0.1 5.8e-07 29.4 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EIE91285.1 - 4.5e-06 26.8 0.0 1.3e-05 25.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain GTP_EFTU PF00009.22 EIE91285.1 - 6.5e-05 22.4 0.1 0.00022 20.6 0.1 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EIE91285.1 - 8e-05 21.8 0.1 0.00012 21.3 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_14 PF13173.1 EIE91285.1 - 0.00067 19.5 0.1 0.0015 18.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.1 EIE91285.1 - 0.00076 18.6 0.0 0.00092 18.3 0.0 1.2 1 1 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.5 EIE91285.1 - 0.0013 18.0 0.0 0.002 17.3 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit DUF258 PF03193.11 EIE91285.1 - 0.0038 16.4 0.0 0.01 15.0 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_24 PF13479.1 EIE91285.1 - 0.007 15.9 0.2 0.02 14.5 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_32 PF13654.1 EIE91285.1 - 0.015 14.0 0.1 0.14 10.7 0.0 2.0 1 1 1 2 2 2 0 AAA domain PduV-EutP PF10662.4 EIE91285.1 - 0.02 14.4 0.0 0.047 13.1 0.0 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.13 EIE91285.1 - 0.031 13.5 0.1 0.12 11.7 0.0 1.8 2 0 0 2 2 2 0 Ferrous iron transport protein B ABC_tran PF00005.22 EIE91285.1 - 0.032 14.5 0.1 0.044 14.0 0.1 1.5 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 EIE91285.1 - 0.052 13.5 0.2 0.1 12.5 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.1 EIE91285.1 - 0.087 12.7 0.1 0.37 10.7 0.1 2.2 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EIE91285.1 - 0.092 13.0 0.0 0.25 11.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EIE91285.1 - 0.093 12.4 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.10 EIE91285.1 - 0.094 12.4 0.1 0.18 11.4 0.1 1.5 1 1 0 1 1 1 0 NTPase Myb_DNA-bind_6 PF13921.1 EIE91286.1 - 5.9e-36 122.3 1.7 4.2e-11 42.7 1.1 4.3 1 1 3 4 4 4 4 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EIE91286.1 - 3.3e-32 110.2 12.2 2e-10 40.5 0.8 5.3 5 0 0 5 5 5 3 Myb-like DNA-binding domain Myb_DNA-bind_2 PF08914.6 EIE91286.1 - 0.006 16.3 0.0 4.9 7.0 0.0 3.4 3 0 0 3 3 3 1 Rap1 Myb domain Rap1_C PF11626.3 EIE91286.1 - 0.01 15.6 3.4 0.86 9.5 0.1 2.9 2 1 1 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Nop16 PF09420.5 EIE91286.1 - 0.039 14.0 0.5 0.11 12.6 0.0 2.0 2 1 0 3 3 3 0 Ribosome biogenesis protein Nop16 Annexin PF00191.15 EIE91286.1 - 0.059 13.2 0.0 0.24 11.3 0.0 2.0 2 0 0 2 2 2 0 Annexin Myb_DNA-bind_5 PF13873.1 EIE91286.1 - 0.51 10.2 5.2 43 4.0 0.0 5.4 6 1 1 7 7 7 0 Myb/SANT-like DNA-binding domain Ras PF00071.17 EIE91287.1 - 2.4e-61 205.8 0.1 3.8e-61 205.1 0.0 1.3 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EIE91287.1 - 1.2e-17 64.5 0.0 2.7e-17 63.3 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EIE91287.1 - 3.7e-12 45.8 0.0 4.7e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EIE91287.1 - 2.1e-05 24.0 0.1 3.1e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EIE91287.1 - 0.035 13.2 0.0 0.049 12.7 0.0 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region bZIP_1 PF00170.16 EIE91288.1 - 2.7e-10 40.0 12.7 2.7e-10 40.0 8.8 2.1 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EIE91288.1 - 1.3e-06 28.0 11.1 1.3e-06 28.0 7.7 2.9 3 1 1 4 4 4 1 Basic region leucine zipper bZIP_Maf PF03131.12 EIE91288.1 - 0.00033 20.8 10.9 0.00033 20.8 7.6 2.6 3 0 0 3 3 3 1 bZIP Maf transcription factor DUF904 PF06005.7 EIE91288.1 - 0.0048 17.1 0.8 0.0048 17.1 0.5 3.3 4 0 0 4 4 4 1 Protein of unknown function (DUF904) Dendrin PF15498.1 EIE91288.1 - 0.058 11.9 0.3 0.084 11.3 0.2 1.1 1 0 0 1 1 1 0 Nephrin and CD2AP-binding protein, Dendrin DUF1640 PF07798.6 EIE91288.1 - 1.3 9.0 10.9 0.19 11.7 3.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) Peptidase_C2 PF00648.16 EIE91289.1 - 9e-34 116.8 0.0 1.7e-33 115.9 0.0 1.4 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.17 EIE91289.1 - 4.4e-09 36.1 0.0 1.2e-05 24.9 0.0 3.7 2 1 1 3 3 3 1 Calpain large subunit, domain III MIT PF04212.13 EIE91289.1 - 2.2e-08 33.8 1.5 2.2e-08 33.8 1.0 2.4 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain SNAP PF14938.1 EIE91289.1 - 0.0016 17.6 0.7 0.0025 17.0 0.5 1.3 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP GCV_H PF01597.14 EIE91290.1 - 4.3e-45 152.3 0.5 5e-45 152.1 0.3 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.17 EIE91290.1 - 0.00051 19.6 0.3 0.0012 18.4 0.3 1.6 2 0 0 2 2 2 1 Biotin-requiring enzyme RnfC_N PF13375.1 EIE91290.1 - 0.026 14.2 0.1 0.041 13.5 0.1 1.3 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain Pyr_redox_2 PF07992.9 EIE91291.1 - 9.4e-13 48.4 0.2 2.4e-11 43.8 0.2 3.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EIE91291.1 - 7.8e-05 22.8 0.1 0.15 12.1 0.0 2.7 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EIE91291.1 - 9.6e-05 22.2 0.0 0.35 10.6 0.0 2.7 3 0 0 3 3 3 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EIE91291.1 - 0.0083 15.0 0.0 0.11 11.3 0.0 2.1 1 1 1 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.22 EIE91291.1 - 0.014 15.8 0.0 0.073 13.4 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EIE91291.1 - 0.031 13.1 0.2 1.2 7.9 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Attachment_P66 PF11263.3 EIE91291.1 - 0.031 13.2 0.0 0.067 12.2 0.0 1.5 1 1 0 1 1 1 0 Borrelia burgdorferi attachment protein P66 HI0933_like PF03486.9 EIE91291.1 - 0.072 11.5 0.0 0.12 10.8 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_2 PF00890.19 EIE91291.1 - 0.1 11.3 0.3 0.21 10.3 0.2 1.5 1 1 0 1 1 1 0 FAD binding domain NAD_binding_8 PF13450.1 EIE91291.1 - 0.13 12.3 0.1 1.2 9.2 0.0 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EIE91291.1 - 0.17 10.8 0.0 0.51 9.3 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain C2 PF00168.25 EIE91292.1 - 6.2e-21 74.0 0.8 7.1e-10 38.6 0.2 2.6 2 0 0 2 2 2 2 C2 domain DnaJ PF00226.26 EIE91294.1 - 9.2e-18 63.7 0.1 1.3e-17 63.2 0.1 1.2 1 0 0 1 1 1 1 DnaJ domain DPM3 PF08285.6 EIE91294.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) NB PF04159.8 EIE91294.1 - 0.12 12.0 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 NB glycoprotein Nop PF01798.13 EIE91295.1 - 3e-60 201.8 0.4 6.8e-60 200.7 0.3 1.6 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EIE91295.1 - 9.8e-27 92.5 0.1 2e-26 91.5 0.1 1.6 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EIE91295.1 - 2.4e-22 78.8 1.4 2.4e-22 78.8 0.9 3.0 2 0 0 2 2 2 1 NOP5NT (NUC127) domain RNA_polI_A34 PF08208.6 EIE91295.1 - 0.0015 18.2 30.4 0.003 17.2 21.1 1.6 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 GAGA_bind PF06217.7 EIE91295.1 - 0.14 12.1 12.6 0.25 11.2 8.7 1.5 1 0 0 1 1 1 0 GAGA binding protein-like family RR_TM4-6 PF06459.7 EIE91295.1 - 0.43 10.4 18.9 0.91 9.3 13.1 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDHD PF02862.12 EIE91295.1 - 7.1 6.3 13.9 16 5.1 9.6 1.7 1 0 0 1 1 1 0 DDHD domain DUF221 PF02714.10 EIE91296.1 - 3e-23 82.1 2.6 4.5e-23 81.6 1.8 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF221 DUF4463 PF14703.1 EIE91296.1 - 1.8e-16 60.4 1.2 2.1e-15 57.0 0.9 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4463) EI24 PF07264.6 EIE91296.1 - 0.013 14.9 0.6 0.018 14.4 0.4 1.2 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) DUF1305 PF06996.6 EIE91296.1 - 0.13 11.2 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1305) FAM176 PF14851.1 EIE91297.1 - 0.0067 16.1 0.1 0.0067 16.1 0.1 2.3 2 1 0 2 2 2 1 FAM176 family TEX19 PF15553.1 EIE91297.1 - 2.1 8.2 5.2 0.72 9.7 0.4 2.4 2 1 1 3 3 3 0 Testis-expressed protein 19 HAD_2 PF13419.1 EIE91298.1 - 2.2e-19 70.3 0.0 2.7e-19 70.0 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EIE91298.1 - 2.6e-07 30.2 0.1 4.5e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Pyr_redox_2 PF07992.9 EIE91299.1 - 9.9e-46 156.1 0.2 2.4e-45 154.9 0.1 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EIE91299.1 - 2.1e-42 143.5 1.0 4.2e-41 139.4 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 EIE91299.1 - 2.2e-20 72.8 12.6 1.1e-18 67.4 0.7 3.6 5 0 0 5 5 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EIE91299.1 - 2.9e-14 52.9 0.4 4.5e-11 42.4 0.1 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EIE91299.1 - 4.5e-11 43.2 2.0 2.9e-06 27.5 0.4 2.7 1 1 2 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EIE91299.1 - 9.6e-11 41.1 8.1 6.4e-10 38.4 1.6 2.5 2 1 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.19 EIE91299.1 - 6.3e-10 38.4 15.3 5.3e-08 32.1 1.0 4.7 4 1 1 5 5 5 2 FAD binding domain Thi4 PF01946.12 EIE91299.1 - 3.9e-09 35.9 5.6 1.3e-07 30.9 0.2 2.6 1 1 1 2 2 2 2 Thi4 family NAD_binding_8 PF13450.1 EIE91299.1 - 1e-07 31.8 4.7 0.00016 21.6 0.2 2.9 3 0 0 3 3 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EIE91299.1 - 2.3e-07 30.1 7.1 0.021 13.8 0.3 3.3 3 0 0 3 3 3 3 FAD binding domain HI0933_like PF03486.9 EIE91299.1 - 2.9e-07 29.3 12.7 1.2e-05 24.0 0.5 4.1 4 0 0 4 4 4 2 HI0933-like protein DAO PF01266.19 EIE91299.1 - 2e-05 23.6 19.4 0.0011 17.9 0.7 4.1 2 2 1 4 4 4 3 FAD dependent oxidoreductase K_oxygenase PF13434.1 EIE91299.1 - 0.00029 19.8 0.1 0.14 11.0 0.0 2.6 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.16 EIE91299.1 - 0.00056 19.5 5.2 0.0055 16.2 0.2 3.2 2 1 1 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 EIE91299.1 - 0.0019 17.8 4.8 0.022 14.4 0.4 2.7 3 0 0 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 EIE91299.1 - 0.021 14.1 2.6 0.15 11.4 0.1 2.4 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.1 EIE91299.1 - 0.026 14.7 0.8 11 6.3 0.2 2.9 3 0 0 3 3 2 0 Putative NAD(P)-binding Lycopene_cycl PF05834.7 EIE91299.1 - 0.069 12.0 8.0 0.065 12.1 0.3 3.0 3 0 0 3 3 3 0 Lycopene cyclase protein His_Phos_1 PF00300.17 EIE91300.1 - 1.5e-23 83.6 0.0 2e-23 83.2 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) GHL1-3 PF11308.3 EIE91300.1 - 0.039 13.2 0.0 0.052 12.8 0.0 1.3 1 1 0 1 1 1 0 Glycosyl hydrolases related to GH101 family, GHL1-GHL3 Sec23_trunk PF04811.10 EIE91302.1 - 6.4e-77 258.2 0.0 9.1e-77 257.6 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EIE91302.1 - 2.3e-33 113.6 0.1 4.8e-33 112.6 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EIE91302.1 - 9.2e-32 109.4 0.8 1.9e-31 108.4 0.6 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EIE91302.1 - 6.3e-18 64.0 5.4 1.3e-17 63.0 3.7 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EIE91302.1 - 1e-13 50.7 0.0 4.3e-13 48.7 0.0 2.0 2 0 0 2 2 2 1 Gelsolin repeat MutS_V PF00488.16 EIE91304.1 - 4.3e-97 324.1 0.0 8.1e-97 323.2 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EIE91304.1 - 4.6e-24 85.3 6.7 7.8e-24 84.5 2.7 2.5 2 1 0 2 2 2 1 MutS domain III MutS_IV PF05190.13 EIE91304.1 - 6.6e-12 45.4 3.5 6.6e-12 45.4 2.5 2.2 2 0 0 2 2 2 1 MutS family domain IV MutS_I PF01624.15 EIE91304.1 - 3.1e-09 36.8 0.0 8.2e-09 35.4 0.0 1.8 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 EIE91304.1 - 0.00049 20.1 0.6 0.0015 18.6 0.0 2.1 2 0 0 2 2 2 1 MutS domain II DUF1213 PF06740.7 EIE91304.1 - 0.42 10.7 2.8 0.88 9.7 2.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1213) DUF883 PF05957.8 EIE91304.1 - 1.2 9.5 3.4 0.66 10.4 0.1 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Redoxin PF08534.5 EIE91306.1 - 7.8e-36 122.8 0.0 9.1e-36 122.5 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EIE91306.1 - 2.1e-13 50.0 0.0 2.6e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Cornichon PF03311.9 EIE91308.1 - 7e-44 149.0 2.0 7.9e-44 148.8 1.4 1.0 1 0 0 1 1 1 1 Cornichon protein PAP_assoc PF03828.14 EIE91310.1 - 4e-17 61.9 0.1 1.8e-16 59.8 0.0 2.0 2 0 0 2 2 2 1 Cid1 family poly A polymerase DUF500 PF04366.7 EIE91311.1 - 6.1e-41 138.7 0.2 1.1e-40 138.0 0.1 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF500) Pkinase PF00069.20 EIE91312.1 - 1.3e-59 201.4 0.4 1.8e-59 200.9 0.3 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE91312.1 - 8.9e-29 100.3 0.2 1.3e-28 99.8 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE91312.1 - 2.7e-06 26.5 0.0 4.4e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EIE91312.1 - 0.00032 19.8 0.3 0.00058 18.9 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIE91312.1 - 0.00035 20.3 0.0 0.0015 18.3 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EIE91312.1 - 0.00073 18.9 0.6 0.0016 17.8 0.3 1.5 1 1 0 1 1 1 1 PhoP regulatory network protein YrbL Pox_ser-thr_kin PF05445.6 EIE91312.1 - 0.0057 15.4 0.2 0.011 14.5 0.2 1.4 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase RIO1 PF01163.17 EIE91312.1 - 0.0094 15.3 0.3 0.025 13.9 0.2 1.7 1 0 0 1 1 1 1 RIO1 family PPR_2 PF13041.1 EIE91313.1 - 1.8e-41 139.8 3.5 2.4e-09 37.0 0.1 8.3 4 2 4 8 8 8 6 PPR repeat family PPR_3 PF13812.1 EIE91313.1 - 3.3e-24 83.0 9.4 0.0076 16.4 0.0 9.4 10 0 0 10 10 10 7 Pentatricopeptide repeat domain PPR PF01535.15 EIE91313.1 - 4.2e-22 76.5 2.1 0.0023 17.8 0.0 8.8 9 0 0 9 9 9 5 PPR repeat PPR_1 PF12854.2 EIE91313.1 - 2.7e-14 52.3 6.5 0.014 14.8 0.0 7.0 8 0 0 8 8 8 4 PPR repeat ATP13 PF12921.2 EIE91313.1 - 0.0032 16.8 1.0 1.9 7.8 0.1 3.6 2 1 1 3 3 3 1 Mitochondrial ATPase expression DUF3366 PF11846.3 EIE91313.1 - 0.025 14.4 1.0 0.83 9.4 0.0 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF3366) TPR_12 PF13424.1 EIE91313.1 - 0.03 14.2 1.4 0.94 9.4 0.1 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat RPM2 PF08579.6 EIE91313.1 - 0.034 14.2 9.4 5.1 7.2 0.1 5.3 2 1 4 6 6 6 0 Mitochondrial ribonuclease P subunit (RPM2) TPR_16 PF13432.1 EIE91313.1 - 0.035 14.8 0.1 0.2 12.4 0.0 2.3 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 EIE91313.1 - 0.042 14.1 0.9 0.37 11.1 0.1 2.9 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 EIE91313.1 - 0.077 13.4 0.4 14 6.4 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat CARD PF00619.16 EIE91313.1 - 0.086 12.6 4.0 0.26 11.1 0.0 3.8 5 0 0 5 5 5 0 Caspase recruitment domain TPR_14 PF13428.1 EIE91313.1 - 0.2 12.4 1.2 15 6.5 0.0 3.6 4 0 0 4 4 2 0 Tetratricopeptide repeat Mcp5_PH PF12814.2 EIE91314.1 - 7.4e-19 67.8 0.9 3.8e-18 65.5 0.6 2.3 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology ERM PF00769.14 EIE91314.1 - 0.16 11.4 65.0 0.069 12.6 28.3 4.6 4 0 0 4 4 4 0 Ezrin/radixin/moesin family NADH-u_ox-rdase PF10785.4 EIE91315.1 - 3.4e-31 107.3 0.7 4.8e-31 106.8 0.5 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.2 EIE91315.1 - 3.3e-19 68.3 0.1 4.9e-19 67.8 0.0 1.3 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit Spond_N PF06468.8 EIE91315.1 - 0.03 14.0 0.0 0.044 13.4 0.0 1.2 1 0 0 1 1 1 0 Spondin_N tRNA_SAD PF07973.9 EIE91316.1 - 3.4e-08 33.2 1.4 1e-07 31.7 1.0 1.9 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_2c PF01411.14 EIE91316.1 - 1.2e-06 27.1 0.9 1.1e-05 23.9 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class II (A) PocR PF10114.4 EIE91316.1 - 0.012 14.8 0.1 0.022 13.8 0.0 1.5 1 0 0 1 1 1 0 Sensory domain found in PocR HGTP_anticodon PF03129.15 EIE91318.1 - 9.1e-15 54.3 0.2 3.2e-14 52.6 0.2 1.9 2 0 0 2 2 2 1 Anticodon binding domain ATP-grasp_5 PF13549.1 EIE91318.1 - 0.096 11.8 0.0 0.26 10.4 0.0 1.7 2 0 0 2 2 2 0 ATP-grasp domain DUF423 PF04241.10 EIE91319.1 - 0.012 15.5 0.0 0.014 15.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF423) Coiled-coil_56 PF09813.4 EIE91319.1 - 0.024 14.5 0.0 0.03 14.3 0.0 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 56 DEAD_2 PF06733.10 EIE91320.1 - 1.4e-28 99.4 0.1 1.4e-28 99.4 0.1 1.9 2 0 0 2 2 2 1 DEAD_2 ResIII PF04851.10 EIE91320.1 - 0.39 10.5 10.7 11 5.7 7.2 2.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Colicin_immun PF09204.5 EIE91320.1 - 2 8.5 9.6 0.37 10.8 1.6 2.6 2 1 1 3 3 3 0 Bacterial self-protective colicin-like immunity Acetyltransf_1 PF00583.19 EIE91322.1 - 3.5e-11 42.9 0.1 5.3e-11 42.4 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EIE91322.1 - 3.6e-09 36.6 0.1 5.7e-09 36.0 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EIE91322.1 - 3.5e-06 26.8 0.0 1e-05 25.3 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EIE91322.1 - 5.6e-05 23.2 0.0 8.3e-05 22.6 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.1 EIE91322.1 - 0.0041 17.6 0.0 0.011 16.2 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Phenol_hyd_sub PF06099.6 EIE91322.1 - 0.011 15.5 0.0 1.4 8.7 0.0 3.0 3 0 0 3 3 3 0 Phenol hydroxylase subunit Pox_D5 PF03288.11 EIE91322.1 - 0.023 14.9 0.0 0.49 10.7 0.0 2.1 2 0 0 2 2 2 0 Poxvirus D5 protein-like FR47 PF08445.5 EIE91322.1 - 0.037 13.7 0.0 0.057 13.1 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein DDE_1 PF03184.14 EIE91323.1 - 1.4e-05 24.3 0.3 0.13 11.3 0.0 2.2 1 1 1 2 2 2 2 DDE superfamily endonuclease HA2 PF04408.18 EIE91325.1 - 1.1e-27 96.0 0.0 2.1e-27 95.0 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EIE91325.1 - 1.9e-20 72.8 0.0 4.2e-20 71.6 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EIE91325.1 - 2.3e-14 52.9 0.0 4.5e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EIE91325.1 - 2e-05 24.1 0.1 4.3e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase NADH_B2 PF14813.1 EIE91326.1 - 0.0025 17.4 0.6 0.0026 17.3 0.4 1.2 1 0 0 1 1 1 1 NADH dehydrogenase 1 beta subcomplex subunit 2 Ribosomal_L32e PF01655.13 EIE91327.1 - 2.3e-47 159.5 1.5 2.8e-47 159.3 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 Pro_isomerase PF00160.16 EIE91328.1 - 2.9e-15 56.8 0.0 4.1e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Histone PF00125.19 EIE91330.1 - 4.7e-22 77.8 0.0 6e-22 77.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EIE91330.1 - 0.00051 20.0 0.0 0.00073 19.5 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF1880 PF08976.6 EIE91330.1 - 0.098 12.7 0.1 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1880) LisH PF08513.6 EIE91330.1 - 0.16 11.8 0.9 2.1 8.2 0.0 2.7 3 0 0 3 3 3 0 LisH zf-Tim10_DDP PF02953.10 EIE91331.1 - 3.4e-24 83.8 0.8 4.3e-24 83.5 0.5 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF2408 PF10303.4 EIE91331.1 - 0.015 15.4 1.3 0.017 15.2 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) Nsp1_C PF05064.8 EIE91331.1 - 0.85 9.2 3.0 1.2 8.7 0.8 2.0 1 1 2 3 3 3 0 Nsp1-like C-terminal region Peptidase_S8 PF00082.17 EIE91333.1 - 3.8e-47 160.8 7.0 8.4e-47 159.6 4.8 1.5 1 0 0 1 1 1 1 Subtilase family DUF936 PF06075.7 EIE91333.1 - 0.85 8.4 27.3 1.1 8.0 18.9 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) DNA_pol_viral_N PF00242.12 EIE91333.1 - 1.5 7.7 28.2 2.3 7.1 19.6 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Endonuc-MspI PF09208.5 EIE91334.1 - 0.013 14.5 0.1 0.026 13.6 0.1 1.4 1 0 0 1 1 1 0 Restriction endonuclease MspI SpoU_methylase PF00588.14 EIE91335.1 - 1.8e-17 63.5 0.0 1.5e-16 60.5 0.0 2.3 2 1 0 2 2 2 1 SpoU rRNA Methylase family COG2 PF06148.6 EIE91336.1 - 0.002 17.9 4.2 0.035 13.9 0.1 2.3 1 1 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Nup54 PF13874.1 EIE91336.1 - 0.0035 17.0 3.6 0.0036 16.9 1.3 1.8 1 1 1 2 2 2 1 Nucleoporin complex subunit 54 Fib_alpha PF08702.5 EIE91336.1 - 0.01 15.9 5.7 0.01 15.9 4.0 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Laminin_II PF06009.7 EIE91336.1 - 0.015 15.0 0.4 0.015 15.0 0.2 2.2 1 1 1 2 2 2 0 Laminin Domain II Chloroplast_duf PF14476.1 EIE91336.1 - 0.024 13.4 0.2 0.04 12.7 0.0 1.5 1 1 0 1 1 1 0 Petal formation-expressed RmuC PF02646.11 EIE91336.1 - 0.031 13.1 3.1 0.079 11.7 0.1 2.1 2 0 0 2 2 2 0 RmuC family Baculo_PEP_C PF04513.7 EIE91336.1 - 0.05 13.4 0.8 0.14 11.9 0.1 1.9 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Mistic PF11458.3 EIE91336.1 - 0.063 13.6 3.1 0.35 11.2 0.3 2.4 2 1 0 2 2 2 0 Membrane-integrating protein Mistic DUF1192 PF06698.6 EIE91336.1 - 0.097 12.4 0.2 0.27 11.0 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) NPV_P10 PF05531.7 EIE91336.1 - 0.1 12.8 1.2 0.26 11.5 0.8 2.0 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein PLAC9 PF15205.1 EIE91336.1 - 0.14 12.4 0.1 2.6 8.3 0.0 2.5 2 1 0 2 2 2 0 Placenta-specific protein 9 DUF1664 PF07889.7 EIE91336.1 - 0.16 11.7 3.1 0.35 10.6 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Pepsin-I3 PF06394.8 EIE91336.1 - 0.42 10.2 2.5 0.97 9.1 0.6 2.2 2 0 0 2 2 2 0 Pepsin inhibitor-3-like repeated domain MutS_III PF05192.13 EIE91336.1 - 0.56 9.9 6.4 1.1 8.9 4.5 1.5 1 1 0 1 1 1 0 MutS domain III MbeD_MobD PF04899.7 EIE91336.1 - 0.69 9.8 4.8 0.6 10.0 0.4 2.7 2 1 1 3 3 3 0 MbeD/MobD like DUF972 PF06156.8 EIE91336.1 - 0.74 10.1 8.4 27 5.1 5.7 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF972) IncA PF04156.9 EIE91336.1 - 1.1 8.8 14.2 3.4 7.2 9.5 1.9 1 1 0 1 1 1 0 IncA protein DUF1474 PF07342.6 EIE91336.1 - 1.2 9.3 8.1 0.23 11.6 1.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1474) Fzo_mitofusin PF04799.8 EIE91336.1 - 6.2 6.1 9.5 0.65 9.3 0.8 2.0 1 1 1 2 2 2 0 fzo-like conserved region zf-RING_2 PF13639.1 EIE91337.1 - 1.2e-05 25.0 5.7 1.2e-05 25.0 3.9 2.3 2 0 0 2 2 2 1 Ring finger domain SWIM PF04434.12 EIE91337.1 - 0.0001 21.7 0.6 0.00022 20.6 0.4 1.6 1 0 0 1 1 1 1 SWIM zinc finger C1_1 PF00130.17 EIE91337.1 - 0.0013 18.3 2.5 0.0013 18.3 1.7 2.2 1 1 1 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_5 PF14634.1 EIE91337.1 - 0.006 16.2 7.4 0.006 16.2 5.1 2.2 2 0 0 2 2 2 1 zinc-RING finger domain RINGv PF12906.2 EIE91337.1 - 0.024 14.6 7.4 0.056 13.4 5.1 1.6 1 0 0 1 1 1 0 RING-variant domain PSD1 PF07587.6 EIE91337.1 - 0.031 13.6 0.3 0.047 13.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1553) PHD_2 PF13831.1 EIE91337.1 - 0.053 12.8 4.2 0.093 12.0 2.9 1.4 1 0 0 1 1 1 0 PHD-finger zf-Apc11 PF12861.2 EIE91337.1 - 0.053 13.3 2.9 0.16 11.8 2.0 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DZR PF12773.2 EIE91337.1 - 0.072 12.9 3.1 0.22 11.3 2.1 1.9 1 0 0 1 1 1 0 Double zinc ribbon zf-TFIIB PF13453.1 EIE91337.1 - 0.095 11.9 1.1 0.22 10.7 0.8 1.6 1 0 0 1 1 1 0 Transcription factor zinc-finger PHD PF00628.24 EIE91337.1 - 0.16 11.7 8.8 0.35 10.5 6.1 1.6 1 0 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.1 EIE91337.1 - 0.23 11.2 7.2 0.76 9.5 5.0 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 FANCL_C PF11793.3 EIE91337.1 - 0.76 9.7 7.3 2.1 8.3 5.1 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_2 PF13923.1 EIE91337.1 - 2.3 8.2 15.0 0.036 14.1 5.1 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Sterol_MT_C PF08498.5 EIE91338.1 - 1.4e-26 92.1 1.1 2.3e-26 91.4 0.8 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 EIE91338.1 - 5.1e-23 81.3 0.1 1.4e-22 79.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIE91338.1 - 1.1e-18 67.2 0.0 2.1e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIE91338.1 - 8.4e-14 51.5 0.0 1.9e-13 50.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIE91338.1 - 4.4e-13 49.4 0.0 1.6e-12 47.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIE91338.1 - 6e-12 45.1 0.0 1e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EIE91338.1 - 2.3e-11 44.0 0.0 6e-11 42.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EIE91338.1 - 3.1e-11 42.8 0.3 4.8e-11 42.2 0.2 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 EIE91338.1 - 1.3e-09 38.6 0.0 3.3e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIE91338.1 - 1.7e-08 34.4 0.0 4e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EIE91338.1 - 1e-05 24.9 0.0 2.5e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.5 EIE91338.1 - 0.0088 15.6 0.1 0.017 14.6 0.0 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PCMT PF01135.14 EIE91338.1 - 0.017 14.6 0.1 0.12 11.8 0.1 2.0 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.7 EIE91338.1 - 0.017 14.4 0.0 0.043 13.1 0.0 1.7 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.1 EIE91338.1 - 0.044 13.4 0.3 0.094 12.4 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain PrmA PF06325.8 EIE91338.1 - 0.076 12.1 0.0 0.18 10.8 0.0 1.7 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) STE PF02200.11 EIE91339.1 - 4.6e-44 149.0 0.3 1.6e-43 147.3 0.1 1.9 2 0 0 2 2 2 1 STE like transcription factor zf-C2H2_4 PF13894.1 EIE91339.1 - 1.4e-10 40.7 8.0 8.9e-05 22.5 0.2 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EIE91339.1 - 5.3e-09 35.9 20.5 5.7e-06 26.3 0.6 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIE91339.1 - 2.1e-08 34.0 15.1 4.2e-08 33.0 1.7 3.7 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 EIE91339.1 - 0.00027 20.7 0.5 0.00027 20.7 0.3 2.3 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EIE91339.1 - 0.071 13.2 9.1 0.08 13.1 0.2 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Ank_4 PF13637.1 EIE91340.1 - 4.6e-29 100.2 3.3 2.9e-12 46.7 0.2 3.8 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 EIE91340.1 - 3e-28 97.9 4.7 4.7e-12 46.0 0.7 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EIE91340.1 - 6.4e-23 79.3 5.4 0.00018 21.1 0.0 5.8 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 EIE91340.1 - 2.6e-21 75.1 2.7 2.1e-06 27.8 0.0 4.1 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIE91340.1 - 6e-19 66.2 6.1 0.0011 18.9 0.0 6.0 6 0 0 6 6 6 4 Ankyrin repeat Shigella_OspC PF06128.6 EIE91340.1 - 0.0063 16.0 0.0 0.0097 15.4 0.0 1.3 1 0 0 1 1 1 1 Shigella flexneri OspC protein DUF1620 PF07774.8 EIE91341.1 - 8.8e-67 224.5 0.5 1.6e-66 223.7 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 EIE91341.1 - 9.1e-05 22.0 0.1 0.0088 15.5 0.1 2.7 2 1 0 2 2 2 2 PQQ-like domain PQQ PF01011.16 EIE91341.1 - 0.0096 15.4 0.1 3.3 7.4 0.0 3.1 2 0 0 2 2 2 2 PQQ enzyme repeat DUF2428 PF10350.4 EIE91343.1 - 2e-67 226.9 0.0 8.3e-67 224.8 0.0 2.2 2 0 0 2 2 2 1 Putative death-receptor fusion protein (DUF2428) Ran_BP1 PF00638.13 EIE91343.1 - 7.3e-18 64.7 0.5 1.8e-17 63.4 0.3 1.7 1 0 0 1 1 1 1 RanBP1 domain HEAT PF02985.17 EIE91343.1 - 7e-05 22.5 5.0 7.6 6.9 0.0 6.7 8 0 0 8 8 8 2 HEAT repeat Ribonuc_red_lgC PF02867.10 EIE91344.1 - 4.8e-219 728.4 0.0 7.6e-219 727.7 0.0 1.3 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 EIE91344.1 - 7.4e-24 83.3 0.0 1.6e-23 82.3 0.0 1.6 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 EIE91344.1 - 1.3e-16 60.7 0.3 5.7e-16 58.7 0.1 2.3 2 0 0 2 2 2 1 ATP cone domain DUF367 PF04034.8 EIE91345.1 - 1.3e-49 167.0 0.0 2.1e-49 166.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 EIE91345.1 - 4.8e-12 45.2 1.4 8.1e-12 44.5 1.0 1.4 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI CDC73 PF05179.9 EIE91346.1 - 5.9e-60 202.9 6.5 8.6e-60 202.3 4.5 1.3 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family Cu-oxidase_3 PF07732.10 EIE91348.1 - 7.8e-13 48.1 0.5 2.3e-12 46.6 0.4 1.8 1 1 0 1 1 1 1 Multicopper oxidase Gb3_synth PF04572.7 EIE91348.1 - 0.049 13.3 0.6 0.21 11.2 0.4 2.1 1 1 0 1 1 1 0 Alpha 1,4-glycosyltransferase conserved region DUF2847 PF11009.3 EIE91348.1 - 0.13 11.8 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) HMG_box PF00505.14 EIE91349.1 - 2e-16 59.9 1.5 4.6e-16 58.8 1.1 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EIE91349.1 - 3.9e-12 46.3 1.1 8.6e-12 45.2 0.8 1.6 1 0 0 1 1 1 1 HMG-box domain SAM_2 PF07647.12 EIE91349.1 - 0.00036 20.3 0.1 0.00071 19.3 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EIE91349.1 - 0.00046 20.2 0.4 0.00082 19.5 0.3 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) NCD1 PF04904.8 EIE91349.1 - 0.0014 18.3 0.8 0.003 17.2 0.2 1.8 2 0 0 2 2 2 1 NAB conserved region 1 (NCD1) Baculo_RING PF05883.6 EIE91349.1 - 0.027 14.3 0.7 9 6.1 0.0 2.5 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain DUF1963 PF09234.5 EIE91349.1 - 0.031 14.5 2.2 0.054 13.7 1.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1963) AT_hook PF02178.14 EIE91349.1 - 0.22 11.2 1.4 0.5 10.2 1.0 1.6 1 0 0 1 1 1 0 AT hook motif Rpr2 PF04032.11 EIE91350.1 - 9.4e-19 67.0 3.2 9.4e-19 67.0 2.2 1.9 2 0 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain FUR PF01475.14 EIE91350.1 - 0.0064 16.4 1.9 0.038 13.9 0.1 2.4 1 1 1 2 2 2 1 Ferric uptake regulator family NMD3 PF04981.8 EIE91350.1 - 0.015 14.3 2.0 0.022 13.9 1.4 1.3 1 0 0 1 1 1 0 NMD3 family Cbl_N3 PF02762.9 EIE91350.1 - 0.029 13.9 0.0 0.07 12.7 0.0 1.6 1 1 0 1 1 1 0 CBL proto-oncogene N-terminus, SH2-like domain Nudix_N_2 PF14803.1 EIE91350.1 - 0.12 12.0 0.5 0.67 9.6 0.0 2.1 2 0 0 2 2 2 0 Nudix N-terminal FdhD-NarQ PF02634.10 EIE91350.1 - 0.14 11.5 1.2 0.21 11.0 0.6 1.4 1 1 0 1 1 1 0 FdhD/NarQ family Rsm1 PF08600.5 EIE91350.1 - 0.32 10.8 1.5 0.32 10.8 0.2 1.7 2 0 0 2 2 2 0 Rsm1-like BLVR PF06375.6 EIE91350.1 - 0.69 9.7 7.4 3.5 7.4 2.2 2.2 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) eIF_4EBP PF05456.6 EIE91350.1 - 1.7 8.3 5.8 1.3 8.6 1.8 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) MGC-24 PF05283.6 EIE91350.1 - 3.9 7.2 9.4 6.1 6.5 6.4 1.4 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) IPP-2 PF04979.9 EIE91351.1 - 1.1e-11 45.0 12.1 2.3e-11 44.0 8.4 1.5 1 1 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) DUF4247 PF14042.1 EIE91351.1 - 0.079 12.9 0.3 0.18 11.8 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4247) Nucleo_P87 PF07267.6 EIE91351.1 - 0.093 11.4 5.1 0.1 11.2 3.5 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 NhaB PF06450.7 EIE91351.1 - 0.15 10.6 0.1 0.19 10.3 0.1 1.0 1 0 0 1 1 1 0 Bacterial Na+/H+ antiporter B (NhaB) Bud13 PF09736.4 EIE91351.1 - 0.35 11.1 10.9 1.8 8.8 0.1 2.1 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex Di19_C PF14571.1 EIE91351.1 - 1.5 9.1 5.4 0.5 10.6 1.5 1.7 2 0 0 2 2 2 0 Stress-induced protein Di19, C-terminal WD40 PF00400.27 EIE91352.1 - 1.4e-30 103.9 6.3 1.1e-07 31.4 0.0 5.6 6 0 0 6 6 6 4 WD domain, G-beta repeat Ecl1 PF12855.2 EIE91353.1 - 9.9e-09 34.3 0.4 9.9e-09 34.3 0.3 1.7 2 0 0 2 2 2 1 Life-span regulatory factor zf-MYND PF01753.13 EIE91353.1 - 0.0019 18.0 0.4 0.0041 16.9 0.3 1.6 1 0 0 1 1 1 1 MYND finger SR-25 PF10500.4 EIE91353.1 - 7.2 6.0 8.5 8.8 5.7 5.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ca_hom_mod PF14798.1 EIE91354.1 - 0.007 15.3 1.0 0.012 14.5 0.6 1.5 1 1 0 1 1 1 1 Calcium homeostasis modulator DUF2207 PF09972.4 EIE91354.1 - 0.23 9.9 9.5 0.013 14.1 2.2 1.9 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) DUF4131 PF13567.1 EIE91354.1 - 0.28 10.5 0.1 0.28 10.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) TRAPP PF04051.11 EIE91354.1 - 0.44 10.0 0.1 0.44 10.0 0.1 2.4 3 0 0 3 3 3 0 Transport protein particle (TRAPP) component DUF4181 PF13789.1 EIE91354.1 - 8.3 6.3 12.0 1 9.2 4.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4181) TRAPP PF04051.11 EIE91355.1 - 9.3e-16 57.7 0.0 1.1e-15 57.5 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Carboxyl_trans PF01039.17 EIE91356.1 - 7.5e-154 512.7 0.0 9.3e-154 512.4 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 EIE91356.1 - 0.0073 15.5 0.0 1.5 7.9 0.0 2.8 3 0 0 3 3 3 2 Malonate decarboxylase gamma subunit (MdcE) ECH PF00378.15 EIE91356.1 - 1.1 8.2 4.0 0.47 9.5 0.2 1.9 2 0 0 2 2 2 0 Enoyl-CoA hydratase/isomerase family MAP65_ASE1 PF03999.7 EIE91357.1 - 2.2e-59 201.6 34.7 4.8e-59 200.5 24.0 1.5 1 1 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) Chordopox_G3 PF06129.7 EIE91357.1 - 0.067 13.3 0.3 0.35 11.0 0.1 2.4 2 0 0 2 2 2 0 Chordopoxvirus G3 protein DUF2164 PF09932.4 EIE91357.1 - 0.096 12.4 3.2 2.4 7.9 0.1 3.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2164) DUF1664 PF07889.7 EIE91357.1 - 3.6 7.4 15.0 0.29 10.9 0.1 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) Robl_LC7 PF03259.12 EIE91358.1 - 1.2e-21 76.0 0.1 1.3e-21 75.9 0.1 1.0 1 0 0 1 1 1 1 Roadblock/LC7 domain BROMI PF14961.1 EIE91358.1 - 0.011 12.9 0.1 0.012 12.8 0.0 1.0 1 0 0 1 1 1 0 Broad-minded protein GatB_N PF02934.10 EIE91358.1 - 0.099 11.4 0.2 0.11 11.3 0.1 1.0 1 0 0 1 1 1 0 GatB/GatE catalytic domain HLH PF00010.21 EIE91359.1 - 1.5e-16 59.7 0.2 1.5e-16 59.7 0.1 1.7 1 1 1 2 2 2 1 Helix-loop-helix DNA-binding domain SET PF00856.23 EIE91360.1 - 1.7e-25 90.2 2.2 1.1e-24 87.5 0.1 3.3 3 1 0 3 3 3 1 SET domain Med26 PF08711.6 EIE91360.1 - 1e-07 31.3 2.0 2.6e-07 30.0 0.5 2.2 2 0 0 2 2 2 1 TFIIS helical bundle-like domain SRI PF08236.6 EIE91360.1 - 3e-05 23.8 1.5 0.0001 22.2 1.1 1.9 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain WW PF00397.21 EIE91360.1 - 0.00039 20.2 0.1 0.00039 20.2 0.1 2.6 2 0 0 2 2 2 1 WW domain PRESAN PF09687.5 EIE91360.1 - 0.081 12.9 0.2 0.081 12.9 0.1 3.4 3 0 0 3 3 3 0 Plasmodium RESA N-terminal PIN_4 PF13638.1 EIE91361.1 - 1.6e-09 37.9 0.6 8.1e-07 29.2 0.4 2.4 1 1 0 1 1 1 1 PIN domain Ribosomal_L14e PF01929.12 EIE91362.1 - 4e-25 87.9 5.3 6.3e-25 87.3 3.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 EIE91362.1 - 0.00017 21.1 0.4 0.0004 20.0 0.3 1.6 1 0 0 1 1 1 1 KOW motif U6-snRNA_bdg PF10596.4 EIE91362.1 - 0.002 17.5 0.3 0.0029 17.0 0.2 1.2 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 Snf7 PF03357.16 EIE91363.1 - 4.9e-36 123.6 19.9 6.9e-36 123.1 13.8 1.3 1 1 0 1 1 1 1 Snf7 NPV_P10 PF05531.7 EIE91363.1 - 0.0031 17.7 9.9 0.0034 17.6 2.5 3.1 2 1 1 3 3 3 1 Nucleopolyhedrovirus P10 protein Phasin PF05597.6 EIE91363.1 - 0.0052 16.5 4.3 0.01 15.5 3.0 1.6 1 0 0 1 1 1 1 Poly(hydroxyalcanoate) granule associated protein (phasin) CBM_3 PF00942.13 EIE91363.1 - 0.02 14.8 0.3 0.051 13.6 0.1 1.7 1 1 1 2 2 2 0 Cellulose binding domain zf-C4H2 PF10146.4 EIE91363.1 - 0.026 14.5 3.0 0.04 13.9 2.1 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein DUF1974 PF09317.6 EIE91363.1 - 0.029 13.7 1.7 0.039 13.3 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1974) DUF2730 PF10805.3 EIE91363.1 - 0.068 12.9 3.6 0.27 10.9 1.3 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF2730) COG6 PF06419.6 EIE91363.1 - 0.085 10.9 7.3 0.12 10.4 5.1 1.1 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 DUF515 PF04415.7 EIE91363.1 - 0.13 10.4 3.8 0.21 9.7 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) BLOC1_2 PF10046.4 EIE91363.1 - 0.13 12.3 8.5 0.2 11.8 5.2 1.9 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF342 PF03961.8 EIE91363.1 - 0.14 10.5 3.9 0.16 10.3 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Mnd1 PF03962.10 EIE91363.1 - 0.15 11.6 9.6 0.085 12.5 4.7 1.9 2 0 0 2 2 2 0 Mnd1 family DUF4238 PF14022.1 EIE91363.1 - 0.16 11.2 2.6 0.22 10.7 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4238) DUF2229 PF09989.4 EIE91363.1 - 0.24 10.8 2.8 0.26 10.6 1.2 1.5 1 1 1 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) DUF4613 PF15390.1 EIE91363.1 - 0.26 9.4 2.6 0.31 9.1 1.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Presenilin PF01080.12 EIE91363.1 - 0.3 9.8 2.6 0.34 9.6 1.8 1.2 1 0 0 1 1 1 0 Presenilin V_ATPase_I PF01496.14 EIE91363.1 - 0.55 8.0 3.4 0.68 7.7 2.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CorA PF01544.13 EIE91363.1 - 6.7 5.6 8.5 1.2 8.1 1.8 2.1 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein CTD_bind PF04818.8 EIE91364.1 - 3.2e-06 27.2 0.0 9.4e-06 25.7 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase II-binding domain. DNA_RNApol_7kD PF03604.8 EIE91364.1 - 0.0022 17.3 0.6 0.1 12.0 0.0 2.4 2 0 0 2 2 2 1 DNA directed RNA polymerase, 7 kDa subunit zf-H2C2_2 PF13465.1 EIE91364.1 - 0.042 14.1 1.5 1.4 9.3 0.0 2.6 2 0 0 2 2 2 0 Zinc-finger double domain Vma12 PF11712.3 EIE91364.1 - 0.078 12.6 2.2 0.17 11.5 1.5 1.6 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase zf-C2H2_4 PF13894.1 EIE91364.1 - 0.11 12.8 1.2 16 6.1 0.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-RING_3 PF14369.1 EIE91364.1 - 0.17 11.9 0.2 0.42 10.6 0.1 1.6 1 0 0 1 1 1 0 zinc-finger zinc_ribbon_5 PF13719.1 EIE91364.1 - 0.29 10.7 1.9 3.9 7.1 0.0 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-trcl PF13451.1 EIE91364.1 - 0.34 10.5 2.9 2.1 8.0 0.5 2.4 2 0 0 2 2 2 0 Probable zinc-binding domain zf-C2HC_2 PF13913.1 EIE91364.1 - 4.9 6.9 6.0 0.3 10.7 0.2 1.9 2 0 0 2 2 2 0 zinc-finger of a C2HC-type GCR1_C PF12550.3 EIE91365.1 - 5.1e-26 90.3 0.7 5.1e-25 87.1 0.2 2.6 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes STE PF02200.11 EIE91366.1 - 0.055 13.6 0.8 0.11 12.6 0.6 1.6 1 1 0 1 1 1 0 STE like transcription factor DUF2482 PF10655.4 EIE91368.1 - 0.012 15.6 0.2 0.02 14.9 0.2 1.4 1 0 0 1 1 1 0 Hypothetical protein of unknown function (DUF2482) Ribosomal_L30_N PF08079.7 EIE91369.1 - 9.5e-21 73.5 18.3 1.9e-20 72.6 12.7 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 EIE91369.1 - 3.6e-19 68.1 0.9 9.2e-19 66.7 0.6 1.7 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Mpp10 PF04006.7 EIE91369.1 - 0.22 9.8 4.7 0.3 9.4 3.3 1.1 1 0 0 1 1 1 0 Mpp10 protein P22_AR_C PF10548.4 EIE91370.1 - 0.00045 20.0 0.7 0.00093 19.0 0.5 1.5 1 0 0 1 1 1 1 P22AR C-terminal domain TMF_TATA_bd PF12325.3 EIE91370.1 - 0.0062 16.2 3.6 0.012 15.2 2.5 1.5 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding Clathrin_lg_ch PF01086.12 EIE91370.1 - 0.049 13.5 4.8 0.068 13.0 3.3 1.3 1 0 0 1 1 1 0 Clathrin light chain Phage_Mu_Gam PF07352.7 EIE91370.1 - 0.19 11.2 9.8 0.22 11.0 4.8 2.5 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein TMF_DNA_bd PF12329.3 EIE91370.1 - 0.41 10.4 7.2 0.59 9.9 0.8 3.0 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding UCH_1 PF13423.1 EIE91370.1 - 0.51 9.7 6.2 0.62 9.4 4.3 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase IncA PF04156.9 EIE91370.1 - 0.93 9.0 6.1 1.7 8.2 4.2 1.5 1 0 0 1 1 1 0 IncA protein DAP PF15228.1 EIE91371.1 - 0.00014 22.5 4.4 0.0002 22.0 3.0 1.3 1 0 0 1 1 1 1 Death-associated protein DUF4602 PF15375.1 EIE91371.1 - 0.17 11.9 4.2 0.23 11.5 2.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4602) Merozoite_SPAM PF07133.6 EIE91371.1 - 0.18 11.6 4.7 0.21 11.4 3.2 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) vMSA PF00695.14 EIE91371.1 - 0.29 10.2 2.3 0.3 10.2 1.6 1.1 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Pex19 PF04614.7 EIE91372.1 - 2.6e-60 204.1 24.9 2.6e-60 204.1 17.3 2.0 1 1 1 2 2 2 1 Pex19 protein family DUF445 PF04286.7 EIE91372.1 - 0.045 13.2 11.0 1.7 8.0 4.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF445) Host_attach PF10116.4 EIE91372.1 - 0.052 13.7 4.5 0.33 11.1 0.8 2.7 1 1 1 2 2 2 0 Protein required for attachment to host cells SpoVAD PF07451.6 EIE91372.1 - 0.062 11.7 1.1 0.095 11.1 0.8 1.3 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) GlutR_dimer PF00745.15 EIE91372.1 - 0.063 13.2 2.5 0.45 10.4 0.2 3.1 2 1 2 4 4 4 0 Glutamyl-tRNAGlu reductase, dimerisation domain DUF2428 PF10350.4 EIE91372.1 - 0.092 11.7 0.1 0.21 10.5 0.0 1.6 2 0 0 2 2 2 0 Putative death-receptor fusion protein (DUF2428) Methyltransf_29 PF03141.11 EIE91372.1 - 0.14 10.4 4.4 0.078 11.2 1.8 1.5 1 1 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase DUF479 PF04336.7 EIE91372.1 - 0.15 12.1 1.6 0.85 9.7 0.3 2.5 2 1 0 2 2 2 0 Protein of unknown function, DUF479 DUF573 PF04504.9 EIE91372.1 - 0.63 10.3 4.9 0.28 11.4 0.3 2.6 1 1 0 2 2 2 0 Protein of unknown function, DUF573 FliE PF02049.13 EIE91372.1 - 0.89 9.6 12.6 2.5 8.2 1.3 3.5 1 1 2 4 4 4 0 Flagellar hook-basal body complex protein FliE DUF4061 PF13270.1 EIE91372.1 - 0.99 9.5 8.2 2.2 8.3 1.3 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4061) FA_desaturase PF00487.19 EIE91373.1 - 4.6e-17 62.3 18.9 7.8e-17 61.5 13.1 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Lar_restr_allev PF14354.1 EIE91374.1 - 0.0033 17.7 1.9 0.008 16.4 0.3 2.2 2 0 0 2 2 2 1 Restriction alleviation protein Lar Zn-ribbon_8 PF09723.5 EIE91374.1 - 0.042 13.7 2.4 5.5 7.0 0.1 2.5 2 0 0 2 2 2 0 Zinc ribbon domain DUF2296 PF10058.4 EIE91374.1 - 0.053 13.2 0.3 0.13 12.0 0.2 1.6 1 0 0 1 1 1 0 Predicted integral membrane metal-binding protein (DUF2296) LRR_4 PF12799.2 EIE91374.1 - 0.066 12.8 0.0 0.22 11.2 0.0 1.8 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) Spectrin PF00435.16 EIE91374.1 - 0.067 13.4 0.3 0.067 13.4 0.2 2.3 2 0 0 2 2 2 0 Spectrin repeat zf-H2C2_2 PF13465.1 EIE91374.1 - 0.15 12.4 3.0 12 6.3 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger double domain TPR_MLP1_2 PF07926.7 EIE91374.1 - 0.15 11.8 4.3 0.038 13.7 0.6 1.8 2 0 0 2 2 1 0 TPR/MLP1/MLP2-like protein OrfB_Zn_ribbon PF07282.6 EIE91374.1 - 0.17 11.5 0.7 6.7 6.4 0.1 2.4 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Zn_Tnp_IS1595 PF12760.2 EIE91374.1 - 0.2 11.4 4.6 0.73 9.6 3.3 2.0 1 1 0 1 1 1 0 Transposase zinc-ribbon domain DnaJ_CXXCXGXG PF00684.14 EIE91374.1 - 0.2 11.7 1.8 0.41 10.7 1.2 1.5 1 0 0 1 1 1 0 DnaJ central domain DUF4140 PF13600.1 EIE91374.1 - 0.21 12.0 3.7 1.8 9.0 0.4 2.6 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) HypA PF01155.14 EIE91374.1 - 0.25 11.0 2.0 5.2 6.7 0.1 2.3 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Zn_Tnp_IS1 PF03811.8 EIE91374.1 - 0.32 10.5 2.9 0.77 9.3 2.0 1.7 1 0 0 1 1 1 0 InsA N-terminal domain zf-ISL3 PF14690.1 EIE91374.1 - 0.86 9.6 4.5 0.62 10.1 0.3 2.5 1 1 1 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 FlgN PF05130.7 EIE91374.1 - 1.1 9.4 10.2 3.3 7.9 1.0 2.9 3 0 0 3 3 3 0 FlgN protein ADIP PF11559.3 EIE91374.1 - 1.4 8.8 8.7 4.3 7.2 1.3 2.5 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF2046 PF09755.4 EIE91374.1 - 2 7.2 9.7 0.22 10.3 1.0 2.8 2 1 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) RVT_1 PF00078.22 EIE91375.1 - 1.2e-32 112.9 0.0 2.5e-32 112.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ish1 PF10281.4 EIE91376.1 - 1.1e-05 25.4 0.8 1.1e-05 25.4 0.6 3.3 3 0 0 3 3 3 1 Putative stress-responsive nuclear envelope protein WbqC PF08889.6 EIE91376.1 - 0.0083 15.6 4.4 0.34 10.3 0.2 2.9 2 1 0 3 3 3 2 WbqC-like protein family BssS PF13991.1 EIE91376.1 - 0.082 12.6 1.2 0.82 9.4 0.0 3.0 3 0 0 3 3 3 0 BssS protein family DUF4631 PF15450.1 EIE91376.1 - 0.084 11.1 10.6 0.031 12.5 3.6 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4631) Bac_DNA_binding PF00216.16 EIE91376.1 - 0.098 12.6 10.6 1.9 8.5 0.2 4.3 4 1 0 4 4 4 0 Bacterial DNA-binding protein DUF1319 PF07028.6 EIE91376.1 - 0.36 11.0 12.7 1.3 9.2 2.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1319) Pkinase PF00069.20 EIE91377.1 - 2.9e-59 200.3 0.2 5.7e-57 192.8 0.0 2.7 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIE91377.1 - 1.4e-29 102.9 0.1 4.3e-28 98.0 0.0 2.2 1 1 1 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE91377.1 - 5.3e-05 22.3 0.0 9.6e-05 21.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EIE91377.1 - 0.0056 16.4 0.1 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EIE91377.1 - 0.015 14.3 0.1 0.038 13.0 0.1 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EIE91377.1 - 0.035 13.4 0.1 0.089 12.1 0.1 1.6 1 0 0 1 1 1 0 RIO1 family NT5C PF06941.7 EIE91378.1 - 3.1e-14 52.9 1.4 1.8e-13 50.4 1.0 2.0 1 1 0 1 1 1 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) HAD_2 PF13419.1 EIE91378.1 - 9.5e-05 22.6 0.3 0.00027 21.2 0.2 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.9 EIE91378.1 - 0.0052 16.1 1.1 0.04 13.2 0.7 2.1 1 1 0 1 1 1 1 HAD superfamily, subfamily IIIB (Acid phosphatase) DUF3657 PF12394.3 EIE91378.1 - 0.017 15.2 0.5 0.075 13.1 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3657) Hydrolase PF00702.21 EIE91378.1 - 0.02 15.3 0.0 0.043 14.2 0.0 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase ATLF PF07737.6 EIE91378.1 - 0.027 13.8 0.0 0.056 12.8 0.0 1.5 1 0 0 1 1 1 0 Anthrax toxin lethal factor, N- and C-terminal domain Hydrolase_3 PF08282.7 EIE91378.1 - 0.032 13.8 1.4 0.1 12.1 0.2 2.3 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase TMP-TENI PF02581.12 EIE91378.1 - 0.05 12.7 0.0 0.082 12.0 0.0 1.3 1 0 0 1 1 1 0 Thiamine monophosphate synthase/TENI HAD PF12710.2 EIE91378.1 - 0.056 13.5 0.1 0.085 13.0 0.1 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase PNK3P PF08645.6 EIE91378.1 - 0.14 11.5 0.7 1.6 8.1 0.5 2.3 1 1 0 1 1 1 0 Polynucleotide kinase 3 phosphatase Homeobox_KN PF05920.6 EIE91381.1 - 7.1e-20 70.4 0.7 1.4e-19 69.4 0.5 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 EIE91381.1 - 2.8e-07 30.0 0.2 6.6e-07 28.8 0.2 1.7 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 EIE91381.1 - 0.019 14.0 0.0 0.034 13.2 0.0 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez EST1 PF10374.4 EIE91381.1 - 0.023 14.7 0.9 0.23 11.4 0.2 2.1 2 0 0 2 2 2 0 Telomerase activating protein Est1 CBM_21 PF03370.8 EIE91382.1 - 1.2e-25 89.6 1.7 2.6e-25 88.5 1.2 1.6 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit CBM_25 PF03423.8 EIE91382.1 - 0.0072 16.3 0.1 0.02 14.9 0.1 1.8 1 0 0 1 1 1 1 Carbohydrate binding domain (family 25) ECIST_Cterm PF14784.1 EIE91382.1 - 0.037 13.9 0.0 0.092 12.6 0.0 1.7 1 0 0 1 1 1 0 C-terminal domain of the ECSIT protein MFS_1 PF07690.11 EIE91383.1 - 2.6e-24 85.6 43.6 2.8e-23 82.2 30.2 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily DAGK_cat PF00781.19 EIE91383.1 - 8.1e-22 77.0 0.0 1.6e-21 76.1 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Sugar_tr PF00083.19 EIE91383.1 - 1.3e-10 40.4 11.6 1.3e-10 40.4 8.0 2.9 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 EIE91383.1 - 3.1e-10 38.8 12.0 2.9e-08 32.4 8.2 2.7 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF1206 PF06724.6 EIE91383.1 - 0.0094 15.6 4.7 0.055 13.2 3.2 2.4 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1206) CitG PF01874.11 EIE91384.1 - 0.12 11.5 1.1 0.22 10.7 0.7 1.4 1 0 0 1 1 1 0 ATP:dephospho-CoA triphosphoribosyl transferase SPC22 PF04573.7 EIE91384.1 - 0.3 10.2 9.1 0.58 9.3 6.3 1.4 1 0 0 1 1 1 0 Signal peptidase subunit Pox_A_type_inc PF04508.7 EIE91384.1 - 0.83 9.6 0.0 0.83 9.6 0.0 4.3 4 1 0 4 4 4 0 Viral A-type inclusion protein repeat RraB PF06877.6 EIE91384.1 - 2.9 8.5 14.9 0.7 10.5 3.0 2.9 2 0 0 2 2 2 0 Regulator of ribonuclease activity B Arch_fla_DE PF04659.8 EIE91385.1 - 0.04 13.7 0.1 0.045 13.5 0.0 1.0 1 0 0 1 1 1 0 Archaeal flagella protein Arrestin_C PF02752.17 EIE91386.1 - 2.3e-10 40.7 0.0 3.8e-08 33.5 0.0 2.9 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EIE91386.1 - 5.2e-07 29.5 0.0 1.4e-06 28.1 0.0 1.8 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain TIP41 PF04176.8 EIE91386.1 - 0.017 14.3 0.2 0.036 13.3 0.1 1.5 1 0 0 1 1 1 0 TIP41-like family LDB19 PF13002.2 EIE91386.1 - 0.024 14.1 0.0 0.045 13.2 0.0 1.4 1 0 0 1 1 1 0 Arrestin_N terminal like HELP PF03451.9 EIE91386.1 - 0.07 12.6 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 HELP motif RGS PF00615.14 EIE91387.1 - 2.8e-30 104.8 0.2 9.4e-30 103.1 0.0 2.0 2 0 0 2 2 2 1 Regulator of G protein signaling domain DEP PF00610.16 EIE91387.1 - 4e-12 45.6 0.2 6.6e-06 25.7 0.0 3.1 2 1 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF4441 PF14536.1 EIE91387.1 - 0.071 13.0 1.2 0.21 11.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4441) Glyco_hydro_18 PF00704.23 EIE91388.1 - 1.2e-12 48.0 0.8 4.1e-11 42.9 0.0 2.3 1 1 1 2 2 2 2 Glycosyl hydrolases family 18 GATA PF00320.22 EIE91389.1 - 3.8e-19 67.7 4.6 8.6e-19 66.6 3.2 1.7 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.7 EIE91389.1 - 0.071 12.4 1.2 0.16 11.3 0.9 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding Cytochrom_c3_2 PF14537.1 EIE91389.1 - 0.11 12.8 4.6 0.15 12.4 2.2 1.9 1 1 1 2 2 2 0 Cytochrome c3 DZR PF12773.2 EIE91389.1 - 0.38 10.5 4.1 3.4 7.5 3.2 2.1 1 1 1 2 2 2 0 Double zinc ribbon SR-25 PF10500.4 EIE91389.1 - 3.2 7.1 16.1 0.21 11.0 3.1 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein OrfB_Zn_ribbon PF07282.6 EIE91389.1 - 8.2 6.1 8.5 1.4 8.6 2.0 2.3 2 0 0 2 2 2 0 Putative transposase DNA-binding domain TauD PF02668.11 EIE91390.1 - 9.7e-47 159.7 0.0 1.2e-46 159.4 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family RPA_C PF08784.6 EIE91393.1 - 1.8e-10 41.1 0.2 3.8e-10 40.0 0.1 1.6 1 0 0 1 1 1 1 Replication protein A C terminal tRNA_anti-codon PF01336.20 EIE91393.1 - 1.3e-07 31.3 0.2 2.4e-07 30.4 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF2683 PF10884.3 EIE91393.1 - 0.029 14.2 0.0 0.16 11.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2683) Sigma70_r2 PF04542.9 EIE91393.1 - 0.055 13.0 0.0 2.4 7.8 0.0 2.3 2 0 0 2 2 2 0 Sigma-70 region 2 DNA_pol_alpha_N PF12254.3 EIE91393.1 - 0.15 11.9 0.2 0.15 11.9 0.1 2.0 2 0 0 2 2 2 0 DNA polymerase alpha subunit p180 N terminal Acetyltransf_1 PF00583.19 EIE91394.1 - 6.7e-10 38.8 0.0 9.8e-10 38.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EIE91394.1 - 6e-09 35.9 0.0 9e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EIE91394.1 - 3.4e-05 23.7 0.0 0.00016 21.4 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EIE91394.1 - 0.00094 19.2 0.0 0.0013 18.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 EIE91394.1 - 0.0057 16.2 0.0 0.0092 15.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EIE91394.1 - 0.016 14.9 0.0 0.033 13.9 0.0 1.7 1 1 0 1 1 1 0 FR47-like protein Acetyltransf_3 PF13302.1 EIE91394.1 - 0.029 14.5 0.0 0.04 14.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MGS PF02142.17 EIE91394.1 - 0.047 13.6 0.0 0.082 12.8 0.0 1.4 1 0 0 1 1 1 0 MGS-like domain Acetyltransf_4 PF13420.1 EIE91394.1 - 0.14 12.0 0.1 0.48 10.3 0.1 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-CCHC PF00098.18 EIE91395.1 - 1e-06 28.3 9.7 0.00021 21.0 0.5 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.1 EIE91395.1 - 0.043 13.4 0.6 0.15 11.7 0.4 2.0 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 EIE91395.1 - 0.11 12.2 4.9 3.5 7.3 0.5 2.6 2 0 0 2 2 2 0 Zinc knuckle RVT_1 PF00078.22 EIE91396.1 - 7.8e-40 136.5 0.1 3e-39 134.6 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.1 EIE91396.1 - 1e-07 32.1 0.7 3.4e-07 30.4 0.5 1.9 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Exo_endo_phos_2 PF14529.1 EIE91396.1 - 0.0051 16.4 0.2 0.014 14.9 0.1 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RVT_1 PF00078.22 EIE91397.1 - 2.6e-23 82.5 0.0 5.5e-23 81.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.1 EIE91397.1 - 0.0041 17.4 0.4 0.012 15.9 0.3 1.9 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Rtt102p PF09510.5 EIE91398.1 - 0.18 11.7 0.1 0.18 11.7 0.1 2.8 2 1 1 3 3 3 0 Rtt102p-like transcription regulator protein zf-CCHC_4 PF14392.1 EIE91398.1 - 6.5 6.5 9.8 1.1 8.9 0.6 2.9 3 0 0 3 3 3 0 Zinc knuckle Pex2_Pex12 PF04757.9 EIE91399.1 - 1.7e-49 168.3 5.2 2.2e-49 167.9 3.6 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 EIE91399.1 - 2.7e-09 36.9 2.5 4.5e-09 36.1 1.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIE91399.1 - 1.3e-06 28.1 2.3 2.1e-06 27.4 1.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EIE91399.1 - 2.1e-05 24.1 1.4 3.2e-05 23.4 0.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIE91399.1 - 0.00054 19.5 1.8 0.00093 18.8 1.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EIE91399.1 - 0.0037 17.1 5.3 0.007 16.2 3.7 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING XPC-binding PF09280.6 EIE91399.1 - 0.096 12.1 0.0 0.29 10.6 0.0 1.8 1 1 1 2 2 2 0 XPC-binding domain Beach PF02138.13 EIE91400.1 - 6e-112 373.4 0.0 1.7e-111 372.0 0.0 1.8 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.1 EIE91400.1 - 1.2e-14 54.0 0.0 4.4e-14 52.2 0.0 2.0 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.1 EIE91401.1 - 0.0003 21.0 0.0 0.00048 20.3 0.0 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily GDI PF00996.13 EIE91402.1 - 1.5e-69 234.3 2.1 3.9e-35 121.0 0.8 3.1 1 1 1 2 2 2 2 GDP dissociation inhibitor YIF1 PF03878.10 EIE91403.1 - 3.8e-75 252.1 4.0 5.3e-75 251.6 2.7 1.1 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.12 EIE91403.1 - 0.11 11.9 8.9 0.084 12.3 4.9 1.6 1 1 0 1 1 1 0 Yip1 domain Peptidase_S8 PF00082.17 EIE91405.1 - 5.8e-23 81.4 8.8 6.2e-19 68.2 1.3 2.6 1 1 1 2 2 2 2 Subtilase family Pyridoxal_deC PF00282.14 EIE91406.1 - 6.5e-50 169.6 0.0 1.1e-47 162.2 0.0 2.1 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DDE_3 PF13358.1 EIE91407.1 - 2.9e-07 30.3 0.6 1.7e-06 27.8 0.1 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_3 PF13358.1 EIE91409.1 - 7.1e-19 67.9 0.0 9.6e-19 67.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE91409.1 - 0.017 15.2 0.0 0.034 14.2 0.0 1.6 1 1 0 1 1 1 0 Integrase core domain Myb_DNA-bind_5 PF13873.1 EIE91409.1 - 0.057 13.3 0.7 5.2 7.0 0.2 2.5 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain DUF1033 PF06279.6 EIE91409.1 - 0.067 13.0 0.3 0.11 12.2 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1033) DDE_3 PF13358.1 EIE91410.1 - 5.1e-19 68.4 1.2 7.9e-19 67.8 0.4 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease RVT_1 PF00078.22 EIE91411.1 - 9.4e-05 21.8 0.0 0.00014 21.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_3 PF13358.1 EIE91412.1 - 2.3e-15 56.6 0.0 4.7e-15 55.6 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE91412.1 - 6.5e-11 42.1 1.2 1.1e-10 41.4 0.2 1.9 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 EIE91412.1 - 0.0059 16.7 0.2 0.014 15.5 0.0 1.7 2 0 0 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.1 EIE91412.1 - 0.016 14.8 0.1 0.042 13.4 0.1 1.7 1 0 0 1 1 1 0 Homeodomain-like domain HTH_30 PF13556.1 EIE91412.1 - 0.049 13.2 0.0 0.51 9.9 0.0 2.2 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain DDE_3 PF13358.1 EIE91413.1 - 3.8e-20 72.1 0.4 5.7e-20 71.5 0.3 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4160 PF13711.1 EIE91413.1 - 1.6 8.6 5.3 22 4.9 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4160) RVT_1 PF00078.22 EIE91414.1 - 1e-21 77.2 0.1 1.8e-21 76.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.12 EIE91414.1 - 8.7e-08 32.1 0.2 2e-07 30.9 0.1 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein Asp_protease_2 PF13650.1 EIE91414.1 - 1e-07 32.3 0.1 3.7e-07 30.5 0.1 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EIE91414.1 - 7.9e-06 25.6 0.1 2.2e-05 24.1 0.1 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.18 EIE91414.1 - 0.00094 19.0 1.0 0.0018 18.1 0.7 1.5 1 0 0 1 1 1 1 Zinc knuckle Autophagy_N PF03986.8 EIE91414.1 - 0.025 14.3 0.3 0.054 13.2 0.2 1.5 1 0 0 1 1 1 0 Autophagocytosis associated protein (Atg3), N-terminal domain RVP PF00077.15 EIE91414.1 - 0.12 12.2 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease LAT PF15234.1 EIE91414.1 - 1.2 8.5 7.0 3 7.2 1.3 2.3 2 0 0 2 2 2 0 Linker for activation of T-cells rve PF00665.21 EIE91415.1 - 4.1e-21 75.2 0.0 5.8e-21 74.8 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain AcylCoA_dehyd_C PF12186.3 EIE91415.1 - 0.075 12.8 1.5 0.15 11.9 0.7 1.7 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase C terminal rve_3 PF13683.1 EIE91415.1 - 0.076 12.5 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain DUF1203 PF06718.6 EIE91416.1 - 0.085 12.6 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1203) Transposase_21 PF02992.9 EIE91417.1 - 7.3e-22 77.5 0.0 1.1e-21 76.9 0.0 1.2 1 0 0 1 1 1 1 Transposase family tnp2 DUF1258 PF06869.7 EIE91417.1 - 0.002 17.2 0.0 0.0031 16.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) DUF1759 PF03564.10 EIE91418.1 - 0.00014 21.7 0.4 0.00021 21.1 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) Retrotrans_gag PF03732.12 EIE91418.1 - 0.0006 19.8 0.3 0.0016 18.4 0.0 1.8 2 0 0 2 2 2 1 Retrotransposon gag protein RVT_1 PF00078.22 EIE91419.1 - 8e-15 54.7 0.3 8.4e-07 28.5 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Spuma_A9PTase PF03539.9 EIE91419.1 - 0.011 15.7 0.2 0.037 13.9 0.0 1.9 1 1 1 2 2 2 0 Spumavirus aspartic protease (A9) rve PF00665.21 EIE91420.1 - 9.2e-28 96.7 0.0 2.8e-27 95.1 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.1 EIE91420.1 - 1.3e-05 24.6 0.1 5.1e-05 22.7 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.5 EIE91420.1 - 0.0026 17.1 0.1 0.013 14.9 0.0 2.2 2 0 0 2 2 2 1 His(2)-Cys(2) zinc finger Retrotrans_gag PF03732.12 EIE91421.1 - 2.4e-06 27.5 0.7 8.3e-06 25.7 0.0 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein Asp_protease_2 PF13650.1 EIE91421.1 - 3.1e-06 27.6 0.0 9e-06 26.1 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease UBN2_2 PF14227.1 EIE91421.1 - 2.5e-05 23.8 0.7 0.00041 19.8 0.1 3.0 3 1 0 3 3 3 1 gag-polypeptide of LTR copia-type gag-asp_proteas PF13975.1 EIE91421.1 - 9.9e-05 22.0 0.0 0.0002 21.0 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease UBN2 PF14223.1 EIE91421.1 - 0.00021 21.0 0.9 0.1 12.3 0.1 2.5 2 0 0 2 2 2 2 gag-polypeptide of LTR copia-type rve PF00665.21 EIE91422.1 - 1.7e-07 31.3 0.2 5.7e-07 29.6 0.0 2.0 2 1 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.5 EIE91422.1 - 0.0068 15.7 1.1 0.015 14.7 0.1 2.0 2 0 0 2 2 2 1 His(2)-Cys(2) zinc finger Asp_protease PF09668.5 EIE91423.1 - 3.4e-10 39.5 0.0 5.4e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 EIE91423.1 - 5.3e-08 33.2 0.0 1.5e-07 31.7 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 EIE91423.1 - 3.8e-06 26.7 0.3 1.9e-05 24.4 0.0 2.3 2 1 1 3 3 3 1 Retroviral aspartyl protease RVP_2 PF08284.6 EIE91423.1 - 5.6e-06 26.3 0.0 1.4e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EIE91423.1 - 0.00033 20.4 0.1 0.00062 19.5 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease NOA36 PF06524.7 EIE91423.1 - 2.5 7.2 7.0 5.2 6.2 4.8 1.5 1 0 0 1 1 1 0 NOA36 protein DUF1759 PF03564.10 EIE91424.1 - 0.00041 20.1 0.4 0.00041 20.1 0.3 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1759) Transposase_21 PF02992.9 EIE91425.1 - 1.7e-22 79.6 0.1 3.6e-22 78.5 0.1 1.5 1 0 0 1 1 1 1 Transposase family tnp2 3HCDH_N PF02737.13 EIE91425.1 - 0.15 11.7 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Transposase_21 PF02992.9 EIE91427.1 - 1.3e-22 80.0 0.1 1.3e-22 80.0 0.1 1.6 2 0 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.1 EIE91427.1 - 2e-05 24.0 0.5 4.7e-05 22.8 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Lzipper-MIP1 PF14389.1 EIE91428.1 - 0.0047 17.0 0.4 0.013 15.5 0.3 1.8 1 0 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 IncA PF04156.9 EIE91428.1 - 0.18 11.3 1.6 0.32 10.5 1.1 1.4 1 0 0 1 1 1 0 IncA protein SRR PF07709.6 EIE91428.1 - 0.23 11.7 4.4 5.5 7.6 0.0 3.6 3 0 0 3 3 3 0 Seven Residue Repeat ChaB PF06150.7 EIE91428.1 - 0.25 11.1 0.2 0.25 11.1 0.1 2.2 3 0 0 3 3 3 0 ChaB DDE_3 PF13358.1 EIE91429.1 - 2.8e-13 49.8 0.2 4.6e-13 49.1 0.1 1.4 1 1 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE91429.1 - 0.0017 18.4 0.0 0.003 17.6 0.0 1.6 1 1 0 1 1 1 1 Integrase core domain Y1_Tnp PF01797.11 EIE91429.1 - 0.029 14.2 0.1 0.22 11.3 0.0 2.0 2 0 0 2 2 2 0 Transposase IS200 like DUF2284 PF10050.4 EIE91429.1 - 0.095 12.2 0.3 0.16 11.5 0.2 1.3 1 0 0 1 1 1 0 Predicted metal-binding protein (DUF2284) HMG_box_2 PF09011.5 EIE91429.1 - 0.14 12.5 1.1 0.84 10.0 0.2 2.1 2 0 0 2 2 2 0 HMG-box domain DDE_3 PF13358.1 EIE91430.1 - 4.3e-21 75.2 0.4 5.9e-21 74.7 0.3 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE91431.1 - 1.2e-08 34.8 0.9 2.5e-08 33.8 0.6 1.6 1 0 0 1 1 1 1 Transposase RecX PF02631.11 EIE91431.1 - 0.034 14.3 0.5 0.053 13.7 0.3 1.4 1 1 0 1 1 1 0 RecX family rve PF00665.21 EIE91432.1 - 2.9e-20 72.5 0.0 1.1e-19 70.6 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 EIE91432.1 - 4.2e-11 42.6 0.3 1.2e-10 41.0 0.2 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE91432.1 - 5.4e-07 29.1 2.4 1.2e-06 28.0 1.6 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.1 EIE91432.1 - 1.9e-06 28.3 0.1 1.9e-05 25.0 0.1 2.4 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.15 EIE91432.1 - 7.7e-06 25.7 0.1 2.4e-05 24.1 0.1 1.9 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EIE91432.1 - 0.00012 21.7 0.0 0.00029 20.6 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Tudor-knot PF11717.3 EIE91432.1 - 0.0082 15.8 0.9 0.027 14.1 0.6 1.9 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Asp_protease PF09668.5 EIE91432.1 - 0.079 12.5 0.0 0.28 10.7 0.0 1.9 1 0 0 1 1 1 0 Aspartyl protease DDE_3 PF13358.1 EIE91433.1 - 2.2e-20 72.8 0.1 4e-20 72.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE91433.1 - 2.4e-08 33.9 3.4 3.2e-08 33.4 0.3 2.4 1 1 1 2 2 2 1 Transposase HTH_29 PF13551.1 EIE91433.1 - 0.001 19.1 1.7 0.0033 17.5 1.2 1.9 1 1 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_ISL3 PF13542.1 EIE91433.1 - 0.037 13.2 0.6 0.037 13.2 0.4 2.3 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 rve PF00665.21 EIE91433.1 - 0.041 13.9 0.2 0.12 12.4 0.0 1.9 2 1 0 2 2 2 0 Integrase core domain NFRKB_winged PF14465.1 EIE91433.1 - 0.096 12.5 3.3 1.2 8.9 0.6 2.9 2 1 1 3 3 3 0 NFRKB Winged Helix-like HTH_23 PF13384.1 EIE91433.1 - 0.39 10.4 2.9 3.5 7.3 0.2 2.5 2 0 0 2 2 2 0 Homeodomain-like domain HTH_32 PF13565.1 EIE91433.1 - 0.91 10.3 5.6 0.25 12.1 0.5 2.4 3 0 0 3 3 3 0 Homeodomain-like domain RVT_1 PF00078.22 EIE91434.1 - 2.2e-18 66.4 0.0 4.8e-18 65.2 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HTH_Tnp_Tc3_2 PF01498.13 EIE91435.1 - 1.3e-05 25.1 0.9 2e-05 24.5 0.1 1.8 2 0 0 2 2 2 1 Transposase E3_UbLigase_EDD PF11547.3 EIE91435.1 - 0.017 14.6 0.0 0.033 13.6 0.0 1.4 1 0 0 1 1 1 0 E3 ubiquitin ligase EDD Chromo PF00385.19 EIE91436.1 - 1.7e-12 46.8 1.9 2.2e-12 46.4 1.3 1.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain SF3a60_bindingd PF12108.3 EIE91436.1 - 0.068 12.7 0.9 0.097 12.2 0.0 1.7 2 0 0 2 2 2 0 Splicing factor SF3a60 binding domain Mtf2_C PF14061.1 EIE91436.1 - 0.083 12.7 0.2 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 zf-RVT PF13966.1 EIE91437.1 - 0.11 12.7 0.7 0.27 11.5 0.5 1.6 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase Chromo PF00385.19 EIE91438.1 - 5.7e-16 57.9 6.3 1e-13 50.7 0.8 3.6 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.14 EIE91438.1 - 8.5e-07 28.7 0.3 2.5e-05 24.0 0.1 2.5 2 0 0 2 2 2 1 Chromo shadow domain WD40 PF00400.27 EIE91439.1 - 5.2e-61 200.5 22.3 3e-11 42.7 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EIE91439.1 - 8.4e-07 28.8 0.2 9.2e-06 25.4 0.0 2.4 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EIE91439.1 - 0.00031 19.0 10.5 0.079 11.0 0.2 5.0 2 2 2 5 5 5 3 Nucleoporin Nup120/160 Nbas_N PF15492.1 EIE91439.1 - 0.0099 15.0 0.2 2.8 6.9 0.0 2.6 3 0 0 3 3 3 2 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.11 EIE91439.1 - 0.014 13.7 0.0 1.6 6.9 0.0 2.6 2 1 0 2 2 2 0 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 EIE91439.1 - 0.074 11.7 0.6 2.1 6.9 0.3 2.6 2 2 0 2 2 2 0 Nup133 N terminal like DUF3987 PF13148.1 EIE91440.1 - 0.012 14.2 3.1 0.017 13.6 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) zf-C2H2 PF00096.21 EIE91440.1 - 0.077 13.3 1.9 0.14 12.5 1.3 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type APC_CDC26 PF10471.4 EIE91440.1 - 0.16 12.7 5.8 0.086 13.5 1.6 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 TMA7 PF09072.5 EIE91440.1 - 0.56 10.7 4.9 1 9.8 3.4 1.4 1 0 0 1 1 1 0 Translation machinery associated TMA7 CENP-B_dimeris PF09026.5 EIE91441.1 - 0.13 12.4 6.7 0.15 12.2 4.7 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Brevenin PF03032.10 EIE91441.1 - 0.17 11.7 13.9 0.29 11.0 9.6 1.4 1 0 0 1 1 1 0 Brevenin/esculentin/gaegurin/rugosin family Radial_spoke PF04712.7 EIE91441.1 - 0.66 8.6 8.9 0.72 8.5 6.2 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein Nucleoplasmin PF03066.10 EIE91441.1 - 0.67 9.4 8.4 0.93 9.0 5.8 1.2 1 0 0 1 1 1 0 Nucleoplasmin Spore_coat_CotO PF14153.1 EIE91441.1 - 1.4 8.3 7.1 1.7 8.0 4.9 1.1 1 0 0 1 1 1 0 Spore coat protein CotO VID27 PF08553.5 EIE91441.1 - 1.5 6.9 4.2 1.4 7.0 2.9 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein Daxx PF03344.10 EIE91441.1 - 1.9 6.8 8.1 1.9 6.8 5.6 1.0 1 0 0 1 1 1 0 Daxx Family Prp19_bind PF06991.6 EIE91441.1 - 5.4 6.2 9.4 5.5 6.1 6.5 1.0 1 0 0 1 1 1 0 Splicing factor, Prp19-binding domain RVT_1 PF00078.22 EIE91442.1 - 4.1e-10 39.3 0.0 6.9e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EIE91442.1 - 2.9e-05 23.6 0.2 8.1e-05 22.2 0.1 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase NUDIX PF00293.23 EIE91445.1 - 1.9e-15 56.7 0.1 2.4e-15 56.3 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain Rad60-SLD PF11976.3 EIE91446.1 - 1.8e-24 85.1 0.0 2.3e-24 84.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EIE91446.1 - 3e-11 42.5 0.0 3.8e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family PyrI_C PF02748.10 EIE91450.1 - 0.29 10.5 2.5 1.3 8.4 0.1 2.6 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Spore_III_AB PF09548.5 EIE91450.1 - 0.58 9.8 5.6 0.091 12.5 0.6 2.0 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Sec1 PF00995.18 EIE91451.1 - 1.9e-149 498.9 3.3 2.2e-149 498.6 2.3 1.0 1 0 0 1 1 1 1 Sec1 family zf-met PF12874.2 EIE91452.1 - 1.6e-07 31.2 0.1 2.4e-07 30.6 0.1 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EIE91452.1 - 3e-06 27.2 0.1 4.7e-06 26.5 0.1 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-U1 PF06220.7 EIE91452.1 - 0.0035 16.8 0.1 0.0067 15.9 0.1 1.5 1 0 0 1 1 1 1 U1 zinc finger TTKRSYEDQ PF10212.4 EIE91452.1 - 0.042 12.7 0.0 0.069 12.0 0.0 1.3 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein Viral_P18 PF04521.8 EIE91452.1 - 0.11 11.8 2.7 0.1 12.0 0.4 2.0 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein Homeobox PF00046.24 EIE91453.1 - 3e-19 68.3 0.7 6e-19 67.4 0.5 1.5 1 0 0 1 1 1 1 Homeobox domain TOMM6 PF15184.1 EIE91453.1 - 0.04 13.2 0.0 0.078 12.3 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial import receptor subunit TOM6 homolog Pkinase PF00069.20 EIE91454.1 - 1.6e-41 142.2 0.0 4.9e-41 140.6 0.0 1.9 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE91454.1 - 7.7e-30 103.8 0.0 1.6e-29 102.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE91454.1 - 0.00031 19.7 0.0 0.00058 18.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PP1_bind PF15276.1 EIE91454.1 - 0.04 13.9 0.4 0.28 11.2 0.6 2.2 2 0 0 2 2 2 0 Protein phosphatase 1 binding DEAD PF00270.24 EIE91455.1 - 4.4e-42 143.4 0.0 2e-41 141.3 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIE91455.1 - 2.9e-25 87.9 0.0 4.9e-25 87.2 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RanBP PF00641.13 EIE91455.1 - 4.3e-20 70.4 15.4 8.2e-12 44.0 1.8 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others ResIII PF04851.10 EIE91455.1 - 0.013 15.2 0.0 0.041 13.7 0.0 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Ssu72 PF04722.8 EIE91455.1 - 0.21 10.8 0.0 0.38 10.0 0.0 1.3 1 0 0 1 1 1 0 Ssu72-like protein DZR PF12773.2 EIE91455.1 - 0.3 10.9 9.3 0.75 9.6 6.4 1.7 1 1 0 1 1 1 0 Double zinc ribbon NCD3G PF07562.9 EIE91455.1 - 2.6 7.8 10.1 12 5.6 2.5 2.4 2 0 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR Ribosomal_L4 PF00573.17 EIE91456.1 - 8e-70 234.1 0.0 1e-69 233.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Flavokinase PF01687.12 EIE91457.1 - 1.1e-36 125.4 0.2 1e-29 102.9 0.0 2.0 1 1 1 2 2 2 2 Riboflavin kinase Glyco_hydro_18 PF00704.23 EIE91459.1 - 6.3e-63 213.2 10.6 6.3e-63 213.2 7.3 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 Mem_trans PF03547.13 EIE91459.1 - 0.064 11.5 1.1 0.085 11.1 0.8 1.2 1 0 0 1 1 1 0 Membrane transport protein Peptidase_S49_N PF08496.5 EIE91459.1 - 0.25 11.0 13.9 2.1 8.1 6.8 2.2 1 1 1 2 2 2 0 Peptidase family S49 N-terminal Neur_chan_memb PF02932.11 EIE91459.1 - 0.68 9.7 9.0 1.1 9.0 6.2 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Sec10 PF07393.6 EIE91459.1 - 0.94 7.5 10.7 1.3 7.0 7.4 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec10 Mucin PF01456.12 EIE91459.1 - 1 9.0 7.0 1.8 8.3 4.9 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Macoilin PF09726.4 EIE91459.1 - 1.7 6.8 14.6 2.1 6.5 10.1 1.1 1 0 0 1 1 1 0 Transmembrane protein Acyl_transf_1 PF00698.16 EIE91460.1 - 1e-62 212.3 0.0 4.3e-61 207.0 0.0 2.9 3 0 0 3 3 3 1 Acyl transferase domain MaoC_dehydratas PF01575.14 EIE91460.1 - 5.7e-32 109.6 0.3 2.7e-31 107.5 0.0 2.2 2 0 0 2 2 2 1 MaoC like domain DUF1729 PF08354.5 EIE91460.1 - 1.2e-29 101.9 0.7 1.2e-29 101.9 0.5 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1729) ketoacyl-synt PF00109.21 EIE91460.1 - 1.7e-21 76.8 0.3 4.1e-21 75.6 0.0 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.15 EIE91460.1 - 5.6e-16 58.3 0.0 1.4e-15 57.0 0.0 1.8 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.17 EIE91460.1 - 6.6e-09 35.6 0.0 6.6e-09 35.6 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain SHOCT PF09851.4 EIE91460.1 - 0.5 9.9 4.2 15 5.2 1.8 2.8 2 0 0 2 2 2 0 Short C-terminal domain zf-RING_2 PF13639.1 EIE91461.1 - 1.5e-12 47.1 5.9 2.4e-12 46.4 4.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EIE91461.1 - 1.5e-07 31.3 6.8 2.5e-07 30.5 4.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIE91461.1 - 1.6e-07 30.8 4.4 2.7e-07 30.1 3.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIE91461.1 - 2e-07 30.6 3.1 3.2e-07 29.9 2.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 EIE91461.1 - 3e-06 27.2 1.4 6e-06 26.2 1.0 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EIE91461.1 - 1e-05 25.0 6.8 1.6e-05 24.4 4.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 EIE91461.1 - 0.016 14.7 5.1 0.026 14.1 3.5 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 EIE91461.1 - 0.037 13.9 6.3 0.091 12.6 4.4 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING TM_helix PF05552.7 EIE91461.1 - 0.039 13.6 2.3 0.068 12.8 1.6 1.3 1 0 0 1 1 1 0 Conserved TM helix OCD_Mu_crystall PF02423.10 EIE91462.1 - 7.6e-55 185.8 0.2 8.9e-55 185.6 0.1 1.0 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.15 EIE91462.1 - 8e-09 35.7 0.0 1.3e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 EIE91462.1 - 0.0087 16.3 0.0 0.031 14.5 0.0 1.9 2 1 0 2 2 2 1 Putative NAD(P)-binding GFO_IDH_MocA PF01408.17 EIE91462.1 - 0.011 16.2 0.0 0.026 15.0 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Ureide_permease PF07168.6 EIE91463.1 - 0.68 8.5 4.4 0.26 9.9 0.2 1.9 1 1 1 2 2 2 0 Ureide permease zf-HC5HC2H_2 PF13832.1 EIE91464.1 - 1.2e-15 57.4 7.0 1.2e-15 57.4 4.8 2.9 2 1 1 3 3 3 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EIE91464.1 - 8.3e-13 48.3 2.8 8.3e-13 48.3 1.9 2.8 3 0 0 3 3 3 1 PHD-like zinc-binding domain GATA PF00320.22 EIE91464.1 - 4.9e-08 32.1 1.6 4.9e-08 32.1 1.1 3.9 4 0 0 4 4 4 1 GATA zinc finger PHD PF00628.24 EIE91464.1 - 0.017 14.8 7.4 0.017 14.8 5.1 4.9 5 1 1 6 6 6 0 PHD-finger BAH PF01426.13 EIE91465.1 - 4e-17 62.0 0.9 7.9e-17 61.1 0.2 1.7 2 0 0 2 2 2 1 BAH domain PHD PF00628.24 EIE91465.1 - 1.2e-08 34.5 13.8 2.2e-08 33.6 9.6 1.5 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.17 EIE91465.1 - 0.012 15.2 9.6 0.012 15.2 6.6 2.1 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_2 PF13639.1 EIE91465.1 - 0.074 12.8 13.7 0.16 11.8 9.5 1.6 1 0 0 1 1 1 0 Ring finger domain JAB PF01398.16 EIE91466.1 - 1.2e-14 53.9 2.5 4e-14 52.3 0.0 2.7 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 EIE91466.1 - 6.7e-08 32.0 0.0 2.4e-07 30.2 0.0 1.9 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain CBFB_NFYA PF02045.10 EIE91467.1 - 1.3e-30 105.7 6.0 2.1e-30 105.0 4.1 1.3 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Mito_fiss_reg PF05308.6 EIE91467.1 - 0.24 10.7 2.1 0.12 11.7 0.2 1.5 2 0 0 2 2 2 0 Mitochondrial fission regulator RA PF00788.18 EIE91468.1 - 3.4e-06 27.4 0.0 2.1e-05 24.9 0.0 2.0 2 1 0 2 2 2 1 Ras association (RalGDS/AF-6) domain PH PF00169.24 EIE91468.1 - 9e-06 25.8 1.1 0.0038 17.4 0.1 2.4 1 1 1 2 2 2 2 PH domain S10_plectin PF03501.10 EIE91468.1 - 0.11 12.3 0.1 1.3 8.9 0.0 2.3 2 0 0 2 2 2 0 Plectin/S10 domain COG7 PF10191.4 EIE91469.1 - 2.9e-21 75.1 2.0 6.4e-21 73.9 1.4 1.5 1 0 0 1 1 1 1 Golgi complex component 7 (COG7) TPR_11 PF13414.1 EIE91469.1 - 1.6e-13 50.1 1.4 1.9e-12 46.6 0.1 2.4 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 EIE91469.1 - 7.5e-08 31.6 4.7 0.08 12.5 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EIE91469.1 - 3.9e-05 23.2 4.4 0.7 9.9 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EIE91469.1 - 0.00046 20.0 1.2 0.012 15.5 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF3856 PF12968.2 EIE91469.1 - 0.0013 18.5 0.1 0.0039 17.0 0.1 1.8 1 0 0 1 1 1 1 Domain of Unknown Function (DUF3856) UBA PF00627.26 EIE91469.1 - 0.0017 18.1 0.1 0.0041 16.9 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain COG5 PF10392.4 EIE91469.1 - 0.0075 16.2 2.2 0.029 14.3 1.5 2.2 1 1 0 1 1 1 1 Golgi transport complex subunit 5 TPR_16 PF13432.1 EIE91469.1 - 0.036 14.7 1.4 0.14 12.8 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 EIE91469.1 - 0.041 13.6 0.6 13 5.8 0.2 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TrbI PF03743.9 EIE91472.1 - 0.065 12.7 3.7 0.12 11.8 2.6 1.3 1 0 0 1 1 1 0 Bacterial conjugation TrbI-like protein HEAT_2 PF13646.1 EIE91473.1 - 3.7e-25 88.0 0.0 0.00012 22.3 0.0 7.6 4 3 2 6 6 6 5 HEAT repeats HEAT PF02985.17 EIE91473.1 - 3.6e-24 82.6 8.0 4.1e-05 23.3 0.0 11.2 12 0 0 12 12 11 4 HEAT repeat HEAT_EZ PF13513.1 EIE91473.1 - 5.1e-23 80.8 0.4 3.4e-07 30.5 0.0 9.3 9 1 3 12 12 10 4 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EIE91473.1 - 1e-11 45.0 5.0 0.00078 19.7 0.0 7.6 6 1 3 9 9 9 3 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 EIE91473.1 - 2.7e-11 43.2 1.3 0.11 11.8 0.0 7.6 5 2 2 7 7 7 2 CLASP N terminal IBN_N PF03810.14 EIE91473.1 - 1.9e-09 37.2 3.7 9.5e-09 35.0 0.6 3.9 4 0 0 4 4 4 1 Importin-beta N-terminal domain DUF3385 PF11865.3 EIE91473.1 - 8.5e-06 25.7 2.0 4.8 7.0 0.0 5.8 3 2 1 4 4 4 1 Domain of unknown function (DUF3385) ParcG PF10274.4 EIE91473.1 - 0.00018 21.4 2.5 0.0078 16.1 0.0 3.9 4 0 0 4 4 4 1 Parkin co-regulated protein DUF1546 PF07571.8 EIE91473.1 - 0.0015 18.5 0.3 0.31 11.1 0.1 3.5 2 1 1 3 3 3 1 Protein of unknown function (DUF1546) DUF1296 PF06972.6 EIE91473.1 - 0.0081 16.0 0.2 0.023 14.6 0.2 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1296) Myb_DNA-binding PF00249.26 EIE91473.1 - 0.0095 15.9 1.0 0.024 14.6 0.0 2.2 2 0 0 2 2 1 1 Myb-like DNA-binding domain Ipi1_N PF12333.3 EIE91473.1 - 0.015 15.2 1.3 4.4 7.3 0.0 4.9 5 1 1 6 6 6 0 Rix1 complex component involved in 60S ribosome maturation PNPOx_C PF10590.4 EIE91473.1 - 0.063 12.7 0.1 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Arm PF00514.18 EIE91473.1 - 0.11 12.3 9.7 32 4.5 0.0 6.2 5 1 1 6 6 6 0 Armadillo/beta-catenin-like repeat Ank_2 PF12796.2 EIE91475.1 - 1.7e-21 76.3 0.0 6e-14 52.1 0.0 2.6 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EIE91475.1 - 1.5e-16 60.4 0.2 2.1e-07 31.2 0.0 3.9 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 EIE91475.1 - 2.5e-11 42.7 0.1 0.0002 20.9 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 EIE91475.1 - 1.5e-08 34.0 0.5 0.015 15.4 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 EIE91475.1 - 8.2e-08 32.2 0.0 1.8e-06 27.9 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) zf-U1 PF06220.7 EIE91476.1 - 5.1e-22 77.1 3.4 6.7e-22 76.7 2.3 1.2 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_jaz PF12171.3 EIE91476.1 - 0.0087 16.1 3.7 0.019 15.1 2.6 1.6 1 1 0 1 1 1 1 Zinc-finger double-stranded RNA-binding AKAP95 PF04988.7 EIE91476.1 - 0.056 13.2 0.1 0.069 12.9 0.1 1.1 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) DUF2296 PF10058.4 EIE91477.1 - 1.3e-20 72.8 0.4 2.3e-20 72.0 0.3 1.4 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) DUF3810 PF12725.2 EIE91477.1 - 0.0024 16.8 1.0 0.0035 16.3 0.3 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3810) DUF2663 PF10864.3 EIE91477.1 - 0.0049 17.0 1.0 0.011 15.9 0.7 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2663) SMN PF06003.7 EIE91477.1 - 0.033 13.3 0.3 0.054 12.6 0.2 1.3 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) tRNA_anti-like PF12869.2 EIE91477.1 - 0.061 12.7 0.6 0.12 11.7 0.4 1.5 1 0 0 1 1 1 0 tRNA_anti-like SUR7 PF06687.7 EIE91478.1 - 0.00028 20.5 4.0 0.00028 20.5 2.8 2.0 1 1 1 2 2 2 1 SUR7/PalI family Shisa PF13908.1 EIE91478.1 - 0.0015 18.7 7.3 0.046 13.8 0.5 2.3 2 0 0 2 2 2 2 Wnt and FGF inhibitory regulator DUF3464 PF11947.3 EIE91478.1 - 0.77 9.2 2.6 2.3 7.6 1.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3464) Diphthamide_syn PF01866.12 EIE91479.1 - 2e-115 385.2 0.0 2.4e-115 385.0 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein HTH_psq PF05225.11 EIE91479.1 - 0.2 11.2 0.0 0.2 11.2 0.0 2.2 3 0 0 3 3 3 0 helix-turn-helix, Psq domain Spc7 PF08317.6 EIE91480.1 - 1.8e-05 23.6 20.8 1.8e-05 23.6 14.4 11.8 2 2 9 13 13 13 5 Spc7 kinetochore protein Reo_sigmaC PF04582.7 EIE91480.1 - 0.0065 15.6 2.2 0.0065 15.6 1.5 10.6 3 3 7 11 11 11 6 Reovirus sigma C capsid protein Myosin_tail_1 PF01576.14 EIE91480.1 - 0.57 7.8 276.3 0.0034 15.1 9.8 6.1 1 1 4 5 5 5 0 Myosin tail Eco57I PF07669.6 EIE91481.1 - 1.1e-05 25.7 0.0 2.7e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Eco57I restriction-modification methylase GnHR_trans PF12369.3 EIE91481.1 - 0.14 12.6 1.4 0.21 12.0 0.1 1.9 2 0 0 2 2 2 0 Gonadotropin hormone receptor transmembrane region SPRY PF00622.23 EIE91482.1 - 3.4e-21 75.6 0.0 5.3e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 SPRY domain PAP_assoc PF03828.14 EIE91483.1 - 6.3e-19 67.6 0.1 1.7e-18 66.3 0.0 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase SH3_9 PF14604.1 EIE91484.1 - 1.3e-11 43.8 0.0 2e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EIE91484.1 - 5.6e-06 25.6 0.0 9.3e-06 24.9 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EIE91484.1 - 0.00062 19.2 0.0 0.00088 18.7 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain Hid1 PF12722.2 EIE91485.1 - 0.5 7.9 10.6 0.63 7.6 7.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Pkinase PF00069.20 EIE91486.1 - 3.2e-44 151.0 0.0 4.8e-44 150.4 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE91486.1 - 1.1e-16 60.6 0.0 1.4e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE91486.1 - 1.4e-08 34.0 0.0 2e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EIE91486.1 - 9.1e-05 22.3 0.2 0.00013 21.7 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EIE91486.1 - 0.00019 20.8 0.3 0.00035 19.9 0.1 1.5 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.9 EIE91486.1 - 0.00031 19.8 0.4 0.00048 19.2 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EIE91486.1 - 0.048 13.2 0.7 0.099 12.2 0.5 1.5 1 1 0 1 1 1 0 Choline/ethanolamine kinase DUF2276 PF10040.4 EIE91486.1 - 0.11 12.7 0.0 0.16 12.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2276) PAS_9 PF13426.1 EIE91487.1 - 2.5e-10 40.6 0.1 0.015 15.6 0.0 3.6 3 0 0 3 3 3 3 PAS domain PAS PF00989.19 EIE91487.1 - 0.00036 20.2 0.1 3.8 7.3 0.0 4.1 3 1 1 4 4 4 2 PAS fold Helicase_C PF00271.26 EIE91490.1 - 1.4e-05 24.8 0.0 2.5e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HTH_22 PF13309.1 EIE91490.1 - 0.015 15.0 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 HTH domain Nuc_deoxyrib_tr PF05014.10 EIE91490.1 - 0.13 12.1 0.0 0.24 11.2 0.0 1.5 1 1 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase Polysacc_deac_1 PF01522.16 EIE91491.1 - 4.5e-30 103.8 0.1 9.3e-30 102.8 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 EIE91491.1 - 4.2e-05 22.6 0.0 6.1e-05 22.0 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 57 S_layer_N PF05123.7 EIE91491.1 - 0.053 13.1 0.1 2 7.9 0.0 2.1 2 0 0 2 2 2 0 S-layer like family, N-terminal region DUF1485 PF07364.7 EIE91491.1 - 0.13 11.4 0.1 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1485) zf-H2C2_2 PF13465.1 EIE91492.1 - 4.1e-20 70.9 12.8 2.5e-08 33.8 0.5 6.8 8 1 0 8 8 8 3 Zinc-finger double domain zf-C2H2 PF00096.21 EIE91492.1 - 4.6e-11 42.3 50.4 0.00044 20.4 0.3 7.4 8 0 0 8 8 7 5 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EIE91492.1 - 3.1e-09 36.7 8.4 0.00035 20.6 0.3 4.4 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EIE91492.1 - 1.8e-08 33.9 11.4 6.1e-05 22.7 0.2 4.9 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_4 PF13894.1 EIE91492.1 - 3.5e-05 23.8 46.7 0.00031 20.8 0.7 7.8 7 1 0 7 7 7 3 C2H2-type zinc finger zf-met PF12874.2 EIE91492.1 - 0.003 17.7 1.4 0.003 17.7 1.0 4.8 6 0 0 6 6 5 1 Zinc-finger of C2H2 type C1_4 PF07975.7 EIE91492.1 - 0.0053 16.7 4.7 0.0053 16.7 3.3 4.0 2 2 1 4 4 4 2 TFIIH C1-like domain Zn_Tnp_IS1 PF03811.8 EIE91492.1 - 0.04 13.4 4.3 4.7 6.7 0.4 3.1 2 0 0 2 2 2 0 InsA N-terminal domain XPA_N PF01286.13 EIE91492.1 - 0.12 12.0 8.8 5.7 6.7 0.2 3.9 4 0 0 4 4 4 0 XPA protein N-terminal zf-H2C2_5 PF13909.1 EIE91492.1 - 0.23 11.7 0.3 0.23 11.7 0.2 8.2 10 0 0 10 10 8 0 C2H2-type zinc-finger domain Zn-ribbon_8 PF09723.5 EIE91492.1 - 0.32 10.9 0.1 0.32 10.9 0.1 5.5 6 0 0 6 6 6 0 Zinc ribbon domain DUF2225 PF09986.4 EIE91492.1 - 2 7.8 8.4 2.6e+02 0.8 5.8 2.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-C2H2_2 PF12756.2 EIE91492.1 - 2.7 8.1 21.0 11 6.2 8.0 4.5 1 1 4 5 5 5 0 C2H2 type zinc-finger (2 copies) UQ_con PF00179.21 EIE91493.1 - 5.2e-27 93.9 0.1 6.2e-27 93.7 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EIE91493.1 - 0.032 14.1 0.1 0.043 13.7 0.1 1.3 1 0 0 1 1 1 0 RWD domain AAA PF00004.24 EIE91495.1 - 1.1e-53 180.9 0.1 5.1e-39 133.4 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EIE91495.1 - 1.3e-10 41.4 1.0 3.4e-06 27.0 0.1 3.6 3 0 0 3 3 3 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EIE91495.1 - 5.3e-10 39.5 2.4 0.00046 20.3 0.1 4.2 2 2 0 2 2 2 2 AAA domain CDC48_N PF02359.13 EIE91495.1 - 3.9e-09 36.3 0.0 1.2e-08 34.7 0.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_16 PF13191.1 EIE91495.1 - 2e-08 34.4 0.1 0.0064 16.4 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain RuvB_N PF05496.7 EIE91495.1 - 3.7e-08 32.7 0.2 0.0034 16.4 0.0 2.8 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 EIE91495.1 - 4.3e-08 32.2 1.1 0.0077 14.9 0.1 2.8 2 1 1 3 3 3 2 TIP49 C-terminus AAA_5 PF07728.9 EIE91495.1 - 7.4e-08 32.2 0.7 0.0011 18.6 0.0 3.5 4 0 0 4 4 3 2 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EIE91495.1 - 1e-07 32.8 0.0 0.0048 17.6 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EIE91495.1 - 1.2e-07 31.3 1.0 0.011 15.4 0.1 2.8 3 0 0 3 3 2 2 Part of AAA domain AAA_18 PF13238.1 EIE91495.1 - 2.6e-07 30.9 0.7 0.0037 17.5 0.0 3.9 3 1 1 4 4 3 2 AAA domain AAA_14 PF13173.1 EIE91495.1 - 2.7e-07 30.5 0.0 0.024 14.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 EIE91495.1 - 5e-07 29.3 0.1 0.034 13.5 0.0 2.9 3 0 0 3 3 3 2 IstB-like ATP binding protein NACHT PF05729.7 EIE91495.1 - 5.6e-07 29.3 1.0 0.019 14.6 0.0 3.6 3 1 0 3 3 3 2 NACHT domain Mg_chelatase PF01078.16 EIE91495.1 - 6e-07 28.8 0.2 0.0034 16.5 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI CDC48_2 PF02933.12 EIE91495.1 - 2.9e-06 26.8 2.1 2.9e-05 23.6 0.1 3.0 3 0 0 3 3 3 1 Cell division protein 48 (CDC48), domain 2 Sigma54_activat PF00158.21 EIE91495.1 - 5.1e-06 26.0 0.1 0.077 12.4 0.0 3.1 3 0 0 3 3 3 2 Sigma-54 interaction domain PhoH PF02562.11 EIE91495.1 - 5.2e-06 25.8 0.5 0.023 13.9 0.0 3.3 4 0 0 4 4 4 2 PhoH-like protein AAA_33 PF13671.1 EIE91495.1 - 5.8e-06 26.2 0.0 0.12 12.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 EIE91495.1 - 6.6e-06 26.2 0.0 0.022 14.9 0.0 3.0 3 0 0 3 3 2 1 RNA helicase ABC_tran PF00005.22 EIE91495.1 - 1.3e-05 25.4 0.4 0.32 11.2 0.0 3.5 3 1 0 3 3 2 2 ABC transporter AAA_24 PF13479.1 EIE91495.1 - 1.5e-05 24.7 0.5 0.044 13.3 0.1 2.8 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 EIE91495.1 - 1.8e-05 24.5 0.8 2.5 7.7 0.1 3.7 2 2 1 3 3 3 1 Archaeal ATPase KaiC PF06745.8 EIE91495.1 - 1.9e-05 23.9 0.2 0.012 14.7 0.0 2.9 3 0 0 3 3 2 1 KaiC AAA_25 PF13481.1 EIE91495.1 - 3.8e-05 23.1 5.7 0.063 12.6 0.1 3.9 2 2 1 3 3 3 2 AAA domain Zeta_toxin PF06414.7 EIE91495.1 - 6.3e-05 22.1 0.1 0.19 10.7 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin UPF0079 PF02367.12 EIE91495.1 - 9.3e-05 22.0 0.2 0.2 11.2 0.0 2.6 2 0 0 2 2 2 2 Uncharacterised P-loop hydrolase UPF0079 AAA_28 PF13521.1 EIE91495.1 - 0.0001 22.2 0.0 0.26 11.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 EIE91495.1 - 0.0001 21.9 0.1 0.17 11.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain KAP_NTPase PF07693.9 EIE91495.1 - 0.00035 19.6 0.0 1.3 7.8 0.0 3.1 2 1 1 3 3 3 1 KAP family P-loop domain Parvo_NS1 PF01057.12 EIE91495.1 - 0.00038 19.4 0.0 0.61 8.9 0.0 2.4 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.1 EIE91495.1 - 0.00047 20.2 0.6 1.2 9.1 0.0 3.8 3 1 1 4 4 3 1 Sigma-54 interaction domain DUF2075 PF09848.4 EIE91495.1 - 0.00084 18.4 0.1 0.3 10.0 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_3 PF07726.6 EIE91495.1 - 0.00085 18.9 0.0 0.076 12.6 0.0 3.0 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 EIE91495.1 - 0.0009 18.2 0.0 0.95 8.3 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein NB-ARC PF00931.17 EIE91495.1 - 0.0013 17.6 0.1 1.5 7.6 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain AAA_29 PF13555.1 EIE91495.1 - 0.0056 16.1 0.2 0.27 10.7 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain KTI12 PF08433.5 EIE91495.1 - 0.0084 15.3 0.1 0.23 10.6 0.0 2.3 2 0 0 2 2 2 1 Chromatin associated protein KTI12 DEAD PF00270.24 EIE91495.1 - 0.0085 15.6 1.0 9.1 5.7 0.2 4.0 2 2 1 4 4 4 0 DEAD/DEAH box helicase NTPase_1 PF03266.10 EIE91495.1 - 0.024 14.3 0.9 7 6.3 0.1 3.1 2 1 1 3 3 3 0 NTPase SKI PF01202.17 EIE91495.1 - 0.031 14.1 0.0 22 4.8 0.0 3.3 3 0 0 3 3 3 0 Shikimate kinase ATP-synt_ab PF00006.20 EIE91495.1 - 0.041 13.3 0.1 6.7 6.1 0.0 2.9 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain ResIII PF04851.10 EIE91495.1 - 0.045 13.5 0.7 15 5.3 0.1 3.0 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_10 PF12846.2 EIE91495.1 - 0.045 13.1 0.1 2.9 7.2 0.0 2.9 3 0 0 3 3 3 0 AAA-like domain AAA_11 PF13086.1 EIE91495.1 - 0.049 13.1 0.0 1 8.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain CPT PF07931.7 EIE91495.1 - 0.063 12.8 0.0 1.2 8.7 0.0 2.5 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein DAP3 PF10236.4 EIE91495.1 - 0.072 12.0 0.1 5.5 5.8 0.0 2.5 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 APS_kinase PF01583.15 EIE91495.1 - 0.097 12.3 0.1 5.1 6.7 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase IPT PF01745.11 EIE91495.1 - 0.1 11.7 0.4 3.9 6.5 0.0 2.7 3 0 0 3 3 3 0 Isopentenyl transferase cobW PF02492.14 EIE91495.1 - 0.11 11.9 2.4 3.4 7.0 0.1 2.9 2 1 1 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.17 EIE91495.1 - 0.17 11.2 1.6 9.1 5.6 0.1 2.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain RF-1 PF00472.15 EIE91497.1 - 5.5e-26 90.6 1.1 7.1e-26 90.2 0.7 1.1 1 0 0 1 1 1 1 RF-1 domain XRN_N PF03159.13 EIE91497.1 - 0.00073 19.0 2.1 0.48 9.7 0.0 2.1 2 0 0 2 2 2 2 XRN 5'-3' exonuclease N-terminus DUF2250 PF10007.4 EIE91497.1 - 0.0093 15.8 0.3 0.016 15.1 0.2 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) HMA PF00403.21 EIE91498.1 - 0.04 14.0 0.4 0.046 13.8 0.3 1.1 1 0 0 1 1 1 0 Heavy-metal-associated domain FpoO PF10621.4 EIE91498.1 - 0.13 12.3 0.1 0.14 12.2 0.0 1.1 1 0 0 1 1 1 0 F420H2 dehydrogenase subunit FpoO zf-H2C2_2 PF13465.1 EIE91501.1 - 2.8e-25 87.3 24.2 1.1e-07 31.7 0.1 5.9 5 1 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.21 EIE91501.1 - 1.5e-20 72.1 33.8 1.4e-06 28.2 0.9 5.4 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIE91501.1 - 5.7e-14 51.3 27.1 0.0017 18.5 0.5 4.9 5 0 0 5 5 5 4 C2H2-type zinc finger zf-TRAF PF02176.13 EIE91501.1 - 0.00072 19.8 9.8 0.2 12.0 0.3 3.3 1 1 2 3 3 3 3 TRAF-type zinc finger zf-C2H2_jaz PF12171.3 EIE91501.1 - 0.0032 17.5 14.3 2 8.6 0.0 5.1 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EIE91501.1 - 0.0092 16.1 10.9 1.4 9.2 0.1 4.8 5 0 0 5 5 5 2 Zinc-finger of C2H2 type Ogr_Delta PF04606.7 EIE91501.1 - 0.43 10.2 6.3 1.1 9.0 0.1 3.3 1 1 3 4 4 4 0 Ogr/Delta-like zinc finger zf-C2H2_6 PF13912.1 EIE91501.1 - 0.63 10.0 12.8 2.1 8.3 0.2 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger RPAP2_Rtr1 PF04181.8 EIE91501.1 - 3.5 7.7 8.9 72 3.5 3.9 3.4 1 1 1 2 2 2 0 Rtr1/RPAP2 family UPF0121 PF03661.8 EIE91502.1 - 4.6e-12 45.6 3.1 6.4e-12 45.1 2.2 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) Peptidase_M1 PF01433.15 EIE91503.1 - 7.1e-138 459.9 0.3 1.2e-137 459.1 0.2 1.4 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 EIE91503.1 - 2.6e-67 227.3 1.7 2.6e-67 227.3 1.2 1.9 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EIE91503.1 - 6.2e-19 68.3 0.5 1.8e-18 66.7 0.3 1.9 1 0 0 1 1 1 1 Peptidase MA superfamily Complex1_51K PF01512.12 EIE91504.1 - 6e-49 165.6 0.0 8.7e-49 165.1 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 EIE91504.1 - 1e-19 69.3 0.7 2e-19 68.4 0.5 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 EIE91504.1 - 1.2e-08 34.7 0.0 2.6e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 SLBB domain CK_II_beta PF01214.13 EIE91505.1 - 5.8e-61 205.2 0.1 6.9e-61 204.9 0.0 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Dynactin_p62 PF05502.8 EIE91505.1 - 1.3 7.7 3.8 1.7 7.2 2.6 1.1 1 0 0 1 1 1 0 Dynactin p62 family Dynamin_N PF00350.18 EIE91506.1 - 7.8e-44 149.4 0.0 7.8e-44 149.4 0.0 2.7 3 0 0 3 3 3 1 Dynamin family Dynamin_M PF01031.15 EIE91506.1 - 1.7e-16 59.8 2.2 7.4e-14 51.2 0.1 2.7 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.18 EIE91506.1 - 3.1e-05 23.8 0.0 0.00029 20.7 0.0 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EIE91506.1 - 0.0015 19.0 0.2 0.0083 16.6 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein AAA_21 PF13304.1 EIE91506.1 - 0.027 14.4 0.4 0.19 11.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EIE91506.1 - 0.096 12.2 0.0 0.57 9.7 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain RskA PF10099.4 EIE91506.1 - 0.13 12.0 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA ABC_tran PF00005.22 EIE91506.1 - 1.8 8.8 0.0 1.8 8.8 0.0 3.8 4 1 0 4 4 4 0 ABC transporter Ribosomal_L1 PF00687.16 EIE91507.1 - 4.7e-51 173.2 1.6 5.6e-51 172.9 1.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Metallophos PF00149.23 EIE91508.1 - 4e-44 150.4 0.4 4.9e-44 150.1 0.3 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase cwf21 PF08312.7 EIE91508.1 - 0.032 14.0 0.4 0.056 13.3 0.3 1.3 1 0 0 1 1 1 0 cwf21 domain Proteasome PF00227.21 EIE91509.1 - 6.9e-47 159.1 0.0 7.9e-47 159.0 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit EF-hand_1 PF00036.27 EIE91510.1 - 1.5e-24 83.3 13.3 2.1e-08 32.8 0.6 4.4 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 EIE91510.1 - 3.5e-23 81.5 8.3 6.7e-15 54.9 1.4 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EIE91510.1 - 1.7e-20 72.3 11.9 1.2e-07 31.1 1.3 4.1 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 EIE91510.1 - 9.4e-19 65.5 7.7 1.5e-07 30.7 0.3 4.4 3 1 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.1 EIE91510.1 - 2.9e-15 54.8 13.4 2.5e-05 23.4 0.2 4.7 4 1 1 5 5 5 3 EF hand SPARC_Ca_bdg PF10591.4 EIE91510.1 - 3.4e-05 23.8 3.9 0.0015 18.5 0.3 2.3 1 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EIE91510.1 - 0.0024 17.5 6.9 0.89 9.3 0.8 3.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 EIE91510.1 - 0.019 14.8 0.1 5.5 6.9 0.0 2.7 2 1 0 2 2 2 0 EF-hand domain DUF87 PF01935.12 EIE91510.1 - 0.06 13.1 0.1 0.068 12.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF87 MecA_N PF05223.6 EIE91510.1 - 0.14 12.2 0.6 14 5.8 0.0 2.2 1 1 1 2 2 2 0 NTF2-like N-terminal transpeptidase domain EF-hand_10 PF14788.1 EIE91510.1 - 0.71 9.5 4.2 1.7 8.3 0.1 3.1 3 1 0 3 3 3 0 EF hand EF-hand_7 PF13499.1 EIE91511.1 - 9e-20 70.5 8.9 5.8e-15 55.1 1.9 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EIE91511.1 - 5.3e-19 66.0 13.2 3.3e-08 32.2 1.4 4.2 4 1 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 EIE91511.1 - 9.6e-18 62.4 10.6 1e-06 28.0 0.2 4.3 3 1 1 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EIE91511.1 - 7.5e-13 47.1 7.0 4.3e-06 25.8 0.6 3.7 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 EIE91511.1 - 1e-12 47.4 11.8 3.4e-08 32.9 0.6 4.2 3 2 1 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.2 EIE91511.1 - 9.7e-09 34.9 6.0 4.8e-05 23.0 0.6 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EIE91511.1 - 2.5e-05 24.2 2.2 0.001 19.0 0.4 2.3 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EFhand_Ca_insen PF08726.5 EIE91511.1 - 0.0078 16.1 1.3 0.057 13.3 0.1 2.1 2 0 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_10 PF14788.1 EIE91511.1 - 0.029 14.0 0.8 0.078 12.6 0.5 1.8 1 0 0 1 1 1 0 EF hand TerB PF05099.8 EIE91511.1 - 0.048 13.3 0.4 3.2 7.4 0.0 2.7 2 1 0 2 2 2 0 Tellurite resistance protein TerB S_100 PF01023.14 EIE91511.1 - 0.093 12.0 3.3 3.1 7.1 0.1 3.4 3 0 0 3 3 3 0 S-100/ICaBP type calcium binding domain EF-hand_like PF09279.6 EIE91511.1 - 0.11 12.5 1.5 2.5 8.1 0.1 2.3 2 0 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like LAGLIDADG_3 PF14528.1 EIE91511.1 - 0.11 12.7 0.3 0.26 11.5 0.2 1.6 1 0 0 1 1 1 0 LAGLIDADG-like domain Dockerin_1 PF00404.13 EIE91511.1 - 3.7 7.4 4.7 11 5.9 0.3 2.9 3 0 0 3 3 3 0 Dockerin type I repeat Claudin_2 PF13903.1 EIE91512.1 - 0.001 18.7 9.6 0.0099 15.5 4.7 2.6 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction UbiA PF01040.13 EIE91512.1 - 0.71 9.0 8.6 0.098 11.8 3.1 1.6 2 0 0 2 2 2 0 UbiA prenyltransferase family SID-1_RNA_chan PF13965.1 EIE91512.1 - 1.5 6.9 12.1 0.017 13.3 2.4 1.9 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 Rad51 PF08423.6 EIE91513.1 - 2.4e-21 75.8 0.0 3.2e-21 75.3 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EIE91513.1 - 1.1e-07 31.4 0.0 1.6e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 EIE91513.1 - 5.9e-07 28.8 0.0 8.1e-07 28.3 0.0 1.3 1 0 0 1 1 1 1 KaiC RecA PF00154.16 EIE91513.1 - 2e-05 23.8 0.2 2.7e-05 23.3 0.1 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein PAXNEB PF05625.6 EIE91513.1 - 0.013 14.3 0.9 0.021 13.6 0.6 1.2 1 0 0 1 1 1 0 PAXNEB protein PDGF_N PF04692.8 EIE91513.1 - 0.19 12.2 1.1 0.27 11.7 0.1 1.7 2 0 0 2 2 2 0 Platelet-derived growth factor, N terminal region PRP38 PF03371.10 EIE91514.1 - 1.6e-26 92.9 0.1 2.7e-26 92.2 0.0 1.3 1 0 0 1 1 1 1 PRP38 family SET PF00856.23 EIE91515.1 - 0.0003 21.1 0.0 0.00052 20.3 0.0 1.3 1 0 0 1 1 1 1 SET domain Mito_fiss_reg PF05308.6 EIE91516.1 - 0.069 12.5 0.5 0.076 12.3 0.4 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator Mak16 PF04874.9 EIE91518.1 - 0.049 13.7 9.0 0.051 13.6 6.3 1.0 1 0 0 1 1 1 0 Mak16 protein C-terminal region SIC PF03482.8 EIE91518.1 - 0.12 11.9 4.4 0.12 11.9 3.1 1.0 1 0 0 1 1 1 0 sic protein Sigma70_ner PF04546.8 EIE91518.1 - 3.5 7.1 8.7 3.7 7.0 6.0 1.0 1 0 0 1 1 1 0 Sigma-70, non-essential region Nucleoplasmin PF03066.10 EIE91518.1 - 5.4 6.5 14.8 5.7 6.4 10.2 1.1 1 0 0 1 1 1 0 Nucleoplasmin CENP-B_dimeris PF09026.5 EIE91518.1 - 6.3 7.0 15.6 7.6 6.8 10.8 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF4611 PF15387.1 EIE91518.1 - 7.3 6.8 9.7 8.2 6.6 6.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) BSP_II PF05432.6 EIE91518.1 - 9.4 5.4 12.9 8.8 5.5 9.0 1.0 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) PI3K_1B_p101 PF10486.4 EIE91518.1 - 10 3.5 6.9 9.2 3.6 4.8 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Chitin_synth_1 PF01644.12 EIE91519.1 - 6.2e-85 282.9 0.1 9.3e-85 282.4 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EIE91519.1 - 1.4e-31 107.9 0.2 2.7e-31 107.0 0.1 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EIE91519.1 - 1.9e-22 79.3 1.1 2.9e-18 65.5 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 EIE91519.1 - 1.1e-07 31.7 8.6 5.9e-07 29.3 6.0 2.3 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EIE91519.1 - 1.7e-06 28.0 0.0 3.2e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 NUFIP1 PF10453.4 EIE91520.1 - 5e-14 51.5 1.8 5e-14 51.5 1.2 1.7 2 0 0 2 2 2 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-H2C2_5 PF13909.1 EIE91520.1 - 0.87 9.9 7.6 0.11 12.7 2.0 2.1 2 0 0 2 2 2 0 C2H2-type zinc-finger domain DDE_3 PF13358.1 EIE91521.1 - 2.3e-10 40.4 0.0 3e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Rrp15p PF07890.7 EIE91522.1 - 0.14 12.2 3.2 0.13 12.2 2.2 1.0 1 0 0 1 1 1 0 Rrp15p Glyco_hydro_97 PF10566.4 EIE91525.1 - 0.011 14.8 0.3 0.013 14.5 0.2 1.1 1 0 0 1 1 1 0 Glycoside hydrolase 97 DUF2681 PF10883.3 EIE91525.1 - 1.2 9.4 5.3 0.12 12.5 0.8 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) IMS PF00817.15 EIE91526.1 - 0.1 12.3 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 impB/mucB/samB family zf-TFIIB PF13453.1 EIE91528.1 - 0.28 10.4 8.4 0.34 10.1 2.0 2.7 2 0 0 2 2 2 0 Transcription factor zinc-finger UVR PF02151.14 EIE91528.1 - 1.5 8.4 13.4 1 8.9 1.1 3.0 3 0 0 3 3 3 0 UvrB/uvrC motif Thiolase_N PF00108.18 EIE91530.1 - 8.5e-88 293.7 0.0 1.7e-87 292.7 0.0 1.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EIE91530.1 - 1.2e-46 157.0 1.3 2.2e-46 156.2 0.3 1.9 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EIE91530.1 - 3.2e-07 30.1 0.6 7.2e-07 28.9 0.1 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain TPR_1 PF00515.23 EIE91532.1 - 5.6e-16 57.3 4.7 4.1e-07 29.3 0.0 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat PB1 PF00564.19 EIE91532.1 - 3.2e-15 55.5 0.5 7.1e-15 54.4 0.4 1.6 1 0 0 1 1 1 1 PB1 domain TPR_11 PF13414.1 EIE91532.1 - 4.2e-13 48.7 6.2 1.6e-11 43.6 0.3 3.0 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 EIE91532.1 - 3.9e-12 45.1 2.8 6.2e-05 22.6 0.0 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 EIE91532.1 - 1.2e-08 34.0 1.4 0.00023 20.7 0.1 4.2 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 EIE91532.1 - 2.9e-07 30.1 1.0 0.001 19.0 0.1 4.0 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EIE91532.1 - 5.3e-07 29.4 0.9 1.8e-06 27.7 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 EIE91532.1 - 9.7e-07 29.3 1.1 0.00037 21.0 0.2 2.7 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 EIE91532.1 - 3.5e-05 23.9 3.0 1.8 9.1 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.1 EIE91532.1 - 0.00011 21.9 0.7 0.3 10.9 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EIE91532.1 - 0.0076 16.7 3.1 0.036 14.7 0.0 3.3 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EIE91532.1 - 0.018 15.3 0.2 0.063 13.6 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat Pkinase PF00069.20 EIE91533.1 - 6.5e-58 195.9 0.0 8.5e-58 195.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE91533.1 - 1.9e-27 95.9 0.0 2.5e-27 95.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE91533.1 - 6.6e-05 22.0 0.0 9.7e-05 21.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EIE91533.1 - 0.087 12.5 0.1 0.37 10.4 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.17 EIE91533.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 RIO1 family TMEM164 PF14808.1 EIE91534.1 - 6.8e-11 41.8 0.0 8.5e-11 41.5 0.0 1.1 1 0 0 1 1 1 1 TMEM164 family Radical_SAM PF04055.16 EIE91535.1 - 6.8e-28 97.9 0.0 1.4e-27 96.8 0.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily Wyosine_form PF08608.7 EIE91535.1 - 5.4e-23 80.8 0.0 1.9e-22 79.1 0.0 2.0 1 0 0 1 1 1 1 Wyosine base formation Flavodoxin_1 PF00258.20 EIE91535.1 - 5e-21 75.1 0.0 1.2e-20 73.9 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_3 PF12641.2 EIE91535.1 - 0.0063 15.9 1.9 0.11 11.8 0.0 2.4 2 0 0 2 2 2 1 Flavodoxin domain Flavodoxin_NdrI PF07972.6 EIE91535.1 - 0.0074 16.2 0.0 0.023 14.6 0.0 1.8 1 1 0 1 1 1 1 NrdI Flavodoxin like DUF1510 PF07423.6 EIE91535.1 - 0.11 11.8 5.3 0.18 11.1 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Urm1 PF09138.6 EIE91536.1 - 2.8e-36 123.5 0.2 3.1e-36 123.3 0.1 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 EIE91536.1 - 0.00017 21.9 0.0 0.0002 21.6 0.0 1.2 1 0 0 1 1 1 1 ThiS family Glu_synthase PF01645.12 EIE91537.1 - 4.6e-156 519.3 0.0 7.2e-156 518.7 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase GATase_2 PF00310.16 EIE91537.1 - 1.2e-133 445.3 0.0 8e-133 442.5 0.0 2.1 1 1 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 EIE91537.1 - 1.2e-118 395.5 0.0 1.8e-118 395.0 0.0 1.2 1 0 0 1 1 1 1 Glutamate synthase central domain GXGXG PF01493.14 EIE91537.1 - 4.1e-66 221.8 2.1 7.4e-66 221.0 1.5 1.4 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.1 EIE91537.1 - 5.7e-24 83.8 0.2 1.3e-23 82.7 0.1 1.6 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 EIE91537.1 - 6e-18 65.4 0.0 2e-17 63.7 0.0 2.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EIE91537.1 - 2.2e-11 44.2 0.1 0.0001 22.4 0.1 2.7 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIE91537.1 - 1.5e-07 31.3 0.0 4.4e-07 29.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EIE91537.1 - 6.5e-06 26.4 0.2 0.0019 18.5 0.0 2.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIE91537.1 - 0.0001 20.9 0.2 0.0001 20.9 0.1 2.0 3 0 0 3 3 3 1 HI0933-like protein DAO PF01266.19 EIE91537.1 - 0.00012 21.1 0.1 0.0019 17.1 0.0 2.8 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EIE91537.1 - 0.00057 18.8 0.1 0.004 16.0 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.1 EIE91537.1 - 0.00069 19.8 0.7 0.34 11.1 0.0 3.0 3 0 0 3 3 2 1 Putative NAD(P)-binding Amino_oxidase PF01593.19 EIE91537.1 - 0.00088 18.4 0.0 0.0017 17.5 0.0 1.5 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Thi4 PF01946.12 EIE91537.1 - 0.0046 16.0 0.1 0.058 12.4 0.0 2.3 2 0 0 2 2 2 1 Thi4 family AlaDh_PNT_C PF01262.16 EIE91537.1 - 0.0054 16.3 0.0 0.023 14.2 0.0 2.0 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.14 EIE91537.1 - 0.015 14.3 0.0 0.028 13.4 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.2 EIE91537.1 - 0.025 13.6 0.0 0.042 12.9 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_2 PF03446.10 EIE91537.1 - 0.026 14.3 0.1 0.094 12.5 0.1 2.0 2 0 0 2 2 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.18 EIE91537.1 - 0.027 14.1 0.0 0.062 13.0 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DJ-1_PfpI PF01965.19 EIE91537.1 - 0.028 13.8 0.2 0.67 9.4 0.0 2.4 1 1 0 2 2 2 0 DJ-1/PfpI family Shikimate_DH PF01488.15 EIE91537.1 - 0.032 14.3 0.3 7.4 6.6 0.0 2.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.1 EIE91537.1 - 0.054 13.2 0.0 0.32 10.7 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding GIDA PF01134.17 EIE91537.1 - 0.059 12.2 0.4 0.61 8.8 0.1 2.4 2 1 0 2 2 2 0 Glucose inhibited division protein A 2-Hacid_dh_C PF02826.14 EIE91537.1 - 0.093 11.8 0.0 0.65 9.1 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FMN_dh PF01070.13 EIE91537.1 - 0.1 11.4 1.6 0.29 9.9 0.9 1.8 2 0 0 2 2 2 0 FMN-dependent dehydrogenase UDPG_MGDP_dh_N PF03721.9 EIE91537.1 - 0.13 11.6 0.0 0.37 10.1 0.0 1.8 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain STE3 PF02076.10 EIE91537.1 - 2 7.4 4.8 3.5 6.6 3.4 1.3 1 0 0 1 1 1 0 Pheromone A receptor C2 PF00168.25 EIE91538.1 - 2.3e-16 59.4 0.0 6.1e-16 58.0 0.0 1.8 1 0 0 1 1 1 1 C2 domain Membr_traf_MHD PF10540.4 EIE91538.1 - 5.2e-15 55.4 0.1 1.7e-14 53.8 0.1 2.0 1 0 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain DUF810 PF05664.6 EIE91538.1 - 4.8e-09 35.0 4.2 1.2e-07 30.4 0.0 3.4 3 1 0 4 4 4 2 Protein of unknown function (DUF810) Clat_adaptor_s PF01217.15 EIE91539.1 - 3.4e-38 130.5 6.2 1.3e-34 118.8 4.3 2.0 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Septin PF00735.13 EIE91540.1 - 3.9e-57 193.4 3.5 5.8e-37 127.2 0.6 2.9 1 1 1 2 2 2 2 Septin MMR_HSR1 PF01926.18 EIE91540.1 - 1.4e-06 28.2 0.3 3.3e-06 27.0 0.2 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EIE91540.1 - 8.2e-06 25.7 2.3 0.12 12.1 0.1 3.5 2 1 1 3 3 3 2 Dynamin family GTP_EFTU PF00009.22 EIE91540.1 - 1.1e-05 24.9 0.8 0.002 17.5 0.2 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MobB PF03205.9 EIE91540.1 - 6.2e-05 22.7 0.3 0.00037 20.1 0.0 2.2 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 EIE91540.1 - 0.00028 21.3 0.2 0.0011 19.4 0.1 2.1 1 1 0 1 1 1 1 Miro-like protein AAA_16 PF13191.1 EIE91540.1 - 0.00035 20.6 0.0 0.00056 19.9 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 EIE91540.1 - 0.00042 20.2 0.0 0.00089 19.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 EIE91540.1 - 0.00076 19.0 0.0 0.0015 18.0 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family ABC_tran PF00005.22 EIE91540.1 - 0.0011 19.2 0.2 0.0064 16.7 0.1 2.4 1 1 0 1 1 1 1 ABC transporter SRPRB PF09439.5 EIE91540.1 - 0.004 16.3 1.7 0.15 11.2 0.2 2.5 1 1 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_24 PF13479.1 EIE91540.1 - 0.0049 16.4 0.1 0.045 13.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EIE91540.1 - 0.0086 15.0 0.1 0.021 13.7 0.1 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein Arch_ATPase PF01637.13 EIE91540.1 - 0.0096 15.6 1.3 0.015 14.9 0.1 1.9 2 0 0 2 2 2 1 Archaeal ATPase DUF258 PF03193.11 EIE91540.1 - 0.011 14.9 2.9 0.063 12.4 0.4 2.9 2 1 0 2 2 2 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 EIE91540.1 - 0.014 15.5 0.1 0.035 14.2 0.1 1.9 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.8 EIE91540.1 - 0.018 13.9 0.1 0.085 11.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF815) PRK PF00485.13 EIE91540.1 - 0.023 14.2 0.2 0.056 12.9 0.1 1.8 2 0 0 2 2 1 0 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.1 EIE91540.1 - 0.023 15.5 0.1 0.1 13.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 EIE91540.1 - 0.026 14.0 0.9 0.38 10.2 0.1 2.9 1 1 2 3 3 3 0 Conserved hypothetical ATP binding protein AAA_21 PF13304.1 EIE91540.1 - 0.029 14.3 0.9 0.11 12.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 EIE91540.1 - 0.035 13.6 0.5 0.36 10.3 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA PF00004.24 EIE91540.1 - 0.05 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EIE91540.1 - 0.05 13.4 1.0 0.082 12.8 0.0 1.9 2 0 0 2 2 1 0 AAA domain NACHT PF05729.7 EIE91540.1 - 0.058 13.0 0.1 0.21 11.2 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA_10 PF12846.2 EIE91540.1 - 0.072 12.5 0.1 0.15 11.4 0.1 1.6 1 1 0 1 1 1 0 AAA-like domain AAA_5 PF07728.9 EIE91540.1 - 0.074 12.7 0.0 0.15 11.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 EIE91540.1 - 0.22 11.7 0.0 0.22 11.7 0.0 2.2 3 0 0 3 3 1 0 RNA helicase PduV-EutP PF10662.4 EIE91540.1 - 0.29 10.6 3.3 2.5 7.5 1.3 2.9 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 EIE91540.1 - 0.4 10.0 0.1 0.4 10.0 0.0 3.0 3 2 1 4 4 3 0 CobW/HypB/UreG, nucleotide-binding domain Glyco_transf_49 PF13896.1 EIE91542.1 - 2.3e-45 155.0 0.2 2.4e-37 128.7 0.1 2.1 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glyco_tranf_2_2 PF10111.4 EIE91542.1 - 0.0031 16.6 0.0 0.0056 15.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EIE91542.1 - 0.012 15.2 0.1 0.047 13.3 0.1 2.1 1 1 0 1 1 1 0 Glycosyl transferase family 2 Mob1_phocein PF03637.12 EIE91543.1 - 0.026 14.2 0.1 0.032 13.8 0.1 1.1 1 0 0 1 1 1 0 Mob1/phocein family CRM1_C PF08767.6 EIE91544.1 - 4.3e-127 423.4 1.3 4.3e-127 423.4 0.9 3.8 3 2 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.7 EIE91544.1 - 8e-22 77.7 10.1 7.3e-13 48.6 0.5 5.4 4 2 1 5 5 5 2 Exportin 1-like protein IBN_N PF03810.14 EIE91544.1 - 1.1e-11 44.4 1.8 2.6e-11 43.2 0.3 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain W2 PF02020.13 EIE91545.1 - 4.7e-18 64.9 1.8 1.6e-17 63.1 1.2 2.0 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon PI3Ka PF00613.15 EIE91545.1 - 0.022 13.9 0.5 0.043 12.9 0.1 1.8 2 0 0 2 2 2 0 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF445 PF04286.7 EIE91545.1 - 0.031 13.8 0.2 0.081 12.4 0.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF445) DUF4070 PF13282.1 EIE91545.1 - 0.066 12.7 0.2 1.9 8.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4070) PCI PF01399.22 EIE91545.1 - 0.37 11.1 4.6 4.5 7.6 0.1 3.7 3 1 1 4 4 4 0 PCI domain Adeno_E3_CR2 PF02439.10 EIE91546.1 - 0.00015 21.2 0.2 0.00019 20.8 0.2 1.2 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 SPAN-X PF07458.7 EIE91546.1 - 0.027 14.6 0.0 0.031 14.4 0.0 1.1 1 0 0 1 1 1 0 Sperm protein associated with nucleus, mapped to X chromosome FAR1 PF03101.10 EIE91548.1 - 1.5e-05 25.3 0.1 3.4e-05 24.2 0.1 1.5 1 0 0 1 1 1 1 FAR1 DNA-binding domain WD40 PF00400.27 EIE91549.1 - 2.5e-28 96.8 3.7 3.5e-06 26.6 0.0 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 EIE91549.1 - 0.00045 19.1 0.3 0.00081 18.3 0.2 1.4 1 0 0 1 1 1 1 Coatomer WD associated region Nup160 PF11715.3 EIE91549.1 - 0.011 13.9 0.3 2.1 6.3 0.0 2.8 1 1 2 3 3 3 0 Nucleoporin Nup120/160 Pyr_redox_2 PF07992.9 EIE91550.1 - 1.7e-22 80.3 0.0 2.6e-22 79.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EIE91550.1 - 1.4e-15 57.4 0.0 3.3e-11 43.4 0.0 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_7 PF13499.1 EIE91550.1 - 4.4e-11 42.7 0.8 0.00023 21.2 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EIE91550.1 - 2.9e-10 38.6 7.8 2.8e-05 23.1 1.4 3.3 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 EIE91550.1 - 4.6e-08 32.2 3.8 0.0032 17.2 0.1 2.9 2 0 0 2 2 2 2 EF-hand domain Pyr_redox_3 PF13738.1 EIE91550.1 - 1.5e-06 28.4 0.0 1.5 8.8 0.0 3.9 4 0 0 4 4 4 3 Pyridine nucleotide-disulphide oxidoreductase EF-hand_5 PF13202.1 EIE91550.1 - 1.9e-06 26.9 7.9 8.2e-05 21.7 1.4 3.4 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 EIE91550.1 - 5e-06 26.0 2.4 8e-05 22.1 1.0 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_10 PF14788.1 EIE91550.1 - 0.0012 18.4 1.8 0.15 11.7 0.0 3.1 3 0 0 3 3 3 1 EF hand EF-hand_4 PF12763.2 EIE91550.1 - 0.0028 17.3 0.9 0.062 13.0 0.3 2.5 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand NAD_binding_8 PF13450.1 EIE91550.1 - 0.085 12.9 0.0 6.5 6.8 0.0 3.4 4 0 0 4 4 4 0 NAD(P)-binding Rossmann-like domain FlaC_arch PF05377.6 EIE91551.1 - 0.018 14.9 3.0 0.063 13.1 2.1 2.0 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF2353 PF09789.4 EIE91551.1 - 0.04 13.1 10.2 0.04 13.1 3.1 1.9 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) DUF1975 PF09318.5 EIE91551.1 - 0.095 12.2 10.6 0.18 11.4 7.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1975) Tweety PF04906.8 EIE91551.1 - 0.19 10.1 1.1 0.28 9.5 0.5 1.4 1 1 0 1 1 1 0 Tweety FliJ PF02050.11 EIE91551.1 - 0.48 10.4 6.1 0.24 11.4 2.4 1.8 2 0 0 2 2 2 0 Flagellar FliJ protein Methyltrn_RNA_4 PF09936.4 EIE91551.1 - 4.9 6.6 6.9 47 3.4 0.0 3.0 3 0 0 3 3 3 0 SAM-dependent RNA methyltransferase Stc1 PF12898.2 EIE91552.1 - 2.2e-19 69.2 19.4 3.2e-16 59.1 10.6 2.0 1 1 1 2 2 2 2 Stc1 domain zf-CHY PF05495.7 EIE91552.1 - 0.3 11.2 13.4 23 5.2 6.7 3.1 1 1 1 2 2 2 0 CHY zinc finger Mut7-C PF01927.11 EIE91552.1 - 0.78 9.7 8.7 4.9 7.1 1.2 2.2 1 1 1 2 2 2 0 Mut7-C RNAse domain SIR2 PF02146.12 EIE91552.1 - 2.2 7.9 7.9 6.2 6.5 1.3 2.2 1 1 0 2 2 2 0 Sir2 family FYVE_2 PF02318.11 EIE91552.1 - 3.1 7.7 10.6 1.6 8.6 3.7 2.2 1 1 1 2 2 2 0 FYVE-type zinc finger DUF3133 PF11331.3 EIE91552.1 - 3.1 7.4 7.0 3.1 7.4 2.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3133) zf-C3HC4_3 PF13920.1 EIE91552.1 - 4.1 7.1 16.3 0.91 9.2 3.0 3.0 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIE91552.1 - 8.2 6.2 13.0 13 5.5 3.4 3.0 3 0 0 3 3 3 0 zinc-RING finger domain DUF3330 PF11809.3 EIE91552.1 - 8.5 6.3 14.3 14 5.6 0.3 4.0 2 1 2 4 4 4 0 Domain of unknown function (DUF3330) zinc-ribbons_6 PF07191.7 EIE91552.1 - 9.3 6.1 12.6 0.44 10.3 2.0 2.7 2 1 1 3 3 3 0 zinc-ribbons zf-H2C2_2 PF13465.1 EIE91552.1 - 9.9 6.6 12.2 98 3.5 0.0 4.1 3 1 0 3 3 3 0 Zinc-finger double domain Pkinase PF00069.20 EIE91553.1 - 1.9e-73 246.8 0.0 2.1e-73 246.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE91553.1 - 4.6e-32 111.1 0.0 7.6e-32 110.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Seadorna_VP7 PF07387.6 EIE91553.1 - 0.01 14.6 0.1 0.016 14.0 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Kinase-like PF14531.1 EIE91553.1 - 0.033 13.1 0.0 0.1 11.5 0.0 1.6 1 1 0 2 2 2 0 Kinase-like DELLA PF12041.3 EIE91553.1 - 0.11 12.1 0.1 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator DELLA protein N terminal APH PF01636.18 EIE91553.1 - 0.15 11.7 0.3 0.24 11.1 0.2 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Vac_Fusion PF02346.11 EIE91554.1 - 0.094 12.1 0.2 0.18 11.2 0.1 1.4 1 0 0 1 1 1 0 Chordopoxvirus fusion protein PhyH PF05721.8 EIE91555.1 - 5.5e-14 52.6 0.0 7.7e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Peptidase_C14 PF00656.17 EIE91556.1 - 3.3e-64 216.9 0.2 4e-64 216.6 0.2 1.0 1 0 0 1 1 1 1 Caspase domain HLH PF00010.21 EIE91557.1 - 3.7e-06 26.5 0.0 8e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DDE_3 PF13358.1 EIE91558.1 - 0.00084 19.1 0.0 0.0015 18.3 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 EIE91558.1 - 0.068 13.3 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn helix DDE_3 PF13358.1 EIE91559.1 - 0.00075 19.2 0.0 0.0013 18.4 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease RRM_1 PF00076.17 EIE91560.1 - 1.4e-15 56.6 0.0 1.1e-11 44.1 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE91560.1 - 7.8e-09 35.3 0.0 1e-07 31.8 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE91560.1 - 3.2e-05 23.6 0.0 0.009 15.8 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DDE_3 PF13358.1 EIE91564.1 - 4.5e-09 36.2 0.0 5.2e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Kringle PF00051.13 EIE91564.1 - 0.1 12.6 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Kringle domain AA_permease_2 PF13520.1 EIE91565.1 - 9.8e-46 156.1 33.9 8.2e-41 139.9 11.0 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.16 EIE91565.1 - 3.6e-20 71.7 21.7 1.6e-19 69.6 7.9 2.0 2 0 0 2 2 2 2 Amino acid permease DUF754 PF05449.6 EIE91565.1 - 0.29 11.1 4.4 0.93 9.5 0.9 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF754) PH PF00169.24 EIE91566.1 - 1.3e-07 31.7 0.9 4.6e-07 29.9 0.0 2.4 2 1 0 2 2 2 1 PH domain Metallophos PF00149.23 EIE91567.1 - 8.1e-46 155.9 0.2 1e-45 155.6 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Nucleos_tra2_C PF07662.8 EIE91568.1 - 1.1e-63 214.5 8.1 1.1e-63 214.5 5.6 2.1 3 1 0 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 EIE91568.1 - 5.7e-21 74.6 9.6 5.7e-21 74.6 6.6 3.4 4 0 0 4 4 4 1 Na+ dependent nucleoside transporter N-terminus Sec2p PF06428.6 EIE91569.1 - 2.7e-10 39.9 13.9 2.7e-10 39.9 9.6 2.5 1 1 1 2 2 2 1 GDP/GTP exchange factor Sec2p DNA_alkylation PF08713.6 EIE91569.1 - 6.2e-05 22.6 3.9 0.0001 21.9 0.0 2.6 3 0 0 3 3 3 1 DNA alkylation repair enzyme APG6 PF04111.7 EIE91569.1 - 0.013 14.5 20.2 0.024 13.6 14.0 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3584 PF12128.3 EIE91569.1 - 0.031 11.6 16.5 0.044 11.1 11.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF745 PF05335.8 EIE91569.1 - 0.51 9.8 12.5 0.6 9.6 7.8 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Fib_alpha PF08702.5 EIE91569.1 - 0.91 9.6 18.0 0.3 11.2 5.1 3.1 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Laminin_I PF06008.9 EIE91569.1 - 1.5 8.0 18.7 4.4 6.5 13.0 1.7 1 1 0 1 1 1 0 Laminin Domain I CENP-Q PF13094.1 EIE91569.1 - 1.6 8.7 17.1 9.1 6.2 11.9 2.1 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Trypan_glycop PF00913.14 EIE91569.1 - 1.8 7.3 10.5 2.6 6.8 7.3 1.1 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein (A-type) Atg14 PF10186.4 EIE91569.1 - 3.2 6.6 16.7 5.4 5.8 11.0 1.8 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF948 PF06103.6 EIE91569.1 - 4.8 7.1 12.7 1.1 9.1 2.0 3.3 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) Glyco_tranf_2_3 PF13641.1 EIE91570.1 - 2.6e-19 69.9 0.0 3.6e-19 69.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EIE91570.1 - 1.4e-07 31.3 0.0 2.1e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EIE91570.1 - 0.00012 21.4 0.0 0.00023 20.4 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.4 EIE91570.1 - 0.15 11.0 0.1 0.24 10.4 0.1 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Pkinase PF00069.20 EIE91571.1 - 2.3e-57 194.1 0.0 1.3e-56 191.6 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE91571.1 - 4e-25 88.3 0.0 1.3e-24 86.7 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE91571.1 - 1.1e-05 24.5 0.0 2.5e-05 23.3 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EIE91571.1 - 0.036 13.8 0.0 0.079 12.6 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 EIE91571.1 - 0.1 12.1 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Rep_fac_C PF08542.6 EIE91572.1 - 5.9e-17 61.4 0.1 1.4e-16 60.2 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.24 EIE91572.1 - 3.4e-11 43.4 0.1 6.3e-11 42.6 0.1 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 EIE91572.1 - 4.3e-11 42.7 0.1 2.9e-09 36.7 0.1 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_14 PF13173.1 EIE91572.1 - 4.3e-07 29.8 0.0 9.5e-07 28.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 EIE91572.1 - 3.3e-06 26.0 0.1 0.011 14.4 0.0 2.1 1 1 1 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 EIE91572.1 - 1.4e-05 25.1 0.0 5.6e-05 23.1 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain Viral_helicase1 PF01443.13 EIE91572.1 - 8.5e-05 22.1 0.0 0.00015 21.3 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Mg_chelatase PF01078.16 EIE91572.1 - 0.00016 20.9 0.1 0.00077 18.6 0.0 2.0 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.1 EIE91572.1 - 0.00019 21.6 0.2 0.06 13.4 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.6 EIE91572.1 - 0.00032 20.2 0.0 0.00055 19.5 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EIE91572.1 - 0.00083 18.4 0.0 0.0029 16.6 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_10 PF12846.2 EIE91572.1 - 0.00087 18.8 0.3 0.087 12.2 0.2 3.2 1 1 0 1 1 1 1 AAA-like domain ArgK PF03308.11 EIE91572.1 - 0.003 16.4 0.1 0.0085 14.8 0.1 1.8 1 1 0 1 1 1 1 ArgK protein AAA_11 PF13086.1 EIE91572.1 - 0.0034 16.9 0.2 0.006 16.1 0.1 1.5 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 EIE91572.1 - 0.0051 16.5 0.2 0.053 13.2 0.0 2.2 2 0 0 2 2 2 1 NTPase DNA_pol3_delta PF06144.8 EIE91572.1 - 0.0059 16.1 0.0 0.01 15.3 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_19 PF13245.1 EIE91572.1 - 0.0065 16.2 0.0 0.015 15.0 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 EIE91572.1 - 0.035 14.4 0.0 0.082 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain DEAD PF00270.24 EIE91572.1 - 0.097 12.1 0.1 1.5 8.3 0.0 2.2 1 1 1 2 2 2 0 DEAD/DEAH box helicase DAP3 PF10236.4 EIE91572.1 - 0.11 11.4 0.1 3.9 6.3 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 tRNA-synt_1d PF00750.14 EIE91573.1 - 1.1e-90 303.9 6.2 1.9e-90 303.2 4.3 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 EIE91573.1 - 1.6e-22 79.7 0.1 6.7e-22 77.6 0.0 2.2 2 0 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 EIE91573.1 - 1.7e-08 34.8 0.0 4.5e-08 33.5 0.0 1.8 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain GST_C_2 PF13410.1 EIE91573.1 - 0.0018 18.1 0.0 0.0099 15.7 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain FANCI_S4 PF14678.1 EIE91574.1 - 6.1e-21 74.6 1.8 6.1e-21 74.6 1.3 1.9 2 1 0 2 2 2 1 FANCI solenoid 4 FANCI_HD2 PF14680.1 EIE91574.1 - 1.7e-11 43.7 0.1 1.7e-11 43.7 0.1 2.5 3 0 0 3 3 3 1 FANCI helical domain 2 FANCI_S3 PF14677.1 EIE91574.1 - 4.5e-11 42.5 1.3 1.1e-10 41.2 0.9 1.6 1 0 0 1 1 1 1 FANCI solenoid 3 DUF3895 PF13034.1 EIE91574.1 - 0.034 13.6 0.8 1.6 8.2 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3895) FANCI_S2 PF14676.1 EIE91575.1 - 5.9e-16 58.7 1.2 5.9e-16 58.7 0.9 3.2 3 1 1 4 4 4 1 FANCI solenoid 2 FANCI_S1 PF14675.1 EIE91575.1 - 1.6e-11 43.9 4.9 3.1e-10 39.8 0.2 3.8 1 1 2 3 3 3 1 FANCI solenoid 1 FANCI_HD1 PF14679.1 EIE91575.1 - 4.6e-05 23.0 1.1 0.011 15.4 0.2 3.8 2 1 1 3 3 3 1 FANCI helical domain 1 ECH_C PF13766.1 EIE91576.1 - 0.0011 19.1 0.0 0.0022 18.1 0.0 1.5 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region D5_N PF08706.6 EIE91577.1 - 0.0077 16.3 1.7 0.0077 16.3 1.2 1.7 2 0 0 2 2 2 1 D5 N terminal like Prefoldin_2 PF01920.15 EIE91577.1 - 0.025 14.3 16.7 0.16 11.7 5.3 2.8 1 1 1 2 2 2 0 Prefoldin subunit DUF1024 PF06260.7 EIE91577.1 - 0.1 12.7 3.2 0.1 12.7 0.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1024) Med4 PF10018.4 EIE91577.1 - 0.24 10.8 8.4 0.77 9.1 5.8 1.9 1 1 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Mer2 PF09074.5 EIE91577.1 - 0.31 10.9 16.4 0.4 10.5 10.4 2.0 1 1 0 1 1 1 0 Mer2 SopA_C PF13979.1 EIE91577.1 - 0.52 9.8 5.1 0.37 10.3 0.2 2.6 1 1 2 3 3 3 0 SopA-like catalytic domain FlxA PF14282.1 EIE91577.1 - 0.75 9.7 8.9 0.04 13.8 2.0 2.0 3 0 0 3 3 2 0 FlxA-like protein Syntaxin-6_N PF09177.6 EIE91577.1 - 1.1 9.6 10.2 0.31 11.4 3.0 2.7 2 1 1 3 3 3 0 Syntaxin 6, N-terminal DUF2203 PF09969.4 EIE91577.1 - 1.4 9.1 5.1 1.1 9.5 1.8 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) DivIVA PF05103.8 EIE91577.1 - 5.4 7.0 13.7 5.2 7.1 7.5 2.4 1 1 1 2 2 2 0 DivIVA protein Atg14 PF10186.4 EIE91577.1 - 6 5.7 16.7 4 6.3 4.3 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4140 PF13600.1 EIE91577.1 - 7.5 7.0 7.2 14 6.2 0.3 2.7 2 1 0 3 3 2 0 N-terminal domain of unknown function (DUF4140) APG6 PF04111.7 EIE91577.1 - 7.6 5.4 17.2 3.8 6.4 10.1 1.5 1 1 0 1 1 1 0 Autophagy protein Apg6 DUF342 PF03961.8 EIE91577.1 - 9.5 4.5 14.1 2.1 6.6 6.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF342) BicD PF09730.4 EIE91578.1 - 0.0027 16.1 15.7 0.0028 16.1 10.9 1.0 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D APG6 PF04111.7 EIE91578.1 - 0.004 16.2 19.7 0.0056 15.7 13.7 1.2 1 0 0 1 1 1 1 Autophagy protein Apg6 Cortex-I_coil PF09304.5 EIE91578.1 - 0.0075 16.2 10.7 0.0075 16.2 7.5 2.0 1 1 1 2 2 2 1 Cortexillin I, coiled coil V_ATPase_I PF01496.14 EIE91578.1 - 0.02 12.7 12.6 0.022 12.6 8.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family tRNA-synt_1g PF09334.6 EIE91578.1 - 0.053 12.1 2.2 0.052 12.1 1.6 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (M) PEPcase PF00311.12 EIE91578.1 - 0.88 7.3 11.7 1 7.1 8.1 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase Spc24 PF08286.6 EIE91578.1 - 1.9 8.1 17.0 0.036 13.7 3.4 2.6 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Macoilin PF09726.4 EIE91578.1 - 2 6.5 17.1 2.3 6.3 11.8 1.1 1 0 0 1 1 1 0 Transmembrane protein DivIC PF04977.10 EIE91578.1 - 3 7.3 22.7 2.3 7.7 3.6 3.3 2 1 1 3 3 3 0 Septum formation initiator TMPIT PF07851.8 EIE91578.1 - 4.7 6.1 18.2 3.5 6.5 3.6 2.0 1 1 1 2 2 2 0 TMPIT-like protein ASL_C PF08328.6 EIE91578.1 - 7.1 6.5 8.1 2.5 7.9 3.3 1.8 1 1 1 2 2 2 0 Adenylosuccinate lyase C-terminal VSG_B PF13206.1 EIE91578.1 - 8.1 5.4 7.9 9.3 5.2 5.5 1.0 1 0 0 1 1 1 0 Trypanosomal VSG domain Syntaxin-6_N PF09177.6 EIE91578.1 - 9.8 6.6 12.0 1.9e+02 2.5 8.3 2.3 1 1 0 1 1 1 0 Syntaxin 6, N-terminal WD40 PF00400.27 EIE91579.1 - 6e-31 105.1 8.5 1.3e-09 37.5 0.0 4.4 4 0 0 4 4 4 4 WD domain, G-beta repeat NLE PF08154.7 EIE91579.1 - 1.6e-23 82.4 0.1 3.4e-23 81.4 0.1 1.6 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.3 EIE91579.1 - 1.8e-06 26.4 2.8 0.0014 16.8 0.4 2.7 1 1 1 2 2 2 2 Nucleoporin Nup120/160 SGL PF08450.7 EIE91579.1 - 0.0068 15.8 0.1 1.5 8.1 0.1 2.2 1 1 1 2 2 2 2 SMP-30/Gluconolaconase/LRE-like region Nucleoporin_N PF08801.6 EIE91579.1 - 0.043 12.5 0.1 0.51 9.0 0.0 2.1 1 1 0 2 2 2 0 Nup133 N terminal like Mannosyl_trans3 PF11051.3 EIE91580.1 - 8.2e-44 149.9 0.0 2e-43 148.6 0.0 1.6 1 1 0 1 1 1 1 Mannosyltransferase putative Nucleotid_trans PF03407.11 EIE91580.1 - 0.05 13.3 0.1 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase Aminotran_4 PF01063.14 EIE91581.1 - 2.8e-22 79.3 0.0 3.3e-22 79.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV Glyco_trans_1_4 PF13692.1 EIE91581.1 - 0.049 13.7 0.0 3.2 7.9 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferases group 1 ThiF PF00899.16 EIE91582.1 - 3.8e-53 178.9 0.0 4e-32 110.8 0.0 2.6 2 0 0 2 2 2 2 ThiF family UBA_e1_C PF09358.5 EIE91582.1 - 3.4e-48 162.9 0.1 9e-48 161.5 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain UBACT PF02134.16 EIE91582.1 - 1.4e-39 133.4 0.2 4.5e-26 90.2 0.1 3.0 3 0 0 3 3 3 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EIE91582.1 - 9.8e-27 92.0 0.5 1.6e-22 78.6 0.1 2.4 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site RE_Alw26IDE PF09665.5 EIE91582.1 - 0.033 12.8 0.0 0.057 12.1 0.0 1.2 1 0 0 1 1 1 0 Type II restriction endonuclease (RE_Alw26IDE) MoeZ_MoeB PF05237.8 EIE91582.1 - 0.14 11.7 0.0 0.46 10.1 0.0 1.8 1 0 0 1 1 1 0 MoeZ/MoeB domain Pkinase PF00069.20 EIE91583.1 - 8.1e-62 208.7 0.2 1.3e-61 208.0 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE91583.1 - 1.4e-50 171.7 0.0 1.9e-50 171.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE91583.1 - 3.8e-07 29.3 0.2 0.0013 17.7 0.0 3.1 3 0 0 3 3 3 2 Kinase-like RIO1 PF01163.17 EIE91583.1 - 0.00028 20.2 0.1 0.00028 20.2 0.1 2.1 2 1 1 3 3 3 1 RIO1 family YrbL-PhoP_reg PF10707.4 EIE91583.1 - 0.001 18.4 0.1 0.0023 17.2 0.0 1.5 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL NARG2_C PF10505.4 EIE91583.1 - 0.0036 16.5 0.2 0.0066 15.6 0.1 1.4 1 0 0 1 1 1 1 NMDA receptor-regulated gene protein 2 C-terminus Kdo PF06293.9 EIE91583.1 - 0.052 12.6 0.0 0.089 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Glycoprotein_G PF00802.14 EIE91584.1 - 0.014 14.5 0.0 0.031 13.4 0.0 1.5 1 0 0 1 1 1 0 Pneumovirus attachment glycoprotein G gerPA PF10676.4 EIE91584.1 - 0.082 12.7 1.0 1.6 8.6 0.1 2.8 3 0 0 3 3 3 0 Spore germination protein gerPA/gerPF HABP4_PAI-RBP1 PF04774.10 EIE91585.1 - 0.00015 22.2 1.3 0.00015 22.2 0.9 3.6 2 1 0 3 3 3 1 Hyaluronan / mRNA binding family FAD_binding_7 PF03441.9 EIE91586.1 - 3.8e-46 157.5 1.2 7.4e-46 156.5 0.8 1.4 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 EIE91586.1 - 3.9e-11 42.9 2.6 1.7e-10 40.8 1.8 1.9 1 1 0 1 1 1 1 DNA photolyase 4HBT PF03061.17 EIE91587.1 - 2.9e-11 43.3 0.0 5e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily DUF676 PF05057.9 EIE91588.1 - 1.7e-23 83.1 0.2 6.7e-19 68.0 0.0 2.1 1 1 1 2 2 2 2 Putative serine esterase (DUF676) PGAP1 PF07819.8 EIE91588.1 - 0.00044 19.9 0.0 0.00057 19.5 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.20 EIE91588.1 - 0.0022 17.6 0.0 0.003 17.1 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EIE91588.1 - 0.051 13.3 0.0 0.65 9.7 0.0 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF915 PF06028.6 EIE91588.1 - 0.11 11.5 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_1 PF00561.15 EIE91588.1 - 0.12 11.9 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold adh_short_C2 PF13561.1 EIE91589.1 - 1.5e-25 90.4 0.3 1.7e-25 90.1 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EIE91589.1 - 1.2e-23 83.8 0.6 1.6e-23 83.4 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIE91589.1 - 3.6e-07 30.0 0.4 1.7e-06 27.8 0.3 1.9 1 1 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 EIE91589.1 - 0.0037 17.3 0.0 0.0073 16.4 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 EIE91589.1 - 0.074 12.0 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase Kelch_4 PF13418.1 EIE91590.1 - 1.1e-18 66.6 20.7 1.6e-05 24.5 0.0 6.8 6 1 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.1 EIE91590.1 - 2.2e-17 62.6 5.1 5.2e-06 26.2 0.3 5.4 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.1 EIE91590.1 - 2.5e-17 62.4 20.0 9.6e-05 22.4 0.0 6.5 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.1 EIE91590.1 - 2.5e-14 52.7 16.7 0.031 14.4 0.3 6.5 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.10 EIE91590.1 - 1.3e-08 34.2 4.1 0.0028 17.3 0.0 5.3 6 0 0 6 6 6 2 Kelch motif Kelch_1 PF01344.20 EIE91590.1 - 1.6e-06 27.5 12.7 0.00012 21.5 0.3 4.6 6 0 0 6 6 6 2 Kelch motif Nic96 PF04097.9 EIE91591.1 - 9e-88 294.9 8.0 1.2e-87 294.5 5.5 1.1 1 0 0 1 1 1 1 Nup93/Nic96 DUF3342 PF11822.3 EIE91591.1 - 0.0043 16.2 0.0 0.0079 15.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) DDE_3 PF13358.1 EIE91592.1 - 3.1e-15 56.1 0.0 3.4e-15 56.0 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease Cyclin_N PF00134.18 EIE91593.1 - 2.7e-11 43.1 0.2 3.7e-11 42.6 0.1 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 EIE91593.1 - 5.6e-10 39.8 0.2 9e-10 39.1 0.1 1.4 1 0 0 1 1 1 1 Cyclin Sugar_tr PF00083.19 EIE91595.1 - 3.2e-68 230.3 13.9 5.8e-65 219.6 6.8 3.6 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EIE91595.1 - 2.9e-16 59.1 14.8 1.2e-13 50.5 5.1 3.1 3 0 0 3 3 3 3 Major Facilitator Superfamily DUF4131 PF13567.1 EIE91595.1 - 8.3 5.7 8.8 11 5.3 0.7 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) O-antigen_lig PF13425.1 EIE91595.1 - 8.4 6.3 15.6 18 5.2 0.4 4.3 2 1 2 4 4 4 0 O-antigen ligase like membrane protein Myb_DNA-binding PF00249.26 EIE91596.1 - 1.1e-37 127.8 14.9 8.9e-13 48.0 0.1 5.4 6 0 0 6 6 6 4 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EIE91596.1 - 3.2e-35 120.0 13.4 8.8e-12 44.9 0.1 5.2 1 1 4 5 5 5 4 Myb-like DNA-binding domain Rap1_C PF11626.3 EIE91596.1 - 0.0028 17.5 4.0 5.9 6.8 0.1 3.4 2 1 0 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF3498 PF12004.3 EIE91596.1 - 0.04 13.0 0.0 0.06 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) Myb_DNA-bind_4 PF13837.1 EIE91596.1 - 1.8 8.7 16.8 9.7 6.4 0.0 5.8 4 4 1 5 5 5 0 Myb/SANT-like DNA-binding domain OTU PF02338.14 EIE91597.1 - 3.1e-07 31.0 0.0 7.1e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 OTU-like cysteine protease Plus-3 PF03126.13 EIE91598.1 - 1.6e-26 92.4 1.5 4e-26 91.1 0.0 2.4 3 0 0 3 3 3 1 Plus-3 domain YEATS PF03366.11 EIE91599.1 - 2.7e-16 59.0 0.0 5.1e-16 58.1 0.0 1.5 1 0 0 1 1 1 1 YEATS family Peptidase_S8 PF00082.17 EIE91600.1 - 5.8e-20 71.6 0.1 7.5e-20 71.2 0.0 1.1 1 0 0 1 1 1 1 Subtilase family PA PF02225.17 EIE91600.1 - 1.5e-13 50.2 0.1 1.3e-12 47.3 0.0 2.3 3 0 0 3 3 3 1 PA domain DUF1897 PF09005.5 EIE91600.1 - 0.064 12.7 0.3 0.12 11.8 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1897) Peptidase_S8 PF00082.17 EIE91601.1 - 5.1e-50 170.2 1.3 7.3e-50 169.6 0.9 1.2 1 0 0 1 1 1 1 Subtilase family PA PF02225.17 EIE91601.1 - 5.5e-18 64.5 0.0 1.6e-17 63.0 0.0 1.9 1 0 0 1 1 1 1 PA domain DUF1034 PF06280.7 EIE91601.1 - 0.016 15.5 0.1 0.042 14.2 0.1 1.7 1 0 0 1 1 1 0 Fn3-like domain (DUF1034) GARS_A PF01071.14 EIE91602.1 - 3e-83 278.1 0.0 5.5e-83 277.3 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 EIE91602.1 - 2.1e-39 134.0 1.8 2.1e-37 127.5 0.0 3.0 3 0 0 3 3 3 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.11 EIE91602.1 - 5.1e-30 103.5 0.6 1.6e-29 101.9 0.4 1.9 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS_C PF02769.17 EIE91602.1 - 1.3e-28 99.9 0.0 4.2e-28 98.2 0.0 1.9 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.19 EIE91602.1 - 6.1e-16 58.4 2.3 3.1e-15 56.1 0.7 2.8 3 0 0 3 3 3 1 AIR synthase related protein, N-terminal domain ATP-grasp_4 PF13535.1 EIE91602.1 - 5.5e-10 39.2 0.0 1.4e-09 37.9 0.0 1.6 1 1 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EIE91602.1 - 7.5e-09 34.7 0.0 1.5e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EIE91602.1 - 4.8e-06 26.0 0.0 9.8e-06 25.0 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 EIE91602.1 - 0.00026 20.3 0.2 0.0006 19.1 0.1 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain RimK PF08443.6 EIE91602.1 - 0.00073 19.0 0.0 0.0021 17.5 0.0 1.7 2 0 0 2 2 2 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 EIE91602.1 - 0.0037 17.1 0.0 0.015 15.1 0.0 2.0 2 1 0 2 2 2 1 ATP-grasp domain ATP-grasp_2 PF08442.5 EIE91602.1 - 0.036 13.4 0.1 0.069 12.5 0.1 1.3 1 0 0 1 1 1 0 ATP-grasp domain QH-AmDH_gamma PF08992.6 EIE91603.1 - 0.017 14.8 0.0 0.054 13.2 0.0 1.8 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase, gamma subunit HEAT PF02985.17 EIE91604.1 - 8.5e-23 78.3 12.7 0.00014 21.6 0.0 9.6 10 1 0 10 10 10 5 HEAT repeat HEAT_2 PF13646.1 EIE91604.1 - 1.6e-17 63.5 1.1 6.3e-06 26.3 0.0 7.6 2 2 7 10 10 10 6 HEAT repeats HEAT_EZ PF13513.1 EIE91604.1 - 1e-14 54.4 12.1 7.8e-09 35.7 0.0 7.9 8 1 0 8 8 8 2 HEAT-like repeat IBN_N PF03810.14 EIE91604.1 - 1.2e-13 50.8 0.1 6.8e-12 45.1 0.0 3.0 2 0 0 2 2 2 1 Importin-beta N-terminal domain Arm PF00514.18 EIE91604.1 - 8.5e-06 25.4 1.1 0.011 15.5 0.0 4.7 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat MMS19_C PF12460.3 EIE91604.1 - 0.00056 18.7 6.9 0.3 9.7 0.2 3.9 4 0 0 4 4 4 2 RNAPII transcription regulator C-terminal CLASP_N PF12348.3 EIE91604.1 - 0.0021 17.4 3.5 6 6.1 0.2 4.5 3 1 0 3 3 3 2 CLASP N terminal Xpo1 PF08389.7 EIE91604.1 - 0.0087 15.9 12.4 0.093 12.6 0.0 4.6 6 1 0 6 6 6 2 Exportin 1-like protein TIP120 PF08623.5 EIE91604.1 - 0.018 14.5 0.8 11 5.5 0.1 3.7 4 0 0 4 4 4 0 TATA-binding protein interacting (TIP20) MMS19_N PF14500.1 EIE91604.1 - 0.17 11.1 2.7 0.26 10.5 0.1 2.5 2 1 0 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II Cnd3 PF12719.2 EIE91604.1 - 0.19 10.6 4.8 0.44 9.4 0.2 3.4 3 1 1 4 4 4 0 Nuclear condensing complex subunits, C-term domain Bromodomain PF00439.20 EIE91605.1 - 1.2e-23 82.8 0.2 2.4e-23 81.8 0.2 1.5 1 0 0 1 1 1 1 Bromodomain GvpL_GvpF PF06386.6 EIE91605.1 - 0.025 14.1 1.3 0.034 13.7 0.9 1.1 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Homeobox PF00046.24 EIE91606.1 - 1.3e-16 59.9 2.4 2.5e-16 59.0 1.6 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EIE91606.1 - 0.0036 16.9 0.3 0.014 15.0 0.0 2.1 2 0 0 2 2 2 1 Homeobox KN domain HTH_23 PF13384.1 EIE91606.1 - 0.0077 15.8 0.9 0.016 14.8 0.0 2.1 2 1 1 3 3 3 1 Homeodomain-like domain GerE PF00196.14 EIE91606.1 - 0.096 12.0 0.0 0.27 10.5 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family WD40 PF00400.27 EIE91607.1 - 4.7e-14 51.6 2.6 6.4e-07 29.0 0.0 3.6 3 0 0 3 3 3 3 WD domain, G-beta repeat PIF1 PF05970.9 EIE91608.1 - 2.8e-109 365.4 0.0 4e-109 364.9 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.1 EIE91608.1 - 1.7e-64 216.9 0.1 3.8e-64 215.8 0.0 1.7 2 0 0 2 2 1 1 Helitron helicase-like domain at N-terminus ResIII PF04851.10 EIE91608.1 - 1.9e-05 24.6 0.0 5.6e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 EIE91608.1 - 0.00021 20.9 0.0 0.00069 19.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EIE91608.1 - 0.0019 17.9 0.0 0.005 16.5 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain T2SE PF00437.15 EIE91608.1 - 0.0023 16.8 0.0 0.004 16.1 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein Herpes_Helicase PF02689.9 EIE91608.1 - 0.0024 15.7 0.0 0.0038 15.0 0.0 1.2 1 0 0 1 1 1 1 Helicase AAA_5 PF07728.9 EIE91608.1 - 0.005 16.5 0.0 0.014 15.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TrwB_AAD_bind PF10412.4 EIE91608.1 - 0.013 14.1 0.0 0.021 13.4 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_10 PF12846.2 EIE91608.1 - 0.013 14.9 0.1 0.32 10.4 0.0 2.6 2 0 0 2 2 2 0 AAA-like domain DAP3 PF10236.4 EIE91608.1 - 0.076 11.9 0.0 0.15 10.9 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.1 EIE91608.1 - 0.08 12.9 0.0 0.47 10.4 0.0 2.3 3 0 0 3 3 3 0 AAA ATPase domain UvrD_C_2 PF13538.1 EIE91608.1 - 0.1 12.7 0.0 0.26 11.4 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Sigma54_activat PF00158.21 EIE91608.1 - 0.11 11.9 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.11 EIE91608.1 - 0.2 10.8 0.0 0.4 9.8 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein UQ_con PF00179.21 EIE91609.1 - 1.7e-29 102.0 0.3 3.5e-29 101.0 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Pro_isomerase PF00160.16 EIE91610.1 - 2.4e-48 164.2 0.2 2.9e-48 163.9 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Sdh5 PF03937.11 EIE91612.1 - 3.6e-25 87.4 0.5 5.1e-25 86.9 0.3 1.2 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase SpoVR PF04293.8 EIE91612.1 - 0.088 11.1 0.7 0.11 10.8 0.5 1.1 1 0 0 1 1 1 0 SpoVR like protein Arf PF00025.16 EIE91613.1 - 6.7e-67 224.0 0.1 8.2e-67 223.8 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EIE91613.1 - 1e-13 50.9 0.0 1.2e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 EIE91613.1 - 2.9e-12 46.1 0.0 3.7e-12 45.8 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EIE91613.1 - 2.9e-11 42.6 2.6 2.3e-07 29.8 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EIE91613.1 - 3.2e-11 42.8 0.0 3.8e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EIE91613.1 - 9.7e-08 32.5 0.0 1.3e-07 32.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EIE91613.1 - 5.9e-05 23.0 0.0 7.5e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 EIE91613.1 - 0.0017 17.4 0.2 0.0018 17.3 0.1 1.3 1 1 0 1 1 1 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 EIE91613.1 - 0.0093 15.4 0.1 0.06 12.7 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain L27 PF02828.11 EIE91613.1 - 0.061 13.0 0.5 0.16 11.6 0.1 1.8 2 0 0 2 2 2 0 L27 domain DUF3986 PF13143.1 EIE91613.1 - 0.2 12.1 0.6 0.5 10.8 0.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3986) P5CR_dimer PF14748.1 EIE91614.1 - 1.6e-38 131.0 2.0 2.9e-38 130.1 1.4 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 EIE91614.1 - 3.5e-18 65.8 0.7 3.1e-17 62.7 0.0 2.4 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 EIE91614.1 - 5.1e-08 32.7 2.1 3.7e-07 30.0 0.8 2.6 2 1 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus OCD_Mu_crystall PF02423.10 EIE91614.1 - 0.00047 19.0 0.0 0.0017 17.2 0.0 1.9 2 0 0 2 2 2 1 Ornithine cyclodeaminase/mu-crystallin family CoA_binding_2 PF13380.1 EIE91614.1 - 0.0077 16.3 0.5 0.03 14.4 0.1 2.0 2 1 0 2 2 2 1 CoA binding domain Semialdhyde_dh PF01118.19 EIE91614.1 - 0.01 16.1 0.4 0.29 11.4 0.0 2.4 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain PDH PF02153.12 EIE91614.1 - 0.038 12.8 0.1 0.06 12.2 0.1 1.3 1 0 0 1 1 1 0 Prephenate dehydrogenase Rossmann-like PF10727.4 EIE91614.1 - 0.076 12.7 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Rossmann-like domain Zn_clus PF00172.13 EIE91615.1 - 0.0018 18.1 16.0 0.0032 17.3 11.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NPBW PF15180.1 EIE91615.1 - 0.098 12.2 0.1 0.098 12.2 0.1 2.4 3 0 0 3 3 3 0 Neuropeptides B and W HypA PF01155.14 EIE91615.1 - 3 7.5 6.1 5.2 6.8 4.2 1.3 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Ribosomal_60s PF00428.14 EIE91615.1 - 9.3 6.7 8.1 4.4 7.7 2.6 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein RRM_1 PF00076.17 EIE91617.1 - 5e-18 64.4 0.1 7.9e-17 60.6 0.0 2.7 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE91617.1 - 1e-11 44.6 0.0 2.1e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE91617.1 - 2.7e-05 23.9 0.0 7.7e-05 22.4 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 EIE91617.1 - 0.00049 19.7 0.1 0.021 14.4 0.0 2.6 2 1 0 2 2 2 1 Poly-adenylate binding protein, unique domain LysM PF01476.15 EIE91618.1 - 8.5e-09 35.1 0.1 1.2e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 LysM domain CytadhesinP1 PF12378.3 EIE91619.1 - 0.18 11.7 1.3 0.52 10.2 0.2 2.1 2 0 0 2 2 2 0 Trypsin-sensitive surface-exposed protein ABC2_membrane PF01061.19 EIE91620.1 - 0.0014 17.8 6.8 0.0014 17.8 4.7 2.2 1 1 1 2 2 2 1 ABC-2 type transporter DUF420 PF04238.7 EIE91620.1 - 0.01 15.7 14.4 0.026 14.4 3.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF420) Transmemb_17 PF09799.4 EIE91620.1 - 0.49 10.7 16.4 0.091 13.1 8.0 2.1 2 1 0 2 2 2 0 Predicted membrane protein DUF1751 PF08551.5 EIE91620.1 - 2.7 8.3 10.2 0.19 12.0 1.1 2.4 1 1 0 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) Chromo PF00385.19 EIE91621.1 - 1.9e-11 43.4 1.5 1.9e-11 43.4 1.0 3.0 4 0 0 4 4 4 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.14 EIE91621.1 - 2.9e-06 27.0 0.1 0.00013 21.6 0.0 2.4 2 0 0 2 2 2 1 Chromo shadow domain Macoilin PF09726.4 EIE91621.1 - 0.96 7.6 11.2 1.1 7.5 7.7 1.1 1 0 0 1 1 1 0 Transmembrane protein Proteasome PF00227.21 EIE91623.1 - 2.9e-62 209.3 0.2 3.6e-62 209.0 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EIE91623.1 - 1e-14 53.5 0.2 1.7e-14 52.7 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DSPc PF00782.15 EIE91624.1 - 1.6e-33 115.0 0.8 2e-33 114.7 0.2 1.4 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EIE91624.1 - 4e-05 23.0 0.0 5.7e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EIE91624.1 - 0.0004 20.4 0.0 0.00048 20.1 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate Init_tRNA_PT PF04179.7 EIE91624.1 - 0.022 13.6 0.1 0.022 13.6 0.0 1.1 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase RhoGAP PF00620.22 EIE91625.1 - 1.1e-19 70.5 0.1 1.7e-15 56.9 0.0 2.9 2 1 1 3 3 3 2 RhoGAP domain MyTH4 PF00784.12 EIE91625.1 - 6.9e-09 35.6 0.5 5.4e-08 32.7 0.1 2.7 3 1 1 4 4 4 1 MyTH4 domain Peripla_BP_2 PF01497.13 EIE91625.1 - 0.064 12.3 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding protein CNH PF00780.17 EIE91626.1 - 1.2e-54 185.6 0.0 1.8e-54 185.0 0.0 1.2 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.15 EIE91626.1 - 1.3e-24 87.0 0.1 3.3e-24 85.7 0.1 1.7 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.1 EIE91626.1 - 2e-20 73.0 0.1 9.3e-20 70.9 0.0 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 EIE91626.1 - 0.00084 19.5 0.0 0.0027 17.8 0.0 2.0 1 0 0 1 1 1 1 PH domain CBP4 PF07960.6 EIE91626.1 - 0.78 9.3 6.9 3.7 7.1 0.0 2.3 2 0 0 2 2 2 0 CBP4 PAS_9 PF13426.1 EIE91627.1 - 1.6e-25 89.5 0.0 4.6e-18 65.5 0.0 3.8 3 1 0 3 3 3 3 PAS domain PAS_3 PF08447.6 EIE91627.1 - 8.1e-21 73.9 0.0 1.9e-11 43.9 0.0 4.2 3 1 0 3 3 3 3 PAS fold PAS_4 PF08448.5 EIE91627.1 - 4.1e-17 62.1 0.0 1.1e-06 28.6 0.0 3.7 4 0 0 4 4 4 3 PAS fold GATA PF00320.22 EIE91627.1 - 3.8e-15 54.9 2.9 9.8e-15 53.6 2.0 1.7 1 0 0 1 1 1 1 GATA zinc finger PAS PF00989.19 EIE91627.1 - 2.7e-11 43.2 0.0 0.013 15.2 0.0 4.0 3 1 0 3 3 3 3 PAS fold PAS_11 PF14598.1 EIE91627.1 - 6.6e-11 42.1 0.0 7.3e-06 25.9 0.0 3.9 4 1 0 4 4 4 2 PAS domain Pkinase PF00069.20 EIE91628.1 - 2.7e-72 243.0 0.0 3.3e-72 242.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE91628.1 - 6.3e-30 104.0 0.0 9.2e-30 103.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE91628.1 - 0.00035 19.6 0.0 0.0015 17.5 0.0 1.9 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.9 EIE91628.1 - 0.012 14.7 0.7 0.016 14.2 0.1 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIE91628.1 - 0.058 13.1 0.1 0.094 12.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family GTP_EFTU PF00009.22 EIE91629.1 - 6.5e-61 205.0 0.4 9.5e-61 204.5 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EIE91629.1 - 2.7e-32 110.8 0.4 1.2e-31 108.7 0.1 2.1 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EIE91629.1 - 2.4e-16 59.5 2.6 2.4e-16 59.5 1.8 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EIE91629.1 - 3.1e-05 23.9 0.0 5.4e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EIE91629.1 - 0.0049 17.3 0.0 0.0084 16.5 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Alba PF01918.16 EIE91629.1 - 0.035 13.7 0.1 0.11 12.1 0.0 1.9 2 0 0 2 2 2 0 Alba cobW PF02492.14 EIE91629.1 - 0.041 13.3 0.6 0.078 12.4 0.0 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 EIE91629.1 - 0.049 13.1 0.3 5.2 6.5 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MaoC_dehydrat_N PF13452.1 EIE91630.1 - 2.6e-05 24.0 0.0 5.6e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase DUF648 PF04890.8 EIE91630.1 - 0.011 14.8 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF648) Sugar_tr PF00083.19 EIE91631.1 - 1.2e-76 258.1 30.1 1.5e-76 257.8 20.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIE91631.1 - 1.9e-19 69.6 32.8 4.6e-19 68.3 19.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DDE_3 PF13358.1 EIE91633.1 - 3.5e-09 36.5 0.0 6.7e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_21 PF13276.1 EIE91633.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 HTH-like domain HTH_32 PF13565.1 EIE91633.1 - 0.12 13.2 0.0 0.35 11.6 0.0 1.8 3 0 0 3 3 3 0 Homeodomain-like domain Birna_RdRp PF04197.7 EIE91636.1 - 0.071 11.1 0.2 0.069 11.1 0.2 1.0 1 0 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) Symplekin_C PF12295.3 EIE91642.1 - 0.038 13.9 0.1 0.072 13.0 0.0 1.4 1 0 0 1 1 1 0 Symplekin tight junction protein C terminal TFIID-18kDa PF02269.11 EIE91642.1 - 0.062 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit DUF1765 PF08578.5 EIE91643.1 - 0.036 14.1 0.1 0.57 10.2 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1765) Acetyltransf_1 PF00583.19 EIE91644.1 - 1.1e-14 54.2 0.1 5.5e-14 51.9 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EIE91644.1 - 1.4e-10 41.1 0.1 2.5e-10 40.3 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EIE91644.1 - 0.0028 17.4 0.0 0.0038 17.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EIE91644.1 - 0.056 13.5 0.0 0.11 12.6 0.0 1.6 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 EIE91644.1 - 0.07 12.8 0.1 0.25 11.1 0.0 1.8 2 0 0 2 2 2 0 FR47-like protein Y_phosphatase2 PF03162.8 EIE91644.1 - 0.076 12.3 0.4 0.093 12.0 0.3 1.4 1 1 0 1 1 1 0 Tyrosine phosphatase family TPR_MLP1_2 PF07926.7 EIE91647.1 - 0.00011 21.9 0.4 0.00015 21.5 0.3 1.2 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein Paramyx_P_V_C PF03210.8 EIE91647.1 - 0.0054 16.6 0.8 0.0091 15.8 0.4 1.5 1 1 0 1 1 1 1 Paramyxovirus P/V phosphoprotein C-terminal DUF972 PF06156.8 EIE91647.1 - 0.013 15.8 0.8 0.033 14.5 0.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Phage_GP20 PF06810.6 EIE91647.1 - 0.057 12.8 0.1 0.08 12.3 0.1 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 GAS PF13851.1 EIE91647.1 - 0.089 11.9 0.1 0.13 11.4 0.1 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DivIC PF04977.10 EIE91647.1 - 0.091 12.2 0.3 0.17 11.4 0.2 1.4 1 0 0 1 1 1 0 Septum formation initiator Reo_sigmaC PF04582.7 EIE91647.1 - 0.094 11.8 4.3 0.13 11.4 3.0 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Tropomyosin_1 PF12718.2 EIE91647.1 - 0.11 12.3 0.1 0.16 11.7 0.1 1.1 1 0 0 1 1 1 0 Tropomyosin like DUF4200 PF13863.1 EIE91647.1 - 0.12 12.3 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) bZIP_2 PF07716.10 EIE91647.1 - 0.13 12.1 2.6 1.2 9.0 0.1 2.4 1 1 1 2 2 2 0 Basic region leucine zipper DivIVA PF05103.8 EIE91647.1 - 0.15 12.1 0.3 0.31 11.1 0.1 1.6 1 1 0 1 1 1 0 DivIVA protein TMF_DNA_bd PF12329.3 EIE91647.1 - 0.35 10.7 2.1 0.68 9.7 1.4 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding RHIM PF12721.2 EIE91647.1 - 1.2 9.5 7.1 0.24 11.8 1.6 2.3 2 0 0 2 2 2 0 RIP homotypic interaction motif DDE_3 PF13358.1 EIE91648.1 - 4.6e-20 71.8 0.1 8.8e-20 70.9 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE91648.1 - 7.9e-19 67.4 2.1 2e-18 66.2 0.8 2.2 3 0 0 3 3 3 1 Transposase HTH_29 PF13551.1 EIE91648.1 - 3.5e-07 30.3 0.7 1.3e-06 28.4 0.5 2.0 1 0 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.1 EIE91648.1 - 0.0025 18.5 0.3 0.0025 18.5 0.2 4.0 5 1 1 6 6 6 1 Homeodomain-like domain Ku_PK_bind PF08785.6 EIE91648.1 - 0.0027 17.6 0.1 0.0068 16.2 0.0 1.8 2 0 0 2 2 2 1 Ku C terminal domain like HTH_23 PF13384.1 EIE91648.1 - 0.0034 16.9 0.7 0.058 13.0 0.0 3.0 3 0 0 3 3 3 1 Homeodomain-like domain rve PF00665.21 EIE91648.1 - 0.009 16.1 0.0 0.03 14.4 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain HTH_12 PF08461.5 EIE91648.1 - 0.22 11.2 0.2 0.22 11.2 0.1 2.4 3 0 0 3 3 3 0 Ribonuclease R winged-helix domain HTH_17 PF12728.2 EIE91648.1 - 0.37 11.0 2.2 1.6 9.0 0.2 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain Leader_Erm PF08253.6 EIE91649.1 - 0.33 10.4 0.3 0.33 10.4 0.2 2.1 2 0 0 2 2 2 0 Erm Leader peptide rve PF00665.21 EIE91650.1 - 1.8e-24 86.1 0.0 5.6e-24 84.5 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE91650.1 - 2.3e-16 59.7 0.0 4.9e-16 58.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE91650.1 - 7.7e-11 41.5 0.6 2.6e-10 39.8 0.4 2.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 EIE91650.1 - 0.0006 19.1 1.0 0.001 18.4 0.1 2.0 2 0 0 2 2 2 1 His(2)-Cys(2) zinc finger UBN2_2 PF14227.1 EIE91650.1 - 0.0058 16.1 1.8 0.076 12.5 0.0 2.8 3 0 0 3 3 3 1 gag-polypeptide of LTR copia-type rve_3 PF13683.1 EIE91650.1 - 0.012 15.0 0.0 0.041 13.3 0.0 1.9 1 0 0 1 1 1 0 Integrase core domain RVT_1 PF00078.22 EIE91651.1 - 5.6e-23 81.4 0.5 1.2e-22 80.3 0.3 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EIE91651.1 - 2.6e-20 72.7 0.0 5.9e-20 71.5 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVP PF00077.15 EIE91651.1 - 5.7e-07 29.3 0.0 1.6e-06 27.9 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EIE91651.1 - 3.4e-06 26.7 0.0 7.5e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EIE91651.1 - 6.7e-06 26.5 0.0 1.4e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.6 EIE91651.1 - 0.0024 17.8 0.0 0.0062 16.4 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease rve_3 PF13683.1 EIE91651.1 - 0.0028 17.1 0.0 0.0078 15.7 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.5 EIE91651.1 - 0.035 13.4 0.7 0.073 12.4 0.5 1.6 1 0 0 1 1 1 0 His(2)-Cys(2) zinc finger Asp_protease PF09668.5 EIE91651.1 - 0.04 13.4 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease Transgly PF00912.17 EIE91651.1 - 0.05 12.9 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Transglycosylase HTH_Tnp_Tc3_2 PF01498.13 EIE91652.1 - 6.1e-18 64.6 0.6 6.1e-18 64.6 0.4 2.4 2 1 1 3 3 3 1 Transposase HTH_29 PF13551.1 EIE91652.1 - 1.4e-09 38.0 1.8 2.9e-09 37.0 1.2 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EIE91652.1 - 1.6e-06 27.5 0.3 4.1e-05 23.0 0.1 3.0 3 0 0 3 3 3 1 Homeodomain-like domain HTH_32 PF13565.1 EIE91652.1 - 5.5e-05 23.8 3.5 0.00019 22.1 0.2 3.0 3 1 1 4 4 4 1 Homeodomain-like domain HTH_28 PF13518.1 EIE91652.1 - 0.0008 19.3 0.4 0.0027 17.6 0.1 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_7 PF02796.10 EIE91652.1 - 0.031 14.1 1.1 0.27 11.1 0.1 2.6 2 1 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_3 PF01381.17 EIE91652.1 - 0.14 11.9 0.6 0.25 11.2 0.1 1.6 2 0 0 2 2 2 0 Helix-turn-helix HTH_38 PF13936.1 EIE91652.1 - 0.16 11.5 0.5 6 6.5 0.0 2.9 2 1 0 2 2 2 0 Helix-turn-helix domain NUMOD3 PF07460.6 EIE91652.1 - 0.39 10.6 0.1 0.39 10.6 0.1 1.9 2 0 0 2 2 2 0 NUMOD3 motif (2 copies) TPR_MLP1_2 PF07926.7 EIE91654.1 - 9.7e-05 22.1 0.3 0.00014 21.6 0.2 1.2 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein HALZ PF02183.13 EIE91654.1 - 0.00064 19.3 1.0 0.0015 18.1 0.4 1.9 1 1 0 1 1 1 1 Homeobox associated leucine zipper DUF904 PF06005.7 EIE91654.1 - 0.0072 16.5 2.4 0.015 15.5 1.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF904) Reo_sigmaC PF04582.7 EIE91654.1 - 0.014 14.5 3.8 0.021 14.0 2.7 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF972 PF06156.8 EIE91654.1 - 0.023 15.0 0.4 0.044 14.1 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) ADIP PF11559.3 EIE91654.1 - 0.029 14.2 2.7 0.059 13.2 1.8 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding MAD PF05557.8 EIE91654.1 - 0.029 12.4 0.7 0.04 12.0 0.5 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein Mod_r PF07200.8 EIE91654.1 - 0.033 14.0 0.8 0.068 13.0 0.5 1.5 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Cluap1 PF10234.4 EIE91654.1 - 0.039 13.1 0.6 0.058 12.5 0.4 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 DivIC PF04977.10 EIE91654.1 - 0.047 13.1 1.3 0.093 12.2 0.5 1.7 1 1 1 2 2 2 0 Septum formation initiator Phage_GP20 PF06810.6 EIE91654.1 - 0.06 12.7 0.7 0.1 12.0 0.5 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 GAS PF13851.1 EIE91654.1 - 0.069 12.3 1.9 0.1 11.7 1.3 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Baculo_PEP_C PF04513.7 EIE91654.1 - 0.073 12.8 7.2 0.13 12.1 5.0 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF342 PF03961.8 EIE91654.1 - 0.12 10.7 0.2 0.16 10.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF2205 PF10224.4 EIE91654.1 - 0.14 11.7 2.3 0.24 10.9 1.6 1.3 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) bZIP_2 PF07716.10 EIE91654.1 - 0.22 11.3 3.3 3.7 7.4 0.1 2.5 1 1 1 2 2 2 0 Basic region leucine zipper DivIVA PF05103.8 EIE91654.1 - 0.27 11.2 1.9 0.41 10.7 0.1 2.0 1 1 1 2 2 2 0 DivIVA protein Rootletin PF15035.1 EIE91654.1 - 0.68 9.8 4.5 1.2 9.0 3.1 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion RVT_1 PF00078.22 EIE91655.1 - 7.9e-26 90.7 0.0 1.3e-25 90.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EIE91655.1 - 2e-05 24.1 0.0 7.2e-05 22.3 0.0 2.1 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Leader_Erm PF08253.6 EIE91656.1 - 0.33 10.4 0.3 0.33 10.4 0.2 2.1 2 0 0 2 2 2 0 Erm Leader peptide Transposase_21 PF02992.9 EIE91657.1 - 1e-21 77.1 0.0 2.1e-21 76.0 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 DUF1258 PF06869.7 EIE91657.1 - 0.0046 16.0 0.0 0.0098 15.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) LysR_substrate PF03466.15 EIE91657.1 - 0.17 10.9 0.0 0.29 10.1 0.0 1.3 1 0 0 1 1 1 0 LysR substrate binding domain FKBP_N PF01346.13 EIE91658.1 - 0.0013 18.7 1.0 0.003 17.5 0.7 1.5 1 0 0 1 1 1 1 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase LAG1-DNAbind PF09271.6 EIE91658.1 - 0.026 14.9 0.3 0.052 14.0 0.2 1.5 1 0 0 1 1 1 0 LAG1, DNA binding HTH_37 PF13744.1 EIE91658.1 - 1.2 8.9 7.2 18 5.2 3.7 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain RRF_GI PF12614.3 EIE91659.1 - 0.022 14.5 0.1 0.023 14.5 0.1 1.2 1 0 0 1 1 1 0 Ribosome recycling factor DDE_3 PF13358.1 EIE91661.1 - 5.9e-18 65.0 0.1 1.4e-17 63.8 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE91661.1 - 5.3e-12 45.6 1.0 5.3e-12 45.6 0.7 2.2 3 0 0 3 3 3 1 Transposase HTH_29 PF13551.1 EIE91661.1 - 0.00019 21.5 0.7 0.00039 20.5 0.1 1.8 2 0 0 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.1 EIE91661.1 - 0.00092 18.7 0.1 0.0025 17.4 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_7 PF02796.10 EIE91661.1 - 0.0072 16.1 0.0 0.021 14.7 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_30 PF13556.1 EIE91661.1 - 0.021 14.4 0.0 0.17 11.4 0.0 2.1 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain HTH_38 PF13936.1 EIE91661.1 - 0.03 13.8 0.0 0.11 12.0 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain RecX PF02631.11 EIE91661.1 - 0.12 12.5 0.3 0.26 11.4 0.2 1.5 1 0 0 1 1 1 0 RecX family HTH_Tnp_Tc3_2 PF01498.13 EIE91662.1 - 2.5e-06 27.4 0.1 3e-06 27.1 0.1 1.2 1 0 0 1 1 1 1 Transposase Leader_Erm PF08253.6 EIE91663.1 - 0.33 10.4 0.3 0.33 10.4 0.2 2.1 2 0 0 2 2 2 0 Erm Leader peptide Retrotrans_gag PF03732.12 EIE91665.1 - 0.0032 17.4 1.0 0.0032 17.4 0.7 1.9 2 0 0 2 2 2 1 Retrotransposon gag protein UBN2_2 PF14227.1 EIE91665.1 - 0.011 15.2 0.0 0.023 14.2 0.0 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type DUF2666 PF10869.3 EIE91665.1 - 0.13 12.2 0.1 0.26 11.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2666) DDE_3 PF13358.1 EIE91666.1 - 1.2e-09 38.0 2.7 2.2e-09 37.2 0.7 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_3 PF13358.1 EIE91667.1 - 3.8e-16 59.1 0.0 5e-16 58.7 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 EIE91668.1 - 4.7e-07 29.9 0.0 9.9e-07 28.9 0.0 1.6 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.1 EIE91668.1 - 6.9e-07 29.9 0.1 2.1e-06 28.4 0.0 1.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_1 PF01527.15 EIE91668.1 - 4.5e-05 23.3 0.0 0.00012 21.9 0.0 1.7 2 0 0 2 2 2 1 Transposase HTH_28 PF13518.1 EIE91668.1 - 9e-05 22.3 0.0 0.0012 18.7 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.1 EIE91668.1 - 0.00043 19.8 0.0 0.0069 16.0 0.0 2.4 2 0 0 2 2 2 1 Homeodomain-like domain TylF PF05711.6 EIE91668.1 - 0.0056 15.7 0.0 0.0086 15.1 0.0 1.2 1 0 0 1 1 1 1 Macrocin-O-methyltransferase (TylF) BDV_P24 PF06595.6 EIE91668.1 - 0.022 14.5 0.3 0.047 13.4 0.0 1.6 1 1 1 2 2 2 0 Borna disease virus P24 protein Terminase_5 PF06056.7 EIE91668.1 - 0.065 12.8 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) HTH_30 PF13556.1 EIE91668.1 - 0.11 12.1 0.0 0.25 10.9 0.0 1.6 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain FadA PF09403.5 EIE91668.1 - 0.12 12.3 1.5 0.15 12.0 0.3 1.6 2 0 0 2 2 2 0 Adhesion protein FadA Raftlin PF15250.1 EIE91670.1 - 0.0041 15.7 3.9 0.0066 15.0 2.7 1.2 1 0 0 1 1 1 1 Raftlin CUE PF02845.11 EIE91670.1 - 0.029 13.8 0.4 0.69 9.4 0.1 2.4 2 0 0 2 2 2 0 CUE domain UBA PF00627.26 EIE91670.1 - 0.054 13.3 0.0 0.097 12.5 0.0 1.5 1 0 0 1 1 1 0 UBA/TS-N domain DUF4557 PF15101.1 EIE91670.1 - 2.5 7.9 11.4 6.1 6.6 7.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DDE_3 PF13358.1 EIE91671.1 - 2.4e-31 108.4 0.0 5.5e-31 107.2 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 EIE91671.1 - 1.8e-07 31.3 0.0 5.3e-07 29.7 0.0 1.8 1 0 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.1 EIE91671.1 - 1e-06 29.4 0.3 5.7e-06 27.0 0.0 2.4 3 0 0 3 3 3 1 Homeodomain-like domain HTH_Tnp_1 PF01527.15 EIE91671.1 - 4.1e-06 26.6 0.5 0.00032 20.5 0.0 2.6 2 1 0 2 2 2 1 Transposase rve PF00665.21 EIE91671.1 - 7e-05 22.9 0.0 0.00022 21.3 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain HTH_28 PF13518.1 EIE91671.1 - 0.00012 21.9 0.2 0.0029 17.5 0.0 2.8 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_23 PF13384.1 EIE91671.1 - 0.0005 19.6 0.1 0.016 14.8 0.0 2.7 3 0 0 3 3 3 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.13 EIE91671.1 - 0.019 15.0 0.1 0.063 13.3 0.1 2.0 1 0 0 1 1 1 0 Transposase BDV_P24 PF06595.6 EIE91671.1 - 0.054 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Borna disease virus P24 protein Terminase_5 PF06056.7 EIE91671.1 - 0.072 12.6 0.0 0.3 10.6 0.0 2.0 2 0 0 2 2 2 0 Putative ATPase subunit of terminase (gpP-like) HTH_Tnp_Tc3_2 PF01498.13 EIE91672.1 - 1.2e-11 44.4 1.5 2.1e-11 43.7 0.2 2.0 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 EIE91672.1 - 0.0039 17.3 0.4 0.01 15.9 0.0 1.8 2 0 0 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.1 EIE91672.1 - 0.0068 16.0 0.1 0.018 14.7 0.1 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_30 PF13556.1 EIE91672.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain UMP1 PF05348.6 EIE91673.1 - 4.3e-36 123.7 0.4 5e-36 123.5 0.2 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 GATA PF00320.22 EIE91674.1 - 0.00046 19.4 4.6 0.00046 19.4 3.2 1.7 2 0 0 2 2 2 1 GATA zinc finger Lectin_N PF03954.9 EIE91674.1 - 0.18 11.2 2.5 0.27 10.6 1.7 1.2 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain PCI_Csn8 PF10075.4 EIE91676.1 - 0.011 15.5 0.0 0.014 15.1 0.0 1.1 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 R3H PF01424.17 EIE91676.1 - 0.047 13.3 0.1 0.083 12.5 0.1 1.5 1 0 0 1 1 1 0 R3H domain CPSase_L_D2 PF02786.12 EIE91679.1 - 3.7e-57 193.0 0.0 6.2e-57 192.2 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 EIE91679.1 - 1.7e-38 130.8 0.0 1e-37 128.3 0.0 2.2 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 EIE91679.1 - 5.9e-21 74.6 0.0 1.4e-20 73.3 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_lipoyl PF00364.17 EIE91679.1 - 6.1e-07 28.9 0.0 1.8e-06 27.4 0.0 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 EIE91679.1 - 2.1e-05 24.3 0.0 4.2e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.17 EIE91679.1 - 0.012 14.9 0.1 0.024 14.0 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain Anoctamin PF04547.7 EIE91680.1 - 1e-107 360.6 18.8 1.4e-107 360.2 13.0 1.2 1 0 0 1 1 1 1 Calcium-activated chloride channel SGS PF05002.10 EIE91680.1 - 2.3e-29 100.9 4.8 1e-28 98.9 0.5 2.7 2 0 0 2 2 2 1 SGS domain CS PF04969.11 EIE91680.1 - 2e-18 66.6 0.8 6.8e-18 64.9 0.6 2.0 1 0 0 1 1 1 1 CS domain TPR_11 PF13414.1 EIE91680.1 - 1e-10 41.1 4.2 7.8e-09 35.0 0.6 2.4 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 EIE91680.1 - 3.6e-06 26.4 5.7 0.054 13.4 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EIE91680.1 - 4.1e-06 26.6 3.8 0.00012 21.9 1.6 2.7 2 1 1 3 3 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 EIE91680.1 - 4.5e-05 24.0 6.2 8.3e-05 23.1 0.3 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 EIE91680.1 - 0.0001 22.3 1.2 0.00022 21.2 0.8 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 EIE91680.1 - 0.00012 22.3 3.0 0.0063 16.8 0.0 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 EIE91680.1 - 0.00045 19.6 4.9 0.48 10.1 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 EIE91680.1 - 0.0042 16.9 1.0 0.062 13.1 0.3 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat Plasmid_stab_B PF10784.4 EIE91680.1 - 0.08 12.5 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 Plasmid stability protein TPR_14 PF13428.1 EIE91680.1 - 0.14 12.8 0.7 15 6.5 0.0 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_4 PF07721.9 EIE91680.1 - 0.25 11.9 0.3 1.3 9.6 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 EIE91680.1 - 0.43 10.4 1.9 7.8 6.5 0.0 3.1 2 1 0 2 2 2 0 Tetratricopeptide repeat Pkinase PF00069.20 EIE91682.1 - 8.9e-58 195.4 2.0 1.2e-54 185.1 0.0 3.2 3 1 1 4 4 4 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIE91682.1 - 6.8e-26 90.8 0.0 1.1e-23 83.6 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EIE91682.1 - 2.6e-06 26.6 0.0 4.2e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like KA1 PF02149.14 EIE91682.1 - 5.8e-06 25.6 0.2 1e-05 24.8 0.2 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 RIO1 PF01163.17 EIE91682.1 - 0.00064 19.1 0.1 0.0012 18.2 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 EIE91682.1 - 0.035 13.1 0.1 0.076 12.0 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIE91682.1 - 0.053 13.2 0.0 0.098 12.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Glyco_hydro_72 PF03198.9 EIE91684.1 - 1.2e-130 435.1 0.4 1.5e-130 434.8 0.2 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 EIE91684.1 - 3.1e-10 40.4 0.7 8.9e-10 38.9 0.5 1.7 1 0 0 1 1 1 1 X8 domain Cellulase PF00150.13 EIE91684.1 - 0.0017 17.5 0.1 0.01 15.0 0.1 2.2 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) ATP-synt_ab PF00006.20 EIE91685.1 - 8.7e-64 214.9 0.0 1.8e-63 213.8 0.0 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.18 EIE91685.1 - 4e-25 87.8 2.6 8.1e-25 86.8 1.4 1.9 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain ATP-synt_ab_C PF00306.22 EIE91685.1 - 4.9e-24 84.9 1.3 8.1e-24 84.2 0.9 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain MobB PF03205.9 EIE91685.1 - 0.0024 17.5 0.1 0.94 9.1 0.0 3.1 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 EIE91685.1 - 0.0038 16.9 0.0 0.0076 15.9 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase NACHT PF05729.7 EIE91685.1 - 0.0064 16.1 0.1 0.015 14.9 0.0 1.6 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 EIE91685.1 - 0.012 15.6 0.2 0.046 13.7 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 EIE91685.1 - 0.015 15.4 0.0 0.11 12.5 0.0 2.3 2 1 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EIE91685.1 - 0.019 13.8 1.0 0.033 13.0 0.1 1.7 2 0 0 2 2 2 0 NB-ARC domain KaiC PF06745.8 EIE91685.1 - 0.039 13.0 0.1 0.081 12.0 0.1 1.6 1 0 0 1 1 1 0 KaiC AAA PF00004.24 EIE91685.1 - 0.04 14.1 0.1 0.5 10.5 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EIE91685.1 - 0.041 13.2 0.1 0.15 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 EIE91685.1 - 0.061 12.5 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 RNA_helicase PF00910.17 EIE91685.1 - 0.12 12.5 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase ATP-synt_DE_N PF02823.11 EIE91686.1 - 1.1e-19 69.9 0.3 1.9e-19 69.2 0.2 1.4 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Pcc1 PF09341.5 EIE91687.1 - 4.2e-23 81.1 0.6 4.6e-23 81.0 0.4 1.0 1 0 0 1 1 1 1 Transcription factor Pcc1 Streptin-Immun PF11083.3 EIE91687.1 - 0.11 12.4 0.1 0.13 12.2 0.1 1.2 1 0 0 1 1 1 0 Lantibiotic streptin immunity protein PGI PF00342.14 EIE91688.1 - 8.3e-233 773.1 0.2 9.5e-233 772.9 0.2 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase MAF_flag10 PF01973.13 EIE91688.1 - 0.024 14.1 0.0 0.051 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF115 DDE_3 PF13358.1 EIE91689.1 - 2e-21 76.2 0.1 2.4e-21 76.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE91689.1 - 0.0052 16.8 0.0 0.0085 16.2 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain DUF3883 PF13020.1 EIE91689.1 - 0.13 12.0 0.2 0.28 10.9 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3883) Ribosomal_60s PF00428.14 EIE91690.1 - 2.1e-25 88.9 11.5 2.4e-25 88.7 7.9 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Attacin_N PF03768.10 EIE91690.1 - 0.19 11.6 1.7 0.3 10.9 1.2 1.4 1 1 0 1 1 1 0 Attacin, N-terminal region Oxysterol_BP PF01237.13 EIE91691.1 - 3.7e-15 55.2 2.2 4.2e-15 55.0 1.5 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein Oxysterol_BP PF01237.13 EIE91692.1 - 2.9e-51 174.0 0.0 3.5e-51 173.7 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein RasGEF PF00617.14 EIE91693.1 - 3.1e-59 199.8 0.2 7.8e-59 198.5 0.1 1.7 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EIE91693.1 - 4.1e-25 87.9 0.7 4.1e-25 87.9 0.5 3.0 2 0 0 2 2 2 1 RasGEF N-terminal motif SH3_1 PF00018.23 EIE91693.1 - 1.4e-12 46.8 0.6 3.2e-12 45.6 0.4 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EIE91693.1 - 4.2e-12 45.4 0.7 1e-11 44.2 0.5 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EIE91693.1 - 4.5e-08 32.4 0.1 1e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.21 EIE91693.1 - 1.2e-06 28.2 12.8 0.00016 21.4 4.7 2.8 2 0 0 2 2 2 2 WW domain CDC45 PF02724.9 EIE91693.1 - 1 7.3 29.2 0.0049 14.9 2.3 3.2 3 0 0 3 3 3 0 CDC45-like protein DUF3655 PF12379.3 EIE91695.1 - 0.11 12.4 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3655) ECH_C PF13766.1 EIE91698.1 - 0.089 12.9 0.0 0.093 12.8 0.0 1.0 1 0 0 1 1 1 0 2-enoyl-CoA Hydratase C-terminal region Svf1 PF08622.5 EIE91699.1 - 7.4e-89 297.9 7.4 9.6e-89 297.5 5.2 1.1 1 0 0 1 1 1 1 Svf1-like SWIRM PF04433.12 EIE91700.1 - 1.9e-10 40.7 0.0 1.4e-09 37.9 0.0 2.2 2 0 0 2 2 2 1 SWIRM domain DUF663 PF04950.7 EIE91701.1 - 1e-90 303.7 0.0 1e-90 303.7 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EIE91702.1 - 1.9e-29 101.0 0.0 3.3e-29 100.2 0.0 1.4 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 EIE91702.1 - 1.8e-08 34.0 0.0 3.9e-05 23.1 0.0 2.3 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain AAA_17 PF13207.1 EIE91702.1 - 4e-07 30.8 0.0 7.8e-07 29.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EIE91702.1 - 3.2e-06 27.2 0.0 5.2e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 EIE91702.1 - 4.9e-06 26.4 0.0 9.4e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EIE91702.1 - 1.7e-05 24.9 0.0 6.6e-05 23.0 0.0 2.0 2 0 0 2 2 1 1 AAA domain Miro PF08477.8 EIE91702.1 - 3.2e-05 24.3 0.0 9e-05 22.9 0.0 1.8 2 0 0 2 2 1 1 Miro-like protein MobB PF03205.9 EIE91702.1 - 4.5e-05 23.1 0.2 0.00025 20.7 0.0 2.0 1 1 1 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 EIE91702.1 - 5.1e-05 23.1 0.2 0.00027 20.8 0.2 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.1 EIE91702.1 - 7.3e-05 23.0 0.2 0.00027 21.2 0.2 2.2 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 EIE91702.1 - 0.00015 22.0 0.0 0.00032 20.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 EIE91702.1 - 0.00027 21.2 0.0 0.00061 20.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter Zeta_toxin PF06414.7 EIE91702.1 - 0.00031 19.9 0.0 0.00057 19.0 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_10 PF12846.2 EIE91702.1 - 0.00046 19.7 0.0 0.00065 19.2 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain PduV-EutP PF10662.4 EIE91702.1 - 0.00083 18.8 0.0 0.0032 16.9 0.0 1.9 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.17 EIE91702.1 - 0.0012 19.0 0.0 0.0056 16.8 0.0 2.1 2 0 0 2 2 2 1 RNA helicase NACHT PF05729.7 EIE91702.1 - 0.0013 18.4 0.0 0.0024 17.5 0.0 1.4 1 1 0 1 1 1 1 NACHT domain cobW PF02492.14 EIE91702.1 - 0.002 17.6 0.1 0.0041 16.5 0.0 1.5 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.1 EIE91702.1 - 0.0025 17.5 0.0 0.0051 16.5 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain Viral_helicase1 PF01443.13 EIE91702.1 - 0.0033 16.9 0.0 0.0066 15.9 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_28 PF13521.1 EIE91702.1 - 0.0062 16.5 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain Dynamin_N PF00350.18 EIE91702.1 - 0.0068 16.2 0.7 0.063 13.0 0.0 2.4 2 1 1 3 3 2 1 Dynamin family NTPase_1 PF03266.10 EIE91702.1 - 0.0068 16.1 0.1 0.012 15.3 0.1 1.3 1 0 0 1 1 1 1 NTPase ATP_bind_1 PF03029.12 EIE91702.1 - 0.015 14.8 0.0 0.027 14.0 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_14 PF13173.1 EIE91702.1 - 0.015 15.1 0.0 0.03 14.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EIE91702.1 - 0.018 14.5 0.0 0.037 13.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ArgK PF03308.11 EIE91702.1 - 0.019 13.7 0.1 0.056 12.2 0.0 1.7 2 0 0 2 2 2 0 ArgK protein AAA_5 PF07728.9 EIE91702.1 - 0.025 14.2 0.0 0.055 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Adeno_IVa2 PF02456.10 EIE91702.1 - 0.028 13.0 0.0 0.038 12.6 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein Arch_ATPase PF01637.13 EIE91702.1 - 0.031 13.9 0.7 0.043 13.5 0.0 1.7 2 0 0 2 2 1 0 Archaeal ATPase AAA_25 PF13481.1 EIE91702.1 - 0.032 13.6 0.0 0.055 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.9 EIE91702.1 - 0.037 13.0 0.0 0.037 13.0 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain FtsK_SpoIIIE PF01580.13 EIE91702.1 - 0.042 13.3 0.0 0.075 12.4 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF815 PF05673.8 EIE91702.1 - 0.054 12.4 0.0 0.08 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PRK PF00485.13 EIE91702.1 - 0.054 13.0 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family DUF258 PF03193.11 EIE91702.1 - 0.056 12.6 0.0 0.095 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_21 PF13304.1 EIE91702.1 - 0.086 12.7 0.2 0.13 12.1 0.1 1.5 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EIE91702.1 - 0.087 11.6 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_30 PF13604.1 EIE91702.1 - 0.094 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.12 EIE91702.1 - 0.096 12.4 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF87 SRP54 PF00448.17 EIE91702.1 - 0.1 12.0 0.0 0.3 10.5 0.0 1.8 2 0 0 2 2 1 0 SRP54-type protein, GTPase domain Septin PF00735.13 EIE91702.1 - 0.11 11.4 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Septin RNA12 PF10443.4 EIE91702.1 - 0.14 10.5 0.0 0.22 9.9 0.0 1.2 1 0 0 1 1 1 0 RNA12 protein T2SE PF00437.15 EIE91702.1 - 0.17 10.7 0.0 0.25 10.2 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Peroxin-22 PF12827.2 EIE91703.1 - 0.0069 16.0 1.4 0.047 13.4 0.9 2.0 1 1 0 1 1 1 1 Peroxisomal biogenesis protein family Asp PF00026.18 EIE91704.1 - 5.5e-72 242.6 3.6 7.9e-72 242.1 2.5 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIE91704.1 - 8.8e-11 42.0 0.6 1.4e-08 34.8 0.3 3.3 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal RVP PF00077.15 EIE91704.1 - 0.0065 16.3 0.1 3.3 7.6 0.0 2.5 2 0 0 2 2 2 2 Retroviral aspartyl protease Asp_protease_2 PF13650.1 EIE91704.1 - 0.016 15.7 1.6 2.4 8.7 0.0 3.4 2 1 0 2 2 2 0 Aspartyl protease zf-CCHC PF00098.18 EIE91706.1 - 8e-07 28.6 2.2 1.3e-06 28.0 1.5 1.3 1 0 0 1 1 1 1 Zinc knuckle Asp_protease_2 PF13650.1 EIE91706.1 - 0.0019 18.6 0.0 0.0043 17.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC_4 PF14392.1 EIE91706.1 - 0.012 15.2 2.1 0.043 13.4 1.2 2.0 2 0 0 2 2 2 0 Zinc knuckle gag-asp_proteas PF13975.1 EIE91706.1 - 0.036 13.8 0.0 0.078 12.8 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DDE_3 PF13358.1 EIE91707.1 - 7.9e-18 64.6 0.2 1.4e-17 63.8 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE91707.1 - 2.1e-05 24.5 0.2 2.1e-05 24.5 0.1 2.1 3 0 0 3 3 3 1 Transposase HTH_23 PF13384.1 EIE91707.1 - 0.017 14.7 1.0 0.14 11.8 0.0 2.8 3 0 0 3 3 3 0 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.1 EIE91707.1 - 0.098 11.8 0.8 0.24 10.6 0.2 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 DDE_3 PF13358.1 EIE91709.1 - 1.6e-17 63.6 0.1 2.7e-17 62.8 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE91709.1 - 1.1e-10 41.3 0.8 2.2e-10 40.4 0.3 1.7 2 0 0 2 2 2 1 Transposase HTH_Tnp_Tc3_2 PF01498.13 EIE91710.1 - 6.2e-09 35.7 0.5 3.2e-08 33.4 0.4 2.2 2 1 1 3 3 3 1 Transposase DDE_3 PF13358.1 EIE91710.1 - 1.3e-06 28.2 0.0 2.7e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease FliJ PF02050.11 EIE91711.1 - 0.019 15.0 0.9 0.021 14.8 0.6 1.1 1 0 0 1 1 1 0 Flagellar FliJ protein Mvb12 PF09452.5 EIE91711.1 - 0.12 12.5 0.9 0.15 12.2 0.6 1.3 1 1 0 1 1 1 0 ESCRT-I subunit Mvb12 rve PF00665.21 EIE91712.1 - 4.1e-27 94.6 0.0 6.8e-27 93.9 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 EIE91712.1 - 2.3e-05 23.8 0.0 5.3e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE91713.1 - 4.3e-10 39.3 0.0 1e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease PF09668.5 EIE91713.1 - 0.00024 20.6 0.0 0.00045 19.7 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 EIE91713.1 - 0.0054 17.2 0.0 0.013 15.9 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.6 EIE91713.1 - 0.014 15.3 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease AMIN PF11741.3 EIE91713.1 - 0.2 11.6 4.1 5.6 7.0 0.0 4.2 4 1 1 5 5 5 0 AMIN domain DUF1759 PF03564.10 EIE91714.1 - 0.0023 17.7 0.3 0.0023 17.7 0.2 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1759) HTH_Tnp_Tc3_2 PF01498.13 EIE91715.1 - 4e-10 39.5 3.2 1.8e-09 37.5 0.9 2.2 2 0 0 2 2 2 1 Transposase HTH_11 PF08279.7 EIE91715.1 - 0.00019 20.9 0.0 0.0005 19.6 0.0 1.6 1 0 0 1 1 1 1 HTH domain HTH_23 PF13384.1 EIE91715.1 - 0.00024 20.6 0.1 0.00059 19.3 0.0 1.6 2 0 0 2 2 1 1 Homeodomain-like domain HTH_IclR PF09339.5 EIE91715.1 - 0.00032 20.2 0.0 0.00069 19.1 0.0 1.6 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_7 PF02796.10 EIE91715.1 - 0.00044 20.0 0.3 0.012 15.5 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_32 PF13565.1 EIE91715.1 - 0.00075 20.2 1.1 0.9 10.3 0.1 2.5 2 1 0 2 2 2 2 Homeodomain-like domain HTH_38 PF13936.1 EIE91715.1 - 0.0016 17.9 0.0 0.0035 16.8 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.1 EIE91715.1 - 0.0034 17.5 0.2 0.034 14.3 0.0 2.0 2 0 0 2 2 2 1 Winged helix-turn helix Sigma70_r4_2 PF08281.7 EIE91715.1 - 0.0047 16.3 0.0 0.0091 15.4 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_36 PF13730.1 EIE91715.1 - 0.0083 16.2 0.0 0.1 12.7 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_24 PF13412.1 EIE91715.1 - 0.011 15.1 0.0 0.024 14.0 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Sigma70_r4 PF04545.11 EIE91715.1 - 0.013 14.8 0.0 0.025 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_AsnC-type PF13404.1 EIE91715.1 - 0.017 14.6 0.0 0.03 13.8 0.0 1.4 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_17 PF12728.2 EIE91715.1 - 0.021 15.0 0.0 0.039 14.1 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain GerE PF00196.14 EIE91715.1 - 0.023 14.0 0.0 0.045 13.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family UPF0122 PF04297.9 EIE91715.1 - 0.029 14.3 0.1 0.053 13.5 0.0 1.4 1 0 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like Terminase_5 PF06056.7 EIE91715.1 - 0.042 13.4 0.0 0.086 12.4 0.0 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) HTH_Tnp_4 PF13613.1 EIE91715.1 - 0.054 13.0 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_6 PF01418.12 EIE91715.1 - 0.069 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family HTH_Crp_2 PF13545.1 EIE91715.1 - 0.074 12.8 0.0 0.23 11.2 0.0 1.7 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain Trp_repressor PF01371.14 EIE91715.1 - 0.075 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Trp repressor protein HTH_28 PF13518.1 EIE91715.1 - 0.1 12.6 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain DUF603 PF04645.7 EIE91715.1 - 0.1 12.5 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF603 HTH_22 PF13309.1 EIE91715.1 - 0.11 12.3 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 HTH domain MarR_2 PF12802.2 EIE91715.1 - 0.11 12.1 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 MarR family DUF658 PF04936.7 EIE91715.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF658) HTH_31 PF13560.1 EIE91715.1 - 0.13 12.5 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain DDE_3 PF13358.1 EIE91717.1 - 1.3e-24 86.5 0.2 2.7e-24 85.5 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease rve PF00665.21 EIE91717.1 - 0.00025 21.1 0.0 0.00049 20.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain HTH_Tnp_Tc3_2 PF01498.13 EIE91718.1 - 1.8e-10 40.7 2.2 2e-10 40.5 0.7 1.7 2 0 0 2 2 2 1 Transposase Imm37 PF15598.1 EIE91718.1 - 0.1 12.4 0.2 0.15 11.9 0.2 1.3 1 0 0 1 1 1 0 Immunity protein 37 HTH_Tnp_Tc3_2 PF01498.13 EIE91719.1 - 1.8e-08 34.3 2.0 3.1e-08 33.5 0.1 2.0 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 EIE91719.1 - 0.0039 17.3 2.8 0.6 10.2 0.3 2.3 1 1 1 2 2 2 2 Winged helix-turn helix HTH_Tnp_ISL3 PF13542.1 EIE91719.1 - 0.0061 15.7 2.0 0.021 13.9 0.5 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_21 PF13276.1 EIE91719.1 - 0.062 13.3 1.7 0.6 10.1 0.0 2.3 2 0 0 2 2 2 0 HTH-like domain HTH_12 PF08461.5 EIE91719.1 - 0.063 13.0 0.1 0.18 11.5 0.1 1.7 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain DUF4330 PF14221.1 EIE91719.1 - 0.082 12.7 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4330) HTH_23 PF13384.1 EIE91719.1 - 0.11 12.1 2.9 1.6 8.5 0.2 2.4 2 0 0 2 2 2 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.13 EIE91720.1 - 6e-08 32.6 1.5 1.2e-07 31.6 0.8 1.7 2 0 0 2 2 2 1 Transposase DUF3460 PF11943.3 EIE91720.1 - 0.092 12.8 0.2 0.19 11.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3460) RVT_1 PF00078.22 EIE91721.1 - 6.6e-15 55.0 0.0 1.1e-14 54.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ATP-synt_D PF01813.12 EIE91722.1 - 6e-66 221.7 4.7 7.7e-66 221.3 3.2 1.1 1 0 0 1 1 1 1 ATP synthase subunit D Herpes_gE PF02480.11 EIE91723.1 - 0.00061 18.1 0.1 0.014 13.6 0.0 2.0 1 1 1 2 2 2 1 Alphaherpesvirus glycoprotein E Mid2 PF04478.7 EIE91723.1 - 0.0026 17.1 4.5 0.0026 17.1 3.1 1.8 1 1 1 2 2 2 1 Mid2 like cell wall stress sensor Adeno_E3_CR2 PF02439.10 EIE91723.1 - 0.12 11.9 0.1 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 SKG6 PF08693.5 EIE91723.1 - 0.32 10.3 0.1 0.32 10.3 0.1 1.9 2 0 0 2 2 2 0 Transmembrane alpha-helix domain TMEM154 PF15102.1 EIE91723.1 - 0.55 9.9 12.0 0.054 13.1 1.0 2.1 1 1 1 2 2 2 0 TMEM154 protein family PDGLE PF13190.1 EIE91723.1 - 0.62 9.7 5.2 1.4 8.6 3.6 1.6 1 1 0 1 1 1 0 PDGLE domain Gly-zipper_Omp PF13488.1 EIE91723.1 - 1.5 8.5 10.1 2.9 7.6 7.0 1.4 1 1 0 1 1 1 0 Glycine zipper DUF3824 PF12868.2 EIE91723.1 - 5.3 7.9 9.7 1.1 10.1 4.0 1.8 2 1 0 2 2 2 0 Domain of unknwon function (DUF3824) DUF4271 PF14093.1 EIE91725.1 - 0.0063 16.2 5.6 0.0063 16.2 3.9 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4271) DUF4212 PF13937.1 EIE91725.1 - 0.034 14.1 1.7 0.034 14.1 1.2 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4212) DUF4134 PF13572.1 EIE91725.1 - 0.11 12.6 10.1 2.3 8.4 1.4 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4134) Bac_export_2 PF01312.14 EIE91725.1 - 0.49 9.2 3.8 0.21 10.4 0.8 1.5 1 1 0 1 1 1 0 FlhB HrpN YscU SpaS Family Kei1 PF08552.6 EIE91725.1 - 1.3 8.6 11.5 0.67 9.5 0.7 2.2 1 1 1 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 CoA_binding_3 PF13727.1 EIE91725.1 - 1.6 8.5 8.7 0.12 12.1 2.5 1.8 2 0 0 2 2 2 0 CoA-binding domain YjgP_YjgQ PF03739.9 EIE91725.1 - 2.4 6.7 11.4 1.2 7.8 0.1 2.2 2 0 0 2 2 2 0 Predicted permease YjgP/YjgQ family Cation_ATPase_C PF00689.16 EIE91725.1 - 4.1 6.8 14.5 12 5.3 9.9 1.7 1 1 1 2 2 2 0 Cation transporting ATPase, C-terminus Abhydrolase_9_N PF15420.1 EIE91725.1 - 4.4 7.0 9.2 1.8 8.2 4.7 1.6 1 1 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus DUF1980 PF09323.5 EIE91725.1 - 5.3 6.7 11.1 0.4 10.3 2.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1980) Terminase_4 PF05119.7 EIE91726.1 - 0.074 13.2 0.0 0.077 13.1 0.0 1.2 1 0 0 1 1 1 0 Phage terminase, small subunit Pkinase_Tyr PF07714.12 EIE91727.1 - 3.2e-24 85.3 0.0 4.2e-24 85.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EIE91727.1 - 1.6e-22 79.9 0.0 2.5e-22 79.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain PP2C PF00481.16 EIE91728.1 - 1.3e-31 109.8 0.0 1.6e-30 106.3 0.0 2.4 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EIE91728.1 - 0.00027 20.4 0.0 0.0005 19.5 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C DUF3990 PF13151.1 EIE91728.1 - 0.1 11.9 0.0 0.24 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3990) adh_short PF00106.20 EIE91729.1 - 4.4e-32 111.2 0.1 6e-32 110.8 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIE91729.1 - 1.5e-25 90.4 0.0 2e-25 89.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIE91729.1 - 1.2e-11 44.6 0.1 1.7e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EIE91729.1 - 0.00018 21.0 0.0 0.00033 20.1 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIE91729.1 - 0.0071 16.3 0.0 0.0095 15.9 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 EIE91729.1 - 0.075 12.1 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.3 EIE91729.1 - 0.21 11.4 1.1 0.75 9.6 0.5 2.0 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Ribosomal_L18e PF00828.14 EIE91730.1 - 1.9e-24 86.4 0.1 2.1e-24 86.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 HTH_32 PF13565.1 EIE91731.1 - 0.00048 20.8 0.2 0.0022 18.7 0.0 2.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_29 PF13551.1 EIE91731.1 - 0.024 14.7 0.0 0.081 13.0 0.0 2.0 1 1 1 2 2 2 0 Winged helix-turn helix DDE_3 PF13358.1 EIE91732.1 - 9e-21 74.1 0.0 1.2e-20 73.7 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE91732.1 - 0.00073 19.6 0.0 0.00094 19.2 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain DDE_1 PF03184.14 EIE91732.1 - 0.0078 15.3 0.0 0.0094 15.1 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_ISAZ013 PF07592.6 EIE91732.1 - 0.053 12.2 0.0 0.059 12.1 0.0 1.1 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain Histone PF00125.19 EIE91733.1 - 4.4e-15 55.5 0.2 5.3e-15 55.3 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EIE91733.1 - 2.1e-05 24.5 0.1 3.5e-05 23.9 0.1 1.5 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 EIE91733.1 - 4.5e-05 23.3 0.1 6.3e-05 22.8 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 EIE91733.1 - 0.00013 21.9 0.1 0.00023 21.1 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 EIE91733.1 - 0.012 14.9 0.0 0.012 14.9 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 EIE91733.1 - 0.043 13.5 0.0 0.068 12.9 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.8 EIE91733.1 - 0.11 12.7 0.1 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Histone PF00125.19 EIE91734.1 - 1.4e-31 108.4 0.4 2.1e-31 107.8 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EIE91734.1 - 1.2e-05 25.3 0.0 1.8e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EIE91734.1 - 0.0061 16.6 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 EIE91734.1 - 0.014 14.6 1.1 0.023 13.9 0.8 1.5 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 EIE91734.1 - 0.019 14.6 0.1 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.19 EIE91735.1 - 1.2e-25 89.4 0.0 1.5e-25 89.0 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EIE91735.1 - 2.4e-05 24.3 0.0 3.2e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EIE91736.1 - 4.4e-24 84.3 0.5 7e-24 83.7 0.3 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EIE91736.1 - 6.7e-07 29.2 1.6 1.5e-06 28.1 0.0 2.1 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 EIE91736.1 - 0.00016 21.9 0.0 0.00027 21.1 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Mitofilin PF09731.4 EIE91736.1 - 0.032 12.9 0.8 0.036 12.7 0.6 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF1018 PF06252.7 EIE91736.1 - 0.085 13.3 0.2 0.11 13.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) RP-C PF03428.8 EIE91736.1 - 0.15 11.5 0.7 0.48 9.8 0.5 1.8 1 1 0 1 1 1 0 Replication protein C N-terminal domain TAF PF02969.12 EIE91736.1 - 0.27 11.2 1.2 0.38 10.7 0.0 1.8 2 0 0 2 2 2 0 TATA box binding protein associated factor (TAF) RRM_6 PF14259.1 EIE91737.1 - 1.1e-13 50.9 0.1 1.5e-13 50.4 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EIE91737.1 - 1.1e-09 37.7 0.1 1.9e-09 37.0 0.1 1.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RanBP PF00641.13 EIE91737.1 - 0.0002 20.4 2.4 0.0003 19.8 1.7 1.2 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others A2L_zn_ribbon PF08792.5 EIE91737.1 - 0.017 14.5 2.7 0.04 13.3 1.8 1.6 1 1 0 1 1 1 0 A2L zinc ribbon domain DZR PF12773.2 EIE91737.1 - 0.019 14.7 0.6 0.028 14.2 0.4 1.3 1 0 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.1 EIE91737.1 - 0.02 14.0 0.4 0.033 13.4 0.3 1.3 1 0 0 1 1 1 0 zinc-ribbon domain Tnp_zf-ribbon_2 PF13842.1 EIE91737.1 - 0.033 14.6 3.5 0.46 10.9 0.8 2.3 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon ZF-HD_dimer PF04770.7 EIE91737.1 - 1.5 8.9 5.3 0.53 10.3 1.4 1.9 1 1 1 2 2 2 0 ZF-HD protein dimerisation region Cwf_Cwc_15 PF04889.7 EIE91738.1 - 8.4e-70 235.2 31.2 9.7e-70 235.0 21.6 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Bd3614_N PF14442.1 EIE91738.1 - 0.23 11.4 8.5 0.44 10.5 5.9 1.5 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal CDC27 PF09507.5 EIE91738.1 - 0.74 8.9 24.9 0.87 8.7 17.3 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SprA-related PF12118.3 EIE91738.1 - 1.3 8.2 18.9 1.6 7.9 13.1 1.2 1 0 0 1 1 1 0 SprA-related family Daxx PF03344.10 EIE91738.1 - 2.3 6.5 30.0 2.8 6.3 20.8 1.1 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 EIE91738.1 - 2.4 6.1 24.2 2.7 5.9 16.7 1.1 1 0 0 1 1 1 0 CDC45-like protein SAPS PF04499.10 EIE91738.1 - 3.2 6.2 13.2 4.7 5.7 9.2 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Ebola_NP PF05505.7 EIE91738.1 - 3.5 5.5 14.5 4.3 5.2 10.1 1.2 1 0 0 1 1 1 0 Ebola nucleoprotein Arrestin_C PF02752.17 EIE91739.1 - 1e-10 41.8 1.3 1.3e-09 38.3 0.0 2.6 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EIE91739.1 - 5.4e-06 26.2 0.2 0.058 13.2 0.1 2.9 2 1 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Rgp1 PF08737.5 EIE91739.1 - 2.3e-05 23.6 0.5 0.00078 18.6 0.1 2.3 2 0 0 2 2 2 2 Rgp1 Ribosomal_L11 PF00298.14 EIE91740.1 - 3.3e-29 100.8 2.0 3.3e-29 100.8 1.4 1.5 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.9 EIE91740.1 - 1e-26 92.1 0.3 1.6e-26 91.5 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain TrbC_Ftype PF09673.5 EIE91740.1 - 0.029 13.9 0.0 0.042 13.4 0.0 1.2 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein DUF1767 PF08585.7 EIE91741.1 - 0.13 12.5 1.2 1.6 9.0 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1767) Pkinase PF00069.20 EIE91742.1 - 1.1e-63 214.8 0.0 1.7e-63 214.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE91742.1 - 8.1e-34 116.8 0.0 1.3e-33 116.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE91742.1 - 0.029 13.3 0.0 0.061 12.2 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 EIE91742.1 - 0.054 12.5 0.1 0.088 11.8 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC1 PF03109.11 EIE91742.1 - 0.068 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 ABC1 family ArsB PF02040.10 EIE91743.1 - 3.8e-26 92.0 37.6 7e-15 54.9 15.0 2.1 2 0 0 2 2 2 2 Arsenical pump membrane protein CitMHS PF03600.11 EIE91743.1 - 5.3e-14 51.5 37.8 1.1e-12 47.2 14.4 3.4 3 1 0 3 3 3 3 Citrate transporter p450 PF00067.17 EIE91745.1 - 1.5e-46 158.9 0.1 4e-40 137.7 0.1 2.0 1 1 1 2 2 2 2 Cytochrome P450 tRNA-synt_2 PF00152.15 EIE91746.1 - 1.3e-76 257.5 0.1 1.3e-76 257.5 0.1 1.8 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EIE91746.1 - 1.2e-09 37.8 0.0 2.5e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti-like PF12869.2 EIE91746.1 - 0.016 14.6 2.3 0.09 12.2 1.6 2.1 1 1 0 1 1 1 0 tRNA_anti-like Mo25 PF08569.6 EIE91746.1 - 0.05 12.6 4.1 0.084 11.8 2.8 1.2 1 0 0 1 1 1 0 Mo25-like V_ATPase_I PF01496.14 EIE91746.1 - 0.091 10.6 3.9 0.13 10.1 2.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Stn1 PF10451.4 EIE91746.1 - 0.1 11.4 0.0 0.1 11.4 0.0 2.0 2 0 0 2 2 2 0 Telomere regulation protein Stn1 zf-C2H2 PF00096.21 EIE91747.1 - 2.7e-10 39.9 13.1 7.5e-05 22.8 1.6 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIE91747.1 - 1.1e-07 31.6 13.4 0.00017 21.6 1.8 2.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EIE91747.1 - 1.2e-07 31.6 22.3 7.5e-06 25.9 4.5 3.4 3 1 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.2 EIE91747.1 - 0.035 14.3 0.7 4.7 7.5 0.2 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DUF2225 PF09986.4 EIE91747.1 - 0.13 11.7 0.5 0.18 11.2 0.4 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-C2H2_jaz PF12171.3 EIE91747.1 - 0.38 10.9 5.7 2.4 8.4 0.2 2.7 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EIE91747.1 - 5.8 6.9 9.6 3.9 7.5 0.1 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger CytochromB561_N PF09786.4 EIE91748.1 - 0.0005 18.6 0.0 0.00066 18.2 0.0 1.4 1 0 0 1 1 1 1 Cytochrome B561, N terminal Spindle_Spc25 PF08234.7 EIE91748.1 - 0.031 14.2 0.0 0.061 13.3 0.0 1.5 1 0 0 1 1 1 0 Chromosome segregation protein Spc25 DUF4556 PF15094.1 EIE91748.1 - 0.083 12.4 0.0 0.16 11.4 0.0 1.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4556) PAH PF02671.16 EIE91749.1 - 3.9e-44 148.0 4.4 6.4e-19 67.2 0.4 4.0 3 0 0 3 3 3 3 Paired amphipathic helix repeat Peptidase_M24 PF00557.19 EIE91749.1 - 4.4e-41 140.7 0.0 8.6e-41 139.7 0.0 1.5 1 0 0 1 1 1 1 Metallopeptidase family M24 Sin3_corepress PF08295.7 EIE91749.1 - 4.1e-38 129.2 0.3 1.2e-37 127.7 0.2 1.9 1 0 0 1 1 1 1 Sin3 family co-repressor Creatinase_N PF01321.13 EIE91749.1 - 3.9e-24 85.6 0.0 3.9e-20 72.6 0.0 2.6 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain ESCRT-II PF05871.7 EIE91750.1 - 7.2e-38 129.6 2.9 8.2e-38 129.4 2.0 1.0 1 0 0 1 1 1 1 ESCRT-II complex subunit RNase_T PF00929.19 EIE91751.1 - 3e-20 73.1 0.6 6.2e-20 72.1 0.1 1.8 2 0 0 2 2 2 1 Exonuclease DUF2387 PF09526.5 EIE91751.1 - 2.2 8.2 7.2 11 5.9 0.1 2.8 3 0 0 3 3 3 0 Probable metal-binding protein (DUF2387) An_peroxidase PF03098.10 EIE91752.1 - 7.8e-52 176.3 0.0 1.1e-51 175.8 0.0 1.1 1 0 0 1 1 1 1 Animal haem peroxidase Lon_2 PF13337.1 EIE91752.1 - 0.12 10.6 0.0 0.21 9.8 0.0 1.4 2 0 0 2 2 2 0 Putative ATP-dependent Lon protease PGG PF13962.1 EIE91753.1 - 0.012 15.1 0.6 0.019 14.6 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF202 PF02656.10 EIE91753.1 - 0.48 10.6 2.4 3.4 7.9 1.7 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF202) SH2_2 PF14633.1 EIE91754.1 - 4e-63 212.4 0.0 4e-63 212.4 0.0 2.3 2 0 0 2 2 2 1 SH2 domain YqgF PF14639.1 EIE91754.1 - 2e-35 121.5 0.1 6.2e-35 119.9 0.1 1.9 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 DLD PF14878.1 EIE91754.1 - 2.9e-31 107.9 1.4 2.9e-31 107.9 1.0 4.0 3 1 0 3 3 3 1 Death-like domain of SPT6 HHH_7 PF14635.1 EIE91754.1 - 6.3e-28 96.9 0.0 1.6e-27 95.6 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif HTH_44 PF14641.1 EIE91754.1 - 3.4e-19 69.0 1.3 3.4e-19 69.0 0.9 2.4 2 0 0 2 2 2 1 Helix-turn-helix DNA-binding domain of SPT6 SPT6_acidic PF14632.1 EIE91754.1 - 1.1e-18 67.1 27.5 1.1e-18 67.1 19.1 5.4 4 1 1 5 5 5 1 Acidic N-terminal SPT6 SH2 PF00017.19 EIE91754.1 - 3.4e-07 29.9 0.0 1.3e-06 28.1 0.0 2.1 2 0 0 2 2 2 1 SH2 domain HHH_3 PF12836.2 EIE91754.1 - 1.7e-05 24.6 0.0 4.6e-05 23.2 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif S1 PF00575.18 EIE91754.1 - 3.2e-05 23.9 0.1 9.9e-05 22.3 0.1 1.9 1 0 0 1 1 1 1 S1 RNA binding domain Methyltransf_11 PF08241.7 EIE91756.1 - 6.6e-08 32.9 0.0 1.3e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIE91756.1 - 1.8e-07 31.0 0.1 2.3e-07 30.6 0.1 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIE91756.1 - 2.8e-07 30.2 0.0 4.3e-07 29.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIE91756.1 - 3.4e-07 30.6 0.1 7e-07 29.6 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIE91756.1 - 9.6e-07 29.3 0.0 1.6e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EIE91756.1 - 4.9e-05 22.5 0.0 5.4e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.13 EIE91756.1 - 0.01 14.9 0.0 0.061 12.4 0.0 1.9 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EIE91756.1 - 0.022 14.7 0.0 0.038 14.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.1 EIE91756.1 - 0.044 14.6 0.0 0.078 13.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF1043 PF06295.7 EIE91756.1 - 0.092 12.3 0.2 0.19 11.3 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) PHD PF00628.24 EIE91757.1 - 1.3e-06 27.9 14.1 1.8e-06 27.5 9.0 1.9 2 0 0 2 2 2 1 PHD-finger DUF4530 PF15039.1 EIE91757.1 - 0.011 15.6 0.4 0.041 13.7 0.3 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4530) Menin PF05053.8 EIE91757.1 - 0.24 9.5 15.2 0.14 10.2 9.5 1.3 1 1 0 1 1 1 0 Menin PHD_2 PF13831.1 EIE91757.1 - 0.43 9.9 11.7 0.81 9.0 8.1 1.5 1 0 0 1 1 1 0 PHD-finger ACBP PF00887.14 EIE91759.1 - 0.00014 21.5 0.2 0.00034 20.2 0.2 1.7 1 0 0 1 1 1 1 Acyl CoA binding protein DUF4611 PF15387.1 EIE91759.1 - 0.015 15.4 1.9 1.9 8.6 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) Pkinase PF00069.20 EIE91760.1 - 2.2e-34 118.8 0.0 3e-34 118.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE91760.1 - 3.7e-11 42.5 0.0 5.7e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase CYSTM PF12734.2 EIE91760.1 - 0.0032 17.5 0.1 0.0073 16.3 0.0 1.6 1 0 0 1 1 1 1 Cysteine-rich TM module stress tolerance Kdo PF06293.9 EIE91760.1 - 0.015 14.3 0.0 0.049 12.6 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EIE91760.1 - 0.019 14.3 0.0 0.038 13.3 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.18 EIE91760.1 - 0.13 11.9 0.0 4.4 6.9 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Metallophos_2 PF12850.2 EIE91761.1 - 2.4e-06 27.4 0.0 3.8e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EIE91761.1 - 0.00047 19.6 0.3 0.56 9.5 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase RGS PF00615.14 EIE91762.1 - 1.8e-10 40.9 0.1 2.9e-10 40.2 0.1 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain Pkinase PF00069.20 EIE91763.1 - 2.2e-68 230.2 0.0 2.7e-68 229.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE91763.1 - 1.6e-35 122.4 0.0 2.2e-35 121.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE91763.1 - 3.9e-05 22.7 0.0 7.9e-05 21.7 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 EIE91763.1 - 0.009 15.7 0.0 0.023 14.4 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EIE91763.1 - 0.069 12.2 0.0 0.15 11.1 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EI24 PF07264.6 EIE91764.1 - 2.5e-09 36.8 16.5 2.7e-09 36.7 10.8 1.4 1 1 1 2 2 2 1 Etoposide-induced protein 2.4 (EI24) DUF2079 PF09852.4 EIE91764.1 - 0.0007 18.4 15.4 0.0013 17.5 10.7 1.3 1 1 0 1 1 1 1 Predicted membrane protein (DUF2079) Mog1 PF04603.7 EIE91765.1 - 9.7e-19 67.7 0.1 1.1e-18 67.4 0.1 1.0 1 0 0 1 1 1 1 Ran-interacting Mog1 protein Ribosomal_L13 PF00572.13 EIE91766.1 - 5.9e-50 168.6 0.2 7.2e-50 168.3 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L13 DUF2340 PF10209.4 EIE91766.1 - 0.12 12.5 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2340) EXOSC1 PF10447.4 EIE91768.1 - 2.1e-25 88.4 1.0 3.1e-25 87.9 0.7 1.3 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.1 EIE91768.1 - 5e-13 48.0 0.4 5e-13 48.0 0.3 2.3 3 0 0 3 3 3 1 Exosome complex exonuclease RRP4 N-terminal region S1 PF00575.18 EIE91768.1 - 0.029 14.4 1.6 1.7 8.7 0.2 2.5 3 0 0 3 3 3 0 S1 RNA binding domain CDC50 PF03381.10 EIE91771.1 - 1.2e-79 267.3 0.1 6.3e-79 265.0 0.1 1.9 2 0 0 2 2 2 1 LEM3 (ligand-effect modulator 3) family / CDC50 family ATG27 PF09451.5 EIE91771.1 - 1.5e-07 30.9 4.5 3.7e-07 29.6 3.2 1.6 1 1 0 1 1 1 1 Autophagy-related protein 27 Phage_head_chap PF11113.3 EIE91771.1 - 0.15 11.9 0.0 0.92 9.4 0.0 2.3 2 0 0 2 2 2 0 Head assembly gene product DUF2404 PF10296.4 EIE91772.1 - 4.1e-25 87.7 0.0 8.4e-25 86.7 0.0 1.5 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) PH PF00169.24 EIE91772.1 - 6.1e-05 23.1 0.3 0.00016 21.8 0.2 1.8 1 0 0 1 1 1 1 PH domain PEN-2 PF10251.4 EIE91772.1 - 0.14 12.3 1.4 9.2 6.5 0.1 2.5 2 0 0 2 2 2 0 Presenilin enhancer-2 subunit of gamma secretase HATPase_c PF02518.21 EIE91775.1 - 3e-29 100.9 0.1 6.4e-29 99.9 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EIE91775.1 - 3e-21 75.5 0.2 1e-19 70.5 0.0 2.5 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 EIE91775.1 - 3.3e-18 65.4 0.0 1e-17 63.8 0.0 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain AAA_16 PF13191.1 EIE91775.1 - 9.7e-18 64.8 0.0 2.4e-17 63.5 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain GAF_2 PF13185.1 EIE91775.1 - 1.9e-11 44.6 0.0 6.3e-11 42.9 0.0 1.9 1 0 0 1 1 1 1 GAF domain Pkinase PF00069.20 EIE91775.1 - 5.4e-10 38.8 0.0 1.2e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain GAF_3 PF13492.1 EIE91775.1 - 1.3e-08 34.9 0.0 4.7e-08 33.1 0.0 2.0 2 0 0 2 2 2 1 GAF domain GAF PF01590.21 EIE91775.1 - 6.9e-07 29.5 0.0 1.5e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 GAF domain NB-ARC PF00931.17 EIE91775.1 - 1.3e-05 24.2 0.0 3e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain AAA_29 PF13555.1 EIE91775.1 - 0.00035 20.0 0.1 0.0013 18.2 0.0 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain Pkinase_Tyr PF07714.12 EIE91775.1 - 0.00092 18.3 0.0 0.0018 17.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase ArsA_ATPase PF02374.10 EIE91775.1 - 0.0049 15.9 0.6 0.28 10.1 0.0 2.5 2 0 0 2 2 2 1 Anion-transporting ATPase AAA PF00004.24 EIE91775.1 - 0.006 16.7 0.0 0.031 14.4 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 EIE91775.1 - 0.0096 15.1 0.1 0.023 13.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EIE91775.1 - 0.015 15.4 0.0 0.072 13.2 0.0 2.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EIE91775.1 - 0.018 15.3 0.0 0.052 13.8 0.0 1.8 1 0 0 1 1 1 0 ABC transporter TPR_11 PF13414.1 EIE91775.1 - 0.13 11.9 0.0 0.13 11.9 0.0 3.7 4 0 0 4 4 4 0 TPR repeat AAA_30 PF13604.1 EIE91775.1 - 0.23 10.9 0.1 0.54 9.7 0.1 1.5 1 0 0 1 1 1 0 AAA domain DUF3921 PF13060.1 EIE91776.1 - 0.1 12.5 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3921) MFS_1 PF07690.11 EIE91777.1 - 2.3e-25 89.0 27.3 8.3e-19 67.5 5.8 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_C3 PF00548.15 EIE91783.1 - 0.058 13.2 0.0 0.061 13.1 0.0 1.0 1 0 0 1 1 1 0 3C cysteine protease (picornain 3C) AMO PF02461.11 EIE91784.1 - 0.024 14.3 2.1 0.045 13.4 1.5 1.4 1 0 0 1 1 1 0 Ammonia monooxygenase DDE_3 PF13358.1 EIE91785.1 - 0.03 14.0 0.1 0.034 13.9 0.1 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease AAA_30 PF13604.1 EIE91787.1 - 0.01 15.3 0.0 0.014 15.0 0.0 1.1 1 0 0 1 1 1 0 AAA domain Cation_ATPase_C PF00689.16 EIE91788.1 - 2.7 7.4 9.6 0.82 9.1 1.1 2.2 1 1 1 2 2 2 0 Cation transporting ATPase, C-terminus DDE_1 PF03184.14 EIE91790.1 - 1.2e-16 60.4 2.1 2.1e-13 49.9 0.3 2.8 2 1 1 3 3 3 2 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EIE91790.1 - 3.2e-06 26.8 0.0 6.2e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.1 EIE91790.1 - 0.041 13.6 0.0 0.097 12.4 0.0 1.6 1 0 0 1 1 1 0 DDE superfamily endonuclease FAR1 PF03101.10 EIE91791.1 - 0.00032 21.1 0.5 0.00061 20.2 0.4 1.4 1 0 0 1 1 1 1 FAR1 DNA-binding domain SspN PF08177.6 EIE91792.1 - 0.1 12.3 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Small acid-soluble spore protein N family Cation_ATPase_C PF00689.16 EIE91793.1 - 2.7 7.4 9.6 0.82 9.1 1.1 2.2 1 1 1 2 2 2 0 Cation transporting ATPase, C-terminus Ricin_B_lectin PF00652.17 EIE91794.1 - 3.3e-05 23.9 0.0 6.7e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 EIE91794.1 - 3.9e-05 23.9 0.4 0.03 14.7 0.0 1.8 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like PE PF00934.15 EIE91794.1 - 0.5 10.4 4.1 0.39 10.8 1.2 1.8 1 1 0 2 2 2 0 PE family BSD PF03909.12 EIE91795.1 - 4.9e-14 51.7 1.4 8e-14 51.1 0.1 2.0 2 0 0 2 2 2 1 BSD domain CodY PF06018.9 EIE91795.1 - 0.016 14.4 0.0 0.016 14.4 0.0 2.1 2 0 0 2 2 2 0 CodY GAF-like domain AAA_12 PF13087.1 EIE91795.1 - 0.4 10.0 5.2 6.7 6.0 0.5 2.6 1 1 1 2 2 2 0 AAA domain GOLD_2 PF13897.1 EIE91795.1 - 7.3 6.8 8.5 14 5.9 5.9 1.4 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking Glutaredoxin PF00462.19 EIE91796.1 - 7.8e-21 73.8 0.0 1.1e-20 73.3 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin Arteri_Gl PF00951.13 EIE91797.1 - 0.19 11.3 2.9 0.39 10.2 1.1 2.1 2 0 0 2 2 2 0 Arterivirus GL envelope glycoprotein Colipase-like PF15083.1 EIE91799.1 - 0.042 13.7 0.1 0.11 12.4 0.1 1.6 1 0 0 1 1 1 0 Colipase-like ENT PF03735.9 EIE91801.1 - 0.12 12.1 0.1 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 ENT domain VIT1 PF01988.14 EIE91801.1 - 7.7 5.9 7.9 2.5 7.5 1.7 2.5 3 0 0 3 3 3 0 VIT family zf-C2H2_4 PF13894.1 EIE91802.1 - 0.0018 18.4 12.3 0.0059 16.8 2.2 3.4 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2 PF00096.21 EIE91802.1 - 0.0061 16.8 1.9 0.0061 16.8 1.3 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EIE91802.1 - 0.022 14.6 1.4 0.022 14.6 0.9 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger DSBA PF01323.15 EIE91802.1 - 0.027 14.0 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 DSBA-like thioredoxin domain SerH PF06873.6 EIE91802.1 - 0.051 12.1 1.2 0.095 11.2 0.4 1.7 2 0 0 2 2 2 0 Cell surface immobilisation antigen SerH Zn-ribbon_8 PF09723.5 EIE91802.1 - 0.13 12.2 8.8 1.4 8.8 0.4 3.4 3 0 0 3 3 3 0 Zinc ribbon domain zf-C2H2_2 PF12756.2 EIE91802.1 - 0.17 12.0 3.4 0.17 12.0 1.3 1.8 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF2082 PF09855.4 EIE91802.1 - 0.27 11.0 3.5 1.1 9.2 0.2 2.7 3 0 0 3 3 3 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) Prok-RING_1 PF14446.1 EIE91802.1 - 0.56 9.9 3.2 4.4 7.1 0.1 3.0 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 Rpr2 PF04032.11 EIE91802.1 - 0.68 9.8 0.0 0.68 9.8 0.0 2.6 3 1 1 4 4 4 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-H2C2_5 PF13909.1 EIE91802.1 - 1.1 9.6 4.5 2 8.8 2.0 2.4 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-AD PF07776.10 EIE91802.1 - 1.4 8.9 5.7 6.9 6.7 1.0 2.8 2 1 1 3 3 3 0 Zinc-finger associated domain (zf-AD) DUF2296 PF10058.4 EIE91802.1 - 4 7.2 6.0 17 5.2 0.2 3.2 3 1 0 3 3 3 0 Predicted integral membrane metal-binding protein (DUF2296) DUF706 PF05153.10 EIE91805.1 - 1.5e-110 368.5 5.4 1.7e-110 368.2 3.7 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF706) HD PF01966.17 EIE91805.1 - 0.0048 16.8 0.6 0.18 11.7 0.1 2.9 2 1 0 2 2 2 1 HD domain Abi_2 PF07751.6 EIE91805.1 - 0.0076 16.4 0.6 0.015 15.5 0.4 1.5 1 0 0 1 1 1 1 Abi-like protein Methyltransf_32 PF13679.1 EIE91806.1 - 1.7e-27 95.8 0.2 2.2e-27 95.4 0.1 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIE91806.1 - 0.00029 21.3 0.1 0.00074 20.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIE91806.1 - 0.00045 19.8 0.0 0.00065 19.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIE91806.1 - 0.00049 19.8 0.0 0.00065 19.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EIE91806.1 - 0.0019 17.3 0.2 0.003 16.6 0.2 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 EIE91806.1 - 0.0037 16.6 0.0 0.0055 16.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.7 EIE91806.1 - 0.004 17.6 0.0 0.0076 16.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIE91806.1 - 0.012 16.0 0.0 0.024 15.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain TRM13 PF05206.9 EIE91806.1 - 0.059 12.5 0.2 0.077 12.2 0.1 1.2 1 0 0 1 1 1 0 Methyltransferase TRM13 Methyltransf_25 PF13649.1 EIE91806.1 - 0.11 12.8 0.1 0.24 11.7 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Ribosomal_L6 PF00347.18 EIE91807.1 - 3.4e-21 75.5 0.0 1.7e-15 57.2 0.0 2.3 2 1 0 2 2 2 2 Ribosomal protein L6 RNA_pol_Rpb1_5 PF04998.12 EIE91808.1 - 2.7e-96 322.0 0.0 3.4e-95 318.4 0.0 2.4 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EIE91808.1 - 2.1e-61 206.7 0.0 5.4e-61 205.3 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EIE91808.1 - 1.7e-35 122.0 0.0 6.3e-35 120.2 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.7 EIE91808.1 - 3.4e-26 92.3 0.4 3.4e-26 92.3 0.3 3.7 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.12 EIE91808.1 - 4.1e-24 84.4 0.1 1.5e-23 82.6 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 SNARE PF05739.14 EIE91809.1 - 8.7e-07 28.5 9.8 1.3e-05 24.8 0.7 2.9 3 0 0 3 3 3 2 SNARE domain V-SNARE_C PF12352.3 EIE91809.1 - 0.015 15.3 3.6 0.09 12.8 0.2 2.7 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Laminin_II PF06009.7 EIE91809.1 - 0.023 14.4 6.9 0.43 10.3 0.2 2.6 2 0 0 2 2 2 0 Laminin Domain II DASH_Hsk3 PF08227.6 EIE91809.1 - 0.33 11.1 2.0 3.2 8.0 0.2 2.8 2 1 0 2 2 2 0 DASH complex subunit Hsk3 like DUF4201 PF13870.1 EIE91809.1 - 0.52 9.7 13.1 0.78 9.1 4.7 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4201) HrpA_pilin PF09589.5 EIE91809.1 - 1.5 9.2 7.0 0.28 11.6 2.1 1.9 2 0 0 2 2 2 0 HrpA pilus formation protein NPV_P10 PF05531.7 EIE91809.1 - 3.7 7.8 10.8 6.9 6.9 2.8 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF948 PF06103.6 EIE91809.1 - 6.5 6.6 6.7 9.9 6.0 0.8 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) CENP-F_leu_zip PF10473.4 EIE91810.1 - 0.0055 16.5 0.5 0.0055 16.5 0.3 2.8 2 1 1 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Mg_trans_NIPA PF05653.9 EIE91811.1 - 1.2e-63 214.8 13.4 2.9e-60 203.7 8.9 2.0 2 0 0 2 2 2 2 Magnesium transporter NIPA EmrE PF13536.1 EIE91811.1 - 1.1e-06 28.8 0.3 1.1e-06 28.8 0.2 3.5 3 1 1 4 4 4 2 Multidrug resistance efflux transporter EamA PF00892.15 EIE91811.1 - 7.7e-06 25.9 0.7 7.7e-06 25.9 0.5 4.3 3 1 0 3 3 3 1 EamA-like transporter family Git3_C PF11970.3 EIE91811.1 - 0.061 13.1 1.3 0.17 11.6 0.9 1.8 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 C-term Mito_carr PF00153.22 EIE91812.1 - 1.3e-21 76.0 0.0 1.8e-15 56.4 0.0 2.5 2 0 0 2 2 2 2 Mitochondrial carrier protein WD40 PF00400.27 EIE91812.1 - 6.9e-18 63.7 0.2 1.5e-06 27.8 0.1 4.6 5 0 0 5 5 5 3 WD domain, G-beta repeat PSII_BNR PF14870.1 EIE91812.1 - 0.0012 17.9 0.0 0.23 10.4 0.0 2.4 2 0 0 2 2 2 2 Photosynthesis system II assembly factor YCF48 GSDH PF07995.6 EIE91812.1 - 0.0062 15.6 0.0 2 7.4 0.0 3.0 3 1 0 3 3 3 2 Glucose / Sorbosone dehydrogenase CPSF_A PF03178.10 EIE91812.1 - 0.014 14.5 0.2 0.37 9.8 0.1 2.7 1 1 0 1 1 1 0 CPSF A subunit region Abhydrolase_3 PF07859.8 EIE91813.1 - 3.9e-49 167.0 0.0 4.8e-49 166.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EIE91813.1 - 1.5e-16 60.0 0.0 8e-16 57.6 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) COesterase PF00135.23 EIE91813.1 - 6.3e-06 25.1 0.1 2e-05 23.4 0.1 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 EIE91813.1 - 6.8e-06 25.8 0.0 9.2e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EIE91813.1 - 0.0028 16.8 0.0 0.0072 15.5 0.0 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 EIE91813.1 - 0.0033 16.9 0.0 0.058 12.8 0.0 2.6 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase MgtE PF01769.11 EIE91814.1 - 0.26 11.5 6.2 0.047 13.9 1.6 1.7 2 0 0 2 2 2 0 Divalent cation transporter Sec66 PF09802.4 EIE91815.1 - 3.3e-21 75.5 9.9 3.3e-21 75.5 6.8 1.5 1 1 0 1 1 1 1 Preprotein translocase subunit Sec66 Dsl1_C PF11989.3 EIE91815.1 - 0.11 11.6 5.4 0.12 11.5 3.8 1.1 1 0 0 1 1 1 0 Retrograde transport protein Dsl1 C terminal Adeno_VII PF03228.9 EIE91815.1 - 0.68 10.5 3.5 1 9.9 2.4 1.3 1 0 0 1 1 1 0 Adenoviral core protein VII DUF2500 PF10694.4 EIE91815.1 - 0.75 9.8 4.9 0.36 10.8 2.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2500) Pilt PF15453.1 EIE91815.1 - 2.5 7.6 13.5 2.7 7.5 9.4 1.0 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions S10_plectin PF03501.10 EIE91817.1 - 1.7e-42 143.2 0.1 2e-42 142.9 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain DUF2250 PF10007.4 EIE91817.1 - 0.03 14.2 1.1 5.1 7.0 0.0 2.3 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) TrmB PF01978.14 EIE91817.1 - 0.033 13.8 0.0 0.08 12.6 0.0 1.6 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_45 PF14947.1 EIE91817.1 - 0.061 13.1 0.1 0.092 12.5 0.1 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix Methyltransf_16 PF10294.4 EIE91818.1 - 2.9e-09 36.6 0.0 0.00043 19.7 0.0 2.2 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_31 PF13847.1 EIE91818.1 - 9.4e-05 22.0 0.0 0.084 12.4 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.1 EIE91818.1 - 0.00022 21.0 0.0 0.00038 20.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIE91818.1 - 0.00065 20.2 0.0 0.0029 18.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIE91818.1 - 0.0022 18.4 0.0 1.5 9.3 0.0 3.0 3 0 0 3 3 3 1 Methyltransferase domain MTS PF05175.9 EIE91818.1 - 0.0082 15.5 0.0 0.02 14.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain TehB PF03848.9 EIE91818.1 - 0.056 12.6 0.0 0.14 11.3 0.0 1.6 1 0 0 1 1 1 0 Tellurite resistance protein TehB DNA_pol_phi PF04931.8 EIE91818.1 - 0.65 7.6 10.5 1.1 6.9 7.2 1.3 1 0 0 1 1 1 0 DNA polymerase phi Pox_Ag35 PF03286.9 EIE91818.1 - 2.2 7.7 9.9 0.052 13.0 2.0 1.8 2 0 0 2 2 2 0 Pox virus Ag35 surface protein CENP-B_dimeris PF09026.5 EIE91818.1 - 4.5 7.5 15.5 19 5.5 7.9 3.3 3 0 0 3 3 3 0 Centromere protein B dimerisation domain ALO PF04030.9 EIE91819.1 - 1e-77 261.2 1.6 1e-77 261.2 1.1 1.9 3 0 0 3 3 3 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 EIE91819.1 - 7.9e-27 93.4 0.0 1.3e-26 92.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain bZIP_2 PF07716.10 EIE91819.1 - 9.8e-12 44.5 13.4 3e-11 42.9 9.3 1.9 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 EIE91819.1 - 1.1e-06 28.4 9.7 1.1e-06 28.4 6.7 2.4 2 0 0 2 2 2 1 bZIP transcription factor DUF2203 PF09969.4 EIE91819.1 - 0.06 13.5 1.5 5.2 7.3 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Spt5_N PF11942.3 EIE91819.1 - 0.29 11.7 6.9 0.61 10.7 4.8 1.5 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal IncA PF04156.9 EIE91819.1 - 0.41 10.2 2.4 1.1 8.8 1.7 1.6 1 0 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 EIE91819.1 - 1.3 6.7 3.9 2 6.1 2.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1775 PF07987.6 EIE91820.1 - 3.3e-25 88.6 0.1 4.3e-25 88.2 0.1 1.1 1 0 0 1 1 1 1 Domain of unkown function (DUF1775) EF-hand_1 PF00036.27 EIE91821.1 - 2.6e-24 82.6 17.7 1.1e-07 30.5 0.9 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EIE91821.1 - 2.9e-22 78.5 5.3 5.3e-12 45.7 1.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EIE91821.1 - 5e-18 63.3 12.1 3.5e-05 23.3 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EIE91821.1 - 5.7e-17 60.2 19.3 6.7e-06 25.2 0.4 4.7 4 1 1 5 5 5 4 EF hand EF-hand_8 PF13833.1 EIE91821.1 - 9.2e-12 44.3 18.5 0.00017 21.1 1.7 4.7 2 2 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EIE91821.1 - 1.5e-05 24.9 0.0 0.0064 16.5 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EIE91821.1 - 0.00091 18.9 9.1 0.021 14.5 0.5 3.7 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 EIE91821.1 - 0.018 14.9 0.1 0.23 11.3 0.0 2.6 2 1 1 3 3 3 0 EF-hand domain Mqo PF06039.10 EIE91821.1 - 0.05 11.7 0.0 0.058 11.5 0.0 1.2 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) AICARFT_IMPCHas PF01808.13 EIE91822.1 - 9e-118 392.9 0.7 1.4e-117 392.3 0.5 1.3 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 EIE91822.1 - 3.9e-25 87.5 0.1 1.5e-24 85.7 0.0 2.1 2 0 0 2 2 2 1 MGS-like domain DDE_3 PF13358.1 EIE91825.1 - 7e-13 48.5 0.2 9e-13 48.2 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_7 PF02796.10 EIE91827.1 - 0.025 14.4 0.3 0.059 13.2 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase GcrA PF07750.6 EIE91827.1 - 0.087 13.0 0.1 0.12 12.5 0.1 1.3 1 0 0 1 1 1 0 GcrA cell cycle regulator rve PF00665.21 EIE91828.1 - 2.4e-24 85.7 0.0 7.5e-24 84.1 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE91828.1 - 6.9e-17 61.5 0.0 1.4e-16 60.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE91828.1 - 9.2e-11 41.2 0.6 2.6e-10 39.8 0.4 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.1 EIE91828.1 - 0.0003 21.2 0.2 0.00084 19.7 0.2 1.8 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.5 EIE91828.1 - 0.0004 19.7 0.1 0.0011 18.3 0.1 1.8 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger UBN2_2 PF14227.1 EIE91828.1 - 0.0041 16.6 1.3 0.067 12.7 0.0 2.8 3 0 0 3 3 3 1 gag-polypeptide of LTR copia-type rve_3 PF13683.1 EIE91828.1 - 0.017 14.6 0.0 0.052 13.0 0.0 1.9 1 0 0 1 1 1 0 Integrase core domain UBN2 PF14223.1 EIE91828.1 - 0.032 14.0 0.4 0.091 12.5 0.0 1.9 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type Asp_protease PF09668.5 EIE91828.1 - 0.082 12.4 0.1 0.23 11.0 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.1 EIE91828.1 - 0.14 11.9 0.0 0.31 10.8 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DDE_3 PF13358.1 EIE91829.1 - 7.1e-19 67.9 0.0 9.6e-19 67.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE91829.1 - 0.017 15.2 0.0 0.034 14.2 0.0 1.6 1 1 0 1 1 1 0 Integrase core domain Myb_DNA-bind_5 PF13873.1 EIE91829.1 - 0.057 13.3 0.7 5.2 7.0 0.2 2.5 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain DUF1033 PF06279.6 EIE91829.1 - 0.067 13.0 0.3 0.11 12.2 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1033) DDE_3 PF13358.1 EIE91830.1 - 4.3e-21 75.2 0.4 5.9e-21 74.7 0.3 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Phage_integrase PF00589.17 EIE91831.1 - 6.1e-11 42.2 1.9 9.4e-10 38.4 0.5 2.2 2 0 0 2 2 2 1 Phage integrase family Phage_int_SAM_1 PF02899.12 EIE91831.1 - 0.00035 20.6 1.6 0.002 18.2 0.2 2.6 2 1 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Integrase_1 PF12835.2 EIE91831.1 - 0.068 12.9 0.1 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 Integrase HTH_Tnp_Tc3_2 PF01498.13 EIE91832.1 - 2.6e-08 33.7 0.3 6e-08 32.6 0.1 1.8 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.1 EIE91832.1 - 3.7e-06 26.7 0.6 0.00036 20.3 0.4 2.3 1 1 1 2 2 2 2 DDE superfamily endonuclease Dicty_REP PF05086.7 EIE91833.1 - 4.8 4.8 12.8 7.3 4.1 8.9 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DDE_3 PF13358.1 EIE91834.1 - 4.7e-20 71.8 0.1 8.8e-20 70.9 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE91834.1 - 1.9e-19 69.5 2.2 4.5e-19 68.2 0.7 2.2 3 0 0 3 3 3 1 Transposase HTH_29 PF13551.1 EIE91834.1 - 3.6e-08 33.5 0.9 1.1e-07 31.9 0.7 1.8 1 0 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.1 EIE91834.1 - 0.0014 19.3 0.2 0.0014 19.3 0.1 3.9 5 1 1 6 6 5 1 Homeodomain-like domain HTH_23 PF13384.1 EIE91834.1 - 0.002 17.6 1.0 0.019 14.5 0.0 2.9 3 0 0 3 3 3 1 Homeodomain-like domain Ku_PK_bind PF08785.6 EIE91834.1 - 0.0057 16.5 0.1 0.015 15.1 0.0 1.8 2 0 0 2 2 2 1 Ku C terminal domain like rve PF00665.21 EIE91834.1 - 0.0087 16.1 0.0 0.03 14.4 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain HTH_28 PF13518.1 EIE91834.1 - 0.016 15.1 0.0 0.069 13.1 0.0 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_21 PF13276.1 EIE91834.1 - 0.024 14.6 0.0 0.28 11.2 0.0 2.6 2 0 0 2 2 2 0 HTH-like domain Trp_repressor PF01371.14 EIE91834.1 - 0.13 12.2 0.0 0.98 9.3 0.0 2.2 2 0 0 2 2 2 0 Trp repressor protein HTH_40 PF14493.1 EIE91834.1 - 0.16 12.2 0.3 2.9 8.1 0.0 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.13 EIE91835.1 - 2.9e-08 33.6 0.3 6e-08 32.6 0.1 1.7 2 0 0 2 2 2 1 Transposase Endonuclease_5 PF04493.9 EIE91835.1 - 0.14 11.5 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Endonuclease V HTH_Tnp_Tc3_2 PF01498.13 EIE91837.1 - 2.8e-10 40.0 0.3 7.4e-10 38.7 0.2 1.8 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.1 EIE91837.1 - 6.4e-09 35.7 1.1 1.8e-08 34.2 0.2 2.0 2 1 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE91839.1 - 2.6e-13 49.8 0.5 5.5e-13 48.7 0.3 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.1 EIE91839.1 - 0.0011 18.7 0.0 0.0021 17.7 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 EIE91839.1 - 0.037 14.1 0.1 0.076 13.1 0.1 1.6 1 0 0 1 1 1 0 Winged helix-turn helix HTH_32 PF13565.1 EIE91839.1 - 0.63 10.8 3.3 1.8 9.3 0.1 2.9 2 2 0 2 2 2 0 Homeodomain-like domain DDE_3 PF13358.1 EIE91840.1 - 1.4e-21 76.7 0.3 2.8e-21 75.8 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE91840.1 - 1.3e-15 57.1 1.4 6.7e-15 54.9 0.2 2.5 3 0 0 3 3 3 1 Transposase HTH_29 PF13551.1 EIE91840.1 - 1.7e-05 24.9 0.2 7e-05 22.9 0.1 2.0 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.1 EIE91840.1 - 0.00023 21.9 3.5 0.013 16.2 0.1 3.8 3 1 1 4 4 4 1 Homeodomain-like domain HTH_38 PF13936.1 EIE91840.1 - 0.0007 19.0 0.0 0.0016 17.9 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_21 PF13276.1 EIE91840.1 - 0.0012 18.7 0.1 0.1 12.6 0.0 2.8 3 0 0 3 3 3 1 HTH-like domain rve PF00665.21 EIE91840.1 - 0.002 18.2 0.0 0.0054 16.8 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain HTH_23 PF13384.1 EIE91840.1 - 0.0032 17.0 0.3 0.062 12.9 0.0 2.8 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.1 EIE91840.1 - 0.011 15.7 0.0 0.058 13.4 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_7 PF02796.10 EIE91840.1 - 0.032 14.0 1.7 0.85 9.5 0.1 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain of resolvase SET PF00856.23 EIE91842.1 - 2.4e-28 99.4 2.7 2.2e-27 96.3 0.5 2.8 2 1 0 2 2 2 1 SET domain Pre-SET PF05033.11 EIE91842.1 - 1.9e-17 63.3 5.1 1.9e-17 63.3 3.5 2.6 2 0 0 2 2 2 1 Pre-SET motif Chromo PF00385.19 EIE91842.1 - 3.3e-07 29.8 0.4 6.8e-07 28.8 0.3 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DDE_3 PF13358.1 EIE91843.1 - 8.4e-21 74.2 0.1 1.5e-20 73.4 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE91843.1 - 1.6e-16 60.1 2.2 3.2e-16 59.1 0.1 2.5 3 0 0 3 3 2 1 Transposase HTH_29 PF13551.1 EIE91843.1 - 1.1e-08 35.2 0.2 3.6e-08 33.5 0.2 1.9 2 0 0 2 2 1 1 Winged helix-turn helix HTH_23 PF13384.1 EIE91843.1 - 7.9e-06 25.3 0.1 7e-05 22.3 0.0 2.6 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.1 EIE91843.1 - 0.00024 21.0 0.0 0.0015 18.5 0.0 2.5 3 0 0 3 3 2 1 Helix-turn-helix domain rve PF00665.21 EIE91843.1 - 0.0046 17.0 0.0 0.015 15.3 0.0 1.9 2 1 1 3 3 3 1 Integrase core domain HTH_17 PF12728.2 EIE91843.1 - 0.0081 16.3 0.2 0.64 10.3 0.0 3.2 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_40 PF14493.1 EIE91843.1 - 0.011 15.9 0.2 0.59 10.3 0.0 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain ATC_hydrolase PF14196.1 EIE91843.1 - 0.012 15.9 0.0 6.1 7.2 0.0 2.9 3 0 0 3 3 3 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase HTH_7 PF02796.10 EIE91843.1 - 0.019 14.8 0.6 0.045 13.6 0.1 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_21 PF13276.1 EIE91843.1 - 0.02 14.9 0.0 0.18 11.8 0.0 2.6 2 0 0 2 2 2 0 HTH-like domain FUR PF01475.14 EIE91843.1 - 0.02 14.8 0.1 3 7.7 0.0 3.0 3 0 0 3 3 3 0 Ferric uptake regulator family Ku_PK_bind PF08785.6 EIE91843.1 - 0.025 14.4 0.0 0.066 13.1 0.0 1.8 1 0 0 1 1 1 0 Ku C terminal domain like HTH_IclR PF09339.5 EIE91843.1 - 0.08 12.5 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain Trp_repressor PF01371.14 EIE91843.1 - 0.12 12.2 0.0 0.34 10.8 0.0 1.7 1 0 0 1 1 1 0 Trp repressor protein HTH_32 PF13565.1 EIE91843.1 - 0.23 12.2 3.3 0.77 10.5 0.0 3.5 5 1 1 6 6 5 0 Homeodomain-like domain DDE_3 PF13358.1 EIE91844.1 - 1.4e-21 76.7 0.3 2.8e-21 75.8 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE91844.1 - 1.3e-15 57.1 1.4 6.7e-15 54.9 0.2 2.5 3 0 0 3 3 3 1 Transposase HTH_29 PF13551.1 EIE91844.1 - 1.7e-05 24.9 0.2 7e-05 22.9 0.1 2.0 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.1 EIE91844.1 - 0.00023 21.9 3.5 0.013 16.2 0.1 3.8 3 1 1 4 4 4 1 Homeodomain-like domain HTH_38 PF13936.1 EIE91844.1 - 0.0007 19.0 0.0 0.0016 17.9 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_21 PF13276.1 EIE91844.1 - 0.0012 18.7 0.1 0.1 12.6 0.0 2.8 3 0 0 3 3 3 1 HTH-like domain rve PF00665.21 EIE91844.1 - 0.002 18.2 0.0 0.0054 16.8 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain HTH_23 PF13384.1 EIE91844.1 - 0.0032 17.0 0.3 0.062 12.9 0.0 2.8 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.1 EIE91844.1 - 0.011 15.7 0.0 0.058 13.4 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_7 PF02796.10 EIE91844.1 - 0.032 14.0 1.7 0.85 9.5 0.1 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain of resolvase DUF1759 PF03564.10 EIE91845.1 - 7e-05 22.6 0.2 0.00011 22.0 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) Retrotrans_gag PF03732.12 EIE91845.1 - 0.0021 18.1 0.0 0.0045 17.0 0.0 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein rve PF00665.21 EIE91846.1 - 2.3e-23 82.5 0.0 2.5e-22 79.2 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 EIE91846.1 - 2.3e-16 59.8 0.0 4.6e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE91846.1 - 2.7e-11 42.9 0.2 6.5e-11 41.7 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.1 EIE91846.1 - 5.1e-06 26.9 0.0 2.2e-05 24.8 0.0 2.2 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.12 EIE91846.1 - 8.6e-06 25.7 1.0 2.1e-05 24.4 0.0 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein UBN2_2 PF14227.1 EIE91846.1 - 5.6e-05 22.6 0.9 0.0011 18.5 0.1 3.4 4 1 0 4 4 4 1 gag-polypeptide of LTR copia-type gag-asp_proteas PF13975.1 EIE91846.1 - 0.00024 20.8 0.0 0.00049 19.8 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease UBN2 PF14223.1 EIE91846.1 - 0.00069 19.3 0.8 0.26 11.0 0.1 2.9 3 0 0 3 3 3 2 gag-polypeptide of LTR copia-type zf-H2C2 PF09337.5 EIE91846.1 - 0.0089 15.4 0.1 0.029 13.7 0.0 2.0 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger DUF1759 PF03564.10 EIE91847.1 - 0.00018 21.3 0.3 0.00027 20.7 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) Retrotrans_gag PF03732.12 EIE91847.1 - 0.00098 19.1 0.3 0.0026 17.7 0.0 1.8 2 0 0 2 2 2 1 Retrotransposon gag protein Asp_protease_2 PF13650.1 EIE91849.1 - 1.4e-06 28.6 0.0 2.8e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EIE91849.1 - 0.00023 20.9 0.0 0.00045 19.9 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 EIE91849.1 - 0.077 12.9 0.1 0.21 11.4 0.1 1.8 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.5 EIE91849.1 - 0.17 11.4 0.0 0.34 10.4 0.0 1.5 1 1 0 1 1 1 0 Aspartyl protease rve PF00665.21 EIE91850.1 - 3.8e-24 85.1 0.0 9.9e-23 80.5 0.0 2.6 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 EIE91850.1 - 3.9e-15 55.7 0.1 7.1e-15 54.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE91850.1 - 1.4e-10 40.6 0.2 2.9e-10 39.6 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 EIE91850.1 - 0.0061 15.9 0.1 0.014 14.8 0.0 1.7 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger rve PF00665.21 EIE91851.1 - 3.2e-23 82.1 0.0 5.4e-23 81.3 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 EIE91851.1 - 9.4e-09 34.8 0.1 1.7e-08 34.0 0.1 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 EIE91851.1 - 0.016 14.9 0.2 0.063 13.0 0.2 2.0 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain DUF2209 PF09974.4 EIE91852.1 - 0.036 14.1 0.0 0.12 12.4 0.0 1.8 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2209) zf-CCHC PF00098.18 EIE91855.1 - 4.9e-05 23.0 11.2 0.0039 17.0 0.9 2.3 2 0 0 2 2 2 2 Zinc knuckle RRM_1 PF00076.17 EIE91855.1 - 0.057 13.0 0.0 0.17 11.5 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC_4 PF14392.1 EIE91855.1 - 0.084 12.5 6.4 0.12 12.0 0.4 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_3 PF13917.1 EIE91855.1 - 3.6 7.3 8.7 2.6 7.8 0.1 2.5 1 1 1 2 2 2 0 Zinc knuckle Zn_ribbon_2 PF12674.2 EIE91855.1 - 6.3 7.2 7.7 23 5.4 1.5 2.6 1 1 1 2 2 2 0 Putative zinc ribbon domain DUF4436 PF14494.1 EIE91856.1 - 5.3e-15 55.4 6.6 9.8e-10 38.1 4.3 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF4436) DUF4052 PF13261.1 EIE91856.1 - 0.013 14.9 3.7 0.022 14.1 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4052) ABC2_membrane_4 PF12730.2 EIE91856.1 - 0.037 13.1 9.8 0.041 13.0 6.1 1.6 1 1 0 1 1 1 0 ABC-2 family transporter protein Cyt-b5 PF00173.23 EIE91857.1 - 1.3e-21 76.2 0.0 1.8e-21 75.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain HIG_1_N PF04588.8 EIE91858.1 - 2.2e-06 27.3 2.1 2.2e-06 27.3 1.5 2.0 2 0 0 2 2 2 1 Hypoxia induced protein conserved region HR1 PF02185.11 EIE91859.1 - 0.00068 19.3 1.6 0.0018 18.0 0.4 2.0 2 0 0 2 2 2 1 Hr1 repeat Ima1_N PF09779.4 EIE91859.1 - 0.02 15.3 0.1 0.054 13.9 0.0 1.8 1 0 0 1 1 1 0 Ima1 N-terminal domain IncA PF04156.9 EIE91859.1 - 0.058 12.9 0.1 0.079 12.5 0.0 1.3 1 0 0 1 1 1 0 IncA protein TMF_TATA_bd PF12325.3 EIE91859.1 - 0.059 13.1 0.4 0.4 10.4 0.1 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding zinc_ribbon_5 PF13719.1 EIE91859.1 - 0.061 12.9 0.8 8.8 6.0 0.1 3.1 3 0 0 3 3 3 0 zinc-ribbon domain SlyX PF04102.7 EIE91859.1 - 0.062 13.6 2.0 0.18 12.2 1.4 1.7 1 0 0 1 1 1 0 SlyX Surfac_D-trimer PF09006.6 EIE91859.1 - 0.07 12.8 0.9 0.37 10.5 0.5 2.2 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation Filament PF00038.16 EIE91859.1 - 0.08 12.3 2.1 0.061 12.7 0.5 1.5 2 0 0 2 2 2 0 Intermediate filament protein zinc_ribbon_4 PF13717.1 EIE91859.1 - 0.082 12.6 0.7 10 5.9 0.1 3.1 3 0 0 3 3 3 0 zinc-ribbon domain T2SM PF04612.7 EIE91859.1 - 0.11 12.3 2.1 0.17 11.6 1.5 1.3 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M PyrI_C PF02748.10 EIE91859.1 - 0.11 11.9 0.2 7.6 6.0 0.0 2.4 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain DivIC PF04977.10 EIE91859.1 - 0.12 11.8 0.4 0.32 10.5 0.3 1.6 1 0 0 1 1 1 0 Septum formation initiator zf-C2H2 PF00096.21 EIE91859.1 - 0.16 12.4 3.2 1.3 9.4 0.2 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type Hrs_helical PF12210.3 EIE91859.1 - 0.16 12.2 0.9 0.74 10.1 0.3 2.3 2 0 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate FlaC_arch PF05377.6 EIE91859.1 - 0.72 9.7 2.6 1.6 8.6 0.0 2.5 3 0 0 3 3 2 0 Flagella accessory protein C (FlaC) DUF4349 PF14257.1 EIE91859.1 - 0.96 8.6 3.8 0.43 9.7 0.9 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) TMV_coat PF00721.16 EIE91860.1 - 0.0005 20.0 0.2 0.0012 18.7 0.1 1.6 1 0 0 1 1 1 1 Virus coat protein (TMV like) EntA_Immun PF08951.5 EIE91860.1 - 0.16 12.1 2.9 0.48 10.6 0.1 2.7 3 0 0 3 3 3 0 Enterocin A Immunity Acyltransferase PF01553.16 EIE91861.1 - 7.1e-12 44.8 0.0 6.5e-11 41.7 0.0 2.1 1 1 0 1 1 1 1 Acyltransferase WD40 PF00400.27 EIE91863.1 - 1.2e-47 158.1 5.0 1.9e-09 37.0 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Prp19 PF08606.6 EIE91863.1 - 1.2e-33 114.5 2.2 2.8e-33 113.4 1.5 1.6 1 0 0 1 1 1 1 Prp19/Pso4-like eIF2A PF08662.6 EIE91863.1 - 0.00033 20.4 0.9 0.032 13.9 0.1 3.3 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A U-box PF04564.10 EIE91863.1 - 0.00045 20.1 0.0 0.00095 19.0 0.0 1.5 1 0 0 1 1 1 1 U-box domain Nucleoporin_N PF08801.6 EIE91863.1 - 0.0022 16.8 0.2 0.12 11.1 0.0 2.9 2 1 0 3 3 3 1 Nup133 N terminal like WEMBL PF05701.6 EIE91863.1 - 0.0057 15.1 0.6 0.0082 14.6 0.4 1.2 1 0 0 1 1 1 1 Weak chloroplast movement under blue light DUF3450 PF11932.3 EIE91863.1 - 0.015 14.5 3.0 0.026 13.7 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF1631 PF07793.6 EIE91863.1 - 0.015 13.4 2.5 0.023 12.8 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) zf-Nse PF11789.3 EIE91863.1 - 0.042 13.3 0.0 0.081 12.4 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF4073 PF13285.1 EIE91863.1 - 0.047 13.1 0.1 3.7 6.9 0.0 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4073) Nbas_N PF15492.1 EIE91863.1 - 0.064 12.3 0.0 0.84 8.6 0.0 2.3 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal NUDIX PF00293.23 EIE91864.1 - 2.8e-10 39.9 0.4 4.2e-10 39.3 0.3 1.2 1 0 0 1 1 1 1 NUDIX domain zf-C2H2_2 PF12756.2 EIE91866.1 - 0.0026 17.8 2.9 0.55 10.3 0.1 2.0 1 1 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 EIE91866.1 - 0.14 12.5 6.2 0.29 11.5 0.5 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EIE91866.1 - 0.2 12.0 8.2 1.4 9.4 0.8 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EIE91866.1 - 0.48 10.6 2.9 6.2 7.0 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DUF629 PF04780.7 EIE91866.1 - 1.9 6.8 4.4 2 6.8 0.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF629) ER_lumen_recept PF00810.13 EIE91867.1 - 1.5e-38 132.5 4.4 2.2e-38 132.0 3.1 1.2 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 EIE91867.1 - 0.13 11.8 0.3 0.13 11.8 0.2 2.1 3 0 0 3 3 3 0 PQ loop repeat cNMP_binding PF00027.24 EIE91868.1 - 2e-27 94.8 0.0 3.3e-17 62.0 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.12 EIE91868.1 - 1e-07 31.2 0.2 2e-07 30.3 0.1 1.5 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit MIP-T3 PF10243.4 EIE91869.1 - 9.1 4.6 18.8 11 4.3 13.0 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Aldedh PF00171.17 EIE91870.1 - 1.7e-103 346.4 0.0 1.9e-103 346.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EIE91870.1 - 0.00093 18.4 0.0 0.0025 17.0 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1487) bZIP_1 PF00170.16 EIE91871.1 - 1.7e-08 34.2 18.9 9.7e-08 31.8 8.8 2.6 1 1 1 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.10 EIE91871.1 - 2e-06 27.4 11.6 2e-06 27.4 8.0 3.4 3 0 0 3 3 2 1 Basic region leucine zipper DUF972 PF06156.8 EIE91871.1 - 0.0013 19.0 7.7 0.0013 19.0 5.4 2.8 3 1 1 4 4 4 1 Protein of unknown function (DUF972) GAS PF13851.1 EIE91871.1 - 0.0032 16.6 10.4 0.0032 16.6 7.2 2.5 2 2 1 3 3 3 1 Growth-arrest specific micro-tubule binding DUF2205 PF10224.4 EIE91871.1 - 0.016 14.7 6.6 0.046 13.3 4.6 1.9 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) DUF2960 PF11173.3 EIE91871.1 - 0.026 14.8 0.1 0.096 13.0 0.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2960) TSC22 PF01166.13 EIE91871.1 - 0.071 13.0 6.5 0.41 10.6 4.5 2.5 1 0 0 1 1 1 0 TSC-22/dip/bun family bZIP_Maf PF03131.12 EIE91871.1 - 0.23 11.7 23.0 0.081 13.2 9.9 3.3 1 1 2 3 3 3 0 bZIP Maf transcription factor V_ATPase_I PF01496.14 EIE91871.1 - 0.5 8.1 12.2 0.11 10.3 6.1 1.6 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family APG6 PF04111.7 EIE91871.1 - 0.62 9.0 17.8 0.17 10.9 9.7 1.9 1 1 0 1 1 1 0 Autophagy protein Apg6 Macoilin PF09726.4 EIE91871.1 - 0.78 7.9 16.9 1.7 6.8 11.7 1.4 1 1 0 1 1 1 0 Transmembrane protein Phlebovirus_NSM PF07246.6 EIE91871.1 - 1.7 7.7 11.4 3.4 6.7 7.9 1.4 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M OPT PF03169.10 EIE91872.1 - 8.4e-190 632.3 47.5 9.5e-190 632.1 32.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Acetyltransf_7 PF13508.1 EIE91873.1 - 9.3e-08 32.1 0.0 2.2e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EIE91873.1 - 1.5e-07 31.3 0.0 2.8e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EIE91873.1 - 2.5e-06 27.6 0.0 5.4e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain RasGEF PF00617.14 EIE91874.1 - 2.6e-62 209.9 1.6 4.2e-62 209.2 0.2 2.1 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 EIE91874.1 - 1.1e-24 86.4 0.2 3.1e-24 85.0 0.2 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif WHIM2 PF15613.1 EIE91875.1 - 0.0073 16.2 0.0 0.037 13.9 0.0 2.0 2 0 0 2 2 2 1 WSTF, HB1, Itc1p, MBD9 motif 2 Peptidase_C50 PF03568.12 EIE91875.1 - 0.025 13.2 1.0 0.039 12.6 0.5 1.4 2 0 0 2 2 2 0 Peptidase family C50 Pmp3 PF01679.12 EIE91876.1 - 4.4e-24 83.9 5.1 4.9e-24 83.7 3.5 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DUF818 PF05677.7 EIE91876.1 - 0.21 10.2 1.4 0.2 10.3 1.0 1.0 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) RRM_1 PF00076.17 EIE91877.1 - 9.5e-20 70.0 0.2 1.2e-19 69.6 0.1 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE91877.1 - 3.7e-14 52.4 0.0 5e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE91877.1 - 7.6e-09 35.2 0.0 1.1e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ADH_N PF08240.7 EIE91878.1 - 2.4e-29 101.2 3.5 2.9e-29 100.9 1.3 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EIE91878.1 - 0.0046 17.8 0.2 0.046 14.6 0.1 2.2 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EIE91878.1 - 0.03 13.8 4.6 1.9 8.0 3.2 2.4 1 1 0 1 1 1 0 Zinc-binding dehydrogenase ThiF PF00899.16 EIE91879.1 - 4.7e-27 94.4 0.0 8.9e-27 93.5 0.0 1.5 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 EIE91879.1 - 0.0061 16.6 0.0 0.093 12.8 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase zf-H2C2_2 PF13465.1 EIE91880.1 - 7.6e-11 41.7 23.4 1.1e-06 28.6 2.7 3.6 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.21 EIE91880.1 - 1.7e-10 40.5 13.4 4.1e-05 23.6 2.6 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIE91880.1 - 7.5e-08 32.1 11.4 0.001 19.2 0.9 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger RPAP2_Rtr1 PF04181.8 EIE91880.1 - 0.019 15.0 0.5 0.04 14.0 0.1 1.6 1 1 1 2 2 2 0 Rtr1/RPAP2 family zf-C2H2_jaz PF12171.3 EIE91880.1 - 0.12 12.5 1.6 4.3 7.5 0.2 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 EIE91880.1 - 0.22 11.6 3.2 0.39 10.8 2.2 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Cut8_C PF08559.5 EIE91881.1 - 5.2e-09 36.0 0.3 7e-09 35.6 0.2 1.2 1 0 0 1 1 1 1 Cut8 six-helix bundle cwf21 PF08312.7 EIE91882.1 - 3.6e-17 61.9 9.0 4.5e-17 61.6 6.2 1.1 1 0 0 1 1 1 1 cwf21 domain CTNNBL PF08216.6 EIE91883.1 - 2.1e-30 104.4 0.2 2.1e-30 104.4 0.1 4.3 6 0 0 6 6 6 1 Catenin-beta-like, Arm-motif containing nuclear HEAT_2 PF13646.1 EIE91883.1 - 0.0011 19.1 0.7 1.7 8.9 0.0 4.0 2 2 0 3 3 3 2 HEAT repeats p450 PF00067.17 EIE91884.1 - 1.5e-72 244.6 0.0 1.9e-72 244.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SWIB PF02201.13 EIE91885.1 - 8.5e-26 89.4 0.0 1.2e-25 88.9 0.0 1.2 1 0 0 1 1 1 1 SWIB/MDM2 domain Recep_L_domain PF01030.19 EIE91886.1 - 2.8e-08 33.7 0.1 0.078 12.9 0.0 4.6 2 1 2 4 4 4 2 Receptor L domain LRR_5 PF13306.1 EIE91886.1 - 0.052 13.2 1.4 0.66 9.6 0.2 2.6 1 1 2 3 3 3 0 Leucine rich repeats (6 copies) Ecm33 PF12454.3 EIE91886.1 - 0.063 13.1 2.6 8.7 6.3 0.1 3.4 1 1 1 2 2 2 0 GPI-anchored cell wall organization protein G-alpha PF00503.15 EIE91887.1 - 3.3e-77 259.7 0.4 4e-77 259.5 0.3 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EIE91887.1 - 2.8e-10 39.6 0.1 7.1e-10 38.4 0.1 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family Radical_SAM PF04055.16 EIE91888.1 - 4.2e-35 121.3 0.1 2.3e-34 118.9 0.0 2.2 2 0 0 2 2 2 1 Radical SAM superfamily UPF0004 PF00919.15 EIE91888.1 - 1.2e-26 92.3 0.1 2.5e-26 91.3 0.1 1.6 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 TRAM PF01938.15 EIE91888.1 - 5.9e-08 32.3 0.0 1.1e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 TRAM domain TAF8_C PF10406.4 EIE91889.1 - 2.2e-14 53.2 0.9 6.4e-14 51.7 0.6 1.9 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.8 EIE91889.1 - 1.4e-08 34.3 0.1 2.3e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated Isochorismatase PF00857.15 EIE91890.1 - 1.6e-36 125.8 0.0 2.8e-36 125.0 0.0 1.4 1 1 0 1 1 1 1 Isochorismatase family AAA_25 PF13481.1 EIE91890.1 - 0.14 11.5 0.0 0.31 10.4 0.0 1.5 2 0 0 2 2 2 0 AAA domain MatP PF06303.7 EIE91892.1 - 0.11 12.3 0.1 0.21 11.4 0.0 1.4 1 1 0 1 1 1 0 Organiser of macrodomain of Terminus of chromosome MFS_1 PF07690.11 EIE91893.1 - 1.1e-26 93.3 64.3 2.2e-16 59.5 14.3 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.1 EIE91893.1 - 3.7e-05 22.3 35.3 0.00015 20.3 7.7 2.9 2 1 1 3 3 3 3 MFS/sugar transport protein RVT_1 PF00078.22 EIE91896.1 - 2.5e-13 49.8 0.2 5e-13 48.8 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MFS_1 PF07690.11 EIE91897.1 - 1.1e-26 93.3 64.3 2.2e-16 59.5 14.3 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.1 EIE91897.1 - 3.7e-05 22.3 35.3 0.00015 20.3 7.7 2.9 2 1 1 3 3 3 3 MFS/sugar transport protein MatP PF06303.7 EIE91898.1 - 0.11 12.3 0.1 0.21 11.4 0.0 1.4 1 1 0 1 1 1 0 Organiser of macrodomain of Terminus of chromosome Isochorismatase PF00857.15 EIE91900.1 - 1.6e-36 125.8 0.0 2.8e-36 125.0 0.0 1.4 1 1 0 1 1 1 1 Isochorismatase family AAA_25 PF13481.1 EIE91900.1 - 0.14 11.5 0.0 0.31 10.4 0.0 1.5 2 0 0 2 2 2 0 AAA domain PAP1 PF08601.5 EIE91901.1 - 4.5e-10 39.7 0.1 4.5e-10 39.7 0.1 3.1 2 1 0 2 2 2 1 Transcription factor PAP1 bZIP_1 PF00170.16 EIE91901.1 - 7e-07 29.1 19.3 7e-07 29.1 13.3 2.5 2 1 0 2 2 2 1 bZIP transcription factor MSV199 PF10553.4 EIE91901.1 - 0.0044 16.8 0.6 0.0081 16.0 0.4 1.3 1 0 0 1 1 1 1 MSV199 domain ATG16 PF08614.6 EIE91901.1 - 0.0075 16.1 17.6 0.014 15.2 12.2 1.4 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) bZIP_2 PF07716.10 EIE91901.1 - 0.014 15.2 19.6 1.4 8.7 13.6 2.5 1 1 0 1 1 1 0 Basic region leucine zipper FRG2 PF15315.1 EIE91901.1 - 0.25 11.2 13.2 0.48 10.3 9.1 1.5 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 SOBP PF15279.1 EIE91901.1 - 9.8 6.4 13.6 15 5.8 9.4 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein DUF3425 PF11905.3 EIE91904.1 - 1.7e-11 44.1 1.5 6e-10 39.1 1.0 2.5 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 EIE91904.1 - 0.00018 21.3 18.5 0.04 13.8 0.4 2.5 2 0 0 2 2 2 2 bZIP transcription factor CENP-L PF13092.1 EIE91905.1 - 3.9e-13 49.5 0.3 9.8e-13 48.1 0.1 1.7 2 0 0 2 2 2 1 Kinetochore complex Sim4 subunit Fta1 SynMuv_product PF06047.6 EIE91906.1 - 6e-46 154.5 3.6 6e-46 154.5 2.5 2.2 2 0 0 2 2 2 1 Ras-induced vulval development antagonist BLVR PF06375.6 EIE91906.1 - 0.35 10.6 23.8 0.19 11.5 11.2 2.4 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) SHD1 PF03983.7 EIE91907.1 - 1.7e-27 94.8 0.0 3.7e-27 93.7 0.0 1.5 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_9 PF14604.1 EIE91907.1 - 2.7e-19 68.4 0.9 9.3e-13 47.5 0.4 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 EIE91907.1 - 3.5e-16 58.3 0.6 3.3e-12 45.6 0.1 3.2 3 0 0 3 3 3 2 SH3 domain SH3_2 PF07653.12 EIE91907.1 - 3.7e-12 45.5 0.2 1.9e-06 27.2 0.2 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_3 PF08239.6 EIE91907.1 - 6.6e-05 23.0 1.9 0.01 16.0 1.7 2.4 2 0 0 2 2 2 1 Bacterial SH3 domain PH_6 PF15406.1 EIE91907.1 - 0.014 15.4 0.0 0.054 13.5 0.0 2.0 1 0 0 1 1 1 0 Pleckstrin homology domain ALMT PF11744.3 EIE91907.1 - 0.092 11.3 2.4 0.16 10.5 1.7 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter Spermine_synth PF01564.12 EIE91908.1 - 7.2e-93 310.0 0.0 9.7e-93 309.6 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_31 PF13847.1 EIE91908.1 - 0.00059 19.4 0.0 0.0011 18.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 EIE91908.1 - 0.00096 18.4 0.8 0.0096 15.1 0.1 2.5 1 1 1 3 3 3 1 O-methyltransferase Methyltransf_30 PF05430.6 EIE91908.1 - 0.0079 15.8 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_18 PF12847.2 EIE91908.1 - 0.048 14.2 0.0 0.085 13.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain AlaDh_PNT_C PF01262.16 EIE91908.1 - 0.088 12.3 0.0 12 5.4 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_12 PF08242.7 EIE91908.1 - 0.093 13.2 0.1 0.41 11.1 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain TBP PF00352.16 EIE91909.1 - 2.1e-70 232.1 0.1 6.9e-35 118.2 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 EIE91909.1 - 0.00012 22.0 0.1 0.64 10.1 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) HMG_box PF00505.14 EIE91910.1 - 6.6e-18 64.7 0.7 1.3e-17 63.8 0.5 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EIE91910.1 - 1e-12 48.1 0.6 2.1e-12 47.1 0.4 1.5 1 0 0 1 1 1 1 HMG-box domain Tol_Tol_Ttg2 PF05494.7 EIE91910.1 - 0.0089 15.5 0.2 0.014 14.9 0.1 1.3 1 0 0 1 1 1 1 Toluene tolerance, Ttg2 NDUFB10 PF10249.4 EIE91910.1 - 0.017 15.2 0.2 0.027 14.6 0.1 1.3 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit 10 RNase_P_pop3 PF08228.6 EIE91911.1 - 7.6e-11 42.0 1.1 8.1e-11 41.9 0.2 1.5 2 0 0 2 2 2 1 RNase P subunit Pop3 Ribosomal_L7Ae PF01248.21 EIE91911.1 - 0.00033 20.1 0.2 0.00061 19.2 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family AOX PF01786.12 EIE91912.1 - 6.7e-13 48.5 0.0 1.3e-12 47.5 0.0 1.4 2 0 0 2 2 2 1 Alternative oxidase DDE_3 PF13358.1 EIE91914.1 - 2.9e-05 23.8 0.0 3.2e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Ras PF00071.17 EIE91915.1 - 1.2e-48 164.5 0.0 1.5e-48 164.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIE91915.1 - 1.5e-15 57.7 0.0 2.9e-15 56.8 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EIE91915.1 - 3.8e-10 39.2 0.0 4.6e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EIE91915.1 - 0.00013 21.1 0.0 0.00017 20.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RNA_helicase PF00910.17 EIE91915.1 - 0.00031 20.8 0.1 0.0015 18.6 0.0 2.0 1 1 0 1 1 1 1 RNA helicase G-alpha PF00503.15 EIE91915.1 - 0.014 14.1 2.5 1.5 7.4 0.1 2.8 2 1 1 3 3 3 0 G-protein alpha subunit Pox_A32 PF04665.7 EIE91915.1 - 0.031 13.5 0.0 0.051 12.8 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_33 PF13671.1 EIE91915.1 - 0.072 12.9 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EIE91915.1 - 0.076 13.1 0.3 0.3 11.2 0.2 2.0 1 1 0 1 1 1 0 AAA domain KaiC PF06745.8 EIE91915.1 - 0.12 11.4 0.1 0.19 10.8 0.1 1.2 1 0 0 1 1 1 0 KaiC ubiquitin PF00240.18 EIE91916.1 - 5e-35 118.7 1.3 6.5e-35 118.3 0.9 1.1 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.12 EIE91916.1 - 9.8e-31 105.1 11.1 1.6e-30 104.4 7.7 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.3 EIE91916.1 - 2.5e-20 71.9 1.0 4e-20 71.2 0.7 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EIE91916.1 - 2.9e-06 27.4 0.2 1e-05 25.6 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EIE91916.1 - 0.00011 21.9 0.0 0.00016 21.4 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EIE91916.1 - 0.003 17.4 0.1 0.0058 16.4 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EIE91916.1 - 0.0045 17.1 0.1 0.0046 17.1 0.0 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 EIE91916.1 - 0.091 12.8 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2870) Plexin_cytopl PF08337.7 EIE91916.1 - 0.16 10.2 0.7 2.8 6.1 0.3 2.0 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain Fer2_3 PF13085.1 EIE91916.1 - 0.22 11.3 2.0 0.92 9.3 0.9 2.1 1 1 1 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain Pkinase PF00069.20 EIE91917.1 - 0.031 13.4 0.0 0.061 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein kinase domain PAM2 PF07145.10 EIE91917.1 - 0.2 11.2 0.1 0.2 11.2 0.1 2.4 2 0 0 2 2 2 0 Ataxin-2 C-terminal region Ribosomal_L28e PF01778.12 EIE91918.1 - 1e-33 116.2 4.1 1.4e-33 115.7 2.8 1.2 1 0 0 1 1 1 1 Ribosomal L28e protein family Big_1 PF02369.11 EIE91918.1 - 0.078 12.8 0.2 0.15 12.0 0.1 1.5 1 1 0 1 1 1 0 Bacterial Ig-like domain (group 1) TYW3 PF02676.9 EIE91919.1 - 1.7e-23 82.8 0.0 2e-23 82.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase TYW3 PIH1 PF08190.7 EIE91920.1 - 7.3e-10 38.7 0.4 1.4e-09 37.9 0.3 1.4 1 1 0 1 1 1 1 pre-RNA processing PIH1/Nop17 RhoGAP PF00620.22 EIE91921.1 - 5.8e-35 120.1 0.1 1.1e-34 119.2 0.1 1.5 1 0 0 1 1 1 1 RhoGAP domain BAR PF03114.13 EIE91922.1 - 2e-26 92.9 0.1 2e-26 92.9 0.1 2.1 3 0 0 3 3 3 1 BAR domain Ribosomal_L7Ae PF01248.21 EIE91922.1 - 2.3e-25 87.9 0.3 4.1e-25 87.1 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 EIE91922.1 - 0.00084 19.2 0.0 0.0019 18.0 0.0 1.6 1 0 0 1 1 1 1 RNase P subunit Pop3 NARP1 PF12569.3 EIE91923.1 - 1.6e-182 607.9 23.8 1.6e-182 607.9 16.5 2.6 2 1 1 3 3 3 1 NMDA receptor-regulated protein 1 TPR_16 PF13432.1 EIE91923.1 - 8.5e-18 64.5 18.8 0.00069 20.2 0.5 9.3 10 1 0 10 10 8 5 Tetratricopeptide repeat TPR_2 PF07719.12 EIE91923.1 - 6.6e-17 59.9 38.7 6.4e-05 22.5 2.0 10.8 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_11 PF13414.1 EIE91923.1 - 3e-16 58.8 35.1 2.3e-06 27.1 2.6 8.9 8 2 2 10 10 10 4 TPR repeat TPR_14 PF13428.1 EIE91923.1 - 3.7e-12 45.7 13.4 0.62 10.8 0.0 10.4 8 2 4 12 12 11 2 Tetratricopeptide repeat TPR_19 PF14559.1 EIE91923.1 - 7.5e-12 45.4 27.9 0.056 13.7 0.2 8.7 8 2 2 10 10 9 5 Tetratricopeptide repeat TPR_9 PF13371.1 EIE91923.1 - 2.3e-09 36.9 0.2 0.0045 16.8 0.1 5.7 6 1 1 7 7 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 EIE91923.1 - 2.3e-09 37.0 21.8 0.0011 18.8 0.1 7.5 6 2 1 7 7 7 2 Tetratricopeptide repeat Apc3 PF12895.2 EIE91923.1 - 1.6e-08 34.5 23.0 0.0055 16.8 0.0 6.5 3 2 3 7 7 7 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 EIE91923.1 - 3.9e-08 32.8 15.6 0.1 12.8 0.0 8.3 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_1 PF00515.23 EIE91923.1 - 6.6e-07 28.6 37.3 0.027 14.0 3.2 8.9 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_7 PF13176.1 EIE91923.1 - 3.2e-06 26.5 7.3 0.071 12.9 0.1 6.8 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_8 PF13181.1 EIE91923.1 - 2e-05 24.0 29.4 0.0011 18.6 0.6 8.8 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_15 PF13429.1 EIE91923.1 - 0.00034 19.7 0.7 0.00034 19.7 0.5 4.0 3 1 3 6 6 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 EIE91923.1 - 0.0018 18.6 19.5 9.3 6.9 0.0 9.0 10 0 0 10 10 10 0 Tetratricopeptide repeat MIT PF04212.13 EIE91923.1 - 0.0089 15.8 13.8 2.7 7.9 0.1 6.4 5 1 0 6 6 6 1 MIT (microtubule interacting and transport) domain Fis1_TPR_C PF14853.1 EIE91923.1 - 0.016 15.0 12.6 0.022 14.6 0.2 5.7 6 0 0 6 6 5 0 Fis1 C-terminal tetratricopeptide repeat FAD_binding_1 PF00667.15 EIE91924.1 - 1.1e-46 159.0 0.0 1.7e-46 158.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 EIE91924.1 - 5.6e-09 36.5 0.0 1.4e-08 35.2 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_1 PF00258.20 EIE91924.1 - 1e-07 32.0 0.0 2e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin Abhydrolase_3 PF07859.8 EIE91925.1 - 1.7e-54 184.6 0.3 2e-54 184.3 0.2 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EIE91925.1 - 3.9e-10 39.3 0.1 9.4e-10 38.0 0.1 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.23 EIE91925.1 - 0.00038 19.3 0.0 0.00054 18.8 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 EIE91925.1 - 0.0038 16.9 0.0 0.014 15.1 0.0 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family DLH PF01738.13 EIE91925.1 - 0.012 14.8 0.0 0.049 12.9 0.0 1.8 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_6 PF12697.2 EIE91925.1 - 0.025 14.4 0.2 0.038 13.8 0.1 1.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EIE91925.1 - 0.043 12.6 0.1 0.094 11.5 0.0 1.6 2 0 0 2 2 2 0 Chlorophyllase enzyme Ras PF00071.17 EIE91927.1 - 1.9e-39 134.6 0.1 2.3e-39 134.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIE91927.1 - 8e-12 45.7 0.1 3.1e-11 43.8 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EIE91927.1 - 3.3e-08 32.9 0.1 4.5e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EIE91927.1 - 0.011 15.2 0.0 0.013 14.9 0.0 1.1 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Pkinase PF00069.20 EIE91928.1 - 2.3e-26 92.5 0.0 3.8e-26 91.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE91928.1 - 3.2e-17 62.4 0.0 4.9e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Hexokinase_2 PF03727.11 EIE91928.1 - 0.033 13.3 0.3 7.5 5.6 0.0 2.2 2 0 0 2 2 2 0 Hexokinase Kinase-like PF14531.1 EIE91928.1 - 0.045 12.7 0.0 0.075 11.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like DDE_2 PF02914.10 EIE91928.1 - 0.073 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage Mu transposase BAR PF03114.13 EIE91929.1 - 1.1e-26 93.7 3.3 1.8e-26 93.1 2.3 1.2 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.1 EIE91929.1 - 9.3e-15 53.9 0.0 1.6e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EIE91929.1 - 2.1e-14 52.6 0.0 3.5e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EIE91929.1 - 2.9e-12 45.8 0.0 5.6e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Vps5 PF09325.5 EIE91929.1 - 0.015 14.5 1.0 0.028 13.6 0.7 1.4 1 0 0 1 1 1 0 Vps5 C terminal like DAOA PF15199.1 EIE91929.1 - 0.063 13.9 0.0 0.18 12.4 0.0 1.7 1 0 0 1 1 1 0 D-amino acid oxidase activator Ribosomal_L5_C PF00673.16 EIE91930.1 - 2.3e-24 84.9 0.0 5.6e-24 83.6 0.0 1.7 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L1 PF00687.16 EIE91930.1 - 7.1e-24 84.3 2.0 3.5e-23 82.1 1.4 2.0 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family Ribosomal_L5 PF00281.14 EIE91930.1 - 2.2e-06 27.3 0.0 6.5e-06 25.8 0.0 1.8 1 0 0 1 1 1 1 Ribosomal protein L5 Phage_30_8 PF06019.6 EIE91931.1 - 0.063 12.9 0.0 0.078 12.6 0.0 1.1 1 0 0 1 1 1 0 Phage GP30.8 protein Kinesin PF00225.18 EIE91932.1 - 2.3e-79 266.5 1.5 2.3e-79 266.5 1.1 2.4 2 1 0 2 2 2 1 Kinesin motor domain FUSC PF04632.7 EIE91932.1 - 0.011 14.2 1.6 0.011 14.2 0.2 1.6 2 0 0 2 2 2 0 Fusaric acid resistance protein family HALZ PF02183.13 EIE91932.1 - 0.38 10.5 29.6 0.043 13.5 3.1 4.2 2 1 2 4 4 4 0 Homeobox associated leucine zipper Atrophin-1 PF03154.10 EIE91933.1 - 0.0039 15.4 0.1 0.0043 15.2 0.1 1.0 1 0 0 1 1 1 1 Atrophin-1 family CAP_N PF01213.14 EIE91933.1 - 0.048 12.9 0.7 0.075 12.3 0.5 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF4239 PF14023.1 EIE91933.1 - 0.065 12.5 0.3 0.088 12.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) Lipase_3 PF01764.20 EIE91934.1 - 2.5e-18 66.0 0.0 7.8e-18 64.4 0.0 1.8 2 0 0 2 2 2 1 Lipase (class 3) RRM_1 PF00076.17 EIE91935.1 - 4.4e-33 112.7 0.0 1.3e-20 72.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE91935.1 - 8.4e-21 73.7 0.0 1.9e-13 50.1 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIE91935.1 - 1.7e-11 43.7 0.0 4e-06 26.5 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 EIE91936.1 - 0.087 12.7 0.0 14 5.7 0.0 2.6 2 0 0 2 2 2 0 WD domain, G-beta repeat Rotamase PF00639.16 EIE91937.1 - 2.3e-06 28.2 5.2 0.034 14.8 0.0 2.5 1 1 2 3 3 3 2 PPIC-type PPIASE domain Rotamase_3 PF13616.1 EIE91937.1 - 2.4e-05 24.5 4.9 0.012 15.8 3.4 2.2 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 EIE91937.1 - 0.0093 16.5 0.5 0.014 15.9 0.4 1.4 1 1 0 1 1 1 1 PPIC-type PPIASE domain DUF3137 PF11335.3 EIE91937.1 - 0.022 14.4 0.0 0.026 14.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3137) FAM176 PF14851.1 EIE91938.1 - 0.36 10.5 2.5 0.49 10.0 1.7 1.2 1 0 0 1 1 1 0 FAM176 family Pkinase PF00069.20 EIE91939.1 - 7.4e-32 110.5 0.0 9.9e-32 110.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE91939.1 - 1.2e-09 37.6 0.0 1.7e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase YrbL-PhoP_reg PF10707.4 EIE91939.1 - 0.031 13.5 0.2 0.062 12.6 0.0 1.6 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL vMSA PF00695.14 EIE91939.1 - 0.077 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Peptidase_M13 PF01431.16 EIE91940.1 - 4.7e-70 234.9 0.0 9e-70 234.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13_N PF05649.8 EIE91940.1 - 1.5e-69 234.9 0.0 2.4e-69 234.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M48 PF01435.13 EIE91940.1 - 0.00067 19.2 0.0 0.0016 18.0 0.0 1.5 2 0 0 2 2 2 1 Peptidase family M48 VacJ PF04333.8 EIE91940.1 - 0.021 14.2 0.0 0.044 13.2 0.0 1.4 1 0 0 1 1 1 0 VacJ like lipoprotein Peptidase_MA_2 PF13485.1 EIE91940.1 - 0.033 14.2 0.0 0.07 13.1 0.0 1.6 1 0 0 1 1 1 0 Peptidase MA superfamily RasGAP PF00616.14 EIE91943.1 - 1.8e-39 135.4 2.0 2.6e-39 134.9 0.2 2.2 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.1 EIE91943.1 - 5.8e-17 61.9 0.3 1.8e-16 60.3 0.2 1.9 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.15 EIE91943.1 - 7.3e-06 25.5 0.7 2.5e-05 23.8 0.3 2.0 2 0 0 2 2 2 1 CRAL/TRIO domain MOR2-PAG1_C PF14225.1 EIE91943.1 - 0.0013 18.5 0.5 0.0047 16.7 0.0 2.2 2 0 0 2 2 2 1 Cell morphogenesis C-terminal RCC1 PF00415.13 EIE91944.1 - 1.1e-72 240.0 10.5 1.3e-13 50.9 0.0 7.7 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EIE91944.1 - 1e-46 155.5 27.4 1.8e-10 40.1 2.0 8.4 8 0 0 8 8 8 8 Regulator of chromosome condensation (RCC1) repeat Methyltransf_11 PF08241.7 EIE91945.1 - 5.2e-11 42.8 0.0 9.3e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIE91945.1 - 8.8e-10 38.5 0.0 1.1e-09 38.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIE91945.1 - 2.4e-07 30.4 0.0 4.8e-07 29.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIE91945.1 - 1.2e-06 28.8 0.0 2.2e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIE91945.1 - 3.3e-05 24.1 0.0 8e-05 22.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIE91945.1 - 0.00031 19.9 0.0 0.00076 18.6 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EIE91945.1 - 0.002 18.6 0.1 0.0059 17.1 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIE91945.1 - 0.0035 17.3 0.0 0.0064 16.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 EIE91945.1 - 0.016 14.5 0.0 0.048 13.0 0.0 1.7 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_8 PF05148.10 EIE91945.1 - 0.03 13.9 0.1 0.26 10.8 0.0 2.0 1 1 0 1 1 1 0 Hypothetical methyltransferase CMAS PF02353.15 EIE91945.1 - 0.053 12.6 0.0 0.24 10.4 0.0 1.8 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.13 EIE91945.1 - 0.075 12.2 0.0 0.27 10.4 0.0 1.7 1 1 0 1 1 1 0 O-methyltransferase PCMT PF01135.14 EIE91945.1 - 0.11 12.0 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.8 EIE91945.1 - 0.15 11.1 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF2205 PF10224.4 EIE91947.1 - 0.0065 16.0 2.5 0.014 14.9 1.7 1.5 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) Sipho_Gp157 PF05565.6 EIE91947.1 - 0.0079 15.7 0.2 0.012 15.2 0.2 1.2 1 0 0 1 1 1 1 Siphovirus Gp157 DUF972 PF06156.8 EIE91947.1 - 0.024 14.9 0.7 0.033 14.5 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) TBPIP PF07106.8 EIE91947.1 - 0.032 13.7 2.6 0.04 13.4 1.8 1.1 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF2935 PF11155.3 EIE91947.1 - 0.04 13.9 0.7 0.056 13.5 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) DUF3513 PF12026.3 EIE91947.1 - 0.051 13.1 4.5 0.076 12.5 3.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3513) Tweety PF04906.8 EIE91947.1 - 0.23 9.8 1.6 0.31 9.3 1.1 1.1 1 0 0 1 1 1 0 Tweety EMP24_GP25L PF01105.19 EIE91947.1 - 0.45 10.2 5.2 0.74 9.5 3.6 1.3 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD SseC PF04888.7 EIE91947.1 - 4.7 6.4 11.8 4.9 6.3 7.5 1.4 1 1 1 2 2 2 0 Secretion system effector C (SseC) like family Peptidase_S8 PF00082.17 EIE91948.1 - 9.8e-49 165.9 4.7 2e-48 164.9 3.3 1.6 1 0 0 1 1 1 1 Subtilase family PA PF02225.17 EIE91948.1 - 7.1e-17 60.9 0.5 2.1e-16 59.4 0.4 1.8 1 0 0 1 1 1 1 PA domain DUF1034 PF06280.7 EIE91948.1 - 1.2e-09 38.5 1.7 2.5e-09 37.5 0.2 2.3 2 0 0 2 2 2 1 Fn3-like domain (DUF1034) Motile_Sperm PF00635.21 EIE91948.1 - 0.018 14.6 0.5 10 5.8 0.2 3.4 3 0 0 3 3 3 0 MSP (Major sperm protein) domain MYCBPAP PF14646.1 EIE91948.1 - 0.043 12.5 0.0 0.065 11.9 0.0 1.2 1 0 0 1 1 1 0 MYCBP-associated protein family DUF1573 PF07610.6 EIE91948.1 - 0.059 12.9 1.5 1.6 8.3 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1573) HATPase_c PF02518.21 EIE91949.1 - 1.3e-13 50.6 0.0 2.5e-13 49.7 0.0 1.5 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EIE91949.1 - 5.6e-08 32.5 0.0 7.3e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase BCDHK_Adom3 PF10436.4 EIE91949.1 - 1.4e-07 31.2 0.4 2.8e-07 30.1 0.3 1.5 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c_2 PF13581.1 EIE91949.1 - 0.00022 21.0 0.0 0.00029 20.6 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HTH_3 PF01381.17 EIE91949.1 - 0.13 12.0 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix CN_hydrolase PF00795.17 EIE91950.1 - 4.5e-26 91.3 0.0 7e-26 90.7 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.12 EIE91950.1 - 9.6e-25 86.8 0.0 2.2e-24 85.6 0.0 1.5 1 1 0 1 1 1 1 NAD synthase Asn_synthase PF00733.16 EIE91950.1 - 0.018 14.5 0.0 0.037 13.5 0.0 1.4 1 0 0 1 1 1 0 Asparagine synthase Spb1_C PF07780.7 EIE91951.1 - 1.1e-48 165.5 18.0 1.1e-48 165.5 12.5 4.5 2 1 0 3 3 3 1 Spb1 C-terminal domain DUF3381 PF11861.3 EIE91951.1 - 4.7e-47 159.4 15.2 4.7e-47 159.4 10.6 5.3 3 1 3 6 6 6 1 Domain of unknown function (DUF3381) FtsJ PF01728.14 EIE91951.1 - 2e-24 86.6 0.0 4.4e-24 85.4 0.0 1.7 1 0 0 1 1 1 1 FtsJ-like methyltransferase Ctr PF04145.10 EIE91952.1 - 0.048 13.7 0.1 0.087 12.8 0.0 1.4 1 0 0 1 1 1 0 Ctr copper transporter family AAA_2 PF07724.9 EIE91953.1 - 4.2e-55 186.2 3.6 3.4e-51 173.5 0.0 3.2 4 0 0 4 4 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.24 EIE91953.1 - 3.8e-28 98.3 0.0 4.5e-15 56.0 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 EIE91953.1 - 2.6e-24 84.8 2.8 5.6e-24 83.8 0.1 3.1 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 EIE91953.1 - 7.7e-20 71.0 0.6 1.6e-10 40.8 0.0 4.2 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EIE91953.1 - 1e-14 54.9 2.4 4.1e-06 26.9 0.0 4.7 3 3 1 5 5 4 2 AAA ATPase domain Clp_N PF02861.15 EIE91953.1 - 3.2e-11 42.9 0.0 3.7e-10 39.5 0.0 2.6 2 0 0 2 2 2 1 Clp amino terminal domain AAA_22 PF13401.1 EIE91953.1 - 5.1e-10 39.6 0.1 0.0017 18.5 0.0 3.8 3 2 0 3 3 3 2 AAA domain Sigma54_activat PF00158.21 EIE91953.1 - 8.3e-10 38.3 0.0 3.6e-06 26.5 0.0 2.8 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_14 PF13173.1 EIE91953.1 - 4.2e-08 33.1 0.0 0.01 15.7 0.0 3.6 3 2 0 3 3 2 2 AAA domain IstB_IS21 PF01695.12 EIE91953.1 - 3.7e-07 29.7 0.0 0.039 13.3 0.0 3.0 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.16 EIE91953.1 - 8.3e-07 28.3 0.0 0.04 13.0 0.1 3.5 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 EIE91953.1 - 9e-07 29.7 8.4 0.016 16.0 0.0 4.4 3 2 1 4 4 4 2 AAA domain AAA_19 PF13245.1 EIE91953.1 - 4.2e-05 23.2 0.0 0.038 13.7 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain AAA_18 PF13238.1 EIE91953.1 - 4.5e-05 23.7 7.8 0.011 16.0 0.0 3.9 4 1 0 4 4 2 2 AAA domain MobB PF03205.9 EIE91953.1 - 7.4e-05 22.4 0.0 0.078 12.6 0.0 2.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 EIE91953.1 - 0.00013 21.6 0.0 0.033 13.8 0.0 2.7 2 0 0 2 2 2 1 NACHT domain RNA_helicase PF00910.17 EIE91953.1 - 0.00021 21.4 0.0 0.8 9.9 0.0 2.9 2 0 0 2 2 2 2 RNA helicase Torsin PF06309.6 EIE91953.1 - 0.00026 20.8 0.0 0.00081 19.2 0.0 1.8 1 0 0 1 1 1 1 Torsin AAA_28 PF13521.1 EIE91953.1 - 0.0007 19.5 0.1 3 7.7 0.0 3.9 3 0 0 3 3 3 1 AAA domain Arch_ATPase PF01637.13 EIE91953.1 - 0.00098 18.8 9.7 0.14 11.8 0.0 4.7 3 2 1 4 4 3 1 Archaeal ATPase ABC_tran PF00005.22 EIE91953.1 - 0.0012 19.1 0.1 0.36 11.1 0.0 3.2 3 0 0 3 3 2 1 ABC transporter AAA_10 PF12846.2 EIE91953.1 - 0.0014 18.1 0.1 0.87 8.9 0.0 3.8 3 1 1 4 4 4 1 AAA-like domain AAA_24 PF13479.1 EIE91953.1 - 0.0022 17.5 0.0 0.27 10.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 EIE91953.1 - 0.0034 17.2 0.1 0.31 10.8 0.0 3.5 2 1 0 3 3 3 1 Type III restriction enzyme, res subunit DUF258 PF03193.11 EIE91953.1 - 0.0043 16.2 0.0 2.2 7.4 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 EIE91953.1 - 0.0045 16.3 0.1 2.7 7.3 0.0 3.4 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.18 EIE91953.1 - 0.0061 16.5 0.0 0.68 9.9 0.0 3.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_3 PF07726.6 EIE91953.1 - 0.0061 16.1 0.0 2.4 7.7 0.0 2.8 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 EIE91953.1 - 0.0095 14.8 0.0 0.2 10.5 0.0 2.6 2 1 0 2 2 2 1 Type II/IV secretion system protein SRP54 PF00448.17 EIE91953.1 - 0.011 15.2 0.0 1.1 8.6 0.0 2.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NTPase_1 PF03266.10 EIE91953.1 - 0.013 15.2 0.0 4.8 6.8 0.0 3.5 3 0 0 3 3 3 0 NTPase DUF458 PF04308.7 EIE91953.1 - 0.015 15.0 1.9 0.07 12.8 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF458) ATP_bind_1 PF03029.12 EIE91953.1 - 0.015 14.8 0.0 1.2 8.6 0.0 3.3 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein DNA_pol3_delta2 PF13177.1 EIE91953.1 - 0.018 14.7 0.0 5.3 6.6 0.0 3.6 4 0 0 4 4 4 0 DNA polymerase III, delta subunit PduV-EutP PF10662.4 EIE91953.1 - 0.026 14.0 0.0 1.6 8.2 0.0 2.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.1 EIE91953.1 - 0.027 14.3 0.0 4.7 7.0 0.0 3.2 3 0 0 3 3 2 0 AAA domain UPF0079 PF02367.12 EIE91953.1 - 0.065 12.8 0.0 18 5.0 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 BLOC1_2 PF10046.4 EIE91953.1 - 0.07 13.2 5.7 0.098 12.8 2.3 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 AAA_29 PF13555.1 EIE91953.1 - 0.15 11.6 0.0 7.6 6.1 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF1192 PF06698.6 EIE91953.1 - 0.25 11.1 7.8 0.76 9.6 0.1 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) p450 PF00067.17 EIE91954.1 - 1.7e-42 145.5 0.0 1.8e-42 145.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_3 PF07859.8 EIE91955.1 - 6.2e-64 215.4 0.1 7.9e-64 215.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EIE91955.1 - 1e-09 37.5 0.0 1.6e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) COesterase PF00135.23 EIE91955.1 - 1e-08 34.3 0.6 4.6e-08 32.2 0.4 1.9 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 EIE91955.1 - 1.5e-07 30.8 0.1 3.1e-07 29.8 0.0 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EIE91955.1 - 0.0017 18.1 0.0 0.0033 17.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EIE91955.1 - 0.002 17.0 0.1 0.0071 15.2 0.0 1.8 2 0 0 2 2 2 1 Chlorophyllase enzyme Ras PF00071.17 EIE91956.1 - 3.2e-52 176.1 0.2 3.6e-52 175.9 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIE91956.1 - 4.9e-17 62.5 0.0 6.6e-17 62.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIE91956.1 - 1e-08 34.6 0.0 1.3e-08 34.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EIE91956.1 - 6.6e-05 22.8 0.0 8.6e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EIE91956.1 - 0.0013 18.1 0.0 0.0016 17.9 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 EIE91956.1 - 0.019 14.4 0.1 0.13 11.7 0.0 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 EIE91956.1 - 0.022 14.9 0.0 0.03 14.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 EIE91956.1 - 0.031 13.4 0.1 0.072 12.2 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 EIE91956.1 - 0.041 13.4 0.2 0.33 10.5 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain Bmp PF02608.9 EIE91956.1 - 0.045 12.4 0.1 0.056 12.1 0.1 1.1 1 0 0 1 1 1 0 Basic membrane protein AAA_28 PF13521.1 EIE91956.1 - 0.061 13.2 0.1 0.21 11.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EIE91956.1 - 0.078 12.9 0.1 0.13 12.2 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.9 EIE91956.1 - 0.099 12.3 0.0 0.24 11.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) NAC PF01849.13 EIE91957.1 - 0.044 13.3 0.1 0.14 11.7 0.0 1.8 2 0 0 2 2 2 0 NAC domain DAO PF01266.19 EIE91958.1 - 4.6e-20 71.8 0.0 6.8e-09 35.0 0.0 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.19 EIE91958.1 - 1.9e-19 70.0 0.2 5.1e-19 68.6 0.1 1.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EIE91958.1 - 2.6e-15 56.1 0.1 6.3e-15 54.9 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EIE91958.1 - 1.7e-08 33.7 1.6 1.1e-05 24.4 0.8 2.1 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.2 EIE91958.1 - 2.5e-07 30.1 0.1 5.2e-06 25.7 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EIE91958.1 - 4.3e-07 30.0 0.1 1.2e-06 28.5 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EIE91958.1 - 1.3e-05 25.0 1.6 0.0039 16.9 0.1 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 EIE91958.1 - 0.00027 20.0 0.3 0.00043 19.4 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EIE91958.1 - 0.00048 18.7 0.8 0.005 15.3 0.4 2.0 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.17 EIE91958.1 - 0.00062 18.7 3.3 0.0039 16.1 0.6 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EIE91958.1 - 0.0008 19.5 0.1 0.39 10.7 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EIE91958.1 - 0.00094 18.3 0.1 0.0019 17.3 0.1 1.4 1 0 0 1 1 1 1 Thi4 family GDI PF00996.13 EIE91958.1 - 0.0013 17.1 0.0 0.16 10.2 0.0 2.1 2 0 0 2 2 2 1 GDP dissociation inhibitor Lycopene_cycl PF05834.7 EIE91958.1 - 0.0022 16.9 1.6 0.041 12.7 0.2 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.22 EIE91958.1 - 0.0035 17.7 3.0 0.021 15.2 0.9 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EIE91958.1 - 0.014 15.0 1.1 0.023 14.3 0.8 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 EIE91958.1 - 0.015 14.7 0.1 0.035 13.5 0.0 1.7 2 0 0 2 2 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.1 EIE91958.1 - 0.026 14.7 0.0 0.048 13.9 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding ThiF PF00899.16 EIE91958.1 - 0.027 14.2 0.7 0.092 12.5 0.2 2.0 2 0 0 2 2 2 0 ThiF family Methyltransf_18 PF12847.2 EIE91958.1 - 0.043 14.4 0.0 0.15 12.6 0.0 2.0 2 0 0 2 2 1 0 Methyltransferase domain Trp_halogenase PF04820.9 EIE91958.1 - 0.054 12.1 4.2 0.15 10.6 0.7 2.1 2 0 0 2 2 2 0 Tryptophan halogenase TrkA_N PF02254.13 EIE91958.1 - 0.077 12.9 0.0 0.24 11.4 0.1 1.8 2 0 0 2 2 1 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.9 EIE91958.1 - 0.095 12.0 0.1 0.18 11.1 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EIE91958.1 - 0.096 12.4 0.5 0.21 11.3 0.4 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus IlvN PF07991.7 EIE91958.1 - 0.1 11.9 0.1 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Strep_67kDa_ant PF06100.6 EIE91958.1 - 0.11 10.7 1.0 0.69 8.2 0.0 2.4 3 0 0 3 3 3 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family AlaDh_PNT_C PF01262.16 EIE91958.1 - 0.12 11.9 0.5 0.21 11.1 0.4 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Ras PF00071.17 EIE91959.1 - 1.7e-12 47.0 0.0 1.9e-12 46.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Ras PF00071.17 EIE91960.1 - 6.6e-10 38.6 0.1 6.9e-10 38.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIE91960.1 - 0.0046 17.4 0.1 0.005 17.3 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein AAA_22 PF13401.1 EIE91960.1 - 0.0079 16.3 0.0 0.0081 16.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EIE91960.1 - 0.046 13.2 0.5 0.086 12.3 0.2 1.6 1 1 1 2 2 2 0 P-loop containing region of AAA domain DUF258 PF03193.11 EIE91960.1 - 0.047 12.8 0.0 0.047 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DAP3 PF10236.4 EIE91960.1 - 0.061 12.2 0.0 0.075 11.9 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 PduV-EutP PF10662.4 EIE91960.1 - 0.079 12.4 0.0 0.09 12.2 0.0 1.1 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.17 EIE91960.1 - 0.11 12.7 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.12 EIE91960.1 - 0.12 11.7 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 IstB-like ATP binding protein Abhydrolase_3 PF07859.8 EIE91961.1 - 1.6e-55 187.9 0.0 2e-55 187.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EIE91961.1 - 6.1e-07 28.8 0.0 1.2e-06 27.9 0.0 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.23 EIE91961.1 - 0.004 15.9 0.0 0.0057 15.4 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 EIE91961.1 - 0.069 12.9 0.0 0.15 11.7 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EIE91961.1 - 0.074 11.9 0.0 0.25 10.1 0.0 1.7 2 0 0 2 2 2 0 Chlorophyllase enzyme DUF1011 PF06237.7 EIE91962.1 - 0.096 12.5 0.1 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1011) Ras PF00071.17 EIE91963.1 - 6.4e-23 80.9 0.2 7e-20 71.0 0.0 2.0 2 0 0 2 2 2 2 Ras family Miro PF08477.8 EIE91963.1 - 0.0059 17.1 0.3 0.15 12.5 0.0 2.2 1 1 1 2 2 2 1 Miro-like protein RNA_helicase PF00910.17 EIE91963.1 - 0.066 13.3 0.0 0.097 12.8 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.1 EIE91963.1 - 0.085 12.4 0.2 0.74 9.3 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_5 PF07728.9 EIE91963.1 - 0.14 11.9 0.0 0.23 11.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Abhydrolase_3 PF07859.8 EIE91964.1 - 1.4e-63 214.3 0.0 1.7e-63 214.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EIE91964.1 - 4.6e-09 35.5 0.6 2.2e-08 33.2 0.4 1.9 1 1 0 1 1 1 1 Carboxylesterase family DUF2424 PF10340.4 EIE91964.1 - 1.8e-07 30.1 0.1 4.5e-07 28.8 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Peptidase_S9 PF00326.16 EIE91964.1 - 4.8e-07 29.2 0.1 1e-06 28.1 0.0 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.2 EIE91964.1 - 0.00034 19.5 0.1 0.0015 17.4 0.0 1.8 2 0 0 2 2 2 1 Chlorophyllase enzyme Abhydrolase_5 PF12695.2 EIE91964.1 - 0.00047 19.9 0.0 0.00087 19.0 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family RHSP PF07999.6 EIE91964.1 - 0.097 11.2 0.0 0.14 10.6 0.0 1.2 1 0 0 1 1 1 0 Retrotransposon hot spot protein DUF1541 PF07563.6 EIE91965.1 - 0.14 11.8 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1541) p450 PF00067.17 EIE91967.1 - 6.1e-74 249.1 0.0 7.4e-74 248.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2404 PF10296.4 EIE91969.1 - 6.4e-12 45.4 0.0 9.8e-12 44.8 0.0 1.3 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) NIF PF03031.13 EIE91970.1 - 1.8e-27 95.9 0.1 3.6e-27 94.9 0.1 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.2 EIE91970.1 - 5.2e-06 26.2 0.1 1.1e-05 25.1 0.1 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 EIE91970.1 - 7.5e-05 22.8 0.6 0.00022 21.2 0.0 2.1 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain RAP1 PF07218.6 EIE91970.1 - 0.78 7.7 23.2 1.3 6.9 16.1 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) FAM60A PF15396.1 EIE91970.1 - 1.4 8.5 13.3 2.9 7.5 9.2 1.5 1 0 0 1 1 1 0 Protein Family FAM60A Macoilin PF09726.4 EIE91970.1 - 1.9 6.6 23.4 2.8 6.1 16.2 1.2 1 0 0 1 1 1 0 Transmembrane protein DNA_pol_viral_N PF00242.12 EIE91970.1 - 6.2 5.7 19.6 9.4 5.1 13.6 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain rve PF00665.21 EIE91975.1 - 1.8e-22 79.6 0.0 4.5e-22 78.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE91975.1 - 1.4e-15 57.2 0.1 2.8e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.12 EIE91975.1 - 8.2e-09 35.4 0.1 2.3e-08 34.0 0.1 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein Chromo PF00385.19 EIE91975.1 - 8.6e-08 31.7 0.2 2.1e-07 30.5 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 EIE91975.1 - 0.00047 19.5 1.6 0.0015 17.9 1.1 1.9 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger DDE_Tnp_IS1595 PF12762.2 EIE91976.1 - 2.3e-06 27.5 0.1 4.1e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 ISXO2-like transposase domain USP7_ICP0_bdg PF12436.3 EIE91977.1 - 0.12 11.5 0.1 0.17 11.1 0.0 1.3 1 1 0 1 1 1 0 ICP0-binding domain of Ubiquitin-specific protease 7 HTH_Tnp_Tc3_2 PF01498.13 EIE91978.1 - 5.2e-05 23.2 2.4 0.00014 21.8 1.6 1.9 1 1 1 2 2 2 1 Transposase DDE_3 PF13358.1 EIE91978.1 - 0.077 12.7 0.0 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 DDE superfamily endonuclease HTH_Tnp_4 PF13613.1 EIE91978.1 - 0.097 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE91979.1 - 0.00016 21.6 1.0 0.00025 21.0 0.6 1.5 1 1 0 1 1 1 1 Transposase DDE_Tnp_ISAZ013 PF07592.6 EIE91979.1 - 0.14 10.8 0.1 0.14 10.8 0.1 1.0 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain RVT_1 PF00078.22 EIE91980.1 - 6.7e-13 48.4 0.2 2.3e-12 46.7 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.12 EIE91980.1 - 1.5e-06 28.1 0.2 1.5e-06 28.1 0.1 2.8 2 0 0 2 2 2 1 Retrotransposon gag protein SR-25 PF10500.4 EIE91980.1 - 1.2 8.5 18.8 3.4 7.0 13.0 1.7 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein rve PF00665.21 EIE91981.1 - 1.1e-05 25.4 0.0 1.7e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 EIE91981.1 - 0.00036 19.9 0.0 0.00085 18.8 0.0 1.6 2 0 0 2 2 2 1 Integrase core domain ANTH PF07651.11 EIE91981.1 - 0.072 11.7 0.0 0.078 11.6 0.0 1.1 1 0 0 1 1 1 0 ANTH domain rve PF00665.21 EIE91982.1 - 1.9e-24 86.0 0.0 5.9e-24 84.4 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE91982.1 - 6.9e-17 61.5 0.0 1.4e-16 60.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE91982.1 - 7.9e-11 41.4 0.6 2.7e-10 39.7 0.4 2.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 EIE91982.1 - 0.00012 21.4 0.1 0.00031 20.0 0.1 1.8 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Asp_protease_2 PF13650.1 EIE91982.1 - 0.00028 21.3 0.2 0.00086 19.7 0.2 1.9 1 0 0 1 1 1 1 Aspartyl protease UBN2_2 PF14227.1 EIE91982.1 - 0.004 16.7 1.2 0.069 12.7 0.0 2.8 3 0 0 3 3 3 1 gag-polypeptide of LTR copia-type rve_3 PF13683.1 EIE91982.1 - 0.027 13.9 0.0 0.09 12.3 0.0 2.0 1 0 0 1 1 1 0 Integrase core domain UBN2 PF14223.1 EIE91982.1 - 0.032 14.0 0.4 0.094 12.5 0.0 2.0 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type Asp_protease PF09668.5 EIE91982.1 - 0.053 13.0 0.1 0.15 11.6 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.1 EIE91982.1 - 0.15 11.9 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Chromo PF00385.19 EIE91983.1 - 3e-09 36.4 0.8 4.4e-09 35.8 0.1 1.6 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 EIE91983.1 - 0.045 13.4 1.1 0.083 12.6 0.8 1.5 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain Retrotrans_gag PF03732.12 EIE91985.1 - 0.0092 16.0 4.3 0.0093 16.0 0.1 2.8 3 1 0 3 3 3 1 Retrotransposon gag protein DUF342 PF03961.8 EIE91985.1 - 0.026 12.9 2.7 0.038 12.4 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) FlxA PF14282.1 EIE91985.1 - 0.13 12.2 5.7 1.1 9.2 4.1 2.2 1 1 0 1 1 1 0 FlxA-like protein IncA PF04156.9 EIE91985.1 - 0.37 10.3 5.8 0.63 9.6 4.0 1.3 1 0 0 1 1 1 0 IncA protein BLOC1_2 PF10046.4 EIE91985.1 - 0.64 10.1 5.7 4.5 7.4 1.4 2.6 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 V-SNARE PF05008.10 EIE91985.1 - 8.3 6.6 14.4 0.16 12.1 4.5 2.3 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus V_ATPase_I PF01496.14 EIE91985.1 - 9.2 3.9 8.2 14 3.3 5.3 1.4 1 1 0 2 2 2 0 V-type ATPase 116kDa subunit family BLYB PF05289.6 EIE91986.1 - 0.034 13.9 0.1 0.093 12.5 0.1 1.8 1 0 0 1 1 1 0 Borrelia hemolysin accessory protein HTH_Tnp_Tc3_2 PF01498.13 EIE91987.1 - 1.4e-09 37.8 1.9 1.7e-09 37.6 0.5 1.8 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.1 EIE91987.1 - 0.0034 16.9 0.0 0.008 15.8 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.1 EIE91987.1 - 0.011 15.8 0.0 0.023 14.8 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix HTH_30 PF13556.1 EIE91987.1 - 0.014 14.9 0.0 0.12 12.0 0.0 2.1 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain DDE_3 PF13358.1 EIE91987.1 - 0.058 13.1 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 DDE superfamily endonuclease DDE_3 PF13358.1 EIE91988.1 - 8.1e-17 61.3 0.0 1.3e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE91988.1 - 3.7e-10 39.7 2.7 5e-09 36.0 0.9 2.4 2 0 0 2 2 2 1 Transposase HTH_IclR PF09339.5 EIE91988.1 - 0.00017 21.0 0.0 0.00038 19.9 0.0 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_11 PF08279.7 EIE91988.1 - 0.00077 19.0 0.0 0.0023 17.5 0.0 1.7 1 0 0 1 1 1 1 HTH domain HTH_7 PF02796.10 EIE91988.1 - 0.0066 16.2 0.0 0.051 13.4 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_32 PF13565.1 EIE91988.1 - 0.0071 17.1 0.5 6.9 7.5 0.0 2.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.1 EIE91988.1 - 0.0092 15.6 0.0 0.023 14.3 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_36 PF13730.1 EIE91988.1 - 0.011 15.8 0.1 0.4 10.8 0.0 3.0 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_17 PF12728.2 EIE91988.1 - 0.013 15.7 0.0 0.026 14.7 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_24 PF13412.1 EIE91988.1 - 0.017 14.4 0.0 0.039 13.3 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding UPF0122 PF04297.9 EIE91988.1 - 0.02 14.8 0.0 0.049 13.6 0.0 1.6 1 0 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like MarR_2 PF12802.2 EIE91988.1 - 0.023 14.3 0.0 0.042 13.5 0.0 1.4 1 0 0 1 1 1 0 MarR family HTH_AsnC-type PF13404.1 EIE91988.1 - 0.031 13.7 0.0 0.065 12.7 0.0 1.5 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Sigma70_r4 PF04545.11 EIE91988.1 - 0.037 13.3 0.0 0.083 12.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_38 PF13936.1 EIE91988.1 - 0.042 13.3 0.0 0.09 12.3 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.1 EIE91988.1 - 0.054 13.6 0.1 0.34 11.0 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_4 PF13613.1 EIE91988.1 - 0.089 12.3 0.0 0.75 9.3 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix of DDE superfamily endonuclease GerE PF00196.14 EIE91988.1 - 0.093 12.0 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family HTH_Tnp_Tc3_2 PF01498.13 EIE91992.1 - 6.8e-12 45.2 0.4 1.7e-11 44.0 0.1 1.9 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.1 EIE91992.1 - 9.1e-07 28.3 0.0 6.3e-05 22.4 0.0 3.3 3 0 0 3 3 3 1 Homeodomain-like domain PAX PF00292.13 EIE91992.1 - 1.3e-05 24.9 0.0 2.4e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 'Paired box' domain HTH_28 PF13518.1 EIE91992.1 - 5.8e-05 22.9 0.0 0.0012 18.8 0.0 2.6 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_29 PF13551.1 EIE91992.1 - 0.00025 21.1 0.0 0.0007 19.7 0.0 1.7 1 1 0 1 1 1 1 Winged helix-turn helix HTH_11 PF08279.7 EIE91992.1 - 0.00032 20.2 0.1 0.0098 15.5 0.0 2.5 2 0 0 2 2 2 1 HTH domain HTH_Tnp_ISL3 PF13542.1 EIE91992.1 - 0.0016 17.5 0.0 0.015 14.5 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_7 PF02796.10 EIE91992.1 - 0.004 16.9 0.5 0.13 12.1 0.0 2.8 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase Trp_repressor PF01371.14 EIE91992.1 - 0.0047 16.7 0.1 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 Trp repressor protein HTH_26 PF13443.1 EIE91992.1 - 0.0073 16.4 2.0 0.033 14.3 0.0 2.7 4 0 0 4 4 2 1 Cro/C1-type HTH DNA-binding domain LacI PF00356.16 EIE91992.1 - 0.0097 15.5 0.0 0.65 9.6 0.0 2.5 2 0 0 2 2 2 1 Bacterial regulatory proteins, lacI family CENP-B_N PF04218.8 EIE91992.1 - 0.019 14.4 0.6 0.15 11.4 0.1 2.5 3 0 0 3 3 3 0 CENP-B N-terminal DNA-binding domain DDE_Tnp_ISAZ013 PF07592.6 EIE91992.1 - 0.021 13.5 0.0 0.028 13.1 0.0 1.2 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain HTH_24 PF13412.1 EIE91992.1 - 0.023 14.0 0.1 0.22 10.9 0.0 2.3 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_38 PF13936.1 EIE91992.1 - 0.036 13.6 0.1 0.13 11.8 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_3 PF01381.17 EIE91992.1 - 0.037 13.8 0.1 0.21 11.4 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix GerE PF00196.14 EIE91992.1 - 0.04 13.2 0.3 0.1 11.9 0.1 1.7 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family UPF0258 PF06789.7 EIE91992.1 - 0.043 13.8 0.0 0.062 13.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0258) COX16 PF14138.1 EIE91992.1 - 0.066 13.3 0.0 0.18 11.9 0.0 1.7 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 DDE_3 PF13358.1 EIE91993.1 - 2.9e-07 30.3 0.1 3e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease HGD-D PF06050.8 EIE91993.1 - 0.045 12.5 0.2 0.087 11.6 0.1 1.5 1 1 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component DUF4258 PF14076.1 EIE91993.1 - 0.11 12.4 0.4 2.6 8.1 0.3 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4258) DDE_3 PF13358.1 EIE91995.1 - 6.4e-18 64.9 0.1 1.1e-17 64.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE91995.1 - 3.3e-09 36.6 0.9 1.3e-08 34.7 0.5 2.0 2 0 0 2 2 2 1 Transposase Mod_r PF07200.8 EIE91996.1 - 0.0037 17.2 0.1 0.0071 16.2 0.1 1.4 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Matrilin_ccoil PF10393.4 EIE91996.1 - 0.023 14.0 0.2 0.05 12.9 0.2 1.5 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin Reo_sigmaC PF04582.7 EIE91996.1 - 0.027 13.6 1.0 0.04 13.0 0.7 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DivIC PF04977.10 EIE91996.1 - 0.14 11.6 1.6 0.29 10.6 1.1 1.5 1 0 0 1 1 1 0 Septum formation initiator LacI PF00356.16 EIE91996.1 - 0.21 11.2 3.0 1.2 8.7 0.0 2.8 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family RVT_1 PF00078.22 EIE91997.1 - 6.9e-29 100.7 0.0 1.1e-28 100.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EIE91997.1 - 1.4e-18 66.6 0.0 3.1e-18 65.5 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EIE91997.1 - 5.7e-05 23.1 0.0 0.00017 21.6 0.0 1.8 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family TPR_14 PF13428.1 EIE91998.1 - 3.7e-06 27.0 1.5 0.0067 16.9 0.3 3.4 1 1 2 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 EIE91998.1 - 0.0011 18.9 0.1 0.79 10.0 0.0 3.2 1 1 2 3 3 3 1 Tetratricopeptide repeat MIT PF04212.13 EIE91998.1 - 0.0023 17.7 0.3 1.2 9.0 0.0 2.9 2 1 1 3 3 3 2 MIT (microtubule interacting and transport) domain TPR_11 PF13414.1 EIE91998.1 - 0.0035 16.9 0.0 0.26 10.9 0.0 2.8 2 1 1 3 3 3 2 TPR repeat TPR_19 PF14559.1 EIE91998.1 - 0.0063 16.8 0.2 0.089 13.1 0.1 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 EIE91998.1 - 0.019 15.6 0.6 0.062 14.0 0.2 2.1 2 2 0 2 2 2 0 Tetratricopeptide repeat HEPN PF05168.9 EIE91998.1 - 0.024 14.5 0.3 0.053 13.4 0.2 1.7 1 1 0 1 1 1 0 HEPN domain TPR_2 PF07719.12 EIE91998.1 - 0.1 12.5 0.3 29 4.9 0.0 3.7 4 1 0 4 4 4 0 Tetratricopeptide repeat SIS PF01380.17 EIE92001.1 - 0.014 14.9 0.2 0.017 14.7 0.2 1.2 1 0 0 1 1 1 0 SIS domain DUF3090 PF11290.3 EIE92001.1 - 0.048 13.1 1.0 0.055 12.9 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3090) DDE_3 PF13358.1 EIE92002.1 - 0.00021 21.0 0.1 0.00033 20.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EIE92004.1 - 5.6e-11 42.3 0.7 8.4e-11 41.8 0.5 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE92005.1 - 1.6e-07 31.2 0.7 1.9e-06 27.8 0.0 2.1 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 EIE92005.1 - 4.2e-06 26.8 0.1 1.1e-05 25.5 0.0 1.6 2 0 0 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.1 EIE92005.1 - 0.00019 21.0 0.0 0.00041 19.8 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_IclR PF09339.5 EIE92005.1 - 0.0019 17.7 0.0 0.0034 16.9 0.0 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_17 PF12728.2 EIE92005.1 - 0.0055 16.9 0.0 0.0093 16.1 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_28 PF13518.1 EIE92005.1 - 0.0083 16.1 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.1 EIE92005.1 - 0.032 14.4 0.1 0.066 13.4 0.0 1.5 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain HTH_3 PF01381.17 EIE92005.1 - 0.048 13.5 0.1 0.097 12.5 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix HTH_24 PF13412.1 EIE92005.1 - 0.088 12.2 0.1 0.28 10.5 0.0 1.8 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_21 PF13276.1 EIE92005.1 - 0.16 12.0 0.5 2.4 8.2 0.0 2.3 2 0 0 2 2 2 0 HTH-like domain LacI PF00356.16 EIE92005.1 - 0.33 10.6 2.1 1.3 8.7 0.3 2.6 1 1 0 2 2 2 0 Bacterial regulatory proteins, lacI family HTH_Tnp_Tc3_2 PF01498.13 EIE92007.1 - 7.4e-10 38.7 0.2 8.9e-10 38.4 0.1 1.1 1 0 0 1 1 1 1 Transposase DDE_Tnp_ISAZ013 PF07592.6 EIE92007.1 - 0.016 14.0 0.1 0.016 14.0 0.0 1.0 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain DDE_3 PF13358.1 EIE92008.1 - 7.4e-15 54.9 0.0 1.3e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE92008.1 - 7.9e-14 51.4 0.3 2.4e-13 49.9 0.2 1.9 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.1 EIE92008.1 - 3.4e-05 23.9 0.4 7e-05 22.9 0.3 1.6 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EIE92008.1 - 0.00022 20.7 0.2 0.0025 17.4 0.0 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_7 PF02796.10 EIE92008.1 - 0.00048 19.9 0.4 0.068 13.0 0.1 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase rve PF00665.21 EIE92008.1 - 0.041 13.9 0.0 0.21 11.7 0.0 2.2 1 1 1 2 2 2 0 Integrase core domain PAX PF00292.13 EIE92010.1 - 0.00038 20.1 0.0 0.00063 19.4 0.0 1.4 1 0 0 1 1 1 1 'Paired box' domain HTH_23 PF13384.1 EIE92010.1 - 0.00073 19.1 0.0 0.0047 16.5 0.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.1 EIE92010.1 - 0.0071 16.3 0.0 0.018 15.0 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.13 EIE92010.1 - 0.0083 16.1 0.8 0.014 15.3 0.1 1.8 2 0 0 2 2 2 1 Transposase Trp_repressor PF01371.14 EIE92010.1 - 0.013 15.4 0.0 0.037 13.9 0.0 1.7 2 0 0 2 2 2 0 Trp repressor protein DDE_3 PF13358.1 EIE92010.1 - 0.099 12.3 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease HTH_26 PF13443.1 EIE92010.1 - 0.13 12.4 0.2 0.33 11.2 0.0 1.7 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain HTH_38 PF13936.1 EIE92012.1 - 0.00016 21.1 0.1 0.00031 20.2 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain MarR PF01047.17 EIE92012.1 - 0.00093 18.8 0.1 0.047 13.4 0.0 2.3 2 0 0 2 2 2 1 MarR family HTH_23 PF13384.1 EIE92012.1 - 0.0026 17.3 0.9 0.0045 16.6 0.0 1.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.1 EIE92012.1 - 0.0034 17.4 0.2 0.0048 17.0 0.2 1.2 1 0 0 1 1 1 1 Winged helix-turn helix Sigma54_DBD PF04552.8 EIE92012.1 - 0.0093 15.4 0.5 0.018 14.5 0.4 1.7 1 1 0 1 1 1 1 Sigma-54, DNA binding domain TrmB PF01978.14 EIE92012.1 - 0.021 14.5 0.8 0.23 11.2 0.0 2.1 1 1 1 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_Crp_2 PF13545.1 EIE92012.1 - 0.024 14.4 0.2 0.49 10.2 0.0 2.1 1 1 1 2 2 2 0 Crp-like helix-turn-helix domain Fe_dep_repress PF01325.14 EIE92012.1 - 0.029 14.3 0.0 0.082 12.8 0.0 1.7 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain MarR_2 PF12802.2 EIE92012.1 - 0.032 13.8 0.3 1.3 8.7 0.0 2.2 2 0 0 2 2 2 0 MarR family Phage_CII PF05269.6 EIE92012.1 - 0.037 14.0 0.2 0.13 12.3 0.0 2.0 1 1 0 2 2 2 0 Bacteriophage CII protein LacI PF00356.16 EIE92012.1 - 0.039 13.5 0.4 0.12 12.0 0.3 2.0 1 1 0 1 1 1 0 Bacterial regulatory proteins, lacI family NPIP PF06409.6 EIE92012.1 - 0.045 12.4 0.2 0.053 12.2 0.1 1.1 1 0 0 1 1 1 0 Nuclear pore complex interacting protein (NPIP) P63C PF10546.4 EIE92012.1 - 0.048 13.6 0.0 0.076 12.9 0.0 1.3 1 0 0 1 1 1 0 P63C domain HTH_28 PF13518.1 EIE92012.1 - 0.057 13.4 0.0 0.17 11.8 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_4 PF13613.1 EIE92012.1 - 0.079 12.5 0.1 0.15 11.6 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease TetR_N PF00440.18 EIE92012.1 - 0.083 12.5 0.1 0.17 11.5 0.1 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family Sigma70_r4_2 PF08281.7 EIE92012.1 - 0.12 11.8 0.1 0.22 11.0 0.1 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_5 PF01022.15 EIE92012.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_3 PF01381.17 EIE92012.1 - 0.13 12.1 0.1 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix HTH_Tnp_Tc3_2 PF01498.13 EIE92012.1 - 0.52 10.3 4.0 1.9 8.6 0.5 2.3 1 1 1 2 2 2 0 Transposase DDE_3 PF13358.1 EIE92013.1 - 1.3e-17 63.8 0.0 3.4e-17 62.5 0.0 1.7 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE92013.1 - 4e-09 36.4 0.7 1.7e-08 34.3 0.7 2.0 2 1 0 2 2 2 1 Transposase DDE_3 PF13358.1 EIE92014.1 - 2.9e-11 43.3 0.0 4.6e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE92014.1 - 1.3e-07 31.5 0.4 2.7e-07 30.5 0.3 1.5 1 0 0 1 1 1 1 Transposase HTH_Tnp_Tc3_2 PF01498.13 EIE92015.1 - 5.3e-06 26.4 1.1 1.3e-05 25.1 0.2 2.0 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.1 EIE92016.1 - 7.4e-15 54.9 0.0 1.3e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE92016.1 - 8e-14 51.4 0.3 2.4e-13 49.9 0.2 1.9 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.1 EIE92016.1 - 3.4e-05 23.9 0.4 7e-05 22.9 0.3 1.6 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EIE92016.1 - 0.00022 20.7 0.2 0.0025 17.4 0.0 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_7 PF02796.10 EIE92016.1 - 0.00048 19.9 0.4 0.068 13.0 0.1 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase rve PF00665.21 EIE92016.1 - 0.041 13.9 0.0 0.21 11.7 0.0 2.2 1 1 1 2 2 2 0 Integrase core domain DDE_3 PF13358.1 EIE92018.1 - 2.5e-21 75.9 0.2 4.8e-21 75.0 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE92018.1 - 3.9e-15 55.6 0.3 1e-14 54.3 0.2 1.8 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.1 EIE92018.1 - 8.1e-06 26.5 0.1 0.00063 20.4 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_33 PF13592.1 EIE92018.1 - 8.3e-05 22.0 0.1 0.00037 19.9 0.0 2.2 2 0 0 2 2 2 1 Winged helix-turn helix HTH_21 PF13276.1 EIE92018.1 - 0.0042 17.0 0.0 0.17 11.8 0.0 2.8 2 1 0 2 2 2 1 HTH-like domain DDE_Tnp_IS66 PF03050.9 EIE92018.1 - 0.011 14.9 0.8 1.6 7.8 0.0 3.0 2 1 0 2 2 2 0 Transposase IS66 family HTH_29 PF13551.1 EIE92018.1 - 0.012 15.7 0.0 0.045 13.9 0.0 2.0 1 0 0 1 1 1 0 Winged helix-turn helix rve PF00665.21 EIE92018.1 - 0.015 15.3 0.0 0.14 12.2 0.0 2.6 2 1 0 2 2 2 0 Integrase core domain HMG_box_2 PF09011.5 EIE92018.1 - 0.058 13.7 0.5 0.058 13.7 0.3 2.2 2 0 0 2 2 2 0 HMG-box domain TSC22 PF01166.13 EIE92019.1 - 0.00039 20.3 2.6 0.00066 19.5 1.8 1.3 1 0 0 1 1 1 1 TSC-22/dip/bun family DUF972 PF06156.8 EIE92019.1 - 0.0023 18.2 0.2 0.0037 17.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF972) Lebercilin PF15619.1 EIE92019.1 - 0.019 14.4 4.5 0.027 13.8 3.1 1.2 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease ATG16 PF08614.6 EIE92019.1 - 0.036 13.8 2.7 0.056 13.2 1.9 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF904 PF06005.7 EIE92019.1 - 0.15 12.3 4.1 0.29 11.4 2.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DivIC PF04977.10 EIE92019.1 - 0.51 9.8 4.5 0.84 9.1 3.1 1.4 1 0 0 1 1 1 0 Septum formation initiator PC4 PF02229.11 EIE92022.1 - 0.11 11.6 0.0 0.22 10.7 0.0 1.5 1 0 0 1 1 1 0 Transcriptional Coactivator p15 (PC4) SIS PF01380.17 EIE92023.1 - 0.014 14.9 0.2 0.017 14.7 0.2 1.2 1 0 0 1 1 1 0 SIS domain DUF3090 PF11290.3 EIE92023.1 - 0.048 13.1 1.0 0.055 12.9 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3090) Lzipper-MIP1 PF14389.1 EIE92024.1 - 0.0049 16.9 0.4 0.013 15.5 0.3 1.7 1 0 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 ChaB PF06150.7 EIE92024.1 - 0.069 12.9 0.6 0.25 11.1 0.1 2.2 2 0 0 2 2 2 0 ChaB IncA PF04156.9 EIE92024.1 - 0.17 11.5 1.2 0.28 10.7 0.9 1.4 1 0 0 1 1 1 0 IncA protein DUF4404 PF14357.1 EIE92024.1 - 0.21 11.9 1.9 5.7 7.4 0.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) SRR PF07709.6 EIE92024.1 - 0.23 11.7 4.4 5.5 7.6 0.0 3.5 3 0 0 3 3 3 0 Seven Residue Repeat DUF4218 PF13960.1 EIE92025.1 - 1.4e-05 24.5 0.1 2.6e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) DDE_3 PF13358.1 EIE92026.1 - 6.8e-21 74.5 1.0 8.3e-21 74.2 0.3 1.4 2 0 0 2 2 2 1 DDE superfamily endonuclease Transposase_21 PF02992.9 EIE92028.1 - 3.6e-18 65.4 1.1 7e-18 64.5 0.1 1.8 2 0 0 2 2 2 1 Transposase family tnp2 DUF1508 PF07411.7 EIE92028.1 - 1.8 8.0 5.5 0.87 9.0 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1508) Transposase_21 PF02992.9 EIE92029.1 - 8.8e-16 57.6 0.0 1.4e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 EIE92030.1 - 0.067 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) LysR_substrate PF03466.15 EIE92030.1 - 0.11 11.5 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 LysR substrate binding domain DDE_3 PF13358.1 EIE92031.1 - 6e-18 64.9 0.1 1.4e-17 63.7 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE92031.1 - 5.4e-12 45.5 1.0 5.4e-12 45.5 0.7 2.2 3 0 0 3 3 3 1 Transposase HTH_29 PF13551.1 EIE92031.1 - 0.0002 21.4 0.7 0.0004 20.5 0.1 1.8 2 0 0 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.1 EIE92031.1 - 0.00094 18.7 0.1 0.0025 17.3 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_7 PF02796.10 EIE92031.1 - 0.0074 16.1 0.0 0.021 14.6 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_30 PF13556.1 EIE92031.1 - 0.021 14.3 0.0 0.17 11.4 0.0 2.1 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain HTH_38 PF13936.1 EIE92031.1 - 0.031 13.8 0.0 0.11 12.0 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain RecX PF02631.11 EIE92031.1 - 0.13 12.4 0.3 0.27 11.4 0.2 1.5 1 0 0 1 1 1 0 RecX family LAG1-DNAbind PF09271.6 EIE92032.1 - 0.045 14.2 0.9 0.045 14.2 0.6 1.7 2 0 0 2 2 2 0 LAG1, DNA binding TSA PF03249.8 EIE92032.1 - 0.053 12.0 4.0 0.071 11.6 2.7 1.2 1 0 0 1 1 1 0 Type specific antigen YebO PF13974.1 EIE92032.1 - 0.079 12.7 10.9 0.81 9.5 0.0 2.4 2 0 0 2 2 2 0 YebO-like protein FKBP_N PF01346.13 EIE92032.1 - 0.25 11.3 8.2 0.097 12.7 3.2 2.1 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase ATP-synt_E PF05680.7 EIE92032.1 - 0.34 10.9 4.3 2.4 8.1 1.9 2.3 2 0 0 2 2 2 0 ATP synthase E chain DUF2140 PF09911.4 EIE92032.1 - 0.34 10.0 2.1 0.59 9.2 1.5 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) rve PF00665.21 EIE92033.1 - 1.9e-22 79.6 0.0 4.7e-22 78.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE92033.1 - 1.5e-15 57.1 0.1 2.9e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.12 EIE92033.1 - 8.5e-09 35.3 0.1 2.4e-08 33.9 0.1 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein Chromo PF00385.19 EIE92033.1 - 4.4e-08 32.6 0.1 1e-07 31.5 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.1 EIE92033.1 - 5.3e-05 23.6 0.0 0.00012 22.4 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.5 EIE92033.1 - 0.00044 19.5 1.6 0.0015 17.8 1.1 2.0 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Asp_protease PF09668.5 EIE92033.1 - 0.0085 15.6 0.0 0.019 14.5 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EIE92033.1 - 0.023 14.4 0.0 0.058 13.2 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease UBN2 PF14223.1 EIE92033.1 - 0.14 11.9 0.0 0.37 10.5 0.0 1.8 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type RVT_1 PF00078.22 EIE92035.1 - 5.3e-14 52.0 0.2 1.7e-13 50.4 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.12 EIE92035.1 - 2.5e-06 27.4 3.4 3e-06 27.1 0.1 2.6 2 0 0 2 2 2 1 Retrotransposon gag protein DDE_3 PF13358.1 EIE92036.1 - 4.4e-11 42.7 0.2 5.8e-11 42.3 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease FAM222A PF15258.1 EIE92037.1 - 0.008 15.4 6.4 0.011 14.9 4.4 1.2 1 0 0 1 1 1 1 Protein family of FAM222A Med15 PF09606.5 EIE92037.1 - 0.018 13.2 12.5 0.024 12.8 8.7 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Transposase_21 PF02992.9 EIE92038.1 - 1.4e-21 76.6 0.3 4.5e-21 74.9 0.0 1.9 2 0 0 2 2 2 1 Transposase family tnp2 DUF1258 PF06869.7 EIE92038.1 - 0.0053 15.8 0.0 0.011 14.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) DDE_3 PF13358.1 EIE92040.1 - 1.2e-12 47.7 0.1 1.5e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Nebulin PF00880.13 EIE92040.1 - 0.033 13.7 0.5 0.094 12.3 0.1 1.9 2 0 0 2 2 2 0 Nebulin repeat rve PF00665.21 EIE92041.1 - 2.5e-20 72.7 0.0 8e-20 71.1 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 EIE92041.1 - 2e-10 40.1 0.4 5.3e-10 38.8 0.3 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVT_1 PF00078.22 EIE92041.1 - 1.7e-06 27.5 0.1 3.9e-06 26.3 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HLH PF00010.21 EIE92042.1 - 1.3e-11 44.0 2.9 1.3e-11 44.0 2.0 3.0 1 1 2 3 3 3 1 Helix-loop-helix DNA-binding domain DUF1090 PF06476.7 EIE92042.1 - 0.022 14.4 0.4 0.022 14.4 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1090) POP1 PF06978.6 EIE92042.1 - 0.038 13.6 5.0 0.059 13.0 3.5 1.2 1 0 0 1 1 1 0 Ribonucleases P/MRP protein subunit POP1 SRRM_C PF15230.1 EIE92042.1 - 4.2 7.5 12.3 2.1 8.5 6.3 2.0 2 0 0 2 2 2 0 Serine/arginine repetitive matrix protein C-terminus Ribosomal_S9 PF00380.14 EIE92043.1 - 3.8e-33 114.3 0.1 4.6e-33 114.0 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Cupin_8 PF13621.1 EIE92044.1 - 0.067 12.6 4.2 0.027 13.9 0.7 1.7 1 1 1 2 2 2 0 Cupin-like domain DUF106 PF01956.11 EIE92044.1 - 1.3 8.5 8.6 0.73 9.3 4.6 1.7 1 1 0 1 1 1 0 Integral membrane protein DUF106 UQ_con PF00179.21 EIE92045.1 - 8.9e-38 128.8 0.3 1e-37 128.6 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EIE92045.1 - 2.6e-05 24.0 0.0 3.1e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EIE92045.1 - 0.00026 20.8 0.0 0.00031 20.5 0.0 1.1 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 EIE92045.1 - 0.011 15.3 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 0 UEV domain Arylesterase PF01731.15 EIE92046.1 - 2.1e-07 30.8 0.3 5.5e-07 29.4 0.0 1.8 2 0 0 2 2 2 1 Arylesterase MFS_1 PF07690.11 EIE92047.1 - 2.3e-17 62.7 58.4 1.5e-15 56.7 40.3 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EIE92047.1 - 4.3e-05 21.9 29.4 6.2e-05 21.3 20.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3317 PF11779.3 EIE92050.1 - 5e-17 61.0 4.3 5.3e-17 61.0 3.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) Ribosomal_S19 PF00203.16 EIE92051.1 - 2.6e-34 116.6 0.2 3.6e-34 116.2 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 FliH PF02108.11 EIE92051.1 - 0.1 12.4 0.0 0.13 12.1 0.0 1.1 1 0 0 1 1 1 0 Flagellar assembly protein FliH Voldacs PF03517.8 EIE92052.1 - 5.3e-26 91.0 0.5 6.9e-26 90.6 0.3 1.1 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling GRAM PF02893.15 EIE92052.1 - 0.0033 16.9 0.0 0.0057 16.1 0.0 1.3 1 0 0 1 1 1 1 GRAM domain Fork_head PF00250.13 EIE92053.1 - 4.6e-36 122.7 0.7 1.1e-35 121.5 0.4 1.8 2 0 0 2 2 2 1 Fork head domain PhyH PF05721.8 EIE92054.1 - 3.4e-35 122.0 0.0 4.6e-35 121.5 0.0 1.2 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Metallophos PF00149.23 EIE92057.1 - 1.7e-09 37.3 2.3 2.4e-09 36.9 1.6 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase His_binding PF02098.11 EIE92057.1 - 0.097 12.4 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Tick histamine binding protein dUTPase PF00692.14 EIE92058.1 - 1.4e-40 137.7 0.0 1.6e-40 137.5 0.0 1.0 1 0 0 1 1 1 1 dUTPase Sas10_Utp3 PF04000.10 EIE92059.1 - 8.5e-13 48.3 1.4 1.1e-12 47.9 1.0 1.1 1 0 0 1 1 1 1 Sas10/Utp3/C1D family RVT_1 PF00078.22 EIE92063.1 - 9.9e-29 100.2 2.6 1.3e-20 73.6 0.1 3.3 2 1 1 3 3 3 3 Reverse transcriptase (RNA-dependent DNA polymerase) FlgN PF05130.7 EIE92065.1 - 1.9 8.7 6.7 6.3 7.0 0.4 2.5 2 0 0 2 2 2 0 FlgN protein RVT_1 PF00078.22 EIE92066.1 - 1.8e-25 89.5 0.0 3.8e-25 88.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_3 PF13358.1 EIE92067.1 - 1.4e-07 31.3 0.0 2.4e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease RVT_1 PF00078.22 EIE92068.1 - 1.5e-19 70.2 0.0 3.9e-19 68.8 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EIE92068.1 - 1.4e-17 63.3 2.3 3.4e-17 62.1 1.2 2.1 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EIE92068.1 - 1.3e-07 31.7 0.1 2.6e-07 30.8 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Lar_restr_allev PF14354.1 EIE92068.1 - 0.017 15.4 1.5 0.038 14.2 0.4 2.1 2 0 0 2 2 2 0 Restriction alleviation protein Lar Zn_Tnp_IS1595 PF12760.2 EIE92068.1 - 0.17 11.6 2.4 0.58 9.9 1.6 2.0 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.5 EIE92068.1 - 0.51 10.3 2.4 22 5.0 0.1 2.7 2 0 0 2 2 2 0 Zinc ribbon domain DDE_3 PF13358.1 EIE92069.1 - 2e-29 102.1 0.0 4.6e-29 101.0 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 EIE92069.1 - 6.1e-10 39.2 0.1 2.4e-09 37.3 0.0 1.9 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.1 EIE92069.1 - 7.5e-08 33.0 0.3 1.9e-07 31.7 0.0 1.9 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.1 EIE92069.1 - 2.7e-06 27.2 2.9 1.1e-05 25.3 0.1 2.9 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_23 PF13384.1 EIE92069.1 - 4.4e-05 22.9 2.4 0.00038 20.0 0.0 2.9 3 0 0 3 3 3 1 Homeodomain-like domain rve PF00665.21 EIE92069.1 - 0.0015 18.6 0.0 0.0048 16.9 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain HTH_17 PF12728.2 EIE92069.1 - 0.0056 16.8 0.2 0.99 9.7 0.1 2.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_1 PF01527.15 EIE92069.1 - 0.0066 16.3 2.5 0.0078 16.1 0.3 2.0 2 0 0 2 2 2 1 Transposase DDE_1 PF03184.14 EIE92069.1 - 0.017 14.2 0.0 0.39 9.8 0.0 2.3 2 0 0 2 2 2 0 DDE superfamily endonuclease HTH_Tnp_ISL3 PF13542.1 EIE92069.1 - 0.036 13.2 0.1 0.074 12.2 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 DUF2264 PF10022.4 EIE92070.1 - 0.0032 16.1 0.0 0.0044 15.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) TFCD_C PF12612.3 EIE92070.1 - 0.0043 16.4 0.1 0.0073 15.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin folding cofactor D C terminal DDE_3 PF13358.1 EIE92071.1 - 2e-29 102.1 0.0 4.6e-29 101.0 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 EIE92071.1 - 6.1e-10 39.2 0.1 2.4e-09 37.3 0.0 1.9 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.1 EIE92071.1 - 7.5e-08 33.0 0.3 1.9e-07 31.7 0.0 1.9 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.1 EIE92071.1 - 2.7e-06 27.2 2.9 1.1e-05 25.3 0.1 2.9 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_23 PF13384.1 EIE92071.1 - 4.4e-05 22.9 2.4 0.00038 20.0 0.0 2.9 3 0 0 3 3 3 1 Homeodomain-like domain rve PF00665.21 EIE92071.1 - 0.0015 18.6 0.0 0.0048 16.9 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain HTH_17 PF12728.2 EIE92071.1 - 0.0056 16.8 0.2 0.99 9.7 0.1 2.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_1 PF01527.15 EIE92071.1 - 0.0066 16.3 2.5 0.0078 16.1 0.3 2.0 2 0 0 2 2 2 1 Transposase DDE_1 PF03184.14 EIE92071.1 - 0.017 14.2 0.0 0.39 9.8 0.0 2.3 2 0 0 2 2 2 0 DDE superfamily endonuclease HTH_Tnp_ISL3 PF13542.1 EIE92071.1 - 0.036 13.2 0.1 0.074 12.2 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Glyco_hydro_43 PF04616.9 EIE92072.1 - 1.5e-46 158.7 4.4 1.9e-46 158.4 3.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_68 PF02435.11 EIE92072.1 - 0.0026 16.5 0.1 0.01 14.5 0.0 1.8 1 1 0 1 1 1 1 Levansucrase/Invertase Glyco_hydro_43 PF04616.9 EIE92073.1 - 1.5e-46 158.7 4.4 1.9e-46 158.4 3.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_68 PF02435.11 EIE92073.1 - 0.0026 16.5 0.1 0.01 14.5 0.0 1.8 1 1 0 1 1 1 1 Levansucrase/Invertase VTC PF09359.5 EIE92075.1 - 3.1e-105 351.2 0.2 5.4e-105 350.4 0.1 1.4 1 0 0 1 1 1 1 VTC domain CPSase_L_D2 PF02786.12 EIE92075.1 - 3.1e-75 252.0 0.0 6e-75 251.1 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 EIE92075.1 - 4.9e-29 100.4 0.0 2.2e-28 98.3 0.0 2.2 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 EIE92075.1 - 1.6e-27 95.7 0.0 4.8e-27 94.2 0.0 1.9 2 0 0 2 2 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain SPX PF03105.14 EIE92075.1 - 2.8e-17 63.4 12.6 5.4e-07 29.6 0.1 4.3 2 1 1 3 3 3 2 SPX domain ATP-grasp_4 PF13535.1 EIE92075.1 - 2.7e-14 53.3 0.0 9.3e-14 51.5 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain DUF202 PF02656.10 EIE92075.1 - 1.1e-11 44.8 0.9 1.1e-11 44.8 0.6 1.7 2 0 0 2 2 1 1 Domain of unknown function (DUF202) Biotin_lipoyl PF00364.17 EIE92075.1 - 1.3e-10 40.7 0.5 3.1e-10 39.5 0.3 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.8 EIE92075.1 - 2e-10 40.4 0.0 4.6e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 EIE92075.1 - 2e-08 33.4 0.0 3.8e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EIE92075.1 - 2.5e-06 26.9 0.0 5.2e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 EIE92075.1 - 0.0003 20.3 0.0 0.00065 19.2 0.0 1.5 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 EIE92075.1 - 0.0022 17.9 0.1 0.0043 16.9 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 EIE92075.1 - 0.014 15.0 0.0 0.036 13.7 0.0 1.7 1 0 0 1 1 1 0 Biotin-lipoyl like Ion_trans PF00520.26 EIE92076.1 - 2.8e-94 313.9 69.3 8e-34 116.6 6.0 5.2 5 0 0 5 5 5 4 Ion transport protein PHZA_PHZB PF03284.8 EIE92076.1 - 0.12 11.4 0.0 0.23 10.5 0.0 1.4 1 0 0 1 1 1 0 Phenazine biosynthesis protein A/B LRR_4 PF12799.2 EIE92077.1 - 1.5e-17 62.8 32.5 1.3e-07 31.1 5.9 5.2 3 2 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EIE92077.1 - 2.3e-17 62.4 24.5 1.5e-10 40.6 9.7 4.1 3 1 1 4 4 4 4 Leucine rich repeat LRR_1 PF00560.28 EIE92077.1 - 1.1e-14 52.1 27.2 0.0078 16.0 0.3 7.4 7 0 0 7 7 7 4 Leucine Rich Repeat LRR_7 PF13504.1 EIE92077.1 - 2.1e-10 39.0 22.7 0.082 13.1 0.1 7.2 7 0 0 7 7 7 4 Leucine rich repeat LRR_6 PF13516.1 EIE92077.1 - 4.9e-07 29.1 25.5 0.24 11.5 0.3 6.2 6 0 0 6 6 6 4 Leucine Rich repeat LRR_5 PF13306.1 EIE92077.1 - 0.00048 19.8 0.5 0.00096 18.8 0.4 1.5 1 0 0 1 1 1 1 Leucine rich repeats (6 copies) LRR_9 PF14580.1 EIE92077.1 - 0.0073 15.8 3.6 0.013 15.0 1.6 1.9 1 1 1 2 2 2 1 Leucine-rich repeat DUF2256 PF10013.4 EIE92077.1 - 0.25 11.1 2.8 1.7 8.4 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-FCS PF06467.9 EIE92077.1 - 1.1 8.9 9.3 17 5.1 6.4 2.3 1 1 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif Pro_dh PF01619.13 EIE92078.1 - 5.8e-57 193.0 2.2 9.3e-57 192.3 1.5 1.2 1 0 0 1 1 1 1 Proline dehydrogenase XS PF03468.9 EIE92078.1 - 0.023 14.6 0.0 0.053 13.4 0.0 1.5 1 0 0 1 1 1 0 XS domain PPR_3 PF13812.1 EIE92078.1 - 0.045 14.0 0.0 0.19 12.0 0.0 2.2 1 0 0 1 1 1 0 Pentatricopeptide repeat domain Uds1 PF15456.1 EIE92079.1 - 0.058 13.3 1.9 0.06 13.3 1.3 1.1 1 0 0 1 1 1 0 Up-regulated During Septation TpcC PF12642.2 EIE92079.1 - 0.063 12.8 1.8 0.067 12.7 1.2 1.0 1 0 0 1 1 1 0 Conjugative transposon protein TcpC IncA PF04156.9 EIE92079.1 - 0.4 10.2 2.4 0.42 10.1 1.6 1.0 1 0 0 1 1 1 0 IncA protein NTP_transferase PF00483.18 EIE92080.1 - 4.3e-28 98.2 0.0 6.6e-28 97.6 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 EIE92080.1 - 2.3e-08 34.2 0.0 6.3e-08 32.8 0.0 1.8 1 1 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.19 EIE92080.1 - 0.024 14.1 0.4 4.5 6.9 0.0 3.1 2 1 0 2 2 2 0 Bacterial transferase hexapeptide (six repeats) IspD PF01128.14 EIE92080.1 - 0.056 12.9 0.0 0.15 11.5 0.0 1.7 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GPS PF01825.16 EIE92080.1 - 0.15 12.1 0.3 0.35 11.0 0.0 1.7 2 0 0 2 2 2 0 Latrophilin/CL-1-like GPS domain HAD PF12710.2 EIE92081.1 - 7.9e-21 75.0 0.4 2e-20 73.8 0.3 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EIE92081.1 - 7.9e-19 67.6 0.1 1.4e-18 66.7 0.1 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EIE92081.1 - 2.4e-16 60.8 0.7 2.5e-15 57.5 0.5 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EIE92081.1 - 1.6e-11 43.9 0.0 6.1e-11 42.1 0.0 1.9 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EIE92081.1 - 0.00033 20.3 0.0 0.0031 17.1 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EIE92081.1 - 0.041 14.1 0.0 0.081 13.1 0.0 1.5 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DUF3613 PF12266.3 EIE92081.1 - 0.088 12.3 0.1 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3613) HTH_Tnp_Tc3_2 PF01498.13 EIE92085.1 - 3.3e-06 27.0 2.1 4.7e-06 26.5 0.3 2.0 2 1 0 2 2 2 1 Transposase HTH_Tnp_4 PF13613.1 EIE92085.1 - 0.0005 19.5 0.0 0.00098 18.6 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease HTH_23 PF13384.1 EIE92085.1 - 0.0029 17.2 0.0 0.0074 15.9 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_30 PF13556.1 EIE92085.1 - 0.049 13.2 0.0 0.12 12.0 0.0 1.6 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain RecX PF02631.11 EIE92085.1 - 0.095 12.9 0.2 0.14 12.3 0.1 1.3 1 0 0 1 1 1 0 RecX family Exo_endo_phos_2 PF14529.1 EIE92086.1 - 1.8e-15 56.5 0.1 4.5e-15 55.3 0.1 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EIE92086.1 - 1.3e-06 28.5 1.1 2.6e-06 27.5 0.0 2.0 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family HTH_Tnp_Tc3_2 PF01498.13 EIE92087.1 - 3.3e-06 27.0 2.1 4.7e-06 26.5 0.3 2.0 2 1 0 2 2 2 1 Transposase HTH_Tnp_4 PF13613.1 EIE92087.1 - 0.0005 19.5 0.0 0.00098 18.6 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease HTH_23 PF13384.1 EIE92087.1 - 0.0029 17.2 0.0 0.0074 15.9 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_30 PF13556.1 EIE92087.1 - 0.049 13.2 0.0 0.12 12.0 0.0 1.6 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain RecX PF02631.11 EIE92087.1 - 0.095 12.9 0.2 0.14 12.3 0.1 1.3 1 0 0 1 1 1 0 RecX family SYCE1 PF15233.1 EIE92088.1 - 0.0073 16.2 0.3 0.012 15.5 0.2 1.2 1 0 0 1 1 1 1 Synaptonemal complex central element protein 1 DUF972 PF06156.8 EIE92088.1 - 0.034 14.4 0.2 0.057 13.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF3450 PF11932.3 EIE92088.1 - 0.045 13.0 0.4 0.068 12.4 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) TBPIP PF07106.8 EIE92088.1 - 0.061 12.8 0.1 0.099 12.1 0.0 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Cluap1 PF10234.4 EIE92088.1 - 0.064 12.4 0.1 0.088 11.9 0.0 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 DUF177 PF02620.12 EIE92088.1 - 0.13 12.3 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized ACR, COG1399 RVT_1 PF00078.22 EIE92089.1 - 1.6e-27 96.2 0.0 2.5e-27 95.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EIE92089.1 - 1.9e-14 53.2 0.0 4.9e-14 51.9 0.0 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EIE92089.1 - 7.5e-06 26.0 0.0 2.4e-05 24.3 0.0 1.9 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family FlxA PF14282.1 EIE92089.1 - 0.44 10.5 2.7 0.81 9.6 1.8 1.4 1 0 0 1 1 1 0 FlxA-like protein Serglycin PF04360.7 EIE92089.1 - 1 9.0 11.3 0.013 15.2 2.3 2.0 2 0 0 2 2 2 0 Serglycin DDE_Tnp_IS1595 PF12762.2 EIE92091.1 - 2.5e-07 30.6 0.1 4.6e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 ISXO2-like transposase domain DDE_3 PF13358.1 EIE92093.1 - 0.0021 17.8 0.1 0.0046 16.7 0.1 1.9 1 1 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EIE92096.1 - 1.9e-20 73.0 0.0 4.5e-20 71.8 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE92096.1 - 1e-15 57.4 1.7 2.8e-15 56.1 0.3 2.3 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 EIE92096.1 - 3.2e-06 27.2 0.2 8.6e-06 25.8 0.2 1.7 1 0 0 1 1 1 1 Winged helix-turn helix HTH_38 PF13936.1 EIE92096.1 - 1.2e-05 24.7 0.1 3.3e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_32 PF13565.1 EIE92096.1 - 3.8e-05 24.3 1.5 0.02 15.6 0.1 3.7 4 0 0 4 4 3 1 Homeodomain-like domain HTH_23 PF13384.1 EIE92096.1 - 7.9e-05 22.1 0.1 0.0028 17.2 0.0 2.7 2 0 0 2 2 2 1 Homeodomain-like domain Sigma70_r4_2 PF08281.7 EIE92096.1 - 0.00055 19.3 0.6 0.024 14.0 0.0 3.2 4 0 0 4 4 4 1 Sigma-70, region 4 HTH_28 PF13518.1 EIE92096.1 - 0.0013 18.6 0.0 0.0056 16.6 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_21 PF13276.1 EIE92096.1 - 0.0014 18.5 0.1 0.13 12.2 0.0 2.8 3 0 0 3 3 3 1 HTH-like domain HTH_7 PF02796.10 EIE92096.1 - 0.0022 17.8 1.1 0.1 12.4 0.0 2.8 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase LacI PF00356.16 EIE92096.1 - 0.017 14.7 2.5 2.8 7.6 0.2 3.0 3 0 0 3 3 3 0 Bacterial regulatory proteins, lacI family rve PF00665.21 EIE92096.1 - 0.019 15.0 0.0 0.058 13.5 0.0 1.9 2 0 0 2 2 2 0 Integrase core domain HTH_Tnp_4 PF13613.1 EIE92096.1 - 0.021 14.3 0.1 0.057 12.9 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease CPSase_L_D3 PF02787.14 EIE92096.1 - 0.058 13.1 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain HTH_36 PF13730.1 EIE92096.1 - 0.076 13.1 0.4 4.1 7.6 0.0 2.9 3 0 0 3 3 2 0 Helix-turn-helix domain Sigma70_r4 PF04545.11 EIE92096.1 - 0.1 11.9 0.2 0.79 9.0 0.0 2.5 4 0 0 4 4 4 0 Sigma-70, region 4 HTH_Tnp_ISL3 PF13542.1 EIE92096.1 - 0.15 11.2 2.5 8.4 5.6 0.0 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 HTH_17 PF12728.2 EIE92096.1 - 0.23 11.7 2.8 15 5.9 0.1 3.2 3 0 0 3 3 3 0 Helix-turn-helix domain DDE_3 PF13358.1 EIE92098.1 - 3.5e-12 46.2 0.2 4.7e-12 45.8 0.2 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1700 PF08006.6 EIE92100.1 - 0.0053 16.0 0.7 0.0053 16.0 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1700) DUF3844 PF12955.2 EIE92100.1 - 0.13 12.3 0.7 0.17 11.9 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3844) DUF912 PF06024.7 EIE92100.1 - 0.5 10.4 2.6 0.73 9.9 1.8 1.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Shisa PF13908.1 EIE92100.1 - 0.71 10.0 3.9 0.79 9.8 2.7 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator IncA PF04156.9 EIE92103.1 - 0.66 9.5 6.5 0.72 9.4 4.5 1.0 1 0 0 1 1 1 0 IncA protein Shisa PF13908.1 EIE92103.1 - 1 9.5 11.5 1.4 9.0 8.0 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Amnionless PF14828.1 EIE92103.1 - 2.8 6.3 7.5 2.9 6.2 5.2 1.1 1 0 0 1 1 1 0 Amnionless SUR7 PF06687.7 EIE92103.1 - 7.2 6.1 9.7 8.3 5.9 6.7 1.2 1 0 0 1 1 1 0 SUR7/PalI family DUF2722 PF10846.3 EIE92106.1 - 0.17 10.9 0.1 0.2 10.6 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Exo_endo_phos_2 PF14529.1 EIE92107.1 - 5.8e-14 51.7 0.1 1.6e-13 50.3 0.1 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EIE92107.1 - 0.00093 19.1 0.1 0.0027 17.6 0.0 1.8 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RVT_1 PF00078.22 EIE92107.1 - 0.029 13.7 0.0 0.052 12.8 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Serglycin PF04360.7 EIE92107.1 - 0.085 12.5 2.6 0.19 11.4 1.8 1.5 1 0 0 1 1 1 0 Serglycin RVT_1 PF00078.22 EIE92108.1 - 0.0038 16.6 0.0 0.0041 16.5 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HTH_Tnp_Tc3_2 PF01498.13 EIE92109.1 - 1.6e-05 24.8 1.2 2.3e-05 24.3 0.3 1.7 2 0 0 2 2 2 1 Transposase DDE_Tnp_IS1595 PF12762.2 EIE92110.1 - 2.7e-06 27.3 0.1 4.8e-06 26.4 0.1 1.4 1 0 0 1 1 1 1 ISXO2-like transposase domain DDE_3 PF13358.1 EIE92111.1 - 8.2e-17 61.3 0.1 1.2e-16 60.7 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE92111.1 - 0.0021 18.1 0.0 0.0033 17.5 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain zf-trcl PF13451.1 EIE92111.1 - 1.5 8.4 4.9 0.74 9.4 0.3 2.3 2 0 0 2 2 2 0 Probable zinc-binding domain DUF805 PF05656.9 EIE92112.1 - 0.041 13.7 0.4 0.067 13.0 0.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF805) Polyoma_agno PF01736.11 EIE92112.1 - 0.13 11.9 0.0 3.1 7.4 0.0 2.3 2 0 0 2 2 2 0 Polyomavirus agnoprotein DDE_3 PF13358.1 EIE92113.1 - 5.4e-16 58.6 0.1 6.7e-16 58.3 0.1 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE92113.1 - 0.0048 16.9 0.0 0.0073 16.4 0.0 1.4 1 1 0 1 1 1 1 Integrase core domain Transposase_21 PF02992.9 EIE92116.1 - 5.2e-11 42.0 0.4 8.3e-11 41.4 0.0 1.5 2 0 0 2 2 2 1 Transposase family tnp2 DDE_3 PF13358.1 EIE92118.1 - 1.9e-24 86.1 0.0 4e-24 85.0 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE92118.1 - 4.4e-12 45.8 0.3 1.5e-11 44.1 0.1 2.0 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.1 EIE92118.1 - 4.4e-07 29.3 0.0 2.1e-05 24.0 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain PAX PF00292.13 EIE92118.1 - 5.5e-05 22.8 0.0 0.00012 21.7 0.0 1.6 1 0 0 1 1 1 1 'Paired box' domain HTH_28 PF13518.1 EIE92118.1 - 6.7e-05 22.8 0.0 0.0013 18.6 0.0 2.8 3 0 0 3 3 2 1 Helix-turn-helix domain HTH_11 PF08279.7 EIE92118.1 - 7.4e-05 22.3 0.1 0.0013 18.2 0.0 2.4 2 0 0 2 2 2 1 HTH domain HTH_29 PF13551.1 EIE92118.1 - 0.00042 20.4 0.0 0.0016 18.5 0.0 2.0 1 1 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_ISL3 PF13542.1 EIE92118.1 - 0.00044 19.3 0.0 0.0031 16.6 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 rve PF00665.21 EIE92118.1 - 0.00048 20.2 0.0 0.0011 19.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Trp_repressor PF01371.14 EIE92118.1 - 0.00051 19.8 0.1 0.0025 17.6 0.0 2.1 2 0 0 2 2 2 1 Trp repressor protein DDE_Tnp_ISAZ013 PF07592.6 EIE92118.1 - 0.00083 18.1 0.0 0.035 12.8 0.0 2.1 2 0 0 2 2 2 1 Rhodopirellula transposase DDE domain HTH_7 PF02796.10 EIE92118.1 - 0.0012 18.6 0.7 0.051 13.4 0.1 2.8 3 0 0 3 3 2 1 Helix-turn-helix domain of resolvase HTH_26 PF13443.1 EIE92118.1 - 0.0032 17.6 0.1 0.056 13.6 0.0 2.8 3 0 0 3 3 2 1 Cro/C1-type HTH DNA-binding domain HTH_24 PF13412.1 EIE92118.1 - 0.0072 15.6 0.0 0.06 12.7 0.0 2.3 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_3 PF01381.17 EIE92118.1 - 0.011 15.6 0.1 0.07 12.9 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix CENP-B_N PF04218.8 EIE92118.1 - 0.029 13.7 0.1 0.21 11.0 0.1 2.2 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain HTH_38 PF13936.1 EIE92118.1 - 0.036 13.6 0.1 0.14 11.7 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain GerE PF00196.14 EIE92118.1 - 0.042 13.1 1.0 0.08 12.2 0.1 1.9 3 0 0 3 3 2 0 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.7 EIE92118.1 - 0.058 12.8 0.2 0.31 10.5 0.0 2.2 3 0 0 3 3 3 0 Sigma-70, region 4 COX16 PF14138.1 EIE92118.1 - 0.066 13.3 0.0 0.2 11.8 0.0 1.8 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 UPF0258 PF06789.7 EIE92118.1 - 0.081 12.9 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0258) LacI PF00356.16 EIE92118.1 - 0.11 12.1 0.0 6.9 6.3 0.0 2.7 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family AA_permease_2 PF13520.1 EIE92119.1 - 1.8e-43 148.6 43.0 2.3e-43 148.3 29.8 1.0 1 0 0 1 1 1 1 Amino acid permease FKBP_C PF00254.23 EIE92120.1 - 5.3e-32 109.7 0.0 6.1e-32 109.5 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF2611 PF11022.3 EIE92121.1 - 0.82 9.7 3.2 0.64 10.1 1.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2611) Flagellin_D3 PF08884.6 EIE92123.1 - 0.085 13.0 0.0 0.087 13.0 0.0 1.1 1 0 0 1 1 1 0 Flagellin D3 domain CHORD PF04968.7 EIE92124.1 - 1.2e-55 185.6 18.2 9.6e-28 96.2 4.5 2.4 2 0 0 2 2 2 2 CHORD CS PF04969.11 EIE92124.1 - 3e-16 59.7 3.4 5.8e-16 58.7 2.3 1.5 1 0 0 1 1 1 1 CS domain GSHPx PF00255.14 EIE92124.1 - 0.066 12.5 0.3 0.13 11.5 0.2 1.5 1 0 0 1 1 1 0 Glutathione peroxidase BTK PF00779.14 EIE92124.1 - 1.3 8.6 12.0 0.98 9.0 1.6 2.9 3 0 0 3 3 3 0 BTK motif Arrestin_C PF02752.17 EIE92125.1 - 1.3e-10 41.4 2.0 4.2e-09 36.6 0.5 2.3 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EIE92125.1 - 1.6e-06 28.0 0.0 7e-05 22.6 0.0 3.2 2 2 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 EIE92125.1 - 2.5e-06 27.1 0.0 9.2e-05 22.0 0.0 2.2 2 0 0 2 2 2 1 Arrestin_N terminal like SGT1 PF07093.6 EIE92126.1 - 3.8e-44 151.0 22.6 8.6e-44 149.8 15.7 1.5 1 1 0 1 1 1 1 SGT1 protein RAI16-like PF10257.4 EIE92127.1 - 2.1e-43 148.6 0.2 3.5e-43 147.9 0.2 1.4 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein Septin PF00735.13 EIE92128.1 - 1.8e-114 381.5 1.8 2.8e-114 380.9 1.2 1.2 1 0 0 1 1 1 1 Septin GTP_EFTU PF00009.22 EIE92128.1 - 3.9e-08 32.9 0.7 5.6e-07 29.1 0.1 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EIE92128.1 - 3.7e-07 30.1 0.0 8.8e-07 28.8 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EIE92128.1 - 6.7e-07 28.6 0.2 2.2e-06 26.9 0.1 1.9 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Ras PF00071.17 EIE92128.1 - 0.00026 20.4 2.2 0.00041 19.7 0.7 2.0 2 1 0 2 2 2 1 Ras family Gtr1_RagA PF04670.7 EIE92128.1 - 0.00029 20.0 0.0 0.00081 18.5 0.0 1.8 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EIE92128.1 - 0.00047 20.6 0.1 0.0017 18.8 0.1 2.0 1 0 0 1 1 1 1 Miro-like protein IIGP PF05049.8 EIE92128.1 - 0.0027 16.5 0.0 0.0051 15.6 0.0 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) FtsK_SpoIIIE PF01580.13 EIE92128.1 - 0.0029 17.1 0.3 0.0079 15.6 0.2 1.7 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_22 PF13401.1 EIE92128.1 - 0.0029 17.7 1.6 0.0049 17.0 0.0 2.1 2 1 0 2 2 2 1 AAA domain Pox_A32 PF04665.7 EIE92128.1 - 0.0053 16.0 0.9 0.043 13.1 0.1 2.2 2 0 0 2 2 2 1 Poxvirus A32 protein T2SE PF00437.15 EIE92128.1 - 0.0078 15.1 0.4 0.014 14.3 0.3 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AIG1 PF04548.11 EIE92128.1 - 0.0092 15.1 0.2 0.0092 15.1 0.1 1.9 2 0 0 2 2 2 1 AIG1 family RNA_helicase PF00910.17 EIE92128.1 - 0.011 15.8 0.3 0.052 13.7 0.1 2.2 1 1 1 2 2 2 0 RNA helicase Sigma54_activat PF00158.21 EIE92128.1 - 0.012 15.0 0.1 0.023 14.1 0.1 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.22 EIE92128.1 - 0.021 15.0 2.1 0.13 12.5 0.0 2.4 2 0 0 2 2 2 0 ABC transporter AAA_24 PF13479.1 EIE92128.1 - 0.024 14.2 0.3 0.042 13.4 0.2 1.7 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EIE92128.1 - 0.037 13.4 0.5 0.05 13.0 0.0 1.5 2 0 0 2 2 1 0 AAA-like domain AAA_33 PF13671.1 EIE92128.1 - 0.061 13.2 0.7 0.17 11.7 0.0 2.1 2 1 0 2 2 2 0 AAA domain NACHT PF05729.7 EIE92128.1 - 0.063 12.9 0.1 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.1 EIE92128.1 - 0.075 12.5 0.1 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain IstB_IS21 PF01695.12 EIE92128.1 - 0.076 12.4 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein MobB PF03205.9 EIE92128.1 - 0.12 12.0 1.0 0.3 10.7 0.6 1.8 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EIE92128.1 - 0.15 12.0 1.0 0.27 11.1 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain ATP_bind_1 PF03029.12 EIE92128.1 - 0.17 11.4 3.5 1.3 8.4 0.3 2.8 2 2 0 3 3 3 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.4 EIE92128.1 - 0.24 10.8 2.0 2.1 7.8 0.7 2.6 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF3987 PF13148.1 EIE92128.1 - 0.27 9.7 4.5 0.43 9.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Fzo_mitofusin PF04799.8 EIE92128.1 - 0.53 9.6 5.9 0.18 11.2 1.9 1.7 2 0 0 2 2 2 0 fzo-like conserved region Dynamin_N PF00350.18 EIE92128.1 - 0.82 9.4 11.4 0.44 10.3 0.1 3.3 3 1 1 4 4 4 0 Dynamin family UQ_con PF00179.21 EIE92129.1 - 3.4e-06 26.5 0.0 4.2e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme PP-binding PF00550.20 EIE92130.1 - 2.7e-14 53.1 0.1 3.3e-14 52.8 0.1 1.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 EIE92130.1 - 7e-07 29.1 0.3 9.4e-07 28.7 0.2 1.3 1 0 0 1 1 1 1 Acyl-carrier DUF1493 PF07377.7 EIE92130.1 - 0.066 13.3 0.1 0.11 12.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) NPR3 PF03666.8 EIE92133.1 - 1.4e-34 119.4 8.1 5.6e-18 64.7 0.4 2.2 1 1 1 2 2 2 2 Nitrogen Permease regulator of amino acid transport activity 3 DUF342 PF03961.8 EIE92134.1 - 0.13 10.6 0.1 0.22 9.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF4050 PF13259.1 EIE92134.1 - 0.84 9.5 4.0 0.5 10.3 0.1 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF4050) Baculo_PEP_C PF04513.7 EIE92134.1 - 3.5 7.4 8.3 0.31 10.8 0.5 2.8 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Nucleoporin_N PF08801.6 EIE92135.1 - 2.9e-44 151.4 3.1 5e-44 150.7 2.1 1.3 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.9 EIE92135.1 - 2.6e-33 115.4 7.1 5.3e-33 114.4 4.9 1.4 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal FYVE PF01363.16 EIE92137.1 - 1.2e-19 69.8 9.7 1.2e-19 69.8 6.7 2.6 2 1 0 2 2 2 1 FYVE zinc finger Elf1 PF05129.8 EIE92137.1 - 0.028 14.1 3.5 0.33 10.6 0.4 2.4 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like HypA PF01155.14 EIE92137.1 - 0.047 13.3 9.7 2.5 7.8 0.0 2.6 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Sporozoite_P67 PF05642.6 EIE92137.1 - 0.1 10.4 2.4 0.13 10.0 1.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FYVE_2 PF02318.11 EIE92137.1 - 0.46 10.3 17.5 0.11 12.4 7.2 3.0 2 1 1 3 3 3 0 FYVE-type zinc finger Rer1 PF03248.8 EIE92138.1 - 3.7e-56 189.4 3.4 4.2e-56 189.3 2.4 1.0 1 0 0 1 1 1 1 Rer1 family DUF948 PF06103.6 EIE92139.1 - 0.18 11.7 0.1 0.18 11.7 0.1 3.7 2 1 3 5 5 5 0 Bacterial protein of unknown function (DUF948) Baculo_PEP_C PF04513.7 EIE92139.1 - 0.81 9.5 3.2 4 7.2 0.1 3.0 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Bacillus_HBL PF05791.6 EIE92139.1 - 5.3 6.3 24.6 1.8 7.8 2.8 4.4 2 2 2 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) TPR_MLP1_2 PF07926.7 EIE92139.1 - 5.4 6.7 36.9 0.055 13.2 3.0 4.2 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein PTPA PF03095.10 EIE92140.1 - 1.8e-109 365.5 0.5 2.3e-108 361.8 0.4 1.9 1 1 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein MAM33 PF02330.11 EIE92141.1 - 4.8e-37 127.7 5.0 6.1e-37 127.3 3.5 1.1 1 0 0 1 1 1 1 Mitochondrial glycoprotein DDE_3 PF13358.1 EIE92142.1 - 2.1e-29 102.1 0.0 4.6e-29 101.0 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 EIE92142.1 - 4.1e-10 39.7 0.1 1.7e-09 37.8 0.0 1.9 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.1 EIE92142.1 - 7.5e-08 33.0 0.3 1.9e-07 31.7 0.0 1.9 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.1 EIE92142.1 - 3.5e-06 26.9 3.1 1.2e-05 25.1 0.1 2.9 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_23 PF13384.1 EIE92142.1 - 5.7e-05 22.6 2.4 0.00057 19.4 0.0 2.9 3 0 0 3 3 3 1 Homeodomain-like domain rve PF00665.21 EIE92142.1 - 0.0011 19.0 0.0 0.0048 16.9 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain HTH_Tnp_1 PF01527.15 EIE92142.1 - 0.012 15.5 2.5 0.015 15.2 0.3 2.1 2 0 0 2 2 2 0 Transposase HTH_17 PF12728.2 EIE92142.1 - 0.015 15.5 0.3 2.6 8.3 0.2 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain DDE_1 PF03184.14 EIE92142.1 - 0.017 14.3 0.0 0.39 9.8 0.0 2.3 2 0 0 2 2 2 0 DDE superfamily endonuclease HTH_Tnp_ISL3 PF13542.1 EIE92142.1 - 0.047 12.8 0.1 0.094 11.9 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 TFCD_C PF12612.3 EIE92143.1 - 0.011 15.1 0.0 0.022 14.2 0.0 1.5 1 0 0 1 1 1 0 Tubulin folding cofactor D C terminal DDE_3 PF13358.1 EIE92144.1 - 2.1e-29 102.1 0.0 4.6e-29 101.0 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 EIE92144.1 - 4.1e-10 39.7 0.1 1.7e-09 37.8 0.0 1.9 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.1 EIE92144.1 - 7.5e-08 33.0 0.3 1.9e-07 31.7 0.0 1.9 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.1 EIE92144.1 - 3.5e-06 26.9 3.1 1.2e-05 25.1 0.1 2.9 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_23 PF13384.1 EIE92144.1 - 5.7e-05 22.6 2.4 0.00057 19.4 0.0 2.9 3 0 0 3 3 3 1 Homeodomain-like domain rve PF00665.21 EIE92144.1 - 0.0011 19.0 0.0 0.0048 16.9 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain HTH_Tnp_1 PF01527.15 EIE92144.1 - 0.012 15.5 2.5 0.015 15.2 0.3 2.1 2 0 0 2 2 2 0 Transposase HTH_17 PF12728.2 EIE92144.1 - 0.015 15.5 0.3 2.6 8.3 0.2 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain DDE_1 PF03184.14 EIE92144.1 - 0.017 14.3 0.0 0.39 9.8 0.0 2.3 2 0 0 2 2 2 0 DDE superfamily endonuclease HTH_Tnp_ISL3 PF13542.1 EIE92144.1 - 0.047 12.8 0.1 0.094 11.9 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Inhibitor_I9 PF05922.11 EIE92146.1 - 5e-11 43.0 0.1 6.2e-11 42.7 0.1 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I9 DUF4354 PF14263.1 EIE92146.1 - 0.06 13.0 0.1 0.069 12.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4354) Sod_Cu PF00080.15 EIE92147.1 - 1.7e-36 125.4 1.3 1.9e-36 125.3 0.3 1.4 2 0 0 2 2 2 1 Copper/zinc superoxide dismutase (SODC) HMA PF00403.21 EIE92147.1 - 0.00073 19.6 0.4 0.0016 18.5 0.3 1.5 1 0 0 1 1 1 1 Heavy-metal-associated domain DUF1939 PF09154.5 EIE92147.1 - 0.042 13.7 0.0 0.096 12.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1939) Prefoldin_2 PF01920.15 EIE92148.1 - 1.2e-24 86.1 5.1 1.3e-24 85.9 3.5 1.0 1 0 0 1 1 1 1 Prefoldin subunit IncA PF04156.9 EIE92148.1 - 0.002 17.7 3.6 0.0028 17.2 2.5 1.2 1 0 0 1 1 1 1 IncA protein DUF2935 PF11155.3 EIE92148.1 - 0.0021 18.1 0.3 0.0026 17.8 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2935) DASH_Dad3 PF08656.5 EIE92148.1 - 0.0038 16.8 0.8 0.0098 15.5 0.1 1.8 2 0 0 2 2 2 1 DASH complex subunit Dad3 UBN2 PF14223.1 EIE92148.1 - 0.0065 16.2 0.6 2.5 7.9 0.0 2.1 2 0 0 2 2 2 2 gag-polypeptide of LTR copia-type BLOC1_2 PF10046.4 EIE92148.1 - 0.0097 16.0 3.6 0.068 13.3 0.2 2.1 2 0 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 KaiC PF06745.8 EIE92148.1 - 0.013 14.5 0.0 0.018 14.1 0.0 1.3 1 1 0 1 1 1 0 KaiC EzrA PF06160.7 EIE92148.1 - 0.015 13.4 2.9 0.21 9.7 0.0 2.0 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA TMF_TATA_bd PF12325.3 EIE92148.1 - 0.028 14.1 3.9 1.7 8.3 0.3 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding IFT57 PF10498.4 EIE92148.1 - 0.037 12.7 5.8 0.39 9.4 0.2 2.0 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 DASH_Spc34 PF08657.5 EIE92148.1 - 0.045 13.4 1.0 0.045 13.4 0.7 2.0 1 1 0 2 2 2 0 DASH complex subunit Spc34 TBPIP PF07106.8 EIE92148.1 - 0.056 12.9 3.7 0.072 12.6 0.2 2.0 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) HsbA PF12296.3 EIE92148.1 - 0.068 13.0 0.1 12 5.7 0.0 2.1 2 0 0 2 2 2 0 Hydrophobic surface binding protein A Fib_alpha PF08702.5 EIE92148.1 - 0.13 12.4 1.4 0.27 11.3 1.0 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Syntaxin-6_N PF09177.6 EIE92148.1 - 0.13 12.7 1.9 0.83 10.0 0.2 2.1 1 1 0 2 2 2 0 Syntaxin 6, N-terminal DUF4200 PF13863.1 EIE92148.1 - 0.15 12.0 5.5 0.31 10.9 1.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) GrpE PF01025.14 EIE92148.1 - 0.15 11.5 3.4 4.5 6.7 0.1 2.1 2 0 0 2 2 2 0 GrpE Tho2 PF11262.3 EIE92148.1 - 0.17 10.9 1.8 1 8.3 0.3 2.0 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 TPR_MLP1_2 PF07926.7 EIE92148.1 - 0.19 11.4 4.8 1.3 8.7 0.3 2.0 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF342 PF03961.8 EIE92148.1 - 0.2 10.0 2.8 0.31 9.4 2.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF342) Kinetocho_Slk19 PF12709.2 EIE92148.1 - 0.41 10.7 5.3 5.2 7.2 0.3 2.2 2 0 0 2 2 2 0 Central kinetochore-associated Tup_N PF08581.5 EIE92148.1 - 0.49 10.6 4.6 0.46 10.7 0.5 2.2 2 0 0 2 2 2 0 Tup N-terminal DivIC PF04977.10 EIE92148.1 - 0.55 9.7 4.0 1.4 8.4 0.9 2.1 2 0 0 2 2 2 0 Septum formation initiator TMF_DNA_bd PF12329.3 EIE92148.1 - 0.65 9.8 4.1 0.39 10.5 0.5 2.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF3552 PF12072.3 EIE92148.1 - 0.77 8.9 4.8 0.15 11.2 0.9 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) DivIVA PF05103.8 EIE92148.1 - 0.97 9.4 6.5 0.88 9.6 0.5 2.0 1 1 1 2 2 2 0 DivIVA protein bZIP_1 PF00170.16 EIE92148.1 - 2.1 8.3 6.5 0.36 10.8 0.4 2.2 2 1 0 2 2 2 0 bZIP transcription factor WD40 PF00400.27 EIE92149.1 - 5.8e-06 25.9 1.2 0.00012 21.8 0.0 2.9 3 0 0 3 3 3 1 WD domain, G-beta repeat EI24 PF07264.6 EIE92150.1 - 3.2e-21 75.7 8.1 4.6e-21 75.2 5.6 1.2 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) 4HBT PF03061.17 EIE92151.1 - 5.5e-13 48.8 0.0 7.8e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.1 EIE92151.1 - 0.00012 22.4 0.0 0.00016 22.0 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.12 EIE92151.1 - 0.0088 15.0 0.3 0.016 14.1 0.2 1.3 1 0 0 1 1 1 1 Acyl-ACP thioesterase Calreticulin PF00262.13 EIE92152.1 - 6.3e-107 357.4 10.0 6.3e-107 357.4 6.9 1.5 2 0 0 2 2 2 1 Calreticulin family Tropomyosin_1 PF12718.2 EIE92154.1 - 9.3e-07 28.7 28.5 9.3e-07 28.7 19.8 11.1 1 1 10 11 11 11 6 Tropomyosin like TPR_MLP1_2 PF07926.7 EIE92154.1 - 0.00084 19.0 63.2 0.0017 18.1 15.9 11.4 3 2 7 10 10 10 4 TPR/MLP1/MLP2-like protein LPP PF04728.8 EIE92154.1 - 3.1 7.6 20.2 5.3 6.9 0.1 7.9 8 1 2 10 10 10 0 Lipoprotein leucine-zipper Acetyltransf_1 PF00583.19 EIE92156.1 - 2.1e-08 34.0 0.0 2.8e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EIE92156.1 - 2.8e-05 24.1 0.0 7.2e-05 22.8 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EIE92156.1 - 0.028 14.5 0.0 0.038 14.1 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EIE92156.1 - 0.086 12.7 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Pectinesterase PF01095.14 EIE92158.1 - 9.6e-48 162.2 9.8 2e-47 161.2 6.8 1.4 1 1 0 1 1 1 1 Pectinesterase DUF1565 PF07602.6 EIE92158.1 - 0.057 12.5 2.8 0.075 12.1 1.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1565) Pectinesterase PF01095.14 EIE92159.1 - 2.2e-44 151.2 6.0 4.1e-44 150.3 4.2 1.4 1 1 0 1 1 1 1 Pectinesterase Adeno_E1B_55K PF01696.12 EIE92159.1 - 0.017 13.6 0.4 0.027 12.9 0.3 1.3 1 0 0 1 1 1 0 Adenovirus EB1 55K protein / large t-antigen Aa_trans PF01490.13 EIE92160.1 - 8.9e-52 175.9 26.1 1.2e-51 175.4 18.1 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Spore_permease PF03845.8 EIE92160.1 - 0.00018 20.2 26.1 0.00025 19.7 18.1 1.2 1 0 0 1 1 1 1 Spore germination protein Claudin_2 PF13903.1 EIE92160.1 - 0.0087 15.7 8.0 2.1 7.9 4.0 3.1 2 1 0 2 2 2 2 PMP-22/EMP/MP20/Claudin tight junction VIT1 PF01988.14 EIE92160.1 - 0.011 15.1 0.0 0.011 15.1 0.0 3.1 2 1 1 3 3 3 0 VIT family BSP PF04450.7 EIE92161.1 - 0.079 12.4 0.1 0.083 12.3 0.1 1.0 1 0 0 1 1 1 0 Peptidase of plants and bacteria PALP PF00291.20 EIE92162.1 - 2.3e-41 142.0 0.3 2.9e-41 141.6 0.2 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DAGK_cat PF00781.19 EIE92162.1 - 0.00076 18.9 0.0 0.0013 18.1 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Aminotran_1_2 PF00155.16 EIE92162.1 - 0.024 13.5 0.0 0.039 12.8 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II FancD2 PF14631.1 EIE92163.1 - 6.4e-77 258.8 10.3 5.1e-73 245.9 6.2 2.3 1 1 1 2 2 2 2 Fanconi anaemia protein FancD2 nuclease FANCI_S2 PF14676.1 EIE92163.1 - 1.7 8.5 7.3 5 7.0 0.1 3.0 2 1 0 3 3 3 0 FANCI solenoid 2 FancD2 PF14631.1 EIE92164.1 - 4.7e-67 226.1 5.9 3.9e-46 156.8 0.3 2.4 1 1 0 2 2 2 2 Fanconi anaemia protein FancD2 nuclease EB PF01683.13 EIE92167.1 - 0.00079 19.4 7.5 0.00079 19.4 5.2 5.3 1 1 3 4 4 4 3 EB module LeuA_dimer PF08502.5 EIE92169.1 - 0.08 12.7 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 LeuA allosteric (dimerisation) domain Kelch_4 PF13418.1 EIE92170.1 - 4.5e-25 87.1 14.2 3.7e-08 33.0 0.0 5.1 4 1 1 5 5 5 5 Galactose oxidase, central domain Kelch_3 PF13415.1 EIE92170.1 - 5.3e-22 77.3 17.6 1.1e-09 38.1 0.1 5.4 5 1 1 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.1 EIE92170.1 - 8.3e-22 76.7 1.5 1.7e-06 27.8 0.1 5.0 4 1 0 4 4 4 4 Kelch motif Kelch_6 PF13964.1 EIE92170.1 - 3.4e-20 71.3 10.7 1.2e-06 28.3 0.0 5.0 3 2 1 4 4 4 4 Kelch motif Kelch_1 PF01344.20 EIE92170.1 - 6.3e-19 67.2 10.2 2e-06 27.2 0.0 4.9 4 1 0 4 4 4 4 Kelch motif Kelch_2 PF07646.10 EIE92170.1 - 5.6e-15 54.4 4.9 0.015 15.0 0.1 4.5 5 0 0 5 5 5 4 Kelch motif EB PF01683.13 EIE92171.1 - 0.00079 19.4 7.5 0.00079 19.4 5.2 5.3 1 1 3 4 4 4 3 EB module Pkinase PF00069.20 EIE92172.1 - 1.4e-57 194.8 0.0 2.3e-57 194.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE92172.1 - 2.2e-22 79.3 0.0 3.5e-22 78.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIE92172.1 - 0.00044 20.0 0.0 0.0011 18.7 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EIE92172.1 - 0.00059 18.8 0.0 0.0013 17.7 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Surface_Ag_2 PF01617.12 EIE92173.1 - 0.0034 16.6 0.2 0.0046 16.2 0.1 1.1 1 0 0 1 1 1 1 Surface antigen DUF3979 PF13141.1 EIE92173.1 - 0.067 13.0 0.2 0.094 12.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3979) COG2 PF06148.6 EIE92173.1 - 0.096 12.5 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Tropomyosin_1 PF12718.2 EIE92174.1 - 1.9e-21 76.4 31.2 2e-13 50.3 10.7 2.1 1 1 1 2 2 2 2 Tropomyosin like Tropomyosin PF00261.15 EIE92174.1 - 3.4e-09 36.1 27.8 4.1e-09 35.8 19.2 1.0 1 0 0 1 1 1 1 Tropomyosin TMF_DNA_bd PF12329.3 EIE92174.1 - 0.00023 20.8 29.8 0.00079 19.1 10.0 2.5 2 1 0 2 2 2 1 TATA element modulatory factor 1 DNA binding Spc7 PF08317.6 EIE92174.1 - 0.00026 19.7 18.1 0.0003 19.5 12.6 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein ATG16 PF08614.6 EIE92174.1 - 0.0011 18.8 22.3 0.0035 17.1 6.7 2.0 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) Reo_sigmaC PF04582.7 EIE92174.1 - 0.0012 18.1 1.2 0.002 17.4 0.5 1.5 1 1 0 1 1 1 1 Reovirus sigma C capsid protein FH2 PF02181.18 EIE92174.1 - 0.0014 17.6 8.5 0.0016 17.3 5.9 1.1 1 0 0 1 1 1 1 Formin Homology 2 Domain SCP-1 PF05483.7 EIE92174.1 - 0.0022 15.8 8.8 0.0022 15.8 6.1 1.9 1 1 1 2 2 2 1 Synaptonemal complex protein 1 (SCP-1) DUF812 PF05667.6 EIE92174.1 - 0.0022 16.6 16.1 0.0026 16.3 11.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) CENP-F_leu_zip PF10473.4 EIE92174.1 - 0.0028 17.5 25.1 0.07 12.9 7.4 2.2 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ADIP PF11559.3 EIE92174.1 - 0.003 17.4 20.6 0.078 12.8 7.2 2.2 1 1 0 1 1 1 1 Afadin- and alpha -actinin-Binding Mod_r PF07200.8 EIE92174.1 - 0.003 17.4 17.8 0.0036 17.2 12.3 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein DUF869 PF05911.6 EIE92174.1 - 0.0033 15.7 17.3 0.0041 15.4 12.0 1.1 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) CorA PF01544.13 EIE92174.1 - 0.0034 16.4 12.4 0.0044 16.1 8.6 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Filament PF00038.16 EIE92174.1 - 0.0034 16.9 19.3 0.0045 16.4 13.2 1.3 1 1 0 1 1 1 1 Intermediate filament protein IncA PF04156.9 EIE92174.1 - 0.005 16.4 25.3 0.0084 15.7 17.5 1.4 1 1 0 1 1 1 1 IncA protein RmuC PF02646.11 EIE92174.1 - 0.005 15.7 7.4 0.007 15.2 4.5 1.6 1 1 0 1 1 1 1 RmuC family Striatin PF08232.7 EIE92174.1 - 0.0051 17.1 17.5 0.01 16.1 12.1 1.5 1 1 0 1 1 1 1 Striatin family DUF4201 PF13870.1 EIE92174.1 - 0.0067 15.8 19.6 0.0072 15.7 13.1 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4201) MAD PF05557.8 EIE92174.1 - 0.0096 14.0 22.9 0.011 13.8 15.9 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein Fmp27_WPPW PF10359.4 EIE92174.1 - 0.0096 14.3 14.6 0.017 13.5 10.1 1.4 1 1 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain GAS PF13851.1 EIE92174.1 - 0.0099 15.0 23.4 0.021 14.0 16.2 1.5 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding Vac_Fusion PF02346.11 EIE92174.1 - 0.0099 15.2 7.9 0.037 13.4 0.4 3.0 1 1 1 3 3 3 1 Chordopoxvirus fusion protein Laminin_II PF06009.7 EIE92174.1 - 0.012 15.4 12.6 0.023 14.4 4.7 2.0 1 1 1 2 2 2 0 Laminin Domain II Myosin_tail_1 PF01576.14 EIE92174.1 - 0.015 13.0 24.0 0.019 12.6 16.6 1.2 1 0 0 1 1 1 0 Myosin tail WXG100 PF06013.7 EIE92174.1 - 0.026 14.4 11.6 0.74 9.8 0.4 3.2 2 1 1 3 3 3 0 Proteins of 100 residues with WXG CALCOCO1 PF07888.6 EIE92174.1 - 0.027 12.8 14.6 0.032 12.5 9.1 1.6 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Nup54 PF13874.1 EIE92174.1 - 0.034 13.8 15.0 0.064 12.9 4.7 2.3 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 TBPIP PF07106.8 EIE92174.1 - 0.034 13.7 20.6 0.015 14.8 7.1 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) KCNQ_channel PF03520.9 EIE92174.1 - 0.034 13.4 1.6 0.045 13.0 0.8 1.5 1 1 0 1 1 1 0 KCNQ voltage-gated potassium channel MCPsignal PF00015.16 EIE92174.1 - 0.035 13.6 5.0 0.045 13.2 3.5 1.3 1 1 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain AAA_27 PF13514.1 EIE92174.1 - 0.036 11.7 18.5 0.05 11.2 12.8 1.2 1 0 0 1 1 1 0 AAA domain APG6 PF04111.7 EIE92174.1 - 0.041 12.9 26.6 0.39 9.7 17.9 1.9 1 1 0 1 1 1 0 Autophagy protein Apg6 Spectrin PF00435.16 EIE92174.1 - 0.044 14.0 19.9 0.076 13.3 7.0 2.1 1 1 1 2 2 2 0 Spectrin repeat OEP PF02321.13 EIE92174.1 - 0.049 13.2 21.1 0.1 12.1 14.6 1.5 1 1 0 1 1 1 0 Outer membrane efflux protein DUF2802 PF10975.3 EIE92174.1 - 0.055 13.2 9.9 2.3 8.0 0.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2802) Fib_alpha PF08702.5 EIE92174.1 - 0.056 13.5 10.9 0.23 11.5 7.4 2.2 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family TMF_TATA_bd PF12325.3 EIE92174.1 - 0.06 13.0 25.5 0.89 9.2 17.6 2.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Pinin_SDK_N PF04697.8 EIE92174.1 - 0.063 13.3 0.4 0.12 12.4 0.3 1.6 1 0 0 1 1 1 0 pinin/SDK conserved region BLOC1_2 PF10046.4 EIE92174.1 - 0.067 13.3 15.9 1.7 8.8 3.2 2.8 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TPR_MLP1_2 PF07926.7 EIE92174.1 - 0.091 12.5 25.5 0.35 10.6 17.7 1.9 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Bcr-Abl_Oligo PF09036.5 EIE92174.1 - 0.091 12.7 4.3 2.5 8.1 0.5 2.3 1 1 1 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain AAA_13 PF13166.1 EIE92174.1 - 0.095 11.1 19.8 0.05 12.0 5.9 1.9 1 1 1 2 2 2 0 AAA domain Prefoldin_2 PF01920.15 EIE92174.1 - 0.11 12.2 26.7 2.5 7.8 5.3 3.1 1 1 2 3 3 3 0 Prefoldin subunit DUF2968 PF11180.3 EIE92174.1 - 0.11 11.8 16.0 0.18 11.1 4.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) EzrA PF06160.7 EIE92174.1 - 0.12 10.4 18.8 0.25 9.4 13.1 1.4 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA NPV_P10 PF05531.7 EIE92174.1 - 0.13 12.5 9.0 29 5.0 6.2 3.0 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Syntaxin PF00804.20 EIE92174.1 - 0.13 12.4 16.0 4.1 7.6 11.1 2.1 1 1 0 1 1 1 0 Syntaxin V_ATPase_I PF01496.14 EIE92174.1 - 0.14 9.9 11.0 0.19 9.5 7.6 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc24 PF08286.6 EIE92174.1 - 0.14 11.8 23.1 0.78 9.4 2.8 3.0 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 FliD_C PF07195.7 EIE92174.1 - 0.17 11.1 10.0 0.28 10.4 1.7 2.2 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Seryl_tRNA_N PF02403.17 EIE92174.1 - 0.2 11.7 22.0 0.83 9.6 1.5 3.0 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF1664 PF07889.7 EIE92174.1 - 0.2 11.4 8.8 0.33 10.7 1.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Prefoldin PF02996.12 EIE92174.1 - 0.2 11.2 21.5 0.18 11.4 2.6 3.1 1 1 2 3 3 3 0 Prefoldin subunit KLRAQ PF10205.4 EIE92174.1 - 0.22 11.5 14.0 0.46 10.5 5.2 2.1 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein DUF972 PF06156.8 EIE92174.1 - 0.23 11.8 18.6 0.19 12.1 5.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Vps5 PF09325.5 EIE92174.1 - 0.3 10.2 14.8 0.34 10.1 5.4 2.7 1 1 1 2 2 2 0 Vps5 C terminal like Hemerythrin PF01814.18 EIE92174.1 - 0.31 11.1 10.9 0.99 9.5 2.1 2.2 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain Syntaxin-6_N PF09177.6 EIE92174.1 - 0.41 11.0 15.2 0.47 10.8 5.1 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF3450 PF11932.3 EIE92174.1 - 0.41 9.8 18.2 0.79 8.9 5.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Transposase_22 PF02994.9 EIE92174.1 - 0.45 8.9 14.6 0.035 12.5 3.4 2.0 1 1 1 2 2 2 0 L1 transposable element DUF948 PF06103.6 EIE92174.1 - 0.47 10.3 7.3 4.7 7.1 0.5 2.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF724 PF05266.9 EIE92174.1 - 0.52 9.9 20.4 0.13 11.8 7.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) XhlA PF10779.4 EIE92174.1 - 0.53 10.2 18.8 0.6 10.0 4.9 2.5 2 1 1 3 3 3 0 Haemolysin XhlA DUF641 PF04859.7 EIE92174.1 - 0.54 10.0 16.5 0.34 10.6 3.9 2.3 1 1 0 2 2 2 0 Plant protein of unknown function (DUF641) NYD-SP28 PF14772.1 EIE92174.1 - 0.55 10.3 17.7 0.22 11.6 9.1 2.1 1 1 1 2 2 2 0 Sperm tail Uteroglobin PF01099.12 EIE92174.1 - 0.57 10.0 5.4 0.61 9.9 0.3 2.8 3 0 0 3 3 3 0 Uteroglobin family DUF4618 PF15397.1 EIE92174.1 - 0.58 9.4 16.4 0.79 9.0 10.6 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) AHS1 PF02682.11 EIE92174.1 - 0.62 9.4 3.6 0.65 9.4 1.5 1.6 1 1 1 2 2 2 0 Allophanate hydrolase subunit 1 DUF1465 PF07323.7 EIE92174.1 - 0.67 9.5 9.1 0.56 9.7 1.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1465) Mnd1 PF03962.10 EIE92174.1 - 0.77 9.4 21.3 2.1 7.9 7.6 2.0 1 1 1 2 2 2 0 Mnd1 family HOOK PF05622.7 EIE92174.1 - 0.79 7.4 19.9 3.2 5.4 1.5 1.9 1 1 0 1 1 1 0 HOOK protein V-ATPase_C PF03223.10 EIE92174.1 - 0.79 8.5 8.7 3 6.6 1.4 2.3 1 1 1 2 2 2 0 V-ATPase subunit C FUSC PF04632.7 EIE92174.1 - 0.84 7.9 3.7 0.9 7.8 2.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Allexi_40kDa PF05549.6 EIE92174.1 - 0.92 8.7 6.9 1.2 8.3 3.6 1.6 1 1 1 2 2 2 0 Allexivirus 40kDa protein FliD_N PF02465.13 EIE92174.1 - 0.92 9.9 8.4 0.4 11.0 0.6 2.4 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DivIC PF04977.10 EIE92174.1 - 0.94 9.0 27.7 0.37 10.2 3.3 3.1 1 1 2 3 3 3 0 Septum formation initiator Atg14 PF10186.4 EIE92174.1 - 0.94 8.3 16.9 1.1 8.1 10.6 1.7 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Exonuc_VII_L PF02601.10 EIE92174.1 - 0.94 8.6 12.2 1.1 8.3 8.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit PspA_IM30 PF04012.7 EIE92174.1 - 1.1 8.5 22.7 6.2 6.1 15.8 1.9 1 1 0 1 1 1 0 PspA/IM30 family Med4 PF10018.4 EIE92174.1 - 1.2 8.4 20.2 1.4 8.2 5.6 2.7 1 1 2 3 3 3 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF904 PF06005.7 EIE92174.1 - 1.2 9.4 29.3 0.072 13.3 2.7 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF904) DUF4252 PF14060.1 EIE92174.1 - 1.3 8.5 7.1 3.9 6.9 4.2 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4252) DUF4559 PF15112.1 EIE92174.1 - 1.3 8.0 11.9 1.6 7.8 8.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) ERM PF00769.14 EIE92174.1 - 1.4 8.3 26.5 0.65 9.4 7.9 1.9 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Peptidase_S46 PF10459.4 EIE92174.1 - 1.4 7.2 10.3 1.6 7.0 7.1 1.0 1 0 0 1 1 1 0 Peptidase S46 FlxA PF14282.1 EIE92174.1 - 1.5 8.7 14.5 0.71 9.8 1.6 3.0 1 1 2 3 3 3 0 FlxA-like protein DUF3552 PF12072.3 EIE92174.1 - 1.5 7.9 23.8 3 7.0 16.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) COG2 PF06148.6 EIE92174.1 - 1.6 8.6 14.2 0.44 10.4 4.8 2.1 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 SlyX PF04102.7 EIE92174.1 - 1.9 8.9 18.2 4.6 7.6 2.5 2.6 1 1 2 3 3 3 0 SlyX DUF2730 PF10805.3 EIE92174.1 - 2 8.2 10.7 39 4.0 6.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) PilJ PF13675.1 EIE92174.1 - 2 8.7 11.5 21 5.4 7.9 2.0 1 1 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF342 PF03961.8 EIE92174.1 - 2.1 6.6 19.6 0.19 10.1 8.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Snapin_Pallidin PF14712.1 EIE92174.1 - 2.3 8.6 15.6 7.5 6.9 0.9 2.5 1 1 1 2 2 2 0 Snapin/Pallidin TMPIT PF07851.8 EIE92174.1 - 2.5 7.1 9.8 3 6.8 6.8 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF4200 PF13863.1 EIE92174.1 - 2.6 7.9 25.0 5.9 6.8 9.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) AKNA PF12443.3 EIE92174.1 - 2.7 8.0 12.3 2.6 8.1 0.7 2.8 1 1 1 2 2 2 0 AT-hook-containing transcription factor Adeno_PIX PF03955.9 EIE92174.1 - 2.8 8.4 10.9 2.9 8.4 3.1 2.1 1 1 1 2 2 2 0 Adenovirus hexon-associated protein (IX) Baculo_PEP_C PF04513.7 EIE92174.1 - 2.8 7.7 6.8 19 5.0 4.7 2.0 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1049 PF06305.6 EIE92174.1 - 2.8 7.4 10.8 10 5.6 0.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) Imm42 PF15601.1 EIE92174.1 - 2.9 7.3 6.1 1.9 7.9 0.7 2.1 1 1 0 2 2 2 0 Immunity protein 42 DUF2203 PF09969.4 EIE92174.1 - 3.4 7.9 12.6 5.7 7.1 3.2 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Laminin_I PF06008.9 EIE92174.1 - 3.8 6.7 23.2 8.3 5.6 14.1 1.9 1 1 1 2 2 2 0 Laminin Domain I Nsp1_C PF05064.8 EIE92174.1 - 4.2 7.0 16.8 1.9 8.1 5.5 2.3 1 1 1 2 2 2 0 Nsp1-like C-terminal region DUF2570 PF10828.3 EIE92174.1 - 4.4 6.9 12.6 1.2 8.7 6.5 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) Sec34 PF04136.10 EIE92174.1 - 4.4 6.9 10.8 8.6 6.0 0.4 2.8 1 1 2 3 3 3 0 Sec34-like family Pox_A_type_inc PF04508.7 EIE92174.1 - 4.6 7.2 18.1 2.4 8.1 1.1 4.4 4 1 0 4 4 3 0 Viral A-type inclusion protein repeat Mac PF12464.3 EIE92174.1 - 4.7 7.3 8.3 1.3e+02 2.6 5.8 2.7 1 1 0 1 1 1 0 Maltose acetyltransferase Jnk-SapK_ap_N PF09744.4 EIE92174.1 - 4.7 7.1 20.6 2.5 8.1 6.9 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Tox-ODYAM1 PF15642.1 EIE92174.1 - 4.8 5.7 12.8 5.7 5.4 8.9 1.0 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus Rotamase PF00639.16 EIE92174.1 - 5.1 7.9 14.2 2.7 8.7 0.6 3.0 1 1 2 3 3 3 0 PPIC-type PPIASE domain GrpE PF01025.14 EIE92174.1 - 5.4 6.5 25.4 2.5 7.6 4.7 2.6 1 1 1 2 2 2 0 GrpE FlaC_arch PF05377.6 EIE92174.1 - 5.6 6.9 13.5 22 5.0 0.1 3.4 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) Peptidase_C6 PF00851.13 EIE92174.1 - 6.1 5.3 6.8 6.9 5.1 4.7 1.0 1 0 0 1 1 1 0 Helper component proteinase Prominin PF05478.6 EIE92174.1 - 6.2 4.2 8.8 7.2 3.9 6.1 1.1 1 0 0 1 1 1 0 Prominin CDC37_N PF03234.9 EIE92174.1 - 6.5 7.0 15.8 14 5.9 11.0 1.5 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding Cauli_AT PF03233.8 EIE92174.1 - 6.6 6.4 10.0 0.62 9.7 1.7 2.0 1 1 1 2 2 2 0 Aphid transmission protein EMP24_GP25L PF01105.19 EIE92174.1 - 6.9 6.3 12.5 2 8.1 4.1 2.4 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF4337 PF14235.1 EIE92174.1 - 7 6.4 22.0 3.2 7.5 2.5 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) Macoilin PF09726.4 EIE92174.1 - 7.7 4.6 17.3 8.9 4.4 12.0 1.1 1 0 0 1 1 1 0 Transmembrane protein CENP-Q PF13094.1 EIE92174.1 - 8.4 6.3 29.3 2.9 7.8 10.2 2.0 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF3391 PF11871.3 EIE92174.1 - 9.4 6.4 7.8 12 6.1 2.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3391) MutS_III PF05192.13 EIE92174.1 - 9.4 5.9 9.2 11 5.6 6.4 1.1 1 0 0 1 1 1 0 MutS domain III FemAB PF02388.11 EIE92174.1 - 9.8 4.7 16.2 0.81 8.3 4.5 2.0 1 1 1 2 2 2 0 FemAB family RGP PF03214.8 EIE92176.1 - 0.097 11.3 0.0 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 Reversibly glycosylated polypeptide PIF1 PF05970.9 EIE92177.1 - 2.4e-70 237.3 0.0 3.7e-70 236.7 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.1 EIE92177.1 - 1.1e-65 220.8 0.0 2.8e-65 219.5 0.0 1.7 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.1 EIE92177.1 - 0.00018 21.1 0.0 0.00037 20.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 EIE92177.1 - 0.00075 19.3 0.0 0.0017 18.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EIE92177.1 - 0.0021 17.7 0.0 0.0045 16.7 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 EIE92177.1 - 0.0026 17.5 0.0 0.0088 15.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EIE92177.1 - 0.018 15.0 0.0 0.11 12.4 0.0 2.3 3 0 0 3 3 3 0 AAA ATPase domain Sigma54_activat PF00158.21 EIE92177.1 - 0.03 13.7 0.0 0.054 12.9 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain T2SE PF00437.15 EIE92177.1 - 0.058 12.2 0.0 0.098 11.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.11 EIE92177.1 - 0.064 12.4 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein TrwB_AAD_bind PF10412.4 EIE92177.1 - 0.074 11.6 0.0 0.12 10.9 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_22 PF13401.1 EIE92177.1 - 0.14 12.2 0.0 0.59 10.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain GFA PF04828.9 EIE92178.1 - 0.0097 15.8 0.8 0.0097 15.8 0.6 2.0 1 1 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme zf-C4pol PF14260.1 EIE92178.1 - 0.024 14.6 3.7 0.33 11.0 2.5 2.0 1 1 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta DZR PF12773.2 EIE92178.1 - 0.032 14.0 7.7 0.78 9.6 1.9 2.2 1 1 0 2 2 2 0 Double zinc ribbon A2L_zn_ribbon PF08792.5 EIE92178.1 - 0.032 13.6 3.3 14 5.2 0.0 3.1 3 0 0 3 3 3 0 A2L zinc ribbon domain zinc-ribbons_6 PF07191.7 EIE92178.1 - 0.22 11.3 2.0 1.1 9.0 0.5 2.0 2 0 0 2 2 2 0 zinc-ribbons HypA PF01155.14 EIE92178.1 - 0.55 9.9 4.4 2.4 7.8 1.1 2.0 1 1 0 2 2 2 0 Hydrogenase expression/synthesis hypA family RRN7 PF11781.3 EIE92178.1 - 0.76 9.3 7.5 6 6.4 0.3 3.2 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-ribbon_3 PF13248.1 EIE92178.1 - 0.95 8.7 7.4 0.41 9.9 1.6 2.5 1 1 1 2 2 2 0 zinc-ribbon domain Spt4 PF06093.8 EIE92178.1 - 2.1 8.2 4.6 2.8 7.8 0.8 2.1 1 1 1 2 2 2 0 Spt4/RpoE2 zinc finger zinc_ribbon_2 PF13240.1 EIE92178.1 - 8.6 5.9 9.4 3.8 7.1 0.1 2.8 2 1 0 2 2 2 0 zinc-ribbon domain DUF2863 PF11062.3 EIE92179.1 - 0.0071 14.4 1.1 0.012 13.7 0.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2863) BLOC1_2 PF10046.4 EIE92179.1 - 3.6 7.7 15.0 4.3 7.5 5.2 2.5 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SMN PF06003.7 EIE92179.1 - 6.4 5.7 7.1 5.6 5.9 3.9 1.4 1 1 0 1 1 1 0 Survival motor neuron protein (SMN) Ribosomal_L28e PF01778.12 EIE92181.1 - 6.9e-34 116.7 2.2 6.9e-34 116.7 1.5 2.1 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.9 EIE92181.1 - 1e-24 86.5 22.1 1e-24 86.5 15.3 1.6 2 0 0 2 2 2 1 Mak16 protein C-terminal region Exonuc_VII_L PF02601.10 EIE92181.1 - 2.6 7.1 6.3 3.7 6.6 4.3 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Trypan_glycop PF00913.14 EIE92181.1 - 4.9 5.9 7.5 3.4 6.4 1.2 2.0 1 1 1 2 2 2 0 Trypanosome variant surface glycoprotein (A-type) DDE_3 PF13358.1 EIE92182.1 - 1.7e-13 50.5 0.2 1.8e-13 50.4 0.1 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EIE92185.1 - 9.3e-29 100.0 0.0 6.3e-28 97.3 0.0 2.2 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_29 PF13551.1 EIE92185.1 - 2.3e-05 24.4 0.2 0.001 19.1 0.0 2.7 1 1 1 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.1 EIE92185.1 - 0.0025 17.4 0.0 0.0062 16.1 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain DDE_1 PF03184.14 EIE92185.1 - 0.0075 15.4 0.1 0.016 14.3 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.1 EIE92185.1 - 0.026 15.3 2.0 11 6.9 0.1 3.3 3 0 0 3 3 3 0 Homeodomain-like domain rve PF00665.21 EIE92185.1 - 0.075 13.1 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain FliT PF05400.8 EIE92185.1 - 0.14 12.5 0.2 0.14 12.5 0.2 3.1 4 0 0 4 4 4 0 Flagellar protein FliT HTH_Tnp_Tc3_2 PF01498.13 EIE92186.1 - 1.6e-16 60.1 1.6 6.8e-16 58.0 0.3 2.1 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 EIE92186.1 - 1.6e-06 28.2 0.2 1.6e-06 28.2 0.2 1.7 2 0 0 2 2 2 1 Winged helix-turn helix HTH_38 PF13936.1 EIE92186.1 - 2.8e-06 26.7 0.0 1.1e-05 24.9 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_32 PF13565.1 EIE92186.1 - 4e-06 27.5 1.8 0.0052 17.5 0.1 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_23 PF13384.1 EIE92186.1 - 1.1e-05 24.8 0.1 0.00089 18.8 0.0 2.7 2 0 0 2 2 2 1 Homeodomain-like domain Sigma70_r4_2 PF08281.7 EIE92186.1 - 0.00017 20.9 0.5 0.0079 15.6 0.0 2.8 3 0 0 3 3 3 1 Sigma-70, region 4 HTH_7 PF02796.10 EIE92186.1 - 0.00021 21.0 0.8 0.036 13.9 0.0 2.9 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase HTH_28 PF13518.1 EIE92186.1 - 0.00026 20.9 0.0 0.0016 18.3 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_21 PF13276.1 EIE92186.1 - 0.00032 20.6 0.0 0.044 13.7 0.0 2.4 2 0 0 2 2 2 1 HTH-like domain LacI PF00356.16 EIE92186.1 - 0.0028 17.2 1.2 0.98 9.0 0.2 2.4 2 0 0 2 2 2 2 Bacterial regulatory proteins, lacI family HTH_Tnp_ISL3 PF13542.1 EIE92186.1 - 0.0069 15.5 0.2 3.1 7.0 0.0 2.5 2 0 0 2 2 2 2 Helix-turn-helix domain of transposase family ISL3 HTH_Tnp_4 PF13613.1 EIE92186.1 - 0.011 15.2 0.5 0.02 14.4 0.0 1.6 2 0 0 2 2 2 0 Helix-turn-helix of DDE superfamily endonuclease CPSase_L_D3 PF02787.14 EIE92186.1 - 0.014 15.1 0.0 0.045 13.5 0.0 1.7 2 0 0 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain DUF2857 PF11198.3 EIE92186.1 - 0.018 14.5 0.0 0.029 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2857) HTH_36 PF13730.1 EIE92186.1 - 0.019 15.0 0.0 1.4 9.1 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain Sigma70_r4 PF04545.11 EIE92186.1 - 0.032 13.5 0.4 0.25 10.6 0.0 2.4 3 0 0 3 3 3 0 Sigma-70, region 4 HTH_17 PF12728.2 EIE92186.1 - 0.034 14.4 0.9 5.1 7.4 0.1 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain UPF0122 PF04297.9 EIE92186.1 - 0.052 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like GcrA PF07750.6 EIE92186.1 - 0.11 12.6 0.1 0.15 12.2 0.1 1.2 1 0 0 1 1 1 0 GcrA cell cycle regulator DUF2642 PF10842.3 EIE92186.1 - 0.13 11.7 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2642) Trp_repressor PF01371.14 EIE92186.1 - 0.14 12.0 0.3 2.4 8.1 0.0 2.1 2 0 0 2 2 2 0 Trp repressor protein DDE_Tnp_IS1595 PF12762.2 EIE92187.1 - 2.9e-06 27.2 0.1 5.3e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 ISXO2-like transposase domain Transposase_21 PF02992.9 EIE92188.1 - 1.3e-19 70.1 0.0 2.6e-19 69.2 0.0 1.5 1 0 0 1 1 1 1 Transposase family tnp2 DUF1258 PF06869.7 EIE92188.1 - 0.012 14.7 0.4 0.021 13.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1258) DUF4218 PF13960.1 EIE92189.1 - 0.0099 15.3 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) LAG1-DNAbind PF09271.6 EIE92190.1 - 0.032 14.7 1.2 0.071 13.5 0.9 1.5 1 0 0 1 1 1 0 LAG1, DNA binding FKBP_N PF01346.13 EIE92190.1 - 0.14 12.2 7.8 0.061 13.3 2.7 2.2 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase YebO PF13974.1 EIE92190.1 - 0.25 11.1 12.0 1 9.1 0.0 2.4 2 0 0 2 2 2 0 YebO-like protein DUF2140 PF09911.4 EIE92190.1 - 0.41 9.7 2.1 0.7 9.0 1.5 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) ATP-synt_E PF05680.7 EIE92190.1 - 0.51 10.3 4.2 2.9 7.9 1.9 2.3 2 0 0 2 2 2 0 ATP synthase E chain TSA PF03249.8 EIE92190.1 - 1.4 7.3 8.1 2 6.8 5.6 1.2 1 0 0 1 1 1 0 Type specific antigen RRF_GI PF12614.3 EIE92191.1 - 0.032 14.0 0.8 0.035 13.9 0.5 1.2 1 0 0 1 1 1 0 Ribosome recycling factor DUF2603 PF10788.4 EIE92191.1 - 0.069 12.8 0.8 0.082 12.6 0.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2603) TPR_MLP1_2 PF07926.7 EIE92192.1 - 1.8e-05 24.4 0.2 2.6e-05 23.9 0.2 1.2 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.7 EIE92192.1 - 0.0071 15.5 1.4 0.01 15.0 1.0 1.2 1 0 0 1 1 1 1 Reovirus sigma C capsid protein DUF972 PF06156.8 EIE92192.1 - 0.0099 16.2 0.1 0.017 15.4 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF972) DivIVA PF05103.8 EIE92192.1 - 0.013 15.5 0.0 0.025 14.6 0.0 1.5 1 0 0 1 1 1 0 DivIVA protein HALZ PF02183.13 EIE92192.1 - 0.039 13.6 0.1 0.095 12.4 0.1 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper Phage_GP20 PF06810.6 EIE92192.1 - 0.085 12.2 0.4 0.13 11.7 0.3 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 DivIC PF04977.10 EIE92192.1 - 0.1 12.1 1.6 0.21 11.1 0.9 1.7 1 1 0 1 1 1 0 Septum formation initiator SlyX PF04102.7 EIE92192.1 - 0.1 12.9 0.2 0.24 11.7 0.1 1.7 1 0 0 1 1 1 0 SlyX DUF3446 PF11928.3 EIE92192.1 - 1.5 9.0 9.9 4.3 7.5 6.9 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) DDE_3 PF13358.1 EIE92193.1 - 5.3e-24 84.6 0.0 1e-23 83.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE92193.1 - 5.2e-12 45.6 0.2 1.5e-11 44.1 0.1 1.9 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.1 EIE92193.1 - 5.9e-07 28.9 0.0 2.8e-05 23.6 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.1 EIE92193.1 - 2.9e-05 23.9 0.0 0.00071 19.5 0.0 2.9 3 0 0 3 3 3 1 Helix-turn-helix domain PAX PF00292.13 EIE92193.1 - 8.2e-05 22.3 0.0 0.00019 21.1 0.0 1.6 1 0 0 1 1 1 1 'Paired box' domain rve PF00665.21 EIE92193.1 - 0.00021 21.3 0.0 0.00047 20.2 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain HTH_Tnp_ISL3 PF13542.1 EIE92193.1 - 0.00035 19.6 0.0 0.0074 15.4 0.0 2.9 3 0 0 3 3 3 1 Helix-turn-helix domain of transposase family ISL3 HTH_11 PF08279.7 EIE92193.1 - 0.00094 18.7 0.1 0.017 14.7 0.0 2.3 2 0 0 2 2 2 1 HTH domain DDE_Tnp_ISAZ013 PF07592.6 EIE92193.1 - 0.001 17.8 0.2 0.044 12.5 0.0 2.2 2 0 0 2 2 2 1 Rhodopirellula transposase DDE domain HTH_29 PF13551.1 EIE92193.1 - 0.0015 18.6 0.0 0.0056 16.8 0.0 2.0 1 1 0 1 1 1 1 Winged helix-turn helix Trp_repressor PF01371.14 EIE92193.1 - 0.0048 16.7 0.0 0.014 15.2 0.0 1.7 1 0 0 1 1 1 1 Trp repressor protein HTH_7 PF02796.10 EIE92193.1 - 0.013 15.3 0.5 0.59 10.0 0.0 2.8 3 0 0 3 3 2 0 Helix-turn-helix domain of resolvase CENP-B_N PF04218.8 EIE92193.1 - 0.056 12.8 0.1 0.4 10.1 0.1 2.3 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain COX16 PF14138.1 EIE92193.1 - 0.066 13.3 0.0 0.2 11.8 0.0 1.8 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 HTH_26 PF13443.1 EIE92193.1 - 0.068 13.3 0.0 0.99 9.6 0.0 2.7 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain UPF0258 PF06789.7 EIE92193.1 - 0.082 12.9 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0258) GerE PF00196.14 EIE92193.1 - 0.091 12.0 1.0 0.18 11.1 0.1 1.9 3 0 0 3 3 3 0 Bacterial regulatory proteins, luxR family DDE_3 PF13358.1 EIE92194.1 - 4e-16 59.0 0.0 8.4e-16 58.0 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease NUDIX_4 PF14815.1 EIE92194.1 - 0.012 14.9 0.3 0.018 14.4 0.2 1.3 1 0 0 1 1 1 0 NUDIX domain DDE_3 PF13358.1 EIE92196.1 - 1.8e-09 37.5 0.6 1.5e-05 24.7 0.4 2.7 2 1 1 3 3 3 2 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE92196.1 - 1.5e-08 34.5 0.9 2.4e-08 33.9 0.6 1.4 1 0 0 1 1 1 1 Transposase HTH_38 PF13936.1 EIE92197.1 - 0.00011 21.6 0.0 0.00019 20.9 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.1 EIE92197.1 - 0.00049 19.6 0.3 0.0011 18.4 0.1 1.7 1 1 0 1 1 1 1 Homeodomain-like domain Phage_CII PF05269.6 EIE92197.1 - 0.0084 16.0 0.1 0.021 14.8 0.0 1.7 1 1 1 2 2 2 1 Bacteriophage CII protein Sigma54_DBD PF04552.8 EIE92197.1 - 0.016 14.7 0.1 0.033 13.7 0.1 1.5 1 1 1 2 2 2 0 Sigma-54, DNA binding domain HTH_28 PF13518.1 EIE92197.1 - 0.021 14.8 0.2 0.037 14.0 0.0 1.6 2 0 0 2 2 1 0 Helix-turn-helix domain GcrA PF07750.6 EIE92197.1 - 0.024 14.8 0.1 0.027 14.6 0.0 1.1 1 0 0 1 1 1 0 GcrA cell cycle regulator Terminase_5 PF06056.7 EIE92197.1 - 0.024 14.1 0.1 0.058 12.9 0.0 1.7 1 1 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) CENP-B_N PF04218.8 EIE92197.1 - 0.057 12.8 0.0 0.098 12.0 0.0 1.4 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain TetR_N PF00440.18 EIE92197.1 - 0.063 12.9 0.1 0.1 12.2 0.1 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family HTH_Tnp_4 PF13613.1 EIE92197.1 - 0.064 12.8 0.2 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease Fe_dep_repress PF01325.14 EIE92197.1 - 0.066 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain LacI PF00356.16 EIE92197.1 - 0.068 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family HTH_3 PF01381.17 EIE92197.1 - 0.073 12.9 0.1 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix Rhabdo_ncap PF00945.13 EIE92197.1 - 0.077 11.5 0.0 0.095 11.2 0.0 1.1 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Sigma70_r4_2 PF08281.7 EIE92197.1 - 0.08 12.4 0.1 0.14 11.5 0.1 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 MarR PF01047.17 EIE92197.1 - 0.09 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 MarR family HTH_5 PF01022.15 EIE92197.1 - 0.11 12.2 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_29 PF13551.1 EIE92197.1 - 0.11 12.6 0.1 0.21 11.7 0.1 1.6 1 1 0 1 1 1 0 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.13 EIE92197.1 - 0.2 11.7 1.8 1.7 8.7 0.2 2.2 2 0 0 2 2 2 0 Transposase DDE_Tnp_IS1595 PF12762.2 EIE92199.1 - 1.9e-07 31.0 0.1 4.7e-07 29.7 0.1 1.6 1 0 0 1 1 1 1 ISXO2-like transposase domain DDE_3 PF13358.1 EIE92200.1 - 2e-13 50.2 0.0 3.1e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Ku_PK_bind PF08785.6 EIE92200.1 - 0.0044 16.9 0.0 0.008 16.0 0.0 1.5 1 0 0 1 1 1 1 Ku C terminal domain like rve PF00665.21 EIE92200.1 - 0.049 13.7 0.0 0.075 13.1 0.0 1.3 1 0 0 1 1 1 0 Integrase core domain TC1 PF15063.1 EIE92200.1 - 0.12 11.8 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Thyroid cancer protein 1 DDE_3 PF13358.1 EIE92202.1 - 4e-12 46.1 0.2 5.1e-12 45.7 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE92202.1 - 0.098 12.7 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Integrase core domain RVP PF00077.15 EIE92203.1 - 1.5e-07 31.2 0.1 5.2e-07 29.5 0.1 2.0 1 0 0 1 1 1 1 Retroviral aspartyl protease HTH_Tnp_Tc3_2 PF01498.13 EIE92203.1 - 4.2e-06 26.7 0.1 1.6e-05 24.8 0.0 2.0 1 0 0 1 1 1 1 Transposase Asp_protease_2 PF13650.1 EIE92203.1 - 2.1e-05 24.9 0.6 6.2e-05 23.4 0.1 2.0 2 0 0 2 2 2 1 Aspartyl protease rve PF00665.21 EIE92204.1 - 2.4e-20 72.8 0.0 8e-20 71.1 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE92204.1 - 3.9e-11 42.7 0.3 8.5e-11 41.6 0.2 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE92204.1 - 2e-10 40.1 0.4 5.3e-10 38.8 0.3 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RRF_GI PF12614.3 EIE92205.1 - 0.076 12.8 2.1 0.097 12.4 1.4 1.3 1 1 0 1 1 1 0 Ribosome recycling factor LAG1-DNAbind PF09271.6 EIE92206.1 - 0.028 14.8 1.2 0.063 13.7 0.9 1.6 1 0 0 1 1 1 0 LAG1, DNA binding FKBP_N PF01346.13 EIE92206.1 - 0.12 12.4 7.8 0.055 13.5 2.7 2.2 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase YebO PF13974.1 EIE92206.1 - 0.21 11.4 12.0 0.94 9.3 0.0 2.4 2 0 0 2 2 2 0 YebO-like protein DUF2140 PF09911.4 EIE92206.1 - 0.37 9.9 2.1 0.64 9.1 1.5 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) ATP-synt_E PF05680.7 EIE92206.1 - 0.43 10.5 4.2 2.6 8.0 1.9 2.3 2 0 0 2 2 2 0 ATP synthase E chain TSA PF03249.8 EIE92206.1 - 1.3 7.4 8.2 1.9 6.9 5.7 1.2 1 0 0 1 1 1 0 Type specific antigen Transposase_21 PF02992.9 EIE92207.1 - 8.5e-22 77.3 0.1 1.5e-21 76.5 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DUF1258 PF06869.7 EIE92207.1 - 0.05 12.6 0.0 0.088 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1258) DUF4218 PF13960.1 EIE92207.1 - 0.081 12.3 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) HTH_Tnp_Tc3_2 PF01498.13 EIE92210.1 - 6.6e-12 45.3 0.5 6.6e-12 45.3 0.3 1.8 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.1 EIE92210.1 - 0.00058 19.4 0.1 0.0015 18.1 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.1 EIE92210.1 - 0.00066 19.7 0.3 0.0025 17.9 0.0 1.9 2 0 0 2 2 2 1 Winged helix-turn helix HTH_7 PF02796.10 EIE92210.1 - 0.0052 16.6 0.0 0.012 15.4 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_30 PF13556.1 EIE92210.1 - 0.012 15.2 0.0 0.11 12.1 0.0 2.1 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain HTH_38 PF13936.1 EIE92210.1 - 0.024 14.2 0.0 0.067 12.7 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain rve PF00665.21 EIE92211.1 - 2.5e-20 72.7 0.0 8e-20 71.1 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE92211.1 - 1.6e-10 40.6 0.2 3.8e-10 39.5 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE92211.1 - 2e-10 40.1 0.4 5.3e-10 38.8 0.3 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RRM_1 PF00076.17 EIE92213.1 - 0.13 11.8 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) rve PF00665.21 EIE92214.1 - 1.7e-24 86.1 0.0 5.6e-24 84.5 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE92214.1 - 6.8e-17 61.5 0.0 1.3e-16 60.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE92214.1 - 3.7e-10 39.3 0.6 1.1e-09 37.8 0.4 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 EIE92214.1 - 0.00038 19.7 0.1 0.001 18.4 0.1 1.8 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger UBN2_2 PF14227.1 EIE92214.1 - 0.017 14.6 1.1 0.33 10.5 0.0 2.8 3 0 0 3 3 3 0 gag-polypeptide of LTR copia-type rve_3 PF13683.1 EIE92214.1 - 0.026 14.0 0.0 0.086 12.3 0.0 2.0 1 0 0 1 1 1 0 Integrase core domain UBN2 PF14223.1 EIE92214.1 - 0.062 13.0 0.6 0.16 11.7 0.1 1.9 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 EIE92215.1 - 6e-06 25.9 9.2 0.00072 19.3 0.1 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 EIE92215.1 - 0.0023 17.5 4.4 0.26 10.9 0.2 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.1 EIE92215.1 - 0.0024 17.2 5.1 0.084 12.3 0.0 2.4 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.1 EIE92215.1 - 6.2 6.6 8.1 1.2 8.8 0.2 2.4 1 1 1 2 2 2 0 Zinc knuckle rve PF00665.21 EIE92216.1 - 3.1e-22 78.9 0.0 7.8e-22 77.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 EIE92216.1 - 2.3e-11 43.1 0.2 4.4e-11 42.2 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 EIE92216.1 - 0.0032 16.8 0.1 0.0064 15.8 0.0 1.6 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger YqeY PF09424.5 EIE92217.1 - 2.8e-35 121.2 4.1 3.3e-35 121.0 2.9 1.0 1 0 0 1 1 1 1 Yqey-like protein GatB_Yqey PF02637.13 EIE92217.1 - 0.012 15.3 1.7 0.33 10.6 0.1 2.6 1 1 0 2 2 2 0 GatB domain RPA_interact_M PF14767.1 EIE92217.1 - 0.58 10.9 4.1 1.1 10.0 1.9 2.1 2 0 0 2 2 2 0 Replication protein A interacting middle RabGAP-TBC PF00566.13 EIE92219.1 - 1.6e-42 145.3 4.1 3.4e-42 144.3 2.8 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PAP2 PF01569.16 EIE92220.1 - 1.4e-25 89.4 0.7 1.4e-25 89.4 0.5 1.9 2 0 0 2 2 2 1 PAP2 superfamily DUF3267 PF11667.3 EIE92220.1 - 0.027 14.6 4.3 0.038 14.1 1.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3267) Proteasome PF00227.21 EIE92221.1 - 1.4e-26 92.9 0.0 1.7e-26 92.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Aldo_ket_red PF00248.16 EIE92222.1 - 8.2e-47 159.3 0.0 1e-46 159.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HTH_35 PF13693.1 EIE92222.1 - 0.015 15.0 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Sec5 PF15469.1 EIE92222.1 - 0.035 13.8 0.1 0.41 10.3 0.0 2.1 2 0 0 2 2 2 0 Exocyst complex component Sec5 AA_permease PF00324.16 EIE92223.1 - 4.1e-133 444.2 41.5 5.1e-133 443.9 28.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EIE92223.1 - 2.6e-42 144.8 45.7 3.4e-42 144.4 31.7 1.2 1 0 0 1 1 1 1 Amino acid permease DUF3593 PF12159.3 EIE92223.1 - 0.33 10.7 5.6 1.1 9.0 0.0 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF3593) BC10 PF06726.7 EIE92223.1 - 2.4 8.2 7.3 2.1 8.4 0.1 3.4 3 0 0 3 3 3 0 Bladder cancer-related protein BC10 tRNA-synt_2 PF00152.15 EIE92224.1 - 9.9e-47 159.3 0.0 1.3e-46 158.9 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 EIE92224.1 - 0.008 15.3 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 EIE92224.1 - 0.011 15.2 0.0 1.2 8.6 0.0 2.6 2 1 1 3 3 3 0 tRNA synthetase class II core domain (G, H, P, S and T) HMGL-like PF00682.14 EIE92225.1 - 1e-79 267.5 0.1 1e-79 267.5 0.0 2.4 3 0 0 3 3 3 1 HMGL-like LeuA_dimer PF08502.5 EIE92225.1 - 3e-24 85.3 3.1 5e-24 84.5 2.1 1.4 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain DHHA2 PF02833.9 EIE92225.1 - 0.0099 16.0 0.2 0.021 14.9 0.1 1.5 1 0 0 1 1 1 1 DHHA2 domain RVT_1 PF00078.22 EIE92226.1 - 6e-32 110.7 0.0 1.2e-31 109.7 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Terminase_GpA PF05876.7 EIE92227.1 - 0.027 12.8 0.1 0.039 12.3 0.1 1.2 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) TSC21 PF15217.1 EIE92227.1 - 0.075 12.6 1.7 0.23 11.1 0.2 2.3 1 1 1 3 3 3 0 TSC21 family KGK PF08872.5 EIE92228.1 - 0.00056 20.0 0.3 0.0014 18.7 0.2 1.6 1 0 0 1 1 1 1 KGK domain Syntaxin-6_N PF09177.6 EIE92228.1 - 0.017 15.4 2.0 0.017 15.4 1.4 2.0 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DUF3685 PF12452.3 EIE92228.1 - 0.079 12.1 1.3 0.11 11.6 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3685) Syntaxin PF00804.20 EIE92228.1 - 0.14 12.3 6.6 0.066 13.3 2.0 2.1 2 0 0 2 2 2 0 Syntaxin ATG13 PF10033.4 EIE92229.1 - 9.5e-31 107.0 4.5 5.5e-15 55.4 0.1 2.7 2 1 1 3 3 3 2 Autophagy-related protein 13 MFS_1 PF07690.11 EIE92230.1 - 1.8e-12 46.6 34.6 1.8e-12 46.6 24.0 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily HEAT PF02985.17 EIE92231.1 - 0.0026 17.7 0.0 0.87 9.8 0.0 2.4 2 0 0 2 2 2 2 HEAT repeat Amidohydro_2 PF04909.9 EIE92232.1 - 6.9e-11 42.2 0.1 9.7e-11 41.7 0.1 1.4 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 EIE92232.1 - 4.5e-10 40.0 0.0 6.1e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase TGT PF01702.13 EIE92233.1 - 0.002 17.4 0.0 0.0032 16.7 0.0 1.3 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase BBS2_Mid PF14783.1 EIE92234.1 - 0.00054 19.7 0.0 0.00085 19.0 0.0 1.3 1 1 0 1 1 1 1 Ciliary BBSome complex subunit 2, middle region DUF2414 PF10309.4 EIE92235.1 - 2.9e-12 46.0 0.0 6e-12 45.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) Pkinase PF00069.20 EIE92236.1 - 8.8e-64 215.1 0.1 8.8e-64 215.1 0.1 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE92236.1 - 1.6e-45 155.1 0.1 1.6e-45 155.1 0.1 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.23 EIE92236.1 - 7.6e-21 74.2 0.0 2.1e-20 72.9 0.0 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain PH PF00169.24 EIE92236.1 - 8.1e-13 48.4 0.3 1.9e-12 47.3 0.2 1.7 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.1 EIE92236.1 - 3.1e-06 26.3 1.4 3.3e-06 26.2 0.0 1.8 2 0 0 2 2 2 1 Kinase-like PH_11 PF15413.1 EIE92236.1 - 1.8e-05 24.9 3.6 0.0014 18.8 0.3 3.0 2 1 0 2 2 2 1 Pleckstrin homology domain Kdo PF06293.9 EIE92236.1 - 0.005 15.9 0.4 0.013 14.5 0.2 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIE92236.1 - 0.011 15.5 2.6 0.057 13.1 0.1 2.8 2 1 1 3 3 3 0 Phosphotransferase enzyme family PH_9 PF15410.1 EIE92236.1 - 0.027 14.6 0.1 11 6.1 0.0 2.7 1 1 1 2 2 2 0 Pleckstrin homology domain Peptidase_C58 PF03543.9 EIE92236.1 - 0.034 13.6 2.6 0.071 12.5 1.8 1.6 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen Peptidase_S49_N PF08496.5 EIE92236.1 - 9 6.0 11.5 18 5.1 8.0 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal BTB PF00651.26 EIE92237.1 - 4e-15 55.7 1.3 1.5e-14 53.9 0.1 2.3 2 0 0 2 2 2 1 BTB/POZ domain Kelch_3 PF13415.1 EIE92237.1 - 0.0029 17.7 1.0 0.38 10.9 0.0 2.8 2 1 0 2 2 2 1 Galactose oxidase, central domain Kelch_4 PF13418.1 EIE92237.1 - 0.024 14.4 0.8 1 9.1 0.0 3.0 2 1 0 2 2 2 0 Galactose oxidase, central domain DUF1265 PF06887.9 EIE92237.1 - 0.25 11.0 4.2 3.1 7.5 2.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1265) Pkinase PF00069.20 EIE92238.1 - 8.6e-38 129.9 0.0 8.6e-38 129.9 0.0 2.5 2 1 1 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE92238.1 - 2e-22 79.5 1.7 1.4e-21 76.7 0.0 2.8 2 2 0 2 2 2 1 Protein tyrosine kinase Ycf1 PF05758.7 EIE92238.1 - 1.3e-05 23.2 2.3 1.6e-05 22.9 1.6 1.2 1 0 0 1 1 1 1 Ycf1 PQQ PF01011.16 EIE92238.1 - 0.0073 15.7 0.5 0.055 13.0 0.0 2.7 3 0 0 3 3 3 1 PQQ enzyme repeat Zip PF02535.17 EIE92238.1 - 0.43 9.5 1.2 0.65 8.9 0.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2252 PF10009.4 EIE92238.1 - 0.88 8.3 11.1 1.4 7.7 7.7 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) Neur_chan_memb PF02932.11 EIE92238.1 - 2.1 8.1 8.6 3.8 7.3 6.0 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CAF-1_p150 PF11600.3 EIE92238.1 - 10 5.4 47.3 17 4.6 32.8 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Pkinase PF00069.20 EIE92239.1 - 6.1e-74 248.4 0.0 8.3e-74 248.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE92239.1 - 6.3e-42 143.4 0.0 9.3e-42 142.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE92239.1 - 4e-06 25.9 0.0 3.9e-05 22.7 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EIE92239.1 - 5.2e-06 26.3 0.4 0.0094 15.7 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EIE92239.1 - 0.00061 18.9 1.1 0.0016 17.5 0.8 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EIE92239.1 - 0.013 15.0 0.2 0.037 13.6 0.0 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.4 EIE92239.1 - 0.029 13.7 0.0 0.051 12.9 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DDE_3 PF13358.1 EIE92241.1 - 0.013 15.2 0.1 0.013 15.2 0.1 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease DDE_3 PF13358.1 EIE92242.1 - 2.7e-14 53.1 0.0 4.1e-14 52.5 0.0 1.3 1 1 0 1 1 1 1 DDE superfamily endonuclease 2OG-Fe_Oxy_2 PF10014.4 EIE92242.1 - 0.11 11.8 0.2 0.2 11.0 0.0 1.4 2 0 0 2 2 2 0 2OG-Fe dioxygenase Methyltransf_23 PF13489.1 EIE92243.1 - 0.00078 19.2 0.0 0.0014 18.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EIE92243.1 - 0.00085 18.4 0.0 0.0015 17.6 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.1 EIE92243.1 - 0.011 15.3 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EIE92243.1 - 0.017 14.4 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_18 PF12847.2 EIE92243.1 - 0.02 15.4 0.0 0.032 14.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 EIE92243.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase CMAS PF02353.15 EIE92243.1 - 0.12 11.4 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase bZIP_2 PF07716.10 EIE92244.1 - 2.3e-12 46.5 6.0 2.3e-12 46.5 4.1 2.0 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 EIE92244.1 - 8.3e-11 41.6 10.4 5.8e-10 38.9 6.1 2.1 1 1 1 2 2 2 2 bZIP transcription factor bZIP_Maf PF03131.12 EIE92244.1 - 0.0021 18.3 4.3 0.0029 17.8 2.7 1.4 1 1 0 1 1 1 1 bZIP Maf transcription factor HAP1_N PF04849.8 EIE92244.1 - 0.0078 15.1 2.5 0.0098 14.8 1.7 1.1 1 0 0 1 1 1 1 HAP1 N-terminal conserved region ADIP PF11559.3 EIE92244.1 - 0.013 15.3 4.8 0.02 14.8 3.3 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.4 EIE92244.1 - 0.032 14.1 5.9 0.047 13.5 4.1 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Striatin PF08232.7 EIE92244.1 - 0.046 14.0 1.5 0.046 14.0 1.0 1.9 1 1 1 2 2 2 0 Striatin family Spc7 PF08317.6 EIE92244.1 - 0.1 11.2 2.5 0.13 10.8 1.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DivIC PF04977.10 EIE92244.1 - 0.12 11.8 2.6 0.25 10.8 1.5 1.7 1 1 1 2 2 2 0 Septum formation initiator DUF1465 PF07323.7 EIE92244.1 - 0.13 11.7 5.9 0.24 10.9 1.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1465) FlxA PF14282.1 EIE92244.1 - 0.19 11.6 1.3 0.3 11.0 0.9 1.3 1 0 0 1 1 1 0 FlxA-like protein DUF972 PF06156.8 EIE92244.1 - 0.25 11.6 2.1 0.39 11.0 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF4140 PF13600.1 EIE92244.1 - 1.1 9.7 7.6 0.56 10.6 1.1 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) PspB PF06667.7 EIE92244.1 - 1.2 9.0 3.9 22 5.0 0.9 2.2 2 0 0 2 2 2 0 Phage shock protein B Endosulfine PF04667.12 EIE92246.1 - 1.7e-19 69.5 0.1 1.8e-19 69.4 0.0 1.1 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region DUF4448 PF14610.1 EIE92247.1 - 0.0059 16.1 1.7 0.007 15.8 1.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) LytR_cpsA_psr PF03816.9 EIE92247.1 - 0.015 15.2 0.0 0.016 15.1 0.0 1.2 1 0 0 1 1 1 0 Cell envelope-related transcriptional attenuator domain Aconitase PF00330.15 EIE92248.1 - 4.4e-190 632.1 0.0 5.2e-190 631.8 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EIE92248.1 - 1.2e-45 154.8 0.0 2.7e-45 153.6 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain C2 PF00168.25 EIE92249.1 - 2.7e-10 39.9 0.0 2.7e-10 39.9 0.0 2.5 3 0 0 3 3 3 1 C2 domain CBM_5_12 PF02839.9 EIE92249.1 - 2e-07 30.4 5.0 4.5e-07 29.3 3.5 1.5 1 0 0 1 1 1 1 Carbohydrate binding domain IncA PF04156.9 EIE92249.1 - 3.5e-05 23.4 4.2 5.3e-05 22.9 2.9 1.4 1 0 0 1 1 1 1 IncA protein Utp14 PF04615.8 EIE92249.1 - 0.0046 15.1 44.1 0.006 14.8 30.6 1.1 1 0 0 1 1 1 1 Utp14 protein HemX PF04375.9 EIE92249.1 - 0.037 12.6 1.8 0.069 11.7 1.2 1.4 1 0 0 1 1 1 0 HemX DUF936 PF06075.7 EIE92249.1 - 3.7 6.3 27.3 5.4 5.8 18.9 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) MIP-T3 PF10243.4 EIE92249.1 - 3.9 5.8 59.6 7.8 4.8 41.3 1.4 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 RrnaAD PF00398.15 EIE92250.1 - 6.9e-25 87.5 0.0 8.5e-25 87.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase DnaJ PF00226.26 EIE92251.1 - 2.4e-25 88.0 0.1 2.4e-25 88.0 0.1 2.2 2 0 0 2 2 2 1 DnaJ domain zf-C2H2_jaz PF12171.3 EIE92251.1 - 4.6e-10 39.3 2.5 8.8e-10 38.4 1.8 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EIE92251.1 - 6.6e-08 32.4 1.7 1.1e-07 31.8 1.2 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EIE92251.1 - 0.0071 16.4 1.8 0.015 15.3 0.9 1.8 1 1 0 1 1 1 1 C2H2 type zinc-finger (2 copies) DUF3435 PF11917.3 EIE92251.1 - 1.3 7.6 17.4 0.49 9.0 10.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3435) DIT1_PvcA PF05141.7 EIE92251.1 - 2.5 7.3 8.8 2.2 7.5 5.1 1.6 1 1 1 2 2 2 0 Pyoverdine/dityrosine biosynthesis protein VCBS PF13517.1 EIE92252.1 - 8.1e-24 83.7 10.5 4.3e-07 30.1 0.0 5.1 1 1 4 5 5 5 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 EIE92252.1 - 5.3e-12 45.0 12.7 0.0014 18.2 0.0 6.2 6 0 0 6 6 6 4 FG-GAP repeat TcdB_toxin_midN PF12256.3 EIE92252.1 - 5.8e-05 22.6 4.0 0.41 10.0 0.1 4.8 4 1 1 6 6 6 2 Insecticide toxin TcdB middle/N-terminal region SPW PF03779.9 EIE92252.1 - 0.09 12.1 0.4 0.23 10.8 0.3 1.7 1 0 0 1 1 1 0 SPW repeat DUF1214 PF06742.6 EIE92252.1 - 0.15 12.4 0.3 6.3 7.3 0.0 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF1214) HLH PF00010.21 EIE92255.1 - 5.5e-19 67.6 1.1 5.5e-19 67.6 0.8 2.2 1 1 1 2 2 2 1 Helix-loop-helix DNA-binding domain DUF4085 PF13315.1 EIE92255.1 - 0.00025 20.4 1.3 0.0004 19.7 0.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4085) MerR-DNA-bind PF09278.6 EIE92255.1 - 0.46 10.9 6.4 6 7.3 1.8 2.5 2 0 0 2 2 2 0 MerR, DNA binding NBP1 PF08537.5 EIE92255.1 - 0.51 9.5 8.9 1.9 7.6 6.1 1.8 1 1 0 1 1 1 0 Fungal Nap binding protein NBP1 IncA PF04156.9 EIE92255.1 - 9.3 5.7 13.6 26 4.3 9.4 1.8 1 1 0 1 1 1 0 IncA protein COPIIcoated_ERV PF07970.7 EIE92256.1 - 5.8e-40 137.2 1.0 8.2e-40 136.7 0.7 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EIE92256.1 - 3.4e-21 75.0 0.2 3e-19 68.7 0.1 2.5 1 1 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) ABC_tran PF00005.22 EIE92257.1 - 6.4e-46 156.0 0.3 1.4e-21 77.1 0.0 2.8 3 0 0 3 3 2 2 ABC transporter ABC_tran_2 PF12848.2 EIE92257.1 - 9.7e-19 67.0 6.9 9.7e-19 67.0 4.8 2.7 4 0 0 4 4 1 1 ABC transporter AAA_21 PF13304.1 EIE92257.1 - 2.3e-18 67.1 7.0 0.00071 19.6 0.1 4.3 3 1 1 4 4 4 4 AAA domain SMC_N PF02463.14 EIE92257.1 - 2.2e-10 40.1 0.3 0.02 14.0 0.3 4.4 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EIE92257.1 - 5.9e-09 35.3 3.3 0.00055 19.4 0.0 3.1 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EIE92257.1 - 8.7e-08 33.0 0.2 0.024 15.4 0.0 3.4 2 1 1 3 3 3 2 AAA domain Dynamin_N PF00350.18 EIE92257.1 - 3.3e-07 30.2 0.3 0.0052 16.6 0.0 3.9 2 1 1 3 3 3 1 Dynamin family AAA_23 PF13476.1 EIE92257.1 - 9.3e-07 29.3 5.9 0.039 14.2 0.0 3.7 4 0 0 4 4 3 2 AAA domain AAA_22 PF13401.1 EIE92257.1 - 2.1e-06 27.9 0.1 0.021 14.9 0.0 3.2 2 2 0 2 2 2 2 AAA domain NACHT PF05729.7 EIE92257.1 - 6.4e-06 25.9 0.0 0.021 14.4 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_15 PF13175.1 EIE92257.1 - 8e-06 25.1 1.5 0.65 8.9 0.0 4.3 4 1 0 4 4 4 1 AAA ATPase domain Miro PF08477.8 EIE92257.1 - 8.9e-06 26.2 0.0 0.085 13.3 0.0 3.1 3 0 0 3 3 2 2 Miro-like protein DUF258 PF03193.11 EIE92257.1 - 9.3e-06 24.9 0.0 0.0092 15.1 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 EIE92257.1 - 1.2e-05 25.3 0.1 0.096 12.6 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.1 EIE92257.1 - 2e-05 24.5 0.0 0.28 11.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 EIE92257.1 - 9.2e-05 22.2 0.1 0.055 13.4 0.0 2.9 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.18 EIE92257.1 - 0.0001 22.2 0.1 0.72 9.8 0.0 3.4 2 1 0 2 2 2 2 50S ribosome-binding GTPase MobB PF03205.9 EIE92257.1 - 0.00015 21.5 0.0 0.11 12.1 0.0 2.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 EIE92257.1 - 0.00018 21.8 1.1 0.63 10.3 0.0 3.2 3 1 0 3 3 2 2 AAA domain AAA_25 PF13481.1 EIE92257.1 - 0.0003 20.2 0.0 0.9 8.8 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.1 EIE92257.1 - 0.00039 20.3 0.0 1.3 8.9 0.0 3.9 3 1 0 3 3 3 1 AAA domain RNA_helicase PF00910.17 EIE92257.1 - 0.00053 20.1 0.3 1.1 9.4 0.0 3.1 3 0 0 3 3 3 1 RNA helicase AAA_10 PF12846.2 EIE92257.1 - 0.00058 19.4 1.1 0.59 9.5 0.0 3.2 4 0 0 4 4 4 1 AAA-like domain DUF87 PF01935.12 EIE92257.1 - 0.00074 19.4 0.5 1.5 8.5 0.0 3.2 3 0 0 3 3 3 1 Domain of unknown function DUF87 AAA_28 PF13521.1 EIE92257.1 - 0.00084 19.3 0.0 1.2 9.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EIE92257.1 - 0.0078 16.4 0.0 1.2 9.3 0.0 3.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.13 EIE92257.1 - 0.0096 15.4 0.0 0.87 9.0 0.0 2.8 3 0 0 3 3 2 1 FtsK/SpoIIIE family DAP3 PF10236.4 EIE92257.1 - 0.0097 14.8 1.9 13 4.5 0.0 3.3 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 PduV-EutP PF10662.4 EIE92257.1 - 0.014 14.8 0.3 2.6 7.5 0.0 3.1 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation T2SE PF00437.15 EIE92257.1 - 0.014 14.2 0.0 0.32 9.8 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein ArgK PF03308.11 EIE92257.1 - 0.016 13.9 0.2 3.5 6.3 0.0 2.8 3 0 0 3 3 3 0 ArgK protein Pox_A32 PF04665.7 EIE92257.1 - 0.02 14.2 0.0 5.6 6.1 0.0 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_30 PF13604.1 EIE92257.1 - 0.022 14.3 0.0 1.2 8.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EIE92257.1 - 0.023 13.5 0.0 6.5 5.5 0.0 2.8 2 1 0 2 2 2 0 NB-ARC domain AAA_5 PF07728.9 EIE92257.1 - 0.024 14.3 0.0 5.4 6.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) SRP54 PF00448.17 EIE92257.1 - 0.025 13.9 0.9 5.1 6.4 0.0 2.9 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.7 EIE92257.1 - 0.033 13.2 0.0 0.28 10.2 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin cobW PF02492.14 EIE92257.1 - 0.033 13.6 0.1 6.6 6.1 0.0 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.13 EIE92257.1 - 0.037 13.0 0.0 8.1 5.3 0.0 2.5 2 0 0 2 2 2 0 Septin EIIA-man PF03610.11 EIE92257.1 - 0.04 13.9 1.3 0.14 12.2 0.1 2.2 2 0 0 2 2 2 0 PTS system fructose IIA component DUF948 PF06103.6 EIE92257.1 - 0.062 13.1 0.0 0.21 11.4 0.0 1.9 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) AAA_24 PF13479.1 EIE92257.1 - 0.073 12.6 2.8 1.3 8.5 0.0 3.1 4 0 0 4 4 2 0 AAA domain UPF0079 PF02367.12 EIE92257.1 - 0.078 12.6 0.4 3.8 7.1 0.0 3.4 3 1 1 4 4 4 0 Uncharacterised P-loop hydrolase UPF0079 MutS_V PF00488.16 EIE92257.1 - 0.083 12.2 0.0 8.8 5.6 0.0 2.8 3 0 0 3 3 2 0 MutS domain V Lipocalin_5 PF13924.1 EIE92257.1 - 0.12 12.0 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Lipocalin-like domain ATP_bind_1 PF03029.12 EIE92257.1 - 0.21 11.0 2.4 10 5.5 0.1 2.9 3 1 1 4 4 2 0 Conserved hypothetical ATP binding protein AAA_13 PF13166.1 EIE92257.1 - 0.33 9.3 7.9 3.5 5.9 0.4 3.6 3 1 1 4 4 4 0 AAA domain DUF3987 PF13148.1 EIE92257.1 - 1.7 7.1 5.3 2.8 6.3 0.4 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3987) Gtr1_RagA PF04670.7 EIE92259.1 - 2.2e-68 229.8 0.6 3.5e-68 229.2 0.4 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EIE92259.1 - 0.00024 21.5 0.1 0.00086 19.7 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EIE92259.1 - 0.014 14.6 0.0 0.025 13.7 0.0 1.5 1 0 0 1 1 1 0 ADP-ribosylation factor family ATP_bind_1 PF03029.12 EIE92259.1 - 0.015 14.8 0.1 0.025 14.1 0.1 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.18 EIE92259.1 - 0.023 14.6 0.0 0.14 12.1 0.0 2.1 1 1 0 2 2 2 0 50S ribosome-binding GTPase RCC1 PF00415.13 EIE92260.1 - 1.3e-65 217.3 9.6 2.8e-10 40.2 0.0 7.9 7 2 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EIE92260.1 - 1.4e-33 113.7 33.6 2.5e-08 33.3 0.2 8.2 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat CBM_X PF06204.6 EIE92260.1 - 0.0047 16.3 0.1 31 4.1 0.0 4.3 4 0 0 4 4 4 1 Putative carbohydrate binding domain SIS_2 PF13580.1 EIE92260.1 - 0.13 12.0 0.5 0.91 9.2 0.0 2.4 3 0 0 3 3 3 0 SIS domain DUF3177 PF11375.3 EIE92261.1 - 0.027 13.9 0.5 0.03 13.7 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3177) DUF3975 PF13126.1 EIE92261.1 - 0.15 12.2 2.7 0.27 11.4 1.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3975) DDE_3 PF13358.1 EIE92262.1 - 1.2e-17 64.0 0.1 1.9e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE92262.1 - 1.3e-07 31.6 1.1 2.2e-07 30.8 0.8 1.5 1 0 0 1 1 1 1 Transposase Pkinase PF00069.20 EIE92263.1 - 2.5e-48 164.4 0.0 6.1e-48 163.2 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE92263.1 - 5.5e-16 58.4 0.0 1.1e-15 57.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIE92263.1 - 0.0018 18.0 0.0 0.003 17.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EIE92263.1 - 0.062 12.3 0.0 0.096 11.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family G6PD_C PF02781.11 EIE92264.1 - 4.4e-121 403.2 0.0 6.4e-121 402.7 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 EIE92264.1 - 1.6e-59 201.2 0.6 2.6e-59 200.5 0.4 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Mitofilin PF09731.4 EIE92265.1 - 1.6e-94 317.6 45.4 3.4e-92 309.9 31.5 2.1 1 1 0 1 1 1 1 Mitochondrial inner membrane protein DUF217 PF02697.9 EIE92265.1 - 1.7 8.9 7.0 2.9 8.1 0.1 4.1 3 1 1 4 4 4 0 Uncharacterized ACR, COG1753 Mt_ATP-synt_B PF05405.9 EIE92266.1 - 1.2e-44 151.6 6.3 1.6e-44 151.2 4.4 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF1539 PF07560.6 EIE92266.1 - 0.013 15.3 0.8 0.017 14.9 0.6 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1539) TrbI_Ftype PF09677.5 EIE92266.1 - 0.078 12.8 0.7 0.19 11.5 0.2 1.9 2 1 0 2 2 2 0 Type-F conjugative transfer system protein (TrbI_Ftype) Hepatitis_core PF00906.15 EIE92266.1 - 0.088 12.4 0.1 0.19 11.3 0.1 1.5 1 0 0 1 1 1 0 Hepatitis core antigen SMAP PF15477.1 EIE92267.1 - 1.1e-18 67.2 5.7 1.1e-18 67.2 3.9 3.7 2 1 0 2 2 1 1 Small acidic protein family MIP-T3 PF10243.4 EIE92267.1 - 0.0043 15.5 46.8 0.0043 15.5 32.4 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 DUF2413 PF10310.4 EIE92267.1 - 0.034 12.9 32.1 0.035 12.9 22.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DUF1777 PF08648.7 EIE92267.1 - 0.27 10.9 29.5 0.37 10.5 20.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) SAPS PF04499.10 EIE92267.1 - 0.61 8.6 20.0 0.61 8.6 13.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF2457 PF10446.4 EIE92267.1 - 0.73 8.5 29.2 0.87 8.2 20.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF2217 PF10265.4 EIE92267.1 - 1.3 7.7 14.4 1.4 7.6 10.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DUF572 PF04502.8 EIE92267.1 - 1.4 8.0 34.6 1.6 7.8 24.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) AF-4 PF05110.8 EIE92267.1 - 1.6 6.5 32.0 1.6 6.5 22.2 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF4603 PF15376.1 EIE92267.1 - 1.7 5.7 27.4 1.7 5.7 19.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) CDC27 PF09507.5 EIE92267.1 - 2 7.5 46.0 2.3 7.3 31.9 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 AAA_21 PF13304.1 EIE92267.1 - 2.8 7.8 9.9 3.9 7.3 6.9 1.3 1 0 0 1 1 1 0 AAA domain Transformer PF06495.6 EIE92267.1 - 3.2 7.5 9.9 4.5 7.1 6.9 1.2 1 0 0 1 1 1 0 Fruit fly transformer protein Peptidase_S64 PF08192.6 EIE92267.1 - 3.8 5.7 20.9 4.3 5.5 14.5 1.0 1 0 0 1 1 1 0 Peptidase family S64 Prog_receptor PF02161.10 EIE92267.1 - 4 6.1 11.6 5.2 5.7 8.0 1.1 1 0 0 1 1 1 0 Progesterone receptor Ycf1 PF05758.7 EIE92267.1 - 4.1 4.9 34.3 5 4.7 23.8 1.1 1 0 0 1 1 1 0 Ycf1 Mitofilin PF09731.4 EIE92267.1 - 4.2 5.8 31.3 5.2 5.6 21.7 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Ank_2 PF12796.2 EIE92268.1 - 1.1e-16 60.9 4.5 4.2e-11 43.0 0.3 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EIE92268.1 - 6.6e-10 38.2 0.3 0.0082 15.9 0.2 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 EIE92268.1 - 6.8e-08 32.8 0.1 0.0074 16.7 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EIE92268.1 - 7.6e-08 32.3 0.2 0.00013 22.1 0.1 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIE92268.1 - 9.2e-06 25.4 0.1 0.077 13.2 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat DUF3381 PF11861.3 EIE92268.1 - 0.015 14.8 0.1 0.037 13.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) WD40 PF00400.27 EIE92269.1 - 1.4e-55 183.2 22.0 1.3e-11 43.8 0.2 8.1 8 0 0 8 8 8 8 WD domain, G-beta repeat eIF2A PF08662.6 EIE92269.1 - 2.2e-07 30.7 0.2 0.0092 15.7 0.0 2.5 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EIE92269.1 - 2.5e-07 29.2 2.3 0.0033 15.6 0.1 3.0 2 1 1 3 3 3 2 Nucleoporin Nup120/160 PQQ_3 PF13570.1 EIE92269.1 - 0.022 15.0 0.3 12 6.3 0.0 4.1 3 1 0 3 3 3 0 PQQ-like domain DUF1513 PF07433.6 EIE92269.1 - 0.025 13.4 0.2 14 4.4 0.0 3.8 1 1 3 4 4 4 0 Protein of unknown function (DUF1513) Pkinase PF00069.20 EIE92270.1 - 6e-38 130.4 0.0 9.3e-38 129.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE92270.1 - 3.6e-12 45.9 0.0 5.2e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIE92270.1 - 2e-05 24.4 0.0 0.0058 16.3 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Complex1_LYR PF05347.10 EIE92271.1 - 1.9e-09 37.1 0.0 2.8e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EIE92271.1 - 1.1e-08 35.0 0.0 1.8e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 EIE92271.1 - 3e-06 27.6 0.0 3.5e-06 27.4 0.0 1.3 1 1 0 1 1 1 1 Complex1_LYR-like IL8 PF00048.15 EIE92273.1 - 0.0031 17.4 0.3 0.0036 17.2 0.2 1.1 1 0 0 1 1 1 1 Small cytokines (intecrine/chemokine), interleukin-8 like Ca_chan_IQ PF08763.6 EIE92273.1 - 0.022 13.9 0.2 0.041 13.1 0.1 1.5 1 0 0 1 1 1 0 Voltage gated calcium channel IQ domain WD40 PF00400.27 EIE92274.1 - 9.1e-24 82.4 11.6 4.6e-08 32.6 0.0 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat Rax2 PF12768.2 EIE92274.1 - 1e-05 24.8 1.6 5.5e-05 22.5 0.0 2.5 3 0 0 3 3 3 1 Cortical protein marker for cell polarity eIF2A PF08662.6 EIE92274.1 - 0.099 12.3 1.5 1.9 8.1 0.0 3.2 3 1 0 4 4 4 0 Eukaryotic translation initiation factor eIF2A VPS28 PF03997.7 EIE92275.1 - 8.4e-47 159.2 0.1 9.8e-47 159.0 0.0 1.0 1 0 0 1 1 1 1 VPS28 protein adh_short PF00106.20 EIE92277.1 - 5.3e-23 81.7 0.1 7.3e-23 81.3 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIE92277.1 - 6.1e-13 49.0 0.1 8.6e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIE92277.1 - 2.4e-10 40.3 0.0 3.2e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EIE92277.1 - 0.0022 17.7 0.1 0.006 16.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 EIE92277.1 - 0.0045 17.0 0.2 0.017 15.1 0.2 1.8 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EIE92277.1 - 0.023 14.1 0.2 0.034 13.5 0.1 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EIE92277.1 - 0.076 11.6 0.2 0.1 11.2 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF1776 PF08643.5 EIE92277.1 - 0.079 12.0 0.1 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) 3HCDH_N PF02737.13 EIE92277.1 - 0.091 12.4 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CRAL_TRIO PF00650.15 EIE92278.1 - 3.4e-14 52.6 0.0 7.5e-14 51.5 0.0 1.6 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EIE92278.1 - 1.4e-09 37.9 0.1 2.2e-09 37.2 0.1 1.3 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain ATP-synt_ab PF00006.20 EIE92279.1 - 1.3e-69 233.9 0.0 2.1e-69 233.3 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EIE92279.1 - 6.2e-26 91.0 0.0 1.6e-25 89.7 0.0 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EIE92279.1 - 1.9e-20 72.8 0.6 1.9e-20 72.8 0.4 1.9 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EIE92279.1 - 2.8e-05 23.9 0.3 0.00011 22.0 0.2 2.0 1 1 0 1 1 1 1 HAS barrel domain OrfB_Zn_ribbon PF07282.6 EIE92280.1 - 6.5e-08 32.1 3.9 1.7e-07 30.7 2.7 1.8 1 0 0 1 1 1 1 Putative transposase DNA-binding domain Stanniocalcin PF03298.8 EIE92280.1 - 0.0031 16.5 4.6 0.0083 15.1 0.1 2.6 2 0 0 2 2 2 1 Stanniocalcin family DUF2340 PF10209.4 EIE92280.1 - 0.057 13.5 2.6 7.9 6.6 0.1 3.6 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2340) DUF4298 PF14131.1 EIE92280.1 - 1.4 8.8 10.0 2.6 7.9 0.3 4.1 3 1 1 4 4 4 0 Domain of unknown function (DUF4298) zf-RVT PF13966.1 EIE92281.1 - 1.8e-06 28.1 0.7 1.8e-06 28.1 0.5 1.8 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase Proteasome PF00227.21 EIE92282.1 - 9.5e-52 175.0 0.7 1.1e-51 174.8 0.5 1.0 1 0 0 1 1 1 1 Proteasome subunit WD40 PF00400.27 EIE92283.1 - 6.1e-08 32.2 5.1 3.8e-07 29.7 0.0 4.2 6 0 0 6 6 6 1 WD domain, G-beta repeat AT_hook PF02178.14 EIE92283.1 - 0.51 10.1 35.4 0.038 13.6 2.0 3.6 2 1 1 3 3 3 0 AT hook motif Macoilin PF09726.4 EIE92283.1 - 0.63 8.2 8.2 0.77 7.9 5.7 1.2 1 0 0 1 1 1 0 Transmembrane protein STN PF07660.9 EIE92284.1 - 0.039 13.5 0.8 0.079 12.5 0.6 1.5 1 0 0 1 1 1 0 Secretin and TonB N terminus short domain RVT_1 PF00078.22 EIE92285.1 - 0.033 13.5 0.0 0.059 12.7 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) UDG PF03167.14 EIE92285.1 - 0.11 11.9 0.0 0.25 10.8 0.0 1.6 1 0 0 1 1 1 0 Uracil DNA glycosylase superfamily rve PF00665.21 EIE92286.1 - 3.1e-11 43.4 0.0 3.4e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 EIE92286.1 - 0.017 14.5 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 Integrase core domain CorA PF01544.13 EIE92287.1 - 0.0031 16.5 2.1 0.005 15.9 1.5 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein IncA PF04156.9 EIE92287.1 - 0.01 15.4 3.3 0.015 14.9 2.3 1.3 1 0 0 1 1 1 0 IncA protein FliD_C PF07195.7 EIE92287.1 - 0.039 13.2 0.3 0.039 13.2 0.2 2.1 1 1 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus DUF4284 PF14112.1 EIE92287.1 - 0.17 12.3 5.0 0.14 12.6 1.7 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4284) Retrotrans_gag PF03732.12 EIE92287.1 - 0.43 10.6 4.6 1.2 9.2 0.1 2.9 3 1 0 3 3 3 0 Retrotransposon gag protein Golgin_A5 PF09787.4 EIE92287.1 - 3.9 5.8 13.7 0.19 10.1 5.7 1.7 2 1 0 2 2 2 0 Golgin subfamily A member 5 DUF1040 PF06288.8 EIE92288.1 - 0.059 13.6 3.0 1.6 8.9 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1040) DUF1917 PF08939.5 EIE92288.1 - 0.085 12.5 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1917) DUF2501 PF10696.4 EIE92288.1 - 0.1 12.6 0.1 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2501) rve PF00665.21 EIE92289.1 - 6.5e-27 94.0 0.0 1.3e-26 93.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 EIE92289.1 - 2.4e-05 23.7 0.0 6.2e-05 22.4 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.5 EIE92289.1 - 0.0012 18.2 0.4 0.0032 16.8 0.3 1.7 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger RVT_1 PF00078.22 EIE92290.1 - 0.0023 17.3 0.1 0.0038 16.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease PF09668.5 EIE92291.1 - 8.5e-11 41.4 0.0 1.7e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 EIE92291.1 - 8.8e-09 35.7 0.0 1.8e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 EIE92291.1 - 5.9e-07 29.3 0.0 1.8e-06 27.8 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.6 EIE92291.1 - 2e-06 27.7 0.0 3.8e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EIE92291.1 - 1.9e-05 24.3 0.1 3.5e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease rve PF00665.21 EIE92292.1 - 8e-20 71.1 0.0 8e-19 67.9 0.0 2.8 3 0 0 3 3 3 1 Integrase core domain RVT_1 PF00078.22 EIE92292.1 - 4.6e-07 29.4 0.6 1.2e-06 27.9 0.1 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP PF00077.15 EIE92292.1 - 0.0041 16.9 0.1 0.016 15.1 0.0 2.1 2 0 0 2 2 2 1 Retroviral aspartyl protease DUF2361 PF10153.4 EIE92292.1 - 0.0081 16.3 0.6 0.0081 16.3 0.4 2.3 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2361) Asp_protease_2 PF13650.1 EIE92292.1 - 0.1 13.1 0.3 0.29 11.6 0.0 2.0 2 0 0 2 2 2 0 Aspartyl protease Integrase_Zn PF02022.14 EIE92292.1 - 6.4 6.3 7.3 0.16 11.3 0.3 2.0 2 0 0 2 2 2 0 Integrase Zinc binding domain RVT_1 PF00078.22 EIE92293.1 - 1.6e-30 106.0 0.1 3.5e-30 104.9 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 EIE92293.1 - 2.3e-05 24.7 0.0 5.5e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 EIE92293.1 - 2.7e-05 23.9 0.0 8.7e-05 22.3 0.0 1.9 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.6 EIE92293.1 - 0.00019 21.3 0.0 0.00035 20.4 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.12 EIE92293.1 - 0.00055 19.9 0.3 0.017 15.1 0.0 3.1 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.18 EIE92293.1 - 0.00085 19.1 2.3 0.0021 17.9 1.6 1.7 1 0 0 1 1 1 1 Zinc knuckle gag-asp_proteas PF13975.1 EIE92293.1 - 0.019 14.7 0.0 0.079 12.7 0.0 2.0 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease rve PF00665.21 EIE92294.1 - 4.4e-25 88.1 0.0 7.6e-25 87.3 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 EIE92294.1 - 8.5e-11 41.3 1.1 1.9e-10 40.2 0.8 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve_3 PF13683.1 EIE92294.1 - 0.0059 16.1 0.0 0.016 14.6 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain DDE_3 PF13358.1 EIE92296.1 - 3.6e-12 46.2 0.2 4.7e-12 45.8 0.2 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE92297.1 - 4.6e-12 46.1 0.0 1.6e-11 44.3 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.1 EIE92297.1 - 0.0028 17.1 0.3 0.0077 15.7 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain DDE_Tnp_IS1595 PF12762.2 EIE92298.1 - 1.2e-05 25.2 0.1 2.1e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 ISXO2-like transposase domain Retrotrans_gag PF03732.12 EIE92299.1 - 9.4e-05 22.4 0.5 0.0002 21.3 0.3 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein UBN2_2 PF14227.1 EIE92299.1 - 0.0057 16.2 0.0 0.018 14.6 0.0 1.8 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EIE92299.1 - 0.0067 16.2 1.2 0.01 15.5 0.0 1.9 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type WD40 PF00400.27 EIE92302.1 - 1.9e-14 52.8 3.9 0.35 10.8 0.1 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat Proteasome PF00227.21 EIE92303.1 - 5e-44 149.8 0.1 6.1e-44 149.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EIE92303.1 - 3.1e-13 48.7 0.1 5.4e-13 47.9 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature CRISPR_Cse1 PF09481.5 EIE92303.1 - 0.06 12.0 0.0 0.074 11.7 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated protein Cse1 (CRISPR_cse1) DUF1771 PF08590.5 EIE92304.1 - 2.8e-20 72.0 9.0 8.2e-20 70.5 6.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.16 EIE92304.1 - 2.1e-14 53.4 0.1 6.3e-14 51.9 0.0 1.9 2 0 0 2 2 2 1 Smr domain DUF1943 PF09172.6 EIE92304.1 - 0.14 11.0 4.1 0.17 10.7 2.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) Nucleoporin_FG PF13634.1 EIE92305.1 - 8.4e-09 35.6 176.2 0.017 15.3 32.2 4.6 1 1 3 4 4 4 3 Nucleoporin FG repeat region Radical_SAM PF04055.16 EIE92306.1 - 1.4e-12 48.0 0.0 2.2e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.1 EIE92306.1 - 3.9e-06 26.8 0.0 6.4e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.1 EIE92306.1 - 0.013 15.6 0.0 0.022 14.8 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S single cluster domain zf-C2H2 PF00096.21 EIE92307.1 - 1.7e-12 46.9 17.1 2e-07 30.9 0.7 2.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIE92307.1 - 7.8e-09 35.2 15.8 5.1e-05 23.3 0.3 2.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EIE92307.1 - 1.8e-07 31.1 19.6 4.7e-07 29.7 3.3 3.7 3 1 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.2 EIE92307.1 - 0.0027 17.8 5.0 1.2 9.4 1.8 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-BED PF02892.10 EIE92307.1 - 0.0072 16.0 6.4 0.24 11.1 0.2 2.4 2 0 0 2 2 2 2 BED zinc finger zf-C2H2_jaz PF12171.3 EIE92307.1 - 0.036 14.2 7.0 0.47 10.6 0.2 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EIE92307.1 - 0.27 11.3 6.8 0.34 11.0 1.9 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-TRAF PF02176.13 EIE92307.1 - 0.4 11.1 4.4 1.6 9.1 0.3 2.2 1 1 1 2 2 2 0 TRAF-type zinc finger zf-C2H2_6 PF13912.1 EIE92307.1 - 3.4 7.6 7.1 1.6 8.7 1.1 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger SAM_1 PF00536.25 EIE92308.1 - 3.9e-10 39.7 0.1 4.6e-10 39.5 0.1 1.1 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EIE92308.1 - 2.1e-07 30.6 0.1 2.4e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) NCD1 PF04904.8 EIE92308.1 - 0.00018 21.1 0.2 0.00032 20.3 0.1 1.4 1 1 0 1 1 1 1 NAB conserved region 1 (NCD1) DUF3680 PF12441.3 EIE92308.1 - 0.0041 16.9 0.1 0.0066 16.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3680) WD40 PF00400.27 EIE92309.1 - 1.9e-57 189.2 9.9 4.1e-09 35.9 0.1 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 EIE92309.1 - 5.4e-11 41.3 9.2 0.0056 14.8 0.1 5.0 1 1 3 4 4 4 4 Nucleoporin Nup120/160 PQQ_2 PF13360.1 EIE92309.1 - 0.0027 17.2 0.0 0.17 11.3 0.0 2.3 1 1 1 2 2 2 2 PQQ-like domain Hira PF07569.6 EIE92309.1 - 0.11 11.7 0.1 7.7 5.6 0.0 2.6 3 0 0 3 3 3 0 TUP1-like enhancer of split eIF2A PF08662.6 EIE92309.1 - 0.12 12.0 0.0 14 5.2 0.0 2.2 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A CENP-S PF15630.1 EIE92310.1 - 1.5e-08 34.7 0.1 6.2e-08 32.7 0.1 1.8 1 1 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 EIE92310.1 - 0.0086 15.3 0.0 0.0095 15.2 0.0 1.0 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T TAF PF02969.12 EIE92310.1 - 0.14 12.1 0.2 0.31 11.0 0.1 1.6 1 1 0 1 1 1 0 TATA box binding protein associated factor (TAF) Vac_ImportDeg PF09783.4 EIE92311.1 - 7.7e-59 198.1 5.8 1e-58 197.7 4.0 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein Asp PF00026.18 EIE92312.1 - 7.1e-91 304.7 4.4 8.3e-91 304.5 3.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIE92312.1 - 2.9e-08 33.8 1.0 1.8e-05 24.7 0.2 3.3 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EIE92312.1 - 0.00034 21.0 0.8 0.15 12.5 0.1 2.9 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 EIE92312.1 - 0.0012 18.4 0.2 0.087 12.3 0.2 2.8 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal AAA PF00004.24 EIE92313.1 - 1.1e-43 148.5 0.0 1.8e-43 147.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EIE92313.1 - 2.4e-07 30.8 0.0 1.4e-06 28.3 0.0 2.2 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EIE92313.1 - 7.1e-07 29.0 0.1 1.7e-05 24.5 0.1 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EIE92313.1 - 2.8e-06 26.5 0.0 5.2e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EIE92313.1 - 3.6e-06 27.1 0.1 0.00014 21.9 0.0 2.5 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 EIE92313.1 - 3.7e-06 27.1 0.1 0.0012 18.9 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 EIE92313.1 - 0.00023 20.8 0.1 0.0005 19.7 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EIE92313.1 - 0.00027 21.7 0.8 0.00089 20.0 0.1 2.3 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.8 EIE92313.1 - 0.00033 19.6 0.0 0.00086 18.2 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 EIE92313.1 - 0.0011 18.8 0.0 0.004 17.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 EIE92313.1 - 0.0011 18.5 0.3 0.0022 17.5 0.2 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EIE92313.1 - 0.0014 17.8 0.0 0.0033 16.5 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 EIE92313.1 - 0.0017 18.2 0.0 0.0033 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 EIE92313.1 - 0.0027 16.4 0.0 0.0047 15.6 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus IstB_IS21 PF01695.12 EIE92313.1 - 0.003 17.0 0.1 0.0057 16.0 0.1 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.1 EIE92313.1 - 0.0045 17.3 0.0 0.014 15.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EIE92313.1 - 0.0059 16.7 0.0 0.012 15.8 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_3 PF07726.6 EIE92313.1 - 0.0083 15.7 0.0 0.017 14.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EIE92313.1 - 0.0088 15.1 0.1 0.027 13.5 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin AAA_25 PF13481.1 EIE92313.1 - 0.013 14.9 0.3 0.066 12.6 0.2 2.0 1 1 1 2 2 2 0 AAA domain Sigma54_activat PF00158.21 EIE92313.1 - 0.014 14.8 0.1 0.053 12.9 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_28 PF13521.1 EIE92313.1 - 0.018 14.9 0.0 0.038 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EIE92313.1 - 0.03 13.9 0.1 0.08 12.5 0.0 1.7 2 0 0 2 2 2 0 NACHT domain PhoH PF02562.11 EIE92313.1 - 0.032 13.4 0.0 0.055 12.6 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein KaiC PF06745.8 EIE92313.1 - 0.047 12.7 0.3 0.22 10.6 0.0 2.2 2 1 1 3 3 3 0 KaiC Parvo_NS1 PF01057.12 EIE92313.1 - 0.049 12.5 0.0 0.082 11.7 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 UPF0079 PF02367.12 EIE92313.1 - 0.051 13.2 0.0 0.092 12.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 ResIII PF04851.10 EIE92313.1 - 0.068 12.9 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Arch_ATPase PF01637.13 EIE92313.1 - 0.072 12.7 0.0 0.27 10.9 0.0 1.9 1 1 0 1 1 1 0 Archaeal ATPase Sigma54_activ_2 PF14532.1 EIE92313.1 - 0.11 12.5 0.0 0.27 11.2 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_30 PF13604.1 EIE92313.1 - 0.13 11.8 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain BRE1 PF08647.6 EIE92315.1 - 0.019 14.8 0.5 0.019 14.8 0.3 1.8 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF2524 PF10732.4 EIE92315.1 - 1.6 8.9 5.5 1.6 8.8 2.1 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2524) Chitin_synth_2 PF03142.10 EIE92316.1 - 1.9e-244 811.9 0.4 2.7e-244 811.4 0.3 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 EIE92316.1 - 6.5e-113 378.1 3.2 1.1e-112 377.3 2.2 1.4 1 0 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.23 EIE92316.1 - 2.4e-18 65.7 0.1 1.4e-13 50.4 0.1 3.0 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.1 EIE92316.1 - 2.7e-16 60.0 0.0 1.5e-13 51.1 0.0 2.9 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EIE92316.1 - 5.2e-14 52.4 1.3 5.2e-14 52.4 0.9 2.3 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.1 EIE92316.1 - 0.00016 21.0 0.0 0.0057 15.9 0.0 2.6 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EIE92316.1 - 0.00032 20.4 0.0 0.013 15.1 0.0 2.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 SMC_N PF02463.14 EIE92316.1 - 0.23 10.6 0.0 0.62 9.2 0.0 1.6 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain DPBB_1 PF03330.13 EIE92317.1 - 3.1e-11 43.0 0.1 4.2e-11 42.7 0.1 1.3 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EIE92317.1 - 0.00013 21.6 0.3 0.00015 21.4 0.2 1.1 1 0 0 1 1 1 1 Barwin family DPBB_1 PF03330.13 EIE92318.1 - 3.7e-05 23.6 0.1 6.8e-05 22.8 0.1 1.5 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EIE92318.1 - 0.0002 21.0 0.1 0.00023 20.8 0.0 1.3 1 1 0 1 1 1 1 Barwin family zf-CCHC PF00098.18 EIE92319.1 - 0.023 14.5 18.7 0.027 14.3 0.9 3.2 3 0 0 3 3 3 0 Zinc knuckle DnaJ_CXXCXGXG PF00684.14 EIE92319.1 - 0.55 10.3 7.5 6.3 6.9 0.1 2.6 2 0 0 2 2 2 0 DnaJ central domain RVT_1 PF00078.22 EIE92320.1 - 2.6e-25 89.0 0.0 4.5e-25 88.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GlutR_dimer PF00745.15 EIE92320.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, dimerisation domain zf-RVT PF13966.1 EIE92321.1 - 0.00045 20.4 0.2 0.00093 19.4 0.1 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase ATP11 PF06644.6 EIE92322.1 - 1.9e-36 125.9 1.8 9.6e-29 100.6 0.0 2.5 1 1 1 2 2 2 2 ATP11 protein ApbA_C PF08546.6 EIE92322.1 - 9e-30 103.2 0.2 1.5e-29 102.4 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 EIE92322.1 - 8.7e-20 70.6 0.1 1.6e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Ribosomal_S14 PF00253.16 EIE92323.1 - 2.7e-19 68.3 4.0 2.9e-19 68.1 2.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF4428 PF14471.1 EIE92323.1 - 0.065 12.9 0.1 0.084 12.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) DUF1451 PF07295.6 EIE92323.1 - 0.066 12.9 0.2 0.066 12.9 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1451) Ribophorin_I PF04597.9 EIE92324.1 - 5.3e-114 381.0 5.4 6.3e-114 380.8 3.7 1.0 1 0 0 1 1 1 1 Ribophorin I GTP_EFTU PF00009.22 EIE92325.1 - 6.5e-39 133.3 0.1 1e-38 132.6 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 EIE92325.1 - 2.5e-35 120.4 0.3 6.8e-35 118.9 0.2 1.8 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 EIE92325.1 - 7.4e-08 32.4 1.5 7.4e-08 32.4 1.1 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EIE92325.1 - 0.0077 16.1 0.0 0.016 15.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EIE92325.1 - 0.037 13.8 0.0 0.2 11.4 0.0 2.1 2 1 1 3 3 3 0 Dynamin family LMF1 PF06762.9 EIE92327.1 - 0.9 8.2 3.4 0.83 8.3 2.4 1.0 1 0 0 1 1 1 0 Lipase maturation factor Exo_endo_phos_2 PF14529.1 EIE92329.1 - 5.1e-13 48.6 0.0 9.5e-13 47.8 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase HALZ PF02183.13 EIE92330.1 - 0.00069 19.2 1.0 0.0015 18.1 0.4 1.8 1 1 0 1 1 1 1 Homeobox associated leucine zipper TPR_MLP1_2 PF07926.7 EIE92330.1 - 0.00073 19.2 0.7 0.0011 18.7 0.5 1.2 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.7 EIE92330.1 - 0.0026 16.9 4.4 0.0037 16.4 3.0 1.2 1 0 0 1 1 1 1 Reovirus sigma C capsid protein CCDC155 PF14662.1 EIE92330.1 - 0.0068 16.0 1.2 0.01 15.4 0.8 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 ADIP PF11559.3 EIE92330.1 - 0.0076 16.1 2.1 0.015 15.2 1.4 1.5 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding DUF904 PF06005.7 EIE92330.1 - 0.0093 16.2 2.3 0.019 15.2 1.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF904) DUF972 PF06156.8 EIE92330.1 - 0.022 15.0 0.4 0.041 14.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Phage_GP20 PF06810.6 EIE92330.1 - 0.039 13.4 0.7 0.063 12.7 0.5 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 GAS PF13851.1 EIE92330.1 - 0.048 12.8 1.3 0.073 12.2 0.9 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DivIC PF04977.10 EIE92330.1 - 0.052 13.0 1.3 0.1 12.0 0.5 1.7 1 1 0 1 1 1 0 Septum formation initiator Baculo_PEP_C PF04513.7 EIE92330.1 - 0.072 12.9 7.5 0.12 12.1 5.2 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF869 PF05911.6 EIE92330.1 - 0.093 10.9 2.7 0.14 10.3 1.9 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) DUF2205 PF10224.4 EIE92330.1 - 0.21 11.2 1.7 0.36 10.4 1.2 1.3 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) bZIP_2 PF07716.10 EIE92330.1 - 0.22 11.3 3.3 3.7 7.4 0.1 2.5 1 1 1 2 2 2 0 Basic region leucine zipper DivIVA PF05103.8 EIE92330.1 - 0.22 11.5 2.0 0.31 11.0 0.1 2.0 1 1 1 2 2 2 0 DivIVA protein DUF342 PF03961.8 EIE92330.1 - 0.23 9.8 0.3 0.32 9.3 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DDE_3 PF13358.1 EIE92331.1 - 2.4e-21 76.0 0.0 4e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE92331.1 - 2.6e-11 43.4 0.3 1.3e-10 41.2 0.0 2.2 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.1 EIE92331.1 - 4.2e-06 26.2 0.0 0.00017 21.1 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.1 EIE92331.1 - 6.3e-05 22.8 0.1 0.0011 18.9 0.0 2.7 3 0 0 3 3 3 1 Helix-turn-helix domain PAX PF00292.13 EIE92331.1 - 0.0002 21.0 0.0 0.00038 20.1 0.0 1.4 1 0 0 1 1 1 1 'Paired box' domain HTH_29 PF13551.1 EIE92331.1 - 0.00023 21.2 0.0 0.00086 19.4 0.0 2.0 1 1 0 1 1 1 1 Winged helix-turn helix HTH_11 PF08279.7 EIE92331.1 - 0.00024 20.6 0.3 0.0043 16.6 0.1 2.3 2 0 0 2 2 2 1 HTH domain DDE_Tnp_ISAZ013 PF07592.6 EIE92331.1 - 0.00037 19.3 0.2 0.0038 16.0 0.1 2.0 1 1 0 1 1 1 1 Rhodopirellula transposase DDE domain rve PF00665.21 EIE92331.1 - 0.00051 20.1 0.0 0.0011 19.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain HTH_7 PF02796.10 EIE92331.1 - 0.00066 19.4 1.0 0.035 13.9 0.1 3.0 2 1 0 2 2 2 1 Helix-turn-helix domain of resolvase Trp_repressor PF01371.14 EIE92331.1 - 0.0013 18.5 0.1 0.0034 17.2 0.0 1.7 1 0 0 1 1 1 1 Trp repressor protein HTH_Tnp_ISL3 PF13542.1 EIE92331.1 - 0.0023 17.0 0.0 0.019 14.1 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_26 PF13443.1 EIE92331.1 - 0.014 15.5 0.2 0.22 11.7 0.0 2.7 3 0 0 3 3 3 0 Cro/C1-type HTH DNA-binding domain CENP-B_N PF04218.8 EIE92331.1 - 0.02 14.2 0.1 0.18 11.2 0.1 2.3 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain HTH_38 PF13936.1 EIE92331.1 - 0.059 12.9 0.1 0.23 11.0 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain LacI PF00356.16 EIE92331.1 - 0.1 12.2 0.0 6.2 6.5 0.0 2.6 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family DDE_3 PF13358.1 EIE92333.1 - 1.4e-11 44.3 0.0 2e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE92333.1 - 0.00083 19.3 1.2 0.0049 16.8 0.5 2.4 2 1 1 3 3 3 1 Transposase DUF2567 PF10821.3 EIE92333.1 - 0.12 11.8 0.0 0.18 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2567) DDE_3 PF13358.1 EIE92336.1 - 3.5e-13 49.5 0.2 4.9e-13 49.0 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE92336.1 - 0.016 15.2 0.0 0.025 14.6 0.0 1.3 1 0 0 1 1 1 0 Integrase core domain RRF_GI PF12614.3 EIE92338.1 - 0.1 12.4 0.1 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 Ribosome recycling factor Cornifin PF02389.10 EIE92339.1 - 0.095 12.4 7.8 0.12 12.1 5.4 1.1 1 0 0 1 1 1 0 Cornifin (SPRR) family DDE_3 PF13358.1 EIE92340.1 - 2.7e-17 62.8 0.1 7e-17 61.5 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE92340.1 - 4.9e-10 39.3 0.4 1e-09 38.3 0.3 1.6 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.1 EIE92340.1 - 0.047 14.4 0.1 2 9.2 0.0 2.8 3 0 0 3 3 3 0 Homeodomain-like domain Transposase_21 PF02992.9 EIE92341.1 - 6.4e-17 61.3 0.0 8.5e-17 60.9 0.0 1.2 1 0 0 1 1 1 1 Transposase family tnp2 DDE_3 PF13358.1 EIE92342.1 - 1e-09 38.2 0.9 1.1e-09 38.2 0.6 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE92343.1 - 0.00039 20.4 1.9 0.0011 18.9 1.3 1.9 1 1 1 2 2 2 1 Transposase DDE_3 PF13358.1 EIE92343.1 - 0.026 14.2 0.2 0.063 13.0 0.0 1.7 2 1 0 2 2 2 0 DDE superfamily endonuclease HTH_Tnp_4 PF13613.1 EIE92343.1 - 0.097 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_38 PF13936.1 EIE92344.1 - 3.3e-05 23.3 0.0 6.2e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain UPF0122 PF04297.9 EIE92344.1 - 0.00063 19.7 0.1 0.0013 18.6 0.0 1.4 1 0 0 1 1 1 1 Putative helix-turn-helix protein, YlxM / p13 like HTH_28 PF13518.1 EIE92344.1 - 0.00096 19.1 0.0 0.0014 18.6 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_7 PF02796.10 EIE92344.1 - 0.001 18.8 0.1 0.23 11.3 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_23 PF13384.1 EIE92344.1 - 0.0021 17.6 0.1 0.0052 16.3 0.0 1.7 2 0 0 2 2 2 1 Homeodomain-like domain Sigma70_r4_2 PF08281.7 EIE92344.1 - 0.0039 16.6 0.0 0.0085 15.5 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_32 PF13565.1 EIE92344.1 - 0.0088 16.8 0.3 5.8 7.7 0.0 2.1 2 0 0 2 2 2 2 Homeodomain-like domain Sigma70_r4 PF04545.11 EIE92344.1 - 0.014 14.7 0.0 0.095 12.0 0.0 2.0 2 0 0 2 2 2 0 Sigma-70, region 4 DUF2857 PF11198.3 EIE92344.1 - 0.017 14.6 0.0 0.02 14.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2857) HTH_Tnp_4 PF13613.1 EIE92344.1 - 0.023 14.2 0.1 0.039 13.4 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_29 PF13551.1 EIE92344.1 - 0.029 14.5 0.1 0.041 14.0 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix Trp_repressor PF01371.14 EIE92344.1 - 0.13 12.1 0.2 1.3 8.9 0.0 2.0 2 0 0 2 2 2 0 Trp repressor protein HTH_Tnp_Tc3_2 PF01498.13 EIE92345.1 - 1.3e-07 31.5 0.9 5.5e-07 29.5 0.1 2.2 2 0 0 2 2 2 1 Transposase RVT_1 PF00078.22 EIE92346.1 - 1.9e-13 50.2 0.0 2.1e-13 50.1 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EIE92347.1 - 1.2e-05 24.8 0.0 2.4e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase DDE_Tnp_IS1595 PF12762.2 EIE92348.1 - 2e-07 30.9 0.1 4.6e-07 29.8 0.1 1.6 1 0 0 1 1 1 1 ISXO2-like transposase domain TPR_MLP1_2 PF07926.7 EIE92349.1 - 1.1e-05 25.1 0.8 1.6e-05 24.6 0.6 1.2 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.7 EIE92349.1 - 0.0037 16.4 2.4 0.0054 15.9 1.7 1.2 1 0 0 1 1 1 1 Reovirus sigma C capsid protein DUF972 PF06156.8 EIE92349.1 - 0.0051 17.1 0.3 0.0084 16.4 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF972) DivIVA PF05103.8 EIE92349.1 - 0.019 15.0 0.0 0.036 14.1 0.0 1.5 1 0 0 1 1 1 0 DivIVA protein RasGAP_C PF03836.10 EIE92349.1 - 0.036 13.7 1.3 0.06 13.0 0.9 1.2 1 0 0 1 1 1 0 RasGAP C-terminus PAS_7 PF12860.2 EIE92349.1 - 0.039 13.9 0.2 0.071 13.1 0.1 1.3 1 0 0 1 1 1 0 PAS fold Phage_GP20 PF06810.6 EIE92349.1 - 0.061 12.7 0.1 0.094 12.1 0.1 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 DUF2365 PF10157.4 EIE92349.1 - 0.064 13.1 1.0 4.9 7.0 0.1 2.5 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2365) DivIC PF04977.10 EIE92349.1 - 0.13 11.7 0.9 0.24 10.8 0.6 1.5 1 1 0 1 1 1 0 Septum formation initiator SecIII_SopE_N PF05364.9 EIE92349.1 - 0.18 11.6 0.8 0.31 10.8 0.6 1.3 1 0 0 1 1 1 0 Salmonella type III secretion SopE effector N-terminus DUF3446 PF11928.3 EIE92349.1 - 0.4 10.9 9.1 1.8 8.7 5.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) Adeno_PIX PF03955.9 EIE92349.1 - 2.1 8.9 6.2 0.35 11.4 0.7 2.1 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) GCR1_C PF12550.3 EIE92350.1 - 5.2e-26 90.3 0.7 5.1e-25 87.1 0.2 2.6 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes HTH_Tnp_Tc3_2 PF01498.13 EIE92351.1 - 1.1e-09 38.2 0.5 2.8e-09 36.8 0.4 1.8 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.1 EIE92351.1 - 3.5e-05 23.9 1.6 5e-05 23.4 1.1 1.2 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EIE92351.1 - 0.00073 19.1 0.6 0.014 15.0 0.0 2.5 3 0 0 3 3 3 1 Homeodomain-like domain HTH_7 PF02796.10 EIE92351.1 - 0.0017 18.1 0.7 0.23 11.3 0.1 2.7 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HIGH_NTase1 PF05636.6 EIE92351.1 - 0.074 12.0 0.3 0.094 11.7 0.2 1.2 1 0 0 1 1 1 0 HIGH Nucleotidyl Transferase DDE_3 PF13358.1 EIE92352.1 - 6.5e-18 64.8 0.1 1.1e-17 64.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE92352.1 - 1.1e-08 35.0 0.8 4.4e-08 33.0 0.4 2.0 2 0 0 2 2 2 1 Transposase DASH_Spc34 PF08657.5 EIE92353.1 - 0.058 13.0 2.4 0.49 10.0 0.1 2.1 2 0 0 2 2 2 0 DASH complex subunit Spc34 PI31_Prot_N PF11566.3 EIE92353.1 - 0.11 12.0 1.2 0.33 10.5 0.9 1.8 1 1 0 1 1 1 0 PI31 proteasome regulator N-terminal DUF4168 PF13767.1 EIE92353.1 - 0.25 12.0 1.5 1.3 9.7 1.1 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4168) ATP-synt_10 PF05176.9 EIE92356.1 - 0.09 12.0 0.1 0.099 11.9 0.0 1.1 1 0 0 1 1 1 0 ATP10 protein TMF_TATA_bd PF12325.3 EIE92357.1 - 5.4e-24 84.2 15.0 5.4e-24 84.2 10.4 2.8 1 1 0 2 2 2 1 TATA element modulatory factor 1 TATA binding DUF2205 PF10224.4 EIE92357.1 - 0.0053 16.3 1.6 0.0053 16.3 1.1 4.7 2 1 3 5 5 5 1 Predicted coiled-coil protein (DUF2205) AAA_13 PF13166.1 EIE92357.1 - 0.018 13.5 33.7 0.033 12.6 18.4 2.0 1 1 1 2 2 2 0 AAA domain CCDC-167 PF15188.1 EIE92357.1 - 0.066 13.1 0.6 0.066 13.1 0.4 4.1 2 1 2 4 4 3 0 Coiled-coil domain-containing protein 167 IncA PF04156.9 EIE92357.1 - 0.081 12.5 57.4 0.26 10.8 16.4 2.6 1 1 1 2 2 2 0 IncA protein ADIP PF11559.3 EIE92357.1 - 0.11 12.4 47.8 0.055 13.3 6.0 3.9 1 1 3 4 4 3 0 Afadin- and alpha -actinin-Binding Reo_sigmaC PF04582.7 EIE92357.1 - 0.13 11.4 10.8 0.72 8.9 0.4 2.8 2 1 1 3 3 3 0 Reovirus sigma C capsid protein ERM PF00769.14 EIE92357.1 - 0.3 10.6 48.7 0.42 10.1 7.3 3.0 1 1 2 3 3 3 0 Ezrin/radixin/moesin family DivIVA PF05103.8 EIE92357.1 - 0.6 10.1 33.2 1.1 9.2 9.8 3.0 1 1 2 3 3 3 0 DivIVA protein NPV_P10 PF05531.7 EIE92357.1 - 0.78 10.0 20.2 1.1 9.5 1.7 4.1 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein KIP1 PF07765.7 EIE92357.1 - 1.5 8.6 8.1 1.6 8.5 0.1 3.2 2 2 2 4 4 4 0 KIP1-like protein DUF972 PF06156.8 EIE92357.1 - 3.1 8.1 37.3 4.6 7.6 8.3 4.0 1 1 2 3 3 3 0 Protein of unknown function (DUF972) DUF2852 PF11014.3 EIE92357.1 - 3.3 7.6 10.5 0.12 12.3 2.4 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2852) Prominin PF05478.6 EIE92357.1 - 3.8 4.9 18.3 1.2 6.5 10.6 1.7 1 1 1 2 2 2 0 Prominin CCDC155 PF14662.1 EIE92357.1 - 3.8 7.0 52.1 0.28 10.7 14.0 2.1 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 GAS PF13851.1 EIE92357.1 - 7.2 5.7 48.5 8.4 5.5 13.1 2.7 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF3584 PF12128.3 EIE92357.1 - 9.4 3.4 42.1 13 2.9 28.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) DDE_3 PF13358.1 EIE92359.1 - 7.5e-21 74.4 0.1 7.8e-20 71.1 0.1 2.3 1 1 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.14 EIE92359.1 - 0.0021 17.2 0.1 0.0046 16.1 0.1 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease Serglycin PF04360.7 EIE92359.1 - 0.033 13.9 0.0 1.4 8.6 0.0 2.3 2 0 0 2 2 2 0 Serglycin Transposase_31 PF04754.7 EIE92360.1 - 0.054 12.8 0.0 0.092 12.0 0.0 1.4 1 0 0 1 1 1 0 Putative transposase, YhgA-like HTH_Tnp_Tc3_2 PF01498.13 EIE92362.1 - 7.9e-08 32.2 0.9 2.1e-07 30.8 0.4 1.9 1 1 1 2 2 2 1 Transposase DDE_3 PF13358.1 EIE92362.1 - 0.002 17.8 0.0 0.0046 16.7 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease RVT_1 PF00078.22 EIE92363.1 - 0.005 16.2 0.0 0.0092 15.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GNAT_acetyltran PF12746.2 EIE92363.1 - 0.094 11.5 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase Exo_endo_phos_2 PF14529.1 EIE92364.1 - 1.5e-10 40.7 0.0 2.8e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EIE92364.1 - 5.7e-06 26.4 0.4 7.4e-06 26.0 0.3 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-CCHC_6 PF15288.1 EIE92365.1 - 6.1e-05 22.6 4.1 0.091 12.4 1.0 2.7 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC PF00098.18 EIE92365.1 - 0.00019 21.2 15.4 0.0003 20.5 1.9 3.4 3 0 0 3 3 3 2 Zinc knuckle NMD3 PF04981.8 EIE92365.1 - 0.12 11.4 3.2 0.12 11.5 0.7 1.8 2 0 0 2 2 2 0 NMD3 family zf-CCHC_4 PF14392.1 EIE92365.1 - 1.8 8.2 15.2 3.4 7.4 0.8 3.3 3 0 0 3 3 3 0 Zinc knuckle zf-CCHC_2 PF13696.1 EIE92365.1 - 8.3 6.0 9.2 15 5.1 1.1 2.8 1 1 1 2 2 2 0 Zinc knuckle DDE_3 PF13358.1 EIE92368.1 - 7.7e-20 71.1 0.0 1.8e-19 69.9 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE92368.1 - 1.2e-07 31.6 2.8 3.1e-06 27.1 1.1 2.8 3 0 0 3 3 3 1 Transposase HTH_23 PF13384.1 EIE92368.1 - 6.2e-06 25.7 0.1 0.00048 19.6 0.0 2.9 3 0 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.1 EIE92368.1 - 0.0023 17.8 0.5 0.29 11.2 0.0 2.7 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_17 PF12728.2 EIE92368.1 - 0.0079 16.4 0.1 0.096 12.9 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_29 PF13551.1 EIE92368.1 - 0.018 15.1 0.5 0.24 11.5 0.0 2.8 2 1 1 3 3 3 0 Winged helix-turn helix Sigma70_r4_2 PF08281.7 EIE92368.1 - 0.024 14.1 0.0 0.061 12.7 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_Tnp_ISL3 PF13542.1 EIE92368.1 - 0.055 12.6 0.0 0.5 9.5 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 GerE PF00196.14 EIE92368.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family Transposase_21 PF02992.9 EIE92369.1 - 9.6e-22 77.1 0.0 1.6e-21 76.4 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DUF1258 PF06869.7 EIE92369.1 - 0.0026 16.9 0.0 0.0041 16.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) LysR_substrate PF03466.15 EIE92369.1 - 0.16 11.0 0.0 0.29 10.1 0.0 1.3 1 0 0 1 1 1 0 LysR substrate binding domain DUF1203 PF06718.6 EIE92370.1 - 0.022 14.5 0.0 0.029 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1203) DUF3983 PF13137.1 EIE92370.1 - 0.11 12.1 0.9 2.7 7.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3983) VIT1 PF01988.14 EIE92371.1 - 0.34 10.3 1.3 0.47 9.9 0.9 1.2 1 0 0 1 1 1 0 VIT family Gastrin PF00918.12 EIE92371.1 - 1.6 9.5 8.2 2.4 9.0 5.7 1.3 1 0 0 1 1 1 0 Gastrin/cholecystokinin family Cornifin PF02389.10 EIE92373.1 - 0.0021 17.8 5.1 0.0035 17.1 3.5 1.3 1 0 0 1 1 1 1 Cornifin (SPRR) family Cse1 PF08506.5 EIE92373.1 - 0.0083 14.7 0.8 0.011 14.3 0.5 1.0 1 0 0 1 1 1 1 Cse1 PE_PPE_C PF12484.3 EIE92373.1 - 0.04 14.8 13.9 0.077 13.9 9.7 1.4 1 0 0 1 1 1 0 Polymorphic PE/PPE proteins C terminal DDE_Tnp_IS1595 PF12762.2 EIE92374.1 - 4.5e-07 29.8 0.1 1.1e-06 28.5 0.1 1.6 1 0 0 1 1 1 1 ISXO2-like transposase domain RVT_1 PF00078.22 EIE92375.1 - 3.6e-21 75.5 0.0 4.2e-21 75.2 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_Tnp_IS1595 PF12762.2 EIE92376.1 - 2.2e-13 50.3 0.0 1.8e-07 31.1 0.0 2.7 1 1 1 2 2 2 2 ISXO2-like transposase domain FlgM PF04316.8 EIE92377.1 - 0.55 10.2 4.1 4.3 7.3 2.8 2.2 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM DDE_3 PF13358.1 EIE92378.1 - 2e-16 60.0 0.7 7.6e-14 51.6 0.1 2.4 1 1 1 2 2 2 2 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE92378.1 - 2.8e-06 27.2 0.3 6e-06 26.2 0.2 1.6 1 0 0 1 1 1 1 Transposase TPR_MLP1_2 PF07926.7 EIE92379.1 - 9.9e-05 22.0 0.3 0.00014 21.6 0.2 1.2 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein HALZ PF02183.13 EIE92379.1 - 0.00065 19.3 1.0 0.0015 18.1 0.4 1.9 1 1 0 1 1 1 1 Homeobox associated leucine zipper DUF904 PF06005.7 EIE92379.1 - 0.0073 16.5 2.4 0.015 15.5 1.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF904) Reo_sigmaC PF04582.7 EIE92379.1 - 0.016 14.4 4.0 0.023 13.9 2.8 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein ADIP PF11559.3 EIE92379.1 - 0.017 15.0 1.8 0.036 13.9 1.3 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF972 PF06156.8 EIE92379.1 - 0.022 15.1 0.4 0.041 14.2 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Mod_r PF07200.8 EIE92379.1 - 0.033 14.0 0.7 0.067 13.1 0.5 1.5 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Cluap1 PF10234.4 EIE92379.1 - 0.038 13.2 0.6 0.055 12.6 0.4 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 MAD PF05557.8 EIE92379.1 - 0.038 12.0 1.2 0.051 11.6 0.8 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein DivIC PF04977.10 EIE92379.1 - 0.048 13.1 1.3 0.093 12.2 0.5 1.7 1 1 1 2 2 2 0 Septum formation initiator Baculo_PEP_C PF04513.7 EIE92379.1 - 0.06 13.1 6.9 0.1 12.4 4.8 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus GAS PF13851.1 EIE92379.1 - 0.069 12.3 1.9 0.1 11.7 1.3 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Phage_GP20 PF06810.6 EIE92379.1 - 0.071 12.5 0.9 0.12 11.7 0.6 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 DUF342 PF03961.8 EIE92379.1 - 0.13 10.6 0.3 0.18 10.1 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF2205 PF10224.4 EIE92379.1 - 0.14 11.7 2.4 0.26 10.9 1.6 1.4 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) bZIP_2 PF07716.10 EIE92379.1 - 0.22 11.3 3.3 3.7 7.4 0.1 2.5 1 1 1 2 2 2 0 Basic region leucine zipper DivIVA PF05103.8 EIE92379.1 - 0.26 11.3 1.8 0.42 10.6 0.1 2.0 1 1 1 2 2 2 0 DivIVA protein Rootletin PF15035.1 EIE92379.1 - 0.69 9.8 4.5 1.2 9.0 3.1 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion RVT_1 PF00078.22 EIE92382.1 - 2.8e-16 59.5 0.0 5.1e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EIE92382.1 - 1.4e-05 24.6 0.0 3.5e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase TPR_MLP1_2 PF07926.7 EIE92383.1 - 0.00013 21.7 0.4 0.00021 21.0 0.3 1.2 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein Phage_GP20 PF06810.6 EIE92383.1 - 0.00032 20.1 0.4 0.00048 19.6 0.3 1.2 1 0 0 1 1 1 1 Phage minor structural protein GP20 Med4 PF10018.4 EIE92383.1 - 0.0043 16.4 0.1 0.0061 15.9 0.1 1.2 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 SlyX PF04102.7 EIE92383.1 - 0.0052 17.1 0.3 0.015 15.6 0.2 1.8 1 0 0 1 1 1 1 SlyX DUF972 PF06156.8 EIE92383.1 - 0.0075 16.5 0.3 0.013 15.8 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF972) DivIVA PF05103.8 EIE92383.1 - 0.017 15.1 0.1 0.028 14.4 0.1 1.4 1 0 0 1 1 1 0 DivIVA protein Cluap1 PF10234.4 EIE92383.1 - 0.019 14.1 0.2 0.027 13.6 0.2 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 Rogdi_lz PF10259.4 EIE92383.1 - 0.032 13.3 1.4 0.048 12.7 0.9 1.2 1 0 0 1 1 1 0 Rogdi leucine zipper containing protein DivIC PF04977.10 EIE92383.1 - 0.032 13.6 0.2 0.064 12.7 0.1 1.5 1 0 0 1 1 1 0 Septum formation initiator HALZ PF02183.13 EIE92383.1 - 0.04 13.6 1.5 0.1 12.3 1.1 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper Baculo_PEP_C PF04513.7 EIE92383.1 - 0.062 13.1 8.2 0.11 12.3 5.7 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus MAD PF05557.8 EIE92383.1 - 0.066 11.3 0.8 0.098 10.7 0.6 1.2 1 0 0 1 1 1 0 Mitotic checkpoint protein Reo_sigmaC PF04582.7 EIE92383.1 - 0.2 10.8 5.0 0.28 10.3 3.5 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein FliD_N PF02465.13 EIE92383.1 - 0.42 11.0 4.2 0.35 11.2 1.6 1.8 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus RVT_1 PF00078.22 EIE92384.1 - 2e-22 79.6 0.0 3.1e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EIE92384.1 - 2.7e-05 23.7 0.0 7.1e-05 22.4 0.0 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase PARP_regulatory PF01358.13 EIE92385.1 - 0.018 13.7 0.6 0.024 13.2 0.4 1.1 1 0 0 1 1 1 0 Poly A polymerase regulatory subunit FlgM PF04316.8 EIE92385.1 - 2 8.4 4.8 4.9 7.1 3.3 1.6 1 0 0 1 1 1 0 Anti-sigma-28 factor, FlgM Transposase_21 PF02992.9 EIE92386.1 - 3.7e-22 78.5 0.1 8e-22 77.4 0.1 1.5 1 0 0 1 1 1 1 Transposase family tnp2 SHR3_chaperone PF08229.6 EIE92386.1 - 0.04 12.8 0.1 0.1 11.5 0.1 1.6 1 0 0 1 1 1 0 ER membrane protein SH3 3HCDH_N PF02737.13 EIE92386.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF3741 PF12552.3 EIE92387.1 - 0.12 12.0 0.4 6.7 6.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3741) Sialidase PF02973.11 EIE92387.1 - 0.13 11.2 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 Sialidase, N-terminal domain DDE_3 PF13358.1 EIE92388.1 - 5.6e-12 45.6 0.0 6.1e-12 45.5 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease Transposase_21 PF02992.9 EIE92392.1 - 5e-09 35.5 0.0 1.9e-07 30.4 0.0 2.2 1 1 1 2 2 2 2 Transposase family tnp2 FKBP_N PF01346.13 EIE92394.1 - 0.0027 17.7 1.7 0.0027 17.7 1.2 1.6 2 0 0 2 2 2 1 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase DUF3708 PF12501.3 EIE92394.1 - 0.035 13.9 0.2 0.055 13.2 0.1 1.3 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter HTH_37 PF13744.1 EIE92394.1 - 0.098 12.4 5.4 5.9 6.7 3.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain AHSP PF09236.5 EIE92394.1 - 0.1 12.8 0.3 0.15 12.3 0.2 1.2 1 0 0 1 1 1 0 Alpha-haemoglobin stabilising protein DivIC PF04977.10 EIE92394.1 - 3.6 7.1 6.9 3.1 7.3 3.3 1.8 2 0 0 2 2 2 0 Septum formation initiator Retrotrans_gag PF03732.12 EIE92398.1 - 4.6e-09 36.2 2.5 1.1e-08 34.9 0.4 2.0 2 0 0 2 2 2 1 Retrotransposon gag protein DUF3573 PF12097.3 EIE92398.1 - 0.0052 15.4 0.2 0.0098 14.5 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3573) zf-CCHC PF00098.18 EIE92398.1 - 0.029 14.2 0.6 0.044 13.7 0.4 1.3 1 0 0 1 1 1 0 Zinc knuckle Phage_integrase PF00589.17 EIE92400.1 - 0.00017 21.3 0.1 0.00026 20.7 0.1 1.3 1 0 0 1 1 1 1 Phage integrase family BUD22 PF09073.5 EIE92400.1 - 0.035 13.1 1.3 0.041 12.9 0.9 1.0 1 0 0 1 1 1 0 BUD22 DUF1125 PF06563.6 EIE92402.1 - 0.14 11.8 0.3 2 8.1 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1125) PrmA PF06325.8 EIE92404.1 - 0.036 13.1 1.9 0.33 10.0 0.0 2.0 1 1 1 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Borrelia_orfD PF02999.9 EIE92404.1 - 0.087 12.9 0.3 0.62 10.2 0.1 2.2 2 0 0 2 2 2 0 Borrelia orf-D family PH PF00169.24 EIE92405.1 - 3.9e-14 52.7 0.2 3.9e-14 52.7 0.2 3.4 2 2 1 3 3 3 1 PH domain GRAM PF02893.15 EIE92405.1 - 4.2e-05 22.9 0.0 8.7e-05 21.9 0.0 1.6 1 0 0 1 1 1 1 GRAM domain PH_11 PF15413.1 EIE92405.1 - 0.018 15.3 1.2 0.018 15.3 0.9 4.0 3 1 0 3 3 3 0 Pleckstrin homology domain bPH_3 PF14470.1 EIE92405.1 - 0.05 13.8 0.0 0.17 12.1 0.0 2.0 1 0 0 1 1 1 0 Bacterial PH domain Dynamin_N PF00350.18 EIE92407.1 - 1.6e-16 60.5 4.2 1.9e-16 60.3 0.0 3.1 3 2 1 4 4 4 1 Dynamin family MMR_HSR1 PF01926.18 EIE92407.1 - 1.4e-09 37.8 0.4 1.3e-08 34.8 0.1 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EIE92407.1 - 2.2e-07 30.4 1.0 6.4e-06 25.7 0.7 2.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Miro PF08477.8 EIE92407.1 - 0.0019 18.6 0.1 0.13 12.7 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein AAA_29 PF13555.1 EIE92407.1 - 0.003 17.0 0.1 0.0071 15.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain cobW PF02492.14 EIE92407.1 - 0.0076 15.7 0.4 1.3 8.4 0.0 2.8 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.13 EIE92407.1 - 0.024 13.6 0.6 0.16 10.9 0.0 2.4 2 1 1 3 3 3 0 Septin PglZ PF08665.7 EIE92407.1 - 0.038 13.6 0.5 0.41 10.3 0.1 2.5 2 0 0 2 2 2 0 PglZ domain FtsK_SpoIIIE PF01580.13 EIE92407.1 - 0.045 13.2 0.0 0.12 11.7 0.0 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_18 PF13238.1 EIE92407.1 - 0.084 13.1 0.7 0.69 10.2 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.1 EIE92407.1 - 0.091 12.1 0.1 0.69 9.2 0.0 2.6 3 0 0 3 3 3 0 AAA domain PIG-U PF06728.8 EIE92408.1 - 1.4e-27 96.5 13.9 1.7e-27 96.3 9.7 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Ribosomal_S27e PF01667.12 EIE92409.1 - 1.4e-29 101.3 4.0 1.7e-29 101.1 2.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 EIE92409.1 - 0.00029 20.6 1.2 0.00035 20.3 0.8 1.2 1 0 0 1 1 1 1 IBR domain TF_Zn_Ribbon PF08271.7 EIE92409.1 - 0.00084 18.6 2.5 0.0012 18.0 1.7 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding Prok-RING_1 PF14446.1 EIE92409.1 - 0.093 12.4 1.1 0.15 11.8 0.7 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 OrfB_Zn_ribbon PF07282.6 EIE92409.1 - 0.14 11.8 1.1 0.18 11.4 0.8 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-ribbon_3 PF13248.1 EIE92409.1 - 0.2 10.9 3.0 4.2 6.7 0.4 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EIE92409.1 - 0.24 11.1 2.6 9.3 6.0 1.8 2.3 1 1 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EIE92409.1 - 0.34 10.5 2.7 13 5.4 1.9 2.3 1 1 0 1 1 1 0 zinc-ribbon domain Tnp_zf-ribbon_2 PF13842.1 EIE92409.1 - 0.42 11.0 2.5 0.93 9.9 1.7 1.7 1 1 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon zf-C2HC5 PF06221.8 EIE92409.1 - 0.43 10.3 4.6 0.11 12.3 0.8 1.8 1 1 0 1 1 1 0 Putative zinc finger motif, C2HC5-type RecR PF02132.10 EIE92409.1 - 1 8.8 3.8 2.6 7.5 0.6 2.2 2 0 0 2 2 2 0 RecR protein Acyltransferase PF01553.16 EIE92410.1 - 1.4e-15 56.8 0.0 2.7e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase RPE65 PF03055.10 EIE92411.1 - 3.9e-56 190.5 0.2 2e-53 181.6 0.1 2.2 1 1 0 1 1 1 1 Retinal pigment epithelial membrane protein Peptidase_M17 PF00883.16 EIE92412.1 - 5.9e-39 133.7 0.0 2e-38 132.0 0.0 1.8 1 1 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Pmp3 PF01679.12 EIE92412.1 - 3.1e-17 61.9 3.0 5.5e-17 61.2 2.1 1.3 1 0 0 1 1 1 1 Proteolipid membrane potential modulator 2-Hacid_dh_C PF02826.14 EIE92413.1 - 1.4e-55 187.1 0.0 1.8e-55 186.8 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EIE92413.1 - 0.0016 18.5 0.0 0.0028 17.7 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.10 EIE92413.1 - 0.012 15.4 0.0 0.019 14.8 0.0 1.2 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 EIE92413.1 - 0.013 14.8 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 EIE92413.1 - 0.028 14.8 0.0 0.056 13.8 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.17 EIE92413.1 - 0.067 13.7 0.0 0.13 12.8 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold 2-Hacid_dh PF00389.25 EIE92413.1 - 0.12 11.8 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain IDO PF01231.13 EIE92414.1 - 4.7e-130 433.8 0.0 8.5e-130 432.9 0.0 1.4 1 1 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF1864 PF08933.6 EIE92414.1 - 0.13 10.7 0.0 0.27 9.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1864) GPI-anchored PF10342.4 EIE92416.1 - 8.6e-06 26.1 0.7 1.8e-05 25.1 0.5 1.5 1 1 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF3304 PF11745.3 EIE92416.1 - 0.068 13.3 0.1 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3304) DUF4448 PF14610.1 EIE92416.1 - 0.069 12.6 0.1 0.073 12.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) FCH PF00611.18 EIE92417.1 - 5.7e-10 39.2 5.1 1.6e-09 37.8 0.2 3.5 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain RhoGAP PF00620.22 EIE92417.1 - 7.1e-09 35.4 1.6 1.8e-08 34.1 0.4 2.3 2 0 0 2 2 2 1 RhoGAP domain DEP PF00610.16 EIE92417.1 - 6.8e-08 32.1 0.1 1.5e-07 31.0 0.1 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) BMFP PF04380.8 EIE92417.1 - 0.061 13.4 0.4 0.26 11.4 0.3 2.1 1 1 0 1 1 1 0 Membrane fusogenic activity Acetyltransf_11 PF13720.1 EIE92417.1 - 2.3 8.4 5.1 0.87 9.8 0.1 2.9 4 0 0 4 4 4 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Meth_synt_2 PF01717.13 EIE92418.1 - 4.9e-153 508.8 0.0 4.5e-139 462.9 0.0 3.0 3 0 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EIE92418.1 - 1.8e-120 401.8 0.0 4.6e-107 357.8 0.2 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain p450 PF00067.17 EIE92419.1 - 2.5e-54 184.5 0.0 3e-54 184.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2076 PF09849.4 EIE92420.1 - 4e-08 33.6 13.4 4.6e-08 33.4 9.3 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 EIE92420.1 - 2.6e-06 27.1 6.1 4.9e-06 26.3 4.3 1.5 1 0 0 1 1 1 1 CHCH domain DUF1903 PF08991.5 EIE92420.1 - 0.0023 18.0 3.1 0.0049 16.9 2.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) RAB3GAP2_N PF14655.1 EIE92420.1 - 0.044 12.7 2.4 0.061 12.3 1.6 1.4 1 1 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Neur_chan_memb PF02932.11 EIE92420.1 - 0.94 9.3 6.2 1.1 9.0 4.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF3451 PF11933.3 EIE92420.1 - 1.5 8.5 10.3 0.17 11.6 1.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3451) GET2 PF08690.5 EIE92420.1 - 2 7.5 4.9 2.8 7.1 3.4 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 DUF605 PF04652.11 EIE92420.1 - 2.2 7.5 17.8 2.8 7.2 12.3 1.2 1 0 0 1 1 1 0 Vta1 like V-ATPase_C PF03223.10 EIE92422.1 - 1.6e-116 389.3 10.8 1.7e-116 389.1 7.5 1.0 1 0 0 1 1 1 1 V-ATPase subunit C Synaptobrevin PF00957.16 EIE92422.1 - 0.099 12.2 1.2 0.28 10.7 0.5 2.1 2 0 0 2 2 2 0 Synaptobrevin HrpB2 PF09487.5 EIE92422.1 - 0.19 11.8 2.4 0.35 11.0 1.7 1.5 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB2) DUF3936 PF13072.1 EIE92422.1 - 0.47 9.9 1.7 15 5.1 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3936) Pkinase PF00069.20 EIE92423.1 - 1.5e-61 207.8 0.1 2.1e-61 207.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE92423.1 - 9.8e-47 159.1 0.0 1.4e-46 158.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE92423.1 - 2.9e-05 23.1 0.0 9.6e-05 21.4 0.0 1.8 1 1 0 2 2 2 1 Kinase-like RIO1 PF01163.17 EIE92423.1 - 0.008 15.5 0.1 0.019 14.2 0.0 1.7 2 1 0 2 2 2 1 RIO1 family Seadorna_VP7 PF07387.6 EIE92423.1 - 0.021 13.6 0.0 0.036 12.9 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 PIP49_C PF12260.3 EIE92423.1 - 0.066 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Kdo PF06293.9 EIE92423.1 - 0.11 11.6 0.0 0.18 10.8 0.0 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pap_E4 PF02711.9 EIE92423.1 - 0.12 13.1 1.7 0.25 12.1 1.2 1.4 1 0 0 1 1 1 0 E4 protein YL1 PF05764.8 EIE92424.1 - 0.041 13.5 18.0 0.19 11.3 12.5 2.1 1 0 0 1 1 1 0 YL1 nuclear protein zf-C3HC PF07967.8 EIE92425.1 - 4.3e-19 68.6 1.6 6.7e-19 67.9 0.2 1.9 2 0 0 2 2 2 1 C3HC zinc finger-like Ndc1_Nup PF09531.5 EIE92425.1 - 0.59 8.4 3.9 0.73 8.1 2.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RICTOR_N PF14664.1 EIE92426.1 - 1.3e-82 277.3 2.3 1.3e-80 270.7 0.9 2.8 2 1 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.1 EIE92426.1 - 7e-82 273.8 1.9 3.7e-79 264.8 0.1 3.7 3 1 1 4 4 4 2 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.1 EIE92426.1 - 6.8e-40 135.5 0.1 8.1e-37 125.6 0.0 2.8 2 0 0 2 2 2 2 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 EIE92426.1 - 1.6e-30 104.8 5.6 8.2e-29 99.3 0.1 4.7 6 0 0 6 6 6 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.11 EIE92426.1 - 9.7e-07 28.4 4.5 3.5e-06 26.6 3.1 2.0 1 0 0 1 1 1 1 Hr1 repeat HEAT_2 PF13646.1 EIE92426.1 - 1.3e-06 28.5 1.1 0.27 11.5 0.1 5.0 4 0 0 4 4 4 2 HEAT repeats Arm PF00514.18 EIE92426.1 - 0.83 9.5 8.5 55 3.7 0.0 5.5 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat Vps52 PF04129.7 EIE92427.1 - 1.2e-20 73.5 0.7 1.2e-20 73.5 0.5 1.5 2 0 0 2 2 2 1 Vps52 / Sac2 family zf-RING_2 PF13639.1 EIE92427.1 - 1.1e-08 34.7 1.4 1.7e-08 34.1 0.2 1.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 EIE92427.1 - 1.3e-06 27.9 0.4 3e-06 26.8 0.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIE92427.1 - 2e-06 27.6 0.4 5.2e-06 26.3 0.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EIE92427.1 - 2.1e-05 24.5 1.5 2.9e-05 24.1 0.2 1.9 2 0 0 2 2 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EIE92427.1 - 2.7e-05 23.7 0.1 7e-05 22.4 0.1 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EIE92427.1 - 3.3e-05 23.4 0.3 6.1e-05 22.6 0.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EIE92427.1 - 4.8e-05 23.1 0.5 0.00014 21.6 0.4 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 EIE92427.1 - 0.00048 19.9 0.3 0.00093 18.9 0.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EIE92427.1 - 0.0011 18.6 0.3 0.0011 18.6 0.2 2.7 2 1 1 3 3 2 1 RING-type zinc-finger zf-Nse PF11789.3 EIE92427.1 - 0.027 13.9 0.1 0.079 12.4 0.1 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DegS PF05384.6 EIE92427.1 - 0.028 13.6 6.1 0.054 12.7 4.2 1.5 1 0 0 1 1 1 0 Sensor protein DegS nsp7 PF08716.5 EIE92427.1 - 0.05 13.9 0.4 0.29 11.5 0.0 2.4 2 0 0 2 2 2 0 nsp7 replicase FANCL_C PF11793.3 EIE92427.1 - 0.057 13.3 0.7 0.14 12.1 0.5 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.2 EIE92427.1 - 0.099 12.7 1.2 0.25 11.4 0.8 1.7 1 0 0 1 1 1 0 RING-variant domain GAGA PF09237.6 EIE92427.1 - 0.11 12.1 1.6 0.24 11.0 1.1 1.6 1 0 0 1 1 1 0 GAGA factor COG2 PF06148.6 EIE92427.1 - 0.2 11.5 11.0 0.15 11.9 2.6 2.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Rad50_zn_hook PF04423.9 EIE92427.1 - 0.38 10.2 3.7 5.8 6.4 0.0 3.2 3 0 0 3 3 3 0 Rad50 zinc hook motif DUF3373 PF11853.3 EIE92427.1 - 0.4 9.1 2.1 0.53 8.7 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Rho_Binding PF08912.6 EIE92427.1 - 0.95 9.8 7.9 4.1 7.7 0.1 3.4 3 1 0 3 3 3 0 Rho Binding SlyX PF04102.7 EIE92427.1 - 1.2 9.5 6.1 4 7.8 0.5 2.7 2 0 0 2 2 2 0 SlyX UPF0547 PF10571.4 EIE92427.1 - 1.6 8.4 5.5 1 9.1 0.2 2.7 3 0 0 3 3 2 0 Uncharacterised protein family UPF0547 NPV_P10 PF05531.7 EIE92427.1 - 2.7 8.3 7.5 2.7 8.3 1.3 2.8 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein IncA PF04156.9 EIE92427.1 - 6.5 6.2 16.0 13 5.2 7.0 2.2 1 1 1 2 2 2 0 IncA protein Vps52 PF04129.7 EIE92428.1 - 4e-19 68.5 0.0 4.3e-19 68.4 0.0 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family MIT PF04212.13 EIE92430.1 - 1.6e-08 34.2 1.7 2.8e-08 33.5 0.2 2.3 1 1 1 2 2 2 1 MIT (microtubule interacting and transport) domain KilA-N PF04383.8 EIE92431.1 - 0.00015 21.3 0.0 0.00032 20.3 0.0 1.6 1 1 0 1 1 1 1 KilA-N domain Med25_SD1 PF11235.3 EIE92431.1 - 0.0073 16.6 0.0 0.012 15.9 0.0 1.4 1 0 0 1 1 1 1 Mediator complex subunit 25 synapsin 1 Mur_ligase_M PF08245.7 EIE92432.1 - 4.7e-08 33.3 1.0 1.5e-06 28.4 0.7 3.0 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.16 EIE92432.1 - 0.0034 17.3 0.0 0.0079 16.2 0.0 1.6 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain Mito_carr PF00153.22 EIE92433.1 - 2.9e-37 126.2 8.1 1.2e-16 60.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein tRNA-synt_His PF13393.1 EIE92436.1 - 1.6e-40 139.0 0.1 1.9e-40 138.8 0.0 1.1 1 0 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 EIE92436.1 - 1.4e-20 73.5 0.0 2.9e-20 72.5 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EIE92436.1 - 5.7e-12 45.4 0.6 1.3e-11 44.2 0.2 1.8 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2 PF00152.15 EIE92436.1 - 4.7e-06 25.6 0.0 0.0016 17.2 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 EIE92436.1 - 0.0074 15.5 0.0 0.095 11.8 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) HGTP_anticodon2 PF12745.2 EIE92436.1 - 0.012 14.8 0.2 0.016 14.3 0.2 1.2 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs Herpes_UL87 PF03043.9 EIE92437.1 - 0.23 9.8 8.0 0.27 9.5 5.5 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family DUF2572 PF10833.3 EIE92437.1 - 1.7 7.9 13.4 2.6 7.3 9.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2572) DUF4517 PF15006.1 EIE92437.1 - 3.7 7.3 6.9 0.59 9.9 0.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4517) Acetyltransf_1 PF00583.19 EIE92439.1 - 4.7e-11 42.5 0.0 7.4e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EIE92439.1 - 3e-08 33.7 0.0 5.1e-08 32.9 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EIE92439.1 - 2.1e-06 27.3 0.0 3.2e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EIE92439.1 - 2.8e-05 24.2 0.0 3.5e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EIE92439.1 - 0.00015 21.6 0.2 0.00038 20.2 0.1 1.7 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EIE92439.1 - 0.015 15.2 0.1 0.062 13.1 0.0 1.9 1 1 1 2 2 2 0 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.1 EIE92439.1 - 0.039 13.8 0.0 0.065 13.1 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain PAT1 PF09770.4 EIE92440.1 - 1.4 7.0 16.8 1.5 6.9 11.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Phostensin_N PF13916.1 EIE92440.1 - 2.2 8.3 5.4 1 9.3 2.2 1.6 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal BAF1_ABF1 PF04684.8 EIE92440.1 - 9 5.0 13.1 12 4.5 9.1 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Sugar_tr PF00083.19 EIE92441.1 - 8.8e-39 133.3 23.8 3.5e-37 128.0 16.6 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIE92441.1 - 5.4e-32 110.8 38.9 1.1e-31 109.8 27.1 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily ATG22 PF11700.3 EIE92441.1 - 1.7e-05 23.5 25.5 8e-05 21.2 11.7 2.3 1 1 1 2 2 2 2 Vacuole effluxer Atg22 like MFS_1_like PF12832.2 EIE92441.1 - 0.15 11.8 4.0 0.71 9.7 0.0 2.8 2 0 0 2 2 2 0 MFS_1 like family DNA_pol_A_exo1 PF01612.15 EIE92442.1 - 1.9e-48 164.2 0.7 3.2e-48 163.5 0.5 1.4 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.7 EIE92442.1 - 1.9e-14 53.7 0.5 1.1e-13 51.2 0.0 2.5 3 0 0 3 3 3 1 PMC2NT (NUC016) domain HRDC PF00570.18 EIE92442.1 - 1.3e-12 47.1 0.1 1e-11 44.3 0.0 2.3 2 0 0 2 2 2 1 HRDC domain RIO1 PF01163.17 EIE92443.1 - 7.9e-55 185.1 0.9 7.9e-55 185.1 0.6 3.0 3 1 0 3 3 3 1 RIO1 family Peptidase_M24 PF00557.19 EIE92443.1 - 1.8e-44 151.8 0.1 3.6e-44 150.8 0.1 1.5 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 EIE92443.1 - 0.0014 19.1 0.1 0.0055 17.1 0.0 2.1 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Glyco_trans_2_3 PF13632.1 EIE92445.1 - 1.2e-13 51.2 0.1 2.4e-13 50.2 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferase family group 2 DDE_Tnp_IS66_C PF13817.1 EIE92445.1 - 0.059 13.3 0.1 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 IS66 C-terminal element Asp PF00026.18 EIE92446.1 - 1.9e-79 267.2 0.1 2.4e-79 266.8 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIE92446.1 - 1.3e-07 31.6 0.4 3.7e-07 30.2 0.3 1.8 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EIE92446.1 - 0.0018 17.8 0.0 0.0061 16.1 0.0 1.9 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Meleagrin PF08189.6 EIE92446.1 - 0.14 11.6 0.4 0.27 10.7 0.2 1.4 1 0 0 1 1 1 0 Meleagrin/Cygnin family TrkH PF02386.11 EIE92447.1 - 2.5e-53 180.9 10.2 3e-53 180.6 7.1 1.0 1 0 0 1 1 1 1 Cation transport protein DUF4064 PF13273.1 EIE92447.1 - 0.04 14.0 2.3 0.097 12.7 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) zf-RVT PF13966.1 EIE92448.1 - 2.2e-06 27.8 1.8 3.3e-06 27.3 0.6 1.8 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase NurA PF09376.5 EIE92449.1 - 0.061 12.7 0.0 0.063 12.7 0.0 1.2 1 0 0 1 1 1 0 NurA domain M16C_assoc PF08367.6 EIE92450.1 - 1.9e-76 256.1 2.7 6.9e-76 254.3 0.7 2.4 3 0 0 3 3 3 1 Peptidase M16C associated Peptidase_M16_C PF05193.16 EIE92450.1 - 5.8e-29 101.0 0.4 2e-12 47.1 0.0 3.6 3 0 0 3 3 3 3 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EIE92450.1 - 2.2e-09 37.2 2.1 2.6e-08 33.7 0.0 3.5 4 1 1 5 5 5 1 Insulinase (Peptidase family M16) DUF2312 PF10073.4 EIE92450.1 - 0.039 13.2 3.9 0.036 13.4 0.3 2.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) Mito_carr PF00153.22 EIE92451.1 - 2.7e-51 171.2 0.4 1e-25 89.2 0.0 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein Elong-fact-P_C PF09285.6 EIE92452.1 - 3e-13 48.8 0.2 5e-13 48.1 0.1 1.4 1 0 0 1 1 1 1 Elongation factor P, C-terminal EFP PF01132.15 EIE92452.1 - 7.2e-07 28.7 0.1 1.4e-06 27.8 0.1 1.5 1 0 0 1 1 1 1 Elongation factor P (EF-P) OB domain tRNA-synt_1b PF00579.20 EIE92453.1 - 4.5e-22 78.5 0.0 2.6e-15 56.3 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (W and Y) CBS PF00571.23 EIE92454.1 - 1.4e-34 117.5 11.0 1.4e-08 34.3 0.0 5.5 5 0 0 5 5 5 4 CBS domain PB1 PF00564.19 EIE92454.1 - 3.9e-08 32.8 1.2 1.7e-07 30.8 0.8 2.2 1 1 0 1 1 1 1 PB1 domain HrpA_pilin PF09589.5 EIE92454.1 - 0.0082 16.5 0.0 0.26 11.7 0.0 3.0 3 1 0 3 3 3 1 HrpA pilus formation protein KaiC PF06745.8 EIE92454.1 - 0.021 13.9 0.8 0.47 9.5 0.0 2.4 2 0 0 2 2 2 0 KaiC LMWPc PF01451.16 EIE92455.1 - 6.8e-35 120.3 0.0 7.9e-35 120.1 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase DivIC PF04977.10 EIE92456.1 - 0.069 12.6 2.0 0.12 11.9 1.4 1.2 1 0 0 1 1 1 0 Septum formation initiator DUF4200 PF13863.1 EIE92456.1 - 0.17 11.8 0.8 3 7.8 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) SlyX PF04102.7 EIE92457.1 - 0.036 14.4 1.2 0.036 14.4 0.8 2.8 3 0 0 3 3 3 0 SlyX Mto2_bdg PF12808.2 EIE92457.1 - 0.21 11.7 12.5 0.12 12.5 1.2 2.9 3 0 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Spc24 PF08286.6 EIE92457.1 - 3.5 7.3 6.1 23 4.6 4.3 2.4 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 CK2S PF15011.1 EIE92459.1 - 0.07 12.9 0.0 0.16 11.7 0.0 1.5 2 0 0 2 2 2 0 Casein Kinase 2 substrate DDE_3 PF13358.1 EIE92460.1 - 4.6e-27 94.5 0.1 6.1e-27 94.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.14 EIE92460.1 - 0.0038 16.3 0.3 2 7.4 0.0 2.1 2 0 0 2 2 2 2 DDE superfamily endonuclease Rad60-SLD_2 PF13881.1 EIE92460.1 - 0.022 14.6 0.4 0.041 13.7 0.3 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like rve PF00665.21 EIE92460.1 - 0.11 12.5 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain Rtt102p PF09510.5 EIE92461.1 - 0.066 13.2 0.1 0.066 13.2 0.1 1.9 2 0 0 2 2 2 0 Rtt102p-like transcription regulator protein Zn_Tnp_IS1595 PF12760.2 EIE92461.1 - 0.13 12.1 1.0 0.24 11.2 0.7 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-CCHC_4 PF14392.1 EIE92461.1 - 0.42 10.3 6.8 1.4 8.5 0.6 3.0 3 0 0 3 3 3 0 Zinc knuckle Inhibitor_I10 PF12559.3 EIE92462.1 - 0.18 12.1 2.4 0.48 10.7 0.1 2.3 1 1 1 2 2 2 0 Serine endopeptidase inhibitors GlutR_dimer PF00745.15 EIE92463.1 - 0.023 14.6 0.1 0.39 10.6 0.0 2.4 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain DSPc PF00782.15 EIE92463.1 - 0.054 13.0 0.3 0.27 10.8 0.0 2.2 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain DDE_3 PF13358.1 EIE92464.1 - 4.6e-27 94.5 0.1 6.1e-27 94.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.14 EIE92464.1 - 0.0038 16.3 0.3 2 7.4 0.0 2.1 2 0 0 2 2 2 2 DDE superfamily endonuclease Rad60-SLD_2 PF13881.1 EIE92464.1 - 0.022 14.6 0.4 0.041 13.7 0.3 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like rve PF00665.21 EIE92464.1 - 0.11 12.5 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain RVT_1 PF00078.22 EIE92465.1 - 1.3e-05 24.6 0.0 3.8e-05 23.1 0.0 1.7 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CK2S PF15011.1 EIE92465.1 - 0.068 12.9 0.0 0.15 11.8 0.0 1.5 2 0 0 2 2 2 0 Casein Kinase 2 substrate Malate_synthase PF01274.17 EIE92467.1 - 0.0052 14.8 0.1 0.0058 14.7 0.0 1.1 1 0 0 1 1 1 1 Malate synthase DDE_3 PF13358.1 EIE92467.1 - 0.074 12.7 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 DDE superfamily endonuclease SNF2_N PF00176.18 EIE92468.1 - 3.7e-81 272.1 0.1 3.7e-81 272.1 0.1 2.5 3 0 0 3 3 3 1 SNF2 family N-terminal domain SLIDE PF09111.5 EIE92468.1 - 7.9e-42 141.7 2.8 7.9e-42 141.7 2.0 3.5 2 0 0 2 2 2 1 SLIDE Helicase_C PF00271.26 EIE92468.1 - 3.9e-17 61.8 0.0 1.3e-16 60.2 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HAND PF09110.6 EIE92468.1 - 5.5e-13 49.3 13.0 5.5e-13 49.3 9.0 5.5 3 2 1 4 4 4 1 HAND La PF05383.12 EIE92468.1 - 2.8e-10 39.8 0.2 8.7e-10 38.2 0.2 1.9 1 0 0 1 1 1 1 La domain RRM_1 PF00076.17 EIE92468.1 - 2.9e-07 30.0 0.2 9.2e-07 28.4 0.2 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIE92468.1 - 5.2e-06 26.3 0.1 2.2e-05 24.3 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DEAD PF00270.24 EIE92468.1 - 0.0001 21.8 0.0 0.00083 18.8 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Myb_DNA-binding PF00249.26 EIE92468.1 - 0.00014 21.8 0.2 0.04 13.9 0.0 3.6 3 0 0 3 3 3 1 Myb-like DNA-binding domain AAA_14 PF13173.1 EIE92468.1 - 0.026 14.4 6.1 0.06 13.2 0.0 3.5 3 1 0 3 3 3 0 AAA domain AAA_22 PF13401.1 EIE92468.1 - 0.047 13.8 0.3 0.4 10.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain Arrestin_N PF00339.24 EIE92469.1 - 3.1e-08 33.5 0.0 9.5e-08 31.9 0.0 1.7 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EIE92469.1 - 0.0011 19.0 0.6 0.0022 18.1 0.4 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain TPR_11 PF13414.1 EIE92470.1 - 7.8e-32 108.7 9.1 2.7e-16 58.9 0.1 5.4 3 2 2 5 5 5 5 TPR repeat DnaJ PF00226.26 EIE92470.1 - 4.7e-23 80.6 4.4 4.7e-23 80.6 3.0 2.6 2 0 0 2 2 2 1 DnaJ domain TPR_1 PF00515.23 EIE92470.1 - 1.6e-21 74.9 7.0 1.5e-05 24.3 0.0 7.1 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.12 EIE92470.1 - 1.3e-20 71.6 6.5 0.0022 17.7 0.0 7.8 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_16 PF13432.1 EIE92470.1 - 1.2e-17 64.1 0.1 4.9e-06 27.0 0.0 5.1 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_9 PF13371.1 EIE92470.1 - 1e-14 54.1 1.9 2e-05 24.3 0.0 4.9 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 EIE92470.1 - 1.1e-14 54.5 17.0 6.9e-05 23.0 0.0 5.6 5 1 2 7 7 6 4 Tetratricopeptide repeat TPR_17 PF13431.1 EIE92470.1 - 2.7e-14 52.1 4.6 0.00045 20.1 0.1 6.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 EIE92470.1 - 1.2e-12 47.2 0.5 0.22 12.2 0.0 6.7 4 3 4 8 8 7 3 Tetratricopeptide repeat TPR_8 PF13181.1 EIE92470.1 - 9.1e-11 40.7 8.0 0.0049 16.5 0.0 7.5 6 1 2 8 8 8 1 Tetratricopeptide repeat Apc3 PF12895.2 EIE92470.1 - 1.2e-09 38.1 16.0 0.0019 18.3 0.8 5.5 4 1 2 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EIE92470.1 - 8.6e-07 29.0 2.1 0.32 11.5 0.0 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.1 EIE92470.1 - 4.3e-06 26.5 12.5 0.061 13.2 0.1 5.2 5 1 1 6 6 5 3 Tetratricopeptide repeat TPR_20 PF14561.1 EIE92470.1 - 0.0001 22.3 7.4 0.3 11.2 0.2 5.5 2 2 0 3 3 3 1 Tetratricopeptide repeat DUF357 PF04010.8 EIE92470.1 - 0.0019 17.8 3.8 0.35 10.5 0.0 3.8 3 0 0 3 3 3 1 Protein of unknown function (DUF357) Fis1_TPR_C PF14853.1 EIE92470.1 - 0.0049 16.7 8.9 3.3 7.6 0.2 4.8 4 0 0 4 4 4 2 Fis1 C-terminal tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 EIE92470.1 - 0.009 16.2 4.1 0.022 14.9 0.0 3.0 2 1 2 4 4 4 1 Alkyl sulfatase dimerisation TPR_7 PF13176.1 EIE92470.1 - 0.032 14.0 3.1 21 5.2 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat SurA_N_2 PF13623.1 EIE92470.1 - 0.056 13.4 3.5 0.79 9.6 0.3 2.6 2 0 0 2 2 2 0 SurA N-terminal domain SHNi-TPR PF10516.4 EIE92470.1 - 0.11 11.7 1.1 3.3 7.0 0.0 3.7 4 0 0 4 4 4 0 SHNi-TPR RA PF00788.18 EIE92471.1 - 6e-18 65.1 0.1 5.6e-08 33.1 0.0 2.9 2 0 0 2 2 2 2 Ras association (RalGDS/AF-6) domain SH3_1 PF00018.23 EIE92471.1 - 4.6e-06 25.9 0.0 1.1e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EIE92471.1 - 0.0001 21.8 0.0 0.00025 20.5 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain DUF221 PF02714.10 EIE92472.1 - 3.2e-87 292.4 38.8 2.5e-60 204.0 13.1 3.0 3 0 0 3 3 3 2 Domain of unknown function DUF221 RSN1_TM PF13967.1 EIE92472.1 - 1.3e-36 125.5 8.6 1.3e-36 125.5 5.9 3.5 4 1 0 4 4 4 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EIE92472.1 - 2.7e-09 37.4 0.1 6.6e-09 36.1 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4463) Catalase PF00199.14 EIE92473.1 - 3.8e-152 506.4 0.4 4.9e-152 506.0 0.3 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EIE92473.1 - 6.6e-17 61.1 0.1 1.6e-16 59.9 0.0 1.7 2 0 0 2 2 2 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.19 EIE92473.1 - 0.013 14.9 0.0 0.046 13.1 0.0 1.9 2 0 0 2 2 2 0 DJ-1/PfpI family Ribosomal_L10 PF00466.15 EIE92475.1 - 7.3e-27 93.2 0.3 1.5e-26 92.2 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 EIE92475.1 - 1e-20 73.9 7.7 3.1e-20 72.3 3.7 2.3 2 0 0 2 2 2 1 60s Acidic ribosomal protein S19 PF06756.6 EIE92475.1 - 0.036 13.9 0.2 0.2 11.5 0.0 2.1 2 0 0 2 2 2 0 Chorion protein S19 C-terminal Fungal_trans PF04082.13 EIE92476.1 - 9e-31 106.6 0.2 9e-31 106.6 0.1 2.4 3 0 0 3 3 3 1 Fungal specific transcription factor domain CTP_transf_2 PF01467.21 EIE92478.1 - 4.1e-20 72.4 0.0 1e-13 51.5 0.0 2.3 2 0 0 2 2 2 2 Cytidylyltransferase ScdA_N PF04405.9 EIE92478.1 - 0.0079 15.5 0.0 0.023 14.0 0.0 1.7 1 0 0 1 1 1 1 Domain of Unknown function (DUF542) MOZ_SAS PF01853.13 EIE92479.1 - 1.2e-68 230.0 3.8 4.7e-46 156.4 2.5 2.2 2 0 0 2 2 2 2 MOZ/SAS family Acetyltransf_1 PF00583.19 EIE92479.1 - 0.014 15.4 0.0 0.028 14.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family zf-C2H2_jaz PF12171.3 EIE92479.1 - 0.015 15.4 0.2 0.015 15.4 0.1 2.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Acetyltransf_7 PF13508.1 EIE92479.1 - 0.071 13.2 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 EIE92479.1 - 0.079 12.7 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein Ribonuclease_T2 PF00445.13 EIE92480.1 - 1.6e-36 125.7 0.7 2.1e-36 125.3 0.5 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family Mtf2_C PF14061.1 EIE92480.1 - 0.034 14.0 0.0 0.078 12.8 0.0 1.5 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 Na_trans_assoc PF06512.8 EIE92481.1 - 4 7.3 14.3 4.6 7.1 9.9 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated UAA PF08449.6 EIE92482.1 - 2.2e-12 46.5 13.1 3.7e-12 45.7 9.1 1.3 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 EIE92482.1 - 3.7e-10 39.9 21.5 8.4e-06 25.8 3.1 2.8 2 1 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.10 EIE92482.1 - 5.8e-10 38.6 1.2 5.8e-10 38.6 0.9 1.6 1 1 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.11 EIE92482.1 - 0.00024 20.7 22.2 0.0024 17.5 6.2 2.8 3 0 0 3 3 3 2 Triose-phosphate Transporter family EmrE PF13536.1 EIE92482.1 - 0.0039 17.3 1.6 0.0039 17.3 1.1 2.8 3 0 0 3 3 3 1 Multidrug resistance efflux transporter DUF914 PF06027.7 EIE92482.1 - 0.076 11.8 13.9 0.34 9.6 9.7 1.9 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF914) UPF0546 PF10639.4 EIE92482.1 - 2 8.2 7.6 0.52 10.1 0.3 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0546 RRM_6 PF14259.1 EIE92483.1 - 0.0011 18.8 0.0 0.0019 18.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Ribosomal_S5 PF00333.15 EIE92484.1 - 2.6e-28 97.5 1.6 5.1e-28 96.6 1.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 EIE92484.1 - 2.4e-22 77.9 0.0 4.1e-22 77.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Pkinase PF00069.20 EIE92485.1 - 1.1e-70 237.7 0.0 2.1e-70 236.8 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIE92485.1 - 5.2e-37 127.3 0.0 8e-37 126.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIE92485.1 - 0.00098 18.1 0.0 0.0017 17.4 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 EIE92485.1 - 0.02 13.9 0.0 0.044 12.8 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EI24 PF07264.6 EIE92486.1 - 1.9e-12 47.0 23.2 2.6e-12 46.6 16.1 1.1 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Tetraspannin PF00335.15 EIE92487.1 - 3e-08 33.2 1.4 4.3e-08 32.6 1.0 1.2 1 0 0 1 1 1 1 Tetraspanin family Mpv17_PMP22 PF04117.7 EIE92487.1 - 0.11 12.2 2.8 0.62 9.7 0.2 2.5 2 1 0 2 2 2 0 Mpv17 / PMP22 family TPR_1 PF00515.23 EIE92488.1 - 5e-50 165.1 39.2 1.9e-08 33.5 0.0 11.1 10 2 1 11 11 11 9 Tetratricopeptide repeat TPR_11 PF13414.1 EIE92488.1 - 9.6e-46 153.3 28.7 3e-12 46.0 0.3 6.6 2 1 5 7 7 7 7 TPR repeat TPR_2 PF07719.12 EIE92488.1 - 5.9e-45 147.6 35.3 6.7e-06 25.6 0.0 10.3 10 1 0 10 10 9 8 Tetratricopeptide repeat TPR_17 PF13431.1 EIE92488.1 - 4.7e-33 110.6 27.1 0.00014 21.7 0.1 9.7 10 0 0 10 10 9 7 Tetratricopeptide repeat TPR_12 PF13424.1 EIE92488.1 - 9.7e-33 111.9 28.6 5.8e-08 32.5 0.6 5.7 2 2 4 6 6 6 6 Tetratricopeptide repeat TPR_16 PF13432.1 EIE92488.1 - 5.5e-31 106.5 17.1 7.9e-09 35.9 0.1 6.7 3 1 4 7 7 7 7 Tetratricopeptide repeat TPR_8 PF13181.1 EIE92488.1 - 6e-29 97.6 35.7 1.2e-05 24.7 2.1 9.4 7 2 2 9 9 9 8 Tetratricopeptide repeat TPR_14 PF13428.1 EIE92488.1 - 9.2e-27 91.1 15.1 0.0011 19.3 0.0 8.6 2 2 6 8 8 8 8 Tetratricopeptide repeat TPR_19 PF14559.1 EIE92488.1 - 7.1e-26 90.3 18.7 5.4e-06 26.6 0.4 7.2 3 2 5 8 8 8 6 Tetratricopeptide repeat TPR_7 PF13176.1 EIE92488.1 - 3.1e-20 70.2 24.3 0.0021 17.7 0.4 9.5 8 2 0 8 8 8 5 Tetratricopeptide repeat TPR_6 PF13174.1 EIE92488.1 - 1.4e-17 62.8 31.7 0.021 15.2 0.3 9.4 9 1 0 9 9 9 4 Tetratricopeptide repeat TPR_9 PF13371.1 EIE92488.1 - 1.5e-14 53.5 15.6 0.00058 19.6 0.4 6.5 1 1 6 7 7 7 5 Tetratricopeptide repeat Apc3 PF12895.2 EIE92488.1 - 2e-10 40.6 25.2 2.3e-06 27.6 2.7 4.8 2 1 4 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 EIE92488.1 - 1.8e-09 37.0 15.5 0.00027 20.1 1.1 4.4 1 1 3 4 4 4 3 Tetratricopeptide repeat SNAP PF14938.1 EIE92488.1 - 1.6e-07 30.8 21.4 0.003 16.7 4.8 3.7 2 2 1 3 3 3 3 Soluble NSF attachment protein, SNAP TPR_20 PF14561.1 EIE92488.1 - 7e-06 26.0 3.1 0.59 10.2 0.0 5.7 4 3 3 7 7 6 1 Tetratricopeptide repeat TPR_10 PF13374.1 EIE92488.1 - 0.00075 19.3 27.6 0.02 14.8 0.1 7.3 7 0 0 7 7 7 1 Tetratricopeptide repeat ChAPs PF09295.5 EIE92488.1 - 0.011 14.4 4.9 0.43 9.2 0.2 3.0 2 1 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) MIT PF04212.13 EIE92488.1 - 0.012 15.4 24.0 2.5 8.0 0.8 6.2 6 2 0 6 6 6 0 MIT (microtubule interacting and transport) domain DUF627 PF04781.7 EIE92488.1 - 0.028 14.0 0.5 7.4 6.2 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF627) TOM20_plant PF06552.7 EIE92488.1 - 0.03 13.9 6.8 7.2 6.1 0.0 4.8 1 1 5 6 6 6 0 Plant specific mitochondrial import receptor subunit TOM20 Tcf25 PF04910.9 EIE92488.1 - 0.041 12.8 5.5 0.24 10.2 0.0 3.0 2 1 1 3 3 3 0 Transcriptional repressor TCF25 TPR_3 PF07720.7 EIE92488.1 - 0.093 12.5 17.0 4.9 7.0 0.5 6.1 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_21 PF09976.4 EIE92488.1 - 0.098 12.5 18.7 0.94 9.4 1.0 4.9 4 2 1 5 5 5 0 Tetratricopeptide repeat RPN7 PF10602.4 EIE92488.1 - 0.16 11.3 9.9 6.2 6.1 0.0 5.0 5 1 1 6 6 6 0 26S proteasome subunit RPN7 Fis1_TPR_C PF14853.1 EIE92488.1 - 0.17 11.7 9.3 29 4.6 0.0 5.7 5 1 1 6 6 5 0 Fis1 C-terminal tetratricopeptide repeat TPPII_N PF12583.3 EIE92488.1 - 0.19 11.8 1.6 25 4.9 0.1 3.2 3 0 0 3 3 3 0 Tripeptidyl peptidase II N terminal Coatomer_WDAD PF04053.9 EIE92488.1 - 0.59 8.8 10.5 7.3 5.2 2.0 4.0 3 1 0 3 3 3 0 Coatomer WD associated region BTAD PF03704.12 EIE92488.1 - 1.8 8.8 11.4 5.8 7.1 0.8 3.1 2 1 1 3 3 3 0 Bacterial transcriptional activator domain PAP2 PF01569.16 EIE92490.1 - 2e-08 33.9 4.4 0.00096 18.8 1.5 2.9 2 1 1 3 3 3 2 PAP2 superfamily DUF212 PF02681.9 EIE92490.1 - 0.0071 16.0 0.2 0.098 12.3 0.0 2.4 1 1 1 2 2 2 1 Divergent PAP2 family PUF PF00806.14 EIE92491.1 - 6.5e-42 138.6 12.5 3.9e-08 32.3 0.4 6.2 6 0 0 6 6 6 6 Pumilio-family RNA binding repeat MgtE_N PF03448.12 EIE92491.1 - 0.06 13.6 0.0 0.27 11.5 0.0 2.0 3 0 0 3 3 3 0 MgtE intracellular N domain SYCE1 PF15233.1 EIE92493.1 - 0.0079 16.1 0.3 0.012 15.4 0.2 1.2 1 0 0 1 1 1 1 Synaptonemal complex central element protein 1 DUF972 PF06156.8 EIE92493.1 - 0.024 14.9 0.7 0.04 14.2 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Cluap1 PF10234.4 EIE92493.1 - 0.025 13.7 0.3 0.036 13.2 0.2 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 TBPIP PF07106.8 EIE92493.1 - 0.033 13.7 0.2 0.052 13.0 0.2 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF3450 PF11932.3 EIE92493.1 - 0.057 12.6 0.4 0.089 12.0 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) SNAPc19 PF15497.1 EIE92493.1 - 0.059 13.5 0.3 0.11 12.6 0.2 1.4 1 0 0 1 1 1 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 DDE_3 PF13358.1 EIE92494.1 - 4.3e-21 75.2 0.4 5.9e-21 74.7 0.3 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease RVT_1 PF00078.22 EIE92496.1 - 0.00024 20.5 0.0 0.00026 20.4 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Band_7 PF01145.20 EIE92498.1 - 1.8e-24 86.5 5.5 2.3e-24 86.2 3.5 1.4 1 1 0 1 1 1 1 SPFH domain / Band 7 family DUF2884 PF11101.3 EIE92498.1 - 0.033 13.5 2.2 0.035 13.4 0.6 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2884) DUF1378 PF07125.6 EIE92498.1 - 0.28 11.1 1.3 12 5.9 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1378) MgtE_N PF03448.12 EIE92498.1 - 0.28 11.5 3.1 16 5.8 0.0 2.3 2 0 0 2 2 2 0 MgtE intracellular N domain DUF3811 PF11656.3 EIE92498.1 - 0.31 11.1 3.4 0.42 10.7 1.5 1.8 1 1 1 2 2 2 0 YjbD family (DUF3811) PC-Esterase PF13839.1 EIE92499.1 - 0.005 16.6 0.0 0.0074 16.1 0.0 1.2 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p IP_trans PF02121.13 EIE92501.1 - 1.7e-85 286.2 7.9 2.3e-47 161.3 0.8 2.0 1 1 1 2 2 2 2 Phosphatidylinositol transfer protein Polysacc_deac_1 PF01522.16 EIE92502.1 - 3.6e-23 81.5 0.0 6.8e-23 80.6 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase ORF6C PF10552.4 EIE92502.1 - 0.035 13.8 0.1 0.074 12.7 0.0 1.5 1 0 0 1 1 1 0 ORF6C domain Mgm101p PF06420.7 EIE92503.1 - 1.1e-91 304.7 0.0 1.6e-91 304.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 Methyltransf_3 PF01596.12 EIE92504.1 - 6.2e-36 123.3 0.1 1.1e-26 93.1 0.0 2.1 1 1 1 2 2 2 2 O-methyltransferase Methyltransf_18 PF12847.2 EIE92504.1 - 8.4e-05 23.1 0.0 0.00018 22.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.14 EIE92504.1 - 0.00015 21.3 0.0 0.00023 20.7 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.1 EIE92504.1 - 0.0004 21.1 0.0 0.0028 18.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIE92504.1 - 0.0035 17.3 0.0 0.0057 16.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIE92504.1 - 0.086 12.4 0.0 0.29 10.7 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain MFS_1 PF07690.11 EIE92505.1 - 3.4e-05 22.7 0.9 4.8e-05 22.2 0.6 1.3 1 1 1 2 2 2 1 Major Facilitator Superfamily Acyl_transf_3 PF01757.17 EIE92505.1 - 0.00024 20.0 2.4 0.00029 19.7 1.7 1.0 1 0 0 1 1 1 1 Acyltransferase family MFS_1 PF07690.11 EIE92506.1 - 0.047 12.3 18.2 0.053 12.2 12.6 1.0 1 0 0 1 1 1 0 Major Facilitator Superfamily FUSC_2 PF13515.1 EIE92506.1 - 0.7 9.8 11.1 1.4 8.8 7.5 1.6 1 1 0 1 1 1 0 Fusaric acid resistance protein-like DRAT PF07357.6 EIE92508.1 - 0.02 14.1 0.1 0.046 12.9 0.1 1.7 1 0 0 1 1 1 0 Dinitrogenase reductase ADP-ribosyltransferase (DRAT) Band_7 PF01145.20 EIE92508.1 - 0.043 13.7 0.4 0.061 13.2 0.3 1.3 1 0 0 1 1 1 0 SPFH domain / Band 7 family BssS PF13991.1 EIE92508.1 - 0.052 13.2 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 BssS protein family Imm20 PF15568.1 EIE92508.1 - 0.068 13.0 0.1 2.7 7.8 0.0 2.5 2 1 0 2 2 2 0 Immunity protein 20 Cyclin PF08613.6 EIE92509.1 - 8.3e-18 65.2 0.9 1.4e-17 64.5 0.6 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EIE92509.1 - 7.6e-08 31.9 0.7 1.5e-07 30.9 0.5 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF896 PF05979.7 EIE92509.1 - 0.0042 16.6 2.1 0.0087 15.6 1.5 1.5 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF896) EF-hand_4 PF12763.2 EIE92510.1 - 1.1e-27 95.8 0.0 4.4e-17 61.7 0.0 2.5 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 EIE92510.1 - 0.00021 21.3 0.0 0.002 18.1 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EIE92510.1 - 0.0071 15.5 0.3 0.037 13.3 0.0 2.4 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 EIE92510.1 - 0.033 14.0 0.0 1.5 8.9 0.0 2.7 2 0 0 2 2 2 0 EF-hand domain FlgH PF02107.11 EIE92511.1 - 1 8.8 11.5 1.6 8.3 8.0 1.2 1 0 0 1 1 1 0 Flagellar L-ring protein MFS_1 PF07690.11 EIE92512.1 - 1.8e-21 76.2 12.4 3.3e-21 75.3 8.7 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIE92512.1 - 4.5e-10 38.6 0.3 5e-10 38.5 0.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 EIE92512.1 - 0.016 13.4 0.1 0.018 13.2 0.1 1.1 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 EIE92512.1 - 0.059 11.4 2.0 0.11 10.5 1.4 1.4 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family HK PF02110.10 EIE92513.1 - 2.4e-83 279.0 1.4 3.7e-83 278.4 1.0 1.3 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.12 EIE92513.1 - 3e-62 208.9 0.9 2e-61 206.2 0.1 2.1 2 0 0 2 2 2 1 Thiamine monophosphate synthase/TENI Phos_pyr_kin PF08543.7 EIE92513.1 - 3.3e-05 23.2 0.1 0.00011 21.5 0.0 1.8 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase Phos_pyr_kin PF08543.7 EIE92514.1 - 3.4e-86 288.4 0.8 5e-86 287.9 0.5 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 EIE92514.1 - 9e-35 120.3 0.4 8.3e-34 117.1 0.0 2.0 1 1 1 2 2 2 1 TENA/THI-4/PQQC family PfkB PF00294.19 EIE92514.1 - 1.3e-06 27.7 0.1 2.3e-06 26.9 0.1 1.3 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Tenui_PVC2 PF06656.6 EIE92514.1 - 0.039 11.7 0.1 0.057 11.2 0.1 1.1 1 0 0 1 1 1 0 Tenuivirus PVC2 protein EF-hand_1 PF00036.27 EIE92515.1 - 4.9e-18 62.9 4.4 1.6e-08 33.2 0.0 2.7 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 EIE92515.1 - 2e-15 56.6 0.3 3.3e-15 55.9 0.2 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EIE92515.1 - 1.7e-14 52.3 5.2 3.1e-09 35.9 0.1 3.0 2 1 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.1 EIE92515.1 - 2.2e-13 48.8 2.6 4.6e-07 28.8 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 EIE92515.1 - 9.4e-12 44.3 5.0 2.3e-08 33.4 0.2 2.4 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_9 PF14658.1 EIE92515.1 - 3.3e-06 26.9 0.0 4.3e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain EF-hand_4 PF12763.2 EIE92515.1 - 0.00013 21.6 0.2 0.00016 21.3 0.1 1.1 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand UPF0154 PF03672.8 EIE92515.1 - 0.026 14.1 0.0 0.1 12.2 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) Imm16 PF15565.1 EIE92515.1 - 0.036 13.9 0.7 2.3 8.1 0.0 2.1 1 1 1 2 2 2 0 Immunity protein 16 DUF2623 PF11115.3 EIE92515.1 - 0.069 13.0 0.0 0.08 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2623) SPARC_Ca_bdg PF10591.4 EIE92515.1 - 0.14 12.2 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region RSS_P20 PF11757.3 EIE92515.1 - 0.16 12.0 0.2 0.21 11.6 0.1 1.3 1 0 0 1 1 1 0 Suppressor of RNA silencing P21-like MT-A70 PF05063.9 EIE92517.1 - 5e-13 48.9 0.3 1.1e-12 47.9 0.2 1.5 1 0 0 1 1 1 1 MT-A70 DUF433 PF04255.9 EIE92517.1 - 0.086 12.2 0.0 0.29 10.6 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF433) NIF PF03031.13 EIE92518.1 - 6.9e-54 181.8 0.2 1e-53 181.2 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Cys_rich_VLP PF14194.1 EIE92518.1 - 0.014 15.0 0.0 3 7.6 0.0 2.3 2 0 0 2 2 2 0 Cysteine-rich VLP HAD_2 PF13419.1 EIE92518.1 - 0.14 12.3 0.2 1.5 9.0 0.0 2.1 1 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase SET PF00856.23 EIE92519.1 - 1.2e-09 38.7 0.4 1.7e-07 31.6 0.0 3.1 3 1 0 3 3 3 2 SET domain API5 PF05918.6 EIE92520.1 - 0.0033 15.9 1.5 0.0047 15.5 0.7 1.4 2 0 0 2 2 2 1 Apoptosis inhibitory protein 5 (API5) DUF1888 PF08985.6 EIE92520.1 - 0.089 12.4 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1888) DUF2743 PF10899.3 EIE92520.1 - 0.1 11.9 2.3 0.6 9.4 0.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2743) AA_permease_2 PF13520.1 EIE92523.1 - 1.9e-23 82.6 17.6 1.3e-13 50.3 2.4 3.0 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.16 EIE92523.1 - 4.8e-11 41.6 14.9 5e-10 38.3 1.3 2.1 1 1 1 2 2 2 2 Amino acid permease TraQ PF09679.5 EIE92523.1 - 0.025 14.5 0.4 0.073 13.0 0.0 1.9 2 0 0 2 2 2 0 Type-F conjugative transfer system pilin chaperone (TraQ) Ank_2 PF12796.2 EIE92524.1 - 6.3e-39 132.2 7.5 4.3e-13 49.4 0.1 3.3 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 EIE92524.1 - 4.7e-24 82.9 1.8 3e-05 23.6 0.0 6.6 7 0 0 7 7 7 4 Ankyrin repeat Ank_4 PF13637.1 EIE92524.1 - 8.1e-20 70.8 0.2 1.3e-07 31.8 0.0 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIE92524.1 - 7e-17 59.8 2.1 0.00016 21.6 0.0 5.7 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 EIE92524.1 - 5.1e-16 58.3 1.0 2e-05 24.6 0.0 4.1 3 1 1 4 4 4 3 Ankyrin repeats (many copies) zf-AN1 PF01428.11 EIE92525.1 - 1.3e-10 40.9 7.8 1.3e-10 40.9 5.4 1.9 2 0 0 2 2 2 1 AN1-like Zinc finger Caudo_TAP PF02413.12 EIE92525.1 - 0.00017 21.7 0.1 0.00023 21.3 0.1 1.2 1 0 0 1 1 1 1 Caudovirales tail fibre assembly protein IBR PF01485.16 EIE92525.1 - 0.2 11.5 15.7 1.3 8.9 10.9 2.5 1 1 0 1 1 1 0 IBR domain Methyltransf_FA PF12248.3 EIE92526.1 - 0.034 14.1 0.0 0.057 13.4 0.0 1.3 1 0 0 1 1 1 0 Farnesoic acid 0-methyl transferase TRI12 PF06609.8 EIE92527.1 - 0.034 12.3 0.0 0.045 11.9 0.0 1.1 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) WD40 PF00400.27 EIE92529.1 - 5.1e-63 206.8 30.1 7e-10 38.3 0.6 12.9 12 1 0 12 12 12 11 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EIE92529.1 - 0.0012 17.7 0.1 0.045 12.5 0.1 2.6 2 0 0 2 2 2 1 Nup133 N terminal like BBS2_Mid PF14783.1 EIE92529.1 - 0.0088 15.8 0.0 5.5 6.8 0.0 4.0 4 0 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region Ribosomal_L2_C PF03947.13 EIE92530.1 - 3.4e-42 143.3 2.3 3.4e-42 143.3 1.6 1.5 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EIE92530.1 - 1.8e-15 56.6 0.1 4.4e-15 55.4 0.1 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain DUF1604 PF07713.8 EIE92531.1 - 8.4e-38 128.0 1.9 8.4e-38 128.0 1.3 3.7 2 1 0 2 2 2 1 Protein of unknown function (DUF1604) G-patch PF01585.18 EIE92531.1 - 5.1e-08 32.5 0.1 1.9e-07 30.7 0.0 2.0 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EIE92531.1 - 0.019 14.7 0.3 0.019 14.7 0.2 4.6 5 1 0 5 5 5 0 DExH-box splicing factor binding site DUF1509 PF07420.6 EIE92531.1 - 5.3 6.2 27.0 3.8 6.7 17.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1509) vATP-synt_E PF01991.13 EIE92532.1 - 3e-56 189.8 8.7 3.5e-56 189.6 6.0 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit SAGA-Tad1 PF12767.2 EIE92533.1 - 3e-08 33.6 0.0 3e-08 33.6 0.0 1.0 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit p450 PF00067.17 EIE92534.1 - 2.7e-96 322.8 0.1 3.8e-96 322.4 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.15 EIE92534.1 - 1.1e-36 126.4 0.0 1.8e-36 125.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EIE92534.1 - 4.9e-23 81.7 0.8 1.3e-22 80.3 0.5 1.8 1 1 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 EIE92534.1 - 2.1e-16 60.4 0.0 5e-16 59.2 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain HSF_DNA-bind PF00447.12 EIE92538.1 - 1.3e-33 115.2 1.1 3.8e-33 113.7 0.8 1.8 1 0 0 1 1 1 1 HSF-type DNA-binding ATP-grasp_4 PF13535.1 EIE92539.1 - 0.0018 18.0 0.0 0.0035 17.0 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.17 EIE92539.1 - 0.086 12.1 0.0 2.2 7.6 0.0 2.5 3 0 0 3 3 3 0 ATP-grasp domain MFS_1 PF07690.11 EIE92540.1 - 1.9e-33 115.6 12.5 2.3e-33 115.3 8.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIE92540.1 - 1.9e-06 26.7 12.3 4.1e-06 25.6 8.4 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter DUF1228 PF06779.9 EIE92540.1 - 0.0027 17.7 0.5 0.0027 17.7 0.4 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1228) DUF4231 PF14015.1 EIE92540.1 - 0.19 11.7 2.0 3.2 7.7 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) DUF3753 PF12575.3 EIE92540.1 - 0.25 11.1 3.8 3.8 7.3 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) Na_Pi_cotrans PF02690.10 EIE92540.1 - 0.67 9.6 6.1 0.2 11.3 0.8 2.2 2 0 0 2 2 2 0 Na+/Pi-cotransporter DUF443 PF04276.7 EIE92542.1 - 0.014 14.8 0.7 0.014 14.8 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF443) Gaa1 PF04114.9 EIE92543.1 - 1.3e-51 175.9 0.0 1.3e-51 175.9 0.0 2.9 2 1 0 2 2 2 1 Gaa1-like, GPI transamidase component Methyltransf_23 PF13489.1 EIE92544.1 - 2.4e-11 43.6 0.0 5e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIE92544.1 - 3.6e-11 43.3 0.0 8.6e-11 42.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIE92544.1 - 3.1e-08 33.8 0.0 9.8e-08 32.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 EIE92544.1 - 2.4e-07 30.0 0.1 1.9e-05 23.8 0.0 2.9 3 0 0 3 3 3 1 Putative methyltransferase Ubie_methyltran PF01209.13 EIE92544.1 - 6.8e-07 28.6 0.0 2e-06 27.1 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EIE92544.1 - 8.3e-07 28.7 0.0 3.4e-06 26.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIE92544.1 - 1.3e-06 28.8 0.0 3.3e-06 27.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIE92544.1 - 2.8e-06 27.8 0.0 1.9e-05 25.2 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EIE92544.1 - 0.008 15.5 0.0 0.17 11.2 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase small domain FtsJ PF01728.14 EIE92544.1 - 0.013 15.5 0.0 0.12 12.3 0.0 2.2 2 0 0 2 2 2 0 FtsJ-like methyltransferase Methyltransf_8 PF05148.10 EIE92544.1 - 0.015 14.9 0.0 0.045 13.3 0.0 1.8 2 1 0 2 2 2 0 Hypothetical methyltransferase Nucleocapsid-N PF11030.3 EIE92545.1 - 0.13 12.0 0.1 0.16 11.7 0.1 1.2 1 0 0 1 1 1 0 Nucleocapsid protein N Lsm_interact PF05391.6 EIE92547.1 - 0.00011 21.4 0.3 0.00027 20.2 0.2 1.7 1 0 0 1 1 1 1 Lsm interaction motif eIF3_N PF09440.5 EIE92547.1 - 0.011 15.8 4.3 0.021 14.9 3.0 1.5 1 0 0 1 1 1 0 eIF3 subunit 6 N terminal domain TPR_14 PF13428.1 EIE92547.1 - 0.016 15.7 0.0 0.1 13.2 0.0 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 EIE92547.1 - 0.04 14.6 0.0 0.1 13.3 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat U3_assoc_6 PF08640.6 EIE92547.1 - 0.099 12.4 0.1 0.099 12.4 0.1 3.1 3 1 0 3 3 3 0 U3 small nucleolar RNA-associated protein 6 DUF3987 PF13148.1 EIE92547.1 - 1.8 7.0 9.0 2.7 6.4 6.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Peptidase_S49_N PF08496.5 EIE92547.1 - 2.9 7.6 7.7 5.6 6.7 5.3 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal RAB3GAP2_N PF14655.1 EIE92548.1 - 6.5e-46 157.1 0.0 1e-44 153.1 0.0 2.3 1 1 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus HELP PF03451.9 EIE92549.1 - 0.13 11.8 0.1 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 HELP motif DDE_3 PF13358.1 EIE92551.1 - 8.1e-10 38.6 0.6 1.5e-05 24.7 0.5 2.6 2 1 1 3 3 3 2 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE92551.1 - 1.3e-08 34.7 0.9 2.3e-08 33.9 0.5 1.5 1 1 0 1 1 1 1 Transposase Exo_endo_phos PF03372.18 EIE92552.1 - 3e-14 53.5 1.7 6.5e-14 52.4 1.2 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EIE92552.1 - 4.3e-06 26.3 0.4 1.2e-05 24.8 0.1 2.0 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Cytochrome_C554 PF13435.1 EIE92552.1 - 0.0031 17.5 4.0 0.0084 16.1 2.8 1.6 1 0 0 1 1 1 1 Cytochrome c554 and c-prime zf-CCHC PF00098.18 EIE92552.1 - 0.0058 16.5 4.4 0.0058 16.5 3.0 2.5 2 0 0 2 2 2 1 Zinc knuckle Transferase PF02458.10 EIE92553.1 - 0.054 11.9 0.0 0.061 11.7 0.0 1.0 1 0 0 1 1 1 0 Transferase family DUF569 PF04601.8 EIE92554.1 - 0.0046 16.3 0.2 0.018 14.4 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF569) HTH_12 PF08461.5 EIE92554.1 - 0.026 14.2 0.0 0.048 13.4 0.0 1.4 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain HTH_26 PF13443.1 EIE92554.1 - 0.12 12.5 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain DDE_3 PF13358.1 EIE92556.1 - 3.5e-20 72.2 0.0 4.1e-20 72.0 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE92556.1 - 0.033 14.3 0.0 0.067 13.3 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain Mod_r PF07200.8 EIE92557.1 - 0.035 14.0 0.1 0.066 13.1 0.1 1.4 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Matrilin_ccoil PF10393.4 EIE92557.1 - 0.066 12.5 0.3 0.14 11.5 0.2 1.5 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin Med9 PF07544.8 EIE92557.1 - 0.066 12.9 0.1 0.14 11.8 0.1 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Reo_sigmaC PF04582.7 EIE92557.1 - 0.12 11.5 0.9 0.18 10.9 0.6 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF904 PF06005.7 EIE92557.1 - 0.21 11.9 2.2 0.42 10.9 0.9 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF904) DivIC PF04977.10 EIE92557.1 - 0.21 11.0 0.8 0.41 10.1 0.5 1.5 1 0 0 1 1 1 0 Septum formation initiator DUF765 PF05570.6 EIE92558.1 - 5 7.1 6.6 15 5.6 4.6 2.0 1 1 0 1 1 1 0 Circovirus protein of unknown function (DUF765) RVT_1 PF00078.22 EIE92560.1 - 6e-16 58.4 0.3 1.7e-15 57.0 0.2 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 EIE92560.1 - 1.1e-05 25.8 0.0 2.5e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 EIE92560.1 - 3.9e-05 23.5 0.3 0.00012 21.9 0.2 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease F_actin_bind PF08919.5 EIE92560.1 - 0.0094 15.6 0.3 0.092 12.4 0.0 2.8 3 0 0 3 3 3 1 F-actin binding TPX2 PF06886.6 EIE92561.1 - 1.2 9.2 4.0 0.88 9.6 0.2 2.4 2 0 0 2 2 2 0 Targeting protein for Xklp2 (TPX2) RVT_1 PF00078.22 EIE92562.1 - 8.7e-31 106.9 0.2 1.5e-30 106.1 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 EIE92562.1 - 3.4e-06 27.4 0.0 9.1e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.5 EIE92562.1 - 6.1e-05 22.5 0.1 0.00012 21.6 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease Spuma_A9PTase PF03539.9 EIE92562.1 - 0.00013 21.9 0.4 0.00046 20.1 0.1 2.1 2 0 0 2 2 2 1 Spumavirus aspartic protease (A9) gag-asp_proteas PF13975.1 EIE92562.1 - 0.00021 21.0 0.0 0.00051 19.8 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 EIE92562.1 - 0.056 13.3 0.0 0.22 11.4 0.0 2.0 1 0 0 1 1 1 0 Retroviral aspartyl protease rve PF00665.21 EIE92563.1 - 2.8e-20 72.6 0.0 1.1e-19 70.7 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 EIE92563.1 - 7.4e-10 38.5 0.2 2.6e-09 36.7 0.2 1.9 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 EIE92563.1 - 9.7e-07 29.2 0.1 1e-05 25.9 0.1 2.4 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.15 EIE92563.1 - 1.3e-05 25.0 0.1 3.5e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EIE92563.1 - 0.00012 21.8 0.0 0.00027 20.6 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.5 EIE92563.1 - 0.063 12.8 0.0 0.23 11.0 0.0 2.0 1 0 0 1 1 1 0 Aspartyl protease DDE_Tnp_IS1595 PF12762.2 EIE92564.1 - 1.2e-06 28.4 0.2 1.4e-06 28.1 0.1 1.1 1 0 0 1 1 1 1 ISXO2-like transposase domain FimH_man-bind PF09160.5 EIE92564.1 - 0.051 13.4 0.0 0.055 13.2 0.0 1.1 1 0 0 1 1 1 0 FimH, mannose binding DDE_3 PF13358.1 EIE92565.1 - 1.6e-20 73.3 0.0 2.8e-20 72.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE92565.1 - 0.00037 20.4 1.8 0.00043 20.2 0.3 1.9 2 0 0 2 2 2 1 Transposase Sigma70_r1_2 PF00140.15 EIE92565.1 - 0.0054 16.3 0.1 0.012 15.3 0.1 1.6 1 0 0 1 1 1 1 Sigma-70 factor, region 1.2 DDE_3 PF13358.1 EIE92566.1 - 0.044 13.5 0.0 0.046 13.4 0.0 1.0 1 0 0 1 1 1 0 DDE superfamily endonuclease RVT_1 PF00078.22 EIE92568.1 - 1.6e-26 93.0 0.2 3.1e-26 92.0 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_C80 PF11713.3 EIE92570.1 - 0.054 13.3 1.0 2.5 7.8 0.1 2.2 1 1 1 2 2 2 0 Peptidase C80 family CBM_2 PF00553.14 EIE92570.1 - 0.085 12.9 2.8 0.53 10.3 0.9 2.2 1 1 1 2 2 2 0 Cellulose binding domain DUF3060 PF11259.3 EIE92570.1 - 0.12 11.9 1.1 3 7.5 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3060) DDE_Tnp_IS1595 PF12762.2 EIE92571.1 - 1.5e-08 34.5 0.1 2.1e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 ISXO2-like transposase domain MRP-L27 PF09809.4 EIE92571.1 - 0.0033 17.0 0.1 0.0048 16.4 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 DDE_Tnp_IS1595 PF12762.2 EIE92572.1 - 2.2e-10 40.5 0.0 5.1e-05 23.1 0.0 2.6 1 1 1 2 2 2 2 ISXO2-like transposase domain Condensin2nSMC PF12422.3 EIE92572.1 - 0.13 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Condensin II non structural maintenance of chromosomes subunit DDE_3 PF13358.1 EIE92574.1 - 2.1e-21 76.2 0.0 4.3e-21 75.1 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE92574.1 - 1.1e-15 57.4 1.9 2.8e-15 56.1 0.3 2.3 3 0 0 3 3 2 1 Transposase HTH_29 PF13551.1 EIE92574.1 - 2.7e-06 27.4 0.2 8.6e-06 25.8 0.2 1.9 2 0 0 2 2 1 1 Winged helix-turn helix HTH_38 PF13936.1 EIE92574.1 - 1.2e-05 24.7 0.1 3.3e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.1 EIE92574.1 - 7.7e-05 22.2 0.1 0.0028 17.2 0.0 2.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.1 EIE92574.1 - 8.7e-05 23.2 2.8 0.02 15.6 0.1 3.7 4 0 0 4 4 3 1 Homeodomain-like domain Sigma70_r4_2 PF08281.7 EIE92574.1 - 0.00063 19.1 0.8 0.024 14.0 0.0 3.2 4 0 0 4 4 4 1 Sigma-70, region 4 HTH_28 PF13518.1 EIE92574.1 - 0.0013 18.6 0.0 0.0056 16.6 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_21 PF13276.1 EIE92574.1 - 0.0014 18.5 0.1 0.13 12.2 0.0 2.8 3 0 0 3 3 3 1 HTH-like domain HTH_7 PF02796.10 EIE92574.1 - 0.0022 17.7 1.1 0.1 12.4 0.0 2.8 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase rve PF00665.21 EIE92574.1 - 0.0063 16.6 0.0 0.02 14.9 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain LacI PF00356.16 EIE92574.1 - 0.018 14.6 1.7 2.8 7.6 0.2 2.7 3 0 0 3 3 3 0 Bacterial regulatory proteins, lacI family HTH_Tnp_4 PF13613.1 EIE92574.1 - 0.022 14.2 0.1 0.057 12.9 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease CPSase_L_D3 PF02787.14 EIE92574.1 - 0.06 13.1 0.0 0.14 11.8 0.0 1.6 2 0 0 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain HTH_36 PF13730.1 EIE92574.1 - 0.082 13.0 0.4 4.1 7.6 0.0 2.9 3 0 0 3 3 2 0 Helix-turn-helix domain Sigma70_r4 PF04545.11 EIE92574.1 - 0.1 11.9 0.2 0.79 9.0 0.0 2.6 4 0 0 4 4 4 0 Sigma-70, region 4 HTH_Tnp_ISL3 PF13542.1 EIE92574.1 - 0.17 11.0 2.8 8.4 5.6 0.0 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 HTH_17 PF12728.2 EIE92574.1 - 0.21 11.8 2.4 15 5.9 0.1 3.2 3 0 0 3 3 3 0 Helix-turn-helix domain Chromo PF00385.19 EIE92575.1 - 2.7e-11 42.9 0.4 6.1e-11 41.8 0.3 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain YcgR_2 PF12945.2 EIE92575.1 - 0.074 12.9 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Flagellar protein YcgR rve PF00665.21 EIE92576.1 - 3e-23 82.2 0.0 7.5e-23 80.9 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE92576.1 - 9e-16 57.8 0.3 2.1e-15 56.6 0.2 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE92576.1 - 4e-11 42.3 1.1 9.6e-11 41.1 0.7 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.12 EIE92576.1 - 0.00053 20.0 0.9 0.0024 17.9 0.6 2.2 1 0 0 1 1 1 1 Retrotransposon gag protein zf-H2C2 PF09337.5 EIE92576.1 - 0.0014 18.0 0.1 0.0041 16.4 0.1 1.9 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Asp_protease_2 PF13650.1 EIE92576.1 - 0.0054 17.1 0.2 0.014 15.9 0.2 1.8 1 0 0 1 1 1 1 Aspartyl protease rve_3 PF13683.1 EIE92576.1 - 0.0076 15.7 0.1 0.05 13.1 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain UBN2_2 PF14227.1 EIE92576.1 - 0.024 14.1 5.6 0.049 13.1 0.0 3.3 3 0 0 3 3 3 0 gag-polypeptide of LTR copia-type Asp_protease PF09668.5 EIE92576.1 - 0.04 13.4 0.1 0.12 11.9 0.1 1.8 1 1 0 1 1 1 0 Aspartyl protease UBN2 PF14223.1 EIE92576.1 - 0.059 13.1 0.1 0.22 11.3 0.1 2.0 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Retrotrans_gag PF03732.12 EIE92577.1 - 1.4e-08 34.6 0.2 3e-08 33.6 0.2 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.18 EIE92577.1 - 0.00058 19.6 1.3 0.001 18.8 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle DUF1789 PF08748.6 EIE92577.1 - 0.34 11.0 2.3 0.3 11.1 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1789) rve PF00665.21 EIE92578.1 - 2.9e-20 72.5 0.0 8.5e-20 71.0 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE92578.1 - 3.9e-11 42.7 0.3 8.2e-11 41.6 0.2 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE92578.1 - 2.1e-10 40.0 0.4 5.6e-10 38.7 0.3 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.12 EIE92578.1 - 9.3e-05 22.4 0.9 0.00037 20.5 0.1 2.4 2 0 0 2 2 2 1 Retrotransposon gag protein DUF1759 PF03564.10 EIE92579.1 - 7e-05 22.6 0.2 0.00011 22.0 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) Retrotrans_gag PF03732.12 EIE92579.1 - 0.0021 18.1 0.0 0.0045 17.0 0.0 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein DDE_3 PF13358.1 EIE92580.1 - 6e-18 64.9 0.1 1.4e-17 63.7 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE92580.1 - 5.4e-12 45.5 1.0 5.4e-12 45.5 0.7 2.2 3 0 0 3 3 3 1 Transposase HTH_29 PF13551.1 EIE92580.1 - 0.0002 21.4 0.7 0.0004 20.5 0.1 1.8 2 0 0 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.1 EIE92580.1 - 0.00094 18.7 0.1 0.0025 17.3 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_7 PF02796.10 EIE92580.1 - 0.0074 16.1 0.0 0.021 14.6 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_30 PF13556.1 EIE92580.1 - 0.021 14.3 0.0 0.17 11.4 0.0 2.1 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain HTH_38 PF13936.1 EIE92580.1 - 0.031 13.8 0.0 0.11 12.0 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain RecX PF02631.11 EIE92580.1 - 0.13 12.4 0.3 0.27 11.4 0.2 1.5 1 0 0 1 1 1 0 RecX family RVT_1 PF00078.22 EIE92581.1 - 3e-27 95.3 0.2 5.8e-27 94.4 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_3 PF13358.1 EIE92582.1 - 8.9e-14 51.4 0.0 1.4e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF2567 PF10821.3 EIE92582.1 - 0.0068 15.9 0.0 0.0094 15.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2567) RNA_pol_Rpb1_2 PF00623.15 EIE92586.1 - 1.9e-10 40.9 0.0 3.3e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 zf-DNA_Pol PF08996.5 EIE92586.1 - 0.11 11.8 0.2 3 7.1 0.0 2.2 2 0 0 2 2 2 0 DNA Polymerase alpha zinc finger DNA_pol_B PF00136.16 EIE92588.1 - 8.1e-36 123.7 0.0 5.4e-35 121.0 0.0 1.9 1 1 0 1 1 1 1 DNA polymerase family B RNA_pol_Rpb2_6 PF00562.23 EIE92588.1 - 1.3e-11 43.8 0.0 1e-08 34.3 0.0 2.4 2 0 0 2 2 2 2 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_7 PF04560.15 EIE92588.1 - 0.0086 16.3 0.2 0.023 14.9 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 Rep_4 PF05797.6 EIE92593.1 - 0.53 8.9 3.2 1.7 7.2 0.1 2.0 1 1 1 2 2 2 0 Yeast trans-acting factor (REP1/REP2) DDE_3 PF13358.1 EIE92596.1 - 8.4e-17 61.2 0.0 1.3e-16 60.6 0.0 1.4 1 1 0 1 1 1 1 DDE superfamily endonuclease HCBP_related PF06594.6 EIE92596.1 - 0.032 13.8 0.0 0.07 12.7 0.0 1.6 1 0 0 1 1 1 0 Haemolysin-type calcium binding protein related domain HTH_Tnp_Tc3_2 PF01498.13 EIE92597.1 - 3.7e-08 33.3 1.0 7.5e-08 32.3 0.5 1.8 2 0 0 2 2 2 1 Transposase DDE_Tnp_IS1595 PF12762.2 EIE92598.1 - 3.5e-18 65.8 2.4 2.2e-12 47.0 0.1 3.1 2 1 0 2 2 2 2 ISXO2-like transposase domain HTH_Tnp_Tc3_2 PF01498.13 EIE92599.1 - 0.0043 17.0 1.4 0.013 15.5 0.6 2.1 1 1 1 2 2 2 1 Transposase DUF1667 PF07892.6 EIE92599.1 - 0.13 11.9 1.2 0.72 9.5 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1667) DDE_Tnp_IS1595 PF12762.2 EIE92600.1 - 3.5e-18 65.8 2.4 2.2e-12 47.0 0.1 3.1 2 1 0 2 2 2 2 ISXO2-like transposase domain DUF3713 PF12506.3 EIE92601.1 - 0.00013 22.0 0.8 0.00033 20.7 0.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3713) TGS PF02824.16 EIE92601.1 - 0.0076 16.0 0.0 1.7 8.5 0.0 2.9 2 1 0 2 2 2 2 TGS domain DDE_3 PF13358.1 EIE92605.1 - 0.0036 17.0 0.0 0.0052 16.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EIE92606.1 - 1.4e-17 63.7 0.0 3.7e-17 62.4 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE92606.1 - 3.9e-09 36.4 0.7 1.7e-08 34.4 0.7 2.0 2 1 0 2 2 2 1 Transposase rve PF00665.21 EIE92607.1 - 3.1e-20 72.4 0.0 1.2e-19 70.5 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 EIE92607.1 - 4.1e-11 42.6 0.3 1.2e-10 41.0 0.2 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE92607.1 - 5.2e-07 29.2 2.4 1.2e-06 28.0 1.6 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.1 EIE92607.1 - 1.3e-06 28.7 0.3 1.3e-05 25.5 0.1 2.4 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.15 EIE92607.1 - 1.2e-05 25.1 0.1 3.7e-05 23.5 0.1 1.9 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EIE92607.1 - 0.00018 21.2 0.0 0.00043 20.0 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Tudor-knot PF11717.3 EIE92607.1 - 0.0082 15.8 0.9 0.027 14.1 0.6 1.9 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Asp_protease PF09668.5 EIE92607.1 - 0.096 12.2 0.0 0.3 10.6 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease GCR1_C PF12550.3 EIE92611.1 - 5.1e-26 90.3 0.7 5.1e-25 87.1 0.2 2.6 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes DDE_Tnp_IS1595 PF12762.2 EIE92612.1 - 6.9e-15 55.1 0.0 5.6e-09 35.9 0.0 2.7 1 1 1 2 2 2 2 ISXO2-like transposase domain GerE PF00196.14 EIE92613.1 - 0.018 14.3 0.0 0.032 13.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family HTH_29 PF13551.1 EIE92613.1 - 0.059 13.5 0.0 0.097 12.8 0.0 1.4 1 1 0 1 1 1 0 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.13 EIE92614.1 - 1e-07 31.9 1.6 1.9e-07 31.0 0.5 1.9 2 0 0 2 2 2 1 Transposase HTH_Tnp_4 PF13613.1 EIE92614.1 - 0.00028 20.3 0.0 0.00058 19.3 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease HTH_23 PF13384.1 EIE92614.1 - 0.0017 17.9 0.0 0.0048 16.5 0.0 1.8 1 0 0 1 1 1 1 Homeodomain-like domain DUF520 PF04461.8 EIE92614.1 - 0.18 11.6 0.8 0.23 11.2 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF520) RVT_1 PF00078.22 EIE92615.1 - 5.3e-17 61.9 0.2 1.1e-16 60.8 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EIE92615.1 - 4.2e-16 59.1 0.0 4.4e-15 55.8 0.0 2.6 2 0 0 2 2 2 1 Integrase core domain Asp_protease_2 PF13650.1 EIE92615.1 - 1.7e-07 31.6 0.0 4.2e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 EIE92615.1 - 4.2e-07 29.8 0.1 3e-06 27.0 0.0 2.5 2 0 0 2 2 2 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EIE92615.1 - 0.00076 19.2 0.0 0.0018 18.0 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.5 EIE92615.1 - 0.0089 15.5 0.1 0.024 14.1 0.1 1.7 1 0 0 1 1 1 1 Aspartyl protease PMC2NT PF08066.7 EIE92615.1 - 0.039 14.2 0.9 10 6.4 0.0 3.0 2 0 0 2 2 2 0 PMC2NT (NUC016) domain FlxA PF14282.1 EIE92615.1 - 0.72 9.8 6.0 0.35 10.8 1.1 2.8 2 1 0 2 2 2 0 FlxA-like protein Retrotrans_gag PF03732.12 EIE92615.1 - 2.6 8.1 6.5 1.7 8.7 0.1 3.9 4 0 0 4 4 4 0 Retrotransposon gag protein DDE_3 PF13358.1 EIE92617.1 - 4.3e-21 75.2 0.4 5.9e-21 74.7 0.3 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE92618.1 - 5.9e-20 71.5 0.0 2.4e-19 69.5 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 EIE92618.1 - 3.6e-11 42.8 0.3 1e-10 41.3 0.2 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE92618.1 - 1.3e-06 27.9 2.2 3e-06 26.8 1.5 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.1 EIE92618.1 - 1.5e-06 28.6 0.1 1.6e-05 25.2 0.1 2.4 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.15 EIE92618.1 - 6.5e-06 25.9 0.1 2.1e-05 24.3 0.1 1.9 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EIE92618.1 - 0.00011 21.9 0.0 0.00025 20.8 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Tudor-knot PF11717.3 EIE92618.1 - 0.019 14.6 0.8 0.063 12.9 0.5 1.9 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain Asp_protease PF09668.5 EIE92618.1 - 0.07 12.6 0.0 0.24 10.9 0.0 1.9 1 0 0 1 1 1 0 Aspartyl protease Cut8_M PF14483.1 EIE92620.1 - 0.047 13.5 0.1 0.22 11.3 0.0 2.1 2 0 0 2 2 2 0 Cut8 dimerisation domain Retrotrans_gag PF03732.12 EIE92621.1 - 0.062 13.3 0.1 0.062 13.3 0.0 2.1 2 1 0 2 2 2 0 Retrotransposon gag protein HTH_Tnp_Tc3_2 PF01498.13 EIE92622.1 - 3.5e-08 33.3 0.3 3.5e-08 33.3 0.2 2.1 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 EIE92622.1 - 0.00034 20.7 1.9 0.00073 19.6 1.3 1.6 1 1 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_ISL3 PF13542.1 EIE92622.1 - 0.0069 15.5 2.0 0.023 13.8 0.5 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_32 PF13565.1 EIE92622.1 - 0.055 14.2 2.8 0.066 14.0 0.9 2.0 2 0 0 2 2 2 0 Homeodomain-like domain HTH_12 PF08461.5 EIE92622.1 - 0.06 13.0 0.1 0.19 11.4 0.1 1.8 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain DUF4330 PF14221.1 EIE92622.1 - 0.11 12.3 0.1 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4330) HTH_23 PF13384.1 EIE92622.1 - 0.12 12.0 2.9 1.7 8.3 0.2 2.5 2 0 0 2 2 2 0 Homeodomain-like domain HTH_21 PF13276.1 EIE92622.1 - 0.19 11.7 3.2 0.61 10.1 0.1 2.3 2 0 0 2 2 2 0 HTH-like domain RVT_1 PF00078.22 EIE92623.1 - 3.8e-29 101.5 0.2 6.8e-29 100.7 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Cut8_M PF14483.1 EIE92624.1 - 0.051 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Cut8 dimerisation domain rve PF00665.21 EIE92626.1 - 9.4e-28 96.7 0.0 2e-27 95.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 EIE92626.1 - 1.3e-05 24.6 0.0 3.2e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.5 EIE92626.1 - 0.0014 17.9 0.4 0.0033 16.7 0.3 1.6 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger RVT_1 PF00078.22 EIE92627.1 - 1e-28 100.2 0.4 2.2e-28 99.1 0.2 1.6 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease PF09668.5 EIE92627.1 - 3e-10 39.7 0.0 5.7e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 EIE92627.1 - 5.1e-09 36.5 0.1 2.2e-08 34.4 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.15 EIE92627.1 - 1.6e-06 27.9 0.1 4.6e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EIE92627.1 - 2.3e-06 27.3 0.1 5.2e-06 26.1 0.1 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 EIE92627.1 - 2.8e-05 24.0 0.0 5.2e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Spuma_A9PTase PF03539.9 EIE92627.1 - 0.0031 17.4 0.5 0.06 13.2 0.1 2.8 2 1 0 2 2 2 1 Spumavirus aspartic protease (A9) DUF4592 PF15262.1 EIE92627.1 - 1.8 9.1 5.6 4 8.0 3.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4592) CDC45 PF02724.9 EIE92627.1 - 4 5.3 10.3 6.3 4.7 7.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Retrotrans_gag PF03732.12 EIE92628.1 - 0.0027 17.7 7.8 0.0071 16.3 0.0 2.7 2 1 0 2 2 2 1 Retrotransposon gag protein rve PF00665.21 EIE92630.1 - 3.6e-27 94.8 0.0 1.2e-26 93.2 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.1 EIE92630.1 - 1.9e-05 24.0 0.0 4.3e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE92631.1 - 1.2e-18 67.2 0.4 1.7e-08 34.1 0.1 2.4 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) PNK3P PF08645.6 EIE92631.1 - 0.0081 15.6 0.1 0.97 8.8 0.0 2.4 1 1 1 2 2 2 2 Polynucleotide kinase 3 phosphatase RepB PF07506.6 EIE92633.1 - 0.029 14.2 0.0 0.031 14.1 0.0 1.0 1 0 0 1 1 1 0 RepB plasmid partitioning protein HTH_30 PF13556.1 EIE92633.1 - 0.031 13.8 0.0 0.08 12.5 0.0 1.6 1 1 1 2 2 2 0 PucR C-terminal helix-turn-helix domain Transposase_21 PF02992.9 EIE92635.1 - 1.1e-08 34.4 0.0 2.8e-07 29.8 0.0 2.3 1 1 1 2 2 2 1 Transposase family tnp2 DUF3713 PF12506.3 EIE92635.1 - 0.00018 21.5 0.4 0.00048 20.1 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3713) TGS PF02824.16 EIE92635.1 - 0.021 14.6 0.0 5 7.0 0.0 2.8 2 1 0 2 2 2 0 TGS domain Exo70 PF03081.10 EIE92636.1 - 0.16 10.7 0.1 0.21 10.3 0.1 1.1 1 0 0 1 1 1 0 Exo70 exocyst complex subunit GCR1_C PF12550.3 EIE92637.1 - 5.1e-26 90.3 0.7 5.1e-25 87.1 0.2 2.6 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes FlgM PF04316.8 EIE92639.1 - 1.3 8.9 4.0 3.2 7.7 2.8 1.6 1 0 0 1 1 1 0 Anti-sigma-28 factor, FlgM SHR3_chaperone PF08229.6 EIE92640.1 - 0.058 12.3 0.1 0.13 11.1 0.1 1.6 1 0 0 1 1 1 0 ER membrane protein SH3 MarR PF01047.17 EIE92641.1 - 0.013 15.1 0.7 5.4 6.7 0.2 2.3 2 0 0 2 2 2 0 MarR family Sigma54_DBD PF04552.8 EIE92641.1 - 0.039 13.4 0.1 0.18 11.2 0.1 2.0 1 1 0 1 1 1 0 Sigma-54, DNA binding domain TrmB PF01978.14 EIE92641.1 - 0.043 13.5 2.2 5.9 6.6 0.5 2.3 1 1 1 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_38 PF13936.1 EIE92641.1 - 0.073 12.6 0.3 0.16 11.5 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain MarR_2 PF12802.2 EIE92641.1 - 0.16 11.6 0.5 11 5.8 0.2 2.2 2 0 0 2 2 2 0 MarR family RVT_1 PF00078.22 EIE92642.1 - 2.6e-08 33.5 0.0 2.6e-08 33.4 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF805 PF05656.9 EIE92643.1 - 0.065 13.0 0.0 0.068 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF805) DDE_3 PF13358.1 EIE92644.1 - 9.1e-18 64.4 0.1 1.7e-17 63.5 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE92644.1 - 3.2e-06 27.1 3.8 1.2e-05 25.3 2.3 2.3 2 1 0 2 2 2 1 Transposase HTH_29 PF13551.1 EIE92644.1 - 0.00051 20.1 0.1 0.00081 19.5 0.1 1.3 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EIE92644.1 - 0.0012 18.4 0.0 0.0033 17.0 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_7 PF02796.10 EIE92644.1 - 0.0082 15.9 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_30 PF13556.1 EIE92644.1 - 0.0082 15.7 0.0 0.14 11.7 0.0 2.2 2 0 0 2 2 2 1 PucR C-terminal helix-turn-helix domain HTH_38 PF13936.1 EIE92644.1 - 0.023 14.2 0.0 0.088 12.3 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Crp_2 PF13545.1 EIE92644.1 - 0.16 11.8 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain DUF1884 PF08967.5 EIE92645.1 - 0.066 13.2 0.1 0.099 12.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1884) Lzipper-MIP1 PF14389.1 EIE92646.1 - 0.0049 16.9 0.4 0.013 15.5 0.3 1.7 1 0 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 ChaB PF06150.7 EIE92646.1 - 0.07 12.9 0.6 0.25 11.1 0.1 2.2 2 0 0 2 2 2 0 ChaB IncA PF04156.9 EIE92646.1 - 0.16 11.5 1.2 0.27 10.8 0.8 1.4 1 0 0 1 1 1 0 IncA protein SRR PF07709.6 EIE92646.1 - 0.23 11.7 4.4 5.5 7.6 0.0 3.6 3 0 0 3 3 3 0 Seven Residue Repeat Transposase_21 PF02992.9 EIE92647.1 - 1.4e-22 79.9 0.1 1.4e-22 79.9 0.1 1.6 2 0 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.1 EIE92647.1 - 5.4e-05 22.6 0.3 0.00012 21.5 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Flavi_capsid PF01003.14 EIE92648.1 - 0.026 14.0 0.0 0.04 13.4 0.0 1.4 1 0 0 1 1 1 0 Flavivirus capsid protein C DUF569 PF04601.8 EIE92648.1 - 0.1 12.0 0.2 0.35 10.2 0.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF569) HTH_Tnp_Tc3_2 PF01498.13 EIE92649.1 - 8e-06 25.8 0.3 1e-05 25.5 0.2 1.1 1 0 0 1 1 1 1 Transposase DDE_Tnp_ISAZ013 PF07592.6 EIE92649.1 - 0.091 11.4 0.2 0.091 11.4 0.1 1.0 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain Galactosyl_T PF01762.16 EIE92649.1 - 0.1 12.1 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Galactosyltransferase TRAPP PF04051.11 EIE92649.1 - 0.11 12.0 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 Transport protein particle (TRAPP) component DDE_3 PF13358.1 EIE92650.1 - 1.4e-19 70.3 0.1 1.6e-19 70.0 0.1 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EIE92651.1 - 2.1e-17 63.2 0.0 4.4e-17 62.1 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE92651.1 - 7.3e-09 35.5 1.5 1.8e-08 34.2 0.7 2.0 2 1 0 2 2 2 1 Transposase HTH_Tnp_Tc3_2 PF01498.13 EIE92652.1 - 4.8e-06 26.5 0.1 9.7e-06 25.5 0.1 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.1 EIE92652.1 - 0.00088 19.0 0.0 0.0013 18.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_IS1595 PF12762.2 EIE92654.1 - 2.7e-07 30.5 0.1 5.7e-07 29.4 0.1 1.5 1 0 0 1 1 1 1 ISXO2-like transposase domain HTH_Tnp_Tc3_2 PF01498.13 EIE92655.1 - 2.1e-05 24.4 0.8 2.1e-05 24.4 0.6 2.0 2 1 0 2 2 2 1 Transposase Syntaxin PF00804.20 EIE92656.1 - 0.025 14.7 0.3 0.029 14.5 0.2 1.1 1 0 0 1 1 1 0 Syntaxin DDE_1 PF03184.14 EIE92658.1 - 4.6e-28 97.8 0.0 8.1e-28 97.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EIE92658.1 - 2.5e-05 23.9 0.0 4.4e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.1 EIE92658.1 - 0.00071 19.3 0.0 0.0012 18.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease TACC PF05010.9 EIE92658.1 - 0.09 12.5 0.5 0.42 10.3 0.1 1.9 1 1 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC) Retrotrans_gag PF03732.12 EIE92659.1 - 0.0074 16.3 0.5 0.045 13.8 0.0 2.4 2 1 1 3 3 3 1 Retrotransposon gag protein rve PF00665.21 EIE92660.1 - 2e-17 63.3 0.0 7.9e-17 61.4 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 EIE92660.1 - 3.4e-16 59.2 0.1 7.5e-16 58.1 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE92660.1 - 4.6e-09 35.8 0.5 1.1e-08 34.5 0.3 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.1 EIE92660.1 - 2.8e-07 30.9 0.1 7.2e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 EIE92660.1 - 8.8e-07 28.7 0.1 4e-06 26.6 0.0 2.2 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EIE92660.1 - 0.00073 19.3 0.0 0.0017 18.1 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.12 EIE92660.1 - 0.0018 18.3 2.9 0.0049 16.9 0.0 3.3 4 0 0 4 4 4 1 Retrotransposon gag protein Asp_protease PF09668.5 EIE92660.1 - 0.011 15.2 0.2 0.1 12.1 0.0 2.4 2 0 0 2 2 2 0 Aspartyl protease Tudor-knot PF11717.3 EIE92660.1 - 0.021 14.5 0.1 0.081 12.6 0.1 2.0 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain IncA PF04156.9 EIE92660.1 - 1.6 8.2 6.2 4.5 6.8 4.3 1.7 1 0 0 1 1 1 0 IncA protein DDE_Tnp_IS1595 PF12762.2 EIE92661.1 - 3.5e-18 65.8 2.4 2.2e-12 47.0 0.1 3.1 2 1 0 2 2 2 2 ISXO2-like transposase domain DDE_Tnp_IS1595 PF12762.2 EIE92662.1 - 2.5e-07 30.6 0.1 4.6e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 ISXO2-like transposase domain Retrotrans_gag PF03732.12 EIE92664.1 - 3.5e-07 30.1 0.4 8.3e-07 28.9 0.1 1.8 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.18 EIE92664.1 - 0.00024 20.8 1.3 0.00043 20.0 0.9 1.5 1 0 0 1 1 1 1 Zinc knuckle Autophagy_N PF03986.8 EIE92664.1 - 0.0094 15.7 0.2 0.014 15.1 0.1 1.3 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Chromo PF00385.19 EIE92667.1 - 3.9e-09 36.0 1.5 3.9e-09 36.0 1.1 2.0 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain DDE_Tnp_4 PF13359.1 EIE92667.1 - 0.0087 15.6 0.1 0.017 14.7 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Snurportin1 PF11538.3 EIE92667.1 - 0.032 13.9 0.0 0.032 13.9 0.0 2.0 2 0 0 2 2 2 0 Snurportin1 DDE_Tnp_IS1595 PF12762.2 EIE92669.1 - 1.1e-22 80.4 0.8 2e-22 79.6 0.3 1.6 2 0 0 2 2 2 1 ISXO2-like transposase domain DDE_3 PF13358.1 EIE92671.1 - 7.4e-21 74.4 0.0 1.5e-20 73.4 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE92671.1 - 1.1e-15 57.4 1.9 2.8e-15 56.1 0.3 2.3 3 0 0 3 3 2 1 Transposase HTH_29 PF13551.1 EIE92671.1 - 2.7e-06 27.5 0.2 8.6e-06 25.8 0.2 1.9 2 0 0 2 2 1 1 Winged helix-turn helix HTH_38 PF13936.1 EIE92671.1 - 1.2e-05 24.7 0.1 3.3e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.1 EIE92671.1 - 7.6e-05 22.2 0.1 0.0028 17.2 0.0 2.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.1 EIE92671.1 - 8.5e-05 23.2 2.8 0.02 15.6 0.1 3.7 4 0 0 4 4 3 1 Homeodomain-like domain Sigma70_r4_2 PF08281.7 EIE92671.1 - 0.00054 19.3 0.6 0.024 14.0 0.0 3.2 4 0 0 4 4 4 1 Sigma-70, region 4 HTH_28 PF13518.1 EIE92671.1 - 0.0013 18.7 0.0 0.0056 16.6 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_21 PF13276.1 EIE92671.1 - 0.0014 18.6 0.1 0.13 12.2 0.0 2.8 3 0 0 3 3 3 1 HTH-like domain HTH_7 PF02796.10 EIE92671.1 - 0.0022 17.7 1.1 0.1 12.4 0.0 2.8 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase rve PF00665.21 EIE92671.1 - 0.0045 17.0 0.0 0.014 15.4 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain LacI PF00356.16 EIE92671.1 - 0.018 14.6 1.7 2.8 7.6 0.2 2.7 3 0 0 3 3 3 0 Bacterial regulatory proteins, lacI family HTH_Tnp_4 PF13613.1 EIE92671.1 - 0.022 14.2 0.1 0.057 12.9 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease CPSase_L_D3 PF02787.14 EIE92671.1 - 0.058 13.1 0.0 0.14 11.8 0.0 1.6 2 0 0 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain HTH_36 PF13730.1 EIE92671.1 - 0.074 13.1 0.4 4.1 7.6 0.0 2.9 3 0 0 3 3 2 0 Helix-turn-helix domain Sigma70_r4 PF04545.11 EIE92671.1 - 0.1 11.9 0.2 0.79 9.0 0.0 2.6 4 0 0 4 4 4 0 Sigma-70, region 4 HTH_Tnp_ISL3 PF13542.1 EIE92671.1 - 0.17 11.0 2.8 8.4 5.6 0.0 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 HTH_17 PF12728.2 EIE92671.1 - 0.2 11.9 2.4 15 5.9 0.1 3.2 3 0 0 3 3 3 0 Helix-turn-helix domain rve PF00665.21 EIE92672.1 - 3.8e-20 72.1 0.0 1.1e-19 70.7 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.19 EIE92672.1 - 1.9e-07 30.6 2.4 3.7e-07 29.7 1.6 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 EIE92672.1 - 0.0021 17.7 1.0 0.0086 15.7 0.7 2.1 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain rve_3 PF13683.1 EIE92672.1 - 0.0066 15.9 0.0 0.019 14.4 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE92673.1 - 2.8e-11 43.1 0.3 7e-11 41.8 0.2 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 EIE92673.1 - 3.1e-06 27.5 0.2 6.9e-06 26.4 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 EIE92673.1 - 8.8e-06 25.5 0.1 2.7e-05 24.0 0.1 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EIE92673.1 - 2.7e-05 23.9 0.0 6e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.5 EIE92673.1 - 0.049 13.1 0.0 0.16 11.5 0.0 1.9 1 0 0 1 1 1 0 Aspartyl protease Transposase_21 PF02992.9 EIE92674.1 - 5.8e-23 81.1 0.1 5.8e-23 81.1 0.1 1.7 2 0 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.1 EIE92674.1 - 5.4e-05 22.6 0.3 0.00012 21.5 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Lzipper-MIP1 PF14389.1 EIE92675.1 - 0.0049 16.9 0.4 0.013 15.5 0.3 1.7 1 0 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 ChaB PF06150.7 EIE92675.1 - 0.07 12.9 0.6 0.25 11.1 0.1 2.2 2 0 0 2 2 2 0 ChaB IncA PF04156.9 EIE92675.1 - 0.16 11.5 1.2 0.27 10.8 0.8 1.4 1 0 0 1 1 1 0 IncA protein DUF4404 PF14357.1 EIE92675.1 - 0.21 11.9 1.9 5.7 7.4 0.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) SRR PF07709.6 EIE92675.1 - 0.23 11.7 4.4 5.5 7.6 0.0 3.6 3 0 0 3 3 3 0 Seven Residue Repeat DDE_3 PF13358.1 EIE92676.1 - 2.3e-15 56.6 0.0 4.7e-15 55.6 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE92676.1 - 1.2e-11 44.4 0.8 2.8e-11 43.3 0.2 1.9 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 EIE92676.1 - 0.015 15.4 0.3 0.031 14.4 0.0 1.6 2 0 0 2 2 2 0 Winged helix-turn helix HTH_23 PF13384.1 EIE92676.1 - 0.03 13.9 0.3 0.081 12.5 0.2 1.7 1 0 0 1 1 1 0 Homeodomain-like domain HTH_30 PF13556.1 EIE92676.1 - 0.074 12.6 0.0 0.77 9.3 0.0 2.2 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain PIN_4 PF13638.1 EIE92677.1 - 8e-13 48.6 1.3 2.1e-12 47.2 0.9 1.7 1 0 0 1 1 1 1 PIN domain RNB PF00773.14 EIE92677.1 - 2.1e-07 30.5 0.0 3.8e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 RNB domain Bystin PF05291.6 EIE92677.1 - 0.037 12.9 0.0 0.38 9.6 0.0 2.1 2 0 0 2 2 2 0 Bystin GCR1_C PF12550.3 EIE92678.1 - 5.1e-26 90.3 0.7 5.1e-25 87.1 0.2 2.6 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes Aminotran_1_2 PF00155.16 EIE92679.1 - 2.3e-27 95.9 0.0 2.5e-27 95.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 EIE92679.1 - 5.1e-08 31.8 0.0 8.7e-08 31.1 0.0 1.3 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Retrotrans_gag PF03732.12 EIE92680.1 - 2.6e-05 24.2 0.1 4.6e-05 23.4 0.1 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein FYDLN_acid PF09538.5 EIE92680.1 - 0.056 14.0 0.1 0.11 13.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) rve PF00665.21 EIE92681.1 - 1.1e-18 67.4 0.0 2.5e-18 66.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE92681.1 - 2.7e-16 59.5 0.5 6.1e-16 58.4 0.1 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE92681.1 - 1.7e-13 50.0 1.8 4.4e-13 48.6 1.3 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Transposase_21 PF02992.9 EIE92682.1 - 1.8e-21 76.2 0.0 1.8e-21 76.2 0.0 2.0 3 0 0 3 3 3 1 Transposase family tnp2 DUF1258 PF06869.7 EIE92682.1 - 0.0024 16.9 0.3 0.0055 15.8 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1258) ET PF01684.11 EIE92683.1 - 1.9 8.6 13.3 4.7 7.3 1.4 2.5 2 0 0 2 2 2 0 ET module Toxin_19 PF08088.7 EIE92683.1 - 5.1 7.0 21.9 5.2 7.0 4.7 2.4 2 0 0 2 2 2 0 Conotoxin I-superfamily UDPGT PF00201.13 EIE92684.1 - 1e-35 123.2 0.0 5e-35 121.0 0.0 1.9 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_trans_1_3 PF13528.1 EIE92684.1 - 2.4e-06 26.9 0.0 0.005 16.0 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 1 Glyco_tran_28_C PF04101.11 EIE92684.1 - 1.3e-05 24.9 0.0 2.5e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glycos_transf_1 PF00534.15 EIE92684.1 - 0.016 14.6 0.0 0.043 13.2 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EIE92684.1 - 0.026 14.6 0.0 0.14 12.2 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferases group 1 tRNA_int_endo_N PF02778.9 EIE92684.1 - 0.046 13.2 0.0 1 8.9 0.0 2.5 2 0 0 2 2 2 0 tRNA intron endonuclease, N-terminal domain TPR_MLP1_2 PF07926.7 EIE92686.1 - 0.028 14.1 0.9 0.059 13.1 0.6 1.6 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein LRR_4 PF12799.2 EIE92686.1 - 0.06 12.9 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) rve PF00665.21 EIE92687.1 - 3.7e-19 68.9 0.0 9e-19 67.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE92687.1 - 6.3e-17 61.6 0.9 1.2e-16 60.6 0.2 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE92687.1 - 4.1e-14 51.9 1.1 1.2e-13 50.4 0.7 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.1 EIE92687.1 - 4.7e-06 27.0 0.1 1e-05 25.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 EIE92687.1 - 4.7e-05 23.2 0.2 0.00016 21.5 0.2 1.9 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.6 EIE92687.1 - 0.011 15.6 0.1 0.024 14.5 0.1 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease F_actin_bind PF08919.5 EIE92687.1 - 0.016 14.8 0.0 0.12 12.1 0.0 2.5 1 0 0 1 1 1 0 F-actin binding DDE_3 PF13358.1 EIE92688.1 - 3.1e-15 56.1 0.0 6e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE92688.1 - 2.7e-11 43.3 0.9 5.2e-11 42.4 0.2 1.9 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.1 EIE92688.1 - 0.016 14.8 0.1 0.042 13.4 0.1 1.7 1 0 0 1 1 1 0 Homeodomain-like domain HTH_29 PF13551.1 EIE92688.1 - 0.017 15.2 0.2 0.039 14.0 0.0 1.7 2 0 0 2 2 2 0 Winged helix-turn helix HTH_30 PF13556.1 EIE92688.1 - 0.05 13.2 0.0 0.51 9.9 0.0 2.2 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain DDE_3 PF13358.1 EIE92689.1 - 8.3e-21 74.2 0.0 1.3e-20 73.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE92689.1 - 3e-15 56.0 0.2 7.6e-15 54.7 0.1 1.7 2 0 0 2 2 2 1 Transposase rve PF00665.21 EIE92689.1 - 0.0048 16.9 0.0 0.011 15.8 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain HTH_32 PF13565.1 EIE92689.1 - 0.011 16.5 0.7 0.27 12.0 0.0 2.9 3 0 0 3 3 3 0 Homeodomain-like domain HTH_29 PF13551.1 EIE92689.1 - 0.023 14.8 0.2 0.079 13.1 0.1 2.0 2 0 0 2 2 2 0 Winged helix-turn helix HTH_21 PF13276.1 EIE92689.1 - 0.029 14.3 0.1 0.11 12.4 0.0 2.0 2 0 0 2 2 2 0 HTH-like domain Glyco_hydro_47 PF01532.15 EIE92691.1 - 1e-150 502.3 0.6 7.2e-78 262.2 0.1 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 47 Glyco_hydro_76 PF03663.9 EIE92691.1 - 0.0071 15.7 0.3 2.6 7.3 0.0 2.3 2 0 0 2 2 2 2 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 EIE92691.1 - 0.024 13.7 0.1 1 8.3 0.0 2.3 2 1 0 2 2 2 0 Glycosyl Hydrolase Family 88 Mito_carr PF00153.22 EIE92692.1 - 1e-21 76.4 0.1 1.9e-16 59.5 0.0 2.2 2 0 0 2 2 2 2 Mitochondrial carrier protein rve PF00665.21 EIE92693.1 - 8.7e-18 64.5 0.0 1.9e-17 63.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 EIE92693.1 - 5.5e-10 38.7 0.6 1.2e-09 37.7 0.4 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 EIE92693.1 - 0.0094 15.6 1.4 0.012 15.3 0.1 1.8 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain rve PF00665.21 EIE92694.1 - 8.3e-19 67.8 0.0 2e-18 66.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE92694.1 - 2.3e-16 59.8 0.7 4.5e-16 58.8 0.1 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE92694.1 - 7.6e-14 51.1 2.2 1.9e-13 49.8 1.5 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DDE_3 PF13358.1 EIE92695.1 - 8.9e-12 44.9 0.4 1.5e-11 44.2 0.3 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Toxin_56 PF15534.1 EIE92696.1 - 0.35 11.3 7.8 0.25 11.8 1.4 2.7 1 1 1 2 2 2 0 Putative toxin 56 DDE_3 PF13358.1 EIE92697.1 - 3e-16 59.5 0.1 5e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE92697.1 - 7.9e-14 51.4 0.3 2.4e-13 49.9 0.2 1.9 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.1 EIE92697.1 - 3.5e-05 23.9 0.4 7e-05 22.9 0.3 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EIE92697.1 - 0.00021 20.8 0.2 0.0025 17.4 0.0 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_7 PF02796.10 EIE92697.1 - 0.0005 19.8 0.4 0.068 13.0 0.1 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase rve PF00665.21 EIE92697.1 - 0.0093 16.0 0.0 0.026 14.6 0.0 1.9 1 1 0 1 1 1 1 Integrase core domain DDE_3 PF13358.1 EIE92698.1 - 1.6e-17 63.5 0.4 8.9e-17 61.1 0.0 2.3 3 0 0 3 3 3 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE92698.1 - 1.8e-11 43.9 0.6 4.1e-11 42.7 0.4 1.7 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.1 EIE92698.1 - 0.02 15.6 0.1 0.88 10.4 0.0 2.9 3 0 0 3 3 3 0 Homeodomain-like domain HTH_29 PF13551.1 EIE92698.1 - 0.04 14.0 0.0 0.11 12.6 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn helix DDE_3 PF13358.1 EIE92704.1 - 1e-17 64.2 0.1 2.5e-17 62.9 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE92704.1 - 5.4e-12 45.5 1.0 5.4e-12 45.5 0.7 2.2 3 0 0 3 3 3 1 Transposase HTH_29 PF13551.1 EIE92704.1 - 0.0002 21.4 0.7 0.0004 20.5 0.1 1.8 2 0 0 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.1 EIE92704.1 - 0.00095 18.7 0.1 0.0025 17.3 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_7 PF02796.10 EIE92704.1 - 0.008 16.0 0.0 0.021 14.6 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_30 PF13556.1 EIE92704.1 - 0.012 15.1 0.0 0.17 11.4 0.0 2.2 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain HTH_38 PF13936.1 EIE92704.1 - 0.029 13.9 0.0 0.11 12.0 0.0 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain RecX PF02631.11 EIE92704.1 - 0.13 12.4 0.3 0.27 11.4 0.2 1.5 1 0 0 1 1 1 0 RecX family TraF_2 PF13729.1 EIE92706.1 - 0.0099 14.7 1.1 0.026 13.3 0.3 1.8 2 0 0 2 2 2 1 F plasmid transfer operon, TraF, protein DUF3713 PF12506.3 EIE92707.1 - 0.00012 22.1 0.4 0.00025 21.1 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3713) TGS PF02824.16 EIE92707.1 - 0.0059 16.4 0.0 2.9 7.8 0.0 2.9 2 1 0 2 2 2 2 TGS domain MRL1 PF13003.2 EIE92709.1 - 0.015 15.1 0.0 0.018 14.8 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L1 rve PF00665.21 EIE92710.1 - 1.2e-24 86.6 0.0 4.3e-24 84.9 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE92710.1 - 6.7e-17 61.5 0.0 1.4e-16 60.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.5 EIE92710.1 - 0.00061 19.1 1.3 0.00082 18.7 0.1 2.0 2 0 0 2 2 2 1 His(2)-Cys(2) zinc finger rve_3 PF13683.1 EIE92710.1 - 0.023 14.1 0.0 0.068 12.6 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain Retrotrans_gag PF03732.12 EIE92710.1 - 0.28 11.2 1.3 1.3 9.1 0.0 2.7 4 0 0 4 4 4 0 Retrotransposon gag protein DDE_3 PF13358.1 EIE92711.1 - 1.1e-20 73.9 1.0 1.3e-20 73.6 0.3 1.4 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EIE92712.1 - 2.4e-05 24.0 0.0 3.5e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain TACC PF05010.9 EIE92712.1 - 0.095 12.4 0.2 0.1 12.3 0.1 1.1 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) Asp_protease_2 PF13650.1 EIE92713.1 - 6.5e-05 23.3 0.1 0.00016 22.0 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 EIE92713.1 - 0.00024 20.9 0.1 0.00072 19.4 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EIE92713.1 - 0.032 14.0 0.0 0.061 13.1 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DDE_Tnp_IS1595 PF12762.2 EIE92714.1 - 3.4e-06 26.9 0.1 6.2e-06 26.1 0.1 1.4 1 1 0 1 1 1 1 ISXO2-like transposase domain RVT_1 PF00078.22 EIE92715.1 - 0.00028 20.3 0.1 0.00081 18.7 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EIE92716.1 - 1.2e-19 70.5 0.0 3.1e-19 69.2 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.19 EIE92716.1 - 2.1e-14 52.9 1.1 4.1e-14 51.9 0.7 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RNase_H PF00075.19 EIE92716.1 - 0.013 15.7 0.0 0.078 13.3 0.0 2.2 2 0 0 2 2 2 0 RNase H SSDP PF04503.8 EIE92717.1 - 1.3 8.6 6.4 1.6 8.3 4.4 1.0 1 0 0 1 1 1 0 Single-stranded DNA binding protein, SSDP DDE_Tnp_IS1595 PF12762.2 EIE92719.1 - 7e-15 55.1 0.0 5.6e-09 35.9 0.0 2.7 1 1 1 2 2 2 2 ISXO2-like transposase domain FKBP_N PF01346.13 EIE92721.1 - 0.011 15.7 1.9 0.011 15.7 1.3 2.1 3 0 0 3 3 3 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase YebO PF13974.1 EIE92721.1 - 0.036 13.8 7.2 0.87 9.4 0.0 2.5 2 0 0 2 2 2 0 YebO-like protein LAG1-DNAbind PF09271.6 EIE92721.1 - 0.094 13.1 0.4 0.094 13.1 0.3 1.7 2 0 0 2 2 2 0 LAG1, DNA binding HTH_37 PF13744.1 EIE92721.1 - 4.1 7.2 9.2 45 3.9 5.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain Transposase_21 PF02992.9 EIE92722.1 - 6.8e-22 77.6 0.0 1e-21 77.0 0.0 1.2 1 0 0 1 1 1 1 Transposase family tnp2 DUF1258 PF06869.7 EIE92722.1 - 0.0019 17.3 0.0 0.0031 16.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) LysR_substrate PF03466.15 EIE92722.1 - 0.15 11.1 0.0 0.27 10.2 0.0 1.3 1 0 0 1 1 1 0 LysR substrate binding domain DUF1759 PF03564.10 EIE92723.1 - 0.00038 20.2 0.2 0.00045 20.0 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) DDE_3 PF13358.1 EIE92724.1 - 3.9e-14 52.6 0.0 6.1e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF2567 PF10821.3 EIE92724.1 - 0.15 11.5 0.0 0.2 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2567) DDE_3 PF13358.1 EIE92725.1 - 5.2e-11 42.5 2.4 5.2e-11 42.5 1.6 1.3 1 1 0 1 1 1 1 DDE superfamily endonuclease NDUF_B6 PF09782.4 EIE92725.1 - 0.038 13.8 0.7 0.089 12.6 0.5 1.7 1 1 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit DUF2774 PF11242.3 EIE92725.1 - 0.13 12.2 0.1 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2774) DUF2695 PF10905.3 EIE92725.1 - 0.5 10.1 2.5 2.9 7.6 0.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2695) rve PF00665.21 EIE92726.1 - 1.8e-23 82.9 0.0 2.2e-22 79.4 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 EIE92726.1 - 2e-16 60.0 0.0 4e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE92726.1 - 2.4e-11 43.1 0.2 5.8e-11 41.9 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.1 EIE92726.1 - 4.9e-06 26.9 0.0 1.9e-05 25.0 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease Retrotrans_gag PF03732.12 EIE92726.1 - 5.4e-06 26.3 0.1 1.8e-05 24.6 0.0 2.0 1 0 0 1 1 1 1 Retrotransposon gag protein UBN2_2 PF14227.1 EIE92726.1 - 3.3e-05 23.4 0.2 0.00098 18.6 0.1 3.2 3 1 0 3 3 3 1 gag-polypeptide of LTR copia-type gag-asp_proteas PF13975.1 EIE92726.1 - 0.00021 21.0 0.0 0.00043 20.0 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.5 EIE92726.1 - 0.0074 15.6 0.1 0.026 13.9 0.0 2.0 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger UBN2 PF14223.1 EIE92726.1 - 0.065 13.0 0.1 0.23 11.2 0.1 1.9 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type Mto2_bdg PF12808.2 EIE92728.1 - 2.3 8.3 8.5 5.9 7.0 0.1 3.6 4 0 0 4 4 4 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Transposase_21 PF02992.9 EIE92729.1 - 2.2e-22 79.2 0.1 2.2e-22 79.2 0.1 1.6 2 0 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.1 EIE92729.1 - 4.4e-05 22.9 0.4 9.6e-05 21.8 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Asp_protease_2 PF13650.1 EIE92730.1 - 2.9e-06 27.6 0.0 7.7e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.5 EIE92730.1 - 0.00087 18.8 0.0 0.0017 17.9 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EIE92730.1 - 0.003 17.3 0.1 0.0059 16.4 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Mod_r PF07200.8 EIE92731.1 - 0.00019 21.3 0.1 0.00031 20.7 0.0 1.3 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Matrilin_ccoil PF10393.4 EIE92731.1 - 0.017 14.4 0.2 0.037 13.4 0.2 1.5 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin Reo_sigmaC PF04582.7 EIE92731.1 - 0.068 12.3 2.3 0.094 11.8 1.6 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein TMF_DNA_bd PF12329.3 EIE92731.1 - 0.082 12.7 3.9 0.55 10.0 0.6 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4164 PF13747.1 EIE92731.1 - 0.19 11.9 6.3 0.73 10.0 1.5 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) rve PF00665.21 EIE92732.1 - 8.7e-14 51.6 0.0 9.5e-14 51.5 0.0 1.0 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 EIE92732.1 - 0.00059 19.3 0.0 0.00094 18.6 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain DDE_3 PF13358.1 EIE92733.1 - 1.6e-18 66.8 0.0 3.9e-18 65.6 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE92733.1 - 3.3e-09 36.6 0.6 1.3e-08 34.7 0.7 1.9 2 0 0 2 2 2 1 Transposase RVT_1 PF00078.22 EIE92734.1 - 1.7e-15 57.0 0.3 4.3e-15 55.6 0.2 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.12 EIE92734.1 - 0.00032 20.7 1.3 0.0014 18.6 0.7 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein zf-H2C2 PF09337.5 EIE92734.1 - 0.0011 18.3 0.1 0.0032 16.8 0.1 1.9 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Asp_protease_2 PF13650.1 EIE92734.1 - 0.0051 17.2 0.2 0.012 16.1 0.2 1.7 1 0 0 1 1 1 1 Aspartyl protease UBN2_2 PF14227.1 EIE92734.1 - 0.016 14.7 4.7 0.087 12.3 0.0 3.3 3 0 0 3 3 3 0 gag-polypeptide of LTR copia-type Asp_protease PF09668.5 EIE92734.1 - 0.025 14.1 0.1 0.082 12.4 0.1 1.9 1 1 0 1 1 1 0 Aspartyl protease DUF2246 PF10229.4 EIE92734.1 - 0.03 13.6 0.1 0.03 13.6 0.0 2.5 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2246) YrhC PF14143.1 EIE92735.1 - 0.085 12.8 0.4 0.14 12.0 0.1 1.5 2 0 0 2 2 2 0 YrhC-like protein DUF4534 PF15049.1 EIE92735.1 - 0.1 12.1 4.5 0.12 12.0 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4534) HTH_Tnp_Tc3_2 PF01498.13 EIE92736.1 - 1.9e-07 31.0 0.4 5.8e-07 29.4 0.1 1.8 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 EIE92736.1 - 0.00059 19.9 0.1 0.0014 18.7 0.1 1.6 2 0 0 2 2 2 1 Winged helix-turn helix HTH_17 PF12728.2 EIE92736.1 - 0.027 14.7 0.0 0.042 14.0 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.1 EIE92736.1 - 0.13 11.9 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain DDE_3 PF13358.1 EIE92737.1 - 4.4e-19 68.6 0.0 8.2e-19 67.7 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIE92737.1 - 1.7e-09 37.5 1.0 6.9e-09 35.6 0.7 2.1 1 0 0 1 1 1 1 Transposase HTH_Tnp_4 PF13613.1 EIE92737.1 - 0.00075 18.9 0.0 0.0014 18.0 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease HTH_23 PF13384.1 EIE92737.1 - 0.004 16.7 0.0 0.013 15.1 0.0 1.9 1 0 0 1 1 1 1 Homeodomain-like domain FAM70 PF14967.1 EIE92737.1 - 0.05 12.8 0.0 0.076 12.1 0.0 1.2 1 0 0 1 1 1 0 FAM70 protein Transposase_21 PF02992.9 EIE92738.1 - 1.8e-20 73.0 0.0 2.9e-20 72.3 0.0 1.2 1 0 0 1 1 1 1 Transposase family tnp2 DUF1258 PF06869.7 EIE92738.1 - 0.042 12.9 0.0 0.066 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1258) LysR_substrate PF03466.15 EIE92738.1 - 0.15 11.1 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 LysR substrate binding domain DDE_Tnp_IS1595 PF12762.2 EIE92740.1 - 2.9e-06 27.2 0.1 5.3e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 ISXO2-like transposase domain UDG PF03167.14 EIE92741.1 - 0.075 12.4 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Uracil DNA glycosylase superfamily rve PF00665.21 EIE92742.1 - 1.1e-18 67.4 0.0 2.5e-18 66.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIE92742.1 - 3.6e-16 59.1 0.6 7.7e-16 58.0 0.1 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIE92742.1 - 9.1e-14 50.8 2.2 2.4e-13 49.5 1.5 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF2847 PF11009.3 EIE92745.1 - 0.069 12.7 0.1 0.069 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) DDE_3 PF13358.1 EIE92747.1 - 1.8e-11 43.9 0.1 2.4e-11 43.5 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF3279 PF11682.3 EIE92747.1 - 0.1 12.2 0.1 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3279) FKBP_N PF01346.13 EIE92748.1 - 0.0016 18.5 1.0 0.0033 17.4 0.7 1.5 1 0 0 1 1 1 1 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase LAG1-DNAbind PF09271.6 EIE92748.1 - 0.031 14.7 0.4 0.059 13.8 0.2 1.4 1 0 0 1 1 1 0 LAG1, DNA binding HTH_37 PF13744.1 EIE92748.1 - 1.6 8.6 7.2 19 5.1 3.7 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain YebO PF13974.1 EIE92748.1 - 9.3 6.1 10.9 19 5.1 0.1 2.4 2 0 0 2 2 2 0 YebO-like protein DDE_3 PF13358.1 EIE92749.1 - 7.1e-19 67.9 0.0 9.6e-19 67.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE92749.1 - 0.017 15.2 0.0 0.034 14.2 0.0 1.6 1 1 0 1 1 1 0 Integrase core domain Myb_DNA-bind_5 PF13873.1 EIE92749.1 - 0.057 13.3 0.7 5.2 7.0 0.2 2.5 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain DUF1033 PF06279.6 EIE92749.1 - 0.067 13.0 0.3 0.11 12.2 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1033) DDE_Tnp_IS1595 PF12762.2 EIE92750.1 - 6.3e-18 65.0 0.0 1e-17 64.3 0.0 1.3 1 0 0 1 1 1 1 ISXO2-like transposase domain DDE_3 PF13358.1 EIE92751.1 - 7.7e-14 51.6 0.3 9.6e-14 51.3 0.2 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIE92751.1 - 0.01 15.9 0.0 0.018 15.1 0.0 1.4 1 1 0 1 1 1 0 Integrase core domain DUF1033 PF06279.6 EIE92751.1 - 0.068 12.9 0.4 0.11 12.3 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1033) Myb_DNA-bind_5 PF13873.1 EIE92751.1 - 0.077 12.8 0.5 8.5 6.3 0.2 2.4 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain ELL PF10390.4 EIE92751.1 - 0.095 11.9 1.4 0.1 11.8 0.5 1.3 1 1 0 1 1 1 0 RNA polymerase II elongation factor ELL HTH_29 PF13551.1 EIE92754.1 - 0.0032 17.5 0.0 0.0042 17.2 0.0 1.2 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EIE92754.1 - 0.0048 16.5 0.1 0.0085 15.7 0.1 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_30 PF13556.1 EIE92754.1 - 0.069 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain DUF603 PF04645.7 EIE92754.1 - 0.11 12.4 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF603 HTH_Tnp_Tc3_2 PF01498.13 EIE92756.1 - 6e-09 35.8 0.4 6e-09 35.8 0.3 2.1 1 1 1 2 2 2 1 Transposase HTH_29 PF13551.1 EIE92756.1 - 0.013 15.6 1.3 0.035 14.2 0.9 1.7 1 1 0 1 1 1 0 Winged helix-turn helix HTH_32 PF13565.1 EIE92756.1 - 0.021 15.6 1.5 0.037 14.8 0.4 1.8 2 0 0 2 2 2 0 Homeodomain-like domain HTH_12 PF08461.5 EIE92756.1 - 0.039 13.6 0.0 0.092 12.4 0.0 1.6 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain HTH_Tnp_ISL3 PF13542.1 EIE92756.1 - 0.041 13.0 0.6 0.35 10.0 0.1 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_21 PF13276.1 EIE92756.1 - 0.046 13.7 1.7 0.32 11.0 0.1 2.3 2 0 0 2 2 2 0 HTH-like domain DUF569 PF04601.8 EIE92756.1 - 0.09 12.2 2.1 0.44 9.9 0.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF569) HTH_33 PF13592.1 EIE92756.1 - 0.13 11.8 0.4 0.27 10.8 0.0 1.8 2 0 0 2 2 2 0 Winged helix-turn helix